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<h3 style="margin-top: 20px; margin-bottom: 10px;">

Étienne Mollier pushed to branch upstream at <a href="https://salsa.debian.org/med-team/python-treetime">Debian Med / python-treetime</a>

</h3>

<h4 style="margin-top: 10px; margin-bottom: 10px;">

Commits:

</h4>

<ul>

<li>

<strong style="font-weight: 600;"><a href="https://salsa.debian.org/med-team/python-treetime/-/commit/e6064017dcfbf63072b9d8a06cc5775d5eff2f6e">e6064017</a></strong>

<div>

<span> by Étienne Mollier </span> <i> at 2024-11-09T21:16:32+01:00 </i>

</div>

<pre class="commit-message" style='white-space: pre-wrap; display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: #fbfafd; border-radius: 2px; margin: 0; padding: 8px 12px; border: 1px solid #dcdcde;'>New upstream version 0.11.4</pre>

</li>

</ul>

<h4 style="margin-top: 10px; margin-bottom: 10px;">

12 changed files:

</h4>

<ul>

<li class="file-stats">

<a href="#8ec9a00bfd09b3190ac6b22251dbb1aa95a0579d">

README.md

</a>

</li>

<li class="file-stats">

<a href="#4c23f3e77a0ef00cf8da63e8e50eef5197724f75">

changelog.md

</a>

</li>

<li class="file-stats">

<a href="#2acc65acdda9ae987dbf8da8251ed25fe5a18110">

test.sh

</a>

</li>

<li class="file-stats">

<a href="#3fbbf22b1b6cb7b53b1579b816069457bd8a7eaf">

<span class="new-file">

+

test/test_vcf.py

</span>

</a>

</li>

<li class="file-stats">

<a href="#69dc641dc8a4f2ceee2025d190e2e761dcae3c84">

treetime/CLI_io.py

</a>

</li>

<li class="file-stats">

<a href="#716e6f6c16580800d13452615e2c01668aacc288">

treetime/__init__.py

</a>

</li>

<li class="file-stats">

<a href="#595202a65707f2c13afa5a4958366d4eb8a9353e">

treetime/argument_parser.py

</a>

</li>

<li class="file-stats">

<a href="#b990c4f689cacd4a1e8800b187c4078a5c5ed01f">

treetime/gtr.py

</a>

</li>

<li class="file-stats">

<a href="#a2e471fd9fc09543e8fd92727442680e1b76576b">

treetime/treeanc.py

</a>

</li>

<li class="file-stats">

<a href="#0994bbb65b28bed19201420b96136d5e9f676859">

treetime/treetime.py

</a>

</li>

<li class="file-stats">

<a href="#86f02b8df99e58795d36ed9e703173e372da3411">

treetime/vcf_utils.py

</a>

</li>

<li class="file-stats">

<a href="#884b9238819e29c9c3a7ccd69fd2f6ed9f2fab18">

treetime/wrappers.py

</a>

</li>

</ul>

<h4 style="margin-top: 10px; margin-bottom: 10px;">

Changes:

</h4>

<li id="8ec9a00bfd09b3190ac6b22251dbb1aa95a0579d">

<a href="https://salsa.debian.org/med-team/python-treetime/-/commit/e6064017dcfbf63072b9d8a06cc5775d5eff2f6e#8ec9a00bfd09b3190ac6b22251dbb1aa95a0579d"><strong style="font-weight: 600;">README.md</strong></a>

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1

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<td class="new_line diff-line-num" data-linenumber="1" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

1

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC1" class="line" lang="markdown"><span class="p">[</span><span class="nv" style="color: #008080;">![CI</span><span class="p">](</span><span class="sx" style="color: #dd1144;">https://github.com/neherlab/treetime/actions/workflows/ci.yml/badge.svg?branch=master</span><span class="p">)</span>](https://github.com/neherlab/treetime/actions/workflows/ci.yml)</span>

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<td class="old_line diff-line-num old" data-linenumber="2" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

2

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<td class="new_line diff-line-num old" data-linenumber="2" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC2" class="line" lang="markdown"><span class="p">[</span><span class="nv" style="color: #008080;">![anaconda</span><span class="p">](</span><span class="sx" style="color: #dd1144;">https://anaconda.org/bioconda/treetime/badges/<span class="idiff left right deletion" style="background-color: #fac5cd;">installer/conda</span>.svg</span><span class="p">)</span>](https://anaconda.org/bioconda/treetime)</span>

</pre></td>

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<tr class="line_holder new" style="line-height: 1.6;">

<td class="old_line diff-line-num new" data-linenumber="3" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="2" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

2

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC2" class="line" lang="markdown"><span class="p">[</span><span class="nv" style="color: #008080;">![anaconda</span><span class="p">](</span><span class="sx" style="color: #dd1144;">https://anaconda.org/bioconda/treetime/badges/<span class="idiff left right addition" style="background-color: #c7f0d2;">version</span>.svg</span><span class="p">)</span>](https://anaconda.org/bioconda/treetime)</span>

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<tr class="line_holder" style="line-height: 1.6;">

<td class="old_line diff-line-num" data-linenumber="3" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

3

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<td class="new_line diff-line-num" data-linenumber="3" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

3

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC3" class="line" lang="markdown"><span class="p">[</span><span class="nv" style="color: #008080;">![readthedocs</span><span class="p">](</span><span class="sx" style="color: #dd1144;">https://readthedocs.org/projects/treetime/badge/</span><span class="p">)</span>](https://treetime.readthedocs.io/en/latest/)</span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="4" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

4

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<td class="new_line diff-line-num" data-linenumber="4" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

4

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC4" class="line" lang="markdown"></span>

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<td class="old_line diff-line-num" data-linenumber="5" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

5

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<td class="new_line diff-line-num" data-linenumber="5" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

5

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC5" class="line" lang="markdown"><span class="gu" style="color: #800080; font-weight: 600;">## TreeTime: maximum likelihood dating and ancestral sequence inference</span></span>

</pre></td>

</tr>

</table>

<br>

</li>

<li id="4c23f3e77a0ef00cf8da63e8e50eef5197724f75">

<a href="https://salsa.debian.org/med-team/python-treetime/-/commit/e6064017dcfbf63072b9d8a06cc5775d5eff2f6e#4c23f3e77a0ef00cf8da63e8e50eef5197724f75"><strong style="font-weight: 600;">changelog.md</strong></a>

<hr style="overflow: hidden; border: 1px solid #e1e1e1;">

<table class="code white" style="border-spacing: 0; border-collapse: collapse; width: auto; font-family: monospace; font-size: 90%;" bgcolor="#ffffff" width="100%" cellpadding="0" cellspacing="0">

<tr class="line_holder new" style="line-height: 1.6;">

<td class="old_line diff-line-num new" data-linenumber="1" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="1" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

1

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC1" class="line" lang="markdown"><span class="gh" style="color: #800080; font-weight: 600;"># 0.11.4: Bug fixed</span></span>

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<td class="old_line diff-line-num new" data-linenumber="1" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="2" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

2

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC2" class="line" lang="markdown"><span class="p">-</span> fix output of mutations into the <span class="sb" style="color: #dd1144;">`branch_mutation.txt`</span> file which was masked by a conditional</span>

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<td class="old_line diff-line-num new" data-linenumber="1" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="3" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

3

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC3" class="line" lang="markdown"><span class="p">-</span> adjust CLI help</span>

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<td class="old_line diff-line-num new" data-linenumber="1" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="4" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

4

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC4" class="line" lang="markdown"><span class="p">-</span> adjust output precision</span>

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5

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC5" class="line" lang="markdown"></span>

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<td class="old_line diff-line-num new" data-linenumber="1" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="6" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

6

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC6" class="line" lang="markdown"><span class="gh" style="color: #800080; font-weight: 600;"># 0.11.3: Bug fixed</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="1" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="7" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

7

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC7" class="line" lang="markdown"><span class="p">-</span> calls to some random number generator errorred after the recent switch to treetime owned RNGs.</span>

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<td class="old_line diff-line-num new" data-linenumber="1" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="8" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

8

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC8" class="line" lang="markdown"><span class="p">-</span> default argument for clock-filter method had a spelling mistake</span>

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<td class="old_line diff-line-num new" data-linenumber="1" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="9" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

9

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC9" class="line" lang="markdown"><span class="p">-</span> a branch length optimization function didn't handle profiles==True correctly.</span>

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<td class="old_line diff-line-num new" data-linenumber="1" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="10" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

10

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC10" class="line" lang="markdown"></span>

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<td class="old_line diff-line-num new" data-linenumber="1" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="11" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

11

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC11" class="line" lang="markdown"><span class="gh" style="color: #800080; font-weight: 600;"># 0.11.2: improvements in VCF parsing/writing + clock-filter functionality</span></span>

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<td class="old_line diff-line-num new" data-linenumber="1" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="12" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

12

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC12" class="line" lang="markdown"><span class="p">-</span> rewrite of the vcf reading and writing code including many more tests, closer alignment with spec, and performance improvements by @jameshadfield <span class="p">[</span><span class="nv" style="color: #008080;">PR #263</span><span class="p">](</span><span class="sx" style="color: #dd1144;">https://github.com/neherlab/treetime/pull/263</span><span class="p">)</span></span>

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<td class="old_line diff-line-num new" data-linenumber="1" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="13" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

13

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC13" class="line" lang="markdown"><span class="p">-</span> clock-filter command can now remove detected outliers with the additional flag <span class="sb" style="color: #dd1144;">`--prune-outliers`</span>.</span>

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<td class="old_line diff-line-num new" data-linenumber="1" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="14" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

14

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC14" class="line" lang="markdown"></span>

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<td class="old_line diff-line-num" data-linenumber="1" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

1

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<td class="new_line diff-line-num" data-linenumber="15" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

15

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC15" class="line" lang="markdown"><span class="gh" style="color: #800080; font-weight: 600;"># 0.11.1: bug fixes and tweaks to plotting</span></span>

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<td class="old_line diff-line-num" data-linenumber="2" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

2

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<td class="new_line diff-line-num" data-linenumber="16" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

16

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC16" class="line" lang="markdown"><span class="p">-</span> fix division by zero error during GTR inference</span>

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<td class="old_line diff-line-num" data-linenumber="3" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

3

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<td class="new_line diff-line-num" data-linenumber="17" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

17

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC17" class="line" lang="markdown"><span class="p">-</span> improve doc strings in parse dates</span>

</pre></td>

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<br>

</li>

<li id="2acc65acdda9ae987dbf8da8251ed25fe5a18110">

<a href="https://salsa.debian.org/med-team/python-treetime/-/commit/e6064017dcfbf63072b9d8a06cc5775d5eff2f6e#2acc65acdda9ae987dbf8da8251ed25fe5a18110"><strong style="font-weight: 600;">test.sh</strong></a>

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<td class="diff-line-num unfold js-unfold old_line" data-linenumber="19" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

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<td class="line_content match" style="color: rgba(5,5,6,.24); padding: inherit;" bgcolor="#fbfafd">@@ -19,5 +19,10 @@ if [ "$OUT" != 0 ]; then</td>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC19" class="line" lang="shell"><span class="k" style="font-weight: 600;">  </span><span class="nb" style="color: #0086b3;">exit </span>1</span>

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<td class="old_line diff-line-num" data-linenumber="20" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

20

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<td class="new_line diff-line-num" data-linenumber="20" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

20

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC20" class="line" lang="shell"><span class="k" style="font-weight: 600;">fi</span></span>

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21

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21

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC21" class="line" lang="shell"></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="22" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="22" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

22

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC22" class="line" lang="shell">pytest test_vcf.py</span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="22" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="23" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

23

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC23" class="line" lang="shell"><span class="k" style="font-weight: 600;">if</span> <span class="o" style="font-weight: 600;">[</span> <span class="s2" style="color: #dd1144;">"</span><span class="nv" style="color: #008080;">$OUT</span><span class="s2" style="color: #dd1144;">"</span> <span class="o" style="font-weight: 600;">!=</span> 0 <span class="o" style="font-weight: 600;">]</span><span class="p">;</span> <span class="k" style="font-weight: 600;">then</span></span>

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<td class="old_line diff-line-num new" data-linenumber="22" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="24" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

24

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC24" class="line" lang="shell"><span class="k" style="font-weight: 600;">  </span><span class="nb" style="color: #0086b3;">exit </span>1</span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="22" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="25" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

25

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC25" class="line" lang="shell"><span class="k" style="font-weight: 600;">fi</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="22" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="26" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

26

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC26" class="line" lang="shell"></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="22" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

22

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<td class="new_line diff-line-num" data-linenumber="27" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

27

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC27" class="line" lang="shell"><span class="c" style="color: #999988; font-style: italic;"># Clean up, the 202* is to remove auto-generated output dirs</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="23" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

23

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<td class="new_line diff-line-num" data-linenumber="28" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

28

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC28" class="line" lang="shell"><span class="nb" style="color: #0086b3;">rm</span> <span class="nt" style="color: #000080;">-rf</span> treetime_examples __pycache__ 202<span class="k" style="font-weight: 600;">*</span></span></pre></td>

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<br>

</li>

<li id="3fbbf22b1b6cb7b53b1579b816069457bd8a7eaf">

<a href="https://salsa.debian.org/med-team/python-treetime/-/commit/e6064017dcfbf63072b9d8a06cc5775d5eff2f6e#3fbbf22b1b6cb7b53b1579b816069457bd8a7eaf"><strong style="font-weight: 600;">test/test_vcf.py</strong></a>

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<td class="new_line diff-line-num new" data-linenumber="1" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

1

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC1" class="line" lang="python"><span class="kn" style="font-weight: 600;">import</span> <span class="n" style="color: #333333;">pytest</span></span>

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</td>

<td class="new_line diff-line-num new" data-linenumber="2" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

2

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC2" class="line" lang="python"><span class="kn" style="font-weight: 600;">from</span> <span class="n" style="color: #333333;">textwrap</span> <span class="kn" style="font-weight: 600;">import</span> <span class="n" style="color: #333333;">dedent</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="3" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

3

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC3" class="line" lang="python"><span class="kn" style="font-weight: 600;">from</span> <span class="n" style="color: #333333;">treetime.vcf_utils</span> <span class="kn" style="font-weight: 600;">import</span> <span class="n" style="color: #333333;">read_vcf</span><span class="p">,</span> <span class="n" style="color: #333333;">write_vcf</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="4" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

4

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC4" class="line" lang="python"><span class="kn" style="font-weight: 600;">from</span> <span class="n" style="color: #333333;">treetime</span> <span class="kn" style="font-weight: 600;">import</span> <span class="n" style="color: #333333;">TreeTimeError</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="5" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

5

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC5" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="6" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

6

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC6" class="line" lang="python"><span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">create_vcf</span><span class="p">(</span><span class="nb" style="color: #0086b3;">dir</span><span class="p">,</span> <span class="n" style="color: #333333;">content</span><span class="p">):</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="7" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

7

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC7" class="line" lang="python">    <span class="n" style="color: #333333;">d</span> <span class="o" style="font-weight: 600;">=</span> <span class="nb" style="color: #0086b3;">dir</span> <span class="o" style="font-weight: 600;">/</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">data</span><span class="sh" style="color: #dd1144;">'</span></span>

</pre></td>

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</td>

<td class="new_line diff-line-num new" data-linenumber="8" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

8

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC8" class="line" lang="python">    <span class="n" style="color: #333333;">d</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">mkdir</span><span class="p">()</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="9" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

9

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC9" class="line" lang="python">    <span class="n" style="color: #333333;">fname</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">d</span> <span class="o" style="font-weight: 600;">/</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">no-header.vcf</span><span class="sh" style="color: #dd1144;">"</span></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="10" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

10

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC10" class="line" lang="python">    <span class="k" style="font-weight: 600;">with</span> <span class="nf" style="color: #990000; font-weight: 600;">open</span><span class="p">(</span><span class="n" style="color: #333333;">fname</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">w</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span> <span class="k" style="font-weight: 600;">as</span> <span class="n" style="color: #333333;">fh</span><span class="p">:</span></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="11" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

11

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC11" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">print</span><span class="p">(</span><span class="nf" style="color: #990000; font-weight: 600;">dedent</span><span class="p">(</span><span class="n" style="color: #333333;">content</span><span class="p">),</span> <span class="nb" style="color: #0086b3;">file</span><span class="o" style="font-weight: 600;">=</span><span class="n" style="color: #333333;">fh</span><span class="p">)</span></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="12" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

12

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC12" class="line" lang="python">    <span class="k" style="font-weight: 600;">return</span> <span class="nf" style="color: #990000; font-weight: 600;">str</span><span class="p">(</span><span class="n" style="color: #333333;">fname</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="13" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

13

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC13" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="14" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

14

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC14" class="line" lang="python"><span class="k" style="font-weight: 600;">class</span> <span class="nc" style="color: #445588; font-weight: 600;">TestMalformedVcf</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="15" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

15

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC15" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="16" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

16

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC16" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">test_no_header</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">tmp_path</span><span class="p">):</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="17" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC17" class="line" lang="python">        <span class="k" style="font-weight: 600;">with</span> <span class="n" style="color: #333333;">pytest</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">raises</span><span class="p">(</span><span class="n" style="color: #333333;">TreeTimeError</span><span class="p">):</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="18" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC18" class="line" lang="python">            <span class="nf" style="color: #990000; font-weight: 600;">read_vcf</span><span class="p">(</span><span class="nf" style="color: #990000; font-weight: 600;">create_vcf</span><span class="p">(</span><span class="n" style="color: #333333;">tmp_path</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"""</span><span class="se" style="color: #dd1144;">\</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="19" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

19

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC19" class="line" lang="python"><span class="s" style="color: #dd1144;">                ##fileformat=VCFv4.3</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="20" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC20" class="line" lang="python"><span class="s" style="color: #dd1144;">                1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">5</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">T</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">C</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">GT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span></span>

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<td class="new_line diff-line-num new" data-linenumber="21" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC21" class="line" lang="python"><span class="s" style="color: #dd1144;">            </span><span class="sh" style="color: #dd1144;">"""</span><span class="p">))</span></span>

</pre></td>

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</td>

<td class="new_line diff-line-num new" data-linenumber="22" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

22

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC22" class="line" lang="python"></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="23" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

23

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC23" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">test_meta_info_after_header</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">tmp_path</span><span class="p">):</span></span>

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<td class="new_line diff-line-num new" data-linenumber="24" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC24" class="line" lang="python">        <span class="k" style="font-weight: 600;">with</span> <span class="n" style="color: #333333;">pytest</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">raises</span><span class="p">(</span><span class="n" style="color: #333333;">TreeTimeError</span><span class="p">):</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="25" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

25

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC25" class="line" lang="python">            <span class="nf" style="color: #990000; font-weight: 600;">read_vcf</span><span class="p">(</span><span class="nf" style="color: #990000; font-weight: 600;">create_vcf</span><span class="p">(</span><span class="n" style="color: #333333;">tmp_path</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"""</span><span class="se" style="color: #dd1144;">\</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="26" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC26" class="line" lang="python"><span class="s" style="color: #dd1144;">                #CHROM</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">POS</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">ID</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">REF</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">ALT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">QUAL</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">FILTER</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">INFO</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">FORMAT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">sample_A</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">sample_B</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">sample_C</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="27" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC27" class="line" lang="python"><span class="s" style="color: #dd1144;">                ##fileformat=VCFv4.3</span></span>

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<td class="new_line diff-line-num new" data-linenumber="28" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC28" class="line" lang="python"><span class="s" style="color: #dd1144;">                1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">5</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">T</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">C</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">GT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span></span>

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<td class="new_line diff-line-num new" data-linenumber="29" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC29" class="line" lang="python"><span class="s" style="color: #dd1144;">            </span><span class="sh" style="color: #dd1144;">"""</span><span class="p">))</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC30" class="line" lang="python">    </span>

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<td class="new_line diff-line-num new" data-linenumber="31" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC31" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">test_inconsistent_sample_numbers</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">tmp_path</span><span class="p">):</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC32" class="line" lang="python">        <span class="k" style="font-weight: 600;">with</span> <span class="n" style="color: #333333;">pytest</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">raises</span><span class="p">(</span><span class="n" style="color: #333333;">TreeTimeError</span><span class="p">):</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="33" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC33" class="line" lang="python">            <span class="nf" style="color: #990000; font-weight: 600;">read_vcf</span><span class="p">(</span><span class="nf" style="color: #990000; font-weight: 600;">create_vcf</span><span class="p">(</span><span class="n" style="color: #333333;">tmp_path</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"""</span><span class="se" style="color: #dd1144;">\</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="34" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC34" class="line" lang="python"><span class="s" style="color: #dd1144;">                ##fileformat=VCFv4.3</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="35" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC35" class="line" lang="python"><span class="s" style="color: #dd1144;">                #CHROM</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">POS</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">ID</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">REF</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">ALT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">QUAL</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">FILTER</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">INFO</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">FORMAT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">sample_A</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">sample_B</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">sample_C</span></span>

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<td class="new_line diff-line-num new" data-linenumber="36" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC36" class="line" lang="python"><span class="s" style="color: #dd1144;">                1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">5</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">T</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">C</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">GT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC37" class="line" lang="python"><span class="s" style="color: #dd1144;">                1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">6</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">T</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">C</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">GT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span></span>

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<td class="new_line diff-line-num new" data-linenumber="38" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC38" class="line" lang="python"><span class="s" style="color: #dd1144;">            </span><span class="sh" style="color: #dd1144;">"""</span><span class="p">))</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="39" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC39" class="line" lang="python"></span>

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<td class="new_line diff-line-num new" data-linenumber="40" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC40" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">test_no_data_lines</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">tmp_path</span><span class="p">):</span></span>

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<td class="new_line diff-line-num new" data-linenumber="41" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC41" class="line" lang="python">        <span class="k" style="font-weight: 600;">with</span> <span class="n" style="color: #333333;">pytest</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">raises</span><span class="p">(</span><span class="n" style="color: #333333;">TreeTimeError</span><span class="p">):</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="42" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC42" class="line" lang="python">            <span class="nf" style="color: #990000; font-weight: 600;">read_vcf</span><span class="p">(</span><span class="nf" style="color: #990000; font-weight: 600;">create_vcf</span><span class="p">(</span><span class="n" style="color: #333333;">tmp_path</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"""</span><span class="se" style="color: #dd1144;">\</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="43" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC43" class="line" lang="python"><span class="s" style="color: #dd1144;">                ##fileformat=VCFv4.3</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC44" class="line" lang="python"><span class="s" style="color: #dd1144;">                #CHROM</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">POS</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">ID</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">REF</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">ALT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">QUAL</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">FILTER</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">INFO</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">FORMAT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">sample_A</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">sample_B</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">sample_C</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC45" class="line" lang="python"><span class="s" style="color: #dd1144;">            </span><span class="sh" style="color: #dd1144;">"""</span><span class="p">))</span></span>

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<td class="new_line diff-line-num new" data-linenumber="46" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC46" class="line" lang="python"></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="47" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC47" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">test_consistent_ploidy</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">tmp_path</span><span class="p">):</span></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="48" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC48" class="line" lang="python">        <span class="sh" style="color: #dd1144;">"""</span></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="49" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC49" class="line" lang="python"><span class="s" style="color: #dd1144;">        The spec heavily implies that ALT alleles must be supplied for each copy</span></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="50" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC50" class="line" lang="python"><span class="s" style="color: #dd1144;">        of the chromosome, even for no-calls: </span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">If a call cannot be made for a</span></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="51" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC51" class="line" lang="python"><span class="s" style="color: #dd1144;">        sample at a given locus, </span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;"> must be specified for each missing allele</span></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="52" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC52" class="line" lang="python"><span class="s" style="color: #dd1144;">        in the GT field (for example </span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">./.</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;"> for a diploid genotype and </span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;"> for</span></span>

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<td class="new_line diff-line-num new" data-linenumber="53" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC53" class="line" lang="python"><span class="s" style="color: #dd1144;">        haploid genotype).</span><span class="sh" style="color: #dd1144;">"</span></span>

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<td class="new_line diff-line-num new" data-linenumber="54" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC54" class="line" lang="python"><span class="s" style="color: #dd1144;">        </span><span class="sh" style="color: #dd1144;">"""</span></span>

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<td class="new_line diff-line-num new" data-linenumber="55" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC55" class="line" lang="python">        <span class="k" style="font-weight: 600;">with</span> <span class="n" style="color: #333333;">pytest</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">raises</span><span class="p">(</span><span class="n" style="color: #333333;">TreeTimeError</span><span class="p">):</span></span>

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<td class="new_line diff-line-num new" data-linenumber="56" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC56" class="line" lang="python">            <span class="nf" style="color: #990000; font-weight: 600;">read_vcf</span><span class="p">(</span><span class="nf" style="color: #990000; font-weight: 600;">create_vcf</span><span class="p">(</span><span class="n" style="color: #333333;">tmp_path</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"""</span><span class="se" style="color: #dd1144;">\</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="57" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC57" class="line" lang="python"><span class="s" style="color: #dd1144;">                ##fileformat=VCFv4.3</span></span>

</pre></td>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC58" class="line" lang="python"><span class="s" style="color: #dd1144;">                #CHROM</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">POS</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">ID</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">REF</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">ALT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">QUAL</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">FILTER</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">INFO</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">FORMAT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">sample_A</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">sample_B</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC59" class="line" lang="python"><span class="s" style="color: #dd1144;">                1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">5</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">T</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">C</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">GT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1/1</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC60" class="line" lang="python"><span class="s" style="color: #dd1144;">            </span><span class="sh" style="color: #dd1144;">"""</span><span class="p">))</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC61" class="line" lang="python"></span>

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<td class="new_line diff-line-num new" data-linenumber="62" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC62" class="line" lang="python"><span class="k" style="font-weight: 600;">class</span> <span class="nc" style="color: #445588; font-weight: 600;">TestMultipleChromosomes</span><span class="p">:</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC63" class="line" lang="python">    <span class="sh" style="color: #dd1144;">"""</span></span>

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<td class="new_line diff-line-num new" data-linenumber="64" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC64" class="line" lang="python"><span class="s" style="color: #dd1144;">    These are valid VCFs but TreeTime cannot yet parse them</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC65" class="line" lang="python"><span class="s" style="color: #dd1144;">    </span><span class="sh" style="color: #dd1144;">"""</span></span>

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<td class="new_line diff-line-num new" data-linenumber="66" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC66" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">test_multiple_chromosomes</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">tmp_path</span><span class="p">):</span></span>

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<td class="new_line diff-line-num new" data-linenumber="67" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC67" class="line" lang="python">        <span class="k" style="font-weight: 600;">with</span> <span class="n" style="color: #333333;">pytest</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">raises</span><span class="p">(</span><span class="n" style="color: #333333;">TreeTimeError</span><span class="p">):</span></span>

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<td class="new_line diff-line-num new" data-linenumber="68" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC68" class="line" lang="python">            <span class="nf" style="color: #990000; font-weight: 600;">read_vcf</span><span class="p">(</span><span class="nf" style="color: #990000; font-weight: 600;">create_vcf</span><span class="p">(</span><span class="n" style="color: #333333;">tmp_path</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"""</span><span class="se" style="color: #dd1144;">\</span></span>

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<td class="new_line diff-line-num new" data-linenumber="69" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC69" class="line" lang="python"><span class="s" style="color: #dd1144;">                ##fileformat=VCFv4.3</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC70" class="line" lang="python"><span class="s" style="color: #dd1144;">                #CHROM</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">POS</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">ID</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">REF</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">ALT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">QUAL</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">FILTER</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">INFO</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">FORMAT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">sample_A</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">sample_B</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">sample_C</span></span>

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<td class="new_line diff-line-num new" data-linenumber="71" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC71" class="line" lang="python"><span class="s" style="color: #dd1144;">                1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">5</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">T</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">C</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">GT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span></span>

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<td class="new_line diff-line-num new" data-linenumber="72" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC72" class="line" lang="python"><span class="s" style="color: #dd1144;">                2</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">6</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">T</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">C</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">GT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span></span>

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<td class="new_line diff-line-num new" data-linenumber="73" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC73" class="line" lang="python"><span class="s" style="color: #dd1144;">            </span><span class="sh" style="color: #dd1144;">"""</span><span class="p">))</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="74" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC74" class="line" lang="python"></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="75" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

75

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC75" class="line" lang="python"><span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">zero_based</span><span class="p">(</span><span class="n" style="color: #333333;">idx</span><span class="p">):</span></span>

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<td class="new_line diff-line-num new" data-linenumber="76" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC76" class="line" lang="python">    <span class="sh" style="color: #dd1144;">"""</span><span class="s" style="color: #dd1144;">Useful as a form of code commentary. Convert idx from 1-based to 0-based</span><span class="sh" style="color: #dd1144;">"""</span></span>

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<td class="new_line diff-line-num new" data-linenumber="77" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC77" class="line" lang="python">    <span class="k" style="font-weight: 600;">return</span> <span class="n" style="color: #333333;">idx</span><span class="o" style="font-weight: 600;">-</span><span class="mi" style="color: #009999;">1</span></span>

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<td class="new_line diff-line-num new" data-linenumber="78" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC78" class="line" lang="python"></span>

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<td class="new_line diff-line-num new" data-linenumber="79" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC79" class="line" lang="python"><span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">write_data</span><span class="p">(</span><span class="n" style="color: #333333;">tmp_path_factory</span><span class="p">,</span> <span class="n" style="color: #333333;">sample_names</span><span class="p">,</span> <span class="n" style="color: #333333;">data_lines</span><span class="p">,</span> <span class="n" style="color: #333333;">reference_seq</span><span class="p">,</span> <span class="n" style="color: #333333;">meta_lines</span><span class="o" style="font-weight: 600;">=</span><span class="bp" style="color: #999999;">None</span><span class="p">,</span> <span class="n" style="color: #333333;">reference_name</span><span class="o" style="font-weight: 600;">=</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">reference_name</span><span class="sh" style="color: #dd1144;">'</span><span class="p">):</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="80" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC80" class="line" lang="python">    <span class="sh" style="color: #dd1144;">"""</span><span class="s" style="color: #dd1144;">helper function to create and write a VCF and FASTA file. Returns a tuple of filenames</span><span class="sh" style="color: #dd1144;">"""</span></span>

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<td class="new_line diff-line-num new" data-linenumber="81" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC81" class="line" lang="python">    <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">meta_lines</span><span class="p">:</span></span>

</pre></td>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC82" class="line" lang="python">        <span class="n" style="color: #333333;">vcf</span> <span class="o" style="font-weight: 600;">=</span> <span class="sh" style="color: #dd1144;">"</span><span class="se" style="color: #dd1144;">\n</span><span class="sh" style="color: #dd1144;">"</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">join</span><span class="p">(</span><span class="n" style="color: #333333;">meta_lines</span><span class="p">)</span><span class="o" style="font-weight: 600;">+</span><span class="sh" style="color: #dd1144;">"</span><span class="se" style="color: #dd1144;">\n</span><span class="sh" style="color: #dd1144;">"</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="83" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

83

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC83" class="line" lang="python">    <span class="k" style="font-weight: 600;">else</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="84" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

84

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC84" class="line" lang="python">        <span class="n" style="color: #333333;">vcf</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">dedent</span><span class="p">(</span><span class="sh" style="color: #dd1144;">"""</span><span class="se" style="color: #dd1144;">\</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="85" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

85

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC85" class="line" lang="python"><span class="s" style="color: #dd1144;">            ##fileformat=VCFv4.3</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="86" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

86

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC86" class="line" lang="python"><span class="s" style="color: #dd1144;">            ##contig=<ID=1,length=50></span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="87" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

87

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC87" class="line" lang="python"><span class="s" style="color: #dd1144;">            ##FORMAT=<ID=GT,Number=1,Type=String,Description=</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">Genotype</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">></span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="88" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

88

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC88" class="line" lang="python"><span class="s" style="color: #dd1144;">        </span><span class="sh" style="color: #dd1144;">"""</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="89" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

89

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC89" class="line" lang="python">    <span class="n" style="color: #333333;">vcf</span> <span class="o" style="font-weight: 600;">+=</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">#CHROM</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">POS</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">ID</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">REF</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">ALT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">QUAL</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">FILTER</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">INFO</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">FORMAT</span><span class="se" style="color: #dd1144;">\t</span><span class="sh" style="color: #dd1144;">"</span> <span class="o" style="font-weight: 600;">+</span> <span class="sh" style="color: #dd1144;">"</span><span class="se" style="color: #dd1144;">\t</span><span class="sh" style="color: #dd1144;">"</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">join</span><span class="p">(</span><span class="n" style="color: #333333;">sample_names</span><span class="p">)</span> <span class="o" style="font-weight: 600;">+</span> <span class="sh" style="color: #dd1144;">"</span><span class="se" style="color: #dd1144;">\n</span><span class="sh" style="color: #dd1144;">"</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="90" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

90

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC90" class="line" lang="python">    <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">line</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">data_lines</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="91" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

91

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC91" class="line" lang="python">        <span class="n" style="color: #333333;">vcf</span> <span class="o" style="font-weight: 600;">+=</span> <span class="sh" style="color: #dd1144;">"</span><span class="se" style="color: #dd1144;">\t</span><span class="sh" style="color: #dd1144;">"</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">join</span><span class="p">(</span><span class="n" style="color: #333333;">line</span><span class="p">)</span> <span class="o" style="font-weight: 600;">+</span> <span class="sh" style="color: #dd1144;">"</span><span class="se" style="color: #dd1144;">\n</span><span class="sh" style="color: #dd1144;">"</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="92" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

92

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC92" class="line" lang="python">    <span class="n" style="color: #333333;">reference</span><span class="o" style="font-weight: 600;">=</span><span class="nf" style="color: #990000; font-weight: 600;">dedent</span><span class="p">(</span><span class="sa">f</span><span class="sh" style="color: #dd1144;">"""</span><span class="se" style="color: #dd1144;">\</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="93" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

93

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC93" class="line" lang="python"><span class="s" style="color: #dd1144;">        ></span><span class="si" style="color: #dd1144;">{</span><span class="n" style="color: #333333;">reference_name</span><span class="si" style="color: #dd1144;">}</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="94" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

94

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC94" class="line" lang="python"><span class="s" style="color: #dd1144;">        </span><span class="si" style="color: #dd1144;">{</span><span class="n" style="color: #333333;">reference_seq</span><span class="si" style="color: #dd1144;">}</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="95" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC95" class="line" lang="python"><span class="s" style="color: #dd1144;">    </span><span class="sh" style="color: #dd1144;">"""</span><span class="p">)</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="96" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

96

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC96" class="line" lang="python">    <span class="nb" style="color: #0086b3;">dir</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">tmp_path_factory</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">mktemp</span><span class="p">(</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">data</span><span class="sh" style="color: #dd1144;">"</span><span class="p">)</span></span>

</pre></td>

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</td>

<td class="new_line diff-line-num new" data-linenumber="97" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

97

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC97" class="line" lang="python">    <span class="n" style="color: #333333;">vcf_fn</span> <span class="o" style="font-weight: 600;">=</span> <span class="nb" style="color: #0086b3;">dir</span> <span class="o" style="font-weight: 600;">/</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">snps.vcf</span><span class="sh" style="color: #dd1144;">"</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="98" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

98

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC98" class="line" lang="python">    <span class="n" style="color: #333333;">ref_fn</span> <span class="o" style="font-weight: 600;">=</span> <span class="nb" style="color: #0086b3;">dir</span> <span class="o" style="font-weight: 600;">/</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">reference.fasta</span><span class="sh" style="color: #dd1144;">"</span></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="99" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

99

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC99" class="line" lang="python">    <span class="k" style="font-weight: 600;">with</span> <span class="nf" style="color: #990000; font-weight: 600;">open</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_fn</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">w</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span> <span class="k" style="font-weight: 600;">as</span> <span class="n" style="color: #333333;">fh</span><span class="p">:</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="100" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

100

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC100" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">print</span><span class="p">(</span><span class="n" style="color: #333333;">vcf</span><span class="p">,</span> <span class="nb" style="color: #0086b3;">file</span><span class="o" style="font-weight: 600;">=</span><span class="n" style="color: #333333;">fh</span><span class="p">)</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="101" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

101

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC101" class="line" lang="python">    <span class="k" style="font-weight: 600;">with</span> <span class="nf" style="color: #990000; font-weight: 600;">open</span><span class="p">(</span><span class="n" style="color: #333333;">ref_fn</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">w</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span> <span class="k" style="font-weight: 600;">as</span> <span class="n" style="color: #333333;">fh</span><span class="p">:</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="102" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC102" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">print</span><span class="p">(</span><span class="n" style="color: #333333;">reference</span><span class="p">,</span> <span class="nb" style="color: #0086b3;">file</span><span class="o" style="font-weight: 600;">=</span><span class="n" style="color: #333333;">fh</span><span class="p">)</span></span>

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<td class="new_line diff-line-num new" data-linenumber="103" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

103

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC103" class="line" lang="python">    <span class="nf" style="color: #990000; font-weight: 600;">return </span><span class="p">(</span><span class="nf" style="color: #990000; font-weight: 600;">str</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_fn</span><span class="p">),</span> <span class="nf" style="color: #990000; font-weight: 600;">str</span><span class="p">(</span><span class="n" style="color: #333333;">ref_fn</span><span class="p">))</span></span>

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<td class="new_line diff-line-num new" data-linenumber="104" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

104

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC104" class="line" lang="python"></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="105" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

105

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC105" class="line" lang="python"></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="106" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

106

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC106" class="line" lang="python"><span class="k" style="font-weight: 600;">class</span> <span class="nc" style="color: #445588; font-weight: 600;">TestSimpleVcf</span><span class="p">:</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="107" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC107" class="line" lang="python">    <span class="nd">@pytest.fixture</span><span class="p">(</span><span class="n" style="color: #333333;">scope</span><span class="o" style="font-weight: 600;">=</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">class</span><span class="sh" style="color: #dd1144;">"</span><span class="p">)</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="108" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC108" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">data</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">tmp_path_factory</span><span class="p">):</span></span>

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<td class="new_line diff-line-num new" data-linenumber="109" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC109" class="line" lang="python">        <span class="sh" style="color: #dd1144;">"""</span></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="110" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC110" class="line" lang="python"><span class="s" style="color: #dd1144;">        Creates the VCF and reference files (in a temporary location) to be used by</span></span>

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<td class="new_line diff-line-num new" data-linenumber="111" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

111

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC111" class="line" lang="python"><span class="s" style="color: #dd1144;">        the tests in this class.</span></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="112" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

112

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC112" class="line" lang="python"><span class="s" style="color: #dd1144;">        Returns their filenames, as well as information about their contents which</span></span>

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<td class="new_line diff-line-num new" data-linenumber="113" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC113" class="line" lang="python"><span class="s" style="color: #dd1144;">        we can use as comparisons in tests.</span></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="114" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC114" class="line" lang="python"><span class="s" style="color: #dd1144;">        NOTE: this function is only run once - _not_ once per test.</span></span>

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<td class="new_line diff-line-num new" data-linenumber="115" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC115" class="line" lang="python"><span class="s" style="color: #dd1144;">        </span><span class="sh" style="color: #dd1144;">"""</span></span>

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<td class="new_line diff-line-num new" data-linenumber="116" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC116" class="line" lang="python">        <span class="n" style="color: #333333;">sample_names</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">sample_A</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">sample_B</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">sample_C</span><span class="sh" style="color: #dd1144;">"</span><span class="p">]</span></span>

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<td class="new_line diff-line-num new" data-linenumber="117" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC117" class="line" lang="python">        <span class="n" style="color: #333333;">data_lines</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">[</span></span>

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<td class="new_line diff-line-num new" data-linenumber="118" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC118" class="line" lang="python">            <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">5</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>  <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">T</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">C</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>   <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">],</span></span>

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119

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC119" class="line" lang="python">            <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">7</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>  <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">T</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">G</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>   <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">],</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="120" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

120

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC120" class="line" lang="python">            <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">14</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">C</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">T</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>   <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">],</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="121" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

121

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC121" class="line" lang="python">            <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">18</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">C</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">T</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>   <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">],</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="122" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

122

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC122" class="line" lang="python">            <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">28</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">A</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">N</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>   <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">],</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="123" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

123

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC123" class="line" lang="python">            <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">29</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">A</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">N</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>   <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">],</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="124" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

124

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC124" class="line" lang="python">            <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">30</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">A</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">N</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>   <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">],</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="125" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

125

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC125" class="line" lang="python">            <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">33</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">A</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">C,G</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">2</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">],</span></span>

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<td class="new_line diff-line-num new" data-linenumber="126" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

126

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC126" class="line" lang="python">            <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">39</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">C</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">T</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>   <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">],</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="127" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

127

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC127" class="line" lang="python">            <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">42</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">G</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">A</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>   <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">],</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="128" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

128

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC128" class="line" lang="python">            <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">43</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">A</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">T</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>   <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">],</span></span>

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<td class="new_line diff-line-num new" data-linenumber="129" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

129

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC129" class="line" lang="python">        <span class="p">]</span></span>

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<td class="new_line diff-line-num new" data-linenumber="130" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

130

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC130" class="line" lang="python">        <span class="n" style="color: #333333;">positions</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">[</span><span class="nf" style="color: #990000; font-weight: 600;">int</span><span class="p">(</span><span class="n" style="color: #333333;">line</span><span class="p">[</span><span class="mi" style="color: #009999;">1</span><span class="p">])</span> <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">line</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">data_lines</span><span class="p">]</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="131" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

131

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC131" class="line" lang="python">        <span class="n" style="color: #333333;">reference_seq</span> <span class="o" style="font-weight: 600;">=</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">AAAAAAAAAATGCCCTGCGGGTAAAAAAAAAAAAACTACTTGACCATAAA</span><span class="sh" style="color: #dd1144;">'</span></span>

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<td class="new_line diff-line-num new" data-linenumber="132" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

132

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC132" class="line" lang="python">        <span class="n" style="color: #333333;">filenames</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">write_data</span><span class="p">(</span><span class="n" style="color: #333333;">tmp_path_factory</span><span class="p">,</span> <span class="n" style="color: #333333;">sample_names</span><span class="p">,</span> <span class="n" style="color: #333333;">data_lines</span><span class="p">,</span> <span class="n" style="color: #333333;">reference_seq</span><span class="p">)</span></span>

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133

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC133" class="line" lang="python">        <span class="k" style="font-weight: 600;">return</span> <span class="p">{</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="134" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

134

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC134" class="line" lang="python">            <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">filenames</span><span class="sh" style="color: #dd1144;">"</span><span class="p">:</span> <span class="n" style="color: #333333;">filenames</span><span class="p">,</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="135" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

135

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC135" class="line" lang="python">            <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">positions</span><span class="sh" style="color: #dd1144;">"</span><span class="p">:</span> <span class="n" style="color: #333333;">positions</span><span class="p">,</span></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="136" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

136

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC136" class="line" lang="python">            <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">data_lines</span><span class="sh" style="color: #dd1144;">"</span><span class="p">:</span> <span class="n" style="color: #333333;">data_lines</span><span class="p">,</span></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="137" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

137

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC137" class="line" lang="python">            <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">sample_names</span><span class="sh" style="color: #dd1144;">"</span><span class="p">:</span> <span class="n" style="color: #333333;">sample_names</span><span class="p">,</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="138" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

138

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC138" class="line" lang="python">            <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">reference_seq</span><span class="sh" style="color: #dd1144;">"</span><span class="p">:</span> <span class="n" style="color: #333333;">reference_seq</span><span class="p">,</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="139" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

139

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC139" class="line" lang="python">        <span class="p">}</span></span>

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<td class="new_line diff-line-num new" data-linenumber="140" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

140

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC140" class="line" lang="python"></span>

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<td class="new_line diff-line-num new" data-linenumber="141" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

141

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC141" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">test_mutation_structure</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">data</span><span class="p">):</span></span>

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<td class="new_line diff-line-num new" data-linenumber="142" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

142

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC142" class="line" lang="python">        <span class="n" style="color: #333333;">vcf_data</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">read_vcf</span><span class="p">(</span><span class="o" style="font-weight: 600;">*</span><span class="n" style="color: #333333;">data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">filenames</span><span class="sh" style="color: #dd1144;">'</span><span class="p">])</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="143" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

143

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC143" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;"># The structure of insertions & sequences is a dict a key for each sample, irregardless of whether</span></span>

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<td class="new_line diff-line-num new" data-linenumber="144" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

144

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC144" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;"># any insertions/mutations are defined for that sample.</span></span>

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<td class="new_line diff-line-num new" data-linenumber="145" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC145" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;"># samples = {'sample_A', 'sample_B', 'sample_C'}</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC146" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="nf" style="color: #990000; font-weight: 600;">set</span><span class="p">(</span><span class="n" style="color: #333333;">data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sample_names</span><span class="sh" style="color: #dd1144;">'</span><span class="p">])</span><span class="o" style="font-weight: 600;">==</span><span class="nf" style="color: #990000; font-weight: 600;">set</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">].</span><span class="nf" style="color: #990000; font-weight: 600;">keys</span><span class="p">()))</span></span>

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<td class="new_line diff-line-num new" data-linenumber="147" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

147

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC147" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="nf" style="color: #990000; font-weight: 600;">set</span><span class="p">(</span><span class="n" style="color: #333333;">data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sample_names</span><span class="sh" style="color: #dd1144;">'</span><span class="p">])</span><span class="o" style="font-weight: 600;">==</span><span class="nf" style="color: #990000; font-weight: 600;">set</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">insertions</span><span class="sh" style="color: #dd1144;">'</span><span class="p">].</span><span class="nf" style="color: #990000; font-weight: 600;">keys</span><span class="p">()))</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC148" class="line" lang="python"></span>

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<td class="new_line diff-line-num new" data-linenumber="149" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC149" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">test_mutation_parsing</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">data</span><span class="p">):</span></span>

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<td class="new_line diff-line-num new" data-linenumber="150" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC150" class="line" lang="python">        <span class="sh" style="color: #dd1144;">"""</span></span>

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<td class="new_line diff-line-num new" data-linenumber="151" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

151

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC151" class="line" lang="python"><span class="s" style="color: #dd1144;">        Test that the correct SNPs (ALTs) are extracted from the VCF for the three samples defined in the VCF</span></span>

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<td class="new_line diff-line-num new" data-linenumber="152" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC152" class="line" lang="python"><span class="s" style="color: #dd1144;">        </span><span class="sh" style="color: #dd1144;">"""</span></span>

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<td class="new_line diff-line-num new" data-linenumber="153" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

153

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC153" class="line" lang="python">        <span class="n" style="color: #333333;">vcf_data</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">read_vcf</span><span class="p">(</span><span class="o" style="font-weight: 600;">*</span><span class="n" style="color: #333333;">data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">filenames</span><span class="sh" style="color: #dd1144;">'</span><span class="p">])</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="154" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

154

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC154" class="line" lang="python">        <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">summarise</span><span class="p">(</span><span class="n" style="color: #333333;">sample</span><span class="p">):</span></span>

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<td class="new_line diff-line-num new" data-linenumber="155" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

155

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC155" class="line" lang="python">            <span class="c1" style="color: #999988; font-style: italic;"># uses 1-based position so we can easily compare with the VCF file</span></span>

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<td class="new_line diff-line-num new" data-linenumber="156" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC156" class="line" lang="python">            <span class="k" style="font-weight: 600;">return</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">,</span><span class="sh" style="color: #dd1144;">"</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">join</span><span class="p">([</span><span class="sa">f</span><span class="sh" style="color: #dd1144;">"</span><span class="si" style="color: #dd1144;">{</span><span class="n" style="color: #333333;">pos</span><span class="o" style="font-weight: 600;">+</span><span class="mi" style="color: #009999;">1</span><span class="si" style="color: #dd1144;">}{</span><span class="n" style="color: #333333;">alt</span><span class="si" style="color: #dd1144;">}</span><span class="sh" style="color: #dd1144;">"</span> <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">pos</span><span class="p">,</span><span class="n" style="color: #333333;">alt</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">vcf_data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="n" style="color: #333333;">sample</span><span class="p">].</span><span class="nf" style="color: #990000; font-weight: 600;">items</span><span class="p">()])</span></span>

</pre></td>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC157" class="line" lang="python"></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC158" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">5C,7G,14T,33C,39T,43T</span><span class="sh" style="color: #dd1144;">"</span><span class="o" style="font-weight: 600;">==</span><span class="nf" style="color: #990000; font-weight: 600;">summarise</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sample_A</span><span class="sh" style="color: #dd1144;">'</span><span class="p">))</span></span>

</pre></td>

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</td>

<td class="new_line diff-line-num new" data-linenumber="159" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

159

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC159" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">5C,7G,14T,33G,42A,43T</span><span class="sh" style="color: #dd1144;">"</span><span class="o" style="font-weight: 600;">==</span><span class="nf" style="color: #990000; font-weight: 600;">summarise</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sample_B</span><span class="sh" style="color: #dd1144;">'</span><span class="p">))</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="160" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

160

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC160" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">5C,18T,28N,29N,30N</span><span class="sh" style="color: #dd1144;">"</span><span class="o" style="font-weight: 600;">==</span><span class="nf" style="color: #990000; font-weight: 600;">summarise</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sample_C</span><span class="sh" style="color: #dd1144;">'</span><span class="p">))</span></span>

</pre></td>

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</td>

<td class="new_line diff-line-num new" data-linenumber="161" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

161

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC161" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="162" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

162

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC162" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">test_no_insertions_parsed</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">data</span><span class="p">):</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="163" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

163

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC163" class="line" lang="python">        <span class="n" style="color: #333333;">vcf_data</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">read_vcf</span><span class="p">(</span><span class="o" style="font-weight: 600;">*</span><span class="n" style="color: #333333;">data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">filenames</span><span class="sh" style="color: #dd1144;">'</span><span class="p">])</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="164" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

164

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC164" class="line" lang="python">        <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">sample</span><span class="p">,</span> <span class="n" style="color: #333333;">ins</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">vcf_data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">insertions</span><span class="sh" style="color: #dd1144;">'</span><span class="p">].</span><span class="nf" style="color: #990000; font-weight: 600;">items</span><span class="p">():</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="165" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

165

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC165" class="line" lang="python">            <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">ins</span><span class="o" style="font-weight: 600;">==</span><span class="p">{})</span></span>

</pre></td>

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</td>

<td class="new_line diff-line-num new" data-linenumber="166" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

166

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC166" class="line" lang="python"></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="167" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

167

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC167" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">test_reference_sequence</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">data</span><span class="p">):</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="168" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

168

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC168" class="line" lang="python">        <span class="n" style="color: #333333;">vcf_data</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">read_vcf</span><span class="p">(</span><span class="o" style="font-weight: 600;">*</span><span class="n" style="color: #333333;">data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">filenames</span><span class="sh" style="color: #dd1144;">'</span><span class="p">])</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="169" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

169

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC169" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">reference_seq</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span><span class="o" style="font-weight: 600;">==</span><span class="n" style="color: #333333;">vcf_data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">reference</span><span class="sh" style="color: #dd1144;">'</span><span class="p">])</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="170" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

170

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC170" class="line" lang="python"></span>

</pre></td>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC171" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">test_positions_with_mutations</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">data</span><span class="p">):</span></span>

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<td class="new_line diff-line-num new" data-linenumber="172" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC172" class="line" lang="python">        <span class="n" style="color: #333333;">vcf_data</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">read_vcf</span><span class="p">(</span><span class="o" style="font-weight: 600;">*</span><span class="n" style="color: #333333;">data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">filenames</span><span class="sh" style="color: #dd1144;">'</span><span class="p">])</span></span>

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<td class="new_line diff-line-num new" data-linenumber="173" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC173" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">positions</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span> <span class="o" style="font-weight: 600;">==</span> <span class="p">[</span><span class="n" style="color: #333333;">pos</span><span class="o" style="font-weight: 600;">+</span><span class="mi" style="color: #009999;">1</span> <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">pos</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">vcf_data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">positions</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]])</span> </span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC174" class="line" lang="python"></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC175" class="line" lang="python"></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC176" class="line" lang="python"><span class="k" style="font-weight: 600;">class</span> <span class="nc" style="color: #445588; font-weight: 600;">TestNoCallsOrMissing</span><span class="p">:</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC177" class="line" lang="python">    <span class="sh" style="color: #dd1144;">"""</span></span>

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<td class="new_line diff-line-num new" data-linenumber="178" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC178" class="line" lang="python"><span class="s" style="color: #dd1144;">    Tests a few overlapping concepts:</span></span>

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<td class="new_line diff-line-num new" data-linenumber="179" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC179" class="line" lang="python"><span class="s" style="color: #dd1144;">    - The genotype field (i.e. within the column of a sample name) may be </span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;"> which results in a</span></span>

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<td class="new_line diff-line-num new" data-linenumber="180" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC180" class="line" lang="python"><span class="s" style="color: #dd1144;">      no call allele. So we call this as SNP(s) changing the REF to N(s). The 4.2 spec refers</span></span>

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<td class="new_line diff-line-num new" data-linenumber="181" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC181" class="line" lang="python"><span class="s" style="color: #dd1144;">      to this as </span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">a call cannot be made for a sample at a given locus</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">. Spec 4.3 defines this</span></span>

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<td class="new_line diff-line-num new" data-linenumber="182" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC182" class="line" lang="python"><span class="s" style="color: #dd1144;">      as </span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">If a call cannot be made for a sample at a given locus, </span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;"> must be specified for each</span></span>

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<td class="new_line diff-line-num new" data-linenumber="183" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC183" class="line" lang="python"><span class="s" style="color: #dd1144;">      missing allele in the GT field (for example ./. for a diploid genotype and . for haploid</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC184" class="line" lang="python"><span class="s" style="color: #dd1144;">      genotype)</span><span class="sh" style="color: #dd1144;">"</span></span>

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<td class="new_line diff-line-num new" data-linenumber="185" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

185

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC185" class="line" lang="python"><span class="s" style="color: #dd1144;">    - The ALT allele may be </span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">*</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">. v4.2. defines this as </span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">missing due to a upstream deletion (sic)</span><span class="sh" style="color: #dd1144;">"</span></span>

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<td class="new_line diff-line-num new" data-linenumber="186" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC186" class="line" lang="python"><span class="s" style="color: #dd1144;">      and 4.3 defines this as </span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">allele missing due to overlapping deletion</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">. Either way we encode</span></span>

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<td class="new_line diff-line-num new" data-linenumber="187" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

187

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC187" class="line" lang="python"><span class="s" style="color: #dd1144;">      this similarly to the no-call above, i.e. changing the REF to N(s). Note that the allele</span></span>

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<td class="new_line diff-line-num new" data-linenumber="188" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

188

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC188" class="line" lang="python"><span class="s" style="color: #dd1144;">      must be the one-character </span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">*</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;"> - this can</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">t appear within other bases.</span></span>

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<td class="new_line diff-line-num new" data-linenumber="189" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

189

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC189" class="line" lang="python"><span class="s" style="color: #dd1144;">    - The ALT allele may be </span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">. This was introduced in version 4.3 as </span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">a MISSING value (no variant)</span><span class="sh" style="color: #dd1144;">"</span></span>

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<td class="new_line diff-line-num new" data-linenumber="190" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC190" class="line" lang="python"><span class="s" style="color: #dd1144;">      So we treat this the same as </span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">*</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;"> above. Again, this must be the entire allele, </span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;"> can</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">t appear</span></span>

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<td class="new_line diff-line-num new" data-linenumber="191" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC191" class="line" lang="python"><span class="s" style="color: #dd1144;">      as part of other bases. Note that while this doesn</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">t exist in v4.2, it is commonly found in</span></span>

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<td class="new_line diff-line-num new" data-linenumber="192" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC192" class="line" lang="python"><span class="s" style="color: #dd1144;">      v4.2 VCF files, e.g. those produced by `snp_sites`.</span></span>

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<td class="new_line diff-line-num new" data-linenumber="193" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC193" class="line" lang="python"><span class="s" style="color: #dd1144;">    </span><span class="sh" style="color: #dd1144;">"""</span></span>

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<td class="new_line diff-line-num new" data-linenumber="194" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC194" class="line" lang="python"></span>

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<td class="new_line diff-line-num new" data-linenumber="195" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC195" class="line" lang="python">    <span class="nd">@pytest.fixture</span><span class="p">(</span><span class="n" style="color: #333333;">scope</span><span class="o" style="font-weight: 600;">=</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">class</span><span class="sh" style="color: #dd1144;">"</span><span class="p">)</span></span>

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<td class="new_line diff-line-num new" data-linenumber="196" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC196" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">data</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">tmp_path_factory</span><span class="p">):</span></span>

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<td class="new_line diff-line-num new" data-linenumber="197" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC197" class="line" lang="python">        <span class="n" style="color: #333333;">reference</span><span class="o" style="font-weight: 600;">=</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">ATCGA</span><span class="sh" style="color: #dd1144;">"</span></span>

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<td class="new_line diff-line-num new" data-linenumber="198" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

198

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC198" class="line" lang="python">        <span class="n" style="color: #333333;">sample_names</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">sample_A</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">sample_B</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">sample_C</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">sample_D</span><span class="sh" style="color: #dd1144;">"</span><span class="p">]</span></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="199" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

199

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC199" class="line" lang="python">        <span class="n" style="color: #333333;">data_lines</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">[</span></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="200" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

200

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC200" class="line" lang="python">            <span class="c1" style="color: #999988; font-style: italic;">## No call alleles</span></span>

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<td class="new_line diff-line-num new" data-linenumber="201" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

201

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC201" class="line" lang="python">            <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">2</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>  <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">T</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">A</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>    <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">],</span> <span class="c1" style="color: #999988; font-style: italic;"># sample A has T2N</span></span>

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<td class="new_line diff-line-num new" data-linenumber="202" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC202" class="line" lang="python">            <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">4</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>  <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GA</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">C</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>   <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">],</span> <span class="c1" style="color: #999988; font-style: italic;"># sample A has GA -> NN</span></span>

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<td class="new_line diff-line-num new" data-linenumber="203" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

203

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC203" class="line" lang="python">            <span class="c1" style="color: #999988; font-style: italic;">## star alleles & dot alleles indicate missing</span></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="204" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC204" class="line" lang="python">            <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">3</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>  <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">C</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">*,G</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>  <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">2</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">],</span> <span class="c1" style="color: #999988; font-style: italic;"># sample A has C->N</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC205" class="line" lang="python">            <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">3</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>  <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">C</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">T,.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>  <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">2</span><span class="sh" style="color: #dd1144;">"</span><span class="p">],</span> <span class="c1" style="color: #999988; font-style: italic;"># sample D has C->N</span></span>

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<td class="new_line diff-line-num new" data-linenumber="206" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC206" class="line" lang="python">            <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">4</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>  <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GA</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.,*</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">2</span><span class="sh" style="color: #dd1144;">"</span><span class="p">],</span> <span class="c1" style="color: #999988; font-style: italic;"># both samples C & D have G->N and A->N</span></span>

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<td class="new_line diff-line-num new" data-linenumber="207" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC207" class="line" lang="python">        <span class="p">]</span></span>

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<td class="new_line diff-line-num new" data-linenumber="208" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC208" class="line" lang="python">        <span class="n" style="color: #333333;">filenames</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">write_data</span><span class="p">(</span><span class="n" style="color: #333333;">tmp_path_factory</span><span class="p">,</span> <span class="n" style="color: #333333;">sample_names</span><span class="p">,</span> <span class="n" style="color: #333333;">data_lines</span><span class="p">,</span> <span class="n" style="color: #333333;">reference</span><span class="p">)</span></span>

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<td class="new_line diff-line-num new" data-linenumber="209" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC209" class="line" lang="python">        <span class="k" style="font-weight: 600;">return</span> <span class="p">{</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">filenames</span><span class="sh" style="color: #dd1144;">"</span><span class="p">:</span> <span class="n" style="color: #333333;">filenames</span><span class="p">}</span></span>

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<td class="new_line diff-line-num new" data-linenumber="210" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC210" class="line" lang="python"></span>

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<td class="new_line diff-line-num new" data-linenumber="211" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC211" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">test_no_call_allele</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">data</span><span class="p">):</span></span>

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<td class="new_line diff-line-num new" data-linenumber="212" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC212" class="line" lang="python">        <span class="n" style="color: #333333;">vcf_data</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">read_vcf</span><span class="p">(</span><span class="o" style="font-weight: 600;">*</span><span class="n" style="color: #333333;">data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">filenames</span><span class="sh" style="color: #dd1144;">'</span><span class="p">])</span></span>

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<td class="new_line diff-line-num new" data-linenumber="213" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC213" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sample_A</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="nf" style="color: #990000; font-weight: 600;">zero_based</span><span class="p">(</span><span class="mi" style="color: #009999;">2</span><span class="p">)]</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">N</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

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<td class="new_line diff-line-num new" data-linenumber="214" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC214" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sample_A</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="nf" style="color: #990000; font-weight: 600;">zero_based</span><span class="p">(</span><span class="mi" style="color: #009999;">4</span><span class="p">)]</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">N</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

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<td class="new_line diff-line-num new" data-linenumber="215" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC215" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sample_A</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="nf" style="color: #990000; font-weight: 600;">zero_based</span><span class="p">(</span><span class="mi" style="color: #009999;">5</span><span class="p">)]</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">N</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

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<td class="new_line diff-line-num new" data-linenumber="216" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC216" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sample_B</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="nf" style="color: #990000; font-weight: 600;">zero_based</span><span class="p">(</span><span class="mi" style="color: #009999;">4</span><span class="p">)]</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">C</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span> </span>

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<td class="new_line diff-line-num new" data-linenumber="217" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC217" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sample_B</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="nf" style="color: #990000; font-weight: 600;">zero_based</span><span class="p">(</span><span class="mi" style="color: #009999;">5</span><span class="p">)]</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">-</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

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<td class="new_line diff-line-num new" data-linenumber="218" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC218" class="line" lang="python"></span>

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<td class="new_line diff-line-num new" data-linenumber="219" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC219" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">test_star_allele</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">data</span><span class="p">):</span></span>

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<td class="new_line diff-line-num new" data-linenumber="220" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC220" class="line" lang="python">        <span class="n" style="color: #333333;">vcf_data</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">read_vcf</span><span class="p">(</span><span class="o" style="font-weight: 600;">*</span><span class="n" style="color: #333333;">data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">filenames</span><span class="sh" style="color: #dd1144;">'</span><span class="p">])</span></span>

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<td class="new_line diff-line-num new" data-linenumber="221" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC221" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sample_A</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="nf" style="color: #990000; font-weight: 600;">zero_based</span><span class="p">(</span><span class="mi" style="color: #009999;">3</span><span class="p">)]</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">N</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

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<td class="new_line diff-line-num new" data-linenumber="222" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC222" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sample_B</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="nf" style="color: #990000; font-weight: 600;">zero_based</span><span class="p">(</span><span class="mi" style="color: #009999;">3</span><span class="p">)]</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">G</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

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<td class="new_line diff-line-num new" data-linenumber="223" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC223" class="line" lang="python"></span>

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<td class="new_line diff-line-num new" data-linenumber="224" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC224" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sample_D</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="nf" style="color: #990000; font-weight: 600;">zero_based</span><span class="p">(</span><span class="mi" style="color: #009999;">4</span><span class="p">)]</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">N</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

</pre></td>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC225" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sample_D</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="nf" style="color: #990000; font-weight: 600;">zero_based</span><span class="p">(</span><span class="mi" style="color: #009999;">5</span><span class="p">)]</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">N</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

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<td class="new_line diff-line-num new" data-linenumber="226" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

226

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC226" class="line" lang="python"></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC227" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">test_dot_allele</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">data</span><span class="p">):</span></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="228" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

228

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC228" class="line" lang="python">        <span class="n" style="color: #333333;">vcf_data</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">read_vcf</span><span class="p">(</span><span class="o" style="font-weight: 600;">*</span><span class="n" style="color: #333333;">data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">filenames</span><span class="sh" style="color: #dd1144;">'</span><span class="p">])</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="229" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC229" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sample_C</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="nf" style="color: #990000; font-weight: 600;">zero_based</span><span class="p">(</span><span class="mi" style="color: #009999;">3</span><span class="p">)]</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">T</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="230" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC230" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sample_D</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="nf" style="color: #990000; font-weight: 600;">zero_based</span><span class="p">(</span><span class="mi" style="color: #009999;">3</span><span class="p">)]</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">N</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="231" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC231" class="line" lang="python"></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="232" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC232" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sample_C</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="nf" style="color: #990000; font-weight: 600;">zero_based</span><span class="p">(</span><span class="mi" style="color: #009999;">4</span><span class="p">)]</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">N</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="233" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

233

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC233" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sample_C</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="nf" style="color: #990000; font-weight: 600;">zero_based</span><span class="p">(</span><span class="mi" style="color: #009999;">5</span><span class="p">)]</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">N</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

</pre></td>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC234" class="line" lang="python"></span>

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<td class="new_line diff-line-num new" data-linenumber="235" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC235" class="line" lang="python"></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="236" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC236" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">test_malformed_star_allele</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">tmp_path</span><span class="p">):</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC237" class="line" lang="python">        <span class="sh" style="color: #dd1144;">"""</span><span class="s" style="color: #dd1144;">* must be an entire allele, not together with other bases</span><span class="sh" style="color: #dd1144;">"""</span></span>

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<td class="new_line diff-line-num new" data-linenumber="238" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC238" class="line" lang="python">        <span class="k" style="font-weight: 600;">with</span> <span class="n" style="color: #333333;">pytest</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">raises</span><span class="p">(</span><span class="n" style="color: #333333;">TreeTimeError</span><span class="p">):</span></span>

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<td class="new_line diff-line-num new" data-linenumber="239" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC239" class="line" lang="python">            <span class="nf" style="color: #990000; font-weight: 600;">read_vcf</span><span class="p">(</span><span class="nf" style="color: #990000; font-weight: 600;">create_vcf</span><span class="p">(</span><span class="n" style="color: #333333;">tmp_path</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"""</span><span class="se" style="color: #dd1144;">\</span></span>

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<td class="new_line diff-line-num new" data-linenumber="240" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC240" class="line" lang="python"><span class="s" style="color: #dd1144;">                #CHROM</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">POS</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">ID</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">REF</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">ALT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">QUAL</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">FILTER</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">INFO</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">FORMAT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">sample_A</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">sample_B</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">sample_C</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC241" class="line" lang="python"><span class="s" style="color: #dd1144;">                ##fileformat=VCFv4.3</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC242" class="line" lang="python"><span class="s" style="color: #dd1144;">                1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">5</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">T</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">C*</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">GT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC243" class="line" lang="python"><span class="s" style="color: #dd1144;">            </span><span class="sh" style="color: #dd1144;">"""</span><span class="p">))</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC244" class="line" lang="python"></span>

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<td class="new_line diff-line-num new" data-linenumber="245" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC245" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">test_malformed_dot_allele</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">tmp_path</span><span class="p">):</span></span>

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<td class="new_line diff-line-num new" data-linenumber="246" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC246" class="line" lang="python">        <span class="sh" style="color: #dd1144;">"""</span><span class="s" style="color: #dd1144;">. must be an entire allele, not together with other bases</span><span class="sh" style="color: #dd1144;">"""</span></span>

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<td class="new_line diff-line-num new" data-linenumber="247" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC247" class="line" lang="python">        <span class="k" style="font-weight: 600;">with</span> <span class="n" style="color: #333333;">pytest</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">raises</span><span class="p">(</span><span class="n" style="color: #333333;">TreeTimeError</span><span class="p">):</span></span>

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<td class="new_line diff-line-num new" data-linenumber="248" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC248" class="line" lang="python">            <span class="nf" style="color: #990000; font-weight: 600;">read_vcf</span><span class="p">(</span><span class="nf" style="color: #990000; font-weight: 600;">create_vcf</span><span class="p">(</span><span class="n" style="color: #333333;">tmp_path</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"""</span><span class="se" style="color: #dd1144;">\</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC250" class="line" lang="python"><span class="s" style="color: #dd1144;">                ##fileformat=VCFv4.3</span></span>

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<td class="new_line diff-line-num new" data-linenumber="251" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC251" class="line" lang="python"><span class="s" style="color: #dd1144;">                1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">5</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">T</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">C.,G</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">GT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC252" class="line" lang="python"><span class="s" style="color: #dd1144;">            </span><span class="sh" style="color: #dd1144;">"""</span><span class="p">))</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC254" class="line" lang="python"></span>

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<td class="new_line diff-line-num new" data-linenumber="255" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC255" class="line" lang="python"><span class="k" style="font-weight: 600;">class</span> <span class="nc" style="color: #445588; font-weight: 600;">TestVcfSpecExamples</span><span class="p">:</span></span>

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<td class="new_line diff-line-num new" data-linenumber="256" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC256" class="line" lang="python">    <span class="sh" style="color: #dd1144;">"""</span></span>

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<td class="new_line diff-line-num new" data-linenumber="257" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC257" class="line" lang="python"><span class="s" style="color: #dd1144;">    Test the examples provided in the VCF specs. Note that the examples</span></span>

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<td class="new_line diff-line-num new" data-linenumber="258" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC258" class="line" lang="python"><span class="s" style="color: #dd1144;">    aren</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">t provided as per-sample VCF files, so there</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">s a bit of interpretation</span></span>

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<td class="new_line diff-line-num new" data-linenumber="259" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC259" class="line" lang="python"><span class="s" style="color: #dd1144;">    required to create the example data. Note that the actual `test_<name>`</span></span>

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<td class="new_line diff-line-num new" data-linenumber="260" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC260" class="line" lang="python"><span class="s" style="color: #dd1144;">    methods are added dynamically after the class definition.</span></span>

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<td class="new_line diff-line-num new" data-linenumber="261" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC261" class="line" lang="python"><span class="s" style="color: #dd1144;">    </span><span class="sh" style="color: #dd1144;">"""</span></span>

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<td class="new_line diff-line-num new" data-linenumber="262" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC262" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">create</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">tmp_path</span><span class="p">,</span> <span class="nb" style="color: #0086b3;">input</span><span class="p">):</span></span>

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<td class="new_line diff-line-num new" data-linenumber="263" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC263" class="line" lang="python">        <span class="n" style="color: #333333;">lines</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">##fileformat=VCFv4.2</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="c1" style="color: #999988; font-style: italic;"># Actual version may differ, but we don't parse this so it doesn't matter (yet)</span></span>

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<td class="new_line diff-line-num new" data-linenumber="264" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC264" class="line" lang="python">            <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">##contig=<ID=1,length=50></span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span></span>

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<td class="new_line diff-line-num new" data-linenumber="265" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

265

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC265" class="line" lang="python">            <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">##FORMAT=<ID=GT,Number=1,Type=String,Description=</span><span class="se" style="color: #dd1144;">\"</span><span class="s" style="color: #dd1144;">Genotype</span><span class="se" style="color: #dd1144;">\"</span><span class="s" style="color: #dd1144;">></span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span></span>

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<td class="new_line diff-line-num new" data-linenumber="266" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC266" class="line" lang="python">            <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">#CHROM</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">POS</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">ID</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">REF</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">ALT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">QUAL</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">FILTER</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">INFO</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">FORMAT</span><span class="se" style="color: #dd1144;">\t</span><span class="sh" style="color: #dd1144;">"</span> <span class="o" style="font-weight: 600;">+</span> <span class="sh" style="color: #dd1144;">"</span><span class="se" style="color: #dd1144;">\t</span><span class="sh" style="color: #dd1144;">"</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">join</span><span class="p">(</span><span class="nb" style="color: #0086b3;">input</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">samples</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]),</span></span>

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<td class="new_line diff-line-num new" data-linenumber="267" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC267" class="line" lang="python">        <span class="p">]</span></span>

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<td class="new_line diff-line-num new" data-linenumber="268" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC268" class="line" lang="python">        <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">d</span> <span class="ow" style="font-weight: 600;">in</span> <span class="nb" style="color: #0086b3;">input</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">data</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]:</span></span>

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<td class="new_line diff-line-num new" data-linenumber="269" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC269" class="line" lang="python">            <span class="n" style="color: #333333;">lines</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">append</span><span class="p">(</span><span class="sa">f</span><span class="sh" style="color: #dd1144;">"</span><span class="si" style="color: #dd1144;">{</span><span class="n" style="color: #333333;">d</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">chrom</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span><span class="si" style="color: #dd1144;">}</span><span class="se" style="color: #dd1144;">\t</span><span class="si" style="color: #dd1144;">{</span><span class="n" style="color: #333333;">d</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">pos</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span><span class="si" style="color: #dd1144;">}</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="si" style="color: #dd1144;">{</span><span class="n" style="color: #333333;">d</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">ref</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span><span class="si" style="color: #dd1144;">}</span><span class="se" style="color: #dd1144;">\t</span><span class="si" style="color: #dd1144;">{</span><span class="n" style="color: #333333;">d</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">alt</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span><span class="si" style="color: #dd1144;">}</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">GT</span><span class="se" style="color: #dd1144;">\t</span><span class="sh" style="color: #dd1144;">"</span> <span class="o" style="font-weight: 600;">+</span> <span class="sh" style="color: #dd1144;">"</span><span class="se" style="color: #dd1144;">\t</span><span class="sh" style="color: #dd1144;">"</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">join</span><span class="p">([</span><span class="nf" style="color: #990000; font-weight: 600;">str</span><span class="p">(</span><span class="n" style="color: #333333;">x</span><span class="p">)</span> <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">x</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">d</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">values</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]]))</span></span>

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<td class="new_line diff-line-num new" data-linenumber="270" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC270" class="line" lang="python">        <span class="k" style="font-weight: 600;">return</span> <span class="nf" style="color: #990000; font-weight: 600;">create_vcf</span><span class="p">(</span><span class="n" style="color: #333333;">tmp_path</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="se" style="color: #dd1144;">\n</span><span class="sh" style="color: #dd1144;">"</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">join</span><span class="p">(</span><span class="n" style="color: #333333;">lines</span><span class="p">))</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC271" class="line" lang="python"></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC272" class="line" lang="python">    <span class="nd">@staticmethod</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC274" class="line" lang="python">        <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">test</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">tmp_path</span><span class="p">):</span></span>

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<td class="new_line diff-line-num new" data-linenumber="275" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC275" class="line" lang="python">            <span class="n" style="color: #333333;">vcf</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">read_vcf</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">create</span><span class="p">(</span><span class="n" style="color: #333333;">tmp_path</span><span class="p">,</span> <span class="n" style="color: #333333;">example_data</span><span class="p">))</span></span>

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<td class="new_line diff-line-num new" data-linenumber="276" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC276" class="line" lang="python">            <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">sample_name</span><span class="p">,</span> <span class="n" style="color: #333333;">sample_data</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">example_data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">expect_sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">].</span><span class="nf" style="color: #990000; font-weight: 600;">items</span><span class="p">():</span></span>

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<td class="new_line diff-line-num new" data-linenumber="277" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC277" class="line" lang="python">                <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">sample_name</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">vcf</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">])</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="278" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC278" class="line" lang="python">                <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">snp</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">sample_data</span><span class="p">:</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="279" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC279" class="line" lang="python">                    <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="nf" style="color: #990000; font-weight: 600;">len</span><span class="p">(</span><span class="n" style="color: #333333;">snp</span><span class="p">)</span><span class="o" style="font-weight: 600;">==</span><span class="mi" style="color: #009999;">2</span><span class="p">)</span></span>

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<td class="new_line diff-line-num new" data-linenumber="280" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC280" class="line" lang="python">                    <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="n" style="color: #333333;">sample_name</span><span class="p">][</span><span class="nf" style="color: #990000; font-weight: 600;">zero_based</span><span class="p">(</span><span class="nf" style="color: #990000; font-weight: 600;">int</span><span class="p">(</span><span class="n" style="color: #333333;">snp</span><span class="p">[</span><span class="mi" style="color: #009999;">0</span><span class="p">]))]</span> <span class="o" style="font-weight: 600;">==</span> <span class="n" style="color: #333333;">snp</span><span class="p">[</span><span class="mi" style="color: #009999;">1</span><span class="p">])</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC281" class="line" lang="python">                <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="nf" style="color: #990000; font-weight: 600;">len</span><span class="p">(</span><span class="n" style="color: #333333;">vcf</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="n" style="color: #333333;">sample_name</span><span class="p">].</span><span class="nf" style="color: #990000; font-weight: 600;">keys</span><span class="p">())</span> <span class="o" style="font-weight: 600;">==</span> <span class="nf" style="color: #990000; font-weight: 600;">len</span><span class="p">(</span><span class="n" style="color: #333333;">sample_data</span><span class="p">))</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC282" class="line" lang="python">            <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">sample_name</span><span class="p">,</span> <span class="n" style="color: #333333;">sample_data</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">example_data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">expect_insertions</span><span class="sh" style="color: #dd1144;">'</span><span class="p">].</span><span class="nf" style="color: #990000; font-weight: 600;">items</span><span class="p">():</span></span>

</pre></td>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC283" class="line" lang="python">                <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">sample_name</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">vcf</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">insertions</span><span class="sh" style="color: #dd1144;">'</span><span class="p">])</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="284" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC284" class="line" lang="python">                <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">ins</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">sample_data</span><span class="p">:</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="285" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC285" class="line" lang="python">                    <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">insertions</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="n" style="color: #333333;">sample_name</span><span class="p">][</span><span class="nf" style="color: #990000; font-weight: 600;">zero_based</span><span class="p">(</span><span class="nf" style="color: #990000; font-weight: 600;">int</span><span class="p">(</span><span class="n" style="color: #333333;">ins</span><span class="p">[</span><span class="mi" style="color: #009999;">0</span><span class="p">]))]</span> <span class="o" style="font-weight: 600;">==</span> <span class="n" style="color: #333333;">ins</span><span class="p">[</span><span class="mi" style="color: #009999;">1</span><span class="p">:])</span></span>

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<td class="new_line diff-line-num new" data-linenumber="286" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC286" class="line" lang="python">                <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="nf" style="color: #990000; font-weight: 600;">len</span><span class="p">(</span><span class="n" style="color: #333333;">vcf</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">insertions</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="n" style="color: #333333;">sample_name</span><span class="p">].</span><span class="nf" style="color: #990000; font-weight: 600;">keys</span><span class="p">())</span> <span class="o" style="font-weight: 600;">==</span> <span class="nf" style="color: #990000; font-weight: 600;">len</span><span class="p">(</span><span class="n" style="color: #333333;">sample_data</span><span class="p">))</span></span>

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<td class="new_line diff-line-num new" data-linenumber="287" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC287" class="line" lang="python">        <span class="k" style="font-weight: 600;">return</span> <span class="n" style="color: #333333;">test</span></span>

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<td class="new_line diff-line-num new" data-linenumber="288" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC288" class="line" lang="python"></span>

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<td class="new_line diff-line-num new" data-linenumber="289" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC289" class="line" lang="python"><span class="sh" style="color: #dd1144;">"""</span></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="290" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC290" class="line" lang="python"><span class="s" style="color: #dd1144;">-------- comment re: TreeTime</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">s encoding of insertions --------</span></span>

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<td class="new_line diff-line-num new" data-linenumber="291" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC291" class="line" lang="python"></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="292" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC292" class="line" lang="python"><span class="s" style="color: #dd1144;">Give a reference base of </span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">C</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;"> at 1-based position 2, and an</span></span>

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<td class="new_line diff-line-num new" data-linenumber="293" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC293" class="line" lang="python"><span class="s" style="color: #dd1144;">insertion _after_ this of </span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">A</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">, TreeTime encodes this as an insertion</span></span>

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<td class="new_line diff-line-num new" data-linenumber="294" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC294" class="line" lang="python"><span class="s" style="color: #dd1144;">of </span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">CA</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;"> at (0-based) position 1. This was unexpected to me,</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="295" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC295" class="line" lang="python"><span class="s" style="color: #dd1144;">I would have expected an insertion of just </span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">A</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">. However I</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">ve written</span></span>

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<td class="new_line diff-line-num new" data-linenumber="296" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC296" class="line" lang="python"><span class="s" style="color: #dd1144;">the tests to conform to TreeTime</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">s existing behaviour (version 0.11.1)</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC297" class="line" lang="python"></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC298" class="line" lang="python"><span class="s" style="color: #dd1144;">---------------------------------------------------------------</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC299" class="line" lang="python"><span class="sh" style="color: #dd1144;">"""</span></span>

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<td class="new_line diff-line-num new" data-linenumber="300" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC300" class="line" lang="python"></span>

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<td class="new_line diff-line-num new" data-linenumber="301" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC301" class="line" lang="python"><span class="n" style="color: #333333;">vcf_spec_data</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">{</span></span>

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<td class="new_line diff-line-num new" data-linenumber="302" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC302" class="line" lang="python">    <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">version_4_2</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">{</span></span>

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<td class="new_line diff-line-num new" data-linenumber="303" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC303" class="line" lang="python">        <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">5_1_1</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">{</span></span>

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<td class="new_line diff-line-num new" data-linenumber="304" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC304" class="line" lang="python">            <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">samples</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">A</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">B</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">C</span><span class="sh" style="color: #dd1144;">'</span><span class="p">],</span></span>

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<td class="new_line diff-line-num new" data-linenumber="305" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC305" class="line" lang="python">            <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">data</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">[</span></span>

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<td class="new_line diff-line-num new" data-linenumber="306" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC306" class="line" lang="python">                <span class="p">{</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">chrom</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="mi" style="color: #009999;">20</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">pos</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="mi" style="color: #009999;">3</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">ref</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">C</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">alt</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">G</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">values</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">[</span><span class="mi" style="color: #009999;">1</span><span class="p">,</span> <span class="mi" style="color: #009999;">0</span><span class="p">,</span> <span class="mi" style="color: #009999;">0</span><span class="p">]},</span></span>

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<td class="new_line diff-line-num new" data-linenumber="307" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC307" class="line" lang="python">                <span class="p">{</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">chrom</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="mi" style="color: #009999;">20</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">pos</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="mi" style="color: #009999;">2</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">ref</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">TC</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">alt</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">T,TCA</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">values</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">[</span><span class="mi" style="color: #009999;">0</span><span class="p">,</span> <span class="mi" style="color: #009999;">1</span><span class="p">,</span> <span class="mi" style="color: #009999;">2</span><span class="p">]}</span></span>

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<td class="new_line diff-line-num new" data-linenumber="308" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC308" class="line" lang="python">            <span class="p">],</span></span>

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<td class="new_line diff-line-num new" data-linenumber="309" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC309" class="line" lang="python">            <span class="c1" style="color: #999988; font-style: italic;"># Note that with TC->TCA, there are no sequence changes (T->T, C->C) but one insertion ("A")</span></span>

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<td class="new_line diff-line-num new" data-linenumber="311" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

311

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC311" class="line" lang="python">            <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">expect_insertions</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">{</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">C</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">3CA</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]}</span> <span class="c1" style="color: #999988; font-style: italic;"># see comment above. Actually only a single base "A" insertion</span></span>

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<td class="new_line diff-line-num new" data-linenumber="312" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

312

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC312" class="line" lang="python">        <span class="p">},</span></span>

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<td class="new_line diff-line-num new" data-linenumber="313" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC313" class="line" lang="python">        <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">5_1_2</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">{</span></span>

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<td class="new_line diff-line-num new" data-linenumber="314" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

314

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC314" class="line" lang="python">            <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">samples</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">A</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">B</span><span class="sh" style="color: #dd1144;">'</span><span class="p">],</span></span>

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<td class="new_line diff-line-num new" data-linenumber="315" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

315

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC315" class="line" lang="python">            <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">data</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">[</span></span>

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<td class="new_line diff-line-num new" data-linenumber="316" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

316

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC316" class="line" lang="python">                <span class="p">{</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">chrom</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="mi" style="color: #009999;">20</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">pos</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="mi" style="color: #009999;">2</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">ref</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">TC</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">alt</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">TG,T</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">values</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">[</span><span class="mi" style="color: #009999;">1</span><span class="p">,</span><span class="mi" style="color: #009999;">2</span><span class="p">]}</span></span>

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<td class="new_line diff-line-num new" data-linenumber="317" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

317

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC317" class="line" lang="python">            <span class="p">],</span></span>

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<td class="new_line diff-line-num new" data-linenumber="318" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

318

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC318" class="line" lang="python">            <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">expect_sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">{</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">A</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">3G</span><span class="sh" style="color: #dd1144;">'</span><span class="p">],</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">B</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">3-</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]},</span></span>

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<td class="new_line diff-line-num new" data-linenumber="319" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

319

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC319" class="line" lang="python">            <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">expect_insertions</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">{}</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC320" class="line" lang="python">        <span class="p">},</span></span>

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<td class="new_line diff-line-num new" data-linenumber="321" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

321

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC321" class="line" lang="python">        <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">5_1_3</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">{</span></span>

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<td class="new_line diff-line-num new" data-linenumber="322" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC322" class="line" lang="python">            <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">samples</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">A</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">B</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">C</span><span class="sh" style="color: #dd1144;">'</span><span class="p">],</span></span>

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<td class="new_line diff-line-num new" data-linenumber="323" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC323" class="line" lang="python">            <span class="c1" style="color: #999988; font-style: italic;">## This example is quite hard to understand for sample A. The alignment provided indicates that</span></span>

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<td class="new_line diff-line-num new" data-linenumber="324" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

324

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC324" class="line" lang="python">            <span class="c1" style="color: #999988; font-style: italic;">## TCG -> T-G is encoded as "ref: TCG, alt: TG". But without aligning the alt to the ref, the only</span></span>

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<td class="new_line diff-line-num new" data-linenumber="325" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

325

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC325" class="line" lang="python">            <span class="c1" style="color: #999988; font-style: italic;">## sane interpretation of this is 2 changes: C->G and G->-. This is what the spec means by</span></span>

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<td class="new_line diff-line-num new" data-linenumber="326" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC326" class="line" lang="python">            <span class="c1" style="color: #999988; font-style: italic;">## "the molecular equivalence explicitly listed above in the per-base alignment is discarded so the</span></span>

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<td class="new_line diff-line-num new" data-linenumber="327" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

327

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC327" class="line" lang="python">            <span class="c1" style="color: #999988; font-style: italic;">## actual placement of equivalent g isn't retained" (also explained in example 5.2.4)</span></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="328" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC328" class="line" lang="python">            <span class="c1" style="color: #999988; font-style: italic;">## Similarly, for sample C, the actual event is described as "A base is inserted wrt the reference</span></span>

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<td class="new_line diff-line-num new" data-linenumber="329" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC329" class="line" lang="python">            <span class="c1" style="color: #999988; font-style: italic;">## sequence" but the way the VCF file reads we are going to have a SNP (G->A) + a insertion (G)</span></span>

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<td class="new_line diff-line-num new" data-linenumber="330" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC330" class="line" lang="python">            <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">data</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">[</span></span>

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<td class="new_line diff-line-num new" data-linenumber="331" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC331" class="line" lang="python">                <span class="p">{</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">chrom</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="mi" style="color: #009999;">20</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">pos</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="mi" style="color: #009999;">2</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">ref</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">TCG</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">alt</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">TG,T,TCAG</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">values</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">[</span><span class="mi" style="color: #009999;">1</span><span class="p">,</span><span class="mi" style="color: #009999;">2</span><span class="p">,</span><span class="mi" style="color: #009999;">3</span><span class="p">]}</span></span>

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<td class="new_line diff-line-num new" data-linenumber="332" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC332" class="line" lang="python">            <span class="p">],</span></span>

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<td class="new_line diff-line-num new" data-linenumber="333" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC333" class="line" lang="python">            <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">expect_sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">{</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">A</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">3G</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">4-</span><span class="sh" style="color: #dd1144;">'</span><span class="p">],</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">B</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">3-</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">4-</span><span class="sh" style="color: #dd1144;">'</span><span class="p">],</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">C</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">4A</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]},</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC334" class="line" lang="python">            <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">expect_insertions</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">{</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">C</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">4AG</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]}</span> <span class="c1" style="color: #999988; font-style: italic;"># See comment above</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC335" class="line" lang="python">        <span class="p">},</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC336" class="line" lang="python">        <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">5_2_1</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">{</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC337" class="line" lang="python">            <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">samples</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">A</span><span class="sh" style="color: #dd1144;">'</span><span class="p">],</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC338" class="line" lang="python">            <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">data</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">[</span></span>

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<td class="new_line diff-line-num new" data-linenumber="339" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC339" class="line" lang="python">                <span class="p">{</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">chrom</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="mi" style="color: #009999;">20</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">pos</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="mi" style="color: #009999;">3</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">ref</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">C</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">alt</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">T</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">values</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">[</span><span class="mi" style="color: #009999;">1</span><span class="p">]}</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC340" class="line" lang="python">            <span class="p">],</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC341" class="line" lang="python">            <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">expect_sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">{</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">A</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">3T</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]},</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC342" class="line" lang="python">            <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">expect_insertions</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">{}</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC343" class="line" lang="python">        <span class="p">},</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC344" class="line" lang="python">        <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">5_2_2</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">{</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC345" class="line" lang="python">            <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">samples</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">A</span><span class="sh" style="color: #dd1144;">'</span><span class="p">],</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC346" class="line" lang="python">            <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">data</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">[</span></span>

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<td class="new_line diff-line-num new" data-linenumber="347" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

347

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC347" class="line" lang="python">                <span class="p">{</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">chrom</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="mi" style="color: #009999;">20</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">pos</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="mi" style="color: #009999;">3</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">ref</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">C</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">alt</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">CTAG</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">values</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">[</span><span class="mi" style="color: #009999;">1</span><span class="p">]}</span></span>

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<td class="new_line diff-line-num new" data-linenumber="348" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

348

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC348" class="line" lang="python">            <span class="p">],</span></span>

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<td class="new_line diff-line-num new" data-linenumber="349" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

349

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC349" class="line" lang="python">            <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">expect_sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">{},</span></span>

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<td class="new_line diff-line-num new" data-linenumber="350" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

350

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC350" class="line" lang="python">            <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">expect_insertions</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">{</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">A</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">3CTAG</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]}</span> <span class="c1" style="color: #999988; font-style: italic;"># See comment above</span></span>

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351

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC351" class="line" lang="python">        <span class="p">},</span></span>

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<td class="new_line diff-line-num new" data-linenumber="352" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

352

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC352" class="line" lang="python">        <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">5_2_3</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">{</span></span>

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353

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC353" class="line" lang="python">            <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">samples</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">A</span><span class="sh" style="color: #dd1144;">'</span><span class="p">],</span></span>

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354

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC354" class="line" lang="python">            <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">data</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">[</span></span>

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<td class="new_line diff-line-num new" data-linenumber="355" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC355" class="line" lang="python">                <span class="p">{</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">chrom</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="mi" style="color: #009999;">20</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">pos</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="mi" style="color: #009999;">2</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">ref</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">TCG</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">alt</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">T</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">values</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">[</span><span class="mi" style="color: #009999;">1</span><span class="p">]}</span></span>

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356

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC356" class="line" lang="python">            <span class="p">],</span></span>

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<td class="new_line diff-line-num new" data-linenumber="357" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC357" class="line" lang="python">            <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">expect_sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">{</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">A</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">3-</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">4-</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]},</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC358" class="line" lang="python">            <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">expect_insertions</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">{}</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC359" class="line" lang="python">        <span class="p">},</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC360" class="line" lang="python">    <span class="p">}</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC361" class="line" lang="python"><span class="p">}</span></span>

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<td class="new_line diff-line-num new" data-linenumber="362" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC362" class="line" lang="python"><span class="c1" style="color: #999988; font-style: italic;"># dynamically create a test for each example in the above data (by adding methods to the class)</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC363" class="line" lang="python"><span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">spec_version</span><span class="p">,</span> <span class="n" style="color: #333333;">spec_data</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">vcf_spec_data</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">items</span><span class="p">():</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC364" class="line" lang="python">    <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">example_key</span><span class="p">,</span> <span class="n" style="color: #333333;">example_data</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">spec_data</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">items</span><span class="p">():</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC365" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">setattr</span><span class="p">(</span><span class="n" style="color: #333333;">TestVcfSpecExamples</span><span class="p">,</span> <span class="sa">f</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">test_</span><span class="si" style="color: #dd1144;">{</span><span class="n" style="color: #333333;">spec_version</span><span class="si" style="color: #dd1144;">}</span><span class="s" style="color: #dd1144;">_example_</span><span class="si" style="color: #dd1144;">{</span><span class="n" style="color: #333333;">example_key</span><span class="si" style="color: #dd1144;">}</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="n" style="color: #333333;">TestVcfSpecExamples</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">add_test</span><span class="p">(</span><span class="n" style="color: #333333;">example_data</span><span class="p">))</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC366" class="line" lang="python"></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC367" class="line" lang="python"></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC368" class="line" lang="python"><span class="k" style="font-weight: 600;">class</span> <span class="nc" style="color: #445588; font-weight: 600;">TestMutationAndInsertion</span><span class="p">:</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC369" class="line" lang="python">    <span class="sh" style="color: #dd1144;">"""</span></span>

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<td class="new_line diff-line-num new" data-linenumber="370" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC370" class="line" lang="python"><span class="s" style="color: #dd1144;">    Tests the situation where a reference base is mutated _and_ there</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">s an insertion</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC371" class="line" lang="python"><span class="s" style="color: #dd1144;">    </span><span class="sh" style="color: #dd1144;">"""</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC372" class="line" lang="python"></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC373" class="line" lang="python">    <span class="nd">@pytest.fixture</span><span class="p">(</span><span class="n" style="color: #333333;">scope</span><span class="o" style="font-weight: 600;">=</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">class</span><span class="sh" style="color: #dd1144;">"</span><span class="p">)</span></span>

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<td class="new_line diff-line-num new" data-linenumber="374" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC374" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">data</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">tmp_path_factory</span><span class="p">):</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC375" class="line" lang="python">        <span class="n" style="color: #333333;">reference</span><span class="o" style="font-weight: 600;">=</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">ATCGA</span><span class="sh" style="color: #dd1144;">"</span></span>

</pre></td>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC376" class="line" lang="python">        <span class="n" style="color: #333333;">sample_names</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">sample_A</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">sample_B</span><span class="sh" style="color: #dd1144;">"</span><span class="p">]</span></span>

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<td class="new_line diff-line-num new" data-linenumber="377" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC377" class="line" lang="python">        <span class="n" style="color: #333333;">data_lines</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">[</span></span>

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<td class="new_line diff-line-num new" data-linenumber="378" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

378

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC378" class="line" lang="python">            <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">2</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>  <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">T</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GA</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>    <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">],</span> <span class="c1" style="color: #999988; font-style: italic;"># sample A has both a C->G mutation _and_ a subsequent "A" insertion</span></span>

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<td class="new_line diff-line-num new" data-linenumber="379" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC379" class="line" lang="python">            <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">3</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>  <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">CGA</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">NTTTA,CCGT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>   <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">2</span><span class="sh" style="color: #dd1144;">"</span><span class="p">],</span> <span class="c1" style="color: #999988; font-style: italic;"># complex! Both samples have multiple mutations + an insertion</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC380" class="line" lang="python">        <span class="p">]</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC381" class="line" lang="python">        <span class="n" style="color: #333333;">filenames</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">write_data</span><span class="p">(</span><span class="n" style="color: #333333;">tmp_path_factory</span><span class="p">,</span> <span class="n" style="color: #333333;">sample_names</span><span class="p">,</span> <span class="n" style="color: #333333;">data_lines</span><span class="p">,</span> <span class="n" style="color: #333333;">reference</span><span class="p">)</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC382" class="line" lang="python">        <span class="k" style="font-weight: 600;">return</span> <span class="p">{</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">filenames</span><span class="sh" style="color: #dd1144;">"</span><span class="p">:</span> <span class="n" style="color: #333333;">filenames</span><span class="p">}</span></span>

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383

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC383" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="384" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

384

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC384" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">test_single_ref_base_mutation_and_insertion</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">data</span><span class="p">):</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="385" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

385

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC385" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;"># This case was missed in treetime 0.11.1</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="386" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

386

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC386" class="line" lang="python">        <span class="n" style="color: #333333;">vcf_data</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">read_vcf</span><span class="p">(</span><span class="o" style="font-weight: 600;">*</span><span class="n" style="color: #333333;">data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">filenames</span><span class="sh" style="color: #dd1144;">'</span><span class="p">])</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="387" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

387

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC387" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sample_A</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="nf" style="color: #990000; font-weight: 600;">zero_based</span><span class="p">(</span><span class="mi" style="color: #009999;">2</span><span class="p">)]</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">G</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="388" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

388

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC388" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">insertions</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sample_A</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="nf" style="color: #990000; font-weight: 600;">zero_based</span><span class="p">(</span><span class="mi" style="color: #009999;">2</span><span class="p">)]</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">GA</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span> <span class="c1" style="color: #999988; font-style: italic;"># see comment above re: insertion encoding</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="389" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

389

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC389" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="390" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

390

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC390" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">test_multi_ref_base_mutations_and_insertion</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">data</span><span class="p">):</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="391" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

391

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC391" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;"># This case was missed in treetime 0.11.1</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="392" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

392

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC392" class="line" lang="python">        <span class="n" style="color: #333333;">vcf_data</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">read_vcf</span><span class="p">(</span><span class="o" style="font-weight: 600;">*</span><span class="n" style="color: #333333;">data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">filenames</span><span class="sh" style="color: #dd1144;">'</span><span class="p">])</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="393" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

393

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC393" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sample_A</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="nf" style="color: #990000; font-weight: 600;">zero_based</span><span class="p">(</span><span class="mi" style="color: #009999;">3</span><span class="p">)]</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">N</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="394" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

394

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC394" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sample_A</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="nf" style="color: #990000; font-weight: 600;">zero_based</span><span class="p">(</span><span class="mi" style="color: #009999;">4</span><span class="p">)]</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">T</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="395" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

395

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC395" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sample_A</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="nf" style="color: #990000; font-weight: 600;">zero_based</span><span class="p">(</span><span class="mi" style="color: #009999;">5</span><span class="p">)]</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">T</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="396" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

396

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC396" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">insertions</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sample_A</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="nf" style="color: #990000; font-weight: 600;">zero_based</span><span class="p">(</span><span class="mi" style="color: #009999;">5</span><span class="p">)]</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">TTA</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span> <span class="c1" style="color: #999988; font-style: italic;"># see comment above re: insertion encoding</span></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="397" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

397

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC397" class="line" lang="python"></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="398" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

398

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC398" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sample_B</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="nf" style="color: #990000; font-weight: 600;">zero_based</span><span class="p">(</span><span class="mi" style="color: #009999;">4</span><span class="p">)]</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">C</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="399" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

399

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC399" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sample_B</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="nf" style="color: #990000; font-weight: 600;">zero_based</span><span class="p">(</span><span class="mi" style="color: #009999;">5</span><span class="p">)]</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">G</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="400" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

400

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC400" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">insertions</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sample_B</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="nf" style="color: #990000; font-weight: 600;">zero_based</span><span class="p">(</span><span class="mi" style="color: #009999;">5</span><span class="p">)]</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">GT</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span> <span class="c1" style="color: #999988; font-style: italic;"># see comment above re: insertion encoding</span></span>

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<td class="new_line diff-line-num new" data-linenumber="401" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

401

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC401" class="line" lang="python"></span>

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<td class="new_line diff-line-num new" data-linenumber="402" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

402

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC402" class="line" lang="python"><span class="k" style="font-weight: 600;">class</span> <span class="nc" style="color: #445588; font-weight: 600;">TestMetadataParsing</span><span class="p">:</span></span>

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<td class="new_line diff-line-num new" data-linenumber="403" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

403

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC403" class="line" lang="python">        </span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="404" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

404

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC404" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">test_simple_haploid</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">tmp_path</span><span class="p">):</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="405" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

405

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC405" class="line" lang="python">        <span class="n" style="color: #333333;">data</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">read_vcf</span><span class="p">(</span><span class="nf" style="color: #990000; font-weight: 600;">create_vcf</span><span class="p">(</span><span class="n" style="color: #333333;">tmp_path</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"""</span><span class="se" style="color: #dd1144;">\</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="406" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

406

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC406" class="line" lang="python"><span class="s" style="color: #dd1144;">            ##fileformat=VCFv4.3</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="407" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

407

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC407" class="line" lang="python"><span class="s" style="color: #dd1144;">            #CHROM</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">POS</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">ID</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">REF</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">ALT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">QUAL</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">FILTER</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">INFO</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">FORMAT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">sample_A</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">sample_B</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">sample_C</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="408" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC408" class="line" lang="python"><span class="s" style="color: #dd1144;">            1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">5</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">T</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">C</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">GT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span></span>

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<td class="new_line diff-line-num new" data-linenumber="409" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC409" class="line" lang="python"><span class="s" style="color: #dd1144;">            1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">6</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">T</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">C</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">GT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1</span></span>

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<td class="new_line diff-line-num new" data-linenumber="410" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

410

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC410" class="line" lang="python"><span class="s" style="color: #dd1144;">        </span><span class="sh" style="color: #dd1144;">"""</span><span class="p">))</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="411" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

411

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC411" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">metadata</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">chrom</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="412" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

412

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC412" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">metadata</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">ploidy</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span><span class="o" style="font-weight: 600;">==</span><span class="mi" style="color: #009999;">1</span><span class="p">)</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="413" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

413

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC413" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">metadata</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">meta_lines</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span><span class="o" style="font-weight: 600;">==</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">##fileformat=VCFv4.3</span><span class="sh" style="color: #dd1144;">'</span><span class="p">])</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="414" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

414

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC414" class="line" lang="python"></span>

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<td class="new_line diff-line-num new" data-linenumber="415" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC415" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">test_simple_diploid</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">tmp_path</span><span class="p">):</span></span>

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<td class="new_line diff-line-num new" data-linenumber="416" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC416" class="line" lang="python">        <span class="n" style="color: #333333;">data</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">read_vcf</span><span class="p">(</span><span class="nf" style="color: #990000; font-weight: 600;">create_vcf</span><span class="p">(</span><span class="n" style="color: #333333;">tmp_path</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"""</span><span class="se" style="color: #dd1144;">\</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="417" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC417" class="line" lang="python"><span class="s" style="color: #dd1144;">            ##fileformat=VCFv4.3</span></span>

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418

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC418" class="line" lang="python"><span class="s" style="color: #dd1144;">            ##contig=<ID=1,length=50></span></span>

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419

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC419" class="line" lang="python"><span class="s" style="color: #dd1144;">            ##FORMAT=<ID=GT,Number=1,Type=String,Description=</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">Genotype</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">></span></span>

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<td class="new_line diff-line-num new" data-linenumber="420" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

420

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC420" class="line" lang="python"><span class="s" style="color: #dd1144;">            #CHROM</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">POS</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">ID</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">REF</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">ALT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">QUAL</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">FILTER</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">INFO</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">FORMAT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">sample_A</span></span>

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421

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC421" class="line" lang="python"><span class="s" style="color: #dd1144;">            foo</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">5</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">T</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">C</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">GT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">1/1</span></span>

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422

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC422" class="line" lang="python"><span class="s" style="color: #dd1144;">            foo</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">6</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">T</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">C</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">GT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">.|.</span></span>

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423

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC423" class="line" lang="python"><span class="s" style="color: #dd1144;">        </span><span class="sh" style="color: #dd1144;">"""</span><span class="p">))</span></span>

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424

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC424" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">metadata</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">chrom</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">foo</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

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425

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC425" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">metadata</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">ploidy</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span><span class="o" style="font-weight: 600;">==</span><span class="mi" style="color: #009999;">2</span><span class="p">)</span></span>

</pre></td>

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426

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC426" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">data</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">metadata</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">meta_lines</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span><span class="o" style="font-weight: 600;">==</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">##fileformat=VCFv4.3</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">##contig=<ID=1,length=50></span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">##FORMAT=<ID=GT,Number=1,Type=String,Description=</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">Genotype</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">></span><span class="sh" style="color: #dd1144;">'</span><span class="p">])</span></span>

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427

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC427" class="line" lang="python"></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC428" class="line" lang="python"></span>

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<td class="new_line diff-line-num new" data-linenumber="429" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

429

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC429" class="line" lang="python"></span>

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<td class="new_line diff-line-num new" data-linenumber="430" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

430

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC430" class="line" lang="python">    </span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="431" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

431

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC431" class="line" lang="python"><span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">roundtrip</span><span class="p">(</span><span class="n" style="color: #333333;">tmp_path</span><span class="p">,</span> <span class="n" style="color: #333333;">sample_names</span><span class="p">,</span> <span class="n" style="color: #333333;">data_lines</span><span class="p">,</span> <span class="n" style="color: #333333;">reference</span><span class="p">,</span> <span class="n" style="color: #333333;">meta_lines</span><span class="p">,</span> <span class="n" style="color: #333333;">pass_metadata</span><span class="o" style="font-weight: 600;">=</span><span class="bp" style="color: #999999;">True</span><span class="p">):</span></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="432" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

432

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC432" class="line" lang="python">    <span class="sh" style="color: #dd1144;">"""</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="433" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

433

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC433" class="line" lang="python"><span class="s" style="color: #dd1144;">    Write the provided data to a (temporary) VCF file.</span></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="434" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

434

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC434" class="line" lang="python"><span class="s" style="color: #dd1144;">    Then read it via `read_vcf` and store this as `vcf_a`.</span></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="435" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

435

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC435" class="line" lang="python"><span class="s" style="color: #dd1144;">    Then write this data via `write_vcf` and read it back, storing as `vcf_b`.</span></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="436" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

436

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC436" class="line" lang="python"><span class="s" style="color: #dd1144;">    Returns a tuple of (vcf_a, vcf_b)</span></span>

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<td class="new_line diff-line-num new" data-linenumber="437" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

437

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC437" class="line" lang="python"><span class="s" style="color: #dd1144;">    </span><span class="sh" style="color: #dd1144;">"""</span></span>

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<td class="new_line diff-line-num new" data-linenumber="438" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

438

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC438" class="line" lang="python"></span>

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<td class="new_line diff-line-num new" data-linenumber="439" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

439

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC439" class="line" lang="python">    <span class="nb" style="color: #0086b3;">dir</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">tmp_path</span> <span class="o" style="font-weight: 600;">/</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">data</span><span class="sh" style="color: #dd1144;">'</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="440" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

440

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC440" class="line" lang="python">    <span class="nb" style="color: #0086b3;">dir</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">mkdir</span><span class="p">()</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="441" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

441

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC441" class="line" lang="python">    <span class="n" style="color: #333333;">vcf_filename_a</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">str</span><span class="p">(</span><span class="nb" style="color: #0086b3;">dir</span> <span class="o" style="font-weight: 600;">/</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">a.vcf</span><span class="sh" style="color: #dd1144;">"</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="442" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

442

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC442" class="line" lang="python">    <span class="n" style="color: #333333;">vcf_filename_b</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">str</span><span class="p">(</span><span class="nb" style="color: #0086b3;">dir</span> <span class="o" style="font-weight: 600;">/</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">b.vcf</span><span class="sh" style="color: #dd1144;">"</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="443" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

443

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC443" class="line" lang="python">    <span class="n" style="color: #333333;">reference_filename</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">str</span><span class="p">(</span><span class="nb" style="color: #0086b3;">dir</span> <span class="o" style="font-weight: 600;">/</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">reference.fasta</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

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<td class="new_line diff-line-num new" data-linenumber="444" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

444

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC444" class="line" lang="python"></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="445" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

445

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC445" class="line" lang="python">    <span class="k" style="font-weight: 600;">with</span> <span class="nf" style="color: #990000; font-weight: 600;">open</span><span class="p">(</span><span class="nf" style="color: #990000; font-weight: 600;">str</span><span class="p">(</span><span class="nb" style="color: #0086b3;">dir</span> <span class="o" style="font-weight: 600;">/</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">reference.fasta</span><span class="sh" style="color: #dd1144;">'</span><span class="p">),</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">w</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span> <span class="k" style="font-weight: 600;">as</span> <span class="n" style="color: #333333;">fh</span><span class="p">:</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="446" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

446

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC446" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">print</span><span class="p">(</span><span class="nf" style="color: #990000; font-weight: 600;">dedent</span><span class="p">(</span><span class="sa">f</span><span class="sh" style="color: #dd1144;">"""</span><span class="se" style="color: #dd1144;">\</span></span>

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<td class="new_line diff-line-num new" data-linenumber="447" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

447

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC447" class="line" lang="python"><span class="s" style="color: #dd1144;">            >reference_name</span></span>

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448

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC448" class="line" lang="python"><span class="s" style="color: #dd1144;">            </span><span class="si" style="color: #dd1144;">{</span><span class="n" style="color: #333333;">reference</span><span class="si" style="color: #dd1144;">}</span></span>

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449

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC449" class="line" lang="python"><span class="s" style="color: #dd1144;">        </span><span class="sh" style="color: #dd1144;">"""</span><span class="p">),</span> <span class="nb" style="color: #0086b3;">file</span><span class="o" style="font-weight: 600;">=</span><span class="n" style="color: #333333;">fh</span><span class="p">)</span></span>

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<td class="new_line diff-line-num new" data-linenumber="450" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

450

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC450" class="line" lang="python"></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="451" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

451

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC451" class="line" lang="python">    <span class="k" style="font-weight: 600;">with</span> <span class="nf" style="color: #990000; font-weight: 600;">open</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_filename_a</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">w</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span> <span class="k" style="font-weight: 600;">as</span> <span class="n" style="color: #333333;">fh</span><span class="p">:</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="452" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

452

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC452" class="line" lang="python">        <span class="n" style="color: #333333;">vcf_lines</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">meta_lines</span><span class="p">[:]</span> <span class="o" style="font-weight: 600;">+</span> \</span>

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<td class="new_line diff-line-num new" data-linenumber="453" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

453

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC453" class="line" lang="python">            <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">#CHROM</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">POS</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">ID</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">REF</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">ALT</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">QUAL</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">FILTER</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">INFO</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">FORMAT</span><span class="se" style="color: #dd1144;">\t</span><span class="sh" style="color: #dd1144;">"</span> <span class="o" style="font-weight: 600;">+</span> <span class="sh" style="color: #dd1144;">"</span><span class="se" style="color: #dd1144;">\t</span><span class="sh" style="color: #dd1144;">"</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">join</span><span class="p">(</span><span class="n" style="color: #333333;">sample_names</span><span class="p">)]</span> <span class="o" style="font-weight: 600;">+</span> \</span>

</pre></td>

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454

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC454" class="line" lang="python">            <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="se" style="color: #dd1144;">\t</span><span class="sh" style="color: #dd1144;">"</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">join</span><span class="p">(</span><span class="n" style="color: #333333;">data</span><span class="p">)</span> <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">data</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">data_lines</span><span class="p">]</span></span>

</pre></td>

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</td>

<td class="new_line diff-line-num new" data-linenumber="455" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

455

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC455" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">print</span><span class="p">(</span><span class="sh" style="color: #dd1144;">"</span><span class="se" style="color: #dd1144;">\n</span><span class="sh" style="color: #dd1144;">"</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">join</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_lines</span><span class="p">),</span> <span class="nb" style="color: #0086b3;">file</span><span class="o" style="font-weight: 600;">=</span><span class="n" style="color: #333333;">fh</span><span class="p">)</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="456" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

456

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC456" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="457" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

457

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC457" class="line" lang="python">    <span class="n" style="color: #333333;">vcf_a</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">read_vcf</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_filename_a</span><span class="p">,</span> <span class="n" style="color: #333333;">reference_filename</span><span class="p">)</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="458" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

458

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC458" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="459" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

459

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC459" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">## take this data and write it out as a VCF</span></span>

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<td class="new_line diff-line-num new" data-linenumber="460" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

460

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC460" class="line" lang="python">    <span class="n" style="color: #333333;">tree_dict</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">{</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="n" style="color: #333333;">vcf_a</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">],</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">reference</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="n" style="color: #333333;">vcf_a</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">reference</span><span class="sh" style="color: #dd1144;">'</span><span class="p">],</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">positions</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="n" style="color: #333333;">vcf_a</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">positions</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]}</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="461" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

461

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC461" class="line" lang="python">    <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">pass_metadata</span><span class="p">:</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="462" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

462

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC462" class="line" lang="python">        <span class="n" style="color: #333333;">tree_dict</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">metadata</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">vcf_a</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">metadata</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="463" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

463

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC463" class="line" lang="python">    <span class="nf" style="color: #990000; font-weight: 600;">write_vcf</span><span class="p">(</span><span class="n" style="color: #333333;">tree_dict</span><span class="p">,</span> <span class="n" style="color: #333333;">vcf_filename_b</span><span class="p">)</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="464" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

464

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC464" class="line" lang="python"></span>

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<td class="new_line diff-line-num new" data-linenumber="465" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

465

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC465" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">## then read in this (just-created) VCF</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="466" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

466

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC466" class="line" lang="python">    <span class="n" style="color: #333333;">vcf_b</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">read_vcf</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_filename_b</span><span class="p">,</span> <span class="n" style="color: #333333;">reference_filename</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="467" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

467

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC467" class="line" lang="python"></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="468" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

468

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC468" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">## uncomment the following & run pytest with "-s" to see the contents of the VCF file being written by TreeTime</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="469" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

469

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC469" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;"># print("_________________________________")</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="470" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

470

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC470" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;"># with open(vcf_filename_b) as fh:</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="471" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

471

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC471" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">#     for line in fh:</span></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="472" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

472

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC472" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">#         print(line, end='')</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="473" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

473

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC473" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;"># print("\n_________________________________")</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="474" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

474

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC474" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="475" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

475

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC475" class="line" lang="python">    <span class="nf" style="color: #990000; font-weight: 600;">return </span><span class="p">(</span><span class="n" style="color: #333333;">vcf_a</span><span class="p">,</span> <span class="n" style="color: #333333;">vcf_b</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="476" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

476

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC476" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="477" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

477

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC477" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="478" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

478

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC478" class="line" lang="python"><span class="k" style="font-weight: 600;">class</span> <span class="nc" style="color: #445588; font-weight: 600;">TestWriting</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="479" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

479

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC479" class="line" lang="python">    <span class="sh" style="color: #dd1144;">"""</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="480" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

480

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC480" class="line" lang="python"><span class="s" style="color: #dd1144;">    Write a simple VCF file out (created by hand), parse it with `read_vcf` (called </span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">vcf_a</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="481" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

481

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC481" class="line" lang="python"><span class="s" style="color: #dd1144;">    then write that data out and read it back in (called </span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">vcf_b</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">). vcf_a should equal vcf_b</span></span>

</pre></td>

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482

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC482" class="line" lang="python"><span class="s" style="color: #dd1144;">    for the data we care about.</span></span>

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483

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC483" class="line" lang="python"><span class="s" style="color: #dd1144;">    </span><span class="sh" style="color: #dd1144;">"""</span></span>

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<td class="new_line diff-line-num new" data-linenumber="484" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

484

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC484" class="line" lang="python"></span>

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<td class="new_line diff-line-num new" data-linenumber="485" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

485

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC485" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">test_basic_roundtripping_vcf</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">tmp_path</span><span class="p">):</span></span>

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<td class="new_line diff-line-num new" data-linenumber="486" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

486

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC486" class="line" lang="python">        <span class="p">[</span><span class="n" style="color: #333333;">vcf_a</span><span class="p">,</span> <span class="n" style="color: #333333;">vcf_b</span><span class="p">]</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">roundtrip</span><span class="p">(</span><span class="n" style="color: #333333;">tmp_path</span><span class="p">,</span></span>

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<td class="new_line diff-line-num new" data-linenumber="487" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

487

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC487" class="line" lang="python">            <span class="n" style="color: #333333;">reference</span> <span class="o" style="font-weight: 600;">=</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">ATCGACC</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span></span>

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488

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC488" class="line" lang="python">            <span class="n" style="color: #333333;">meta_lines</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">[</span></span>

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489

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC489" class="line" lang="python">                <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">##fileformat=VCFv4.3</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span></span>

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490

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC490" class="line" lang="python">                <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">##contig=<ID=1,length=7></span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span></span>

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491

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC491" class="line" lang="python">                <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">##FORMAT=<ID=GT,Number=1,Type=String,Description=</span><span class="se" style="color: #dd1144;">\"</span><span class="s" style="color: #dd1144;">Genotype</span><span class="se" style="color: #dd1144;">\"</span><span class="s" style="color: #dd1144;">></span><span class="sh" style="color: #dd1144;">"</span></span>

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492

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC492" class="line" lang="python">            <span class="p">],</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC493" class="line" lang="python">            <span class="n" style="color: #333333;">sample_names</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">sample_A</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">sample_B</span><span class="sh" style="color: #dd1144;">"</span><span class="p">],</span></span>

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494

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC494" class="line" lang="python">            <span class="n" style="color: #333333;">data_lines</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">[</span></span>

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495

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC495" class="line" lang="python">                <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">foo</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">2</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>  <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">T</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">G</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>    <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">],</span></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="496" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

496

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC496" class="line" lang="python">                <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">foo</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">3</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>  <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">C</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GA,*</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">2</span><span class="sh" style="color: #dd1144;">"</span><span class="p">],</span> <span class="c1" style="color: #999988; font-style: italic;"># "A" insertion will be lost on roundtrip!</span></span>

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</td>

<td class="new_line diff-line-num new" data-linenumber="497" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

497

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC497" class="line" lang="python">                <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">foo</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">5</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>  <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">A</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">TC</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>   <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">],</span></span>

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</td>

<td class="new_line diff-line-num new" data-linenumber="498" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

498

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC498" class="line" lang="python">                <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">foo</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">6</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>  <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">CC</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">C</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>   <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">],</span> <span class="c1" style="color: #999988; font-style: italic;"># del of (1-based) pos 7 in sample A</span></span>

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<td class="new_line diff-line-num new" data-linenumber="499" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

499

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC499" class="line" lang="python">            <span class="p">],</span></span>

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<td class="new_line diff-line-num new" data-linenumber="500" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

500

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC500" class="line" lang="python">            <span class="n" style="color: #333333;">pass_metadata</span><span class="o" style="font-weight: 600;">=</span><span class="bp" style="color: #999999;">False</span></span>

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<td class="new_line diff-line-num new" data-linenumber="501" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

501

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC501" class="line" lang="python">        <span class="p">)</span></span>

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<td class="new_line diff-line-num new" data-linenumber="502" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

502

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC502" class="line" lang="python"></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="503" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

503

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC503" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">## reference is certainly the same, the same FASTA file is being used for both read_vcf commands, but check anyway</span></span>

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<td class="new_line diff-line-num new" data-linenumber="504" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

504

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC504" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_a</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">reference</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span><span class="o" style="font-weight: 600;">==</span><span class="n" style="color: #333333;">vcf_a</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">reference</span><span class="sh" style="color: #dd1144;">'</span><span class="p">])</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="505" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

505

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC505" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">## insertions, if there are any, _won't_ be the same because `write_vcf` doesn't read insertions even if they're provided</span></span>

</pre></td>

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</td>

<td class="new_line diff-line-num new" data-linenumber="506" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

506

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC506" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">## as input. Note that vcf_a does have an insertion!</span></span>

</pre></td>

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</td>

<td class="new_line diff-line-num new" data-linenumber="507" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

507

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC507" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="508" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

508

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC508" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">## The meta-lines are different (as expected) and since we are not passing the metadata information to `write_vcf`</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="509" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

509

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC509" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">## we get back the defaults, which differ from the input</span></span>

</pre></td>

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</td>

<td class="new_line diff-line-num new" data-linenumber="510" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

510

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC510" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_a</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">metadata</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">chrom</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span> <span class="o" style="font-weight: 600;">==</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">foo</span><span class="sh" style="color: #dd1144;">"</span> <span class="ow" style="font-weight: 600;">and</span> <span class="n" style="color: #333333;">vcf_b</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">metadata</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">chrom</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span> <span class="o" style="font-weight: 600;">==</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">)</span></span>

</pre></td>

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</td>

<td class="new_line diff-line-num new" data-linenumber="511" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

511

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC511" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_a</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">metadata</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">ploidy</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span> <span class="o" style="font-weight: 600;">==</span> <span class="mi" style="color: #009999;">1</span> <span class="ow" style="font-weight: 600;">and</span> <span class="n" style="color: #333333;">vcf_b</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">metadata</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">ploidy</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span> <span class="o" style="font-weight: 600;">==</span> <span class="mi" style="color: #009999;">2</span><span class="p">)</span></span>

</pre></td>

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</td>

<td class="new_line diff-line-num new" data-linenumber="512" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

512

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC512" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="513" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

513

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC513" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">## positions should be the same (positions are only reflective of data in `sequences`, so the ignoring of insertions is ok)</span></span>

</pre></td>

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</td>

<td class="new_line diff-line-num new" data-linenumber="514" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

514

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC514" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_a</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">positions</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span><span class="o" style="font-weight: 600;">==</span><span class="n" style="color: #333333;">vcf_a</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">positions</span><span class="sh" style="color: #dd1144;">'</span><span class="p">])</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="515" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

515

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC515" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">## check sequences are the same</span></span>

</pre></td>

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</td>

<td class="new_line diff-line-num new" data-linenumber="516" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

516

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC516" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_a</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span><span class="o" style="font-weight: 600;">==</span><span class="n" style="color: #333333;">vcf_b</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">])</span></span>

</pre></td>

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517

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC517" class="line" lang="python"></span>

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<td class="new_line diff-line-num new" data-linenumber="518" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

518

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC518" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">test_basic_roundtripping_vcf_with_metadata</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">tmp_path</span><span class="p">):</span></span>

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<td class="new_line diff-line-num new" data-linenumber="519" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

519

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC519" class="line" lang="python">        <span class="p">[</span><span class="n" style="color: #333333;">vcf_a</span><span class="p">,</span> <span class="n" style="color: #333333;">vcf_b</span><span class="p">]</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">roundtrip</span><span class="p">(</span><span class="n" style="color: #333333;">tmp_path</span><span class="p">,</span></span>

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<td class="new_line diff-line-num new" data-linenumber="520" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

520

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC520" class="line" lang="python">            <span class="n" style="color: #333333;">reference</span> <span class="o" style="font-weight: 600;">=</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">ATCGACC</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span></span>

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521

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC521" class="line" lang="python">            <span class="n" style="color: #333333;">meta_lines</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">[</span></span>

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522

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC522" class="line" lang="python">                <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">##fileformat=VCFv4.3</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span></span>

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523

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC523" class="line" lang="python">                <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">##contig=<ID=1,length=7></span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span></span>

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524

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC524" class="line" lang="python">                <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">##FORMAT=<ID=GT,Number=1,Type=String,Description=</span><span class="se" style="color: #dd1144;">\"</span><span class="s" style="color: #dd1144;">Genotype</span><span class="se" style="color: #dd1144;">\"</span><span class="s" style="color: #dd1144;">></span><span class="sh" style="color: #dd1144;">"</span></span>

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525

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC525" class="line" lang="python">            <span class="p">],</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC526" class="line" lang="python">            <span class="n" style="color: #333333;">sample_names</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">sample_A</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">sample_B</span><span class="sh" style="color: #dd1144;">"</span><span class="p">],</span></span>

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527

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC527" class="line" lang="python">            <span class="n" style="color: #333333;">data_lines</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">[</span></span>

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528

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC528" class="line" lang="python">                <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">2</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>  <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">T</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">G</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>    <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">],</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="529" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

529

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC529" class="line" lang="python">                <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">3</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>  <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">C</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GA,*</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">2</span><span class="sh" style="color: #dd1144;">"</span><span class="p">],</span> <span class="c1" style="color: #999988; font-style: italic;"># "A" insertion will be lost on roundtrip!</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="530" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

530

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC530" class="line" lang="python">                <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">5</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>  <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">A</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">TC</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>   <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">],</span></span>

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<td class="new_line diff-line-num new" data-linenumber="531" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

531

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC531" class="line" lang="python">                <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">6</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>  <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">CC</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">C</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span>   <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">"</span><span class="p">],</span> <span class="c1" style="color: #999988; font-style: italic;"># del of (1-based) pos 7 in sample A</span></span>

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<td class="new_line diff-line-num new" data-linenumber="532" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

532

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC532" class="line" lang="python">            <span class="p">],</span></span>

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<td class="new_line diff-line-num new" data-linenumber="533" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

533

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC533" class="line" lang="python">            <span class="n" style="color: #333333;">pass_metadata</span><span class="o" style="font-weight: 600;">=</span><span class="bp" style="color: #999999;">True</span></span>

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<td class="new_line diff-line-num new" data-linenumber="534" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

534

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC534" class="line" lang="python">        <span class="p">)</span></span>

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<td class="new_line diff-line-num new" data-linenumber="535" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

535

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC535" class="line" lang="python"></span>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="536" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

536

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC536" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">## reference is certainly the same, the same FASTA file is being used for both read_vcf commands, but check anyway</span></span>

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<td class="new_line diff-line-num new" data-linenumber="537" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

537

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC537" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_a</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">reference</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span><span class="o" style="font-weight: 600;">==</span><span class="n" style="color: #333333;">vcf_a</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">reference</span><span class="sh" style="color: #dd1144;">'</span><span class="p">])</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="538" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

538

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC538" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">## insertions, if there are any, _won't_ be the same because `write_vcf` doesn't read insertions even if they're provided</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="539" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

539

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC539" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">## as input. Note that vcf_a does have an insertion!</span></span>

</pre></td>

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</td>

<td class="new_line diff-line-num new" data-linenumber="540" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

540

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC540" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="541" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

541

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC541" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">## The meta-lines are different (as expected) but the chrom + ploidy should be the same</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="542" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

542

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC542" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_a</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">metadata</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">chrom</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span> <span class="o" style="font-weight: 600;">==</span> <span class="n" style="color: #333333;">vcf_b</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">metadata</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">chrom</span><span class="sh" style="color: #dd1144;">'</span><span class="p">])</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="543" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

543

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC543" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_a</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">metadata</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">ploidy</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span> <span class="o" style="font-weight: 600;">==</span> <span class="n" style="color: #333333;">vcf_b</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">metadata</span><span class="sh" style="color: #dd1144;">'</span><span class="p">][</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">ploidy</span><span class="sh" style="color: #dd1144;">'</span><span class="p">])</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="544" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

544

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC544" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="545" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

545

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC545" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">## positions should be the same (positions are only reflective of data in `sequences`, so the ignoring of insertions is ok)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="546" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

546

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC546" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_a</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">positions</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span><span class="o" style="font-weight: 600;">==</span><span class="n" style="color: #333333;">vcf_a</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">positions</span><span class="sh" style="color: #dd1144;">'</span><span class="p">])</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="547" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

547

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC547" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">## check sequences are the same</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="0" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="548" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

548

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC548" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">assert</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_a</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span><span class="o" style="font-weight: 600;">==</span><span class="n" style="color: #333333;">vcf_b</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">])</span></span></pre></td>

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<br>

</li>

<li id="69dc641dc8a4f2ceee2025d190e2e761dcae3c84">

<a href="https://salsa.debian.org/med-team/python-treetime/-/commit/e6064017dcfbf63072b9d8a06cc5775d5eff2f6e#69dc641dc8a4f2ceee2025d190e2e761dcae3c84"><strong style="font-weight: 600;">treetime/CLI_io.py</strong></a>

<hr style="overflow: hidden; border: 1px solid #e1e1e1;">

<table class="code white" style="border-spacing: 0; border-collapse: collapse; width: auto; font-family: monospace; font-size: 90%;" bgcolor="#ffffff" width="100%" cellpadding="0" cellspacing="0">

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<td class="diff-line-num unfold js-unfold old_line" data-linenumber="164" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="diff-line-num unfold js-unfold new_line" data-linenumber="164" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="line_content match" style="color: rgba(5,5,6,.24); padding: inherit;" bgcolor="#fbfafd">@@ -164,15 +164,15 @@ def export_sequences_and_tree(tt, basename, is_vcf=False, zero_based=False,</td>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC164" class="line" lang="python">                    <span class="n" style="color: #333333;">n</span><span class="p">.</span><span class="n" style="color: #333333;">comment</span><span class="o" style="font-weight: 600;">=</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">&mutations=</span><span class="sh" style="color: #dd1144;">"'</span> <span class="o" style="font-weight: 600;">+</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">,</span><span class="sh" style="color: #dd1144;">'</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">join</span><span class="p">([</span><span class="n" style="color: #333333;">a</span><span class="o" style="font-weight: 600;">+</span><span class="nf" style="color: #990000; font-weight: 600;">str</span><span class="p">(</span><span class="n" style="color: #333333;">pos</span> <span class="o" style="font-weight: 600;">+</span> <span class="n" style="color: #333333;">offset</span><span class="p">)</span><span class="o" style="font-weight: 600;">+</span><span class="n" style="color: #333333;">d</span> <span class="nf" style="color: #990000; font-weight: 600;">for </span><span class="p">(</span><span class="n" style="color: #333333;">a</span><span class="p">,</span><span class="n" style="color: #333333;">pos</span><span class="p">,</span> <span class="n" style="color: #333333;">d</span><span class="p">)</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">n</span><span class="p">.</span><span class="n" style="color: #333333;">mutations</span></span>

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165

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC165" class="line" lang="python">                                                        <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">tt</span><span class="p">.</span><span class="n" style="color: #333333;">gtr</span><span class="p">.</span><span class="n" style="color: #333333;">ambiguous</span> <span class="ow" style="font-weight: 600;">not</span> <span class="ow" style="font-weight: 600;">in</span> <span class="p">[</span><span class="n" style="color: #333333;">a</span><span class="p">,</span><span class="n" style="color: #333333;">d</span><span class="p">]</span> <span class="ow" style="font-weight: 600;">and</span> <span class="n" style="color: #333333;">n</span><span class="p">.</span><span class="n" style="color: #333333;">mask</span><span class="p">[</span><span class="n" style="color: #333333;">pos</span><span class="p">]</span><span class="o" style="font-weight: 600;">></span><span class="mi" style="color: #009999;">0</span><span class="p">])</span><span class="o" style="font-weight: 600;">+</span><span class="sa">f</span><span class="sh" style="color: #dd1144;">'"</span><span class="s" style="color: #dd1144;">,mcc=</span><span class="sh" style="color: #dd1144;">"</span><span class="si" style="color: #dd1144;">{</span><span class="n" style="color: #333333;">n</span><span class="p">.</span><span class="n" style="color: #333333;">mcc</span><span class="si" style="color: #dd1144;">}</span><span class="sh" style="color: #dd1144;">"'</span></span>

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166

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC166" class="line" lang="python"></span>

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167

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<td class="new_line diff-line-num old" data-linenumber="167" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC167" class="line" lang="python">            <span class="idiff left right deletion" style="background-color: #fac5cd;">    </span><span class="nf" style="color: #990000; font-weight: 600;">for </span><span class="p">(</span><span class="n" style="color: #333333;">a</span><span class="p">,</span> <span class="n" style="color: #333333;">pos</span><span class="p">,</span> <span class="n" style="color: #333333;">d</span><span class="p">)</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">n</span><span class="p">.</span><span class="n" style="color: #333333;">mutations</span><span class="p">:</span></span>

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168

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<td class="new_line diff-line-num old" data-linenumber="167" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC168" class="line" lang="python">                <span class="idiff left right deletion" style="background-color: #fac5cd;">    </span><span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">tt</span><span class="p">.</span><span class="n" style="color: #333333;">gtr</span><span class="p">.</span><span class="n" style="color: #333333;">ambiguous</span> <span class="ow" style="font-weight: 600;">not</span> <span class="ow" style="font-weight: 600;">in</span> <span class="p">[</span><span class="n" style="color: #333333;">a</span><span class="p">,</span><span class="n" style="color: #333333;">d</span><span class="p">]</span> <span class="ow" style="font-weight: 600;">or</span> <span class="n" style="color: #333333;">report_ambiguous</span><span class="p">:</span></span>

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169

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<td class="new_line diff-line-num old" data-linenumber="167" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC169" class="line" lang="python">                    <span class="idiff left right deletion" style="background-color: #fac5cd;">    </span><span class="n" style="color: #333333;">mutations_out</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">write</span><span class="p">(</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">%s</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">%s</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">%s</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">%s</span><span class="se" style="color: #dd1144;">\n</span><span class="sh" style="color: #dd1144;">"</span> <span class="o" style="font-weight: 600;">%</span><span class="p">(</span><span class="n" style="color: #333333;">n</span><span class="p">.</span><span class="n" style="color: #333333;">name</span><span class="p">,</span> <span class="n" style="color: #333333;">a</span><span class="p">,</span> <span class="n" style="color: #333333;">pos</span> <span class="o" style="font-weight: 600;">+</span> <span class="mi" style="color: #009999;">1</span><span class="p">,</span> <span class="n" style="color: #333333;">d</span><span class="p">))</span></span>

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167

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC167" class="line" lang="python">            <span class="nf" style="color: #990000; font-weight: 600;">for </span><span class="p">(</span><span class="n" style="color: #333333;">a</span><span class="p">,</span> <span class="n" style="color: #333333;">pos</span><span class="p">,</span> <span class="n" style="color: #333333;">d</span><span class="p">)</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">n</span><span class="p">.</span><span class="n" style="color: #333333;">mutations</span><span class="p">:</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC168" class="line" lang="python">                <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">tt</span><span class="p">.</span><span class="n" style="color: #333333;">gtr</span><span class="p">.</span><span class="n" style="color: #333333;">ambiguous</span> <span class="ow" style="font-weight: 600;">not</span> <span class="ow" style="font-weight: 600;">in</span> <span class="p">[</span><span class="n" style="color: #333333;">a</span><span class="p">,</span><span class="n" style="color: #333333;">d</span><span class="p">]</span> <span class="ow" style="font-weight: 600;">or</span> <span class="n" style="color: #333333;">report_ambiguous</span><span class="p">:</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="169" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

169

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC169" class="line" lang="python">                    <span class="n" style="color: #333333;">mutations_out</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">write</span><span class="p">(</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">%s</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">%s</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">%s</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;">%s</span><span class="se" style="color: #dd1144;">\n</span><span class="sh" style="color: #dd1144;">"</span> <span class="o" style="font-weight: 600;">%</span><span class="p">(</span><span class="n" style="color: #333333;">n</span><span class="p">.</span><span class="n" style="color: #333333;">name</span><span class="p">,</span> <span class="n" style="color: #333333;">a</span><span class="p">,</span> <span class="n" style="color: #333333;">pos</span> <span class="o" style="font-weight: 600;">+</span> <span class="mi" style="color: #009999;">1</span><span class="p">,</span> <span class="n" style="color: #333333;">d</span><span class="p">))</span></span>

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170

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170

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC170" class="line" lang="python">        <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">timetree</span><span class="p">:</span></span>

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<td class="new_line diff-line-num" data-linenumber="171" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC171" class="line" lang="python">            <span class="n" style="color: #333333;">n</span><span class="p">.</span><span class="n" style="color: #333333;">comment</span><span class="o" style="font-weight: 600;">+=</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">,</span><span class="sh" style="color: #dd1144;">'</span> <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">n</span><span class="p">.</span><span class="n" style="color: #333333;">comment</span> <span class="k" style="font-weight: 600;">else</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">&</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span> <span class="o" style="font-weight: 600;">+</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">date=%1.2f</span><span class="sh" style="color: #dd1144;">'</span><span class="o" style="font-weight: 600;">%</span><span class="n" style="color: #333333;">n</span><span class="p">.</span><span class="n" style="color: #333333;">numdate</span></span>

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172

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<td class="new_line diff-line-num" data-linenumber="172" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC172" class="line" lang="python">    <span class="n" style="color: #333333;">mutations_out</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">close</span><span class="p">()</span></span>

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<td class="new_line diff-line-num" data-linenumber="173" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC173" class="line" lang="python"></span>

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<td class="new_line diff-line-num" data-linenumber="174" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC174" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;"># write tree to file</span></span>

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<td class="old_line diff-line-num old" data-linenumber="175" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

175

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<td class="new_line diff-line-num old" data-linenumber="175" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC175" class="line" lang="python">    <span class="n" style="color: #333333;">fmt_bl</span> <span class="o" style="font-weight: 600;">=</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">%1.<span class="idiff left deletion" style="background-color: #fac5cd;">6</span>f</span><span class="sh" style="color: #dd1144;">"</span> <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">tt</span><span class="p">.</span><span class="n" style="color: #333333;">data</span><span class="p">.</span><span class="n" style="color: #333333;">full_length</span><span class="o" style="font-weight: 600;"><</span><span class="mf" style="color: #009999;">1e6</span> <span class="k" style="font-weight: 600;">else</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">%1.<span class="idiff right deletion" style="background-color: #fac5cd;">8</span>e</span><span class="sh" style="color: #dd1144;">"</span></span>

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<td class="old_line diff-line-num new" data-linenumber="176" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="175" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC175" class="line" lang="python">    <span class="n" style="color: #333333;">fmt_bl</span> <span class="o" style="font-weight: 600;">=</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">%1.<span class="idiff left addition" style="background-color: #c7f0d2;">7</span>f</span><span class="sh" style="color: #dd1144;">"</span> <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">tt</span><span class="p">.</span><span class="n" style="color: #333333;">data</span><span class="p">.</span><span class="n" style="color: #333333;">full_length</span><span class="o" style="font-weight: 600;"><</span><span class="mf" style="color: #009999;">1e6</span> <span class="k" style="font-weight: 600;">else</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">%1.<span class="idiff right addition" style="background-color: #c7f0d2;">9</span>e</span><span class="sh" style="color: #dd1144;">"</span></span>

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<td class="new_line diff-line-num" data-linenumber="176" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC176" class="line" lang="python">    <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">timetree</span><span class="p">:</span></span>

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<td class="new_line diff-line-num" data-linenumber="177" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC177" class="line" lang="python">        <span class="n" style="color: #333333;">outtree_name</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">basename</span> <span class="o" style="font-weight: 600;">+</span> <span class="sa">f</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">timetree</span><span class="si" style="color: #dd1144;">{</span><span class="n" style="color: #333333;">tree_suffix</span><span class="si" style="color: #dd1144;">}</span><span class="s" style="color: #dd1144;">.nexus</span><span class="sh" style="color: #dd1144;">'</span></span>

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<td class="new_line diff-line-num" data-linenumber="178" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC178" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">print</span><span class="p">(</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">--- saved divergence times in </span><span class="se" style="color: #dd1144;">\n\t</span><span class="s" style="color: #dd1144;"> %s</span><span class="se" style="color: #dd1144;">\n</span><span class="sh" style="color: #dd1144;">"</span><span class="o" style="font-weight: 600;">%</span><span class="n" style="color: #333333;">dates_fname</span><span class="p">)</span></span>

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</li>

<li id="716e6f6c16580800d13452615e2c01668aacc288">

<a href="https://salsa.debian.org/med-team/python-treetime/-/commit/e6064017dcfbf63072b9d8a06cc5775d5eff2f6e#716e6f6c16580800d13452615e2c01668aacc288"><strong style="font-weight: 600;">treetime/__init__.py</strong></a>

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1

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC1" class="line" lang="python"><span class="n" style="color: #333333;">version</span><span class="o" style="font-weight: 600;">=</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0.11.<span class="idiff left right deletion" style="background-color: #fac5cd;">1</span></span><span class="sh" style="color: #dd1144;">"</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC1" class="line" lang="python"><span class="n" style="color: #333333;">version</span><span class="o" style="font-weight: 600;">=</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">0.11.<span class="idiff left right addition" style="background-color: #c7f0d2;">4</span></span><span class="sh" style="color: #dd1144;">"</span></span>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC2" class="line" lang="python"><span class="c1" style="color: #999988; font-style: italic;">## Here we define an error class for TreeTime errors, MissingData, UnknownMethod and NotReady errors</span></span>

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3

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<td class="new_line diff-line-num" data-linenumber="3" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

3

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC3" class="line" lang="python"><span class="c1" style="color: #999988; font-style: italic;">## are all due to incorrect calling of TreeTime functions or input data that does not fit our base assumptions.</span></span>

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<td class="new_line diff-line-num" data-linenumber="4" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

4

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC4" class="line" lang="python"><span class="c1" style="color: #999988; font-style: italic;">## Errors marked as TreeTimeUnknownErrors might be due to data not fulfilling base assumptions or due</span></span>

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<br>

</li>

<li id="595202a65707f2c13afa5a4958366d4eb8a9353e">

<a href="https://salsa.debian.org/med-team/python-treetime/-/commit/e6064017dcfbf63072b9d8a06cc5775d5eff2f6e#595202a65707f2c13afa5a4958366d4eb8a9353e"><strong style="font-weight: 600;">treetime/argument_parser.py</strong></a>

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<td class="line_content match" style="color: rgba(5,5,6,.24); padding: inherit;" bgcolor="#fbfafd">@@ -81,7 +81,8 @@ tree_description = "Name of file containing the tree in newick, nexus, or phylip</td>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC81" class="line" lang="python"></span>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC82" class="line" lang="python"><span class="n" style="color: #333333;">aln_description</span> <span class="o" style="font-weight: 600;">=</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">alignment file (fasta)</span><span class="sh" style="color: #dd1144;">"</span></span>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC83" class="line" lang="python"></span>

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<td class="old_line diff-line-num old" data-linenumber="84" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="new_line diff-line-num old" data-linenumber="84" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC84" class="line" lang="python"><span class="n" style="color: #333333;">dates_description</span> <span class="o" style="font-weight: 600;">=</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">csv file with dates for nodes with </span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">node_name, date</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;"> where date is float (as in 2012.15)</span><span class="sh" style="color: #dd1144;">"</span></span>

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<td class="old_line diff-line-num new" data-linenumber="85" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="84" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC84" class="line" lang="python"><span class="n" style="color: #333333;">dates_description</span> <span class="o" style="font-weight: 600;">=</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">csv file with dates for nodes with </span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">node_name, date</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;"> where date is float (as in 2012.15) or in ISO-format (YYYY-MM-DD). </span><span class="sh" style="color: #dd1144;">"</span>\</span>

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<td class="old_line diff-line-num new" data-linenumber="85" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="85" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC85" class="line" lang="python">                    <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">Imprecisely known dates can be specified as </span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">2023-XX-XX</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;"> or [2013.2:2013.7]</span><span class="sh" style="color: #dd1144;">"</span></span>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC86" class="line" lang="python"></span>

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<td class="new_line diff-line-num" data-linenumber="87" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC87" class="line" lang="python"><span class="n" style="color: #333333;">coalescent_description</span> <span class="o" style="font-weight: 600;">=</span> \</span>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC88" class="line" lang="python">    <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">coalescent time scale -- sensible values are on the order of the average </span><span class="sh" style="color: #dd1144;">"</span>\</span>

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<td class="line_content match" style="color: rgba(5,5,6,.24); padding: inherit;" bgcolor="#fbfafd">@@ -303,6 +304,8 @@ def make_parser():</td>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC304" class="line" lang="python">    <span class="nf" style="color: #990000; font-weight: 600;">add_seq_len_aln_group</span><span class="p">(</span><span class="n" style="color: #333333;">c_parser</span><span class="p">)</span></span>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC305" class="line" lang="python"></span>

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<td class="new_line diff-line-num" data-linenumber="306" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC306" class="line" lang="python">    <span class="nf" style="color: #990000; font-weight: 600;">add_reroot_group</span><span class="p">(</span><span class="n" style="color: #333333;">c_parser</span><span class="p">)</span></span>

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<td class="old_line diff-line-num new" data-linenumber="306" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="307" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC307" class="line" lang="python">    <span class="n" style="color: #333333;">c_parser</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">add_argument</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">--prune-outliers</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="n" style="color: #333333;">action</span><span class="o" style="font-weight: 600;">=</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">store_true</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="n" style="color: #333333;">default</span><span class="o" style="font-weight: 600;">=</span><span class="bp" style="color: #999999;">False</span><span class="p">,</span></span>

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<td class="old_line diff-line-num new" data-linenumber="306" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="308" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC308" class="line" lang="python">                        <span class="n" style="color: #333333;">help</span><span class="o" style="font-weight: 600;">=</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">remove detected outliers from the output tree</span><span class="sh" style="color: #dd1144;">"</span><span class="p">)</span></span>

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<td class="new_line diff-line-num" data-linenumber="309" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC309" class="line" lang="python">    <span class="n" style="color: #333333;">c_parser</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">add_argument</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">--allow-negative-rate</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="n" style="color: #333333;">required</span> <span class="o" style="font-weight: 600;">=</span> <span class="bp" style="color: #999999;">False</span><span class="p">,</span> <span class="n" style="color: #333333;">action</span><span class="o" style="font-weight: 600;">=</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">store_true</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="n" style="color: #333333;">default</span><span class="o" style="font-weight: 600;">=</span><span class="bp" style="color: #999999;">False</span><span class="p">,</span></span>

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<td class="new_line diff-line-num" data-linenumber="310" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC310" class="line" lang="python">                          <span class="n" style="color: #333333;">help</span><span class="o" style="font-weight: 600;">=</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">By default, rates are forced to be positive. For trees with little temporal </span><span class="sh" style="color: #dd1144;">"</span></span>

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<td class="old_line diff-line-num" data-linenumber="308" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="new_line diff-line-num" data-linenumber="311" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC311" class="line" lang="python">                               <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">signal it is advisable to remove this restriction to achieve essentially mid-point rooting.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">)</span></span>

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<br>

</li>

<li id="b990c4f689cacd4a1e8800b187c4078a5c5ed01f">

<a href="https://salsa.debian.org/med-team/python-treetime/-/commit/e6064017dcfbf63072b9d8a06cc5775d5eff2f6e#b990c4f689cacd4a1e8800b187c4078a5c5ed01f"><strong style="font-weight: 600;">treetime/gtr.py</strong></a>

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<td class="line_content match" style="color: rgba(5,5,6,.24); padding: inherit;" bgcolor="#fbfafd">@@ -476,8 +476,8 @@ class GTR(object):</td>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC476" class="line" lang="python">        <span class="n" style="color: #333333;">alphabet</span><span class="o" style="font-weight: 600;">=</span><span class="n" style="color: #333333;">alphabets</span><span class="p">[</span><span class="n" style="color: #333333;">alphabet</span><span class="p">]</span></span>

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<td class="new_line diff-line-num" data-linenumber="477" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC477" class="line" lang="python">        <span class="n" style="color: #333333;">gtr</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">cls</span><span class="p">(</span><span class="n" style="color: #333333;">alphabet</span><span class="p">)</span></span>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC478" class="line" lang="python">        <span class="n" style="color: #333333;">n</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">gtr</span><span class="p">.</span><span class="n" style="color: #333333;">alphabet</span><span class="p">.</span><span class="n" style="color: #333333;">shape</span><span class="p">[</span><span class="mi" style="color: #009999;">0</span><span class="p">]</span></span>

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<td class="new_line diff-line-num old" data-linenumber="479" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC479" class="line" lang="python">        <span class="n" style="color: #333333;">pi</span> <span class="o" style="font-weight: 600;">=</span> <span class="mf" style="color: #009999;">1.0</span><span class="o" style="font-weight: 600;">*</span><span class="n" style="color: #333333;">rng</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">rand<span class="idiff left deletion" style="background-color: #fac5cd;">int</span></span><span class="p"><span class="idiff deletion" style="background-color: #fac5cd;">(</span></span><span class="mi" style="color: #009999;"><span class="idiff deletion" style="background-color: #fac5cd;">0</span></span><span class="p"><span class="idiff deletion" style="background-color: #fac5cd;">,</span></span><span class="mi" style="color: #009999;"><span class="idiff deletion" style="background-color: #fac5cd;">100</span></span><span class="p"><span class="idiff deletion" style="background-color: #fac5cd;">,</span></span><span class="n" style="color: #333333;">size</span><span class="o" style="font-weight: 600;">=</span><span class="p"><span class="idiff deletion" style="background-color: #fac5cd;">(</span></span><span class="n" style="color: #333333;">n</span><span class="p">)<span class="idiff right deletion" style="background-color: #fac5cd;">)</span></span></span>

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<td class="new_line diff-line-num old" data-linenumber="479" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC480" class="line" lang="python">        <span class="n" style="color: #333333;">W</span> <span class="o" style="font-weight: 600;">=</span> <span class="mf" style="color: #009999;">1.0</span><span class="o" style="font-weight: 600;">*</span><span class="n" style="color: #333333;">rng</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">rand<span class="idiff left deletion" style="background-color: #fac5cd;">int</span></span><span class="p"><span class="idiff deletion" style="background-color: #fac5cd;">(</span></span><span class="mi" style="color: #009999;"><span class="idiff deletion" style="background-color: #fac5cd;">0</span></span><span class="p"><span class="idiff deletion" style="background-color: #fac5cd;">,</span></span><span class="mi" style="color: #009999;"><span class="idiff deletion" style="background-color: #fac5cd;">100</span></span><span class="p"><span class="idiff right deletion" style="background-color: #fac5cd;">,</span></span><span class="n" style="color: #333333;">size</span><span class="o" style="font-weight: 600;">=</span><span class="p">(</span><span class="n" style="color: #333333;">n</span><span class="p">,</span><span class="n" style="color: #333333;">n</span><span class="p">))</span> <span class="c1" style="color: #999988; font-style: italic;"># with gaps</span></span>

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<td class="old_line diff-line-num new" data-linenumber="481" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="479" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

479

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC479" class="line" lang="python">        <span class="n" style="color: #333333;">pi</span> <span class="o" style="font-weight: 600;">=</span> <span class="mf" style="color: #009999;">1.0</span><span class="o" style="font-weight: 600;">*</span><span class="n" style="color: #333333;">rng</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">rand<span class="idiff left addition" style="background-color: #c7f0d2;">om</span></span><span class="p"><span class="idiff right addition" style="background-color: #c7f0d2;">(</span></span><span class="n" style="color: #333333;">size</span><span class="o" style="font-weight: 600;">=</span><span class="n" style="color: #333333;">n</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="481" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="480" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

480

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC480" class="line" lang="python">        <span class="n" style="color: #333333;">W</span> <span class="o" style="font-weight: 600;">=</span> <span class="mf" style="color: #009999;">1.0</span><span class="o" style="font-weight: 600;">*</span><span class="n" style="color: #333333;">rng</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">rand<span class="idiff left addition" style="background-color: #c7f0d2;">om</span></span><span class="p"><span class="idiff right addition" style="background-color: #c7f0d2;">(</span></span><span class="n" style="color: #333333;">size</span><span class="o" style="font-weight: 600;">=</span><span class="p">(</span><span class="n" style="color: #333333;">n</span><span class="p">,</span><span class="n" style="color: #333333;">n</span><span class="p">))</span> <span class="c1" style="color: #999988; font-style: italic;"># with gaps</span></span>

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<td class="old_line diff-line-num" data-linenumber="481" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

481

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<td class="new_line diff-line-num" data-linenumber="481" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

481

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC481" class="line" lang="python"></span>

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<td class="old_line diff-line-num" data-linenumber="482" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

482

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<td class="new_line diff-line-num" data-linenumber="482" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

482

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC482" class="line" lang="python">        <span class="n" style="color: #333333;">gtr</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">assign_rates</span><span class="p">(</span><span class="n" style="color: #333333;">mu</span><span class="o" style="font-weight: 600;">=</span><span class="n" style="color: #333333;">mu</span><span class="p">,</span> <span class="n" style="color: #333333;">pi</span><span class="o" style="font-weight: 600;">=</span><span class="n" style="color: #333333;">pi</span><span class="p">,</span> <span class="n" style="color: #333333;">W</span><span class="o" style="font-weight: 600;">=</span><span class="n" style="color: #333333;">W</span><span class="p">)</span></span>

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<td class="old_line diff-line-num" data-linenumber="483" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

483

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<td class="new_line diff-line-num" data-linenumber="483" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

483

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC483" class="line" lang="python">        <span class="k" style="font-weight: 600;">return</span> <span class="n" style="color: #333333;">gtr</span></span>

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<td class="diff-line-num unfold js-unfold old_line" data-linenumber="851" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="diff-line-num unfold js-unfold new_line" data-linenumber="851" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="line_content match" style="color: rgba(5,5,6,.24); padding: inherit;" bgcolor="#fbfafd">@@ -851,7 +851,11 @@ class GTR(object):</td>

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<td class="old_line diff-line-num" data-linenumber="851" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

851

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<td class="new_line diff-line-num" data-linenumber="851" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

851

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC851" class="line" lang="python">            <span class="k" style="font-weight: 600;">else</span><span class="p">:</span></span>

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<td class="old_line diff-line-num" data-linenumber="852" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

852

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<td class="new_line diff-line-num" data-linenumber="852" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

852

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC852" class="line" lang="python">                <span class="k" style="font-weight: 600;">return</span> <span class="o" style="font-weight: 600;">-</span><span class="mf" style="color: #009999;">1.0</span><span class="o" style="font-weight: 600;">*</span><span class="n" style="color: #333333;">self</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">prob_t_compressed</span><span class="p">(</span><span class="n" style="color: #333333;">seq_pair</span><span class="p">,</span> <span class="n" style="color: #333333;">multiplicity</span><span class="p">,</span><span class="n" style="color: #333333;">t</span><span class="o" style="font-weight: 600;">**</span><span class="mi" style="color: #009999;">2</span><span class="p">,</span> <span class="n" style="color: #333333;">return_log</span><span class="o" style="font-weight: 600;">=</span><span class="bp" style="color: #999999;">True</span><span class="p">)</span></span>

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<td class="old_line diff-line-num" data-linenumber="853" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

853

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<td class="new_line diff-line-num" data-linenumber="853" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

853

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC853" class="line" lang="python"></span>

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<td class="old_line diff-line-num old" data-linenumber="854" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

854

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<td class="new_line diff-line-num old" data-linenumber="854" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC854" class="line" lang="python">        <span class="n" style="color: #333333;">hamming_distance</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">np</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">sum</span><span class="p">(</span><span class="n" style="color: #333333;">multiplicity</span><span class="p">[</span><span class="n" style="color: #333333;">seq_pair</span><span class="p">[:,</span><span class="mi" style="color: #009999;">1</span><span class="p">]</span><span class="o" style="font-weight: 600;">!=</span><span class="n" style="color: #333333;">seq_pair</span><span class="p">[:,</span><span class="mi" style="color: #009999;">0</span><span class="p">]])</span><span class="o" style="font-weight: 600;">/</span><span class="n" style="color: #333333;">np</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">sum</span><span class="p">(</span><span class="n" style="color: #333333;">multiplicity</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="855" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="854" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

854

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC854" class="line" lang="python">        <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">profiles</span><span class="p">:</span></span>

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855

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC855" class="line" lang="python">            <span class="n" style="color: #333333;">hamming_distance</span> <span class="o" style="font-weight: 600;">=</span> <span class="mi" style="color: #009999;">1</span><span class="o" style="font-weight: 600;">-</span><span class="n" style="color: #333333;">np</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">sum</span><span class="p">(</span><span class="n" style="color: #333333;">multiplicity</span><span class="o" style="font-weight: 600;">*</span><span class="n" style="color: #333333;">np</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">sum</span><span class="p">(</span><span class="n" style="color: #333333;">seq_pair</span><span class="p">[</span><span class="mi" style="color: #009999;">0</span><span class="p">]</span><span class="o" style="font-weight: 600;">*</span><span class="n" style="color: #333333;">seq_pair</span><span class="p">[</span><span class="mi" style="color: #009999;">1</span><span class="p">],</span> <span class="n" style="color: #333333;">axis</span><span class="o" style="font-weight: 600;">=</span><span class="mi" style="color: #009999;">1</span><span class="p">))</span><span class="o" style="font-weight: 600;">/</span><span class="n" style="color: #333333;">np</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">sum</span><span class="p">(</span><span class="n" style="color: #333333;">multiplicity</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="855" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="856" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

856

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC856" class="line" lang="python">        <span class="k" style="font-weight: 600;">else</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="855" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="857" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

857

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC857" class="line" lang="python">            <span class="n" style="color: #333333;">hamming_distance</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">np</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">sum</span><span class="p">(</span><span class="n" style="color: #333333;">multiplicity</span><span class="p">[</span><span class="n" style="color: #333333;">seq_pair</span><span class="p">[:,</span><span class="mi" style="color: #009999;">1</span><span class="p">]</span><span class="o" style="font-weight: 600;">!=</span><span class="n" style="color: #333333;">seq_pair</span><span class="p">[:,</span><span class="mi" style="color: #009999;">0</span><span class="p">]])</span><span class="o" style="font-weight: 600;">/</span><span class="n" style="color: #333333;">np</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">sum</span><span class="p">(</span><span class="n" style="color: #333333;">multiplicity</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="855" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="858" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

858

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC858" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="855" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

855

</td>

<td class="new_line diff-line-num" data-linenumber="859" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

859

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC859" class="line" lang="python">        <span class="k" style="font-weight: 600;">try</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="856" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

856

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<td class="new_line diff-line-num" data-linenumber="860" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

860

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC860" class="line" lang="python">            <span class="kn" style="font-weight: 600;">from</span> <span class="n" style="color: #333333;">scipy.optimize</span> <span class="kn" style="font-weight: 600;">import</span> <span class="n" style="color: #333333;">minimize_scalar</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="857" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

857

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<td class="new_line diff-line-num" data-linenumber="861" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

861

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC861" class="line" lang="python">            <span class="n" style="color: #333333;">opt</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">minimize_scalar</span><span class="p">(</span><span class="n" style="color: #333333;">_neg_prob</span><span class="p">,</span></span>

</pre></td>

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<br>

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<li id="a2e471fd9fc09543e8fd92727442680e1b76576b">

<a href="https://salsa.debian.org/med-team/python-treetime/-/commit/e6064017dcfbf63072b9d8a06cc5775d5eff2f6e#a2e471fd9fc09543e8fd92727442680e1b76576b"><strong style="font-weight: 600;">treetime/treeanc.py</strong></a>

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<table class="code white" style="border-spacing: 0; border-collapse: collapse; width: auto; font-family: monospace; font-size: 90%;" bgcolor="#ffffff" width="100%" cellpadding="0" cellspacing="0">

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<td class="diff-line-num unfold js-unfold old_line" data-linenumber="572" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="diff-line-num unfold js-unfold new_line" data-linenumber="572" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="line_content match" style="color: rgba(5,5,6,.24); padding: inherit;" bgcolor="#fbfafd">@@ -572,7 +572,7 @@ class TreeAnc(object):</td>

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572

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<td class="new_line diff-line-num" data-linenumber="572" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

572

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC572" class="line" lang="python">                                    <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">in the position %d: %s, </span><span class="sh" style="color: #dd1144;">"</span></span>

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<td class="old_line diff-line-num" data-linenumber="573" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

573

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<td class="new_line diff-line-num" data-linenumber="573" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

573

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC573" class="line" lang="python">                                    <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">choosing %s</span><span class="sh" style="color: #dd1144;">"</span> <span class="o" style="font-weight: 600;">%</span> <span class="p">(</span><span class="n" style="color: #333333;">amb</span><span class="p">,</span> <span class="nf" style="color: #990000; font-weight: 600;">str</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">.</span><span class="n" style="color: #333333;">tree</span><span class="p">.</span><span class="n" style="color: #333333;">root</span><span class="p">.</span><span class="n" style="color: #333333;">state</span><span class="p">[</span><span class="n" style="color: #333333;">amb</span><span class="p">]),</span></span>

</pre></td>

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574

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<td class="new_line diff-line-num" data-linenumber="574" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

574

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC574" class="line" lang="python">                                                     <span class="n" style="color: #333333;">self</span><span class="p">.</span><span class="n" style="color: #333333;">tree</span><span class="p">.</span><span class="n" style="color: #333333;">root</span><span class="p">.</span><span class="n" style="color: #333333;">state</span><span class="p">[</span><span class="n" style="color: #333333;">amb</span><span class="p">][</span><span class="mi" style="color: #009999;">0</span><span class="p">]),</span> <span class="mi" style="color: #009999;">4</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="575" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

575

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<td class="new_line diff-line-num old" data-linenumber="575" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC575" class="line" lang="python">        <span class="n" style="color: #333333;">self</span><span class="p">.</span><span class="n" style="color: #333333;">tree</span><span class="p">.</span><span class="n" style="color: #333333;">root</span><span class="p">.</span><span class="n" style="color: #333333;">_cseq</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">np</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">array</span><span class="p">([</span><span class="n" style="color: #333333;">k</span><span class="p">[</span><span class="n" style="color: #333333;">self</span><span class="p">.</span><span class="n" style="color: #333333;">rng</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;"><span class="idiff left right deletion" style="background-color: #fac5cd;">randint</span></span><span class="p">(</span><span class="nf" style="color: #990000; font-weight: 600;">len</span><span class="p">(</span><span class="n" style="color: #333333;">k</span><span class="p">))</span> <span class="k" style="font-weight: 600;">if</span> <span class="nf" style="color: #990000; font-weight: 600;">len</span><span class="p">(</span><span class="n" style="color: #333333;">k</span><span class="p">)</span><span class="o" style="font-weight: 600;">></span><span class="mi" style="color: #009999;">1</span> <span class="k" style="font-weight: 600;">else</span> <span class="mi" style="color: #009999;">0</span><span class="p">]</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC575" class="line" lang="python">        <span class="n" style="color: #333333;">self</span><span class="p">.</span><span class="n" style="color: #333333;">tree</span><span class="p">.</span><span class="n" style="color: #333333;">root</span><span class="p">.</span><span class="n" style="color: #333333;">_cseq</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">np</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">array</span><span class="p">([</span><span class="n" style="color: #333333;">k</span><span class="p">[</span><span class="n" style="color: #333333;">self</span><span class="p">.</span><span class="n" style="color: #333333;">rng</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;"><span class="idiff left right addition" style="background-color: #c7f0d2;">integers</span></span><span class="p">(</span><span class="nf" style="color: #990000; font-weight: 600;">len</span><span class="p">(</span><span class="n" style="color: #333333;">k</span><span class="p">))</span> <span class="k" style="font-weight: 600;">if</span> <span class="nf" style="color: #990000; font-weight: 600;">len</span><span class="p">(</span><span class="n" style="color: #333333;">k</span><span class="p">)</span><span class="o" style="font-weight: 600;">></span><span class="mi" style="color: #009999;">1</span> <span class="k" style="font-weight: 600;">else</span> <span class="mi" style="color: #009999;">0</span><span class="p">]</span></span>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC576" class="line" lang="python">                                           <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">k</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">self</span><span class="p">.</span><span class="n" style="color: #333333;">tree</span><span class="p">.</span><span class="n" style="color: #333333;">root</span><span class="p">.</span><span class="n" style="color: #333333;">state</span><span class="p">])</span></span>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC577" class="line" lang="python"></span>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC578" class="line" lang="python"></span>

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<td class="diff-line-num unfold js-unfold old_line" data-linenumber="1670" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

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<td class="line_content match" style="color: rgba(5,5,6,.24); padding: inherit;" bgcolor="#fbfafd">@@ -1670,7 +1670,7 @@ class TreeAnc(object):</td>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC1670" class="line" lang="python"></span>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC1671" class="line" lang="python"></span>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC1672" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">get_tree_dict</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">keep_var_ambigs</span><span class="o" style="font-weight: 600;">=</span><span class="bp" style="color: #999999;">False</span><span class="p">):</span></span>

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<td class="old_line diff-line-num old" data-linenumber="1673" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="new_line diff-line-num old" data-linenumber="1673" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC1673" class="line" lang="python">        <span class="k" style="font-weight: 600;">return</span> <span class="n" style="color: #333333;">self</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">get_reconstructed_alignment</span><span class="p">()</span></span>

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<td class="old_line diff-line-num new" data-linenumber="1674" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="1673" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC1673" class="line" lang="python">        <span class="k" style="font-weight: 600;">return</span> <span class="n" style="color: #333333;">self</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">get_reconstructed_alignment</span><span class="p">(</span><span class="n" style="color: #333333;"><span class="idiff left addition" style="background-color: #c7f0d2;">reconstruct_tip_states</span></span><span class="o" style="font-weight: 600;"><span class="idiff addition" style="background-color: #c7f0d2;">=</span></span><span class="ow" style="font-weight: 600;"><span class="idiff addition" style="background-color: #c7f0d2;">not</span></span><span class="idiff addition" style="background-color: #c7f0d2;"> </span><span class="n" style="color: #333333;"><span class="idiff right addition" style="background-color: #c7f0d2;">keep_var_ambigs</span></span><span class="p">)</span></span>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC1675" class="line" lang="python"></span>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC1676" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">recover_var_ambigs</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">):</span></span>

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<li id="0994bbb65b28bed19201420b96136d5e9f676859">

<a href="https://salsa.debian.org/med-team/python-treetime/-/commit/e6064017dcfbf63072b9d8a06cc5775d5eff2f6e#0994bbb65b28bed19201420b96136d5e9f676859"><strong style="font-weight: 600;">treetime/treetime.py</strong></a>

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<td class="line_content match" style="color: rgba(5,5,6,.24); padding: inherit;" bgcolor="#fbfafd">@@ -73,7 +73,7 @@ class TreeTime(ClockTree):</td>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC73" class="line" lang="python">                <span class="n" style="color: #333333;">sys</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">exit</span><span class="p">(</span><span class="mi" style="color: #009999;">2</span><span class="p">)</span></span>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC74" class="line" lang="python"></span>

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<td class="old_line diff-line-num" data-linenumber="75" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

75

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<td class="new_line diff-line-num" data-linenumber="75" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC75" class="line" lang="python"></span>

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<td class="old_line diff-line-num old" data-linenumber="76" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="new_line diff-line-num old" data-linenumber="76" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC76" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">_run</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">root</span><span class="o" style="font-weight: 600;">=</span><span class="bp" style="color: #999999;">None</span><span class="p">,</span> <span class="n" style="color: #333333;">infer_gtr</span><span class="o" style="font-weight: 600;">=</span><span class="bp" style="color: #999999;">True</span><span class="p">,</span> <span class="n" style="color: #333333;">relaxed_clock</span><span class="o" style="font-weight: 600;">=</span><span class="bp" style="color: #999999;">None</span><span class="p">,</span> <span class="n" style="color: #333333;">clock_filter_method</span><span class="o" style="font-weight: 600;">=</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">residual<span class="idiff left right deletion" style="background-color: #fac5cd;">s</span></span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span></span>

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<td class="old_line diff-line-num new" data-linenumber="77" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="76" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC76" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">_run</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">root</span><span class="o" style="font-weight: 600;">=</span><span class="bp" style="color: #999999;">None</span><span class="p">,</span> <span class="n" style="color: #333333;">infer_gtr</span><span class="o" style="font-weight: 600;">=</span><span class="bp" style="color: #999999;">True</span><span class="p">,</span> <span class="n" style="color: #333333;">relaxed_clock</span><span class="o" style="font-weight: 600;">=</span><span class="bp" style="color: #999999;">None</span><span class="p">,</span> <span class="n" style="color: #333333;">clock_filter_method</span><span class="o" style="font-weight: 600;">=</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">residual</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span></span>

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<td class="old_line diff-line-num" data-linenumber="77" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="new_line diff-line-num" data-linenumber="77" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC77" class="line" lang="python">             <span class="n" style="color: #333333;">n_iqd</span> <span class="o" style="font-weight: 600;">=</span> <span class="bp" style="color: #999999;">None</span><span class="p">,</span> <span class="n" style="color: #333333;">resolve_polytomies</span><span class="o" style="font-weight: 600;">=</span><span class="bp" style="color: #999999;">True</span><span class="p">,</span> <span class="n" style="color: #333333;">max_iter</span><span class="o" style="font-weight: 600;">=</span><span class="mi" style="color: #009999;">0</span><span class="p">,</span> <span class="n" style="color: #333333;">Tc</span><span class="o" style="font-weight: 600;">=</span><span class="bp" style="color: #999999;">None</span><span class="p">,</span> <span class="n" style="color: #333333;">fixed_clock_rate</span><span class="o" style="font-weight: 600;">=</span><span class="bp" style="color: #999999;">None</span><span class="p">,</span></span>

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<td class="old_line diff-line-num" data-linenumber="78" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

78

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<td class="new_line diff-line-num" data-linenumber="78" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC78" class="line" lang="python">            <span class="n" style="color: #333333;">time_marginal</span><span class="o" style="font-weight: 600;">=</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">never</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="n" style="color: #333333;">sequence_marginal</span><span class="o" style="font-weight: 600;">=</span><span class="bp" style="color: #999999;">False</span><span class="p">,</span> <span class="n" style="color: #333333;">branch_length_mode</span><span class="o" style="font-weight: 600;">=</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">auto</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span></span>

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<td class="old_line diff-line-num" data-linenumber="79" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="new_line diff-line-num" data-linenumber="79" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC79" class="line" lang="python">            <span class="n" style="color: #333333;">vary_rate</span><span class="o" style="font-weight: 600;">=</span><span class="bp" style="color: #999999;">False</span><span class="p">,</span> <span class="n" style="color: #333333;">use_covariation</span><span class="o" style="font-weight: 600;">=</span><span class="bp" style="color: #999999;">False</span><span class="p">,</span> <span class="n" style="color: #333333;">tracelog_file</span><span class="o" style="font-weight: 600;">=</span><span class="bp" style="color: #999999;">None</span><span class="p">,</span></span>

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<td class="diff-line-num unfold js-unfold old_line" data-linenumber="423" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="diff-line-num unfold js-unfold new_line" data-linenumber="423" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="line_content match" style="color: rgba(5,5,6,.24); padding: inherit;" bgcolor="#fbfafd">@@ -423,6 +423,8 @@ class TreeTime(ClockTree):</td>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC423" class="line" lang="python">            <span class="n" style="color: #333333;">bad_branch_count</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">residual_filter</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">n_iqd</span><span class="p">)</span></span>

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<td class="new_line diff-line-num" data-linenumber="424" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC424" class="line" lang="python">        <span class="k" style="font-weight: 600;">elif</span> <span class="n" style="color: #333333;">method</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">local</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span></span>

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<td class="new_line diff-line-num" data-linenumber="425" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC425" class="line" lang="python">            <span class="n" style="color: #333333;">bad_branch_count</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">local_filter</span><span class="p">(</span><span class="n" style="color: #333333;">self</span><span class="p">,</span> <span class="n" style="color: #333333;">n_iqd</span><span class="p">)</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC426" class="line" lang="python">        <span class="k" style="font-weight: 600;">else</span><span class="p">:</span></span>

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<td class="old_line diff-line-num new" data-linenumber="426" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="427" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

427

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC427" class="line" lang="python">            <span class="k" style="font-weight: 600;">raise</span> <span class="nc" style="color: #445588; font-weight: 600;">ValueError</span><span class="p">(</span><span class="sa">f</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">TreeTime.clock_filter: unknown clock-filter method </span><span class="sh" style="color: #dd1144;">'</span><span class="si" style="color: #dd1144;">{</span><span class="n" style="color: #333333;">method</span><span class="si" style="color: #dd1144;">}</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">. Implemented methods are: </span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">residual</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">, </span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">local</span><span class="sh" style="color: #dd1144;">'"</span><span class="p">)</span></span>

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426

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<td class="new_line diff-line-num" data-linenumber="428" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

428

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC428" class="line" lang="python"></span>

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<td class="old_line diff-line-num" data-linenumber="427" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

427

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<td class="new_line diff-line-num" data-linenumber="429" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

429

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC429" class="line" lang="python">        <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">bad_branch_count</span><span class="o" style="font-weight: 600;">></span><span class="mf" style="color: #009999;">0.34</span><span class="o" style="font-weight: 600;">*</span><span class="n" style="color: #333333;">self</span><span class="p">.</span><span class="n" style="color: #333333;">tree</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">count_terminals</span><span class="p">():</span></span>

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<td class="old_line diff-line-num" data-linenumber="428" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

428

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<td class="new_line diff-line-num" data-linenumber="430" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

430

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC430" class="line" lang="python">            <span class="n" style="color: #333333;">self</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">logger</span><span class="p">(</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">TreeTime.clock_filter: More than a third of leaves have been excluded by the clock filter. Please check your input data.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="mi" style="color: #009999;">0</span><span class="p">,</span> <span class="n" style="color: #333333;">warn</span><span class="o" style="font-weight: 600;">=</span><span class="bp" style="color: #999999;">True</span><span class="p">)</span></span>

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<br>

</li>

<li id="86f02b8df99e58795d36ed9e703173e372da3411">

<a href="https://salsa.debian.org/med-team/python-treetime/-/commit/e6064017dcfbf63072b9d8a06cc5775d5eff2f6e#86f02b8df99e58795d36ed9e703173e372da3411"><strong style="font-weight: 600;">treetime/vcf_utils.py</strong></a>

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<td class="diff-line-num unfold js-unfold old_line" data-linenumber="2" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="diff-line-num unfold js-unfold new_line" data-linenumber="2" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="line_content match" style="color: rgba(5,5,6,.24); padding: inherit;" bgcolor="#fbfafd">@@ -2,6 +2,7 @@ import gzip</td>

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2

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<td class="new_line diff-line-num" data-linenumber="2" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

2

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC2" class="line" lang="python"><span class="kn" style="font-weight: 600;">import</span> <span class="n" style="color: #333333;">numpy</span> <span class="k" style="font-weight: 600;">as</span> <span class="n" style="color: #333333;">np</span></span>

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<td class="old_line diff-line-num" data-linenumber="3" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

3

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<td class="new_line diff-line-num" data-linenumber="3" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

3

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC3" class="line" lang="python"><span class="kn" style="font-weight: 600;">from</span> <span class="n" style="color: #333333;">collections</span> <span class="kn" style="font-weight: 600;">import</span> <span class="n" style="color: #333333;">defaultdict</span></span>

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<td class="old_line diff-line-num" data-linenumber="4" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

4

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<td class="new_line diff-line-num" data-linenumber="4" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

4

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC4" class="line" lang="python"><span class="kn" style="font-weight: 600;">from</span> <span class="n" style="color: #333333;">textwrap</span> <span class="kn" style="font-weight: 600;">import</span> <span class="n" style="color: #333333;">fill</span></span>

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<td class="old_line diff-line-num new" data-linenumber="5" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="5" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

5

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC5" class="line" lang="python"><span class="kn" style="font-weight: 600;">from</span> <span class="n" style="color: #333333;">.</span> <span class="kn" style="font-weight: 600;">import</span> <span class="n" style="color: #333333;">TreeTimeError</span></span>

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<td class="old_line diff-line-num" data-linenumber="5" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

5

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<td class="new_line diff-line-num" data-linenumber="6" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

6

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC6" class="line" lang="python"></span>

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<td class="old_line diff-line-num" data-linenumber="6" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

6

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<td class="new_line diff-line-num" data-linenumber="7" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

7

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC7" class="line" lang="python"><span class="c1" style="color: #999988; font-style: italic;">## Functions to read in and print out VCF files</span></span>

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<td class="old_line diff-line-num" data-linenumber="7" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

7

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<td class="new_line diff-line-num" data-linenumber="8" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

8

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC8" class="line" lang="python"></span>

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<td class="diff-line-num unfold js-unfold old_line" data-linenumber="54" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="diff-line-num unfold js-unfold new_line" data-linenumber="55" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="line_content match" style="color: rgba(5,5,6,.24); padding: inherit;" bgcolor="#fbfafd">@@ -54,6 +55,8 @@ def read_vcf(vcf_file, ref_file=None):</td>

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<td class="new_line diff-line-num" data-linenumber="55" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC55" class="line" lang="python"><span class="s" style="color: #dd1144;">            Python list of all positions with a mutation, insertion, or deletion.</span></span>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC56" class="line" lang="python"></span>

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<td class="new_line diff-line-num" data-linenumber="57" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC57" class="line" lang="python"><span class="s" style="color: #dd1144;">    </span><span class="sh" style="color: #dd1144;">"""</span></span>

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<td class="new_line diff-line-num new" data-linenumber="58" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC58" class="line" lang="python">    <span class="kn" style="font-weight: 600;">import</span> <span class="n" style="color: #333333;">re</span></span>

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<td class="old_line diff-line-num new" data-linenumber="57" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="59" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC59" class="line" lang="python">    <span class="n" style="color: #333333;">ALT_CHARS</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">re</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">compile</span><span class="p">(</span><span class="sa">r</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">^([ACGTNacgtn]+|\*|\.)$</span><span class="sh" style="color: #dd1144;">"</span><span class="p">)</span> <span class="c1" style="color: #999988; font-style: italic;"># straight from the VCF 4.3 spec</span></span>

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<td class="new_line diff-line-num" data-linenumber="60" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC60" class="line" lang="python"></span>

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<td class="old_line diff-line-num" data-linenumber="58" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="new_line diff-line-num" data-linenumber="61" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC61" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">#Programming Note:</span></span>

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<td class="old_line diff-line-num" data-linenumber="59" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="new_line diff-line-num" data-linenumber="62" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC62" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;"># Note on VCF Format</span></span>

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<td class="diff-line-num unfold js-unfold old_line" data-linenumber="73" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="diff-line-num unfold js-unfold new_line" data-linenumber="76" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="line_content match" style="color: rgba(5,5,6,.24); padding: inherit;" bgcolor="#fbfafd">@@ -73,7 +76,7 @@ def read_vcf(vcf_file, ref_file=None):</td>

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<td class="new_line diff-line-num" data-linenumber="76" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC76" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">#     Ex:</span></span>

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<td class="old_line diff-line-num" data-linenumber="74" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="new_line diff-line-num" data-linenumber="77" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC77" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">#       REF     ALT</span></span>

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<td class="new_line diff-line-num" data-linenumber="78" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC78" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">#       A       ATT</span></span>

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<td class="old_line diff-line-num old" data-linenumber="76" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="new_line diff-line-num old" data-linenumber="79" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC76" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">#     First base always match<span class="idiff left right deletion" style="background-color: #fac5cd;">es Ref.</span></span></span>

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<td class="old_line diff-line-num new" data-linenumber="77" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="79" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC79" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">#     First base <span class="idiff left addition" style="background-color: #c7f0d2;">_does not_ </span>always match<span class="idiff right addition" style="background-color: #c7f0d2;"> REF, so there may be a SNP as well</span></span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="77" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="new_line diff-line-num" data-linenumber="80" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC80" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;"># 'No indel'</span></span>

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<td class="old_line diff-line-num" data-linenumber="78" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="new_line diff-line-num" data-linenumber="81" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC81" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">#     Ex:</span></span>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC82" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">#       REF     ALT</span></span>

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<td class="diff-line-num unfold js-unfold old_line" data-linenumber="82" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="diff-line-num unfold js-unfold new_line" data-linenumber="85" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="line_content match" style="color: rgba(5,5,6,.24); padding: inherit;" bgcolor="#fbfafd">@@ -82,6 +85,11 @@ def read_vcf(vcf_file, ref_file=None):</td>

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<td class="old_line diff-line-num" data-linenumber="82" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="new_line diff-line-num" data-linenumber="85" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC85" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">#define here, so that all sub-functions can access them</span></span>

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<td class="new_line diff-line-num" data-linenumber="86" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC86" class="line" lang="python">    <span class="n" style="color: #333333;">sequences</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">defaultdict</span><span class="p">(</span><span class="nb" style="color: #0086b3;">dict</span><span class="p">)</span></span>

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<td class="old_line diff-line-num" data-linenumber="84" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="new_line diff-line-num" data-linenumber="87" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC87" class="line" lang="python">    <span class="n" style="color: #333333;">insertions</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">defaultdict</span><span class="p">(</span><span class="nb" style="color: #0086b3;">dict</span><span class="p">)</span> <span class="c1" style="color: #999988; font-style: italic;">#Currently not used, but kept in case of future use.</span></span>

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<td class="old_line diff-line-num new" data-linenumber="85" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="88" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC88" class="line" lang="python">    <span class="n" style="color: #333333;">metadata</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">{</span></span>

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<td class="old_line diff-line-num new" data-linenumber="85" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="89" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC89" class="line" lang="python">        <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">meta_lines</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="p">[],</span> <span class="c1" style="color: #999988; font-style: italic;"># all the VCF meta_lines, i.e. those starting with '##' (they are left unparsed)</span></span>

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<td class="old_line diff-line-num new" data-linenumber="85" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="90" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC90" class="line" lang="python">        <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">chrom</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="bp" style="color: #999999;">None</span><span class="p">,</span>    <span class="c1" style="color: #999988; font-style: italic;"># chromosome name (we only allow one)</span></span>

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<td class="old_line diff-line-num new" data-linenumber="85" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="91" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC91" class="line" lang="python">        <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">ploidy</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="bp" style="color: #999999;">None</span><span class="p">,</span>   <span class="c1" style="color: #999988; font-style: italic;"># ploidy count -- encoded in how the GT calls are formatted</span></span>

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<td class="new_line diff-line-num new" data-linenumber="92" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC92" class="line" lang="python">    <span class="p">}</span></span>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC93" class="line" lang="python"></span>

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<td class="old_line diff-line-num" data-linenumber="86" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="new_line diff-line-num" data-linenumber="94" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC94" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">#TreeTime handles 2-3 base ambig codes, this will allow that.</span></span>

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<td class="old_line diff-line-num" data-linenumber="87" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="new_line diff-line-num" data-linenumber="95" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC95" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">getAmbigCode</span><span class="p">(</span><span class="n" style="color: #333333;">bp1</span><span class="p">,</span> <span class="n" style="color: #333333;">bp2</span><span class="p">,</span> <span class="n" style="color: #333333;">bp3</span><span class="o" style="font-weight: 600;">=</span><span class="sh" style="color: #dd1144;">""</span><span class="p">):</span></span>

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<td class="diff-line-num unfold js-unfold old_line" data-linenumber="104" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="diff-line-num unfold js-unfold new_line" data-linenumber="112" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="line_content match" style="color: rgba(5,5,6,.24); padding: inherit;" bgcolor="#fbfafd">@@ -104,13 +112,23 @@ def read_vcf(vcf_file, ref_file=None):</td>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC112" class="line" lang="python"></span>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC113" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">#Parses a 'normal' (not hetero or no-call) call depending if insertion+deletion, insertion,</span></span>

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<td class="old_line diff-line-num" data-linenumber="106" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

106

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<td class="new_line diff-line-num" data-linenumber="114" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

114

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC114" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">#deletion, or single bp subsitution</span></span>

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<td class="old_line diff-line-num old" data-linenumber="107" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

107

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<td class="new_line diff-line-num old" data-linenumber="115" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC107" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">parseCall</span><span class="p">(</span><span class="n" style="color: #333333;">snps</span><span class="p">,</span> <span class="n" style="color: #333333;">ins</span><span class="p">,</span> <span class="n" style="color: #333333;">pos</span><span class="p">,</span> <span class="n" style="color: #333333;">ref</span><span class="p">,</span> <span class="n" style="color: #333333;">alt</span><span class="p">):</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="108" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="115" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

115

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC115" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">parse_homozygous_call</span><span class="p">(</span><span class="n" style="color: #333333;">snps</span><span class="p">,</span> <span class="n" style="color: #333333;">ins</span><span class="p">,</span> <span class="n" style="color: #333333;">pos</span><span class="p">,</span> <span class="n" style="color: #333333;">ref</span><span class="p">,</span> <span class="n" style="color: #333333;">alt</span><span class="p">):</span></span>

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<td class="old_line diff-line-num new" data-linenumber="108" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="116" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

116

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC116" class="line" lang="python"></span>

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<td class="old_line diff-line-num new" data-linenumber="108" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="117" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

117

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC117" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;"># Replace missing allele with N(s). See commentary in test_vcf.py::TestNoCallsOrMissing for more details</span></span>

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<td class="old_line diff-line-num new" data-linenumber="108" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="118" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

118

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC118" class="line" lang="python">        <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">alt</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">*</span><span class="sh" style="color: #dd1144;">'</span> <span class="ow" style="font-weight: 600;">or</span> <span class="n" style="color: #333333;">alt</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="108" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="119" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

119

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC119" class="line" lang="python">            <span class="n" style="color: #333333;">alt</span> <span class="o" style="font-weight: 600;">=</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">N</span><span class="sh" style="color: #dd1144;">"</span> <span class="o" style="font-weight: 600;">*</span> <span class="nf" style="color: #990000; font-weight: 600;">len</span><span class="p">(</span><span class="n" style="color: #333333;">ref</span><span class="p">)</span></span>

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<td class="old_line diff-line-num new" data-linenumber="108" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="120" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

120

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC120" class="line" lang="python"></span>

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<td class="old_line diff-line-num" data-linenumber="108" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

108

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<td class="new_line diff-line-num" data-linenumber="121" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

121

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC121" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#Insertion where there are also deletions (special handling)</span></span>

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<td class="old_line diff-line-num" data-linenumber="109" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

109

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<td class="new_line diff-line-num" data-linenumber="122" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

122

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC122" class="line" lang="python">        <span class="k" style="font-weight: 600;">if</span> <span class="nf" style="color: #990000; font-weight: 600;">len</span><span class="p">(</span><span class="n" style="color: #333333;">ref</span><span class="p">)</span> <span class="o" style="font-weight: 600;">></span> <span class="mi" style="color: #009999;">1</span> <span class="ow" style="font-weight: 600;">and</span> <span class="nf" style="color: #990000; font-weight: 600;">len</span><span class="p">(</span><span class="n" style="color: #333333;">alt</span><span class="p">)</span><span class="o" style="font-weight: 600;">></span><span class="nf" style="color: #990000; font-weight: 600;">len</span><span class="p">(</span><span class="n" style="color: #333333;">ref</span><span class="p">):</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="110" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="123" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

123

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC123" class="line" lang="python">            <span class="c1" style="color: #999988; font-style: italic;">## NOTE: the loop below contains a potential double-counting bug. For example,</span></span>

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<td class="old_line diff-line-num new" data-linenumber="110" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="124" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

124

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC124" class="line" lang="python">            <span class="c1" style="color: #999988; font-style: italic;">## REF='TCG' ALT='TCAG' (Example 5.1.3 in the VCF 4.2 spec), then when i=2</span></span>

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<td class="old_line diff-line-num new" data-linenumber="110" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="125" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

125

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC125" class="line" lang="python">            <span class="c1" style="color: #999988; font-style: italic;">## we'll add both snps[pos+2] = 'A' as well as ins[pos+2] = 'AG'. This has been </span></span>

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<td class="new_line diff-line-num new" data-linenumber="126" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC126" class="line" lang="python">            <span class="c1" style="color: #999988; font-style: italic;">## detailed within `test_vcf.py`, as it may also be the expected way to encode</span></span>

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<td class="new_line diff-line-num new" data-linenumber="127" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC127" class="line" lang="python">            <span class="c1" style="color: #999988; font-style: italic;">## insertions within TreeTime</span></span>

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110

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<td class="new_line diff-line-num" data-linenumber="128" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC128" class="line" lang="python">            <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">i</span> <span class="ow" style="font-weight: 600;">in</span> <span class="nf" style="color: #990000; font-weight: 600;">range</span><span class="p">(</span><span class="nf" style="color: #990000; font-weight: 600;">len</span><span class="p">(</span><span class="n" style="color: #333333;">ref</span><span class="p">)):</span></span>

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<td class="old_line diff-line-num" data-linenumber="111" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

111

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<td class="new_line diff-line-num" data-linenumber="129" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC129" class="line" lang="python">                <span class="c1" style="color: #999988; font-style: italic;">#if the pos doesn't match, store in sequences</span></span>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC130" class="line" lang="python">                <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">ref</span><span class="p">[</span><span class="n" style="color: #333333;">i</span><span class="p">]</span> <span class="o" style="font-weight: 600;">!=</span> <span class="n" style="color: #333333;">alt</span><span class="p">[</span><span class="n" style="color: #333333;">i</span><span class="p">]:</span></span>

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<td class="old_line diff-line-num old" data-linenumber="113" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

113

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<td class="new_line diff-line-num old" data-linenumber="131" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC113" class="line" lang="python">                    <span class="n" style="color: #333333;">snps</span><span class="p">[</span><span class="n" style="color: #333333;">pos</span><span class="o" style="font-weight: 600;">+</span><span class="n" style="color: #333333;">i</span><span class="p">]</span> <span class="o" style="font-weight: 600;">=</span> <span class="p"><span class="idiff left deletion" style="background-color: #fac5cd;">(</span></span><span class="n" style="color: #333333;">alt</span><span class="p">[</span><span class="n" style="color: #333333;">i</span><span class="p">]</span><span class="idiff deletion" style="background-color: #fac5cd;"> </span><span class="k" style="font-weight: 600;"><span class="idiff deletion" style="background-color: #fac5cd;">if</span></span><span class="idiff deletion" style="background-color: #fac5cd;"> </span><span class="n" style="color: #333333;"><span class="idiff deletion" style="background-color: #fac5cd;">alt</span></span><span class="p"><span class="idiff deletion" style="background-color: #fac5cd;">[</span></span><span class="n" style="color: #333333;"><span class="idiff deletion" style="background-color: #fac5cd;">i</span></span><span class="p"><span class="idiff deletion" style="background-color: #fac5cd;">]</span></span><span class="idiff deletion" style="background-color: #fac5cd;"> </span><span class="o" style="font-weight: 600;"><span class="idiff deletion" style="background-color: #fac5cd;">!=</span></span><span class="idiff deletion" style="background-color: #fac5cd;"> </span><span class="sh" style="color: #dd1144;"><span class="idiff deletion" style="background-color: #fac5cd;">'</span></span><span class="s" style="color: #dd1144;"><span class="idiff deletion" style="background-color: #fac5cd;">.</span></span><span class="sh" style="color: #dd1144;"><span class="idiff deletion" style="background-color: #fac5cd;">'</span></span><span class="idiff deletion" style="background-color: #fac5cd;"> </span><span class="k" style="font-weight: 600;"><span class="idiff deletion" style="background-color: #fac5cd;">else</span></span><span class="idiff deletion" style="background-color: #fac5cd;"> </span><span class="sh" style="color: #dd1144;"><span class="idiff deletion" style="background-color: #fac5cd;">'</span></span><span class="s" style="color: #dd1144;"><span class="idiff deletion" style="background-color: #fac5cd;">N</span></span><span class="sh" style="color: #dd1144;"><span class="idiff deletion" style="background-color: #fac5cd;">'</span></span><span class="p"><span class="idiff deletion" style="background-color: #fac5cd;">)</span></span><span class="idiff deletion" style="background-color: #fac5cd;"> </span><span class="c1" style="color: #999988; font-style: italic;"><span class="idiff right deletion" style="background-color: #fac5cd;">#'.' = no-call</span></span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC131" class="line" lang="python">                    <span class="n" style="color: #333333;">snps</span><span class="p">[</span><span class="n" style="color: #333333;">pos</span><span class="o" style="font-weight: 600;">+</span><span class="n" style="color: #333333;">i</span><span class="p">]</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">alt</span><span class="p">[</span><span class="n" style="color: #333333;">i</span><span class="p">]</span></span>

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<td class="new_line diff-line-num" data-linenumber="132" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC132" class="line" lang="python">                <span class="c1" style="color: #999988; font-style: italic;">#if about to run out of ref, store rest:</span></span>

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<td class="new_line diff-line-num" data-linenumber="133" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC133" class="line" lang="python">                <span class="nf" style="color: #990000; font-weight: 600;">if </span><span class="p">(</span><span class="n" style="color: #333333;">i</span><span class="o" style="font-weight: 600;">+</span><span class="mi" style="color: #009999;">1</span><span class="p">)</span> <span class="o" style="font-weight: 600;">>=</span> <span class="nf" style="color: #990000; font-weight: 600;">len</span><span class="p">(</span><span class="n" style="color: #333333;">ref</span><span class="p">):</span></span>

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<td class="new_line diff-line-num" data-linenumber="134" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC134" class="line" lang="python">                    <span class="n" style="color: #333333;">ins</span><span class="p">[</span><span class="n" style="color: #333333;">pos</span><span class="o" style="font-weight: 600;">+</span><span class="n" style="color: #333333;">i</span><span class="p">]</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">alt</span><span class="p">[</span><span class="n" style="color: #333333;">i</span><span class="p">:]</span></span>

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<td class="diff-line-num unfold js-unfold old_line" data-linenumber="123" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="diff-line-num unfold js-unfold new_line" data-linenumber="141" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="line_content match" style="color: rgba(5,5,6,.24); padding: inherit;" bgcolor="#fbfafd">@@ -123,17 +141,21 @@ def read_vcf(vcf_file, ref_file=None):</td>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC141" class="line" lang="python">                <span class="c1" style="color: #999988; font-style: italic;">#if not, there may be mutations</span></span>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC142" class="line" lang="python">                <span class="k" style="font-weight: 600;">else</span><span class="p">:</span></span>

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125

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<td class="new_line diff-line-num" data-linenumber="143" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

143

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC143" class="line" lang="python">                    <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">ref</span><span class="p">[</span><span class="n" style="color: #333333;">i</span><span class="p">]</span> <span class="o" style="font-weight: 600;">!=</span> <span class="n" style="color: #333333;">alt</span><span class="p">[</span><span class="n" style="color: #333333;">i</span><span class="p">]:</span></span>

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<td class="old_line diff-line-num old" data-linenumber="126" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

126

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<td class="new_line diff-line-num old" data-linenumber="144" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC126" class="line" lang="python">                        <span class="n" style="color: #333333;">snps</span><span class="p">[</span><span class="n" style="color: #333333;">pos</span><span class="o" style="font-weight: 600;">+</span><span class="n" style="color: #333333;">i</span><span class="p">]</span> <span class="o" style="font-weight: 600;">=</span> <span class="p"><span class="idiff left deletion" style="background-color: #fac5cd;">(</span></span><span class="n" style="color: #333333;">alt</span><span class="p">[</span><span class="n" style="color: #333333;">i</span><span class="p">]</span><span class="idiff deletion" style="background-color: #fac5cd;"> </span><span class="k" style="font-weight: 600;"><span class="idiff deletion" style="background-color: #fac5cd;">if</span></span><span class="idiff deletion" style="background-color: #fac5cd;"> </span><span class="n" style="color: #333333;"><span class="idiff deletion" style="background-color: #fac5cd;">alt</span></span><span class="p"><span class="idiff deletion" style="background-color: #fac5cd;">[</span></span><span class="n" style="color: #333333;"><span class="idiff deletion" style="background-color: #fac5cd;">i</span></span><span class="p"><span class="idiff deletion" style="background-color: #fac5cd;">]</span></span><span class="idiff deletion" style="background-color: #fac5cd;"> </span><span class="o" style="font-weight: 600;"><span class="idiff deletion" style="background-color: #fac5cd;">!=</span></span><span class="idiff deletion" style="background-color: #fac5cd;"> </span><span class="sh" style="color: #dd1144;"><span class="idiff deletion" style="background-color: #fac5cd;">'</span></span><span class="s" style="color: #dd1144;"><span class="idiff deletion" style="background-color: #fac5cd;">.</span></span><span class="sh" style="color: #dd1144;"><span class="idiff deletion" style="background-color: #fac5cd;">'</span></span><span class="idiff deletion" style="background-color: #fac5cd;"> </span><span class="k" style="font-weight: 600;"><span class="idiff deletion" style="background-color: #fac5cd;">else</span></span><span class="idiff deletion" style="background-color: #fac5cd;"> </span><span class="sh" style="color: #dd1144;"><span class="idiff deletion" style="background-color: #fac5cd;">'</span></span><span class="s" style="color: #dd1144;"><span class="idiff deletion" style="background-color: #fac5cd;">N</span></span><span class="sh" style="color: #dd1144;"><span class="idiff deletion" style="background-color: #fac5cd;">'</span></span><span class="p"><span class="idiff deletion" style="background-color: #fac5cd;">)</span></span><span class="idiff deletion" style="background-color: #fac5cd;"> </span><span class="c1" style="color: #999988; font-style: italic;"><span class="idiff right deletion" style="background-color: #fac5cd;">#'.' = no-call</span></span></span>

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<td class="old_line diff-line-num old" data-linenumber="127" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

127

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<td class="new_line diff-line-num old" data-linenumber="144" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC127" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#Insertion</span></span>

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<td class="old_line diff-line-num new" data-linenumber="128" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="144" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

144

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC144" class="line" lang="python">                        <span class="n" style="color: #333333;">snps</span><span class="p">[</span><span class="n" style="color: #333333;">pos</span><span class="o" style="font-weight: 600;">+</span><span class="n" style="color: #333333;">i</span><span class="p">]</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">alt</span><span class="p">[</span><span class="n" style="color: #333333;">i</span><span class="p">]</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="145" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

145

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC145" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#Insertion<span class="idiff left right addition" style="background-color: #c7f0d2;"> + single-base ref</span></span></span>

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128

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<td class="new_line diff-line-num" data-linenumber="146" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

146

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC146" class="line" lang="python">        <span class="k" style="font-weight: 600;">elif</span> <span class="nf" style="color: #990000; font-weight: 600;">len</span><span class="p">(</span><span class="n" style="color: #333333;">alt</span><span class="p">)</span> <span class="o" style="font-weight: 600;">></span> <span class="mi" style="color: #009999;">1</span><span class="p">:</span></span>

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<td class="old_line diff-line-num" data-linenumber="129" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

129

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<td class="new_line diff-line-num" data-linenumber="147" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

147

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC147" class="line" lang="python">            <span class="n" style="color: #333333;">ins</span><span class="p">[</span><span class="n" style="color: #333333;">pos</span><span class="p">]</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">alt</span></span>

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<td class="new_line diff-line-num new" data-linenumber="148" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

148

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC148" class="line" lang="python">            <span class="c1" style="color: #999988; font-style: italic;"># If the first base of the allele doesn't match the ref then we _also_ have a mutation</span></span>

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<td class="new_line diff-line-num new" data-linenumber="149" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC149" class="line" lang="python">            <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">ref</span><span class="p">[</span><span class="mi" style="color: #009999;">0</span><span class="p">]</span><span class="o" style="font-weight: 600;">!=</span><span class="n" style="color: #333333;">alt</span><span class="p">[</span><span class="mi" style="color: #009999;">0</span><span class="p">]:</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="150" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

150

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC150" class="line" lang="python">                <span class="n" style="color: #333333;">snps</span><span class="p">[</span><span class="n" style="color: #333333;">pos</span><span class="p">]</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">alt</span><span class="p">[</span><span class="mi" style="color: #009999;">0</span><span class="p">]</span></span>

</pre></td>

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130

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<td class="new_line diff-line-num" data-linenumber="151" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC151" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#No indel</span></span>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC152" class="line" lang="python">        <span class="k" style="font-weight: 600;">else</span><span class="p">:</span></span>

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132

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<td class="new_line diff-line-num" data-linenumber="153" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC153" class="line" lang="python">            <span class="n" style="color: #333333;">snps</span><span class="p">[</span><span class="n" style="color: #333333;">pos</span><span class="p">]</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">alt</span></span>

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<td class="old_line diff-line-num" data-linenumber="133" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

133

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<td class="new_line diff-line-num" data-linenumber="154" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

154

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC154" class="line" lang="python"></span>

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<td class="old_line diff-line-num" data-linenumber="134" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

134

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<td class="new_line diff-line-num" data-linenumber="155" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

155

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC155" class="line" lang="python"></span>

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<td class="old_line diff-line-num" data-linenumber="135" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

135

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<td class="new_line diff-line-num" data-linenumber="156" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC156" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">#Parses a 'bad' (hetero or no-call) call depending on what it is</span></span>

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<td class="old_line diff-line-num old" data-linenumber="136" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="new_line diff-line-num old" data-linenumber="157" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC136" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">parseBadCall</span><span class="p">(</span><span class="n" style="color: #333333;">gen</span><span class="p">,</span> <span class="n" style="color: #333333;">snps</span><span class="p">,</span> <span class="n" style="color: #333333;">ins</span><span class="p">,</span> <span class="n" style="color: #333333;">pos</span><span class="p">,</span> <span class="n" style="color: #333333;">ref</span><span class="p">,</span> <span class="n" style="color: #333333;">ALT</span><span class="p">):</span></span>

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<td class="old_line diff-line-num new" data-linenumber="137" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="157" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

157

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC157" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">#TODO - consider the situation where the alternate allele base(s) is '*' (done for the homozygous case)</span></span>

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<td class="old_line diff-line-num new" data-linenumber="137" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="158" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC158" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">parse_heterozygous_call</span><span class="p">(</span><span class="n" style="color: #333333;">gen</span><span class="p">,</span> <span class="n" style="color: #333333;">snps</span><span class="p">,</span> <span class="n" style="color: #333333;">ins</span><span class="p">,</span> <span class="n" style="color: #333333;">pos</span><span class="p">,</span> <span class="n" style="color: #333333;">ref</span><span class="p">,</span> <span class="n" style="color: #333333;">ALT</span><span class="p">):</span></span>

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<td class="new_line diff-line-num" data-linenumber="159" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC159" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#Deletion</span></span>

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<td class="new_line diff-line-num" data-linenumber="160" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC160" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#   REF     ALT     Seq1    Seq2    Seq3</span></span>

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<td class="old_line diff-line-num" data-linenumber="139" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="new_line diff-line-num" data-linenumber="161" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC161" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#   GCC     G       1/1     0/1     ./.</span></span>

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<td class="diff-line-num unfold js-unfold old_line" data-linenumber="173" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="diff-line-num unfold js-unfold new_line" data-linenumber="195" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="line_content match" style="color: rgba(5,5,6,.24); padding: inherit;" bgcolor="#fbfafd">@@ -173,90 +195,135 @@ def read_vcf(vcf_file, ref_file=None):</td>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC195" class="line" lang="python">            <span class="n" style="color: #333333;">snps</span><span class="p">[</span><span class="n" style="color: #333333;">pos</span><span class="p">]</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">alt</span></span>

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<td class="old_line diff-line-num" data-linenumber="174" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="new_line diff-line-num" data-linenumber="196" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC196" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#else a no-call insertion, so ignore.</span></span>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC197" class="line" lang="python"></span>

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<td class="new_line diff-line-num new" data-linenumber="198" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC198" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">validate_alt</span><span class="p">(</span><span class="n" style="color: #333333;">alt</span><span class="p">):</span></span>

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<td class="old_line diff-line-num new" data-linenumber="176" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="199" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

199

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC199" class="line" lang="python">        <span class="sh" style="color: #dd1144;">"""</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="176" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="200" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

200

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC200" class="line" lang="python"><span class="s" style="color: #dd1144;">        from the VCF 4.3 spec:</span></span>

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<td class="old_line diff-line-num new" data-linenumber="176" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="201" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

201

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC201" class="line" lang="python"><span class="s" style="color: #dd1144;">        > the ALT field must be a symbolic allele, or a breakend replacement string,</span></span>

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<td class="old_line diff-line-num new" data-linenumber="176" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="202" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

202

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC202" class="line" lang="python"><span class="s" style="color: #dd1144;">        > or match the regular expression [see ALT_CHARS regex, above]</span></span>

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<td class="old_line diff-line-num new" data-linenumber="176" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="203" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

203

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC203" class="line" lang="python"><span class="s" style="color: #dd1144;">        Since we only consider GT variation, the symbolic alleles and breakends aren</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">t</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="176" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="204" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

204

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC204" class="line" lang="python"><span class="s" style="color: #dd1144;">        relevant for us.</span></span>

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<td class="old_line diff-line-num new" data-linenumber="176" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="205" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

205

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC205" class="line" lang="python"></span>

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<td class="old_line diff-line-num new" data-linenumber="176" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="206" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

206

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC206" class="line" lang="python"><span class="s" style="color: #dd1144;">        The spec also states:</span></span>

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<td class="old_line diff-line-num new" data-linenumber="176" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="207" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

207

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC207" class="line" lang="python"><span class="s" style="color: #dd1144;">        > Tools processing VCF files are not required to preserve case in the allele String</span></span>

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<td class="old_line diff-line-num new" data-linenumber="176" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="208" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

208

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC208" class="line" lang="python"><span class="s" style="color: #dd1144;">        </span></span>

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<td class="old_line diff-line-num new" data-linenumber="176" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="209" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

209

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC209" class="line" lang="python"><span class="s" style="color: #dd1144;">        Return the uppercase allele bases (string) _or_ None if it fails validation</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="176" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="210" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC210" class="line" lang="python"><span class="s" style="color: #dd1144;">        </span><span class="sh" style="color: #dd1144;">"""</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="176" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="211" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

211

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC211" class="line" lang="python">        <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">ALT_CHARS</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">match</span><span class="p">(</span><span class="n" style="color: #333333;">alt</span><span class="p">):</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="176" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="212" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC212" class="line" lang="python">            <span class="k" style="font-weight: 600;">return</span> <span class="n" style="color: #333333;">alt</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">upper</span><span class="p">()</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="176" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="213" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC213" class="line" lang="python">        <span class="k" style="font-weight: 600;">else</span><span class="p">:</span></span>

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<td class="old_line diff-line-num new" data-linenumber="176" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="214" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

214

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC214" class="line" lang="python">            <span class="nf" style="color: #990000; font-weight: 600;">print</span><span class="p">(</span><span class="sa">f</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">WARNING: Encountered invalid allele base(s) </span><span class="si" style="color: #dd1144;">{</span><span class="n" style="color: #333333;">alt</span><span class="si" style="color: #dd1144;">!r}</span><span class="s" style="color: #dd1144;">. Skipping...</span><span class="sh" style="color: #dd1144;">"</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="176" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="215" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

215

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC215" class="line" lang="python">            <span class="k" style="font-weight: 600;">return</span> <span class="bp" style="color: #999999;">None</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="176" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

176

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<td class="new_line diff-line-num" data-linenumber="216" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

216

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC216" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="177" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

177

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<td class="new_line diff-line-num" data-linenumber="217" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

217

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC217" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">#House code is *much* faster than pyvcf because we don't care about all info</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="178" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

178

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<td class="new_line diff-line-num" data-linenumber="218" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

218

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC218" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">#about coverage, quality, counts, etc, which pyvcf goes to effort to parse</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="179" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

179

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<td class="new_line diff-line-num" data-linenumber="219" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

219

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC219" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">#(and it's not easy as there's no standard ordering). Custom code can completely</span></span>

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<td class="old_line diff-line-num" data-linenumber="180" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

180

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<td class="new_line diff-line-num" data-linenumber="220" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

220

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC220" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">#ignore all of this.</span></span>

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<td class="old_line diff-line-num old" data-linenumber="181" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

181

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<td class="new_line diff-line-num old" data-linenumber="221" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC181" class="line" lang="python">    <span class="kn" style="font-weight: 600;">import</span> <span class="n" style="color: #333333;">gzip</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="182" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

182

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<td class="new_line diff-line-num" data-linenumber="221" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

221

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC221" class="line" lang="python">    <span class="kn" style="font-weight: 600;">from</span> <span class="n" style="color: #333333;">Bio</span> <span class="kn" style="font-weight: 600;">import</span> <span class="n" style="color: #333333;">SeqIO</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="183" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

183

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<td class="new_line diff-line-num old" data-linenumber="222" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC183" class="line" lang="python">    <span class="kn" style="font-weight: 600;">import</span> <span class="n" style="color: #333333;">numpy</span> <span class="k" style="font-weight: 600;">as</span> <span class="n" style="color: #333333;">np</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="184" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

184

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<td class="new_line diff-line-num old" data-linenumber="222" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC184" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="185" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

185

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<td class="new_line diff-line-num old" data-linenumber="222" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC185" class="line" lang="python">    <span class="n" style="color: #333333;">nsamp</span> <span class="o" style="font-weight: 600;">=</span> <span class="mi" style="color: #009999;">0</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="186" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

186

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<td class="new_line diff-line-num old" data-linenumber="222" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC186" class="line" lang="python">    <span class="n" style="color: #333333;">posLoc</span> <span class="o" style="font-weight: 600;">=</span> <span class="mi" style="color: #009999;">0</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="187" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

187

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<td class="new_line diff-line-num old" data-linenumber="222" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC187" class="line" lang="python">    <span class="n" style="color: #333333;">refLoc</span> <span class="o" style="font-weight: 600;">=</span> <span class="mi" style="color: #009999;">0</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="188" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

188

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<td class="new_line diff-line-num old" data-linenumber="222" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC188" class="line" lang="python">    <span class="n" style="color: #333333;">altLoc</span> <span class="o" style="font-weight: 600;">=</span> <span class="mi" style="color: #009999;">0</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="189" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

189

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<td class="new_line diff-line-num old" data-linenumber="222" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC189" class="line" lang="python">    <span class="n" style="color: #333333;">sampLoc</span> <span class="o" style="font-weight: 600;">=</span> <span class="mi" style="color: #009999;">9</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="190" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

190

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<td class="new_line diff-line-num" data-linenumber="222" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

222

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC222" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="191" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

191

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<td class="new_line diff-line-num" data-linenumber="223" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

223

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC223" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">#Use different openers depending on whether compressed</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="192" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

192

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<td class="new_line diff-line-num" data-linenumber="224" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

224

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC224" class="line" lang="python">    <span class="n" style="color: #333333;">opn</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">gzip</span><span class="p">.</span><span class="nb" style="color: #0086b3;">open</span> <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">vcf_file</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">endswith</span><span class="p">((</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">.gz</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">.GZ</span><span class="sh" style="color: #dd1144;">'</span><span class="p">))</span> <span class="k" style="font-weight: 600;">else</span> <span class="nb" style="color: #0086b3;">open</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="193" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

193

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<td class="new_line diff-line-num" data-linenumber="225" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

225

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC225" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="194" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

194

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<td class="new_line diff-line-num" data-linenumber="226" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

226

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC226" class="line" lang="python">    <span class="k" style="font-weight: 600;">with</span> <span class="nf" style="color: #990000; font-weight: 600;">opn</span><span class="p">(</span><span class="n" style="color: #333333;">vcf_file</span><span class="p">,</span> <span class="n" style="color: #333333;">mode</span><span class="o" style="font-weight: 600;">=</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">rt</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span> <span class="k" style="font-weight: 600;">as</span> <span class="n" style="color: #333333;">f</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="195" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

195

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC195" class="line" lang="python">        <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">line</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">f</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="196" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

196

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC196" class="line" lang="python">            <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">line</span><span class="p">[</span><span class="mi" style="color: #009999;">0</span><span class="p">]</span> <span class="o" style="font-weight: 600;">!=</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">#</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="197" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

197

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC197" class="line" lang="python">                <span class="c1" style="color: #999988; font-style: italic;">#actual data - most common so first in 'if-list'!</span></span>

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<td class="old_line diff-line-num old" data-linenumber="198" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

198

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC198" class="line" lang="python">                <span class="n" style="color: #333333;">dat</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">line</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">strip</span><span class="p">().</span><span class="nf" style="color: #990000; font-weight: 600;">split</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="se" style="color: #dd1144;">\t</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="199" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

199

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC199" class="line" lang="python">                <span class="n" style="color: #333333;">POS</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">int</span><span class="p">(</span><span class="n" style="color: #333333;">dat</span><span class="p">[</span><span class="n" style="color: #333333;">posLoc</span><span class="p">])</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="200" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

200

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC200" class="line" lang="python">                <span class="n" style="color: #333333;">REF</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">dat</span><span class="p">[</span><span class="n" style="color: #333333;">refLoc</span><span class="p">]</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="201" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

201

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC201" class="line" lang="python">                <span class="n" style="color: #333333;">ALT</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">dat</span><span class="p">[</span><span class="n" style="color: #333333;">altLoc</span><span class="p">].</span><span class="nf" style="color: #990000; font-weight: 600;">split</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">,</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="202" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

202

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC202" class="line" lang="python">                <span class="n" style="color: #333333;">calls</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">np</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">array</span><span class="p">(</span><span class="n" style="color: #333333;">dat</span><span class="p">[</span><span class="n" style="color: #333333;">sampLoc</span><span class="p">:])</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="203" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

203

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC203" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="204" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

204

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC204" class="line" lang="python">                <span class="c1" style="color: #999988; font-style: italic;">#get samples that differ from Ref at this site</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="205" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

205

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC205" class="line" lang="python">                <span class="n" style="color: #333333;">recCalls</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">{}</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="206" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

206

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC206" class="line" lang="python">                <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">sname</span><span class="p">,</span> <span class="n" style="color: #333333;">sa</span> <span class="ow" style="font-weight: 600;">in</span> <span class="nf" style="color: #990000; font-weight: 600;">zip</span><span class="p">(</span><span class="n" style="color: #333333;">samps</span><span class="p">,</span> <span class="n" style="color: #333333;">calls</span><span class="p">):</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="207" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

207

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC207" class="line" lang="python">                    <span class="k" style="font-weight: 600;">if</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">:</span><span class="sh" style="color: #dd1144;">'</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">sa</span><span class="p">:</span> <span class="c1" style="color: #999988; font-style: italic;">#if proper VCF file (followed by quality/coverage info)</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="208" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

208

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC208" class="line" lang="python">                        <span class="n" style="color: #333333;">gt</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">sa</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">split</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">:</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)[</span><span class="mi" style="color: #009999;">0</span><span class="p">]</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="209" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

209

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC209" class="line" lang="python">                    <span class="k" style="font-weight: 600;">else</span><span class="p">:</span> <span class="c1" style="color: #999988; font-style: italic;">#if 'pseudo' VCF file (nextstrain output, or otherwise stripped)</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="210" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

210

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC210" class="line" lang="python">                        <span class="n" style="color: #333333;">gt</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">sa</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="211" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

211

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC211" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="212" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

212

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC212" class="line" lang="python">                    <span class="c1" style="color: #999988; font-style: italic;"># convert haploid calls to pseudo diploid</span></span>

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<td class="old_line diff-line-num old" data-linenumber="213" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

213

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC213" class="line" lang="python">                    <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">gt</span> <span class="o" style="font-weight: 600;">==</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="214" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

214

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC214" class="line" lang="python">                        <span class="n" style="color: #333333;">gt</span> <span class="o" style="font-weight: 600;">=</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">0/0</span><span class="sh" style="color: #dd1144;">'</span></span>

</pre></td>

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC215" class="line" lang="python">                    <span class="k" style="font-weight: 600;">elif</span> <span class="n" style="color: #333333;">gt</span> <span class="o" style="font-weight: 600;">==</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span></span>

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC216" class="line" lang="python">                        <span class="n" style="color: #333333;">gt</span> <span class="o" style="font-weight: 600;">=</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">1/1</span><span class="sh" style="color: #dd1144;">'</span></span>

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<td class="old_line diff-line-num old" data-linenumber="217" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC217" class="line" lang="python">                    <span class="k" style="font-weight: 600;">elif</span> <span class="n" style="color: #333333;">gt</span> <span class="o" style="font-weight: 600;">==</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span></span>

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<td class="old_line diff-line-num old" data-linenumber="218" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

218

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC218" class="line" lang="python">                        <span class="n" style="color: #333333;">gt</span> <span class="o" style="font-weight: 600;">=</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">./.</span><span class="sh" style="color: #dd1144;">'</span></span>

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<td class="old_line diff-line-num old" data-linenumber="219" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

219

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC219" class="line" lang="python"></span>

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<td class="old_line diff-line-num old" data-linenumber="220" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC220" class="line" lang="python">                    <span class="c1" style="color: #999988; font-style: italic;">#ignore if ref call: '.' or '0/0', depending on VCF</span></span>

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC221" class="line" lang="python">                    <span class="nf" style="color: #990000; font-weight: 600;">if </span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">/</span><span class="sh" style="color: #dd1144;">'</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">gt</span> <span class="ow" style="font-weight: 600;">and</span> <span class="n" style="color: #333333;">gt</span> <span class="o" style="font-weight: 600;">!=</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">0/0</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span> <span class="ow" style="font-weight: 600;">or</span> <span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">|</span><span class="sh" style="color: #dd1144;">'</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">gt</span> <span class="ow" style="font-weight: 600;">and</span> <span class="n" style="color: #333333;">gt</span> <span class="o" style="font-weight: 600;">!=</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">0|0</span><span class="sh" style="color: #dd1144;">'</span><span class="p">):</span></span>

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<td class="old_line diff-line-num old" data-linenumber="222" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC222" class="line" lang="python">                        <span class="n" style="color: #333333;">recCalls</span><span class="p">[</span><span class="n" style="color: #333333;">sname</span><span class="p">]</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">gt</span></span>

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC223" class="line" lang="python"></span>

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<td class="old_line diff-line-num old" data-linenumber="224" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC224" class="line" lang="python">                <span class="c1" style="color: #999988; font-style: italic;">#store the position and the alt</span></span>

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<td class="old_line diff-line-num old" data-linenumber="225" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC225" class="line" lang="python">                <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">seq</span><span class="p">,</span> <span class="n" style="color: #333333;">gen</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">recCalls</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">items</span><span class="p">():</span></span>

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<td class="old_line diff-line-num old" data-linenumber="226" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC226" class="line" lang="python">                    <span class="n" style="color: #333333;">ref</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">REF</span></span>

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<td class="old_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC227" class="line" lang="python">                    <span class="n" style="color: #333333;">pos</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">POS</span><span class="o" style="font-weight: 600;">-</span><span class="mi" style="color: #009999;">1</span>     <span class="c1" style="color: #999988; font-style: italic;">#VCF numbering starts from 1, but Reference seq numbering</span></span>

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC228" class="line" lang="python">                                    <span class="c1" style="color: #999988; font-style: italic;">#will be from 0 because it's python!</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="229" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC229" class="line" lang="python">                    <span class="c1" style="color: #999988; font-style: italic;">#Accepts only calls that are 1/1, 2/2 etc. Rejects hets and no-calls</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="230" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

230

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC230" class="line" lang="python">                    <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">gen</span><span class="p">[</span><span class="mi" style="color: #009999;">0</span><span class="p">]</span> <span class="o" style="font-weight: 600;">!=</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">'</span> <span class="ow" style="font-weight: 600;">and</span> <span class="n" style="color: #333333;">gen</span><span class="p">[</span><span class="mi" style="color: #009999;">2</span><span class="p">]</span> <span class="o" style="font-weight: 600;">!=</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">0</span><span class="sh" style="color: #dd1144;">'</span> <span class="ow" style="font-weight: 600;">and</span> <span class="n" style="color: #333333;">gen</span><span class="p">[</span><span class="mi" style="color: #009999;">0</span><span class="p">]</span> <span class="o" style="font-weight: 600;">!=</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">'</span> <span class="ow" style="font-weight: 600;">and</span> <span class="n" style="color: #333333;">gen</span><span class="p">[</span><span class="mi" style="color: #009999;">2</span><span class="p">]</span> <span class="o" style="font-weight: 600;">!=</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="231" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

231

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC231" class="line" lang="python">                        <span class="n" style="color: #333333;">alt</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">str</span><span class="p">(</span><span class="n" style="color: #333333;">ALT</span><span class="p">[</span><span class="nf" style="color: #990000; font-weight: 600;">int</span><span class="p">(</span><span class="n" style="color: #333333;">gen</span><span class="p">[</span><span class="mi" style="color: #009999;">0</span><span class="p">])</span><span class="o" style="font-weight: 600;">-</span><span class="mi" style="color: #009999;">1</span><span class="p">])</span>   <span class="c1" style="color: #999988; font-style: italic;">#get the index of the alternate</span></span>

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<td class="old_line diff-line-num old" data-linenumber="232" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

232

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC232" class="line" lang="python">                        <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">seq</span> <span class="ow" style="font-weight: 600;">not</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">sequences</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">keys</span><span class="p">():</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="233" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

233

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC233" class="line" lang="python">                            <span class="n" style="color: #333333;">sequences</span><span class="p">[</span><span class="n" style="color: #333333;">seq</span><span class="p">]</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">{}</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="234" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

234

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC234" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="235" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

235

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC235" class="line" lang="python">                        <span class="nf" style="color: #990000; font-weight: 600;">parseCall</span><span class="p">(</span><span class="n" style="color: #333333;">sequences</span><span class="p">[</span><span class="n" style="color: #333333;">seq</span><span class="p">],</span><span class="n" style="color: #333333;">insertions</span><span class="p">[</span><span class="n" style="color: #333333;">seq</span><span class="p">],</span> <span class="n" style="color: #333333;">pos</span><span class="p">,</span> <span class="n" style="color: #333333;">ref</span><span class="p">,</span> <span class="n" style="color: #333333;">alt</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="236" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

236

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC236" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="237" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

237

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC237" class="line" lang="python">                    <span class="c1" style="color: #999988; font-style: italic;">#If is heterozygote call (0/1) or no call (./.)</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="238" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

238

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC238" class="line" lang="python">                    <span class="k" style="font-weight: 600;">else</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="239" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

239

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC239" class="line" lang="python">                        <span class="c1" style="color: #999988; font-style: italic;">#alt will differ here depending on het or no-call, must pass original</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="240" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="new_line diff-line-num old" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC240" class="line" lang="python">                        <span class="nf" style="color: #990000; font-weight: 600;">parseBadCall</span><span class="p">(</span><span class="n" style="color: #333333;">gen</span><span class="p">,</span> <span class="n" style="color: #333333;">sequences</span><span class="p">[</span><span class="n" style="color: #333333;">seq</span><span class="p">],</span><span class="n" style="color: #333333;">insertions</span><span class="p">[</span><span class="n" style="color: #333333;">seq</span><span class="p">],</span> <span class="n" style="color: #333333;">pos</span><span class="p">,</span> <span class="n" style="color: #333333;">ref</span><span class="p">,</span> <span class="n" style="color: #333333;">ALT</span><span class="p">)</span></span>

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<td class="new_line diff-line-num new" data-linenumber="227" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC227" class="line" lang="python">        <span class="n" style="color: #333333;">current_block</span> <span class="o" style="font-weight: 600;">=</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">meta-information</span><span class="sh" style="color: #dd1144;">"</span> <span class="c1" style="color: #999988; font-style: italic;"># The start of VCF files is the meta-information (lines starting with ##)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="241" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="228" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC228" class="line" lang="python">        <span class="n" style="color: #333333;">header</span><span class="p">,</span><span class="n" style="color: #333333;">samps</span><span class="p">,</span><span class="n" style="color: #333333;">nsamp</span><span class="o" style="font-weight: 600;">=</span><span class="bp" style="color: #999999;">None</span><span class="p">,</span><span class="bp" style="color: #999999;">None</span><span class="p">,</span><span class="bp" style="color: #999999;">None</span></span>

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<td class="new_line diff-line-num" data-linenumber="229" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC229" class="line" lang="python"></span>

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<td class="old_line diff-line-num old" data-linenumber="242" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

242

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<td class="new_line diff-line-num old" data-linenumber="230" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC242" class="line" lang="python">            <span class="k" style="font-weight: 600;">elif</span> <span class="n" style="color: #333333;">line</span><span class="p">[</span><span class="mi" style="color: #009999;">0</span><span class="p">]</span> <span class="o" style="font-weight: 600;">==</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">#</span><span class="sh" style="color: #dd1144;">'</span> <span class="ow" style="font-weight: 600;">and</span> <span class="n" style="color: #333333;">line</span><span class="p">[</span><span class="mi" style="color: #009999;">1</span><span class="p">]</span> <span class="o" style="font-weight: 600;">==</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">C</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span></span>

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<td class="old_line diff-line-num old" data-linenumber="243" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="new_line diff-line-num old" data-linenumber="230" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC243" class="line" lang="python">                <span class="c1" style="color: #999988; font-style: italic;">#header line, get all the information</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="244" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="230" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

230

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC230" class="line" lang="python">        <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">line</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">f</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="244" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="231" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC231" class="line" lang="python">            <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">line</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">startswith</span><span class="p">(</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">##</span><span class="sh" style="color: #dd1144;">"</span><span class="p">):</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="244" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="232" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC232" class="line" lang="python">                <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">current_block</span><span class="o" style="font-weight: 600;">!=</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">meta-information</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="244" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="233" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC233" class="line" lang="python">                    <span class="k" style="font-weight: 600;">raise</span> <span class="nc" style="color: #445588; font-weight: 600;">TreeTimeError</span><span class="p">(</span><span class="sa">f</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">Malformed VCF file </span><span class="si" style="color: #dd1144;">{</span><span class="n" style="color: #333333;">vcf_file</span><span class="si" style="color: #dd1144;">!r}</span><span class="s" style="color: #dd1144;"> - all the meta-information (lines starting with ##) must appear at the top of the file.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">)</span></span>

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<td class="old_line diff-line-num new" data-linenumber="244" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="234" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC234" class="line" lang="python">                <span class="n" style="color: #333333;">metadata</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">meta_lines</span><span class="sh" style="color: #dd1144;">'</span><span class="p">].</span><span class="nf" style="color: #990000; font-weight: 600;">append</span><span class="p">(</span><span class="n" style="color: #333333;">line</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">strip</span><span class="p">())</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="244" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="235" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC235" class="line" lang="python">            <span class="k" style="font-weight: 600;">elif</span> <span class="n" style="color: #333333;">line</span><span class="p">[</span><span class="mi" style="color: #009999;">0</span><span class="p">]</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">#</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span></span>

</pre></td>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC236" class="line" lang="python">                <span class="n" style="color: #333333;">mandatory_fields</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">CHROM</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">POS</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">ID</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">REF</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">ALT</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">QUAL</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">FILTER</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">INFO</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">FORMAT</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span></span>

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<td class="new_line diff-line-num new" data-linenumber="237" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC237" class="line" lang="python">                <span class="c1" style="color: #999988; font-style: italic;"># Note that FORMAT isn't mandatory unless genotype data is present. But every VCF we deal with has genotype data - that's the point!</span></span>

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<td class="new_line diff-line-num new" data-linenumber="238" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC238" class="line" lang="python">                <span class="n" style="color: #333333;">header_start</span> <span class="o" style="font-weight: 600;">=</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">#</span><span class="sh" style="color: #dd1144;">"</span><span class="o" style="font-weight: 600;">+</span><span class="sh" style="color: #dd1144;">"</span><span class="se" style="color: #dd1144;">\t</span><span class="sh" style="color: #dd1144;">"</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">join</span><span class="p">(</span><span class="n" style="color: #333333;">mandatory_fields</span><span class="p">)</span></span>

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<td class="new_line diff-line-num new" data-linenumber="239" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC239" class="line" lang="python">                <span class="k" style="font-weight: 600;">if</span> <span class="ow" style="font-weight: 600;">not</span> <span class="n" style="color: #333333;">line</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">startswith</span><span class="p">(</span><span class="n" style="color: #333333;">header_start</span><span class="p">):</span></span>

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<td class="old_line diff-line-num new" data-linenumber="244" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="240" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC240" class="line" lang="python">                    <span class="k" style="font-weight: 600;">raise</span> <span class="nc" style="color: #445588; font-weight: 600;">TreeTimeError</span><span class="p">(</span><span class="sa">f</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">Malformed VCF file </span><span class="si" style="color: #dd1144;">{</span><span class="n" style="color: #333333;">vcf_file</span><span class="si" style="color: #dd1144;">!r}</span><span class="s" style="color: #dd1144;"> - the header line must start with </span><span class="si" style="color: #dd1144;">{</span><span class="n" style="color: #333333;">header_start</span><span class="si" style="color: #dd1144;">}</span><span class="sh" style="color: #dd1144;">"</span><span class="p">)</span></span>

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<td class="new_line diff-line-num new" data-linenumber="241" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC241" class="line" lang="python">                <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">current_block</span><span class="o" style="font-weight: 600;">!=</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">meta-information</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="244" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="242" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC242" class="line" lang="python">                    <span class="k" style="font-weight: 600;">raise</span> <span class="nc" style="color: #445588; font-weight: 600;">TreeTimeError</span><span class="p">(</span><span class="sa">f</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">Malformed VCF file </span><span class="si" style="color: #dd1144;">{</span><span class="n" style="color: #333333;">vcf_file</span><span class="si" style="color: #dd1144;">!r}</span><span class="s" style="color: #dd1144;"> - the header must immediately follow the meta-information lines</span><span class="sh" style="color: #dd1144;">"</span><span class="p">)</span></span>

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<td class="new_line diff-line-num new" data-linenumber="243" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC243" class="line" lang="python">                <span class="n" style="color: #333333;">current_block</span> <span class="o" style="font-weight: 600;">=</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">header</span><span class="sh" style="color: #dd1144;">'</span></span>

</pre></td>

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<td class="new_line diff-line-num" data-linenumber="244" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC244" class="line" lang="python">                <span class="n" style="color: #333333;">header</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">line</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">strip</span><span class="p">().</span><span class="nf" style="color: #990000; font-weight: 600;">split</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="se" style="color: #dd1144;">\t</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

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<td class="new_line diff-line-num old" data-linenumber="245" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC245" class="line" lang="python">                <span class="n" style="color: #333333;">posLoc</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">header</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">index</span><span class="p">(</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">POS</span><span class="sh" style="color: #dd1144;">"</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="246" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="new_line diff-line-num old" data-linenumber="245" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC246" class="line" lang="python">                <span class="n" style="color: #333333;">refLoc</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">header</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">index</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">REF</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

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<td class="new_line diff-line-num old" data-linenumber="245" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC247" class="line" lang="python">                <span class="n" style="color: #333333;">altLoc</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">header</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">index</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">ALT</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="248" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

248

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<td class="new_line diff-line-num old" data-linenumber="245" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC248" class="line" lang="python">                <span class="n" style="color: #333333;">sampLoc</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">header</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">index</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">FORMAT</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span><span class="o" style="font-weight: 600;">+</span><span class="mi" style="color: #009999;">1</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="249" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="new_line diff-line-num old" data-linenumber="245" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC249" class="line" lang="python">                <span class="n" style="color: #333333;">samps</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">header</span><span class="p">[</span><span class="n" style="color: #333333;">sampLoc</span><span class="p">:]</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="250" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="new_line diff-line-num old" data-linenumber="245" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC250" class="line" lang="python">                <span class="n" style="color: #333333;">samps</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">[</span> <span class="n" style="color: #333333;">x</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">strip</span><span class="p">()</span> <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">x</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">samps</span> <span class="p">]</span> <span class="c1" style="color: #999988; font-style: italic;">#ensure no leading/trailing spaces</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="251" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="245" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC245" class="line" lang="python">                <span class="n" style="color: #333333;">samps</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">[</span> <span class="n" style="color: #333333;">x</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">strip</span><span class="p">()</span> <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">x</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">header</span><span class="p">[</span><span class="mi" style="color: #009999;">9</span><span class="p">:]</span> <span class="p">]</span> <span class="c1" style="color: #999988; font-style: italic;">#ensure no leading/trailing spaces</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="251" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="new_line diff-line-num" data-linenumber="246" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC246" class="line" lang="python">                <span class="n" style="color: #333333;">nsamp</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">len</span><span class="p">(</span><span class="n" style="color: #333333;">samps</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="252" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="247" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC247" class="line" lang="python">                <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">sample_name</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">samps</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="252" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="248" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC248" class="line" lang="python">                    <span class="n" style="color: #333333;">sequences</span><span class="p">[</span><span class="n" style="color: #333333;">sample_name</span><span class="p">]</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">{}</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="252" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="249" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC249" class="line" lang="python">            <span class="k" style="font-weight: 600;">else</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="252" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="250" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC250" class="line" lang="python">                <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">current_block</span><span class="o" style="font-weight: 600;">!=</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">header</span><span class="sh" style="color: #dd1144;">'</span> <span class="ow" style="font-weight: 600;">and</span> <span class="n" style="color: #333333;">current_block</span><span class="o" style="font-weight: 600;">!=</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">data-lines</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="252" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="251" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

251

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC251" class="line" lang="python">                    <span class="k" style="font-weight: 600;">raise</span> <span class="nc" style="color: #445588; font-weight: 600;">TreeTimeError</span><span class="p">(</span><span class="sa">f</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">Malformed VCF file </span><span class="si" style="color: #dd1144;">{</span><span class="n" style="color: #333333;">vcf_file</span><span class="si" style="color: #dd1144;">!r}</span><span class="s" style="color: #dd1144;"> - the data lines must follow the header line</span><span class="sh" style="color: #dd1144;">"</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="252" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="252" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC252" class="line" lang="python">                <span class="n" style="color: #333333;">current_block</span><span class="o" style="font-weight: 600;">=</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">data-lines</span><span class="sh" style="color: #dd1144;">'</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="252" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC253" class="line" lang="python">                <span class="n" style="color: #333333;">l</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">line</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">strip</span><span class="p">()</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="252" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="254" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

254

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC254" class="line" lang="python">                <span class="k" style="font-weight: 600;">if</span> <span class="ow" style="font-weight: 600;">not</span> <span class="n" style="color: #333333;">l</span><span class="p">:</span> <span class="c1" style="color: #999988; font-style: italic;"># empty line</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="252" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="255" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

255

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC255" class="line" lang="python">                    <span class="k" style="font-weight: 600;">continue</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="252" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="256" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

256

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC256" class="line" lang="python">                <span class="n" style="color: #333333;">dat</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">l</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">split</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="se" style="color: #dd1144;">\t</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="252" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="257" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

257

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC257" class="line" lang="python">                <span class="n" style="color: #333333;">chrom</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">str</span><span class="p">(</span><span class="n" style="color: #333333;">dat</span><span class="p">[</span><span class="mi" style="color: #009999;">0</span><span class="p">])</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="252" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="258" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

258

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC258" class="line" lang="python">                <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">metadata</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">chrom</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span> <span class="ow" style="font-weight: 600;">is</span> <span class="bp" style="color: #999999;">None</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="252" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="259" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

259

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC259" class="line" lang="python">                    <span class="n" style="color: #333333;">metadata</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">chrom</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">chrom</span></span>

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<td class="old_line diff-line-num new" data-linenumber="252" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="260" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

260

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC260" class="line" lang="python">                <span class="k" style="font-weight: 600;">elif</span> <span class="n" style="color: #333333;">metadata</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">chrom</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span><span class="o" style="font-weight: 600;">!=</span><span class="n" style="color: #333333;">chrom</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="252" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="261" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC261" class="line" lang="python">                    <span class="k" style="font-weight: 600;">raise</span> <span class="nc" style="color: #445588; font-weight: 600;">TreeTimeError</span><span class="p">(</span><span class="sa">f</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">The VCF file </span><span class="si" style="color: #dd1144;">{</span><span class="n" style="color: #333333;">vcf_file</span><span class="si" style="color: #dd1144;">!r}</span><span class="s" style="color: #dd1144;"> contains multiple chromosomes. TreeTime can not yet handle this.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="252" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="262" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC262" class="line" lang="python">                <span class="n" style="color: #333333;">pos</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">int</span><span class="p">(</span><span class="n" style="color: #333333;">dat</span><span class="p">[</span><span class="mi" style="color: #009999;">1</span><span class="p">])</span><span class="o" style="font-weight: 600;">-</span><span class="mi" style="color: #009999;">1</span> <span class="c1" style="color: #999988; font-style: italic;"># Convert VCF 1-based to python 0-based</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="263" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC263" class="line" lang="python">                <span class="n" style="color: #333333;">REF</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">dat</span><span class="p">[</span><span class="mi" style="color: #009999;">3</span><span class="p">]</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="252" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="264" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

264

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC264" class="line" lang="python">                <span class="n" style="color: #333333;">ALT</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">dat</span><span class="p">[</span><span class="mi" style="color: #009999;">4</span><span class="p">].</span><span class="nf" style="color: #990000; font-weight: 600;">split</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">,</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span> <span class="c1" style="color: #999988; font-style: italic;"># List of alternate alleles (strings)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="252" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="265" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

265

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC265" class="line" lang="python">                <span class="n" style="color: #333333;">calls</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">np</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">array</span><span class="p">(</span><span class="n" style="color: #333333;">dat</span><span class="p">[</span><span class="mi" style="color: #009999;">9</span><span class="p">:])</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="266" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC266" class="line" lang="python">                <span class="k" style="font-weight: 600;">if</span> <span class="nf" style="color: #990000; font-weight: 600;">len</span><span class="p">(</span><span class="n" style="color: #333333;">calls</span><span class="p">)</span><span class="o" style="font-weight: 600;">!=</span><span class="n" style="color: #333333;">nsamp</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="252" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="267" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

267

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC267" class="line" lang="python">                    <span class="k" style="font-weight: 600;">raise</span> <span class="nc" style="color: #445588; font-weight: 600;">TreeTimeError</span><span class="p">(</span><span class="sa">f</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">Malformed VCF file </span><span class="si" style="color: #dd1144;">{</span><span class="n" style="color: #333333;">vcf_file</span><span class="si" style="color: #dd1144;">!r}</span><span class="s" style="color: #dd1144;"> - the data lines have different number of calls than the number of samples defined in the header</span><span class="sh" style="color: #dd1144;">"</span><span class="p">)</span></span>

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<td class="new_line diff-line-num new" data-linenumber="268" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC268" class="line" lang="python"></span>

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<td class="old_line diff-line-num new" data-linenumber="252" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="269" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC269" class="line" lang="python">                <span class="c1" style="color: #999988; font-style: italic;"># Treetime only parses GT FORMAT calls. Moreover, "the first sub-field must always be the genotype (GT) if it is present"</span></span>

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<td class="new_line diff-line-num new" data-linenumber="270" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC270" class="line" lang="python">                <span class="c1" style="color: #999988; font-style: italic;"># according to the VCF 4.2 spec. Note that if the VCF is for one sample only then the format's a bit different, but this'll</span></span>

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<td class="old_line diff-line-num new" data-linenumber="252" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="271" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

271

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC271" class="line" lang="python">                <span class="c1" style="color: #999988; font-style: italic;"># raise an error above because the header differs from what we assert. Other variation (CN, BND etc) is not parsed by</span></span>

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<td class="new_line diff-line-num new" data-linenumber="272" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC272" class="line" lang="python">                <span class="c1" style="color: #999988; font-style: italic;"># TreeTime, only GT.</span></span>

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<td class="old_line diff-line-num new" data-linenumber="252" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="273" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC273" class="line" lang="python">                <span class="n" style="color: #333333;">FORMAT</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">dat</span><span class="p">[</span><span class="mi" style="color: #009999;">8</span><span class="p">]</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="252" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="274" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC274" class="line" lang="python">                <span class="k" style="font-weight: 600;">if</span> <span class="ow" style="font-weight: 600;">not</span> <span class="n" style="color: #333333;">FORMAT</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">startswith</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">GT</span><span class="sh" style="color: #dd1144;">'</span><span class="p">):</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="252" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="275" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

275

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC275" class="line" lang="python">                    <span class="k" style="font-weight: 600;">continue</span></span>

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252

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<td class="new_line diff-line-num" data-linenumber="276" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC276" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="253" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="new_line diff-line-num old" data-linenumber="277" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC253" class="line" lang="python">            <span class="c1" style="color: #999988; font-style: italic;">#else you are a comment line, ignore.</span></span>

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<td class="old_line diff-line-num new" data-linenumber="254" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="277" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC277" class="line" lang="python">                <span class="c1" style="color: #999988; font-style: italic;">#get samples that differ from Ref at this site</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="254" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="278" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC278" class="line" lang="python">                <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">sname</span><span class="p">,</span> <span class="n" style="color: #333333;">sa</span> <span class="ow" style="font-weight: 600;">in</span> <span class="nf" style="color: #990000; font-weight: 600;">zip</span><span class="p">(</span><span class="n" style="color: #333333;">samps</span><span class="p">,</span> <span class="n" style="color: #333333;">calls</span><span class="p">):</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="279" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

279

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC279" class="line" lang="python">                    <span class="n" style="color: #333333;">gt</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">sa</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">split</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">:</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)[</span><span class="mi" style="color: #009999;">0</span><span class="p">]</span> <span class="c1" style="color: #999988; font-style: italic;"># May be multiple colon-separated subfields, depending on the line's FORMAT</span></span>

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<td class="new_line diff-line-num new" data-linenumber="280" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

280

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC280" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="254" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="281" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

281

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC281" class="line" lang="python">                    <span class="c1" style="color: #999988; font-style: italic;"># `gt` is the "index" of the alternate allele for this sample.</span></span>

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<td class="old_line diff-line-num new" data-linenumber="254" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="282" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC282" class="line" lang="python">                    <span class="c1" style="color: #999988; font-style: italic;"># The format of `gt` is quite varied:</span></span>

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<td class="old_line diff-line-num new" data-linenumber="254" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="283" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC283" class="line" lang="python">                    <span class="c1" style="color: #999988; font-style: italic;"># For haploid genomes, it's simply a single int _or_ "." (meaning a call cannot be made at the locus)</span></span>

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<td class="old_line diff-line-num new" data-linenumber="254" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="284" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

284

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC284" class="line" lang="python">                    <span class="c1" style="color: #999988; font-style: italic;"># For polyploid genomes, the format is a list of {int, '.'} separated by "/" or "|"</span></span>

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<td class="old_line diff-line-num new" data-linenumber="254" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="285" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC285" class="line" lang="python">                    <span class="c1" style="color: #999988; font-style: italic;"># ('/' means unphased, '|' means phased). </span></span>

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<td class="old_line diff-line-num new" data-linenumber="254" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="286" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC286" class="line" lang="python">                    <span class="c1" style="color: #999988; font-style: italic;"># If the index is an int, it's the 1-based (!) lookup index for ALT</span></span>

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<td class="new_line diff-line-num new" data-linenumber="287" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

287

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC287" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="254" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="288" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

288

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC288" class="line" lang="python">                    <span class="c1" style="color: #999988; font-style: italic;"># Split on the valid separators - if haploid, then we'll get a list len=1</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="254" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="289" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC289" class="line" lang="python">                    <span class="n" style="color: #333333;">gts</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">gt</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">split</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">|</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span> <span class="k" style="font-weight: 600;">if</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">|</span><span class="sh" style="color: #dd1144;">'</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">gt</span> <span class="k" style="font-weight: 600;">else</span> <span class="n" style="color: #333333;">gt</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">split</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">/</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="290" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

290

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC290" class="line" lang="python">                    <span class="n" style="color: #333333;">ploidy</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">len</span><span class="p">(</span><span class="n" style="color: #333333;">gts</span><span class="p">)</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="291" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

291

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC291" class="line" lang="python">                    <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">metadata</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">ploidy</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span> <span class="ow" style="font-weight: 600;">is</span> <span class="bp" style="color: #999999;">None</span><span class="p">:</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="292" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC292" class="line" lang="python">                        <span class="n" style="color: #333333;">metadata</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">ploidy</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">ploidy</span></span>

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<td class="old_line diff-line-num new" data-linenumber="254" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="293" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

293

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC293" class="line" lang="python">                    <span class="k" style="font-weight: 600;">elif</span> <span class="n" style="color: #333333;">metadata</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">ploidy</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span><span class="o" style="font-weight: 600;">!=</span><span class="n" style="color: #333333;">ploidy</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="254" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="294" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

294

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC294" class="line" lang="python">                        <span class="k" style="font-weight: 600;">raise</span> <span class="nc" style="color: #445588; font-weight: 600;">TreeTimeError</span><span class="p">(</span><span class="sa">f</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">The VCF file </span><span class="si" style="color: #dd1144;">{</span><span class="n" style="color: #333333;">vcf_file</span><span class="si" style="color: #dd1144;">!r}</span><span class="s" style="color: #dd1144;"> had genotype calls of ploidy </span><span class="si" style="color: #dd1144;">{</span><span class="n" style="color: #333333;">metadata</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">ploidy</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span><span class="si" style="color: #dd1144;">}</span><span class="s" style="color: #dd1144;"> but sample </span><span class="si" style="color: #dd1144;">{</span><span class="n" style="color: #333333;">sname</span><span class="si" style="color: #dd1144;">!r}</span><span class="s" style="color: #dd1144;"> has a genotype of ploidy </span><span class="si" style="color: #dd1144;">{</span><span class="n" style="color: #333333;">ploidy</span><span class="si" style="color: #dd1144;">}</span><span class="sh" style="color: #dd1144;">"</span><span class="p">)</span></span>

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<td class="new_line diff-line-num new" data-linenumber="295" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

295

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC295" class="line" lang="python"></span>

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<td class="old_line diff-line-num new" data-linenumber="254" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="296" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

296

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC296" class="line" lang="python">                    <span class="c1" style="color: #999988; font-style: italic;"># if polyploid, but homozygous, then treat as if haploid</span></span>

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<td class="old_line diff-line-num new" data-linenumber="254" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="297" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

297

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC297" class="line" lang="python">                    <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">ploidy</span><span class="o" style="font-weight: 600;">></span><span class="mi" style="color: #009999;">1</span> <span class="ow" style="font-weight: 600;">and</span> <span class="nf" style="color: #990000; font-weight: 600;">len</span><span class="p">(</span><span class="nf" style="color: #990000; font-weight: 600;">set</span><span class="p">(</span><span class="n" style="color: #333333;">gts</span><span class="p">))</span><span class="o" style="font-weight: 600;">==</span><span class="mi" style="color: #009999;">1</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="254" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="298" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

298

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC298" class="line" lang="python">                        <span class="n" style="color: #333333;">gt</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">gts</span><span class="p">[</span><span class="mi" style="color: #009999;">0</span><span class="p">]</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="254" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="299" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

299

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC299" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="254" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="300" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

300

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC300" class="line" lang="python">                    <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">gt</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">isdigit</span><span class="p">():</span> <span class="c1" style="color: #999988; font-style: italic;"># haploid, and a call has been made (i.e. it's not gt='.')</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="301" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

301

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC301" class="line" lang="python">                        <span class="n" style="color: #333333;">gt</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">int</span><span class="p">(</span><span class="n" style="color: #333333;">gt</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="254" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="302" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

302

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC302" class="line" lang="python">                        <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">gt</span><span class="o" style="font-weight: 600;">==</span><span class="mi" style="color: #009999;">0</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="254" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="303" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

303

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC303" class="line" lang="python">                            <span class="k" style="font-weight: 600;">continue</span> <span class="c1" style="color: #999988; font-style: italic;"># reference allele!</span></span>

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<td class="new_line diff-line-num new" data-linenumber="304" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

304

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC304" class="line" lang="python">                        <span class="n" style="color: #333333;">alt</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">validate_alt</span><span class="p">(</span><span class="n" style="color: #333333;">ALT</span><span class="p">[</span><span class="n" style="color: #333333;">gt</span><span class="o" style="font-weight: 600;">-</span><span class="mi" style="color: #009999;">1</span><span class="p">])</span> <span class="c1" style="color: #999988; font-style: italic;"># gt is the 1-based lookup, but ALT is 0-indexed</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="305" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC305" class="line" lang="python">                        <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">alt</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="254" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="306" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

306

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC306" class="line" lang="python">                            <span class="nf" style="color: #990000; font-weight: 600;">parse_homozygous_call</span><span class="p">(</span><span class="n" style="color: #333333;">sequences</span><span class="p">[</span><span class="n" style="color: #333333;">sname</span><span class="p">],</span><span class="n" style="color: #333333;">insertions</span><span class="p">[</span><span class="n" style="color: #333333;">sname</span><span class="p">],</span> <span class="n" style="color: #333333;">pos</span><span class="p">,</span> <span class="n" style="color: #333333;">REF</span><span class="p">,</span> <span class="n" style="color: #333333;">alt</span><span class="p">)</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="307" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

307

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC307" class="line" lang="python">                        <span class="k" style="font-weight: 600;">continue</span></span>

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<td class="old_line diff-line-num new" data-linenumber="254" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="308" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

308

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC308" class="line" lang="python"></span>

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<td class="old_line diff-line-num new" data-linenumber="254" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="309" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

309

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC309" class="line" lang="python">                    <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">gt</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="c1" style="color: #999988; font-style: italic;"># haploid "call cannot be made" identifier - replace REF with N(s)</span></span>

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<td class="old_line diff-line-num new" data-linenumber="254" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="310" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC310" class="line" lang="python">                        <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">i</span> <span class="ow" style="font-weight: 600;">in</span> <span class="nf" style="color: #990000; font-weight: 600;">range</span><span class="p">(</span><span class="nf" style="color: #990000; font-weight: 600;">len</span><span class="p">(</span><span class="n" style="color: #333333;">REF</span><span class="p">)):</span></span>

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<td class="old_line diff-line-num new" data-linenumber="254" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="311" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

311

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC311" class="line" lang="python">                            <span class="n" style="color: #333333;">sequences</span><span class="p">[</span><span class="n" style="color: #333333;">sname</span><span class="p">][</span><span class="n" style="color: #333333;">pos</span><span class="o" style="font-weight: 600;">+</span><span class="n" style="color: #333333;">i</span><span class="p">]</span> <span class="o" style="font-weight: 600;">=</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">N</span><span class="sh" style="color: #dd1144;">'</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="254" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="312" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

312

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC312" class="line" lang="python">                        <span class="k" style="font-weight: 600;">continue</span></span>

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<td class="old_line diff-line-num new" data-linenumber="254" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="313" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

313

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC313" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="254" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="314" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC314" class="line" lang="python">                    <span class="c1" style="color: #999988; font-style: italic;"># ---- heterozygous polyploid call  ----</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="315" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

315

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC315" class="line" lang="python">                    <span class="nf" style="color: #990000; font-weight: 600;">parse_heterozygous_call</span><span class="p">(</span><span class="n" style="color: #333333;">gt</span><span class="p">,</span> <span class="n" style="color: #333333;">sequences</span><span class="p">[</span><span class="n" style="color: #333333;">sname</span><span class="p">],</span><span class="n" style="color: #333333;">insertions</span><span class="p">[</span><span class="n" style="color: #333333;">sname</span><span class="p">],</span> <span class="n" style="color: #333333;">pos</span><span class="p">,</span> <span class="n" style="color: #333333;">REF</span><span class="p">,</span> <span class="n" style="color: #333333;">ALT</span><span class="p">)</span></span>

</pre></td>

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254

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<td class="new_line diff-line-num" data-linenumber="316" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC316" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="255" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

255

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<td class="new_line diff-line-num" data-linenumber="317" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC317" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">#Gather all variable positions</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="256" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="318" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC318" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">#NOTE: this does not consider positions of insertions</span></span>

</pre></td>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC319" class="line" lang="python">    <span class="n" style="color: #333333;">positions</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">set</span><span class="p">()</span></span>

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<td class="new_line diff-line-num" data-linenumber="320" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC320" class="line" lang="python">    <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">seq</span><span class="p">,</span> <span class="n" style="color: #333333;">muts</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">sequences</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">items</span><span class="p">():</span></span>

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<td class="old_line diff-line-num" data-linenumber="258" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="new_line diff-line-num" data-linenumber="321" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC321" class="line" lang="python">        <span class="n" style="color: #333333;">positions</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">update</span><span class="p">(</span><span class="n" style="color: #333333;">muts</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">keys</span><span class="p">())</span></span>

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<td class="new_line diff-line-num" data-linenumber="322" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC322" class="line" lang="python"></span>

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<td class="old_line diff-line-num new" data-linenumber="260" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="323" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC323" class="line" lang="python">    <span class="n" style="color: #333333;">num_insertions</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">sum</span><span class="p">([</span><span class="nf" style="color: #990000; font-weight: 600;">len</span><span class="p">(</span><span class="nf" style="color: #990000; font-weight: 600;">list</span><span class="p">(</span><span class="n" style="color: #333333;">ins</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">keys</span><span class="p">()))</span> <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">ins</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">insertions</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">values</span><span class="p">()])</span></span>

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<td class="old_line diff-line-num new" data-linenumber="260" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="324" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC324" class="line" lang="python">    <span class="k" style="font-weight: 600;">if</span> <span class="nf" style="color: #990000; font-weight: 600;">len</span><span class="p">(</span><span class="n" style="color: #333333;">positions</span><span class="p">)</span><span class="o" style="font-weight: 600;">==</span><span class="mi" style="color: #009999;">0</span> <span class="ow" style="font-weight: 600;">and</span> <span class="n" style="color: #333333;">num_insertions</span><span class="o" style="font-weight: 600;">==</span><span class="mi" style="color: #009999;">0</span><span class="p">:</span></span>

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<td class="old_line diff-line-num new" data-linenumber="260" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="325" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC325" class="line" lang="python">        <span class="k" style="font-weight: 600;">raise</span> <span class="nc" style="color: #445588; font-weight: 600;">TreeTimeError</span><span class="p">(</span><span class="sa">f</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">VCF file </span><span class="si" style="color: #dd1144;">{</span><span class="n" style="color: #333333;">vcf_file</span><span class="si" style="color: #dd1144;">!r}</span><span class="s" style="color: #dd1144;"> has no data-lines which we could extract genotype information from!</span><span class="sh" style="color: #dd1144;">"</span><span class="p">)</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC326" class="line" lang="python"></span>

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<td class="new_line diff-line-num" data-linenumber="327" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC327" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">#One or more seqs are same as ref! (No non-ref calls) So haven't been 'seen' yet</span></span>

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<td class="new_line diff-line-num" data-linenumber="328" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC328" class="line" lang="python">    <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">nsamp</span> <span class="o" style="font-weight: 600;">></span> <span class="nf" style="color: #990000; font-weight: 600;">len</span><span class="p">(</span><span class="n" style="color: #333333;">sequences</span><span class="p">):</span></span>

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<td class="new_line diff-line-num" data-linenumber="329" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC329" class="line" lang="python">        <span class="n" style="color: #333333;">missings</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">set</span><span class="p">(</span><span class="n" style="color: #333333;">samps</span><span class="p">).</span><span class="nf" style="color: #990000; font-weight: 600;">difference</span><span class="p">(</span><span class="n" style="color: #333333;">sequences</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">keys</span><span class="p">())</span></span>

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<td class="diff-line-num unfold js-unfold old_line" data-linenumber="273" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

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<td class="line_content match" style="color: rgba(5,5,6,.24); padding: inherit;" bgcolor="#fbfafd">@@ -273,12 +340,13 @@ def read_vcf(vcf_file, ref_file=None):</td>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC340" class="line" lang="python">    <span class="n" style="color: #333333;">compress_seq</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">{</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">reference</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span><span class="n" style="color: #333333;">refSeqStr</span><span class="p">,</span></span>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC341" class="line" lang="python">                    <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="n" style="color: #333333;">sequences</span><span class="p">,</span></span>

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<td class="new_line diff-line-num" data-linenumber="342" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC342" class="line" lang="python">                    <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">insertions</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="n" style="color: #333333;">insertions</span><span class="p">,</span></span>

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<td class="old_line diff-line-num old" data-linenumber="276" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="new_line diff-line-num old" data-linenumber="343" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC276" class="line" lang="python">                    <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">positions</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="nf" style="color: #990000; font-weight: 600;">sorted</span><span class="p">(</span><span class="n" style="color: #333333;">positions</span><span class="p">)}</span></span>

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC343" class="line" lang="python">                    <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">positions</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="nf" style="color: #990000; font-weight: 600;">sorted</span><span class="p">(</span><span class="n" style="color: #333333;">positions</span><span class="p">),</span></span>

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<td class="old_line diff-line-num new" data-linenumber="277" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC344" class="line" lang="python">                    <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">metadata</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span> <span class="n" style="color: #333333;">metadata</span><span class="p">}</span></span>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC345" class="line" lang="python"></span>

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<td class="old_line diff-line-num" data-linenumber="278" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="new_line diff-line-num" data-linenumber="346" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC346" class="line" lang="python">    <span class="k" style="font-weight: 600;">return</span> <span class="n" style="color: #333333;">compress_seq</span></span>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC347" class="line" lang="python"></span>

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<td class="new_line diff-line-num" data-linenumber="348" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC348" class="line" lang="python"></span>

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<td class="old_line diff-line-num old" data-linenumber="281" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="new_line diff-line-num old" data-linenumber="349" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC281" class="line" lang="python"><span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">write_vcf</span><span class="p">(</span><span class="n" style="color: #333333;">tree_dict</span><span class="p">,</span> <span class="n" style="color: #333333;">file_name</span><span class="p">):</span><span class="c1" style="color: #999988; font-style: italic;">#, compress=False):</span></span>

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<td class="old_line diff-line-num new" data-linenumber="282" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="349" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC349" class="line" lang="python"><span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">write_vcf</span><span class="p">(</span><span class="n" style="color: #333333;">tree_dict</span><span class="p">,</span> <span class="n" style="color: #333333;">file_name</span><span class="p"><span class="idiff left addition" style="background-color: #c7f0d2;">,</span></span><span class="idiff addition" style="background-color: #c7f0d2;"> </span><span class="n" style="color: #333333;"><span class="idiff addition" style="background-color: #c7f0d2;">mask</span></span><span class="o" style="font-weight: 600;"><span class="idiff addition" style="background-color: #c7f0d2;">=</span></span><span class="bp" style="color: #999999;"><span class="idiff right addition" style="background-color: #c7f0d2;">None</span></span><span class="p">):</span><span class="c1" style="color: #999988; font-style: italic;">#, compress=False):</span></span>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC350" class="line" lang="python">    <span class="sh" style="color: #dd1144;">"""</span></span>

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<td class="old_line diff-line-num" data-linenumber="283" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="new_line diff-line-num" data-linenumber="351" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC351" class="line" lang="python"><span class="s" style="color: #dd1144;">    Writes out a VCF-style file (which seems to be minimally handleable</span></span>

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<td class="old_line diff-line-num" data-linenumber="284" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="new_line diff-line-num" data-linenumber="352" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC352" class="line" lang="python"><span class="s" style="color: #dd1144;">    by vcftools and pyvcf) of the alignment. This is created from a dict</span></span>

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<td class="diff-line-num unfold js-unfold old_line" data-linenumber="290" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="diff-line-num unfold js-unfold new_line" data-linenumber="358" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="line_content match" style="color: rgba(5,5,6,.24); padding: inherit;" bgcolor="#fbfafd">@@ -290,13 +358,25 @@ def write_vcf(tree_dict, file_name):#, compress=False):</td>

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<td class="new_line diff-line-num" data-linenumber="358" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC358" class="line" lang="python"><span class="s" style="color: #dd1144;">    Parameters</span></span>

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<td class="old_line diff-line-num" data-linenumber="291" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

291

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<td class="new_line diff-line-num" data-linenumber="359" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

359

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC359" class="line" lang="python"><span class="s" style="color: #dd1144;">    ----------</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="292" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

292

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<td class="new_line diff-line-num" data-linenumber="360" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC360" class="line" lang="python"><span class="s" style="color: #dd1144;">     tree_dict: nested dict</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="293" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

293

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<td class="new_line diff-line-num old" data-linenumber="361" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC293" class="line" lang="python"><span class="s" style="color: #dd1144;">        A nested dict with keys </span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequence</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;"> </span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">reference</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;"> and </span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">positions</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">,</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="294" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

294

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<td class="new_line diff-line-num old" data-linenumber="361" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC294" class="line" lang="python"><span class="s" style="color: #dd1144;">        as is created by :py:meth:`treetime.TreeAnc.get_tree_dict`</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="295" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="361" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

361

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC361" class="line" lang="python"><span class="s" style="color: #dd1144;">        A nested dict with required keys of:</span></span>

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<td class="old_line diff-line-num new" data-linenumber="295" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="362" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

362

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC362" class="line" lang="python"><span class="s" style="color: #dd1144;">        </span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">: maps sampleName -> pos (0-based) -> new base (SNP)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="295" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="363" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

363

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC363" class="line" lang="python"><span class="s" style="color: #dd1144;">        </span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">reference</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">: string of reference nuc sequence</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="295" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="364" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC364" class="line" lang="python"><span class="s" style="color: #dd1144;">        </span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">positions</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">: sorted list of 0-based positions with variation in sequences</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="295" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="365" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

365

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC365" class="line" lang="python"><span class="s" style="color: #dd1144;">        And optional keys:</span></span>

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<td class="old_line diff-line-num new" data-linenumber="295" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="366" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

366

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC366" class="line" lang="python"><span class="s" style="color: #dd1144;">        </span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">inferred_const_sites</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">: list or set, 0-based positions to skip output for.</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="295" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="367" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

367

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC367" class="line" lang="python"><span class="s" style="color: #dd1144;">        This input is often created by :py:meth:`treetime.TreeAnc.get_tree_dict`</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="368" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

368

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC368" class="line" lang="python"><span class="s" style="color: #dd1144;">        </span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">metadata</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">: dict of information to influence VCF formatting. Only</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="295" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="369" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

369

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC369" class="line" lang="python"><span class="s" style="color: #dd1144;">        the following keys are used:</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="370" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

370

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC370" class="line" lang="python"><span class="s" style="color: #dd1144;">        </span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">metadata.ploidy</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">: int. Influences how genotype calls are formatted. (default</span></span>

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<td class="old_line diff-line-num new" data-linenumber="295" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="371" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

371

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC371" class="line" lang="python"><span class="s" style="color: #dd1144;">        of 2 (diploid) used if not provided)</span></span>

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<td class="old_line diff-line-num new" data-linenumber="295" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="372" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

372

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC372" class="line" lang="python"><span class="s" style="color: #dd1144;">        </span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">metadata.chrom</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">: str. The chromosome name (default of </span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;"> used if not provided)</span></span>

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295

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<td class="new_line diff-line-num" data-linenumber="373" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC373" class="line" lang="python"></span>

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<td class="old_line diff-line-num" data-linenumber="296" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

296

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<td class="new_line diff-line-num" data-linenumber="374" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC374" class="line" lang="python"><span class="s" style="color: #dd1144;">     file_name: str</span></span>

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<td class="old_line diff-line-num" data-linenumber="297" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

297

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<td class="new_line diff-line-num" data-linenumber="375" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

375

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC375" class="line" lang="python"><span class="s" style="color: #dd1144;">        File to which the new VCF should be written out. File names ending with</span></span>

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<td class="old_line diff-line-num" data-linenumber="298" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

298

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<td class="new_line diff-line-num" data-linenumber="376" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

376

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC376" class="line" lang="python"><span class="s" style="color: #dd1144;">        </span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">.gz</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;"> will result in the VCF automatically being gzipped.</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="299" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

299

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<td class="new_line diff-line-num" data-linenumber="377" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC377" class="line" lang="python"></span>

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<td class="old_line diff-line-num new" data-linenumber="300" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="378" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

378

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC378" class="line" lang="python"><span class="s" style="color: #dd1144;">    mask : optional, str of 0 or 1</span></span>

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<td class="old_line diff-line-num new" data-linenumber="300" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="379" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

379

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC379" class="line" lang="python"><span class="s" style="color: #dd1144;">        Calls at these positions will be skipped</span></span>

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<td class="old_line diff-line-num" data-linenumber="300" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="new_line diff-line-num" data-linenumber="380" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC380" class="line" lang="python"><span class="s" style="color: #dd1144;">    </span><span class="sh" style="color: #dd1144;">"""</span></span>

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<td class="new_line diff-line-num" data-linenumber="381" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC381" class="line" lang="python"></span>

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<td class="old_line diff-line-num" data-linenumber="302" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="new_line diff-line-num" data-linenumber="382" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC382" class="line" lang="python"><span class="c1" style="color: #999988; font-style: italic;">#   Programming Logic Note:</span></span>

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<td class="diff-line-num unfold js-unfold old_line" data-linenumber="329" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="diff-line-num unfold js-unfold new_line" data-linenumber="409" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="line_content match" style="color: rgba(5,5,6,.24); padding: inherit;" bgcolor="#fbfafd">@@ -329,6 +409,23 @@ def write_vcf(tree_dict, file_name):#, compress=False):</td>

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<td class="new_line diff-line-num" data-linenumber="409" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC409" class="line" lang="python">    <span class="n" style="color: #333333;">sequences</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">tree_dict</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequences</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span></span>

</pre></td>

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<td class="new_line diff-line-num" data-linenumber="410" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC410" class="line" lang="python">    <span class="n" style="color: #333333;">ref</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">tree_dict</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">reference</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span></span>

</pre></td>

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331

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<td class="new_line diff-line-num" data-linenumber="411" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

411

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC411" class="line" lang="python">    <span class="n" style="color: #333333;">positions</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">tree_dict</span><span class="p">[</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">positions</span><span class="sh" style="color: #dd1144;">'</span><span class="p">]</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="332" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="412" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

412

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC412" class="line" lang="python">    <span class="n" style="color: #333333;">ploidy</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">tree_dict</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">get</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">metadata</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="p">{}).</span><span class="nf" style="color: #990000; font-weight: 600;">get</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">ploidy</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="mi" style="color: #009999;">2</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="332" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="413" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

413

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC413" class="line" lang="python">    <span class="n" style="color: #333333;">chrom_name</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">tree_dict</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">get</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">metadata</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="p">{}).</span><span class="nf" style="color: #990000; font-weight: 600;">get</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">chrom</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="332" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="414" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

414

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC414" class="line" lang="python">    <span class="n" style="color: #333333;">sample_names</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">list</span><span class="p">(</span><span class="n" style="color: #333333;">sequences</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">keys</span><span class="p">())</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="332" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="415" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

415

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC415" class="line" lang="python">    <span class="n" style="color: #333333;">inferred_const_sites</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">set</span><span class="p">(</span><span class="n" style="color: #333333;">tree_dict</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">get</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">inferred_const_sites</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="p">[]))</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="416" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

416

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC416" class="line" lang="python"></span>

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<td class="old_line diff-line-num new" data-linenumber="332" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="417" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

417

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC417" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;"># For every variable site in sequences, flip the format around so</span></span>

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<td class="old_line diff-line-num new" data-linenumber="332" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="418" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

418

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC418" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;"># we can have fast lookups later on.</span></span>

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<td class="old_line diff-line-num new" data-linenumber="332" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="419" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

419

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC419" class="line" lang="python">    <span class="n" style="color: #333333;">alleles</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">{}</span></span>

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<td class="new_line diff-line-num new" data-linenumber="420" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

420

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC420" class="line" lang="python">    <span class="n" style="color: #333333;">num_samples</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">len</span><span class="p">(</span><span class="n" style="color: #333333;">sample_names</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="332" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="421" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

421

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC421" class="line" lang="python">    <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">idx</span><span class="p">,</span> <span class="n" style="color: #333333;">name</span> <span class="ow" style="font-weight: 600;">in</span> <span class="nf" style="color: #990000; font-weight: 600;">enumerate</span><span class="p">(</span><span class="n" style="color: #333333;">sample_names</span><span class="p">):</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="332" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="422" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

422

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC422" class="line" lang="python">        <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">posn</span><span class="p">,</span> <span class="n" style="color: #333333;">allele</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">sequences</span><span class="p">[</span><span class="n" style="color: #333333;">name</span><span class="p">].</span><span class="nf" style="color: #990000; font-weight: 600;">items</span><span class="p">():</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="423" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC423" class="line" lang="python">            <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">posn</span> <span class="ow" style="font-weight: 600;">not</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">alleles</span><span class="p">:</span></span>

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<td class="old_line diff-line-num new" data-linenumber="332" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="424" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC424" class="line" lang="python">                <span class="n" style="color: #333333;">alleles</span><span class="p">[</span><span class="n" style="color: #333333;">posn</span><span class="p">]</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">np</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">zeros</span><span class="p">(</span><span class="n" style="color: #333333;">num_samples</span><span class="p">,</span> <span class="n" style="color: #333333;">dtype</span><span class="o" style="font-weight: 600;">=</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">U</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

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<td class="old_line diff-line-num new" data-linenumber="332" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="425" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

425

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC425" class="line" lang="python">            <span class="n" style="color: #333333;">alleles</span><span class="p">[</span><span class="n" style="color: #333333;">posn</span><span class="p">][</span><span class="n" style="color: #333333;">idx</span><span class="p">]</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">allele</span></span>

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<td class="old_line diff-line-num new" data-linenumber="332" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="426" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC426" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;"># fill in reference</span></span>

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<td class="old_line diff-line-num new" data-linenumber="332" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="427" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC427" class="line" lang="python">    <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">posn</span><span class="p">,</span><span class="n" style="color: #333333;">bases</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">alleles</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">items</span><span class="p">():</span></span>

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<td class="old_line diff-line-num new" data-linenumber="332" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="428" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC428" class="line" lang="python">        <span class="n" style="color: #333333;">bases</span><span class="p">[</span><span class="n" style="color: #333333;">bases</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">''</span><span class="p">]</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">ref</span><span class="p">[</span><span class="n" style="color: #333333;">posn</span><span class="p">]</span></span>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC429" class="line" lang="python"></span>

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<td class="new_line diff-line-num" data-linenumber="430" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC430" class="line" lang="python">    <span class="k" style="font-weight: 600;">def</span> <span class="nf" style="color: #990000; font-weight: 600;">handleDeletions</span><span class="p">(</span><span class="n" style="color: #333333;">i</span><span class="p">,</span> <span class="n" style="color: #333333;">pi</span><span class="p">,</span> <span class="n" style="color: #333333;">pos</span><span class="p">,</span> <span class="n" style="color: #333333;">ref</span><span class="p">,</span> <span class="n" style="color: #333333;">delete</span><span class="p">,</span> <span class="n" style="color: #333333;">pattern</span><span class="p">):</span></span>

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<td class="new_line diff-line-num" data-linenumber="431" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC431" class="line" lang="python">        <span class="n" style="color: #333333;">refb</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">ref</span><span class="p">[</span><span class="n" style="color: #333333;">pi</span><span class="p">]</span></span>

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<td class="diff-line-num unfold js-unfold old_line" data-linenumber="371" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="diff-line-num unfold js-unfold new_line" data-linenumber="468" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="line_content match" style="color: rgba(5,5,6,.24); padding: inherit;" bgcolor="#fbfafd">@@ -371,7 +468,7 @@ def write_vcf(tree_dict, file_name):#, compress=False):</td>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC468" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#Rotate them into 'calls'</span></span>

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<td class="new_line diff-line-num" data-linenumber="469" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC469" class="line" lang="python">        <span class="n" style="color: #333333;">align</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">np</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">asarray</span><span class="p">(</span><span class="n" style="color: #333333;">sites</span><span class="p">).</span><span class="n" style="color: #333333;">T</span></span>

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC470" class="line" lang="python"></span>

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<td class="old_line diff-line-num old" data-linenumber="374" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="new_line diff-line-num old" data-linenumber="471" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC374" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#Get rid of '-', and put '<span class="idiff left right deletion" style="background-color: #fac5cd;">.</span>' for calls that match ref</span></span>

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<td class="new_line diff-line-num new" data-linenumber="471" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

471

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC471" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#Get rid of '-', and put '<span class="idiff left right addition" style="background-color: #c7f0d2;">0</span>' for calls that match ref</span></span>

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375

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<td class="new_line diff-line-num" data-linenumber="472" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

472

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC472" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#Only removes trailing '-'. This breaks VCF convension, but the standard</span></span>

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<td class="old_line diff-line-num" data-linenumber="376" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

376

</td>

<td class="new_line diff-line-num" data-linenumber="473" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

473

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC473" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#VCF way of handling this* is really complicated, and the situation is rare.</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="377" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

377

</td>

<td class="new_line diff-line-num" data-linenumber="474" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

474

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC474" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#(*deletions and mutations at the same locations)</span></span>

</pre></td>

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<td class="diff-line-num unfold js-unfold old_line" data-linenumber="383" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="diff-line-num unfold js-unfold new_line" data-linenumber="480" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="line_content match" style="color: rgba(5,5,6,.24); padding: inherit;" bgcolor="#fbfafd">@@ -383,7 +480,7 @@ def write_vcf(tree_dict, file_name):#, compress=False):</td>

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383

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<td class="new_line diff-line-num" data-linenumber="480" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

480

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC480" class="line" lang="python">                <span class="n" style="color: #333333;">gp</span><span class="o" style="font-weight: 600;">-=</span><span class="mi" style="color: #009999;">1</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="384" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

384

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<td class="new_line diff-line-num" data-linenumber="481" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

481

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC481" class="line" lang="python">            <span class="n" style="color: #333333;">pat</span> <span class="o" style="font-weight: 600;">=</span> <span class="sh" style="color: #dd1144;">""</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">join</span><span class="p">(</span><span class="n" style="color: #333333;">pt</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="385" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

385

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<td class="new_line diff-line-num" data-linenumber="482" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

482

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC482" class="line" lang="python">            <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">pat</span> <span class="o" style="font-weight: 600;">==</span> <span class="n" style="color: #333333;">refb</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="386" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

386

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<td class="new_line diff-line-num old" data-linenumber="483" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC386" class="line" lang="python">                <span class="n" style="color: #333333;">fullpat</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">append</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;"><span class="idiff left right deletion" style="background-color: #fac5cd;">.</span></span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="387" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="483" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

483

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC483" class="line" lang="python">                <span class="n" style="color: #333333;">fullpat</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">append</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;"><span class="idiff left right addition" style="background-color: #c7f0d2;">0</span></span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="387" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

387

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<td class="new_line diff-line-num" data-linenumber="484" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

484

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC484" class="line" lang="python">            <span class="k" style="font-weight: 600;">else</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="388" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

388

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<td class="new_line diff-line-num" data-linenumber="485" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

485

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC485" class="line" lang="python">                <span class="n" style="color: #333333;">fullpat</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">append</span><span class="p">(</span><span class="n" style="color: #333333;">pat</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="389" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

389

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<td class="new_line diff-line-num" data-linenumber="486" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

486

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC486" class="line" lang="python"></span>

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<td class="diff-line-num unfold js-unfold old_line" data-linenumber="393" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="diff-line-num unfold js-unfold new_line" data-linenumber="490" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="line_content match" style="color: rgba(5,5,6,.24); padding: inherit;" bgcolor="#fbfafd">@@ -393,19 +490,21 @@ def write_vcf(tree_dict, file_name):#, compress=False):</td>

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393

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490

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC490" class="line" lang="python"></span>

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394

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491

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC491" class="line" lang="python"></span>

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<td class="old_line diff-line-num" data-linenumber="395" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

395

</td>

<td class="new_line diff-line-num" data-linenumber="492" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

492

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC492" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">#prepare the header of the VCF & write out</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="396" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

396

</td>

<td class="new_line diff-line-num old" data-linenumber="493" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC396" class="line" lang="python">    <span class="n" style="color: #333333;">header</span><span class="o" style="font-weight: 600;">=</span><span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">#CHROM</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">POS</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">ID</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">REF</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">ALT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">QUAL</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">FILTER</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">INFO</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">FORMAT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">]</span><span class="o" style="font-weight: 600;">+</span><span class="nf" style="color: #990000; font-weight: 600;"><span class="idiff left deletion" style="background-color: #fac5cd;">list</span></span><span class="p"><span class="idiff deletion" style="background-color: #fac5cd;">(</span></span><span class="n" style="color: #333333;"><span class="idiff deletion" style="background-color: #fac5cd;">sequences</span></span><span class="p"><span class="idiff deletion" style="background-color: #fac5cd;">.</span></span><span class="nf" style="color: #990000; font-weight: 600;"><span class="idiff deletion" style="background-color: #fac5cd;">keys</span></span><span class="p"><span class="idiff right deletion" style="background-color: #fac5cd;">())</span></span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="397" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="493" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

493

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC493" class="line" lang="python">    <span class="n" style="color: #333333;">header</span><span class="o" style="font-weight: 600;">=</span><span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">#CHROM</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">POS</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">ID</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">REF</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">ALT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">QUAL</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">FILTER</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">INFO</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">FORMAT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">]</span><span class="o" style="font-weight: 600;">+</span><span class="n" style="color: #333333;"><span class="idiff left right addition" style="background-color: #c7f0d2;">sample_names</span></span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="397" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

397

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<td class="new_line diff-line-num" data-linenumber="494" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

494

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC494" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="398" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

398

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<td class="new_line diff-line-num" data-linenumber="495" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

495

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC495" class="line" lang="python">    <span class="n" style="color: #333333;">opn</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">gzip</span><span class="p">.</span><span class="nb" style="color: #0086b3;">open</span> <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">file_name</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">endswith</span><span class="p">((</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">.gz</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">.GZ</span><span class="sh" style="color: #dd1144;">'</span><span class="p">))</span> <span class="k" style="font-weight: 600;">else</span> <span class="nb" style="color: #0086b3;">open</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="399" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

399

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<td class="new_line diff-line-num" data-linenumber="496" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

496

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC496" class="line" lang="python">    <span class="n" style="color: #333333;">out_file</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">opn</span><span class="p">(</span><span class="n" style="color: #333333;">file_name</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">w</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="400" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

400

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<td class="new_line diff-line-num" data-linenumber="497" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

497

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC497" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="401" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

401

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<td class="new_line diff-line-num" data-linenumber="498" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

498

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC498" class="line" lang="python">    <span class="n" style="color: #333333;">out_file</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">write</span><span class="p">(</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">##fileformat=VCFv4.2</span><span class="se" style="color: #dd1144;">\n</span><span class="sh" style="color: #dd1144;">"</span><span class="o" style="font-weight: 600;">+</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="402" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

402

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<td class="new_line diff-line-num" data-linenumber="499" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

499

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC499" class="line" lang="python">                        <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">##source=NextStrain</span><span class="se" style="color: #dd1144;">\n</span><span class="sh" style="color: #dd1144;">"</span><span class="o" style="font-weight: 600;">+</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="403" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

403

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<td class="new_line diff-line-num old" data-linenumber="500" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC403" class="line" lang="python">                        <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">##FORMAT=<ID=GT,Number=1,Type=String,Description=</span><span class="se" style="color: #dd1144;">\"</span><span class="s" style="color: #dd1144;">Genotype</span><span class="se" style="color: #dd1144;">\"</span><span class="s" style="color: #dd1144;">></span><span class="se" style="color: #dd1144;">\n</span><span class="sh" style="color: #dd1144;">"</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="404" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="500" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

500

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC500" class="line" lang="python">                        <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">##FORMAT=<ID=GT,Number=1,Type=String,Description=</span><span class="se" style="color: #dd1144;">\"</span><span class="s" style="color: #dd1144;">Genotype</span><span class="se" style="color: #dd1144;">\"</span><span class="s" style="color: #dd1144;">></span><span class="se" style="color: #dd1144;">\n</span><span class="sh" style="color: #dd1144;">"</span><span class="o" style="font-weight: 600;">+</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="404" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="501" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

501

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC501" class="line" lang="python">                        <span class="sa">f</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">##contig=<ID=</span><span class="si" style="color: #dd1144;">{</span><span class="n" style="color: #333333;">chrom_name</span><span class="si" style="color: #dd1144;">}</span><span class="s" style="color: #dd1144;">></span><span class="se" style="color: #dd1144;">\n</span><span class="sh" style="color: #dd1144;">"</span><span class="p">)</span></span>

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<td class="old_line diff-line-num" data-linenumber="404" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

404

</td>

<td class="new_line diff-line-num" data-linenumber="502" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

502

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC502" class="line" lang="python">    <span class="n" style="color: #333333;">out_file</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">write</span><span class="p">(</span><span class="sh" style="color: #dd1144;">"</span><span class="se" style="color: #dd1144;">\t</span><span class="sh" style="color: #dd1144;">"</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">join</span><span class="p">(</span><span class="n" style="color: #333333;">header</span><span class="p">)</span><span class="o" style="font-weight: 600;">+</span><span class="sh" style="color: #dd1144;">"</span><span class="se" style="color: #dd1144;">\n</span><span class="sh" style="color: #dd1144;">"</span><span class="p">)</span></span>

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405

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<td class="new_line diff-line-num" data-linenumber="503" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

503

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC503" class="line" lang="python"></span>

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<td class="old_line diff-line-num" data-linenumber="406" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

406

</td>

<td class="new_line diff-line-num" data-linenumber="504" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

504

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC504" class="line" lang="python">    <span class="n" style="color: #333333;">vcfWrite</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">[]</span></span>

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<td class="old_line diff-line-num" data-linenumber="407" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

407

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<td class="new_line diff-line-num" data-linenumber="505" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

505

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC505" class="line" lang="python">    <span class="n" style="color: #333333;">errorPositions</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">[]</span></span>

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<td class="old_line diff-line-num" data-linenumber="408" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

408

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<td class="new_line diff-line-num" data-linenumber="506" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

506

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC506" class="line" lang="python">    <span class="n" style="color: #333333;">explainedErrors</span> <span class="o" style="font-weight: 600;">=</span> <span class="mi" style="color: #009999;">0</span></span>

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<td class="old_line diff-line-num new" data-linenumber="409" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="507" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

507

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC507" class="line" lang="python">    <span class="n" style="color: #333333;">mask_skip_count</span> <span class="o" style="font-weight: 600;">=</span> <span class="mi" style="color: #009999;">0</span></span>

</pre></td>

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409

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<td class="new_line diff-line-num" data-linenumber="508" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

508

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC508" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="410" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

410

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<td class="new_line diff-line-num" data-linenumber="509" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

509

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC509" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">#Why so basic? Because we sometimes have to back up a position!</span></span>

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411

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<td class="new_line diff-line-num" data-linenumber="510" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

510

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC510" class="line" lang="python">    <span class="n" style="color: #333333;">i</span><span class="o" style="font-weight: 600;">=</span><span class="mi" style="color: #009999;">0</span></span>

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<td class="diff-line-num unfold js-unfold old_line" data-linenumber="420" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="diff-line-num unfold js-unfold new_line" data-linenumber="519" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="line_content match" style="color: rgba(5,5,6,.24); padding: inherit;" bgcolor="#fbfafd">@@ -420,28 +519,14 @@ def write_vcf(tree_dict, file_name):#, compress=False):</td>

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420

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<td class="new_line diff-line-num" data-linenumber="519" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

519

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC519" class="line" lang="python">        <span class="n" style="color: #333333;">delete</span> <span class="o" style="font-weight: 600;">=</span> <span class="bp" style="color: #999999;">False</span> <span class="c1" style="color: #999988; font-style: italic;">#deletion at this position - need to grab previous base (invariable)</span></span>

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421

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<td class="new_line diff-line-num" data-linenumber="520" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

520

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC520" class="line" lang="python">        <span class="n" style="color: #333333;">deleteGroup</span> <span class="o" style="font-weight: 600;">=</span> <span class="bp" style="color: #999999;">False</span> <span class="c1" style="color: #999988; font-style: italic;">#deletion at next position (mutation at this pos) - do not need to get prev base</span></span>

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422

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521

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC521" class="line" lang="python"></span>

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423

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<td class="new_line diff-line-num old" data-linenumber="522" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC423" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#try/except is much more efficient than 'if' statements for constructing patterns,</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="424" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

424

</td>

<td class="new_line diff-line-num old" data-linenumber="522" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC424" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#as on average a 'variable' location will not be variable for any given sequence</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="425" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

425

</td>

<td class="new_line diff-line-num old" data-linenumber="522" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC425" class="line" lang="python">        <span class="n" style="color: #333333;">pattern</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">[]</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="426" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

426

</td>

<td class="new_line diff-line-num old" data-linenumber="522" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC426" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#pattern2 gets the pattern at next position to check for upcoming deletions</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="427" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

427

</td>

<td class="new_line diff-line-num old" data-linenumber="522" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC427" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#it's more efficient to get both here rather than loop through sequences twice!</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="428" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

428

</td>

<td class="new_line diff-line-num old" data-linenumber="522" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC428" class="line" lang="python">        <span class="n" style="color: #333333;">pattern2</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">[]</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="429" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

429

</td>

<td class="new_line diff-line-num old" data-linenumber="522" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC429" class="line" lang="python">        <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">k</span><span class="p">,</span><span class="n" style="color: #333333;">v</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">sequences</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">items</span><span class="p">():</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="430" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

430

</td>

<td class="new_line diff-line-num old" data-linenumber="522" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC430" class="line" lang="python">            <span class="k" style="font-weight: 600;">try</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="431" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

431

</td>

<td class="new_line diff-line-num old" data-linenumber="522" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC431" class="line" lang="python">                <span class="n" style="color: #333333;">pattern</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">append</span><span class="p">(</span><span class="n" style="color: #333333;">sequences</span><span class="p">[</span><span class="n" style="color: #333333;">k</span><span class="p">][</span><span class="n" style="color: #333333;">pi</span><span class="p">])</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="432" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

432

</td>

<td class="new_line diff-line-num old" data-linenumber="522" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC432" class="line" lang="python">            <span class="k" style="font-weight: 600;">except</span> <span class="nb" style="color: #0086b3;">KeyError</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="433" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

433

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<td class="new_line diff-line-num old" data-linenumber="522" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC433" class="line" lang="python">                <span class="n" style="color: #333333;">pattern</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">append</span><span class="p">(</span><span class="n" style="color: #333333;">ref</span><span class="p">[</span><span class="n" style="color: #333333;">pi</span><span class="p">])</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="434" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

434

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<td class="new_line diff-line-num old" data-linenumber="522" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC434" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="435" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

435

</td>

<td class="new_line diff-line-num old" data-linenumber="522" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC435" class="line" lang="python">            <span class="k" style="font-weight: 600;">try</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="436" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

436

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<td class="new_line diff-line-num old" data-linenumber="522" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC436" class="line" lang="python">                <span class="n" style="color: #333333;">pattern2</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">append</span><span class="p">(</span><span class="n" style="color: #333333;">sequences</span><span class="p">[</span><span class="n" style="color: #333333;">k</span><span class="p">][</span><span class="n" style="color: #333333;">pi</span><span class="o" style="font-weight: 600;">+</span><span class="mi" style="color: #009999;">1</span><span class="p">])</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="437" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

437

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<td class="new_line diff-line-num old" data-linenumber="522" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC437" class="line" lang="python">            <span class="k" style="font-weight: 600;">except</span> <span class="nb" style="color: #0086b3;">KeyError</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="438" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

438

</td>

<td class="new_line diff-line-num old" data-linenumber="522" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC438" class="line" lang="python">                <span class="k" style="font-weight: 600;">try</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="439" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

439

</td>

<td class="new_line diff-line-num old" data-linenumber="522" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC439" class="line" lang="python">                    <span class="n" style="color: #333333;">pattern2</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">append</span><span class="p">(</span><span class="n" style="color: #333333;">ref</span><span class="p">[</span><span class="n" style="color: #333333;">pi</span><span class="o" style="font-weight: 600;">+</span><span class="mi" style="color: #009999;">1</span><span class="p">])</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="440" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

440

</td>

<td class="new_line diff-line-num old" data-linenumber="522" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC440" class="line" lang="python">                <span class="k" style="font-weight: 600;">except</span> <span class="nb" style="color: #0086b3;">IndexError</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="441" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

441

</td>

<td class="new_line diff-line-num old" data-linenumber="522" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC441" class="line" lang="python">                    <span class="k" style="font-weight: 600;">pass</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="442" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="522" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

522

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC522" class="line" lang="python">        <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">mask</span> <span class="ow" style="font-weight: 600;">and</span> <span class="n" style="color: #333333;">mask</span><span class="p">[</span><span class="n" style="color: #333333;">pi</span><span class="p">]</span> <span class="o" style="font-weight: 600;">==</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">1</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="442" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="523" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

523

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC523" class="line" lang="python">            <span class="n" style="color: #333333;">mask_skip_count</span><span class="o" style="font-weight: 600;">+=</span><span class="mi" style="color: #009999;">1</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="442" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="524" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

524

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC524" class="line" lang="python">            <span class="n" style="color: #333333;">i</span><span class="o" style="font-weight: 600;">+=</span><span class="mi" style="color: #009999;">1</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="442" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="525" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

525

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC525" class="line" lang="python">            <span class="k" style="font-weight: 600;">continue</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="442" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

442

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<td class="new_line diff-line-num" data-linenumber="526" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

526

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC526" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="443" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

443

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<td class="new_line diff-line-num old" data-linenumber="527" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC443" class="line" lang="python">        <span class="n" style="color: #333333;">pattern</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">np</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">array</span><span class="p">(</span><span class="n" style="color: #333333;">pattern</span><span class="p">).</span><span class="nf" style="color: #990000; font-weight: 600;">astype</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">U</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="444" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

444

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<td class="new_line diff-line-num old" data-linenumber="527" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC444" class="line" lang="python">        <span class="n" style="color: #333333;">pattern2</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">np</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">array</span><span class="p">(</span><span class="n" style="color: #333333;">pattern2</span><span class="p">).</span><span class="nf" style="color: #990000; font-weight: 600;">astype</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">U</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="445" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="527" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

527

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC527" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;"># patterns will be empty if there was no variation in the sequences</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="528" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

528

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC528" class="line" lang="python">        <span class="n" style="color: #333333;">pattern</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">alleles</span><span class="p">[</span><span class="n" style="color: #333333;">pi</span><span class="p">]</span> <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">pi</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">alleles</span> <span class="k" style="font-weight: 600;">else</span> <span class="n" style="color: #333333;">np</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">array</span><span class="p">([]).</span><span class="nf" style="color: #990000; font-weight: 600;">astype</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">U</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

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<td class="new_line diff-line-num new" data-linenumber="529" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

529

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC529" class="line" lang="python">        <span class="n" style="color: #333333;">pattern2</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">alleles</span><span class="p">[</span><span class="n" style="color: #333333;">pi</span><span class="o" style="font-weight: 600;">+</span><span class="mi" style="color: #009999;">1</span><span class="p">]</span> <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">pi</span><span class="o" style="font-weight: 600;">+</span><span class="mi" style="color: #009999;">1</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">alleles</span> <span class="k" style="font-weight: 600;">else</span> <span class="n" style="color: #333333;">np</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">array</span><span class="p">([]).</span><span class="nf" style="color: #990000; font-weight: 600;">astype</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">U</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

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445

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530

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC530" class="line" lang="python"></span>

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<td class="old_line diff-line-num" data-linenumber="446" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

446

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<td class="new_line diff-line-num" data-linenumber="531" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

531

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC531" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#If a deletion here, need to gather up all bases, and position before</span></span>

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447

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<td class="new_line diff-line-num" data-linenumber="532" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

532

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC532" class="line" lang="python">        <span class="k" style="font-weight: 600;">if</span> <span class="nf" style="color: #990000; font-weight: 600;">any</span><span class="p">(</span><span class="n" style="color: #333333;">pattern</span> <span class="o" style="font-weight: 600;">==</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">-</span><span class="sh" style="color: #dd1144;">'</span><span class="p">):</span></span>

</pre></td>

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<td class="diff-line-num unfold js-unfold old_line" data-linenumber="462" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="diff-line-num unfold js-unfold new_line" data-linenumber="547" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="line_content match" style="color: rgba(5,5,6,.24); padding: inherit;" bgcolor="#fbfafd">@@ -462,39 +547,40 @@ def write_vcf(tree_dict, file_name):#, compress=False):</td>

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462

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547

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC547" class="line" lang="python"></span>

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<td class="old_line diff-line-num" data-linenumber="463" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

463

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<td class="new_line diff-line-num" data-linenumber="548" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

548

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC548" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#If deletion, treat affected bases as 1 'call':</span></span>

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464

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<td class="new_line diff-line-num" data-linenumber="549" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

549

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC549" class="line" lang="python">        <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">delete</span> <span class="ow" style="font-weight: 600;">or</span> <span class="n" style="color: #333333;">deleteGroup</span><span class="p">:</span></span>

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<td class="old_line diff-line-num new" data-linenumber="465" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="550" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

550

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC550" class="line" lang="python">            <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">pattern</span><span class="p">.</span><span class="n" style="color: #333333;">size</span><span class="o" style="font-weight: 600;">==</span><span class="mi" style="color: #009999;">0</span><span class="p">:</span> <span class="c1" style="color: #999988; font-style: italic;"># no variation in sequences</span></span>

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<td class="old_line diff-line-num new" data-linenumber="465" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="551" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

551

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC551" class="line" lang="python">                <span class="n" style="color: #333333;">pattern</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">np</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">full</span><span class="p">(</span><span class="n" style="color: #333333;">num_samples</span><span class="p">,</span> <span class="n" style="color: #333333;">refb</span><span class="p">,</span> <span class="n" style="color: #333333;">dtype</span><span class="o" style="font-weight: 600;">=</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">U</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

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465

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<td class="new_line diff-line-num" data-linenumber="552" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

552

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC552" class="line" lang="python">            <span class="n" style="color: #333333;">i</span><span class="p">,</span> <span class="n" style="color: #333333;">pi</span><span class="p">,</span> <span class="n" style="color: #333333;">pos</span><span class="p">,</span> <span class="n" style="color: #333333;">refb</span><span class="p">,</span> <span class="n" style="color: #333333;">pattern</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">handleDeletions</span><span class="p">(</span><span class="n" style="color: #333333;">i</span><span class="p">,</span> <span class="n" style="color: #333333;">pi</span><span class="p">,</span> <span class="n" style="color: #333333;">pos</span><span class="p">,</span> <span class="n" style="color: #333333;">ref</span><span class="p">,</span> <span class="n" style="color: #333333;">delete</span><span class="p">,</span> <span class="n" style="color: #333333;">pattern</span><span class="p">)</span></span>

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<td class="old_line diff-line-num old" data-linenumber="466" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

466

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<td class="new_line diff-line-num old" data-linenumber="553" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC466" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#If no deletion, replace ref with '<span class="idiff left right deletion" style="background-color: #fac5cd;">.', as in VCF format</span></span></span>

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<td class="new_line diff-line-num new" data-linenumber="553" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

553

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC553" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#If no deletion, replace ref with '<span class="idiff left right addition" style="background-color: #c7f0d2;">0' which means the reference base is unchanged</span></span></span>

</pre></td>

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467

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<td class="new_line diff-line-num" data-linenumber="554" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

554

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC554" class="line" lang="python">        <span class="k" style="font-weight: 600;">else</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="468" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

468

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<td class="new_line diff-line-num old" data-linenumber="555" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC468" class="line" lang="python">            <span class="n" style="color: #333333;">pattern</span><span class="p">[</span><span class="n" style="color: #333333;">pattern</span><span class="o" style="font-weight: 600;">==</span><span class="n" style="color: #333333;">refb</span><span class="p">]</span> <span class="o" style="font-weight: 600;">=</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;"><span class="idiff left right deletion" style="background-color: #fac5cd;">.</span></span><span class="sh" style="color: #dd1144;">'</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="469" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="555" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

555

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC555" class="line" lang="python">            <span class="n" style="color: #333333;">pattern</span><span class="p">[</span><span class="n" style="color: #333333;">pattern</span><span class="o" style="font-weight: 600;">==</span><span class="n" style="color: #333333;">refb</span><span class="p">]</span> <span class="o" style="font-weight: 600;">=</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;"><span class="idiff left right addition" style="background-color: #c7f0d2;">0</span></span><span class="sh" style="color: #dd1144;">'</span></span>

</pre></td>

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469

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<td class="new_line diff-line-num" data-linenumber="556" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

556

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC556" class="line" lang="python"></span>

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<td class="old_line diff-line-num old" data-linenumber="470" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

470

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<td class="new_line diff-line-num old" data-linenumber="557" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC470" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#Get the list of ALTs - minus any '<span class="idiff left right deletion" style="background-color: #fac5cd;">.'</span>!</span></span>

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<td class="old_line diff-line-num new" data-linenumber="471" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="557" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

557

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC557" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#Get the list of ALTs - minus any '<span class="idiff left right addition" style="background-color: #c7f0d2;">0' which are unchanged reference sequences</span>!</span></span>

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471

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<td class="new_line diff-line-num" data-linenumber="558" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

558

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC558" class="line" lang="python">        <span class="n" style="color: #333333;">uniques</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">np</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">unique</span><span class="p">(</span><span class="n" style="color: #333333;">pattern</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="472" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

472

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<td class="new_line diff-line-num old" data-linenumber="559" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC472" class="line" lang="python">        <span class="n" style="color: #333333;">uniques</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">uniques</span><span class="p">[</span><span class="n" style="color: #333333;">np</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">where</span><span class="p">(</span><span class="n" style="color: #333333;">uniques</span><span class="o" style="font-weight: 600;">!=</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;"><span class="idiff left right deletion" style="background-color: #fac5cd;">.</span></span><span class="sh" style="color: #dd1144;">'</span><span class="p">)]</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="473" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="559" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

559

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC559" class="line" lang="python">        <span class="n" style="color: #333333;">uniques</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">uniques</span><span class="p">[</span><span class="n" style="color: #333333;">np</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">where</span><span class="p">(</span><span class="n" style="color: #333333;">uniques</span><span class="o" style="font-weight: 600;">!=</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;"><span class="idiff left right addition" style="background-color: #c7f0d2;">0</span></span><span class="sh" style="color: #dd1144;">'</span><span class="p">)]</span></span>

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473

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<td class="new_line diff-line-num" data-linenumber="560" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

560

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC560" class="line" lang="python"></span>

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<td class="old_line diff-line-num" data-linenumber="474" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

474

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<td class="new_line diff-line-num" data-linenumber="561" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

561

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC561" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#Convert bases to the number that matches the ALT</span></span>

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<td class="old_line diff-line-num" data-linenumber="475" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

475

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<td class="new_line diff-line-num" data-linenumber="562" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

562

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC562" class="line" lang="python">        <span class="n" style="color: #333333;">j</span><span class="o" style="font-weight: 600;">=</span><span class="mi" style="color: #009999;">1</span></span>

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476

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563

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC563" class="line" lang="python">        <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">u</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">uniques</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="477" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

477

</td>

<td class="new_line diff-line-num" data-linenumber="564" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

564

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC564" class="line" lang="python">            <span class="n" style="color: #333333;">pattern</span><span class="p">[</span><span class="n" style="color: #333333;">np</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">where</span><span class="p">(</span><span class="n" style="color: #333333;">pattern</span><span class="o" style="font-weight: 600;">==</span><span class="n" style="color: #333333;">u</span><span class="p">)[</span><span class="mi" style="color: #009999;">0</span><span class="p">]]</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">str</span><span class="p">(</span><span class="n" style="color: #333333;">j</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="478" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

478

</td>

<td class="new_line diff-line-num" data-linenumber="565" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

565

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC565" class="line" lang="python">            <span class="n" style="color: #333333;">j</span><span class="o" style="font-weight: 600;">+=</span><span class="mi" style="color: #009999;">1</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="479" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

479

</td>

<td class="new_line diff-line-num old" data-linenumber="566" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC479" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#Now convert these calls to #/# (VCF format)</span></span>

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<td class="old_line diff-line-num old" data-linenumber="480" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

480

</td>

<td class="new_line diff-line-num old" data-linenumber="566" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC480" class="line" lang="python">        <span class="n" style="color: #333333;">calls</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">[</span> <span class="n" style="color: #333333;">j</span><span class="o" style="font-weight: 600;">+</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">/</span><span class="sh" style="color: #dd1144;">"</span><span class="o" style="font-weight: 600;">+</span><span class="n" style="color: #333333;">j</span> <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">j</span><span class="o" style="font-weight: 600;">!=</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">'</span> <span class="k" style="font-weight: 600;">else</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">'</span> <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">j</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">pattern</span> <span class="p">]</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="481" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

481

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<td class="new_line diff-line-num" data-linenumber="566" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

566

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC566" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="482" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

482

</td>

<td class="new_line diff-line-num" data-linenumber="567" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

567

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC567" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#What if there's no variation at a variable site??</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="483" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

483

</td>

<td class="new_line diff-line-num" data-linenumber="568" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

568

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC568" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#This can happen when sites are modified by TreeTime - see below.</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="484" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

484

</td>

<td class="new_line diff-line-num old" data-linenumber="569" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC484" class="line" lang="python">        <span class="n" style="color: #333333;">printPos</span> <span class="o" style="font-weight: 600;">=</span> <span class="bp" style="color: #999999;">True</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="485" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

485

</td>

<td class="new_line diff-line-num old" data-linenumber="569" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC485" class="line" lang="python">        <span class="k" style="font-weight: 600;">if</span> <span class="nf" style="color: #990000; font-weight: 600;">len</span><span class="p">(</span><span class="n" style="color: #333333;">uniques</span><span class="p">)</span><span class="o" style="font-weight: 600;">==</span><span class="mi" style="color: #009999;">0</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="486" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="569" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

569

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC569" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#We don't print to VCF (because no variation!)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="486" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="570" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

570

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC570" class="line" lang="python">        <span class="n" style="color: #333333;">any_variation</span> <span class="o" style="font-weight: 600;">=</span> <span class="nf" style="color: #990000; font-weight: 600;">len</span><span class="p">(</span><span class="n" style="color: #333333;">uniques</span><span class="p">)</span><span class="o" style="font-weight: 600;">!=</span><span class="mi" style="color: #009999;">0</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="486" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="571" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

571

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC571" class="line" lang="python">        <span class="k" style="font-weight: 600;">if</span> <span class="ow" style="font-weight: 600;">not</span> <span class="n" style="color: #333333;">any_variation</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="486" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

486

</td>

<td class="new_line diff-line-num" data-linenumber="572" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

572

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC572" class="line" lang="python">            <span class="c1" style="color: #999988; font-style: italic;">#If we expect it (it was made constant by TreeTime), it's fine.</span></span>

</pre></td>

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487

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<td class="new_line diff-line-num old" data-linenumber="573" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC487" class="line" lang="python">            <span class="k" style="font-weight: 600;">if</span> <span class="sh" style="color: #dd1144;"><span class="idiff left deletion" style="background-color: #fac5cd;">'</span></span><span class="s" style="color: #dd1144;"><span class="idiff deletion" style="background-color: #fac5cd;">inferred_const_sites</span></span><span class="sh" style="color: #dd1144;"><span class="idiff deletion" style="background-color: #fac5cd;">'</span></span><span class="idiff deletion" style="background-color: #fac5cd;"> </span><span class="ow" style="font-weight: 600;"><span class="idiff deletion" style="background-color: #fac5cd;">in</span></span><span class="idiff deletion" style="background-color: #fac5cd;"> </span><span class="n" style="color: #333333;"><span class="idiff deletion" style="background-color: #fac5cd;">tree_dict</span></span><span class="idiff deletion" style="background-color: #fac5cd;"> </span><span class="ow" style="font-weight: 600;"><span class="idiff deletion" style="background-color: #fac5cd;">and</span></span><span class="idiff deletion" style="background-color: #fac5cd;"> </span><span class="n" style="color: #333333;"><span class="idiff deletion" style="background-color: #fac5cd;">pi</span></span><span class="idiff deletion" style="background-color: #fac5cd;"> </span><span class="ow" style="font-weight: 600;"><span class="idiff deletion" style="background-color: #fac5cd;">in</span></span><span class="idiff deletion" style="background-color: #fac5cd;"> </span><span class="n" style="color: #333333;"><span class="idiff deletion" style="background-color: #fac5cd;">tree_dict</span></span><span class="p"><span class="idiff deletion" style="background-color: #fac5cd;">[</span></span><span class="sh" style="color: #dd1144;"><span class="idiff deletion" style="background-color: #fac5cd;">'</span></span><span class="s" style="color: #dd1144;">inferred_const_sites</span><span class="sh" style="color: #dd1144;"><span class="idiff deletion" style="background-color: #fac5cd;">'</span></span><span class="p"><span class="idiff right deletion" style="background-color: #fac5cd;">]</span>:</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="488" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="573" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

573

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC573" class="line" lang="python">            <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;"><span class="idiff left addition" style="background-color: #c7f0d2;">pi</span></span><span class="idiff addition" style="background-color: #c7f0d2;"> </span><span class="ow" style="font-weight: 600;"><span class="idiff addition" style="background-color: #c7f0d2;">in</span></span><span class="idiff right addition" style="background-color: #c7f0d2;"> </span><span class="n" style="color: #333333;">inferred_const_sites</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="488" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

488

</td>

<td class="new_line diff-line-num" data-linenumber="574" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

574

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC574" class="line" lang="python">                <span class="n" style="color: #333333;">explainedErrors</span> <span class="o" style="font-weight: 600;">+=</span> <span class="mi" style="color: #009999;">1</span></span>

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<td class="old_line diff-line-num old" data-linenumber="489" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

489

</td>

<td class="new_line diff-line-num old" data-linenumber="575" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC489" class="line" lang="python">                <span class="n" style="color: #333333;">printPos</span> <span class="o" style="font-weight: 600;">=</span> <span class="bp" style="color: #999999;">False</span> <span class="c1" style="color: #999988; font-style: italic;">#and don't output position to the VCF</span></span>

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<td class="old_line diff-line-num" data-linenumber="490" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

490

</td>

<td class="new_line diff-line-num" data-linenumber="575" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

575

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC575" class="line" lang="python">            <span class="k" style="font-weight: 600;">else</span><span class="p">:</span></span>

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<td class="old_line diff-line-num" data-linenumber="491" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

491

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<td class="new_line diff-line-num" data-linenumber="576" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

576

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC576" class="line" lang="python">                <span class="c1" style="color: #999988; font-style: italic;">#If we don't expect, raise an error</span></span>

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<td class="old_line diff-line-num" data-linenumber="492" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

492

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<td class="new_line diff-line-num" data-linenumber="577" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

577

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC577" class="line" lang="python">                <span class="n" style="color: #333333;">errorPositions</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">append</span><span class="p">(</span><span class="nf" style="color: #990000; font-weight: 600;">str</span><span class="p">(</span><span class="n" style="color: #333333;">pi</span><span class="p">))</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="493" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

493

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<td class="new_line diff-line-num" data-linenumber="578" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

578

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC578" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="494" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

494

</td>

<td class="new_line diff-line-num" data-linenumber="579" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

579

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC579" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#Write it out - Increment positions by 1 so it's in VCF numbering</span></span>

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<td class="old_line diff-line-num" data-linenumber="495" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

495

</td>

<td class="new_line diff-line-num" data-linenumber="580" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

580

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC580" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;">#If no longer variable, and explained, don't write it out</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="496" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

496

</td>

<td class="new_line diff-line-num old" data-linenumber="581" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC496" class="line" lang="python">        <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">printPos</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="497" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

497

</td>

<td class="new_line diff-line-num old" data-linenumber="581" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC497" class="line" lang="python">            <span class="n" style="color: #333333;">output</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">[</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">MTB_anc</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="nf" style="color: #990000; font-weight: 600;">str</span><span class="p">(</span><span class="n" style="color: #333333;">pos</span><span class="p">),</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="n" style="color: #333333;">refb</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">,</span><span class="sh" style="color: #dd1144;">"</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">join</span><span class="p">(</span><span class="n" style="color: #333333;">uniques</span><span class="p">),</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">PASS</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">]</span> <span class="o" style="font-weight: 600;">+</span> <span class="n" style="color: #333333;">calls</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="498" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="581" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

581

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC581" class="line" lang="python">        <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">any_variation</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="498" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="582" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

582

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC582" class="line" lang="python">            <span class="n" style="color: #333333;">calls</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">[</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">/</span><span class="sh" style="color: #dd1144;">"</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">join</span><span class="p">([</span><span class="n" style="color: #333333;">j</span><span class="p">]</span><span class="o" style="font-weight: 600;">*</span><span class="n" style="color: #333333;">ploidy</span><span class="p">)</span> <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">j</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">pattern</span> <span class="p">]</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="498" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="583" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

583

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC583" class="line" lang="python">            <span class="n" style="color: #333333;">output</span> <span class="o" style="font-weight: 600;">=</span> <span class="p">[</span><span class="n" style="color: #333333;">chrom_name</span><span class="p">,</span> <span class="nf" style="color: #990000; font-weight: 600;">str</span><span class="p">(</span><span class="n" style="color: #333333;">pos</span><span class="p">),</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="n" style="color: #333333;">refb</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">,</span><span class="sh" style="color: #dd1144;">"</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">join</span><span class="p">(</span><span class="n" style="color: #333333;">uniques</span><span class="p">),</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">PASS</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">.</span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">GT</span><span class="sh" style="color: #dd1144;">"</span><span class="p">]</span> <span class="o" style="font-weight: 600;">+</span> <span class="n" style="color: #333333;">calls</span></span>

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<td class="old_line diff-line-num" data-linenumber="498" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

498

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<td class="new_line diff-line-num" data-linenumber="584" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

584

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC584" class="line" lang="python">            <span class="n" style="color: #333333;">vcfWrite</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">append</span><span class="p">(</span><span class="sh" style="color: #dd1144;">"</span><span class="se" style="color: #dd1144;">\t</span><span class="sh" style="color: #dd1144;">"</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">join</span><span class="p">(</span><span class="n" style="color: #333333;">output</span><span class="p">))</span></span>

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<td class="old_line diff-line-num" data-linenumber="499" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

499

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<td class="new_line diff-line-num" data-linenumber="585" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

585

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC585" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="500" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

500

</td>

<td class="new_line diff-line-num" data-linenumber="586" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

586

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC586" class="line" lang="python">        <span class="n" style="color: #333333;">i</span><span class="o" style="font-weight: 600;">+=</span><span class="mi" style="color: #009999;">1</span></span>

</pre></td>

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<td class="diff-line-num unfold js-unfold old_line" data-linenumber="507" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="diff-line-num unfold js-unfold new_line" data-linenumber="593" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">...</td>

<td class="line_content match" style="color: rgba(5,5,6,.24); padding: inherit;" bgcolor="#fbfafd">@@ -507,6 +593,9 @@ def write_vcf(tree_dict, file_name):#, compress=False):</td>

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507

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<td class="new_line diff-line-num" data-linenumber="593" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

593

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC593" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">#purposes, because the site is 'variant' against the ref, it is variant, as expected, and so</span></span>

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<td class="old_line diff-line-num" data-linenumber="508" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

508

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<td class="new_line diff-line-num" data-linenumber="594" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

594

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC594" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">#won't be counted in the below list, which is only sites removed from the VCF.</span></span>

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<td class="old_line diff-line-num" data-linenumber="509" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

509

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<td class="new_line diff-line-num" data-linenumber="595" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

595

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC595" class="line" lang="python"></span>

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<td class="old_line diff-line-num new" data-linenumber="510" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="596" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

596

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC596" class="line" lang="python">    <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">mask_skip_count</span><span class="p">:</span></span>

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<td class="old_line diff-line-num new" data-linenumber="510" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="597" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

597

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC597" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">print</span><span class="p">(</span><span class="sa">f</span><span class="sh" style="color: #dd1144;">"</span><span class="si" style="color: #dd1144;">{</span><span class="n" style="color: #333333;">mask_skip_count</span><span class="si" style="color: #dd1144;">}</span><span class="s" style="color: #dd1144;"> positions were skipped due to the provided mask</span><span class="sh" style="color: #dd1144;">"</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="510" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="598" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

598

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC598" class="line" lang="python"></span>

</pre></td>

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510

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599

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC599" class="line" lang="python">    <span class="k" style="font-weight: 600;">if</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">inferred_const_sites</span><span class="sh" style="color: #dd1144;">'</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">tree_dict</span> <span class="ow" style="font-weight: 600;">and</span> <span class="n" style="color: #333333;">explainedErrors</span> <span class="o" style="font-weight: 600;">!=</span> <span class="mi" style="color: #009999;">0</span><span class="p">:</span></span>

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511

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600

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC600" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">print</span><span class="p">(</span><span class="nf" style="color: #990000; font-weight: 600;">fill</span><span class="p">(</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">Sites that were constant except for ambiguous bases were made</span><span class="sh" style="color: #dd1144;">"</span> <span class="o" style="font-weight: 600;">+</span></span>

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512

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<td class="new_line diff-line-num" data-linenumber="601" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

601

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC601" class="line" lang="python">                   <span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;"> constant by TreeTime. This happened {} times. These sites are</span><span class="sh" style="color: #dd1144;">"</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">format</span><span class="p">(</span><span class="n" style="color: #333333;">explainedErrors</span><span class="p">)</span> <span class="o" style="font-weight: 600;">+</span></span>

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<li id="884b9238819e29c9c3a7ccd69fd2f6ed9f2fab18">

<a href="https://salsa.debian.org/med-team/python-treetime/-/commit/e6064017dcfbf63072b9d8a06cc5775d5eff2f6e#884b9238819e29c9c3a7ccd69fd2f6ed9f2fab18"><strong style="font-weight: 600;">treetime/wrappers.py</strong></a>

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<td class="line_content match" style="color: rgba(5,5,6,.24); padding: inherit;" bgcolor="#fbfafd">@@ -521,7 +521,7 @@ def ancestral_reconstruction(params):</td>

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521

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521

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC521" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">### OUTPUT and saving of results</span></span>

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522

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522

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC522" class="line" lang="python">    <span class="c1" style="color: #999988; font-style: italic;">###########################################################################</span></span>

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523

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<td class="new_line diff-line-num" data-linenumber="523" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

523

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC523" class="line" lang="python">    <span class="k" style="font-weight: 600;">if</span> <span class="n" style="color: #333333;">params</span><span class="p">.</span><span class="n" style="color: #333333;">gtr</span><span class="o" style="font-weight: 600;">==</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">infer</span><span class="sh" style="color: #dd1144;">'</span><span class="p">:</span></span>

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<td class="old_line diff-line-num old" data-linenumber="524" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

524

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<td class="new_line diff-line-num old" data-linenumber="524" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

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<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC524" class="line" lang="python">        <span class="n" style="color: #333333;">fname</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">outdir</span><span class="o" style="font-weight: 600;">+</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;"><span class="idiff left right deletion" style="background-color: #fac5cd;">/</span>sequence_evolution_model.txt</span><span class="sh" style="color: #dd1144;">'</span></span>

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<td class="old_line diff-line-num new" data-linenumber="525" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="524" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

524

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<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC524" class="line" lang="python">        <span class="n" style="color: #333333;">fname</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">outdir</span><span class="o" style="font-weight: 600;">+</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">sequence_evolution_model.txt</span><span class="sh" style="color: #dd1144;">'</span></span>

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525

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<td class="new_line diff-line-num" data-linenumber="525" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

525

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC525" class="line" lang="python">        <span class="k" style="font-weight: 600;">with</span> <span class="nf" style="color: #990000; font-weight: 600;">open</span><span class="p">(</span><span class="n" style="color: #333333;">fname</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">w</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="n" style="color: #333333;">encoding</span><span class="o" style="font-weight: 600;">=</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">utf-8</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span> <span class="k" style="font-weight: 600;">as</span> <span class="n" style="color: #333333;">ofile</span><span class="p">:</span></span>

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526

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<td class="new_line diff-line-num" data-linenumber="526" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

526

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC526" class="line" lang="python">            <span class="n" style="color: #333333;">ofile</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">write</span><span class="p">(</span><span class="nf" style="color: #990000; font-weight: 600;">str</span><span class="p">(</span><span class="n" style="color: #333333;">treeanc</span><span class="p">.</span><span class="n" style="color: #333333;">gtr</span><span class="p">)</span><span class="o" style="font-weight: 600;">+</span><span class="sh" style="color: #dd1144;">'</span><span class="se" style="color: #dd1144;">\n</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

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527

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<td class="new_line diff-line-num" data-linenumber="527" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

527

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC527" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">print</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="se" style="color: #dd1144;">\n</span><span class="s" style="color: #dd1144;">Inferred sequence evolution model (saved as %s):</span><span class="sh" style="color: #dd1144;">'</span><span class="o" style="font-weight: 600;">%</span><span class="n" style="color: #333333;">fname</span><span class="p">)</span></span>

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<td class="line_content match" style="color: rgba(5,5,6,.24); padding: inherit;" bgcolor="#fbfafd">@@ -854,11 +854,25 @@ def estimate_clock_model(params):</td>

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854

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854

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC854" class="line" lang="python">    <span class="k" style="font-weight: 600;">else</span><span class="p">:</span></span>

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<td class="old_line diff-line-num" data-linenumber="855" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

855

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<td class="new_line diff-line-num" data-linenumber="855" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

855

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC855" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">print</span><span class="p">(</span><span class="sh" style="color: #dd1144;">'</span><span class="se" style="color: #dd1144;">\n</span><span class="s" style="color: #dd1144;">--- root-date:</span><span class="se" style="color: #dd1144;">\t</span><span class="s" style="color: #dd1144;"> %3.2f</span><span class="se" style="color: #dd1144;">\n\n</span><span class="sh" style="color: #dd1144;">'</span><span class="o" style="font-weight: 600;">%</span><span class="p">(</span><span class="o" style="font-weight: 600;">-</span><span class="n" style="color: #333333;">d2d</span><span class="p">.</span><span class="n" style="color: #333333;">intercept</span><span class="o" style="font-weight: 600;">/</span><span class="n" style="color: #333333;">d2d</span><span class="p">.</span><span class="n" style="color: #333333;">clock_rate</span><span class="p">))</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="856" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

856

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<td class="new_line diff-line-num" data-linenumber="856" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

856

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<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC856" class="line" lang="python"></span>

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<td class="old_line diff-line-num new" data-linenumber="857" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="857" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

857

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC857" class="line" lang="python">    <span class="k" style="font-weight: 600;">if</span> <span class="nf" style="color: #990000; font-weight: 600;">hasattr</span><span class="p">(</span><span class="n" style="color: #333333;">myTree</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">outliers</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span> <span class="ow" style="font-weight: 600;">and</span> <span class="n" style="color: #333333;">myTree</span><span class="p">.</span><span class="n" style="color: #333333;">outliers</span> <span class="ow" style="font-weight: 600;">is</span> <span class="ow" style="font-weight: 600;">not</span> <span class="bp" style="color: #999999;">None</span><span class="p">:</span></span>

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<td class="old_line diff-line-num new" data-linenumber="857" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="858" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

858

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC858" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">print</span><span class="p">(</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">--- saved detected outliers as </span><span class="sh" style="color: #dd1144;">"</span> <span class="o" style="font-weight: 600;">+</span> <span class="n" style="color: #333333;">basename</span> <span class="o" style="font-weight: 600;">+</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">outliers.tsv</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="857" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="859" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

859

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC859" class="line" lang="python">        <span class="n" style="color: #333333;">myTree</span><span class="p">.</span><span class="n" style="color: #333333;">outliers</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">to_csv</span><span class="p">(</span><span class="n" style="color: #333333;">basename</span> <span class="o" style="font-weight: 600;">+</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">outliers.tsv</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="n" style="color: #333333;">sep</span><span class="o" style="font-weight: 600;">=</span><span class="sh" style="color: #dd1144;">'</span><span class="se" style="color: #dd1144;">\t</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="857" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="860" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

860

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC860" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="857" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="861" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

861

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC861" class="line" lang="python">    <span class="k" style="font-weight: 600;">if</span> <span class="nf" style="color: #990000; font-weight: 600;">hasattr</span><span class="p">(</span><span class="n" style="color: #333333;">myTree</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">outliers</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span> <span class="ow" style="font-weight: 600;">and</span> <span class="n" style="color: #333333;">myTree</span><span class="p">.</span><span class="n" style="color: #333333;">outliers</span> <span class="ow" style="font-weight: 600;">is</span> <span class="ow" style="font-weight: 600;">not</span> <span class="bp" style="color: #999999;">None</span> <span class="ow" style="font-weight: 600;">and</span> <span class="n" style="color: #333333;">params</span><span class="p">.</span><span class="n" style="color: #333333;">prune_outliers</span><span class="p">:</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="862" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

862

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC862" class="line" lang="python">        <span class="k" style="font-weight: 600;">for</span> <span class="n" style="color: #333333;">outlier</span> <span class="ow" style="font-weight: 600;">in</span> <span class="n" style="color: #333333;">myTree</span><span class="p">.</span><span class="n" style="color: #333333;">outliers</span><span class="p">.</span><span class="n" style="color: #333333;">index</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="857" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

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<td class="new_line diff-line-num new" data-linenumber="863" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

863

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC863" class="line" lang="python">            <span class="nf" style="color: #990000; font-weight: 600;">print</span><span class="p">(</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">removing </span><span class="sh" style="color: #dd1144;">"</span><span class="p">,</span> <span class="n" style="color: #333333;">outlier</span><span class="p">)</span></span>

</pre></td>

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<td class="new_line diff-line-num new" data-linenumber="864" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

864

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC864" class="line" lang="python">            <span class="n" style="color: #333333;">myTree</span><span class="p">.</span><span class="n" style="color: #333333;">tree</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">prune</span><span class="p">(</span><span class="n" style="color: #333333;">outlier</span><span class="p">)</span></span>

</pre></td>

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865

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC865" class="line" lang="python"></span>

</pre></td>

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857

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866

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC866" class="line" lang="python">    <span class="k" style="font-weight: 600;">if</span> <span class="ow" style="font-weight: 600;">not</span> <span class="n" style="color: #333333;">params</span><span class="p">.</span><span class="n" style="color: #333333;">keep_root</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="858" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

858

</td>

<td class="new_line diff-line-num" data-linenumber="867" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

867

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC867" class="line" lang="python">        <span class="c1" style="color: #999988; font-style: italic;"># write rerooted tree to file</span></span>

</pre></td>

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<td class="old_line diff-line-num" data-linenumber="859" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

859

</td>

<td class="new_line diff-line-num" data-linenumber="868" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

868

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC868" class="line" lang="python">        <span class="n" style="color: #333333;">outtree_name</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">basename</span><span class="o" style="font-weight: 600;">+</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">rerooted.newick</span><span class="sh" style="color: #dd1144;">'</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="860" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

860

</td>

<td class="new_line diff-line-num old" data-linenumber="869" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC860" class="line" lang="python">        <span class="n" style="color: #333333;">Phylo</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">write</span><span class="p">(</span><span class="n" style="color: #333333;">myTree</span><span class="p">.</span><span class="n" style="color: #333333;">tree</span><span class="p">,</span> <span class="n" style="color: #333333;">outtree_name</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">newick</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num old" data-linenumber="861" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

861

</td>

<td class="new_line diff-line-num old" data-linenumber="869" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #fac5cd; border-right-style: solid; padding: inherit;" align="right" bgcolor="#f9d7dc">

</td>

<td class="line_content old" style="padding: inherit;" bgcolor="#fbe9eb"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>-<span id="LC861" class="line" lang="python">        <span class="nf" style="color: #990000; font-weight: 600;">print</span><span class="p">(</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">--- re-rooted tree written to </span><span class="se" style="color: #dd1144;">\n\t</span><span class="s" style="color: #dd1144;">%s</span><span class="se" style="color: #dd1144;">\n</span><span class="sh" style="color: #dd1144;">"</span><span class="o" style="font-weight: 600;">%</span><span class="n" style="color: #333333;">outtree_name</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="862" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="869" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

869

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC869" class="line" lang="python">    <span class="k" style="font-weight: 600;">elif</span> <span class="n" style="color: #333333;">params</span><span class="p">.</span><span class="n" style="color: #333333;">prune_outliers</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="862" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="870" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

870

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC870" class="line" lang="python">        <span class="n" style="color: #333333;">outtree_name</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">basename</span><span class="o" style="font-weight: 600;">+</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">pruned.newick</span><span class="sh" style="color: #dd1144;">'</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="862" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="871" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

871

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC871" class="line" lang="python">    <span class="k" style="font-weight: 600;">else</span><span class="p">:</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="862" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="872" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

872

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC872" class="line" lang="python">        <span class="n" style="color: #333333;">outtree_name</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">basename</span><span class="o" style="font-weight: 600;">+</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">.output.newick</span><span class="sh" style="color: #dd1144;">'</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="862" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="873" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

873

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC873" class="line" lang="python"></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="862" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="874" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

874

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC874" class="line" lang="python">    <span class="n" style="color: #333333;">Phylo</span><span class="p">.</span><span class="nf" style="color: #990000; font-weight: 600;">write</span><span class="p">(</span><span class="n" style="color: #333333;">myTree</span><span class="p">.</span><span class="n" style="color: #333333;">tree</span><span class="p">,</span> <span class="n" style="color: #333333;">outtree_name</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">newick</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span></span>

</pre></td>

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<td class="old_line diff-line-num new" data-linenumber="862" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

</td>

<td class="new_line diff-line-num new" data-linenumber="875" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #c7f0d2; border-right-style: solid; padding: inherit;" align="right" bgcolor="#ddfbe6">

875

</td>

<td class="line_content new" style="padding: inherit;" bgcolor="#ecfdf0"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'>+<span id="LC875" class="line" lang="python">    <span class="nf" style="color: #990000; font-weight: 600;">print</span><span class="p">(</span><span class="sh" style="color: #dd1144;">"</span><span class="s" style="color: #dd1144;">--- new tree written to </span><span class="se" style="color: #dd1144;">\n\t</span><span class="s" style="color: #dd1144;">%s</span><span class="se" style="color: #dd1144;">\n</span><span class="sh" style="color: #dd1144;">"</span><span class="o" style="font-weight: 600;">%</span><span class="n" style="color: #333333;">outtree_name</span><span class="p">)</span></span>

</pre></td>

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862

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<td class="new_line diff-line-num" data-linenumber="876" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

876

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC876" class="line" lang="python"></span>

</pre></td>

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863

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<td class="new_line diff-line-num" data-linenumber="877" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

877

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC877" class="line" lang="python">    <span class="n" style="color: #333333;">table_fname</span> <span class="o" style="font-weight: 600;">=</span> <span class="n" style="color: #333333;">basename</span><span class="o" style="font-weight: 600;">+</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">rtt.csv</span><span class="sh" style="color: #dd1144;">'</span></span>

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<tr class="line_holder" style="line-height: 1.6;">

<td class="old_line diff-line-num" data-linenumber="864" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

864

</td>

<td class="new_line diff-line-num" data-linenumber="878" style="width: 35px; color: rgba(5,5,6,.24); border-right-width: 1px; border-right-color: #ececef; border-right-style: solid; padding: inherit;" align="right" bgcolor="#fbfafd">

878

</td>

<td class="line_content" style="padding: inherit;"><pre style='display: block; font-size: 14px; color: #28272d; position: relative; font-family: "GitLab Mono","JetBrains Mono","Menlo","DejaVu Sans Mono","Liberation Mono","Consolas","Ubuntu Mono","Courier New","andale mono","lucida console",monospace; word-break: break-all; word-wrap: break-word; background-color: inherit; border-radius: 2px; margin: 0; padding: 0; border: inherit solid #dcdcde;'> <span id="LC878" class="line" lang="python">    <span class="k" style="font-weight: 600;">with</span> <span class="nf" style="color: #990000; font-weight: 600;">open</span><span class="p">(</span><span class="n" style="color: #333333;">table_fname</span><span class="p">,</span> <span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">w</span><span class="sh" style="color: #dd1144;">'</span><span class="p">,</span> <span class="n" style="color: #333333;">encoding</span><span class="o" style="font-weight: 600;">=</span><span class="sh" style="color: #dd1144;">'</span><span class="s" style="color: #dd1144;">utf-8</span><span class="sh" style="color: #dd1144;">'</span><span class="p">)</span> <span class="k" style="font-weight: 600;">as</span> <span class="n" style="color: #333333;">ofile</span><span class="p">:</span></span>

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