[Blends-commit] r2897 - /projects/med/trunk/debian-med/tasks/bio

[tille at users.alioth.debian.org]

Author: tille
Date: Mon Jul 18 07:20:12 2011
New Revision: 2897

URL: http://svn.debian.org/wsvn/blends/?sc=1&rev=2897
Log:
Added disulfinder

Modified:
    projects/med/trunk/debian-med/tasks/bio

Modified: projects/med/trunk/debian-med/tasks/bio
URL: http://svn.debian.org/wsvn/blends/projects/med/trunk/debian-med/tasks/bio?rev=2897&op=diff
==============================================================================
--- projects/med/trunk/debian-med/tasks/bio (original)
+++ projects/med/trunk/debian-med/tasks/bio Mon Jul 18 07:20:12 2011
@@ -3824,6 +3824,26 @@
  .
  The reaper module is used underneath the http://genenetwork.org site.
 
+Depends: disulfinder
+WNPP: 634177
+Homepage: http://disulfind.dsi.unifi.it/
+License: GPL2+
+Pkg-Description: prediction of S-S bonds in proteins
+ 'disulfinder' is for predicting the disulfide bonding state of cysteines
+ and their disulfide connectivity starting from sequence alone. Disulfide
+ bridges play a major role in the stabilization of the folding process for
+ several proteins. Prediction of disulfide bridges from sequence alone is
+ therefore useful for the study of structural and functional properties
+ of specific proteins. In addition, knowledge about the disulfide bonding
+ state of cysteines may help the experimental structure determination
+ process and may be useful in other genomic annotation tasks.
+ .
+ 'disulfinder' predicts disulfide patterns in two computational stages:
+ (1) the disulfide bonding state of each cysteine is predicted by a
+ BRNN-SVM binary classifier; (2) cysteines that are known to participate
+ in the formation of bridges are paired by a Recursive Neural Network
+ to obtain a connectivity pattern.
+
 
 Comment: Several related R packages are listed at CRAN:
          http://cran.r-project.org/web/views/Genetics.html