[med-svn] [Git][med-team/last-align][upstream] New upstream version 1254
Nilesh Patra (@nilesh)
gitlab at salsa.debian.org
Fri Aug 6 15:55:31 BST 2021
Nilesh Patra pushed to branch upstream at Debian Med / last-align
Commits:
1ff64d32 by Nilesh Patra at 2021-08-06T20:11:53+05:30
New upstream version 1254
- - - - -
12 changed files:
- bin/last-train
- doc/last-cookbook.rst
- doc/last-dotplot.rst
- doc/last-tuning.rst
- doc/lastdb.rst
- src/LastdbArguments.cc
- src/LastdbArguments.hh
- src/SubsetSuffixArraySearch.cc
- src/lastdb.cc
- src/makefile
- test/last-test.out
- test/last-test.sh
Changes:
=====================================
bin/last-train
=====================================
@@ -628,6 +628,15 @@ def codonScoresAndScale(originalScale, matParams, delRatios, insRatios):
matchRatio, matProbs, rowFreqs, colFreqs = matParams
rowProbs = normalizedFreqs(rowFreqs)
colProbs = normalizedFreqs(colFreqs)
+
+ r = range(4)
+ baseProbs = [sum(colProbs[v*16 + i*4 + j] +
+ colProbs[i*16 + v*4 + j] +
+ colProbs[i*16 + j*4 + v] for i in r for j in r) / 3
+ for v in r]
+ print("# % a c g t:", *(format(i * 100, ".3") for i in baseProbs))
+ print()
+
matParams = matchRatio, matProbs, rowProbs, colProbs
while True:
matScores = matScoresFromProbs(originalScale, *matParams)
@@ -771,8 +780,7 @@ def doTraining(opts, args):
if opts.b: lastalArgs.append("-b" + opts.b)
if opts.A: lastalArgs.append("-A" + opts.A)
if opts.B: lastalArgs.append("-B" + opts.B)
- lastalArgs += args
- proc = process(lastalArgs, None)
+ proc = process(lastalArgs + args, None)
proc = lastSplitProcess(opts, proc)
if not opts.scale:
outerScale = scaleFromHeader(proc.stdout)
@@ -824,8 +832,7 @@ def doTraining(opts, args):
lastalArgs = fixedLastalArgs(opts, lastalProgName)
lastalArgs.append("-t{0:.6}".format(scale))
lastalArgs.append("-p-")
- lastalArgs += args
- proc = process(lastalArgs, subprocess.PIPE)
+ proc = process(lastalArgs + args, subprocess.PIPE)
writeGapCosts(opts, delCosts, insCosts, True, proc.stdin)
writeScoreMatrixFunc(proc.stdin, matScores, "")
proc.stdin.close()
=====================================
doc/last-cookbook.rst
=====================================
@@ -220,17 +220,13 @@ Aligning Illumina DNA reads to a genome
::
- lastdb -P8 -uNEAR -C2 mydb genome.fasta
+ lastdb -P8 -uNEAR mydb genome.fasta
last-train -P8 -Q1 mydb reads.fastq.gz > reads.train
lastal -P8 -p reads.train mydb reads.fastq.gz | last-split | gzip > out.maf.gz
Most LAST commands accept ``.gz`` compressed files, and you can
compress output with ``gzip`` as above.
-lastdb_ option ``-C2`` makes the alignment a bit faster, but uses more
-memory. This has no effect on the results. (You could use it in the
-other examples too, but it might not be faster.)
-
``-Q1`` makes it use the fastq_ quality information to improve the
training and alignment. LAST **assumes** that the qualities reflect
substitution errors, not insertion/deletion errors. (For long
=====================================
doc/last-dotplot.rst
=====================================
@@ -221,7 +221,7 @@ Colors
------
Colors can be specified in `various ways described here
-<http://effbot.org/imagingbook/imagecolor.htm>`_.
+<https://pillow.readthedocs.io/en/stable/reference/ImageColor.html>`_.
.. _Python Imaging Library: https://pillow.readthedocs.io/
.. _BED-format: https://genome.ucsc.edu/FAQ/FAQformat.html#format1
=====================================
doc/last-tuning.rst
=====================================
@@ -156,9 +156,10 @@ If lastdb is too slow, try ``-i10``.
lastdb -C2
----------
-This option may make lastal a bit **faster**, but **uses more memory
-and disk**, and makes lastdb slower. It has no effect on the results.
-If the downsides are no problem, you may as well try it.
+**Obsolete(?)** This made old versions (< 1253) of lastal faster, but
+makes new versions of lastal slower. If you already used this option,
+you can undo it by deleting the ``.chi2`` files (or move/rename them
+to test which is faster).
lastdb -B
---------
=====================================
doc/lastdb.rst
=====================================
@@ -222,13 +222,15 @@ Advanced Options
Specify the type of "child table" to make: 0 means none, 1 means
byte-size (uses a little more memory), 2 means short-size (uses
somewhat more memory), 3 means full (uses a lot more memory).
- Choices > 0 make lastal a bit faster, but make lastdb slower,
- and have no effect on lastal's results. Some tests suggest that
- -C2 is a good choice: faster than -C1 and no slower than -C3.
+ Choices > 0 make lastdb slower, and have no effect on lastal's
+ results. This option seems to be mostly obsolete: it used to make
+ lastal faster, but now makes it slower (sometimes).
-x Just count sequences and letters. This is much faster. Letter
counting is never case-sensitive.
+-D Read pre-existing lastdb files, and print all the sequences in them.
+
-v Be verbose: write messages about what lastdb is doing.
-V, --version
=====================================
src/LastdbArguments.cc
=====================================
@@ -44,6 +44,7 @@ LastdbArguments::LastdbArguments() :
minIndexedPositionsPerBucket(4),
childTableType(0),
isCountsOnly(false),
+ isDump(false),
verbosity(0),
inputFormat(sequenceFormat::fasta){}
@@ -85,11 +86,12 @@ Advanced Options (default settings):\n\
-C: child table type: 0=none, 1=byte-size, 2=short-size, 3=full ("
+ stringify(childTableType) + ")\n\
-x: just count sequences and letters\n\
+-D: print all sequences in lastdb files\n\
-v: be verbose: write messages about what lastdb is doing\n\
-V, --version: show version information, and exit\n\
";
- static const char sOpts[] = "hVpqR:cm:d:S:s:w:W:P:u:a:i:b:B:C:xvQ:";
+ static const char sOpts[] = "hVpqR:cm:d:S:s:w:W:P:u:a:i:b:B:C:xDvQ:";
int c;
while ((c = myGetopt(argc, argv, sOpts)) != -1) {
@@ -165,6 +167,9 @@ Advanced Options (default settings):\n\
case 'x':
isCountsOnly = true;
break;
+ case 'D':
+ isDump = true;
+ break;
case 'v':
++verbosity;
break;
=====================================
src/LastdbArguments.hh
=====================================
@@ -53,6 +53,7 @@ struct LastdbArguments{
size_t minIndexedPositionsPerBucket;
int childTableType;
bool isCountsOnly;
+ bool isDump;
int verbosity;
sequenceFormat::Enum inputFormat;
=====================================
src/SubsetSuffixArraySearch.cc
=====================================
@@ -225,6 +225,113 @@ static void equalRange2(const PosPart *sufArray, indexT &beg, indexT &end,
}
}
+// Find the suffix array range of string [queryBeg, queryBeg+d) within
+// the suffix array range [beg, end), where d is not known in advance.
+// The routine tries to find a large-as-possible d: it guarantees that
+// the suffix array range for d-1 is longer than maxHits. d is
+// returned. Actually, this routine may find *part* of the SA range
+// of [queryBeg, queryBeg+d), which is guaranteed to include the whole
+// range for the smallest d whose range is no longer than maxHits.
+static size_t equalRange3(const PosPart *sufArray, indexT &beg, indexT &end,
+ const uchar *&subsetMap, const uchar *textBase,
+ const uchar *queryBeg, const CyclicSubsetSeed &seed,
+ size_t maxHits) {
+ if (subsetMap[*queryBeg] == CyclicSubsetSeed::DELIMITER) return 0;
+ assert(end - beg > maxHits);
+ const uchar *qBeg = queryBeg;
+ const uchar *tBeg = textBase;
+ const uchar *sBeg = subsetMap;
+ const uchar *qBegOld = qBeg;
+ const uchar *tBegOld = tBeg;
+ const uchar *sBegOld = sBeg;
+ const uchar *qEnd = queryBeg;
+ const uchar *tEnd = textBase;
+ const uchar *sEnd = subsetMap;
+ const uchar *qEndOld = qEnd;
+ const uchar *tEndOld = tEnd;
+ const uchar *sEndOld = sEnd;
+ const uchar *qMid = queryBeg;
+ const uchar *tMid = textBase;
+ const uchar *sMid = subsetMap;
+
+ while (end - beg > maxHits * 2) {
+ indexT mid = beg + (end - beg) / 2;
+ indexT offset = posGetAt(sufArray, mid);
+ tMid += offset;
+ int iterations = 1023; // xxx ???
+ uchar tChar, qChar;
+ for (;;) { // loop over consecutive letters
+ const uchar *textSubsetMap = seed.originalSubsetMap(sMid);
+ tChar = textSubsetMap[*tMid]; // this text letter's subset
+ qChar = sMid[*qMid]; // this query letter's subset
+ if (tChar != qChar || qChar == CyclicSubsetSeed::DELIMITER) break;
+ if (--iterations == 0) { // avoid huge self-comparisons
+ subsetMap = qBeg < qEnd ? sBeg : sEnd;
+ return std::min(qBeg, qEnd) - queryBeg;
+ }
+ ++qMid; // next query letter
+ ++tMid; // next text letter
+ sMid = seed.nextMap(sMid); // next mapping from letters to subsets
+ }
+ tMid -= offset;
+ if (tChar <= qChar) {
+ beg = mid + 1;
+ qBegOld = qBeg;
+ tBegOld = tBeg;
+ sBegOld = sBeg;
+ qBeg = qMid;
+ tBeg = tMid;
+ sBeg = sMid;
+ if (qEnd < qMid) {
+ if (qChar == CyclicSubsetSeed::DELIMITER && qBeg == qBegOld) {
+ beg = end;
+ return 0;
+ }
+ qMid = qEnd;
+ tMid = tEnd;
+ sMid = sEnd;
+ }
+ } else {
+ end = mid;
+ qEndOld = qEnd;
+ tEndOld = tEnd;
+ sEndOld = sEnd;
+ qEnd = qMid;
+ tEnd = tMid;
+ sEnd = sMid;
+ if (qBeg < qMid) {
+ qMid = qBeg;
+ tMid = tBeg;
+ sMid = sBeg;
+ }
+ }
+ }
+
+ if (qBeg < qEnd) {
+ qMid = std::max(qBeg, qEndOld) + 1;
+ subsetMap = seed.nextMap(qBeg > qEndOld ? sBeg : sEndOld);
+ if (qMid > qEnd) {
+ equalRange2(sufArray, beg, end, tBeg, sBeg, qBeg, qMid, seed);
+ } else {
+ beg = lowerBound2(sufArray, beg, end, tBeg, sBeg, qBeg, qMid, seed);
+ end = upperBound2(sufArray, end + 1, end + maxHits + 1,
+ tEndOld, sEndOld, qEndOld, qMid, seed);
+ }
+ } else {
+ qMid = std::max(qEnd, qBegOld) + 1;
+ subsetMap = seed.nextMap(qEnd > qBegOld ? sEnd : sBegOld);
+ if (qMid > qBeg) {
+ equalRange2(sufArray, beg, end, tEnd, sEnd, qEnd, qMid, seed);
+ } else {
+ beg = lowerBound2(sufArray, beg - maxHits - 1, beg - 1,
+ tBegOld, sBegOld, qBegOld, qMid, seed);
+ end = upperBound2(sufArray, beg, end, tEnd, sEnd, qEnd, qMid, seed);
+ }
+ }
+
+ return qMid - queryBeg;
+}
+
// use past results to speed up long matches?
// could & probably should return the match depth
void SubsetSuffixArray::match(const PosPart *&begPtr, const PosPart *&endPtr,
@@ -289,6 +396,12 @@ void SubsetSuffixArray::match(const PosPart *&begPtr, const PosPart *&endPtr,
queryPtr + d, queryPtr + depth, seed);
}
+ if (end - beg > maxHits * 2 && maxDepth + 1 == 0 &&
+ childTable.empty() && kiddyTable.empty() && chibiTable.empty()) {
+ depth += equalRange3(sufArray, beg, end, subsetMap,
+ text + depth, queryPtr + depth, seed, maxHits);
+ }
+
ChildDirection childDirection = UNKNOWN;
while( end - beg > maxHits && depth < maxDepth ){
=====================================
src/lastdb.cc
=====================================
@@ -23,6 +23,11 @@ using namespace cbrc;
typedef unsigned long long countT;
+static void openOrDie(std::ifstream &file, const std::string &name) {
+ file.open(name.c_str());
+ if (!file) ERR("can't open file: " + name);
+}
+
// Set up an alphabet (e.g. DNA or protein), based on the user options
void makeAlphabet( Alphabet& alph, const LastdbArguments& args ){
if( !args.userAlphabet.empty() ) alph.fromString( args.userAlphabet );
@@ -331,9 +336,72 @@ static bool isRoomToDuplicateTheLastSequence(const MultiSequence &multi,
return s <= maxSeqLen && s - multi.seqBeg(n - 1) <= maxSeqLen - s;
}
+static void dump1(const std::string &dbName, const uchar *decode,
+ size_t seqCount, bool isFastq) {
+ if (seqCount + 1 == 0) ERR("can't read file: " + dbName + ".prj");
+ MultiSequence m;
+ m.fromFiles(dbName, seqCount, isFastq);
+ const uchar *s = m.seqReader();
+ for (size_t i = 0; i < m.finishedSequences(); ++i) {
+ std::cout << ">@"[isFastq] << m.seqName(i) << '\n';
+ std::streambuf *buf = std::cout.rdbuf();
+ size_t e = m.seqEnd(i);
+ for (size_t j = m.seqBeg(i); j < e; ++j) {
+ buf->sputc(decode[s[j]]);
+ }
+ if (isFastq) {
+ std::cout << "\n+\n";
+ std::cout.write((char *)m.qualityReader() + m.seqBeg(i), m.seqLen(i));
+ }
+ std::cout << '\n';
+ }
+}
+
+static void dump(const std::string &dbName) {
+ std::ios_base::sync_with_stdio(false); // makes it much faster!
+ Alphabet alph;
+ unsigned volumes = -1;
+ size_t seqCount = -1;
+ size_t bitsPerInt = 4 * CHAR_BIT;
+ sequenceFormat::Enum fmt = sequenceFormat::fasta;
+ std::string line, word;
+ std::ifstream file;
+ openOrDie(file, dbName + ".prj");
+ while (getline(file, line)) {
+ std::istringstream iss(line);
+ getline(iss, word, '=');
+ if (word == "alphabet") iss >> alph;
+ if (word == "numofsequences") iss >> seqCount;
+ if (word == "sequenceformat") iss >> fmt;
+ if (word == "volumes") iss >> volumes;
+ if (word == "integersize") iss >> bitsPerInt;
+ }
+ if (alph.letters.empty()) ERR("can't read file: " + dbName + ".prj");
+ size_t b = bitsPerInt / CHAR_BIT;
+ if (posSize > 4 && b <= 4) ERR("please use lastdb for " + dbName);
+ if (posSize <= 4 && b > 4) ERR("please use lastdb5 for " + dbName);
+ if (volumes + 1 == 0) {
+ dump1(dbName, alph.decode, seqCount, fmt != sequenceFormat::fasta);
+ } else {
+ for (unsigned i = 0; i < volumes; ++i) {
+ std::string volName = dbName + stringify(i);
+ std::ifstream f;
+ openOrDie(f, volName + ".prj");
+ seqCount = -1;
+ while (getline(f, line)) {
+ std::istringstream iss(line);
+ getline(iss, word, '=');
+ if (word == "numofsequences") iss >> seqCount;
+ }
+ dump1(volName, alph.decode, seqCount, fmt != sequenceFormat::fasta);
+ }
+ }
+}
+
void lastdb( int argc, char** argv ){
LastdbArguments args;
args.fromArgs( argc, argv );
+ if (args.isDump) return dump(args.lastdbName);
std::string seedText;
if( !args.subsetSeedFile.empty() ){
=====================================
src/makefile
=====================================
@@ -143,7 +143,7 @@ ScoreMatrixData.hh: ../data/*.mat
../build/mat-inc.sh ../data/*.mat > $@
VERSION1 = git describe --dirty
-VERSION2 = echo ' (HEAD -> main, tag: 1250) ' | sed -e 's/.*tag: *//' -e 's/[,) ].*//'
+VERSION2 = echo ' (HEAD -> main, tag: 1254) ' | sed -e 's/.*tag: *//' -e 's/[,) ].*//'
VERSION = \"`test -e ../.git && $(VERSION1) || $(VERSION2)`\"
=====================================
test/last-test.out
=====================================
@@ -141,6 +141,10 @@ p ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
# Query sequences=2
+>chrM
+AATTTTATTTTTTAACCTAACTCCCCTACTAAGTGTACCCCCCCTTTCCCCAGGGGGGGTATACTATGCATAATCGTGCATACATTTATATACCACATATATTATGGTACCGGTAATATATACTATATATGTACTAAACCCATTATATGTATACGGGCATTAACCTATATTCCACATTTCTCCCAATGTCCATTCTATGCATGATCTAGGACATACTCATTTACCCTCCCCATAGACAGTTCCAAACCACTATCAAGCCACCTAACTATGAATGGTTACAGGACATAAATCTCACTCTCATGTTCTCCCCCCAACAAGTCACCTAACTATGAATGGTTACAGGACATACATTTAACTACCATGTTCTAACCCATTTGGTTATGCTCGCCGTATCAGATGGATTTATTGATCGTCCACCTCACGAGAGATCAGCAACCCCTGCCTGTAATGTACTTCATGACCAGTCTCAGGCCCATTCTTTCCCCCTACACCCCTCGCCCTACTTGCCTTCCACCGTACCTCTGGTTCCTCGGTCAGGCACATCCCATGCATAACTCCTGAACTTTCTCACTTTTCACGAAGTCATCTGTGGATTATCTTCCCCTCTTTAGTCCGTGATCGCGGCATCTTCTCTCTTCTATTGCTGTTGGTTCCTTCTCTTTTTGGGGCTTCTTCACAGGTTACCCTTCACAGTGCGGGTGCGAGTGCTATTCAAGTGAAGCCTGGACTACACCTGCGTTGCGTCCTATCCTAGTCCTCTCGTGTCCCTCGATGAGACGGTTTGCGTGTATGGGGAATCATCTTGACACTGATGCACTTTGGATCGCATTTGGTTATGGTTCTTCCACCCCCCCGGTAAATGGTGCTATTTAGTGAATGCTTGTCGGACATATTTTTATCAATTTTCACTTCCTCTATTTTCTTCACAAAACTAGGAAATTCACCACAAttttttctttgttattttttaattttttttttattttttAAAAACATTTTTTAAAAAACTAAATTACATACAAACTACCGCATAAAATCCCTCAAACTATACAAACGTTTATCGTATAATATATATACATTATTGTTTATTCTATCATTATTAGAGAAACTCCACTACCAAAACCATCATTAAAACAAAAATTTACATGCCACTTAACTCCCCTCACAAACAATCGTTATTTATATTGTTAATTAGCAAACACAAAACCCGCCTTCTACCACTATAAAGCCCCCATAGCTTAACCCACAAAGCATGGCACTGAAGATGCCAAGATGGTACCTACTATACCTGTGGGCAAAAGACTTAGTCCTAACCTTTCTATTGGTTTTTGCTAGACATATACATGCAAGTATCCGCATCCCAGTGAAAATGCCCCCAAACCTTTCTTCCCAAGCAAAAGGAGCAGGTATCAGGCACACTCAGCAGTAGCCCAAGACGCCTTGCTTAAGCCACACCCCCACGGGTACTCAGCAGTAATTAACCTTAAGCAATAAGTGTAAACTTGACTTAGCCATAGCAACCCAGGGTTGGTAAATCTTGTGCCAGCCACCGCGGTCATACAAGAAACCCAAATCAATAGCTACCCGGCGTAAAGAGTGGCCACATGTTATCTGCACCAGCTAAGATTAAAATGCAACCAAGCTGTCATAAGCCTAAGATCCACCTAAACCCAACCCAAATCCATCTTAGCCTCAACGATTAATTTTAACCCACGAAAGCTAGGACCCAAACTGGGATTAGATACCCCACTATGCCTAGCCCTAAATCTAGATACCTCCCATCACACATGTATCCGCCTGAGAACTACGAGCACAAACGCTTAAAACTCTAAGGACTTGGCGGTGCCCCAAACCCACCTAGAGGAGCCTGTTCTATAATCGATAATCCACGATTCACCCAACCACCCCTTGCCAGCACAGCCTACATACCGCCGTCGCCAGCCCACCTCTAATGAAAGAACAACAGTGAGCTCAATAGCCCCTCGCTAATAAGACAGGTCAAGGTATAGCCTATGGGGTGGGAGAAATGGGCTACATTTTCTAACATAGAACAAACGAAAAAGGATGTGAAACCCGCCCTTAGAAGGAGGATTTAGCAGTAAAGTGAGATCATACCCCCTAAGCTCACTTTAAGACGGCTCTGAGGCACGTACATACCGCCCGTCACCCTCTTCACAAGCCATCAACATCAATAAATATATACTTCCCCTCCCGGCTAAAGACGAGGCAAGTCGTAACAAGGTAAGTGTACCGGAAGGTGCACTTAGACTACCAAGGCGTAGCTATAACTTCAAAGCATTCAGCTTACACCTGAAAGATACCCTCAACAGACAAGGTCGCCTTGACTTGCCCCCCCTCTAGCCCGACAAACTCGTACCCTTAACATAAAAAACTTACCTCCCCCTCTTAACCAAAACATTATAAATTGTCCCAGTATAGGCGATAGAAAAGACTACCCCGGCGCAATAGAGGCTAACTGTACCGCAAGGGAAAGATGAAATAGCAATGAAAACCATAAGCAAAAAACAGCAAAGACCAACCCTTGTACCTTTTGCATCATGATTTAGCAAGAACAACCAAGCAAAGTGAGCTAAAGTTTGCCTTCCCGAAACCCAAGCGAGCTACTTGCGAGCAGCTAAAATTTGAGCGAACCCGTCTCTGTTGCAAAAGAGCGGGATGACTTGCCAGTAGAGGTGAAAAGCCTACCGAGCTGGGTGATAGCTGGTTACCTGTCAAACGAATCTAAGTTCCCCCTTAACCCACCCCCTAAAGACACCCACCTTTGTCAACCTTGAGAACGTTGGGGTTAAGAGCAATTCGATGGGGGTACAGCTCCATCGAAAAAGAACACAACCTCCTCCAGCGGATAATAATCACCCCTCCCCGCACTGTGGGCCTTCAAGCAGCCACCAACAAAAGAGTGCGTCAAAGCTCCCTCATTAAAAAATCTAAAACCCTATTTGACTCCCTCAACCAAAGCAGGTTAACCTATGACAATAGAAGAATCAATGCTAAAATGAGTAATCTGGAACCTATCCTCCTACGGCGTAAACTTACATTAATACATTATTAACAGAACTCAACTTATACCCCCACACTAACAAGCAATACGTATTCCTCAATCTGTTAAGCCAACCCAGGAGCGCCCACAGGATGATTAAAACCTACAGAAGGAACTCGGCAAACCAAAGACCCGACTGTTTCCCAAAAACATAGCCTTCAGCTAACAACAAGTATTGAAGGTGATGCCTGCCCAGTGACCCCCAAAGTTCAACGGCCGCGGTATCCTAACCGTGCGAAGGTAGCGCAATCAATTGTCCCGTAAATTGAGACTTGTATGAATGGCTAAACGAGGTCTTAACTGTCTCCTGTAGGTAATCTATGAAATTAGTATTCCCGTGCAAAAACGAGAATGTGAACATAAGACGAGAAGACCCTGTGGAACTTTAAAATCACGACCACCTTACAACCTTACACAGCCCCACTGGGTCCACCCACACATAAACCCCTGGTCGACATTTTTCGGTTGGGGCGACCTTGGAGAAAAAAAAATCCTCCAAACCCACAGACCACAACTCTTCACTAAGACCAACTCCTCAAAGTACCAACAGTAACCAGACCCAATATAATTGAGCAATGGACCAAGCTACCCCAGGGATAACAGCGCAATCTCCTCCAAGAGCCCATATCGACAAGGAGGTTTACGACCTCGATGTTGGATCAGGACAACCTAATGGTGCAACCGCTATTAAGGGTTCGTTTGTTCAACGATTAACAGTCCTACGTGATCTGAGTTCAGACCGGAGCAATCCAGGTCGGTTTCTATCTATGGACACTCCTCCTAGTACGAAAGGACCGGAGAAGTGGGGTCAATACCACTGAGCACACCCCAACCTTCTAAGCAATGAATACAACTCAACTGCCAAGAACCCCTCCCCCACACCCGAACTCCTAGAAAAGGATCCAGCTAGCGTGGCAGAGCTCGGCAAATGCAAAAGGCTTAAGCCCTTTATCCAGAGGTTCAAATCCTCTCCCTAGCTACCCCGGACATGACCCTGCCCACCCTAACAAACCTTCTAATCATAACCTTATCCTATATTCTCCCCATCCTAATCGCCGTGGCCTTCTTAACACTTGTAGAACGAAAAATCCTAAGCTACATGCAGGCCCGAAAGGGCCCAAACATTGTGGGCCCTTTTGGTCTACTCCAACCCGTTGCAGACGGGGTAAAACTATTCATTAAAGAGCCAATCCGACCATCTACCTCCTCCCCCTTCCTCTTCATTATTACTCCAATCCTAGCACTACTCCTAGCCCTGACTATTTGAGTCCCCCTCCCACTACCATTCCCCCTTGCAGACCTCAACCTAGGACTACTATTTCTCCTAGCCATATCAAGCCTAACTGTCTACTCTCTACTCTGATCCGGATGAGCATCAAACTCCAAGTATGCCCTAATCGGAGCCCTTCGAGCCGTCGCACAAACAATCTCATACGAAGTCACCCTAGCCATCATCCTGTTATCCACAATCATACTGAGCGGCAATTACACCTTAAGCACCCTGGCCATCACCCAAGAGCCCATCTACCTCATTTTTTCCGCATGACCCCTCGCAATAATATGATACATCTCTACCCTTGCTGAAACCAACCGCGCCCCATTTGACCTAACAGAAGGAGAGTCAGAGCTAGTCTCAGGATTTAATGTAGAATATGCCGCCGGACCATTCGCCATATTCTTCTTAGCCGAATACGCCAACATTATACTAATAAACACACTAACCACCGTCCTATTCCTGAACCCAAGCTTCCTAAATCTCCCACCAGAATTATTTCCCATTGCACTCGCTACAAAAACCCTCCTCCTTTCATCCTCATTTCTATGAATCCGGGCCTCATATCCACGGTTCCGCTATGACCAACTAATACATCTTCTATGAAAAAACTTCCTCCCCCTAACCCTAGCCTTATGCCTCTGACATACCAGCATACCAATCAGCTACGCCGGCCTCCCCCCAATCTAAGGAAGCGTGCCTGAACAAAAAGGATCACTATGATAAAGTGAACATAGAGGTATAACAACCCTCTCACTTCCTTAATCCTAGAAAAGTAGGAATCGAACCTACACAGAAGAGATCAAAACTCTTCATACTCCCTCTATATTATTTTCTAGTAAGGTCAGCTAACTAAGCTATCGGGCCCATACCCCGAAAATGATGGTTTAACCCCTTCCCCTACTAATGAACCCCCATGCAAAACTAATCTGCACAGTAAGCCTCATCATGGGAACCAGCATCACAATCTCCAGCAACCATTGAATCTTAGCCTGAACAGGCTTAGAGATCAACACCTTAGCCATCATCCCCCTCATCTCCAAGTCACACCACCCCCGAGCGATTGAAGCCACTATCAAATATTTCCTCACCCAATCAACTGCATCAGCCCTAATCCTCTTCTCGAGCATAACCAACGCCTGATCCACCGGACAATGAGACATTACACAACTAAACCACCCGACATCATGCCTAATATTAACAATAGCAATCGCAATCAAATTAGGACTAGTCCCATTCCACTTCTGATTCCCAGAAGTACTCCAAGGCTCCTCCCTAATCACTGCCCTACTACTCTCCACCCTAATAAAACTCCCCCCAATCACACTCCTCCTCCTAACATCACAGTCTCTTAATACCACCTTACTCACCCTCCTAGCAATCTCCTCCACCCTAATCGGAGGCTGAATGGGCCTAAACCAAACACAAACACGAAAAATCCTAGCCTTCTCATCCATCTCCCATTTAGGATGAATAATTATAATTATCTCCTATAACCCACAACTCACTATTCTCACCTTCATCCTCTACACAATTATGACCTCAACTGTATTCCTATCCCTAGCCCAAATCAAAGTCCTAAAACTGTCAACACTACTCATCTCATGAACTAAAACCCCAATACTAAATGCAACTGTAATACTAACCCTCCTCTCCCTAGCTGGCCTCCCACCATTAACCGGCTTCATGCCAAAATGACTCATTATCCAAGAACTAACCAAACAAGAAATAACCCCAATAGCCACAATCATCACAATACTATCACTCCTAAGCCTATTCTTCTACCTCCGACTTGCATACCACTCAACAATCACACTCCCCCCCAACTCATCAAACCACATAAAACTCTGACGAACTAACAAAACCCTAAACACCCCCACCGCCATTCTAACTGCGCTATCAACCACCCTATTGCCCCTTTCCCCCCTAATTATTACCATACTATAGAAACTTAGGATTAACTGTCACCAAACCAAAGGCCTTCAAAGCCTTAAATAAGAGTTAAACTCTCTTAGTTTCTGCCCAACTAAGACCAACAGGACATTAACCTGTATCTCCTGAATGCAAATCAGACGCTTTAATTAAGCTAAGGCCTCTACCTAGACAGATGGGCTTCGATCCCATACAATTTTAGTTAACAGCTAAATGCCAACACCAATTGGCTTCTGCCTACAGACCCCGGCACACTTTAGTGTACATCAACGAGTTTGCAACTCATTATGAACTTCACTACAGAGTCGATAAGAAGAGGAATTGAACCTCTGTAAAAAGGACTACAGCCTAACGCTTCAACACTCAGCCATCTTACCTGTGACCTTCATCAACCGATGATTATTCTCAACCAACCACAAAGACATTGGCACTCTTTACCTAATTTTCGGCACATGGGCGGGCATAGCCGGCACAGCACTTAGCCTTCTAATTCGCGCAGAACTAGGACAGCCCGGAACTCTCTTAGGAGACGATCAAATTTACAATGTAATCGTCACAGCCCATGCTTTCGTCATAATCTTCTTTATAGTTATACCCATCATGATCGGTGGCTTCGGAAACTGACTAGTCCCACTTATAATCGGTGCCCCAGACATAGCATTCCCCCGCATAAATAACATAAGCTTCTGACTCCTCCCTCCCTCCTTCCTTCTCCTACTAGCCTCATCTACCGTAGAAGCTGGGGCCGGCACAGGATGGACAGTTTACCCCCCTTTAGCCGGCAACCTAGCCCACGCTGGCGCATCAGTAGACCTAGCCATCTTTCATTACTTAGCAGGTGTTTCCTCCATTCTAGGAGCCATCAACTTTATCACTACCATCATCAACATAAAACCCCCCGCACTGTCACAATACCAAACACCCCTATTCGTATGATCCGTCCTCATTACTGCCATCCTACTACTCCTCTCCTTACCCGTCCTAGCAGCTGGGATTACCATACTACTTACCGACCGCAACCTTAACACCACATTCTTCGACCCAGCTGGAGGAGGAGACCCAATCCTATACCAACACCTATTCTGATTCTTCGGTCACCCCGAAGTTTACATCCTCATCCTCCCAGGTTTCGGAATAATTTCCCACGTAGTAGCATACTATGCAGGAAAAAAAGAACCATTCGGATACATAGGAATAGTCTGAGCCATACTGTCAATCGGATTCCTTGGCTTCATTGTATGAGCCCACCATATATTCACAGTCCGAATGGACGTAGACACCCGAGCCTACTTTACATCAGCCACAATAATCATCGCCATCCCAACTGGTATTAAAGTCTTCAGCTGACTAGCAACCCTGCACGGAGGAACAATTAAATGAGACCCCCCTATGCTATGAGCCCTAGGATTCATCTTCCTCTTCACTATCGGAGGCCTAACGGGAATCGTCCTTGCTAACTCATCACTAGATATTGCCCTTCATGACACCTACTATGTAGTCGCCCACTTCCACTATGTCCTCTCAATGGGGGCAGTTTTTGCCATTCTAGCAGGATTTACCCACTGATTTCCCCTCTTCACAGGCTTTACCCTACACCCATCATGAACCAAGGCACATTTCGGAGTAATATTTACCGGAGTTAACCTAACCTTTTTCCCCCAACATTTCCTGGGCCTAGCTGGAATACCCCGACGATACTCAGATTACCCAGACGCCTACACACTATGAAACACACTATCCTCAATCGGCTCCTTAATTTCAATAACAGCCGTAATCATACTCATATTCATCGTCTGAGAAGCCTTCTCAGCAAAACGAAAAGTACTCCAACCCGAATTAACTGCCACTAATATCGAATGAATTCATGGCTGCCCACCCCCATACCACACCTTCGAAGAACCAGCCTTTGTACAAGTGCAAGAAAGGAAGGAATCGAACCCTCACATGTTGGTTTCAAGCCAACCGCATCAAACCACTTAATGCTTCTTTCTTATGAGACGTTAGTAAACCAATTACATAGACCTGTCAAGACTAAATCACAGGTGCAAACCCTGTACATCTCATATGGCCAACCACTCCCAACTAGGCTTTCAAGACGCCTCATCCCCCATCATAGAAGAGCTCGTTGAATTCCACGACCACGCCCTGATAGTCGCACTAGCAATTTGCAGCTTAGTACTCTACCTTCTAACTCTTATACTTATAGAAAAACTATCATCAAACACCGTAGATGCCCAAGAAGTTGAACTAATCTGAACCATCCTACCCGCTATTGTCCTAGTCCTGCTTGCCCTCCCCTCCCTCCAAATCCTCTACATAATAGACGAAATCGACGAACCTGATCTCACCCTAAAAGCCATCGGACACCAATGATACTGAACCTATGAATACACAGACTTCAAGGACCTCTCATTTGACTCCTACATAACCCCAACAACAGACCTCCCCCTAGGCCACTTCCGCCTACTAGAAGTCGACCATCGCATTGTAATCCCCATAGAATCCCCCATTCGAGTAATCATCACCGCTGATGACGTCCTCCACTCATGAGCCGTACCCGCCCTCGGGGTAAAAACAGACGCAATCCCTGGACGACTAAATCAAACCTCCTTCATCACCACTCGACCAGGAGTGTTTTACGGACAATGCTCAGAAATCTGCGGAGCTAACCACAGCTACATACCCATTGTAGTAGAGTCTACCCCCCTAAAACACTTTGAAGCCTGATCCTCACTACTGTCATCTTAACCATTAAGAAGCTATGCACCAGCACTAGCCTTTTAAGCTAGAGAGAGGGGACACCCTCCCCCTTAATGACATGCCCCAATTAAACCCAAACCCATGATTCTCCATCATACTCCTAACTTGATTCACCTTCTCTCTGCTTATCCAACCCAAACTTCTTTCATTCACTCTAACAAACAACCCTGCAAACAAAATTACAACAACTAAACCCACCCCCTGAACCTGACCATGAACCTAAGCTTCTTCGACCAATTCTCAAGCCCCTGCCTACTAGGAATCCCTCTAATCCTCCCATCACTCCTTCTTCCAGCCCTCCTACTTCCATCACCAGGAAACCGATGGATCAACAACCGCCTCTCCACCATCCAACTCTGATTCACCCACCTAATCACAAAACAACTAATAACCCCCCTAAACAAGGCAGGTCACAAATGAGCCCTCCTACTCACCTCACTTATCCTAATACTCCTCTCCATTAACCTCCTAGGCCTCCTCCCCTACACCTTCACCCCAACTACCCAACTATCAATAAACATGGCCTTAGCCCTGCCACTATGACTAGCCACCTTACTAACAGGCCTGCGAAACCAACCCTCCGCCTCCTTAGGACACCTACTCCCTGAAGGCACCCCCACCCCACTGATTCCAGCCCTAATCATAATCGAAACAACCAGCCTACTTATTCGGCCATTAGCCCTAGGAGTACGCCTAACAGCAAACCTCACAGCTGGTCACCTACTTATCCAACTTATCTCTACAGCCACAATCGCCCTACTACCAATAATGCCATCAATCTCCGCCCTAACGGCACTCATCCTATTCCTACTAACCATCCTAGAAGTGGCAGTAGCAATAATCCAAGCCTACGTCTTCGTCCTCCTCCTAAGCCTCTACTTACAAGAAAATATTTAATGGCACACCAAGCACACTCCTACCACATAGTTGACCCAAGCCCATGACCAATCTTCGGCGCAGCCGCAGCACTACTAACCACCTCTGGCCTAATCATATGGTTCCACTACAGCTCGACCACCCTACTGACAATAGGCCTCCTCTCTATACTTCTAGTCATGCTGCAATGATGACGAGACGTAGTCCGAGAAAGCACCTTCCAGGGCCACCACACCCCAACTGTCCAAAAGGGCCTACGATACGGAATAATCCTTTTCATTACATCAGAGGCCTTCTTCTTCCTAGGATTCTTCTGAGCCTTCTTCCACTCAAGCCTAGCCCCAACACCAGAACTGGGGGGCCAATGGCCCCCAACAGGAGTCAAACCCCTAAACCCCCTTGAAGTACCCCTACTAAATACAGCAATCCTCCTAGCCTCAGGAGTCACCGTTACATGGGCTCACCACAGCATCACAGAAGGAAACCGAAAACAAGCCATCCACGCACTAACTCTCACAATCCTCCTAGGATTCTATTTCACAGCCCTACAAGCAATAGAGTACCATGAAGCCTCCTTCTCAATCGCTGACAGCGTCTACGGCTCCACCTTCTTCGTCGCTACAGGGTTCCACGGACTACATGTAATCATTGGATCATCCTTTTTAACAGTTTGCCTCCTACGACTAATCAAATTCCACTTCACACCAAACCACCACTTCGGATTTGAAGCAGCAGCCTGATACTGACACTTCGTAGACATCATCTGACTCTTCCTCTACATATCCATATACTGATGAGGATCTTGCTCTTCTAGTATACTCATTACAACTGACTTCCAATCTTTAAAATCTGGTATCAACCCAGAGAAGAGCAATGAACACACTTACATTTATACTCTCACTATCCTTTCTACTAAGCGCTGCACTAACTACTATAAACTTTTGACTAGCCCAAATAGCCCCAGACACAGAAAAACTGTCACCGTACGAATGCGGATTTGACCCACTAGGATCAGCCCGACTCCCATTCTCAATCCGATTCTTCCTAGTAGCCATCCTATTCCTTTTATTCGACCTAGAAATCGCCCTGCTTCTTCCCCTTCCATGAGCCATCCAACTTGCACACCCTATAATAACCCTTACTTGAGCCACCACTATCATCGCCCTCCTCACATTTGGTCTCATCTACGAATGAACTCAGGGCGGCTTAGAATGAGCAGAATAACAGAAAGTTAGTCTAACTAAGACAGCTGGTTTCGACCCAGCAAATTATAGACCCACCTATAACTTTCTTATGTCTCCCCTACACTTCAGCTTCTATTCTGCATTCACATTCAGCAGCCTAGGACTAGCATTCCACCGAACACACCTCATCTCTGCCCTACTATGCCTAGAGAGCATAATACTATCCATATTCATCCCCCTCTCAATCTGACCAGTAGAAAACCAAACCCCATCATTCGCCCTTGTACCTATCCTAATACTAGCCTTCTCAGCATGCGAAGCTGGCACAGGCCTAGCCATACTAGTAGCTTCTGCACGAACACATGGCTCTGACCACCTACACAACCTAAACCTTCTACAATGCTAAAGATCATCCTACCAACAATCATACTCTTGCCCACAGCCCTCTTATCCCCAGCAAAATCCATATGAACTAACACCACAATATACAGCCTTCTAATCGCCTCGATCAGCCTACACTGACTAACCCCATCATACTACCCCACAAAAACCCTAACCCTCTGAACAGGCATAGACCAAATCTCAACTCCCCTCTTAGTACTCTCCTGCTGGTTTCTCCCCCTCATAATTATAGCTAGCCAAGGCCACCTACAACATGAACCCCACAAACGAAAACGAATATTCATCTCCACCTTAATCATCATCCAACCATTCATCATCCTAGCCTTCTCAGCAACTGAACTCATACTATTCTACATCTCATTCGAAGCAACCCTAATCCCAACCCTCATCTTAATCACACGCTGAGGAAACCAACCAGAACGACTTAGCGCAGGCATTTACCTTCTATTCTATACCCTAATTAGCTCTCTTCCCCTACTAGTCTCCATCCTCTACCTTCACACAAATACTGGAACCCTCCACCTACCCATTATCAAACTCACCCACCCCAACCTACCTGCCTCCTGAACAAGCTTATTATCTAGCCTAGCTCTCCTAATAGCCTTTATAGTCAAAGCACCCCTATACGGACTACACCTATGACTGCCTAAAGCCCATGTAGAAGCACCAATCGCAGGCTCCATACTACTCGCTGCTCTACTACTAAAACTAGGCGGATATGGCATCATACGAGTCACCCTCCTAATGGAGCCCGTATCCAACTTCTTACACTACCCCTTCCTCACCCTAGCCCTATGAGGTGCCCTAATAACTAGCTCTATCTGCTTACGCCAAACAGACCTAAAATCCCTCATTGCCTACTCATCCGTAAGCCATATGGGCCTAGTCATCGCTGCAAGTATAATCCAAACCCAATGATCATTCTCAGGTGCAATAATCCTCATAATCTCCCATGGACTAACCTCTTCCCTTTTATTCTGCCTAGCAAACACAAACTACGAACGGACACACAGCCGCATTCTTATCCTGACACGAGGCCTCCAACCCCTCCTACCATTGATATCAGTATGATGATTACTAGCCAACTTAACCAACATGGCCCTGCCCCCAACCACCAACCTGATAGCAGAACTAACAATTATAGTTGCCCTCTTCAACTGATCCTCCCCCACAATTATCTTAACCGGCACTGCAACACTCCTAACCGCCTCTTACACCCTCTACATACTACTCTCAACCCAACGAGGCACTCTTCCATCCCACATCACAACAACCCCCAACTCAAACACTCGAGAACATCTTCTCATAACCCTCCACATCATCCCCATACTAACACTCATCCTCAAACCAGAACTAATCTCAGGAACCCCTCTATGCAAACATAGTTTAACCCAAACATTAGATTGTGATTCTAAAAATAGGAGTTTAACCCTCCTTGTTCGCCGAGGGGAGGCCCAAGCCAGCAAGAACTGCTAATTCCTGCATCTGAGCTTTAAACCTCAGTCCCCTTAACTTTTAAAGGATAAGAGCAATCCGTTGGTCTTAGGAACCACCTATCTTGGTGCAAATCCAAGTAAAAGTAATGGAGACTCCACTGCTCCTTAACACCCTCACAACATTAACACTACTCACCCTCCTTACCCCTATTATCCTTCCCCCCCTCCTAAATCTAAAAAACTCCCCCATATCCATCACCAAAACCATTAAAACCGCCTTCCTAATCAGCCTAATCCCAACAACAATCTTCATCCACTCAGGGGCAGAAAGCATTGCCACCCACTGAGAATGACAATTTATCCCCAACTTCAAGATCCCCATCTCCCTAAAAATAGACATATACTCCATAATATTCTTCCCCATTGCACTATTTGTAACCTGATCCATCTTAGAGTTCGCAACATGATACATAGCATCCGAACCATTTATTACAAAATTCTTTACCTACCTACTCACCTTCCTCATCGCCATATTAACACTAACCATCGCAAATAACATATTCCTCCTATTTGTAGGATGAGAAGGAGTAGGAATCATGTCATTCCTTCTCATTGGATGATGACAAGGACGAGCTGAAGCCAACACAGCTGCACTACAGGCAATAATCTACAACCGAATCGGAGACATTGGCCTCATCCTAAGCATAGCATGACTAGCCTCTTCCCTAAACACCTGAGAAATTCAACAAATCACCCACCCAAACCAAACACCCACCCTCCCCCTCCTTGGCCTAATCCTAGCCGCCACAGGAAAATCCGCTCAATTTGGCCTTCACCCATGACTTCCAGCAGCAATAGAAGGCCCAACCCCTGTCTCCGCCCTACTCCATTCCAGCACAATAGTAGTTGCTGGAATTTTTTTACTCATCCGCACCCACCCCTTCCTGTCATCCAATAAAACAGCCCTGACAACGTGCCTATGCTTAGGTGCTCTATCAACACTCTTTGCCGCAACATGCGCTCTCACTCAAAACGACATCAAAAAAATCATTGCCTTCTCCACTTCAAGCCAACTAGGCCTCATAATAGTCACAATTGGCCTAGACCTCCCCCAACTAGCCTTCCTCCACATCTCAACCCATGCCTTCTTTAAAGCTATATTATTCCTATGCTCCGGCCTAATTATCCACAGCCTCAATGGAGAACAAGACATCCGCAAAATAGGATGTCTACAAAAAACCCTCCCAATAACCACCTCCTGCCTAACCATTGGCAACCTCGCTCTAATAGGAACTCCATTCCTAGCAGGCTTCTACTCAAAAGACCTGATCATCGAAAACCTAAACACCTCATACATCAATACCTGAGCCCTCTCACTTACACTACTTGCCACATCTTTCACTGCAACCTACAGCCTCCGCATAACCTTACTAGTCCAAACAGGACACACACGAACCCCCAGCAATCACCCCATTAACGAAAACACCCCCCCAGCCATTCTCCCAATCATACGACTAGCCCTTGGCAGCATTATAGCAGGCCTATTAATCTCATCCCTAATCCTCCCCCCTAAAACCCCTCCAATAACTATACCCACCATCACAAAAACTGCTGCCATCATTGTTACAACCCTAGGAATTATCCTAGCCCTAGAACTCTCAAGCCTATCATACTCCCTCACTCCCCCAAAACACAATCCCCTCATAAACTTCTCCTCCTCCCTAGGCTACTTTAACCCCCTAACTCACCGAATTAGCCCCTCAATCCTCCTACATACCGGACAAAAAATTGCATCCCACTTAATCGACATAGCATGGTACAAAAAAATAGGCCCCGAAGGCCTTGCCAACCTTCATCTCACCATAACCAAAATCTCAACCACACTCCACACAGGCCTAATTAAATCTTACCTGGGTTCCTTCGCCCTCACAATCCTTACAACGATCCTACTTATCCAAAAATAAACTAATGGCACCCAACATTCGAAAATCCCACCCCCTACTAAAAATAATTAACAACTCCCTAATCGACCTCCCAGCCCCATCCAACATCTCTGCTTGATGAAATTTCGGCTCCCTATTAGCAGTCTGCCTCATGACCCAAATCCTCACCGGCCTACTACTAGCCATGCACTACACAGCAGACACATCCCTAGCCTTCTCCTCCGTAGCCCACACTTGCCGGAACGTACAATACGGCTGACTCATCCGGAATCTCCACGCAAACGGCGCCTCATTCTTCTTCATCTGTATCTTCCTTCACATCGGACGAGGCCTATACTACGGCTCCTACCTCTACAAGGAAACCTGAAACACAGGAGTAATCCTCCTCCTCACACTCATAGCCACCGCCTTTGTGGGCTATGTTCTCCCATGGGGCCAAATATCATTCTGAGGGGCCACCGTTATCACAAACCTATTCTCAGCAATTCCCTACATTGGACACACCCTAGTAGAGTGAGCCTGAGGGGGATTTTCAGTCGACAACCCAACCCTTACCCGATTCTTCGCTTTACACTTCCTCCTCCCCTTTGCAATCGCAGGTATTACTATCATCCACCTCACCTTCCTACACGAATCAGGCTCAAACAACCCCCTAGGCATCTCATCCGACTCTGACAAAATTCCATTTCACCCATACTACTCCTTCAAAGACATTCTGGGCTTAACTCTCATACTCACCCCATTCCTAACACTAGCCCTATTCTCCCCCAACCTCCTAGGAGACCCAGAAAACTTCACCCCAGCAAACCCACTAGTAACCCCCCCACATATCAAACCAGAATGATATTTTCTATTCGCCTATGCCATCCTACGCTCCATCCCCAACAAACTTGGAGGTGTACTAGCCCTAGCAGCCTCAGTCCTCATCCTCTTCCTAATCCCCTTCCTCCACAAATCTAAACAACGAACAATAACCTTCCGACCACTCTCCCAAACCCTATTCTGACTTCTAGTAGCCAACCTTCTTATCCTAACCTGAATCGGAAGCCAACCAGTAGAACACCCCTTCATCATCATTGGCCAAATAGCATCCCTCTCTTACTTCACCATCCTACTTATCCTCTTCCCCACAATCGGAACACTAGAAAACAAAATACTCAACTACTAAAATACTCTAATAGTTTATGAAAAACATTGGTCTTGTAAACCAAAAACTGAAGACTCCACCCTTCTTAGAGTATCAGAAAAGGAGGGCTCAAACCTCCATCTCCAGCTCCCAAAGCTGGTATTTTCAAATAAACTACTCTCTGAAACCCTTAAACCGCCCGAATTGCCCCCCGAGACAACCCACGCACAAGCTCTAGTACAACAAACAAAGCTAACAACAAACCTCACCCAGCCACCAAAAACAACCCAACCCCACATGAATAAAACACCGCAACTCCACTAAAATCCAACCGAGCAAAAGACACACCCCCGCCATCAACAGTAACCACCCCCACCTTTCAAAAATCAACGAGCCCTCCCAGAACCACCCCCATTCAAACCACCAAGACAAAACCTAGCCCATACCCCACCACCCGCCAATCCCCCCAAGCCTCAGGATAAGGATCCGCAGCTAATGACACAGAATAAACAAAAACCACCAACATCCCCCCTAAATACACCAAAAATAACGCCAAGGAAACAAAAGAAACACCCAAACTCACTAACCACCCACATCCTATCACAGACGCTACCACCAACCCCACCACCCCATAATACGGCGAAGGATTAGACGCCACAGCTAAAACCCCCAGCATAAAACAAATCCCAAGAAAAATCACAAAATAAGTCATATTATTCCCGCTTGGTTAGACCCCAAGGACTACGGCTTGAAAAGCCATTGTTGTTCTCAACTACGGGAAC
+>chr32
+CATCTAAACCAACACCTAATCCTAAACCTAAGGCCTTCCGGAATCCTAAACCTAAGCCAACAGctaaccctaacccatcccctaacccaatccatagccctaagcttaagcctaaccctaagccaaaccctagccctaaccatagccccaactccagcactaaccgtaatggtaaacttaatgataatcctaaccctaacacaaaccctTCTTTCCGGAGCTGGGGAAACCGACTCCAGAAATGCCATCTGAGGGAACAGACGTCCTGGCAGATAGAACAAACCAGGTGTGAGCACTGTCTTTCCAAAGTTACACCGAAGCCGTTGGAGGACAGGTCGGACCTCAGGCCTTCCCGCGGCACCAACTACTGTCGGCGGATTTGCGCATAGATCCTTCACAGCTGTTTCAAAGAACCATTCTGTGATTCTATGATCTTCCAGGACCCTTCCAAGCCACACCATCCTGTGGTTCTatcatcttccaggactcttgcaacacaaaccattctatggttctgtgatCACTAAGGAACCTCCCAAGCCACGCCGTCCTGCAGTTCTGtgatcttccaggacccttccaacacggaccatcctatggttctatgatCTTCCAGGACCCTCCTGTGCGGGTGATGTCACCATGACGTGATGACCTCACAGATGCCCTGGGGTGGGGCAGGGGCAGTGGGTCAGCGCGGAACCTGCTGGCCCCATTCTGCGGGTGGTGCTGGTCCAGCGAGGAGCTGTGCGAGTGGTGCAGTAATGCGGGCCCAGTGTGTCAGCAGAAGATTAAGGGCGGTGTGGCGTGCGAAGCTGGTGGAGGAGGAGCTGCTGGTGAGCTCTGGGTGCACAGACACAGAAGGGCCGGCGGGGGGAGCTGCCGGCTGGAGGCAGCAGAGGGCCGGGCACCTCCGGTGGGATGCAGAGCTGCCGGCAGCACCTCGGTGCCAACGCTGCTCCTCTCCCTTCACACAGGCTCATGCGGCCGTGGAGAAGTGCAAGGCCGTGGCCAGGGAATCCTTGATG
TEST lastal -fTAB -i1 -w0 -e40 /tmp/last-test galGal3-M-32.fa
#
# a=7 b=1 A=7 B=1 e=40 d=-1 x=39 y=9 z=39 D=1e+06 E=1.13155e+07
@@ -1985,6 +1989,406 @@ q channel_100_read_89_2 +)*+*'()')(''*()((()*+-()&'('''*''(
# batch 1
# Query sequences=2
+ at S1_1
+TAAATCCATAAGTATTACTCGGCAGAAGAGGTTTGATGTCGGCGAGCTGTTTCTCCAGCCCGGCAATACGCTGTTGTAGTTGCCAACGGGGAGTCATGGTTTTGCATTCCCCATCCCCGCTCCGGGCGGTAAAGCGTGGCCAAATCCACAAAAATGGCCAGATAACATGCAGCGTAAAAAGATCACCCAACCAGCAACATGAATGGCGTCGGCATGGGATGATTACGTTTTTTAGCATCAGGTAGGGAATATCATTAAAATAATAATCCCATAGAATATCACCAGAAATACAAAAATAAGCACTCCCAGTGCAAAATAATCCAGAAACATATTTCCCTCAGAGATATAAAAAAGAACAATTAACGCATATTATGAAATCCCATGATGCAGTGCAATTTCCTTATTTATATAACGGCATATTGTTTTTTATATACTTTCTGAAGTGTGCTGCGTGGCTTTTCAACGGTCGAGGTTTATCATATTGAAATAATGGAACTATTGACCAAGCTAATGAATAACTCCAGTAAAACATCCACAGTACAGTAAAGCGTATTAAACCTTCAATTATCTACCGTTTATTGCTGATTGGCCTCGGAACGCCAATGGTGATTTACGGCTGGTTTGCCCGCTCACCATCGAAACGCGAGAGTAAACTCCTGGCAAAACACGCCCCAGAAACGCATTCTGTTGGCGTAGTCTGGGTTATTGCGCACGTAGGTTTAAAACGTAAATTGTAACAACGT
++
+vnY~KZymvU~{)bPl~msb~~~yMl~iD\~~{BktN~Gs~~T~YfV~~~P[w~~~T~?]~~A]~^~HY~~Wn~Vw'oc~PbEu_~cbeV~JGxX~/7~D~U`R3ex3~?r~igtyG~=q at vk~Tr~:vrJAvoZy~~eo~~Z?V~jakp~^M:FQw~U3YOE~lO\X~q~l_~_d{~u~eJCaOQa~~e~3y~~M~~T~dFbs~~4lfxg~~\C~pj_j~0Y_~7o~~~_D~q~[J~~uIEY~faU~}yYb{apcdF~E~W~O~~m.NMaE>~tY~~FqlP~~t[L~SA~~J~~.LS~^OPT9~~]s~gLTf~*=;M{>U_~b at jPTl~a~~zogk~=2JR;u~<f~SF~jVc~G~}Lfgp~S'k~WO~Y]~^~kc~@{C~~IHxV~ZeZq~=~~]XAp~L~cnQ~~P~aAV\RN~W:B~IdYPTD\[~~NI_u~`Zds~~f~~gI~~OuVF;sDAgfOeI_^Y~;~~U>n~Yi~~c_Z`~^k~~v~P~~d~:~Xsx~S}~ppI>O~Ur~{\L~~~]b~P@\~~~Vjo;lS|Crs~~XPICyV:tR~~c~~k~~b~~~S~RhT[~~Vw~To~~~~W~s/Vf~oQy~Gaf^~}vS~gC~~~Cdv';h<~@?LZ~~nRhew~~v`Px~}~~[n}o~fuPkjWse_L~~ad~~I~OZ~~=br~m~ZBw~h~X~~|QWvL~2`~~YQ~b~zgJ1F~~do[~~L?q?~~IH~~K~`~R`rb]1~j7.~~RY>RF.X~~~V)~~~~~~
+ at S1_2
+TTGCCTAGTTCCTTCACCCGAGTTCTCTCAAGCGCCTTGGTATTCTCTACCTGACCACCGTGTCGGTTTGGGGTACGATTTTGATGTTACCTGATGCTTAGAGGCTTTTCCTGGAAGCAGGGCATTTGTTGCTCAGCACCGTAGTGCCTCGTCATACGCCTCAGCCTTGATTTGCCGGATTTGCCTGGAAAACCAGCCTACACGCTTAAACCGGGACAACCGTCGCCCGGCCAACATAGCCTTCTCCGTCCCCCCTTCGCAGTAACACCAAGTACAGGAATATTAACCTGTTTCCCATCGACTACGCCTTTCGGCCTCGCCTTAGGGGTCGACTCACCCTGCCCCGATTAACGTTGGACAGGAACCCTGGTCTTCCGGCGAGCGGGCTTTTCACCCGCTTTATCGTTACTTATGTCGCATTCGCACTTCTGGATACCTCCAGCA
++
+X0CXP4b:3COT6P9<GIHR98:D2S9*6'7 at C+;:8G]N/'FJR5=OSjF at 6UnK%GN6G<I/M;Mm8I-LJI>TU,G&)3AG=P:>>>`<*FQP7D/AD44D5Z>>k;?=S6;4vaYK<S>LM4Ug*e at EBc.JTR*30ACa~QAtM=(?D?B9F<6wHyE/:~O0R3H:G06g:Ja=><0YMF2J9LIY)Ew<E/PK9?oWWDSCE0V_P<3D9;ED=E?N.M at zT6K.fI<4ECJ/iX(NE59RU3<EK-JQR-P~IA.bB?0&\P0W%CGE*7L8>?Q-AA7HZ~HDRLBHBF~MLAG-kFH>2=GXMOgE7DD0W3%'7BIK?~@BA>EP;E2A8/<nVHX at C?\>\]?0M?42?cuW<DIo-2O<8AI/@WZ`9Q;4L+IAARfWNaM at SM?974]BGE^(@R<(GHEJJ5B2~@>.L/DY591@@*8?g3PM<//_
+ at S1_3
+CCACCACCACCTTCCGGATTGCCGCACGGCAGCACCGTCGCGGATTGAGCTGACGCCGGGCTATTTTCAGATAACCGCCACGCCGCATCTTGCCGTTTATGACCCGACGGTACAGTTTGAGTTCTGGTTCTCGGAAAAGCGGATTGCGGATATCAGGCAGGTTGAAACCGCAGCCCGCATCTTGGCCGGCGCTGTACTGGATAGCTGCCAGTATCAATATCAAACCGGGCCAGATTATTATTTTTA
++
+~^`s?~XPu~:1~~~fw~ex1jK]h~~}H~V~IeG~GcO~A5~+~mg_E~.GN~U}xJ]o~xY=~d<~x8j~?U~~q~~~~~s@~~~\~~~~Y~oLO`~~de[Wi~~>~~~htF[Y~Bd~~\U>[sSm~~JN`VT~F~~~lUN~_lP^`y~J~~'~ZSOANH<^aY4Y~~1l1~cLWbZf~R``~`V=bUJ_`P~~X~~Xm~s[|~j~~~O~~^~p~;wMY~pi~Y?@~~KMy~WC[~~Y`~~~N~
+ at S1_4
+GGTTGCTGAAACAGGAAGTTTTTCAAAAGGCGGCAGAACCGATTATGTAAACCACGGCGACGATCAGTTATCGCATTAAACTTCTGGAAGAGAATACCGGAGTAGCGCTGTTTTTCCGACGACTCGCAGCGTGACGTTGACAGCGGCGGCGAGCATTCTACTTTCCCGGCCAGAGACTGCTGAGCTGGCTGGAAAGTTGCCAAGCGAGCTGGCAACAGGTGAATGATGGCGTGGAACGCCAGGTGAATATTGTCATCAACAACCTGCTCTACCACCCCCAGGCCGTCGCCCAGTTGCTGGCGTGGCTGAATGAAAGTTACCCCTTTACCCAGTTTCACATCACCCGACAATCTATATGGGCGTCTGGGATTCGCTATTATACGAAGGTTTTTCACGTGCTATCGGCGTTCACGGGAACGAGGCGCTGGCAAA
++
++/=<@&6,2J19+(.09(?/:8O/;(,*%&G,1)(9+(&((3?8%+)(9/3@)@,-&E3'%?83'*6--80<683&-'3120.&.&/0%F2/=4ED:5518069)+)?788**0,4>7.+%+6?>J<6I<2',*==0.91(<86,.+)/6/0A07(02</..27B8A/(6+4>.,29A'2B>-=-%.9C*37@/9=264$8+544,(7*++('C-:-83,+1I2+89:/7;)D:'3&+54=*'-);'2?6;)2(&:?;46>8*<>,9,B.@:4.'()*$'+)4(-6A3<=+8F;@=(%(&9/=.(-=7@=:2%8679C,4)@6(8B-=D1,7,1//<5('1+5>-64'4+&:)&B+$,(-(:.:,;30;%3-533#*2';:2FD4@*G38,&=7=(>/G7;?.00,0%:B=30)?/01/$37//953L&37*
+ at S1_5
+TCCGCCACTTCTCGGCATCCATTAAACGGGTCTGGTCGGTGGATTAACAGCAGATCCAGATGATCGGTCGCGAGATTAATTAGCGACTGTTCGGCGCTCTTAATGATGTGATCGCGGTCAGTGATGTAATGACCAATGACGTTTTCTTCACGCGCGGTCGTCGCGATACCGCATTTACTGACGATTTCCATCCGTTCACGCAGGTGAGGTGCCAGTTTCAGGCCTCGCCAAACGCCGCTTCGCACTGATAGCCACCATAATATCAGCATGGTCCACGGTGGTCACGCCGAGATCCAGATGCTCTTCAATAAAACTGACCAGCTGGCGGGCGGACATATTCCAGTCCATAATCGCCAGTAGCCCATACAAAACGGGAAAACTCGGGCCTTGCGGCGCAATAGTAATACGCTGAACCATAATCACTTCTCTTATCAGATATGAGAGGAGTATACGCAAGATTAGGTTCAAAAGAGTGATGGTTGCTCCGGTTCGTCTGATGACGCTGGCTTATTTCGCGTAATTTGCGCATTAATCGCTGCCGACAAAGGCGCAGCACCT
++
+pxbkUKc~QFem]~uR~~bpqO{~(X~sh|B:BWp\e~6{~h~3as6-Re\rc~\cA~2qp~`dM~~bj~~L?~~hO~UdRv~cbI~j~z~_o3~k~^~9~~~7u~ks~p6~MuL^~~xpgi~~kYY;f-Ccp~f~~~o\Zs~VO~x~wW at Cor~~|~~H~~o[x3XS~~r~QQJO8~~|~~naJQS~OI~~~XYZZup~S~~gI~|N~_xZ~N~Ea~~_~~]r~e~B~T~@~~nCb~>~JiQ~|~+~~~StN_~~~c:{}~kbm~k~~]w~~~{X~eKX~M~IpxCK?~tm~G~7~R~rs`HQS~X~SfGNb~D~Q~~?~YtbcZRMp'n~L|~NTR4if~f~k\ak[Dr2b~QvXfqxRF\aq;t~VaAkEn`v{qH~~jp~g~Vn1~MT~XdZ]7IaQR~[oB~~|~~HIZ1v~?K~~F~fO^p[ai~aj{~~mg~PFrGU~~{r~tU~~P~~]W5~~~~UP~~l~~j~=w~mon~[~K~cI~Fj7~:rh'~~g~~aPi1VG~rfQh~~xt\pIg>~MFnz~LE^}Cn~sp~iSl~S~lKbGk~:~~+~~nru~~
+ at S1_6
+GTACTTCTTCTTCGGCTGCTTACGCAGGCCATTCCACCGATTGTTGTTGCCGCACTTGTTGTAAACGACCACTGGCAGTTAGCGCGGTTTTGAAGTCGATGATGGCGTGCCATGATCTCATCGATTCCACGTTTTTCCAGTGCGCTACAAGTCAGAACCCGTGGCTCCTTCGTCGTATTTACGTCGCAGAATATGCAGGGCACTCTCGTACATATGCCGGGCAATGGCGACATTGTATGGTTATCGCCATCGTCTTTGTGATAATGATCAGATCAGCCACTTCATCAGCCCTTTTTTAATGCCCTGCAGATCATCGCCCGCCACCGGCAATATTGCAACGAGATAAAACAGTCCACCAGCGGGCGACTTCTGTTTCCGACTGCCCGACGCCAACCGTTTCGACAATCACTACGTCATAACCCGCTGCTTGCATAACAGCATTAATTCCCGCGCTCGCTGACTGGCACCGCCCAGATGACCGGAGGATGGTACCGGGCGAATAAACGCCGCTTCGGCACGCGCCAGGGTCCATTCATGCGGGTTTTATCCCCGAAATGCTACCGCCAGTGACCGGGCTGCTGGGTCGACCGCAATAACCGCGACCTTTAATCCCTTCGAATCAACAACATGCCAAAGGCCTCAAGAAAGGTACTTTTCCCCGCGCCGGGGTGCCGGTAACGCCCAGTCGCAGGGTGTTACCGAGTACGGCATAATGGCATCAAGCAGCTGCGTACTTAGTGCCTGAT
++
+M0ICKB8/C8O08^\=G+)G==56/P8'*;BT,:,<&<-26%PC>9B4<2><D7GL2ANI?%4CU8-=731BG+I4cV&[/);L9E1+6AOMAB'?`C%6;2;0JFVID=5K?E1;:9>3]S++*-B(7/MFOJ;2?N%396@;>HMS.P/BJGF::M_D?L;U0K/32D`@=?g$KL<=4,-AL9$GG_<I89F>ENGS*3$?Il*.9>BBB52cB2FPEED'@T?J7I4:'4V8H&=-(B41S_0*E;=:B1<F->?<6I8L'6EJKE<:82 at I14::1NJK)H at D5BC+:><ZI06.:F?G<B)BN<(*79;P.>,;B5&'H=>+CIG('57=:OB572N0 at J)3KDC<=D%4C>L77ANN9E9I@>@RFZAJ60',M2 at 7:@+)A<O<@57Ua13 at E7~XJAG+H71.>5`;8@=Y'N:A/3(.;IEC-3BT7P?+FFG4>30:JC89?5=D>>8<K'-XH4:+CUE:1</E17,$>_O?G935:@33-9E:.+=I?EEG/M]8EAM1+GGMB=-%?NGC3<@8(*CAI9M<G87<VD/';;O?O>@<:7B.52$LJDY- at J@6/:4B);C$K)@3 at -1=XKBG?. at NJ?cON?E?UY0>O8>3:+<=F0b1>-U)5'TA+Rh=aD&;CEY)(=5[+4<J;YnSA<=MjVZ*MX?8C+IJ75M9G/L8R6.8HC59,5GA2ED at 0GU894/D>%?GD:,A24<f;3N>>B.EL86&BGNb$&0>?F5GC9MM.69??4@?M3
+ at S1_7
+CTCCATCTGTAGATAATCCCGTAGAGGACAGACCTGTGAGTAACCCGGCAACGAACGCATCTCCCGCCCCCGTGCTATCGACACAATTCACAGACATTCCAGCAAAATGGTGAACTTGTCCTCGATAACAGACCACCAACCTTCTGCACCCTTTAGTCACCAACAGCATGGCGATCTCATACTCTTTTGCCAGGGCGCATATATCCCGTCGTTCTGTGTTTTTCCACTGATAAGTCGCCATTCTTCTTCCGAGATGCTTACGACATCCGCCAGTTGTAGCGCCTGCCGCAAACACAAGCGGAGCAAATGCTCGTCTTGCCATAGAATCTTCACGAATATTAGGATCGAAGCTGACAAAACCTCCGGCTGCCGGATCGCCGTCATCGCAGTAAATGCGCTGGTACGCGAAGGCTCGGCAGACAACGCAATTGAACAGAGAT
++
+L<;N7M7?><Y1B<?6<>E3,58.=+2TJ?-0>?(9Q9:;79AV8C46DV'72O<2\C.6FH<4J>-F:>.EN40F;:>,N at UA<:IT at V3632''3/HB0;L)C%6+;KE6:/:8?15-C%RO3=S<B2 at IA;95<0N:$,1P4A47I'XZ(MLI853<=JH+G/O2L5,L964/:%=1(U/AJ>RCI.-5=POG at HW:?@G<M?A5?@b->C4LD/==J.56&C',;>%>@6W<K)39BF~CQ4%A:>*3BM&0?@I=A7g0AU.;iN7.A77&*8A=L23f*4DA8=AU7ABT(5O?.1E4&>5,M:@2A71D@:I;:QNE&=B*5>.;3K05N<9FL=U[IC/M(<J<9DC:D6[Y8,9*<?M7>3)N2>K>0dOF<ED798E@/D>%6:+GWV*]DCL:01;L17+.%H<P-D=IN>J0Q:;9N>8*DE=9PQFA
+ at S1_8
+TGACCATAGATTAATACCTGAAGCGACTGAAGCCCAAACCTGAGGGTCTTTAGTGGTCCTGCACCATTCAATCAAAATATCTACATCGATTTTCGCAATAGGAGACTGATGTGAATCATCATGATTGATGAAATGCAGCCGCCCTGTTGTTGATCCTCCGTACCACAAAAATGCGACTGAAAATTCTTTTGGCATCCATGCAGCGGTGATACCGATAGCGTCTTCGAAAGAATAAATGTAGCCAAAATGCTCATCAACAACAGCGAAATTGTATCAGCCATTCTAGCTTTTCAGCCTCGTTGCCATCGAAGCGCAATGTGGCATCGATAACACGTTCCATTCATAATCCAGATATCCGCCGAGATCGTTGTGATCTCTTTGGAACCTCTGGATTGCAGCGGATATTCCGATTGTTCGTAGCGCAAGACCTAGTGTATC
++
+9)Y'FODZJJ3pM/cKH<4A6>BR35`[@X9*]2,T9fMboY]*=6MmE9PN~9[3AT?7+J:<4L3AI8My0~)S612N>^B>5>DvE;6HjU;BEA:EK&E4%`=6+B;Q?P5cD,_@=1?JrKCXCQ at E3<L4H?MKZ)TI5%G*@WB2~Z4<GJE.S=I~KL4I/9<=I3~4Db8;QLQ3ihT[~?=SNw3P)<@C`05_HE/3B=RI?gPM]HH9>l@/;FYK9J55P>B?:F^N9MM'KDNdC>EWKt<~]EK477L%c5 at 70=<>@+?AbC?@7eI\:<[6Z`MB2AS.zGJ/bsBL)83oN[Ol6OXB/1)=@ORE6H%E8&ID~BF>M-LS|BP58&(KC,)]46S>55:O6^IE?7`1;~;;A.U+AWO;:27B=?6YaBI1N;(3X;H5;aT0>(DT9;2ZQL=CA]>?N>YC)]I]F:AX7I=d'X
+ at S1_9
+GAATGATCCGTGACAGCGTGGTATGGCTGCAACCGCACTGGCACGAAACAGCACGCTACCGTCCTGTACCACTGTCCCGCATGGACGCTTTCGCCTTCGCCTTTTTGCTGCGGGATTGGTTCGCCCGTCAGCATCGCTTCATCCAGCCATGCTTCGCCCTGGGTAATCTCGCCATCTACCGGCACGCGATCGCCGGCGTCAGGCGCAGCAACATACCTGGCTGCACTTCCGCCAGAGGCACGCTTTTTTCACCTTCGTCAGTAACCAGGCGCGCCTCGGTGGGGTTAAATCGAGTAATTTCTCCAGCGCTTAGAAGAACGCTGCGTGCGCGTGCTTCCAGCATATGCCGAGATTGATCAGACCGATAATCATCGCGCTGGCTTCGTATAAAGATGTCGCGCTTCCATCGGGAACCACTGCGGCCACAGGTTGACGCTCATCGAATAGAGCCACGCCACGCCAGTACCCAGCGCCACCAGCGTATCCATCGTCGCTGCACCGTTCAGCAGGCTTTTCCATCACTGCGGTAAAAATGGCCGCCGGCGAAAACCATCACCGCCAGG
++
+X<JNO~fg>\R~vw~lpC~~Z{ni]Q~j~c.Ci~>g|m~l~~cj\`3~V~bsa~@m~~9~K~wc~~|eR`~~DLJe\~Hv~[~EW~c2rT~lAb~~~aA~~~~~,~G]~9~^_~her~g~J4f1PN~Ct~~`~n>~TO~~S}WaO~~~eZ~_G~a\J;Q~-P~q~~J~~B~~o~`~lRm~[6HS~Yr~^qfJ~K~Z~~D~~~|Y~~<A~^<~M~P~Wp{cI~r~~B6~~~Ski~~;mzH`~~H~~\i&~~ctu~Ze~G/x9TJY~~^VNjd~Sq~M~5~_~`~q~A3uP~T7?N\~~i@~~X~/~eO]hKkQ[W~>^s}^a~ah~l=v~~YpQ,q~SoRjj~~u6k}MDH[k~~~~7uI~mgL~g~aiAw~rK~~~~z~~~UKb~~K~ZYb~os_~FpXPO=qHnoDn~8OnX]~>~~zK(~~od~I[kdnjW~x~R~^~oqmx~Vho~~i~~WY~SeYm|~7~l|~~N~~lW;L~[cZ@\t:D~H@~rKe60U~Z~n@~U~PozJC~rP~~~|~~~|_L~tOv~~~rX~U[`g{:a~~~~d~~EXT~~wB\1X~~7gSEVje
+ at S1_10
+AAGATGCGGGAATCCCGCAAGGCGTATATGGCTGGCTAAATGCCGACAACGACGGTGTCAGTCAAATGATTAAAGATTCGCGCATTGCTGCTGTCACGGTGACCGGAAGTGTTCGTGCGGGAGCGCTATTGGCGCACAGGCTGGAGCGGCACTGAAAAAATGCGTACTGGAACCTGGGCGGTTCGGATCCATTTATTGTGCTTAACGATGCCGATCGGAACTGGCGGTTAAAGCGGCGGTAGCCGGACGTTATCAGAATACCGGACAGGTTTGTGCAGCGGCAAAACGCTTTATTATCGAAGAGGGAATTGCTTCTGCATTTACCGAACGTTTTGTGGCAGCTGCGGCAGCCTTGAAAATGGGCGATCCCCGTGATGAAGAGAACGCTCTCGGACCAATG
++
+;K?YKd)0B[,=CJ@%/:Ll<)(RVGZ4%MHI@)E1=FGSTJD=L:KRF?09AC,J/;TA*A0TVI;EG\MO`GBzY42R_9,MPB>8Q7*6)D>8DKQ0fD8YAL7=X>3RHFYN at 9~7B)PXE30-V9E32Q)GC9dMuAZG)P>B*L*YN40J<8.DCIKIQ.8ILENK$II?O>W4-9*4 at DT0NaIGbLG.26NVMTZ.BECG\LNy<33OK=7PI8NFc='.\O;~d5. at Ma>yIBmlxB-JT;RBEE?T9 at _4E7CBNG9TDrSDA2U@H`AR88I13?n at T[`MBAEF?S?:Q7RG>J(=dB35-2J8EI%MZ:AL.%;T5L0<a:bI;<~9RCP8IASDA59<S+*\@=/e?7:KV7=DE=OL5\;5L0M2I=TBNXN3FT0<?N%H<=2X
+ at S1_11
+ACGGTGTTGTAGTCTGCTCCAGCAATTCAACTGTAACGGCAGCGACAGGGTTTCGCCCGAATCGAGCCGGAAACCACCGACACCGCGCCAAACTCGCCAATTGCGCGGGCGTTGGTCAACACCACGCCATAAAGCAGCGCCCAGCGAATGTCGCAATGTGACGCGGCGAAACATCTGCCAGCCAGAGCGCCAAGCAAAATCGCCGCTTCGTCTTCCTGGCTGCCTGGCTTAACATCACCGGCACCAGCTCGCGCACCAACAAACGGACACTCACAAAGTGGTGACCAGACCATTCCGGGCCAGGAGAACATATTTGCAGATTATGTTCATCAGCCAGCCGCCCAGCGGGCCGTTAGAGCCGTAGAACAGCAGAACACCAG
++
+E^}AMGC[UN)Fi''d2INITc~^)~DEU5\XiVw%[y\&I]/~L1LPM|waKU>KD?`zELC:cwp=gS>~~ATL-*~>YS[3vuP>j~k;:k+~`vkC=-~w(OF/Q(~zEZ~>S at 98~\C4Q+_$XTCRV>MG]f8~Q6slbUc0jW<cF<TT?ETTwo9AeUU at IL{XQPO,8~f[V\<ZsaAg4jI\KQ~~kB;~\eU~Eg~LPPl:?+QiOdXEGa(N&[Kl~DfX58EK~ETMR;Fc=TUJ5~^LLMXL9d(44QLwHc.-gW?4eRn\n<6~nRJ('cM:S=~HL8BiwEnLZ3PMG5r?~]<SBDTBfb:H~5_9@^Zl.Q&]FAwJ1OG1?AWNC~M3]F;J:VQHG?~7MZiQXLY]~)Nu~k5BdS2O
+ at S1_12
+AAAGTAAGGGCGACGTGAGGGTGGATGGGCAGAACTCTCTTCTTGAAACATTCAATATGTACGTAGGGACATCTGGTACGGGTACGTTAACCCTGACGAATAACGGTACGCTGAATGTCGAAGGTGGAGAAGTTTACTTAGGTGTTTTTGAGCCTGCTGTAGGAACGCTAAACATTGGTGCTGCTCACGGTGAGGCGGCGGCAGATGCCGGATTTATCACCAATGCGACGAAAGTGGAGTTTGGTCTTGGCGAAG
++
+n~=]O70>fDMRMC{~~1FG=0EG5:~[:Qj(O)L$lO>YPI~]ZSYEW]Jgc]sTTpB^J6MVjwVJ7RdG~K2F~_HF<bp~>aAcWP at aF[HuE]D:BfP|@T~@EFC?i;;`|JQBYN`]s8V|RW3QLTMZ<:W?>WL+dEcKL*\i?LQ6C:,Rd64~KBFEJ[QVE\G6)lA=T~*g7S|8KZZ~ONsWa~~sWOOZySOXJ`k&\ThQ:MITlcPGB8~+3YWK;86d\ULiGCjboHE^RJ+I=BM
+ at S1_13
+ATGCTGCCGTCAATGTTTCCGGCATCCACATCACCAGGCCAGAGAGCGTAGGCCAGTTCGTCATCCAGTGTTTTCCATGTCTGCTTGTATTCGCGATGAATGGCAGCAATGACCGGGCTGATTTTTCCTGTTGAATTTTCACTGTGCTGTTGATTGGTTCTGGCGCGGGCGAGATCAACAACAGACGTGTATTTTCCGGTTTCCTTGCGTTCACCTTCGCGACGTTTTTTCCAGATGCGCATCTCTGCCTAATTTCGGGCATTTGGCACCATGCTTACATTTATGTTAACCCACCGATGGCATGCAGCTTAAGCTCCGGATACATGGCGTTAACTTCTGGCATTTTCATCAACGCTTCAACGATATGTCCGTTCGAATGTTGCCATGTCTTCCTGCAACAATTCCTGTGCGTTAATAACCATATCAACGGTGATGTTTCACATGTGTCGACTTAACCATGACAGCGTTCCTGTACTTCAGGGGACAGCTTGTCAAAATTGACGTTCATCGGATCGGATTCTGGTTCGACCGGAATAAAGGAAGCGGATTCCTCATCCCAGCGGTTTTCCGCATATATTCAGCATCCCAGGAATCGAGGGCAGGGCGGGGTATACCGGGTTTATCCTCGCGACAAGAAATCTTATAAGCGCAGTCCTGAGCAGCCGGATAATGTTCCAGGAATTGCCAGTAAATTTTGCGCGGGCGCGACGTTCATCACCGCTTCAATGGCAGTGGCTACAGCGACGGCACCTTCTTCCTTTATTGCCTTTCGTCCGGAATGGCGGGCGCAAATAAAGACTTTACTCATTTTGTTTTAACCTCAT
++
+=0S'A.R>?5);/;1>&MiR*K7>?>;I*E??:<@nA%>CJ**[=5n>.fWE8H3O6/199F;H1>66?6U89>K9IJ:<JNCCC:?U?EJUX33CF>V5J:-ERVA3GlC*9LF&4H=7%65[>=BG>*?7<C?PA.-MB6<&.E at R='4&7%d8%-+?EB90IR*:@EH2$GG/<7@=8J=1Kh?LB.9855&*0A^574=7%Faa@?<R9<BEZ/)AJX<+2=D:*CC:;B3;O2T<HPNC8=N7/U;[OM@,74$:;07K7?I2GE/'-&2=>A7D?4/U,F?X=*NO414*4?I?HW at P=69%:11S<89?@S&)>P=5+E8M4C:>A=;AHIB0>8AX1=&6T'9<U8E?)@:J3I8865W at A+4,;9 at -9@;6B75*C^.3))@6M;BCE+F60>:,MX33(0(1=7I.JR9M]V/896>@:4N at 5I1C4;NK-<%AGI4 at E/;2A@?=:@*I8<NB4)5&$CL-,L3M/%V:/9 at H<CHL3L. at 6%E*A`AA/<35J^B=b at N.<<;R,15L?VU9=C;)/'06~Q at 7N2J96D>GB<1G0h,3U(A:E?^9,CC, at 3UWWF74T9>@JFK>EUF/^K*19@?=3F+IX&4;5 at 02UEH5UAH0?$7&KRF2=ID3>6>b7H:@8,657*?4DJ;FK45CDh9D6)PJM;I0DE5&7 at JB/8P8DK*>A8D6L(=.B9<>741>=]?J?N<3FL@;1BSI=AALC+>I^\6IG=73<9?>4>Fc86S)<LM<W`J,)7Q?6EM'11H/*K0L8Q82F45DAC. at BX1DIAG+7BB%7;0:483,H+6%8*DXF8&8JF?A762B;L0G48C&2:-=
+ at S1_14
+ATTGCCACGACAATGCCTATGCCGGAGTACGATCCAGAGAATCCGCCGATGCTCGGTTTCTTTATGGTCGGGCGCATATCAGGAGATCCTCGGCAACATGCACAACCTGTCGGTGATACCGAAGCGGTTGACGTGTTCGTGTTCCCTGACGGTAGTGTCGAAGTGGAACTGTCTGACGAAGGCGATACCGTGGCGGACATGCTGCAATATGTACAGCTCGATCCGAAACGCTGTTAACTCAGTTCCGTGATCAAGTGAAGAAAACCGATCTTGATGCTGAACTGCAACAACAGTTCCTTGAAGAGTTCGAGGCAGGTTTGTACGGTTATACCTATCTTGAAGATGAATAATTAAGATTATTCTGCTGGCGGGTCGATTTATTTACGTAAATCGGTCCGCTTTCTTTTTATATATTCTTAAAAATAATTTGCTGCTTTTCTTATTAAATAATCTCCCTACAATCGCTGCATTAATTAAATGCAGAGGGACGGTTATGAAAAAATGGAAAGTACGTAGCGCGTTGGTGGCATTAATCGTGCTGCTGGCCGGTTGTTCCAGTAATGCGCAGTATAATAGCAGTGCATCGGGTAATGTCGCACCGCTGGGGTGGGATGTGCACTCAACGGTTCAGGGC
++
+FW6I at 26DP@O at 0Y.EFN(OH~*OM7MJIdI7467G=@00V8Z<BvX*-9RK96R|@E$@UII&VVGEI-'CJ]41Z*5<;=(]E5[nN[>d[>j/F_&F$)@&eG26IKD;'\7^/B86My2qLA.;>/XM1IN at 89HYa3E;@08DFBMIRXHD<,4,4?RI*\A;4-DAG-O&E=ZB4H1yUOCDTKG=.N=2JQAT8<:S??5;M-O9+[8[&/PUQ>E8B9N2 at E<IXgSH=>`@QLKVG;/H?YS5HMQ.zDG?-]?g77FFcW=NF+e4=+2.;l:\)-=>ncP?VD>-0;%+4>3NO/9B3OERM6L1I+CG%I&75MII>IL\>W$C<H<T?7IB@=G at O0>00NK;B=d7=%B,7BEE/7?CA>oY.a;V**<DQ&RI=/V*B=0L4KG:\=1LNAGT>9)QI>;ANB.AF;C+IH0SILA\,FH4(E~O4?ESOW9V=L;:&QK%OR5OXIJ;FIBfEBMM7HZ<V3567BU8ID8OK at DF@EX~E=;/4>S>&LLW88 at R-9*L3ISU at K@VGI63}C9CZ at Y9Cc1.5E[94;<<cCD>5;FQaQg:IFPZ%&3D;HHUDD/KRP>/:8TRD?kSE:/EU7AV8gM]F=OA67C>~YBHB<P'-NU{';E7D=-0;R(8CQ
+ at S1_15
+TTTTATCATATTTAAGTTTAAAATTCATTGAGAATCAATAAGAAAATCAAAAATATCATTTGTTCGTCTTTTATTTTTATTAACACATTTTTTATTGCAACTGCTTTTATTGTGTTGTTTATGTCAACTATAACAAATGGCTTCAAATTCAGAAGTGTAGGAGAAAATCATAATTTAGATGTGAAATATGCTGGAATGGACGAAGGATGGTGTCATGTTAGCGCAGAAGGAAAAAATGGCATACTTTTAATGAGTCTATGGCCAAATGTATATAGGTGATAAAACTCAAATAAAGA
++
+~)i~i~~ds~m~~~~^f~JFR\>2~ts_~~,t~VbR-L{_3~A~~~B3p1I~I~~~sbBcH~~~J~C~KnDNkN~Y'~E\pTI~R~d~Jl5>M~~F~~=~H~~d~xl~Nw5~~LhE~~~~Q~~M]wXNQI~HA~q~[~~Yii~_|[Ur5~O4k~P~WW~kO~cWW~>a~m~H5qWh~p~i[7Xv~WjPpGj~~~~(~~ao&~~~S~W~[FOd~j<~~[~Hg\~MVm~~~IY~8~r=n~~~~~B~T~[88M~jmxg~~Po~]~~LcXS~~.w~~~N2bm~f~~~4O~uIOK~[~rkR
+ at S1_16
+AGAATAGATGACAATTGCGTAGATTATATATATGTAAGATTTGACAAAAATAGCATTTTCAAAAAACTTACCTACTTAAGAAAAGAGATGTATTAAAGGGAAAGCTCATCTTGATACAGATGTAATGGCTGATTGGGTAGATACTCAAAAAGAAATTAATTTATTTACTCTGGATCGCTCAGCAATATCAATAATAAAGATGAATTTAACAGGAAAGGTAACGAAAGATTAAATGAAAATACGAATCTCGCCGGGTACATGGTAA
++
+4B?8LpdR=VTanGQJl~3,w~~\uXl6cRapQ\~\ScAa6j@~xbHaM<d5:NPbmGUWWGOs/?TF]k5RZF at TiV0(Pk6Z/V;w\`Q/ha~T\P}JH_~be{2VA8Xb~M;_4EXOdvREYNxG(RO6C<p45~KGc2lMA&>F.lSR`7o8EO>0.\;FU`9KJSO=GGYV2oZ7KAY<3A*J_ at McYFjB5~J?RvJxAdPEH|Kg;f\A.^HOZiCF<6E~f]>GVW~S9?rO9+E*R*~TMG4:w4>ezPd]~~cRF
+ at S1_17
+CGCCATGATTCTGGTGATAAATCGCGTAAGTCTATCCCGTTGATTCGGTAATGATCCCTGATATGAGAGAAAACCAGAAAGCGCGTCAGCAGTGAGCTTTTACCTGAACCGCTGCGACCAACCAACACTGCACGTGACCTGCTGGCAAAGTAAAGTTCAGCGGTCCGGCCAGCGTTTTACCTTCCGGCGACGTGATAAACAGATCCTCGGCCTCAATGGTCCCGGATCGGTCGATGCTATTTCCGTCTCACCGCGCTGCGGATGGGCGAGCGGGGTTTCCATAAACGTTTCTCAGACTGTCAGCTGCACCAACAGCCTGGGCTTTAGCATGTAAAACGACCGAGATCGCGTAATGGCTGGAAAACTCTGGCGCAAGGGATCAGGCCAGAAAACCCGAGCCAGGTCACGCCAGTATCGTAGTGACCAAAATCCAGCTCGCCGAGATAGGAAAAACCAAAGTAGACCGCCACCAGAGCAATTGACAGCGAGGTAAAAATTCGAGAATGCGGAGGATAAAAACGCCAGCCGTAGCACTTCCATTGTCCGTGGCGGAAATCTTCCGAAGCAGAACGAATAACTTTCAATTTCAGCTTCACCACCGACCAAAAATACGCAATGTTTCCATCCGCGCAGGCGATCGAGG
++
+8bHGI1PBM]E1XG7.E at MFMG4;VNO;V%76nA'67<SD;.NP:E'A6:LC0++B==);%QE%&5K835&0:;*7-,;T&6A19189D:6DK>2M6'2?6GE30H(6:=2;H7.C>=&1:7:39.ACDJ1>*PF3D6'*HH$(+.EA.37?*35<9N,(2J at 5EJ%PA(=O8=U;./?5QM7_A,T^a??E9B=*U>=?)[;:\O7-?NP<4FWMKN88;:'6?&O=>9>,8==K98T;28O[*K8;32GCA7=C88-9F0=@B=:>JLV?18&H092:@\@DI?LBP_%.C=3K=.8J]I8D.9<K4CF7/J>U89 at HMAP>A-8A41:FlG:CB9hO(FFE(4CSBGD=L@%Y2M?])X3 at 3.39>F5+^~I&GZX9E/9*F:&<H at WK'0S57CC8:;;9VGRE3:AS?`iIN?4B,1g/9RT1 at +?^>=M`362<DJO26:~0S48?X7EKG.%83)KG?146=<40G.:)'P3=C@&A;3X09=%A?KM+?,O').2JH,NJ>BI0EK6- at HIV4J)I/;:E(5F,R<<D*7=@V65CB+61L+C+;E:@C6IF*>Kc=5D*,D1@=]F-(&K;B=%(E:.92S,5Z<5<3<(8.3PB2/440+D7 at D95A>CJ;5AQE:9WL;I=02B99P.?^J9
+ at S1_18
+TGATCAGCGCCAGCCCTCCGCGCTGTTGGCTTGTGCGCCCGGCGTCAAACTTAATATCTGCGTATCGCCCTGCCAAATCAGTTGCCGAATACCGTAACGACTGCGGATTTGTAATTTCAGCGGACTGTTTCGCCAGGTTTTAGATCCCACGGCGTTCGCCAGAAACACCGTTAACGTTTTCGCTGTCGGTACTCAAGAGTCGGTAGATTATTTCGCTGCGGATTGTCATAGCGACTACCCGTAACGACTGCTTTCGGCAACCTCGCCCGCA
++
+:hKpxxYouH~V~TeZa~O~BiwF^U~x~]g~~xjT<r~ejX~[o~c~~vz~~=~TZl~~~^~i~a~v~Z>Vvp_Lk~~WP\~Da}^j~Uh~bLFO]~sGM{MrRpm~Je~]~~g~M~TK~~~=~~78nwLjX\Bm~b=u~~~c_QL[~cjh~Wn~~r~XP~~W~}~bA{~~mp~~~B5akl~esP<\p~xpZQ~V}fgnFVUd~~Ga;~~\Rg~tev~2[^]ds~~<e~t\Ry~~t}Tz`~&v?pRlMMZX[}~~|Q~~~^R~-~~`S9~
+ at S1_19
+TCCCAGAAGGCCGGATTTTCTGGTTTCCAGTCGCGTAAAAGATAACGACTATTTTTCTCATTTTGCAGTGCCATATTGTTCCTCACATGCACACATTGGTAATGAAAAAAGACAAAACAGGAGGTAAGGCGCAATAGCCAGTTATTAGAATTAAGGATGAATTGGGTGAAGTGCTGATTGAAAAATAGATAAGAAAGCGTAACCGCGGGGGCAGAATGGGGATTAAGTAGCCAGATATGTGTTACTAAATGTAACTAACAAGCTAACCTTCAACGGGGGTTAATCTTTGAACGTATGTCATGTTTCAACCCTTCAGATCGTGAATCTAAAGGGTTACATATTAACTATATTATCAACAAGACCAGACACTTTAGAATTAGTGATGATTTTTCACTAAAAAGGCCATGAACTGGAGGAAAACGATCTGTCCAGAAGGTCTATCGGTTCCTCTCTTATTGCCTGATTGTAATAATCGTTATTACAGTAAGTATTGTTTATTTCATCTAAGGTCATGTTTTTAACTTTTATATTCCTCTGTTTACAACTTCCTCT
++
+~aI2Z~~gWT3~z0~WTYd~O~r~~}jY]c~<t~@~~vL~~O}YPOsSk~~jsTTY~mv<~S~q*~Vn^eI3ct[c~~{CWo_zrw~W~^\~_S:K~[~IowL~RVb~~~~9N>~~he=c~b~~d~Hc:vquSl^T~~=ox~tt~Y_X~d~\w`B>[QV_~w~~~IF~~NW\~|~m~E~j[[w~~~~~~~QpU~PN~[~wX~~.{hobsK~~jZ{+~S~nD~~^vBonOT~iS~j~N;Cp~~UV~~V~~~U;mJO~2~TQ~O~5~~~~~~d~`gCXMJ1~~=~^~~@-gZ,Tl~WP~~AY_XI~~1>~LAx/JtK~ZS~~\~8~cDA~~LRTgJ~/L~~\~_H~~@~?Bj~dQ}BypL\eF]h^kWJ~~~~|;~[~r~~}cl~yO~@~~O~~pS~@XGnS~H~~~T{f~Z~_~r~~\{^=~H|PJc?f[vhI~L~aOQxJnoZL~G~7q~~e=oz~~~RCG~S{z~?~.~~o8Dj~0V~s~y~~~g~~~;~~m at oN~a~{FuQ~ii{koP~n~~^~~Nq~3broUH~~Z\re~qKQ?~ka8`~}@ZX0X~~Y
+ at S1_20
+TTCGTTGACTTCGGGCGTCACGACGCGAGAGGAAATACCGCTGCCAGGCTTGTAGCGCAACAACAAATTATGCAATCGCTCTTCTTCAATCGGTTTCGCCAGATAATCGCTCATCCCTGCGCCAAGCAGCTTTCTTTTTGCCCGGCCATTGCATGCGCCTTACCGCGATAACCGGCGTTTGTTGCTGATGGGGGAGCTGGTGGATGAGCTCGCAGGCCCGAATGCCATCCATGTCAGGCATTTGAATATCCATTAAGATCAAATCGAACGGCATCTGTTTCGCCCGTCAACCGCCTGATGCCGCATCGCAAAGTTCCACATGTTGCACCATATCTTCCAGCAATGCGCGATAAGTTTCAGGTTAGCGGGGTTGTCATCAACTGCCATGACTGTCATTGCCAGCTTGCTTTCATCGGTTACAGGCAAAAGCGTGTTTTGTTTGTGATGACAAATTCCGTCAGGGCAGGCAACAGGCGCGTAGGTG
++
+{~a[X~~Xd~7l~V~i~3tC[SPs~x~PI~nr~~~~~kW1PCnK_TcYV~N`;L~u~mt~V~D~~~~fD~TZ~~T;9~^Ci[iZk4~DpYwuS~]EZB\c|slpK~`~fn@~~\<`^~V~Y~Cobfd~Zp~~~f[BSk?h<~P~;VFO:L~I@~gi3~.\T~FMOS;PmH~s~~Y}~P~~_\~fI`~KAlXFTNXePH{~UH[~~cp~wQo0qTTix~djWkvZh~n~~~P~GZn~~~j`~~Mf at d~j~K)7ea]~~}ai|v_r~~Yhrrxhb~~U6e~~`n~~~~ouw~D at rUdY~l~ZEOrX~X\~kE`}dQl_L~~r~~{`I~g~a6~XRps7~~yJt:~8:GcQ~~~~~S~~GPdYTbti~~Xu~~~X~_[~jn~Ula~Kdr~[~^z:pUYnSuK~\~.~@Gj^eEb~XT~~~~>a~~fo~~~*K8iWlW~ubT~~]KuzNlK~IRP~~|TjPGVJ~~dg<M~Sc`E~ojQm2_[~`o~H
+ at S1_21
+CAGACCGAACGCATATACCACAGTGGGTGACATGATAAAGCCGGAGGAAACTTGCCTCCGGCATTACTATTTACTTGCCTGTGACCGCTGCTGCCGTTCCTGGCACCATCAGCTCTTAGCAACGATAACAATCACCAAACCAACAAGCACCGGTACCGAGGTGCGTTTTACGACTTCAAACGGCGAGATCTTCGCCATCCCGGCAACCGCAACGACTACGCCAGAAACGGGCGAAAGGGTACGGCCCAGGTTTGACGCCTGCAGCATCGGGATAGTCAAATACGCCGGGTTAATGCCGGAAGAGTGCGCCAGTTTGGGATCATCTCAACAAACGCATAAAACGGCGCATTGCCTGAACCGGTCGTGACTGCCGCCAGCATGGTCAGAATCACCAATACCAGCATCAGGTGATACTCGCCGACCAGAACGAGGTAGCGATAGAAATCAGACTTTGAATAAAGCCGATGGTGCTAAGCCCCTGAGCGAATACCCCAGGCGGCAACCAGCAGC
++
+V$KmTF<dLOk(JH<~~bh;(K6 at KFhU0~JZ~S@@vJ)1WT3/~A$w_Q2N~u]7 at A]D<l[iJ}0,1e5\H<`F9M at U^*3J|OPra~uXfT>~?A~Cb1\:~LMgWKJGLNb4~'[M~T7O;+K6CJI0<e{l~6YUQ2Z\R<PB<>L:dRHZEebUzpH5ZCYX7F~XIX2ZfTY\e6SDI~[[L=%HcH=;HmPN<NmDk~[HPGe,LH0j*MPNXQl:V`E]Ej=?-bPU[>~~Ra~^k_So>fGTFy^ZI-H\TD~W0;@`Hy[XIH6~hYh+=sFPP/zvfDUITA`XJ[8PEP;KUBHKX{<kfO4ER$?GDQNUe@~~W5L~VEI~EbHZ[RP>.EAE-=IF_pYAhW<MLF92Y at _~'6XJHsF9~U<~cS+@;[N\EHqc]'S5A)d~8;7?/M2~bA~RQ~O\H~IK2B{O%>UA?6~1B2C,AG^_EI%m4ORMNYtBYgbY^4W~=T)MH*NF5?2KV3~\TBtc~d/TEQ~bWU]i=L$SNNWDK\KacK<2J2
+ at S1_22
+GTCGGCGTGGCGCTGTTGCTGTGCGACAACATCCGGGAAGCGCGCGTGCTGGCAAATTGAACTCGATGCGCTAAACCAGACGCGAAAAGAGATCGAACAAGGAACTGCAAGTTGAAGCCCTGACCCTGTGCGAGAAACTGGAGGAAGTCGCGACACGCTACCCGGCGGGCTGGCAATGTATCACCCCGAATGGCATCAGGGCGTTGTCGGTATTCTGGCTTCGCGCATCAAAGAGCGTTTTCACCGTCCGGTTATCGCCTTTGCGCCAGCAGGTGATGGTACGCTGAAAGGTTCAGGTCGCTCCATTCAGGGGCTGCATATGCGTGATGCACTGGAGCGATTAGACACACTCTACCTGGCATGATACTGAAGTTTGGCGGTCATGCGATGGCGGCGGGTTTGTCGCTGGAAGAGGATAAATTCGAACTCTTTCAACAACGGTTTGGCGAACTGGTTACAGAGTGGCTGGACCCTTCGCTATTGCAATGGCGAAGTGGTGTCAGACGGTCCGTTAAGCCCCGCCGAAATGACCATGGAGTGGCGCAGTTGCTGCGCGATGCTGGCCGTGGGGGCGTGTTCCCGGAGCCGCTGTTTTGACGGTCATTTCGTCTGCTGCAACAGCGGCTGGTGGGCGAACGTC
++
+=e.>K%A==6LD9(*?A1+36d(C=B49M>DL%K88K\8751>/4A396K,AK/G6I$C0&8&'DOP>M4KB;M71<??5PC:FK/%./160)7FGF.5@:BF8$@>]BA4?HB4AHI4<>?. at 997+>,1Q4<G4%I20:<E/A=595>75@<L<KD?864G?E>63K>:F=AO*+DYME5.IF>4)1I:=@D?5EK%>8:48%CSBLN=?/.L:B+=K::K[)9GH2G6)/):EE7K?E6AMX<IA)4V<BHU3CDgM<JS-MK7 at C/C9]4GT3?'5I>FV5D0<ND77=GV8,5;H;*.:LOL*;O8F9A10I9AC&;=%E;NI26 at B:2?GBQK(ID6D6=9 at 9=GP;GR.EI<Q+>(jFAG8>+RJH2$@29D at M;=61PUOD:66Q8JC=)>=/;J;/J$9EDU?BS8JK62&1>L,:C5ME6M9FDJ:$JHE%34B/-[=S0>-28FA>>Z3IK-'$T;%42EHV=;+,:+&*AC6=P:k:NFE2MG260F*PYLL;H<'D?)GD3@/-=.'8:G)4=I)0?.*==;;5O<<X'2BH6HP5;<.K11A1iC9>6<>7O<,6;@4f6MH@/1M at B>TKE>%EEPF$MHKGGS?0=I0H0<N7B4;IG8-<:.D+?;A;E;D<93B9?7.E5$?
+ at S1_23
+AATAAGAAGAGGGAAGACAACATTAGCAAGGTTGTGTACATTTGTACACAATTGCAGAGAGAGGAAATGACATGCGTCGCCCTAACGATCCGCAACGGCGAGAAAAAATTATCCAGGCCACGCTGGAGGCGAGTGAAACTTTACGGAATACATGCTGTTCGCACCGCAAAATTGCTACCCTTGCCGGGGTACCGTTGGGATCGATGACCTCTATTTTTCAGGAATTGATGAGTTGTGCTGGGGCGTTCAGCAGTTTTACTGAGATTATGTCCCGGCAATATCAGGCATGTTTTAGCGATGTTAGTGATGCTCAAGGCGCATGCCAGCTATCACCGATATGATCTACAGCCACAGGTTGCAACGCCGGATAATATGGAGCTGATGTACCAGCTCACGCGCTGGCTAGCCAAAAACCGCTATTAAAAACGGTAATGCAAAACTGGATGCAGCGCAGTCAGCAAACGC
++
+^;:=@'<B<@14(7c&6_UEC/ZE-:DAJ^-6:>I=)4+>8IG9,4::GLB:>@A.=6G65M-0ORCUC4<~'EO/=5)3C1.C6G7H'@A7YE%L.CHIQ37<<2AU~1D/PK8E at C%A4A<2K<?XB85'*,>>6B<J7/^3=7<)=<1G).<:,%8EM.GU3H<(:<NE,9<@1Q/D9MVUjR8+T177LA4*93.5C>b5NYM*M?GG:22P-?f at 4KN+U-D688@>M)I4%0K:E,/A78>;:%$0LNHH><@9ICQ0E3;4:4CA873014A,5A5B$(Q>&%P7C7=P?;C<07@(/I28 at JYKU3[<IN=JO:.)3/Z5 at B45<J7-.>\EMT(7/%H<:455/T8QAK1DZ;V;44)P6&A.X/<,0F@@g99CJE at R(GA%E?V<6~9@&=4=B2A7VDP<@5-O=27)=P*0V?/G(>L@=+*BJ1[GOMFZB89C at DE?+6E'JMI9OBZP4
+ at S1_24
+CACTACAGTGATATTTTCTTCTTTTACGCCAGAGACATAAATATCTTCCACAATGTACTGCGCCAGCGGACCGGACTTGCCCGTCGAGTGGATATTAATGGTGGGAATACGTCGTTTCGGATAGATGCCGCAGCGTAATGTGCCGCCACAGTCGATTACCGCGACACCAATTTCCGCCTCCGCGGGTTCACCTTCTTTAAATCCGTCAATAGCCTGCCAGCCAGTAAGCTGTGCCAGTTTGTCAACAATCG
++
+SKRj~~[~/~I~}~Q^QUw[~=MGW:~Vkgj~w~9Gw^>cC~b~~a~~fpWPaS[~X=~rYS[~~_~^~~qwf~NOLFJwfQ~~g~nm~>F~YSu<vSPJ~~~~n~Jj~BG[Y~Op~l~Ws~L~R~lw~kpWXGSv~aF~i5~~~>IU^3o~~~P6V~e?S,HY~_~~~uo;xcxOU~gb~3~tlJb~{xz}c~~[LhH~Bf~~~b~~~N\p~=LkP^Bz,~[PYDohr~~}JoN~~~k~~~X~~S^~`fq
+ at S1_25
+CAAAGGCTCGCCCATGCCGGTGTATCCTGGCGGGGTCCAGACATACATCTGACGTTCAGATGCAATGCGTTGGAGTGGCAAGTTATGGCGATCAAATCACCATGCGCAACAGAACGCGTATCCAGATAACTGCCTGGCACCAGAATCATACTGGAGTTAACCTGGCGCTGAGGCTTAGTCATTGCGGTGCCTGTATCAATGCTGCGTACACCATCAACATTGAAAAAATATCGTACAGGTTGCCTTTCAGGATAGGTGTGCGCCACGACCAGATCC
++
+VIA}KOOL[H^CL]G0x}SL`u\YRA=GFHIYaXTxnh1R>eRH?zK9R^CDV~[<~UAD~X[L&~GogJJ^}[5:E@$UZCWDCE=~WK~DdZ`dYgH=~O{o>^_@[_jH`MY+OS$8~~:OIV%/KHA3UrYeVIa*lUIU0bFBF16.bAQ;pB>'G<4~baN6p at 8^iPEU'YUG^\IOZYHR}DC$M4~@l;1^I=;~KNBLnnPDCyP~Cs@~=P~HUtV</ZV;TN6*~5=R~\T~F5|V~pQr6MAK4TU9~}DSJ8D6?OIs=~kP
+ at S1_26
+GTGCTGGTGAATATTGTTGAATGCTATATGCCAGTATTTAAACTCATATCATCTGTCAGAGTTTTCCCGAAGAATATAGTGATTACGACAGTACTAGAAAGAATATAATTAACCTGTTGAGGAGGCTGTTCGCAATAGTGAAAAAATGTCGTTGAGTGACAGCGAACTTGATGCGGCATTTTATGCTGTAATCGTCATGCTTGATGAGGCAATATTGTGTTCAGAGCTTCCCTGTAGAAAAGAATGGCGTGATAATCTTTTGCAGATAAAATATTTCGGACACTCCACTGGGGGGTCGAGTTCTTTTTAAACTTGATAAATCATCGAATCGGGAAGTCAGCTGGATGGGTCTTTCTCCTGTGCCTGTTACTGGGTTTCAGAGGTAAATATTCCGTGGGTAGTAATGATGAAATCAATAATATATATCGAGGCTGAGGCGACAATGTGAATTGAATGTTGCAATCGCGAAGGAAACAATATTTCACTCAGGGAAAAAAAGTATAAATCATCGAGGCTTGGTTTCTATTTATTACTTGTGGTATTGTTGCTGTCTATTTTGTGGTTTTATCCATGATTTATATGAGATGATTTTATGCTTAAGAAGACATTTTCATTATTTCTCTGGTTTTTTGTTTCTGTCTTCGTTCTGTCTGTTTGCTATGTTATCGGCGTGTTCAGAAACTGGACAGATACTACAACTGCACTTTACTGGATTTCTGTGATTCTTGTTACTCTTCCTTTAAATTTATTATGGATTGTATCCATAATTACTTTTCTGCAGGAAAA
++
+~~~T~sYoGv~~JR<mlj*h~~~EU~~C~_2u~j~q~M~,r{~k~r~N@~}qnh~rO[|~~gib~I~xD~y~[L~R~~Otd~M~Gy[Z~~Ph7h~~vzP~[~b{~M|o~~Kc~FMy~X~m@~.~d}~=\~pen~F]~~~~dwIL~DtXMq~6Yv~mYv^cX~~v~~~yoe^~@W~uMm~]~~`O]Z~{~D~~~~Nl~~~=MC:T`~~p?n~~W~~c~}C|o~S_hd~~Kx<[~~^~c-Tjo~f~~aV~~JQO|SrJe:Iu~~~OxZE>[]p{Y~X~~\e~je~~gNC~S4l~.T~zq4j}`>\hzbJy~_W8~F~XYA~[Fk8G~~oF~<qI~~aoFo~~~;~o~~w9~v_~~b~}_]rHN~WCbgdm2OO~T~?O~~3^ZaU-~<g~N;EL~LUMxhj{f~M~tT~O~~p~Ft~~dY~xH~~~~~~aE^~q~3=R;~P~Tn`JJQ~sY\.e~sG~e~B[J~~~~~-~j~\~n~~~~[?9}Aiu}`X~M`SDC~~:~|u`{~~P~v~c~~gb~~3X~C~BUQ~]IwN~X~~~~~~RYwc9L~f~bUBZ]?Na>K~~~~q~lot<SoWZ~~^G`t~r~~~&w~Mh;~gv{7i~^B~tcA~Kr?X~}~\Zn6CM~V{~P~^z~x`BkO~~=a~cT~M~~X4U[FeT`~~`~~~kp~_~N~\7TQfW~x~z~~~;~~AC~~U^~AzJ~8~:~G~~\ZQ>~~jf~NX~D_t}5~8~~~~rknaa}U[~s[~E[^]Gpyvd4QF<A~|~xd`~~q[d~fRP~DZFTf2~Dy7~~J~~CNZkaidK?ot~-~
+ at S1_27
+CAGTGCCAGCAGGCACCAGCCCAGGCTGGCATGGCACCAGAAAACCAGGCGCAGGCCCAGCAATCCAGCGGGAGTTTCTGGATGCCGCTATGGCCGGTTACATGATGGGGCGTCTGATGGGCGGCGGCGCGGGATTTGCACAGCAGCCGCTGTTCTCCTCAAAAACCCAGCCAGCCCGGCTTACGGTAAATATACCGACGCGACGGGTAAAAACTATGGCGCAGCCCAGCCAGGCCGCACCATGACCGTACCGAAGACAGCCATGGCACCAAAACCGGCGACCACCACTACGTTACCCGTGGCGGTTTTGGTGAATCTGTTGCCAAACAAAGCACTATCAGCGTAGCGCAACTGGCACCTCTTCTCGTTCAATGGGTGGCTGATACCGATGGAAAGAGTAGTATACCGAGCGCCGGACTGGCGTGAGAAAGCCCACGAATACGGTTTCAATTTTCACACCATGTACGGGAGCCGTACTGGTGTGAAGATGCTTACTACAAGTTGACCCTCGCCCAGGTTGAAAAGCTGGAAGAAGTCACCGCCGAACTGCACCAGATGTGCCTGAAAGTGGTGGAAAAAGTGATCGCCAGCGATGAGCTGATGACCAAATTCCGCATTCCAAAACACACCTGGAGTTTTGTGCGTCA
++
+g=~^g~p\~X~|?Rn~TQ~>GM~I_~gk|a~Ig|W~ev~Y~~~~~A~?Xp~PlcH}R_N~~~t6u~~~Xs~PMf~~Zkww~ouK~~~~G~f~~~~Ijh~~?f~6~n~T=ez~~:@Y~~@~kma9_GN{u~ffNTjE~BHxmqpAvb`OFh~a~BR~QcuuJ@?FE\-~dJ[~j~v~B/D~U~`=~w.~~ai~h\~^~~=~~`eA==~J~~~FzZ~Y~~NZJ~~b4j~jK~N~2x~A~~2[~~fG7Ndm~b~~~iX~~BM~~_}k1ktiFa~r\=~KU~~P\[~Q~K~t6~mmR~:5kzXb;~~L~~[/b5~~I~~~5c\~W{^X{cD~~M^}C]x~~~xU~x~~j[|Y~~J~fY~~j~~]~Q~;]f~~OZ4~~tfT~~\g~V=~r~~A~~Q~~~k~UO~TY~.VegYK_yw~~g~Vc{]JI]uuLGeQ[UgbDU~ok~~~cG~Ft^a~~n~~~\\~h~>s;Z-KqhjAU~~f~Yrk}~BhX;POao;zF~TLQUEq~_d~KOS>kt]~^eQeWPcfnTF{J^~Ib~~~EJ~VG~GbFh_U~_~QtG}~K~sY~PfI~~A~~r~/Z,cQUshO~NO]C{VTS~\O~r\qmPMO~=P~~cEE._C~\XFd~`gP8~N~MYgjmc~Di~~[E~RF:Z~`v+~]MApQ}m~
+ at S1_28
+ACAGAAAACACACGAAAGTTAACGTTGACGTGAGAAACCCTGGGAGCGTTTATTCTTGCTTCTACTTTCGAAGATGACAAAACAGCGGCTCAAACCCACTATGATGCTGTCTGGCTGAGGGATGTTTATGGGGCTATATGGCATTAGTATAGATCAGGGAAATAGTTAGCCGCAAAAAAGGTTCTGCTCACCCTATGGATTATATGTCTACGCCCGACCAGATTAGCGGATGCAAGGACGTCA
++
+F6>:77&9@=00.Z75:<-=,C:7FRDW62%/=<>JJ?5:-:B47'@J=C7?:K(1DC0,'-2;BI5;8>&=*CG:B831.>K>8UH/B$5A)>-E7:1F*27+Q0;@?EGC7B6G>-'6)3Z.G,K0<-'<88 at 4=.\1LGO1:4*+7(7:27=+9:4M?3:$?)41/08+V669A6;%5M8?1%@A:$;)0&$I'0,16<55P?B<&1=3.OP5R;'6;=6C;6?=>@Bc2$2,?%>=./K
+ at S1_29
+AAAATCAGCAAGCGAATAAACCGCTCGCTGTCCGGGTTTTCCGGCATCTCAATTAACTGGTTGGCTTGCCAGAACTCAGCAAATGGCGGCAATTCAACCTGCTGGCTTGCCCCGCGCTGCCGGGCAACGTTATAAAACGTTTCCAGCCATTGCAGCTCACTTTTTCCTTCCGTAAAACGTGCATAACCGCCCTTCTCCCACGTTCATTAACTCGGCAAAAACATCAAAATCATTACGCGCTTCATAGCGTGGCGGCACCACTGCTTCATGGCACCAGATGCTGATACTGTAACTCACCGGTCATGGTGAGATCATTACGCTCAAAAGAGGTAGTCGCAGGCAGAACGATATCCGCGTGTTTCGCCGCCGCCGTCCAGAAGCATTCAGAGATCACCCAGCTCCGGTTT
++
+I,EF=DE=*8;,&PM'585:I9:E63T=CNKa=)E[5T<LIMXK579?C/V<?MD8*-75>C4%F==>:<816J>,.PB7)+H,=ZW?+5JAU at -0(AC;(%.NJC[<@-H.2(GD%EGAa*2;CLA2<5C%II:.\9,?=O12<X:a0C,DF7,QDE-B=5BJ@'<?Q at APYI+:5%Q<C%BRLGK>]</aF6IKM39G7^C5651*5+&<BC9d;E>PD0N:h1GLU-A4A4>:'2=KK>6<00<+O<f@/:=. at 3a%M at 4<96M:>L378&6'1F-AE-CM>Cj at O^A5*M3;CA8D<+~J,6LJ?=S4AA,B4,FCA7SCD/AMH=?G??+08<c:W;C*%52IPT<=49D<(I785LAKPD$3/>/A<JD<AP4=KD>A at D'.=N^HE@,-IBNT.&?@83?
+ at S1_30
+TGCACAAATTCCCCATTTGCGGGTCATTCATCTGGCGCAAAACCAGGGGAAAGCCATTGCGCTTAAAACCGGAGCTGCCGCGGCGAAAAGTGAATATCTGGTGTGCATTGATGGCGATGCGTTATTAGACCGCGATGCGGCGGCATATATTGTGGAACCGATGTTGTACAACCCGCGTGTGGGTGCCGTAACCGGTAATCCTCGTATTCGAACACGTTCTACCCTGGTGGGTAAAATTCAGGTTGGCGAGTATGCCTCAATTATTGGTTTATCAAGCGAACCCAGCGTATCCTATGGAAACGTATTTACCGTTTCCCGGTGTTATTGCCGCATTTCGTCGCAGCGCCCTGGCAGAAGTGGGTTACTGGAGTGACGATATGATCACCGAAGATATTGATATTAGCTGGAAGCTGCAGTTGAATCAGTGGACGATTTTTCACGAGCCACGGCGCTGTGCTGGATATTAATGCCTGAAACGTTAAAAGGGCTGTGGAACAGCGCCTGCGCTTGGGCTCAGGGCGGTGCAGAAGTATTCCTCAAA
++
+9BK6XdQH[AJE?I<B)VD/T'6/=5 at FEB6Sd8'4ERQAHR='AJVCD>eLNCR/*8JG+7@%TPD>eJT^BD;:521,X at PHaaM<4N:F<Kc4UBZ2C-,<G=HQC.7MC~>Q`A1AE@)ZBs?JR;R;>WI=7GB-KLR6LD=|<CQY951.CDNJ5Ep_ at k9%_NAHAG4D2EVS>$L$55.*MUL_?)V5=B5:7H9)G@\M<O],Ot,;4C=\=,5NA?bSVB/@A>T+3M2TC+8H)J`E4ISD+$IDN_=g?RNW4F:J<@C4T.3WO at Pb,GB1hA~L?=%22N&J<I=~,5D[:J0?/[=DC4%BH%D>=DCU;XDnD6<bN5T*V;Q<E26 at J6ZI7O%^;DOdNI::Uc7G1?~=+Q&H;7*i@:G~+j]LTK%GJHWWF at BL5R*8k,79H:F+]D*<C<>K~?:'&CYG:LIADK,T/;/N](34EEC?XX.7HM8I71FCTF;LHMEM>~S:'lAaD;K?52tRW7Q@=M:EIGG9J3~)C3<D12S%AWO~%M3Wk;IJ>`F(W5;EKIF5Q9,:NZIEN?EO2
+ at S1_31
+TGCGAGCAAACATCGCGATTAGGTGGGCACGCGTAGTGAGAAAACACGCACTTTTTTACGATAATTTCCTGAGGTACTCACTTCGAGTACCTGAGTCATTCCGGCGCTAAACTCATCGCTATACTTGTTATAAATCATTGTTACTGCACGACTATTTGCGTATTTAAGTGCAGATGCAATATTAGATGATGTAAACCAAACACCATGCATATCACGGGTGGGCACC
++
+~~8`?{}fQMv~b_d{/jFPbHp~~]fv~~amse~|E_~EpX~~}AO~^C~~RSe?_~g~~~lQZQ{QspD~~~gn~e0Pn~~~~Qw[HCZ~~v~@~b?Q~MJw~a~~~~~`|Y~vmr~ef~~de~X?JIX~[Rn9witUg^dH~`m~~UePBPcZ~~`~x}~~~D1Ztar~~~~SM at 0~FS~PeEY`u~UT_~R>~3LZcl~~Zi~jq/~~T~~h~~~a~~{~m~
+ at S1_32
+CTTGCTGAATTACTGAAACCTGGCGGAAAAGAGATCCTATACCGAAGGTAAAGATGAAATGGCGTGGCTGAAATTTTTCTATGATGCCGCTCAGAAAGGTGCTCGTGCGAACGCGTGACTATGCCGATGTTTAATGCCTTCTGGCAGCAAAATAAACTGATCGAAATGCGCCGCAGCGAGAAGAACGAACAGTACGTTCGTTATCTGATTTCCGGCCCGATCCGGTGAAAAATGCGCTGGGTACGCCAAGCGGCAAAATTGAGATTTACTCCAAAACGCTGGAAAAATTTGCTATAAGGATTGCCCGGCACACCCAACCTGGCTTGCGCCTGATGAGTGGAAGGGTACCGCCGACGAGAAGCAGTTGCAGCTTCTACCGCACATCCGGCACACCGTTTACATAGTCAGCTTAACTATGCGGAACTGCGTAAAAAATATGCGGTTGCAGATCGTGAACCAATCACTATTCACACCGAAATGCTGCTCGCTTTGGTATTGCGAATGGTGATCTGGTGCGTGTGTGGAACAACGCGGTCAGATTCTGA
++
+2IEH?Q&RA7O'Y>@U>%GQ6tRL?88?6M%=>E=0==:4_+E3Qo&4<k;Z;0GKK5@\]@HI=fO,I)8FA0.G.ANP@,KMDHOFTEC/{AMKOUN at 8=%KAA:]^>K=Q>@<%E_5.O;@8>0~7XPA71BJGObCCH6;%x~>D]Fo)6?:FXHRN?9<D/=07:tM:5':D&I*:F><PPd>%FD0<2 at 681JBOI5*5F<Lb</7\BZ*HU at HOdM-.DH=&;3P<=TV]C^6U>@/V<CSC_Q:7ZLJ@<=@~CFJ7?DB]PK/40F>P-6;=%FF9HGJhfA;S'k(PBD)H6CPJ,3RCMAU->P<%>=<J3HC5GY;@?=*gUTr:=2O+GH2uNS=04J2=:IXYD5;:ZLG.YF>7LBII/PH6hq<2~SB:R=4=ZSrPDF7?BGIE,H5DO5LMC>WC6=1>*;Lc0),$h;@Q8?=J(YD2 at 9X:~M1E@:^T^yO?>6?=U4B.FS/f,I/T8<BG+h2UF at JVNQ91~$S64;:.BN?\>UNI4F88DM at A30<9]F?9F7A.X/5>U`9GP>7g:RE3[wH?.`J=
+ at S1_33
+GAGCAGGTCTGAAATCCTGCCTGAACCCGCAACCAAATCCCACCTGGGCCAACCGCATGTCCCCAGAGTAACTGCGCTTCAGCCGCCTCCGTTTCCCCATTGCTTCGTTCACCTTCACTCTTTAGCCAAATCCGATCTGTGTCGCTCCAATCCAGCTGTAACACTCCAGCTGAAATTGTTGGTGTTATCCGACCGTTGCCATTCCAGTTGATCCAGCAGAACCAGATAATTAATCGCACTGTCGTGAATCGCATGCCCCTGTATTGCCGAATGCAGCCTTCCGGTCGGCATCGGTAA
++
+CU4G*I8U<_.V*J;J>4HNJ=K09MC=W*U>Y><:&E1LS7E78V[H>D>>7*UC1=U~?*=I@(_PF*CNH?wVGYB<?5L~8FB>:KM(- at JUAc{?=T3m81S5>;DPB81-3HQPIXRM;T`PO^40NJ.tR9D5E)<?HATP?HF?CM24E at fK=BR.38@<CeU@~D4oi%OM~K1COH(<+u>?RDV<OIHHFT+`=8[IG&>F*WASCBC]QWJG?Y_DD\3/MF>-3I.NIBK*K1WDGMA?cB>K=I7W[M<H;L+QK2EKj8NIMn5<K}-~AAKS@[)<H><:@
+ at S1_34
+ATTAACGCCAGAGCAATTACAGAACACGCCGGGATCGCGAAAAGTAAAAGTGCGCAGCTATTGCATCAGTTTAATCTGGCTCGTAAGCAGCCTTTTACTCGCTGGGTGATGGCAATGGGAATACCGCTAACCCGGGCGGCGCTTAATGCCAGTGATGAACGGTCCTGGTCGCAACTTTTATTTAGCACGGAGCAGTTCTGCAGCAGCTGCCGGGGACTGGATCGGGGCGCGCCAGACAGGTTATTGATGGAAGGAAAAGCGCAATCAAGAAGCTGGGCAGTTGGCTGGCTGCCCAGCAGATCACAGGTTTTGAACCTTAGTGTCCTCGTGGCTGTAGTAAAGACCGGTAATCCAGCTAAGGCGTAGCGCCAGTAAGCGGGCAAAAAAGCCGAATACCAGGGTGGAGATAATTACCACATCATGGTTAGAAACATAGTGTTGCAGCGCGATGTACAGACGCGGAGGCAAATGAGACACCGGCATACAACTCTTTCTGGA
++
+/L;JZ=G:VOGY0~ZXCK~wBNAeIIahb=SQWLZDX*<~A at V*@DZPLG8^S6P~O~c~w1PAPxRo~Lju[M{}NT:~YCX?IuvUuJTPMhc~L/kHOIBym=RFO\~q\WhgA]8:7]HDA;C\>ldKAcFh[uqvEmc*>ERM+[Eo7\t3S<cc_C~]0BQ_s8X}~8YxL?G=WJc_hZgIkEuDTi'XhB6KI`G4q(~- at 2?nM$EDZ9J@;DA`lB7YA?4W[L]C<]EJdR~~B+~YrIs.J9eB8z~H9_^R<Li2q:NHJ=G[~1FhM~oqfI9~Dd*:Pa\K|QNPI[ugU~?QaB3??~f_FYIGL8?[rWiPs,aCLHh.1`Dh*6,~/R[5?e;I|53P_W.VYPV6tLn~=;c~~Qt-4DnE5_\(kOQS8DzchQU]\MZtG;RF[L5OM~gRK at SB^ijS8`2Y&ZH\9aE>~oRFEXjcEH/MUF^-<CF(`IZa2bM~Qc9<HJPZb2<fK~B`C~O<~Rx_~D>_3IYFsPOAy_
+ at S1_35
+CAACCGTGGTAACTCCGGTGGGCGCTGGTTAACCTGAACGGCGACTGATCGGTATCAACACCGCGATCCTCGCACCGGACGGCGGCAACTGGTATCGGTTTTGCTATCCCGAGCAAATGGTGAAAAACCTGACCTCGCAGATGGTGGAATACGGCCAGGTGAAACGCGGTGAGCTGGGTATTATGGGGACTGAGCTGAATTCCGAACTGCGAAAGCGATGAAAGTTGACGCCCAGCGCGGTGCTTTCGTAAGCCAGGTTCTGCCTAATTCCTCCGCTGCAAAAGCGGGCATTAAAGCGGGTGATGTGATCACCTCACTGAACGGTAAGCCAATCAGCAGCTTTGCCGCACTGCGTGCTCAGGTGGGTACTATGCCGGTGGGCAGCAAACTGACCCTGGCTTGCTGCGCGACGGTAAGCAGGTCA
++
+IkG0SCH7TOH<VRTGHR9~0G at JCJGE)M=)KeCXR1A~9?<0EC-5<=5P;dR4H?,$2@?6>\@D?WDI:6/5KD>=8]BZ6;+5+15E\F/ITD47NL7>9KFe7;JA63=PROgW8CP3 at YQ9O<CD>-[IOBG~OGR<0C/]:,1X]\)=Q5GFCA@[D=D;3BI:@AGE<,BG2fB*WWN%?=F^Q&4<L+lVZh2KO/8,4*'J$C,7LR7033>;DEo7jb at 6[_YJ'0.6D/7Xe:.J.<OGBCZy+7E>3~F?]A at baCCRlLJ^=0F@@L>86:8HC2=%1`P?NEK(@DT>8W;Fu8>?aN%C>GB8MSG7/>GV`;YKT-- at cM=^kMK9UK/7:FB>?@FCQ5L-UcP('7A<d48][:DN<H<fE2<aF[PM.T3;P:<RC10A;LLE<FII6<GMB_'?43/:~H^P
+ at S1_36
+AATCATTGGACGTCTGATGAACATCAGTCAGGCTATGATTATACCACTTTTCCCGGTTTATGATGAAAAAAACATTACTGACTATTGAAATTCGGCCACCAATGGATGCTGCATTGCCAGCGCGGGACAATAAAACGATTGCCCGACAAATGAACAAAAAGTGGAAATTTTGGTGGGGCCACATCCGGAACAGTATGTCTGGGTTTTAAATTGTTAAAAACACGCAAATCAAACGAAGCGGACCCGTACCCTTGAAATTATAAAGTACAAGTATTTCCACTAGTTGTTTGTAAGCGTACAGCCTGAAACCGTCTGGTCAGAATCTGACGAATTAGACAAAGTGGTGTCCACCAATAAGTAGTGGGAACCAATGAGGTAGCCTGAGTTTAACGGACACTCCTTCCTGAAATAGAATGGCATCAGAAGGAGCTAATAATGAGCAGAAAAACCCAACGTTACTCTAAAGGTTCAAAGCCGAAGCTGTCAGAACGGTTTCTTGAAAATCAACTTTCGATCAGTGAAGGCGCTTCCCGATTATCTCTTCCTGAAGGCACTTTAGGACAATGGGTTACCGCCGCCAGAAAAGGGCTCGGTACTCCTGGTT
++
+OMNUPUOSF`[YYXH(L_ZO~HXgFtMpMzQZ5_~FFNuZ~DFUZ\V8;(F76~XLU6-b)DLi,L;4XcaT3g{`@BT7B}~HWUQ~[T]KpqBW,9]I{=~]~VM~r/2:\_A.Fe~_HJ<~&:UaDD;~>nX>NipHUY@(IN0^Ca=HsGFu at XH@ZP<q6QeTGZZ[/y\LIatI at 3N7:R(I>6VoWPM_.B.8Y^f]GO;M~bo?kGF]V16gsLIP~o~]l*kOMH?hU5CDnpOK~R:RF~H?JNM32;e~uGKGLH<-M<F.0RM~iFRs)X7:mD?~L_m1g'KBIE*lOGuBW4~MKQG;x=Db>QJH~~Kf~mdHsf~6;RHPGG~OV0YA~~';?KQ>J~^8QO at 9,tA>LVKQ[J+E=[R:HCETKROS@@[OLXWNQrJ\?k at x~~~<Y?EaOGFXWl?TeW3A~]_PEo~Q]rL[m5T at DV~P[F<Ex6u\M~~LJJ[^CV~]OJ7G?JUQ+U/]X~_S0WBPF~ZM3Hv3\pd>%VC@,Ua0yPNSM at kQTiaXbL5SP~W at p9:qaKhP`DCYhO~D_dQ-F)Zg<OH\O^~4pf[G~OT\fp3GH)GiPVolWBIhaa@~Ntd3[=KX\'G?U:C\;XPJB6~V
+ at S1_37
+GGTCGATCTTGGCATGACACTGTCACCTGCAGATTATGCAGAACGTCTGGCGGCACTGACGCCAAAAATCTGGCCTTGATGGTGTGGTGTGTTCTGCTCAGGAAGCTGTGCGCTTAAACAGGTATTCGGTCAGGAGTTCAAACTGGTTACGCCGGGCATTCGTCCGCAGGGGAGTGAAGCTGGTGACCAGCGCCGCATTATGACGCCAGAACAGGCGTTGTCGGCTGGTGTTGATTATATGGTGATTGGTCGCCCGGAACGCAATCGGTAGATCCAGCGCAGACGCTGAAAGCGATCAACGCCTCTTTACAGCGGAGTGCATGATGAGTGTTCCAACAGCCGTCTGGTCTACTCAACGGAAACCGGACGTATTGATGAGCCCAAAGCGGCCCCTGTACGCCCTAAAGGCGACGGTGTGGTGCGTATTCAGCGTCAGACCAGGGACGTAAAGTAAGGGCGTTTGC
++
+-7*+84JBBDI<&C:<Q:,2OB^NB=84RE:'?=B;FX(NB880$4/Q/H,@:A;?)H7=~E'(1C<;B&KH9D=:SBJA:;D7&,NA:E,R;.[-7V*<[Q4M at 3G&L at .GfJ*?;<.8/G5,:GFFDJ104V?8079?N&69KOQIM?.&6:BEC9UMEB'U@,55:/7I0-D?n,7MC<:W9&/?Q,;AG]?L*8B==VI1@=E@@?V2>7DPML<5V9O18T';5C;5-2[EC1I3GFZ5 at BCV~-3V=BC8?EH7OEA>P*F*5>K%G6IKW<H<+>:@. at SD52%C;-1KERQfW4>E?7(%HK=98:Y$Y:DG-2:?M at 9@%H*Z&A0+;3+E@*,<^)<T[C1+MA.3D=I35:EJbOP:B>-F+F0*7A>5HENBJ>M%%04J?<.)M?`=?BEC9O3C$G<H]8Q6M57:Z*E'>8+9O*9<D++@]73=ADH*?D9Q[2J<5'=7:@D5/)F8
+ at S1_38
+ATTGTCGTTGACAAGCAATTACATACCACCGCAGACAATTTTGGGCGATGGGAGATGTTACCGGCGGGCTGCAATTTACTTATATTTCACTGGATGATTACCGCATTGTGCGTGATGAGTTGCTGGGAGAAGCAGACGTAGTACTGATGATCGGAAAAATGTGCCTTATTCCGTATTCATGACACCGCCACTGTCCAGGGTTGGTATGACAGAAGAACAGGCCAGAGAGAGTGGTGCTGATATTCAGGTGGTGACATTGCCTGTAGCTGCAATTCCGCGTGCCAGAGTGATGAATGAACTCGTGGGGTATTAAAAGCGATTGTTGATAATAAAACCCAACGTATATTAGGGGCATCACTGCTGTGTGTTGACTCCCCACGAGATGATCAATATAGTGAAATGGTGATGGTGCCGGGCTGCCTTATAGCATATTACGCGATCAGATATTACT
++
+b\/Oa\%SO{MU%JAj=4S;9G2PhO8Y.OSQ|V-[-a~AI;nJR7~M|AGdTJD9yKdZXG>S[~~^^Y~8gSA5I~C,<Wgab8uZBJGWMC|;AVV\BEifTeV~^V_w~RI_I~8HI>(pN~a_B4LQ7~0\dZJ@'99~J@]e at k<G.x?QR\~hOK2V88-yPLoQD^O]~~O=OJBBE>OoxNJ8WN_aVcIl~AHA~U~XA=SaUj'V-P>~^VeG5QhK,>C\<Y~p~yP at h4\J|K`ZZ~GID9M7I%QK?h86=e\rK?jA+QHZ\9GHg\Nhj~~@YNHU'?\>&J4KGXIH<caqW7~;gL~H6{Eb6[G7vd-W=k0ANLWY~IAT??_`H^7>GK~Mh.D^iG1_=k~ZDF/~LDRYA$JFL at QPHO~>BCX4G]hQRf~Sm~BD&PZ~PeE[,S>9dvF0w\:A9[P[?L~29 at H:b`i'Rn[TKVK?ObCJ=9Z
+ at S1_39
+CCATTGTGATTGGTATTTCGATGGCTGTCCTTGACGGCGCAATCGCCAACGTCGCCCTGCCAACAATCGCCACGGACTTCATGCACGCCAGCCAGTTCCATCTGGGTAGTGAACGCCTATCAAATCGCCATTGTCATCTCCCTGCTCTCGTTTTCGTTTCTGGGCGATATGTTTGGCTATCGACGTATTTATAATATGCGGTCTGGTCGTTTTTCTGTTGTCTTCACTGTTCTGCGCCCTTTCTTGATTCGCTGAAATGCTCACCTTGCGCGTGTCATACAA
++
++ULK9GL6UX-?'=|8Q;64+\KF8;h>C4;]'$GHGIU at D:6\HE1 at UKb]GHU4^3EP<6KL7:<RbDGSSQMA=77E[CAU2I'?Rc5B385>DXDR?BH7:L'm:GCD/<>G<N=B*Em61C_I>RRQ:Q>]WN82L/J4 at +0.3BF6>EOC*KCQU<c11J?~@HBBM3ICF0GMG4c<+LSBN<9G%E.B7BS%B;C5SCK?GIBE3OVFT()GLIEL6wEPS>P:)HTW0XG-C.r'VTGK7pHbHD%4C]gK:NjK>2EU'3:Y899A at U3JSP
+ at S1_40
+ACCATGCTTCTCAGAAAACGTCGCGCCGTCATCGGGTACGAAAGCGGCAGGTAGCGCGCTGCATGGTGATCGGGCGATAGAAGTTGGCATCGGCCCAGATATACACCACATGCGAGGCGATAAAGGCGATAAATAAGAATGCGGCCAGCGGGCGCGCGAAGCGCCGACGACGCTCAGGCTGCGCAGCTTTTGCCAGCTCCACGTCGCAAACACCAGTTCAAGCAATAAAATAACCGGCACGCTGATGAACATCAGCTGCCAGTCGCGCGCCATCTCATTTTCGTCTGGGTTGAACCAGTTGCCAGACGATGGGATTAAGATGGAGATGGAAACGAGTAAGACTTCGCTATCGATCAGTAATAGCGTCATTCCCGCCGTTCCAGAATGACGGACAAAAACCTCATCAGCCTCTGGAGCCGACGATAAAGTCAGCGGGAAGAGGATCAGCAAGTAGGTGGCGAACACCAGGAAGCTGAAATGGCCGATAATGCTTACGTAGGAATAAATGCGACCAGCAAGCGTTGTCGGCAGTCGGCGAAAACAGGTAACGGCGCCAATGACGAGCGAAAGCAGAATATT
++
+NTQViUAQ~mFRUK4K0noPIg1TAJDi6`9DFI}s]sJ[_`~0<bN?WGM`rQEnYF[b4Q2KY~EHrLdF>MI4 at s,T~OFS`XKJ]i<eH~~`~~kSKWVG5)K0W=XD[~nKF%RbRLSXJ at I5|@YGTCJI(SLXa5~LdPTkA:VeUuK^khibc>jG>Aa?Q~SC_PLP-+4CtJe>,@~qcaGR[=Wr;H5JDY\.u:CXt4YO?L\B[Gm=k~_P8GJ&M?KNqjQO\Q:TVe5l~PiHrJR^FCA=HG=iSFE<sRYT5g<KF~%DPRZI~~jC~3MELHp(KwxEMSxC5fKKPKL,~i:Xc~~_c7c~?XZHCSJ_:+_~j;6GUR6D6~~UYU/;Li5H>bMN1n~~tZtLj$d:BV;HTj[~:_8EC?[>]o[N^FJV^*cR*SK'vD6=9d;'QCEQ?^`XT:9-NBH?D;N-LW/G~:QeYJf=JkLGS=$qFnzQ8DNKLZMvE at A~5OaaWCY.85IJ&7C1~>U6OeAZNKSdHQNM`@?IAU:4\BO\Idb3]4v?rorGC<pH\GkMDcSRH]W2\nOfH~q31O'ZHV,HdV`>~TI~H~QMHuB3Maqk_N|P~~=
+ at S1_41
+TATCCCTGCCAGCTCTGTTGCAGTAAATCCACCACTTGCGAACATTCTTCATCAACTGTCACACTGGCTCGCGATGGCAGAAAAGCTCCTGGCTGAACAGCAACAGGCATCGTATTGTTGCTCCTCCATGTTGTTCCCGCAACCAGCGTAATACCACCGGCGAGGATGGACTGGCCGTGTGATTACGCTCAGTAATACGTTCGTGCACCTGTCGGTAAAAGGAAGTACAGAATGCATGAATCTGTTGCCCGTTGATATCTTCCTTCTGCCGAATGGAGTGTGAAGTAAAATGCCAGCAAATGCGGCCAGTGGTCCACGCTGCTGAATAAAACGCCGGATGTCTCCCGCTCTGAAATTAATGCTTCGGTTATTTGCACGAAATGTTCCTTTTCAAACCCTGTTGAATTTTGTTCAGCCGGTGCAACACACGGGAAGGTGCGCATCAACACCGGTGTAATGCCAG
++
+b~;~i_t~~psn^i^[~I~l&~gnUs~~E~~mm~02Dv~~~G`Zv~eE~Mxf~E/~i~~t}r~~Y~,bZmU={dL=OuM{~sGji~h~~KHY~;X;~ASBajJ~~C}~~~]VRh~~aUh8Ov]~fd~PX3 at gY/Y3E~~tw~~~[{^~~w~~7~wUGNUO~\|?H~~2~^vKQj~pKMAxs~Zap~|g~~|~~\~~Cx~w._~R~tq~p{g~YpEyX~F~V~~D~d>~@~b~Q~~~^f~~G~xPl~~tY~srmV~Q~m,~IOe^~[T[~~:~~g~*~~tYkO}<hJ;~~=o~8-~.\)\~lMw~yn&yA_~t^bdw\Ut6[Ky^La_XMkQ~~~~FL~~T~VwR~~~8FS~RaV_]e~cw<y[mV4yejNh]g~^~k~~aR`xb{~nE[~laa~~}~]~KoJX1~{~[{jk~~~Y[~~Q>u~S/sM~Tn^O~lj~GKaf~~~jp~t~OSFU~~kxRgEV~hg{
+ at S1_42
+AAGTCATTATCTCGACCGGCTCAAAACGTTGCAGGATCAGCTCTACAGCCGCGATTTGCCAACAGTCTCAAAGGCATTGAAATATACGGGCAACGTGGCGCTGCTGAAAGGGCGCTCAAACTACCTCTGCCTCGAGCGTCTCGAACAGCAGGCGCTGGCGGGGGGCGATCTGCCGGTACAAATCTTAAGCGATGTGATCCTCTGCGCTCCTGGTCTAATCAAACAGTCGATGTGATATCAGCACCTGCGTCAGCTGGCGGAAGATTCACAGGCGTGCCGCTGGTCACCAGCACCAACGACAACTGTCTGGCAGCACTGCCCGATGTATAAAGATTGCTTTGTGGTCAAAGCACGTAAAAAAGCGATGACGCCGATGTGGTGGTGTAAACCATCATCTCTTTCTGGCGGATATGGTGGTTAAAGAGAGTGGATTTGGCGAACTATCCCGGAAGCGGACGTCATGATCTTCGACGAAGCCCACCAGCTACCGGACATTGCCAGCCAGTATTTTGGTCAGTCAC
++
+p~chf~XXt~EOJre~FIg~iz~8~Kw~I~Yhk~~~Y79~~~F~Xpcbi|J~[~~3~d~~AEU_~/GK;L~w~~HLZ[^r0k\GQ~I~I~yR~~t~~jv~ehK[RYV[cy~Q~~\~~U~~~e~~HWk~~~_SLn]NwwX~<(:~~`~]zV7cj~Ux,oUrgc~b~~uK^~~O~9~XPfdy~h at SO\zP|~~HF`[y]~~jbq~Da~Mu~uU|BG~>gGV~t~~j/KJ^~~yXY]L~~\Z~~^O~V|~~q~dMrUfsdu~ZF``dlp~\~5~da?<}l~OCix<~~leF~~P~HtT{~L~xO{@_kH~8{~~JR~+~VR7~O4~Fw~~]~\~~1~~m~~]c[;rq~^i~tY~r[`h~~9C~`~ib~L~U~~~7~;_~bzs~~PJ>_xr^f~E~[_9~onB3a~<Cvet~~~u~Mn}\~V~c~tV>~C~Yy~[~oL~L`l~VV^~S~qrzvX@]~HOz,C~y~~TN~MHOi~g~UH/~htaD|US]Ld~MYYt~K~H~~V~ZLN~PZ{~~8]~iv~~~^x~}~
+ at S1_43
+TTCATGGCGAAACTCTTCTTTGACGCGGTTAAAGCCGTTACCTTCCCGACCGAACATGTCTTTCTCGTCCAGTTCCACGTCGTCAAAGGTGTTTCACAGCAGCTATCCATACGCAGACCGAGCTTTTCAAGTTTGGTCACTTTGATGCCCGGTTGCTCATATCAACAAACCATTCGGTGTAGACAGGTTTTGTTCGGAGAAGCCCCGTCGCGCGCCATCACCACGATGTACGGGGTGTAGGCGCTGCTGGAATAAAACACTTACTACCATTAAGATAAATCTTACCATTTCTACGGGTATAAGTCGTTTCTCAGGCTACCCACGTCGGAGCCCGCGCCCGGTTCGGTAATCGCTGAGTTCCACATCTGCTTACCGGTGCCGCGGAAAGCCATAATCTTGTCGATCTGCTCTTGTGTGCCTTCGCGCGGAAGGTGTTGA
++
+;?<G8%)F;(i=\B+OHJPS at WHRPD?OR7<0yI-7~0QIC/=?G?CFA:?V3>':8?**v>Dk=e5=@=%^A=<>0TgEBLO{@2HIEK+Y?FUOY?B;-T7DD[9%.7FF:K\KUD=NF at Hl=T-87\E<M06:&A:A)7>J9:>A4-6MU5L6(1Q9*K_PRB?5;*IKH>=YIM=SR\\J/G71.&N2+&:WCK?1.?SLO5bO]Ib-ZU/~RJB[KE)NaJiP=L]Q0MU8^2=51;H'BL>;?5E@/GD)9TSjEM/&BgGN.d_FGEG-H<M=V:Pj7I%TBS2>E9?>EyB%`?FX;D;96(H+JO'XO(+86EH04=VM=<.H.KCNF3%15z5U.E-VdCA3+?H7OB;/R?.9 at a~%.=BHKJSP8[~5NPKR6;>k2K@;.WEYQEZ89MWe?K.vd-CK76U?W7>=:3J>'7941C??FH=oK@
+ at S1_44
+CGTTCTTGAAACGTTGCCTAATACCATGTTCCGCGTAGAGTTAGAAAACGGTCACGTGGTTACTGCACACATCTCGGTAAAATGCGCAAAAACTACATCCGCATCCTGACGGGCGACAAAGTGACTGTTGAACTGACCCCGTACGACCTGAGCAAAGGCCGCATTGTCTTCCGTAGTCGCTGATTGTTTACGCCTGATGGCGAAGAGAAAGAACGAGTAAAAGGTCGGTTTAACCGGCCTTTTTATTTTGTGTATGTATGAAGTACTTTGGAAGTATAAGTCCGTAATTGTCTCGATTAGATATACTGCACAACTTGTTTACAGTATGAGCAAACAATAATTATCATTAAAATCTTCTTGCCGTTTTACTCCAACTCCCTATAGTAGCGCCCGTTGCCACCCATGAGGTCAGGCGACAAAACAATTTGGTGAGGTGTCCGAGTGGCTG
++
+L~z~]~~~~O=~k~Jx~R+~W7~;UxMin~eiY~N|wHXZFIZx~T;~U~snzn_~~oNWAb~`X~~~{~1~>FO~IUuM~O~mlERTecnY~C~G~[~kUv?D~V~{YS~~Q]j~T~(~JZ-~ci~Utjoy~wlc}KB~b~~w at 2J[~~~~Tsf}~H~gb;~Z}c~Isv~([PbcRpm~j\em~}Q~~~<R~~[R_~^~h~~~:~/WWn:~~VZt~ZNo6Tp~~~5]~LC+~vt~ou~~~~a~)jP~taXxcxQal3m<~b=~6{t^<WP~-`s/~~mV~t~NS~sn~~t~ZeR]~~~~~~~~Em~~FR=~u~?~deLI^o~~+<~||[vp;[T~~~~~~pzpCkNm~^}[~W3~Fw`p~~~3GK~~Dgo<~~a~jsdg~~~|~tK?-ob~\Z~Sil1^~qPr[ui~P~A~_{b[9qM;~t5T~rUNDW\~xnR~K~sIPf~rFW~K
+ at S1_45
+GCTGCTGCAACGGCAATGAAGAAGTCCGCGAGCGCTGGCAGAACAAATTCGCTATCTGCTGGTGGATGAGTATCAGGACACCAACACCAGCCAGTATGACTGGTGAAACTGCTGGTGGGCAGCCGCGCGCGCTTTACCGTGGTGGGCGATCACACCAGTCGATCTACTCCTCGGCGCGGCGCACGTCCACAAAACCTGGTGCTGCTGAGTCAGGATTTTCCGGCGCTGAAGGTGATTAAGCTTGAGCAGAACTACCGCTCTTCCGGACGTATTTGAAGCGGCGACATCCTGATCGCCAATAACCCGCACGTTTTGAGAAGCGTCTGTTCTCCGAACTGGGTTACGGCACAGAGCTTAAAGTTTTAAGCGCAATAACGAAGAACATGAAGCCGAGCGCGTCACTGGTGAACTGATTGTGCATCACTTCGTCAATAAAACGCAGTACCAAAGATTACGC
++
+CBLSCF\=1+w'BWLAg+fN8BNB^A-U at UQ9KC@5@=[ENXb8.%K*@$QITZB/<Ed/N.>@G4s?C7;9/8UEGEg'[/JM~CSK*1237Wa4(]FZ283GB%C.\AA3FBY]uLG>5MD?dRGpMCW7N>4FMK&ICBQ+j)p;/^';$E+d>I^AC2&HDE597E8,)?1=@A%Y>(5>b8<J8G/0NBMH':7GTBJ772c$GdZ<v at L:'>aH=?M at XR*8,H59.UUI=PJcM[:,<<=L-H<O'?68EGCt6(8IY-;FW<De72>[T+f9K:'+'F;FD3E-5Q. at 7?~A+WNI>0YEDURFB5HB0;+zAj,~/3O<[01k}YfL=U9YK?QCG@}+M?*D>0XBH~3D0;UA4Q3X~?O'4]DP=C5 at 98;HL4A<4G7I\+. at 69;E&@FEKA<'<VQF//F3H&C3H,PY1XJKB<GU.4?PH+3;_gY>+AEKB?TAAHKbV
+ at S1_46
+GTTCAAACGATTCGGCAATCACCACACGAATTCCAAGCAGACGAGGACCTTTTGCCGCCCCAGTCACGGCTTGAGCCTGATCCATCTCTTTCCCGGCAATCACCGCCAGCGGGTTTGTTCCTGCTTATAGCGCATGCAGCATCATAAATAAGACTACGTCGCTGTAGGTAAATGCCCGCGTCATCCCCCCTTCAACGCCAGGCACCATTTCATTACGGATGCGAATATTGGCGAAGGTGCCGCGCATCATCACTTCATGGTTACCACGCCGCGAACCGTAGGAGTTAAAGTCTTTTCGCTCAACACCCCGACCTTTAGATATCGACCCGCTGGGCTGTCGGGCTTAATACTGCCCGCCGGAGAGATATGGTCAGTGGTGACTGAATCCCCCAGATTGCG
++
+?~P;-mBV]_)lHPxaC-bj~Pbsd2^L~`K=^~2NP0h at PReUd\G3MjyL2Z/mMc(KPLE~77;W<\TZBHB04FmR<b]ALb6WBkbO(4=8>3N5d1bb;bR~6J at Cs~BFK4ZJ~Ly~QhdLv~R[0-<~f^xyk9z^etb~~LGWr~S8f4D\3S6mU~eJLK-CRZ^3SO`BY5VBe=6U~J)2\8XEkLLCT>R9p~~;?[:pOalDZ~VY5WLeN5hEB~Ek<p\cpXX4.eZBCQR~>sE)@OQ]UG`TF1K at Y8'ANY.A<LPL[d7uZLy{~LGAPhjTrBgA6i?ENBSIKfk6U~%B7WxbfA+E3TvZSKXYBp\MmBmC1\IYH6XNMR~BQ$DVT}&:GYQVA at f6?Y5~2>H;E+GNDFaj/c;W\<Ocj`74\ywxC$w
+ at S1_47
+GACGAGATAATAATGATAGCTAAGTCATGGAGTTACCATGTCTGCCAAACATCCGGTCATTGCGGTAACAGGATCCAGCGGCGCGGGGACCACCACCACCAGCCTCGAATTTCGTAAATATTCGCGAGTTAAATCTGCATGCAGCTGAGGTGGAAGGCGACAGTTTTCACCGTCACACCCGCCCGGAAAGGACATGGCGATCCGCAAAGCGCGCGACCCGGGCGGCATATCAGCTACTT
++
+, at N'DJ-4?0/K2SF248)+&@$AH?4 at 2637U)2D&9.9C/7J/20<<,96J2.;';3,D86C;@6516NH?.DP2G4W'?6A(64*'9(=C87-0K;:4:0GB)E+$/IDA*;D:B at 52C(+232<(@[/)/+=+%;J'89C=,=%O-6'&9V4=)BAE:C?;Q59A%6;9%6SPH$>F.9I99(.6EA(-:CC9.3*/;@:5P:4F3F at 356G@8G-,=03&)-;):84,/P3-2@
+ at S1_48
+TACGCCATCTGCCCATGCCGCGTATGACCAACACCTATATGCTGCCGGGTAAATCGACCCCGCAGGAAATTATTGAACCGTTGAGTACGGATCTATGCACCGAACTTTGGTGGCGGTCAGGTGGATATTACATCCGGCAAATTCGTTTTCTCCACTTCAGAAGCGTATCTGATTGAAAACGGTAAAGTAACGAAGCCGGTGAAAGGCCGACGTTGATTGTTCCGGTATCGAACCATGCAGCAGATTTCGATGGTTGGCAACGACCTGAAACTGGATAACGGCGTGGGTGTCT
++
+Mm<CZ]7Wb7?=]?ZP4NuT at UFrO3T~FP=d4HdNfwkS_bNL~:[fGTITv^=JeNFl]AWeWK$K.R]c/>~.3XkK~@(lZ=~=ZE-ICZwzgW1n=dG@\D~c~R>sP?L=9KIQMKX`gBHWsL>e at S`~TMKQ)X9QTTLL_R~z~FYOU.jN>.~KE`4y>P;~rD=MUXy1=U~o~G3Q7z`EZ_N^>SG8fP1[QBqmVOzP7V6/~=E4h/J?PV~]<Cj\eV7.U~v~OgLFKC67<J>~<F?[~p8j;ZBZDH]V4VRD:%WD~_8<nE<-H6^E~mpm
+ at S1_49
+GCACTGGCAAAAGAAAAATCACTCGGCTTTGGCGTAAAACTGACTAACACTCTCGGCACCATCAACAATAAAGGCGCACTGCCTGGTGAAGAGATGTATATGTCAGGCCGTGCGCTGTTCCCGCTCTCCATCAATGTTGCAGCAGTTCTCTCTCGCGCCTTTGACGGCAAACTGCCCATTTCTATTCCGGTGGTGCCAGTCAGCTGACTATCCGCGATATTTTTGATACAGGTATTCGCCCTATTACTATGGCAACCGACCTGCTGAAACCTGGCGGCTATTTGCGCTTAAGTGCCTGCATGCGCAGCTGGAAGGCTCCGACGCCTGGGGACTTGACCATGTTGACGTCGAACGACTGAACAGACTGGCAGCAGATGCGTTAACCATGGAATACACCCAGAAACACTGGAAGCCAGAAGAGCGTATTGAAGTGGCAGAAGACCTGCCGCTGACCGATTGCTACGTTGCCCCCTGTGTTACTGCCTGCGCTTCAAGCAAGATATTCCGGAATACATCCGTCTGCTTGGCGA
++
+~wGAi~~I`f~y~~V~~w~;~yg~W^W~glQP~\XO2T\N~U~S~ED~l?~Z~,>~_]^w~^~s~~~jMH~}LZ~Ld~~~yx~Iy~~~T?d~d<k~~YP~Q~``QB[d|~KZx~g<~Lx~3@~S~\K|z^`y<~8<{JU[JPdp~~ay~:p{~a~~m~U~~{u<fd~~sK1l^f~\JV~/Zpf*~]~W~~4~lx~~?~{dy}~2IuJW~J@~iY~3|rAzeEb~~Sku~M;sx~`~Mn~<g~~~4~ohLxHumo^>q~}X~j~i@=<T`~Cxa~`cj~}{]s<~JP~j~w~~~fR~lWT~~G[J8jqmQT~q~9f~6N;~~~ykYzku~nYg{yvh~~3I+~~~~~bxHgo~B~Taw~1\ADs~mPSfN9sN~Y~dT0@`TbH\`K~3~nJ~y~oM~qx~`/~&Z~d]~Xm~~dGCtz~YO~EwqdrC~(4M0~MEc`T~g~~M~~;tj~~h~r~H4SRsT8o8~kJL~MF_~~[~h_G~[~R~bF~P^9~`~]dt~^oo[}~?X9~oc~YnnoQ~e4~s?m~~~~YnF~
+ at S1_50
+CCGCAACAAATCATCATCCCCGCCACCCTGTCCTGATCGTTTCCTGAACGATAAATTGTGATCTTCGCTGCGTTTCGGGAACGTTCCCGTTTTTAAATTTTTCCGCGCAATATATTCTGCAGTAACCAAAATGTCATCTGCCATGGGGCTTATGATGAGCAAAATAAACCAAACGGATATCGATCGGTTGATTGAACTGGTCGGCGGGCGCGGCAATATTGCGACGGTGAGCCACTGTATTACTCGCCTGCGCTTTGTCCTC
++
+[/?6-L$@0F*1,JC:.%=9JIG at 2'CB+5N at U;:)5Q.WB2.G&ICD7.'.;I3B8:5<D/?-+UE8LK6=';G at GS4@(JF=A=B=M;T(,c01S:?6296G7'8@=@/>P:>>9D^4,;JF:>QLO\-,LSM/=E3XIQnE6>ECE2;7.G(?4=Q.X?GI=-<WK2;.-;LS<@,/6>~;I(\&&:DbTT6R(59:=I(A2O>CZB74C7C<O/bR?C;f,3;/=I(=@++7>.=<5JET.OO?(:<,(9A.,&JAJ9
+ at S1_51
+TATGGAATCAGGTGAACGAGAGCCATAGCCGCGCATCCGATATCTGGCGCGAAGTGCCTCGCTGTTTCGCCCACCCAGCCGGTTACCAGTACGGAAGCCATCAGGCGTTTATGCGGGTACCACGGGGAGCCAATACTCCGGTCCGTGGGAGCATCGCTGACGCCCTATATGATTGACCCCATTAATACATTATCAGCCCGTGAATATGACG
++
+~`v~N\Wn~~e~aOPz~crO~~lhiir]/~~~~Z}A|~aN~w)~uPbtb~q`kD~+^RI_~>Kv`vh~r{4JX5F~2mkdX~~t~gtF~~VdtQ~~~Z~c~xq=|h~g.U~BHk~~~?'ht<~OVY~Fb~ZaR}g}JQJ~i=7v]jVF]<_~F~~aK~Xqk`~~?+b-Rq~~b~E~;L{bR8^\~Zl~Ssal~~U~~~~~6reeHp~Mkys
+ at S1_52
+GTGCGGACTCTTTTCCTTCAGCCCAGGCGGCAAGGTATAAGCAACTGTCTATTGCTGTGCGTCGACCAACACCGTACAGGCACCACATTCACCCACGCAGCACCCTTGTTTGACACTTAGCAGTCCTTGTTCGCGGAGTAATTCCGAGAGCGGCGTGCCTGGTGCGGCGTGAAGCTGAAAAGCATCCCGTTAATGGTGCATTCGATGGTAATTGTCTCGCTGTGATTCATTGCAATTTCGCCCCGCCGCGGCGACGGCTTCGCTAATCACTTTTTTGGTCATCGTCTGGATGGATGCAGACGAAACTCTTTACTGGCCCGCCATGAAGAACGCGGGGCGACATCTTGCAGGACAGATTCGCTGATAGCTTCCAGCGTTTGCAGGTTTAATGGCGCATTTTGTGCAGTCTGTTCGGCATGTTGGCAGCGAATCGGCGTTGGCGCGGCAACACCAAATGCCAGCGTAATTCGCTGAAATTGCCGTTATCCAGTCGGCAATGTGCGG
++
+`v0~~~FRi.SFG~G~\U.^/^DOM?k`06Wf^[bKFi~spB@~~TsHzX6~5J=RV`)ZSH='1~L8PK'6J at 1IRYNM,T:9~/JEfK]4Pz6TURKj~L~6I^>Y7[8:C~C~.J+SR`Y2HaH~Dfh~~N62?,_F^T=^S=]FUMw;>R at TEVCFJhF4D:;P=vRy>`GcYd7B at _KLDH`F~*I7k^>9q4Hd]XJy7bJcRA/e~=~%S\0CLLIC<E:bJ at Rkr~`~Mrc(8Rfi_NiE<UTV/\V~(NK9L\~EZL-8FhnM3IChojl.L:I?l^qT?E^X'K[Jq^A>B7I1OIsH at _9IVAFM~>.vPNBAx~XdJV]I^5M~N2.LQvj9:;U7HH_Ul&lN[?Bhi~?CdI~C<]]]VBla:<UPAFk6/JT_VRR<AN;-U7,cjMN<`0Xu?A9=C[DF5Tf^oGU7Sc:;Vx~LHKF8>~_:~TF~CW)H~hgguKXM{PGQKD\gL,YX_Ie[[9X~NIG;>;[hDF%?oG`DXL64>NM~TAWC
+ at S1_53
+TCGGTGCGGGAACATCCGGTCGTCTGGGGATTCTGGATGCCAGCGAATGTCCGCCCACCTACGGCGTGAAACCGGGTCTGGTGGTTGGTTTGATTGCTGGAGGCGAATATGCCATTCAGCACGCGGTGGAAGGCGCTGAAGATAGCCGGAAGGTGGTGTTAACGATCTGAAAAATATTAATTTAACGGCACAGGATGTGGTGGTTGGCATTGCTGCCAGCGGTCGCACGCCGTATGTGATTGCCGGACTGGAATACGCACGCCAGCTCGGCTGCCGCACAGTGGGAATTTCCTGTAATCCGGGGAGTGCCGTTTCCACCACCGCCGAGTTTGCCATTACACCGATTGTAGGTGCCGAAGTGGTCACTGGTTCTTCGCGAATGAAACAGGCACAGCGCAGAAACTGGTGCTCAATATGCTTTCCACC
++
+wTYg}]D~i~mH5w~~~7~~eWVpPR}`-~Yb~`~u~~s2z~~~nzlh~IX~P\hc]~s]~~~~YeL~Qnxzfq\~-yT~q[a~e~Q~~~Kfj~/rLMP`jw9~OLk~sn~L~~~D~~~^n~~~qvb~~`~X3~7'~Z~W~fRl[~wB~mSS`=?~~UVUzO[f~Jfxhe~G~~y1~VDvsF~~N~jy~~~x~~Cg~[~P~r[hY~iQ:_~xjhLfNe~LQqr~K~~F~~EsSe?oQ\~9~_fQ~xf~B].B~tv~=u~~i~S~[B>[dv^J*~JyguU\~Vdez;Z~eB^~~tf at gYM~~p~~L~Hy_a~~}O][7f~hZ~O?]e~~~F~~f]awFZ<W~~N`~Zjv~ED~AA~Qm|<?pq~0~~c:6T[~Ak~|~dW`ZL=NT~bqggx~9Mt~~3~~WG~IcusU~~dJ~j\BXmdn+~\~7~
+ at S1_54
+AGCGAAAATGATCGCCATCAATCTCTACAGGAACGTTGGCCTGGAGCGATTTACTGCACCGCAAAACCCGTTTGAAATGCTGACGAACTCTGGAGACTCAGTTGGCCAGTGCCTACTATAAGTGCGCATTGGTGGTGATATGGCGTTCTTCAAGGGGATGATGCGCCTGTTAATTGAGGCGCGATGATGCTGCAAGCGCCGCAGGTCGCCCTCATTGTGGATGACGAATTTATTCAAACGCATACCGTCGGCTTTGACGAGCTACGCCGTGACGTTTCTCAATTCCGAGTGGAAAGATATCGAACGTATTTCTGAATTAAGTCAGACTCAAATCGCCGAACTGGCTGATGCATATGCCGCTGCCGAAACGAGACCAATTATCTTTACGGAATGGGGAATCCTCAGCACGAACATGGTACCCAGAACGTACAGGCAACTGGTCAATTTGCTGTTGATGAAAGGGTAACATTGGCAAGCCCTGGTGCGGGTAATCTGCCCACTGACGTGGTCACTCTAATGGTACAGGGCGACCGAACCGTCGGTATCACCGAGAAACGTCTGCAGAGTTTCTGGCTCCGCCTGGGTGAGCGCTATGCTTCACCCCACCTCATGCACCTGGACATGCTGCAATTGCCGCATGCAGCAATATGTACGGGGCAGGC
++
+32>>2$>7&-').206&(+B)+58/'67860,)-)'./:/'*C<'/11@'007/)'2*)++5?:M/>7<%(D+0:.*5*(8640')3L8'4!81:&@%:'&,/6&3.,)40B5/.8AD'6.66();3/<7>+-,@/<57%*2F=,7B*%%>/&@?380$B)?)130+/0-:6<'>(<)7=3354<2*3-3>=0/7.*F96, at 71%BF*'6/64&504<.,.+)*%?3,=7,1D$$JCG*&55&4%&&M?0,5'1*1.(94)&((0(1.07;'6+&&,(&3D.3.*9>D+K30/%D=)0441/&)%(4-56+4/:-5@*42*1-L2,=&80%++':+4/C+0)*=-3=4(:(7,07*'3+<.+'58++-6*A(91-'/*&2$3+6%-='?0,5895;%?(&(/2?@+.-0;*;.<<8(&=/22%4,6/64?'&-5-4=7+6=1<*-6G;')*4743.,I%+?(63'O)-&:$A,*)B+((---,.F>95=(*',>68>=&BO&=,,.3227*)/2B8/7-+=3.1;/*7+,L57=?-4;*0>/$5-D-86&-=F'7:1 at 1(20947%,,<<'&5(7D&&68(.C'16*MA7112+/*+7=0 at E?3'412%341C3D:*)((+4G:*9$1<*-93*,K<;1*8'8%6%;++,91A85(=5L6*,
+ at S1_55
+TGAAGCGTGGGCCAGTTATCCTGTCCTCAAGCGTTACCAATGCGGCGCATGGCGGATAACTTCATTATGCAAGTGGTATGGATCTGTTTTATGCCGGATTCAGTAATAATCTGCCGCCGCTGCGTTTTGTGCGTAATCTCGGGTTAATGGCGGGCAGAGCGTGCTGGCGTGTTGAAACGTCAGGCGCTGAAATATGCGTTAGGGTGTAGCCTTACAACATTGCCGGATGCGTGCCAACCGTGGTCGGATAGACGCGGCAGCGTCGCATCCGACATTGAAGGATAAGACGTGTCAACATCGCATTCGACATTGAATGAACGCAGAAAAAGCAAAAAGTCGCCGAAGCGAGCTTTTTTAATGTGGCTGGGGTACGAGGATTCGAACCTCGGAATGCCGGAAATCAGAATCCGGTGCCTTACCGCTTGGCGATACCCCAACTGGGCGCACTTACGATGTAAGCGTCTTGAATAAATTGGCTGGGGTACGAGGATTCGAACCTCGGGAATGCCGGGAATCAGAATCCGGTGCTTACGCATTGGCGATACCCAAAAATTGGTTTTCGAATTTGCCGAACGATT
++
+3O$43K%>.8>$:.C?82K=</)I'P8DA3*K2+27(3,1EE2.)+?4/=DIJK;@>+;/0?-;F8)M='&1J+1B(&-27B&,@<L.917D'=/>Q*55,7?)4%H7DFD1>F8.8.-(9>>4*ME)(11/9%*NC%.6='A+?'3%0:);&B@,9;';>3</+@!A:../(A4BC9BFG>/I0&FB=K-3(D4%44AM4AR793'3><%:20742+OT(,*KA8M,I8G)0F:D/5WL'%8,(B95M1,B6(8&;7-1Z)5'RAH%-=?&>&.:;9A:EM+)&>*5L)??XJA@>7@>+08<2?-L0S1*?6.9J+NF/74&4,AG523:;F.K3.=<-N9>-:.H8O9A.LB5G311>6=)(HB6H7G).6:-CB)29=FA46,0C/:1>04:N.&E7L?>,1FAF@)55 at OB$+EC,.I=81//11GA%<7S>*@3H<B)-9>-69B<B?2)C3**5%>65N-+)P8A4(F;42BEI;8>2;:KO?D, at 94L8;F43,,@/C35,,1(9::=-K;L=6*,A1*1H$>/,E%-6+<;)K7<8D(8A>.5I*4>58!21637)3=91),4&6C20I
+ at S1_56
+GCCAGTCTGGCGACCGCTGGCGCATTAACCGGCCACGATGTCAACCGTTTTACTGCCCGCGATGTATTTAATGGGCAACCCGGTGCAAAATGTCGGTCGCTGCCTGGGGACAGCCGAAGTGAATGCCAAATATTACCCGCATATCATTACGGTCTGCGAGATTAACGCATTGCTGTCGATCTGGTTATGCAGCTATTGTTTAACAAGAGTTAGCCATGATTGATTATACCGCACCGGTTTTACCCTGCTGCAGGGAGCGCATTTGTATGCGCGGAAGATCGGGGAATTTGCGTGTCCTCGTCGCTACGGCAAAATTATCGCCGTTGCCAGTAATATCCCTCCTGACATTGTACCGGACTGCACGGTTGTCGATCTCAGCGGGCAGATCCTCTGCCCAGGTTTTATTGATCAACACGTCCATTTGATTGGCGGTGGCGGCGAAGCAGGTCCCACGACGCGCACGCCGGAAGTGGCGTTAAGTCGTCTGACGGAAGCAGGCGTCACGTCAGTGGTTGGTCTGCTGGGCACCGACTCTATCTCTCGCCACCCGGAATCCCTGCTCGCCAAGACCCGTGCGCTCAATGAAGAAGGCATCAGCGCCTGGATGCTGACCGGCGCTTATCATGTCCCTCCCGCCTATTACGGGTTCCGTGGAAAAAGACGTGGCGATTATCGATCGCGTGATTGGCGTGAAATGCGCCATCTCTGATCACCGTTCTGCCCACCGGACGTTTATCACCTGGCTAATATGGCGCGGAATCCCGCGTTGGCGGTTTGCCGGCGGTAAACCTGGCGTCACCGTGTTCCACATGGGCGACAGCAAAAAGGCGTTACAGCCTGTCTATGACCTGCTGGAAAACTGCGATGTGCCGAATAGCAAGTTGCTGCCGACCCACGTTAACCGCAACGTTCCGTTGTTTGAGCAGGCGCTGGAGTTCGCGCGCAAAGGCGGCACCATCGATATCACCAGCAGCATTGCGAACCAGTCGCCCCTGCCGAAGGTATTG
++
+KDfj9/_XZiO9@~~L~~>a8l'W[HjC4's at E[e<MAQ94-C,$~N~zIJaAKIYP@~E~hR~@Gr[UJR[Lh^;M}hIE@:CHQ~VNU~L9OLHkFc<`ET=o*GF~<L~9T~Pl~8FA0e6B@>jD~%-)T~UU+~B~5A1[ADAu9TnzH~=Fr)Gn_6U.0>XfoX_~vPHnQVNZ>FTD*NHx?]N~i4^UD5J;_okG6>?WiJD,`V0O5KJE:s&[~LD~RKnD'\Y7yU`M'0>NZB~N\5Pk~QQZ\RYB[AB\~XhT~S,~WA<*@pO~~,NZC`G~C_A~~A[XtO?me~RK~LL<EZ6C]UY~0']G`Z.^|LHgZEIN%~W~H4jJNYZ>~Fz*2FHh*9B~TGMBHn_HOH-U<o$H at IS>M>@QRE2DM/~-7:*N^NT at mVi`>i7L at JY[FV~U~(u61So<]sIKH~H~E~JPa@[\X17\Z0DFdz:SN)M=xnF~R^YoH168DPRZTYH~LI+ at D<fd>C\imaQJ>>$S~iJ&F~IXGNGepH_<BB[=AH)6mC@/>@V=d-y8^DO3dkTY~FS}DA7RFmY>8xAFoU at YG:OeL~q~R=W>@=9Q:A5O6NJ~IH&~~@G.6SkRSK at lVn0Sb=6W;>8BJQ~d|~NVyRH(8?DJHQB~6.Rq at IPJDGI\VF>A'\p|~A~4<~ORNNATQQ<NyJV?b'W62lGfB@^?=H,HEQ|f`u6$KCNF[6B<iw%w`H\'E:~PP~USAA4%9=%S=OVUEtO:PPbBq=~=F~KTY,oy~~W9oWK0l.Z;~<+L[PKC\:NahV/NHyIHo+P^I~O@~<7XGmgaH~-27PR~mU9 at OAU5~7QHb/FM@;iD(G/I.5<;F^h=EZJQ~(W~l<*F at Gf<PGMA]PG`VAW~~<8~lBQOCuKldL<)P\y`bH~NwF~@DDwB=,~-DAQD9Zn~laZH<T7~Zj:DugQ>7L=D><1?KE?C^4~SSE~_wcJDVRUOHoK>EV??d&K~FH~.=pV`=C>h0V8I<LVAE.MVYZl<J%h^IaOSGi-Q6A
+ at S1_57
+CCTGACGTTTTCCTTTTAATCCGTTCGTTATAAGCGCTGATAGTTCTTGCGCTTTTCGTAGGACTAAATGATAATGCCCGACACCAGTAATCGTTATTGAGTAAAAACTTTGCATATCCGCCGGCCAGGAGGGGATATCTTTCGCGCCAATGTCCCCTTGCTGGGTTTGTGGAACCTCGATGCCTTTTTTCTGATACCAGTGCAAATAAATGGCGATTTTATTGCCGGTAATGCTCAGCTGTTTTTTCCGGCATGCTATTGAGCACAATATGCATATTCTTGCCCAGTCCTAAATGTTCTGGCTCGAGGATTTCCGATGCCCATAAAATGATTGTCATGTCCGGCGTAAATGCCGCCACCTTTTTA
++
+:02-&+//.?3-689)1$K-;@&+*3:F,.:';-0*A*5,03$(+9-((6:,B>3)0.1(',3+H%1 at 413'%3*67@:)A31=0//,(+9*?-0>8,(-:7/)5%<-,E232$:./)O2/9'-0A3)+82.:,3068(,76=+%5F;)F75&;-28+7-G37:*+3?$83&:/-;',L,57+7=A*4)+,1)J5/4*6HF*&968A'.A.%G"'<A-90B&F(%436*352;75<:3B)<6*;%,"-E9:@<'.*8C>,>>;7A:>7-)>2=07+'83&1.,617 at 3$(=+%%B,;)$2-+&3%(:(=.278*.3@,(,0.2<.;(2-1&6'1*(5%4<9(31-C'444*&E'+7A.++*6,,12
+ at S1_58
+GCCCCATTTATCTTCGGTTTCGCCAGTGAAGAGGCCGAGAAGGCTTGCTGAATGGTTTGGTAACCGGGCCACAACGGCCTTCGCCAACCTGAATACCATCTACACTGCGCACTGGGTGATTTCGCCGCAGTACCGGACATAACACTTCATCCGCCAGGTACGGGATTCGCGCGACAGAACCTGCTCACGCACTTCAATTCCCAGCTCTTTGCCAGTTTGATGATGGCATCACGGGTAATACCCGGCAGCGCGGAGGAGGTGAACGGTGGGGTGAACAGCACACCATCTTTCACTTCAAACAGGTTTTCGCCTGCGCCTTCAGAGATATAACCGTTCCATCAGCGCGATACCTTCCTGATAACCGTGGCGGCGCGCTTCGCTACCCACCGCAGGGAAGAGAGATAGTTACCACCGGCTTTTGCCGCGGTTGGGATGTGTTTGGTGCTGCGCGGTTCCAGGAGGAAACCATCGCATCGATCCCCTGCTCCAGCGCTTCTGGCCCAGATACGCTCCCCACGGGA
++
+~i/w~M}UGm~~/~oUC~j~B[pPK~~0L~J~i~_8G<Y4^~~_~Yyp~~T~5s~~mw~hvIQ~~_~~Q2~s~n~f~L~a~~V~bG~~m~O~~P~zs~c~pRMo~~~aCs~~O~z`~mFYLDS~Y~`|uthM~dk`^@qSeK~y2y8~~~C~9FyG~~r]c~Z9W~Py~~|]~{~~Y~mUnaMrltiic~wx~~f~~|bfR at t~~_~~~-~mb~~~dL~x5v<~pkiF~}rO~~JW\w~[x~y~sno~~nQl~VTkqlxmP~k~~{4X>~b~f<m~_~b~OxbI~edU~~qM~B~~m~~td>Y|~vjWV~LS[rL27uW~fx~Y~g~UOn~bu~AX\^r`Wmx`~~b~OgjzEU~~~a~~~k~[S~w]FP~MkMqb~~G~fbvq|INMn?zisot~YROdQ~u~~NJ|~<xag9~~~~~k5m~a~`SMaP`v~~H~~=Y~F~Ds~xWksJ5a~s~o~~jL6|q~e~uO~~~~y~UNbZ~.hkN~F~V~~~~webu}G~~}~~]Fo`B~~~~PC~J~~OzZ~
+ at S1_59
+TGCTGGAAGGGCTGGGATTTGGTGAGGTTTCGTGCGCACCGCTTTGTTTCGTCTTAATAAAGAAGGCTGGCTGGATGTTTCCCGCATCGGGCGACGCAGTTTCTATAGCCTCAGTGATAAAGGCTTGCGCCTGACGCGACGGGCAGAAAGTAAATTTATCGCGCAGAGCAACCTGCATGGGATGGTAAATGGCTCCTGTTGCTCTCGGAAGGTTTAGATAAATCAACG
++
+TNA>]X~HRMUDM|?GXvUJ~C~`ggP<~=C at YQK5yJ=<UdM1KJ93+_N~_<^R~~KWp^pQ~*WsKQ1a.AQMYZRJJaIo~iJ~PSSIC;XB<~oVP~4SvW.CDU[LGeDDFK~n~@A$IuBSrlu8c~\[VM~W0He9;5:OAgGA-F~K~@\RfUZTDH~WiYBU,1MyrFJ8:N5wQ2.N*`*iG\8Ydj'FOCYA1j;~;Ce+Ou~-~~P]LBQeZY<<
+ at S1_60
+TGATGCCCATTTTCCCCAGGAACGCAGAAAACCCCATCTCAGCCCGATCTGTGTCATGCCCTGCGCGGCCATCACATCAGTGATACTCAGCGCATTTTTGACGTTGAGGCCGATGCATCAGTCAGGCCGGGGGATTTTGGGGAGTAGTATTTCGGTAAATCTTCCAGTTCATTTTTTGACTGCCCTTCAAGCATTATGGGGTAAATCTTCACCCCCATACGTCCACCAGATACTGGCTACCACGAACGATATTGATTTCATCAAACTGCTCATCGTCCTTAACACTCCCGCATGCGTCAGCGCA
++
+wyf~~~u~`DSXbYke,~~Q~F~L}M~~~mpZM~8Jnd~~m>-~_lMK=~_~~M~VH~=~]aIYP~Sm`?T~~7e?obSv[a^~]WOi~UZ1|S[{O]O_ORBFUn~~~QQ=as~~{MTnQ\p|^|[\3Y~Rn~G~GDb~Cb~j~~6Qy=~~bEnooz~r~vrWci~os<NggE~7q~UQ~~~7~Nsh~i~r~O~Bg~c~~uY:j;A@~\@f~~i~~~ElG~E0~~DLjm-?~C~dI~k~Fs~<Yh~RFs~SCyU~aJ~}fmm`wd~oODBCh@~~[a~f~[~~~~eJ~OuHkIlI]Fh\RqQh
+ at S1_61
+GATCACCATCGGCGTCTTTGTGCTGGGCTATTTCTACTGCCTGACGCAGTTTCCCGGTTTTGCTTCCACAAGAGTGATCTGCAATATCCTGACCGATAACGCTTTCTGGGATTATTGCCGTTGGTATGACCTTTGTGATCCTCTCTGGCGGTATCGATCTCTCCGTCGGTTCGGTGATCGCTTTTACCGGCGTGTTTCTGGCAAAAGTGATTGGCGACTTCGGCCTCTCGCCGTTGCTGGCATTTCCGCTGGTGCTGGTAATGGGCTGTGCCTTTGCGCATTTATGGGGCTTCTGATCGACGCCCTGAAGATCCCGGCATTTATCATTACGCTTGCGGGGATGTTTTTTTGCGCGGCGTCAGCTATCTCGTTTCGGAAGAGTCGATTCCGATAAACCATCCATTTATGACACGCTCTCAAGCCTTGCGTGGAAAATCCCTGG
++
+Qh~l~j~>~Y_~~_~^M~{;~t~A~RO2dKAcb~~F8WN~rp~g~[~~8W~~~_~``@b~/VTc5~Z?Vkyx~aE]~~9o0p\}~~>[~U~~mN?\~Mb.~~y[Sn~~;l@~@bm3N_H9x?~~8~W~~hpaZ~l[Y~~^k~~tHla[}m_C`=:cs[~Ysnj~Z25w0~+Y~(~~YYA~wf~1X~Q~~~~amhD~jHUX3Uux:X`H`g}3~n~,S~~~~|RFJ[~{T,~V;G~~c?-~n~~g.eh5VK~~~B~~PjPfW~k\@OQkV+[~g~?UN[WgV~D~1~{+I~Sc~~n}~nN.[Xuq9}~R~Gh?:r~~Qaw^V~q~a~oIek~osnGx*~z~~Hy~j`n~~~~>~d~-[UJpp~FKaSrbPS~A_x~~4D^~<S{zf_e~d_H~S6~yVl~V~~H~g~qVr~BcMm at x~XPH}\G~_>\d^Ni~~wt7ELY~EM
+ at S1_62
+AGATTTCTCTATCCACTACAACAAATTCAGCCTGCGTGATCCCATCCTGCACGGAGCAATAGATGTATCCGTAATGCATTTTGAAAAAGTATTGTTACAGCCAGATACAGCGCAGAACGATAAAATGGCACAATCCAACAACAATTTTACATTTTCCGACCGCTTTGGCTGCTTTCAGGTCGTTTCAATGATATACTGCCGTCGTTAATTCAAAAATATTGAATAATTAAACAATCTATTGAATTGAAACGCTTTCCTTCTAATTCGCAACTGGAACACGCAGCTATGAGTAAACCCATTGTGATGGAACGCGGTGTTAATACCGCGATGCCGATAAGATGGCCCTTATCCGGTTAAAAACGTGGCAACAGAGCGCGAAGCCCTGCTGCGCAAGCCGGAATGGATGAAAATCAAGCTTCCAGCGGACTCTACACGTATCCAGGGCATCAAAGCCGCAATGCGCAAAAATGGCCTGCATTCTGTCTGCGAGGAAGCCTCCTGCCCTAACCTGGCGGAATGCTTCAACCACGGCACAGCAACGTTTATGATCCTCGGCGCTATTTGTACCCGCCGTTGTCCGTACTGTGATGTTGCCCCGGCGCCGGTAGCTCCTGATGCCAATGAACCAGTGAAACTGGCGCGACCATTGCCGATATGGCGCTGCGTTATGTGGTTATCACCTCCGTTGACCGTGATGACCTGCGCGATGGCGGGCCCAGCACTTTGCGGATTGCATTACTGCCATTCGGGAAAAAAGCCCGCAAATCAAAATTGAAACTCTGGTGCCGGATTTCCGTGGTCGTATGGATCGTGCTCTGGATATTCGACTGCAACGCCACCAGATGTGTTCAACCATAACCTGGAAAACGTACCGCGTATTTACCGTCAGGTACGGCCTGGTGCAGATTACAACTGTCGCTGAAGCTGCTGGAACGCTTTAAGAAGCGCATCCGGAAATCCCGACA
++
+:P%M&wU>IG_Cbi(TCG_b~~9mDFkHSOAK`~t`qO~BSJB/@~WPGH&%*9S-=JJN}IyZ3f9~)g~D??GM>~[C1\&4RTkM]A~GGn`KItIJ\.\X~06xaPyh~WVO?M[YKW_cNN>p5E~f3J</=~Z~PTaM?6Z;SGQ]\BOxaKOm_NHgVRTgRBadS@~PFWZV\~F8>j+Z~PP]_VAGsjsKgX~6UvV~A%B~~V28;he:G.TeZjpRIa]>7HD]BWGPXW=S~~J8P?~T~SHH8AXP&GK8^MR]4x~^AmD>R]/2X.XGF,]M%G~^K8mqT8TZ+A8C7:?YTBL@*6D3m(QTH at DfHr[Z%~2`A>,3F~MX~yp~_tbDwEUCBxfGd>`P}hB<_(~f~KL}1-VP~HQjJ9iI/G`RS?dN./Id1GEbPa[Te)gL7GBAOhWB<6iMFV~4I/UL8x~XYW~<HMV>iULEKeEEV9cYNLaT?G-G~[\GEGAJinUY<a\EC&Guo9S0DEXPIIT44DL8H\A>CSTM/~OE^m?T\OH%Q^A}kj_~l=c at r+:rE_1HLR[<8WNj8lRITP+:Ga3}~TpQF*KXNN_~b96VbTLVK^~_A*rEOZAL~7]DnmZF1JBiBHL,ZVHiF4SDi;WFRTOQK>RC0 at V7GtYV~iGY;LN?QbQ4Xq9>MWMtR_<F~P;-JiH6H_aR=~bL^D at H<HDH%NAC@:U{YN~d-FVJdHZ[/L8cMHpHMu_M5]MFSc~~BX`D\3LNL7<OC($a6T8S>T_D&{GT\EQ[~'\Y4:nB~`NBN>`Teqo^<F*<AHNY[)GH`b,RyVQVH+sl~G;M@*=82?D,Tc\~Pa4~PkQ;M3bhiHZc^QAZSKPGGQIZE4YRSaQ4Ue~bUMTKR~|&P;JgE};ZMBGOG_cX>ELfiJDKTsS:TO:iHRW[>PHYe^qoLX at Y[Z<Pf=YI3 at RILK?i~SPtfVRUFK=OfJrNgc%V~I(cFSrd~5FZYmS==kd@~
+ at S1_63
+GGAAATGGCAGATTTACTTAACCTGCAAAGCGCAGCAGAAACGCATTTAGCGCACTATGAAGACTTTATCCGCAGCATGAAACCCCGCTTTGTGAAGCGTGGTGAACGCCCGTTATTGCTGACGACCTTATCGATCCGCGCCATATGCTGGTTTTCGGTCCAAACGCTTGTTTCAGGAAATTCTTGATGAGTACGGCATCCCAAATGCCTGGCAGGGGAAACCAACTTCTGGGGCAGTACCGCCGTCAGATCGATCGTCTGGCGGCGTATAAAGATGTTGATGTGCTCTGTTGATCACGACAACAGCAAAGACATGGACGCGTAATGGCAACCCCGCTGTGGCAGCCATGCCGTTGTCCGCGCCGGACGCTTTCAGCGCGTACCCGCAGTCTGGTTTTATGGTGCGACGCTCTCGGCAATGCACTTTGTGCGCGTTCTGGATAACGCCATCGGAGGTAAAGCGTGAGTAAACGAATTGCGCTTTTCCGGCGTTATTGCTGCGCTGCTGGTGATTGTCGCTACGGCGCTGACCTGGATGAACTTTTCGCAGGCGCTGCCGCGTAGCCAGTGGGCGCAGGCCGCCTGGTCGCCGGATATTAACGTCATCGAGCAGATGATTTTTCACTACAGCTTGTTACCACGTCTGGCGATTTCTCTACTGGTGGGCGCGGGCCTGGGGCTGGTGGGCGTGTGTTTCAGCAAGTGCTGCGTAACCCGCTGGCGGAAC
++
+g~dObdE22Nn~e;~0lc^~P~w{g\~~ssq=X~8iRJk5\~~q~V^b~~W~e~\~5~zv^,f{~jK~df~pX]HMwj_C/d~fG~JK}~o:~2~`XzP~E~XNNPIshlgV~Tky~{rwTI}~KLSf~Q~~;:~2T;`k]~~C~Yl~~DS+S~vM~~c~~Lb~QB~TID~j~\_xc~gM~i~~as~9RO~C^~~^~Wu~LKR~W`o~@~{yXwfh&RlRP8D]~~~nNEU];V<[{v~lOiKVFa~~b<GwC/~v~UK~^P0Ph?Z~gIdew_~m~UPPZFuOH_~9x~~~~~~epB^8Rsiy~(~~UL~^WIqclLS~~~~~zjIQsX8t~Y5~Y~a]~~~Q@@c_T|ZNu9~9Z~9~EAX~`ZxiB~~3mq4vye~~~Y~kHn[f]_ISSd3x~dGw8~zqZ~O~~~c~WAZOwdz~~~~~S~g~4^b>E?yPmv~fsLV~T^~{rkOMY~,[rgFuvY}kKDj~~S~Zc~~fH~~~]D~e~~~eK}=o~k?~vqbG~\f3EPTS<J~N7zc~pP]j{O=djH^~i~6B~U~1hJUYA0jF|~4R~Kk\Ir~xj~Z~h]~`v~bC~eN~g~~~`~~Axed~5~OY~X?bz~r;S~~~QF~gss`~=Y?~~WUqWSzPn~a~Q~6f~~`~~~ReSvPY~W~gq~9w~~v_O5HN~~z[~~BZhCo~~~~c~_~aO~68OzOMfF^7>~^mbR~~[ba~~~U~^~~qd~`xc^s{i~~on~~~Ajb
+ at S1_64
+TACTGGTTTATGCCCTGATAATGCGGAGGCGTTTCTGATGGCTGCGCAAGGGTTCTTACTGATCCGCCACGTTTTTACTGGTGTTAATGGTGCTGGCGCGTCCTTTAGGCCAGCGGGCTGGCGCGGCTGATTAATGACATTCCTCTTCCAGGTACAGCGGGCGTTGAACGTATACTCTTCGTTTCCTGGCGTTCTGACCATGAGATGAACTGGAAGCAATATCTTTTGTGCCATTCTCGGCCTGAACATGCTGGGGCTGGCGGTGCTGTTTTTTTATGTTGGCTCGGTCAGCACTATCTGCCGCTTAATCCACAGCAGTTGCCGGGGCTGTCGTGGATCTGGCGCTGAATACCGCGTCAGCTTTGTCACGAATACCAACTGGCAATCTTACAGC
++
+*:3A*(.1>3*(6G7.<3 at 1G63,><H:I1;&<@:ACCF0,]34G<41A+4=4A<E-16*4D+':@D42?617;7+/G7%B<6--F'4-88;*65>.'G292<'N*-TB7$;H/:)*50)?C>D'I90O658:'39-:8AC13?2N;6+H:F7'?:@0<>8&%))35'>?C8BU%*?44G(?@::7J199BE3CN/,+(GF>-6>[:54 at 1/7DDD)9+6)M1/9'8?-:5E041S4=,95/C>)69SA65F- at I@:57B$=5('8D.-%9<&+)I4<H+H*B)F?E6I*%J:.A<@<<N5P37*7,0I(6C-/JD at 9(==G3/*+=G9)DW'Z/R75/407$78J)07,?M((X-%=E:A73;74;OB<+(*+2<E6>345(/0(.19)>(;C
+ at S1_65
+TGGTTTCTTCATCCTCAGTAGGCTGTCGTTATTTGTTAGTGTAATGTTATGGCTATTACGCATATTTTGATCCTGTTACTTTGACGAACCGGGCATGGAAACCCGGTGGTGTCTCAGGATTGATAATATCGTTCTGTCTCAACAGATCTAATAATTGCTGTACCAAATTTGTTACTAATTGTTCACCATTAGATGAATTTCTGCCGATTCAGGCGCTTCGTAAACGGAATCTATTCCCGTAAAGTTGCGCAGTTCACCGCACGCGCTTTCTTATATAAGCCTTTTGGATCGCGGGCTTCGCAAATCGCCAGCGGCGTATCGACAAACACTTCGATAAAGCGCCCTCTCT
++
+I5M`13D3IIEGB.M1F=1:D2'L$5M;0=M[G3<=<C2G<R>A at OI79>E(34OG>4024?0?H.$FJ2=5C>O2R2>5EFLUd4D%%935QQIC(7RM(SCDV)QM4;C=D=;14A24a;(OL8*PC>53;TR9`JG3G:3Y:B.BH8:G5</-JG?f4J21GC*3<JdGE2E,9KF.D.:=,*.;JCU@$/647N=H2='R2F&@*G3H;B4?E:['@P-@@SKNIL0>K1;(<<.>F9J/n)22\DG?+:BCL](/JFC/U+2O?M;I32<3ICWHL3KUB<A<;0AGQIQ9NB4T=0EEQD<ELQaD.IBG4FF1QMT7C8D'=<[=B11>9/F2(FPE>'\6H
+ at S1_66
+ATAGCTGGAGGAAATTATTATACTCTTAAGGATAAGTCATGAATATAAAGACGCTAACGTCAGCCTTTTGTCTTTTTCTATTATTACAGCATTGTTTCCTTGAACGCGAGGCAACAAAATTAACCATAGAGCAGCGCCTTGAATTGCTTGAAAATGAATTGTCGCAAAATAAACAAGAGCTGAAAGCAACACAGATGAACTGGGAGTATATAAATCCCGACTTTCGACCTACAAAAAAGCATCACGGAAAACAAATATAAATCAGCCTCGCTTGCTGAAATATCAGCGCATCTCCCGTCGCTGATAACATCAAAAATGAAAACGGTGAACA
++
+SfDKBD<QUC~Ez~TS34RO~gM~a~vGpe;;ULTTMN81afII_Z~QbP`KE>Iet&;Ne,X7>~KZKBLw2jDP@~c^NQ9QMAFG~>jN at NUL:`jS'C=ek>-3<hPH1YWPWZpUpK5iVK~ashFV6AJ~L<`W~C^bYGDD(rVUDKK{SKZMA_32~>*:HcN3b>lKRnLC_dua?/IPMe~KPbO?~AHG`m:@d~Z0ljGEF~1R^M1>AaGOPTLORPR)5KBsJ~Y~N&Di[35JArF at XJ^s~s5AJHB at fQj?<O{Y?>>y%E.ByHNBO~;>QBMZW^xL~MH;~CR=?Ng?OT>K~J[<GSIViRC=CyW~H~p
+ at S1_67
+TTCGGTAAAATAAGCACCGTAGATAAAACCGAGGAGTAATAATACCAGCGACCTCGATCGATATCAATCTGCCCGACGCCCATCGCCTCCGTCACCGTGTTTAGTGCAATCTGCAAACCGTAGAAAATCAGCAGCATCAACACCAAGTCCGGCACGCCTCGAATCAGCGTGGTGTACCCTTCGAAAATCAGCCCCGAAAGCCGATTTTGCGAGAGCTTACCGCCAGCGCCAATTAAACCGATGATTACAGCGAGCACTACAGAGCTGATAGCCAGCTCCAGCGTGACGAGCGCACCCTGTAAATAACACCTGAAAACCCATACAACATGCTGCCTGTCCTGTCGTGTGTGGTGAATTACCGCCTCTTGCTCCCTCCGGATACCCAAGGGAGCGGGCTTTCTTTCACGATGGCGATTAGCCACCATAAACATCAAAATCGAAGTACTTTTTCGCTAATTTCTCGTAAGTACCGTCAGCGCGCATTTCGGCAAAGGCT
++
+I3ASd`;C-:Q3~~\_Ch=TaO6V]HRIB>~H%=~PYgd\~/cW(>4(`BEOO9k~OIENFAkF;cSiDG@~J_F9YJ:JJMWwUMjgTqD{89~'WPjYU3W^Q~n>H^UOy at JOK~E*jFY[NV\7oAb=/8xTfNO=>7[72gGOOIPF^<^}P:a6IAD;H{a<JB3F5N<t)@IPWWR2QC~c:`rB]uK3gy~~vb~]A:VCI^O^G1et3PI@~B?\;YO\CMW=~VV?N@>T~]E*ck{SG*f0D_`<I~qIK at TIS>E.:@W5~Z7LPa+TcRHdD7~JeSf at d6FGDHI;U`BC:5_ISb~2-1n/vRM\7BXwG\~I1HBIkQZ~GJHXu3]~:D\.l;M~97T?gRUqXoBN7~>=2Ti~HBW at RF$J>MHGSZSI?sBoMAGE{BN~l-Z~D*<mG<~CX1W?_yU~eTRBkVTNtdMMioJksTJ~aI at 7<TFxNYTCA8Cf`mCXGM6xF?`~fqwC~9J;^Md>7H?H?Os\2t0:3;0J
+ at S1_68
+GCAACAGTTGGACGACACAGAAATCCGGGCCCGTGTTGATCCTGAATGATGCCTTTGGTGCGTTAAGCTGCGCGCTGGCGGAACATAAGCCGTACAGCATTGGCGACTCATACATCAGTGAACTGGCGACGCGCGAGATTTACGCCTCAACGGGATTGATGAGTCGAGCGTGAAGTTTCTCGACAGCACCGCCGACTACCCGCAACAGCCGGGTGTGGTGCTGATCAAAGTGCCGAAAACACTGGCATTGCTGGAACAGCAACTGCGTGCGCTGCGCAAAGTGGTCACGTCGGATACACGTATTATTGCCGGTGCCAAAGCCCGTGACATTCACACTTCCACGCTGGAGCTGTTCGAGAAGTGCTCGGCCCGACCACCACTACGCTGGCATGGAAAAAAGCGCGCCTGATTAATTGCACTTTCAATGAACCGCCGTGGCCGATGCGCGCAGACCGTTAGC
++
+R~~ubQ(;~v~~g:Dh~~j41~Kb|I~~yK|{~kV~jV~U}v>~|~Mct}ev^u98ms~~~^vRz|F~~~Oaf8Z~~j[^M~~oL~^hb>d~d<M~~X~eI~w_~~XrRb~b~~~J~~xN~@I`~D8ca~yZuVhdR~1g~~{~~N~UAWR;IJR<TUhd~~~jM4~brkzoUZj~W_~J{4P~MPxQU~{I~Oc~R~N~c~^g~y~0~~LS~K~~^h~wJdo~c~~z|~T~oa[V;[WwGS~~`~jn~VMF~kAHVtq~Y~~~Q~~::~~~Q\|u;L~2RG~~b~~~`dx~5SZ5~R@*Pn~P~wt~qnk~edl~Q_p`s~Av~Nz~ck~b~~vjZ,Q~okg,~~~~_QG~O~_OL~J_C~~~~NdFOd~~~UnfUbNbxZLvYZ~iH~~Rwc~PvKDt^~]C~~oNC~`~?[GK{~cqgXr~jYCGgOj~~~~~nV*x2LJ~kW~~-SYUY~I~O1~e
+ at S1_69
+GGCGTGCCGGCGGTGCGGCAACGCTGTTCTACCCGATGTGGCATCTGGAAGTGGAAAGCCTGCTGGTGTTGAAAAACAACCGTGGTGTGGAAGGCAACCGCGTGCGCCATATGGACTACGGGGTACAGATCAACAAACTGATGTATACCCGCCTGCTGAAAGGTGAAGATATCACCCTGTTCAGCCCGTCCGACGTACCGGGGCTGTACGACGCATTCTTCGCCGATCAGGAAGAGTTTGAACGCCTGTATACCAAATATGAGAAAGACTACAGCATCCCAAGCAGCGTGTGAAAGCCGTTGAGCTGTTCTCGCTGATGATGCAGGAACGTGCGTCTACCGGTCGTATCTATATTCAGAACGTTGACCACTGCAATACCCATAGCCCGTTTGATCCGGCCATCGCGCCAGTGCGTCAGTCTAACCTGTGCCTGGAGATAGCCCTGCCGACCAAACCGCTGAACGACGTCAACGACGAGAACGGTGAAATCGCGCTGTGTACGCTG
++
+vO:;3VN;VD~Fb^:yFJO,G^Z.wO[ZKV`ElVN~@[gl\Ow=@/6CLUEf0]k~~AGGU6I;Ks4ZDV@~8n=2xDGHV[sZ7LG0K\J'PQ<~9~GKEDKK;FO1Wp:~B`H6|];FKD2~iAW~~~6ABAJ:TW?~O4wOR~UN]NQmOUP-S:]OkhN72r~HP{D_$~~R{B`GMC>~uL~MU][LA;B-bAJ$<KLtGI<~H|0k~~fQKP&_~J<>D;~2KHdEP@>UWHU_'HT~GH>OV>@SF8OXDMKKR?_4MY[h,%Ra5lKM~VZSRynsaGA/QZ>gV~V3U)VG*si8_~D[T~~mUiMGw\8;IE~'~TgDU:HGa>=>;NVM<TEO9cT-NK>UMsELMlMe]jnM,/ZzA(I:UKXM>~OJ5J]SDa_NU>CEa:PP=xK;}QEA~[\pG{$LF^(WN`8fZ8lK~G~x~42xFIpCfCq;>qVBEGVPiM-OUrXT~DO~5CSKJLK>_E5Yx]}~2B<V^>7-5MW/Nj~TkC_A^<<=>BSi~
+ at S1_70
+TGCACCCGGATGCGCAGACAGAGGTGATCCACTTCGGTGACGTCCAGGCGGCGTTGATATTTGATAAAACACTGCCCGTTAACAGCTCGTCCGGTATGAGTGACAGTGGCACAGATCAGTATGGGCATTGAATGTGGAGAACCGGGTGGTGTAAAGCCGTGTTATCACGAACGACTATAACCACCGCGAGGCCCAGAACATACTGATGTCCGTACCGGCGGACATGACCCTGGAGAAGGTTACGACACCAGTTA
++
+7FH&>:FAMM'9XB5?+E?H$&88 at 5EEB<;V0E=3-2J=*9M?e.*A8.OM/31F>;VBN9@@*)H15-DL=):f1^@'-<PIDA&E?Z8;7;=R=5B4QK,QN%P at fd.BZ':B/;MEPEB3-.C-RI98A=4=>C@$BEBA4?G:=AB9K4-XPH*J)[/D<QD<?4`1=-6FC at B-15%?>-=;:*G<';.~87_O+YA?*;5Ed;8DE93Gi2D:6<LLM>L1JJA;HE[9-GA,1<I:J?.JGKE'H@
+ at S1_71
+GGGTGTTTCAAAAACCAATCTGCTGTATTACTTTCCGTCAAAAGAGGCGCTGTATATGCCGTGCTGCGGCAGATTCTCGATATCTGGCTGGCACCAGTTAAAAGCGTTTCGTGAAGATTTCGCTCCGCTGGCGGCGATAAAAGAGTACATCCGTCTGAAGCTGGAAGTCTCCCGCGATATCCGCAGGCTTCGCGCCTGTTCT
++
+TCLP`~~CQD'D=X~GlQ>GY><c at 2ET~>B at O]`@KKA~_B~XW~$N>~iS9^G4PHY<T~IfH:.dD)Ma~KJW587(bYTWIX]y,53F`>:71yVG~27}?@CE4I/m0X>;Dye-^U5Nd~EmT~?@~/r~D;A5RD~FYp?ZO'K at UAK7?`~PZvaIZWE[eDc1E_7~EEHi/f1Y/ON~~<OWeB(MV0:JG}
+ at S1_72
+CGCTGGCAAATCACCTGGGGGCTGGTGCTGAGCATGAGCGCTTTACCTCCAACCAGATGTTCTTCGATCTGGCTCAGGCAAGTGCTTCCGGAGGGCTGAACAACCATAAGATTTACACCACCGGGCGCATCCGTCATATGACATCACCAATCTGGCGGCCTTCCTGCAATCCAGTATGACATTAATGATATTTTTACCGTTAGCGGTGGCGTACGCTATCAGTATACTGAGAACAGGGTAGATGATTCATCGACTAACACGCAGCAACAGAAGATTGCTGCCGGGAAGGCGATATCTGCCGACGCCATTCCTGGTGGTTCGGTAGATTACGATAACTTTCTGTTCCAATGCTGGTCTGCTGATGCACATCACCGAGCGTCAGCAGGCATGGTTCAATTTTTCCCAGGGGGTGGCATTGCCGGATCCGGGGAAATATTATGGTCGCGGCATCTATGGTGCAGCAGTGAACGGCCATCCTTTCCCTGACAAAGAGCGTGAACGTCAGCGACAGTAAGCTGGAAGGCGTGAAAGTCGATTCTTATGAACTGGGCTGGCGCTTTTACCGGTGACAACTGCGGACTCAAATCGCGGCATATTACTCACTTTCCAATAAGAGCGTGGAAAGGAATAAAGATCTGACCATCAGTGTGAAGGACGACAGG
++
+5I:?A=@?4=?8<LCS[8YF4\L?G%9%U?@>?LPW)7H7^>SG,<Pj]IZ-EcSDg at D35fEFIJQ+8@HCPA0608C([?BRLI<%,74G4,54M=Fr06B[IgA06j3AMH9 at GG@J3fH<>SV/D@@I~:Y~G<0PI98>8V2TAaWGYC:GKCM6:C5:Q-:>O?D@$/28h:@O7ILAC%,4U2M1I:?QLKDB-*8 at 3>J0JA78AdKbe0BQ9E:9TL+E?F>SwG8Bv9f~+58C1_A@)9FISW]$F<Z<\9B87MM6=K5?W at 9=LLO/<=N2FJC3~?S9%;C7>F at .9jCBNOTQTf[3JII8J3N'[EH\7B1e+[)K7ZD;%=/5J%K<&=E*VI,/E*>PDUMd/0H<%3H'VM6D.95/GN2ROF:<HI.2B4AGI,9IF7(@fGg?U3CR9~p>F8KD81(M;BJ;E^l12=]AbXU2>KewK:=HD>3OD5U5JDCEQRKb4GNATGGEI[Z=4Gj+qASCI'(JZD7K=^pCXM;+J\o<R7'yR=?2RFIAGJ0BEKCYiBNTF*98;7]BAbRG:6N-ONY=O=5;**E%EH6A)A*=(k4T\qQD4EHbIVI?6S+97GH1FSFHHI<&fBUVAI?|E>_57^F@/~)<GJADT)2A'ATu:J5/Jb.E;&NW:JI>JKLGL41Z6HLF at DEL6NS7K9
+ at S1_73
+GCTTCAACACCCACGTTCGCCAGACCTGCCGGGCAAGCTGATAAATATCCGCCAATACTTATCCCATGCTGAATGAAAGCTGCACTTGCTTTAGCGTCTACTGCCATAAACGCCTCGCGAACCTCCACCCCACTTCGAACGCGCGTGGACCAATTGCCGGCCCTAACCAGCGGATATTTTCCGGATTATCACAAAACAGGAAACCGTCTCTTCCAGCACGCCTGCGCACAGTCCACGCCAGCCAGCATGAGCGGCGGCGACTTCGTTCCCACTCGATTGCAAAACAGCACAGGG
++
+bg%HT9Su[M7S0kQ@@~;L)=H?L~[q4 at Gna3~G?@~x\3=NWL]oIT-JNJGXF-PK~U(`ZZgtzcPFSKg>nAeBRjI- at _[DO~L>Q=Y>oM5O~FkQaH`FFQEtH\~F;FGHBQSe]@$TKh4IoX~F_IZ3~~[-JF5SZ<~Y\AMJ><]V]P^T;Y}VcE[LEHN^]D(7M[cq~~C89%MS@=;ISf^G8Je:O~U~CU/M'RF~OGcH2A~E;gK^F:4<CU/dUXLU~O2~b8WC>9GB5(DAj^~spd2pI8Y\N6D<F4;5~P59Y<8`=K$_9\G^>9
+ at S1_74
+TGGATCAGATCGCGGAACTGTTGCGTATTCTTGGTAGCGCCGATCGTTTGAGGAAGTGATCGTGAAGAGCTGGAGCTGGTCGTGAACAGTTCGGTGACAAACGTCGTACTGAAATCACCGCCAACACCAGACATTAACCTGGAAGATCTGATCACTCAGGAAGGATGTGGTAGTGACGCTCTCTCACCAGGGCTACGTTAAGTATCAGCCGCTTTCTAATACGAAGCGCAGCGTCGGGCGGGAAAGGTAAATCTGCCGCACGTATTAAAGAAGAAGACTTTATCGACCGACTCTGGTGGCGAACACTCACGACCATATTCTGTGCTTCTCCAGCCGTGGTCGCGTCTATTCGATGAAAGTTTATCAGTTGCCGGAAGCCACTCGTGGCGCGCGCGGTCGTCCGATCGTCAACCTGCTGCCGCTGGAGCAGGACGAACGTATCACTGCGATC
++
+b\~/lW67(8~]O7>shV.f?~+@>.MWd,PS_NVDiK9kS1BbuMYK5K at -JBBF+M[hO>6~I]A at p62K;F>cQT?W'<Y9:YN<7<]F4hCNAAK8G?C at S>_5e~LP7iYBNo;EaUHkKX-IVMA~[Q|~_YcAE~cKb;J~`D~OwH0.*h;G%J/J~~4IFpXYQ:g'D~~bA~Bq1/|4o4;TO?~:<4QPZxw>/^?3ZxkXUjPYs;MMAW1Lk1E*poBRbtaQV\V~U=X>)qow-/5CZ;LP~cBfGAGm9jIMQ_M9zi0X\XR_[X_HPyUM[oBb7WV~M_K]MVl5LW`oB+UZI1/z~HHIAGp3\Nbs~>UJh<@~f\md^<M7A@`~Vk/S>|HW99P31k>s)KpQl^FSWPJparQ4^DIX~MC3VPpIH3CI at o|3E~H~NOQ~Icb74:b,FbiZD\1Yc0.^~[f~XuV9I:5dXTw_^INc;EL
+ at S1_75
+TATTGTTCAACGCAGTTCCAAGCATCGCCATTCGTTCGCCCGCTGATGTTTGCGCGTTGGGTAAAATCGCGATGGCTGAGGCACTCGCCATTGCCAGCAGTTGCCGCCACGGTTGTAGCAGTCGCGCCCGCAACCAGATAATAGTGAACACCAGTAAAAGTGCCATAAATACCGCCATTACCCGTGGACCAGTCCACTGTCTCGATGCGCATTTCCGTGGTGCGGTCAAAACCAGTACCAGCTGATCTAAGCCCGGCAACAAACTGGCTGACATCCGCTGACACCGTTTCTCGGTTTTTGTGCACGCTCAGCGCCAGGGATCAGTTCATACGCCAGTAATCTTGTAAACCCTGTAATTGCGCCAGTTGTCCTGTCTCGTTCTGCTGCTCGAGTCAACTCGCGCGCTAAATGCCGTTTGTTCCACTCTTTAATTAAGGGCTTGTCTTTCTCGCTTAATGGCACTGCCGCCAACAGACGGTAACTTTGCATGCGCAGCGA
++
+576<GH.471<5 at C96'6'E;NCE3+3,05O:B0(:$1F473@%()7*66FK3:A:>L?G1=4KB47?9,\E8=F7=/:U=1EEB:357P*<956/=AD'G at H.3==EF%D42<+eX82332DC>-I/D?.;4RA;</530'>:>?7;Z at B2P:&:=J>6;AFD@;3-?<8I>U2,>@?=23J,FF>4A->-I7H9H-<:?L61I<67-RN7.B9a<$0.-G5R./5&3K;NEF*=37N86ID<;19)1>.479/<=<;I6UB.ACA\-?898/%Q57P>R,H5=(G.<6UM1>&R6?P;33$?:O;H2960;-=',50>A+;U?:H%,E95*9$:5;2>M=D8B3:E?>72BH-34%46BEBG/@19/;$&+D9D(I<>:JJ-BW9X`A6B8+9>DB$K.%N0D4$D/:4A3+C%*0L%G2B14,J%IEL(FC3;)00/>;FL?=G?BC@<R7F2<>358+4-F<AF at M%38G,%4V@'?5;>@1J,J*:0-B7R3*
+ at S1_76
+GGCGGCACGGACGGCGGAGCGGTGCATTTAACCGGCACCGGCTGCCCACGGTGGTGATGGGGCCAGCGACGCGCCACGGACATTGTGCGGCATCGATTGGCCGATGCCGCGACATTTTGCAGATGCAGCAACTTTTATCTGCCCTTATTCAACGTCTTACCCGTGAGACGGTTGTTTCAACTGACGGATTTCAGATGATCTCCTGATTAACCCGGAACGGTTATGTTAACGATTCAATTTCTCGTCCTTTGCCTAACGGTCTGCATGCTCGTCCGGCGTGGGAACTTAAAGAACAGTGCAG
++
+9781M@<K'-&6S<61;/@79,4;=,A8C7e,E83?*I;(R<6M&C-<RGR5L.K81;IaMI'B0564-F3&4 at Q55&L4EE=?W:(0NH,H?+:H6D*9=7:L$6.54*@,J.AD at CN=;(6..H&:?,P-98(9F.F-27/)=KI.=EA+D)3IH15:40<D@<07BT9$6=$J8I)$=D+2H5(A=5,L<>=,.C<LAPG%<HFV?KX,=&8637%EC,A4C09IXPD>K><6665&21.I.;19O1/>4GO$(4I'/<=%*,6::>;CIA<V,A6(J<@+7<+:EL9M9'N:*3a=N
+ at S1_77
+TTCTGCAATCTCAAAAGTTAACATCACCAAATATAGAGCATTCAAACACAATGTTCAATAGATTTTACTCTAACCAGTGTGCTATTTTTTAGCAGACTTATACATGGACGAATACTCAAACTGCGATAATAAACTGAAAATATCGAATAAGAATTGATTTTATGAGAATCATCATTATAGCCTATACCATGTAGCATTAACACTTTACACCAAATAGACATACATATACTATTGATTATCGACCTAGGGTAAGTTTATCAATTATGTACGATAGAATCTAAATAATCTATAGTAGCAAGAGGCTTAGGGGGAGATAATGGAGTGGAAGAAAAGCTTAGA
++
+I/,KK=>,A/=>3GR)>~Adb?HE8<DIHC2:HFrI^L-MR at Ak'9=MHSK\FJR4r=ShVl8SDFTR:\ZAK=?KnOPb`SUWBI)R~7O6D%'@`V760BIQ5?UCDHARA:Jbb+N::XB4YCFSL4>SI(H4 at AJ<.01[?3TK6axURB%*<G7>0G6Nn4:Oxh- at -6<T=CD_ADOG<1I%MW?5RGcP0FE/DHDH5VR[>=S46cO[,P\2~;<R8HaL6TR.AK,~EW[9E- at P>E'Q<`:<FlB4dOY3G)G?MJ?:DIX.-I7Q68GXDXEAU>{Q1W;M\Z1IEY9 at DCDm3/OLL>FGGB+QT?F<97*D0DD'?1A;H=9PA?B
+ at S1_78
+ATGCCATCATTCTTGCGTAGCCGGACTAAAACGTTTAGGTCTGAGTCCCGCATTCGCGCCGCGTTACCACCCGAGATTTCTCTTCCGGCGGTAGGACAAGGTGCAGTCGGTATTGAATGCCGCCTTGATGATACGCGCACTCGCGAGCTGCTTGCCGCGCTGAATCACCACGAAACTGCACTGCGCGTTACCGCAGAACGCGCCATGAATACCCGTCTCGAAGGTGGATGTAGGGCCAATTGGTAGCTACGCCGAGCTTATTGATGGTGAAATCTGGCTCGTGCGCTGGTCGGCGCGCCGGACGGTTCGCAGA
++
+~fu~.~nVH5~~[d~_ks~CFl<XN~1gJ|]@F~~~~UNuX&`wP+.~_~~i?{pU^]kY5z_Jw[~Dt6i}6zY2{Dm8yIY~~~~~S=U:~yOG~9RH~j~{J~~~~Qwd]~~Lth~vnK|8~~Lp~Mh[}W)t~~O~~~N~o~~K_~~~~f~yF~~tBg~nm~Jja\U~~S~XIhSm_4R~U~xK|bnmzT at N~-g_H~5D~~M~QbP^QQ^U~~czO~N~(;~~=XG~~K~q~7gEffU}fw~ecJCa~>U~~~y~K~~~~~n~u~~>6~liag~~a~+X{U~p~wX=N1~GsH~P~R;~~q1`~~~Q[
+ at S1_79
+AACTCCGGTTCCAGCACCGCCATTTGCAAAATATCGTTGCGCTTTTCTCGCCGCCGGAAAAACCAACGTTTACCGAACGGGTTAATAAATCTTCCGGCATCTTCAGGAGAGCGATTTTCTCTTCCATCAAATCCTGAAAATCAAAGCGGTCGAGCGTTCCGGCCGCGATAGCTGCGCACTGCATTAAGTGCCGTTTGCAGGAAAAACTGGTTACTGACGCCTGGAATCTCCACCGGATACTGGAAGGCCATAAAGATGCCTTCGCCTGCACGATCTTCCGGCGACAGTGCAAGCAAATCTTTGCCTTTGAACTCAACCGTGCCGCCCGTCACTTCATAATCTTCGCGCCCGGCAAGCGTTGCCGATAAGGTACTTTTGCCGAACCGTTTGGCCCCATAATGGCTGAACTTCGCCGGGCGAACGGCGAGGCTTAATCCACGCAGGATAGCTTTATCTTCCACGCTGACGTGTAAATCTTTAATACTTAACATGTTTATTCCTTATCCGACGCTGTGTTCAAGACTGATGGCGAGGAGTTTTTGTGCTTCAACGGCAAATTCCAGCGGCAGTTCGAGAACACGTCTTTGAGAAACCGTTAACAATCATCGAGATGGCGTCTTCTTCGCTGATCCCGCGTTGCAGGCAGTAAAACAGTTGATCTTCACCAATACGTGATGTCGTTGCCTCGTGCTCCAGTTGTGCGCTGTTATTGCGACATTCGACATACGGGAAGGTATGCGCCCCACAATAGCGCCAATCAGCATTGAGTCGCACTAGTGAAATTGCGCCATTGGTTGCCGTCGGCATGATTTTCACTAAGCCGCGATAACTGTTCTGACTATGTCCGGCAGAGATCCCTTTCGAGATAATGGTCGATTTGTGTTTTTACCGATGTGGATCATCTTGGTGCCGGTATCCGCTTGCTGATGACCGCTGGTCAGCGCCACTGAGTAAACTCAC
++
+f~~I~T~ymS~|~E~~KcXA~~~_ok]c~`VP5SH~jFb~H+h~~Nd<v~I^q~~~G~[CW_BBwQ~~\=jU>~B~Mm~qV~~vpUm~JypQ6zYe~~H~2xT~vGuqeb~jHzF~~zK~@k>EK_[~FgsHDw~j~`@P~~~~Qtb~7]~F~~R~'oaF3*U~x~aMPUK~~yk9T~~X<~b~pbWq~~gohjf~Zy>n}.Ejd`ZgCW~~~~b]J~~~MMfz}~n.G`[rNQAwuNCihycV_vbmZ~Qj?fJm~hZ>zcz~ylg8~qm~&~/_]c~}Z~~LJ~iC_~~72_~e~Hi_i3Gi~Iy~p\q{7Y~NOD>]~-`~_;K<~yQfe\~~i^~=iSjmoFj~RpE~]Ww~E~q~e~Z}J~|yNphf~~~I~V~F~~7N~|~~g>t~~~^~k~QiKh~~S~~H&pT~G=~~~X~~^Ee.~s~[b~~qVoYlVOzVn}~|~hzT~KR~;}~~;X~gDq~_G~}a~[}c~qCn~l~`g~ZlV~K[GIq,~_L~>~2~~~Jm;4@~ozW~g`D~~9 at FNc~}~~XzhZud4~~~p~lGi~~~~rU~wG~~opVIbr~~~bF~~C\l~~c~g~~fi~eG~D~e|,sB^`~Vr~~Z~Evg~~Qf~~~Si~I`2y~gzOo3^Z@~~~;~~f~~WPM~~~~c~~~sud=:wa~~j~lin]RVrQ&~dMf^~W~a5`(y~~gSSD3~5ZR]fSx8Sx~fsJ~ddavgra~bSIcUTR~<[~b~8;u>~Xl=SHVfn~~~=tZA~l\~~~~B~UzkBUr~\Evr4~:\o~TvI\~~~~}a~XVPp~~z~APE~t~*il\:<t|O~J~s~[*UxWg~~~b~~a~~-qtj~~[~[~~<~~zgF{~m~~kj~~T]EGLFhovGj~~u~~|en[~d~Q~UO;~~~~@~~5~Nr`Z~GKhx~J~SUqf5~P?~8vi~b\|G_dZ~~b~~qA^VSSWj~lYtk_Jo(y]O~~[JSc~=~j~OrJTt`Y~~
+ at S1_80
+ATCTGCAGTAAAGTAAGTTTCCCGATGCATCCGTAGCTCAGCTGGATAGAGTACCGGCTACGAACCGAGCGGTCGGAGGTTCGAATCCTCCCGGATGCACCATATTCTCCGTAATCTTCAGCGATGAAGGTATCGAAGAGGTGGCGGTACTAACCGCAAGCACCAGGGAGGATAACGTGCTTTAGCAACGGCCCGAAGGGCGAGCCGCAAGGCGAGTAATCCTCCCGGATGCACCATCTCTTACTTGATATGGCTTTAGTAGCGGTATCAATATCAGCAGTAAATAATTTTCCCGATGCATCCGTAGCTCAGCTGGATAGAGTACTCGGCTACGAACCGAGCGGTCGGAGGTTCGAATCCTCCCGGATGCACCATATTCTCCGAAATCTTCAGCAATGAAGGTATCGAAGAGGTAGCGGAATTAACCGCAGGCACCAGGGATGATAACGTTGCTTTAGCAACGGCCCGAAGGGCGAGCCGCAAGGCGAGTAATCCTCCCGGATGCACCATCTCTTACTTGATATGGCTTTAGTAGCGATATCAATATCAG
++
+~jI~~AaBfgQ~Ns[`~~QzgvlnER~~~w~n~~:|~fn9~~~~GKW~~WaY}~wp~[Ux~~My~-Z_gycLaT=mNGV6b}FBKm{D~~~uo~TF~]j~+~~b~~~~D~~XS~`aa~W9m~z at k~O'V~~Vb~gKw~Ck~~~*i~N|~g~[V^bp=vp[EX`Y~xg]v[~K~}~fzGGStwq~'~Q>`~Mj~]~~~VM``9o]jUs~`~~~\lcGkyN~dJNXj,~j=?|f~R~MiM~|~~e7^~~zl~\~>n8q[~~L~mwgnQy~aZhBK~~Xr~~EnAwub{~k_~~~HYbfY~ViKmrCSUM~~~~d~\8~~~i~`~}m:D~]~7~|qP~sU~OJc~r~:v~vNR]rN7~R~~^y~)Z8~~wTs~a4m~~]`~~r~[K~I~~=~E~ME~QE|~I:fo~~Zy]~aE at LQ2~^~xd[~~W~~k~MH~RtRA_o~k:~v~~v~n~oM~|~~~qbgDs_~~~~~HGOyMF:~~epYQ~UOp~~lZ?~d{J~U~~~~~Jh~;Y~~~X~~NK~mHv~f~t|HmeaRSH>~X[~Gx[~MbvK`~~~~km~~I
+ at S1_81
+GTTGTGTTGCTGATACTCGCCGAACCGGTACCGTATCGCCGTGTTACCGCATTCTGGAACCCGTGGGAAGATCCCTTTGGCAGCGGCTATCAGTTACGCAATCGCTGATGGCGTTTGGTCGCGGCGAACTTTGGGGACAAGGTTTAGGTAACTCGGTACAAAAACTGGAGTATCTGCCGGAAGCGCACACTGACTTTATTTTCGCCATTATCGGCGAAGAACTGGGGTATGTCGGTGTGGTGCTGGCATTTTATGTATTCTTCGTCGCTTTTCGCGCGATGTCGATTGGCGCAAAGCGTTAGAAATTGACCACCGTTTTTCCGGTTTTCTCGCCTGTTCTATTGGCATCTGGTTTAGCTTCCAGGCGCTGGTTAACGTAGGCGCGGCGGCGGGGATGTTACCGACCAAAGGTCTGACATTGCCGCTGATCAGTTACGGTGGTTCGAGCTTACTGATTATGTCGACACCATCATGATGCTGTTGCGTATTGATTATGAAACGCGTCTGGAGAAAGGCAGGCGTTTGTACGAGGTTCACGATGAGTGGTCAAGGAAAGCGATAATGGTGATGGCAGGCGGAACCGGTGGACATGTATTCCCAGGACTGGCGGTTGCG
++
+T%=I8<L^GLRLUTN5F>SO*9%HiA1EMZI]9=]T'HNH=FK5OPM=3[/ECA5S\<>IE']RLS~NANLQJN<@E?0K;79RKQHe/=d'MVTAKTECa9:G%o?E>CG).66P~5-AD>B98JL9U8O1V?NWMBOA~MC-_+6:8:MPJE*87/W at LrEFMIPA0\\BHOE\S/5,N96O48$ML72?6K<_KBMR>}:=N49`:Q~(?6QFQ2<V>A9]CdTE?E>1E~CID/F3\a5<B=[:TF16>N/ZK;QA64G/C at O>EKEAIN10@(N9e8S<=:F>F>U1[Q8?7=QP@=F*@LD7/HB*W;>EGlbC=P$8_8%3i3`>UDPIFIVKH=NC%1?eA=S3BSN?@0E>9T0AL8/;8;xX&ML'60<%A23a;9KM>8B~-aAQ4]@O7 at IF2>GLT:,:P7F.U947VIF;`>@/IX87;XRQGOV@*^,43IH=9P^0PC?L7T4WL?-%:Z37I%I*`L7 at LUPkvL-OEBBOJI}>?,NK<9\l9]>6HGI=QO;PSMZ>F>C8>B|O\MR7~,EH<]4jW3I&_<2N?(Bx?n70R78L;?;IBT9Q/P0<c1<WQBo6CR581OLa~f%I=;;4B^<FLA9$_FWM?6a9$BU18]@
+ at S1_82
+CACGCCGTTTCTGTTTACCAAGGAAATTGATTCTTCCAGCCCGTACCTTTACAAGGCCGTGACCACCGGGCAGACCCTGAAGTCTGCTGAGTTTAAGTGGTACAAAATCAATGATGCCGGTCAGGAGGTGGAGGATTTCAATACGAAGCTTGAGAACGTGAAGGTGGTGAAGGTTAACCCGGCATGCACGACATCAAGAATCCCGCTTACGAGAAGCATAACCACCTTGAGCAGGTGGAACTGCGCTACGAGAAAATCACCTGGACTTACAAGGACGGCAACATCATTCATTCCACGCATGGAGTGAGCGTACCACCGCGTAATTCTGCCGGACGGACAGGGCATCCTGTCCGTCATTTTTATTTTTTCTTCAGCATCTGTTGGCGGGTGCTGAAGAAAGAATTCTCAATCCTGAACACAGACCTGATGCGCCTGGGTTACGGCGAAGGCGGTAGCGTGCTGACGGTCTCCTGACAGTGAGTGAATAACATGGAAAATTCGGCAGCCCTGTTACGTCGTCTTAATCATTACTGTGCCCGTGCACTGGAAGGCGCAGCCTCCCTTTGCCAGACCCGGCCCATGCGGAAATCACCCGGAGCACTGGTTACTGAAACTGCTGGAGCAGGGGGAAGGAGA
++
+D3?DOI^H(I7=FE<6A=[[_2Z?/9OUY%=@CN;:N79P6BCQ?3}UWY/Q>=5UG;)BI>9D1EQ80@><[VB;>AC8KG>@;_:87;MX)=?D8EN><0*7<WD*K>:><'3HdPWDAfNBI3$Z+/G>F%f8XT;E6b:EiAD\7?@JK5C=KWG/<6TZFQ2AoQ=5MI-K at Ge'=M**:E?<P=@/[G=ANB9M:H9=G=*?d=@;-SK=>@JCPAGJ?cB3PN8?LCOJ53-BCUPGJT;?9<Z)PU,D2E*_J:<>1A?<GBR0KcL=0>N>K~PSTU>wO?9@)G3D)ET$?~0-:5@?ED2GX_ at L12*Y[;I;93RI,$IB~1[I<K?7FESABG4d-F5<ZTH3=A3 at AR8Qc2PG54SOL~7DbNB'=JL8V=N61[p`,6-=LVkY(Q$N27:-y0AJP4]IC%V~94_<?~)AV$KY2Kv:9H>8M4^D=546E>5REAB:SD-JDO\JA8<LV(;F6F/EOH.J=:B8/<Y^TlGLMUND-+Gb at ZXIB<EGhIHI:.8>N1:G.8J5-OLC4IRGEKG>'2<<1b<?>F11+O-C$/K at VN;'?/w;2F)3->U6I5k>0.W5W;*7?MIGUbHG?H]DE;*IJZUJ at 4+Z9:@BFB)xEKG?pF>>EH9/a;MhEbH<
+ at S1_83
+GCAATAACATCATCGCTTCTTGTGCATCTACCCCAAAGATTGATGAAATCATTGCACGTAGTCCTACATGGGATAAACATCTGGTTTAAGCTTCCATAGGATTTTATCAAGAGGATATTTACATAAAATTCAGAACCATCTCTTAATACAGAAGTAGCCCAGCAAATGTTTTTACCGACGACGTTATTGAGTTCCGAGCCACTAAATTTGAAACTCAACATCAATCAACTGCCAAAACATCCTCTCTATTTAAGTTTTTGGGCTTCGCTTTCAGGTTGCTCTCGTTATGTTTTACTGCTATAGCTTTGTATCGAAGTCCGCCTTCAGGA
++
+1MG9QP;)0W0,?D.6>U1;-EN.Dda4:^&NIG&RMK67E<:;6MCFFIX%DH.,`>8E;G<;7<A;&ID\<36DXL/Q=tQYjZ;8:ERa31GMA+>SL[M)?;FH%'@L=Fd<S9FA2>NIV=>J?OC/&FC at 7,*7AT:Q?G0G5)*=PQ~HBMIXC3<C.S:;8=ZKDDC:0lW<>9%2?=0Z.PO`:/Q>:-(DO_7:A+F`>QGN+G8B;=>?BBJObBB7ZWNJQ;;GMWY/IBU,- at DNP92H.4N)I8GDA=EG%U6-+.5,F>1%S&Nh:8F>@<O?]=c>+Uo?KDCNt(R\?b^Fg(EFHB;*3 at R,P/Q5d0GHI
+ at S1_84
+ACCATGCTGGGTACTGGTTTAGCAGGTATTGTTTATATCGCTGCGACTCAGGTGCTTTCCGGTATGTATCCGTCTTCTGTAATGGCGGCTTCCGGTGCTCCGTTTGCAATCAGGCTTCAACTATCCTCGGTAACTGGGCTGCGCCGCTGGTTTCTGCATTCACCGCCTTTGCGTGCCTGACTTCTCTGGGCTCCTGGATGATGTTGGTAGGCCAGGCAGGGTACGTGCCGCTAACGACGGTAACTTCCCGAAAGTTATGGTGAGTCGACAGCAACGGTATTCCGAAAAAAGGTCTGCTGCTGGCTGCAGTGAAAATGACTGCCCTGATGATCCTCATCACTCTGATGAACTCTGCCGGTGGTAAAGCATCTGACCGTTCGGTGACTGACCGGTATCCAGTACTGTACTATGCTGCCGTACTTCTACTCTTCGTTGACCTGATTCGTTTTGAAGGCGTTAACATCCCAACTTTGTCAGCCTGATC
++
+~eS~I~~^S~~~~~^ff~tha~~|],|]vM~\xN~oCy~Emi~XN~~y~I~~{~b5oALMVFX}YN2N~~YJP~eavQ~N]kJ5<q~ud+ph~~~~~~MegUs|~:~o:f~b~|Q~3~cfu~~kx{kTbghzl?Df~~~~OmH~PGnR~~gqlN~~x`N~x{hKkr`NZN~Y~~8~~r~~[O=~L~~~D~b~P~~jh@~rVu~~e~iMXP|bb~;rewLoLr at _T~~~~\CF~~~M~_I~s~~~Z~^~bYDr~M~I~a{\~~gilHf~Wtm{OielWsWg~L~qGrj~~KOk~e.(]g~y~YY9rmpyGwF5~~u~Z~pA<~tm~`Y\xA~hM~YnayNlWA[~9~~Iu^Re~u~~)?6b~r~~e~dvxvJ~~U~m~_f_l~~Q?r~?d~iJXL9l~hJr~@Wt\~~DR^hm~Y~~{d~~~44RO?m~o~jQn~~~bk~b~U~h\h_-~~~w~~w~~L~Cw]ZM~~~EdvmB~hqQ~~.dd}~_
+ at S1_85
+AACAGAGCTGCGACCACCACCACACACAGGTTCAGATCGCGCCAGCGCCCGGTGCATACTTTCATGATGCAGTACGACATAAAGCCGAGTGCAATCCCTTCGGTGATCGAGAAAGTAAAGGGCATCATCACCGTGGTAATAAACGCAGGCACCGATTCGGTAAAATCATCCCAGTTAACGCGCGCCAGGCTCGAAGTCATCAGCACGCCAACAAAGATTAACGCTCCGGCGGTTGCGTAAGGAGGAACCATCCCACCACGGTGAGAAGAACATAACTAACAGGAACATAACGCCAACCACAACCGCAGTCAGCCCCGTGCGACACCGACTGCCACACCAGAAGTACTTTCAAATAGGAGTA
++
+=Q'.]iQQC<<D0O5JLc%6d^XHP74N<iU&OW/JS9SKFC7KHOL<+LE>yO{0{CXIBLJG`1:/>AQfb>{EBKZ[OPHNEG7ZB.Ed3FZ.K35-h<([+>RZ,+QSU at _N>2IU852NO(TRE>YC,9O0IF&LH4DS`RFIdECDN{:V>0J^U[P\4D>QA?C@]>9U54CBM='SK;)+OKoHe/X0I9^.IPD^C1O*;HD><E6%78 at y;NeGUSLB-za.OR%:c1<G/7<PPY2=0E<O;H>CA@=Y@:oDA<RNSB<^K&LSZ63>OT2 at SV_HI9C+[TFK4N@<F1GH2;@(Wf?H2Z)h/<FMa at 25:.YP5<BNA->FN4mGB>8GHH^L;VA7;dO]>I*F<
+ at S1_86
+AGCATCACGAATTTCCGGGTATTCTTCCGGCCAGAAGGTGGTATGCAGGCGGTTGGTATTGAAAGCACCACCACGCGATGCCCCTGCTCACGCAGTTTATGCATGATGGCGATCACTTCCGGGCGCAGCGCAACAAACACCGCCTGCCAGCCGTGAGAGAACTGCTCGTAGCTTAGCGGTAGAGCCATCTCATGACACAGCGCCTCTGCGAACGCTTCGTCGCTAATTTCCCCACGCTCAGCTGATGAAACGCCTCCCCCATATGAAAACTCTTCTAAGCGATGCCAGCGGAATACGCGTTAAATCGCTCCAGGCTCCCAGCACACGGTTAAAGTCGATATCGACAATCACATTACCTAAATCAAAGATATAGGCATTTTTGCCTCCTTTCGCGCCACAAGAAATTAACTGTAGCGGGAAAGGATGGGTTTGGCTATGTGGCAATAAGGGTAATCTTGTGATGCTGATTGCGAAAAAGCAGAGTAATTTCACT
++
+inJ~U<oho~S~}~~pGUbQ;Z~I{~A]~R~X~?~~~C at S~ZHeK~0=~c=~~~~Nfpn7~S[]A~L~~6.~]~~Xt~][bO~~~s~dJgT~hrAqR6\~=]icVgi{e~~x~{s~Tk4b~WISy'~~6JxCWGXps~Q9d~~Uz<~~q{~D~2\^2~4~~{~J~.~`r~P2h~>~~~uY^ibBWnSAhU~\~ajjb~|~h~~~pzdl]:ujZ4_tpvg~|KL_qe{~QDoh~I,Z~ew~jSQsUt~u'dd|t`~MvU~v_VDIc~g~[C~uF~O_YM~Av~m*J^~~b~_~~U~_J~KV~~~~q~F{:~~e~We2cNp~~~a~~F~~@J~~~~{J~~~o{\~Za.FuOfe>Nx~~~~fu<dZxA~~s~uJO~~X~~Nm~z~~wv|_Kq~~bV~:I~~~_R~]~tz|Z~P5W~3~_~?Z;~~f~~WD]~v~~WB|~lF~J[~dAt~SY~pH|c_b~|XX]~6VP~~~d~z^~fr9>iWJhwW~<e\~FcXT\D
+ at S1_87
+CAATATCGAAGACGTGCCGGATGTCGTTTTTGCGGAAAAAATCGTTGGTGATGGTATTGCTATCAAACCAACGGGTAACAAAATGGTCGCGCCAGTAGACGGCACCATTGGTAAAATCTTTGAAACCAACCACGCATTCTCTATCGAATCTGATAGCGGCGTTGAACTGTTCGTCCACTTCGGTATCGACACCGTTGAACTGAAAGGCGAAGGCTTCAAGCGTATTGCTGAAGAAGGTCAGCGCGTGAAAGTGGCGATACTGTCATTGAATTTGATCTGCCGCTACTGGAAGAGAAAGCCAAGTCTACCCTGACTCCGGTTGTTATCTCCAACATGGACGAAATCAAAGAACTGACAAACTGCCGGTAGCGTAACCGTG
++
+OrlqErE^kQNCL?TmWKMyj[SqUROZHM_TGT=Z=O7+`E)zPUb:, at cT~G<AW[X]qH+@~?Vp]^V<.W5S at TK~Q?S=CMKW:3G*MH~:UT(+EW|3~_H~Ef~m_?.)[>HR~^DLhCEJT/;WJf\IQdFmU~K.?=dWI;=IUNRJNTR1G][aP7pbx~V?~bBo~bO0}J;PtK~5)N;H|Sm:[^}DHBPE`d<\RIN>eX^J3HOgTH=@YbIFO+XqCtw-IeMZxYp\DEi5[-y%Jh at 2TV8fGOIHI*8dhT<LA/:B4\3O_]O:A^~R1cG:CNPIOXs-~1Ny7G<|0~JO[{Y~HDO:4TD4cgMBL2+I9 at D~E>s4=DUU~~QEBaM3/ariS15_9l8~f;~j3S{BU at SQ=iS
+ at S1_88
+TGCCTGGCTGGTTCGCCAGCACTTGCTGATGTCGGTGACAGCACAACGCCGCGATATTCAGGACCCGAAGTCATCAAGCAGTTTGCCGAAGAAGTTCAAACGGAAAATCGTCTGCGCTATCTGGTATGCCTGACAGTGGCTACATTTGCGCCACCAACGAAACGCTGTGGAATAGCTGGAAGCAAAGTCGTTGCGCGAACTCTATTTTGCCACCGAAAAGCAGCTACGACGCGGAATGCAAAACACGCGGATATGCGCGAACGGGTTCGCCATCACCAACTCCAGGCACTGGCACTACGCGCATGGATAACATCGACGAAGAGGCGCTGCACCAAATTGGTCACGCTGTCGTGCTAATATTTGTCCGCCATAGCCCAAATCAAC
++
+IUZy+~4~~cWi^c~~j{VIf~U~F`~qH~,WSZ~4X~)~~XZ?j-<-}[~~ZNxQ^l~jV~pl~9ZQoD9hMIo~J`gu~al~_L~~gx2lQ]~IaJH~U~Qe~~~~L_c|p~W~}Eg~lUe~vV|5Pr~hZ~~Omu~h~QK[~Q;N[kE~~\vN`>Qud~A~~~~V`l~Kl~i8~ZRT~[Fafks~]rf~\ZZA~;^>]~R{sj~k~~ne9zwj~Q]Ass~~~~~s~KdK~e~d~m~oSV~W~b~zb~~-X`~*_l_MgsGY9~l~UUZkYD~1X]e~W~j^^R^lmlh~Fu~L]`~ad8~~~U~Rv~~~~e:DfNv~jEZ`jM\w]<6pD~Y5~~T_~~~pP|{dyW~IMXZfT{C`jH~twTb`~en~OL:b~~wi~ua~
+ at S1_89
+GCGATCCAGTTAACCAGGCGATTGCTGCGCTTAATCGTGCCAAAGAACTTGCCATCTGCCGGACTTAACCGCCGACTGGCCGCCGAATGGCTGGAAACCTTCCAGGCGAAAGAGCTGGAAGCGACTGAAAAAATGCTCTCTCTTGAGCAGAAAATGAGCATGGCGCAAACCGCGCACAGCCAGTTTGAGCAGGCTTATCAGCTGGTGGTGGCAATCAACGGCCCGCTGCGCGTAACGAGGCGTGGATGTCGCTCGCGAACTATTGCGCGAAGGGGTCGATCAG
++
+s~~yj~X~jy]b>~;~[D`NX~_~~~8XcCL/*~{W~~M~`YLfC'CODi`MO~~~d~F~~>z~~Y>[~3AQ[TfPTobI~~C7q~w0~~zw~YbeaT~RV~fuG~tLT1BAtN~MIl~~VaN~i_C~x~G~~^B{=~uZhhaA|X8su~J{NGm}jwq~Xhv~v~V~M~~{^~~~9~Nzr\ZogwR~7reZ~>JSod~kCiMSf~~jW3~~^TOt~Q]~r~2cyMe~`KjUy}WDKF`e~DCW]Y|1l5~Du~Y8~n4~~lF\~NR~Aa_.jh at x~~zAp^~
+ at S1_90
+TGGCAACGCAATGACCAGTTTGCGCCCATGCTTCATTTGCAGCGCGACAACCACAGCTTAAATCCGCCCGGCGGTTTCGACTGGGCAGCAGGTTCAAGTGTATTCATCTTTGCTCCTTAAACGTCAGCACCACACAGCTGTCCACTTCCCAGCACAAACGCACTTCGTCGCCCCAGGTCGGTAACCCTTACGATGACGATGGGCGTTTTGTAGCTGGGCGCTAATCATCTGCCCACTTTTCAGACGAACGTGATACACCGAAAGATCGCCGAGATAGGCAATGTGTATCACCTCCCCCACCGCGAAGTTACAACCATTGGCGGGCGGCTCTTCGCAAAGCATGATTTTTTCCGGGCGCAGCGCTACGTGTACCGGCACGTTATCGACACTGAAGCATCCGCATCGACTTTCAGTGGATGCACCAGCCCCGGCGAATCAAGCACCAGGCCATCTTCCTGACGCTCTTTGAGT
++
+~~XK>su~>~ZQi~O~Q|~~5gMw~~3^lC~Z~~U~Zym`Tx`lnrhm6Mf=zxgeFjtysT~P~~FXPd~g?@~`dS~gcJY?q~X~<}Gz~~y~d~Oy~|~:m~P~~~QZ?YLyCT\K~gsyFS[[~m~~~~rlkrVbjVkqrg&fjF`Q^~yU~~sqX\FWPhrk>~~pH~~jS~~~~H~N~`f~J;;ea~~`PC~V~`v~LZ^b/DKuS~~JA6vR~ff;a~R`>~f4@?}TL:{~~tqMX^D_Mk`:~~CJ~Dnz2)}C~]G~N~~~a[?gh~w{S3~PysIS~g~jg]_Dij~f@}]T~P~V~^~NLdas~Z~W~j~8~~IGe~sYW~p@~X\~dX>ujgOYq~t]YKa~EZA[~|yQ`P@[WcP~jVE~lYCB~gfQbwLl~U~{~W{EV~dp~y?R~M~RV~CMH[Mo~]@g`~~D,rQ=D{w~Bh~pey~jY|~e'~+~'~~`]~WIUjP_~u~~C~_ZV~~
+ at S1_91
+AATTTCATTTTTGAATTTGGAGTCCGGGTCTGATGTATATCTATTTCCTGACCAGACCAAACTGGCGCTAAGAATTCTCACGAAAAAAGGATTAATCCTAAAGATTAGGTGAAATAACACAAAAGTTTCTGTAAGTGAGAACTTGAGGTTTTTTATTAACACATCAGGACGCAAGTTGATATCATGAAAAGATAACATTCAATTTTTACAATGGATTGCGGTGATATTCTCTGTTAAATTTATGAATAAAAATTATGCGGCAAATAAATTGCCGCAACATATTATACCAACAGAAACATACCAAAAACTCAACAACAAATATTCCCGAGCATAAATCAACCCGGGAGTTACTATTCTGAAGCGAGAAATTTGTCGAGATAAGGTACAACAAAGGAACAGAAGTCTGGAATATACCATT
++
+ZAEH58JQLKB>O=@C5?@=26FH):UAKNCI=9*4FP/+37 at BICJ*2:*UDJ352/M'?>8?PUI.K=3 at 6J2,m?D2TH.A,O:7 at 4M,HFB0CVK$S)+3:K7:9>,6JG;QBJF1)AJ87['=QM=K<A)K;PF6U8AG,?048QXR>HH8FIL/CMe,Y@<O<01:&6C-KKOD4LA5A9BM0`%98$<7*;1),P<.1B4&^CE3>K>B2C=Q.&I=?GIB0>D5:B:-50.GL9eM2%=TC>LI>BI)9,D*A98?~G0I<7?51(.:)/7ECD&0KJ3ETQI)I--6:6*K,.B61524;)<*G$4+8<JHP,8DG`]CH at iO3AE:OS/Ka.P4CCL~BC6?5CE%B2C:6CJ>H>;1V,%<4;1R+(;42FH=9$m>FC;%K3'A4=IE at 7/8GMH9;2AB<OA7:A
+ at S1_92
+CCGGTGCTGACGCGCTGGAGTTAGGTATCCCCTTCCCGACCCACTGGCGGATGGCCCGACGATTCAAAACGCCACTCTGCGCGCTTTTGCGGCAGGTGTGACTCCGGCACAATGTTTTGAAATGCTGGCACTGATTCGCCAGAAACACCCGACCATTCCCATTGGCCTGTTGATGTATGCCAATCTGGTGTTTAACAAAGGCATTGATGAGTTTTAGCCCAGTGCGAAAAAGTCGGCGTCGATTCGGTGCTGGTTGCCGATGTGCCAGTTGAAGAGTCCGCGC
++
+ETRVB'O_BMTGPUJANUGOIEL&@>@=>OF\bN0OOXKGHD5O>7EB,38+L:-C'UW>GAIZENI;HK[G7@>`I^?,@}B2H]IINW(LJJG6 at GW?;0&DEMRFIE~,EBED?E52 at EV.8R;&@4PM;QG6D at PDuOeYGCOy,dBUW<a/28AFN8I??GG](>Q=CNG/G>@(;^X49RHN?@J3(JE@:CK;9B'OFH64qI6I]@3D91:IF;4hj,M8G@\U8:eSZC=7C\V@=>;fCFi at 71M5EBPCZ)KB;HJEC%O%:qPm=-_6%8u
+ at S1_93
+TAACAAAGTTTTTCAGCTCGTTCTATAAACGGGCCAGACTCATTTTTTCGCCGGGATTGTTAGGATCATCAATCTGAATCACCGAATGGGTTGGGCTTTAGTCTTCCCACTGGCAACTTCCTTTTGTGCGATATCGTTTAAAGGATACTGCACAGGGTACTTGGGTTGATGACATACAAGCATTACCCGTCGGCAAGTCGCATCACCTCTTCGCGATTAAACGCCCATTTGTCTTTACCCACTTCAAAACGGCTGACGGTAATCACCTGCGGTGCAGCCAGCGCCGCGCAAACTGGTGAGTAACAGAAACGCCAGAATACTTTTTTTCATCATTTTCGTAATCCATCAAAAAGGTTCGAGATCGCAAGCAGGCTGATATCACCAGCACTACCGCACCTATCGCCCATTCGAGTTAGTCATCCACTCAAACCAGGGTGCCGCACGATCTTCATCCTGCCTCATGCGCGGTACAAGAACATAACGATTAGCCAGCGCAATGACCACCATAATCATCACCAGGATGGCTTTGAGCAATAAGAGTTGGCCCCAGTAAGTCGTAAGCGTGGGGGGAAATCCGGTAATCAACAATGCATTAAGCACGCCGCTTGCCAGTACGCCGATCACCGCAAAATGCCCGCACCAGGAAAAAC
++
+F5KQT6'MYHpdRA%DU>+>X~U?AJ4>EG~XMJw. at W?s~5IR27SI+ETZ*=wBE]MW2M~ATt&Q@@:@-QO6H3?7JgeK^JJaksIW2IqH~U{@R1=TE\KJcGP<r,EUL_H(GNX9T at PCk:PI?]\A8kHw=sf3{8J4TNh~~M2B]ERBMeYI at 4HG}_BkFd{BW-2?Qtq?3YNO~ac;R;COAXpu5m_LXHKCJ>?~h5ruaHJMk=FJGVyE~O?2GZP$bX~<n?kZ+^TOf\~XUDbZWI%Ut~I~FV~6B[%9VSQX%i;fQ8<m:~QO/QgY=>WQQUGg%GYW{>C|*LLBCV8:CYXFxM~hIFG~Y]MY18C\-CFdLd/LJuUJB~Lu:;]QO2<:OWfCag~PfFDAj3[~~&H~[Qnj\S4zHB1ovT:H7lw~u}t_%T\[E2Y$VPR,fX~<x_-QExW;aA4Y<~I<C4oDrPD?an~S@{_9HOIJJ'S;~YQ:GXEGMyY1K[CyR~NNU?G~]^IlM~_KFCTJXVa6QJ<[5<UH:3ma'>LLXjDhP`Al_R~Is_?KqIh~CK0K?Ww~iGI>=J)KqB~VQ~^K]~ST.ICFQFNM~IJPMQ]HYLeQLdo~aT8=P[cSfcu0kHPPNX.~vNDBXgf4UZ14A=COUc18SZ<IbK}A2[t[ry~Q^NVE;I
+ at S1_94
+AAAAGAAACCGTCAGGGTGGTTGTTTTCCCTTTTGCCACCGTCACCGGATGTAGGCGTCACCTTAATCGCACTGACCGGCGTAATTTTGCTGCGTCTTCCGCTACACAAGGTTTACCCACGTTAGTGACTTTCACCGTGCGGGTGATCACTTCTTTCGCCGTCACGGCCTTACCGATACGCTGACCCAGCCACGAAACACATCCACCGTGCCATTCGGAAAACGGATTTTATAGGCCCGGACATCGCCGCTTTCAAACCAGCCTATAAGCCCTTTCTGGCCTTCCTCTCCCGGTTTCCAGGCCAGCGTAAAACTGGTATCACCTGCAGATTTCTGCCCCTGCCCGGTCGCGGTCCAGTCCGCGTCTTCATCATGCAGGTAGTTATCATCGTAGGATTCTGCCTCATCTGCCCGG
++
+G~H?9mOgT]MaTNH=ITb?HKN}:LRER^'wHHl@~2bRO@*f^7]kKNceWBKbK\g~:hUP}LMq at A:MNs~{$]a:zQ~QPHE~ely~ZPME[Y=Xv07H~6(YQbfL*_~Qj*=Wo6SAFaS*JNZEQOJ=E9lmWYDXI'x@`5SV{:UAV;C,GY0urM4>E~c~EeU\g at XRE@u~5N?]H>M^oPG`\:Z+gL~8ADicP>FS:~PAK_Zf~9AQYU~5`Z7S75[46 at oWL|=DoLRDu~ik444M[4S;N[]EO8IU3B~@woQb*fe|aWNSKSa7HE~m^K;~RSBGR~DLfk~iH``k4 at JPP;Gv>GMXcXT/~SJ=O\H*BESWc,No~UIOMM8IhU+U at FYrVc37>LmMaKhQM'7LF at Yf\dyPIYjF\??E~):=M~Y~9>=E>EaQQK0~~~
+ at S1_95
+CAGCCAGGCATTGCGCTTTCAGCGCCTCGCGCAGGGCAATCGCTTCACGAGCGTAGCCGACAATACGCGGAGAATCGAAGTTAACGTTGGTCAGGTTGGAGAAAAGGCACGTGGCGCGAAGCTGTCAACATCGTGTTGATGATGCCGTATTCACGCGCTTTACCGCCCAGGCAGAAAGCCCTTGCAGCGCCGCGATGAGTAAATCCTGAAGGTCAGAAGTTTCGCCGTTTTACCACACATCCCCTGCGCGTATGGCAGCCGTTTCCTGCCGGAGTACGGATAGTTTGTTCACATTGCACACAAAACATGATCACACCTTTTAAAGTTATATTTAATATACATGTTTAAGGTTAAGACGCTTAACGCGGGGAT
++
+O>N}A at K2F_X's5:^H`*=4UL>S~>^~GHNCSJQeRFmC~Tt3_V<>XGC~POQM\~;c0Y1WdEKFY$FXT at LESUP~[Qv>+:IL8R~=}]gK.~NJ~g0Ba?D.hQ~?2UKhMP~Ee{OKG*nI\0QHpUWGgYIG>5S~[]gq~d=`KI=c9avjh:|J`CaC~pF9~{8HGYAE;K1Dj~f[LKPBT;ZEK:EH+I?])14H^0JU?Mya;]LU:[T^lBbCJfH;=Tp>HZDg_\K~tFKbbqHWS~GJ~jJ2Gc at R4iMMObC@=Kx3MFk@~~nOU~WQN.FlQC6G6ThV1iS~AN.KQUZMAA[l=-6Zf;@GLG\RX@;Kd_I`~:==NSH^i1D^5JIVCG~^JHC0F;N8VTTR_cM
+ at S1_96
+CGCTGTTTTTCTACCTGATCACCACGGCTACCACACGCCCCACAATTTCATGACCCGGTACGCAGGGGTAAACCGTCCCCGCCCACTCGGAACGGACCTGGTGGAGATCGGAATGGCAGACGCCACAGTAAGCGATTTCGATTTTGACATCATTCGGTCCCGGTTCACGCCGTGTGATATCCATCGGTTCAAGTGGTTGTTTAGCGGAATATGCCCAATAGCTTTGTCTTCATTGTGTTTACTCCTGATTAGCTATGTGTATTTGGCGATGCCTGATATGTCATCCGCAAAACGCGTCCATTGAATATAGCCAATATTTAAACCACCCGATCCAGCCCCAACATGCCGCGAACCTGAATGAAACAGAGCAGCAACGTTCCCCATAAGGCCATCGTCAGGTAGGGGCTATACCGAGAATTTGA
++
+MYO~~KgP|s~~V;C]~h{~xW^~~~_oR~@N?=H~+_~}~ze2~Z_[q9IQEW~~~1ON~V_xFWrF|Wrx~3{c\~~~~~~~~ov~q~~I~;~~\I|0cTd]<~~M~Z~\+~E~\kg~FI~~N`~nmQ[~hn~Yc{iG~^g~~]Y<~o~~g^~{~Y~@mC~0x~D=Ht~}~Pe}qmkRA:Q[b~'~@~~vxabV~kF1~@~xX~CyRv~C{Dd~~Ps~~`\`qn{f<~h~x~^~zTr~~S~YGO~~bmkK~xoXMQ~1~+~N~~~`IV</k~Dy5;cQ^~`Ar~J~~~pV~YgOP_^Gyd~K84~~~1>R~RBZ~T~|~c~MkN`jq~wQ~oK-r~~d~~e~~m;|p~GVF~fw9vHu_~u]Z~I~n'~Yh\~c~z~Q\+VgwkC}HR>k~gy~4qpp\g{~~U8h~~hU~~~[Uu~`v~
+ at S1_97
+GACGACGCCAGGTTTTCCAGTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTCGGTGAAAGAACTGAGGCGGTGTTTTTTATTGGAAATCAAAAGGCTATTTTAGGTAATTAACAGAGTTTTTCAGCTCGTTCTATAAACGGTGCCAGACTCATTTTTTCGCCGGGATTGTTAGGATCATCAATCTGAATCACCGAAATGGGTTGGCTTTAGTCTTCCCACTGGCAACTTCCTTTTGTGCGATATCGTTTAAGGATACTGCACGAGGGTACTGGGTTGATGACATACAAAGCATTACCCGGTCGGCAAGTCAGCATCACCTCTTCGCGATTAAACGCCCATTTGTCTTTACCCACTTCAAACGGCTGACGGTAATCACTGCGGTGCAGCCAGCGCCGCTGCAGAACTGGTGA
++
+^y~vMCBlQ[e~~~~R~~bdEDA^~\~~[LN~~~C,~NY3l~s9fkVUMghXrqeX~_~2p1iK~s~no8\~~~~UQMXbd~h1]~C;Z~?z~\tR~Z~i^~H~u8P~(kSd@~Rd{EV~~\On~q~b~[~VR~Q~xOexi~~qOB~~~<a~a_\~~~?~S~~T]G~~EZat~U~~H~xF~9~~c~~_~~1~T~~u~b_~k~CX~;>~~~xs~[]~~QEz~~M~u~reI~Kcl8~HC~z~VXT4au~[uy~[o~AKe|_^bZ~~^Xwf~XGI^_~n~~~_Hci~Jrv_5,~Q[Z~hu\~hb~wpRrE~?~~OOd~]~k~~XU~brn~N|tfBeBze}nR~nL~l`v~N~a~~{vaSK>Qu||~~~G\Q|]~~mhk~~M{~rf~S@~U26hwhJE^~1i~g~efK~~~~~l_W~~mv~rc~=~~~~\h~~`Ohvexn~VG~qj~[eX~
+ at S1_98
+AAAGATTGCGTCATTCGCGTCGCTTGTGATGTCACCAATCCGCGGTGGGCGATAACGGCGCATCGCGCATCTTTGGCCCACAAAAGGGAGCCAGTGAAGCGATGATTGTTGAGCTGGACAATAACCTCTCTCACTATGCCGATGTCATTAAAAAAGCCGCATGTTGATGTGAAAGATGTCCCCGGCGCAGGAGCTGCGGGCGGTATGGGTGCGGCGCTGATGGCGTTTCTTGGTGCGGAACTGAAAAGTGGTATGAAATCGTCACTACGGCGCTGAATCTGGAGGAACTATTCACGATTGTACGCTGGTGATCACCGGTGAAGGGCTATTGACAGCCAGAGTATTCACGGCAAGGTACCGATTGGCGTGCAAACGTGGCGAAGAGTACCATAAACCGGTGA
++
+~\~~yq{~I8V.~S~XFRM~Sp~~B~?a[bDI~~~aRo~JsTKli~t_E~~]GrU~\[aflV_V~VeMuPEOfVk~~E~9}~ar]drio~~?9EG~L]~~p;~~D:m8~OAa~i~F~\_TED[J~SI~sA~KHT~3 at W>3hJcRcb\Gm~`yv~~u~~o[r;jjYTlKmsN~lu4~~J@\{g~W~]}~?R9dWZ~^qSm~vj}J~i~~y~~BPs_M~;{~=~2G6~V`~rVKB~B~Q~g~~?~IeEDM~~~+h~GXlMf>~~R~gZv~X~\-~XJKNU[G~C~@~~_M*v5~]Ua~^~X{{y|_~uZ~zz~gm~[NohJoDNDfek=~A^U~-~~~DRbm{R*N~EK?sZb~jkJ~~~[~^^cJ~[{~[@j~CW~v`~~~RD~k`w5~v^y~k=~_L]\kQ
+ at S1_99
+CCTCTGCCTGAGTAGTTCAAATCCTGCTCGACCATACTTCTGGCGTTTCAGCATCTTCTTCAGGCAGATTTACATGACCTTCGACAACACCATTACTCCAGCGACATGATTGCCTCACTATAGCTGCAGCATCAGCTTCCATCCCCGCCGCCCACGCGCCGAAATTCTGCTGAACCGCTTCGTGGACTCGAGTGAACCAACTGCTTAGCTGTGATTTATTTTGGGTTTTAGAATACGGTAGAACTCGAGTGCCAGTTGCTGCGCTATTTTCAGCTCAGGTTCTTTTTCACACATCAGACTAATAAATCGGGAAGCATAATTTTCTTCATCCCTGGTTATTCTCAGGGCATCAACCAGCGGCTTACCCGGGAGACTGAAGGAAGTCTGACGGCAGTAGTATACCGGTGGGTTCCAGCCTTACGCCATTTGGCAACCGCACCCTGACGATGGGTTTCATGCCTGTAAATCCCCGGGCCACCATTTCCCGCCATATCCGGCTGGCGTTATAATTACCACTTTCTCGTTGCTCTTTTAACCACTCCCTCCATGGTGTCAGCGAAAAACGAAACCGCTGTTGAATCCCTGGAAAGCTGGTTGCGGAAAAGATGAAGACCCAGTCGC
++
+dW5?KK at J9;&:,'<C&&>NF:\,K=D\S24;/?=>N(7G~MC,Q-5U.67ND6a>I0=39FC(H-?0D:RDH at 7DE@.8N<3)5F+(P at IIJYL,AR56K1`A6J5g9;8G:+8C7;33>??8=9<+J39B;N3FD'3 at Y+L8D1>%A5G-I6]60TOk0H/,0989;+S9053M_G9,>.37TF-,0>B86HY=/6K*:5Y*?1U><KB^Z96OBS>I<.BGP at F@:*BI8A::6L<GCAFB=&'BV)::2?CBC:0)<897<G3GAD>5I3:6GYQ3&K-GPH8?D(ABP==84E+9:,.EL)cA?:8?G<JCGD1;F7 at BJ)=@6+UD1 at O(BN00I>4?=(144:1]F6-(8ABB2+J:CEY7,B~PCGZ/7/R@?+?I90L36b9=)E:FTO@&>*;1K:M/*HEB9HT5U6&G5:38B/*?'.+ at 2>5(;BE>R;B61+*C9,QB%C[BJ?EL2HT;JEa48D4H-:*J=CaMHO=6?\<8'/E4</1590%EM5$=1AJD4I??1?LF>JA)YJ6:Y=1802@&d@%1DKMS.R<8<J@=BD?,>L&]L2J%:P?Q^*+C;<@@P?;9O$L>2P-E5.1-8%B4;ED:H5?2G-HB11>)EN+RH2.'ML/EL
+ at S1_100
+TGCGATGTTGACACGTCTTATCCTTCAATGTCGGATGCGACCTGCCGCGTCTTATCCGACCTACGGTTGGCACGCATCCGGCAATGTTGTAAGGCTACAACCCTAACGCAATTTCAGCGCCTGACGTTTAACACGCCAGCACGCTCTGCCGCCATTAACCCGAGATTACGCACAAAACGCAGCGGCGGCAGATTATTATGAATCCGGCATAAAACAGATCCAACCACTTTGCATAATGA
++
+<5~\Nm at b;l]5Il:SUH\+NFNL?~Pb7f@&w~\IPXrZ?TOV;H<a_UO~~]Ho\UWQJUQEA~KaF*;RFH;N_0~NX=JDvO<E6PTP78i4f~S9$^[F6kQSw@/C9<SaIM4O~I_h?Cx*BN;~>R+,8SU`PH)IBE:IN~sNFF(RW}DrJ<TF_V4m=JEKOFfNH~pmVN/~h1?L~P.7JW;9 at A]9H+Co44GLa~*HK2- at nBIlNLZudk`*f<q<>;a'~i<
TEST lastal -a1 -D1000 /tmp/last-test galGal3-M-32.fa
lastal: quality data not used for non-fastq query versus fastq reference
#
@@ -3061,6 +3465,8 @@ p &+/~~~?:<=8731,
# Query sequences=100
+>Q2LCP8
+MVCLFENLMNMIKYSIYILPLIILIVLSISIKKDVQRVHIIIQSLKLtlivimiviGIEESIYVKLNGHLIKTELIKLFEYLLLGVSYMIIKMFEEGVTEGKKTKITDEGLILIYSSIIGMLISMEAHNLITLFLSLEISSICFYILALNKNSRKGIEGGLKYYIIGGIATTILLLGIVSIYKSTGSLMYTDLLVIVMENTDDYRIQMGIALIVLGLILKLGIAPFHGWLIDVYEGAGMLMTFYLTITQKlvtlmvlinlyqnliiytnaimftngliILILVTLVVGTIGSLRQQKLIRFIAYSAIVNSALLILMLAGSMSEELMVNSVYYLINYIIGLTVLMSLIMGFLRLNDRGTIEDIYQLKNMWVINMFGAIVYILVLMYLAGLPPMTNFISKILILLPYMVLGRVYLTMLAFFLSVGVMIYYMNLVKIIIIDKVQTHEQGVAELEITSKPTKGGRRIVLGVMWLIFSQLYLDEILNVIKVIVALI*
TEST lastal -Q1 -pbadcodon.mat -a17 -b1 -F9,9,9,9 -X1 -D1e3 /tmp/last-test sd-ccs-100.fq
lastal: quality data not used for DNA-versus-protein alignment
#
=====================================
test/last-test.sh
=====================================
@@ -24,6 +24,7 @@ trap 'rm -f $db*' EXIT
{
lastdb $db /dev/null
+ lastdb -D $db
lastal $db /dev/null
# spaced seeds, soft-masking, centroid alignment, matrix file
@@ -32,6 +33,7 @@ trap 'rm -f $db*' EXIT
# multiple volumes & query batches
lastdb -m1 -s1 -C2 -R10 $db $dnaSeq
+ lastdb -D $db
try lastal -fTAB -i1 -w0 -e40 $db $dnaSeq
# match-counting, with multiple query batches
@@ -62,7 +64,7 @@ trap 'rm -f $db*' EXIT
# probabilistic alignment with quality scores
try lastal -Q1 -j6 -e90 -a9 $db $fastq
- # sparse index, generalized affine gap costs
+ # sparse index, generalized affine gap costs, self-alignment
lastdb -w2 -c -R10 $db $dnaSeq
try lastal -r3 -q3 -a21 -c2 -e60 -f0 $db $dnaSeq
@@ -155,6 +157,7 @@ trap 'rm -f $db*' EXIT
# fasta query versus fastq reference
lastdb -Q1 -R10 $db sd-ccs-100.fq
+ lastdb -D $db
try lastal -a1 -D1000 $db galGal3-M-32.fa
# prb query versus fastq reference
@@ -171,6 +174,7 @@ trap 'rm -f $db*' EXIT
try lastal -Q1 -pbadcodon.mat -a17 -b1 -F9,9,9,9 -X1 -D1e3 -j4 $db sd-ccs-100.fq
try lastal -Q1 -pBL62 -b1 -F3,3,3,3 -X1 -j4 -e56 $db sd-ccs-100.fq
lastdb -qcR01 -B1 $db Q2LCP8.fa
+ lastdb -D $db
try lastal -Q1 -pbadcodon.mat -a17 -b1 -F9,9,9,9 -X1 -D1e3 $db sd-ccs-100.fq
# BlastTab format
View it on GitLab: https://salsa.debian.org/med-team/last-align/-/commit/1ff64d32778edf62bb1e1a00b4b1a632554a46d2
--
View it on GitLab: https://salsa.debian.org/med-team/last-align/-/commit/1ff64d32778edf62bb1e1a00b4b1a632554a46d2
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