[med-svn] r291 - in trunk/packages: . rnahybrid rnahybrid/branches rnahybrid/branches/upstream rnahybrid/branches/upstream/current rnahybrid/branches/upstream/current/examples rnahybrid/branches/upstream/current/man rnahybrid/branches/upstream/current/src
charles-guest at alioth.debian.org
charles-guest at alioth.debian.org
Fri Jun 1 00:53:52 UTC 2007
Author: charles-guest
Date: 2007-06-01 00:53:51 +0000 (Fri, 01 Jun 2007)
New Revision: 291
Added:
trunk/packages/rnahybrid/
trunk/packages/rnahybrid/branches/
trunk/packages/rnahybrid/branches/upstream/
trunk/packages/rnahybrid/branches/upstream/current/
trunk/packages/rnahybrid/branches/upstream/current/AUTHORS
trunk/packages/rnahybrid/branches/upstream/current/COPYING
trunk/packages/rnahybrid/branches/upstream/current/ChangeLog
trunk/packages/rnahybrid/branches/upstream/current/INSTALL
trunk/packages/rnahybrid/branches/upstream/current/Makefile.am
trunk/packages/rnahybrid/branches/upstream/current/Makefile.in
trunk/packages/rnahybrid/branches/upstream/current/NEWS
trunk/packages/rnahybrid/branches/upstream/current/README
trunk/packages/rnahybrid/branches/upstream/current/aclocal.m4
trunk/packages/rnahybrid/branches/upstream/current/config.guess
trunk/packages/rnahybrid/branches/upstream/current/config.h.in
trunk/packages/rnahybrid/branches/upstream/current/configure
trunk/packages/rnahybrid/branches/upstream/current/configure.in
trunk/packages/rnahybrid/branches/upstream/current/depcomp
trunk/packages/rnahybrid/branches/upstream/current/examples/
trunk/packages/rnahybrid/branches/upstream/current/examples/3UTR_fly.freq
trunk/packages/rnahybrid/branches/upstream/current/examples/3UTR_human.freq
trunk/packages/rnahybrid/branches/upstream/current/examples/3UTR_worm.freq
trunk/packages/rnahybrid/branches/upstream/current/examples/cbr-hbl-1.fasta
trunk/packages/rnahybrid/branches/upstream/current/examples/cel-hbl-1.fasta
trunk/packages/rnahybrid/branches/upstream/current/examples/cel-let-7.fasta
trunk/packages/rnahybrid/branches/upstream/current/examples/coding_fly.freq
trunk/packages/rnahybrid/branches/upstream/current/examples/coding_worm.freq
trunk/packages/rnahybrid/branches/upstream/current/examples/hbl-1.fasta
trunk/packages/rnahybrid/branches/upstream/current/install-sh
trunk/packages/rnahybrid/branches/upstream/current/man/
trunk/packages/rnahybrid/branches/upstream/current/man/Makefile.am
trunk/packages/rnahybrid/branches/upstream/current/man/Makefile.in
trunk/packages/rnahybrid/branches/upstream/current/man/RNAcalibrate.1
trunk/packages/rnahybrid/branches/upstream/current/man/RNAeffective.1
trunk/packages/rnahybrid/branches/upstream/current/man/RNAhybrid.1
trunk/packages/rnahybrid/branches/upstream/current/missing
trunk/packages/rnahybrid/branches/upstream/current/mkinstalldirs
trunk/packages/rnahybrid/branches/upstream/current/src/
trunk/packages/rnahybrid/branches/upstream/current/src/Makefile.am
trunk/packages/rnahybrid/branches/upstream/current/src/Makefile.in
trunk/packages/rnahybrid/branches/upstream/current/src/energy.c
trunk/packages/rnahybrid/branches/upstream/current/src/energy.h
trunk/packages/rnahybrid/branches/upstream/current/src/fasta.c
trunk/packages/rnahybrid/branches/upstream/current/src/fasta.h
trunk/packages/rnahybrid/branches/upstream/current/src/globals.h
trunk/packages/rnahybrid/branches/upstream/current/src/hybrid_core.c
trunk/packages/rnahybrid/branches/upstream/current/src/hybrid_core.h
trunk/packages/rnahybrid/branches/upstream/current/src/input.c
trunk/packages/rnahybrid/branches/upstream/current/src/input.h
trunk/packages/rnahybrid/branches/upstream/current/src/minmax.h
trunk/packages/rnahybrid/branches/upstream/current/src/mt19937-1.c
trunk/packages/rnahybrid/branches/upstream/current/src/mt19937-1.h
trunk/packages/rnahybrid/branches/upstream/current/src/numerical.c
trunk/packages/rnahybrid/branches/upstream/current/src/numerical.h
trunk/packages/rnahybrid/branches/upstream/current/src/plot.c
trunk/packages/rnahybrid/branches/upstream/current/src/plot.h
trunk/packages/rnahybrid/branches/upstream/current/src/random.c
trunk/packages/rnahybrid/branches/upstream/current/src/random.h
trunk/packages/rnahybrid/branches/upstream/current/src/rnacalibrate.c
trunk/packages/rnahybrid/branches/upstream/current/src/rnaeffective.c
trunk/packages/rnahybrid/branches/upstream/current/src/rnahybrid.c
trunk/packages/rnahybrid/tags/
Log:
[svn-inject] Installing original source of rnahybrid
Added: trunk/packages/rnahybrid/branches/upstream/current/AUTHORS
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/AUTHORS (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/AUTHORS 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,3 @@
+Marc Rehmsmeier (marc at techfak.uni-bielefeld.de)
+Peter Steffen (psteffen at techfak.uni-bielefeld.de)
+Matthias Hoechsmann (mhoechsm at techfak.uni-bielefeld.de)
Added: trunk/packages/rnahybrid/branches/upstream/current/COPYING
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/COPYING (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/COPYING 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,340 @@
+ GNU GENERAL PUBLIC LICENSE
+ Version 2, June 1991
+
+ Copyright (C) 1989, 1991 Free Software Foundation, Inc.
+ 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA
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+ Copyright (C) <year> <name of author>
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+ This program is free software; you can redistribute it and/or modify
+ it under the terms of the GNU General Public License as published by
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+ but WITHOUT ANY WARRANTY; without even the implied warranty of
+ MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
+ GNU General Public License for more details.
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+ Gnomovision version 69, Copyright (C) year name of author
+ Gnomovision comes with ABSOLUTELY NO WARRANTY; for details type `show w'.
+ This is free software, and you are welcome to redistribute it
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+
+The hypothetical commands `show w' and `show c' should show the appropriate
+parts of the General Public License. Of course, the commands you use may
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+
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+
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+ `Gnomovision' (which makes passes at compilers) written by James Hacker.
+
+ <signature of Ty Coon>, 1 April 1989
+ Ty Coon, President of Vice
+
+This General Public License does not permit incorporating your program into
+proprietary programs. If your program is a subroutine library, you may
+consider it more useful to permit linking proprietary applications with the
+library. If this is what you want to do, use the GNU Library General
+Public License instead of this License.
Added: trunk/packages/rnahybrid/branches/upstream/current/ChangeLog
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/ChangeLog (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/ChangeLog 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,23 @@
+Tue Nov 16 16:46:51 2004 Marc Rehmsmeier <marc at TechFak.Uni-Bielefeld.DE>
+
+ * RNAcalibrate man page: added description of output (number of
+ data points, location, scale)
+
+ * estimate_evd_parameters now returns the number of data
+ points evd parameters have been estimated on
+
+Mon Nov 15 20:32:43 2004 Marc Rehmsmeier <marc at TechFak.Uni-Bielefeld.DE>
+
+ * Added GNU General Public License to *.c and *.h files.
+
+ * examples directory: renamed and added sequence files.
+
+ * README: augmented (and correct) examples.
+
+ * RNAeffective: proper behaviour for qflag now. Hadn't been
+ working before.
+
+ * Added options -u (maximum internal loop size per sequence) and
+ -v (maximum bulge loop size). (some time ago)
+
+
Added: trunk/packages/rnahybrid/branches/upstream/current/INSTALL
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/INSTALL (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/INSTALL 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,16 @@
+Type
+
+ ./configure
+ make
+ make install
+
+to configure, make and install RNAhybrid. To enable graphical
+output for RNAhybrid, you need the libraries g2 for ps format
+and g2 and gd for png and jpg format. Without these libraries
+only textual output is supported.
+
+
+Type
+ make clean
+
+to remove object files.
Added: trunk/packages/rnahybrid/branches/upstream/current/Makefile.am
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/Makefile.am (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/Makefile.am 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,4 @@
+SUBDIRS = src man
+EXTRA_DIST = examples
+VERSION = 2.1
+
Added: trunk/packages/rnahybrid/branches/upstream/current/Makefile.in
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/Makefile.in (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/Makefile.in 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,501 @@
+# Makefile.in generated by automake 1.7.3 from Makefile.am.
+# @configure_input@
+
+# Copyright 1994, 1995, 1996, 1997, 1998, 1999, 2000, 2001, 2002, 2003
+# Free Software Foundation, Inc.
+# This Makefile.in is free software; the Free Software Foundation
+# gives unlimited permission to copy and/or distribute it,
+# with or without modifications, as long as this notice is preserved.
+
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY, to the extent permitted by law; without
+# even the implied warranty of MERCHANTABILITY or FITNESS FOR A
+# PARTICULAR PURPOSE.
+
+ at SET_MAKE@
+
+srcdir = @srcdir@
+top_srcdir = @top_srcdir@
+VPATH = @srcdir@
+pkgdatadir = $(datadir)/@PACKAGE@
+pkglibdir = $(libdir)/@PACKAGE@
+pkgincludedir = $(includedir)/@PACKAGE@
+top_builddir = .
+
+am__cd = CDPATH="$${ZSH_VERSION+.}$(PATH_SEPARATOR)" && cd
+INSTALL = @INSTALL@
+install_sh_DATA = $(install_sh) -c -m 644
+install_sh_PROGRAM = $(install_sh) -c
+install_sh_SCRIPT = $(install_sh) -c
+INSTALL_HEADER = $(INSTALL_DATA)
+transform = $(program_transform_name)
+NORMAL_INSTALL = :
+PRE_INSTALL = :
+POST_INSTALL = :
+NORMAL_UNINSTALL = :
+PRE_UNINSTALL = :
+POST_UNINSTALL = :
+ACLOCAL = @ACLOCAL@
+AMDEP_FALSE = @AMDEP_FALSE@
+AMDEP_TRUE = @AMDEP_TRUE@
+AMTAR = @AMTAR@
+AUTOCONF = @AUTOCONF@
+AUTOHEADER = @AUTOHEADER@
+AUTOMAKE = @AUTOMAKE@
+AWK = @AWK@
+CC = @CC@
+CCDEPMODE = @CCDEPMODE@
+CFLAGS = @CFLAGS@
+CPP = @CPP@
+CPPFLAGS = @CPPFLAGS@
+CYGPATH_W = @CYGPATH_W@
+DEFS = @DEFS@
+DEPDIR = @DEPDIR@
+ECHO_C = @ECHO_C@
+ECHO_N = @ECHO_N@
+ECHO_T = @ECHO_T@
+EGREP = @EGREP@
+EXEEXT = @EXEEXT@
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Added: trunk/packages/rnahybrid/branches/upstream/current/NEWS
===================================================================
Added: trunk/packages/rnahybrid/branches/upstream/current/README
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/README (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/README 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,130 @@
+RNAhybrid 2.0
+
+RNAhybrid is a tool for finding the minimum free energy hybridisation
+of a long (target) and a short (query) RNA. The hybridisation is
+performed in a kind of domain mode, ie. the short sequence is
+hybridised to the best fitting part of the long one. The tool is
+primarily meant as a means for microRNA target prediction. In
+addition to mfes, the program calculates p-values based on extreme
+value distributions of length normalised energies.
+
+RNAcalibrate is a tool for calibrating minimum free energy (mfe)
+hybridisations performed with RNAhybrid. It searches a random database
+that can be given on the command line or otherwise generates random
+sequences according to given sample size, length distribution
+parameters and dinucleotide frequencies. To the empirical distribution
+of length normalised minimum free energies, parameters of an extreme
+value distribution (evd) are fitted. The resulting location and scale
+parameters of the evd can then be given to RNAhybrid for the
+calculation of mfe p-values.
+
+RNAeffective is a tool for determining the effective number of
+orthologous miRNA targets. This number can be used for the
+calculation of more accurate joint p-values in multi-species
+analyses. RNAeffective searches a set of target sequences with random
+miRNAs that can be given on the command line or otherwise generates
+random sequences according to given sample size, length distribution
+parameters and dinucleotide frequencies. The empirical distribution of
+joint p-values is compared to the p-values themselves, and the
+effective number of independent targets is the one that reduces the
+deviation between the two distributions.
+
+
+For installation, see the file INSTALL.
+
+
+After installation, try the following examples (make sure that RNAhybrid,
+RNAcalibrate and RNAeffective are in your PATH by then):
+
+
+ RNAhybrid -s 3utr_worm -t examples/cel-hbl-1.fasta -q examples/cel-let-7.fasta
+
+
+This searches the C. elegans hbl-1 3'UTR with the C. elegans let-7
+miRNA. The option -s tells RNAhybrid to quickly estimate statistical
+parameters from "minimal duplex energies" under the assumption that
+the target sequences are worm (C. elegans, to be precise) 3'UTR
+sequences. You can also use 3utr_fly and 3utr_human.
+
+To get a better estimate of statistical parameters, use RNAcalibrate:
+
+
+ RNAcalibrate -d examples/3UTR_worm.freq -k 50 -l 50,30 -q examples/cel-let-7.fasta
+
+
+This generates 50 random sequences with lengths distributed according
+to a normal (Gaussian) distribution with mean 50 and standard
+deviation 30, following the dinucleotide distribution that is defined
+in the file 3UTR_worm.freq in the examples dicrectory. The output are
+the parameters of an extreme value distribution (location and
+shape). Since with 50 random sequences the estimate is not very
+accurate, you should use larger numbers of several thousand. Default
+values for -k and -l are 5000 and 500,300, respectively, so you can
+omit these options.
+
+The estimated parameters can be used with RNAhybrid for accurate
+p-value calculation of length normalised minimum free energies:
+
+
+RNAhybrid -d 1.9,0.28 -t examples/cel-hbl-1.fasta -q examples/cel-let-7.fasta
+
+
+Here, 1.9 is the location parameter and 0.28 the shape parameter of
+the assumed extreme value distribution.
+
+If you want to force miRNA/target duplexes to have a helix in a specified
+part, for example at the 5'-end of the miRNA, use the -f option:
+
+
+RNAhybrid -f 2,7 -d 1.9,0.28 -t examples/cel-hbl-1.fasta -q examples/cel-let-7.fasta
+
+
+-f 2,7 tells RNAhybrid to force the duplexes to have a helix (ie. an
+uninterrupted stretch of base pairs, no bulges, no internal loops)
+from nucleotide 2 to nucleotide 7 in the miRNA.
+
+Since such a structural constraint affects the statistical
+significance of matches, you should use RNAcalibrate with the same
+constraint:
+
+
+RNAcalibrate -f 2,7 -d examples/3UTR_worm.freq -k 50 -l 50,30 -q examples/cel-let-7.fasta
+
+
+Be aware that you might need a larger sample (larger -k value) to get
+a good estimate of statistical parameters, especially for shorter
+sequences. This is, because it is not for all miRNA/target
+combinations possible to form a helix at the specified positions.
+
+To get a feeling of how stable the parameter estimates are, repeat the
+calibration several times and have a look at the resulting values.
+
+
+In a cross-species analysis, you would search C. briggsae sequences as
+well:
+
+
+RNAhybrid -s 3utr_worm -t examples/cbr-hbl-1.fasta -q examples/cel-let-7.fasta
+
+
+To assess how much evidence the use of multiple species adds, you can
+calculate the effective number of orthologous sequences:
+
+
+RNAeffective -k 30 -s -t examples/hbl-1.fasta -q examples/cel-let-7.fasta
+
+
+Here, hbl-1.fasta contains both hbl-1 3'UTR sequences (C. elegans and
+C. briggsae). The output tells you an effective number of 1.3, which
+means that the two sequences are statistically rather dependent, and
+that it is not that surprising to find a good hit in cbr-hbl-1 if you
+have found one in cel-hbl-1. The closer the effective number is to the
+actual number (2 in this example), the statistically more independent
+the sequences are. Like in the RNAcalibrate examples, the -k option
+should take larger values, although the calculations are very time
+consuming.
+
+
+In general, target files (-t option) and query (miRNA) files (-q
+option) can be multiple fasta files. The searches are performed in all
+combinations (all queries vs. all targets).
Added: trunk/packages/rnahybrid/branches/upstream/current/aclocal.m4
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/aclocal.m4 (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/aclocal.m4 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,852 @@
+# generated automatically by aclocal 1.7.3 -*- Autoconf -*-
+
+# Copyright (C) 1996, 1997, 1998, 1999, 2000, 2001, 2002
+# Free Software Foundation, Inc.
+# This file is free software; the Free Software Foundation
+# gives unlimited permission to copy and/or distribute it,
+# with or without modifications, as long as this notice is preserved.
+
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY, to the extent permitted by law; without
+# even the implied warranty of MERCHANTABILITY or FITNESS FOR A
+# PARTICULAR PURPOSE.
+
+# Do all the work for Automake. -*- Autoconf -*-
+
+# This macro actually does too much some checks are only needed if
+# your package does certain things. But this isn't really a big deal.
+
+# Copyright 1996, 1997, 1998, 1999, 2000, 2001, 2002, 2003
+# Free Software Foundation, Inc.
+
+# This program is free software; you can redistribute it and/or modify
+# it under the terms of the GNU General Public License as published by
+# the Free Software Foundation; either version 2, or (at your option)
+# any later version.
+
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
+# GNU General Public License for more details.
+
+# You should have received a copy of the GNU General Public License
+# along with this program; if not, write to the Free Software
+# Foundation, Inc., 59 Temple Place - Suite 330, Boston, MA
+# 02111-1307, USA.
+
+# serial 9
+
+# There are a few dirty hacks below to avoid letting `AC_PROG_CC' be
+# written in clear, in which case automake, when reading aclocal.m4,
+# will think it sees a *use*, and therefore will trigger all it's
+# C support machinery. Also note that it means that autoscan, seeing
+# CC etc. in the Makefile, will ask for an AC_PROG_CC use...
+
+
+AC_PREREQ([2.54])
+
+# Autoconf 2.50 wants to disallow AM_ names. We explicitly allow
+# the ones we care about.
+m4_pattern_allow([^AM_[A-Z]+FLAGS$])dnl
+
+# AM_INIT_AUTOMAKE(PACKAGE, VERSION, [NO-DEFINE])
+# AM_INIT_AUTOMAKE([OPTIONS])
+# -----------------------------------------------
+# The call with PACKAGE and VERSION arguments is the old style
+# call (pre autoconf-2.50), which is being phased out. PACKAGE
+# and VERSION should now be passed to AC_INIT and removed from
+# the call to AM_INIT_AUTOMAKE.
+# We support both call styles for the transition. After
+# the next Automake release, Autoconf can make the AC_INIT
+# arguments mandatory, and then we can depend on a new Autoconf
+# release and drop the old call support.
+AC_DEFUN([AM_INIT_AUTOMAKE],
+[AC_REQUIRE([AM_SET_CURRENT_AUTOMAKE_VERSION])dnl
+ AC_REQUIRE([AC_PROG_INSTALL])dnl
+# test to see if srcdir already configured
+if test "`cd $srcdir && pwd`" != "`pwd`" &&
+ test -f $srcdir/config.status; then
+ AC_MSG_ERROR([source directory already configured; run "make distclean" there first])
+fi
+
+# test whether we have cygpath
+if test -z "$CYGPATH_W"; then
+ if (cygpath --version) >/dev/null 2>/dev/null; then
+ CYGPATH_W='cygpath -w'
+ else
+ CYGPATH_W=echo
+ fi
+fi
+AC_SUBST([CYGPATH_W])
+
+# Define the identity of the package.
+dnl Distinguish between old-style and new-style calls.
+m4_ifval([$2],
+[m4_ifval([$3], [_AM_SET_OPTION([no-define])])dnl
+ AC_SUBST([PACKAGE], [$1])dnl
+ AC_SUBST([VERSION], [$2])],
+[_AM_SET_OPTIONS([$1])dnl
+ AC_SUBST([PACKAGE], ['AC_PACKAGE_TARNAME'])dnl
+ AC_SUBST([VERSION], ['AC_PACKAGE_VERSION'])])dnl
+
+_AM_IF_OPTION([no-define],,
+[AC_DEFINE_UNQUOTED(PACKAGE, "$PACKAGE", [Name of package])
+ AC_DEFINE_UNQUOTED(VERSION, "$VERSION", [Version number of package])])dnl
+
+# Some tools Automake needs.
+AC_REQUIRE([AM_SANITY_CHECK])dnl
+AC_REQUIRE([AC_ARG_PROGRAM])dnl
+AM_MISSING_PROG(ACLOCAL, aclocal-${am__api_version})
+AM_MISSING_PROG(AUTOCONF, autoconf)
+AM_MISSING_PROG(AUTOMAKE, automake-${am__api_version})
+AM_MISSING_PROG(AUTOHEADER, autoheader)
+AM_MISSING_PROG(MAKEINFO, makeinfo)
+AM_MISSING_PROG(AMTAR, tar)
+AM_PROG_INSTALL_SH
+AM_PROG_INSTALL_STRIP
+# We need awk for the "check" target. The system "awk" is bad on
+# some platforms.
+AC_REQUIRE([AC_PROG_AWK])dnl
+AC_REQUIRE([AC_PROG_MAKE_SET])dnl
+AC_REQUIRE([AM_SET_LEADING_DOT])dnl
+
+_AM_IF_OPTION([no-dependencies],,
+[AC_PROVIDE_IFELSE([AC_PROG_CC],
+ [_AM_DEPENDENCIES(CC)],
+ [define([AC_PROG_CC],
+ defn([AC_PROG_CC])[_AM_DEPENDENCIES(CC)])])dnl
+AC_PROVIDE_IFELSE([AC_PROG_CXX],
+ [_AM_DEPENDENCIES(CXX)],
+ [define([AC_PROG_CXX],
+ defn([AC_PROG_CXX])[_AM_DEPENDENCIES(CXX)])])dnl
+])
+])
+
+
+# When config.status generates a header, we must update the stamp-h file.
+# This file resides in the same directory as the config header
+# that is generated. The stamp files are numbered to have different names.
+
+# Autoconf calls _AC_AM_CONFIG_HEADER_HOOK (when defined) in the
+# loop where config.status creates the headers, so we can generate
+# our stamp files there.
+AC_DEFUN([_AC_AM_CONFIG_HEADER_HOOK],
+[# Compute $1's index in $config_headers.
+_am_stamp_count=1
+for _am_header in $config_headers :; do
+ case $_am_header in
+ $1 | $1:* )
+ break ;;
+ * )
+ _am_stamp_count=`expr $_am_stamp_count + 1` ;;
+ esac
+done
+echo "timestamp for $1" >`AS_DIRNAME([$1])`/stamp-h[]$_am_stamp_count])
+
+# Copyright 2002 Free Software Foundation, Inc.
+
+# This program is free software; you can redistribute it and/or modify
+# it under the terms of the GNU General Public License as published by
+# the Free Software Foundation; either version 2, or (at your option)
+# any later version.
+
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
+# GNU General Public License for more details.
+
+# You should have received a copy of the GNU General Public License
+# along with this program; if not, write to the Free Software
+# Foundation, Inc., 59 Temple Place - Suite 330, Boston, MA
+
+# AM_AUTOMAKE_VERSION(VERSION)
+# ----------------------------
+# Automake X.Y traces this macro to ensure aclocal.m4 has been
+# generated from the m4 files accompanying Automake X.Y.
+AC_DEFUN([AM_AUTOMAKE_VERSION],[am__api_version="1.7"])
+
+# AM_SET_CURRENT_AUTOMAKE_VERSION
+# -------------------------------
+# Call AM_AUTOMAKE_VERSION so it can be traced.
+# This function is AC_REQUIREd by AC_INIT_AUTOMAKE.
+AC_DEFUN([AM_SET_CURRENT_AUTOMAKE_VERSION],
+ [AM_AUTOMAKE_VERSION([1.7.3])])
+
+# Helper functions for option handling. -*- Autoconf -*-
+
+# Copyright 2001, 2002 Free Software Foundation, Inc.
+
+# This program is free software; you can redistribute it and/or modify
+# it under the terms of the GNU General Public License as published by
+# the Free Software Foundation; either version 2, or (at your option)
+# any later version.
+
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
+# GNU General Public License for more details.
+
+# You should have received a copy of the GNU General Public License
+# along with this program; if not, write to the Free Software
+# Foundation, Inc., 59 Temple Place - Suite 330, Boston, MA
+# 02111-1307, USA.
+
+# serial 2
+
+# _AM_MANGLE_OPTION(NAME)
+# -----------------------
+AC_DEFUN([_AM_MANGLE_OPTION],
+[[_AM_OPTION_]m4_bpatsubst($1, [[^a-zA-Z0-9_]], [_])])
+
+# _AM_SET_OPTION(NAME)
+# ------------------------------
+# Set option NAME. Presently that only means defining a flag for this option.
+AC_DEFUN([_AM_SET_OPTION],
+[m4_define(_AM_MANGLE_OPTION([$1]), 1)])
+
+# _AM_SET_OPTIONS(OPTIONS)
+# ----------------------------------
+# OPTIONS is a space-separated list of Automake options.
+AC_DEFUN([_AM_SET_OPTIONS],
+[AC_FOREACH([_AM_Option], [$1], [_AM_SET_OPTION(_AM_Option)])])
+
+# _AM_IF_OPTION(OPTION, IF-SET, [IF-NOT-SET])
+# -------------------------------------------
+# Execute IF-SET if OPTION is set, IF-NOT-SET otherwise.
+AC_DEFUN([_AM_IF_OPTION],
+[m4_ifset(_AM_MANGLE_OPTION([$1]), [$2], [$3])])
+
+#
+# Check to make sure that the build environment is sane.
+#
+
+# Copyright 1996, 1997, 2000, 2001 Free Software Foundation, Inc.
+
+# This program is free software; you can redistribute it and/or modify
+# it under the terms of the GNU General Public License as published by
+# the Free Software Foundation; either version 2, or (at your option)
+# any later version.
+
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
+# GNU General Public License for more details.
+
+# You should have received a copy of the GNU General Public License
+# along with this program; if not, write to the Free Software
+# Foundation, Inc., 59 Temple Place - Suite 330, Boston, MA
+# 02111-1307, USA.
+
+# serial 3
+
+# AM_SANITY_CHECK
+# ---------------
+AC_DEFUN([AM_SANITY_CHECK],
+[AC_MSG_CHECKING([whether build environment is sane])
+# Just in case
+sleep 1
+echo timestamp > conftest.file
+# Do `set' in a subshell so we don't clobber the current shell's
+# arguments. Must try -L first in case configure is actually a
+# symlink; some systems play weird games with the mod time of symlinks
+# (eg FreeBSD returns the mod time of the symlink's containing
+# directory).
+if (
+ set X `ls -Lt $srcdir/configure conftest.file 2> /dev/null`
+ if test "$[*]" = "X"; then
+ # -L didn't work.
+ set X `ls -t $srcdir/configure conftest.file`
+ fi
+ rm -f conftest.file
+ if test "$[*]" != "X $srcdir/configure conftest.file" \
+ && test "$[*]" != "X conftest.file $srcdir/configure"; then
+
+ # If neither matched, then we have a broken ls. This can happen
+ # if, for instance, CONFIG_SHELL is bash and it inherits a
+ # broken ls alias from the environment. This has actually
+ # happened. Such a system could not be considered "sane".
+ AC_MSG_ERROR([ls -t appears to fail. Make sure there is not a broken
+alias in your environment])
+ fi
+
+ test "$[2]" = conftest.file
+ )
+then
+ # Ok.
+ :
+else
+ AC_MSG_ERROR([newly created file is older than distributed files!
+Check your system clock])
+fi
+AC_MSG_RESULT(yes)])
+
+# -*- Autoconf -*-
+
+
+# Copyright 1997, 1999, 2000, 2001 Free Software Foundation, Inc.
+
+# This program is free software; you can redistribute it and/or modify
+# it under the terms of the GNU General Public License as published by
+# the Free Software Foundation; either version 2, or (at your option)
+# any later version.
+
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
+# GNU General Public License for more details.
+
+# You should have received a copy of the GNU General Public License
+# along with this program; if not, write to the Free Software
+# Foundation, Inc., 59 Temple Place - Suite 330, Boston, MA
+# 02111-1307, USA.
+
+# serial 3
+
+# AM_MISSING_PROG(NAME, PROGRAM)
+# ------------------------------
+AC_DEFUN([AM_MISSING_PROG],
+[AC_REQUIRE([AM_MISSING_HAS_RUN])
+$1=${$1-"${am_missing_run}$2"}
+AC_SUBST($1)])
+
+
+# AM_MISSING_HAS_RUN
+# ------------------
+# Define MISSING if not defined so far and test if it supports --run.
+# If it does, set am_missing_run to use it, otherwise, to nothing.
+AC_DEFUN([AM_MISSING_HAS_RUN],
+[AC_REQUIRE([AM_AUX_DIR_EXPAND])dnl
+test x"${MISSING+set}" = xset || MISSING="\${SHELL} $am_aux_dir/missing"
+# Use eval to expand $SHELL
+if eval "$MISSING --run true"; then
+ am_missing_run="$MISSING --run "
+else
+ am_missing_run=
+ AC_MSG_WARN([`missing' script is too old or missing])
+fi
+])
+
+# AM_AUX_DIR_EXPAND
+
+# Copyright 2001 Free Software Foundation, Inc.
+
+# This program is free software; you can redistribute it and/or modify
+# it under the terms of the GNU General Public License as published by
+# the Free Software Foundation; either version 2, or (at your option)
+# any later version.
+
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
+# GNU General Public License for more details.
+
+# You should have received a copy of the GNU General Public License
+# along with this program; if not, write to the Free Software
+# Foundation, Inc., 59 Temple Place - Suite 330, Boston, MA
+# 02111-1307, USA.
+
+# For projects using AC_CONFIG_AUX_DIR([foo]), Autoconf sets
+# $ac_aux_dir to `$srcdir/foo'. In other projects, it is set to
+# `$srcdir', `$srcdir/..', or `$srcdir/../..'.
+#
+# Of course, Automake must honor this variable whenever it calls a
+# tool from the auxiliary directory. The problem is that $srcdir (and
+# therefore $ac_aux_dir as well) can be either absolute or relative,
+# depending on how configure is run. This is pretty annoying, since
+# it makes $ac_aux_dir quite unusable in subdirectories: in the top
+# source directory, any form will work fine, but in subdirectories a
+# relative path needs to be adjusted first.
+#
+# $ac_aux_dir/missing
+# fails when called from a subdirectory if $ac_aux_dir is relative
+# $top_srcdir/$ac_aux_dir/missing
+# fails if $ac_aux_dir is absolute,
+# fails when called from a subdirectory in a VPATH build with
+# a relative $ac_aux_dir
+#
+# The reason of the latter failure is that $top_srcdir and $ac_aux_dir
+# are both prefixed by $srcdir. In an in-source build this is usually
+# harmless because $srcdir is `.', but things will broke when you
+# start a VPATH build or use an absolute $srcdir.
+#
+# So we could use something similar to $top_srcdir/$ac_aux_dir/missing,
+# iff we strip the leading $srcdir from $ac_aux_dir. That would be:
+# am_aux_dir='\$(top_srcdir)/'`expr "$ac_aux_dir" : "$srcdir//*\(.*\)"`
+# and then we would define $MISSING as
+# MISSING="\${SHELL} $am_aux_dir/missing"
+# This will work as long as MISSING is not called from configure, because
+# unfortunately $(top_srcdir) has no meaning in configure.
+# However there are other variables, like CC, which are often used in
+# configure, and could therefore not use this "fixed" $ac_aux_dir.
+#
+# Another solution, used here, is to always expand $ac_aux_dir to an
+# absolute PATH. The drawback is that using absolute paths prevent a
+# configured tree to be moved without reconfiguration.
+
+# Rely on autoconf to set up CDPATH properly.
+AC_PREREQ([2.50])
+
+AC_DEFUN([AM_AUX_DIR_EXPAND], [
+# expand $ac_aux_dir to an absolute path
+am_aux_dir=`cd $ac_aux_dir && pwd`
+])
+
+# AM_PROG_INSTALL_SH
+# ------------------
+# Define $install_sh.
+
+# Copyright 2001 Free Software Foundation, Inc.
+
+# This program is free software; you can redistribute it and/or modify
+# it under the terms of the GNU General Public License as published by
+# the Free Software Foundation; either version 2, or (at your option)
+# any later version.
+
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
+# GNU General Public License for more details.
+
+# You should have received a copy of the GNU General Public License
+# along with this program; if not, write to the Free Software
+# Foundation, Inc., 59 Temple Place - Suite 330, Boston, MA
+# 02111-1307, USA.
+
+AC_DEFUN([AM_PROG_INSTALL_SH],
+[AC_REQUIRE([AM_AUX_DIR_EXPAND])dnl
+install_sh=${install_sh-"$am_aux_dir/install-sh"}
+AC_SUBST(install_sh)])
+
+# AM_PROG_INSTALL_STRIP
+
+# Copyright 2001 Free Software Foundation, Inc.
+
+# This program is free software; you can redistribute it and/or modify
+# it under the terms of the GNU General Public License as published by
+# the Free Software Foundation; either version 2, or (at your option)
+# any later version.
+
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
+# GNU General Public License for more details.
+
+# You should have received a copy of the GNU General Public License
+# along with this program; if not, write to the Free Software
+# Foundation, Inc., 59 Temple Place - Suite 330, Boston, MA
+# 02111-1307, USA.
+
+# One issue with vendor `install' (even GNU) is that you can't
+# specify the program used to strip binaries. This is especially
+# annoying in cross-compiling environments, where the build's strip
+# is unlikely to handle the host's binaries.
+# Fortunately install-sh will honor a STRIPPROG variable, so we
+# always use install-sh in `make install-strip', and initialize
+# STRIPPROG with the value of the STRIP variable (set by the user).
+AC_DEFUN([AM_PROG_INSTALL_STRIP],
+[AC_REQUIRE([AM_PROG_INSTALL_SH])dnl
+# Installed binaries are usually stripped using `strip' when the user
+# run `make install-strip'. However `strip' might not be the right
+# tool to use in cross-compilation environments, therefore Automake
+# will honor the `STRIP' environment variable to overrule this program.
+dnl Don't test for $cross_compiling = yes, because it might be `maybe'.
+if test "$cross_compiling" != no; then
+ AC_CHECK_TOOL([STRIP], [strip], :)
+fi
+INSTALL_STRIP_PROGRAM="\${SHELL} \$(install_sh) -c -s"
+AC_SUBST([INSTALL_STRIP_PROGRAM])])
+
+# -*- Autoconf -*-
+# Copyright (C) 2003 Free Software Foundation, Inc.
+
+# This program is free software; you can redistribute it and/or modify
+# it under the terms of the GNU General Public License as published by
+# the Free Software Foundation; either version 2, or (at your option)
+# any later version.
+
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
+# GNU General Public License for more details.
+
+# You should have received a copy of the GNU General Public License
+# along with this program; if not, write to the Free Software
+# Foundation, Inc., 59 Temple Place - Suite 330, Boston, MA
+# 02111-1307, USA.
+
+# serial 1
+
+# Check whether the underlying file-system supports filenames
+# with a leading dot. For instance MS-DOS doesn't.
+AC_DEFUN([AM_SET_LEADING_DOT],
+[rm -rf .tst 2>/dev/null
+mkdir .tst 2>/dev/null
+if test -d .tst; then
+ am__leading_dot=.
+else
+ am__leading_dot=_
+fi
+rmdir .tst 2>/dev/null
+AC_SUBST([am__leading_dot])])
+
+# serial 5 -*- Autoconf -*-
+
+# Copyright (C) 1999, 2000, 2001, 2002, 2003 Free Software Foundation, Inc.
+
+# This program is free software; you can redistribute it and/or modify
+# it under the terms of the GNU General Public License as published by
+# the Free Software Foundation; either version 2, or (at your option)
+# any later version.
+
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
+# GNU General Public License for more details.
+
+# You should have received a copy of the GNU General Public License
+# along with this program; if not, write to the Free Software
+# Foundation, Inc., 59 Temple Place - Suite 330, Boston, MA
+# 02111-1307, USA.
+
+
+# There are a few dirty hacks below to avoid letting `AC_PROG_CC' be
+# written in clear, in which case automake, when reading aclocal.m4,
+# will think it sees a *use*, and therefore will trigger all it's
+# C support machinery. Also note that it means that autoscan, seeing
+# CC etc. in the Makefile, will ask for an AC_PROG_CC use...
+
+
+
+# _AM_DEPENDENCIES(NAME)
+# ----------------------
+# See how the compiler implements dependency checking.
+# NAME is "CC", "CXX", "GCJ", or "OBJC".
+# We try a few techniques and use that to set a single cache variable.
+#
+# We don't AC_REQUIRE the corresponding AC_PROG_CC since the latter was
+# modified to invoke _AM_DEPENDENCIES(CC); we would have a circular
+# dependency, and given that the user is not expected to run this macro,
+# just rely on AC_PROG_CC.
+AC_DEFUN([_AM_DEPENDENCIES],
+[AC_REQUIRE([AM_SET_DEPDIR])dnl
+AC_REQUIRE([AM_OUTPUT_DEPENDENCY_COMMANDS])dnl
+AC_REQUIRE([AM_MAKE_INCLUDE])dnl
+AC_REQUIRE([AM_DEP_TRACK])dnl
+
+ifelse([$1], CC, [depcc="$CC" am_compiler_list=],
+ [$1], CXX, [depcc="$CXX" am_compiler_list=],
+ [$1], OBJC, [depcc="$OBJC" am_compiler_list='gcc3 gcc'],
+ [$1], GCJ, [depcc="$GCJ" am_compiler_list='gcc3 gcc'],
+ [depcc="$$1" am_compiler_list=])
+
+AC_CACHE_CHECK([dependency style of $depcc],
+ [am_cv_$1_dependencies_compiler_type],
+[if test -z "$AMDEP_TRUE" && test -f "$am_depcomp"; then
+ # We make a subdir and do the tests there. Otherwise we can end up
+ # making bogus files that we don't know about and never remove. For
+ # instance it was reported that on HP-UX the gcc test will end up
+ # making a dummy file named `D' -- because `-MD' means `put the output
+ # in D'.
+ mkdir conftest.dir
+ # Copy depcomp to subdir because otherwise we won't find it if we're
+ # using a relative directory.
+ cp "$am_depcomp" conftest.dir
+ cd conftest.dir
+
+ am_cv_$1_dependencies_compiler_type=none
+ if test "$am_compiler_list" = ""; then
+ am_compiler_list=`sed -n ['s/^#*\([a-zA-Z0-9]*\))$/\1/p'] < ./depcomp`
+ fi
+ for depmode in $am_compiler_list; do
+ # We need to recreate these files for each test, as the compiler may
+ # overwrite some of them when testing with obscure command lines.
+ # This happens at least with the AIX C compiler.
+ echo '#include "conftest.h"' > conftest.c
+ echo 'int i;' > conftest.h
+ echo "${am__include} ${am__quote}conftest.Po${am__quote}" > confmf
+
+ case $depmode in
+ nosideeffect)
+ # after this tag, mechanisms are not by side-effect, so they'll
+ # only be used when explicitly requested
+ if test "x$enable_dependency_tracking" = xyes; then
+ continue
+ else
+ break
+ fi
+ ;;
+ none) break ;;
+ esac
+ # We check with `-c' and `-o' for the sake of the "dashmstdout"
+ # mode. It turns out that the SunPro C++ compiler does not properly
+ # handle `-M -o', and we need to detect this.
+ if depmode=$depmode \
+ source=conftest.c object=conftest.o \
+ depfile=conftest.Po tmpdepfile=conftest.TPo \
+ $SHELL ./depcomp $depcc -c -o conftest.o conftest.c \
+ >/dev/null 2>conftest.err &&
+ grep conftest.h conftest.Po > /dev/null 2>&1 &&
+ ${MAKE-make} -s -f confmf > /dev/null 2>&1; then
+ # icc doesn't choke on unknown options, it will just issue warnings
+ # (even with -Werror). So we grep stderr for any message
+ # that says an option was ignored.
+ if grep 'ignoring option' conftest.err >/dev/null 2>&1; then :; else
+ am_cv_$1_dependencies_compiler_type=$depmode
+ break
+ fi
+ fi
+ done
+
+ cd ..
+ rm -rf conftest.dir
+else
+ am_cv_$1_dependencies_compiler_type=none
+fi
+])
+AC_SUBST([$1DEPMODE], [depmode=$am_cv_$1_dependencies_compiler_type])
+AM_CONDITIONAL([am__fastdep$1], [
+ test "x$enable_dependency_tracking" != xno \
+ && test "$am_cv_$1_dependencies_compiler_type" = gcc3])
+])
+
+
+# AM_SET_DEPDIR
+# -------------
+# Choose a directory name for dependency files.
+# This macro is AC_REQUIREd in _AM_DEPENDENCIES
+AC_DEFUN([AM_SET_DEPDIR],
+[AC_REQUIRE([AM_SET_LEADING_DOT])dnl
+AC_SUBST([DEPDIR], ["${am__leading_dot}deps"])dnl
+])
+
+
+# AM_DEP_TRACK
+# ------------
+AC_DEFUN([AM_DEP_TRACK],
+[AC_ARG_ENABLE(dependency-tracking,
+[ --disable-dependency-tracking Speeds up one-time builds
+ --enable-dependency-tracking Do not reject slow dependency extractors])
+if test "x$enable_dependency_tracking" != xno; then
+ am_depcomp="$ac_aux_dir/depcomp"
+ AMDEPBACKSLASH='\'
+fi
+AM_CONDITIONAL([AMDEP], [test "x$enable_dependency_tracking" != xno])
+AC_SUBST([AMDEPBACKSLASH])
+])
+
+# Generate code to set up dependency tracking. -*- Autoconf -*-
+
+# Copyright 1999, 2000, 2001, 2002 Free Software Foundation, Inc.
+
+# This program is free software; you can redistribute it and/or modify
+# it under the terms of the GNU General Public License as published by
+# the Free Software Foundation; either version 2, or (at your option)
+# any later version.
+
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
+# GNU General Public License for more details.
+
+# You should have received a copy of the GNU General Public License
+# along with this program; if not, write to the Free Software
+# Foundation, Inc., 59 Temple Place - Suite 330, Boston, MA
+# 02111-1307, USA.
+
+#serial 2
+
+# _AM_OUTPUT_DEPENDENCY_COMMANDS
+# ------------------------------
+AC_DEFUN([_AM_OUTPUT_DEPENDENCY_COMMANDS],
+[for mf in $CONFIG_FILES; do
+ # Strip MF so we end up with the name of the file.
+ mf=`echo "$mf" | sed -e 's/:.*$//'`
+ # Check whether this is an Automake generated Makefile or not.
+ # We used to match only the files named `Makefile.in', but
+ # some people rename them; so instead we look at the file content.
+ # Grep'ing the first line is not enough: some people post-process
+ # each Makefile.in and add a new line on top of each file to say so.
+ # So let's grep whole file.
+ if grep '^#.*generated by automake' $mf > /dev/null 2>&1; then
+ dirpart=`AS_DIRNAME("$mf")`
+ else
+ continue
+ fi
+ grep '^DEP_FILES *= *[[^ @%:@]]' < "$mf" > /dev/null || continue
+ # Extract the definition of DEP_FILES from the Makefile without
+ # running `make'.
+ DEPDIR=`sed -n -e '/^DEPDIR = / s///p' < "$mf"`
+ test -z "$DEPDIR" && continue
+ # When using ansi2knr, U may be empty or an underscore; expand it
+ U=`sed -n -e '/^U = / s///p' < "$mf"`
+ test -d "$dirpart/$DEPDIR" || mkdir "$dirpart/$DEPDIR"
+ # We invoke sed twice because it is the simplest approach to
+ # changing $(DEPDIR) to its actual value in the expansion.
+ for file in `sed -n -e '
+ /^DEP_FILES = .*\\\\$/ {
+ s/^DEP_FILES = //
+ :loop
+ s/\\\\$//
+ p
+ n
+ /\\\\$/ b loop
+ p
+ }
+ /^DEP_FILES = / s/^DEP_FILES = //p' < "$mf" | \
+ sed -e 's/\$(DEPDIR)/'"$DEPDIR"'/g' -e 's/\$U/'"$U"'/g'`; do
+ # Make sure the directory exists.
+ test -f "$dirpart/$file" && continue
+ fdir=`AS_DIRNAME(["$file"])`
+ AS_MKDIR_P([$dirpart/$fdir])
+ # echo "creating $dirpart/$file"
+ echo '# dummy' > "$dirpart/$file"
+ done
+done
+])# _AM_OUTPUT_DEPENDENCY_COMMANDS
+
+
+# AM_OUTPUT_DEPENDENCY_COMMANDS
+# -----------------------------
+# This macro should only be invoked once -- use via AC_REQUIRE.
+#
+# This code is only required when automatic dependency tracking
+# is enabled. FIXME. This creates each `.P' file that we will
+# need in order to bootstrap the dependency handling code.
+AC_DEFUN([AM_OUTPUT_DEPENDENCY_COMMANDS],
+[AC_CONFIG_COMMANDS([depfiles],
+ [test x"$AMDEP_TRUE" != x"" || _AM_OUTPUT_DEPENDENCY_COMMANDS],
+ [AMDEP_TRUE="$AMDEP_TRUE" ac_aux_dir="$ac_aux_dir"])
+])
+
+# Check to see how 'make' treats includes. -*- Autoconf -*-
+
+# Copyright (C) 2001, 2002 Free Software Foundation, Inc.
+
+# This program is free software; you can redistribute it and/or modify
+# it under the terms of the GNU General Public License as published by
+# the Free Software Foundation; either version 2, or (at your option)
+# any later version.
+
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
+# GNU General Public License for more details.
+
+# You should have received a copy of the GNU General Public License
+# along with this program; if not, write to the Free Software
+# Foundation, Inc., 59 Temple Place - Suite 330, Boston, MA
+# 02111-1307, USA.
+
+# serial 2
+
+# AM_MAKE_INCLUDE()
+# -----------------
+# Check to see how make treats includes.
+AC_DEFUN([AM_MAKE_INCLUDE],
+[am_make=${MAKE-make}
+cat > confinc << 'END'
+doit:
+ @echo done
+END
+# If we don't find an include directive, just comment out the code.
+AC_MSG_CHECKING([for style of include used by $am_make])
+am__include="#"
+am__quote=
+_am_result=none
+# First try GNU make style include.
+echo "include confinc" > confmf
+# We grep out `Entering directory' and `Leaving directory'
+# messages which can occur if `w' ends up in MAKEFLAGS.
+# In particular we don't look at `^make:' because GNU make might
+# be invoked under some other name (usually "gmake"), in which
+# case it prints its new name instead of `make'.
+if test "`$am_make -s -f confmf 2> /dev/null | grep -v 'ing directory'`" = "done"; then
+ am__include=include
+ am__quote=
+ _am_result=GNU
+fi
+# Now try BSD make style include.
+if test "$am__include" = "#"; then
+ echo '.include "confinc"' > confmf
+ if test "`$am_make -s -f confmf 2> /dev/null`" = "done"; then
+ am__include=.include
+ am__quote="\""
+ _am_result=BSD
+ fi
+fi
+AC_SUBST(am__include)
+AC_SUBST(am__quote)
+AC_MSG_RESULT($_am_result)
+rm -f confinc confmf
+])
+
+# AM_CONDITIONAL -*- Autoconf -*-
+
+# Copyright 1997, 2000, 2001 Free Software Foundation, Inc.
+
+# This program is free software; you can redistribute it and/or modify
+# it under the terms of the GNU General Public License as published by
+# the Free Software Foundation; either version 2, or (at your option)
+# any later version.
+
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
+# GNU General Public License for more details.
+
+# You should have received a copy of the GNU General Public License
+# along with this program; if not, write to the Free Software
+# Foundation, Inc., 59 Temple Place - Suite 330, Boston, MA
+# 02111-1307, USA.
+
+# serial 5
+
+AC_PREREQ(2.52)
+
+# AM_CONDITIONAL(NAME, SHELL-CONDITION)
+# -------------------------------------
+# Define a conditional.
+AC_DEFUN([AM_CONDITIONAL],
+[ifelse([$1], [TRUE], [AC_FATAL([$0: invalid condition: $1])],
+ [$1], [FALSE], [AC_FATAL([$0: invalid condition: $1])])dnl
+AC_SUBST([$1_TRUE])
+AC_SUBST([$1_FALSE])
+if $2; then
+ $1_TRUE=
+ $1_FALSE='#'
+else
+ $1_TRUE='#'
+ $1_FALSE=
+fi
+AC_CONFIG_COMMANDS_PRE(
+[if test -z "${$1_TRUE}" && test -z "${$1_FALSE}"; then
+ AC_MSG_ERROR([conditional "$1" was never defined.
+Usually this means the macro was only invoked conditionally.])
+fi])])
+
+# Like AC_CONFIG_HEADER, but automatically create stamp file. -*- Autoconf -*-
+
+# Copyright 1996, 1997, 2000, 2001 Free Software Foundation, Inc.
+
+# This program is free software; you can redistribute it and/or modify
+# it under the terms of the GNU General Public License as published by
+# the Free Software Foundation; either version 2, or (at your option)
+# any later version.
+
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
+# GNU General Public License for more details.
+
+# You should have received a copy of the GNU General Public License
+# along with this program; if not, write to the Free Software
+# Foundation, Inc., 59 Temple Place - Suite 330, Boston, MA
+# 02111-1307, USA.
+
+AC_PREREQ([2.52])
+
+# serial 6
+
+# AM_CONFIG_HEADER is obsolete. It has been replaced by AC_CONFIG_HEADERS.
+AU_DEFUN([AM_CONFIG_HEADER], [AC_CONFIG_HEADERS($@)])
+
Added: trunk/packages/rnahybrid/branches/upstream/current/config.guess
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/config.guess (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/config.guess 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,1354 @@
+#! /bin/sh
+# Attempt to guess a canonical system name.
+# Copyright (C) 1992, 1993, 1994, 1995, 1996, 1997, 1998, 1999,
+# 2000, 2001, 2002 Free Software Foundation, Inc.
+
+timestamp='2002-07-23'
+
+# This file is free software; you can redistribute it and/or modify it
+# under the terms of the GNU General Public License as published by
+# the Free Software Foundation; either version 2 of the License, or
+# (at your option) any later version.
+#
+# This program is distributed in the hope that it will be useful, but
+# WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU
+# General Public License for more details.
+#
+# You should have received a copy of the GNU General Public License
+# along with this program; if not, write to the Free Software
+# Foundation, Inc., 59 Temple Place - Suite 330, Boston, MA 02111-1307, USA.
+#
+# As a special exception to the GNU General Public License, if you
+# distribute this file as part of a program that contains a
+# configuration script generated by Autoconf, you may include it under
+# the same distribution terms that you use for the rest of that program.
+
+# Originally written by Per Bothner <per at bothner.com>.
+# Please send patches to <config-patches at gnu.org>. Submit a context
+# diff and a properly formatted ChangeLog entry.
+#
+# This script attempts to guess a canonical system name similar to
+# config.sub. If it succeeds, it prints the system name on stdout, and
+# exits with 0. Otherwise, it exits with 1.
+#
+# The plan is that this can be called by configure scripts if you
+# don't specify an explicit build system type.
+
+me=`echo "$0" | sed -e 's,.*/,,'`
+
+usage="\
+Usage: $0 [OPTION]
+
+Output the configuration name of the system \`$me' is run on.
+
+Operation modes:
+ -h, --help print this help, then exit
+ -t, --time-stamp print date of last modification, then exit
+ -v, --version print version number, then exit
+
+Report bugs and patches to <config-patches at gnu.org>."
+
+version="\
+GNU config.guess ($timestamp)
+
+Originally written by Per Bothner.
+Copyright (C) 1992, 1993, 1994, 1995, 1996, 1997, 1998, 1999, 2000, 2001
+Free Software Foundation, Inc.
+
+This is free software; see the source for copying conditions. There is NO
+warranty; not even for MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE."
+
+help="
+Try \`$me --help' for more information."
+
+# Parse command line
+while test $# -gt 0 ; do
+ case $1 in
+ --time-stamp | --time* | -t )
+ echo "$timestamp" ; exit 0 ;;
+ --version | -v )
+ echo "$version" ; exit 0 ;;
+ --help | --h* | -h )
+ echo "$usage"; exit 0 ;;
+ -- ) # Stop option processing
+ shift; break ;;
+ - ) # Use stdin as input.
+ break ;;
+ -* )
+ echo "$me: invalid option $1$help" >&2
+ exit 1 ;;
+ * )
+ break ;;
+ esac
+done
+
+if test $# != 0; then
+ echo "$me: too many arguments$help" >&2
+ exit 1
+fi
+
+trap 'exit 1' 1 2 15
+
+# CC_FOR_BUILD -- compiler used by this script. Note that the use of a
+# compiler to aid in system detection is discouraged as it requires
+# temporary files to be created and, as you can see below, it is a
+# headache to deal with in a portable fashion.
+
+# Historically, `CC_FOR_BUILD' used to be named `HOST_CC'. We still
+# use `HOST_CC' if defined, but it is deprecated.
+
+# This shell variable is my proudest work .. or something. --bje
+
+set_cc_for_build='tmpdir=${TMPDIR-/tmp}/config-guess-$$ ;
+(old=`umask` && umask 077 && mkdir $tmpdir && umask $old && unset old)
+ || (echo "$me: cannot create $tmpdir" >&2 && exit 1) ;
+dummy=$tmpdir/dummy ;
+files="$dummy.c $dummy.o $dummy.rel $dummy" ;
+trap '"'"'rm -f $files; rmdir $tmpdir; exit 1'"'"' 1 2 15 ;
+case $CC_FOR_BUILD,$HOST_CC,$CC in
+ ,,) echo "int x;" > $dummy.c ;
+ for c in cc gcc c89 c99 ; do
+ if ($c $dummy.c -c -o $dummy.o) >/dev/null 2>&1 ; then
+ CC_FOR_BUILD="$c"; break ;
+ fi ;
+ done ;
+ rm -f $files ;
+ if test x"$CC_FOR_BUILD" = x ; then
+ CC_FOR_BUILD=no_compiler_found ;
+ fi
+ ;;
+ ,,*) CC_FOR_BUILD=$CC ;;
+ ,*,*) CC_FOR_BUILD=$HOST_CC ;;
+esac ;
+unset files'
+
+# This is needed to find uname on a Pyramid OSx when run in the BSD universe.
+# (ghazi at noc.rutgers.edu 1994-08-24)
+if (test -f /.attbin/uname) >/dev/null 2>&1 ; then
+ PATH=$PATH:/.attbin ; export PATH
+fi
+
+UNAME_MACHINE=`(uname -m) 2>/dev/null` || UNAME_MACHINE=unknown
+UNAME_RELEASE=`(uname -r) 2>/dev/null` || UNAME_RELEASE=unknown
+UNAME_SYSTEM=`(uname -s) 2>/dev/null` || UNAME_SYSTEM=unknown
+UNAME_VERSION=`(uname -v) 2>/dev/null` || UNAME_VERSION=unknown
+
+# Note: order is significant - the case branches are not exclusive.
+
+case "${UNAME_MACHINE}:${UNAME_SYSTEM}:${UNAME_RELEASE}:${UNAME_VERSION}" in
+ *:NetBSD:*:*)
+ # NetBSD (nbsd) targets should (where applicable) match one or
+ # more of the tupples: *-*-netbsdelf*, *-*-netbsdaout*,
+ # *-*-netbsdecoff* and *-*-netbsd*. For targets that recently
+ # switched to ELF, *-*-netbsd* would select the old
+ # object file format. This provides both forward
+ # compatibility and a consistent mechanism for selecting the
+ # object file format.
+ #
+ # Note: NetBSD doesn't particularly care about the vendor
+ # portion of the name. We always set it to "unknown".
+ sysctl="sysctl -n hw.machine_arch"
+ UNAME_MACHINE_ARCH=`(/sbin/$sysctl 2>/dev/null || \
+ /usr/sbin/$sysctl 2>/dev/null || echo unknown)`
+ case "${UNAME_MACHINE_ARCH}" in
+ armeb) machine=armeb-unknown ;;
+ arm*) machine=arm-unknown ;;
+ sh3el) machine=shl-unknown ;;
+ sh3eb) machine=sh-unknown ;;
+ *) machine=${UNAME_MACHINE_ARCH}-unknown ;;
+ esac
+ # The Operating System including object format, if it has switched
+ # to ELF recently, or will in the future.
+ case "${UNAME_MACHINE_ARCH}" in
+ arm*|i386|m68k|ns32k|sh3*|sparc|vax)
+ eval $set_cc_for_build
+ if echo __ELF__ | $CC_FOR_BUILD -E - 2>/dev/null \
+ | grep __ELF__ >/dev/null
+ then
+ # Once all utilities can be ECOFF (netbsdecoff) or a.out (netbsdaout).
+ # Return netbsd for either. FIX?
+ os=netbsd
+ else
+ os=netbsdelf
+ fi
+ ;;
+ *)
+ os=netbsd
+ ;;
+ esac
+ # The OS release
+ release=`echo ${UNAME_RELEASE}|sed -e 's/[-_].*/\./'`
+ # Since CPU_TYPE-MANUFACTURER-KERNEL-OPERATING_SYSTEM:
+ # contains redundant information, the shorter form:
+ # CPU_TYPE-MANUFACTURER-OPERATING_SYSTEM is used.
+ echo "${machine}-${os}${release}"
+ exit 0 ;;
+ amiga:OpenBSD:*:*)
+ echo m68k-unknown-openbsd${UNAME_RELEASE}
+ exit 0 ;;
+ arc:OpenBSD:*:*)
+ echo mipsel-unknown-openbsd${UNAME_RELEASE}
+ exit 0 ;;
+ hp300:OpenBSD:*:*)
+ echo m68k-unknown-openbsd${UNAME_RELEASE}
+ exit 0 ;;
+ mac68k:OpenBSD:*:*)
+ echo m68k-unknown-openbsd${UNAME_RELEASE}
+ exit 0 ;;
+ macppc:OpenBSD:*:*)
+ echo powerpc-unknown-openbsd${UNAME_RELEASE}
+ exit 0 ;;
+ mvme68k:OpenBSD:*:*)
+ echo m68k-unknown-openbsd${UNAME_RELEASE}
+ exit 0 ;;
+ mvme88k:OpenBSD:*:*)
+ echo m88k-unknown-openbsd${UNAME_RELEASE}
+ exit 0 ;;
+ mvmeppc:OpenBSD:*:*)
+ echo powerpc-unknown-openbsd${UNAME_RELEASE}
+ exit 0 ;;
+ pmax:OpenBSD:*:*)
+ echo mipsel-unknown-openbsd${UNAME_RELEASE}
+ exit 0 ;;
+ sgi:OpenBSD:*:*)
+ echo mipseb-unknown-openbsd${UNAME_RELEASE}
+ exit 0 ;;
+ sun3:OpenBSD:*:*)
+ echo m68k-unknown-openbsd${UNAME_RELEASE}
+ exit 0 ;;
+ wgrisc:OpenBSD:*:*)
+ echo mipsel-unknown-openbsd${UNAME_RELEASE}
+ exit 0 ;;
+ *:OpenBSD:*:*)
+ echo ${UNAME_MACHINE}-unknown-openbsd${UNAME_RELEASE}
+ exit 0 ;;
+ alpha:OSF1:*:*)
+ if test $UNAME_RELEASE = "V4.0"; then
+ UNAME_RELEASE=`/usr/sbin/sizer -v | awk '{print $3}'`
+ fi
+ # A Vn.n version is a released version.
+ # A Tn.n version is a released field test version.
+ # A Xn.n version is an unreleased experimental baselevel.
+ # 1.2 uses "1.2" for uname -r.
+ eval $set_cc_for_build
+ cat <<EOF >$dummy.s
+ .data
+\$Lformat:
+ .byte 37,100,45,37,120,10,0 # "%d-%x\n"
+
+ .text
+ .globl main
+ .align 4
+ .ent main
+main:
+ .frame \$30,16,\$26,0
+ ldgp \$29,0(\$27)
+ .prologue 1
+ .long 0x47e03d80 # implver \$0
+ lda \$2,-1
+ .long 0x47e20c21 # amask \$2,\$1
+ lda \$16,\$Lformat
+ mov \$0,\$17
+ not \$1,\$18
+ jsr \$26,printf
+ ldgp \$29,0(\$26)
+ mov 0,\$16
+ jsr \$26,exit
+ .end main
+EOF
+ $CC_FOR_BUILD $dummy.s -o $dummy 2>/dev/null
+ if test "$?" = 0 ; then
+ case `$dummy` in
+ 0-0)
+ UNAME_MACHINE="alpha"
+ ;;
+ 1-0)
+ UNAME_MACHINE="alphaev5"
+ ;;
+ 1-1)
+ UNAME_MACHINE="alphaev56"
+ ;;
+ 1-101)
+ UNAME_MACHINE="alphapca56"
+ ;;
+ 2-303)
+ UNAME_MACHINE="alphaev6"
+ ;;
+ 2-307)
+ UNAME_MACHINE="alphaev67"
+ ;;
+ 2-1307)
+ UNAME_MACHINE="alphaev68"
+ ;;
+ 3-1307)
+ UNAME_MACHINE="alphaev7"
+ ;;
+ esac
+ fi
+ rm -f $dummy.s $dummy && rmdir $tmpdir
+ echo ${UNAME_MACHINE}-dec-osf`echo ${UNAME_RELEASE} | sed -e 's/^[VTX]//' | tr 'ABCDEFGHIJKLMNOPQRSTUVWXYZ' 'abcdefghijklmnopqrstuvwxyz'`
+ exit 0 ;;
+ Alpha\ *:Windows_NT*:*)
+ # How do we know it's Interix rather than the generic POSIX subsystem?
+ # Should we change UNAME_MACHINE based on the output of uname instead
+ # of the specific Alpha model?
+ echo alpha-pc-interix
+ exit 0 ;;
+ 21064:Windows_NT:50:3)
+ echo alpha-dec-winnt3.5
+ exit 0 ;;
+ Amiga*:UNIX_System_V:4.0:*)
+ echo m68k-unknown-sysv4
+ exit 0;;
+ *:[Aa]miga[Oo][Ss]:*:*)
+ echo ${UNAME_MACHINE}-unknown-amigaos
+ exit 0 ;;
+ *:[Mm]orph[Oo][Ss]:*:*)
+ echo ${UNAME_MACHINE}-unknown-morphos
+ exit 0 ;;
+ *:OS/390:*:*)
+ echo i370-ibm-openedition
+ exit 0 ;;
+ arm:RISC*:1.[012]*:*|arm:riscix:1.[012]*:*)
+ echo arm-acorn-riscix${UNAME_RELEASE}
+ exit 0;;
+ SR2?01:HI-UX/MPP:*:* | SR8000:HI-UX/MPP:*:*)
+ echo hppa1.1-hitachi-hiuxmpp
+ exit 0;;
+ Pyramid*:OSx*:*:* | MIS*:OSx*:*:* | MIS*:SMP_DC-OSx*:*:*)
+ # akee at wpdis03.wpafb.af.mil (Earle F. Ake) contributed MIS and NILE.
+ if test "`(/bin/universe) 2>/dev/null`" = att ; then
+ echo pyramid-pyramid-sysv3
+ else
+ echo pyramid-pyramid-bsd
+ fi
+ exit 0 ;;
+ NILE*:*:*:dcosx)
+ echo pyramid-pyramid-svr4
+ exit 0 ;;
+ DRS?6000:UNIX_SV:4.2*:7*)
+ case `/usr/bin/uname -p` in
+ sparc) echo sparc-icl-nx7 && exit 0 ;;
+ esac ;;
+ sun4H:SunOS:5.*:*)
+ echo sparc-hal-solaris2`echo ${UNAME_RELEASE}|sed -e 's/[^.]*//'`
+ exit 0 ;;
+ sun4*:SunOS:5.*:* | tadpole*:SunOS:5.*:*)
+ echo sparc-sun-solaris2`echo ${UNAME_RELEASE}|sed -e 's/[^.]*//'`
+ exit 0 ;;
+ i86pc:SunOS:5.*:*)
+ echo i386-pc-solaris2`echo ${UNAME_RELEASE}|sed -e 's/[^.]*//'`
+ exit 0 ;;
+ sun4*:SunOS:6*:*)
+ # According to config.sub, this is the proper way to canonicalize
+ # SunOS6. Hard to guess exactly what SunOS6 will be like, but
+ # it's likely to be more like Solaris than SunOS4.
+ echo sparc-sun-solaris3`echo ${UNAME_RELEASE}|sed -e 's/[^.]*//'`
+ exit 0 ;;
+ sun4*:SunOS:*:*)
+ case "`/usr/bin/arch -k`" in
+ Series*|S4*)
+ UNAME_RELEASE=`uname -v`
+ ;;
+ esac
+ # Japanese Language versions have a version number like `4.1.3-JL'.
+ echo sparc-sun-sunos`echo ${UNAME_RELEASE}|sed -e 's/-/_/'`
+ exit 0 ;;
+ sun3*:SunOS:*:*)
+ echo m68k-sun-sunos${UNAME_RELEASE}
+ exit 0 ;;
+ sun*:*:4.2BSD:*)
+ UNAME_RELEASE=`(sed 1q /etc/motd | awk '{print substr($5,1,3)}') 2>/dev/null`
+ test "x${UNAME_RELEASE}" = "x" && UNAME_RELEASE=3
+ case "`/bin/arch`" in
+ sun3)
+ echo m68k-sun-sunos${UNAME_RELEASE}
+ ;;
+ sun4)
+ echo sparc-sun-sunos${UNAME_RELEASE}
+ ;;
+ esac
+ exit 0 ;;
+ aushp:SunOS:*:*)
+ echo sparc-auspex-sunos${UNAME_RELEASE}
+ exit 0 ;;
+ # The situation for MiNT is a little confusing. The machine name
+ # can be virtually everything (everything which is not
+ # "atarist" or "atariste" at least should have a processor
+ # > m68000). The system name ranges from "MiNT" over "FreeMiNT"
+ # to the lowercase version "mint" (or "freemint"). Finally
+ # the system name "TOS" denotes a system which is actually not
+ # MiNT. But MiNT is downward compatible to TOS, so this should
+ # be no problem.
+ atarist[e]:*MiNT:*:* | atarist[e]:*mint:*:* | atarist[e]:*TOS:*:*)
+ echo m68k-atari-mint${UNAME_RELEASE}
+ exit 0 ;;
+ atari*:*MiNT:*:* | atari*:*mint:*:* | atarist[e]:*TOS:*:*)
+ echo m68k-atari-mint${UNAME_RELEASE}
+ exit 0 ;;
+ *falcon*:*MiNT:*:* | *falcon*:*mint:*:* | *falcon*:*TOS:*:*)
+ echo m68k-atari-mint${UNAME_RELEASE}
+ exit 0 ;;
+ milan*:*MiNT:*:* | milan*:*mint:*:* | *milan*:*TOS:*:*)
+ echo m68k-milan-mint${UNAME_RELEASE}
+ exit 0 ;;
+ hades*:*MiNT:*:* | hades*:*mint:*:* | *hades*:*TOS:*:*)
+ echo m68k-hades-mint${UNAME_RELEASE}
+ exit 0 ;;
+ *:*MiNT:*:* | *:*mint:*:* | *:*TOS:*:*)
+ echo m68k-unknown-mint${UNAME_RELEASE}
+ exit 0 ;;
+ powerpc:machten:*:*)
+ echo powerpc-apple-machten${UNAME_RELEASE}
+ exit 0 ;;
+ RISC*:Mach:*:*)
+ echo mips-dec-mach_bsd4.3
+ exit 0 ;;
+ RISC*:ULTRIX:*:*)
+ echo mips-dec-ultrix${UNAME_RELEASE}
+ exit 0 ;;
+ VAX*:ULTRIX*:*:*)
+ echo vax-dec-ultrix${UNAME_RELEASE}
+ exit 0 ;;
+ 2020:CLIX:*:* | 2430:CLIX:*:*)
+ echo clipper-intergraph-clix${UNAME_RELEASE}
+ exit 0 ;;
+ mips:*:*:UMIPS | mips:*:*:RISCos)
+ eval $set_cc_for_build
+ sed 's/^ //' << EOF >$dummy.c
+#ifdef __cplusplus
+#include <stdio.h> /* for printf() prototype */
+ int main (int argc, char *argv[]) {
+#else
+ int main (argc, argv) int argc; char *argv[]; {
+#endif
+ #if defined (host_mips) && defined (MIPSEB)
+ #if defined (SYSTYPE_SYSV)
+ printf ("mips-mips-riscos%ssysv\n", argv[1]); exit (0);
+ #endif
+ #if defined (SYSTYPE_SVR4)
+ printf ("mips-mips-riscos%ssvr4\n", argv[1]); exit (0);
+ #endif
+ #if defined (SYSTYPE_BSD43) || defined(SYSTYPE_BSD)
+ printf ("mips-mips-riscos%sbsd\n", argv[1]); exit (0);
+ #endif
+ #endif
+ exit (-1);
+ }
+EOF
+ $CC_FOR_BUILD $dummy.c -o $dummy \
+ && $dummy `echo "${UNAME_RELEASE}" | sed -n 's/\([0-9]*\).*/\1/p'` \
+ && rm -f $dummy.c $dummy && rmdir $tmpdir && exit 0
+ rm -f $dummy.c $dummy && rmdir $tmpdir
+ echo mips-mips-riscos${UNAME_RELEASE}
+ exit 0 ;;
+ Motorola:PowerMAX_OS:*:*)
+ echo powerpc-motorola-powermax
+ exit 0 ;;
+ Night_Hawk:*:*:PowerMAX_OS)
+ echo powerpc-harris-powermax
+ exit 0 ;;
+ Night_Hawk:Power_UNIX:*:*)
+ echo powerpc-harris-powerunix
+ exit 0 ;;
+ m88k:CX/UX:7*:*)
+ echo m88k-harris-cxux7
+ exit 0 ;;
+ m88k:*:4*:R4*)
+ echo m88k-motorola-sysv4
+ exit 0 ;;
+ m88k:*:3*:R3*)
+ echo m88k-motorola-sysv3
+ exit 0 ;;
+ AViiON:dgux:*:*)
+ # DG/UX returns AViiON for all architectures
+ UNAME_PROCESSOR=`/usr/bin/uname -p`
+ if [ $UNAME_PROCESSOR = mc88100 ] || [ $UNAME_PROCESSOR = mc88110 ]
+ then
+ if [ ${TARGET_BINARY_INTERFACE}x = m88kdguxelfx ] || \
+ [ ${TARGET_BINARY_INTERFACE}x = x ]
+ then
+ echo m88k-dg-dgux${UNAME_RELEASE}
+ else
+ echo m88k-dg-dguxbcs${UNAME_RELEASE}
+ fi
+ else
+ echo i586-dg-dgux${UNAME_RELEASE}
+ fi
+ exit 0 ;;
+ M88*:DolphinOS:*:*) # DolphinOS (SVR3)
+ echo m88k-dolphin-sysv3
+ exit 0 ;;
+ M88*:*:R3*:*)
+ # Delta 88k system running SVR3
+ echo m88k-motorola-sysv3
+ exit 0 ;;
+ XD88*:*:*:*) # Tektronix XD88 system running UTekV (SVR3)
+ echo m88k-tektronix-sysv3
+ exit 0 ;;
+ Tek43[0-9][0-9]:UTek:*:*) # Tektronix 4300 system running UTek (BSD)
+ echo m68k-tektronix-bsd
+ exit 0 ;;
+ *:IRIX*:*:*)
+ echo mips-sgi-irix`echo ${UNAME_RELEASE}|sed -e 's/-/_/g'`
+ exit 0 ;;
+ ????????:AIX?:[12].1:2) # AIX 2.2.1 or AIX 2.1.1 is RT/PC AIX.
+ echo romp-ibm-aix # uname -m gives an 8 hex-code CPU id
+ exit 0 ;; # Note that: echo "'`uname -s`'" gives 'AIX '
+ i*86:AIX:*:*)
+ echo i386-ibm-aix
+ exit 0 ;;
+ ia64:AIX:*:*)
+ if [ -x /usr/bin/oslevel ] ; then
+ IBM_REV=`/usr/bin/oslevel`
+ else
+ IBM_REV=${UNAME_VERSION}.${UNAME_RELEASE}
+ fi
+ echo ${UNAME_MACHINE}-ibm-aix${IBM_REV}
+ exit 0 ;;
+ *:AIX:2:3)
+ if grep bos325 /usr/include/stdio.h >/dev/null 2>&1; then
+ eval $set_cc_for_build
+ sed 's/^ //' << EOF >$dummy.c
+ #include <sys/systemcfg.h>
+
+ main()
+ {
+ if (!__power_pc())
+ exit(1);
+ puts("powerpc-ibm-aix3.2.5");
+ exit(0);
+ }
+EOF
+ $CC_FOR_BUILD $dummy.c -o $dummy && $dummy && rm -f $dummy.c $dummy && rmdir $tmpdir && exit 0
+ rm -f $dummy.c $dummy && rmdir $tmpdir
+ echo rs6000-ibm-aix3.2.5
+ elif grep bos324 /usr/include/stdio.h >/dev/null 2>&1; then
+ echo rs6000-ibm-aix3.2.4
+ else
+ echo rs6000-ibm-aix3.2
+ fi
+ exit 0 ;;
+ *:AIX:*:[45])
+ IBM_CPU_ID=`/usr/sbin/lsdev -C -c processor -S available | sed 1q | awk '{ print $1 }'`
+ if /usr/sbin/lsattr -El ${IBM_CPU_ID} | grep ' POWER' >/dev/null 2>&1; then
+ IBM_ARCH=rs6000
+ else
+ IBM_ARCH=powerpc
+ fi
+ if [ -x /usr/bin/oslevel ] ; then
+ IBM_REV=`/usr/bin/oslevel`
+ else
+ IBM_REV=${UNAME_VERSION}.${UNAME_RELEASE}
+ fi
+ echo ${IBM_ARCH}-ibm-aix${IBM_REV}
+ exit 0 ;;
+ *:AIX:*:*)
+ echo rs6000-ibm-aix
+ exit 0 ;;
+ ibmrt:4.4BSD:*|romp-ibm:BSD:*)
+ echo romp-ibm-bsd4.4
+ exit 0 ;;
+ ibmrt:*BSD:*|romp-ibm:BSD:*) # covers RT/PC BSD and
+ echo romp-ibm-bsd${UNAME_RELEASE} # 4.3 with uname added to
+ exit 0 ;; # report: romp-ibm BSD 4.3
+ *:BOSX:*:*)
+ echo rs6000-bull-bosx
+ exit 0 ;;
+ DPX/2?00:B.O.S.:*:*)
+ echo m68k-bull-sysv3
+ exit 0 ;;
+ 9000/[34]??:4.3bsd:1.*:*)
+ echo m68k-hp-bsd
+ exit 0 ;;
+ hp300:4.4BSD:*:* | 9000/[34]??:4.3bsd:2.*:*)
+ echo m68k-hp-bsd4.4
+ exit 0 ;;
+ 9000/[34678]??:HP-UX:*:*)
+ HPUX_REV=`echo ${UNAME_RELEASE}|sed -e 's/[^.]*.[0B]*//'`
+ case "${UNAME_MACHINE}" in
+ 9000/31? ) HP_ARCH=m68000 ;;
+ 9000/[34]?? ) HP_ARCH=m68k ;;
+ 9000/[678][0-9][0-9])
+ if [ -x /usr/bin/getconf ]; then
+ sc_cpu_version=`/usr/bin/getconf SC_CPU_VERSION 2>/dev/null`
+ sc_kernel_bits=`/usr/bin/getconf SC_KERNEL_BITS 2>/dev/null`
+ case "${sc_cpu_version}" in
+ 523) HP_ARCH="hppa1.0" ;; # CPU_PA_RISC1_0
+ 528) HP_ARCH="hppa1.1" ;; # CPU_PA_RISC1_1
+ 532) # CPU_PA_RISC2_0
+ case "${sc_kernel_bits}" in
+ 32) HP_ARCH="hppa2.0n" ;;
+ 64) HP_ARCH="hppa2.0w" ;;
+ '') HP_ARCH="hppa2.0" ;; # HP-UX 10.20
+ esac ;;
+ esac
+ fi
+ if [ "${HP_ARCH}" = "" ]; then
+ eval $set_cc_for_build
+ sed 's/^ //' << EOF >$dummy.c
+
+ #define _HPUX_SOURCE
+ #include <stdlib.h>
+ #include <unistd.h>
+
+ int main ()
+ {
+ #if defined(_SC_KERNEL_BITS)
+ long bits = sysconf(_SC_KERNEL_BITS);
+ #endif
+ long cpu = sysconf (_SC_CPU_VERSION);
+
+ switch (cpu)
+ {
+ case CPU_PA_RISC1_0: puts ("hppa1.0"); break;
+ case CPU_PA_RISC1_1: puts ("hppa1.1"); break;
+ case CPU_PA_RISC2_0:
+ #if defined(_SC_KERNEL_BITS)
+ switch (bits)
+ {
+ case 64: puts ("hppa2.0w"); break;
+ case 32: puts ("hppa2.0n"); break;
+ default: puts ("hppa2.0"); break;
+ } break;
+ #else /* !defined(_SC_KERNEL_BITS) */
+ puts ("hppa2.0"); break;
+ #endif
+ default: puts ("hppa1.0"); break;
+ }
+ exit (0);
+ }
+EOF
+ (CCOPTS= $CC_FOR_BUILD $dummy.c -o $dummy 2>/dev/null) && HP_ARCH=`$dummy`
+ if test -z "$HP_ARCH"; then HP_ARCH=hppa; fi
+ rm -f $dummy.c $dummy && rmdir $tmpdir
+ fi ;;
+ esac
+ echo ${HP_ARCH}-hp-hpux${HPUX_REV}
+ exit 0 ;;
+ ia64:HP-UX:*:*)
+ HPUX_REV=`echo ${UNAME_RELEASE}|sed -e 's/[^.]*.[0B]*//'`
+ echo ia64-hp-hpux${HPUX_REV}
+ exit 0 ;;
+ 3050*:HI-UX:*:*)
+ eval $set_cc_for_build
+ sed 's/^ //' << EOF >$dummy.c
+ #include <unistd.h>
+ int
+ main ()
+ {
+ long cpu = sysconf (_SC_CPU_VERSION);
+ /* The order matters, because CPU_IS_HP_MC68K erroneously returns
+ true for CPU_PA_RISC1_0. CPU_IS_PA_RISC returns correct
+ results, however. */
+ if (CPU_IS_PA_RISC (cpu))
+ {
+ switch (cpu)
+ {
+ case CPU_PA_RISC1_0: puts ("hppa1.0-hitachi-hiuxwe2"); break;
+ case CPU_PA_RISC1_1: puts ("hppa1.1-hitachi-hiuxwe2"); break;
+ case CPU_PA_RISC2_0: puts ("hppa2.0-hitachi-hiuxwe2"); break;
+ default: puts ("hppa-hitachi-hiuxwe2"); break;
+ }
+ }
+ else if (CPU_IS_HP_MC68K (cpu))
+ puts ("m68k-hitachi-hiuxwe2");
+ else puts ("unknown-hitachi-hiuxwe2");
+ exit (0);
+ }
+EOF
+ $CC_FOR_BUILD $dummy.c -o $dummy && $dummy && rm -f $dummy.c $dummy && rmdir $tmpdir && exit 0
+ rm -f $dummy.c $dummy && rmdir $tmpdir
+ echo unknown-hitachi-hiuxwe2
+ exit 0 ;;
+ 9000/7??:4.3bsd:*:* | 9000/8?[79]:4.3bsd:*:* )
+ echo hppa1.1-hp-bsd
+ exit 0 ;;
+ 9000/8??:4.3bsd:*:*)
+ echo hppa1.0-hp-bsd
+ exit 0 ;;
+ *9??*:MPE/iX:*:* | *3000*:MPE/iX:*:*)
+ echo hppa1.0-hp-mpeix
+ exit 0 ;;
+ hp7??:OSF1:*:* | hp8?[79]:OSF1:*:* )
+ echo hppa1.1-hp-osf
+ exit 0 ;;
+ hp8??:OSF1:*:*)
+ echo hppa1.0-hp-osf
+ exit 0 ;;
+ i*86:OSF1:*:*)
+ if [ -x /usr/sbin/sysversion ] ; then
+ echo ${UNAME_MACHINE}-unknown-osf1mk
+ else
+ echo ${UNAME_MACHINE}-unknown-osf1
+ fi
+ exit 0 ;;
+ parisc*:Lites*:*:*)
+ echo hppa1.1-hp-lites
+ exit 0 ;;
+ C1*:ConvexOS:*:* | convex:ConvexOS:C1*:*)
+ echo c1-convex-bsd
+ exit 0 ;;
+ C2*:ConvexOS:*:* | convex:ConvexOS:C2*:*)
+ if getsysinfo -f scalar_acc
+ then echo c32-convex-bsd
+ else echo c2-convex-bsd
+ fi
+ exit 0 ;;
+ C34*:ConvexOS:*:* | convex:ConvexOS:C34*:*)
+ echo c34-convex-bsd
+ exit 0 ;;
+ C38*:ConvexOS:*:* | convex:ConvexOS:C38*:*)
+ echo c38-convex-bsd
+ exit 0 ;;
+ C4*:ConvexOS:*:* | convex:ConvexOS:C4*:*)
+ echo c4-convex-bsd
+ exit 0 ;;
+ CRAY*Y-MP:*:*:*)
+ echo ymp-cray-unicos${UNAME_RELEASE} | sed -e 's/\.[^.]*$/.X/'
+ exit 0 ;;
+ CRAY*[A-Z]90:*:*:*)
+ echo ${UNAME_MACHINE}-cray-unicos${UNAME_RELEASE} \
+ | sed -e 's/CRAY.*\([A-Z]90\)/\1/' \
+ -e y/ABCDEFGHIJKLMNOPQRSTUVWXYZ/abcdefghijklmnopqrstuvwxyz/ \
+ -e 's/\.[^.]*$/.X/'
+ exit 0 ;;
+ CRAY*TS:*:*:*)
+ echo t90-cray-unicos${UNAME_RELEASE} | sed -e 's/\.[^.]*$/.X/'
+ exit 0 ;;
+ CRAY*T3D:*:*:*)
+ echo alpha-cray-unicosmk${UNAME_RELEASE} | sed -e 's/\.[^.]*$/.X/'
+ exit 0 ;;
+ CRAY*T3E:*:*:*)
+ echo alphaev5-cray-unicosmk${UNAME_RELEASE} | sed -e 's/\.[^.]*$/.X/'
+ exit 0 ;;
+ CRAY*SV1:*:*:*)
+ echo sv1-cray-unicos${UNAME_RELEASE} | sed -e 's/\.[^.]*$/.X/'
+ exit 0 ;;
+ F30[01]:UNIX_System_V:*:* | F700:UNIX_System_V:*:*)
+ FUJITSU_PROC=`uname -m | tr 'ABCDEFGHIJKLMNOPQRSTUVWXYZ' 'abcdefghijklmnopqrstuvwxyz'`
+ FUJITSU_SYS=`uname -p | tr 'ABCDEFGHIJKLMNOPQRSTUVWXYZ' 'abcdefghijklmnopqrstuvwxyz' | sed -e 's/\///'`
+ FUJITSU_REL=`echo ${UNAME_RELEASE} | sed -e 's/ /_/'`
+ echo "${FUJITSU_PROC}-fujitsu-${FUJITSU_SYS}${FUJITSU_REL}"
+ exit 0 ;;
+ i*86:BSD/386:*:* | i*86:BSD/OS:*:* | *:Ascend\ Embedded/OS:*:*)
+ echo ${UNAME_MACHINE}-pc-bsdi${UNAME_RELEASE}
+ exit 0 ;;
+ sparc*:BSD/OS:*:*)
+ echo sparc-unknown-bsdi${UNAME_RELEASE}
+ exit 0 ;;
+ *:BSD/OS:*:*)
+ echo ${UNAME_MACHINE}-unknown-bsdi${UNAME_RELEASE}
+ exit 0 ;;
+ *:FreeBSD:*:*)
+ # Determine whether the default compiler uses glibc.
+ eval $set_cc_for_build
+ sed 's/^ //' << EOF >$dummy.c
+ #include <features.h>
+ #if __GLIBC__ >= 2
+ LIBC=gnu
+ #else
+ LIBC=
+ #endif
+EOF
+ eval `$CC_FOR_BUILD -E $dummy.c 2>/dev/null | grep ^LIBC=`
+ rm -f $dummy.c && rmdir $tmpdir
+ echo ${UNAME_MACHINE}-unknown-freebsd`echo ${UNAME_RELEASE}|sed -e 's/[-(].*//'`${LIBC:+-$LIBC}
+ exit 0 ;;
+ i*:CYGWIN*:*)
+ echo ${UNAME_MACHINE}-pc-cygwin
+ exit 0 ;;
+ i*:MINGW*:*)
+ echo ${UNAME_MACHINE}-pc-mingw32
+ exit 0 ;;
+ i*:PW*:*)
+ echo ${UNAME_MACHINE}-pc-pw32
+ exit 0 ;;
+ x86:Interix*:3*)
+ echo i386-pc-interix3
+ exit 0 ;;
+ i*:Windows_NT*:* | Pentium*:Windows_NT*:*)
+ # How do we know it's Interix rather than the generic POSIX subsystem?
+ # It also conflicts with pre-2.0 versions of AT&T UWIN. Should we
+ # UNAME_MACHINE based on the output of uname instead of i386?
+ echo i386-pc-interix
+ exit 0 ;;
+ i*:UWIN*:*)
+ echo ${UNAME_MACHINE}-pc-uwin
+ exit 0 ;;
+ p*:CYGWIN*:*)
+ echo powerpcle-unknown-cygwin
+ exit 0 ;;
+ prep*:SunOS:5.*:*)
+ echo powerpcle-unknown-solaris2`echo ${UNAME_RELEASE}|sed -e 's/[^.]*//'`
+ exit 0 ;;
+ *:GNU:*:*)
+ echo `echo ${UNAME_MACHINE}|sed -e 's,[-/].*$,,'`-unknown-gnu`echo ${UNAME_RELEASE}|sed -e 's,/.*$,,'`
+ exit 0 ;;
+ i*86:Minix:*:*)
+ echo ${UNAME_MACHINE}-pc-minix
+ exit 0 ;;
+ arm*:Linux:*:*)
+ echo ${UNAME_MACHINE}-unknown-linux-gnu
+ exit 0 ;;
+ ia64:Linux:*:*)
+ echo ${UNAME_MACHINE}-unknown-linux-gnu
+ exit 0 ;;
+ m68*:Linux:*:*)
+ echo ${UNAME_MACHINE}-unknown-linux-gnu
+ exit 0 ;;
+ mips:Linux:*:*)
+ eval $set_cc_for_build
+ sed 's/^ //' << EOF >$dummy.c
+ #undef CPU
+ #undef mips
+ #undef mipsel
+ #if defined(__MIPSEL__) || defined(__MIPSEL) || defined(_MIPSEL) || defined(MIPSEL)
+ CPU=mipsel
+ #else
+ #if defined(__MIPSEB__) || defined(__MIPSEB) || defined(_MIPSEB) || defined(MIPSEB)
+ CPU=mips
+ #else
+ CPU=
+ #endif
+ #endif
+EOF
+ eval `$CC_FOR_BUILD -E $dummy.c 2>/dev/null | grep ^CPU=`
+ rm -f $dummy.c && rmdir $tmpdir
+ test x"${CPU}" != x && echo "${CPU}-pc-linux-gnu" && exit 0
+ ;;
+ ppc:Linux:*:*)
+ echo powerpc-unknown-linux-gnu
+ exit 0 ;;
+ ppc64:Linux:*:*)
+ echo powerpc64-unknown-linux-gnu
+ exit 0 ;;
+ alpha:Linux:*:*)
+ case `sed -n '/^cpu model/s/^.*: \(.*\)/\1/p' < /proc/cpuinfo` in
+ EV5) UNAME_MACHINE=alphaev5 ;;
+ EV56) UNAME_MACHINE=alphaev56 ;;
+ PCA56) UNAME_MACHINE=alphapca56 ;;
+ PCA57) UNAME_MACHINE=alphapca56 ;;
+ EV6) UNAME_MACHINE=alphaev6 ;;
+ EV67) UNAME_MACHINE=alphaev67 ;;
+ EV68*) UNAME_MACHINE=alphaev68 ;;
+ esac
+ objdump --private-headers /bin/sh | grep ld.so.1 >/dev/null
+ if test "$?" = 0 ; then LIBC="libc1" ; else LIBC="" ; fi
+ echo ${UNAME_MACHINE}-unknown-linux-gnu${LIBC}
+ exit 0 ;;
+ parisc:Linux:*:* | hppa:Linux:*:*)
+ # Look for CPU level
+ case `grep '^cpu[^a-z]*:' /proc/cpuinfo 2>/dev/null | cut -d' ' -f2` in
+ PA7*) echo hppa1.1-unknown-linux-gnu ;;
+ PA8*) echo hppa2.0-unknown-linux-gnu ;;
+ *) echo hppa-unknown-linux-gnu ;;
+ esac
+ exit 0 ;;
+ parisc64:Linux:*:* | hppa64:Linux:*:*)
+ echo hppa64-unknown-linux-gnu
+ exit 0 ;;
+ s390:Linux:*:* | s390x:Linux:*:*)
+ echo ${UNAME_MACHINE}-ibm-linux
+ exit 0 ;;
+ sh*:Linux:*:*)
+ echo ${UNAME_MACHINE}-unknown-linux-gnu
+ exit 0 ;;
+ sparc:Linux:*:* | sparc64:Linux:*:*)
+ echo ${UNAME_MACHINE}-unknown-linux-gnu
+ exit 0 ;;
+ x86_64:Linux:*:*)
+ echo x86_64-unknown-linux-gnu
+ exit 0 ;;
+ i*86:Linux:*:*)
+ # The BFD linker knows what the default object file format is, so
+ # first see if it will tell us. cd to the root directory to prevent
+ # problems with other programs or directories called `ld' in the path.
+ # Set LC_ALL=C to ensure ld outputs messages in English.
+ ld_supported_targets=`cd /; LC_ALL=C ld --help 2>&1 \
+ | sed -ne '/supported targets:/!d
+ s/[ ][ ]*/ /g
+ s/.*supported targets: *//
+ s/ .*//
+ p'`
+ case "$ld_supported_targets" in
+ elf32-i386)
+ TENTATIVE="${UNAME_MACHINE}-pc-linux-gnu"
+ ;;
+ a.out-i386-linux)
+ echo "${UNAME_MACHINE}-pc-linux-gnuaout"
+ exit 0 ;;
+ coff-i386)
+ echo "${UNAME_MACHINE}-pc-linux-gnucoff"
+ exit 0 ;;
+ "")
+ # Either a pre-BFD a.out linker (linux-gnuoldld) or
+ # one that does not give us useful --help.
+ echo "${UNAME_MACHINE}-pc-linux-gnuoldld"
+ exit 0 ;;
+ esac
+ # Determine whether the default compiler is a.out or elf
+ eval $set_cc_for_build
+ sed 's/^ //' << EOF >$dummy.c
+ #include <features.h>
+ #ifdef __ELF__
+ # ifdef __GLIBC__
+ # if __GLIBC__ >= 2
+ LIBC=gnu
+ # else
+ LIBC=gnulibc1
+ # endif
+ # else
+ LIBC=gnulibc1
+ # endif
+ #else
+ #ifdef __INTEL_COMPILER
+ LIBC=gnu
+ #else
+ LIBC=gnuaout
+ #endif
+ #endif
+EOF
+ eval `$CC_FOR_BUILD -E $dummy.c 2>/dev/null | grep ^LIBC=`
+ rm -f $dummy.c && rmdir $tmpdir
+ test x"${LIBC}" != x && echo "${UNAME_MACHINE}-pc-linux-${LIBC}" && exit 0
+ test x"${TENTATIVE}" != x && echo "${TENTATIVE}" && exit 0
+ ;;
+ i*86:DYNIX/ptx:4*:*)
+ # ptx 4.0 does uname -s correctly, with DYNIX/ptx in there.
+ # earlier versions are messed up and put the nodename in both
+ # sysname and nodename.
+ echo i386-sequent-sysv4
+ exit 0 ;;
+ i*86:UNIX_SV:4.2MP:2.*)
+ # Unixware is an offshoot of SVR4, but it has its own version
+ # number series starting with 2...
+ # I am not positive that other SVR4 systems won't match this,
+ # I just have to hope. -- rms.
+ # Use sysv4.2uw... so that sysv4* matches it.
+ echo ${UNAME_MACHINE}-pc-sysv4.2uw${UNAME_VERSION}
+ exit 0 ;;
+ i*86:*:4.*:* | i*86:SYSTEM_V:4.*:*)
+ UNAME_REL=`echo ${UNAME_RELEASE} | sed 's/\/MP$//'`
+ if grep Novell /usr/include/link.h >/dev/null 2>/dev/null; then
+ echo ${UNAME_MACHINE}-univel-sysv${UNAME_REL}
+ else
+ echo ${UNAME_MACHINE}-pc-sysv${UNAME_REL}
+ fi
+ exit 0 ;;
+ i*86:*:5:[78]*)
+ case `/bin/uname -X | grep "^Machine"` in
+ *486*) UNAME_MACHINE=i486 ;;
+ *Pentium) UNAME_MACHINE=i586 ;;
+ *Pent*|*Celeron) UNAME_MACHINE=i686 ;;
+ esac
+ echo ${UNAME_MACHINE}-unknown-sysv${UNAME_RELEASE}${UNAME_SYSTEM}${UNAME_VERSION}
+ exit 0 ;;
+ i*86:*:3.2:*)
+ if test -f /usr/options/cb.name; then
+ UNAME_REL=`sed -n 's/.*Version //p' </usr/options/cb.name`
+ echo ${UNAME_MACHINE}-pc-isc$UNAME_REL
+ elif /bin/uname -X 2>/dev/null >/dev/null ; then
+ UNAME_REL=`(/bin/uname -X|grep Release|sed -e 's/.*= //')`
+ (/bin/uname -X|grep i80486 >/dev/null) && UNAME_MACHINE=i486
+ (/bin/uname -X|grep '^Machine.*Pentium' >/dev/null) \
+ && UNAME_MACHINE=i586
+ (/bin/uname -X|grep '^Machine.*Pent *II' >/dev/null) \
+ && UNAME_MACHINE=i686
+ (/bin/uname -X|grep '^Machine.*Pentium Pro' >/dev/null) \
+ && UNAME_MACHINE=i686
+ echo ${UNAME_MACHINE}-pc-sco$UNAME_REL
+ else
+ echo ${UNAME_MACHINE}-pc-sysv32
+ fi
+ exit 0 ;;
+ i*86:*DOS:*:*)
+ echo ${UNAME_MACHINE}-pc-msdosdjgpp
+ exit 0 ;;
+ pc:*:*:*)
+ # Left here for compatibility:
+ # uname -m prints for DJGPP always 'pc', but it prints nothing about
+ # the processor, so we play safe by assuming i386.
+ echo i386-pc-msdosdjgpp
+ exit 0 ;;
+ Intel:Mach:3*:*)
+ echo i386-pc-mach3
+ exit 0 ;;
+ paragon:*:*:*)
+ echo i860-intel-osf1
+ exit 0 ;;
+ i860:*:4.*:*) # i860-SVR4
+ if grep Stardent /usr/include/sys/uadmin.h >/dev/null 2>&1 ; then
+ echo i860-stardent-sysv${UNAME_RELEASE} # Stardent Vistra i860-SVR4
+ else # Add other i860-SVR4 vendors below as they are discovered.
+ echo i860-unknown-sysv${UNAME_RELEASE} # Unknown i860-SVR4
+ fi
+ exit 0 ;;
+ mini*:CTIX:SYS*5:*)
+ # "miniframe"
+ echo m68010-convergent-sysv
+ exit 0 ;;
+ M68*:*:R3V[567]*:*)
+ test -r /sysV68 && echo 'm68k-motorola-sysv' && exit 0 ;;
+ 3[34]??:*:4.0:3.0 | 3[34]??A:*:4.0:3.0 | 3[34]??,*:*:4.0:3.0 | 3[34]??/*:*:4.0:3.0 | 4400:*:4.0:3.0 | 4850:*:4.0:3.0 | SKA40:*:4.0:3.0)
+ OS_REL=''
+ test -r /etc/.relid \
+ && OS_REL=.`sed -n 's/[^ ]* [^ ]* \([0-9][0-9]\).*/\1/p' < /etc/.relid`
+ /bin/uname -p 2>/dev/null | grep 86 >/dev/null \
+ && echo i486-ncr-sysv4.3${OS_REL} && exit 0
+ /bin/uname -p 2>/dev/null | /bin/grep entium >/dev/null \
+ && echo i586-ncr-sysv4.3${OS_REL} && exit 0 ;;
+ 3[34]??:*:4.0:* | 3[34]??,*:*:4.0:*)
+ /bin/uname -p 2>/dev/null | grep 86 >/dev/null \
+ && echo i486-ncr-sysv4 && exit 0 ;;
+ m68*:LynxOS:2.*:* | m68*:LynxOS:3.0*:*)
+ echo m68k-unknown-lynxos${UNAME_RELEASE}
+ exit 0 ;;
+ mc68030:UNIX_System_V:4.*:*)
+ echo m68k-atari-sysv4
+ exit 0 ;;
+ i*86:LynxOS:2.*:* | i*86:LynxOS:3.[01]*:* | i*86:LynxOS:4.0*:*)
+ echo i386-unknown-lynxos${UNAME_RELEASE}
+ exit 0 ;;
+ TSUNAMI:LynxOS:2.*:*)
+ echo sparc-unknown-lynxos${UNAME_RELEASE}
+ exit 0 ;;
+ rs6000:LynxOS:2.*:*)
+ echo rs6000-unknown-lynxos${UNAME_RELEASE}
+ exit 0 ;;
+ PowerPC:LynxOS:2.*:* | PowerPC:LynxOS:3.[01]*:* | PowerPC:LynxOS:4.0*:*)
+ echo powerpc-unknown-lynxos${UNAME_RELEASE}
+ exit 0 ;;
+ SM[BE]S:UNIX_SV:*:*)
+ echo mips-dde-sysv${UNAME_RELEASE}
+ exit 0 ;;
+ RM*:ReliantUNIX-*:*:*)
+ echo mips-sni-sysv4
+ exit 0 ;;
+ RM*:SINIX-*:*:*)
+ echo mips-sni-sysv4
+ exit 0 ;;
+ *:SINIX-*:*:*)
+ if uname -p 2>/dev/null >/dev/null ; then
+ UNAME_MACHINE=`(uname -p) 2>/dev/null`
+ echo ${UNAME_MACHINE}-sni-sysv4
+ else
+ echo ns32k-sni-sysv
+ fi
+ exit 0 ;;
+ PENTIUM:*:4.0*:*) # Unisys `ClearPath HMP IX 4000' SVR4/MP effort
+ # says <Richard.M.Bartel at ccMail.Census.GOV>
+ echo i586-unisys-sysv4
+ exit 0 ;;
+ *:UNIX_System_V:4*:FTX*)
+ # From Gerald Hewes <hewes at openmarket.com>.
+ # How about differentiating between stratus architectures? -djm
+ echo hppa1.1-stratus-sysv4
+ exit 0 ;;
+ *:*:*:FTX*)
+ # From seanf at swdc.stratus.com.
+ echo i860-stratus-sysv4
+ exit 0 ;;
+ *:VOS:*:*)
+ # From Paul.Green at stratus.com.
+ echo hppa1.1-stratus-vos
+ exit 0 ;;
+ mc68*:A/UX:*:*)
+ echo m68k-apple-aux${UNAME_RELEASE}
+ exit 0 ;;
+ news*:NEWS-OS:6*:*)
+ echo mips-sony-newsos6
+ exit 0 ;;
+ R[34]000:*System_V*:*:* | R4000:UNIX_SYSV:*:* | R*000:UNIX_SV:*:*)
+ if [ -d /usr/nec ]; then
+ echo mips-nec-sysv${UNAME_RELEASE}
+ else
+ echo mips-unknown-sysv${UNAME_RELEASE}
+ fi
+ exit 0 ;;
+ BeBox:BeOS:*:*) # BeOS running on hardware made by Be, PPC only.
+ echo powerpc-be-beos
+ exit 0 ;;
+ BeMac:BeOS:*:*) # BeOS running on Mac or Mac clone, PPC only.
+ echo powerpc-apple-beos
+ exit 0 ;;
+ BePC:BeOS:*:*) # BeOS running on Intel PC compatible.
+ echo i586-pc-beos
+ exit 0 ;;
+ SX-4:SUPER-UX:*:*)
+ echo sx4-nec-superux${UNAME_RELEASE}
+ exit 0 ;;
+ SX-5:SUPER-UX:*:*)
+ echo sx5-nec-superux${UNAME_RELEASE}
+ exit 0 ;;
+ Power*:Rhapsody:*:*)
+ echo powerpc-apple-rhapsody${UNAME_RELEASE}
+ exit 0 ;;
+ *:Rhapsody:*:*)
+ echo ${UNAME_MACHINE}-apple-rhapsody${UNAME_RELEASE}
+ exit 0 ;;
+ *:Darwin:*:*)
+ echo `uname -p`-apple-darwin${UNAME_RELEASE}
+ exit 0 ;;
+ *:procnto*:*:* | *:QNX:[0123456789]*:*)
+ UNAME_PROCESSOR=`uname -p`
+ if test "$UNAME_PROCESSOR" = "x86"; then
+ UNAME_PROCESSOR=i386
+ UNAME_MACHINE=pc
+ fi
+ echo ${UNAME_PROCESSOR}-${UNAME_MACHINE}-nto-qnx${UNAME_RELEASE}
+ exit 0 ;;
+ *:QNX:*:4*)
+ echo i386-pc-qnx
+ exit 0 ;;
+ NSR-[GKLNPTVW]:NONSTOP_KERNEL:*:*)
+ echo nsr-tandem-nsk${UNAME_RELEASE}
+ exit 0 ;;
+ *:NonStop-UX:*:*)
+ echo mips-compaq-nonstopux
+ exit 0 ;;
+ BS2000:POSIX*:*:*)
+ echo bs2000-siemens-sysv
+ exit 0 ;;
+ DS/*:UNIX_System_V:*:*)
+ echo ${UNAME_MACHINE}-${UNAME_SYSTEM}-${UNAME_RELEASE}
+ exit 0 ;;
+ *:Plan9:*:*)
+ # "uname -m" is not consistent, so use $cputype instead. 386
+ # is converted to i386 for consistency with other x86
+ # operating systems.
+ if test "$cputype" = "386"; then
+ UNAME_MACHINE=i386
+ else
+ UNAME_MACHINE="$cputype"
+ fi
+ echo ${UNAME_MACHINE}-unknown-plan9
+ exit 0 ;;
+ i*86:OS/2:*:*)
+ # If we were able to find `uname', then EMX Unix compatibility
+ # is probably installed.
+ echo ${UNAME_MACHINE}-pc-os2-emx
+ exit 0 ;;
+ *:TOPS-10:*:*)
+ echo pdp10-unknown-tops10
+ exit 0 ;;
+ *:TENEX:*:*)
+ echo pdp10-unknown-tenex
+ exit 0 ;;
+ KS10:TOPS-20:*:* | KL10:TOPS-20:*:* | TYPE4:TOPS-20:*:*)
+ echo pdp10-dec-tops20
+ exit 0 ;;
+ XKL-1:TOPS-20:*:* | TYPE5:TOPS-20:*:*)
+ echo pdp10-xkl-tops20
+ exit 0 ;;
+ *:TOPS-20:*:*)
+ echo pdp10-unknown-tops20
+ exit 0 ;;
+ *:ITS:*:*)
+ echo pdp10-unknown-its
+ exit 0 ;;
+ i*86:XTS-300:*:STOP)
+ echo ${UNAME_MACHINE}-unknown-stop
+ exit 0 ;;
+ i*86:atheos:*:*)
+ echo ${UNAME_MACHINE}-unknown-atheos
+ exit 0 ;;
+esac
+
+#echo '(No uname command or uname output not recognized.)' 1>&2
+#echo "${UNAME_MACHINE}:${UNAME_SYSTEM}:${UNAME_RELEASE}:${UNAME_VERSION}" 1>&2
+
+eval $set_cc_for_build
+cat >$dummy.c <<EOF
+#ifdef _SEQUENT_
+# include <sys/types.h>
+# include <sys/utsname.h>
+#endif
+main ()
+{
+#if defined (sony)
+#if defined (MIPSEB)
+ /* BFD wants "bsd" instead of "newsos". Perhaps BFD should be changed,
+ I don't know.... */
+ printf ("mips-sony-bsd\n"); exit (0);
+#else
+#include <sys/param.h>
+ printf ("m68k-sony-newsos%s\n",
+#ifdef NEWSOS4
+ "4"
+#else
+ ""
+#endif
+ ); exit (0);
+#endif
+#endif
+
+#if defined (__arm) && defined (__acorn) && defined (__unix)
+ printf ("arm-acorn-riscix"); exit (0);
+#endif
+
+#if defined (hp300) && !defined (hpux)
+ printf ("m68k-hp-bsd\n"); exit (0);
+#endif
+
+#if defined (NeXT)
+#if !defined (__ARCHITECTURE__)
+#define __ARCHITECTURE__ "m68k"
+#endif
+ int version;
+ version=`(hostinfo | sed -n 's/.*NeXT Mach \([0-9]*\).*/\1/p') 2>/dev/null`;
+ if (version < 4)
+ printf ("%s-next-nextstep%d\n", __ARCHITECTURE__, version);
+ else
+ printf ("%s-next-openstep%d\n", __ARCHITECTURE__, version);
+ exit (0);
+#endif
+
+#if defined (MULTIMAX) || defined (n16)
+#if defined (UMAXV)
+ printf ("ns32k-encore-sysv\n"); exit (0);
+#else
+#if defined (CMU)
+ printf ("ns32k-encore-mach\n"); exit (0);
+#else
+ printf ("ns32k-encore-bsd\n"); exit (0);
+#endif
+#endif
+#endif
+
+#if defined (__386BSD__)
+ printf ("i386-pc-bsd\n"); exit (0);
+#endif
+
+#if defined (sequent)
+#if defined (i386)
+ printf ("i386-sequent-dynix\n"); exit (0);
+#endif
+#if defined (ns32000)
+ printf ("ns32k-sequent-dynix\n"); exit (0);
+#endif
+#endif
+
+#if defined (_SEQUENT_)
+ struct utsname un;
+
+ uname(&un);
+
+ if (strncmp(un.version, "V2", 2) == 0) {
+ printf ("i386-sequent-ptx2\n"); exit (0);
+ }
+ if (strncmp(un.version, "V1", 2) == 0) { /* XXX is V1 correct? */
+ printf ("i386-sequent-ptx1\n"); exit (0);
+ }
+ printf ("i386-sequent-ptx\n"); exit (0);
+
+#endif
+
+#if defined (vax)
+# if !defined (ultrix)
+# include <sys/param.h>
+# if defined (BSD)
+# if BSD == 43
+ printf ("vax-dec-bsd4.3\n"); exit (0);
+# else
+# if BSD == 199006
+ printf ("vax-dec-bsd4.3reno\n"); exit (0);
+# else
+ printf ("vax-dec-bsd\n"); exit (0);
+# endif
+# endif
+# else
+ printf ("vax-dec-bsd\n"); exit (0);
+# endif
+# else
+ printf ("vax-dec-ultrix\n"); exit (0);
+# endif
+#endif
+
+#if defined (alliant) && defined (i860)
+ printf ("i860-alliant-bsd\n"); exit (0);
+#endif
+
+ exit (1);
+}
+EOF
+
+$CC_FOR_BUILD $dummy.c -o $dummy 2>/dev/null && $dummy && rm -f $dummy.c $dummy && rmdir $tmpdir && exit 0
+rm -f $dummy.c $dummy && rmdir $tmpdir
+
+# Apollos put the system type in the environment.
+
+test -d /usr/apollo && { echo ${ISP}-apollo-${SYSTYPE}; exit 0; }
+
+# Convex versions that predate uname can use getsysinfo(1)
+
+if [ -x /usr/convex/getsysinfo ]
+then
+ case `getsysinfo -f cpu_type` in
+ c1*)
+ echo c1-convex-bsd
+ exit 0 ;;
+ c2*)
+ if getsysinfo -f scalar_acc
+ then echo c32-convex-bsd
+ else echo c2-convex-bsd
+ fi
+ exit 0 ;;
+ c34*)
+ echo c34-convex-bsd
+ exit 0 ;;
+ c38*)
+ echo c38-convex-bsd
+ exit 0 ;;
+ c4*)
+ echo c4-convex-bsd
+ exit 0 ;;
+ esac
+fi
+
+cat >&2 <<EOF
+$0: unable to guess system type
+
+This script, last modified $timestamp, has failed to recognize
+the operating system you are using. It is advised that you
+download the most up to date version of the config scripts from
+
+ ftp://ftp.gnu.org/pub/gnu/config/
+
+If the version you run ($0) is already up to date, please
+send the following data and any information you think might be
+pertinent to <config-patches at gnu.org> in order to provide the needed
+information to handle your system.
+
+config.guess timestamp = $timestamp
+
+uname -m = `(uname -m) 2>/dev/null || echo unknown`
+uname -r = `(uname -r) 2>/dev/null || echo unknown`
+uname -s = `(uname -s) 2>/dev/null || echo unknown`
+uname -v = `(uname -v) 2>/dev/null || echo unknown`
+
+/usr/bin/uname -p = `(/usr/bin/uname -p) 2>/dev/null`
+/bin/uname -X = `(/bin/uname -X) 2>/dev/null`
+
+hostinfo = `(hostinfo) 2>/dev/null`
+/bin/universe = `(/bin/universe) 2>/dev/null`
+/usr/bin/arch -k = `(/usr/bin/arch -k) 2>/dev/null`
+/bin/arch = `(/bin/arch) 2>/dev/null`
+/usr/bin/oslevel = `(/usr/bin/oslevel) 2>/dev/null`
+/usr/convex/getsysinfo = `(/usr/convex/getsysinfo) 2>/dev/null`
+
+UNAME_MACHINE = ${UNAME_MACHINE}
+UNAME_RELEASE = ${UNAME_RELEASE}
+UNAME_SYSTEM = ${UNAME_SYSTEM}
+UNAME_VERSION = ${UNAME_VERSION}
+EOF
+
+exit 1
+
+# Local variables:
+# eval: (add-hook 'write-file-hooks 'time-stamp)
+# time-stamp-start: "timestamp='"
+# time-stamp-format: "%:y-%02m-%02d"
+# time-stamp-end: "'"
+# End:
Property changes on: trunk/packages/rnahybrid/branches/upstream/current/config.guess
___________________________________________________________________
Name: svn:executable
+
Added: trunk/packages/rnahybrid/branches/upstream/current/config.h.in
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/config.h.in (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/config.h.in 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,71 @@
+/* config.h.in. Generated from configure.in by autoheader. */
+
+/* Define to 1 if you have the <inttypes.h> header file. */
+#undef HAVE_INTTYPES_H
+
+/* Define to 1 if you have the `g2' library (-lg2). */
+#undef HAVE_LIBG2
+
+/* Define to 1 if you have the `gd' library (-lgd). */
+#undef HAVE_LIBGD
+
+/* Define to 1 if you have the `m' library (-lm). */
+#undef HAVE_LIBM
+
+/* Define to 1 if you have the <memory.h> header file. */
+#undef HAVE_MEMORY_H
+
+/* Define to 1 if you have the <stdint.h> header file. */
+#undef HAVE_STDINT_H
+
+/* Define to 1 if you have the <stdlib.h> header file. */
+#undef HAVE_STDLIB_H
+
+/* Define to 1 if you have the <strings.h> header file. */
+#undef HAVE_STRINGS_H
+
+/* Define to 1 if you have the <string.h> header file. */
+#undef HAVE_STRING_H
+
+/* Define to 1 if you have the <sys/stat.h> header file. */
+#undef HAVE_SYS_STAT_H
+
+/* Define to 1 if you have the <sys/types.h> header file. */
+#undef HAVE_SYS_TYPES_H
+
+/* Define to 1 if you have the <unistd.h> header file. */
+#undef HAVE_UNISTD_H
+
+/* Name of package */
+#undef PACKAGE
+
+/* Define to the address where bug reports for this package should be sent. */
+#undef PACKAGE_BUGREPORT
+
+/* Define to the full name of this package. */
+#undef PACKAGE_NAME
+
+/* Define to the full name and version of this package. */
+#undef PACKAGE_STRING
+
+/* Define to the one symbol short name of this package. */
+#undef PACKAGE_TARNAME
+
+/* Define to the version of this package. */
+#undef PACKAGE_VERSION
+
+/* Define to 1 if you have the ANSI C header files. */
+#undef STDC_HEADERS
+
+/* Version number of package */
+#undef VERSION
+
+/* Define to empty if `const' does not conform to ANSI C. */
+#undef const
+
+/* Define as `__inline' if that's what the C compiler calls it, or to nothing
+ if it is not supported. */
+#undef inline
+
+/* Define to `unsigned' if <sys/types.h> does not define. */
+#undef size_t
Added: trunk/packages/rnahybrid/branches/upstream/current/configure
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/configure (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/configure 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,5171 @@
+#! /bin/sh
+# From configure.in Revision: 1.0 .
+# Guess values for system-dependent variables and create Makefiles.
+# Generated by GNU Autoconf 2.57 for RNAhybrid 1.0.
+#
+# Report bugs to <marc at techfak.uni-bielefeld.de>.
+#
+# Copyright 1992, 1993, 1994, 1995, 1996, 1998, 1999, 2000, 2001, 2002
+# Free Software Foundation, Inc.
+# This configure script is free software; the Free Software Foundation
+# gives unlimited permission to copy, distribute and modify it.
+## --------------------- ##
+## M4sh Initialization. ##
+## --------------------- ##
+
+# Be Bourne compatible
+if test -n "${ZSH_VERSION+set}" && (emulate sh) >/dev/null 2>&1; then
+ emulate sh
+ NULLCMD=:
+ # Zsh 3.x and 4.x performs word splitting on ${1+"$@"}, which
+ # is contrary to our usage. Disable this feature.
+ alias -g '${1+"$@"}'='"$@"'
+elif test -n "${BASH_VERSION+set}" && (set -o posix) >/dev/null 2>&1; then
+ set -o posix
+fi
+
+# Support unset when possible.
+if (FOO=FOO; unset FOO) >/dev/null 2>&1; then
+ as_unset=unset
+else
+ as_unset=false
+fi
+
+
+# Work around bugs in pre-3.0 UWIN ksh.
+$as_unset ENV MAIL MAILPATH
+PS1='$ '
+PS2='> '
+PS4='+ '
+
+# NLS nuisances.
+for as_var in \
+ LANG LANGUAGE LC_ADDRESS LC_ALL LC_COLLATE LC_CTYPE LC_IDENTIFICATION \
+ LC_MEASUREMENT LC_MESSAGES LC_MONETARY LC_NAME LC_NUMERIC LC_PAPER \
+ LC_TELEPHONE LC_TIME
+do
+ if (set +x; test -n "`(eval $as_var=C; export $as_var) 2>&1`"); then
+ eval $as_var=C; export $as_var
+ else
+ $as_unset $as_var
+ fi
+done
+
+# Required to use basename.
+if expr a : '\(a\)' >/dev/null 2>&1; then
+ as_expr=expr
+else
+ as_expr=false
+fi
+
+if (basename /) >/dev/null 2>&1 && test "X`basename / 2>&1`" = "X/"; then
+ as_basename=basename
+else
+ as_basename=false
+fi
+
+
+# Name of the executable.
+as_me=`$as_basename "$0" ||
+$as_expr X/"$0" : '.*/\([^/][^/]*\)/*$' \| \
+ X"$0" : 'X\(//\)$' \| \
+ X"$0" : 'X\(/\)$' \| \
+ . : '\(.\)' 2>/dev/null ||
+echo X/"$0" |
+ sed '/^.*\/\([^/][^/]*\)\/*$/{ s//\1/; q; }
+ /^X\/\(\/\/\)$/{ s//\1/; q; }
+ /^X\/\(\/\).*/{ s//\1/; q; }
+ s/.*/./; q'`
+
+
+# PATH needs CR, and LINENO needs CR and PATH.
+# Avoid depending upon Character Ranges.
+as_cr_letters='abcdefghijklmnopqrstuvwxyz'
+as_cr_LETTERS='ABCDEFGHIJKLMNOPQRSTUVWXYZ'
+as_cr_Letters=$as_cr_letters$as_cr_LETTERS
+as_cr_digits='0123456789'
+as_cr_alnum=$as_cr_Letters$as_cr_digits
+
+# The user is always right.
+if test "${PATH_SEPARATOR+set}" != set; then
+ echo "#! /bin/sh" >conf$$.sh
+ echo "exit 0" >>conf$$.sh
+ chmod +x conf$$.sh
+ if (PATH="/nonexistent;."; conf$$.sh) >/dev/null 2>&1; then
+ PATH_SEPARATOR=';'
+ else
+ PATH_SEPARATOR=:
+ fi
+ rm -f conf$$.sh
+fi
+
+
+ as_lineno_1=$LINENO
+ as_lineno_2=$LINENO
+ as_lineno_3=`(expr $as_lineno_1 + 1) 2>/dev/null`
+ test "x$as_lineno_1" != "x$as_lineno_2" &&
+ test "x$as_lineno_3" = "x$as_lineno_2" || {
+ # Find who we are. Look in the path if we contain no path at all
+ # relative or not.
+ case $0 in
+ *[\\/]* ) as_myself=$0 ;;
+ *) as_save_IFS=$IFS; IFS=$PATH_SEPARATOR
+for as_dir in $PATH
+do
+ IFS=$as_save_IFS
+ test -z "$as_dir" && as_dir=.
+ test -r "$as_dir/$0" && as_myself=$as_dir/$0 && break
+done
+
+ ;;
+ esac
+ # We did not find ourselves, most probably we were run as `sh COMMAND'
+ # in which case we are not to be found in the path.
+ if test "x$as_myself" = x; then
+ as_myself=$0
+ fi
+ if test ! -f "$as_myself"; then
+ { echo "$as_me: error: cannot find myself; rerun with an absolute path" >&2
+ { (exit 1); exit 1; }; }
+ fi
+ case $CONFIG_SHELL in
+ '')
+ as_save_IFS=$IFS; IFS=$PATH_SEPARATOR
+for as_dir in /bin$PATH_SEPARATOR/usr/bin$PATH_SEPARATOR$PATH
+do
+ IFS=$as_save_IFS
+ test -z "$as_dir" && as_dir=.
+ for as_base in sh bash ksh sh5; do
+ case $as_dir in
+ /*)
+ if ("$as_dir/$as_base" -c '
+ as_lineno_1=$LINENO
+ as_lineno_2=$LINENO
+ as_lineno_3=`(expr $as_lineno_1 + 1) 2>/dev/null`
+ test "x$as_lineno_1" != "x$as_lineno_2" &&
+ test "x$as_lineno_3" = "x$as_lineno_2" ') 2>/dev/null; then
+ $as_unset BASH_ENV || test "${BASH_ENV+set}" != set || { BASH_ENV=; export BASH_ENV; }
+ $as_unset ENV || test "${ENV+set}" != set || { ENV=; export ENV; }
+ CONFIG_SHELL=$as_dir/$as_base
+ export CONFIG_SHELL
+ exec "$CONFIG_SHELL" "$0" ${1+"$@"}
+ fi;;
+ esac
+ done
+done
+;;
+ esac
+
+ # Create $as_me.lineno as a copy of $as_myself, but with $LINENO
+ # uniformly replaced by the line number. The first 'sed' inserts a
+ # line-number line before each line; the second 'sed' does the real
+ # work. The second script uses 'N' to pair each line-number line
+ # with the numbered line, and appends trailing '-' during
+ # substitution so that $LINENO is not a special case at line end.
+ # (Raja R Harinath suggested sed '=', and Paul Eggert wrote the
+ # second 'sed' script. Blame Lee E. McMahon for sed's syntax. :-)
+ sed '=' <$as_myself |
+ sed '
+ N
+ s,$,-,
+ : loop
+ s,^\(['$as_cr_digits']*\)\(.*\)[$]LINENO\([^'$as_cr_alnum'_]\),\1\2\1\3,
+ t loop
+ s,-$,,
+ s,^['$as_cr_digits']*\n,,
+ ' >$as_me.lineno &&
+ chmod +x $as_me.lineno ||
+ { echo "$as_me: error: cannot create $as_me.lineno; rerun with a POSIX shell" >&2
+ { (exit 1); exit 1; }; }
+
+ # Don't try to exec as it changes $[0], causing all sort of problems
+ # (the dirname of $[0] is not the place where we might find the
+ # original and so on. Autoconf is especially sensible to this).
+ . ./$as_me.lineno
+ # Exit status is that of the last command.
+ exit
+}
+
+
+case `echo "testing\c"; echo 1,2,3`,`echo -n testing; echo 1,2,3` in
+ *c*,-n*) ECHO_N= ECHO_C='
+' ECHO_T=' ' ;;
+ *c*,* ) ECHO_N=-n ECHO_C= ECHO_T= ;;
+ *) ECHO_N= ECHO_C='\c' ECHO_T= ;;
+esac
+
+if expr a : '\(a\)' >/dev/null 2>&1; then
+ as_expr=expr
+else
+ as_expr=false
+fi
+
+rm -f conf$$ conf$$.exe conf$$.file
+echo >conf$$.file
+if ln -s conf$$.file conf$$ 2>/dev/null; then
+ # We could just check for DJGPP; but this test a) works b) is more generic
+ # and c) will remain valid once DJGPP supports symlinks (DJGPP 2.04).
+ if test -f conf$$.exe; then
+ # Don't use ln at all; we don't have any links
+ as_ln_s='cp -p'
+ else
+ as_ln_s='ln -s'
+ fi
+elif ln conf$$.file conf$$ 2>/dev/null; then
+ as_ln_s=ln
+else
+ as_ln_s='cp -p'
+fi
+rm -f conf$$ conf$$.exe conf$$.file
+
+if mkdir -p . 2>/dev/null; then
+ as_mkdir_p=:
+else
+ as_mkdir_p=false
+fi
+
+as_executable_p="test -f"
+
+# Sed expression to map a string onto a valid CPP name.
+as_tr_cpp="sed y%*$as_cr_letters%P$as_cr_LETTERS%;s%[^_$as_cr_alnum]%_%g"
+
+# Sed expression to map a string onto a valid variable name.
+as_tr_sh="sed y%*+%pp%;s%[^_$as_cr_alnum]%_%g"
+
+
+# IFS
+# We need space, tab and new line, in precisely that order.
+as_nl='
+'
+IFS=" $as_nl"
+
+# CDPATH.
+$as_unset CDPATH
+
+
+# Name of the host.
+# hostname on some systems (SVR3.2, Linux) returns a bogus exit status,
+# so uname gets run too.
+ac_hostname=`(hostname || uname -n) 2>/dev/null | sed 1q`
+
+exec 6>&1
+
+#
+# Initializations.
+#
+ac_default_prefix=/usr/local
+ac_config_libobj_dir=.
+cross_compiling=no
+subdirs=
+MFLAGS=
+MAKEFLAGS=
+SHELL=${CONFIG_SHELL-/bin/sh}
+
+# Maximum number of lines to put in a shell here document.
+# This variable seems obsolete. It should probably be removed, and
+# only ac_max_sed_lines should be used.
+: ${ac_max_here_lines=38}
+
+# Identity of this package.
+PACKAGE_NAME='RNAhybrid'
+PACKAGE_TARNAME='RNAhybrid'
+PACKAGE_VERSION='1.0'
+PACKAGE_STRING='RNAhybrid 1.0'
+PACKAGE_BUGREPORT='marc at techfak.uni-bielefeld.de'
+
+# Factoring default headers for most tests.
+ac_includes_default="\
+#include <stdio.h>
+#if HAVE_SYS_TYPES_H
+# include <sys/types.h>
+#endif
+#if HAVE_SYS_STAT_H
+# include <sys/stat.h>
+#endif
+#if STDC_HEADERS
+# include <stdlib.h>
+# include <stddef.h>
+#else
+# if HAVE_STDLIB_H
+# include <stdlib.h>
+# endif
+#endif
+#if HAVE_STRING_H
+# if !STDC_HEADERS && HAVE_MEMORY_H
+# include <memory.h>
+# endif
+# include <string.h>
+#endif
+#if HAVE_STRINGS_H
+# include <strings.h>
+#endif
+#if HAVE_INTTYPES_H
+# include <inttypes.h>
+#else
+# if HAVE_STDINT_H
+# include <stdint.h>
+# endif
+#endif
+#if HAVE_UNISTD_H
+# include <unistd.h>
+#endif"
+
+ac_subst_vars='SHELL PATH_SEPARATOR PACKAGE_NAME PACKAGE_TARNAME PACKAGE_VERSION PACKAGE_STRING PACKAGE_BUGREPORT exec_prefix prefix program_transform_name bindir sbindir libexecdir datadir sysconfdir sharedstatedir localstatedir libdir includedir oldincludedir infodir mandir build_alias host_alias target_alias DEFS ECHO_C ECHO_N ECHO_T LIBS INSTALL_PROGRAM INSTALL_SCRIPT INSTALL_DATA CYGPATH_W PACKAGE VERSION ACLOCAL AUTOCONF AUTOMAKE AUTOHEADER MAKEINFO AMTAR install_sh STRIP ac_ct_STRIP INSTALL_STRIP_PROGRAM AWK SET_MAKE am__leading_dot CC CFLAGS LDFLAGS CPPFLAGS ac_ct_CC EXEEXT OBJEXT DEPDIR am__include am__quote AMDEP_TRUE AMDEP_FALSE AMDEPBACKSLASH CCDEPMODE am__fastdepCC_TRUE am__fastdepCC_FALSE CPP EGREP LIBOBJS LTLIBOBJS'
+ac_subst_files=''
+
+# Initialize some variables set by options.
+ac_init_help=
+ac_init_version=false
+# The variables have the same names as the options, with
+# dashes changed to underlines.
+cache_file=/dev/null
+exec_prefix=NONE
+no_create=
+no_recursion=
+prefix=NONE
+program_prefix=NONE
+program_suffix=NONE
+program_transform_name=s,x,x,
+silent=
+site=
+srcdir=
+verbose=
+x_includes=NONE
+x_libraries=NONE
+
+# Installation directory options.
+# These are left unexpanded so users can "make install exec_prefix=/foo"
+# and all the variables that are supposed to be based on exec_prefix
+# by default will actually change.
+# Use braces instead of parens because sh, perl, etc. also accept them.
+bindir='${exec_prefix}/bin'
+sbindir='${exec_prefix}/sbin'
+libexecdir='${exec_prefix}/libexec'
+datadir='${prefix}/share'
+sysconfdir='${prefix}/etc'
+sharedstatedir='${prefix}/com'
+localstatedir='${prefix}/var'
+libdir='${exec_prefix}/lib'
+includedir='${prefix}/include'
+oldincludedir='/usr/include'
+infodir='${prefix}/info'
+mandir='${prefix}/man'
+
+ac_prev=
+for ac_option
+do
+ # If the previous option needs an argument, assign it.
+ if test -n "$ac_prev"; then
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+ ac_prev=
+ continue
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+
+ ac_optarg=`expr "x$ac_option" : 'x[^=]*=\(.*\)'`
+
+ # Accept the important Cygnus configure options, so we can diagnose typos.
+
+ case $ac_option in
+
+ -bindir | --bindir | --bindi | --bind | --bin | --bi)
+ ac_prev=bindir ;;
+ -bindir=* | --bindir=* | --bindi=* | --bind=* | --bin=* | --bi=*)
+ bindir=$ac_optarg ;;
+
+ -build | --build | --buil | --bui | --bu)
+ ac_prev=build_alias ;;
+ -build=* | --build=* | --buil=* | --bui=* | --bu=*)
+ build_alias=$ac_optarg ;;
+
+ -cache-file | --cache-file | --cache-fil | --cache-fi \
+ | --cache-f | --cache- | --cache | --cach | --cac | --ca | --c)
+ ac_prev=cache_file ;;
+ -cache-file=* | --cache-file=* | --cache-fil=* | --cache-fi=* \
+ | --cache-f=* | --cache-=* | --cache=* | --cach=* | --cac=* | --ca=* | --c=*)
+ cache_file=$ac_optarg ;;
+
+ --config-cache | -C)
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+
+ -datadir | --datadir | --datadi | --datad | --data | --dat | --da)
+ ac_prev=datadir ;;
+ -datadir=* | --datadir=* | --datadi=* | --datad=* | --data=* | --dat=* \
+ | --da=*)
+ datadir=$ac_optarg ;;
+
+ -disable-* | --disable-*)
+ ac_feature=`expr "x$ac_option" : 'x-*disable-\(.*\)'`
+ # Reject names that are not valid shell variable names.
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+ { (exit 1); exit 1; }; }
+ ac_feature=`echo $ac_feature | sed 's/-/_/g'`
+ eval "enable_$ac_feature=no" ;;
+
+ -enable-* | --enable-*)
+ ac_feature=`expr "x$ac_option" : 'x-*enable-\([^=]*\)'`
+ # Reject names that are not valid shell variable names.
+ expr "x$ac_feature" : ".*[^-_$as_cr_alnum]" >/dev/null &&
+ { echo "$as_me: error: invalid feature name: $ac_feature" >&2
+ { (exit 1); exit 1; }; }
+ ac_feature=`echo $ac_feature | sed 's/-/_/g'`
+ case $ac_option in
+ *=*) ac_optarg=`echo "$ac_optarg" | sed "s/'/'\\\\\\\\''/g"`;;
+ *) ac_optarg=yes ;;
+ esac
+ eval "enable_$ac_feature='$ac_optarg'" ;;
+
+ -exec-prefix | --exec_prefix | --exec-prefix | --exec-prefi \
+ | --exec-pref | --exec-pre | --exec-pr | --exec-p | --exec- \
+ | --exec | --exe | --ex)
+ ac_prev=exec_prefix ;;
+ -exec-prefix=* | --exec_prefix=* | --exec-prefix=* | --exec-prefi=* \
+ | --exec-pref=* | --exec-pre=* | --exec-pr=* | --exec-p=* | --exec-=* \
+ | --exec=* | --exe=* | --ex=*)
+ exec_prefix=$ac_optarg ;;
+
+ -gas | --gas | --ga | --g)
+ # Obsolete; use --with-gas.
+ with_gas=yes ;;
+
+ -help | --help | --hel | --he | -h)
+ ac_init_help=long ;;
+ -help=r* | --help=r* | --hel=r* | --he=r* | -hr*)
+ ac_init_help=recursive ;;
+ -help=s* | --help=s* | --hel=s* | --he=s* | -hs*)
+ ac_init_help=short ;;
+
+ -host | --host | --hos | --ho)
+ ac_prev=host_alias ;;
+ -host=* | --host=* | --hos=* | --ho=*)
+ host_alias=$ac_optarg ;;
+
+ -includedir | --includedir | --includedi | --included | --include \
+ | --includ | --inclu | --incl | --inc)
+ ac_prev=includedir ;;
+ -includedir=* | --includedir=* | --includedi=* | --included=* | --include=* \
+ | --includ=* | --inclu=* | --incl=* | --inc=*)
+ includedir=$ac_optarg ;;
+
+ -infodir | --infodir | --infodi | --infod | --info | --inf)
+ ac_prev=infodir ;;
+ -infodir=* | --infodir=* | --infodi=* | --infod=* | --info=* | --inf=*)
+ infodir=$ac_optarg ;;
+
+ -libdir | --libdir | --libdi | --libd)
+ ac_prev=libdir ;;
+ -libdir=* | --libdir=* | --libdi=* | --libd=*)
+ libdir=$ac_optarg ;;
+
+ -libexecdir | --libexecdir | --libexecdi | --libexecd | --libexec \
+ | --libexe | --libex | --libe)
+ ac_prev=libexecdir ;;
+ -libexecdir=* | --libexecdir=* | --libexecdi=* | --libexecd=* | --libexec=* \
+ | --libexe=* | --libex=* | --libe=*)
+ libexecdir=$ac_optarg ;;
+
+ -localstatedir | --localstatedir | --localstatedi | --localstated \
+ | --localstate | --localstat | --localsta | --localst \
+ | --locals | --local | --loca | --loc | --lo)
+ ac_prev=localstatedir ;;
+ -localstatedir=* | --localstatedir=* | --localstatedi=* | --localstated=* \
+ | --localstate=* | --localstat=* | --localsta=* | --localst=* \
+ | --locals=* | --local=* | --loca=* | --loc=* | --lo=*)
+ localstatedir=$ac_optarg ;;
+
+ -mandir | --mandir | --mandi | --mand | --man | --ma | --m)
+ ac_prev=mandir ;;
+ -mandir=* | --mandir=* | --mandi=* | --mand=* | --man=* | --ma=* | --m=*)
+ mandir=$ac_optarg ;;
+
+ -nfp | --nfp | --nf)
+ # Obsolete; use --without-fp.
+ with_fp=no ;;
+
+ -no-create | --no-create | --no-creat | --no-crea | --no-cre \
+ | --no-cr | --no-c | -n)
+ no_create=yes ;;
+
+ -no-recursion | --no-recursion | --no-recursio | --no-recursi \
+ | --no-recurs | --no-recur | --no-recu | --no-rec | --no-re | --no-r)
+ no_recursion=yes ;;
+
+ -oldincludedir | --oldincludedir | --oldincludedi | --oldincluded \
+ | --oldinclude | --oldinclud | --oldinclu | --oldincl | --oldinc \
+ | --oldin | --oldi | --old | --ol | --o)
+ ac_prev=oldincludedir ;;
+ -oldincludedir=* | --oldincludedir=* | --oldincludedi=* | --oldincluded=* \
+ | --oldinclude=* | --oldinclud=* | --oldinclu=* | --oldincl=* | --oldinc=* \
+ | --oldin=* | --oldi=* | --old=* | --ol=* | --o=*)
+ oldincludedir=$ac_optarg ;;
+
+ -prefix | --prefix | --prefi | --pref | --pre | --pr | --p)
+ ac_prev=prefix ;;
+ -prefix=* | --prefix=* | --prefi=* | --pref=* | --pre=* | --pr=* | --p=*)
+ prefix=$ac_optarg ;;
+
+ -program-prefix | --program-prefix | --program-prefi | --program-pref \
+ | --program-pre | --program-pr | --program-p)
+ ac_prev=program_prefix ;;
+ -program-prefix=* | --program-prefix=* | --program-prefi=* \
+ | --program-pref=* | --program-pre=* | --program-pr=* | --program-p=*)
+ program_prefix=$ac_optarg ;;
+
+ -program-suffix | --program-suffix | --program-suffi | --program-suff \
+ | --program-suf | --program-su | --program-s)
+ ac_prev=program_suffix ;;
+ -program-suffix=* | --program-suffix=* | --program-suffi=* \
+ | --program-suff=* | --program-suf=* | --program-su=* | --program-s=*)
+ program_suffix=$ac_optarg ;;
+
+ -program-transform-name | --program-transform-name \
+ | --program-transform-nam | --program-transform-na \
+ | --program-transform-n | --program-transform- \
+ | --program-transform | --program-transfor \
+ | --program-transfo | --program-transf \
+ | --program-trans | --program-tran \
+ | --progr-tra | --program-tr | --program-t)
+ ac_prev=program_transform_name ;;
+ -program-transform-name=* | --program-transform-name=* \
+ | --program-transform-nam=* | --program-transform-na=* \
+ | --program-transform-n=* | --program-transform-=* \
+ | --program-transform=* | --program-transfor=* \
+ | --program-transfo=* | --program-transf=* \
+ | --program-trans=* | --program-tran=* \
+ | --progr-tra=* | --program-tr=* | --program-t=*)
+ program_transform_name=$ac_optarg ;;
+
+ -q | -quiet | --quiet | --quie | --qui | --qu | --q \
+ | -silent | --silent | --silen | --sile | --sil)
+ silent=yes ;;
+
+ -sbindir | --sbindir | --sbindi | --sbind | --sbin | --sbi | --sb)
+ ac_prev=sbindir ;;
+ -sbindir=* | --sbindir=* | --sbindi=* | --sbind=* | --sbin=* \
+ | --sbi=* | --sb=*)
+ sbindir=$ac_optarg ;;
+
+ -sharedstatedir | --sharedstatedir | --sharedstatedi \
+ | --sharedstated | --sharedstate | --sharedstat | --sharedsta \
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+ | --sha | --sh)
+ ac_prev=sharedstatedir ;;
+ -sharedstatedir=* | --sharedstatedir=* | --sharedstatedi=* \
+ | --sharedstated=* | --sharedstate=* | --sharedstat=* | --sharedsta=* \
+ | --sharedst=* | --shareds=* | --shared=* | --share=* | --shar=* \
+ | --sha=* | --sh=*)
+ sharedstatedir=$ac_optarg ;;
+
+ -site | --site | --sit)
+ ac_prev=site ;;
+ -site=* | --site=* | --sit=*)
+ site=$ac_optarg ;;
+
+ -srcdir | --srcdir | --srcdi | --srcd | --src | --sr)
+ ac_prev=srcdir ;;
+ -srcdir=* | --srcdir=* | --srcdi=* | --srcd=* | --src=* | --sr=*)
+ srcdir=$ac_optarg ;;
+
+ -sysconfdir | --sysconfdir | --sysconfdi | --sysconfd | --sysconf \
+ | --syscon | --sysco | --sysc | --sys | --sy)
+ ac_prev=sysconfdir ;;
+ -sysconfdir=* | --sysconfdir=* | --sysconfdi=* | --sysconfd=* | --sysconf=* \
+ | --syscon=* | --sysco=* | --sysc=* | --sys=* | --sy=*)
+ sysconfdir=$ac_optarg ;;
+
+ -target | --target | --targe | --targ | --tar | --ta | --t)
+ ac_prev=target_alias ;;
+ -target=* | --target=* | --targe=* | --targ=* | --tar=* | --ta=* | --t=*)
+ target_alias=$ac_optarg ;;
+
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+ -version | --version | --versio | --versi | --vers | -V)
+ ac_init_version=: ;;
+
+ -with-* | --with-*)
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+ # Reject names that are not valid shell variable names.
+ expr "x$ac_package" : ".*[^-_$as_cr_alnum]" >/dev/null &&
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+ { (exit 1); exit 1; }; }
+ ac_package=`echo $ac_package| sed 's/-/_/g'`
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+ *) ac_optarg=yes ;;
+ esac
+ eval "with_$ac_package='$ac_optarg'" ;;
+
+ -without-* | --without-*)
+ ac_package=`expr "x$ac_option" : 'x-*without-\(.*\)'`
+ # Reject names that are not valid shell variable names.
+ expr "x$ac_package" : ".*[^-_$as_cr_alnum]" >/dev/null &&
+ { echo "$as_me: error: invalid package name: $ac_package" >&2
+ { (exit 1); exit 1; }; }
+ ac_package=`echo $ac_package | sed 's/-/_/g'`
+ eval "with_$ac_package=no" ;;
+
+ --x)
+ # Obsolete; use --with-x.
+ with_x=yes ;;
+
+ -x-includes | --x-includes | --x-include | --x-includ | --x-inclu \
+ | --x-incl | --x-inc | --x-in | --x-i)
+ ac_prev=x_includes ;;
+ -x-includes=* | --x-includes=* | --x-include=* | --x-includ=* | --x-inclu=* \
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+ x_includes=$ac_optarg ;;
+
+ -x-libraries | --x-libraries | --x-librarie | --x-librari \
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+ ac_prev=x_libraries ;;
+ -x-libraries=* | --x-libraries=* | --x-librarie=* | --x-librari=* \
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+ x_libraries=$ac_optarg ;;
+
+ -*) { echo "$as_me: error: unrecognized option: $ac_option
+Try \`$0 --help' for more information." >&2
+ { (exit 1); exit 1; }; }
+ ;;
+
+ *=*)
+ ac_envvar=`expr "x$ac_option" : 'x\([^=]*\)='`
+ # Reject names that are not valid shell variable names.
+ expr "x$ac_envvar" : ".*[^_$as_cr_alnum]" >/dev/null &&
+ { echo "$as_me: error: invalid variable name: $ac_envvar" >&2
+ { (exit 1); exit 1; }; }
+ ac_optarg=`echo "$ac_optarg" | sed "s/'/'\\\\\\\\''/g"`
+ eval "$ac_envvar='$ac_optarg'"
+ export $ac_envvar ;;
+
+ *)
+ # FIXME: should be removed in autoconf 3.0.
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+ expr "x$ac_option" : ".*[^-._$as_cr_alnum]" >/dev/null &&
+ echo "$as_me: WARNING: invalid host type: $ac_option" >&2
+ : ${build_alias=$ac_option} ${host_alias=$ac_option} ${target_alias=$ac_option}
+ ;;
+
+ esac
+done
+
+if test -n "$ac_prev"; then
+ ac_option=--`echo $ac_prev | sed 's/_/-/g'`
+ { echo "$as_me: error: missing argument to $ac_option" >&2
+ { (exit 1); exit 1; }; }
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+
+# Be sure to have absolute paths.
+for ac_var in exec_prefix prefix
+do
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+ case $ac_val in
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+ *) { echo "$as_me: error: expected an absolute directory name for --$ac_var: $ac_val" >&2
+ { (exit 1); exit 1; }; };;
+ esac
+done
+
+# Be sure to have absolute paths.
+for ac_var in bindir sbindir libexecdir datadir sysconfdir sharedstatedir \
+ localstatedir libdir includedir oldincludedir infodir mandir
+do
+ eval ac_val=$`echo $ac_var`
+ case $ac_val in
+ [\\/$]* | ?:[\\/]* ) ;;
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+ { (exit 1); exit 1; }; };;
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+
+# There might be people who depend on the old broken behavior: `$host'
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+ echo "$as_me: WARNING: If you wanted to set the --build type, don't use --host.
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+ elif test "x$build_alias" != "x$host_alias"; then
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+ fi
+fi
+
+ac_tool_prefix=
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+test "$silent" = yes && exec 6>/dev/null
+
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+# Find the source files, if location was not specified.
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+ # Try the directory containing this script, then its parent.
+ ac_confdir=`(dirname "$0") 2>/dev/null ||
+$as_expr X"$0" : 'X\(.*[^/]\)//*[^/][^/]*/*$' \| \
+ X"$0" : 'X\(//\)[^/]' \| \
+ X"$0" : 'X\(//\)$' \| \
+ X"$0" : 'X\(/\)' \| \
+ . : '\(.\)' 2>/dev/null ||
+echo X"$0" |
+ sed '/^X\(.*[^/]\)\/\/*[^/][^/]*\/*$/{ s//\1/; q; }
+ /^X\(\/\/\)[^/].*/{ s//\1/; q; }
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+ /^X\(\/\).*/{ s//\1/; q; }
+ s/.*/./; q'`
+ srcdir=$ac_confdir
+ if test ! -r $srcdir/$ac_unique_file; then
+ srcdir=..
+ fi
+else
+ ac_srcdir_defaulted=no
+fi
+if test ! -r $srcdir/$ac_unique_file; then
+ if test "$ac_srcdir_defaulted" = yes; then
+ { echo "$as_me: error: cannot find sources ($ac_unique_file) in $ac_confdir or .." >&2
+ { (exit 1); exit 1; }; }
+ else
+ { echo "$as_me: error: cannot find sources ($ac_unique_file) in $srcdir" >&2
+ { (exit 1); exit 1; }; }
+ fi
+fi
+(cd $srcdir && test -r ./$ac_unique_file) 2>/dev/null ||
+ { echo "$as_me: error: sources are in $srcdir, but \`cd $srcdir' does not work" >&2
+ { (exit 1); exit 1; }; }
+srcdir=`echo "$srcdir" | sed 's%\([^\\/]\)[\\/]*$%\1%'`
+ac_env_build_alias_set=${build_alias+set}
+ac_env_build_alias_value=$build_alias
+ac_cv_env_build_alias_set=${build_alias+set}
+ac_cv_env_build_alias_value=$build_alias
+ac_env_host_alias_set=${host_alias+set}
+ac_env_host_alias_value=$host_alias
+ac_cv_env_host_alias_set=${host_alias+set}
+ac_cv_env_host_alias_value=$host_alias
+ac_env_target_alias_set=${target_alias+set}
+ac_env_target_alias_value=$target_alias
+ac_cv_env_target_alias_set=${target_alias+set}
+ac_cv_env_target_alias_value=$target_alias
+ac_env_CC_set=${CC+set}
+ac_env_CC_value=$CC
+ac_cv_env_CC_set=${CC+set}
+ac_cv_env_CC_value=$CC
+ac_env_CFLAGS_set=${CFLAGS+set}
+ac_env_CFLAGS_value=$CFLAGS
+ac_cv_env_CFLAGS_set=${CFLAGS+set}
+ac_cv_env_CFLAGS_value=$CFLAGS
+ac_env_LDFLAGS_set=${LDFLAGS+set}
+ac_env_LDFLAGS_value=$LDFLAGS
+ac_cv_env_LDFLAGS_set=${LDFLAGS+set}
+ac_cv_env_LDFLAGS_value=$LDFLAGS
+ac_env_CPPFLAGS_set=${CPPFLAGS+set}
+ac_env_CPPFLAGS_value=$CPPFLAGS
+ac_cv_env_CPPFLAGS_set=${CPPFLAGS+set}
+ac_cv_env_CPPFLAGS_value=$CPPFLAGS
+ac_env_CPP_set=${CPP+set}
+ac_env_CPP_value=$CPP
+ac_cv_env_CPP_set=${CPP+set}
+ac_cv_env_CPP_value=$CPP
+
+#
+# Report the --help message.
+#
+if test "$ac_init_help" = "long"; then
+ # Omit some internal or obsolete options to make the list less imposing.
+ # This message is too long to be a string in the A/UX 3.1 sh.
+ cat <<_ACEOF
+\`configure' configures RNAhybrid 1.0 to adapt to many kinds of systems.
+
+Usage: $0 [OPTION]... [VAR=VALUE]...
+
+To assign environment variables (e.g., CC, CFLAGS...), specify them as
+VAR=VALUE. See below for descriptions of some of the useful variables.
+
+Defaults for the options are specified in brackets.
+
+Configuration:
+ -h, --help display this help and exit
+ --help=short display options specific to this package
+ --help=recursive display the short help of all the included packages
+ -V, --version display version information and exit
+ -q, --quiet, --silent do not print \`checking...' messages
+ --cache-file=FILE cache test results in FILE [disabled]
+ -C, --config-cache alias for \`--cache-file=config.cache'
+ -n, --no-create do not create output files
+ --srcdir=DIR find the sources in DIR [configure dir or \`..']
+
+_ACEOF
+
+ cat <<_ACEOF
+Installation directories:
+ --prefix=PREFIX install architecture-independent files in PREFIX
+ [$ac_default_prefix]
+ --exec-prefix=EPREFIX install architecture-dependent files in EPREFIX
+ [PREFIX]
+
+By default, \`make install' will install all the files in
+\`$ac_default_prefix/bin', \`$ac_default_prefix/lib' etc. You can specify
+an installation prefix other than \`$ac_default_prefix' using \`--prefix',
+for instance \`--prefix=\$HOME'.
+
+For better control, use the options below.
+
+Fine tuning of the installation directories:
+ --bindir=DIR user executables [EPREFIX/bin]
+ --sbindir=DIR system admin executables [EPREFIX/sbin]
+ --libexecdir=DIR program executables [EPREFIX/libexec]
+ --datadir=DIR read-only architecture-independent data [PREFIX/share]
+ --sysconfdir=DIR read-only single-machine data [PREFIX/etc]
+ --sharedstatedir=DIR modifiable architecture-independent data [PREFIX/com]
+ --localstatedir=DIR modifiable single-machine data [PREFIX/var]
+ --libdir=DIR object code libraries [EPREFIX/lib]
+ --includedir=DIR C header files [PREFIX/include]
+ --oldincludedir=DIR C header files for non-gcc [/usr/include]
+ --infodir=DIR info documentation [PREFIX/info]
+ --mandir=DIR man documentation [PREFIX/man]
+_ACEOF
+
+ cat <<\_ACEOF
+
+Program names:
+ --program-prefix=PREFIX prepend PREFIX to installed program names
+ --program-suffix=SUFFIX append SUFFIX to installed program names
+ --program-transform-name=PROGRAM run sed PROGRAM on installed program names
+_ACEOF
+fi
+
+if test -n "$ac_init_help"; then
+ case $ac_init_help in
+ short | recursive ) echo "Configuration of RNAhybrid 1.0:";;
+ esac
+ cat <<\_ACEOF
+
+Optional Features:
+ --disable-FEATURE do not include FEATURE (same as --enable-FEATURE=no)
+ --enable-FEATURE[=ARG] include FEATURE [ARG=yes]
+ --disable-dependency-tracking Speeds up one-time builds
+ --enable-dependency-tracking Do not reject slow dependency extractors
+
+Some influential environment variables:
+ CC C compiler command
+ CFLAGS C compiler flags
+ LDFLAGS linker flags, e.g. -L<lib dir> if you have libraries in a
+ nonstandard directory <lib dir>
+ CPPFLAGS C/C++ preprocessor flags, e.g. -I<include dir> if you have
+ headers in a nonstandard directory <include dir>
+ CPP C preprocessor
+
+Use these variables to override the choices made by `configure' or to help
+it to find libraries and programs with nonstandard names/locations.
+
+Report bugs to <marc at techfak.uni-bielefeld.de>.
+_ACEOF
+fi
+
+if test "$ac_init_help" = "recursive"; then
+ # If there are subdirs, report their specific --help.
+ ac_popdir=`pwd`
+ for ac_dir in : $ac_subdirs_all; do test "x$ac_dir" = x: && continue
+ test -d $ac_dir || continue
+ ac_builddir=.
+
+if test "$ac_dir" != .; then
+ ac_dir_suffix=/`echo "$ac_dir" | sed 's,^\.[\\/],,'`
+ # A "../" for each directory in $ac_dir_suffix.
+ ac_top_builddir=`echo "$ac_dir_suffix" | sed 's,/[^\\/]*,../,g'`
+else
+ ac_dir_suffix= ac_top_builddir=
+fi
+
+case $srcdir in
+ .) # No --srcdir option. We are building in place.
+ ac_srcdir=.
+ if test -z "$ac_top_builddir"; then
+ ac_top_srcdir=.
+ else
+ ac_top_srcdir=`echo $ac_top_builddir | sed 's,/$,,'`
+ fi ;;
+ [\\/]* | ?:[\\/]* ) # Absolute path.
+ ac_srcdir=$srcdir$ac_dir_suffix;
+ ac_top_srcdir=$srcdir ;;
+ *) # Relative path.
+ ac_srcdir=$ac_top_builddir$srcdir$ac_dir_suffix
+ ac_top_srcdir=$ac_top_builddir$srcdir ;;
+esac
+# Don't blindly perform a `cd "$ac_dir"/$ac_foo && pwd` since $ac_foo can be
+# absolute.
+ac_abs_builddir=`cd "$ac_dir" && cd $ac_builddir && pwd`
+ac_abs_top_builddir=`cd "$ac_dir" && cd ${ac_top_builddir}. && pwd`
+ac_abs_srcdir=`cd "$ac_dir" && cd $ac_srcdir && pwd`
+ac_abs_top_srcdir=`cd "$ac_dir" && cd $ac_top_srcdir && pwd`
+
+ cd $ac_dir
+ # Check for guested configure; otherwise get Cygnus style configure.
+ if test -f $ac_srcdir/configure.gnu; then
+ echo
+ $SHELL $ac_srcdir/configure.gnu --help=recursive
+ elif test -f $ac_srcdir/configure; then
+ echo
+ $SHELL $ac_srcdir/configure --help=recursive
+ elif test -f $ac_srcdir/configure.ac ||
+ test -f $ac_srcdir/configure.in; then
+ echo
+ $ac_configure --help
+ else
+ echo "$as_me: WARNING: no configuration information is in $ac_dir" >&2
+ fi
+ cd $ac_popdir
+ done
+fi
+
+test -n "$ac_init_help" && exit 0
+if $ac_init_version; then
+ cat <<\_ACEOF
+RNAhybrid configure 1.0
+generated by GNU Autoconf 2.57
+
+Copyright 1992, 1993, 1994, 1995, 1996, 1998, 1999, 2000, 2001, 2002
+Free Software Foundation, Inc.
+This configure script is free software; the Free Software Foundation
+gives unlimited permission to copy, distribute and modify it.
+_ACEOF
+ exit 0
+fi
+exec 5>config.log
+cat >&5 <<_ACEOF
+This file contains any messages produced by compilers while
+running configure, to aid debugging if configure makes a mistake.
+
+It was created by RNAhybrid $as_me 1.0, which was
+generated by GNU Autoconf 2.57. Invocation command line was
+
+ $ $0 $@
+
+_ACEOF
+{
+cat <<_ASUNAME
+## --------- ##
+## Platform. ##
+## --------- ##
+
+hostname = `(hostname || uname -n) 2>/dev/null | sed 1q`
+uname -m = `(uname -m) 2>/dev/null || echo unknown`
+uname -r = `(uname -r) 2>/dev/null || echo unknown`
+uname -s = `(uname -s) 2>/dev/null || echo unknown`
+uname -v = `(uname -v) 2>/dev/null || echo unknown`
+
+/usr/bin/uname -p = `(/usr/bin/uname -p) 2>/dev/null || echo unknown`
+/bin/uname -X = `(/bin/uname -X) 2>/dev/null || echo unknown`
+
+/bin/arch = `(/bin/arch) 2>/dev/null || echo unknown`
+/usr/bin/arch -k = `(/usr/bin/arch -k) 2>/dev/null || echo unknown`
+/usr/convex/getsysinfo = `(/usr/convex/getsysinfo) 2>/dev/null || echo unknown`
+hostinfo = `(hostinfo) 2>/dev/null || echo unknown`
+/bin/machine = `(/bin/machine) 2>/dev/null || echo unknown`
+/usr/bin/oslevel = `(/usr/bin/oslevel) 2>/dev/null || echo unknown`
+/bin/universe = `(/bin/universe) 2>/dev/null || echo unknown`
+
+_ASUNAME
+
+as_save_IFS=$IFS; IFS=$PATH_SEPARATOR
+for as_dir in $PATH
+do
+ IFS=$as_save_IFS
+ test -z "$as_dir" && as_dir=.
+ echo "PATH: $as_dir"
+done
+
+} >&5
+
+cat >&5 <<_ACEOF
+
+
+## ----------- ##
+## Core tests. ##
+## ----------- ##
+
+_ACEOF
+
+
+# Keep a trace of the command line.
+# Strip out --no-create and --no-recursion so they do not pile up.
+# Strip out --silent because we don't want to record it for future runs.
+# Also quote any args containing shell meta-characters.
+# Make two passes to allow for proper duplicate-argument suppression.
+ac_configure_args=
+ac_configure_args0=
+ac_configure_args1=
+ac_sep=
+ac_must_keep_next=false
+for ac_pass in 1 2
+do
+ for ac_arg
+ do
+ case $ac_arg in
+ -no-create | --no-c* | -n | -no-recursion | --no-r*) continue ;;
+ -q | -quiet | --quiet | --quie | --qui | --qu | --q \
+ | -silent | --silent | --silen | --sile | --sil)
+ continue ;;
+ *" "*|*" "*|*[\[\]\~\#\$\^\&\*\(\)\{\}\\\|\;\<\>\?\"\']*)
+ ac_arg=`echo "$ac_arg" | sed "s/'/'\\\\\\\\''/g"` ;;
+ esac
+ case $ac_pass in
+ 1) ac_configure_args0="$ac_configure_args0 '$ac_arg'" ;;
+ 2)
+ ac_configure_args1="$ac_configure_args1 '$ac_arg'"
+ if test $ac_must_keep_next = true; then
+ ac_must_keep_next=false # Got value, back to normal.
+ else
+ case $ac_arg in
+ *=* | --config-cache | -C | -disable-* | --disable-* \
+ | -enable-* | --enable-* | -gas | --g* | -nfp | --nf* \
+ | -q | -quiet | --q* | -silent | --sil* | -v | -verb* \
+ | -with-* | --with-* | -without-* | --without-* | --x)
+ case "$ac_configure_args0 " in
+ "$ac_configure_args1"*" '$ac_arg' "* ) continue ;;
+ esac
+ ;;
+ -* ) ac_must_keep_next=true ;;
+ esac
+ fi
+ ac_configure_args="$ac_configure_args$ac_sep'$ac_arg'"
+ # Get rid of the leading space.
+ ac_sep=" "
+ ;;
+ esac
+ done
+done
+$as_unset ac_configure_args0 || test "${ac_configure_args0+set}" != set || { ac_configure_args0=; export ac_configure_args0; }
+$as_unset ac_configure_args1 || test "${ac_configure_args1+set}" != set || { ac_configure_args1=; export ac_configure_args1; }
+
+# When interrupted or exit'd, cleanup temporary files, and complete
+# config.log. We remove comments because anyway the quotes in there
+# would cause problems or look ugly.
+# WARNING: Be sure not to use single quotes in there, as some shells,
+# such as our DU 5.0 friend, will then `close' the trap.
+trap 'exit_status=$?
+ # Save into config.log some information that might help in debugging.
+ {
+ echo
+
+ cat <<\_ASBOX
+## ---------------- ##
+## Cache variables. ##
+## ---------------- ##
+_ASBOX
+ echo
+ # The following way of writing the cache mishandles newlines in values,
+{
+ (set) 2>&1 |
+ case `(ac_space='"'"' '"'"'; set | grep ac_space) 2>&1` in
+ *ac_space=\ *)
+ sed -n \
+ "s/'"'"'/'"'"'\\\\'"'"''"'"'/g;
+ s/^\\([_$as_cr_alnum]*_cv_[_$as_cr_alnum]*\\)=\\(.*\\)/\\1='"'"'\\2'"'"'/p"
+ ;;
+ *)
+ sed -n \
+ "s/^\\([_$as_cr_alnum]*_cv_[_$as_cr_alnum]*\\)=\\(.*\\)/\\1=\\2/p"
+ ;;
+ esac;
+}
+ echo
+
+ cat <<\_ASBOX
+## ----------------- ##
+## Output variables. ##
+## ----------------- ##
+_ASBOX
+ echo
+ for ac_var in $ac_subst_vars
+ do
+ eval ac_val=$`echo $ac_var`
+ echo "$ac_var='"'"'$ac_val'"'"'"
+ done | sort
+ echo
+
+ if test -n "$ac_subst_files"; then
+ cat <<\_ASBOX
+## ------------- ##
+## Output files. ##
+## ------------- ##
+_ASBOX
+ echo
+ for ac_var in $ac_subst_files
+ do
+ eval ac_val=$`echo $ac_var`
+ echo "$ac_var='"'"'$ac_val'"'"'"
+ done | sort
+ echo
+ fi
+
+ if test -s confdefs.h; then
+ cat <<\_ASBOX
+## ----------- ##
+## confdefs.h. ##
+## ----------- ##
+_ASBOX
+ echo
+ sed "/^$/d" confdefs.h | sort
+ echo
+ fi
+ test "$ac_signal" != 0 &&
+ echo "$as_me: caught signal $ac_signal"
+ echo "$as_me: exit $exit_status"
+ } >&5
+ rm -f core core.* *.core &&
+ rm -rf conftest* confdefs* conf$$* $ac_clean_files &&
+ exit $exit_status
+ ' 0
+for ac_signal in 1 2 13 15; do
+ trap 'ac_signal='$ac_signal'; { (exit 1); exit 1; }' $ac_signal
+done
+ac_signal=0
+
+# confdefs.h avoids OS command line length limits that DEFS can exceed.
+rm -rf conftest* confdefs.h
+# AIX cpp loses on an empty file, so make sure it contains at least a newline.
+echo >confdefs.h
+
+# Predefined preprocessor variables.
+
+cat >>confdefs.h <<_ACEOF
+#define PACKAGE_NAME "$PACKAGE_NAME"
+_ACEOF
+
+
+cat >>confdefs.h <<_ACEOF
+#define PACKAGE_TARNAME "$PACKAGE_TARNAME"
+_ACEOF
+
+
+cat >>confdefs.h <<_ACEOF
+#define PACKAGE_VERSION "$PACKAGE_VERSION"
+_ACEOF
+
+
+cat >>confdefs.h <<_ACEOF
+#define PACKAGE_STRING "$PACKAGE_STRING"
+_ACEOF
+
+
+cat >>confdefs.h <<_ACEOF
+#define PACKAGE_BUGREPORT "$PACKAGE_BUGREPORT"
+_ACEOF
+
+
+# Let the site file select an alternate cache file if it wants to.
+# Prefer explicitly selected file to automatically selected ones.
+if test -z "$CONFIG_SITE"; then
+ if test "x$prefix" != xNONE; then
+ CONFIG_SITE="$prefix/share/config.site $prefix/etc/config.site"
+ else
+ CONFIG_SITE="$ac_default_prefix/share/config.site $ac_default_prefix/etc/config.site"
+ fi
+fi
+for ac_site_file in $CONFIG_SITE; do
+ if test -r "$ac_site_file"; then
+ { echo "$as_me:$LINENO: loading site script $ac_site_file" >&5
+echo "$as_me: loading site script $ac_site_file" >&6;}
+ sed 's/^/| /' "$ac_site_file" >&5
+ . "$ac_site_file"
+ fi
+done
+
+if test -r "$cache_file"; then
+ # Some versions of bash will fail to source /dev/null (special
+ # files actually), so we avoid doing that.
+ if test -f "$cache_file"; then
+ { echo "$as_me:$LINENO: loading cache $cache_file" >&5
+echo "$as_me: loading cache $cache_file" >&6;}
+ case $cache_file in
+ [\\/]* | ?:[\\/]* ) . $cache_file;;
+ *) . ./$cache_file;;
+ esac
+ fi
+else
+ { echo "$as_me:$LINENO: creating cache $cache_file" >&5
+echo "$as_me: creating cache $cache_file" >&6;}
+ >$cache_file
+fi
+
+# Check that the precious variables saved in the cache have kept the same
+# value.
+ac_cache_corrupted=false
+for ac_var in `(set) 2>&1 |
+ sed -n 's/^ac_env_\([a-zA-Z_0-9]*\)_set=.*/\1/p'`; do
+ eval ac_old_set=\$ac_cv_env_${ac_var}_set
+ eval ac_new_set=\$ac_env_${ac_var}_set
+ eval ac_old_val="\$ac_cv_env_${ac_var}_value"
+ eval ac_new_val="\$ac_env_${ac_var}_value"
+ case $ac_old_set,$ac_new_set in
+ set,)
+ { echo "$as_me:$LINENO: error: \`$ac_var' was set to \`$ac_old_val' in the previous run" >&5
+echo "$as_me: error: \`$ac_var' was set to \`$ac_old_val' in the previous run" >&2;}
+ ac_cache_corrupted=: ;;
+ ,set)
+ { echo "$as_me:$LINENO: error: \`$ac_var' was not set in the previous run" >&5
+echo "$as_me: error: \`$ac_var' was not set in the previous run" >&2;}
+ ac_cache_corrupted=: ;;
+ ,);;
+ *)
+ if test "x$ac_old_val" != "x$ac_new_val"; then
+ { echo "$as_me:$LINENO: error: \`$ac_var' has changed since the previous run:" >&5
+echo "$as_me: error: \`$ac_var' has changed since the previous run:" >&2;}
+ { echo "$as_me:$LINENO: former value: $ac_old_val" >&5
+echo "$as_me: former value: $ac_old_val" >&2;}
+ { echo "$as_me:$LINENO: current value: $ac_new_val" >&5
+echo "$as_me: current value: $ac_new_val" >&2;}
+ ac_cache_corrupted=:
+ fi;;
+ esac
+ # Pass precious variables to config.status.
+ if test "$ac_new_set" = set; then
+ case $ac_new_val in
+ *" "*|*" "*|*[\[\]\~\#\$\^\&\*\(\)\{\}\\\|\;\<\>\?\"\']*)
+ ac_arg=$ac_var=`echo "$ac_new_val" | sed "s/'/'\\\\\\\\''/g"` ;;
+ *) ac_arg=$ac_var=$ac_new_val ;;
+ esac
+ case " $ac_configure_args " in
+ *" '$ac_arg' "*) ;; # Avoid dups. Use of quotes ensures accuracy.
+ *) ac_configure_args="$ac_configure_args '$ac_arg'" ;;
+ esac
+ fi
+done
+if $ac_cache_corrupted; then
+ { echo "$as_me:$LINENO: error: changes in the environment can compromise the build" >&5
+echo "$as_me: error: changes in the environment can compromise the build" >&2;}
+ { { echo "$as_me:$LINENO: error: run \`make distclean' and/or \`rm $cache_file' and start over" >&5
+echo "$as_me: error: run \`make distclean' and/or \`rm $cache_file' and start over" >&2;}
+ { (exit 1); exit 1; }; }
+fi
+
+ac_ext=c
+ac_cpp='$CPP $CPPFLAGS'
+ac_compile='$CC -c $CFLAGS $CPPFLAGS conftest.$ac_ext >&5'
+ac_link='$CC -o conftest$ac_exeext $CFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5'
+ac_compiler_gnu=$ac_cv_c_compiler_gnu
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+am__api_version="1.7"
+ac_aux_dir=
+for ac_dir in $srcdir $srcdir/.. $srcdir/../..; do
+ if test -f $ac_dir/install-sh; then
+ ac_aux_dir=$ac_dir
+ ac_install_sh="$ac_aux_dir/install-sh -c"
+ break
+ elif test -f $ac_dir/install.sh; then
+ ac_aux_dir=$ac_dir
+ ac_install_sh="$ac_aux_dir/install.sh -c"
+ break
+ elif test -f $ac_dir/shtool; then
+ ac_aux_dir=$ac_dir
+ ac_install_sh="$ac_aux_dir/shtool install -c"
+ break
+ fi
+done
+if test -z "$ac_aux_dir"; then
+ { { echo "$as_me:$LINENO: error: cannot find install-sh or install.sh in $srcdir $srcdir/.. $srcdir/../.." >&5
+echo "$as_me: error: cannot find install-sh or install.sh in $srcdir $srcdir/.. $srcdir/../.." >&2;}
+ { (exit 1); exit 1; }; }
+fi
+ac_config_guess="$SHELL $ac_aux_dir/config.guess"
+ac_config_sub="$SHELL $ac_aux_dir/config.sub"
+ac_configure="$SHELL $ac_aux_dir/configure" # This should be Cygnus configure.
+
+# Find a good install program. We prefer a C program (faster),
+# so one script is as good as another. But avoid the broken or
+# incompatible versions:
+# SysV /etc/install, /usr/sbin/install
+# SunOS /usr/etc/install
+# IRIX /sbin/install
+# AIX /bin/install
+# AmigaOS /C/install, which installs bootblocks on floppy discs
+# AIX 4 /usr/bin/installbsd, which doesn't work without a -g flag
+# AFS /usr/afsws/bin/install, which mishandles nonexistent args
+# SVR4 /usr/ucb/install, which tries to use the nonexistent group "staff"
+# ./install, which can be erroneously created by make from ./install.sh.
+echo "$as_me:$LINENO: checking for a BSD-compatible install" >&5
+echo $ECHO_N "checking for a BSD-compatible install... $ECHO_C" >&6
+if test -z "$INSTALL"; then
+if test "${ac_cv_path_install+set}" = set; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+else
+ as_save_IFS=$IFS; IFS=$PATH_SEPARATOR
+for as_dir in $PATH
+do
+ IFS=$as_save_IFS
+ test -z "$as_dir" && as_dir=.
+ # Account for people who put trailing slashes in PATH elements.
+case $as_dir/ in
+ ./ | .// | /cC/* | \
+ /etc/* | /usr/sbin/* | /usr/etc/* | /sbin/* | /usr/afsws/bin/* | \
+ /usr/ucb/* ) ;;
+ *)
+ # OSF1 and SCO ODT 3.0 have their own names for install.
+ # Don't use installbsd from OSF since it installs stuff as root
+ # by default.
+ for ac_prog in ginstall scoinst install; do
+ for ac_exec_ext in '' $ac_executable_extensions; do
+ if $as_executable_p "$as_dir/$ac_prog$ac_exec_ext"; then
+ if test $ac_prog = install &&
+ grep dspmsg "$as_dir/$ac_prog$ac_exec_ext" >/dev/null 2>&1; then
+ # AIX install. It has an incompatible calling convention.
+ :
+ elif test $ac_prog = install &&
+ grep pwplus "$as_dir/$ac_prog$ac_exec_ext" >/dev/null 2>&1; then
+ # program-specific install script used by HP pwplus--don't use.
+ :
+ else
+ ac_cv_path_install="$as_dir/$ac_prog$ac_exec_ext -c"
+ break 3
+ fi
+ fi
+ done
+ done
+ ;;
+esac
+done
+
+
+fi
+ if test "${ac_cv_path_install+set}" = set; then
+ INSTALL=$ac_cv_path_install
+ else
+ # As a last resort, use the slow shell script. We don't cache a
+ # path for INSTALL within a source directory, because that will
+ # break other packages using the cache if that directory is
+ # removed, or if the path is relative.
+ INSTALL=$ac_install_sh
+ fi
+fi
+echo "$as_me:$LINENO: result: $INSTALL" >&5
+echo "${ECHO_T}$INSTALL" >&6
+
+# Use test -z because SunOS4 sh mishandles braces in ${var-val}.
+# It thinks the first close brace ends the variable substitution.
+test -z "$INSTALL_PROGRAM" && INSTALL_PROGRAM='${INSTALL}'
+
+test -z "$INSTALL_SCRIPT" && INSTALL_SCRIPT='${INSTALL}'
+
+test -z "$INSTALL_DATA" && INSTALL_DATA='${INSTALL} -m 644'
+
+echo "$as_me:$LINENO: checking whether build environment is sane" >&5
+echo $ECHO_N "checking whether build environment is sane... $ECHO_C" >&6
+# Just in case
+sleep 1
+echo timestamp > conftest.file
+# Do `set' in a subshell so we don't clobber the current shell's
+# arguments. Must try -L first in case configure is actually a
+# symlink; some systems play weird games with the mod time of symlinks
+# (eg FreeBSD returns the mod time of the symlink's containing
+# directory).
+if (
+ set X `ls -Lt $srcdir/configure conftest.file 2> /dev/null`
+ if test "$*" = "X"; then
+ # -L didn't work.
+ set X `ls -t $srcdir/configure conftest.file`
+ fi
+ rm -f conftest.file
+ if test "$*" != "X $srcdir/configure conftest.file" \
+ && test "$*" != "X conftest.file $srcdir/configure"; then
+
+ # If neither matched, then we have a broken ls. This can happen
+ # if, for instance, CONFIG_SHELL is bash and it inherits a
+ # broken ls alias from the environment. This has actually
+ # happened. Such a system could not be considered "sane".
+ { { echo "$as_me:$LINENO: error: ls -t appears to fail. Make sure there is not a broken
+alias in your environment" >&5
+echo "$as_me: error: ls -t appears to fail. Make sure there is not a broken
+alias in your environment" >&2;}
+ { (exit 1); exit 1; }; }
+ fi
+
+ test "$2" = conftest.file
+ )
+then
+ # Ok.
+ :
+else
+ { { echo "$as_me:$LINENO: error: newly created file is older than distributed files!
+Check your system clock" >&5
+echo "$as_me: error: newly created file is older than distributed files!
+Check your system clock" >&2;}
+ { (exit 1); exit 1; }; }
+fi
+echo "$as_me:$LINENO: result: yes" >&5
+echo "${ECHO_T}yes" >&6
+test "$program_prefix" != NONE &&
+ program_transform_name="s,^,$program_prefix,;$program_transform_name"
+# Use a double $ so make ignores it.
+test "$program_suffix" != NONE &&
+ program_transform_name="s,\$,$program_suffix,;$program_transform_name"
+# Double any \ or $. echo might interpret backslashes.
+# By default was `s,x,x', remove it if useless.
+cat <<\_ACEOF >conftest.sed
+s/[\\$]/&&/g;s/;s,x,x,$//
+_ACEOF
+program_transform_name=`echo $program_transform_name | sed -f conftest.sed`
+rm conftest.sed
+
+
+# expand $ac_aux_dir to an absolute path
+am_aux_dir=`cd $ac_aux_dir && pwd`
+
+test x"${MISSING+set}" = xset || MISSING="\${SHELL} $am_aux_dir/missing"
+# Use eval to expand $SHELL
+if eval "$MISSING --run true"; then
+ am_missing_run="$MISSING --run "
+else
+ am_missing_run=
+ { echo "$as_me:$LINENO: WARNING: \`missing' script is too old or missing" >&5
+echo "$as_me: WARNING: \`missing' script is too old or missing" >&2;}
+fi
+
+for ac_prog in gawk mawk nawk awk
+do
+ # Extract the first word of "$ac_prog", so it can be a program name with args.
+set dummy $ac_prog; ac_word=$2
+echo "$as_me:$LINENO: checking for $ac_word" >&5
+echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6
+if test "${ac_cv_prog_AWK+set}" = set; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+else
+ if test -n "$AWK"; then
+ ac_cv_prog_AWK="$AWK" # Let the user override the test.
+else
+as_save_IFS=$IFS; IFS=$PATH_SEPARATOR
+for as_dir in $PATH
+do
+ IFS=$as_save_IFS
+ test -z "$as_dir" && as_dir=.
+ for ac_exec_ext in '' $ac_executable_extensions; do
+ if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then
+ ac_cv_prog_AWK="$ac_prog"
+ echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5
+ break 2
+ fi
+done
+done
+
+fi
+fi
+AWK=$ac_cv_prog_AWK
+if test -n "$AWK"; then
+ echo "$as_me:$LINENO: result: $AWK" >&5
+echo "${ECHO_T}$AWK" >&6
+else
+ echo "$as_me:$LINENO: result: no" >&5
+echo "${ECHO_T}no" >&6
+fi
+
+ test -n "$AWK" && break
+done
+
+echo "$as_me:$LINENO: checking whether ${MAKE-make} sets \$(MAKE)" >&5
+echo $ECHO_N "checking whether ${MAKE-make} sets \$(MAKE)... $ECHO_C" >&6
+set dummy ${MAKE-make}; ac_make=`echo "$2" | sed 'y,./+-,__p_,'`
+if eval "test \"\${ac_cv_prog_make_${ac_make}_set+set}\" = set"; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+else
+ cat >conftest.make <<\_ACEOF
+all:
+ @echo 'ac_maketemp="$(MAKE)"'
+_ACEOF
+# GNU make sometimes prints "make[1]: Entering...", which would confuse us.
+eval `${MAKE-make} -f conftest.make 2>/dev/null | grep temp=`
+if test -n "$ac_maketemp"; then
+ eval ac_cv_prog_make_${ac_make}_set=yes
+else
+ eval ac_cv_prog_make_${ac_make}_set=no
+fi
+rm -f conftest.make
+fi
+if eval "test \"`echo '$ac_cv_prog_make_'${ac_make}_set`\" = yes"; then
+ echo "$as_me:$LINENO: result: yes" >&5
+echo "${ECHO_T}yes" >&6
+ SET_MAKE=
+else
+ echo "$as_me:$LINENO: result: no" >&5
+echo "${ECHO_T}no" >&6
+ SET_MAKE="MAKE=${MAKE-make}"
+fi
+
+rm -rf .tst 2>/dev/null
+mkdir .tst 2>/dev/null
+if test -d .tst; then
+ am__leading_dot=.
+else
+ am__leading_dot=_
+fi
+rmdir .tst 2>/dev/null
+
+ # test to see if srcdir already configured
+if test "`cd $srcdir && pwd`" != "`pwd`" &&
+ test -f $srcdir/config.status; then
+ { { echo "$as_me:$LINENO: error: source directory already configured; run \"make distclean\" there first" >&5
+echo "$as_me: error: source directory already configured; run \"make distclean\" there first" >&2;}
+ { (exit 1); exit 1; }; }
+fi
+
+# test whether we have cygpath
+if test -z "$CYGPATH_W"; then
+ if (cygpath --version) >/dev/null 2>/dev/null; then
+ CYGPATH_W='cygpath -w'
+ else
+ CYGPATH_W=echo
+ fi
+fi
+
+
+# Define the identity of the package.
+ PACKAGE='RNAhybrid'
+ VERSION='1.0'
+
+
+cat >>confdefs.h <<_ACEOF
+#define PACKAGE "$PACKAGE"
+_ACEOF
+
+
+cat >>confdefs.h <<_ACEOF
+#define VERSION "$VERSION"
+_ACEOF
+
+# Some tools Automake needs.
+
+ACLOCAL=${ACLOCAL-"${am_missing_run}aclocal-${am__api_version}"}
+
+
+AUTOCONF=${AUTOCONF-"${am_missing_run}autoconf"}
+
+
+AUTOMAKE=${AUTOMAKE-"${am_missing_run}automake-${am__api_version}"}
+
+
+AUTOHEADER=${AUTOHEADER-"${am_missing_run}autoheader"}
+
+
+MAKEINFO=${MAKEINFO-"${am_missing_run}makeinfo"}
+
+
+AMTAR=${AMTAR-"${am_missing_run}tar"}
+
+install_sh=${install_sh-"$am_aux_dir/install-sh"}
+
+# Installed binaries are usually stripped using `strip' when the user
+# run `make install-strip'. However `strip' might not be the right
+# tool to use in cross-compilation environments, therefore Automake
+# will honor the `STRIP' environment variable to overrule this program.
+if test "$cross_compiling" != no; then
+ if test -n "$ac_tool_prefix"; then
+ # Extract the first word of "${ac_tool_prefix}strip", so it can be a program name with args.
+set dummy ${ac_tool_prefix}strip; ac_word=$2
+echo "$as_me:$LINENO: checking for $ac_word" >&5
+echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6
+if test "${ac_cv_prog_STRIP+set}" = set; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+else
+ if test -n "$STRIP"; then
+ ac_cv_prog_STRIP="$STRIP" # Let the user override the test.
+else
+as_save_IFS=$IFS; IFS=$PATH_SEPARATOR
+for as_dir in $PATH
+do
+ IFS=$as_save_IFS
+ test -z "$as_dir" && as_dir=.
+ for ac_exec_ext in '' $ac_executable_extensions; do
+ if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then
+ ac_cv_prog_STRIP="${ac_tool_prefix}strip"
+ echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5
+ break 2
+ fi
+done
+done
+
+fi
+fi
+STRIP=$ac_cv_prog_STRIP
+if test -n "$STRIP"; then
+ echo "$as_me:$LINENO: result: $STRIP" >&5
+echo "${ECHO_T}$STRIP" >&6
+else
+ echo "$as_me:$LINENO: result: no" >&5
+echo "${ECHO_T}no" >&6
+fi
+
+fi
+if test -z "$ac_cv_prog_STRIP"; then
+ ac_ct_STRIP=$STRIP
+ # Extract the first word of "strip", so it can be a program name with args.
+set dummy strip; ac_word=$2
+echo "$as_me:$LINENO: checking for $ac_word" >&5
+echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6
+if test "${ac_cv_prog_ac_ct_STRIP+set}" = set; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+else
+ if test -n "$ac_ct_STRIP"; then
+ ac_cv_prog_ac_ct_STRIP="$ac_ct_STRIP" # Let the user override the test.
+else
+as_save_IFS=$IFS; IFS=$PATH_SEPARATOR
+for as_dir in $PATH
+do
+ IFS=$as_save_IFS
+ test -z "$as_dir" && as_dir=.
+ for ac_exec_ext in '' $ac_executable_extensions; do
+ if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then
+ ac_cv_prog_ac_ct_STRIP="strip"
+ echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5
+ break 2
+ fi
+done
+done
+
+ test -z "$ac_cv_prog_ac_ct_STRIP" && ac_cv_prog_ac_ct_STRIP=":"
+fi
+fi
+ac_ct_STRIP=$ac_cv_prog_ac_ct_STRIP
+if test -n "$ac_ct_STRIP"; then
+ echo "$as_me:$LINENO: result: $ac_ct_STRIP" >&5
+echo "${ECHO_T}$ac_ct_STRIP" >&6
+else
+ echo "$as_me:$LINENO: result: no" >&5
+echo "${ECHO_T}no" >&6
+fi
+
+ STRIP=$ac_ct_STRIP
+else
+ STRIP="$ac_cv_prog_STRIP"
+fi
+
+fi
+INSTALL_STRIP_PROGRAM="\${SHELL} \$(install_sh) -c -s"
+
+# We need awk for the "check" target. The system "awk" is bad on
+# some platforms.
+
+
+
+
+ ac_config_headers="$ac_config_headers config.h"
+
+
+ac_ext=c
+ac_cpp='$CPP $CPPFLAGS'
+ac_compile='$CC -c $CFLAGS $CPPFLAGS conftest.$ac_ext >&5'
+ac_link='$CC -o conftest$ac_exeext $CFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5'
+ac_compiler_gnu=$ac_cv_c_compiler_gnu
+if test -n "$ac_tool_prefix"; then
+ # Extract the first word of "${ac_tool_prefix}gcc", so it can be a program name with args.
+set dummy ${ac_tool_prefix}gcc; ac_word=$2
+echo "$as_me:$LINENO: checking for $ac_word" >&5
+echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6
+if test "${ac_cv_prog_CC+set}" = set; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+else
+ if test -n "$CC"; then
+ ac_cv_prog_CC="$CC" # Let the user override the test.
+else
+as_save_IFS=$IFS; IFS=$PATH_SEPARATOR
+for as_dir in $PATH
+do
+ IFS=$as_save_IFS
+ test -z "$as_dir" && as_dir=.
+ for ac_exec_ext in '' $ac_executable_extensions; do
+ if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then
+ ac_cv_prog_CC="${ac_tool_prefix}gcc"
+ echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5
+ break 2
+ fi
+done
+done
+
+fi
+fi
+CC=$ac_cv_prog_CC
+if test -n "$CC"; then
+ echo "$as_me:$LINENO: result: $CC" >&5
+echo "${ECHO_T}$CC" >&6
+else
+ echo "$as_me:$LINENO: result: no" >&5
+echo "${ECHO_T}no" >&6
+fi
+
+fi
+if test -z "$ac_cv_prog_CC"; then
+ ac_ct_CC=$CC
+ # Extract the first word of "gcc", so it can be a program name with args.
+set dummy gcc; ac_word=$2
+echo "$as_me:$LINENO: checking for $ac_word" >&5
+echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6
+if test "${ac_cv_prog_ac_ct_CC+set}" = set; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+else
+ if test -n "$ac_ct_CC"; then
+ ac_cv_prog_ac_ct_CC="$ac_ct_CC" # Let the user override the test.
+else
+as_save_IFS=$IFS; IFS=$PATH_SEPARATOR
+for as_dir in $PATH
+do
+ IFS=$as_save_IFS
+ test -z "$as_dir" && as_dir=.
+ for ac_exec_ext in '' $ac_executable_extensions; do
+ if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then
+ ac_cv_prog_ac_ct_CC="gcc"
+ echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5
+ break 2
+ fi
+done
+done
+
+fi
+fi
+ac_ct_CC=$ac_cv_prog_ac_ct_CC
+if test -n "$ac_ct_CC"; then
+ echo "$as_me:$LINENO: result: $ac_ct_CC" >&5
+echo "${ECHO_T}$ac_ct_CC" >&6
+else
+ echo "$as_me:$LINENO: result: no" >&5
+echo "${ECHO_T}no" >&6
+fi
+
+ CC=$ac_ct_CC
+else
+ CC="$ac_cv_prog_CC"
+fi
+
+if test -z "$CC"; then
+ if test -n "$ac_tool_prefix"; then
+ # Extract the first word of "${ac_tool_prefix}cc", so it can be a program name with args.
+set dummy ${ac_tool_prefix}cc; ac_word=$2
+echo "$as_me:$LINENO: checking for $ac_word" >&5
+echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6
+if test "${ac_cv_prog_CC+set}" = set; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+else
+ if test -n "$CC"; then
+ ac_cv_prog_CC="$CC" # Let the user override the test.
+else
+as_save_IFS=$IFS; IFS=$PATH_SEPARATOR
+for as_dir in $PATH
+do
+ IFS=$as_save_IFS
+ test -z "$as_dir" && as_dir=.
+ for ac_exec_ext in '' $ac_executable_extensions; do
+ if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then
+ ac_cv_prog_CC="${ac_tool_prefix}cc"
+ echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5
+ break 2
+ fi
+done
+done
+
+fi
+fi
+CC=$ac_cv_prog_CC
+if test -n "$CC"; then
+ echo "$as_me:$LINENO: result: $CC" >&5
+echo "${ECHO_T}$CC" >&6
+else
+ echo "$as_me:$LINENO: result: no" >&5
+echo "${ECHO_T}no" >&6
+fi
+
+fi
+if test -z "$ac_cv_prog_CC"; then
+ ac_ct_CC=$CC
+ # Extract the first word of "cc", so it can be a program name with args.
+set dummy cc; ac_word=$2
+echo "$as_me:$LINENO: checking for $ac_word" >&5
+echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6
+if test "${ac_cv_prog_ac_ct_CC+set}" = set; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+else
+ if test -n "$ac_ct_CC"; then
+ ac_cv_prog_ac_ct_CC="$ac_ct_CC" # Let the user override the test.
+else
+as_save_IFS=$IFS; IFS=$PATH_SEPARATOR
+for as_dir in $PATH
+do
+ IFS=$as_save_IFS
+ test -z "$as_dir" && as_dir=.
+ for ac_exec_ext in '' $ac_executable_extensions; do
+ if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then
+ ac_cv_prog_ac_ct_CC="cc"
+ echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5
+ break 2
+ fi
+done
+done
+
+fi
+fi
+ac_ct_CC=$ac_cv_prog_ac_ct_CC
+if test -n "$ac_ct_CC"; then
+ echo "$as_me:$LINENO: result: $ac_ct_CC" >&5
+echo "${ECHO_T}$ac_ct_CC" >&6
+else
+ echo "$as_me:$LINENO: result: no" >&5
+echo "${ECHO_T}no" >&6
+fi
+
+ CC=$ac_ct_CC
+else
+ CC="$ac_cv_prog_CC"
+fi
+
+fi
+if test -z "$CC"; then
+ # Extract the first word of "cc", so it can be a program name with args.
+set dummy cc; ac_word=$2
+echo "$as_me:$LINENO: checking for $ac_word" >&5
+echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6
+if test "${ac_cv_prog_CC+set}" = set; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+else
+ if test -n "$CC"; then
+ ac_cv_prog_CC="$CC" # Let the user override the test.
+else
+ ac_prog_rejected=no
+as_save_IFS=$IFS; IFS=$PATH_SEPARATOR
+for as_dir in $PATH
+do
+ IFS=$as_save_IFS
+ test -z "$as_dir" && as_dir=.
+ for ac_exec_ext in '' $ac_executable_extensions; do
+ if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then
+ if test "$as_dir/$ac_word$ac_exec_ext" = "/usr/ucb/cc"; then
+ ac_prog_rejected=yes
+ continue
+ fi
+ ac_cv_prog_CC="cc"
+ echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5
+ break 2
+ fi
+done
+done
+
+if test $ac_prog_rejected = yes; then
+ # We found a bogon in the path, so make sure we never use it.
+ set dummy $ac_cv_prog_CC
+ shift
+ if test $# != 0; then
+ # We chose a different compiler from the bogus one.
+ # However, it has the same basename, so the bogon will be chosen
+ # first if we set CC to just the basename; use the full file name.
+ shift
+ ac_cv_prog_CC="$as_dir/$ac_word${1+' '}$@"
+ fi
+fi
+fi
+fi
+CC=$ac_cv_prog_CC
+if test -n "$CC"; then
+ echo "$as_me:$LINENO: result: $CC" >&5
+echo "${ECHO_T}$CC" >&6
+else
+ echo "$as_me:$LINENO: result: no" >&5
+echo "${ECHO_T}no" >&6
+fi
+
+fi
+if test -z "$CC"; then
+ if test -n "$ac_tool_prefix"; then
+ for ac_prog in cl
+ do
+ # Extract the first word of "$ac_tool_prefix$ac_prog", so it can be a program name with args.
+set dummy $ac_tool_prefix$ac_prog; ac_word=$2
+echo "$as_me:$LINENO: checking for $ac_word" >&5
+echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6
+if test "${ac_cv_prog_CC+set}" = set; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+else
+ if test -n "$CC"; then
+ ac_cv_prog_CC="$CC" # Let the user override the test.
+else
+as_save_IFS=$IFS; IFS=$PATH_SEPARATOR
+for as_dir in $PATH
+do
+ IFS=$as_save_IFS
+ test -z "$as_dir" && as_dir=.
+ for ac_exec_ext in '' $ac_executable_extensions; do
+ if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then
+ ac_cv_prog_CC="$ac_tool_prefix$ac_prog"
+ echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5
+ break 2
+ fi
+done
+done
+
+fi
+fi
+CC=$ac_cv_prog_CC
+if test -n "$CC"; then
+ echo "$as_me:$LINENO: result: $CC" >&5
+echo "${ECHO_T}$CC" >&6
+else
+ echo "$as_me:$LINENO: result: no" >&5
+echo "${ECHO_T}no" >&6
+fi
+
+ test -n "$CC" && break
+ done
+fi
+if test -z "$CC"; then
+ ac_ct_CC=$CC
+ for ac_prog in cl
+do
+ # Extract the first word of "$ac_prog", so it can be a program name with args.
+set dummy $ac_prog; ac_word=$2
+echo "$as_me:$LINENO: checking for $ac_word" >&5
+echo $ECHO_N "checking for $ac_word... $ECHO_C" >&6
+if test "${ac_cv_prog_ac_ct_CC+set}" = set; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+else
+ if test -n "$ac_ct_CC"; then
+ ac_cv_prog_ac_ct_CC="$ac_ct_CC" # Let the user override the test.
+else
+as_save_IFS=$IFS; IFS=$PATH_SEPARATOR
+for as_dir in $PATH
+do
+ IFS=$as_save_IFS
+ test -z "$as_dir" && as_dir=.
+ for ac_exec_ext in '' $ac_executable_extensions; do
+ if $as_executable_p "$as_dir/$ac_word$ac_exec_ext"; then
+ ac_cv_prog_ac_ct_CC="$ac_prog"
+ echo "$as_me:$LINENO: found $as_dir/$ac_word$ac_exec_ext" >&5
+ break 2
+ fi
+done
+done
+
+fi
+fi
+ac_ct_CC=$ac_cv_prog_ac_ct_CC
+if test -n "$ac_ct_CC"; then
+ echo "$as_me:$LINENO: result: $ac_ct_CC" >&5
+echo "${ECHO_T}$ac_ct_CC" >&6
+else
+ echo "$as_me:$LINENO: result: no" >&5
+echo "${ECHO_T}no" >&6
+fi
+
+ test -n "$ac_ct_CC" && break
+done
+
+ CC=$ac_ct_CC
+fi
+
+fi
+
+
+test -z "$CC" && { { echo "$as_me:$LINENO: error: no acceptable C compiler found in \$PATH
+See \`config.log' for more details." >&5
+echo "$as_me: error: no acceptable C compiler found in \$PATH
+See \`config.log' for more details." >&2;}
+ { (exit 1); exit 1; }; }
+
+# Provide some information about the compiler.
+echo "$as_me:$LINENO:" \
+ "checking for C compiler version" >&5
+ac_compiler=`set X $ac_compile; echo $2`
+{ (eval echo "$as_me:$LINENO: \"$ac_compiler --version </dev/null >&5\"") >&5
+ (eval $ac_compiler --version </dev/null >&5) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); }
+{ (eval echo "$as_me:$LINENO: \"$ac_compiler -v </dev/null >&5\"") >&5
+ (eval $ac_compiler -v </dev/null >&5) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); }
+{ (eval echo "$as_me:$LINENO: \"$ac_compiler -V </dev/null >&5\"") >&5
+ (eval $ac_compiler -V </dev/null >&5) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); }
+
+cat >conftest.$ac_ext <<_ACEOF
+#line $LINENO "configure"
+/* confdefs.h. */
+_ACEOF
+cat confdefs.h >>conftest.$ac_ext
+cat >>conftest.$ac_ext <<_ACEOF
+/* end confdefs.h. */
+
+int
+main ()
+{
+
+ ;
+ return 0;
+}
+_ACEOF
+ac_clean_files_save=$ac_clean_files
+ac_clean_files="$ac_clean_files a.out a.exe b.out"
+# Try to create an executable without -o first, disregard a.out.
+# It will help us diagnose broken compilers, and finding out an intuition
+# of exeext.
+echo "$as_me:$LINENO: checking for C compiler default output" >&5
+echo $ECHO_N "checking for C compiler default output... $ECHO_C" >&6
+ac_link_default=`echo "$ac_link" | sed 's/ -o *conftest[^ ]*//'`
+if { (eval echo "$as_me:$LINENO: \"$ac_link_default\"") >&5
+ (eval $ac_link_default) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); }; then
+ # Find the output, starting from the most likely. This scheme is
+# not robust to junk in `.', hence go to wildcards (a.*) only as a last
+# resort.
+
+# Be careful to initialize this variable, since it used to be cached.
+# Otherwise an old cache value of `no' led to `EXEEXT = no' in a Makefile.
+ac_cv_exeext=
+# b.out is created by i960 compilers.
+for ac_file in a_out.exe a.exe conftest.exe a.out conftest a.* conftest.* b.out
+do
+ test -f "$ac_file" || continue
+ case $ac_file in
+ *.$ac_ext | *.xcoff | *.tds | *.d | *.pdb | *.xSYM | *.bb | *.bbg | *.o | *.obj )
+ ;;
+ conftest.$ac_ext )
+ # This is the source file.
+ ;;
+ [ab].out )
+ # We found the default executable, but exeext='' is most
+ # certainly right.
+ break;;
+ *.* )
+ ac_cv_exeext=`expr "$ac_file" : '[^.]*\(\..*\)'`
+ # FIXME: I believe we export ac_cv_exeext for Libtool,
+ # but it would be cool to find out if it's true. Does anybody
+ # maintain Libtool? --akim.
+ export ac_cv_exeext
+ break;;
+ * )
+ break;;
+ esac
+done
+else
+ echo "$as_me: failed program was:" >&5
+sed 's/^/| /' conftest.$ac_ext >&5
+
+{ { echo "$as_me:$LINENO: error: C compiler cannot create executables
+See \`config.log' for more details." >&5
+echo "$as_me: error: C compiler cannot create executables
+See \`config.log' for more details." >&2;}
+ { (exit 77); exit 77; }; }
+fi
+
+ac_exeext=$ac_cv_exeext
+echo "$as_me:$LINENO: result: $ac_file" >&5
+echo "${ECHO_T}$ac_file" >&6
+
+# Check the compiler produces executables we can run. If not, either
+# the compiler is broken, or we cross compile.
+echo "$as_me:$LINENO: checking whether the C compiler works" >&5
+echo $ECHO_N "checking whether the C compiler works... $ECHO_C" >&6
+# FIXME: These cross compiler hacks should be removed for Autoconf 3.0
+# If not cross compiling, check that we can run a simple program.
+if test "$cross_compiling" != yes; then
+ if { ac_try='./$ac_file'
+ { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5
+ (eval $ac_try) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); }; }; then
+ cross_compiling=no
+ else
+ if test "$cross_compiling" = maybe; then
+ cross_compiling=yes
+ else
+ { { echo "$as_me:$LINENO: error: cannot run C compiled programs.
+If you meant to cross compile, use \`--host'.
+See \`config.log' for more details." >&5
+echo "$as_me: error: cannot run C compiled programs.
+If you meant to cross compile, use \`--host'.
+See \`config.log' for more details." >&2;}
+ { (exit 1); exit 1; }; }
+ fi
+ fi
+fi
+echo "$as_me:$LINENO: result: yes" >&5
+echo "${ECHO_T}yes" >&6
+
+rm -f a.out a.exe conftest$ac_cv_exeext b.out
+ac_clean_files=$ac_clean_files_save
+# Check the compiler produces executables we can run. If not, either
+# the compiler is broken, or we cross compile.
+echo "$as_me:$LINENO: checking whether we are cross compiling" >&5
+echo $ECHO_N "checking whether we are cross compiling... $ECHO_C" >&6
+echo "$as_me:$LINENO: result: $cross_compiling" >&5
+echo "${ECHO_T}$cross_compiling" >&6
+
+echo "$as_me:$LINENO: checking for suffix of executables" >&5
+echo $ECHO_N "checking for suffix of executables... $ECHO_C" >&6
+if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5
+ (eval $ac_link) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); }; then
+ # If both `conftest.exe' and `conftest' are `present' (well, observable)
+# catch `conftest.exe'. For instance with Cygwin, `ls conftest' will
+# work properly (i.e., refer to `conftest.exe'), while it won't with
+# `rm'.
+for ac_file in conftest.exe conftest conftest.*; do
+ test -f "$ac_file" || continue
+ case $ac_file in
+ *.$ac_ext | *.xcoff | *.tds | *.d | *.pdb | *.xSYM | *.bb | *.bbg | *.o | *.obj ) ;;
+ *.* ) ac_cv_exeext=`expr "$ac_file" : '[^.]*\(\..*\)'`
+ export ac_cv_exeext
+ break;;
+ * ) break;;
+ esac
+done
+else
+ { { echo "$as_me:$LINENO: error: cannot compute suffix of executables: cannot compile and link
+See \`config.log' for more details." >&5
+echo "$as_me: error: cannot compute suffix of executables: cannot compile and link
+See \`config.log' for more details." >&2;}
+ { (exit 1); exit 1; }; }
+fi
+
+rm -f conftest$ac_cv_exeext
+echo "$as_me:$LINENO: result: $ac_cv_exeext" >&5
+echo "${ECHO_T}$ac_cv_exeext" >&6
+
+rm -f conftest.$ac_ext
+EXEEXT=$ac_cv_exeext
+ac_exeext=$EXEEXT
+echo "$as_me:$LINENO: checking for suffix of object files" >&5
+echo $ECHO_N "checking for suffix of object files... $ECHO_C" >&6
+if test "${ac_cv_objext+set}" = set; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+else
+ cat >conftest.$ac_ext <<_ACEOF
+#line $LINENO "configure"
+/* confdefs.h. */
+_ACEOF
+cat confdefs.h >>conftest.$ac_ext
+cat >>conftest.$ac_ext <<_ACEOF
+/* end confdefs.h. */
+
+int
+main ()
+{
+
+ ;
+ return 0;
+}
+_ACEOF
+rm -f conftest.o conftest.obj
+if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5
+ (eval $ac_compile) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); }; then
+ for ac_file in `(ls conftest.o conftest.obj; ls conftest.*) 2>/dev/null`; do
+ case $ac_file in
+ *.$ac_ext | *.xcoff | *.tds | *.d | *.pdb | *.xSYM | *.bb | *.bbg ) ;;
+ *) ac_cv_objext=`expr "$ac_file" : '.*\.\(.*\)'`
+ break;;
+ esac
+done
+else
+ echo "$as_me: failed program was:" >&5
+sed 's/^/| /' conftest.$ac_ext >&5
+
+{ { echo "$as_me:$LINENO: error: cannot compute suffix of object files: cannot compile
+See \`config.log' for more details." >&5
+echo "$as_me: error: cannot compute suffix of object files: cannot compile
+See \`config.log' for more details." >&2;}
+ { (exit 1); exit 1; }; }
+fi
+
+rm -f conftest.$ac_cv_objext conftest.$ac_ext
+fi
+echo "$as_me:$LINENO: result: $ac_cv_objext" >&5
+echo "${ECHO_T}$ac_cv_objext" >&6
+OBJEXT=$ac_cv_objext
+ac_objext=$OBJEXT
+echo "$as_me:$LINENO: checking whether we are using the GNU C compiler" >&5
+echo $ECHO_N "checking whether we are using the GNU C compiler... $ECHO_C" >&6
+if test "${ac_cv_c_compiler_gnu+set}" = set; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+else
+ cat >conftest.$ac_ext <<_ACEOF
+#line $LINENO "configure"
+/* confdefs.h. */
+_ACEOF
+cat confdefs.h >>conftest.$ac_ext
+cat >>conftest.$ac_ext <<_ACEOF
+/* end confdefs.h. */
+
+int
+main ()
+{
+#ifndef __GNUC__
+ choke me
+#endif
+
+ ;
+ return 0;
+}
+_ACEOF
+rm -f conftest.$ac_objext
+if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5
+ (eval $ac_compile) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); } &&
+ { ac_try='test -s conftest.$ac_objext'
+ { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5
+ (eval $ac_try) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); }; }; then
+ ac_compiler_gnu=yes
+else
+ echo "$as_me: failed program was:" >&5
+sed 's/^/| /' conftest.$ac_ext >&5
+
+ac_compiler_gnu=no
+fi
+rm -f conftest.$ac_objext conftest.$ac_ext
+ac_cv_c_compiler_gnu=$ac_compiler_gnu
+
+fi
+echo "$as_me:$LINENO: result: $ac_cv_c_compiler_gnu" >&5
+echo "${ECHO_T}$ac_cv_c_compiler_gnu" >&6
+GCC=`test $ac_compiler_gnu = yes && echo yes`
+ac_test_CFLAGS=${CFLAGS+set}
+ac_save_CFLAGS=$CFLAGS
+CFLAGS="-g"
+echo "$as_me:$LINENO: checking whether $CC accepts -g" >&5
+echo $ECHO_N "checking whether $CC accepts -g... $ECHO_C" >&6
+if test "${ac_cv_prog_cc_g+set}" = set; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+else
+ cat >conftest.$ac_ext <<_ACEOF
+#line $LINENO "configure"
+/* confdefs.h. */
+_ACEOF
+cat confdefs.h >>conftest.$ac_ext
+cat >>conftest.$ac_ext <<_ACEOF
+/* end confdefs.h. */
+
+int
+main ()
+{
+
+ ;
+ return 0;
+}
+_ACEOF
+rm -f conftest.$ac_objext
+if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5
+ (eval $ac_compile) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); } &&
+ { ac_try='test -s conftest.$ac_objext'
+ { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5
+ (eval $ac_try) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); }; }; then
+ ac_cv_prog_cc_g=yes
+else
+ echo "$as_me: failed program was:" >&5
+sed 's/^/| /' conftest.$ac_ext >&5
+
+ac_cv_prog_cc_g=no
+fi
+rm -f conftest.$ac_objext conftest.$ac_ext
+fi
+echo "$as_me:$LINENO: result: $ac_cv_prog_cc_g" >&5
+echo "${ECHO_T}$ac_cv_prog_cc_g" >&6
+if test "$ac_test_CFLAGS" = set; then
+ CFLAGS=$ac_save_CFLAGS
+elif test $ac_cv_prog_cc_g = yes; then
+ if test "$GCC" = yes; then
+ CFLAGS="-g -O2"
+ else
+ CFLAGS="-g"
+ fi
+else
+ if test "$GCC" = yes; then
+ CFLAGS="-O2"
+ else
+ CFLAGS=
+ fi
+fi
+echo "$as_me:$LINENO: checking for $CC option to accept ANSI C" >&5
+echo $ECHO_N "checking for $CC option to accept ANSI C... $ECHO_C" >&6
+if test "${ac_cv_prog_cc_stdc+set}" = set; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+else
+ ac_cv_prog_cc_stdc=no
+ac_save_CC=$CC
+cat >conftest.$ac_ext <<_ACEOF
+#line $LINENO "configure"
+/* confdefs.h. */
+_ACEOF
+cat confdefs.h >>conftest.$ac_ext
+cat >>conftest.$ac_ext <<_ACEOF
+/* end confdefs.h. */
+#include <stdarg.h>
+#include <stdio.h>
+#include <sys/types.h>
+#include <sys/stat.h>
+/* Most of the following tests are stolen from RCS 5.7's src/conf.sh. */
+struct buf { int x; };
+FILE * (*rcsopen) (struct buf *, struct stat *, int);
+static char *e (p, i)
+ char **p;
+ int i;
+{
+ return p[i];
+}
+static char *f (char * (*g) (char **, int), char **p, ...)
+{
+ char *s;
+ va_list v;
+ va_start (v,p);
+ s = g (p, va_arg (v,int));
+ va_end (v);
+ return s;
+}
+int test (int i, double x);
+struct s1 {int (*f) (int a);};
+struct s2 {int (*f) (double a);};
+int pairnames (int, char **, FILE *(*)(struct buf *, struct stat *, int), int, int);
+int argc;
+char **argv;
+int
+main ()
+{
+return f (e, argv, 0) != argv[0] || f (e, argv, 1) != argv[1];
+ ;
+ return 0;
+}
+_ACEOF
+# Don't try gcc -ansi; that turns off useful extensions and
+# breaks some systems' header files.
+# AIX -qlanglvl=ansi
+# Ultrix and OSF/1 -std1
+# HP-UX 10.20 and later -Ae
+# HP-UX older versions -Aa -D_HPUX_SOURCE
+# SVR4 -Xc -D__EXTENSIONS__
+for ac_arg in "" -qlanglvl=ansi -std1 -Ae "-Aa -D_HPUX_SOURCE" "-Xc -D__EXTENSIONS__"
+do
+ CC="$ac_save_CC $ac_arg"
+ rm -f conftest.$ac_objext
+if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5
+ (eval $ac_compile) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); } &&
+ { ac_try='test -s conftest.$ac_objext'
+ { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5
+ (eval $ac_try) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); }; }; then
+ ac_cv_prog_cc_stdc=$ac_arg
+break
+else
+ echo "$as_me: failed program was:" >&5
+sed 's/^/| /' conftest.$ac_ext >&5
+
+fi
+rm -f conftest.$ac_objext
+done
+rm -f conftest.$ac_ext conftest.$ac_objext
+CC=$ac_save_CC
+
+fi
+
+case "x$ac_cv_prog_cc_stdc" in
+ x|xno)
+ echo "$as_me:$LINENO: result: none needed" >&5
+echo "${ECHO_T}none needed" >&6 ;;
+ *)
+ echo "$as_me:$LINENO: result: $ac_cv_prog_cc_stdc" >&5
+echo "${ECHO_T}$ac_cv_prog_cc_stdc" >&6
+ CC="$CC $ac_cv_prog_cc_stdc" ;;
+esac
+
+# Some people use a C++ compiler to compile C. Since we use `exit',
+# in C++ we need to declare it. In case someone uses the same compiler
+# for both compiling C and C++ we need to have the C++ compiler decide
+# the declaration of exit, since it's the most demanding environment.
+cat >conftest.$ac_ext <<_ACEOF
+#ifndef __cplusplus
+ choke me
+#endif
+_ACEOF
+rm -f conftest.$ac_objext
+if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5
+ (eval $ac_compile) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); } &&
+ { ac_try='test -s conftest.$ac_objext'
+ { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5
+ (eval $ac_try) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); }; }; then
+ for ac_declaration in \
+ ''\
+ '#include <stdlib.h>' \
+ 'extern "C" void std::exit (int) throw (); using std::exit;' \
+ 'extern "C" void std::exit (int); using std::exit;' \
+ 'extern "C" void exit (int) throw ();' \
+ 'extern "C" void exit (int);' \
+ 'void exit (int);'
+do
+ cat >conftest.$ac_ext <<_ACEOF
+#line $LINENO "configure"
+/* confdefs.h. */
+_ACEOF
+cat confdefs.h >>conftest.$ac_ext
+cat >>conftest.$ac_ext <<_ACEOF
+/* end confdefs.h. */
+#include <stdlib.h>
+$ac_declaration
+int
+main ()
+{
+exit (42);
+ ;
+ return 0;
+}
+_ACEOF
+rm -f conftest.$ac_objext
+if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5
+ (eval $ac_compile) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); } &&
+ { ac_try='test -s conftest.$ac_objext'
+ { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5
+ (eval $ac_try) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); }; }; then
+ :
+else
+ echo "$as_me: failed program was:" >&5
+sed 's/^/| /' conftest.$ac_ext >&5
+
+continue
+fi
+rm -f conftest.$ac_objext conftest.$ac_ext
+ cat >conftest.$ac_ext <<_ACEOF
+#line $LINENO "configure"
+/* confdefs.h. */
+_ACEOF
+cat confdefs.h >>conftest.$ac_ext
+cat >>conftest.$ac_ext <<_ACEOF
+/* end confdefs.h. */
+$ac_declaration
+int
+main ()
+{
+exit (42);
+ ;
+ return 0;
+}
+_ACEOF
+rm -f conftest.$ac_objext
+if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5
+ (eval $ac_compile) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); } &&
+ { ac_try='test -s conftest.$ac_objext'
+ { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5
+ (eval $ac_try) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); }; }; then
+ break
+else
+ echo "$as_me: failed program was:" >&5
+sed 's/^/| /' conftest.$ac_ext >&5
+
+fi
+rm -f conftest.$ac_objext conftest.$ac_ext
+done
+rm -f conftest*
+if test -n "$ac_declaration"; then
+ echo '#ifdef __cplusplus' >>confdefs.h
+ echo $ac_declaration >>confdefs.h
+ echo '#endif' >>confdefs.h
+fi
+
+else
+ echo "$as_me: failed program was:" >&5
+sed 's/^/| /' conftest.$ac_ext >&5
+
+fi
+rm -f conftest.$ac_objext conftest.$ac_ext
+ac_ext=c
+ac_cpp='$CPP $CPPFLAGS'
+ac_compile='$CC -c $CFLAGS $CPPFLAGS conftest.$ac_ext >&5'
+ac_link='$CC -o conftest$ac_exeext $CFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5'
+ac_compiler_gnu=$ac_cv_c_compiler_gnu
+DEPDIR="${am__leading_dot}deps"
+
+ ac_config_commands="$ac_config_commands depfiles"
+
+
+am_make=${MAKE-make}
+cat > confinc << 'END'
+doit:
+ @echo done
+END
+# If we don't find an include directive, just comment out the code.
+echo "$as_me:$LINENO: checking for style of include used by $am_make" >&5
+echo $ECHO_N "checking for style of include used by $am_make... $ECHO_C" >&6
+am__include="#"
+am__quote=
+_am_result=none
+# First try GNU make style include.
+echo "include confinc" > confmf
+# We grep out `Entering directory' and `Leaving directory'
+# messages which can occur if `w' ends up in MAKEFLAGS.
+# In particular we don't look at `^make:' because GNU make might
+# be invoked under some other name (usually "gmake"), in which
+# case it prints its new name instead of `make'.
+if test "`$am_make -s -f confmf 2> /dev/null | grep -v 'ing directory'`" = "done"; then
+ am__include=include
+ am__quote=
+ _am_result=GNU
+fi
+# Now try BSD make style include.
+if test "$am__include" = "#"; then
+ echo '.include "confinc"' > confmf
+ if test "`$am_make -s -f confmf 2> /dev/null`" = "done"; then
+ am__include=.include
+ am__quote="\""
+ _am_result=BSD
+ fi
+fi
+
+
+echo "$as_me:$LINENO: result: $_am_result" >&5
+echo "${ECHO_T}$_am_result" >&6
+rm -f confinc confmf
+
+# Check whether --enable-dependency-tracking or --disable-dependency-tracking was given.
+if test "${enable_dependency_tracking+set}" = set; then
+ enableval="$enable_dependency_tracking"
+
+fi;
+if test "x$enable_dependency_tracking" != xno; then
+ am_depcomp="$ac_aux_dir/depcomp"
+ AMDEPBACKSLASH='\'
+fi
+
+
+if test "x$enable_dependency_tracking" != xno; then
+ AMDEP_TRUE=
+ AMDEP_FALSE='#'
+else
+ AMDEP_TRUE='#'
+ AMDEP_FALSE=
+fi
+
+
+
+
+depcc="$CC" am_compiler_list=
+
+echo "$as_me:$LINENO: checking dependency style of $depcc" >&5
+echo $ECHO_N "checking dependency style of $depcc... $ECHO_C" >&6
+if test "${am_cv_CC_dependencies_compiler_type+set}" = set; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+else
+ if test -z "$AMDEP_TRUE" && test -f "$am_depcomp"; then
+ # We make a subdir and do the tests there. Otherwise we can end up
+ # making bogus files that we don't know about and never remove. For
+ # instance it was reported that on HP-UX the gcc test will end up
+ # making a dummy file named `D' -- because `-MD' means `put the output
+ # in D'.
+ mkdir conftest.dir
+ # Copy depcomp to subdir because otherwise we won't find it if we're
+ # using a relative directory.
+ cp "$am_depcomp" conftest.dir
+ cd conftest.dir
+
+ am_cv_CC_dependencies_compiler_type=none
+ if test "$am_compiler_list" = ""; then
+ am_compiler_list=`sed -n 's/^#*\([a-zA-Z0-9]*\))$/\1/p' < ./depcomp`
+ fi
+ for depmode in $am_compiler_list; do
+ # We need to recreate these files for each test, as the compiler may
+ # overwrite some of them when testing with obscure command lines.
+ # This happens at least with the AIX C compiler.
+ echo '#include "conftest.h"' > conftest.c
+ echo 'int i;' > conftest.h
+ echo "${am__include} ${am__quote}conftest.Po${am__quote}" > confmf
+
+ case $depmode in
+ nosideeffect)
+ # after this tag, mechanisms are not by side-effect, so they'll
+ # only be used when explicitly requested
+ if test "x$enable_dependency_tracking" = xyes; then
+ continue
+ else
+ break
+ fi
+ ;;
+ none) break ;;
+ esac
+ # We check with `-c' and `-o' for the sake of the "dashmstdout"
+ # mode. It turns out that the SunPro C++ compiler does not properly
+ # handle `-M -o', and we need to detect this.
+ if depmode=$depmode \
+ source=conftest.c object=conftest.o \
+ depfile=conftest.Po tmpdepfile=conftest.TPo \
+ $SHELL ./depcomp $depcc -c -o conftest.o conftest.c \
+ >/dev/null 2>conftest.err &&
+ grep conftest.h conftest.Po > /dev/null 2>&1 &&
+ ${MAKE-make} -s -f confmf > /dev/null 2>&1; then
+ # icc doesn't choke on unknown options, it will just issue warnings
+ # (even with -Werror). So we grep stderr for any message
+ # that says an option was ignored.
+ if grep 'ignoring option' conftest.err >/dev/null 2>&1; then :; else
+ am_cv_CC_dependencies_compiler_type=$depmode
+ break
+ fi
+ fi
+ done
+
+ cd ..
+ rm -rf conftest.dir
+else
+ am_cv_CC_dependencies_compiler_type=none
+fi
+
+fi
+echo "$as_me:$LINENO: result: $am_cv_CC_dependencies_compiler_type" >&5
+echo "${ECHO_T}$am_cv_CC_dependencies_compiler_type" >&6
+CCDEPMODE=depmode=$am_cv_CC_dependencies_compiler_type
+
+
+
+if
+ test "x$enable_dependency_tracking" != xno \
+ && test "$am_cv_CC_dependencies_compiler_type" = gcc3; then
+ am__fastdepCC_TRUE=
+ am__fastdepCC_FALSE='#'
+else
+ am__fastdepCC_TRUE='#'
+ am__fastdepCC_FALSE=
+fi
+
+
+ac_ext=c
+ac_cpp='$CPP $CPPFLAGS'
+ac_compile='$CC -c $CFLAGS $CPPFLAGS conftest.$ac_ext >&5'
+ac_link='$CC -o conftest$ac_exeext $CFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5'
+ac_compiler_gnu=$ac_cv_c_compiler_gnu
+
+
+
+
+echo "$as_me:$LINENO: checking for log in -lm" >&5
+echo $ECHO_N "checking for log in -lm... $ECHO_C" >&6
+if test "${ac_cv_lib_m_log+set}" = set; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+else
+ ac_check_lib_save_LIBS=$LIBS
+LIBS="-lm $LIBS"
+cat >conftest.$ac_ext <<_ACEOF
+#line $LINENO "configure"
+/* confdefs.h. */
+_ACEOF
+cat confdefs.h >>conftest.$ac_ext
+cat >>conftest.$ac_ext <<_ACEOF
+/* end confdefs.h. */
+
+/* Override any gcc2 internal prototype to avoid an error. */
+#ifdef __cplusplus
+extern "C"
+#endif
+/* We use char because int might match the return type of a gcc2
+ builtin and then its argument prototype would still apply. */
+char log ();
+int
+main ()
+{
+log ();
+ ;
+ return 0;
+}
+_ACEOF
+rm -f conftest.$ac_objext conftest$ac_exeext
+if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5
+ (eval $ac_link) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); } &&
+ { ac_try='test -s conftest$ac_exeext'
+ { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5
+ (eval $ac_try) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); }; }; then
+ ac_cv_lib_m_log=yes
+else
+ echo "$as_me: failed program was:" >&5
+sed 's/^/| /' conftest.$ac_ext >&5
+
+ac_cv_lib_m_log=no
+fi
+rm -f conftest.$ac_objext conftest$ac_exeext conftest.$ac_ext
+LIBS=$ac_check_lib_save_LIBS
+fi
+echo "$as_me:$LINENO: result: $ac_cv_lib_m_log" >&5
+echo "${ECHO_T}$ac_cv_lib_m_log" >&6
+if test $ac_cv_lib_m_log = yes; then
+ cat >>confdefs.h <<_ACEOF
+#define HAVE_LIBM 1
+_ACEOF
+
+ LIBS="-lm $LIBS"
+
+else
+ { { echo "$as_me:$LINENO: error: math library is missing" >&5
+echo "$as_me: error: math library is missing" >&2;}
+ { (exit 1); exit 1; }; }
+fi
+
+
+echo "$as_me:$LINENO: checking for g2_open_vd in -lg2" >&5
+echo $ECHO_N "checking for g2_open_vd in -lg2... $ECHO_C" >&6
+if test "${ac_cv_lib_g2_g2_open_vd+set}" = set; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+else
+ ac_check_lib_save_LIBS=$LIBS
+LIBS="-lg2 $LIBS"
+cat >conftest.$ac_ext <<_ACEOF
+#line $LINENO "configure"
+/* confdefs.h. */
+_ACEOF
+cat confdefs.h >>conftest.$ac_ext
+cat >>conftest.$ac_ext <<_ACEOF
+/* end confdefs.h. */
+
+/* Override any gcc2 internal prototype to avoid an error. */
+#ifdef __cplusplus
+extern "C"
+#endif
+/* We use char because int might match the return type of a gcc2
+ builtin and then its argument prototype would still apply. */
+char g2_open_vd ();
+int
+main ()
+{
+g2_open_vd ();
+ ;
+ return 0;
+}
+_ACEOF
+rm -f conftest.$ac_objext conftest$ac_exeext
+if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5
+ (eval $ac_link) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); } &&
+ { ac_try='test -s conftest$ac_exeext'
+ { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5
+ (eval $ac_try) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); }; }; then
+ ac_cv_lib_g2_g2_open_vd=yes
+else
+ echo "$as_me: failed program was:" >&5
+sed 's/^/| /' conftest.$ac_ext >&5
+
+ac_cv_lib_g2_g2_open_vd=no
+fi
+rm -f conftest.$ac_objext conftest$ac_exeext conftest.$ac_ext
+LIBS=$ac_check_lib_save_LIBS
+fi
+echo "$as_me:$LINENO: result: $ac_cv_lib_g2_g2_open_vd" >&5
+echo "${ECHO_T}$ac_cv_lib_g2_g2_open_vd" >&6
+if test $ac_cv_lib_g2_g2_open_vd = yes; then
+ cat >>confdefs.h <<_ACEOF
+#define HAVE_LIBG2 1
+_ACEOF
+
+ LIBS="-lg2 $LIBS"
+
+else
+ { echo "$as_me:$LINENO: WARNING: libg2.a is missing. You can download it at http://g2.sourceforge.net/" >&5
+echo "$as_me: WARNING: libg2.a is missing. You can download it at http://g2.sourceforge.net/" >&2;}
+fi
+
+
+echo "$as_me:$LINENO: checking for gdImageLine in -lgd" >&5
+echo $ECHO_N "checking for gdImageLine in -lgd... $ECHO_C" >&6
+if test "${ac_cv_lib_gd_gdImageLine+set}" = set; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+else
+ ac_check_lib_save_LIBS=$LIBS
+LIBS="-lgd $LIBS"
+cat >conftest.$ac_ext <<_ACEOF
+#line $LINENO "configure"
+/* confdefs.h. */
+_ACEOF
+cat confdefs.h >>conftest.$ac_ext
+cat >>conftest.$ac_ext <<_ACEOF
+/* end confdefs.h. */
+
+/* Override any gcc2 internal prototype to avoid an error. */
+#ifdef __cplusplus
+extern "C"
+#endif
+/* We use char because int might match the return type of a gcc2
+ builtin and then its argument prototype would still apply. */
+char gdImageLine ();
+int
+main ()
+{
+gdImageLine ();
+ ;
+ return 0;
+}
+_ACEOF
+rm -f conftest.$ac_objext conftest$ac_exeext
+if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5
+ (eval $ac_link) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); } &&
+ { ac_try='test -s conftest$ac_exeext'
+ { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5
+ (eval $ac_try) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); }; }; then
+ ac_cv_lib_gd_gdImageLine=yes
+else
+ echo "$as_me: failed program was:" >&5
+sed 's/^/| /' conftest.$ac_ext >&5
+
+ac_cv_lib_gd_gdImageLine=no
+fi
+rm -f conftest.$ac_objext conftest$ac_exeext conftest.$ac_ext
+LIBS=$ac_check_lib_save_LIBS
+fi
+echo "$as_me:$LINENO: result: $ac_cv_lib_gd_gdImageLine" >&5
+echo "${ECHO_T}$ac_cv_lib_gd_gdImageLine" >&6
+if test $ac_cv_lib_gd_gdImageLine = yes; then
+ cat >>confdefs.h <<_ACEOF
+#define HAVE_LIBGD 1
+_ACEOF
+
+ LIBS="-lgd $LIBS"
+
+fi
+
+
+ac_ext=c
+ac_cpp='$CPP $CPPFLAGS'
+ac_compile='$CC -c $CFLAGS $CPPFLAGS conftest.$ac_ext >&5'
+ac_link='$CC -o conftest$ac_exeext $CFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5'
+ac_compiler_gnu=$ac_cv_c_compiler_gnu
+echo "$as_me:$LINENO: checking how to run the C preprocessor" >&5
+echo $ECHO_N "checking how to run the C preprocessor... $ECHO_C" >&6
+# On Suns, sometimes $CPP names a directory.
+if test -n "$CPP" && test -d "$CPP"; then
+ CPP=
+fi
+if test -z "$CPP"; then
+ if test "${ac_cv_prog_CPP+set}" = set; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+else
+ # Double quotes because CPP needs to be expanded
+ for CPP in "$CC -E" "$CC -E -traditional-cpp" "/lib/cpp"
+ do
+ ac_preproc_ok=false
+for ac_c_preproc_warn_flag in '' yes
+do
+ # Use a header file that comes with gcc, so configuring glibc
+ # with a fresh cross-compiler works.
+ # Prefer <limits.h> to <assert.h> if __STDC__ is defined, since
+ # <limits.h> exists even on freestanding compilers.
+ # On the NeXT, cc -E runs the code through the compiler's parser,
+ # not just through cpp. "Syntax error" is here to catch this case.
+ cat >conftest.$ac_ext <<_ACEOF
+#line $LINENO "configure"
+/* confdefs.h. */
+_ACEOF
+cat confdefs.h >>conftest.$ac_ext
+cat >>conftest.$ac_ext <<_ACEOF
+/* end confdefs.h. */
+#ifdef __STDC__
+# include <limits.h>
+#else
+# include <assert.h>
+#endif
+ Syntax error
+_ACEOF
+if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5
+ (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1
+ ac_status=$?
+ grep -v '^ *+' conftest.er1 >conftest.err
+ rm -f conftest.er1
+ cat conftest.err >&5
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); } >/dev/null; then
+ if test -s conftest.err; then
+ ac_cpp_err=$ac_c_preproc_warn_flag
+ else
+ ac_cpp_err=
+ fi
+else
+ ac_cpp_err=yes
+fi
+if test -z "$ac_cpp_err"; then
+ :
+else
+ echo "$as_me: failed program was:" >&5
+sed 's/^/| /' conftest.$ac_ext >&5
+
+ # Broken: fails on valid input.
+continue
+fi
+rm -f conftest.err conftest.$ac_ext
+
+ # OK, works on sane cases. Now check whether non-existent headers
+ # can be detected and how.
+ cat >conftest.$ac_ext <<_ACEOF
+#line $LINENO "configure"
+/* confdefs.h. */
+_ACEOF
+cat confdefs.h >>conftest.$ac_ext
+cat >>conftest.$ac_ext <<_ACEOF
+/* end confdefs.h. */
+#include <ac_nonexistent.h>
+_ACEOF
+if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5
+ (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1
+ ac_status=$?
+ grep -v '^ *+' conftest.er1 >conftest.err
+ rm -f conftest.er1
+ cat conftest.err >&5
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); } >/dev/null; then
+ if test -s conftest.err; then
+ ac_cpp_err=$ac_c_preproc_warn_flag
+ else
+ ac_cpp_err=
+ fi
+else
+ ac_cpp_err=yes
+fi
+if test -z "$ac_cpp_err"; then
+ # Broken: success on invalid input.
+continue
+else
+ echo "$as_me: failed program was:" >&5
+sed 's/^/| /' conftest.$ac_ext >&5
+
+ # Passes both tests.
+ac_preproc_ok=:
+break
+fi
+rm -f conftest.err conftest.$ac_ext
+
+done
+# Because of `break', _AC_PREPROC_IFELSE's cleaning code was skipped.
+rm -f conftest.err conftest.$ac_ext
+if $ac_preproc_ok; then
+ break
+fi
+
+ done
+ ac_cv_prog_CPP=$CPP
+
+fi
+ CPP=$ac_cv_prog_CPP
+else
+ ac_cv_prog_CPP=$CPP
+fi
+echo "$as_me:$LINENO: result: $CPP" >&5
+echo "${ECHO_T}$CPP" >&6
+ac_preproc_ok=false
+for ac_c_preproc_warn_flag in '' yes
+do
+ # Use a header file that comes with gcc, so configuring glibc
+ # with a fresh cross-compiler works.
+ # Prefer <limits.h> to <assert.h> if __STDC__ is defined, since
+ # <limits.h> exists even on freestanding compilers.
+ # On the NeXT, cc -E runs the code through the compiler's parser,
+ # not just through cpp. "Syntax error" is here to catch this case.
+ cat >conftest.$ac_ext <<_ACEOF
+#line $LINENO "configure"
+/* confdefs.h. */
+_ACEOF
+cat confdefs.h >>conftest.$ac_ext
+cat >>conftest.$ac_ext <<_ACEOF
+/* end confdefs.h. */
+#ifdef __STDC__
+# include <limits.h>
+#else
+# include <assert.h>
+#endif
+ Syntax error
+_ACEOF
+if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5
+ (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1
+ ac_status=$?
+ grep -v '^ *+' conftest.er1 >conftest.err
+ rm -f conftest.er1
+ cat conftest.err >&5
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); } >/dev/null; then
+ if test -s conftest.err; then
+ ac_cpp_err=$ac_c_preproc_warn_flag
+ else
+ ac_cpp_err=
+ fi
+else
+ ac_cpp_err=yes
+fi
+if test -z "$ac_cpp_err"; then
+ :
+else
+ echo "$as_me: failed program was:" >&5
+sed 's/^/| /' conftest.$ac_ext >&5
+
+ # Broken: fails on valid input.
+continue
+fi
+rm -f conftest.err conftest.$ac_ext
+
+ # OK, works on sane cases. Now check whether non-existent headers
+ # can be detected and how.
+ cat >conftest.$ac_ext <<_ACEOF
+#line $LINENO "configure"
+/* confdefs.h. */
+_ACEOF
+cat confdefs.h >>conftest.$ac_ext
+cat >>conftest.$ac_ext <<_ACEOF
+/* end confdefs.h. */
+#include <ac_nonexistent.h>
+_ACEOF
+if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5
+ (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1
+ ac_status=$?
+ grep -v '^ *+' conftest.er1 >conftest.err
+ rm -f conftest.er1
+ cat conftest.err >&5
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); } >/dev/null; then
+ if test -s conftest.err; then
+ ac_cpp_err=$ac_c_preproc_warn_flag
+ else
+ ac_cpp_err=
+ fi
+else
+ ac_cpp_err=yes
+fi
+if test -z "$ac_cpp_err"; then
+ # Broken: success on invalid input.
+continue
+else
+ echo "$as_me: failed program was:" >&5
+sed 's/^/| /' conftest.$ac_ext >&5
+
+ # Passes both tests.
+ac_preproc_ok=:
+break
+fi
+rm -f conftest.err conftest.$ac_ext
+
+done
+# Because of `break', _AC_PREPROC_IFELSE's cleaning code was skipped.
+rm -f conftest.err conftest.$ac_ext
+if $ac_preproc_ok; then
+ :
+else
+ { { echo "$as_me:$LINENO: error: C preprocessor \"$CPP\" fails sanity check
+See \`config.log' for more details." >&5
+echo "$as_me: error: C preprocessor \"$CPP\" fails sanity check
+See \`config.log' for more details." >&2;}
+ { (exit 1); exit 1; }; }
+fi
+
+ac_ext=c
+ac_cpp='$CPP $CPPFLAGS'
+ac_compile='$CC -c $CFLAGS $CPPFLAGS conftest.$ac_ext >&5'
+ac_link='$CC -o conftest$ac_exeext $CFLAGS $CPPFLAGS $LDFLAGS conftest.$ac_ext $LIBS >&5'
+ac_compiler_gnu=$ac_cv_c_compiler_gnu
+
+
+echo "$as_me:$LINENO: checking for egrep" >&5
+echo $ECHO_N "checking for egrep... $ECHO_C" >&6
+if test "${ac_cv_prog_egrep+set}" = set; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+else
+ if echo a | (grep -E '(a|b)') >/dev/null 2>&1
+ then ac_cv_prog_egrep='grep -E'
+ else ac_cv_prog_egrep='egrep'
+ fi
+fi
+echo "$as_me:$LINENO: result: $ac_cv_prog_egrep" >&5
+echo "${ECHO_T}$ac_cv_prog_egrep" >&6
+ EGREP=$ac_cv_prog_egrep
+
+
+echo "$as_me:$LINENO: checking for ANSI C header files" >&5
+echo $ECHO_N "checking for ANSI C header files... $ECHO_C" >&6
+if test "${ac_cv_header_stdc+set}" = set; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+else
+ cat >conftest.$ac_ext <<_ACEOF
+#line $LINENO "configure"
+/* confdefs.h. */
+_ACEOF
+cat confdefs.h >>conftest.$ac_ext
+cat >>conftest.$ac_ext <<_ACEOF
+/* end confdefs.h. */
+#include <stdlib.h>
+#include <stdarg.h>
+#include <string.h>
+#include <float.h>
+
+int
+main ()
+{
+
+ ;
+ return 0;
+}
+_ACEOF
+rm -f conftest.$ac_objext
+if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5
+ (eval $ac_compile) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); } &&
+ { ac_try='test -s conftest.$ac_objext'
+ { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5
+ (eval $ac_try) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); }; }; then
+ ac_cv_header_stdc=yes
+else
+ echo "$as_me: failed program was:" >&5
+sed 's/^/| /' conftest.$ac_ext >&5
+
+ac_cv_header_stdc=no
+fi
+rm -f conftest.$ac_objext conftest.$ac_ext
+
+if test $ac_cv_header_stdc = yes; then
+ # SunOS 4.x string.h does not declare mem*, contrary to ANSI.
+ cat >conftest.$ac_ext <<_ACEOF
+#line $LINENO "configure"
+/* confdefs.h. */
+_ACEOF
+cat confdefs.h >>conftest.$ac_ext
+cat >>conftest.$ac_ext <<_ACEOF
+/* end confdefs.h. */
+#include <string.h>
+
+_ACEOF
+if (eval "$ac_cpp conftest.$ac_ext") 2>&5 |
+ $EGREP "memchr" >/dev/null 2>&1; then
+ :
+else
+ ac_cv_header_stdc=no
+fi
+rm -f conftest*
+
+fi
+
+if test $ac_cv_header_stdc = yes; then
+ # ISC 2.0.2 stdlib.h does not declare free, contrary to ANSI.
+ cat >conftest.$ac_ext <<_ACEOF
+#line $LINENO "configure"
+/* confdefs.h. */
+_ACEOF
+cat confdefs.h >>conftest.$ac_ext
+cat >>conftest.$ac_ext <<_ACEOF
+/* end confdefs.h. */
+#include <stdlib.h>
+
+_ACEOF
+if (eval "$ac_cpp conftest.$ac_ext") 2>&5 |
+ $EGREP "free" >/dev/null 2>&1; then
+ :
+else
+ ac_cv_header_stdc=no
+fi
+rm -f conftest*
+
+fi
+
+if test $ac_cv_header_stdc = yes; then
+ # /bin/cc in Irix-4.0.5 gets non-ANSI ctype macros unless using -ansi.
+ if test "$cross_compiling" = yes; then
+ :
+else
+ cat >conftest.$ac_ext <<_ACEOF
+#line $LINENO "configure"
+/* confdefs.h. */
+_ACEOF
+cat confdefs.h >>conftest.$ac_ext
+cat >>conftest.$ac_ext <<_ACEOF
+/* end confdefs.h. */
+#include <ctype.h>
+#if ((' ' & 0x0FF) == 0x020)
+# define ISLOWER(c) ('a' <= (c) && (c) <= 'z')
+# define TOUPPER(c) (ISLOWER(c) ? 'A' + ((c) - 'a') : (c))
+#else
+# define ISLOWER(c) \
+ (('a' <= (c) && (c) <= 'i') \
+ || ('j' <= (c) && (c) <= 'r') \
+ || ('s' <= (c) && (c) <= 'z'))
+# define TOUPPER(c) (ISLOWER(c) ? ((c) | 0x40) : (c))
+#endif
+
+#define XOR(e, f) (((e) && !(f)) || (!(e) && (f)))
+int
+main ()
+{
+ int i;
+ for (i = 0; i < 256; i++)
+ if (XOR (islower (i), ISLOWER (i))
+ || toupper (i) != TOUPPER (i))
+ exit(2);
+ exit (0);
+}
+_ACEOF
+rm -f conftest$ac_exeext
+if { (eval echo "$as_me:$LINENO: \"$ac_link\"") >&5
+ (eval $ac_link) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); } && { ac_try='./conftest$ac_exeext'
+ { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5
+ (eval $ac_try) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); }; }; then
+ :
+else
+ echo "$as_me: program exited with status $ac_status" >&5
+echo "$as_me: failed program was:" >&5
+sed 's/^/| /' conftest.$ac_ext >&5
+
+( exit $ac_status )
+ac_cv_header_stdc=no
+fi
+rm -f core core.* *.core gmon.out bb.out conftest$ac_exeext conftest.$ac_objext conftest.$ac_ext
+fi
+fi
+fi
+echo "$as_me:$LINENO: result: $ac_cv_header_stdc" >&5
+echo "${ECHO_T}$ac_cv_header_stdc" >&6
+if test $ac_cv_header_stdc = yes; then
+
+cat >>confdefs.h <<\_ACEOF
+#define STDC_HEADERS 1
+_ACEOF
+
+fi
+
+# On IRIX 5.3, sys/types and inttypes.h are conflicting.
+
+
+
+
+
+
+
+
+
+for ac_header in sys/types.h sys/stat.h stdlib.h string.h memory.h strings.h \
+ inttypes.h stdint.h unistd.h
+do
+as_ac_Header=`echo "ac_cv_header_$ac_header" | $as_tr_sh`
+echo "$as_me:$LINENO: checking for $ac_header" >&5
+echo $ECHO_N "checking for $ac_header... $ECHO_C" >&6
+if eval "test \"\${$as_ac_Header+set}\" = set"; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+else
+ cat >conftest.$ac_ext <<_ACEOF
+#line $LINENO "configure"
+/* confdefs.h. */
+_ACEOF
+cat confdefs.h >>conftest.$ac_ext
+cat >>conftest.$ac_ext <<_ACEOF
+/* end confdefs.h. */
+$ac_includes_default
+
+#include <$ac_header>
+_ACEOF
+rm -f conftest.$ac_objext
+if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5
+ (eval $ac_compile) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); } &&
+ { ac_try='test -s conftest.$ac_objext'
+ { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5
+ (eval $ac_try) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); }; }; then
+ eval "$as_ac_Header=yes"
+else
+ echo "$as_me: failed program was:" >&5
+sed 's/^/| /' conftest.$ac_ext >&5
+
+eval "$as_ac_Header=no"
+fi
+rm -f conftest.$ac_objext conftest.$ac_ext
+fi
+echo "$as_me:$LINENO: result: `eval echo '${'$as_ac_Header'}'`" >&5
+echo "${ECHO_T}`eval echo '${'$as_ac_Header'}'`" >&6
+if test `eval echo '${'$as_ac_Header'}'` = yes; then
+ cat >>confdefs.h <<_ACEOF
+#define `echo "HAVE_$ac_header" | $as_tr_cpp` 1
+_ACEOF
+
+fi
+
+done
+
+
+if test "${ac_cv_header_g2_h+set}" = set; then
+ echo "$as_me:$LINENO: checking for g2.h" >&5
+echo $ECHO_N "checking for g2.h... $ECHO_C" >&6
+if test "${ac_cv_header_g2_h+set}" = set; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+fi
+echo "$as_me:$LINENO: result: $ac_cv_header_g2_h" >&5
+echo "${ECHO_T}$ac_cv_header_g2_h" >&6
+else
+ # Is the header compilable?
+echo "$as_me:$LINENO: checking g2.h usability" >&5
+echo $ECHO_N "checking g2.h usability... $ECHO_C" >&6
+cat >conftest.$ac_ext <<_ACEOF
+#line $LINENO "configure"
+/* confdefs.h. */
+_ACEOF
+cat confdefs.h >>conftest.$ac_ext
+cat >>conftest.$ac_ext <<_ACEOF
+/* end confdefs.h. */
+$ac_includes_default
+#include <g2.h>
+_ACEOF
+rm -f conftest.$ac_objext
+if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5
+ (eval $ac_compile) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); } &&
+ { ac_try='test -s conftest.$ac_objext'
+ { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5
+ (eval $ac_try) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); }; }; then
+ ac_header_compiler=yes
+else
+ echo "$as_me: failed program was:" >&5
+sed 's/^/| /' conftest.$ac_ext >&5
+
+ac_header_compiler=no
+fi
+rm -f conftest.$ac_objext conftest.$ac_ext
+echo "$as_me:$LINENO: result: $ac_header_compiler" >&5
+echo "${ECHO_T}$ac_header_compiler" >&6
+
+# Is the header present?
+echo "$as_me:$LINENO: checking g2.h presence" >&5
+echo $ECHO_N "checking g2.h presence... $ECHO_C" >&6
+cat >conftest.$ac_ext <<_ACEOF
+#line $LINENO "configure"
+/* confdefs.h. */
+_ACEOF
+cat confdefs.h >>conftest.$ac_ext
+cat >>conftest.$ac_ext <<_ACEOF
+/* end confdefs.h. */
+#include <g2.h>
+_ACEOF
+if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5
+ (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1
+ ac_status=$?
+ grep -v '^ *+' conftest.er1 >conftest.err
+ rm -f conftest.er1
+ cat conftest.err >&5
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); } >/dev/null; then
+ if test -s conftest.err; then
+ ac_cpp_err=$ac_c_preproc_warn_flag
+ else
+ ac_cpp_err=
+ fi
+else
+ ac_cpp_err=yes
+fi
+if test -z "$ac_cpp_err"; then
+ ac_header_preproc=yes
+else
+ echo "$as_me: failed program was:" >&5
+sed 's/^/| /' conftest.$ac_ext >&5
+
+ ac_header_preproc=no
+fi
+rm -f conftest.err conftest.$ac_ext
+echo "$as_me:$LINENO: result: $ac_header_preproc" >&5
+echo "${ECHO_T}$ac_header_preproc" >&6
+
+# So? What about this header?
+case $ac_header_compiler:$ac_header_preproc in
+ yes:no )
+ { echo "$as_me:$LINENO: WARNING: g2.h: accepted by the compiler, rejected by the preprocessor!" >&5
+echo "$as_me: WARNING: g2.h: accepted by the compiler, rejected by the preprocessor!" >&2;}
+ { echo "$as_me:$LINENO: WARNING: g2.h: proceeding with the preprocessor's result" >&5
+echo "$as_me: WARNING: g2.h: proceeding with the preprocessor's result" >&2;}
+ (
+ cat <<\_ASBOX
+## ------------------------------------ ##
+## Report this to bug-autoconf at gnu.org. ##
+## ------------------------------------ ##
+_ASBOX
+ ) |
+ sed "s/^/$as_me: WARNING: /" >&2
+ ;;
+ no:yes )
+ { echo "$as_me:$LINENO: WARNING: g2.h: present but cannot be compiled" >&5
+echo "$as_me: WARNING: g2.h: present but cannot be compiled" >&2;}
+ { echo "$as_me:$LINENO: WARNING: g2.h: check for missing prerequisite headers?" >&5
+echo "$as_me: WARNING: g2.h: check for missing prerequisite headers?" >&2;}
+ { echo "$as_me:$LINENO: WARNING: g2.h: proceeding with the preprocessor's result" >&5
+echo "$as_me: WARNING: g2.h: proceeding with the preprocessor's result" >&2;}
+ (
+ cat <<\_ASBOX
+## ------------------------------------ ##
+## Report this to bug-autoconf at gnu.org. ##
+## ------------------------------------ ##
+_ASBOX
+ ) |
+ sed "s/^/$as_me: WARNING: /" >&2
+ ;;
+esac
+echo "$as_me:$LINENO: checking for g2.h" >&5
+echo $ECHO_N "checking for g2.h... $ECHO_C" >&6
+if test "${ac_cv_header_g2_h+set}" = set; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+else
+ ac_cv_header_g2_h=$ac_header_preproc
+fi
+echo "$as_me:$LINENO: result: $ac_cv_header_g2_h" >&5
+echo "${ECHO_T}$ac_cv_header_g2_h" >&6
+
+fi
+
+
+if test "${ac_cv_header_g2_PS_h+set}" = set; then
+ echo "$as_me:$LINENO: checking for g2_PS.h" >&5
+echo $ECHO_N "checking for g2_PS.h... $ECHO_C" >&6
+if test "${ac_cv_header_g2_PS_h+set}" = set; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+fi
+echo "$as_me:$LINENO: result: $ac_cv_header_g2_PS_h" >&5
+echo "${ECHO_T}$ac_cv_header_g2_PS_h" >&6
+else
+ # Is the header compilable?
+echo "$as_me:$LINENO: checking g2_PS.h usability" >&5
+echo $ECHO_N "checking g2_PS.h usability... $ECHO_C" >&6
+cat >conftest.$ac_ext <<_ACEOF
+#line $LINENO "configure"
+/* confdefs.h. */
+_ACEOF
+cat confdefs.h >>conftest.$ac_ext
+cat >>conftest.$ac_ext <<_ACEOF
+/* end confdefs.h. */
+$ac_includes_default
+#include <g2_PS.h>
+_ACEOF
+rm -f conftest.$ac_objext
+if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5
+ (eval $ac_compile) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); } &&
+ { ac_try='test -s conftest.$ac_objext'
+ { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5
+ (eval $ac_try) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); }; }; then
+ ac_header_compiler=yes
+else
+ echo "$as_me: failed program was:" >&5
+sed 's/^/| /' conftest.$ac_ext >&5
+
+ac_header_compiler=no
+fi
+rm -f conftest.$ac_objext conftest.$ac_ext
+echo "$as_me:$LINENO: result: $ac_header_compiler" >&5
+echo "${ECHO_T}$ac_header_compiler" >&6
+
+# Is the header present?
+echo "$as_me:$LINENO: checking g2_PS.h presence" >&5
+echo $ECHO_N "checking g2_PS.h presence... $ECHO_C" >&6
+cat >conftest.$ac_ext <<_ACEOF
+#line $LINENO "configure"
+/* confdefs.h. */
+_ACEOF
+cat confdefs.h >>conftest.$ac_ext
+cat >>conftest.$ac_ext <<_ACEOF
+/* end confdefs.h. */
+#include <g2_PS.h>
+_ACEOF
+if { (eval echo "$as_me:$LINENO: \"$ac_cpp conftest.$ac_ext\"") >&5
+ (eval $ac_cpp conftest.$ac_ext) 2>conftest.er1
+ ac_status=$?
+ grep -v '^ *+' conftest.er1 >conftest.err
+ rm -f conftest.er1
+ cat conftest.err >&5
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); } >/dev/null; then
+ if test -s conftest.err; then
+ ac_cpp_err=$ac_c_preproc_warn_flag
+ else
+ ac_cpp_err=
+ fi
+else
+ ac_cpp_err=yes
+fi
+if test -z "$ac_cpp_err"; then
+ ac_header_preproc=yes
+else
+ echo "$as_me: failed program was:" >&5
+sed 's/^/| /' conftest.$ac_ext >&5
+
+ ac_header_preproc=no
+fi
+rm -f conftest.err conftest.$ac_ext
+echo "$as_me:$LINENO: result: $ac_header_preproc" >&5
+echo "${ECHO_T}$ac_header_preproc" >&6
+
+# So? What about this header?
+case $ac_header_compiler:$ac_header_preproc in
+ yes:no )
+ { echo "$as_me:$LINENO: WARNING: g2_PS.h: accepted by the compiler, rejected by the preprocessor!" >&5
+echo "$as_me: WARNING: g2_PS.h: accepted by the compiler, rejected by the preprocessor!" >&2;}
+ { echo "$as_me:$LINENO: WARNING: g2_PS.h: proceeding with the preprocessor's result" >&5
+echo "$as_me: WARNING: g2_PS.h: proceeding with the preprocessor's result" >&2;}
+ (
+ cat <<\_ASBOX
+## ------------------------------------ ##
+## Report this to bug-autoconf at gnu.org. ##
+## ------------------------------------ ##
+_ASBOX
+ ) |
+ sed "s/^/$as_me: WARNING: /" >&2
+ ;;
+ no:yes )
+ { echo "$as_me:$LINENO: WARNING: g2_PS.h: present but cannot be compiled" >&5
+echo "$as_me: WARNING: g2_PS.h: present but cannot be compiled" >&2;}
+ { echo "$as_me:$LINENO: WARNING: g2_PS.h: check for missing prerequisite headers?" >&5
+echo "$as_me: WARNING: g2_PS.h: check for missing prerequisite headers?" >&2;}
+ { echo "$as_me:$LINENO: WARNING: g2_PS.h: proceeding with the preprocessor's result" >&5
+echo "$as_me: WARNING: g2_PS.h: proceeding with the preprocessor's result" >&2;}
+ (
+ cat <<\_ASBOX
+## ------------------------------------ ##
+## Report this to bug-autoconf at gnu.org. ##
+## ------------------------------------ ##
+_ASBOX
+ ) |
+ sed "s/^/$as_me: WARNING: /" >&2
+ ;;
+esac
+echo "$as_me:$LINENO: checking for g2_PS.h" >&5
+echo $ECHO_N "checking for g2_PS.h... $ECHO_C" >&6
+if test "${ac_cv_header_g2_PS_h+set}" = set; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+else
+ ac_cv_header_g2_PS_h=$ac_header_preproc
+fi
+echo "$as_me:$LINENO: result: $ac_cv_header_g2_PS_h" >&5
+echo "${ECHO_T}$ac_cv_header_g2_PS_h" >&6
+
+fi
+
+
+
+echo "$as_me:$LINENO: checking for an ANSI C-conforming const" >&5
+echo $ECHO_N "checking for an ANSI C-conforming const... $ECHO_C" >&6
+if test "${ac_cv_c_const+set}" = set; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+else
+ cat >conftest.$ac_ext <<_ACEOF
+#line $LINENO "configure"
+/* confdefs.h. */
+_ACEOF
+cat confdefs.h >>conftest.$ac_ext
+cat >>conftest.$ac_ext <<_ACEOF
+/* end confdefs.h. */
+
+int
+main ()
+{
+/* FIXME: Include the comments suggested by Paul. */
+#ifndef __cplusplus
+ /* Ultrix mips cc rejects this. */
+ typedef int charset[2];
+ const charset x;
+ /* SunOS 4.1.1 cc rejects this. */
+ char const *const *ccp;
+ char **p;
+ /* NEC SVR4.0.2 mips cc rejects this. */
+ struct point {int x, y;};
+ static struct point const zero = {0,0};
+ /* AIX XL C 1.02.0.0 rejects this.
+ It does not let you subtract one const X* pointer from another in
+ an arm of an if-expression whose if-part is not a constant
+ expression */
+ const char *g = "string";
+ ccp = &g + (g ? g-g : 0);
+ /* HPUX 7.0 cc rejects these. */
+ ++ccp;
+ p = (char**) ccp;
+ ccp = (char const *const *) p;
+ { /* SCO 3.2v4 cc rejects this. */
+ char *t;
+ char const *s = 0 ? (char *) 0 : (char const *) 0;
+
+ *t++ = 0;
+ }
+ { /* Someone thinks the Sun supposedly-ANSI compiler will reject this. */
+ int x[] = {25, 17};
+ const int *foo = &x[0];
+ ++foo;
+ }
+ { /* Sun SC1.0 ANSI compiler rejects this -- but not the above. */
+ typedef const int *iptr;
+ iptr p = 0;
+ ++p;
+ }
+ { /* AIX XL C 1.02.0.0 rejects this saying
+ "k.c", line 2.27: 1506-025 (S) Operand must be a modifiable lvalue. */
+ struct s { int j; const int *ap[3]; };
+ struct s *b; b->j = 5;
+ }
+ { /* ULTRIX-32 V3.1 (Rev 9) vcc rejects this */
+ const int foo = 10;
+ }
+#endif
+
+ ;
+ return 0;
+}
+_ACEOF
+rm -f conftest.$ac_objext
+if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5
+ (eval $ac_compile) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); } &&
+ { ac_try='test -s conftest.$ac_objext'
+ { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5
+ (eval $ac_try) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); }; }; then
+ ac_cv_c_const=yes
+else
+ echo "$as_me: failed program was:" >&5
+sed 's/^/| /' conftest.$ac_ext >&5
+
+ac_cv_c_const=no
+fi
+rm -f conftest.$ac_objext conftest.$ac_ext
+fi
+echo "$as_me:$LINENO: result: $ac_cv_c_const" >&5
+echo "${ECHO_T}$ac_cv_c_const" >&6
+if test $ac_cv_c_const = no; then
+
+cat >>confdefs.h <<\_ACEOF
+#define const
+_ACEOF
+
+fi
+
+echo "$as_me:$LINENO: checking for inline" >&5
+echo $ECHO_N "checking for inline... $ECHO_C" >&6
+if test "${ac_cv_c_inline+set}" = set; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+else
+ ac_cv_c_inline=no
+for ac_kw in inline __inline__ __inline; do
+ cat >conftest.$ac_ext <<_ACEOF
+#line $LINENO "configure"
+/* confdefs.h. */
+_ACEOF
+cat confdefs.h >>conftest.$ac_ext
+cat >>conftest.$ac_ext <<_ACEOF
+/* end confdefs.h. */
+#ifndef __cplusplus
+typedef int foo_t;
+static $ac_kw foo_t static_foo () {return 0; }
+$ac_kw foo_t foo () {return 0; }
+#endif
+
+_ACEOF
+rm -f conftest.$ac_objext
+if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5
+ (eval $ac_compile) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); } &&
+ { ac_try='test -s conftest.$ac_objext'
+ { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5
+ (eval $ac_try) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); }; }; then
+ ac_cv_c_inline=$ac_kw; break
+else
+ echo "$as_me: failed program was:" >&5
+sed 's/^/| /' conftest.$ac_ext >&5
+
+fi
+rm -f conftest.$ac_objext conftest.$ac_ext
+done
+
+fi
+echo "$as_me:$LINENO: result: $ac_cv_c_inline" >&5
+echo "${ECHO_T}$ac_cv_c_inline" >&6
+case $ac_cv_c_inline in
+ inline | yes) ;;
+ no)
+cat >>confdefs.h <<\_ACEOF
+#define inline
+_ACEOF
+ ;;
+ *) cat >>confdefs.h <<_ACEOF
+#define inline $ac_cv_c_inline
+_ACEOF
+ ;;
+esac
+
+echo "$as_me:$LINENO: checking for size_t" >&5
+echo $ECHO_N "checking for size_t... $ECHO_C" >&6
+if test "${ac_cv_type_size_t+set}" = set; then
+ echo $ECHO_N "(cached) $ECHO_C" >&6
+else
+ cat >conftest.$ac_ext <<_ACEOF
+#line $LINENO "configure"
+/* confdefs.h. */
+_ACEOF
+cat confdefs.h >>conftest.$ac_ext
+cat >>conftest.$ac_ext <<_ACEOF
+/* end confdefs.h. */
+$ac_includes_default
+int
+main ()
+{
+if ((size_t *) 0)
+ return 0;
+if (sizeof (size_t))
+ return 0;
+ ;
+ return 0;
+}
+_ACEOF
+rm -f conftest.$ac_objext
+if { (eval echo "$as_me:$LINENO: \"$ac_compile\"") >&5
+ (eval $ac_compile) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); } &&
+ { ac_try='test -s conftest.$ac_objext'
+ { (eval echo "$as_me:$LINENO: \"$ac_try\"") >&5
+ (eval $ac_try) 2>&5
+ ac_status=$?
+ echo "$as_me:$LINENO: \$? = $ac_status" >&5
+ (exit $ac_status); }; }; then
+ ac_cv_type_size_t=yes
+else
+ echo "$as_me: failed program was:" >&5
+sed 's/^/| /' conftest.$ac_ext >&5
+
+ac_cv_type_size_t=no
+fi
+rm -f conftest.$ac_objext conftest.$ac_ext
+fi
+echo "$as_me:$LINENO: result: $ac_cv_type_size_t" >&5
+echo "${ECHO_T}$ac_cv_type_size_t" >&6
+if test $ac_cv_type_size_t = yes; then
+ :
+else
+
+cat >>confdefs.h <<_ACEOF
+#define size_t unsigned
+_ACEOF
+
+fi
+
+
+
+
+ ac_config_files="$ac_config_files Makefile src/Makefile man/Makefile"
+cat >confcache <<\_ACEOF
+# This file is a shell script that caches the results of configure
+# tests run on this system so they can be shared between configure
+# scripts and configure runs, see configure's option --config-cache.
+# It is not useful on other systems. If it contains results you don't
+# want to keep, you may remove or edit it.
+#
+# config.status only pays attention to the cache file if you give it
+# the --recheck option to rerun configure.
+#
+# `ac_cv_env_foo' variables (set or unset) will be overridden when
+# loading this file, other *unset* `ac_cv_foo' will be assigned the
+# following values.
+
+_ACEOF
+
+# The following way of writing the cache mishandles newlines in values,
+# but we know of no workaround that is simple, portable, and efficient.
+# So, don't put newlines in cache variables' values.
+# Ultrix sh set writes to stderr and can't be redirected directly,
+# and sets the high bit in the cache file unless we assign to the vars.
+{
+ (set) 2>&1 |
+ case `(ac_space=' '; set | grep ac_space) 2>&1` in
+ *ac_space=\ *)
+ # `set' does not quote correctly, so add quotes (double-quote
+ # substitution turns \\\\ into \\, and sed turns \\ into \).
+ sed -n \
+ "s/'/'\\\\''/g;
+ s/^\\([_$as_cr_alnum]*_cv_[_$as_cr_alnum]*\\)=\\(.*\\)/\\1='\\2'/p"
+ ;;
+ *)
+ # `set' quotes correctly as required by POSIX, so do not add quotes.
+ sed -n \
+ "s/^\\([_$as_cr_alnum]*_cv_[_$as_cr_alnum]*\\)=\\(.*\\)/\\1=\\2/p"
+ ;;
+ esac;
+} |
+ sed '
+ t clear
+ : clear
+ s/^\([^=]*\)=\(.*[{}].*\)$/test "${\1+set}" = set || &/
+ t end
+ /^ac_cv_env/!s/^\([^=]*\)=\(.*\)$/\1=${\1=\2}/
+ : end' >>confcache
+if diff $cache_file confcache >/dev/null 2>&1; then :; else
+ if test -w $cache_file; then
+ test "x$cache_file" != "x/dev/null" && echo "updating cache $cache_file"
+ cat confcache >$cache_file
+ else
+ echo "not updating unwritable cache $cache_file"
+ fi
+fi
+rm -f confcache
+
+test "x$prefix" = xNONE && prefix=$ac_default_prefix
+# Let make expand exec_prefix.
+test "x$exec_prefix" = xNONE && exec_prefix='${prefix}'
+
+# VPATH may cause trouble with some makes, so we remove $(srcdir),
+# ${srcdir} and @srcdir@ from VPATH if srcdir is ".", strip leading and
+# trailing colons and then remove the whole line if VPATH becomes empty
+# (actually we leave an empty line to preserve line numbers).
+if test "x$srcdir" = x.; then
+ ac_vpsub='/^[ ]*VPATH[ ]*=/{
+s/:*\$(srcdir):*/:/;
+s/:*\${srcdir}:*/:/;
+s/:*@srcdir@:*/:/;
+s/^\([^=]*=[ ]*\):*/\1/;
+s/:*$//;
+s/^[^=]*=[ ]*$//;
+}'
+fi
+
+DEFS=-DHAVE_CONFIG_H
+
+ac_libobjs=
+ac_ltlibobjs=
+for ac_i in : $LIBOBJS; do test "x$ac_i" = x: && continue
+ # 1. Remove the extension, and $U if already installed.
+ ac_i=`echo "$ac_i" |
+ sed 's/\$U\././;s/\.o$//;s/\.obj$//'`
+ # 2. Add them.
+ ac_libobjs="$ac_libobjs $ac_i\$U.$ac_objext"
+ ac_ltlibobjs="$ac_ltlibobjs $ac_i"'$U.lo'
+done
+LIBOBJS=$ac_libobjs
+
+LTLIBOBJS=$ac_ltlibobjs
+
+
+if test -z "${AMDEP_TRUE}" && test -z "${AMDEP_FALSE}"; then
+ { { echo "$as_me:$LINENO: error: conditional \"AMDEP\" was never defined.
+Usually this means the macro was only invoked conditionally." >&5
+echo "$as_me: error: conditional \"AMDEP\" was never defined.
+Usually this means the macro was only invoked conditionally." >&2;}
+ { (exit 1); exit 1; }; }
+fi
+if test -z "${am__fastdepCC_TRUE}" && test -z "${am__fastdepCC_FALSE}"; then
+ { { echo "$as_me:$LINENO: error: conditional \"am__fastdepCC\" was never defined.
+Usually this means the macro was only invoked conditionally." >&5
+echo "$as_me: error: conditional \"am__fastdepCC\" was never defined.
+Usually this means the macro was only invoked conditionally." >&2;}
+ { (exit 1); exit 1; }; }
+fi
+
+: ${CONFIG_STATUS=./config.status}
+ac_clean_files_save=$ac_clean_files
+ac_clean_files="$ac_clean_files $CONFIG_STATUS"
+{ echo "$as_me:$LINENO: creating $CONFIG_STATUS" >&5
+echo "$as_me: creating $CONFIG_STATUS" >&6;}
+cat >$CONFIG_STATUS <<_ACEOF
+#! $SHELL
+# Generated by $as_me.
+# Run this file to recreate the current configuration.
+# Compiler output produced by configure, useful for debugging
+# configure, is in config.log if it exists.
+
+debug=false
+ac_cs_recheck=false
+ac_cs_silent=false
+SHELL=\${CONFIG_SHELL-$SHELL}
+_ACEOF
+
+cat >>$CONFIG_STATUS <<\_ACEOF
+## --------------------- ##
+## M4sh Initialization. ##
+## --------------------- ##
+
+# Be Bourne compatible
+if test -n "${ZSH_VERSION+set}" && (emulate sh) >/dev/null 2>&1; then
+ emulate sh
+ NULLCMD=:
+ # Zsh 3.x and 4.x performs word splitting on ${1+"$@"}, which
+ # is contrary to our usage. Disable this feature.
+ alias -g '${1+"$@"}'='"$@"'
+elif test -n "${BASH_VERSION+set}" && (set -o posix) >/dev/null 2>&1; then
+ set -o posix
+fi
+
+# Support unset when possible.
+if (FOO=FOO; unset FOO) >/dev/null 2>&1; then
+ as_unset=unset
+else
+ as_unset=false
+fi
+
+
+# Work around bugs in pre-3.0 UWIN ksh.
+$as_unset ENV MAIL MAILPATH
+PS1='$ '
+PS2='> '
+PS4='+ '
+
+# NLS nuisances.
+for as_var in \
+ LANG LANGUAGE LC_ADDRESS LC_ALL LC_COLLATE LC_CTYPE LC_IDENTIFICATION \
+ LC_MEASUREMENT LC_MESSAGES LC_MONETARY LC_NAME LC_NUMERIC LC_PAPER \
+ LC_TELEPHONE LC_TIME
+do
+ if (set +x; test -n "`(eval $as_var=C; export $as_var) 2>&1`"); then
+ eval $as_var=C; export $as_var
+ else
+ $as_unset $as_var
+ fi
+done
+
+# Required to use basename.
+if expr a : '\(a\)' >/dev/null 2>&1; then
+ as_expr=expr
+else
+ as_expr=false
+fi
+
+if (basename /) >/dev/null 2>&1 && test "X`basename / 2>&1`" = "X/"; then
+ as_basename=basename
+else
+ as_basename=false
+fi
+
+
+# Name of the executable.
+as_me=`$as_basename "$0" ||
+$as_expr X/"$0" : '.*/\([^/][^/]*\)/*$' \| \
+ X"$0" : 'X\(//\)$' \| \
+ X"$0" : 'X\(/\)$' \| \
+ . : '\(.\)' 2>/dev/null ||
+echo X/"$0" |
+ sed '/^.*\/\([^/][^/]*\)\/*$/{ s//\1/; q; }
+ /^X\/\(\/\/\)$/{ s//\1/; q; }
+ /^X\/\(\/\).*/{ s//\1/; q; }
+ s/.*/./; q'`
+
+
+# PATH needs CR, and LINENO needs CR and PATH.
+# Avoid depending upon Character Ranges.
+as_cr_letters='abcdefghijklmnopqrstuvwxyz'
+as_cr_LETTERS='ABCDEFGHIJKLMNOPQRSTUVWXYZ'
+as_cr_Letters=$as_cr_letters$as_cr_LETTERS
+as_cr_digits='0123456789'
+as_cr_alnum=$as_cr_Letters$as_cr_digits
+
+# The user is always right.
+if test "${PATH_SEPARATOR+set}" != set; then
+ echo "#! /bin/sh" >conf$$.sh
+ echo "exit 0" >>conf$$.sh
+ chmod +x conf$$.sh
+ if (PATH="/nonexistent;."; conf$$.sh) >/dev/null 2>&1; then
+ PATH_SEPARATOR=';'
+ else
+ PATH_SEPARATOR=:
+ fi
+ rm -f conf$$.sh
+fi
+
+
+ as_lineno_1=$LINENO
+ as_lineno_2=$LINENO
+ as_lineno_3=`(expr $as_lineno_1 + 1) 2>/dev/null`
+ test "x$as_lineno_1" != "x$as_lineno_2" &&
+ test "x$as_lineno_3" = "x$as_lineno_2" || {
+ # Find who we are. Look in the path if we contain no path at all
+ # relative or not.
+ case $0 in
+ *[\\/]* ) as_myself=$0 ;;
+ *) as_save_IFS=$IFS; IFS=$PATH_SEPARATOR
+for as_dir in $PATH
+do
+ IFS=$as_save_IFS
+ test -z "$as_dir" && as_dir=.
+ test -r "$as_dir/$0" && as_myself=$as_dir/$0 && break
+done
+
+ ;;
+ esac
+ # We did not find ourselves, most probably we were run as `sh COMMAND'
+ # in which case we are not to be found in the path.
+ if test "x$as_myself" = x; then
+ as_myself=$0
+ fi
+ if test ! -f "$as_myself"; then
+ { { echo "$as_me:$LINENO: error: cannot find myself; rerun with an absolute path" >&5
+echo "$as_me: error: cannot find myself; rerun with an absolute path" >&2;}
+ { (exit 1); exit 1; }; }
+ fi
+ case $CONFIG_SHELL in
+ '')
+ as_save_IFS=$IFS; IFS=$PATH_SEPARATOR
+for as_dir in /bin$PATH_SEPARATOR/usr/bin$PATH_SEPARATOR$PATH
+do
+ IFS=$as_save_IFS
+ test -z "$as_dir" && as_dir=.
+ for as_base in sh bash ksh sh5; do
+ case $as_dir in
+ /*)
+ if ("$as_dir/$as_base" -c '
+ as_lineno_1=$LINENO
+ as_lineno_2=$LINENO
+ as_lineno_3=`(expr $as_lineno_1 + 1) 2>/dev/null`
+ test "x$as_lineno_1" != "x$as_lineno_2" &&
+ test "x$as_lineno_3" = "x$as_lineno_2" ') 2>/dev/null; then
+ $as_unset BASH_ENV || test "${BASH_ENV+set}" != set || { BASH_ENV=; export BASH_ENV; }
+ $as_unset ENV || test "${ENV+set}" != set || { ENV=; export ENV; }
+ CONFIG_SHELL=$as_dir/$as_base
+ export CONFIG_SHELL
+ exec "$CONFIG_SHELL" "$0" ${1+"$@"}
+ fi;;
+ esac
+ done
+done
+;;
+ esac
+
+ # Create $as_me.lineno as a copy of $as_myself, but with $LINENO
+ # uniformly replaced by the line number. The first 'sed' inserts a
+ # line-number line before each line; the second 'sed' does the real
+ # work. The second script uses 'N' to pair each line-number line
+ # with the numbered line, and appends trailing '-' during
+ # substitution so that $LINENO is not a special case at line end.
+ # (Raja R Harinath suggested sed '=', and Paul Eggert wrote the
+ # second 'sed' script. Blame Lee E. McMahon for sed's syntax. :-)
+ sed '=' <$as_myself |
+ sed '
+ N
+ s,$,-,
+ : loop
+ s,^\(['$as_cr_digits']*\)\(.*\)[$]LINENO\([^'$as_cr_alnum'_]\),\1\2\1\3,
+ t loop
+ s,-$,,
+ s,^['$as_cr_digits']*\n,,
+ ' >$as_me.lineno &&
+ chmod +x $as_me.lineno ||
+ { { echo "$as_me:$LINENO: error: cannot create $as_me.lineno; rerun with a POSIX shell" >&5
+echo "$as_me: error: cannot create $as_me.lineno; rerun with a POSIX shell" >&2;}
+ { (exit 1); exit 1; }; }
+
+ # Don't try to exec as it changes $[0], causing all sort of problems
+ # (the dirname of $[0] is not the place where we might find the
+ # original and so on. Autoconf is especially sensible to this).
+ . ./$as_me.lineno
+ # Exit status is that of the last command.
+ exit
+}
+
+
+case `echo "testing\c"; echo 1,2,3`,`echo -n testing; echo 1,2,3` in
+ *c*,-n*) ECHO_N= ECHO_C='
+' ECHO_T=' ' ;;
+ *c*,* ) ECHO_N=-n ECHO_C= ECHO_T= ;;
+ *) ECHO_N= ECHO_C='\c' ECHO_T= ;;
+esac
+
+if expr a : '\(a\)' >/dev/null 2>&1; then
+ as_expr=expr
+else
+ as_expr=false
+fi
+
+rm -f conf$$ conf$$.exe conf$$.file
+echo >conf$$.file
+if ln -s conf$$.file conf$$ 2>/dev/null; then
+ # We could just check for DJGPP; but this test a) works b) is more generic
+ # and c) will remain valid once DJGPP supports symlinks (DJGPP 2.04).
+ if test -f conf$$.exe; then
+ # Don't use ln at all; we don't have any links
+ as_ln_s='cp -p'
+ else
+ as_ln_s='ln -s'
+ fi
+elif ln conf$$.file conf$$ 2>/dev/null; then
+ as_ln_s=ln
+else
+ as_ln_s='cp -p'
+fi
+rm -f conf$$ conf$$.exe conf$$.file
+
+if mkdir -p . 2>/dev/null; then
+ as_mkdir_p=:
+else
+ as_mkdir_p=false
+fi
+
+as_executable_p="test -f"
+
+# Sed expression to map a string onto a valid CPP name.
+as_tr_cpp="sed y%*$as_cr_letters%P$as_cr_LETTERS%;s%[^_$as_cr_alnum]%_%g"
+
+# Sed expression to map a string onto a valid variable name.
+as_tr_sh="sed y%*+%pp%;s%[^_$as_cr_alnum]%_%g"
+
+
+# IFS
+# We need space, tab and new line, in precisely that order.
+as_nl='
+'
+IFS=" $as_nl"
+
+# CDPATH.
+$as_unset CDPATH
+
+exec 6>&1
+
+# Open the log real soon, to keep \$[0] and so on meaningful, and to
+# report actual input values of CONFIG_FILES etc. instead of their
+# values after options handling. Logging --version etc. is OK.
+exec 5>>config.log
+{
+ echo
+ sed 'h;s/./-/g;s/^.../## /;s/...$/ ##/;p;x;p;x' <<_ASBOX
+## Running $as_me. ##
+_ASBOX
+} >&5
+cat >&5 <<_CSEOF
+
+This file was extended by RNAhybrid $as_me 1.0, which was
+generated by GNU Autoconf 2.57. Invocation command line was
+
+ CONFIG_FILES = $CONFIG_FILES
+ CONFIG_HEADERS = $CONFIG_HEADERS
+ CONFIG_LINKS = $CONFIG_LINKS
+ CONFIG_COMMANDS = $CONFIG_COMMANDS
+ $ $0 $@
+
+_CSEOF
+echo "on `(hostname || uname -n) 2>/dev/null | sed 1q`" >&5
+echo >&5
+_ACEOF
+
+# Files that config.status was made for.
+if test -n "$ac_config_files"; then
+ echo "config_files=\"$ac_config_files\"" >>$CONFIG_STATUS
+fi
+
+if test -n "$ac_config_headers"; then
+ echo "config_headers=\"$ac_config_headers\"" >>$CONFIG_STATUS
+fi
+
+if test -n "$ac_config_links"; then
+ echo "config_links=\"$ac_config_links\"" >>$CONFIG_STATUS
+fi
+
+if test -n "$ac_config_commands"; then
+ echo "config_commands=\"$ac_config_commands\"" >>$CONFIG_STATUS
+fi
+
+cat >>$CONFIG_STATUS <<\_ACEOF
+
+ac_cs_usage="\
+\`$as_me' instantiates files from templates according to the
+current configuration.
+
+Usage: $0 [OPTIONS] [FILE]...
+
+ -h, --help print this help, then exit
+ -V, --version print version number, then exit
+ -q, --quiet do not print progress messages
+ -d, --debug don't remove temporary files
+ --recheck update $as_me by reconfiguring in the same conditions
+ --file=FILE[:TEMPLATE]
+ instantiate the configuration file FILE
+ --header=FILE[:TEMPLATE]
+ instantiate the configuration header FILE
+
+Configuration files:
+$config_files
+
+Configuration headers:
+$config_headers
+
+Configuration commands:
+$config_commands
+
+Report bugs to <bug-autoconf at gnu.org>."
+_ACEOF
+
+cat >>$CONFIG_STATUS <<_ACEOF
+ac_cs_version="\\
+RNAhybrid config.status 1.0
+configured by $0, generated by GNU Autoconf 2.57,
+ with options \\"`echo "$ac_configure_args" | sed 's/[\\""\`\$]/\\\\&/g'`\\"
+
+Copyright 1992, 1993, 1994, 1995, 1996, 1998, 1999, 2000, 2001
+Free Software Foundation, Inc.
+This config.status script is free software; the Free Software Foundation
+gives unlimited permission to copy, distribute and modify it."
+srcdir=$srcdir
+INSTALL="$INSTALL"
+_ACEOF
+
+cat >>$CONFIG_STATUS <<\_ACEOF
+# If no file are specified by the user, then we need to provide default
+# value. By we need to know if files were specified by the user.
+ac_need_defaults=:
+while test $# != 0
+do
+ case $1 in
+ --*=*)
+ ac_option=`expr "x$1" : 'x\([^=]*\)='`
+ ac_optarg=`expr "x$1" : 'x[^=]*=\(.*\)'`
+ ac_shift=:
+ ;;
+ -*)
+ ac_option=$1
+ ac_optarg=$2
+ ac_shift=shift
+ ;;
+ *) # This is not an option, so the user has probably given explicit
+ # arguments.
+ ac_option=$1
+ ac_need_defaults=false;;
+ esac
+
+ case $ac_option in
+ # Handling of the options.
+_ACEOF
+cat >>$CONFIG_STATUS <<\_ACEOF
+ -recheck | --recheck | --rechec | --reche | --rech | --rec | --re | --r)
+ ac_cs_recheck=: ;;
+ --version | --vers* | -V )
+ echo "$ac_cs_version"; exit 0 ;;
+ --he | --h)
+ # Conflict between --help and --header
+ { { echo "$as_me:$LINENO: error: ambiguous option: $1
+Try \`$0 --help' for more information." >&5
+echo "$as_me: error: ambiguous option: $1
+Try \`$0 --help' for more information." >&2;}
+ { (exit 1); exit 1; }; };;
+ --help | --hel | -h )
+ echo "$ac_cs_usage"; exit 0 ;;
+ --debug | --d* | -d )
+ debug=: ;;
+ --file | --fil | --fi | --f )
+ $ac_shift
+ CONFIG_FILES="$CONFIG_FILES $ac_optarg"
+ ac_need_defaults=false;;
+ --header | --heade | --head | --hea )
+ $ac_shift
+ CONFIG_HEADERS="$CONFIG_HEADERS $ac_optarg"
+ ac_need_defaults=false;;
+ -q | -quiet | --quiet | --quie | --qui | --qu | --q \
+ | -silent | --silent | --silen | --sile | --sil | --si | --s)
+ ac_cs_silent=: ;;
+
+ # This is an error.
+ -*) { { echo "$as_me:$LINENO: error: unrecognized option: $1
+Try \`$0 --help' for more information." >&5
+echo "$as_me: error: unrecognized option: $1
+Try \`$0 --help' for more information." >&2;}
+ { (exit 1); exit 1; }; } ;;
+
+ *) ac_config_targets="$ac_config_targets $1" ;;
+
+ esac
+ shift
+done
+
+ac_configure_extra_args=
+
+if $ac_cs_silent; then
+ exec 6>/dev/null
+ ac_configure_extra_args="$ac_configure_extra_args --silent"
+fi
+
+_ACEOF
+cat >>$CONFIG_STATUS <<_ACEOF
+if \$ac_cs_recheck; then
+ echo "running $SHELL $0 " $ac_configure_args \$ac_configure_extra_args " --no-create --no-recursion" >&6
+ exec $SHELL $0 $ac_configure_args \$ac_configure_extra_args --no-create --no-recursion
+fi
+
+_ACEOF
+
+cat >>$CONFIG_STATUS <<_ACEOF
+#
+# INIT-COMMANDS section.
+#
+
+AMDEP_TRUE="$AMDEP_TRUE" ac_aux_dir="$ac_aux_dir"
+
+_ACEOF
+
+
+
+cat >>$CONFIG_STATUS <<\_ACEOF
+for ac_config_target in $ac_config_targets
+do
+ case "$ac_config_target" in
+ # Handling of arguments.
+ "Makefile" ) CONFIG_FILES="$CONFIG_FILES Makefile" ;;
+ "src/Makefile" ) CONFIG_FILES="$CONFIG_FILES src/Makefile" ;;
+ "man/Makefile" ) CONFIG_FILES="$CONFIG_FILES man/Makefile" ;;
+ "depfiles" ) CONFIG_COMMANDS="$CONFIG_COMMANDS depfiles" ;;
+ "config.h" ) CONFIG_HEADERS="$CONFIG_HEADERS config.h" ;;
+ *) { { echo "$as_me:$LINENO: error: invalid argument: $ac_config_target" >&5
+echo "$as_me: error: invalid argument: $ac_config_target" >&2;}
+ { (exit 1); exit 1; }; };;
+ esac
+done
+
+# If the user did not use the arguments to specify the items to instantiate,
+# then the envvar interface is used. Set only those that are not.
+# We use the long form for the default assignment because of an extremely
+# bizarre bug on SunOS 4.1.3.
+if $ac_need_defaults; then
+ test "${CONFIG_FILES+set}" = set || CONFIG_FILES=$config_files
+ test "${CONFIG_HEADERS+set}" = set || CONFIG_HEADERS=$config_headers
+ test "${CONFIG_COMMANDS+set}" = set || CONFIG_COMMANDS=$config_commands
+fi
+
+# Have a temporary directory for convenience. Make it in the build tree
+# simply because there is no reason to put it here, and in addition,
+# creating and moving files from /tmp can sometimes cause problems.
+# Create a temporary directory, and hook for its removal unless debugging.
+$debug ||
+{
+ trap 'exit_status=$?; rm -rf $tmp && exit $exit_status' 0
+ trap '{ (exit 1); exit 1; }' 1 2 13 15
+}
+
+# Create a (secure) tmp directory for tmp files.
+
+{
+ tmp=`(umask 077 && mktemp -d -q "./confstatXXXXXX") 2>/dev/null` &&
+ test -n "$tmp" && test -d "$tmp"
+} ||
+{
+ tmp=./confstat$$-$RANDOM
+ (umask 077 && mkdir $tmp)
+} ||
+{
+ echo "$me: cannot create a temporary directory in ." >&2
+ { (exit 1); exit 1; }
+}
+
+_ACEOF
+
+cat >>$CONFIG_STATUS <<_ACEOF
+
+#
+# CONFIG_FILES section.
+#
+
+# No need to generate the scripts if there are no CONFIG_FILES.
+# This happens for instance when ./config.status config.h
+if test -n "\$CONFIG_FILES"; then
+ # Protect against being on the right side of a sed subst in config.status.
+ sed 's/,@/@@/; s/@,/@@/; s/,;t t\$/@;t t/; /@;t t\$/s/[\\\\&,]/\\\\&/g;
+ s/@@/,@/; s/@@/@,/; s/@;t t\$/,;t t/' >\$tmp/subs.sed <<\\CEOF
+s, at SHELL@,$SHELL,;t t
+s, at PATH_SEPARATOR@,$PATH_SEPARATOR,;t t
+s, at PACKAGE_NAME@,$PACKAGE_NAME,;t t
+s, at PACKAGE_TARNAME@,$PACKAGE_TARNAME,;t t
+s, at PACKAGE_VERSION@,$PACKAGE_VERSION,;t t
+s, at PACKAGE_STRING@,$PACKAGE_STRING,;t t
+s, at PACKAGE_BUGREPORT@,$PACKAGE_BUGREPORT,;t t
+s, at exec_prefix@,$exec_prefix,;t t
+s, at prefix@,$prefix,;t t
+s, at program_transform_name@,$program_transform_name,;t t
+s, at bindir@,$bindir,;t t
+s, at sbindir@,$sbindir,;t t
+s, at libexecdir@,$libexecdir,;t t
+s, at datadir@,$datadir,;t t
+s, at sysconfdir@,$sysconfdir,;t t
+s, at sharedstatedir@,$sharedstatedir,;t t
+s, at localstatedir@,$localstatedir,;t t
+s, at libdir@,$libdir,;t t
+s, at includedir@,$includedir,;t t
+s, at oldincludedir@,$oldincludedir,;t t
+s, at infodir@,$infodir,;t t
+s, at mandir@,$mandir,;t t
+s, at build_alias@,$build_alias,;t t
+s, at host_alias@,$host_alias,;t t
+s, at target_alias@,$target_alias,;t t
+s, at DEFS@,$DEFS,;t t
+s, at ECHO_C@,$ECHO_C,;t t
+s, at ECHO_N@,$ECHO_N,;t t
+s, at ECHO_T@,$ECHO_T,;t t
+s, at LIBS@,$LIBS,;t t
+s, at INSTALL_PROGRAM@,$INSTALL_PROGRAM,;t t
+s, at INSTALL_SCRIPT@,$INSTALL_SCRIPT,;t t
+s, at INSTALL_DATA@,$INSTALL_DATA,;t t
+s, at CYGPATH_W@,$CYGPATH_W,;t t
+s, at PACKAGE@,$PACKAGE,;t t
+s, at VERSION@,$VERSION,;t t
+s, at ACLOCAL@,$ACLOCAL,;t t
+s, at AUTOCONF@,$AUTOCONF,;t t
+s, at AUTOMAKE@,$AUTOMAKE,;t t
+s, at AUTOHEADER@,$AUTOHEADER,;t t
+s, at MAKEINFO@,$MAKEINFO,;t t
+s, at AMTAR@,$AMTAR,;t t
+s, at install_sh@,$install_sh,;t t
+s, at STRIP@,$STRIP,;t t
+s, at ac_ct_STRIP@,$ac_ct_STRIP,;t t
+s, at INSTALL_STRIP_PROGRAM@,$INSTALL_STRIP_PROGRAM,;t t
+s, at AWK@,$AWK,;t t
+s, at SET_MAKE@,$SET_MAKE,;t t
+s, at am__leading_dot@,$am__leading_dot,;t t
+s, at CC@,$CC,;t t
+s, at CFLAGS@,$CFLAGS,;t t
+s, at LDFLAGS@,$LDFLAGS,;t t
+s, at CPPFLAGS@,$CPPFLAGS,;t t
+s, at ac_ct_CC@,$ac_ct_CC,;t t
+s, at EXEEXT@,$EXEEXT,;t t
+s, at OBJEXT@,$OBJEXT,;t t
+s, at DEPDIR@,$DEPDIR,;t t
+s, at am__include@,$am__include,;t t
+s, at am__quote@,$am__quote,;t t
+s, at AMDEP_TRUE@,$AMDEP_TRUE,;t t
+s, at AMDEP_FALSE@,$AMDEP_FALSE,;t t
+s, at AMDEPBACKSLASH@,$AMDEPBACKSLASH,;t t
+s, at CCDEPMODE@,$CCDEPMODE,;t t
+s, at am__fastdepCC_TRUE@,$am__fastdepCC_TRUE,;t t
+s, at am__fastdepCC_FALSE@,$am__fastdepCC_FALSE,;t t
+s, at CPP@,$CPP,;t t
+s, at EGREP@,$EGREP,;t t
+s, at LIBOBJS@,$LIBOBJS,;t t
+s, at LTLIBOBJS@,$LTLIBOBJS,;t t
+CEOF
+
+_ACEOF
+
+ cat >>$CONFIG_STATUS <<\_ACEOF
+ # Split the substitutions into bite-sized pieces for seds with
+ # small command number limits, like on Digital OSF/1 and HP-UX.
+ ac_max_sed_lines=48
+ ac_sed_frag=1 # Number of current file.
+ ac_beg=1 # First line for current file.
+ ac_end=$ac_max_sed_lines # Line after last line for current file.
+ ac_more_lines=:
+ ac_sed_cmds=
+ while $ac_more_lines; do
+ if test $ac_beg -gt 1; then
+ sed "1,${ac_beg}d; ${ac_end}q" $tmp/subs.sed >$tmp/subs.frag
+ else
+ sed "${ac_end}q" $tmp/subs.sed >$tmp/subs.frag
+ fi
+ if test ! -s $tmp/subs.frag; then
+ ac_more_lines=false
+ else
+ # The purpose of the label and of the branching condition is to
+ # speed up the sed processing (if there are no `@' at all, there
+ # is no need to browse any of the substitutions).
+ # These are the two extra sed commands mentioned above.
+ (echo ':t
+ /@[a-zA-Z_][a-zA-Z_0-9]*@/!b' && cat $tmp/subs.frag) >$tmp/subs-$ac_sed_frag.sed
+ if test -z "$ac_sed_cmds"; then
+ ac_sed_cmds="sed -f $tmp/subs-$ac_sed_frag.sed"
+ else
+ ac_sed_cmds="$ac_sed_cmds | sed -f $tmp/subs-$ac_sed_frag.sed"
+ fi
+ ac_sed_frag=`expr $ac_sed_frag + 1`
+ ac_beg=$ac_end
+ ac_end=`expr $ac_end + $ac_max_sed_lines`
+ fi
+ done
+ if test -z "$ac_sed_cmds"; then
+ ac_sed_cmds=cat
+ fi
+fi # test -n "$CONFIG_FILES"
+
+_ACEOF
+cat >>$CONFIG_STATUS <<\_ACEOF
+for ac_file in : $CONFIG_FILES; do test "x$ac_file" = x: && continue
+ # Support "outfile[:infile[:infile...]]", defaulting infile="outfile.in".
+ case $ac_file in
+ - | *:- | *:-:* ) # input from stdin
+ cat >$tmp/stdin
+ ac_file_in=`echo "$ac_file" | sed 's,[^:]*:,,'`
+ ac_file=`echo "$ac_file" | sed 's,:.*,,'` ;;
+ *:* ) ac_file_in=`echo "$ac_file" | sed 's,[^:]*:,,'`
+ ac_file=`echo "$ac_file" | sed 's,:.*,,'` ;;
+ * ) ac_file_in=$ac_file.in ;;
+ esac
+
+ # Compute @srcdir@, @top_srcdir@, and @INSTALL@ for subdirectories.
+ ac_dir=`(dirname "$ac_file") 2>/dev/null ||
+$as_expr X"$ac_file" : 'X\(.*[^/]\)//*[^/][^/]*/*$' \| \
+ X"$ac_file" : 'X\(//\)[^/]' \| \
+ X"$ac_file" : 'X\(//\)$' \| \
+ X"$ac_file" : 'X\(/\)' \| \
+ . : '\(.\)' 2>/dev/null ||
+echo X"$ac_file" |
+ sed '/^X\(.*[^/]\)\/\/*[^/][^/]*\/*$/{ s//\1/; q; }
+ /^X\(\/\/\)[^/].*/{ s//\1/; q; }
+ /^X\(\/\/\)$/{ s//\1/; q; }
+ /^X\(\/\).*/{ s//\1/; q; }
+ s/.*/./; q'`
+ { if $as_mkdir_p; then
+ mkdir -p "$ac_dir"
+ else
+ as_dir="$ac_dir"
+ as_dirs=
+ while test ! -d "$as_dir"; do
+ as_dirs="$as_dir $as_dirs"
+ as_dir=`(dirname "$as_dir") 2>/dev/null ||
+$as_expr X"$as_dir" : 'X\(.*[^/]\)//*[^/][^/]*/*$' \| \
+ X"$as_dir" : 'X\(//\)[^/]' \| \
+ X"$as_dir" : 'X\(//\)$' \| \
+ X"$as_dir" : 'X\(/\)' \| \
+ . : '\(.\)' 2>/dev/null ||
+echo X"$as_dir" |
+ sed '/^X\(.*[^/]\)\/\/*[^/][^/]*\/*$/{ s//\1/; q; }
+ /^X\(\/\/\)[^/].*/{ s//\1/; q; }
+ /^X\(\/\/\)$/{ s//\1/; q; }
+ /^X\(\/\).*/{ s//\1/; q; }
+ s/.*/./; q'`
+ done
+ test ! -n "$as_dirs" || mkdir $as_dirs
+ fi || { { echo "$as_me:$LINENO: error: cannot create directory \"$ac_dir\"" >&5
+echo "$as_me: error: cannot create directory \"$ac_dir\"" >&2;}
+ { (exit 1); exit 1; }; }; }
+
+ ac_builddir=.
+
+if test "$ac_dir" != .; then
+ ac_dir_suffix=/`echo "$ac_dir" | sed 's,^\.[\\/],,'`
+ # A "../" for each directory in $ac_dir_suffix.
+ ac_top_builddir=`echo "$ac_dir_suffix" | sed 's,/[^\\/]*,../,g'`
+else
+ ac_dir_suffix= ac_top_builddir=
+fi
+
+case $srcdir in
+ .) # No --srcdir option. We are building in place.
+ ac_srcdir=.
+ if test -z "$ac_top_builddir"; then
+ ac_top_srcdir=.
+ else
+ ac_top_srcdir=`echo $ac_top_builddir | sed 's,/$,,'`
+ fi ;;
+ [\\/]* | ?:[\\/]* ) # Absolute path.
+ ac_srcdir=$srcdir$ac_dir_suffix;
+ ac_top_srcdir=$srcdir ;;
+ *) # Relative path.
+ ac_srcdir=$ac_top_builddir$srcdir$ac_dir_suffix
+ ac_top_srcdir=$ac_top_builddir$srcdir ;;
+esac
+# Don't blindly perform a `cd "$ac_dir"/$ac_foo && pwd` since $ac_foo can be
+# absolute.
+ac_abs_builddir=`cd "$ac_dir" && cd $ac_builddir && pwd`
+ac_abs_top_builddir=`cd "$ac_dir" && cd ${ac_top_builddir}. && pwd`
+ac_abs_srcdir=`cd "$ac_dir" && cd $ac_srcdir && pwd`
+ac_abs_top_srcdir=`cd "$ac_dir" && cd $ac_top_srcdir && pwd`
+
+
+ case $INSTALL in
+ [\\/$]* | ?:[\\/]* ) ac_INSTALL=$INSTALL ;;
+ *) ac_INSTALL=$ac_top_builddir$INSTALL ;;
+ esac
+
+ if test x"$ac_file" != x-; then
+ { echo "$as_me:$LINENO: creating $ac_file" >&5
+echo "$as_me: creating $ac_file" >&6;}
+ rm -f "$ac_file"
+ fi
+ # Let's still pretend it is `configure' which instantiates (i.e., don't
+ # use $as_me), people would be surprised to read:
+ # /* config.h. Generated by config.status. */
+ if test x"$ac_file" = x-; then
+ configure_input=
+ else
+ configure_input="$ac_file. "
+ fi
+ configure_input=$configure_input"Generated from `echo $ac_file_in |
+ sed 's,.*/,,'` by configure."
+
+ # First look for the input files in the build tree, otherwise in the
+ # src tree.
+ ac_file_inputs=`IFS=:
+ for f in $ac_file_in; do
+ case $f in
+ -) echo $tmp/stdin ;;
+ [\\/$]*)
+ # Absolute (can't be DOS-style, as IFS=:)
+ test -f "$f" || { { echo "$as_me:$LINENO: error: cannot find input file: $f" >&5
+echo "$as_me: error: cannot find input file: $f" >&2;}
+ { (exit 1); exit 1; }; }
+ echo $f;;
+ *) # Relative
+ if test -f "$f"; then
+ # Build tree
+ echo $f
+ elif test -f "$srcdir/$f"; then
+ # Source tree
+ echo $srcdir/$f
+ else
+ # /dev/null tree
+ { { echo "$as_me:$LINENO: error: cannot find input file: $f" >&5
+echo "$as_me: error: cannot find input file: $f" >&2;}
+ { (exit 1); exit 1; }; }
+ fi;;
+ esac
+ done` || { (exit 1); exit 1; }
+_ACEOF
+cat >>$CONFIG_STATUS <<_ACEOF
+ sed "$ac_vpsub
+$extrasub
+_ACEOF
+cat >>$CONFIG_STATUS <<\_ACEOF
+:t
+/@[a-zA-Z_][a-zA-Z_0-9]*@/!b
+s, at configure_input@,$configure_input,;t t
+s, at srcdir@,$ac_srcdir,;t t
+s, at abs_srcdir@,$ac_abs_srcdir,;t t
+s, at top_srcdir@,$ac_top_srcdir,;t t
+s, at abs_top_srcdir@,$ac_abs_top_srcdir,;t t
+s, at builddir@,$ac_builddir,;t t
+s, at abs_builddir@,$ac_abs_builddir,;t t
+s, at top_builddir@,$ac_top_builddir,;t t
+s, at abs_top_builddir@,$ac_abs_top_builddir,;t t
+s, at INSTALL@,$ac_INSTALL,;t t
+" $ac_file_inputs | (eval "$ac_sed_cmds") >$tmp/out
+ rm -f $tmp/stdin
+ if test x"$ac_file" != x-; then
+ mv $tmp/out $ac_file
+ else
+ cat $tmp/out
+ rm -f $tmp/out
+ fi
+
+done
+_ACEOF
+cat >>$CONFIG_STATUS <<\_ACEOF
+
+#
+# CONFIG_HEADER section.
+#
+
+# These sed commands are passed to sed as "A NAME B NAME C VALUE D", where
+# NAME is the cpp macro being defined and VALUE is the value it is being given.
+#
+# ac_d sets the value in "#define NAME VALUE" lines.
+ac_dA='s,^\([ ]*\)#\([ ]*define[ ][ ]*\)'
+ac_dB='[ ].*$,\1#\2'
+ac_dC=' '
+ac_dD=',;t'
+# ac_u turns "#undef NAME" without trailing blanks into "#define NAME VALUE".
+ac_uA='s,^\([ ]*\)#\([ ]*\)undef\([ ][ ]*\)'
+ac_uB='$,\1#\2define\3'
+ac_uC=' '
+ac_uD=',;t'
+
+for ac_file in : $CONFIG_HEADERS; do test "x$ac_file" = x: && continue
+ # Support "outfile[:infile[:infile...]]", defaulting infile="outfile.in".
+ case $ac_file in
+ - | *:- | *:-:* ) # input from stdin
+ cat >$tmp/stdin
+ ac_file_in=`echo "$ac_file" | sed 's,[^:]*:,,'`
+ ac_file=`echo "$ac_file" | sed 's,:.*,,'` ;;
+ *:* ) ac_file_in=`echo "$ac_file" | sed 's,[^:]*:,,'`
+ ac_file=`echo "$ac_file" | sed 's,:.*,,'` ;;
+ * ) ac_file_in=$ac_file.in ;;
+ esac
+
+ test x"$ac_file" != x- && { echo "$as_me:$LINENO: creating $ac_file" >&5
+echo "$as_me: creating $ac_file" >&6;}
+
+ # First look for the input files in the build tree, otherwise in the
+ # src tree.
+ ac_file_inputs=`IFS=:
+ for f in $ac_file_in; do
+ case $f in
+ -) echo $tmp/stdin ;;
+ [\\/$]*)
+ # Absolute (can't be DOS-style, as IFS=:)
+ test -f "$f" || { { echo "$as_me:$LINENO: error: cannot find input file: $f" >&5
+echo "$as_me: error: cannot find input file: $f" >&2;}
+ { (exit 1); exit 1; }; }
+ echo $f;;
+ *) # Relative
+ if test -f "$f"; then
+ # Build tree
+ echo $f
+ elif test -f "$srcdir/$f"; then
+ # Source tree
+ echo $srcdir/$f
+ else
+ # /dev/null tree
+ { { echo "$as_me:$LINENO: error: cannot find input file: $f" >&5
+echo "$as_me: error: cannot find input file: $f" >&2;}
+ { (exit 1); exit 1; }; }
+ fi;;
+ esac
+ done` || { (exit 1); exit 1; }
+ # Remove the trailing spaces.
+ sed 's/[ ]*$//' $ac_file_inputs >$tmp/in
+
+_ACEOF
+
+# Transform confdefs.h into two sed scripts, `conftest.defines' and
+# `conftest.undefs', that substitutes the proper values into
+# config.h.in to produce config.h. The first handles `#define'
+# templates, and the second `#undef' templates.
+# And first: Protect against being on the right side of a sed subst in
+# config.status. Protect against being in an unquoted here document
+# in config.status.
+rm -f conftest.defines conftest.undefs
+# Using a here document instead of a string reduces the quoting nightmare.
+# Putting comments in sed scripts is not portable.
+#
+# `end' is used to avoid that the second main sed command (meant for
+# 0-ary CPP macros) applies to n-ary macro definitions.
+# See the Autoconf documentation for `clear'.
+cat >confdef2sed.sed <<\_ACEOF
+s/[\\&,]/\\&/g
+s,[\\$`],\\&,g
+t clear
+: clear
+s,^[ ]*#[ ]*define[ ][ ]*\([^ (][^ (]*\)\(([^)]*)\)[ ]*\(.*\)$,${ac_dA}\1${ac_dB}\1\2${ac_dC}\3${ac_dD},gp
+t end
+s,^[ ]*#[ ]*define[ ][ ]*\([^ ][^ ]*\)[ ]*\(.*\)$,${ac_dA}\1${ac_dB}\1${ac_dC}\2${ac_dD},gp
+: end
+_ACEOF
+# If some macros were called several times there might be several times
+# the same #defines, which is useless. Nevertheless, we may not want to
+# sort them, since we want the *last* AC-DEFINE to be honored.
+uniq confdefs.h | sed -n -f confdef2sed.sed >conftest.defines
+sed 's/ac_d/ac_u/g' conftest.defines >conftest.undefs
+rm -f confdef2sed.sed
+
+# This sed command replaces #undef with comments. This is necessary, for
+# example, in the case of _POSIX_SOURCE, which is predefined and required
+# on some systems where configure will not decide to define it.
+cat >>conftest.undefs <<\_ACEOF
+s,^[ ]*#[ ]*undef[ ][ ]*[a-zA-Z_][a-zA-Z_0-9]*,/* & */,
+_ACEOF
+
+# Break up conftest.defines because some shells have a limit on the size
+# of here documents, and old seds have small limits too (100 cmds).
+echo ' # Handle all the #define templates only if necessary.' >>$CONFIG_STATUS
+echo ' if grep "^[ ]*#[ ]*define" $tmp/in >/dev/null; then' >>$CONFIG_STATUS
+echo ' # If there are no defines, we may have an empty if/fi' >>$CONFIG_STATUS
+echo ' :' >>$CONFIG_STATUS
+rm -f conftest.tail
+while grep . conftest.defines >/dev/null
+do
+ # Write a limited-size here document to $tmp/defines.sed.
+ echo ' cat >$tmp/defines.sed <<CEOF' >>$CONFIG_STATUS
+ # Speed up: don't consider the non `#define' lines.
+ echo '/^[ ]*#[ ]*define/!b' >>$CONFIG_STATUS
+ # Work around the forget-to-reset-the-flag bug.
+ echo 't clr' >>$CONFIG_STATUS
+ echo ': clr' >>$CONFIG_STATUS
+ sed ${ac_max_here_lines}q conftest.defines >>$CONFIG_STATUS
+ echo 'CEOF
+ sed -f $tmp/defines.sed $tmp/in >$tmp/out
+ rm -f $tmp/in
+ mv $tmp/out $tmp/in
+' >>$CONFIG_STATUS
+ sed 1,${ac_max_here_lines}d conftest.defines >conftest.tail
+ rm -f conftest.defines
+ mv conftest.tail conftest.defines
+done
+rm -f conftest.defines
+echo ' fi # grep' >>$CONFIG_STATUS
+echo >>$CONFIG_STATUS
+
+# Break up conftest.undefs because some shells have a limit on the size
+# of here documents, and old seds have small limits too (100 cmds).
+echo ' # Handle all the #undef templates' >>$CONFIG_STATUS
+rm -f conftest.tail
+while grep . conftest.undefs >/dev/null
+do
+ # Write a limited-size here document to $tmp/undefs.sed.
+ echo ' cat >$tmp/undefs.sed <<CEOF' >>$CONFIG_STATUS
+ # Speed up: don't consider the non `#undef'
+ echo '/^[ ]*#[ ]*undef/!b' >>$CONFIG_STATUS
+ # Work around the forget-to-reset-the-flag bug.
+ echo 't clr' >>$CONFIG_STATUS
+ echo ': clr' >>$CONFIG_STATUS
+ sed ${ac_max_here_lines}q conftest.undefs >>$CONFIG_STATUS
+ echo 'CEOF
+ sed -f $tmp/undefs.sed $tmp/in >$tmp/out
+ rm -f $tmp/in
+ mv $tmp/out $tmp/in
+' >>$CONFIG_STATUS
+ sed 1,${ac_max_here_lines}d conftest.undefs >conftest.tail
+ rm -f conftest.undefs
+ mv conftest.tail conftest.undefs
+done
+rm -f conftest.undefs
+
+cat >>$CONFIG_STATUS <<\_ACEOF
+ # Let's still pretend it is `configure' which instantiates (i.e., don't
+ # use $as_me), people would be surprised to read:
+ # /* config.h. Generated by config.status. */
+ if test x"$ac_file" = x-; then
+ echo "/* Generated by configure. */" >$tmp/config.h
+ else
+ echo "/* $ac_file. Generated by configure. */" >$tmp/config.h
+ fi
+ cat $tmp/in >>$tmp/config.h
+ rm -f $tmp/in
+ if test x"$ac_file" != x-; then
+ if diff $ac_file $tmp/config.h >/dev/null 2>&1; then
+ { echo "$as_me:$LINENO: $ac_file is unchanged" >&5
+echo "$as_me: $ac_file is unchanged" >&6;}
+ else
+ ac_dir=`(dirname "$ac_file") 2>/dev/null ||
+$as_expr X"$ac_file" : 'X\(.*[^/]\)//*[^/][^/]*/*$' \| \
+ X"$ac_file" : 'X\(//\)[^/]' \| \
+ X"$ac_file" : 'X\(//\)$' \| \
+ X"$ac_file" : 'X\(/\)' \| \
+ . : '\(.\)' 2>/dev/null ||
+echo X"$ac_file" |
+ sed '/^X\(.*[^/]\)\/\/*[^/][^/]*\/*$/{ s//\1/; q; }
+ /^X\(\/\/\)[^/].*/{ s//\1/; q; }
+ /^X\(\/\/\)$/{ s//\1/; q; }
+ /^X\(\/\).*/{ s//\1/; q; }
+ s/.*/./; q'`
+ { if $as_mkdir_p; then
+ mkdir -p "$ac_dir"
+ else
+ as_dir="$ac_dir"
+ as_dirs=
+ while test ! -d "$as_dir"; do
+ as_dirs="$as_dir $as_dirs"
+ as_dir=`(dirname "$as_dir") 2>/dev/null ||
+$as_expr X"$as_dir" : 'X\(.*[^/]\)//*[^/][^/]*/*$' \| \
+ X"$as_dir" : 'X\(//\)[^/]' \| \
+ X"$as_dir" : 'X\(//\)$' \| \
+ X"$as_dir" : 'X\(/\)' \| \
+ . : '\(.\)' 2>/dev/null ||
+echo X"$as_dir" |
+ sed '/^X\(.*[^/]\)\/\/*[^/][^/]*\/*$/{ s//\1/; q; }
+ /^X\(\/\/\)[^/].*/{ s//\1/; q; }
+ /^X\(\/\/\)$/{ s//\1/; q; }
+ /^X\(\/\).*/{ s//\1/; q; }
+ s/.*/./; q'`
+ done
+ test ! -n "$as_dirs" || mkdir $as_dirs
+ fi || { { echo "$as_me:$LINENO: error: cannot create directory \"$ac_dir\"" >&5
+echo "$as_me: error: cannot create directory \"$ac_dir\"" >&2;}
+ { (exit 1); exit 1; }; }; }
+
+ rm -f $ac_file
+ mv $tmp/config.h $ac_file
+ fi
+ else
+ cat $tmp/config.h
+ rm -f $tmp/config.h
+ fi
+# Compute $ac_file's index in $config_headers.
+_am_stamp_count=1
+for _am_header in $config_headers :; do
+ case $_am_header in
+ $ac_file | $ac_file:* )
+ break ;;
+ * )
+ _am_stamp_count=`expr $_am_stamp_count + 1` ;;
+ esac
+done
+echo "timestamp for $ac_file" >`(dirname $ac_file) 2>/dev/null ||
+$as_expr X$ac_file : 'X\(.*[^/]\)//*[^/][^/]*/*$' \| \
+ X$ac_file : 'X\(//\)[^/]' \| \
+ X$ac_file : 'X\(//\)$' \| \
+ X$ac_file : 'X\(/\)' \| \
+ . : '\(.\)' 2>/dev/null ||
+echo X$ac_file |
+ sed '/^X\(.*[^/]\)\/\/*[^/][^/]*\/*$/{ s//\1/; q; }
+ /^X\(\/\/\)[^/].*/{ s//\1/; q; }
+ /^X\(\/\/\)$/{ s//\1/; q; }
+ /^X\(\/\).*/{ s//\1/; q; }
+ s/.*/./; q'`/stamp-h$_am_stamp_count
+done
+_ACEOF
+cat >>$CONFIG_STATUS <<\_ACEOF
+
+#
+# CONFIG_COMMANDS section.
+#
+for ac_file in : $CONFIG_COMMANDS; do test "x$ac_file" = x: && continue
+ ac_dest=`echo "$ac_file" | sed 's,:.*,,'`
+ ac_source=`echo "$ac_file" | sed 's,[^:]*:,,'`
+ ac_dir=`(dirname "$ac_dest") 2>/dev/null ||
+$as_expr X"$ac_dest" : 'X\(.*[^/]\)//*[^/][^/]*/*$' \| \
+ X"$ac_dest" : 'X\(//\)[^/]' \| \
+ X"$ac_dest" : 'X\(//\)$' \| \
+ X"$ac_dest" : 'X\(/\)' \| \
+ . : '\(.\)' 2>/dev/null ||
+echo X"$ac_dest" |
+ sed '/^X\(.*[^/]\)\/\/*[^/][^/]*\/*$/{ s//\1/; q; }
+ /^X\(\/\/\)[^/].*/{ s//\1/; q; }
+ /^X\(\/\/\)$/{ s//\1/; q; }
+ /^X\(\/\).*/{ s//\1/; q; }
+ s/.*/./; q'`
+ ac_builddir=.
+
+if test "$ac_dir" != .; then
+ ac_dir_suffix=/`echo "$ac_dir" | sed 's,^\.[\\/],,'`
+ # A "../" for each directory in $ac_dir_suffix.
+ ac_top_builddir=`echo "$ac_dir_suffix" | sed 's,/[^\\/]*,../,g'`
+else
+ ac_dir_suffix= ac_top_builddir=
+fi
+
+case $srcdir in
+ .) # No --srcdir option. We are building in place.
+ ac_srcdir=.
+ if test -z "$ac_top_builddir"; then
+ ac_top_srcdir=.
+ else
+ ac_top_srcdir=`echo $ac_top_builddir | sed 's,/$,,'`
+ fi ;;
+ [\\/]* | ?:[\\/]* ) # Absolute path.
+ ac_srcdir=$srcdir$ac_dir_suffix;
+ ac_top_srcdir=$srcdir ;;
+ *) # Relative path.
+ ac_srcdir=$ac_top_builddir$srcdir$ac_dir_suffix
+ ac_top_srcdir=$ac_top_builddir$srcdir ;;
+esac
+# Don't blindly perform a `cd "$ac_dir"/$ac_foo && pwd` since $ac_foo can be
+# absolute.
+ac_abs_builddir=`cd "$ac_dir" && cd $ac_builddir && pwd`
+ac_abs_top_builddir=`cd "$ac_dir" && cd ${ac_top_builddir}. && pwd`
+ac_abs_srcdir=`cd "$ac_dir" && cd $ac_srcdir && pwd`
+ac_abs_top_srcdir=`cd "$ac_dir" && cd $ac_top_srcdir && pwd`
+
+
+ { echo "$as_me:$LINENO: executing $ac_dest commands" >&5
+echo "$as_me: executing $ac_dest commands" >&6;}
+ case $ac_dest in
+ depfiles ) test x"$AMDEP_TRUE" != x"" || for mf in $CONFIG_FILES; do
+ # Strip MF so we end up with the name of the file.
+ mf=`echo "$mf" | sed -e 's/:.*$//'`
+ # Check whether this is an Automake generated Makefile or not.
+ # We used to match only the files named `Makefile.in', but
+ # some people rename them; so instead we look at the file content.
+ # Grep'ing the first line is not enough: some people post-process
+ # each Makefile.in and add a new line on top of each file to say so.
+ # So let's grep whole file.
+ if grep '^#.*generated by automake' $mf > /dev/null 2>&1; then
+ dirpart=`(dirname "$mf") 2>/dev/null ||
+$as_expr X"$mf" : 'X\(.*[^/]\)//*[^/][^/]*/*$' \| \
+ X"$mf" : 'X\(//\)[^/]' \| \
+ X"$mf" : 'X\(//\)$' \| \
+ X"$mf" : 'X\(/\)' \| \
+ . : '\(.\)' 2>/dev/null ||
+echo X"$mf" |
+ sed '/^X\(.*[^/]\)\/\/*[^/][^/]*\/*$/{ s//\1/; q; }
+ /^X\(\/\/\)[^/].*/{ s//\1/; q; }
+ /^X\(\/\/\)$/{ s//\1/; q; }
+ /^X\(\/\).*/{ s//\1/; q; }
+ s/.*/./; q'`
+ else
+ continue
+ fi
+ grep '^DEP_FILES *= *[^ #]' < "$mf" > /dev/null || continue
+ # Extract the definition of DEP_FILES from the Makefile without
+ # running `make'.
+ DEPDIR=`sed -n -e '/^DEPDIR = / s///p' < "$mf"`
+ test -z "$DEPDIR" && continue
+ # When using ansi2knr, U may be empty or an underscore; expand it
+ U=`sed -n -e '/^U = / s///p' < "$mf"`
+ test -d "$dirpart/$DEPDIR" || mkdir "$dirpart/$DEPDIR"
+ # We invoke sed twice because it is the simplest approach to
+ # changing $(DEPDIR) to its actual value in the expansion.
+ for file in `sed -n -e '
+ /^DEP_FILES = .*\\\\$/ {
+ s/^DEP_FILES = //
+ :loop
+ s/\\\\$//
+ p
+ n
+ /\\\\$/ b loop
+ p
+ }
+ /^DEP_FILES = / s/^DEP_FILES = //p' < "$mf" | \
+ sed -e 's/\$(DEPDIR)/'"$DEPDIR"'/g' -e 's/\$U/'"$U"'/g'`; do
+ # Make sure the directory exists.
+ test -f "$dirpart/$file" && continue
+ fdir=`(dirname "$file") 2>/dev/null ||
+$as_expr X"$file" : 'X\(.*[^/]\)//*[^/][^/]*/*$' \| \
+ X"$file" : 'X\(//\)[^/]' \| \
+ X"$file" : 'X\(//\)$' \| \
+ X"$file" : 'X\(/\)' \| \
+ . : '\(.\)' 2>/dev/null ||
+echo X"$file" |
+ sed '/^X\(.*[^/]\)\/\/*[^/][^/]*\/*$/{ s//\1/; q; }
+ /^X\(\/\/\)[^/].*/{ s//\1/; q; }
+ /^X\(\/\/\)$/{ s//\1/; q; }
+ /^X\(\/\).*/{ s//\1/; q; }
+ s/.*/./; q'`
+ { if $as_mkdir_p; then
+ mkdir -p $dirpart/$fdir
+ else
+ as_dir=$dirpart/$fdir
+ as_dirs=
+ while test ! -d "$as_dir"; do
+ as_dirs="$as_dir $as_dirs"
+ as_dir=`(dirname "$as_dir") 2>/dev/null ||
+$as_expr X"$as_dir" : 'X\(.*[^/]\)//*[^/][^/]*/*$' \| \
+ X"$as_dir" : 'X\(//\)[^/]' \| \
+ X"$as_dir" : 'X\(//\)$' \| \
+ X"$as_dir" : 'X\(/\)' \| \
+ . : '\(.\)' 2>/dev/null ||
+echo X"$as_dir" |
+ sed '/^X\(.*[^/]\)\/\/*[^/][^/]*\/*$/{ s//\1/; q; }
+ /^X\(\/\/\)[^/].*/{ s//\1/; q; }
+ /^X\(\/\/\)$/{ s//\1/; q; }
+ /^X\(\/\).*/{ s//\1/; q; }
+ s/.*/./; q'`
+ done
+ test ! -n "$as_dirs" || mkdir $as_dirs
+ fi || { { echo "$as_me:$LINENO: error: cannot create directory $dirpart/$fdir" >&5
+echo "$as_me: error: cannot create directory $dirpart/$fdir" >&2;}
+ { (exit 1); exit 1; }; }; }
+
+ # echo "creating $dirpart/$file"
+ echo '# dummy' > "$dirpart/$file"
+ done
+done
+ ;;
+ esac
+done
+_ACEOF
+
+cat >>$CONFIG_STATUS <<\_ACEOF
+
+{ (exit 0); exit 0; }
+_ACEOF
+chmod +x $CONFIG_STATUS
+ac_clean_files=$ac_clean_files_save
+
+
+# configure is writing to config.log, and then calls config.status.
+# config.status does its own redirection, appending to config.log.
+# Unfortunately, on DOS this fails, as config.log is still kept open
+# by configure, so config.status won't be able to write to it; its
+# output is simply discarded. So we exec the FD to /dev/null,
+# effectively closing config.log, so it can be properly (re)opened and
+# appended to by config.status. When coming back to configure, we
+# need to make the FD available again.
+if test "$no_create" != yes; then
+ ac_cs_success=:
+ ac_config_status_args=
+ test "$silent" = yes &&
+ ac_config_status_args="$ac_config_status_args --quiet"
+ exec 5>/dev/null
+ $SHELL $CONFIG_STATUS $ac_config_status_args || ac_cs_success=false
+ exec 5>>config.log
+ # Use ||, not &&, to avoid exiting from the if with $? = 1, which
+ # would make configure fail if this is the last instruction.
+ $ac_cs_success || { (exit 1); exit 1; }
+fi
+
+
+
Property changes on: trunk/packages/rnahybrid/branches/upstream/current/configure
___________________________________________________________________
Name: svn:executable
+
Added: trunk/packages/rnahybrid/branches/upstream/current/configure.in
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/configure.in (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/configure.in 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,36 @@
+dnl Process this file with autoconf to produce a configure script.
+AC_REVISION($Revision: 1.0 $)
+AC_INIT(RNAhybrid,1.0,marc at techfak.uni-bielefeld.de,RNAhybrid)
+AC_PREREQ(2.53)
+AM_INIT_AUTOMAKE
+
+dnl create a config.h file (Automake will add -DHAVE_CONFIG_H)
+AM_CONFIG_HEADER(config.h)
+
+dnl Checks for programs.
+dnl AC_PROG_CXX
+AC_PROG_CC
+AC_LANG(C)
+
+dnl Checks for libraries.
+AC_CHECK_LIB(m,log,,AC_MSG_ERROR(math library is missing))
+AC_CHECK_LIB(g2,g2_open_vd,,AC_MSG_WARN(libg2.a is missing. You can download it at http://g2.sourceforge.net/))
+AC_CHECK_LIB(gd,gdImageLine,,)
+
+dnl Checks for header files.
+AC_HEADER_STDC
+AC_CHECK_HEADER(g2.h,,)
+AC_CHECK_HEADER(g2_PS.h,,)
+
+dnl Checks for typedefs, structures, and compiler characteristics.
+AC_C_CONST
+AC_C_INLINE
+AC_TYPE_SIZE_T
+
+dnl AC_SUBST(CXX)
+
+dnl Checks for library functions.
+
+AC_OUTPUT(Makefile src/Makefile man/Makefile)
+
+
Added: trunk/packages/rnahybrid/branches/upstream/current/depcomp
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/depcomp (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/depcomp 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,464 @@
+#! /bin/sh
+
+# depcomp - compile a program generating dependencies as side-effects
+# Copyright 1999, 2000 Free Software Foundation, Inc.
+
+# This program is free software; you can redistribute it and/or modify
+# it under the terms of the GNU General Public License as published by
+# the Free Software Foundation; either version 2, or (at your option)
+# any later version.
+
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
+# GNU General Public License for more details.
+
+# You should have received a copy of the GNU General Public License
+# along with this program; if not, write to the Free Software
+# Foundation, Inc., 59 Temple Place - Suite 330, Boston, MA
+# 02111-1307, USA.
+
+# As a special exception to the GNU General Public License, if you
+# distribute this file as part of a program that contains a
+# configuration script generated by Autoconf, you may include it under
+# the same distribution terms that you use for the rest of that program.
+
+# Originally written by Alexandre Oliva <oliva at dcc.unicamp.br>.
+
+if test -z "$depmode" || test -z "$source" || test -z "$object"; then
+ echo "depcomp: Variables source, object and depmode must be set" 1>&2
+ exit 1
+fi
+# `libtool' can also be set to `yes' or `no'.
+
+if test -z "$depfile"; then
+ base=`echo "$object" | sed -e 's,^.*/,,' -e 's,\.\([^.]*\)$,.P\1,'`
+ dir=`echo "$object" | sed 's,/.*$,/,'`
+ if test "$dir" = "$object"; then
+ dir=
+ fi
+ # FIXME: should be _deps on DOS.
+ depfile="$dir.deps/$base"
+fi
+
+tmpdepfile=${tmpdepfile-`echo "$depfile" | sed 's/\.\([^.]*\)$/.T\1/'`}
+
+rm -f "$tmpdepfile"
+
+# Some modes work just like other modes, but use different flags. We
+# parameterize here, but still list the modes in the big case below,
+# to make depend.m4 easier to write. Note that we *cannot* use a case
+# here, because this file can only contain one case statement.
+if test "$depmode" = hp; then
+ # HP compiler uses -M and no extra arg.
+ gccflag=-M
+ depmode=gcc
+fi
+
+if test "$depmode" = dashXmstdout; then
+ # This is just like dashmstdout with a different argument.
+ dashmflag=-xM
+ depmode=dashmstdout
+fi
+
+case "$depmode" in
+gcc3)
+## gcc 3 implements dependency tracking that does exactly what
+## we want. Yay! Note: for some reason libtool 1.4 doesn't like
+## it if -MD -MP comes after the -MF stuff. Hmm.
+ "$@" -MT "$object" -MD -MP -MF "$tmpdepfile"
+ stat=$?
+ if test $stat -eq 0; then :
+ else
+ rm -f "$tmpdepfile"
+ exit $stat
+ fi
+ mv "$tmpdepfile" "$depfile"
+ ;;
+
+gcc)
+## There are various ways to get dependency output from gcc. Here's
+## why we pick this rather obscure method:
+## - Don't want to use -MD because we'd like the dependencies to end
+## up in a subdir. Having to rename by hand is ugly.
+## (We might end up doing this anyway to support other compilers.)
+## - The DEPENDENCIES_OUTPUT environment variable makes gcc act like
+## -MM, not -M (despite what the docs say).
+## - Using -M directly means running the compiler twice (even worse
+## than renaming).
+ if test -z "$gccflag"; then
+ gccflag=-MD,
+ fi
+ "$@" -Wp,"$gccflag$tmpdepfile"
+ stat=$?
+ if test $stat -eq 0; then :
+ else
+ rm -f "$tmpdepfile"
+ exit $stat
+ fi
+ rm -f "$depfile"
+ echo "$object : \\" > "$depfile"
+ alpha=ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqrstuvwxyz
+## The second -e expression handles DOS-style file names with drive letters.
+ sed -e 's/^[^:]*: / /' \
+ -e 's/^['$alpha']:\/[^:]*: / /' < "$tmpdepfile" >> "$depfile"
+## This next piece of magic avoids the `deleted header file' problem.
+## The problem is that when a header file which appears in a .P file
+## is deleted, the dependency causes make to die (because there is
+## typically no way to rebuild the header). We avoid this by adding
+## dummy dependencies for each header file. Too bad gcc doesn't do
+## this for us directly.
+ tr ' ' '
+' < "$tmpdepfile" |
+## Some versions of gcc put a space before the `:'. On the theory
+## that the space means something, we add a space to the output as
+## well.
+## Some versions of the HPUX 10.20 sed can't process this invocation
+## correctly. Breaking it into two sed invocations is a workaround.
+ sed -e 's/^\\$//' -e '/^$/d' -e '/:$/d' | sed -e 's/$/ :/' >> "$depfile"
+ rm -f "$tmpdepfile"
+ ;;
+
+hp)
+ # This case exists only to let depend.m4 do its work. It works by
+ # looking at the text of this script. This case will never be run,
+ # since it is checked for above.
+ exit 1
+ ;;
+
+sgi)
+ if test "$libtool" = yes; then
+ "$@" "-Wp,-MDupdate,$tmpdepfile"
+ else
+ "$@" -MDupdate "$tmpdepfile"
+ fi
+ stat=$?
+ if test $stat -eq 0; then :
+ else
+ rm -f "$tmpdepfile"
+ exit $stat
+ fi
+ rm -f "$depfile"
+
+ if test -f "$tmpdepfile"; then # yes, the sourcefile depend on other files
+ echo "$object : \\" > "$depfile"
+
+ # Clip off the initial element (the dependent). Don't try to be
+ # clever and replace this with sed code, as IRIX sed won't handle
+ # lines with more than a fixed number of characters (4096 in
+ # IRIX 6.2 sed, 8192 in IRIX 6.5). We also remove comment lines;
+ # the IRIX cc adds comments like `#:fec' to the end of the
+ # dependency line.
+ tr ' ' '
+' < "$tmpdepfile" \
+ | sed -e 's/^.*\.o://' -e 's/#.*$//' -e '/^$/ d' | \
+ tr '
+' ' ' >> $depfile
+ echo >> $depfile
+
+ # The second pass generates a dummy entry for each header file.
+ tr ' ' '
+' < "$tmpdepfile" \
+ | sed -e 's/^.*\.o://' -e 's/#.*$//' -e '/^$/ d' -e 's/$/:/' \
+ >> $depfile
+ else
+ # The sourcefile does not contain any dependencies, so just
+ # store a dummy comment line, to avoid errors with the Makefile
+ # "include basename.Plo" scheme.
+ echo "#dummy" > "$depfile"
+ fi
+ rm -f "$tmpdepfile"
+ ;;
+
+aix)
+ # The C for AIX Compiler uses -M and outputs the dependencies
+ # in a .u file. This file always lives in the current directory.
+ # Also, the AIX compiler puts `$object:' at the start of each line;
+ # $object doesn't have directory information.
+ stripped=`echo "$object" | sed -e 's,^.*/,,' -e 's/\(.*\)\..*$/\1/'`
+ tmpdepfile="$stripped.u"
+ outname="$stripped.o"
+ if test "$libtool" = yes; then
+ "$@" -Wc,-M
+ else
+ "$@" -M
+ fi
+
+ stat=$?
+ if test $stat -eq 0; then :
+ else
+ rm -f "$tmpdepfile"
+ exit $stat
+ fi
+
+ if test -f "$tmpdepfile"; then
+ # Each line is of the form `foo.o: dependent.h'.
+ # Do two passes, one to just change these to
+ # `$object: dependent.h' and one to simply `dependent.h:'.
+ sed -e "s,^$outname:,$object :," < "$tmpdepfile" > "$depfile"
+ sed -e "s,^$outname: \(.*\)$,\1:," < "$tmpdepfile" >> "$depfile"
+ else
+ # The sourcefile does not contain any dependencies, so just
+ # store a dummy comment line, to avoid errors with the Makefile
+ # "include basename.Plo" scheme.
+ echo "#dummy" > "$depfile"
+ fi
+ rm -f "$tmpdepfile"
+ ;;
+
+icc)
+ # Must come before tru64.
+
+ # Intel's C compiler understands `-MD -MF file'. However
+ # icc -MD -MF foo.d -c -o sub/foo.o sub/foo.c
+ # will fill foo.d with something like
+ # foo.o: sub/foo.c
+ # foo.o: sub/foo.h
+ # which is wrong. We want:
+ # sub/foo.o: sub/foo.c
+ # sub/foo.o: sub/foo.h
+ # sub/foo.c:
+ # sub/foo.h:
+
+ "$@" -MD -MF "$tmpdepfile"
+ stat=$?
+ if test $stat -eq 0; then :
+ else
+ rm -f "$tmpdepfile"
+ exit $stat
+ fi
+ rm -f "$depfile"
+ # Each line is of the form `foo.o: dependent.h'.
+ # Do two passes, one to just change these to
+ # `$object: dependent.h' and one to simply `dependent.h:'.
+ sed -e "s,^[^:]*:,$object :," < "$tmpdepfile" > "$depfile"
+ sed -e "s,^[^:]*: \(.*\)$,\1:," < "$tmpdepfile" >> "$depfile"
+ rm -f "$tmpdepfile"
+ ;;
+
+tru64)
+ # The Tru64 compiler uses -MD to generate dependencies as a side
+ # effect. `cc -MD -o foo.o ...' puts the dependencies into `foo.o.d'.
+ # At least on Alpha/Redhat 6.1, Compaq CCC V6.2-504 seems to put
+ # dependencies in `foo.d' instead, so we check for that too.
+ # Subdirectories are respected.
+ dir=`echo "$object" | sed -e 's|/[^/]*$|/|'`
+ test "x$dir" = "x$object" && dir=
+ base=`echo "$object" | sed -e 's|^.*/||' -e 's/\.o$//' -e 's/\.lo$//'`
+
+ if test "$libtool" = yes; then
+ tmpdepfile1="$dir.libs/$base.lo.d"
+ tmpdepfile2="$dir.libs/$base.d"
+ "$@" -Wc,-MD
+ else
+ tmpdepfile1="$dir$base.o.d"
+ tmpdepfile2="$dir$base.d"
+ "$@" -MD
+ fi
+
+ stat=$?
+ if test $stat -eq 0; then :
+ else
+ rm -f "$tmpdepfile1" "$tmpdepfile2"
+ exit $stat
+ fi
+
+ if test -f "$tmpdepfile1"; then
+ tmpdepfile="$tmpdepfile1"
+ else
+ tmpdepfile="$tmpdepfile2"
+ fi
+ if test -f "$tmpdepfile"; then
+ sed -e "s,^.*\.[a-z]*:,$object:," < "$tmpdepfile" > "$depfile"
+ # That's a space and a tab in the [].
+ sed -e 's,^.*\.[a-z]*:[ ]*,,' -e 's,$,:,' < "$tmpdepfile" >> "$depfile"
+ else
+ echo "#dummy" > "$depfile"
+ fi
+ rm -f "$tmpdepfile"
+ ;;
+
+#nosideeffect)
+ # This comment above is used by automake to tell side-effect
+ # dependency tracking mechanisms from slower ones.
+
+dashmstdout)
+ # Important note: in order to support this mode, a compiler *must*
+ # always write the proprocessed file to stdout, regardless of -o.
+ "$@" || exit $?
+
+ # Remove the call to Libtool.
+ if test "$libtool" = yes; then
+ while test $1 != '--mode=compile'; do
+ shift
+ done
+ shift
+ fi
+
+ # Remove `-o $object'.
+ IFS=" "
+ for arg
+ do
+ case $arg in
+ -o)
+ shift
+ ;;
+ $object)
+ shift
+ ;;
+ *)
+ set fnord "$@" "$arg"
+ shift # fnord
+ shift # $arg
+ ;;
+ esac
+ done
+
+ test -z "$dashmflag" && dashmflag=-M
+ # Require at least two characters before searching for `:'
+ # in the target name. This is to cope with DOS-style filenames:
+ # a dependency such as `c:/foo/bar' could be seen as target `c' otherwise.
+ "$@" $dashmflag |
+ sed 's:^[ ]*[^: ][^:][^:]*\:[ ]*:'"$object"'\: :' > "$tmpdepfile"
+ rm -f "$depfile"
+ cat < "$tmpdepfile" > "$depfile"
+ tr ' ' '
+' < "$tmpdepfile" | \
+## Some versions of the HPUX 10.20 sed can't process this invocation
+## correctly. Breaking it into two sed invocations is a workaround.
+ sed -e 's/^\\$//' -e '/^$/d' -e '/:$/d' | sed -e 's/$/ :/' >> "$depfile"
+ rm -f "$tmpdepfile"
+ ;;
+
+dashXmstdout)
+ # This case only exists to satisfy depend.m4. It is never actually
+ # run, as this mode is specially recognized in the preamble.
+ exit 1
+ ;;
+
+makedepend)
+ "$@" || exit $?
+ # Remove any Libtool call
+ if test "$libtool" = yes; then
+ while test $1 != '--mode=compile'; do
+ shift
+ done
+ shift
+ fi
+ # X makedepend
+ shift
+ cleared=no
+ for arg in "$@"; do
+ case $cleared in
+ no)
+ set ""; shift
+ cleared=yes ;;
+ esac
+ case "$arg" in
+ -D*|-I*)
+ set fnord "$@" "$arg"; shift ;;
+ # Strip any option that makedepend may not understand. Remove
+ # the object too, otherwise makedepend will parse it as a source file.
+ -*|$object)
+ ;;
+ *)
+ set fnord "$@" "$arg"; shift ;;
+ esac
+ done
+ obj_suffix="`echo $object | sed 's/^.*\././'`"
+ touch "$tmpdepfile"
+ ${MAKEDEPEND-makedepend} -o"$obj_suffix" -f"$tmpdepfile" "$@"
+ rm -f "$depfile"
+ cat < "$tmpdepfile" > "$depfile"
+ sed '1,2d' "$tmpdepfile" | tr ' ' '
+' | \
+## Some versions of the HPUX 10.20 sed can't process this invocation
+## correctly. Breaking it into two sed invocations is a workaround.
+ sed -e 's/^\\$//' -e '/^$/d' -e '/:$/d' | sed -e 's/$/ :/' >> "$depfile"
+ rm -f "$tmpdepfile" "$tmpdepfile".bak
+ ;;
+
+cpp)
+ # Important note: in order to support this mode, a compiler *must*
+ # always write the proprocessed file to stdout.
+ "$@" || exit $?
+
+ # Remove the call to Libtool.
+ if test "$libtool" = yes; then
+ while test $1 != '--mode=compile'; do
+ shift
+ done
+ shift
+ fi
+
+ # Remove `-o $object'.
+ IFS=" "
+ for arg
+ do
+ case $arg in
+ -o)
+ shift
+ ;;
+ $object)
+ shift
+ ;;
+ *)
+ set fnord "$@" "$arg"
+ shift # fnord
+ shift # $arg
+ ;;
+ esac
+ done
+
+ "$@" -E |
+ sed -n '/^# [0-9][0-9]* "\([^"]*\)".*/ s:: \1 \\:p' |
+ sed '$ s: \\$::' > "$tmpdepfile"
+ rm -f "$depfile"
+ echo "$object : \\" > "$depfile"
+ cat < "$tmpdepfile" >> "$depfile"
+ sed < "$tmpdepfile" '/^$/d;s/^ //;s/ \\$//;s/$/ :/' >> "$depfile"
+ rm -f "$tmpdepfile"
+ ;;
+
+msvisualcpp)
+ # Important note: in order to support this mode, a compiler *must*
+ # always write the proprocessed file to stdout, regardless of -o,
+ # because we must use -o when running libtool.
+ "$@" || exit $?
+ IFS=" "
+ for arg
+ do
+ case "$arg" in
+ "-Gm"|"/Gm"|"-Gi"|"/Gi"|"-ZI"|"/ZI")
+ set fnord "$@"
+ shift
+ shift
+ ;;
+ *)
+ set fnord "$@" "$arg"
+ shift
+ shift
+ ;;
+ esac
+ done
+ "$@" -E |
+ sed -n '/^#line [0-9][0-9]* "\([^"]*\)"/ s::echo "`cygpath -u \\"\1\\"`":p' | sort | uniq > "$tmpdepfile"
+ rm -f "$depfile"
+ echo "$object : \\" > "$depfile"
+ . "$tmpdepfile" | sed 's% %\\ %g' | sed -n '/^\(.*\)$/ s:: \1 \\:p' >> "$depfile"
+ echo " " >> "$depfile"
+ . "$tmpdepfile" | sed 's% %\\ %g' | sed -n '/^\(.*\)$/ s::\1\::p' >> "$depfile"
+ rm -f "$tmpdepfile"
+ ;;
+
+none)
+ exec "$@"
+ ;;
+
+*)
+ echo "Unknown depmode $depmode" 1>&2
+ exit 1
+ ;;
+esac
+
+exit 0
Property changes on: trunk/packages/rnahybrid/branches/upstream/current/depcomp
___________________________________________________________________
Name: svn:executable
+
Added: trunk/packages/rnahybrid/branches/upstream/current/examples/3UTR_fly.freq
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/examples/3UTR_fly.freq (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/examples/3UTR_fly.freq 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,17 @@
+# dinucleotide frequencies from D. melanogaster 3'UTRs
+AA: 0.108608
+AC: 0.0547065
+AG: 0.0544599
+AT: 0.0872723
+CA: 0.0680076
+CC: 0.0442483
+CG: 0.0391952
+CT: 0.0523133
+GA: 0.0551463
+GC: 0.0514601
+GG: 0.0408221
+GT: 0.0517436
+TA: 0.0736475
+TC: 0.0534347
+TG: 0.0646163
+TT: 0.100022
Added: trunk/packages/rnahybrid/branches/upstream/current/examples/3UTR_human.freq
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/examples/3UTR_human.freq (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/examples/3UTR_human.freq 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,17 @@
+# dinucleotide frequencies from H. sapiens 3'UTRs
+AA: 0.0863875
+AC: 0.0486841
+AG: 0.0698675
+AT: 0.0687696
+CA: 0.0700628
+CC: 0.0617567
+CG: 0.0130357
+CT: 0.0729138
+GA: 0.0582891
+GC: 0.0477981
+GG: 0.0600536
+GT: 0.0525618
+TA: 0.0588781
+TC: 0.0595386
+TG: 0.0757252
+TT: 0.0956777
Added: trunk/packages/rnahybrid/branches/upstream/current/examples/3UTR_worm.freq
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/examples/3UTR_worm.freq (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/examples/3UTR_worm.freq 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,17 @@
+# dinucleotide frequencies from C. elegans 3'UTRs
+AA: 0.129275
+AC: 0.0478286
+AG: 0.0465314
+AT: 0.0924212
+CA: 0.0619208
+CC: 0.0341448
+CG: 0.0289974
+CT: 0.0525641
+GA: 0.0575875
+GC: 0.0311351
+GG: 0.029876
+GT: 0.0489973
+TA: 0.0672161
+TC: 0.064592
+TG: 0.0621619
+TT: 0.144751
Added: trunk/packages/rnahybrid/branches/upstream/current/examples/cbr-hbl-1.fasta
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/examples/cbr-hbl-1.fasta (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/examples/cbr-hbl-1.fasta 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,20 @@
+>ENSCBRT00000006770.1|ENSCBRG00000005546.1 assembly=CBR25|chr=cb25.fpc3857|strand=forward|downstream UTR
+TGAAGACTTCTCCCTTCATAGTCTTACCCTCATCTAGTCGACGAAACTTCCATTTGGGAATAGACTCGTTTTGTAGCTGG
+TTTTTCTTTTCCTAATATTTTAACTTATCAATGTTCGGGCGTTTTGTTATTTGTTTCCTTTTTTAATCTTGGCCATGTTC
+TTGCAATTGTACCTCAAACCATCCATTTCCATGGAATCTCAAAACCACTAGTTATCACTATATACTTTTTCTGTTTATCA
+TCCCTACCTCAAAACATATTCCCGTACTTGTTTCAATGACGCCAAAACGAAAATACCTAAAAGAGCCTTACTCTCTGTAC
+CCCCAATCTATTAAACGTGTCACTCTTAGAAGCAATTGTATACTGTTTGCCAAAGTACATGTAGTACCCCTTCTCCTCCA
+GAATACTTGTTTCTGTTACTATGTACCTTCTCAATATTTCGGGATATGGAAATTTTTCTTTGCGTGCTCCAAAAAAACCT
+TCAAATGATTTCATTCTCATTTTTTCTCAATTTCTAAGGCCCCTTCTCCACTAATAAGCTTTATTCTCTTTTGCATGTCT
+TTCAAACAACTTATTTATTTTCTATTCACCCAATTTTTTAATATGTGCATGATTCTTCTTTCTTGTTATAGCATTTTGTG
+TATTTTCCCCTTAATTATAGCCCCCTACAACCGTCCCCCTACCTCTCTCCCCAAAAATCATACGAACTCAGATTGTATTG
+CAGTTTTAACCGTTTCGAACTAGAATTCATGCCAATGATTCGTTTTTCATCTAGTTTGTCATTACTTTTTTTCATAACCG
+AAGTGACTTTTTCCCAAACCCGCTTACAACTTTTCTACCCCATCAAGCAATTTAATAATAACCGTTTTTTTTTGTTCATG
+CTACCTCAATTTGCTTATGTACCTCTTTCAAAAACTCCCATGTCCTCCCAAAAATTCTGATTTCAGTCTCCCCCTTACCT
+TCATACATCCCAAGCCTTTTGCCATACATTCTCCGTTTCAACCTAATTGCGTGCTTATTATTCATCCTTTGTATAGCCTT
+TTCAGCTTCATCAAAATTTATTGGCCCACCTCATCTCCCAGAACTCATCTCAGGAATTTACTATGCTCCATTTTCAGTAA
+AAACCTCCTCCTCTCTATGAACTACTTGTCTCTTGATTACTGTTATCCAATATTATGTACCTCATTGAATTTGCCATCCC
+CAATCCTTTTTTCTTTACCTCAAACTCATTTTTTCTCTCCATACTGGCCTATGACTGTATAATGCGTTCTACCTCCCCAA
+CTGTCCCCAATTCTAGTTATGTACCGTTTTTCTACCTCAAAAAATTAAACCCCATTATACAACCGTTCCACCTCAAACTC
+CCTCCCTTTTAGTCATGTACAATTTCTCTATCTCAAGTCGTATTCGGCTTCCACTATGAAAAATCCAATCCAATAAAAAT
+CATCATTAA
Added: trunk/packages/rnahybrid/branches/upstream/current/examples/cel-hbl-1.fasta
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/examples/cel-hbl-1.fasta (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/examples/cel-hbl-1.fasta 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,20 @@
+>F13D11.2.1|F13D11.2.1 assembly=CEL116|chr=X|strand=forward|downstream UTR
+TGAGGACGTCCTCGTTAAGGAAACACTTCCCATAGCCCCTTACCCTCGTCTAGTGACCCATTCTGAAATCGGCAGATAGA
+CTTTCATGTAGCTGGTTTAAGTTTTCTCTTCATTTTCTTTAACTTATCAATGTTCGGGCGTTACCACTTTTCTAATCATG
+GCCAGTTTCTTGCACGTACACCTCAACCGTCCATTTCCATGAAATCTCATACTTGTTACTGTTTTCTTTTACCTCTGATG
+TCACATTTTCTCTCTGTCTCACTTTCTACCTCCAAACATATTTTACTACTTGTATTGAATGCCAAAAAATACCATATTTA
+TTAAGGAGCATTGTTCATTTACAGTTTTGTACTCTCAGAGCGTGTTATTATCTAGAAGCAATTGTATACTGTTCTCAGTA
+CATGTAGTACCTCCCCCAGAATACTTGTTTCTGTTACTATGTACCCCTCTTATTAACTTCGGGATATGAAACTTTTTATG
+TTTCATTTTCTATTGATTTCATTTGTTTGTCATTTTCAAGCTCCTCTTTCCACATAAGCTTTAACTGCATGTCTTTCATT
+TTTATTTATTTCTATTTGCCAATTGTTTAACTATGCACACATTTGTTTCATGTTTCTCCAGAGATAACTTTCCCAAATTC
+AAGTTTGCGCCAACTCGTGCTGCTCTTTTATTGTACGGTTTTATAACGTTTCCGTCTTGAAATCAGAGATTGTAGCCGTT
+TTTTGAAAAGGATATGCCAAAGAATCGTCCCCCACCCTCTAGTTGTCATTTGTTAAATAGCCGAAGTGACCCAACAACCC
+GCTTTTGTCCCCTCTACTAATAACCGTTTTATTATTATTATCACTCAATATTTATCTTTTTATGTACTTCTTTCACTGCT
+CCCATGTCGTGATTTCTGATTTCACATTTTCCAGACTATCTCGCACTTTCATTCTACCTCAATACATCCCAGCTTTTTTG
+CCATACATTCTCCGATTCGAATTCATGTGTGCTCGTTTAACTATTATTACCTGTATCCACCGATTACTTTTTTGTTTATT
+CGCTCCCTTTTTTCTATCTCAGGAATGATTTATAGTTTTCAATTTGTCTTCTCACAACTCATCTAAACTACTTGTCCGCT
+ACCTTATGTACCTCATTGACTCATTTTGCCATCACCCAATACAATTTATACCTCAATACTGTCTCTTACCTGTATAATGC
+CTTCTACCTCCAATTTTTACCATCTATTCTAGTTAATTACCATTTTCTACCTCAACCCATTTTCTATTATACAACCGTTC
+CACCTCAAACTTCAGTGCGTTCTTCTGTCATCATGTACAATTTTCTTTCTTCGAATTTTGATTCGAATGTCAATTTATCA
+ATTTATAAAAACTCCAATAAAAAAGCATCTTGAAGCATCTTGTTTTACCACATATATCAAAACTTCAAAGTACACAATTA
+ATCGGATCATCAGAAAAA
Added: trunk/packages/rnahybrid/branches/upstream/current/examples/cel-let-7.fasta
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/examples/cel-let-7.fasta (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/examples/cel-let-7.fasta 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,2 @@
+>cel-let-7
+ugagguaguagguuguauaguu
Added: trunk/packages/rnahybrid/branches/upstream/current/examples/coding_fly.freq
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/examples/coding_fly.freq (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/examples/coding_fly.freq 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,17 @@
+# dinucleotide frequencies from D. melanogaster coding sequence
+AA: 0.0660328
+AC: 0.0611442
+AG: 0.068442
+AT: 0.0565617
+CA: 0.0815035
+CC: 0.0683901
+CG: 0.0653833
+CT: 0.0571172
+GA: 0.0734895
+GC: 0.0828927
+GG: 0.0674454
+GT: 0.0467295
+TA: 0.0306786
+TC: 0.059933
+TG: 0.0692581
+TT: 0.0449983
Added: trunk/packages/rnahybrid/branches/upstream/current/examples/coding_worm.freq
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/examples/coding_worm.freq (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/examples/coding_worm.freq 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,17 @@
+# dinucleotide frequencies from C. elegans coding sequence
+AA: 0.103789
+AC: 0.0565921
+AG: 0.0607529
+AT: 0.0817754
+CA: 0.0739273
+CC: 0.0398698
+CG: 0.0433821
+CT: 0.0545018
+GA: 0.0838167
+GC: 0.044407
+GG: 0.0442801
+GT: 0.0483436
+TA: 0.0412813
+TC: 0.0708102
+TG: 0.0725687
+TT: 0.0799021
Added: trunk/packages/rnahybrid/branches/upstream/current/examples/hbl-1.fasta
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/examples/hbl-1.fasta (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/examples/hbl-1.fasta 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,40 @@
+>F13D11.2.1|F13D11.2.1 assembly=CEL116|chr=X|strand=forward|downstream UTR
+TGAGGACGTCCTCGTTAAGGAAACACTTCCCATAGCCCCTTACCCTCGTCTAGTGACCCATTCTGAAATCGGCAGATAGA
+CTTTCATGTAGCTGGTTTAAGTTTTCTCTTCATTTTCTTTAACTTATCAATGTTCGGGCGTTACCACTTTTCTAATCATG
+GCCAGTTTCTTGCACGTACACCTCAACCGTCCATTTCCATGAAATCTCATACTTGTTACTGTTTTCTTTTACCTCTGATG
+TCACATTTTCTCTCTGTCTCACTTTCTACCTCCAAACATATTTTACTACTTGTATTGAATGCCAAAAAATACCATATTTA
+TTAAGGAGCATTGTTCATTTACAGTTTTGTACTCTCAGAGCGTGTTATTATCTAGAAGCAATTGTATACTGTTCTCAGTA
+CATGTAGTACCTCCCCCAGAATACTTGTTTCTGTTACTATGTACCCCTCTTATTAACTTCGGGATATGAAACTTTTTATG
+TTTCATTTTCTATTGATTTCATTTGTTTGTCATTTTCAAGCTCCTCTTTCCACATAAGCTTTAACTGCATGTCTTTCATT
+TTTATTTATTTCTATTTGCCAATTGTTTAACTATGCACACATTTGTTTCATGTTTCTCCAGAGATAACTTTCCCAAATTC
+AAGTTTGCGCCAACTCGTGCTGCTCTTTTATTGTACGGTTTTATAACGTTTCCGTCTTGAAATCAGAGATTGTAGCCGTT
+TTTTGAAAAGGATATGCCAAAGAATCGTCCCCCACCCTCTAGTTGTCATTTGTTAAATAGCCGAAGTGACCCAACAACCC
+GCTTTTGTCCCCTCTACTAATAACCGTTTTATTATTATTATCACTCAATATTTATCTTTTTATGTACTTCTTTCACTGCT
+CCCATGTCGTGATTTCTGATTTCACATTTTCCAGACTATCTCGCACTTTCATTCTACCTCAATACATCCCAGCTTTTTTG
+CCATACATTCTCCGATTCGAATTCATGTGTGCTCGTTTAACTATTATTACCTGTATCCACCGATTACTTTTTTGTTTATT
+CGCTCCCTTTTTTCTATCTCAGGAATGATTTATAGTTTTCAATTTGTCTTCTCACAACTCATCTAAACTACTTGTCCGCT
+ACCTTATGTACCTCATTGACTCATTTTGCCATCACCCAATACAATTTATACCTCAATACTGTCTCTTACCTGTATAATGC
+CTTCTACCTCCAATTTTTACCATCTATTCTAGTTAATTACCATTTTCTACCTCAACCCATTTTCTATTATACAACCGTTC
+CACCTCAAACTTCAGTGCGTTCTTCTGTCATCATGTACAATTTTCTTTCTTCGAATTTTGATTCGAATGTCAATTTATCA
+ATTTATAAAAACTCCAATAAAAAAGCATCTTGAAGCATCTTGTTTTACCACATATATCAAAACTTCAAAGTACACAATTA
+ATCGGATCATCAGAAAAA
+>ENSCBRT00000006770.1|ENSCBRG00000005546.1 assembly=CBR25|chr=cb25.fpc3857|strand=forward|downstream UTR
+TGAAGACTTCTCCCTTCATAGTCTTACCCTCATCTAGTCGACGAAACTTCCATTTGGGAATAGACTCGTTTTGTAGCTGG
+TTTTTCTTTTCCTAATATTTTAACTTATCAATGTTCGGGCGTTTTGTTATTTGTTTCCTTTTTTAATCTTGGCCATGTTC
+TTGCAATTGTACCTCAAACCATCCATTTCCATGGAATCTCAAAACCACTAGTTATCACTATATACTTTTTCTGTTTATCA
+TCCCTACCTCAAAACATATTCCCGTACTTGTTTCAATGACGCCAAAACGAAAATACCTAAAAGAGCCTTACTCTCTGTAC
+CCCCAATCTATTAAACGTGTCACTCTTAGAAGCAATTGTATACTGTTTGCCAAAGTACATGTAGTACCCCTTCTCCTCCA
+GAATACTTGTTTCTGTTACTATGTACCTTCTCAATATTTCGGGATATGGAAATTTTTCTTTGCGTGCTCCAAAAAAACCT
+TCAAATGATTTCATTCTCATTTTTTCTCAATTTCTAAGGCCCCTTCTCCACTAATAAGCTTTATTCTCTTTTGCATGTCT
+TTCAAACAACTTATTTATTTTCTATTCACCCAATTTTTTAATATGTGCATGATTCTTCTTTCTTGTTATAGCATTTTGTG
+TATTTTCCCCTTAATTATAGCCCCCTACAACCGTCCCCCTACCTCTCTCCCCAAAAATCATACGAACTCAGATTGTATTG
+CAGTTTTAACCGTTTCGAACTAGAATTCATGCCAATGATTCGTTTTTCATCTAGTTTGTCATTACTTTTTTTCATAACCG
+AAGTGACTTTTTCCCAAACCCGCTTACAACTTTTCTACCCCATCAAGCAATTTAATAATAACCGTTTTTTTTTGTTCATG
+CTACCTCAATTTGCTTATGTACCTCTTTCAAAAACTCCCATGTCCTCCCAAAAATTCTGATTTCAGTCTCCCCCTTACCT
+TCATACATCCCAAGCCTTTTGCCATACATTCTCCGTTTCAACCTAATTGCGTGCTTATTATTCATCCTTTGTATAGCCTT
+TTCAGCTTCATCAAAATTTATTGGCCCACCTCATCTCCCAGAACTCATCTCAGGAATTTACTATGCTCCATTTTCAGTAA
+AAACCTCCTCCTCTCTATGAACTACTTGTCTCTTGATTACTGTTATCCAATATTATGTACCTCATTGAATTTGCCATCCC
+CAATCCTTTTTTCTTTACCTCAAACTCATTTTTTCTCTCCATACTGGCCTATGACTGTATAATGCGTTCTACCTCCCCAA
+CTGTCCCCAATTCTAGTTATGTACCGTTTTTCTACCTCAAAAAATTAAACCCCATTATACAACCGTTCCACCTCAAACTC
+CCTCCCTTTTAGTCATGTACAATTTCTCTATCTCAAGTCGTATTCGGCTTCCACTATGAAAAATCCAATCCAATAAAAAT
+CATCATTAA
Added: trunk/packages/rnahybrid/branches/upstream/current/install-sh
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/install-sh (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/install-sh 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,276 @@
+#!/bin/sh
+#
+# install - install a program, script, or datafile
+# This comes from X11R5 (mit/util/scripts/install.sh).
+#
+# Copyright 1991 by the Massachusetts Institute of Technology
+#
+# Permission to use, copy, modify, distribute, and sell this software and its
+# documentation for any purpose is hereby granted without fee, provided that
+# the above copyright notice appear in all copies and that both that
+# copyright notice and this permission notice appear in supporting
+# documentation, and that the name of M.I.T. not be used in advertising or
+# publicity pertaining to distribution of the software without specific,
+# written prior permission. M.I.T. makes no representations about the
+# suitability of this software for any purpose. It is provided "as is"
+# without express or implied warranty.
+#
+# Calling this script install-sh is preferred over install.sh, to prevent
+# `make' implicit rules from creating a file called install from it
+# when there is no Makefile.
+#
+# This script is compatible with the BSD install script, but was written
+# from scratch. It can only install one file at a time, a restriction
+# shared with many OS's install programs.
+
+
+# set DOITPROG to echo to test this script
+
+# Don't use :- since 4.3BSD and earlier shells don't like it.
+doit="${DOITPROG-}"
+
+
+# put in absolute paths if you don't have them in your path; or use env. vars.
+
+mvprog="${MVPROG-mv}"
+cpprog="${CPPROG-cp}"
+chmodprog="${CHMODPROG-chmod}"
+chownprog="${CHOWNPROG-chown}"
+chgrpprog="${CHGRPPROG-chgrp}"
+stripprog="${STRIPPROG-strip}"
+rmprog="${RMPROG-rm}"
+mkdirprog="${MKDIRPROG-mkdir}"
+
+transformbasename=""
+transform_arg=""
+instcmd="$mvprog"
+chmodcmd="$chmodprog 0755"
+chowncmd=""
+chgrpcmd=""
+stripcmd=""
+rmcmd="$rmprog -f"
+mvcmd="$mvprog"
+src=""
+dst=""
+dir_arg=""
+
+while [ x"$1" != x ]; do
+ case $1 in
+ -c) instcmd=$cpprog
+ shift
+ continue;;
+
+ -d) dir_arg=true
+ shift
+ continue;;
+
+ -m) chmodcmd="$chmodprog $2"
+ shift
+ shift
+ continue;;
+
+ -o) chowncmd="$chownprog $2"
+ shift
+ shift
+ continue;;
+
+ -g) chgrpcmd="$chgrpprog $2"
+ shift
+ shift
+ continue;;
+
+ -s) stripcmd=$stripprog
+ shift
+ continue;;
+
+ -t=*) transformarg=`echo $1 | sed 's/-t=//'`
+ shift
+ continue;;
+
+ -b=*) transformbasename=`echo $1 | sed 's/-b=//'`
+ shift
+ continue;;
+
+ *) if [ x"$src" = x ]
+ then
+ src=$1
+ else
+ # this colon is to work around a 386BSD /bin/sh bug
+ :
+ dst=$1
+ fi
+ shift
+ continue;;
+ esac
+done
+
+if [ x"$src" = x ]
+then
+ echo "$0: no input file specified" >&2
+ exit 1
+else
+ :
+fi
+
+if [ x"$dir_arg" != x ]; then
+ dst=$src
+ src=""
+
+ if [ -d "$dst" ]; then
+ instcmd=:
+ chmodcmd=""
+ else
+ instcmd=$mkdirprog
+ fi
+else
+
+# Waiting for this to be detected by the "$instcmd $src $dsttmp" command
+# might cause directories to be created, which would be especially bad
+# if $src (and thus $dsttmp) contains '*'.
+
+ if [ -f "$src" ] || [ -d "$src" ]
+ then
+ :
+ else
+ echo "$0: $src does not exist" >&2
+ exit 1
+ fi
+
+ if [ x"$dst" = x ]
+ then
+ echo "$0: no destination specified" >&2
+ exit 1
+ else
+ :
+ fi
+
+# If destination is a directory, append the input filename; if your system
+# does not like double slashes in filenames, you may need to add some logic
+
+ if [ -d "$dst" ]
+ then
+ dst=$dst/`basename "$src"`
+ else
+ :
+ fi
+fi
+
+## this sed command emulates the dirname command
+dstdir=`echo "$dst" | sed -e 's,[^/]*$,,;s,/$,,;s,^$,.,'`
+
+# Make sure that the destination directory exists.
+# this part is taken from Noah Friedman's mkinstalldirs script
+
+# Skip lots of stat calls in the usual case.
+if [ ! -d "$dstdir" ]; then
+defaultIFS='
+ '
+IFS="${IFS-$defaultIFS}"
+
+oIFS=$IFS
+# Some sh's can't handle IFS=/ for some reason.
+IFS='%'
+set - `echo "$dstdir" | sed -e 's@/@%@g' -e 's@^%@/@'`
+IFS=$oIFS
+
+pathcomp=''
+
+while [ $# -ne 0 ] ; do
+ pathcomp=$pathcomp$1
+ shift
+
+ if [ ! -d "$pathcomp" ] ;
+ then
+ $mkdirprog "$pathcomp"
+ else
+ :
+ fi
+
+ pathcomp=$pathcomp/
+done
+fi
+
+if [ x"$dir_arg" != x ]
+then
+ $doit $instcmd "$dst" &&
+
+ if [ x"$chowncmd" != x ]; then $doit $chowncmd "$dst"; else : ; fi &&
+ if [ x"$chgrpcmd" != x ]; then $doit $chgrpcmd "$dst"; else : ; fi &&
+ if [ x"$stripcmd" != x ]; then $doit $stripcmd "$dst"; else : ; fi &&
+ if [ x"$chmodcmd" != x ]; then $doit $chmodcmd "$dst"; else : ; fi
+else
+
+# If we're going to rename the final executable, determine the name now.
+
+ if [ x"$transformarg" = x ]
+ then
+ dstfile=`basename "$dst"`
+ else
+ dstfile=`basename "$dst" $transformbasename |
+ sed $transformarg`$transformbasename
+ fi
+
+# don't allow the sed command to completely eliminate the filename
+
+ if [ x"$dstfile" = x ]
+ then
+ dstfile=`basename "$dst"`
+ else
+ :
+ fi
+
+# Make a couple of temp file names in the proper directory.
+
+ dsttmp=$dstdir/#inst.$$#
+ rmtmp=$dstdir/#rm.$$#
+
+# Trap to clean up temp files at exit.
+
+ trap 'status=$?; rm -f "$dsttmp" "$rmtmp" && exit $status' 0
+ trap '(exit $?); exit' 1 2 13 15
+
+# Move or copy the file name to the temp name
+
+ $doit $instcmd "$src" "$dsttmp" &&
+
+# and set any options; do chmod last to preserve setuid bits
+
+# If any of these fail, we abort the whole thing. If we want to
+# ignore errors from any of these, just make sure not to ignore
+# errors from the above "$doit $instcmd $src $dsttmp" command.
+
+ if [ x"$chowncmd" != x ]; then $doit $chowncmd "$dsttmp"; else :;fi &&
+ if [ x"$chgrpcmd" != x ]; then $doit $chgrpcmd "$dsttmp"; else :;fi &&
+ if [ x"$stripcmd" != x ]; then $doit $stripcmd "$dsttmp"; else :;fi &&
+ if [ x"$chmodcmd" != x ]; then $doit $chmodcmd "$dsttmp"; else :;fi &&
+
+# Now remove or move aside any old file at destination location. We try this
+# two ways since rm can't unlink itself on some systems and the destination
+# file might be busy for other reasons. In this case, the final cleanup
+# might fail but the new file should still install successfully.
+
+{
+ if [ -f "$dstdir/$dstfile" ]
+ then
+ $doit $rmcmd -f "$dstdir/$dstfile" 2>/dev/null ||
+ $doit $mvcmd -f "$dstdir/$dstfile" "$rmtmp" 2>/dev/null ||
+ {
+ echo "$0: cannot unlink or rename $dstdir/$dstfile" >&2
+ (exit 1); exit
+ }
+ else
+ :
+ fi
+} &&
+
+# Now rename the file to the real destination.
+
+ $doit $mvcmd "$dsttmp" "$dstdir/$dstfile"
+
+fi &&
+
+# The final little trick to "correctly" pass the exit status to the exit trap.
+
+{
+ (exit 0); exit
+}
Property changes on: trunk/packages/rnahybrid/branches/upstream/current/install-sh
___________________________________________________________________
Name: svn:executable
+
Added: trunk/packages/rnahybrid/branches/upstream/current/man/Makefile.am
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/man/Makefile.am (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/man/Makefile.am 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,2 @@
+man_MANS = RNAhybrid.1 RNAcalibrate.1 RNAeffective.1
+EXTRA_DIST = $(man_MANS)
Added: trunk/packages/rnahybrid/branches/upstream/current/man/Makefile.in
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/man/Makefile.in (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/man/Makefile.in 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,299 @@
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+ ext=`echo $$i | sed -e 's/^.*\\.//'`; \
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+ echo " rm -f $(DESTDIR)$(man1dir)/$$inst"; \
+ rm -f $(DESTDIR)$(man1dir)/$$inst; \
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+distdir: $(DISTFILES)
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+ $(srcdir)/*) file=`echo "$$file" | sed "s|^$$srcdirstrip/||"`;; \
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+# Tell versions [3.59,3.63) of GNU make to not export all variables.
+# Otherwise a system limit (for SysV at least) may be exceeded.
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Added: trunk/packages/rnahybrid/branches/upstream/current/man/RNAcalibrate.1
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/man/RNAcalibrate.1 (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/man/RNAcalibrate.1 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,108 @@
+.TH RNACALIBRATE 1
+.ER
+.SH NAME
+RNAcalibrate \- calibrate statistics of secondary structure hybridisations of
+RNAs
+.SH SYNOPSIS
+\fBRNAcalibrate [\-h] [\-d \fIfrequency_file\fB] [\-f \fIfrom,to\fB] [\-k
+\fIsample_size\fB] [\-l \fImean,std\fB] [\-m \fImax_target_length\fB] [\-n
+\fImax_query_length\fB] [\-u \fIiloop_upper_limit\fB] [\-v
+\fIbloop_upper_limit\fB] [\-s] [\-t \fItarget_file\fB] [\-q \fIquery_file\fB]
+[\fItarget\fB] [\fIquery\fB]
+
+.SH DESCRIPTION
+.I RNAcalibrate
+is a tool for calibrating minimum free energy (mfe) hybridisations performed
+with RNAhybrid. It searches a random database that can be given on the command
+line or otherwise generates random sequences according to given sample size,
+length distribution parameters and dinucleotide frequencies. To the empirical
+distribution of length normalised minimum free energies, parameters of an
+extreme value distribution (evd) are fitted. The output gives for each miRNA
+its name (or "command_line" if it was submitted on the command line), the
+number of data points the evd fit was done on, the location and the scale
+parameter. The location and scale parameters of the evd can then be given to
+RNAhybrid for the calculation of mfe p-values.
+
+.SH OPTIONS
+.TP
+.B \-h
+Give a short summary of command line options.
+.TP
+.B \-d \fIfrequency_file
+Generate random sequences according to dinucleotide frequencies
+given in \fIfrequency_file\fP. See example directory for example
+files.
+.TP
+.B \-f \fIfrom,to
+Forces all structures to have a helix from position \fIfrom\fP to position
+\fIto\fP with respect to the query. The first base has position 1.
+.TP
+.B \-k \fIsample_size
+Generate \fIsample_size\fP random sequences. Default value is 5000.
+.TP
+.B \-l \fImean,std
+Generate random sequences with a normal length distribution of
+mean \fImean\fP and standard deviation \fIstd\fP. Default values are 500 and
+300, respectively.
+.TP
+.B \-m \fImax_target_length
+The maximum allowed length of a target sequence. The default value is
+2000. This option only has an effect if a target file is given with the \-t
+option (see below).
+.TP
+.B \-n \fImax_query_length
+The maximum allowed length of a query sequence. The default value is 30. This
+option only has an effect if a query file is given with the \-q option (see
+below).
+.TP
+.B \-u \fIiloop_upper_limit
+The maximally allowed number of unpaired nucleotides in either side of an
+internal loop.
+.TP
+.B \-v \fIbloop_upper_limit
+The maximally allowed number of unpaired nucleotides in a bulge loop.
+.TP
+.B \-s
+Generate random sequences according to the dinucleotide distribution of given
+targets (either with the \-t option or on command line. If no \-t is given,
+either the last argument (if a \-q is given) or the second last argument (if no
+\-q is given) to RNAcalibrate is taken as a target). See \-t option.
+.TP
+.B \-t \fItarget_file
+Without the \-s option, each of the target sequences in \fItarget_file\fP is
+subject to hybridisation with each of the queries (which either are from the
+\fIquery_file\fP or is the one query given on command line; see \-q below). The
+sequences in the \fItarget_file\fP have to be in FASTA format, ie. one line
+starting with a \> and directly followed by a name, then one or more following
+lines with the sequence itself. Each individual sequence line must not have
+more than 1000 characters.
+
+With the \-s option, the target (or target file) dinucleotide distribution is
+counted, and random sequences are generated according to this distribution.
+
+If no \-t is given, random sequences are generated as described above
+(see \-d option).
+.TP
+.B \-q \fIquery_file
+See \-t option above. If no \-q is given, the last argument to RNAcalibrate is
+taken as a query.
+.SH REFERENCES
+The energy parameters are taken from:
+
+Mathews DH, Sabina J, Zuker M, Turner DH.
+"Expanded sequence dependence of thermodynamic parameters improves
+prediction of RNA secondary structure"
+J Mol Biol., 288 (5), pp 911-940, 1999
+
+.SH VERSION
+This man page documents version 2.0 of RNAcalibrate.
+
+.SH AUTHORS
+Marc Rehmsmeier, Peter Steffen, Matthias Hoechsmann.
+
+.SH LIMITATIONS
+Character dependent energy values are only defined for [acgtuACGTU].
+All other characters lead to values of zero in these cases.
+
+.SH SEE ALSO
+RNAhybrid, RNAeffective
Added: trunk/packages/rnahybrid/branches/upstream/current/man/RNAeffective.1
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/man/RNAeffective.1 (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/man/RNAeffective.1 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,102 @@
+.TH RNAEFFECTIVE 1
+.ER
+.SH NAME
+RNAeffective \- calculation of effective numbers of orthologous miRNA targets
+.SH SYNOPSIS
+\fBRNAeffective [\-h] [\-d \fIfrequency_file\fB] [\-f \fIfrom,to\fB] [\-k
+\fIsample_size\fB] [\-l \fImean,std\fB] [\-m \fImax_target_length\fB] [\-n
+\fImax_query_length\fB] [\-u \fIiloop_upper_limit\fB] [\-v
+\fIbloop_upper_limit\fB] [\-s] [\-t \fItarget_file\fB] [\-q \fIquery_file\fB]
+[\fIquery\fB]
+
+.SH DESCRIPTION
+.I RNAeffective
+is a tool for determining the effective number of orthologous miRNA targets.
+This number can be used for the calculation of more accurate joint p-values in
+multi-species analyses. RNAeffective searches a set of target sequences with
+random miRNAs that can be given on the command line or otherwise generates
+random sequences according to given sample size, length distribution parameters
+and dinucleotide frequencies. The empirical distribution of joint p-values is
+compared to the p-values themselves, and the effective number of independent
+targets is the one that reduces the deviation between the two distributions.
+
+.SH OPTIONS
+.TP
+.B \-h
+Give a short summary of command line options.
+.TP
+.B \-d \fIfrequency_file
+Generate random sequences according to dinucleotide frequencies
+given in \fIfrequency_file\fP. See example directory for example
+files.
+.TP
+.B \-f \fIfrom,to
+Forces all structures to have a helix from position \fIfrom\fP to position
+\fIto\fP with respect to the query. The first base has position 1.
+.TP
+.B \-k \fIsample_size
+Generate \fIsample_size\fP random sequences. Default value is 5000.
+.TP
+.B \-l \fImean,std
+Generate random sequences with a normal length distribution of
+mean \fImean\fP and standard deviation \fIstd\fP. Default values are 22 and
+0, respectively.
+.TP
+.B \-m \fImax_target_length
+The maximum allowed length of a target sequence. The default value is
+2000. This option only has an effect if a target file is given with the \-t
+option (see below).
+.TP
+.B \-n \fImax_query_length
+The maximum allowed length of a query sequence. The default value is 30. This
+option only has an effect if a query file is given with the \-q option (see
+below).
+.TP
+.B \-u \fIiloop_upper_limit
+The maximally allowed number of unpaired nucleotides in either side of an
+internal loop.
+.TP
+.B \-v \fIbloop_upper_limit
+The maximally allowed number of unpaired nucleotides in a bulge loop.
+.TP
+.B \-s
+Generate random sequences according to the dinucleotide distribution of given
+queries (either with the \-q option or on command line. If no \-q is given,
+the last argument to RNAeffective is taken as a query). See \-q option.
+.TP
+.B \-q \fIquery_file
+Without the \-s option, each of the query sequences in \fIquery_file\fP is
+subject to hybridisation with each of the targets (which are from the
+\fItarget_file\fP; see \-t below). The sequences in the \fIquery_file\fP have
+to be in FASTA format, ie. one line starting with a \> and directly followed by
+a name, then one or more following lines with the sequence itself. Each
+individual sequence line must not have more than 1000 characters.
+
+With the \-s option, the query (or query file) dinucleotide distribution is
+counted, and random sequences are generated according to this distribution.
+
+If no \-q is given, random sequences are generated as described above
+(see \-d option).
+.TP
+.B \-t \fItarget_file
+See \-q option above.
+.SH REFERENCES
+The energy parameters are taken from:
+
+Mathews DH, Sabina J, Zuker M, Turner DH.
+"Expanded sequence dependence of thermodynamic parameters improves
+prediction of RNA secondary structure"
+J Mol Biol., 288 (5), pp 911-940, 1999
+
+.SH VERSION
+This man page documents version 2.0 of RNAeffective.
+
+.SH AUTHORS
+Marc Rehmsmeier, Peter Steffen, Matthias Hoechsmann.
+
+.SH LIMITATIONS
+Character dependent energy values are only defined for [acgtuACGTU].
+All other characters lead to values of zero in these cases.
+
+.SH SEE ALSO
+RNAhybrid, RNAcalibrate
Added: trunk/packages/rnahybrid/branches/upstream/current/man/RNAhybrid.1
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/man/RNAhybrid.1 (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/man/RNAhybrid.1 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,141 @@
+.TH RNAHYBRID 1
+.ER
+.SH NAME
+RNAhybrid \- calculate secondary structure hybridisations of RNAs
+.SH SYNOPSIS
+\fBRNAhybrid [\-h] [\-b \fIhit_number\fB] [\-e \fIenergy_cutoff\fB] [\-p
+\fIp-value_cutoff\fB] [\-c] [\-d \fIxi,theta\fB] [\-s \fIset_name\fB] [\-f
+\fIfrom,to\fB] [\-m \fImax_target_length\fB] [\-n \fImax_query_length\fB] [\-u
+\fIiloop_upper_limit\fB] [\-v \fIbloop_upper_limit\fB] [\-g (ps|png|jpg|all)]
+[\-t \fItarget_file\fB] [\-q \fIquery_file\fB] [\fItarget\fB] [\fIquery\fB]
+
+.SH DESCRIPTION
+.I RNAhybrid
+is a tool for finding minimum free energy (mfe) hybridisations of a long
+(target) and a short (query) RNA. The hybridisation is performed in a kind of
+domain mode, ie. the short sequence is hybridised to the best fitting parts of
+the long one. The tool is primarily meant as a means for microRNA target
+prediction. In addition to mfes, the program calculates p-values based on
+extreme value distributions of length normalised energies.
+
+.SH OPTIONS
+.TP
+.B \-h
+Give a short summary of command line options.
+.TP
+.B \-b \fIhit_number
+Maximal number of hits to show. \fIhit_number\fP hits with increasing minimum
+free energy (reminder: larger energies are worse) are shown, unless the \-e
+option is used and the energy cut-off has been exceeded (see \-e option below) or
+there are no more hits. Hits may only overlap at dangling bases (5' or 3'
+unpaired end of target).
+.TP
+.B \-c
+Produce compact output. For each target/query pair one line of output
+is generated. Each line is a colon (:) separated list of the following
+fields: target name, query name, minimum free energy, position in target,
+alignment line 1, line 2, line 3, line 4. If a target or a query is given
+on command line (ie. no \-t or \-q respectively), its name in the output
+will be "command line".
+.TP
+.B \-d \fIxi,theta
+xi and theta are the position and shape parameters, respectively, of an extreme
+value distribution (evd). p-values of duplex energies are assumed to be
+distributed according to such an evd. For a length normalised energy en, we
+have P[X <= en] = 1 - exp(-exp(-(-en-xi)/theta)), where en = e/log(m*n) with m
+and n being the lengths of the target and the query, respectively. If the \-d
+option is omitted, xi and theta are estimated from the maximal duplex energy of
+the query, assuming a linear dependence. The parameters of this linear
+dependence are coded into the program, but the option \-s has to be given to
+choose from the appropriate set. Note that the evd is mirrored, since good mfes
+are large negative values.
+.TP
+.B \-s \fIset_name
+Used for quick estimate of extreme value distribution parameters (see \-d
+option above). Tells RNAhybrid which target dataset to assume. Valid parameters
+are 3utr_fly, 3utr_worm and 3utr_human.
+.TP
+.B \-e \fIenergy_cutoff
+Hits with increasing minimum free energy (reminder: larger energies are worse)
+less than or equal to \fIenergy_cutoff\fP are shown, unless the \-b option is
+used and the number of already reported hits has reached the maximal
+\fIhit_number\fP (see \-b option above). Hits may only overlap at dangling
+bases (5' or 3' unpaired end of target).
+.TP
+.B \-p \fIp-value_cutoff
+Only hits with p-values not larger than \fIp-value_cutoff\fP are reported.
+See also options \-d and \-s.
+.TP
+.B \-f \fIfrom,to
+Forces all structures to have a helix from position \fIfrom\fP to position
+\fIto\fP with respect to the query. The first base has position 1.
+.TP
+.B \-m \fImax_target_length
+The maximum allowed length of a target sequence. The default value is
+2000. This option only has an effect if a target file is given with the \-t
+option (see below).
+.TP
+.B \-n \fImax_query_length
+The maximum allowed length of a query sequence. The default value is 30. This
+option only has an effect if a query file is given with the \-q option (see
+below).
+.TP
+.B \-u \fIiloop_upper_limit
+The maximally allowed number of unpaired nucleotides in either side of an
+internal loop.
+.TP
+.B \-v \fIbloop_upper_limit
+The maximally allowed number of unpaired nucleotides in a bulge loop.
+.TP
+.B \-g (ps|png|jpg|all)
+Produce a plot of the hybridisation, either in ps, png or jpg format,
+or for all formats together. The plots are saved in files whose names are
+created from the target and query names ("command_line" if given on the
+command line). This option only works, if the appropriate graphics libraries
+are present.
+.TP
+.B \-t \fItarget_file
+Each of the target sequences in \fItarget_file\fP is subject to hybridisation
+with each of the queries (which either are from the \fIquery_file\fP or is the
+one query given on command line; see \-q below). The sequences in the
+\fItarget_file\fP have to be in FASTA format, ie. one line starting with a \>
+and directly followed by a name, then one or more following lines with the
+sequence itself. Each individual sequence line must not have more than 1000
+characters. If no \-t is given, either the last argument (if a \-q is given)
+or the second last argument (if no \-q is given) to RNAhybrid is taken as a
+target.
+.TP
+.B \-q \fIquery_file
+See \-t option above.
+.SH REFERENCES
+The energy parameters are taken from:
+
+Mathews DH, Sabina J, Zuker M, Turner DH.
+"Expanded sequence dependence of thermodynamic parameters improves
+prediction of RNA secondary structure"
+J Mol Biol., 288 (5), pp 911-940, 1999
+
+The graphical output uses code from the Vienna RNA package:
+
+Hofacker IL.
+"Vienna RNA secondary structure server."
+Nucleic Acids Research, 31 (13), pp 3429-3431, 2003
+
+.SH VERSION
+This man page documents version 2.0 of RNAhybrid.
+
+.SH AUTHORS
+Marc Rehmsmeier, Peter Steffen, Matthias Hoechsmann.
+
+.SH LIMITATIONS
+Character dependent energy values are only defined for [acgtuACGTU].
+All other characters lead to values of zero in these cases.
+
+
+.SH BUGS
+In suboptimal hits, dangling ends appear as Ns if they were in the
+first or last hybridising position of a previous hit.
+
+
+.SH SEE ALSO
+RNAcalibrate, RNAeffective
Added: trunk/packages/rnahybrid/branches/upstream/current/missing
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/missing (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/missing 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,336 @@
+#! /bin/sh
+# Common stub for a few missing GNU programs while installing.
+# Copyright (C) 1996, 1997, 1999, 2000, 2002 Free Software Foundation, Inc.
+# Originally by Fran,cois Pinard <pinard at iro.umontreal.ca>, 1996.
+
+# This program is free software; you can redistribute it and/or modify
+# it under the terms of the GNU General Public License as published by
+# the Free Software Foundation; either version 2, or (at your option)
+# any later version.
+
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
+# GNU General Public License for more details.
+
+# You should have received a copy of the GNU General Public License
+# along with this program; if not, write to the Free Software
+# Foundation, Inc., 59 Temple Place - Suite 330, Boston, MA
+# 02111-1307, USA.
+
+# As a special exception to the GNU General Public License, if you
+# distribute this file as part of a program that contains a
+# configuration script generated by Autoconf, you may include it under
+# the same distribution terms that you use for the rest of that program.
+
+if test $# -eq 0; then
+ echo 1>&2 "Try \`$0 --help' for more information"
+ exit 1
+fi
+
+run=:
+
+# In the cases where this matters, `missing' is being run in the
+# srcdir already.
+if test -f configure.ac; then
+ configure_ac=configure.ac
+else
+ configure_ac=configure.in
+fi
+
+case "$1" in
+--run)
+ # Try to run requested program, and just exit if it succeeds.
+ run=
+ shift
+ "$@" && exit 0
+ ;;
+esac
+
+# If it does not exist, or fails to run (possibly an outdated version),
+# try to emulate it.
+case "$1" in
+
+ -h|--h|--he|--hel|--help)
+ echo "\
+$0 [OPTION]... PROGRAM [ARGUMENT]...
+
+Handle \`PROGRAM [ARGUMENT]...' for when PROGRAM is missing, or return an
+error status if there is no known handling for PROGRAM.
+
+Options:
+ -h, --help display this help and exit
+ -v, --version output version information and exit
+ --run try to run the given command, and emulate it if it fails
+
+Supported PROGRAM values:
+ aclocal touch file \`aclocal.m4'
+ autoconf touch file \`configure'
+ autoheader touch file \`config.h.in'
+ automake touch all \`Makefile.in' files
+ bison create \`y.tab.[ch]', if possible, from existing .[ch]
+ flex create \`lex.yy.c', if possible, from existing .c
+ help2man touch the output file
+ lex create \`lex.yy.c', if possible, from existing .c
+ makeinfo touch the output file
+ tar try tar, gnutar, gtar, then tar without non-portable flags
+ yacc create \`y.tab.[ch]', if possible, from existing .[ch]"
+ ;;
+
+ -v|--v|--ve|--ver|--vers|--versi|--versio|--version)
+ echo "missing 0.4 - GNU automake"
+ ;;
+
+ -*)
+ echo 1>&2 "$0: Unknown \`$1' option"
+ echo 1>&2 "Try \`$0 --help' for more information"
+ exit 1
+ ;;
+
+ aclocal*)
+ if test -z "$run" && ($1 --version) > /dev/null 2>&1; then
+ # We have it, but it failed.
+ exit 1
+ fi
+
+ echo 1>&2 "\
+WARNING: \`$1' is missing on your system. You should only need it if
+ you modified \`acinclude.m4' or \`${configure_ac}'. You might want
+ to install the \`Automake' and \`Perl' packages. Grab them from
+ any GNU archive site."
+ touch aclocal.m4
+ ;;
+
+ autoconf)
+ if test -z "$run" && ($1 --version) > /dev/null 2>&1; then
+ # We have it, but it failed.
+ exit 1
+ fi
+
+ echo 1>&2 "\
+WARNING: \`$1' is missing on your system. You should only need it if
+ you modified \`${configure_ac}'. You might want to install the
+ \`Autoconf' and \`GNU m4' packages. Grab them from any GNU
+ archive site."
+ touch configure
+ ;;
+
+ autoheader)
+ if test -z "$run" && ($1 --version) > /dev/null 2>&1; then
+ # We have it, but it failed.
+ exit 1
+ fi
+
+ echo 1>&2 "\
+WARNING: \`$1' is missing on your system. You should only need it if
+ you modified \`acconfig.h' or \`${configure_ac}'. You might want
+ to install the \`Autoconf' and \`GNU m4' packages. Grab them
+ from any GNU archive site."
+ files=`sed -n 's/^[ ]*A[CM]_CONFIG_HEADER(\([^)]*\)).*/\1/p' ${configure_ac}`
+ test -z "$files" && files="config.h"
+ touch_files=
+ for f in $files; do
+ case "$f" in
+ *:*) touch_files="$touch_files "`echo "$f" |
+ sed -e 's/^[^:]*://' -e 's/:.*//'`;;
+ *) touch_files="$touch_files $f.in";;
+ esac
+ done
+ touch $touch_files
+ ;;
+
+ automake*)
+ if test -z "$run" && ($1 --version) > /dev/null 2>&1; then
+ # We have it, but it failed.
+ exit 1
+ fi
+
+ echo 1>&2 "\
+WARNING: \`$1' is missing on your system. You should only need it if
+ you modified \`Makefile.am', \`acinclude.m4' or \`${configure_ac}'.
+ You might want to install the \`Automake' and \`Perl' packages.
+ Grab them from any GNU archive site."
+ find . -type f -name Makefile.am -print |
+ sed 's/\.am$/.in/' |
+ while read f; do touch "$f"; done
+ ;;
+
+ autom4te)
+ if test -z "$run" && ($1 --version) > /dev/null 2>&1; then
+ # We have it, but it failed.
+ exit 1
+ fi
+
+ echo 1>&2 "\
+WARNING: \`$1' is needed, and you do not seem to have it handy on your
+ system. You might have modified some files without having the
+ proper tools for further handling them.
+ You can get \`$1Help2man' as part of \`Autoconf' from any GNU
+ archive site."
+
+ file=`echo "$*" | sed -n 's/.*--output[ =]*\([^ ]*\).*/\1/p'`
+ test -z "$file" && file=`echo "$*" | sed -n 's/.*-o[ ]*\([^ ]*\).*/\1/p'`
+ if test -f "$file"; then
+ touch $file
+ else
+ test -z "$file" || exec >$file
+ echo "#! /bin/sh"
+ echo "# Created by GNU Automake missing as a replacement of"
+ echo "# $ $@"
+ echo "exit 0"
+ chmod +x $file
+ exit 1
+ fi
+ ;;
+
+ bison|yacc)
+ echo 1>&2 "\
+WARNING: \`$1' is missing on your system. You should only need it if
+ you modified a \`.y' file. You may need the \`Bison' package
+ in order for those modifications to take effect. You can get
+ \`Bison' from any GNU archive site."
+ rm -f y.tab.c y.tab.h
+ if [ $# -ne 1 ]; then
+ eval LASTARG="\${$#}"
+ case "$LASTARG" in
+ *.y)
+ SRCFILE=`echo "$LASTARG" | sed 's/y$/c/'`
+ if [ -f "$SRCFILE" ]; then
+ cp "$SRCFILE" y.tab.c
+ fi
+ SRCFILE=`echo "$LASTARG" | sed 's/y$/h/'`
+ if [ -f "$SRCFILE" ]; then
+ cp "$SRCFILE" y.tab.h
+ fi
+ ;;
+ esac
+ fi
+ if [ ! -f y.tab.h ]; then
+ echo >y.tab.h
+ fi
+ if [ ! -f y.tab.c ]; then
+ echo 'main() { return 0; }' >y.tab.c
+ fi
+ ;;
+
+ lex|flex)
+ echo 1>&2 "\
+WARNING: \`$1' is missing on your system. You should only need it if
+ you modified a \`.l' file. You may need the \`Flex' package
+ in order for those modifications to take effect. You can get
+ \`Flex' from any GNU archive site."
+ rm -f lex.yy.c
+ if [ $# -ne 1 ]; then
+ eval LASTARG="\${$#}"
+ case "$LASTARG" in
+ *.l)
+ SRCFILE=`echo "$LASTARG" | sed 's/l$/c/'`
+ if [ -f "$SRCFILE" ]; then
+ cp "$SRCFILE" lex.yy.c
+ fi
+ ;;
+ esac
+ fi
+ if [ ! -f lex.yy.c ]; then
+ echo 'main() { return 0; }' >lex.yy.c
+ fi
+ ;;
+
+ help2man)
+ if test -z "$run" && ($1 --version) > /dev/null 2>&1; then
+ # We have it, but it failed.
+ exit 1
+ fi
+
+ echo 1>&2 "\
+WARNING: \`$1' is missing on your system. You should only need it if
+ you modified a dependency of a manual page. You may need the
+ \`Help2man' package in order for those modifications to take
+ effect. You can get \`Help2man' from any GNU archive site."
+
+ file=`echo "$*" | sed -n 's/.*-o \([^ ]*\).*/\1/p'`
+ if test -z "$file"; then
+ file=`echo "$*" | sed -n 's/.*--output=\([^ ]*\).*/\1/p'`
+ fi
+ if [ -f "$file" ]; then
+ touch $file
+ else
+ test -z "$file" || exec >$file
+ echo ".ab help2man is required to generate this page"
+ exit 1
+ fi
+ ;;
+
+ makeinfo)
+ if test -z "$run" && (makeinfo --version) > /dev/null 2>&1; then
+ # We have makeinfo, but it failed.
+ exit 1
+ fi
+
+ echo 1>&2 "\
+WARNING: \`$1' is missing on your system. You should only need it if
+ you modified a \`.texi' or \`.texinfo' file, or any other file
+ indirectly affecting the aspect of the manual. The spurious
+ call might also be the consequence of using a buggy \`make' (AIX,
+ DU, IRIX). You might want to install the \`Texinfo' package or
+ the \`GNU make' package. Grab either from any GNU archive site."
+ file=`echo "$*" | sed -n 's/.*-o \([^ ]*\).*/\1/p'`
+ if test -z "$file"; then
+ file=`echo "$*" | sed 's/.* \([^ ]*\) *$/\1/'`
+ file=`sed -n '/^@setfilename/ { s/.* \([^ ]*\) *$/\1/; p; q; }' $file`
+ fi
+ touch $file
+ ;;
+
+ tar)
+ shift
+ if test -n "$run"; then
+ echo 1>&2 "ERROR: \`tar' requires --run"
+ exit 1
+ fi
+
+ # We have already tried tar in the generic part.
+ # Look for gnutar/gtar before invocation to avoid ugly error
+ # messages.
+ if (gnutar --version > /dev/null 2>&1); then
+ gnutar "$@" && exit 0
+ fi
+ if (gtar --version > /dev/null 2>&1); then
+ gtar "$@" && exit 0
+ fi
+ firstarg="$1"
+ if shift; then
+ case "$firstarg" in
+ *o*)
+ firstarg=`echo "$firstarg" | sed s/o//`
+ tar "$firstarg" "$@" && exit 0
+ ;;
+ esac
+ case "$firstarg" in
+ *h*)
+ firstarg=`echo "$firstarg" | sed s/h//`
+ tar "$firstarg" "$@" && exit 0
+ ;;
+ esac
+ fi
+
+ echo 1>&2 "\
+WARNING: I can't seem to be able to run \`tar' with the given arguments.
+ You may want to install GNU tar or Free paxutils, or check the
+ command line arguments."
+ exit 1
+ ;;
+
+ *)
+ echo 1>&2 "\
+WARNING: \`$1' is needed, and you do not seem to have it handy on your
+ system. You might have modified some files without having the
+ proper tools for further handling them. Check the \`README' file,
+ it often tells you about the needed prerequirements for installing
+ this package. You may also peek at any GNU archive site, in case
+ some other package would contain this missing \`$1' program."
+ exit 1
+ ;;
+esac
+
+exit 0
Property changes on: trunk/packages/rnahybrid/branches/upstream/current/missing
___________________________________________________________________
Name: svn:executable
+
Added: trunk/packages/rnahybrid/branches/upstream/current/mkinstalldirs
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/mkinstalldirs (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/mkinstalldirs 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,111 @@
+#! /bin/sh
+# mkinstalldirs --- make directory hierarchy
+# Author: Noah Friedman <friedman at prep.ai.mit.edu>
+# Created: 1993-05-16
+# Public domain
+
+errstatus=0
+dirmode=""
+
+usage="\
+Usage: mkinstalldirs [-h] [--help] [-m mode] dir ..."
+
+# process command line arguments
+while test $# -gt 0 ; do
+ case $1 in
+ -h | --help | --h*) # -h for help
+ echo "$usage" 1>&2
+ exit 0
+ ;;
+ -m) # -m PERM arg
+ shift
+ test $# -eq 0 && { echo "$usage" 1>&2; exit 1; }
+ dirmode=$1
+ shift
+ ;;
+ --) # stop option processing
+ shift
+ break
+ ;;
+ -*) # unknown option
+ echo "$usage" 1>&2
+ exit 1
+ ;;
+ *) # first non-opt arg
+ break
+ ;;
+ esac
+done
+
+for file
+do
+ if test -d "$file"; then
+ shift
+ else
+ break
+ fi
+done
+
+case $# in
+ 0) exit 0 ;;
+esac
+
+case $dirmode in
+ '')
+ if mkdir -p -- . 2>/dev/null; then
+ echo "mkdir -p -- $*"
+ exec mkdir -p -- "$@"
+ fi
+ ;;
+ *)
+ if mkdir -m "$dirmode" -p -- . 2>/dev/null; then
+ echo "mkdir -m $dirmode -p -- $*"
+ exec mkdir -m "$dirmode" -p -- "$@"
+ fi
+ ;;
+esac
+
+for file
+do
+ set fnord `echo ":$file" | sed -ne 's/^:\//#/;s/^://;s/\// /g;s/^#/\//;p'`
+ shift
+
+ pathcomp=
+ for d
+ do
+ pathcomp="$pathcomp$d"
+ case $pathcomp in
+ -*) pathcomp=./$pathcomp ;;
+ esac
+
+ if test ! -d "$pathcomp"; then
+ echo "mkdir $pathcomp"
+
+ mkdir "$pathcomp" || lasterr=$?
+
+ if test ! -d "$pathcomp"; then
+ errstatus=$lasterr
+ else
+ if test ! -z "$dirmode"; then
+ echo "chmod $dirmode $pathcomp"
+ lasterr=""
+ chmod "$dirmode" "$pathcomp" || lasterr=$?
+
+ if test ! -z "$lasterr"; then
+ errstatus=$lasterr
+ fi
+ fi
+ fi
+ fi
+
+ pathcomp="$pathcomp/"
+ done
+done
+
+exit $errstatus
+
+# Local Variables:
+# mode: shell-script
+# sh-indentation: 2
+# End:
+# mkinstalldirs ends here
Property changes on: trunk/packages/rnahybrid/branches/upstream/current/mkinstalldirs
___________________________________________________________________
Name: svn:executable
+
Added: trunk/packages/rnahybrid/branches/upstream/current/src/Makefile.am
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/src/Makefile.am (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/src/Makefile.am 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,62 @@
+## Process this file with automake to produce Makefile.in
+
+bin_PROGRAMS = RNAhybrid RNAcalibrate RNAeffective
+
+RNAhybrid_SOURCES = \
+ rnahybrid.c\
+ hybrid_core.c\
+ hybrid_core.h\
+ energy.c\
+ energy.h\
+ input.c\
+ input.h\
+ fasta.c\
+ fasta.h\
+ globals.h\
+ minmax.h\
+ plot.c\
+ plot.h
+
+RNAcalibrate_SOURCES = \
+ rnacalibrate.c\
+ hybrid_core.c\
+ hybrid_core.h\
+ numerical.c\
+ numerical.h\
+ energy.c\
+ energy.h\
+ input.c\
+ input.h\
+ fasta.c\
+ fasta.h\
+ random.c\
+ random.h\
+ mt19937-1.c\
+ mt19937-1.h\
+ globals.h\
+ minmax.h\
+ plot.c\
+ plot.h
+
+RNAeffective_SOURCES = \
+ rnaeffective.c\
+ hybrid_core.c\
+ hybrid_core.h\
+ numerical.c\
+ numerical.h\
+ energy.c\
+ energy.h\
+ input.c\
+ input.h\
+ fasta.c\
+ fasta.h\
+ random.c\
+ random.h\
+ mt19937-1.c\
+ mt19937-1.h\
+ globals.h\
+ minmax.h\
+ plot.c\
+ plot.h
+
+INCLUDES = -I${includedir}
Added: trunk/packages/rnahybrid/branches/upstream/current/src/Makefile.in
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/src/Makefile.in (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/src/Makefile.in 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,481 @@
+# Makefile.in generated by automake 1.7.3 from Makefile.am.
+# @configure_input@
+
+# Copyright 1994, 1995, 1996, 1997, 1998, 1999, 2000, 2001, 2002, 2003
+# Free Software Foundation, Inc.
+# This Makefile.in is free software; the Free Software Foundation
+# gives unlimited permission to copy and/or distribute it,
+# with or without modifications, as long as this notice is preserved.
+
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY, to the extent permitted by law; without
+# even the implied warranty of MERCHANTABILITY or FITNESS FOR A
+# PARTICULAR PURPOSE.
+
+ at SET_MAKE@
+
+srcdir = @srcdir@
+top_srcdir = @top_srcdir@
+VPATH = @srcdir@
+pkgdatadir = $(datadir)/@PACKAGE@
+pkglibdir = $(libdir)/@PACKAGE@
+pkgincludedir = $(includedir)/@PACKAGE@
+top_builddir = ..
+
+am__cd = CDPATH="$${ZSH_VERSION+.}$(PATH_SEPARATOR)" && cd
+INSTALL = @INSTALL@
+install_sh_DATA = $(install_sh) -c -m 644
+install_sh_PROGRAM = $(install_sh) -c
+install_sh_SCRIPT = $(install_sh) -c
+INSTALL_HEADER = $(INSTALL_DATA)
+transform = $(program_transform_name)
+NORMAL_INSTALL = :
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+POST_INSTALL = :
+NORMAL_UNINSTALL = :
+PRE_UNINSTALL = :
+POST_UNINSTALL = :
+ACLOCAL = @ACLOCAL@
+AMDEP_FALSE = @AMDEP_FALSE@
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+INSTALL_DATA = @INSTALL_DATA@
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+LDFLAGS = @LDFLAGS@
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+LTLIBOBJS = @LTLIBOBJS@
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+localstatedir = @localstatedir@
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+oldincludedir = @oldincludedir@
+prefix = @prefix@
+program_transform_name = @program_transform_name@
+sbindir = @sbindir@
+sharedstatedir = @sharedstatedir@
+sysconfdir = @sysconfdir@
+target_alias = @target_alias@
+
+bin_PROGRAMS = RNAhybrid RNAcalibrate RNAeffective
+
+RNAhybrid_SOURCES = \
+ rnahybrid.c\
+ hybrid_core.c\
+ hybrid_core.h\
+ energy.c\
+ energy.h\
+ input.c\
+ input.h\
+ fasta.c\
+ fasta.h\
+ globals.h\
+ minmax.h\
+ plot.c\
+ plot.h
+
+
+RNAcalibrate_SOURCES = \
+ rnacalibrate.c\
+ hybrid_core.c\
+ hybrid_core.h\
+ numerical.c\
+ numerical.h\
+ energy.c\
+ energy.h\
+ input.c\
+ input.h\
+ fasta.c\
+ fasta.h\
+ random.c\
+ random.h\
+ mt19937-1.c\
+ mt19937-1.h\
+ globals.h\
+ minmax.h\
+ plot.c\
+ plot.h
+
+
+RNAeffective_SOURCES = \
+ rnaeffective.c\
+ hybrid_core.c\
+ hybrid_core.h\
+ numerical.c\
+ numerical.h\
+ energy.c\
+ energy.h\
+ input.c\
+ input.h\
+ fasta.c\
+ fasta.h\
+ random.c\
+ random.h\
+ mt19937-1.c\
+ mt19937-1.h\
+ globals.h\
+ minmax.h\
+ plot.c\
+ plot.h
+
+
+INCLUDES = -I${includedir}
+subdir = src
+mkinstalldirs = $(SHELL) $(top_srcdir)/mkinstalldirs
+CONFIG_HEADER = $(top_builddir)/config.h
+CONFIG_CLEAN_FILES =
+bin_PROGRAMS = RNAhybrid$(EXEEXT) RNAcalibrate$(EXEEXT) \
+ RNAeffective$(EXEEXT)
+PROGRAMS = $(bin_PROGRAMS)
+
+am_RNAcalibrate_OBJECTS = rnacalibrate.$(OBJEXT) hybrid_core.$(OBJEXT) \
+ numerical.$(OBJEXT) energy.$(OBJEXT) input.$(OBJEXT) \
+ fasta.$(OBJEXT) random.$(OBJEXT) mt19937-1.$(OBJEXT) \
+ plot.$(OBJEXT)
+RNAcalibrate_OBJECTS = $(am_RNAcalibrate_OBJECTS)
+RNAcalibrate_LDADD = $(LDADD)
+RNAcalibrate_DEPENDENCIES =
+RNAcalibrate_LDFLAGS =
+am_RNAeffective_OBJECTS = rnaeffective.$(OBJEXT) hybrid_core.$(OBJEXT) \
+ numerical.$(OBJEXT) energy.$(OBJEXT) input.$(OBJEXT) \
+ fasta.$(OBJEXT) random.$(OBJEXT) mt19937-1.$(OBJEXT) \
+ plot.$(OBJEXT)
+RNAeffective_OBJECTS = $(am_RNAeffective_OBJECTS)
+RNAeffective_LDADD = $(LDADD)
+RNAeffective_DEPENDENCIES =
+RNAeffective_LDFLAGS =
+am_RNAhybrid_OBJECTS = rnahybrid.$(OBJEXT) hybrid_core.$(OBJEXT) \
+ energy.$(OBJEXT) input.$(OBJEXT) fasta.$(OBJEXT) plot.$(OBJEXT)
+RNAhybrid_OBJECTS = $(am_RNAhybrid_OBJECTS)
+RNAhybrid_LDADD = $(LDADD)
+RNAhybrid_DEPENDENCIES =
+RNAhybrid_LDFLAGS =
+
+DEFAULT_INCLUDES = -I. -I$(srcdir) -I$(top_builddir)
+depcomp = $(SHELL) $(top_srcdir)/depcomp
+am__depfiles_maybe = depfiles
+ at AMDEP_TRUE@DEP_FILES = ./$(DEPDIR)/energy.Po ./$(DEPDIR)/fasta.Po \
+ at AMDEP_TRUE@ ./$(DEPDIR)/hybrid_core.Po ./$(DEPDIR)/input.Po \
+ at AMDEP_TRUE@ ./$(DEPDIR)/mt19937-1.Po ./$(DEPDIR)/numerical.Po \
+ at AMDEP_TRUE@ ./$(DEPDIR)/plot.Po ./$(DEPDIR)/random.Po \
+ at AMDEP_TRUE@ ./$(DEPDIR)/rnacalibrate.Po \
+ at AMDEP_TRUE@ ./$(DEPDIR)/rnaeffective.Po \
+ at AMDEP_TRUE@ ./$(DEPDIR)/rnahybrid.Po
+COMPILE = $(CC) $(DEFS) $(DEFAULT_INCLUDES) $(INCLUDES) $(AM_CPPFLAGS) \
+ $(CPPFLAGS) $(AM_CFLAGS) $(CFLAGS)
+CCLD = $(CC)
+LINK = $(CCLD) $(AM_CFLAGS) $(CFLAGS) $(AM_LDFLAGS) $(LDFLAGS) -o $@
+DIST_SOURCES = $(RNAcalibrate_SOURCES) $(RNAeffective_SOURCES) \
+ $(RNAhybrid_SOURCES)
+DIST_COMMON = Makefile.am Makefile.in
+SOURCES = $(RNAcalibrate_SOURCES) $(RNAeffective_SOURCES) $(RNAhybrid_SOURCES)
+
+all: all-am
+
+.SUFFIXES:
+.SUFFIXES: .c .o .obj
+$(srcdir)/Makefile.in: Makefile.am $(top_srcdir)/configure.in $(ACLOCAL_M4)
+ cd $(top_srcdir) && \
+ $(AUTOMAKE) --gnu src/Makefile
+Makefile: $(srcdir)/Makefile.in $(top_builddir)/config.status
+ cd $(top_builddir) && $(SHELL) ./config.status $(subdir)/$@ $(am__depfiles_maybe)
+binPROGRAMS_INSTALL = $(INSTALL_PROGRAM)
+install-binPROGRAMS: $(bin_PROGRAMS)
+ @$(NORMAL_INSTALL)
+ $(mkinstalldirs) $(DESTDIR)$(bindir)
+ @list='$(bin_PROGRAMS)'; for p in $$list; do \
+ p1=`echo $$p|sed 's/$(EXEEXT)$$//'`; \
+ if test -f $$p \
+ ; then \
+ f=`echo "$$p1" | sed 's,^.*/,,;$(transform);s/$$/$(EXEEXT)/'`; \
+ echo " $(INSTALL_PROGRAM_ENV) $(binPROGRAMS_INSTALL) $$p $(DESTDIR)$(bindir)/$$f"; \
+ $(INSTALL_PROGRAM_ENV) $(binPROGRAMS_INSTALL) $$p $(DESTDIR)$(bindir)/$$f || exit 1; \
+ else :; fi; \
+ done
+
+uninstall-binPROGRAMS:
+ @$(NORMAL_UNINSTALL)
+ @list='$(bin_PROGRAMS)'; for p in $$list; do \
+ f=`echo "$$p" | sed 's,^.*/,,;s/$(EXEEXT)$$//;$(transform);s/$$/$(EXEEXT)/'`; \
+ echo " rm -f $(DESTDIR)$(bindir)/$$f"; \
+ rm -f $(DESTDIR)$(bindir)/$$f; \
+ done
+
+clean-binPROGRAMS:
+ -test -z "$(bin_PROGRAMS)" || rm -f $(bin_PROGRAMS)
+RNAcalibrate$(EXEEXT): $(RNAcalibrate_OBJECTS) $(RNAcalibrate_DEPENDENCIES)
+ @rm -f RNAcalibrate$(EXEEXT)
+ $(LINK) $(RNAcalibrate_LDFLAGS) $(RNAcalibrate_OBJECTS) $(RNAcalibrate_LDADD) $(LIBS)
+RNAeffective$(EXEEXT): $(RNAeffective_OBJECTS) $(RNAeffective_DEPENDENCIES)
+ @rm -f RNAeffective$(EXEEXT)
+ $(LINK) $(RNAeffective_LDFLAGS) $(RNAeffective_OBJECTS) $(RNAeffective_LDADD) $(LIBS)
+RNAhybrid$(EXEEXT): $(RNAhybrid_OBJECTS) $(RNAhybrid_DEPENDENCIES)
+ @rm -f RNAhybrid$(EXEEXT)
+ $(LINK) $(RNAhybrid_LDFLAGS) $(RNAhybrid_OBJECTS) $(RNAhybrid_LDADD) $(LIBS)
+
+mostlyclean-compile:
+ -rm -f *.$(OBJEXT) core *.core
+
+distclean-compile:
+ -rm -f *.tab.c
+
+ at AMDEP_TRUE@@am__include@ @am__quote at ./$(DEPDIR)/energy.Po at am__quote@
+ at AMDEP_TRUE@@am__include@ @am__quote at ./$(DEPDIR)/fasta.Po at am__quote@
+ at AMDEP_TRUE@@am__include@ @am__quote at ./$(DEPDIR)/hybrid_core.Po at am__quote@
+ at AMDEP_TRUE@@am__include@ @am__quote at ./$(DEPDIR)/input.Po at am__quote@
+ at AMDEP_TRUE@@am__include@ @am__quote at ./$(DEPDIR)/mt19937-1.Po at am__quote@
+ at AMDEP_TRUE@@am__include@ @am__quote at ./$(DEPDIR)/numerical.Po at am__quote@
+ at AMDEP_TRUE@@am__include@ @am__quote at ./$(DEPDIR)/plot.Po at am__quote@
+ at AMDEP_TRUE@@am__include@ @am__quote at ./$(DEPDIR)/random.Po at am__quote@
+ at AMDEP_TRUE@@am__include@ @am__quote at ./$(DEPDIR)/rnacalibrate.Po at am__quote@
+ at AMDEP_TRUE@@am__include@ @am__quote at ./$(DEPDIR)/rnaeffective.Po at am__quote@
+ at AMDEP_TRUE@@am__include@ @am__quote at ./$(DEPDIR)/rnahybrid.Po at am__quote@
+
+distclean-depend:
+ -rm -rf ./$(DEPDIR)
+
+.c.o:
+ at am__fastdepCC_TRUE@ if $(COMPILE) -MT $@ -MD -MP -MF "$(DEPDIR)/$*.Tpo" \
+ at am__fastdepCC_TRUE@ -c -o $@ `test -f '$<' || echo '$(srcdir)/'`$<; \
+ at am__fastdepCC_TRUE@ then mv "$(DEPDIR)/$*.Tpo" "$(DEPDIR)/$*.Po"; \
+ at am__fastdepCC_TRUE@ else rm -f "$(DEPDIR)/$*.Tpo"; exit 1; \
+ at am__fastdepCC_TRUE@ fi
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+ at am__fastdepCC_FALSE@ $(COMPILE) -c `test -f '$<' || echo '$(srcdir)/'`$<
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+.c.obj:
+ at am__fastdepCC_TRUE@ if $(COMPILE) -MT $@ -MD -MP -MF "$(DEPDIR)/$*.Tpo" \
+ at am__fastdepCC_TRUE@ -c -o $@ `if test -f '$<'; then $(CYGPATH_W) '$<'; else $(CYGPATH_W) '$(srcdir)/$<'; fi`; \
+ at am__fastdepCC_TRUE@ then mv "$(DEPDIR)/$*.Tpo" "$(DEPDIR)/$*.Po"; \
+ at am__fastdepCC_TRUE@ else rm -f "$(DEPDIR)/$*.Tpo"; exit 1; \
+ at am__fastdepCC_TRUE@ fi
+ at AMDEP_TRUE@@am__fastdepCC_FALSE@ source='$<' object='$@' libtool=no @AMDEPBACKSLASH@
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+uninstall-info-am:
+
+ETAGS = etags
+ETAGSFLAGS =
+
+CTAGS = ctags
+CTAGSFLAGS =
+
+tags: TAGS
+
+ID: $(HEADERS) $(SOURCES) $(LISP) $(TAGS_FILES)
+ list='$(SOURCES) $(HEADERS) $(LISP) $(TAGS_FILES)'; \
+ unique=`for i in $$list; do \
+ if test -f "$$i"; then echo $$i; else echo $(srcdir)/$$i; fi; \
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+ $(AWK) ' { files[$$0] = 1; } \
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+ mkid -fID $$unique
+
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+ done | \
+ $(AWK) ' { files[$$0] = 1; } \
+ END { for (i in files) print i; }'`; \
+ test -z "$(ETAGS_ARGS)$$tags$$unique" \
+ || $(ETAGS) $(ETAGSFLAGS) $(AM_ETAGSFLAGS) $(ETAGS_ARGS) \
+ $$tags $$unique
+
+ctags: CTAGS
+CTAGS: $(HEADERS) $(SOURCES) $(TAGS_DEPENDENCIES) \
+ $(TAGS_FILES) $(LISP)
+ tags=; \
+ here=`pwd`; \
+ list='$(SOURCES) $(HEADERS) $(LISP) $(TAGS_FILES)'; \
+ unique=`for i in $$list; do \
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+ done | \
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+ test -z "$(CTAGS_ARGS)$$tags$$unique" \
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+
+GTAGS:
+ here=`$(am__cd) $(top_builddir) && pwd` \
+ && cd $(top_srcdir) \
+ && gtags -i $(GTAGS_ARGS) $$here
+
+distclean-tags:
+ -rm -f TAGS ID GTAGS GRTAGS GSYMS GPATH tags
+DISTFILES = $(DIST_COMMON) $(DIST_SOURCES) $(TEXINFOS) $(EXTRA_DIST)
+
+top_distdir = ..
+distdir = $(top_distdir)/$(PACKAGE)-$(VERSION)
+
+distdir: $(DISTFILES)
+ @srcdirstrip=`echo "$(srcdir)" | sed 's|.|.|g'`; \
+ topsrcdirstrip=`echo "$(top_srcdir)" | sed 's|.|.|g'`; \
+ list='$(DISTFILES)'; for file in $$list; do \
+ case $$file in \
+ $(srcdir)/*) file=`echo "$$file" | sed "s|^$$srcdirstrip/||"`;; \
+ $(top_srcdir)/*) file=`echo "$$file" | sed "s|^$$topsrcdirstrip/|$(top_builddir)/|"`;; \
+ esac; \
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+ if test "$$dir" != "$$file" && test "$$dir" != "."; then \
+ dir="/$$dir"; \
+ $(mkinstalldirs) "$(distdir)$$dir"; \
+ else \
+ dir=''; \
+ fi; \
+ if test -d $$d/$$file; then \
+ if test -d $(srcdir)/$$file && test $$d != $(srcdir); then \
+ cp -pR $(srcdir)/$$file $(distdir)$$dir || exit 1; \
+ fi; \
+ cp -pR $$d/$$file $(distdir)$$dir || exit 1; \
+ else \
+ test -f $(distdir)/$$file \
+ || cp -p $$d/$$file $(distdir)/$$file \
+ || exit 1; \
+ fi; \
+ done
+check-am: all-am
+check: check-am
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+
+installdirs:
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+
+install: install-am
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+install-data: install-data-am
+uninstall: uninstall-am
+
+install-am: all-am
+ @$(MAKE) $(AM_MAKEFLAGS) install-exec-am install-data-am
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+installcheck: installcheck-am
+install-strip:
+ $(MAKE) $(AM_MAKEFLAGS) INSTALL_PROGRAM="$(INSTALL_STRIP_PROGRAM)" \
+ INSTALL_STRIP_FLAG=-s \
+ `test -z '$(STRIP)' || \
+ echo "INSTALL_PROGRAM_ENV=STRIPPROG='$(STRIP)'"` install
+mostlyclean-generic:
+
+clean-generic:
+
+distclean-generic:
+ -rm -f Makefile $(CONFIG_CLEAN_FILES)
+
+maintainer-clean-generic:
+ @echo "This command is intended for maintainers to use"
+ @echo "it deletes files that may require special tools to rebuild."
+clean: clean-am
+
+clean-am: clean-binPROGRAMS clean-generic mostlyclean-am
+
+distclean: distclean-am
+
+distclean-am: clean-am distclean-compile distclean-depend \
+ distclean-generic distclean-tags
+
+dvi: dvi-am
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+dvi-am:
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+info: info-am
+
+info-am:
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+install-data-am:
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+install-exec-am: install-binPROGRAMS
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+install-info: install-info-am
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+install-man:
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+maintainer-clean-am: distclean-am maintainer-clean-generic
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+mostlyclean-am: mostlyclean-compile mostlyclean-generic
+
+pdf: pdf-am
+
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+ps-am:
+
+uninstall-am: uninstall-binPROGRAMS uninstall-info-am
+
+.PHONY: CTAGS GTAGS all all-am check check-am clean clean-binPROGRAMS \
+ clean-generic ctags distclean distclean-compile \
+ distclean-depend distclean-generic distclean-tags distdir dvi \
+ dvi-am info info-am install install-am install-binPROGRAMS \
+ install-data install-data-am install-exec install-exec-am \
+ install-info install-info-am install-man install-strip \
+ installcheck installcheck-am installdirs maintainer-clean \
+ maintainer-clean-generic mostlyclean mostlyclean-compile \
+ mostlyclean-generic pdf pdf-am ps ps-am tags uninstall \
+ uninstall-am uninstall-binPROGRAMS uninstall-info-am
+
+# Tell versions [3.59,3.63) of GNU make to not export all variables.
+# Otherwise a system limit (for SysV at least) may be exceeded.
+.NOEXPORT:
Added: trunk/packages/rnahybrid/branches/upstream/current/src/energy.c
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/src/energy.c (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/src/energy.c 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,12783 @@
+/* Copyright (C) 2004 Marc Rehmsmeier, Peter Steffen, Matthias Hoechsmann */
+
+/* This program is free software; you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation; either version 2 of the License, or (at your option) any later version. */
+
+/* This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details. */
+
+/* You should have received a copy of the GNU General Public License along with this program; if not, write to the Free Software Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA */
+
+#include "energy.h"
+
+void init_constants()
+{
+ e = 2.718281828459;
+ t = 273.15;
+ temp = t + 37.0;
+ r = 8.3143;
+
+ wkn = 0.83;
+
+ npp = 0.2;
+ pbp = 0.1 * wkn;
+
+ mloop_close = 4.6;
+ free_base_penalty = 0.4;
+ helix_penalty = 0.1;
+}
+
+
+#define compl(I,J) canPair[I][J]
+
+
+double sr_energy(int i, int j){
+ return(stack_dg_ar[inpx(i)][inpx(i+1)][inpy(j+1)][inpy(j)]);
+}
+
+
+double dr_energy(int i, int j){
+ return(dr_dangle_dg_ar[inpx(i)][inpy(j)][inpy(j-1)]);
+}
+
+double dli_energy(int i, int j){
+ return(dr_dangle_dg_ar[inpy(j)][inpx(i)][inpx(i+1)]);
+}
+
+double dl_energy(int i, int j){
+ return(dl_dangle_dg_ar[inpx(i-1)][inpx(i)][inpy(j)]);
+}
+
+double dri_energy(int i, int j){
+ return(dl_dangle_dg_ar[inpy(j+1)][inpy(j)][inpx(i)]);
+}
+
+
+double dangles (int i, int j, int i2, int j2, int k, int l, int k2,int l2) {
+ return((dli_energy(j,k+1)+dri_energy(j2,k2+1))*wkn);
+}
+
+double sspenalty(int a){
+ return(npp*a);
+}
+
+double log_interp(int size){
+ return(1.079*log(((double)size)/30.0));
+}
+
+
+double hl_ent(int size){
+ return (size<=30 ? hl_ent_ar[size] : hl_ent_ar[30] + log_interp(size));
+}
+
+double bl_ent(int size){
+ return (size<=30 ? bl_ent_ar[size] : bl_ent_ar[30] + log_interp(size));
+}
+
+#define il_ent(size) ((size)<=30 ? il_ent_ar[(size)] : il_ent_ar[30] + log_interp((size)))
+
+int lengthOf(int i, int j){
+ return(j-i);
+}
+
+
+void init_il_asym_ar()
+{
+ int i, j;
+
+ for (i=1; i<=15; i++)
+ for (j=1; j<=15; j++)
+ il_asym_ar[i][j] = min(3.0, abs(i-j)*0.3);
+}
+
+
+/* double il_asym (int sl, int sr){ */
+/* return(min(3.0, abs(sl-sr)*0.3)); */
+/* } */
+
+
+double bl_stacking (int t, int b, int i, int j){
+ if ((t==0) && (b==1)) return(stack_dg_ar[inpx(i)][inpx(i+1)][inpy(j+2)][inpy(j)]);
+ else if ((t==1) && (b==0)) return(stack_dg_ar[inpx(i)][inpx(i+2)][inpy(j+1)][inpy(j)]);
+ else return(0);
+}
+
+
+
+
+double int_special(int i, int j, int t, int b)
+{
+ if ((t==1) && (b==1)) return(int11_ar[inpx(i)][inpy(j)][inpx(i+1)][inpy(j+1)][inpx(i+2)][inpy(j+2)]);
+ else if ((t==1) && (b==2)) return(int21_ar[inpx(i)][inpy(j)][inpx(i+1)][inpy(j+1)][inpy(j+2)][inpx(i+2)][inpy(j+3)]);
+ else if ((t==2) && (b==1)) return(int21_ar[inpy(j+2)][inpx(i+3)][inpy(j+1)][inpx(i+2)][inpx(i+1)][inpy(j)][inpx(i)]);
+ else if ((t==2) && (b==2)) return(int22_ar[inpx(i)][inpy(j)][inpx(i+1)][inpx(i+2)][inpy(j+1)][inpy(j+2)][inpx(i+3)][inpy(j+3)]);
+}
+
+
+double do_il_special(int i, int j, int k, int l, int u, int v, double e)
+{
+ return(e+int_special(i,j,l-k,v-u));
+}
+
+
+/* double do_il(int i, int j, int k, int l, int u, int v, double e){ */
+/* return(e+ il_stack_close (l+1,v+1) + il_ent (l-k+v-u) + il_asym (l-k,v-u)); */
+/* } */
+
+
+void init_hl_ent_ar()
+{
+
+ int i;
+ for(i=0;i<=2;i++) hl_ent_ar[i] = 0;
+
+ hl_ent_ar[ 3] = 5.7000;
+ hl_ent_ar[ 4] = 5.6000;
+ hl_ent_ar[ 5] = 5.6000;
+ hl_ent_ar[ 6] = 5.4000;
+ hl_ent_ar[ 7] = 5.9000;
+ hl_ent_ar[ 8] = 5.6000;
+ hl_ent_ar[ 9] = 6.4000;
+ hl_ent_ar[10] = 6.5000;
+ hl_ent_ar[11] = 6.6000;
+ hl_ent_ar[12] = 6.7000;
+ hl_ent_ar[13] = 6.7800;
+ hl_ent_ar[14] = 6.8600;
+ hl_ent_ar[15] = 6.9400;
+ hl_ent_ar[16] = 7.0100;
+ hl_ent_ar[17] = 7.0700;
+ hl_ent_ar[18] = 7.1300;
+ hl_ent_ar[19] = 7.1900;
+ hl_ent_ar[20] = 7.2500;
+ hl_ent_ar[21] = 7.3000;
+ hl_ent_ar[22] = 7.3500;
+ hl_ent_ar[23] = 7.4000;
+ hl_ent_ar[24] = 7.4400;
+ hl_ent_ar[25] = 7.4900;
+ hl_ent_ar[26] = 7.5300;
+ hl_ent_ar[27] = 7.5700;
+ hl_ent_ar[28] = 7.6100;
+ hl_ent_ar[29] = 7.6500;
+ hl_ent_ar[30] = 7.6900;
+}
+
+void init_stack_dg_ar()
+{
+
+ int i,j,k,l;
+ for(i=0;i<ALPHASIZE;i++) for(j=0;j<ALPHASIZE;j++) for(k=0;k<ALPHASIZE;k++) for(l=0;l<ALPHASIZE;l++) stack_dg_ar[i][j][k][l] = 0;
+
+ stack_dg_ar[A][A][U][U] = -0.900;
+ stack_dg_ar[A][C][G][U] = -2.200;
+ stack_dg_ar[A][G][C][U] = -2.100;
+ stack_dg_ar[A][G][U][U] = -0.600;
+ stack_dg_ar[A][U][A][U] = -1.100;
+ stack_dg_ar[A][U][G][U] = -1.400;
+ stack_dg_ar[C][A][U][G] = -2.100;
+ stack_dg_ar[C][C][G][G] = -3.300;
+ stack_dg_ar[C][G][C][G] = -2.400;
+ stack_dg_ar[C][G][U][G] = -1.400;
+ stack_dg_ar[C][U][A][G] = -2.100;
+ stack_dg_ar[C][U][G][G] = -2.100;
+ stack_dg_ar[G][A][U][C] = -2.400;
+ stack_dg_ar[G][A][U][U] = -1.300;
+ stack_dg_ar[G][C][G][C] = -3.400;
+ stack_dg_ar[G][C][G][U] = -2.500;
+ stack_dg_ar[G][G][C][C] = -3.300;
+ stack_dg_ar[G][G][C][U] = -2.100;
+ stack_dg_ar[G][G][U][C] = -1.500;
+ stack_dg_ar[G][G][U][U] = -0.500;
+ stack_dg_ar[G][U][A][C] = -2.200;
+ stack_dg_ar[G][U][A][U] = -1.400;
+ stack_dg_ar[G][U][G][C] = -2.500;
+ stack_dg_ar[G][U][G][U] = 1.300;
+ stack_dg_ar[U][A][U][A] = -1.300;
+ stack_dg_ar[U][A][U][G] = -1.000;
+ stack_dg_ar[U][C][G][A] = -2.400;
+ stack_dg_ar[U][C][G][G] = -1.500;
+ stack_dg_ar[U][G][C][A] = -2.100;
+ stack_dg_ar[U][G][C][G] = -1.400;
+ stack_dg_ar[U][G][U][A] = -1.000;
+ stack_dg_ar[U][G][U][G] = 0.300;
+ stack_dg_ar[U][U][A][A] = -0.900;
+ stack_dg_ar[U][U][A][G] = -0.600;
+ stack_dg_ar[U][U][G][A] = -1.300;
+ stack_dg_ar[U][U][G][G] = -0.500;
+}
+
+void init_tstackh_dg_ar()
+{
+
+ int i,j,k,l;
+ for(i=0;i<ALPHASIZE;i++) for(j=0;j<ALPHASIZE;j++) for(k=0;k<ALPHASIZE;k++) for(l=0;l<ALPHASIZE;l++) tstackh_dg_ar[i][j][k][l] = 0;
+
+ tstackh_dg_ar[A][A][A][U] = -0.300;
+ tstackh_dg_ar[A][A][C][U] = -0.500;
+ tstackh_dg_ar[A][A][G][U] = -0.300;
+ tstackh_dg_ar[A][A][U][U] = -0.300;
+ tstackh_dg_ar[A][C][A][U] = -0.100;
+ tstackh_dg_ar[A][C][C][U] = -0.200;
+ tstackh_dg_ar[A][C][G][U] = -1.500;
+ tstackh_dg_ar[A][C][U][U] = -0.200;
+ tstackh_dg_ar[A][G][A][U] = -1.100;
+ tstackh_dg_ar[A][G][C][U] = -1.200;
+ tstackh_dg_ar[A][G][G][U] = -0.200;
+ tstackh_dg_ar[A][G][U][U] = 0.200;
+ tstackh_dg_ar[A][U][A][U] = -0.300;
+ tstackh_dg_ar[A][U][C][U] = -0.300;
+ tstackh_dg_ar[A][U][G][U] = -0.600;
+ tstackh_dg_ar[A][U][U][U] = -1.100;
+ tstackh_dg_ar[C][A][A][G] = -1.500;
+ tstackh_dg_ar[C][A][C][G] = -1.500;
+ tstackh_dg_ar[C][A][G][G] = -1.400;
+ tstackh_dg_ar[C][A][U][G] = -1.800;
+ tstackh_dg_ar[C][C][A][G] = -1.000;
+ tstackh_dg_ar[C][C][C][G] = -0.900;
+ tstackh_dg_ar[C][C][G][G] = -2.900;
+ tstackh_dg_ar[C][C][U][G] = -0.800;
+ tstackh_dg_ar[C][G][A][G] = -2.200;
+ tstackh_dg_ar[C][G][C][G] = -2.000;
+ tstackh_dg_ar[C][G][G][G] = -1.600;
+ tstackh_dg_ar[C][G][U][G] = -1.100;
+ tstackh_dg_ar[C][U][A][G] = -1.700;
+ tstackh_dg_ar[C][U][C][G] = -1.400;
+ tstackh_dg_ar[C][U][G][G] = -1.800;
+ tstackh_dg_ar[C][U][U][G] = -2.000;
+ tstackh_dg_ar[G][A][A][C] = -1.100;
+ tstackh_dg_ar[G][A][A][U] = 0.200;
+ tstackh_dg_ar[G][A][C][C] = -1.500;
+ tstackh_dg_ar[G][A][C][U] = -0.500;
+ tstackh_dg_ar[G][A][G][C] = -1.300;
+ tstackh_dg_ar[G][A][G][U] = -0.300;
+ tstackh_dg_ar[G][A][U][C] = -2.100;
+ tstackh_dg_ar[G][A][U][U] = -0.300;
+ tstackh_dg_ar[G][C][A][C] = -1.100;
+ tstackh_dg_ar[G][C][A][U] = -0.100;
+ tstackh_dg_ar[G][C][C][C] = -0.700;
+ tstackh_dg_ar[G][C][C][U] = -0.200;
+ tstackh_dg_ar[G][C][G][C] = -2.400;
+ tstackh_dg_ar[G][C][G][U] = -1.500;
+ tstackh_dg_ar[G][C][U][C] = -0.500;
+ tstackh_dg_ar[G][C][U][U] = -0.200;
+ tstackh_dg_ar[G][G][A][C] = -2.400;
+ tstackh_dg_ar[G][G][A][U] = -0.900;
+ tstackh_dg_ar[G][G][C][C] = -2.900;
+ tstackh_dg_ar[G][G][C][U] = -1.100;
+ tstackh_dg_ar[G][G][G][C] = -1.400;
+ tstackh_dg_ar[G][G][G][U] = -0.300;
+ tstackh_dg_ar[G][G][U][C] = -1.200;
+ tstackh_dg_ar[G][G][U][U] = 0.000;
+ tstackh_dg_ar[G][U][A][C] = -1.900;
+ tstackh_dg_ar[G][U][A][U] = -0.300;
+ tstackh_dg_ar[G][U][C][C] = -1.000;
+ tstackh_dg_ar[G][U][C][U] = -0.300;
+ tstackh_dg_ar[G][U][G][C] = -2.200;
+ tstackh_dg_ar[G][U][G][U] = -0.400;
+ tstackh_dg_ar[G][U][U][C] = -1.500;
+ tstackh_dg_ar[G][U][U][U] = -1.100;
+ tstackh_dg_ar[U][A][A][A] = -0.500;
+ tstackh_dg_ar[U][A][A][G] = -0.500;
+ tstackh_dg_ar[U][A][C][A] = -0.300;
+ tstackh_dg_ar[U][A][C][G] = -0.300;
+ tstackh_dg_ar[U][A][G][A] = -0.600;
+ tstackh_dg_ar[U][A][G][G] = -0.600;
+ tstackh_dg_ar[U][A][U][A] = -0.500;
+ tstackh_dg_ar[U][A][U][G] = -0.500;
+ tstackh_dg_ar[U][C][A][A] = -0.200;
+ tstackh_dg_ar[U][C][A][G] = -0.200;
+ tstackh_dg_ar[U][C][C][A] = -0.100;
+ tstackh_dg_ar[U][C][C][G] = -0.100;
+ tstackh_dg_ar[U][C][G][A] = -1.200;
+ tstackh_dg_ar[U][C][G][G] = -1.700;
+ tstackh_dg_ar[U][C][U][A] = 0.000;
+ tstackh_dg_ar[U][C][U][G] = 0.000;
+ tstackh_dg_ar[U][G][A][A] = -1.400;
+ tstackh_dg_ar[U][G][A][G] = -0.800;
+ tstackh_dg_ar[U][G][C][A] = -1.200;
+ tstackh_dg_ar[U][G][C][G] = -1.200;
+ tstackh_dg_ar[U][G][G][A] = -0.700;
+ tstackh_dg_ar[U][G][G][G] = -0.300;
+ tstackh_dg_ar[U][G][U][A] = -0.200;
+ tstackh_dg_ar[U][G][U][G] = -0.700;
+ tstackh_dg_ar[U][U][A][A] = -0.300;
+ tstackh_dg_ar[U][U][A][G] = -0.600;
+ tstackh_dg_ar[U][U][C][A] = -0.100;
+ tstackh_dg_ar[U][U][C][G] = -0.100;
+ tstackh_dg_ar[U][U][G][A] = -0.500;
+ tstackh_dg_ar[U][U][G][G] = -0.600;
+ tstackh_dg_ar[U][U][U][A] = -0.800;
+ tstackh_dg_ar[U][U][U][G] = -0.800;
+
+}
+
+void init_hl_tetra_ar()
+{
+ int k1,k2,k3,k4,k5,k6;
+
+ for (k1=0;k1<ALPHASIZE;k1++)
+ for (k2=0;k2<ALPHASIZE;k2++)
+ for (k3=0;k3<ALPHASIZE;k3++)
+ for (k4=0;k4<ALPHASIZE;k4++)
+ for (k5=0;k5<ALPHASIZE;k5++)
+ for (k6=0;k6<ALPHASIZE;k6++)
+ hl_tetra_ar[k1][k2][k3][k4][k5][k6]=0.0;
+
+ hl_tetra_ar[G][G][G][G][A][C] = -3.000;
+ hl_tetra_ar[G][G][U][G][A][C] = -3.000;
+ hl_tetra_ar[C][G][A][A][A][G] = -3.000;
+ hl_tetra_ar[G][G][A][G][A][C] = -3.000;
+ hl_tetra_ar[C][G][C][A][A][G] = -3.000;
+ hl_tetra_ar[G][G][A][A][A][C] = -3.000;
+ hl_tetra_ar[C][G][G][A][A][G] = -3.000;
+ hl_tetra_ar[C][U][U][C][G][G] = -3.000;
+ hl_tetra_ar[C][G][U][G][A][G] = -3.000;
+ hl_tetra_ar[C][G][A][A][G][G] = -2.500;
+ hl_tetra_ar[C][U][A][C][G][G] = -2.500;
+ hl_tetra_ar[G][G][C][A][A][C] = -2.500;
+ hl_tetra_ar[C][G][C][G][A][G] = -2.500;
+ hl_tetra_ar[U][G][A][G][A][G] = -2.500;
+ hl_tetra_ar[C][G][A][G][A][G] = -2.000;
+ hl_tetra_ar[A][G][A][A][A][U] = -2.000;
+ hl_tetra_ar[C][G][U][A][A][G] = -2.000;
+ hl_tetra_ar[C][U][A][A][C][G] = -2.000;
+ hl_tetra_ar[U][G][A][A][A][G] = -2.000;
+ hl_tetra_ar[G][G][A][A][G][C] = -1.500;
+ hl_tetra_ar[G][G][G][A][A][C] = -1.500;
+ hl_tetra_ar[U][G][A][A][A][A] = -1.500;
+ hl_tetra_ar[A][G][C][A][A][U] = -1.500;
+ hl_tetra_ar[A][G][U][A][A][U] = -1.500;
+ hl_tetra_ar[C][G][G][G][A][G] = -1.500;
+ hl_tetra_ar[A][G][U][G][A][U] = -1.500;
+ hl_tetra_ar[G][G][C][G][A][C] = -1.500;
+ hl_tetra_ar[G][G][G][A][G][C] = -1.500;
+ hl_tetra_ar[G][U][G][A][A][C] = -1.500;
+ hl_tetra_ar[U][G][G][A][A][A] = -1.500;
+
+}
+
+void init_bl_ent_ar()
+{
+
+ bl_ent_ar[ 0] = 0.0;
+ bl_ent_ar[ 1] = 3.8000;
+ bl_ent_ar[ 2] = 2.8000;
+ bl_ent_ar[ 3] = 3.2000;
+ bl_ent_ar[ 4] = 3.6000;
+ bl_ent_ar[ 5] = 4.0000;
+ bl_ent_ar[ 6] = 4.4000;
+ bl_ent_ar[ 7] = 4.5900;
+ bl_ent_ar[ 8] = 4.7000;
+ bl_ent_ar[ 9] = 4.8000;
+ bl_ent_ar[10] = 4.9000;
+ bl_ent_ar[11] = 5.0000;
+ bl_ent_ar[12] = 5.1000;
+ bl_ent_ar[13] = 5.1900;
+ bl_ent_ar[14] = 5.2700;
+ bl_ent_ar[15] = 5.3400;
+ bl_ent_ar[16] = 5.4100;
+ bl_ent_ar[17] = 5.4800;
+ bl_ent_ar[18] = 5.5400;
+ bl_ent_ar[19] = 5.6000;
+ bl_ent_ar[20] = 5.6500;
+ bl_ent_ar[21] = 5.7100;
+ bl_ent_ar[22] = 5.7600;
+ bl_ent_ar[23] = 5.8000;
+ bl_ent_ar[24] = 5.8500;
+ bl_ent_ar[25] = 5.8900;
+ bl_ent_ar[26] = 5.9400;
+ bl_ent_ar[27] = 5.9800;
+ bl_ent_ar[28] = 6.0200;
+ bl_ent_ar[29] = 6.0500;
+ bl_ent_ar[30] = 6.0900;
+
+}
+
+void init_il_ent_ar()
+{
+
+ il_ent_ar[ 0] = 0.0;
+ il_ent_ar[ 1] = 0.0;
+ il_ent_ar[ 2] = 4.1000;
+ il_ent_ar[ 3] = 5.1000;
+ il_ent_ar[ 4] = 1.7000;
+ il_ent_ar[ 5] = 1.8000;
+ il_ent_ar[ 6] = 2.0000;
+ il_ent_ar[ 7] = 2.2000;
+ il_ent_ar[ 8] = 2.3000;
+ il_ent_ar[ 9] = 2.4000;
+ il_ent_ar[10] = 2.5000;
+ il_ent_ar[11] = 2.6000;
+ il_ent_ar[12] = 2.7000;
+ il_ent_ar[13] = 2.7800;
+ il_ent_ar[14] = 2.8600;
+ il_ent_ar[15] = 2.9400;
+ il_ent_ar[16] = 3.0100;
+ il_ent_ar[17] = 3.0700;
+ il_ent_ar[18] = 3.1300;
+ il_ent_ar[19] = 3.1900;
+ il_ent_ar[20] = 3.2500;
+ il_ent_ar[21] = 3.3000;
+ il_ent_ar[22] = 3.3500;
+ il_ent_ar[23] = 3.4000;
+ il_ent_ar[24] = 3.4500;
+ il_ent_ar[25] = 3.4900;
+ il_ent_ar[26] = 3.5300;
+ il_ent_ar[27] = 3.5700;
+ il_ent_ar[28] = 3.6100;
+ il_ent_ar[29] = 3.6500;
+ il_ent_ar[30] = 3.6900;
+
+
+
+}
+
+void init_tstacki_dg_ar()
+{
+
+ int i,j,k,l;
+ for(i=0;i<ALPHASIZE;i++) for(j=0;j<ALPHASIZE;j++) for(k=0;k<ALPHASIZE;k++) for(l=0;l<ALPHASIZE;l++) tstacki_dg_ar[i][j][k][l] = 0;
+
+ tstacki_dg_ar[A][A][A][U] = 0.700;
+ tstacki_dg_ar[A][A][C][U] = 0.700;
+ tstacki_dg_ar[A][A][G][U] = -0.400;
+ tstacki_dg_ar[A][A][U][U] = 0.700;
+ tstacki_dg_ar[A][C][A][U] = 0.700;
+ tstacki_dg_ar[A][C][C][U] = 0.700;
+ tstacki_dg_ar[A][C][G][U] = 0.700;
+ tstacki_dg_ar[A][C][U][U] = 0.700;
+ tstacki_dg_ar[A][G][A][U] = -0.400;
+ tstacki_dg_ar[A][G][C][U] = 0.700;
+ tstacki_dg_ar[A][G][G][U] = 0.700;
+ tstacki_dg_ar[A][G][U][U] = 0.700;
+ tstacki_dg_ar[A][U][A][U] = 0.700;
+ tstacki_dg_ar[A][U][C][U] = 0.700;
+ tstacki_dg_ar[A][U][G][U] = 0.700;
+ tstacki_dg_ar[A][U][U][U] = 0.000;
+ tstacki_dg_ar[C][A][A][G] = 0.000;
+ tstacki_dg_ar[C][A][C][G] = 0.000;
+ tstacki_dg_ar[C][A][G][G] = -1.100;
+ tstacki_dg_ar[C][A][U][G] = 0.000;
+ tstacki_dg_ar[C][C][A][G] = 0.000;
+ tstacki_dg_ar[C][C][C][G] = 0.000;
+ tstacki_dg_ar[C][C][G][G] = 0.000;
+ tstacki_dg_ar[C][C][U][G] = 0.000;
+ tstacki_dg_ar[C][G][A][G] = -1.100;
+ tstacki_dg_ar[C][G][C][G] = 0.000;
+ tstacki_dg_ar[C][G][G][G] = 0.000;
+ tstacki_dg_ar[C][G][U][G] = 0.000;
+ tstacki_dg_ar[C][U][A][G] = 0.000;
+ tstacki_dg_ar[C][U][C][G] = 0.000;
+ tstacki_dg_ar[C][U][G][G] = 0.000;
+ tstacki_dg_ar[C][U][U][G] = -0.700;
+ tstacki_dg_ar[G][A][A][C] = 0.000;
+ tstacki_dg_ar[G][A][A][U] = 0.700;
+ tstacki_dg_ar[G][A][C][C] = 0.000;
+ tstacki_dg_ar[G][A][C][U] = 0.700;
+ tstacki_dg_ar[G][A][G][C] = -1.100;
+ tstacki_dg_ar[G][A][G][U] = -0.400;
+ tstacki_dg_ar[G][A][U][C] = 0.000;
+ tstacki_dg_ar[G][A][U][U] = 0.700;
+ tstacki_dg_ar[G][C][A][C] = 0.000;
+ tstacki_dg_ar[G][C][A][U] = 0.700;
+ tstacki_dg_ar[G][C][C][C] = 0.000;
+ tstacki_dg_ar[G][C][C][U] = 0.700;
+ tstacki_dg_ar[G][C][G][C] = 0.000;
+ tstacki_dg_ar[G][C][G][U] = 0.700;
+ tstacki_dg_ar[G][C][U][C] = 0.000;
+ tstacki_dg_ar[G][C][U][U] = 0.700;
+ tstacki_dg_ar[G][G][A][C] = -1.100;
+ tstacki_dg_ar[G][G][A][U] = -0.400;
+ tstacki_dg_ar[G][G][C][C] = 0.000;
+ tstacki_dg_ar[G][G][C][U] = 0.700;
+ tstacki_dg_ar[G][G][G][C] = 0.000;
+ tstacki_dg_ar[G][G][G][U] = 0.700;
+ tstacki_dg_ar[G][G][U][C] = 0.000;
+ tstacki_dg_ar[G][G][U][U] = 0.700;
+ tstacki_dg_ar[G][U][A][C] = 0.000;
+ tstacki_dg_ar[G][U][A][U] = 0.700;
+ tstacki_dg_ar[G][U][C][C] = 0.000;
+ tstacki_dg_ar[G][U][C][U] = 0.700;
+ tstacki_dg_ar[G][U][G][C] = 0.000;
+ tstacki_dg_ar[G][U][G][U] = 0.700;
+ tstacki_dg_ar[G][U][U][C] = -0.700;
+ tstacki_dg_ar[G][U][U][U] = 0.000;
+ tstacki_dg_ar[U][A][A][A] = 0.700;
+ tstacki_dg_ar[U][A][A][G] = 0.700;
+ tstacki_dg_ar[U][A][C][A] = 0.700;
+ tstacki_dg_ar[U][A][C][G] = 0.700;
+ tstacki_dg_ar[U][A][G][A] = -0.400;
+ tstacki_dg_ar[U][A][G][G] = -0.400;
+ tstacki_dg_ar[U][A][U][A] = 0.700;
+ tstacki_dg_ar[U][A][U][G] = 0.700;
+ tstacki_dg_ar[U][C][A][A] = 0.700;
+ tstacki_dg_ar[U][C][A][G] = 0.700;
+ tstacki_dg_ar[U][C][C][A] = 0.700;
+ tstacki_dg_ar[U][C][C][G] = 0.700;
+ tstacki_dg_ar[U][C][G][A] = 0.700;
+ tstacki_dg_ar[U][C][G][G] = 0.700;
+ tstacki_dg_ar[U][C][U][A] = 0.700;
+ tstacki_dg_ar[U][C][U][G] = 0.700;
+ tstacki_dg_ar[U][G][A][A] = -0.400;
+ tstacki_dg_ar[U][G][A][G] = -0.400;
+ tstacki_dg_ar[U][G][C][A] = 0.700;
+ tstacki_dg_ar[U][G][C][G] = 0.700;
+ tstacki_dg_ar[U][G][G][A] = 0.700;
+ tstacki_dg_ar[U][G][G][G] = 0.700;
+ tstacki_dg_ar[U][G][U][A] = 0.700;
+ tstacki_dg_ar[U][G][U][G] = 0.700;
+ tstacki_dg_ar[U][U][A][A] = 0.700;
+ tstacki_dg_ar[U][U][A][G] = 0.700;
+ tstacki_dg_ar[U][U][C][A] = 0.700;
+ tstacki_dg_ar[U][U][C][G] = 0.700;
+ tstacki_dg_ar[U][U][G][A] = 0.700;
+ tstacki_dg_ar[U][U][G][G] = 0.700;
+ tstacki_dg_ar[U][U][U][A] = 0.000;
+ tstacki_dg_ar[U][U][U][G] = 0.000;
+}
+
+void init_dr_dangle_dg_ar()
+{
+ int i,j,k;
+ for(i=0;i<ALPHASIZE;i++) for(j=0;j<ALPHASIZE;j++) for(k=0;k<=ALPHASIZE;k++) dr_dangle_dg_ar[i][j][k] = 0;
+
+ dr_dangle_dg_ar[A][U][A] = -0.700;
+ dr_dangle_dg_ar[A][U][C] = -0.100;
+ dr_dangle_dg_ar[A][U][G] = -0.700;
+ dr_dangle_dg_ar[A][U][U] = -0.100;
+ dr_dangle_dg_ar[C][G][A] = -1.100;
+ dr_dangle_dg_ar[C][G][C] = -0.400;
+ dr_dangle_dg_ar[C][G][G] = -1.300;
+ dr_dangle_dg_ar[C][G][U] = -0.600;
+ dr_dangle_dg_ar[G][C][A] = -1.700;
+ dr_dangle_dg_ar[G][C][C] = -0.800;
+ dr_dangle_dg_ar[G][C][G] = -1.700;
+ dr_dangle_dg_ar[G][C][U] = -1.200;
+ dr_dangle_dg_ar[G][U][A] = -0.700;
+ dr_dangle_dg_ar[G][U][C] = -0.100;
+ dr_dangle_dg_ar[G][U][G] = -0.700;
+ dr_dangle_dg_ar[G][U][U] = -0.100;
+ dr_dangle_dg_ar[U][A][A] = -0.800;
+ dr_dangle_dg_ar[U][A][C] = -0.500;
+ dr_dangle_dg_ar[U][A][G] = -0.800;
+ dr_dangle_dg_ar[U][A][U] = -0.600;
+ dr_dangle_dg_ar[U][G][A] = -0.800;
+ dr_dangle_dg_ar[U][G][C] = -0.500;
+ dr_dangle_dg_ar[U][G][G] = -0.800;
+ dr_dangle_dg_ar[U][G][U] = -0.600;
+
+}
+
+void init_dl_dangle_dg_ar()
+{
+ int i,j,k;
+ for(i=0;i<=ALPHASIZE;i++) for(j=0;j<ALPHASIZE;j++) for(k=0;k<ALPHASIZE;k++) dl_dangle_dg_ar[i][j][k] = 0;
+
+ dl_dangle_dg_ar[A][A][U] = -0.300;
+ dl_dangle_dg_ar[C][A][U] = -0.300;
+ dl_dangle_dg_ar[G][A][U] = -0.400;
+ dl_dangle_dg_ar[U][A][U] = -0.200;
+ dl_dangle_dg_ar[A][C][G] = -0.500;
+ dl_dangle_dg_ar[C][C][G] = -0.300;
+ dl_dangle_dg_ar[G][C][G] = -0.200;
+ dl_dangle_dg_ar[U][C][G] = -0.100;
+ dl_dangle_dg_ar[A][G][C] = -0.200;
+ dl_dangle_dg_ar[C][G][C] = -0.300;
+ dl_dangle_dg_ar[G][G][C] = 0.000;
+ dl_dangle_dg_ar[U][G][C] = 0.000;
+ dl_dangle_dg_ar[A][G][U] = -0.300;
+ dl_dangle_dg_ar[C][G][U] = -0.300;
+ dl_dangle_dg_ar[G][G][U] = -0.400;
+ dl_dangle_dg_ar[U][G][U] = -0.200;
+ dl_dangle_dg_ar[A][U][A] = -0.300;
+ dl_dangle_dg_ar[C][U][A] = -0.100;
+ dl_dangle_dg_ar[G][U][A] = -0.200;
+ dl_dangle_dg_ar[U][U][A] = -0.200;
+ dl_dangle_dg_ar[A][U][G] = -0.300;
+ dl_dangle_dg_ar[C][U][G] = -0.100;
+ dl_dangle_dg_ar[G][U][G] = -0.200;
+ dl_dangle_dg_ar[U][U][G] = -0.200;
+
+}
+
+void init_int11_ar()
+{
+ int k1,k2,k3,k4,k5,k6;
+
+ for (k1=0;k1<ALPHASIZE;k1++)
+ for (k2=0;k2<ALPHASIZE;k2++)
+ for (k3=0;k3<ALPHASIZE;k3++)
+ for (k4=0;k4<ALPHASIZE;k4++)
+ for (k5=0;k5<ALPHASIZE;k5++)
+ for (k6=0;k6<ALPHASIZE;k6++)
+ int11_ar[k1][k2][k3][k4][k5][k6]=0.0;
+
+ int11_ar[A][U][A][A][A][U] = 1.700;
+ int11_ar[A][U][A][C][A][U] = 1.700;
+ int11_ar[A][U][A][G][A][U] = 1.700;
+ int11_ar[A][U][A][U][A][U] = 1.700;
+ int11_ar[A][U][C][A][A][U] = 1.700;
+ int11_ar[A][U][C][C][A][U] = 1.700;
+ int11_ar[A][U][C][G][A][U] = 1.700;
+ int11_ar[A][U][C][U][A][U] = 1.700;
+ int11_ar[A][U][G][A][A][U] = 1.700;
+ int11_ar[A][U][G][C][A][U] = 1.700;
+ int11_ar[A][U][G][G][A][U] = -0.400;
+ int11_ar[A][U][G][U][A][U] = 1.700;
+ int11_ar[A][U][U][A][A][U] = 1.700;
+ int11_ar[A][U][U][C][A][U] = 1.700;
+ int11_ar[A][U][U][G][A][U] = 1.700;
+ int11_ar[A][U][U][U][A][U] = 1.200;
+ int11_ar[A][U][A][A][C][G] = 1.100;
+ int11_ar[A][U][A][C][C][G] = 1.100;
+ int11_ar[A][U][A][G][C][G] = 1.100;
+ int11_ar[A][U][A][U][C][G] = 1.100;
+ int11_ar[A][U][C][A][C][G] = 1.100;
+ int11_ar[A][U][C][C][C][G] = 1.100;
+ int11_ar[A][U][C][G][C][G] = 1.100;
+ int11_ar[A][U][C][U][C][G] = 1.100;
+ int11_ar[A][U][G][A][C][G] = 1.100;
+ int11_ar[A][U][G][C][C][G] = 1.100;
+ int11_ar[A][U][G][G][C][G] = -1.000;
+ int11_ar[A][U][G][U][C][G] = 1.100;
+ int11_ar[A][U][U][A][C][G] = 1.100;
+ int11_ar[A][U][U][C][C][G] = 1.100;
+ int11_ar[A][U][U][G][C][G] = 1.100;
+ int11_ar[A][U][U][U][C][G] = 1.100;
+ int11_ar[A][U][A][A][G][C] = 1.100;
+ int11_ar[A][U][A][C][G][C] = 1.100;
+ int11_ar[A][U][A][G][G][C] = 1.100;
+ int11_ar[A][U][A][U][G][C] = 1.100;
+ int11_ar[A][U][C][A][G][C] = 1.100;
+ int11_ar[A][U][C][C][G][C] = 1.100;
+ int11_ar[A][U][C][G][G][C] = 1.100;
+ int11_ar[A][U][C][U][G][C] = 1.100;
+ int11_ar[A][U][G][A][G][C] = 1.100;
+ int11_ar[A][U][G][C][G][C] = 1.100;
+ int11_ar[A][U][G][G][G][C] = -1.000;
+ int11_ar[A][U][G][U][G][C] = 1.100;
+ int11_ar[A][U][U][A][G][C] = 1.100;
+ int11_ar[A][U][U][C][G][C] = 1.100;
+ int11_ar[A][U][U][G][G][C] = 1.100;
+ int11_ar[A][U][U][U][G][C] = 1.000;
+ int11_ar[A][U][A][A][G][U] = 1.700;
+ int11_ar[A][U][A][C][G][U] = 1.700;
+ int11_ar[A][U][A][G][G][U] = 1.700;
+ int11_ar[A][U][A][U][G][U] = 1.700;
+ int11_ar[A][U][C][A][G][U] = 1.700;
+ int11_ar[A][U][C][C][G][U] = 1.700;
+ int11_ar[A][U][C][G][G][U] = 1.700;
+ int11_ar[A][U][C][U][G][U] = 1.700;
+ int11_ar[A][U][G][A][G][U] = 1.700;
+ int11_ar[A][U][G][C][G][U] = 1.700;
+ int11_ar[A][U][G][G][G][U] = -0.400;
+ int11_ar[A][U][G][U][G][U] = 1.700;
+ int11_ar[A][U][U][A][G][U] = 1.700;
+ int11_ar[A][U][U][C][G][U] = 1.700;
+ int11_ar[A][U][U][G][G][U] = 1.700;
+ int11_ar[A][U][U][U][G][U] = 1.700;
+ int11_ar[A][U][A][A][U][A] = 1.700;
+ int11_ar[A][U][A][C][U][A] = 1.700;
+ int11_ar[A][U][A][G][U][A] = 1.700;
+ int11_ar[A][U][A][U][U][A] = 1.700;
+ int11_ar[A][U][C][A][U][A] = 1.700;
+ int11_ar[A][U][C][C][U][A] = 1.700;
+ int11_ar[A][U][C][G][U][A] = 1.700;
+ int11_ar[A][U][C][U][U][A] = 1.700;
+ int11_ar[A][U][G][A][U][A] = 1.700;
+ int11_ar[A][U][G][C][U][A] = 1.700;
+ int11_ar[A][U][G][G][U][A] = -0.400;
+ int11_ar[A][U][G][U][U][A] = 1.700;
+ int11_ar[A][U][U][A][U][A] = 1.700;
+ int11_ar[A][U][U][C][U][A] = 1.700;
+ int11_ar[A][U][U][G][U][A] = 1.700;
+ int11_ar[A][U][U][U][U][A] = 1.500;
+ int11_ar[A][U][A][A][U][G] = 1.700;
+ int11_ar[A][U][A][C][U][G] = 1.700;
+ int11_ar[A][U][A][G][U][G] = 1.700;
+ int11_ar[A][U][A][U][U][G] = 1.700;
+ int11_ar[A][U][C][A][U][G] = 1.700;
+ int11_ar[A][U][C][C][U][G] = 1.700;
+ int11_ar[A][U][C][G][U][G] = 1.700;
+ int11_ar[A][U][C][U][U][G] = 1.700;
+ int11_ar[A][U][G][A][U][G] = 1.700;
+ int11_ar[A][U][G][C][U][G] = 1.700;
+ int11_ar[A][U][G][G][U][G] = -0.400;
+ int11_ar[A][U][G][U][U][G] = 1.700;
+ int11_ar[A][U][U][A][U][G] = 1.700;
+ int11_ar[A][U][U][C][U][G] = 1.700;
+ int11_ar[A][U][U][G][U][G] = 1.700;
+ int11_ar[A][U][U][U][U][G] = 1.700;
+ int11_ar[C][G][A][A][A][U] = 1.100;
+ int11_ar[C][G][A][C][A][U] = 1.100;
+ int11_ar[C][G][A][G][A][U] = 1.100;
+ int11_ar[C][G][A][U][A][U] = 1.100;
+ int11_ar[C][G][C][A][A][U] = 1.100;
+ int11_ar[C][G][C][C][A][U] = 1.100;
+ int11_ar[C][G][C][G][A][U] = 1.100;
+ int11_ar[C][G][C][U][A][U] = 1.100;
+ int11_ar[C][G][G][A][A][U] = 1.100;
+ int11_ar[C][G][G][C][A][U] = 1.100;
+ int11_ar[C][G][G][G][A][U] = -1.000;
+ int11_ar[C][G][G][U][A][U] = 1.100;
+ int11_ar[C][G][U][A][A][U] = 1.100;
+ int11_ar[C][G][U][C][A][U] = 1.100;
+ int11_ar[C][G][U][G][A][U] = 1.100;
+ int11_ar[C][G][U][U][A][U] = 1.100;
+ int11_ar[C][G][A][A][C][G] = 1.100;
+ int11_ar[C][G][A][C][C][G] = 0.400;
+ int11_ar[C][G][A][G][C][G] = 0.400;
+ int11_ar[C][G][A][U][C][G] = 0.400;
+ int11_ar[C][G][C][A][C][G] = 0.400;
+ int11_ar[C][G][C][C][C][G] = 0.400;
+ int11_ar[C][G][C][G][C][G] = 0.400;
+ int11_ar[C][G][C][U][C][G] = 0.400;
+ int11_ar[C][G][G][A][C][G] = 0.400;
+ int11_ar[C][G][G][C][C][G] = 0.400;
+ int11_ar[C][G][G][G][C][G] = -1.400;
+ int11_ar[C][G][G][U][C][G] = 0.400;
+ int11_ar[C][G][U][A][C][G] = 0.400;
+ int11_ar[C][G][U][C][C][G] = 0.400;
+ int11_ar[C][G][U][G][C][G] = 0.400;
+ int11_ar[C][G][U][U][C][G] = 0.400;
+ int11_ar[C][G][A][A][G][C] = 0.400;
+ int11_ar[C][G][A][C][G][C] = -0.400;
+ int11_ar[C][G][A][G][G][C] = 0.400;
+ int11_ar[C][G][A][U][G][C] = 0.400;
+ int11_ar[C][G][C][A][G][C] = 0.300;
+ int11_ar[C][G][C][C][G][C] = 0.500;
+ int11_ar[C][G][C][G][G][C] = 0.400;
+ int11_ar[C][G][C][U][G][C] = 0.500;
+ int11_ar[C][G][G][A][G][C] = -0.100;
+ int11_ar[C][G][G][C][G][C] = 0.400;
+ int11_ar[C][G][G][G][G][C] = -1.700;
+ int11_ar[C][G][G][U][G][C] = 0.400;
+ int11_ar[C][G][U][A][G][C] = 0.400;
+ int11_ar[C][G][U][C][G][C] = 0.000;
+ int11_ar[C][G][U][G][G][C] = 0.400;
+ int11_ar[C][G][U][U][G][C] = -0.300;
+ int11_ar[C][G][A][A][G][U] = 1.100;
+ int11_ar[C][G][A][C][G][U] = 1.100;
+ int11_ar[C][G][A][G][G][U] = 1.100;
+ int11_ar[C][G][A][U][G][U] = 1.100;
+ int11_ar[C][G][C][A][G][U] = 1.100;
+ int11_ar[C][G][C][C][G][U] = 1.100;
+ int11_ar[C][G][C][G][G][U] = 1.100;
+ int11_ar[C][G][C][U][G][U] = 1.100;
+ int11_ar[C][G][G][A][G][U] = 1.100;
+ int11_ar[C][G][G][C][G][U] = 1.100;
+ int11_ar[C][G][G][G][G][U] = -1.000;
+ int11_ar[C][G][G][U][G][U] = 1.100;
+ int11_ar[C][G][U][A][G][U] = 1.100;
+ int11_ar[C][G][U][C][G][U] = 1.100;
+ int11_ar[C][G][U][G][G][U] = 1.100;
+ int11_ar[C][G][U][U][G][U] = 1.100;
+ int11_ar[C][G][A][A][U][A] = 1.100;
+ int11_ar[C][G][A][C][U][A] = 1.100;
+ int11_ar[C][G][A][G][U][A] = 1.100;
+ int11_ar[C][G][A][U][U][A] = 1.100;
+ int11_ar[C][G][C][A][U][A] = 1.100;
+ int11_ar[C][G][C][C][U][A] = 1.100;
+ int11_ar[C][G][C][G][U][A] = 1.100;
+ int11_ar[C][G][C][U][U][A] = 1.100;
+ int11_ar[C][G][G][A][U][A] = 1.100;
+ int11_ar[C][G][G][C][U][A] = 1.100;
+ int11_ar[C][G][G][G][U][A] = -1.000;
+ int11_ar[C][G][G][U][U][A] = 1.100;
+ int11_ar[C][G][U][A][U][A] = 1.100;
+ int11_ar[C][G][U][C][U][A] = 1.100;
+ int11_ar[C][G][U][G][U][A] = 1.100;
+ int11_ar[C][G][U][U][U][A] = 1.100;
+ int11_ar[C][G][A][A][U][G] = 1.100;
+ int11_ar[C][G][A][C][U][G] = 1.100;
+ int11_ar[C][G][A][G][U][G] = 1.100;
+ int11_ar[C][G][A][U][U][G] = 1.100;
+ int11_ar[C][G][C][A][U][G] = 1.100;
+ int11_ar[C][G][C][C][U][G] = 1.100;
+ int11_ar[C][G][C][G][U][G] = 1.100;
+ int11_ar[C][G][C][U][U][G] = 1.100;
+ int11_ar[C][G][G][A][U][G] = 1.100;
+ int11_ar[C][G][G][C][U][G] = 1.100;
+ int11_ar[C][G][G][G][U][G] = -1.000;
+ int11_ar[C][G][G][U][U][G] = 1.100;
+ int11_ar[C][G][U][A][U][G] = 1.100;
+ int11_ar[C][G][U][C][U][G] = 1.100;
+ int11_ar[C][G][U][G][U][G] = 1.100;
+ int11_ar[C][G][U][U][U][G] = 1.100;
+ int11_ar[G][C][A][A][A][U] = 1.100;
+ int11_ar[G][C][A][C][A][U] = 1.100;
+ int11_ar[G][C][A][G][A][U] = 1.100;
+ int11_ar[G][C][A][U][A][U] = 1.100;
+ int11_ar[G][C][C][A][A][U] = 1.100;
+ int11_ar[G][C][C][C][A][U] = 1.100;
+ int11_ar[G][C][C][G][A][U] = 1.100;
+ int11_ar[G][C][C][U][A][U] = 1.100;
+ int11_ar[G][C][G][A][A][U] = 1.100;
+ int11_ar[G][C][G][C][A][U] = 1.100;
+ int11_ar[G][C][G][G][A][U] = -1.000;
+ int11_ar[G][C][G][U][A][U] = 1.100;
+ int11_ar[G][C][U][A][A][U] = 1.100;
+ int11_ar[G][C][U][C][A][U] = 1.100;
+ int11_ar[G][C][U][G][A][U] = 1.100;
+ int11_ar[G][C][U][U][A][U] = 1.000;
+ int11_ar[G][C][A][A][C][G] = 0.400;
+ int11_ar[G][C][A][C][C][G] = 0.300;
+ int11_ar[G][C][A][G][C][G] = -0.100;
+ int11_ar[G][C][A][U][C][G] = 0.400;
+ int11_ar[G][C][C][A][C][G] = -0.400;
+ int11_ar[G][C][C][C][C][G] = 0.500;
+ int11_ar[G][C][C][G][C][G] = 0.400;
+ int11_ar[G][C][C][U][C][G] = 0.000;
+ int11_ar[G][C][G][A][C][G] = 0.400;
+ int11_ar[G][C][G][C][C][G] = 0.400;
+ int11_ar[G][C][G][G][C][G] = -1.700;
+ int11_ar[G][C][G][U][C][G] = 0.400;
+ int11_ar[G][C][U][A][C][G] = 0.400;
+ int11_ar[G][C][U][C][C][G] = 0.500;
+ int11_ar[G][C][U][G][C][G] = 0.400;
+ int11_ar[G][C][U][U][C][G] = -0.300;
+ int11_ar[G][C][A][A][G][C] = 0.800;
+ int11_ar[G][C][A][C][G][C] = 0.400;
+ int11_ar[G][C][A][G][G][C] = 0.400;
+ int11_ar[G][C][A][U][G][C] = 0.400;
+ int11_ar[G][C][C][A][G][C] = 0.400;
+ int11_ar[G][C][C][C][G][C] = 0.400;
+ int11_ar[G][C][C][G][G][C] = 0.400;
+ int11_ar[G][C][C][U][G][C] = 0.400;
+ int11_ar[G][C][G][A][G][C] = 0.400;
+ int11_ar[G][C][G][C][G][C] = 0.400;
+ int11_ar[G][C][G][G][G][C] = -2.100;
+ int11_ar[G][C][G][U][G][C] = 0.400;
+ int11_ar[G][C][U][A][G][C] = 0.400;
+ int11_ar[G][C][U][C][G][C] = 0.400;
+ int11_ar[G][C][U][G][G][C] = 0.400;
+ int11_ar[G][C][U][U][G][C] = -0.700;
+ int11_ar[G][C][A][A][G][U] = 1.100;
+ int11_ar[G][C][A][C][G][U] = 1.100;
+ int11_ar[G][C][A][G][G][U] = 1.100;
+ int11_ar[G][C][A][U][G][U] = 1.100;
+ int11_ar[G][C][C][A][G][U] = 1.100;
+ int11_ar[G][C][C][C][G][U] = 1.100;
+ int11_ar[G][C][C][G][G][U] = 1.100;
+ int11_ar[G][C][C][U][G][U] = 1.100;
+ int11_ar[G][C][G][A][G][U] = 1.100;
+ int11_ar[G][C][G][C][G][U] = 1.100;
+ int11_ar[G][C][G][G][G][U] = -1.000;
+ int11_ar[G][C][G][U][G][U] = 1.100;
+ int11_ar[G][C][U][A][G][U] = 1.100;
+ int11_ar[G][C][U][C][G][U] = 1.100;
+ int11_ar[G][C][U][G][G][U] = 1.100;
+ int11_ar[G][C][U][U][G][U] = 1.100;
+ int11_ar[G][C][A][A][U][A] = 1.100;
+ int11_ar[G][C][A][C][U][A] = 1.100;
+ int11_ar[G][C][A][G][U][A] = 1.100;
+ int11_ar[G][C][A][U][U][A] = 1.100;
+ int11_ar[G][C][C][A][U][A] = 1.100;
+ int11_ar[G][C][C][C][U][A] = 1.100;
+ int11_ar[G][C][C][G][U][A] = 1.100;
+ int11_ar[G][C][C][U][U][A] = 1.100;
+ int11_ar[G][C][G][A][U][A] = 1.100;
+ int11_ar[G][C][G][C][U][A] = 1.100;
+ int11_ar[G][C][G][G][U][A] = -1.000;
+ int11_ar[G][C][G][U][U][A] = 1.100;
+ int11_ar[G][C][U][A][U][A] = 1.100;
+ int11_ar[G][C][U][C][U][A] = 1.100;
+ int11_ar[G][C][U][G][U][A] = 1.100;
+ int11_ar[G][C][U][U][U][A] = 1.100;
+ int11_ar[G][C][A][A][U][G] = 1.100;
+ int11_ar[G][C][A][C][U][G] = 1.100;
+ int11_ar[G][C][A][G][U][G] = 1.100;
+ int11_ar[G][C][A][U][U][G] = 1.100;
+ int11_ar[G][C][C][A][U][G] = 1.100;
+ int11_ar[G][C][C][C][U][G] = 1.100;
+ int11_ar[G][C][C][G][U][G] = 1.100;
+ int11_ar[G][C][C][U][U][G] = 1.100;
+ int11_ar[G][C][G][A][U][G] = 1.100;
+ int11_ar[G][C][G][C][U][G] = 1.100;
+ int11_ar[G][C][G][G][U][G] = -1.000;
+ int11_ar[G][C][G][U][U][G] = 1.100;
+ int11_ar[G][C][U][A][U][G] = 1.100;
+ int11_ar[G][C][U][C][U][G] = 1.100;
+ int11_ar[G][C][U][G][U][G] = 1.100;
+ int11_ar[G][C][U][U][U][G] = 1.100;
+ int11_ar[G][U][A][A][A][U] = 1.700;
+ int11_ar[G][U][A][C][A][U] = 1.700;
+ int11_ar[G][U][A][G][A][U] = 1.700;
+ int11_ar[G][U][A][U][A][U] = 1.700;
+ int11_ar[G][U][C][A][A][U] = 1.700;
+ int11_ar[G][U][C][C][A][U] = 1.700;
+ int11_ar[G][U][C][G][A][U] = 1.700;
+ int11_ar[G][U][C][U][A][U] = 1.700;
+ int11_ar[G][U][G][A][A][U] = 1.700;
+ int11_ar[G][U][G][C][A][U] = 1.700;
+ int11_ar[G][U][G][G][A][U] = -0.400;
+ int11_ar[G][U][G][U][A][U] = 1.700;
+ int11_ar[G][U][U][A][A][U] = 1.700;
+ int11_ar[G][U][U][C][A][U] = 1.700;
+ int11_ar[G][U][U][G][A][U] = 1.700;
+ int11_ar[G][U][U][U][A][U] = 1.700;
+ int11_ar[G][U][A][A][C][G] = 1.100;
+ int11_ar[G][U][A][C][C][G] = 1.100;
+ int11_ar[G][U][A][G][C][G] = 1.100;
+ int11_ar[G][U][A][U][C][G] = 1.100;
+ int11_ar[G][U][C][A][C][G] = 1.100;
+ int11_ar[G][U][C][C][C][G] = 1.100;
+ int11_ar[G][U][C][G][C][G] = 1.100;
+ int11_ar[G][U][C][U][C][G] = 1.100;
+ int11_ar[G][U][G][A][C][G] = 1.100;
+ int11_ar[G][U][G][C][C][G] = 1.100;
+ int11_ar[G][U][G][G][C][G] = -1.000;
+ int11_ar[G][U][G][U][C][G] = 1.100;
+ int11_ar[G][U][U][A][C][G] = 1.100;
+ int11_ar[G][U][U][C][C][G] = 1.100;
+ int11_ar[G][U][U][G][C][G] = 1.100;
+ int11_ar[G][U][U][U][C][G] = 1.100;
+ int11_ar[G][U][A][A][G][C] = 1.100;
+ int11_ar[G][U][A][C][G][C] = 1.100;
+ int11_ar[G][U][A][G][G][C] = 1.100;
+ int11_ar[G][U][A][U][G][C] = 1.100;
+ int11_ar[G][U][C][A][G][C] = 1.100;
+ int11_ar[G][U][C][C][G][C] = 1.100;
+ int11_ar[G][U][C][G][G][C] = 1.100;
+ int11_ar[G][U][C][U][G][C] = 1.100;
+ int11_ar[G][U][G][A][G][C] = 1.100;
+ int11_ar[G][U][G][C][G][C] = 1.100;
+ int11_ar[G][U][G][G][G][C] = -1.000;
+ int11_ar[G][U][G][U][G][C] = 1.100;
+ int11_ar[G][U][U][A][G][C] = 1.100;
+ int11_ar[G][U][U][C][G][C] = 1.100;
+ int11_ar[G][U][U][G][G][C] = 1.100;
+ int11_ar[G][U][U][U][G][C] = 1.100;
+ int11_ar[G][U][A][A][G][U] = 1.700;
+ int11_ar[G][U][A][C][G][U] = 1.700;
+ int11_ar[G][U][A][G][G][U] = 1.700;
+ int11_ar[G][U][A][U][G][U] = 1.700;
+ int11_ar[G][U][C][A][G][U] = 1.700;
+ int11_ar[G][U][C][C][G][U] = 1.700;
+ int11_ar[G][U][C][G][G][U] = 1.700;
+ int11_ar[G][U][C][U][G][U] = 1.700;
+ int11_ar[G][U][G][A][G][U] = 1.700;
+ int11_ar[G][U][G][C][G][U] = 1.700;
+ int11_ar[G][U][G][G][G][U] = -0.400;
+ int11_ar[G][U][G][U][G][U] = 1.700;
+ int11_ar[G][U][U][A][G][U] = 1.700;
+ int11_ar[G][U][U][C][G][U] = 1.700;
+ int11_ar[G][U][U][G][G][U] = 1.700;
+ int11_ar[G][U][U][U][G][U] = 1.700;
+ int11_ar[G][U][A][A][U][A] = 1.700;
+ int11_ar[G][U][A][C][U][A] = 1.700;
+ int11_ar[G][U][A][G][U][A] = 1.700;
+ int11_ar[G][U][A][U][U][A] = 1.700;
+ int11_ar[G][U][C][A][U][A] = 1.700;
+ int11_ar[G][U][C][C][U][A] = 1.700;
+ int11_ar[G][U][C][G][U][A] = 1.700;
+ int11_ar[G][U][C][U][U][A] = 1.700;
+ int11_ar[G][U][G][A][U][A] = 1.700;
+ int11_ar[G][U][G][C][U][A] = 1.700;
+ int11_ar[G][U][G][G][U][A] = -0.400;
+ int11_ar[G][U][G][U][U][A] = 1.700;
+ int11_ar[G][U][U][A][U][A] = 1.700;
+ int11_ar[G][U][U][C][U][A] = 1.700;
+ int11_ar[G][U][U][G][U][A] = 1.700;
+ int11_ar[G][U][U][U][U][A] = 1.700;
+ int11_ar[G][U][A][A][U][G] = 1.700;
+ int11_ar[G][U][A][C][U][G] = 1.700;
+ int11_ar[G][U][A][G][U][G] = 1.700;
+ int11_ar[G][U][A][U][U][G] = 1.700;
+ int11_ar[G][U][C][A][U][G] = 1.700;
+ int11_ar[G][U][C][C][U][G] = 1.700;
+ int11_ar[G][U][C][G][U][G] = 1.700;
+ int11_ar[G][U][C][U][U][G] = 1.700;
+ int11_ar[G][U][G][A][U][G] = 1.700;
+ int11_ar[G][U][G][C][U][G] = 1.700;
+ int11_ar[G][U][G][G][U][G] = -0.400;
+ int11_ar[G][U][G][U][U][G] = 1.700;
+ int11_ar[G][U][U][A][U][G] = 1.700;
+ int11_ar[G][U][U][C][U][G] = 1.700;
+ int11_ar[G][U][U][G][U][G] = 1.700;
+ int11_ar[G][U][U][U][U][G] = 1.700;
+ int11_ar[U][A][A][A][A][U] = 1.700;
+ int11_ar[U][A][A][C][A][U] = 1.700;
+ int11_ar[U][A][A][G][A][U] = 1.700;
+ int11_ar[U][A][A][U][A][U] = 1.700;
+ int11_ar[U][A][C][A][A][U] = 1.700;
+ int11_ar[U][A][C][C][A][U] = 1.700;
+ int11_ar[U][A][C][G][A][U] = 1.700;
+ int11_ar[U][A][C][U][A][U] = 1.700;
+ int11_ar[U][A][G][A][A][U] = 1.700;
+ int11_ar[U][A][G][C][A][U] = 1.700;
+ int11_ar[U][A][G][G][A][U] = -0.400;
+ int11_ar[U][A][G][U][A][U] = 1.700;
+ int11_ar[U][A][U][A][A][U] = 1.700;
+ int11_ar[U][A][U][C][A][U] = 1.700;
+ int11_ar[U][A][U][G][A][U] = 1.700;
+ int11_ar[U][A][U][U][A][U] = 1.500;
+ int11_ar[U][A][A][A][C][G] = 1.100;
+ int11_ar[U][A][A][C][C][G] = 1.100;
+ int11_ar[U][A][A][G][C][G] = 1.100;
+ int11_ar[U][A][A][U][C][G] = 1.100;
+ int11_ar[U][A][C][A][C][G] = 1.100;
+ int11_ar[U][A][C][C][C][G] = 1.100;
+ int11_ar[U][A][C][G][C][G] = 1.100;
+ int11_ar[U][A][C][U][C][G] = 1.100;
+ int11_ar[U][A][G][A][C][G] = 1.100;
+ int11_ar[U][A][G][C][C][G] = 1.100;
+ int11_ar[U][A][G][G][C][G] = -1.000;
+ int11_ar[U][A][G][U][C][G] = 1.100;
+ int11_ar[U][A][U][A][C][G] = 1.100;
+ int11_ar[U][A][U][C][C][G] = 1.100;
+ int11_ar[U][A][U][G][C][G] = 1.100;
+ int11_ar[U][A][U][U][C][G] = 1.100;
+ int11_ar[U][A][A][A][G][C] = 1.100;
+ int11_ar[U][A][A][C][G][C] = 1.100;
+ int11_ar[U][A][A][G][G][C] = 1.100;
+ int11_ar[U][A][A][U][G][C] = 1.100;
+ int11_ar[U][A][C][A][G][C] = 1.100;
+ int11_ar[U][A][C][C][G][C] = 1.100;
+ int11_ar[U][A][C][G][G][C] = 1.100;
+ int11_ar[U][A][C][U][G][C] = 1.100;
+ int11_ar[U][A][G][A][G][C] = 1.100;
+ int11_ar[U][A][G][C][G][C] = 1.100;
+ int11_ar[U][A][G][G][G][C] = -1.000;
+ int11_ar[U][A][G][U][G][C] = 1.100;
+ int11_ar[U][A][U][A][G][C] = 1.100;
+ int11_ar[U][A][U][C][G][C] = 1.100;
+ int11_ar[U][A][U][G][G][C] = 1.100;
+ int11_ar[U][A][U][U][G][C] = 1.100;
+ int11_ar[U][A][A][A][G][U] = 1.700;
+ int11_ar[U][A][A][C][G][U] = 1.700;
+ int11_ar[U][A][A][G][G][U] = 1.700;
+ int11_ar[U][A][A][U][G][U] = 1.700;
+ int11_ar[U][A][C][A][G][U] = 1.700;
+ int11_ar[U][A][C][C][G][U] = 1.700;
+ int11_ar[U][A][C][G][G][U] = 1.700;
+ int11_ar[U][A][C][U][G][U] = 1.700;
+ int11_ar[U][A][G][A][G][U] = 1.700;
+ int11_ar[U][A][G][C][G][U] = 1.700;
+ int11_ar[U][A][G][G][G][U] = -0.400;
+ int11_ar[U][A][G][U][G][U] = 1.700;
+ int11_ar[U][A][U][A][G][U] = 1.700;
+ int11_ar[U][A][U][C][G][U] = 1.700;
+ int11_ar[U][A][U][G][G][U] = 1.700;
+ int11_ar[U][A][U][U][G][U] = 1.700;
+ int11_ar[U][A][A][A][U][A] = 1.700;
+ int11_ar[U][A][A][C][U][A] = 1.700;
+ int11_ar[U][A][A][G][U][A] = 1.700;
+ int11_ar[U][A][A][U][U][A] = 1.700;
+ int11_ar[U][A][C][A][U][A] = 1.700;
+ int11_ar[U][A][C][C][U][A] = 1.700;
+ int11_ar[U][A][C][G][U][A] = 1.700;
+ int11_ar[U][A][C][U][U][A] = 1.700;
+ int11_ar[U][A][G][A][U][A] = 1.700;
+ int11_ar[U][A][G][C][U][A] = 1.700;
+ int11_ar[U][A][G][G][U][A] = -0.400;
+ int11_ar[U][A][G][U][U][A] = 1.700;
+ int11_ar[U][A][U][A][U][A] = 1.700;
+ int11_ar[U][A][U][C][U][A] = 1.700;
+ int11_ar[U][A][U][G][U][A] = 1.700;
+ int11_ar[U][A][U][U][U][A] = 1.800;
+ int11_ar[U][A][A][A][U][G] = 1.700;
+ int11_ar[U][A][A][C][U][G] = 1.700;
+ int11_ar[U][A][A][G][U][G] = 1.700;
+ int11_ar[U][A][A][U][U][G] = 1.700;
+ int11_ar[U][A][C][A][U][G] = 1.700;
+ int11_ar[U][A][C][C][U][G] = 1.700;
+ int11_ar[U][A][C][G][U][G] = 1.700;
+ int11_ar[U][A][C][U][U][G] = 1.700;
+ int11_ar[U][A][G][A][U][G] = 1.700;
+ int11_ar[U][A][G][C][U][G] = 1.700;
+ int11_ar[U][A][G][G][U][G] = -0.400;
+ int11_ar[U][A][G][U][U][G] = 1.700;
+ int11_ar[U][A][U][A][U][G] = 1.700;
+ int11_ar[U][A][U][C][U][G] = 1.700;
+ int11_ar[U][A][U][G][U][G] = 1.700;
+ int11_ar[U][A][U][U][U][G] = 1.700;
+ int11_ar[U][G][A][A][A][U] = 1.700;
+ int11_ar[U][G][A][C][A][U] = 1.700;
+ int11_ar[U][G][A][G][A][U] = 1.700;
+ int11_ar[U][G][A][U][A][U] = 1.700;
+ int11_ar[U][G][C][A][A][U] = 1.700;
+ int11_ar[U][G][C][C][A][U] = 1.700;
+ int11_ar[U][G][C][G][A][U] = 1.700;
+ int11_ar[U][G][C][U][A][U] = 1.700;
+ int11_ar[U][G][G][A][A][U] = 1.700;
+ int11_ar[U][G][G][C][A][U] = 1.700;
+ int11_ar[U][G][G][G][A][U] = -0.400;
+ int11_ar[U][G][G][U][A][U] = 1.700;
+ int11_ar[U][G][U][A][A][U] = 1.700;
+ int11_ar[U][G][U][C][A][U] = 1.700;
+ int11_ar[U][G][U][G][A][U] = 1.700;
+ int11_ar[U][G][U][U][A][U] = 1.700;
+ int11_ar[U][G][A][A][C][G] = 1.100;
+ int11_ar[U][G][A][C][C][G] = 1.100;
+ int11_ar[U][G][A][G][C][G] = 1.100;
+ int11_ar[U][G][A][U][C][G] = 1.100;
+ int11_ar[U][G][C][A][C][G] = 1.100;
+ int11_ar[U][G][C][C][C][G] = 1.100;
+ int11_ar[U][G][C][G][C][G] = 1.100;
+ int11_ar[U][G][C][U][C][G] = 1.100;
+ int11_ar[U][G][G][A][C][G] = 1.100;
+ int11_ar[U][G][G][C][C][G] = 1.100;
+ int11_ar[U][G][G][G][C][G] = -1.000;
+ int11_ar[U][G][G][U][C][G] = 1.100;
+ int11_ar[U][G][U][A][C][G] = 1.100;
+ int11_ar[U][G][U][C][C][G] = 1.100;
+ int11_ar[U][G][U][G][C][G] = 1.100;
+ int11_ar[U][G][U][U][C][G] = 1.100;
+ int11_ar[U][G][A][A][G][C] = 1.100;
+ int11_ar[U][G][A][C][G][C] = 1.100;
+ int11_ar[U][G][A][G][G][C] = 1.100;
+ int11_ar[U][G][A][U][G][C] = 1.100;
+ int11_ar[U][G][C][A][G][C] = 1.100;
+ int11_ar[U][G][C][C][G][C] = 1.100;
+ int11_ar[U][G][C][G][G][C] = 1.100;
+ int11_ar[U][G][C][U][G][C] = 1.100;
+ int11_ar[U][G][G][A][G][C] = 1.100;
+ int11_ar[U][G][G][C][G][C] = 1.100;
+ int11_ar[U][G][G][G][G][C] = -1.000;
+ int11_ar[U][G][G][U][G][C] = 1.100;
+ int11_ar[U][G][U][A][G][C] = 1.100;
+ int11_ar[U][G][U][C][G][C] = 1.100;
+ int11_ar[U][G][U][G][G][C] = 1.100;
+ int11_ar[U][G][U][U][G][C] = 1.100;
+ int11_ar[U][G][A][A][G][U] = 1.700;
+ int11_ar[U][G][A][C][G][U] = 1.700;
+ int11_ar[U][G][A][G][G][U] = 1.700;
+ int11_ar[U][G][A][U][G][U] = 1.700;
+ int11_ar[U][G][C][A][G][U] = 1.700;
+ int11_ar[U][G][C][C][G][U] = 1.700;
+ int11_ar[U][G][C][G][G][U] = 1.700;
+ int11_ar[U][G][C][U][G][U] = 1.700;
+ int11_ar[U][G][G][A][G][U] = 1.700;
+ int11_ar[U][G][G][C][G][U] = 1.700;
+ int11_ar[U][G][G][G][G][U] = -0.400;
+ int11_ar[U][G][G][U][G][U] = 1.700;
+ int11_ar[U][G][U][A][G][U] = 1.700;
+ int11_ar[U][G][U][C][G][U] = 1.700;
+ int11_ar[U][G][U][G][G][U] = 1.700;
+ int11_ar[U][G][U][U][G][U] = 1.700;
+ int11_ar[U][G][A][A][U][A] = 1.700;
+ int11_ar[U][G][A][C][U][A] = 1.700;
+ int11_ar[U][G][A][G][U][A] = 1.700;
+ int11_ar[U][G][A][U][U][A] = 1.700;
+ int11_ar[U][G][C][A][U][A] = 1.700;
+ int11_ar[U][G][C][C][U][A] = 1.700;
+ int11_ar[U][G][C][G][U][A] = 1.700;
+ int11_ar[U][G][C][U][U][A] = 1.700;
+ int11_ar[U][G][G][A][U][A] = 1.700;
+ int11_ar[U][G][G][C][U][A] = 1.700;
+ int11_ar[U][G][G][G][U][A] = -0.400;
+ int11_ar[U][G][G][U][U][A] = 1.700;
+ int11_ar[U][G][U][A][U][A] = 1.700;
+ int11_ar[U][G][U][C][U][A] = 1.700;
+ int11_ar[U][G][U][G][U][A] = 1.700;
+ int11_ar[U][G][U][U][U][A] = 1.700;
+ int11_ar[U][G][A][A][U][G] = 1.700;
+ int11_ar[U][G][A][C][U][G] = 1.700;
+ int11_ar[U][G][A][G][U][G] = 1.700;
+ int11_ar[U][G][A][U][U][G] = 1.700;
+ int11_ar[U][G][C][A][U][G] = 1.700;
+ int11_ar[U][G][C][C][U][G] = 1.700;
+ int11_ar[U][G][C][G][U][G] = 1.700;
+ int11_ar[U][G][C][U][U][G] = 1.700;
+ int11_ar[U][G][G][A][U][G] = 1.700;
+ int11_ar[U][G][G][C][U][G] = 1.700;
+ int11_ar[U][G][G][G][U][G] = -0.400;
+ int11_ar[U][G][G][U][U][G] = 1.700;
+ int11_ar[U][G][U][A][U][G] = 1.700;
+ int11_ar[U][G][U][C][U][G] = 1.700;
+ int11_ar[U][G][U][G][U][G] = 1.700;
+ int11_ar[U][G][U][U][U][G] = 1.700;
+}
+
+void init_int21_ar()
+{
+ int k1,k2,k3,k4,k5,k6,k7;
+
+ for (k1=0;k1<ALPHASIZE;k1++)
+ for (k2=0;k2<ALPHASIZE;k2++)
+ for (k3=0;k3<ALPHASIZE;k3++)
+ for (k4=0;k4<ALPHASIZE;k4++)
+ for (k5=0;k5<ALPHASIZE;k5++)
+ for (k6=0;k6<ALPHASIZE;k6++)
+ for (k7=0;k7<ALPHASIZE;k7++)
+ int21_ar[k1][k2][k3][k4][k5][k6][k7]=0.0;
+
+ int21_ar[A][U][A][A][A][A][U] = 3.900;
+ int21_ar[A][U][A][A][C][A][U] = 3.700;
+ int21_ar[A][U][A][A][G][A][U] = 3.100;
+ int21_ar[A][U][A][A][U][A][U] = 5.500;
+ int21_ar[A][U][A][C][A][A][U] = 3.600;
+ int21_ar[A][U][A][C][C][A][U] = 3.200;
+ int21_ar[A][U][A][C][G][A][U] = 3.100;
+ int21_ar[A][U][A][C][U][A][U] = 5.500;
+ int21_ar[A][U][A][G][A][A][U] = 2.500;
+ int21_ar[A][U][A][G][C][A][U] = 2.100;
+ int21_ar[A][U][A][G][G][A][U] = 1.900;
+ int21_ar[A][U][A][G][U][A][U] = 5.500;
+ int21_ar[A][U][A][U][A][A][U] = 5.500;
+ int21_ar[A][U][A][U][C][A][U] = 5.500;
+ int21_ar[A][U][A][U][G][A][U] = 5.500;
+ int21_ar[A][U][A][U][U][A][U] = 5.500;
+ int21_ar[A][U][C][A][A][A][U] = 3.800;
+ int21_ar[A][U][C][A][C][A][U] = 3.700;
+ int21_ar[A][U][C][A][G][A][U] = 5.500;
+ int21_ar[A][U][C][A][U][A][U] = 3.700;
+ int21_ar[A][U][C][C][A][A][U] = 3.700;
+ int21_ar[A][U][C][C][C][A][U] = 4.000;
+ int21_ar[A][U][C][C][G][A][U] = 5.500;
+ int21_ar[A][U][C][C][U][A][U] = 3.700;
+ int21_ar[A][U][C][G][A][A][U] = 5.500;
+ int21_ar[A][U][C][G][C][A][U] = 5.500;
+ int21_ar[A][U][C][G][G][A][U] = 5.500;
+ int21_ar[A][U][C][G][U][A][U] = 5.500;
+ int21_ar[A][U][C][U][A][A][U] = 4.000;
+ int21_ar[A][U][C][U][C][A][U] = 3.400;
+ int21_ar[A][U][C][U][G][A][U] = 5.500;
+ int21_ar[A][U][C][U][U][A][U] = 3.700;
+ int21_ar[A][U][G][A][A][A][U] = 3.200;
+ int21_ar[A][U][G][A][C][A][U] = 5.500;
+ int21_ar[A][U][G][A][G][A][U] = 2.300;
+ int21_ar[A][U][G][A][U][A][U] = 5.500;
+ int21_ar[A][U][G][C][A][A][U] = 5.500;
+ int21_ar[A][U][G][C][C][A][U] = 5.500;
+ int21_ar[A][U][G][C][G][A][U] = 5.500;
+ int21_ar[A][U][G][C][U][A][U] = 5.500;
+ int21_ar[A][U][G][G][A][A][U] = 2.300;
+ int21_ar[A][U][G][G][C][A][U] = 5.500;
+ int21_ar[A][U][G][G][G][A][U] = 3.700;
+ int21_ar[A][U][G][G][U][A][U] = 5.500;
+ int21_ar[A][U][G][U][A][A][U] = 5.500;
+ int21_ar[A][U][G][U][C][A][U] = 5.500;
+ int21_ar[A][U][G][U][G][A][U] = 5.500;
+ int21_ar[A][U][G][U][U][A][U] = 5.500;
+ int21_ar[A][U][U][A][A][A][U] = 5.500;
+ int21_ar[A][U][U][A][C][A][U] = 5.500;
+ int21_ar[A][U][U][A][G][A][U] = 5.500;
+ int21_ar[A][U][U][A][U][A][U] = 5.500;
+ int21_ar[A][U][U][C][A][A][U] = 5.500;
+ int21_ar[A][U][U][C][C][A][U] = 3.700;
+ int21_ar[A][U][U][C][G][A][U] = 5.500;
+ int21_ar[A][U][U][C][U][A][U] = 2.800;
+ int21_ar[A][U][U][G][A][A][U] = 5.500;
+ int21_ar[A][U][U][G][C][A][U] = 5.500;
+ int21_ar[A][U][U][G][G][A][U] = 5.500;
+ int21_ar[A][U][U][G][U][A][U] = 5.500;
+ int21_ar[A][U][U][U][A][A][U] = 5.500;
+ int21_ar[A][U][U][U][C][A][U] = 3.200;
+ int21_ar[A][U][U][U][G][A][U] = 5.500;
+ int21_ar[A][U][U][U][U][A][U] = 2.700;
+ int21_ar[A][U][A][A][A][C][G] = 3.200;
+ int21_ar[A][U][A][A][C][C][G] = 3.000;
+ int21_ar[A][U][A][A][G][C][G] = 2.400;
+ int21_ar[A][U][A][A][U][C][G] = 4.800;
+ int21_ar[A][U][A][C][A][C][G] = 2.900;
+ int21_ar[A][U][A][C][C][C][G] = 2.500;
+ int21_ar[A][U][A][C][G][C][G] = 2.400;
+ int21_ar[A][U][A][C][U][C][G] = 4.800;
+ int21_ar[A][U][A][G][A][C][G] = 1.800;
+ int21_ar[A][U][A][G][C][C][G] = 1.400;
+ int21_ar[A][U][A][G][G][C][G] = 1.200;
+ int21_ar[A][U][A][G][U][C][G] = 4.800;
+ int21_ar[A][U][A][U][A][C][G] = 4.800;
+ int21_ar[A][U][A][U][C][C][G] = 4.800;
+ int21_ar[A][U][A][U][G][C][G] = 4.800;
+ int21_ar[A][U][A][U][U][C][G] = 4.800;
+ int21_ar[A][U][C][A][A][C][G] = 3.100;
+ int21_ar[A][U][C][A][C][C][G] = 3.000;
+ int21_ar[A][U][C][A][G][C][G] = 4.800;
+ int21_ar[A][U][C][A][U][C][G] = 3.000;
+ int21_ar[A][U][C][C][A][C][G] = 3.000;
+ int21_ar[A][U][C][C][C][C][G] = 3.300;
+ int21_ar[A][U][C][C][G][C][G] = 4.800;
+ int21_ar[A][U][C][C][U][C][G] = 3.000;
+ int21_ar[A][U][C][G][A][C][G] = 4.800;
+ int21_ar[A][U][C][G][C][C][G] = 4.800;
+ int21_ar[A][U][C][G][G][C][G] = 4.800;
+ int21_ar[A][U][C][G][U][C][G] = 4.800;
+ int21_ar[A][U][C][U][A][C][G] = 3.300;
+ int21_ar[A][U][C][U][C][C][G] = 2.700;
+ int21_ar[A][U][C][U][G][C][G] = 4.800;
+ int21_ar[A][U][C][U][U][C][G] = 3.000;
+ int21_ar[A][U][G][A][A][C][G] = 2.500;
+ int21_ar[A][U][G][A][C][C][G] = 4.800;
+ int21_ar[A][U][G][A][G][C][G] = 1.600;
+ int21_ar[A][U][G][A][U][C][G] = 4.800;
+ int21_ar[A][U][G][C][A][C][G] = 4.800;
+ int21_ar[A][U][G][C][C][C][G] = 4.800;
+ int21_ar[A][U][G][C][G][C][G] = 4.800;
+ int21_ar[A][U][G][C][U][C][G] = 4.800;
+ int21_ar[A][U][G][G][A][C][G] = 1.600;
+ int21_ar[A][U][G][G][C][C][G] = 4.800;
+ int21_ar[A][U][G][G][G][C][G] = 3.000;
+ int21_ar[A][U][G][G][U][C][G] = 4.800;
+ int21_ar[A][U][G][U][A][C][G] = 4.800;
+ int21_ar[A][U][G][U][C][C][G] = 4.800;
+ int21_ar[A][U][G][U][G][C][G] = 4.800;
+ int21_ar[A][U][G][U][U][C][G] = 4.800;
+ int21_ar[A][U][U][A][A][C][G] = 4.800;
+ int21_ar[A][U][U][A][C][C][G] = 4.800;
+ int21_ar[A][U][U][A][G][C][G] = 4.800;
+ int21_ar[A][U][U][A][U][C][G] = 4.800;
+ int21_ar[A][U][U][C][A][C][G] = 4.800;
+ int21_ar[A][U][U][C][C][C][G] = 3.000;
+ int21_ar[A][U][U][C][G][C][G] = 4.800;
+ int21_ar[A][U][U][C][U][C][G] = 2.100;
+ int21_ar[A][U][U][G][A][C][G] = 4.800;
+ int21_ar[A][U][U][G][C][C][G] = 4.800;
+ int21_ar[A][U][U][G][G][C][G] = 4.800;
+ int21_ar[A][U][U][G][U][C][G] = 4.800;
+ int21_ar[A][U][U][U][A][C][G] = 4.800;
+ int21_ar[A][U][U][U][C][C][G] = 2.500;
+ int21_ar[A][U][U][U][G][C][G] = 4.800;
+ int21_ar[A][U][U][U][U][C][G] = 2.000;
+ int21_ar[A][U][A][A][A][G][C] = 3.200;
+ int21_ar[A][U][A][A][C][G][C] = 3.000;
+ int21_ar[A][U][A][A][G][G][C] = 2.400;
+ int21_ar[A][U][A][A][U][G][C] = 4.800;
+ int21_ar[A][U][A][C][A][G][C] = 2.900;
+ int21_ar[A][U][A][C][C][G][C] = 2.500;
+ int21_ar[A][U][A][C][G][G][C] = 2.400;
+ int21_ar[A][U][A][C][U][G][C] = 4.800;
+ int21_ar[A][U][A][G][A][G][C] = 1.800;
+ int21_ar[A][U][A][G][C][G][C] = 1.400;
+ int21_ar[A][U][A][G][G][G][C] = 1.200;
+ int21_ar[A][U][A][G][U][G][C] = 4.800;
+ int21_ar[A][U][A][U][A][G][C] = 4.800;
+ int21_ar[A][U][A][U][C][G][C] = 4.800;
+ int21_ar[A][U][A][U][G][G][C] = 4.800;
+ int21_ar[A][U][A][U][U][G][C] = 4.800;
+ int21_ar[A][U][C][A][A][G][C] = 3.100;
+ int21_ar[A][U][C][A][C][G][C] = 3.000;
+ int21_ar[A][U][C][A][G][G][C] = 4.800;
+ int21_ar[A][U][C][A][U][G][C] = 3.000;
+ int21_ar[A][U][C][C][A][G][C] = 3.000;
+ int21_ar[A][U][C][C][C][G][C] = 3.300;
+ int21_ar[A][U][C][C][G][G][C] = 4.800;
+ int21_ar[A][U][C][C][U][G][C] = 3.000;
+ int21_ar[A][U][C][G][A][G][C] = 4.800;
+ int21_ar[A][U][C][G][C][G][C] = 4.800;
+ int21_ar[A][U][C][G][G][G][C] = 4.800;
+ int21_ar[A][U][C][G][U][G][C] = 4.800;
+ int21_ar[A][U][C][U][A][G][C] = 3.300;
+ int21_ar[A][U][C][U][C][G][C] = 2.700;
+ int21_ar[A][U][C][U][G][G][C] = 4.800;
+ int21_ar[A][U][C][U][U][G][C] = 3.000;
+ int21_ar[A][U][G][A][A][G][C] = 2.500;
+ int21_ar[A][U][G][A][C][G][C] = 4.800;
+ int21_ar[A][U][G][A][G][G][C] = 1.600;
+ int21_ar[A][U][G][A][U][G][C] = 4.800;
+ int21_ar[A][U][G][C][A][G][C] = 4.800;
+ int21_ar[A][U][G][C][C][G][C] = 4.800;
+ int21_ar[A][U][G][C][G][G][C] = 4.800;
+ int21_ar[A][U][G][C][U][G][C] = 4.800;
+ int21_ar[A][U][G][G][A][G][C] = 1.600;
+ int21_ar[A][U][G][G][C][G][C] = 4.800;
+ int21_ar[A][U][G][G][G][G][C] = 3.000;
+ int21_ar[A][U][G][G][U][G][C] = 4.800;
+ int21_ar[A][U][G][U][A][G][C] = 4.800;
+ int21_ar[A][U][G][U][C][G][C] = 4.800;
+ int21_ar[A][U][G][U][G][G][C] = 4.800;
+ int21_ar[A][U][G][U][U][G][C] = 4.800;
+ int21_ar[A][U][U][A][A][G][C] = 4.800;
+ int21_ar[A][U][U][A][C][G][C] = 4.800;
+ int21_ar[A][U][U][A][G][G][C] = 4.800;
+ int21_ar[A][U][U][A][U][G][C] = 4.800;
+ int21_ar[A][U][U][C][A][G][C] = 4.800;
+ int21_ar[A][U][U][C][C][G][C] = 3.000;
+ int21_ar[A][U][U][C][G][G][C] = 4.800;
+ int21_ar[A][U][U][C][U][G][C] = 2.100;
+ int21_ar[A][U][U][G][A][G][C] = 4.800;
+ int21_ar[A][U][U][G][C][G][C] = 4.800;
+ int21_ar[A][U][U][G][G][G][C] = 4.800;
+ int21_ar[A][U][U][G][U][G][C] = 4.800;
+ int21_ar[A][U][U][U][A][G][C] = 4.800;
+ int21_ar[A][U][U][U][C][G][C] = 2.500;
+ int21_ar[A][U][U][U][G][G][C] = 4.800;
+ int21_ar[A][U][U][U][U][G][C] = 2.000;
+ int21_ar[A][U][A][A][A][G][U] = 3.900;
+ int21_ar[A][U][A][A][C][G][U] = 3.700;
+ int21_ar[A][U][A][A][G][G][U] = 3.100;
+ int21_ar[A][U][A][A][U][G][U] = 5.500;
+ int21_ar[A][U][A][C][A][G][U] = 3.600;
+ int21_ar[A][U][A][C][C][G][U] = 3.200;
+ int21_ar[A][U][A][C][G][G][U] = 3.100;
+ int21_ar[A][U][A][C][U][G][U] = 5.500;
+ int21_ar[A][U][A][G][A][G][U] = 2.500;
+ int21_ar[A][U][A][G][C][G][U] = 2.100;
+ int21_ar[A][U][A][G][G][G][U] = 1.900;
+ int21_ar[A][U][A][G][U][G][U] = 5.500;
+ int21_ar[A][U][A][U][A][G][U] = 5.500;
+ int21_ar[A][U][A][U][C][G][U] = 5.500;
+ int21_ar[A][U][A][U][G][G][U] = 5.500;
+ int21_ar[A][U][A][U][U][G][U] = 5.500;
+ int21_ar[A][U][C][A][A][G][U] = 3.800;
+ int21_ar[A][U][C][A][C][G][U] = 3.700;
+ int21_ar[A][U][C][A][G][G][U] = 5.500;
+ int21_ar[A][U][C][A][U][G][U] = 3.700;
+ int21_ar[A][U][C][C][A][G][U] = 3.700;
+ int21_ar[A][U][C][C][C][G][U] = 4.000;
+ int21_ar[A][U][C][C][G][G][U] = 5.500;
+ int21_ar[A][U][C][C][U][G][U] = 3.700;
+ int21_ar[A][U][C][G][A][G][U] = 5.500;
+ int21_ar[A][U][C][G][C][G][U] = 5.500;
+ int21_ar[A][U][C][G][G][G][U] = 5.500;
+ int21_ar[A][U][C][G][U][G][U] = 5.500;
+ int21_ar[A][U][C][U][A][G][U] = 4.000;
+ int21_ar[A][U][C][U][C][G][U] = 3.400;
+ int21_ar[A][U][C][U][G][G][U] = 5.500;
+ int21_ar[A][U][C][U][U][G][U] = 3.700;
+ int21_ar[A][U][G][A][A][G][U] = 3.200;
+ int21_ar[A][U][G][A][C][G][U] = 5.500;
+ int21_ar[A][U][G][A][G][G][U] = 2.300;
+ int21_ar[A][U][G][A][U][G][U] = 5.500;
+ int21_ar[A][U][G][C][A][G][U] = 5.500;
+ int21_ar[A][U][G][C][C][G][U] = 5.500;
+ int21_ar[A][U][G][C][G][G][U] = 5.500;
+ int21_ar[A][U][G][C][U][G][U] = 5.500;
+ int21_ar[A][U][G][G][A][G][U] = 2.300;
+ int21_ar[A][U][G][G][C][G][U] = 5.500;
+ int21_ar[A][U][G][G][G][G][U] = 3.700;
+ int21_ar[A][U][G][G][U][G][U] = 5.500;
+ int21_ar[A][U][G][U][A][G][U] = 5.500;
+ int21_ar[A][U][G][U][C][G][U] = 5.500;
+ int21_ar[A][U][G][U][G][G][U] = 5.500;
+ int21_ar[A][U][G][U][U][G][U] = 5.500;
+ int21_ar[A][U][U][A][A][G][U] = 5.500;
+ int21_ar[A][U][U][A][C][G][U] = 5.500;
+ int21_ar[A][U][U][A][G][G][U] = 5.500;
+ int21_ar[A][U][U][A][U][G][U] = 5.500;
+ int21_ar[A][U][U][C][A][G][U] = 5.500;
+ int21_ar[A][U][U][C][C][G][U] = 3.700;
+ int21_ar[A][U][U][C][G][G][U] = 5.500;
+ int21_ar[A][U][U][C][U][G][U] = 2.800;
+ int21_ar[A][U][U][G][A][G][U] = 5.500;
+ int21_ar[A][U][U][G][C][G][U] = 5.500;
+ int21_ar[A][U][U][G][G][G][U] = 5.500;
+ int21_ar[A][U][U][G][U][G][U] = 5.500;
+ int21_ar[A][U][U][U][A][G][U] = 5.500;
+ int21_ar[A][U][U][U][C][G][U] = 3.200;
+ int21_ar[A][U][U][U][G][G][U] = 5.500;
+ int21_ar[A][U][U][U][U][G][U] = 2.700;
+ int21_ar[A][U][A][A][A][U][A] = 3.900;
+ int21_ar[A][U][A][A][C][U][A] = 3.700;
+ int21_ar[A][U][A][A][G][U][A] = 3.100;
+ int21_ar[A][U][A][A][U][U][A] = 5.500;
+ int21_ar[A][U][A][C][A][U][A] = 3.600;
+ int21_ar[A][U][A][C][C][U][A] = 3.200;
+ int21_ar[A][U][A][C][G][U][A] = 3.100;
+ int21_ar[A][U][A][C][U][U][A] = 5.500;
+ int21_ar[A][U][A][G][A][U][A] = 2.500;
+ int21_ar[A][U][A][G][C][U][A] = 2.100;
+ int21_ar[A][U][A][G][G][U][A] = 1.900;
+ int21_ar[A][U][A][G][U][U][A] = 5.500;
+ int21_ar[A][U][A][U][A][U][A] = 5.500;
+ int21_ar[A][U][A][U][C][U][A] = 5.500;
+ int21_ar[A][U][A][U][G][U][A] = 5.500;
+ int21_ar[A][U][A][U][U][U][A] = 5.500;
+ int21_ar[A][U][C][A][A][U][A] = 3.800;
+ int21_ar[A][U][C][A][C][U][A] = 3.700;
+ int21_ar[A][U][C][A][G][U][A] = 5.500;
+ int21_ar[A][U][C][A][U][U][A] = 3.700;
+ int21_ar[A][U][C][C][A][U][A] = 3.700;
+ int21_ar[A][U][C][C][C][U][A] = 4.000;
+ int21_ar[A][U][C][C][G][U][A] = 5.500;
+ int21_ar[A][U][C][C][U][U][A] = 3.700;
+ int21_ar[A][U][C][G][A][U][A] = 5.500;
+ int21_ar[A][U][C][G][C][U][A] = 5.500;
+ int21_ar[A][U][C][G][G][U][A] = 5.500;
+ int21_ar[A][U][C][G][U][U][A] = 5.500;
+ int21_ar[A][U][C][U][A][U][A] = 4.000;
+ int21_ar[A][U][C][U][C][U][A] = 3.400;
+ int21_ar[A][U][C][U][G][U][A] = 5.500;
+ int21_ar[A][U][C][U][U][U][A] = 3.700;
+ int21_ar[A][U][G][A][A][U][A] = 3.200;
+ int21_ar[A][U][G][A][C][U][A] = 5.500;
+ int21_ar[A][U][G][A][G][U][A] = 2.300;
+ int21_ar[A][U][G][A][U][U][A] = 5.500;
+ int21_ar[A][U][G][C][A][U][A] = 5.500;
+ int21_ar[A][U][G][C][C][U][A] = 5.500;
+ int21_ar[A][U][G][C][G][U][A] = 5.500;
+ int21_ar[A][U][G][C][U][U][A] = 5.500;
+ int21_ar[A][U][G][G][A][U][A] = 2.300;
+ int21_ar[A][U][G][G][C][U][A] = 5.500;
+ int21_ar[A][U][G][G][G][U][A] = 3.700;
+ int21_ar[A][U][G][G][U][U][A] = 5.500;
+ int21_ar[A][U][G][U][A][U][A] = 5.500;
+ int21_ar[A][U][G][U][C][U][A] = 5.500;
+ int21_ar[A][U][G][U][G][U][A] = 5.500;
+ int21_ar[A][U][G][U][U][U][A] = 5.500;
+ int21_ar[A][U][U][A][A][U][A] = 5.500;
+ int21_ar[A][U][U][A][C][U][A] = 5.500;
+ int21_ar[A][U][U][A][G][U][A] = 5.500;
+ int21_ar[A][U][U][A][U][U][A] = 5.500;
+ int21_ar[A][U][U][C][A][U][A] = 5.500;
+ int21_ar[A][U][U][C][C][U][A] = 3.700;
+ int21_ar[A][U][U][C][G][U][A] = 5.500;
+ int21_ar[A][U][U][C][U][U][A] = 2.800;
+ int21_ar[A][U][U][G][A][U][A] = 5.500;
+ int21_ar[A][U][U][G][C][U][A] = 5.500;
+ int21_ar[A][U][U][G][G][U][A] = 5.500;
+ int21_ar[A][U][U][G][U][U][A] = 5.500;
+ int21_ar[A][U][U][U][A][U][A] = 5.500;
+ int21_ar[A][U][U][U][C][U][A] = 3.200;
+ int21_ar[A][U][U][U][G][U][A] = 5.500;
+ int21_ar[A][U][U][U][U][U][A] = 2.700;
+ int21_ar[A][U][A][A][A][U][G] = 3.900;
+ int21_ar[A][U][A][A][C][U][G] = 3.700;
+ int21_ar[A][U][A][A][G][U][G] = 3.100;
+ int21_ar[A][U][A][A][U][U][G] = 5.500;
+ int21_ar[A][U][A][C][A][U][G] = 3.600;
+ int21_ar[A][U][A][C][C][U][G] = 3.200;
+ int21_ar[A][U][A][C][G][U][G] = 3.100;
+ int21_ar[A][U][A][C][U][U][G] = 5.500;
+ int21_ar[A][U][A][G][A][U][G] = 2.500;
+ int21_ar[A][U][A][G][C][U][G] = 2.100;
+ int21_ar[A][U][A][G][G][U][G] = 1.900;
+ int21_ar[A][U][A][G][U][U][G] = 5.500;
+ int21_ar[A][U][A][U][A][U][G] = 5.500;
+ int21_ar[A][U][A][U][C][U][G] = 5.500;
+ int21_ar[A][U][A][U][G][U][G] = 5.500;
+ int21_ar[A][U][A][U][U][U][G] = 5.500;
+ int21_ar[A][U][C][A][A][U][G] = 3.800;
+ int21_ar[A][U][C][A][C][U][G] = 3.700;
+ int21_ar[A][U][C][A][G][U][G] = 5.500;
+ int21_ar[A][U][C][A][U][U][G] = 3.700;
+ int21_ar[A][U][C][C][A][U][G] = 3.700;
+ int21_ar[A][U][C][C][C][U][G] = 4.000;
+ int21_ar[A][U][C][C][G][U][G] = 5.500;
+ int21_ar[A][U][C][C][U][U][G] = 3.700;
+ int21_ar[A][U][C][G][A][U][G] = 5.500;
+ int21_ar[A][U][C][G][C][U][G] = 5.500;
+ int21_ar[A][U][C][G][G][U][G] = 5.500;
+ int21_ar[A][U][C][G][U][U][G] = 5.500;
+ int21_ar[A][U][C][U][A][U][G] = 4.000;
+ int21_ar[A][U][C][U][C][U][G] = 3.400;
+ int21_ar[A][U][C][U][G][U][G] = 5.500;
+ int21_ar[A][U][C][U][U][U][G] = 3.700;
+ int21_ar[A][U][G][A][A][U][G] = 3.200;
+ int21_ar[A][U][G][A][C][U][G] = 5.500;
+ int21_ar[A][U][G][A][G][U][G] = 2.300;
+ int21_ar[A][U][G][A][U][U][G] = 5.500;
+ int21_ar[A][U][G][C][A][U][G] = 5.500;
+ int21_ar[A][U][G][C][C][U][G] = 5.500;
+ int21_ar[A][U][G][C][G][U][G] = 5.500;
+ int21_ar[A][U][G][C][U][U][G] = 5.500;
+ int21_ar[A][U][G][G][A][U][G] = 2.300;
+ int21_ar[A][U][G][G][C][U][G] = 5.500;
+ int21_ar[A][U][G][G][G][U][G] = 3.700;
+ int21_ar[A][U][G][G][U][U][G] = 5.500;
+ int21_ar[A][U][G][U][A][U][G] = 5.500;
+ int21_ar[A][U][G][U][C][U][G] = 5.500;
+ int21_ar[A][U][G][U][G][U][G] = 5.500;
+ int21_ar[A][U][G][U][U][U][G] = 5.500;
+ int21_ar[A][U][U][A][A][U][G] = 5.500;
+ int21_ar[A][U][U][A][C][U][G] = 5.500;
+ int21_ar[A][U][U][A][G][U][G] = 5.500;
+ int21_ar[A][U][U][A][U][U][G] = 5.500;
+ int21_ar[A][U][U][C][A][U][G] = 5.500;
+ int21_ar[A][U][U][C][C][U][G] = 3.700;
+ int21_ar[A][U][U][C][G][U][G] = 5.500;
+ int21_ar[A][U][U][C][U][U][G] = 2.800;
+ int21_ar[A][U][U][G][A][U][G] = 5.500;
+ int21_ar[A][U][U][G][C][U][G] = 5.500;
+ int21_ar[A][U][U][G][G][U][G] = 5.500;
+ int21_ar[A][U][U][G][U][U][G] = 5.500;
+ int21_ar[A][U][U][U][A][U][G] = 5.500;
+ int21_ar[A][U][U][U][C][U][G] = 3.200;
+ int21_ar[A][U][U][U][G][U][G] = 5.500;
+ int21_ar[A][U][U][U][U][U][G] = 2.700;
+ int21_ar[C][G][A][A][A][A][U] = 3.200;
+ int21_ar[C][G][A][A][C][A][U] = 3.000;
+ int21_ar[C][G][A][A][G][A][U] = 2.400;
+ int21_ar[C][G][A][A][U][A][U] = 4.800;
+ int21_ar[C][G][A][C][A][A][U] = 2.900;
+ int21_ar[C][G][A][C][C][A][U] = 2.500;
+ int21_ar[C][G][A][C][G][A][U] = 2.400;
+ int21_ar[C][G][A][C][U][A][U] = 4.800;
+ int21_ar[C][G][A][G][A][A][U] = 1.800;
+ int21_ar[C][G][A][G][C][A][U] = 1.400;
+ int21_ar[C][G][A][G][G][A][U] = 1.200;
+ int21_ar[C][G][A][G][U][A][U] = 4.800;
+ int21_ar[C][G][A][U][A][A][U] = 4.800;
+ int21_ar[C][G][A][U][C][A][U] = 4.800;
+ int21_ar[C][G][A][U][G][A][U] = 4.800;
+ int21_ar[C][G][A][U][U][A][U] = 4.800;
+ int21_ar[C][G][C][A][A][A][U] = 3.100;
+ int21_ar[C][G][C][A][C][A][U] = 3.000;
+ int21_ar[C][G][C][A][G][A][U] = 4.800;
+ int21_ar[C][G][C][A][U][A][U] = 3.000;
+ int21_ar[C][G][C][C][A][A][U] = 3.000;
+ int21_ar[C][G][C][C][C][A][U] = 3.300;
+ int21_ar[C][G][C][C][G][A][U] = 4.800;
+ int21_ar[C][G][C][C][U][A][U] = 3.000;
+ int21_ar[C][G][C][G][A][A][U] = 4.800;
+ int21_ar[C][G][C][G][C][A][U] = 4.800;
+ int21_ar[C][G][C][G][G][A][U] = 4.800;
+ int21_ar[C][G][C][G][U][A][U] = 4.800;
+ int21_ar[C][G][C][U][A][A][U] = 3.300;
+ int21_ar[C][G][C][U][C][A][U] = 2.700;
+ int21_ar[C][G][C][U][G][A][U] = 4.800;
+ int21_ar[C][G][C][U][U][A][U] = 3.000;
+ int21_ar[C][G][G][A][A][A][U] = 2.500;
+ int21_ar[C][G][G][A][C][A][U] = 4.800;
+ int21_ar[C][G][G][A][G][A][U] = 1.600;
+ int21_ar[C][G][G][A][U][A][U] = 4.800;
+ int21_ar[C][G][G][C][A][A][U] = 4.800;
+ int21_ar[C][G][G][C][C][A][U] = 4.800;
+ int21_ar[C][G][G][C][G][A][U] = 4.800;
+ int21_ar[C][G][G][C][U][A][U] = 4.800;
+ int21_ar[C][G][G][G][A][A][U] = 1.600;
+ int21_ar[C][G][G][G][C][A][U] = 4.800;
+ int21_ar[C][G][G][G][G][A][U] = 3.000;
+ int21_ar[C][G][G][G][U][A][U] = 4.800;
+ int21_ar[C][G][G][U][A][A][U] = 4.800;
+ int21_ar[C][G][G][U][C][A][U] = 4.800;
+ int21_ar[C][G][G][U][G][A][U] = 4.800;
+ int21_ar[C][G][G][U][U][A][U] = 4.800;
+ int21_ar[C][G][U][A][A][A][U] = 4.800;
+ int21_ar[C][G][U][A][C][A][U] = 4.800;
+ int21_ar[C][G][U][A][G][A][U] = 4.800;
+ int21_ar[C][G][U][A][U][A][U] = 4.800;
+ int21_ar[C][G][U][C][A][A][U] = 4.800;
+ int21_ar[C][G][U][C][C][A][U] = 3.000;
+ int21_ar[C][G][U][C][G][A][U] = 4.800;
+ int21_ar[C][G][U][C][U][A][U] = 2.100;
+ int21_ar[C][G][U][G][A][A][U] = 4.800;
+ int21_ar[C][G][U][G][C][A][U] = 4.800;
+ int21_ar[C][G][U][G][G][A][U] = 4.800;
+ int21_ar[C][G][U][G][U][A][U] = 4.800;
+ int21_ar[C][G][U][U][A][A][U] = 4.800;
+ int21_ar[C][G][U][U][C][A][U] = 2.500;
+ int21_ar[C][G][U][U][G][A][U] = 4.800;
+ int21_ar[C][G][U][U][U][A][U] = 2.000;
+ int21_ar[C][G][A][A][A][C][G] = 2.400;
+ int21_ar[C][G][A][A][C][C][G] = 2.200;
+ int21_ar[C][G][A][A][G][C][G] = 1.600;
+ int21_ar[C][G][A][A][U][C][G] = 4.000;
+ int21_ar[C][G][A][C][A][C][G] = 2.100;
+ int21_ar[C][G][A][C][C][C][G] = 1.700;
+ int21_ar[C][G][A][C][G][C][G] = 1.600;
+ int21_ar[C][G][A][C][U][C][G] = 4.000;
+ int21_ar[C][G][A][G][A][C][G] = 1.000;
+ int21_ar[C][G][A][G][C][C][G] = 0.600;
+ int21_ar[C][G][A][G][G][C][G] = 0.400;
+ int21_ar[C][G][A][G][U][C][G] = 4.000;
+ int21_ar[C][G][A][U][A][C][G] = 4.000;
+ int21_ar[C][G][A][U][C][C][G] = 4.000;
+ int21_ar[C][G][A][U][G][C][G] = 4.000;
+ int21_ar[C][G][A][U][U][C][G] = 4.000;
+ int21_ar[C][G][C][A][A][C][G] = 2.300;
+ int21_ar[C][G][C][A][C][C][G] = 2.200;
+ int21_ar[C][G][C][A][G][C][G] = 4.000;
+ int21_ar[C][G][C][A][U][C][G] = 2.200;
+ int21_ar[C][G][C][C][A][C][G] = 2.200;
+ int21_ar[C][G][C][C][C][C][G] = 2.500;
+ int21_ar[C][G][C][C][G][C][G] = 4.000;
+ int21_ar[C][G][C][C][U][C][G] = 2.200;
+ int21_ar[C][G][C][G][A][C][G] = 4.000;
+ int21_ar[C][G][C][G][C][C][G] = 4.000;
+ int21_ar[C][G][C][G][G][C][G] = 4.000;
+ int21_ar[C][G][C][G][U][C][G] = 4.000;
+ int21_ar[C][G][C][U][A][C][G] = 2.500;
+ int21_ar[C][G][C][U][C][C][G] = 1.900;
+ int21_ar[C][G][C][U][G][C][G] = 4.000;
+ int21_ar[C][G][C][U][U][C][G] = 2.200;
+ int21_ar[C][G][G][A][A][C][G] = 1.700;
+ int21_ar[C][G][G][A][C][C][G] = 4.000;
+ int21_ar[C][G][G][A][G][C][G] = 0.800;
+ int21_ar[C][G][G][A][U][C][G] = 4.000;
+ int21_ar[C][G][G][C][A][C][G] = 4.000;
+ int21_ar[C][G][G][C][C][C][G] = 4.000;
+ int21_ar[C][G][G][C][G][C][G] = 4.000;
+ int21_ar[C][G][G][C][U][C][G] = 4.000;
+ int21_ar[C][G][G][G][A][C][G] = 0.800;
+ int21_ar[C][G][G][G][C][C][G] = 4.000;
+ int21_ar[C][G][G][G][G][C][G] = 2.200;
+ int21_ar[C][G][G][G][U][C][G] = 4.000;
+ int21_ar[C][G][G][U][A][C][G] = 4.000;
+ int21_ar[C][G][G][U][C][C][G] = 4.000;
+ int21_ar[C][G][G][U][G][C][G] = 4.000;
+ int21_ar[C][G][G][U][U][C][G] = 4.000;
+ int21_ar[C][G][U][A][A][C][G] = 4.000;
+ int21_ar[C][G][U][A][C][C][G] = 4.000;
+ int21_ar[C][G][U][A][G][C][G] = 4.000;
+ int21_ar[C][G][U][A][U][C][G] = 4.000;
+ int21_ar[C][G][U][C][A][C][G] = 4.000;
+ int21_ar[C][G][U][C][C][C][G] = 2.200;
+ int21_ar[C][G][U][C][G][C][G] = 4.000;
+ int21_ar[C][G][U][C][U][C][G] = 1.300;
+ int21_ar[C][G][U][G][A][C][G] = 4.000;
+ int21_ar[C][G][U][G][C][C][G] = 4.000;
+ int21_ar[C][G][U][G][G][C][G] = 4.000;
+ int21_ar[C][G][U][G][U][C][G] = 4.000;
+ int21_ar[C][G][U][U][A][C][G] = 4.000;
+ int21_ar[C][G][U][U][C][C][G] = 1.700;
+ int21_ar[C][G][U][U][G][C][G] = 4.000;
+ int21_ar[C][G][U][U][U][C][G] = 1.200;
+ int21_ar[C][G][A][A][A][G][C] = 2.300;
+ int21_ar[C][G][A][A][C][G][C] = 2.200;
+ int21_ar[C][G][A][A][G][G][C] = 1.100;
+ int21_ar[C][G][A][A][U][G][C] = 4.000;
+ int21_ar[C][G][A][C][A][G][C] = 2.100;
+ int21_ar[C][G][A][C][C][G][C] = 1.700;
+ int21_ar[C][G][A][C][G][G][C] = 1.600;
+ int21_ar[C][G][A][C][U][G][C] = 4.000;
+ int21_ar[C][G][A][G][A][G][C] = 0.800;
+ int21_ar[C][G][A][G][C][G][C] = 0.600;
+ int21_ar[C][G][A][G][G][G][C] = 0.400;
+ int21_ar[C][G][A][G][U][G][C] = 4.000;
+ int21_ar[C][G][A][U][A][G][C] = 4.000;
+ int21_ar[C][G][A][U][C][G][C] = 4.000;
+ int21_ar[C][G][A][U][G][G][C] = 4.000;
+ int21_ar[C][G][A][U][U][G][C] = 4.000;
+ int21_ar[C][G][C][A][A][G][C] = 2.300;
+ int21_ar[C][G][C][A][C][G][C] = 2.200;
+ int21_ar[C][G][C][A][G][G][C] = 4.000;
+ int21_ar[C][G][C][A][U][G][C] = 2.200;
+ int21_ar[C][G][C][C][A][G][C] = 2.200;
+ int21_ar[C][G][C][C][C][G][C] = 2.500;
+ int21_ar[C][G][C][C][G][G][C] = 4.000;
+ int21_ar[C][G][C][C][U][G][C] = 2.200;
+ int21_ar[C][G][C][G][A][G][C] = 4.000;
+ int21_ar[C][G][C][G][C][G][C] = 4.000;
+ int21_ar[C][G][C][G][G][G][C] = 4.000;
+ int21_ar[C][G][C][G][U][G][C] = 4.000;
+ int21_ar[C][G][C][U][A][G][C] = 2.500;
+ int21_ar[C][G][C][U][C][G][C] = 1.900;
+ int21_ar[C][G][C][U][G][G][C] = 4.000;
+ int21_ar[C][G][C][U][U][G][C] = 2.200;
+ int21_ar[C][G][G][A][A][G][C] = 1.700;
+ int21_ar[C][G][G][A][C][G][C] = 4.000;
+ int21_ar[C][G][G][A][G][G][C] = 0.800;
+ int21_ar[C][G][G][A][U][G][C] = 4.000;
+ int21_ar[C][G][G][C][A][G][C] = 4.000;
+ int21_ar[C][G][G][C][C][G][C] = 4.000;
+ int21_ar[C][G][G][C][G][G][C] = 4.000;
+ int21_ar[C][G][G][C][U][G][C] = 4.000;
+ int21_ar[C][G][G][G][A][G][C] = 0.800;
+ int21_ar[C][G][G][G][C][G][C] = 4.000;
+ int21_ar[C][G][G][G][G][G][C] = 2.200;
+ int21_ar[C][G][G][G][U][G][C] = 4.000;
+ int21_ar[C][G][G][U][A][G][C] = 4.000;
+ int21_ar[C][G][G][U][C][G][C] = 4.000;
+ int21_ar[C][G][G][U][G][G][C] = 4.000;
+ int21_ar[C][G][G][U][U][G][C] = 4.000;
+ int21_ar[C][G][U][A][A][G][C] = 4.000;
+ int21_ar[C][G][U][A][C][G][C] = 4.000;
+ int21_ar[C][G][U][A][G][G][C] = 4.000;
+ int21_ar[C][G][U][A][U][G][C] = 4.000;
+ int21_ar[C][G][U][C][A][G][C] = 4.000;
+ int21_ar[C][G][U][C][C][G][C] = 2.200;
+ int21_ar[C][G][U][C][G][G][C] = 4.000;
+ int21_ar[C][G][U][C][U][G][C] = 1.500;
+ int21_ar[C][G][U][G][A][G][C] = 4.000;
+ int21_ar[C][G][U][G][C][G][C] = 4.000;
+ int21_ar[C][G][U][G][G][G][C] = 4.000;
+ int21_ar[C][G][U][G][U][G][C] = 4.000;
+ int21_ar[C][G][U][U][A][G][C] = 4.000;
+ int21_ar[C][G][U][U][C][G][C] = 1.700;
+ int21_ar[C][G][U][U][G][G][C] = 4.000;
+ int21_ar[C][G][U][U][U][G][C] = 1.200;
+ int21_ar[C][G][A][A][A][G][U] = 3.200;
+ int21_ar[C][G][A][A][C][G][U] = 3.000;
+ int21_ar[C][G][A][A][G][G][U] = 2.400;
+ int21_ar[C][G][A][A][U][G][U] = 4.800;
+ int21_ar[C][G][A][C][A][G][U] = 2.900;
+ int21_ar[C][G][A][C][C][G][U] = 2.500;
+ int21_ar[C][G][A][C][G][G][U] = 2.400;
+ int21_ar[C][G][A][C][U][G][U] = 4.800;
+ int21_ar[C][G][A][G][A][G][U] = 1.800;
+ int21_ar[C][G][A][G][C][G][U] = 1.400;
+ int21_ar[C][G][A][G][G][G][U] = 1.200;
+ int21_ar[C][G][A][G][U][G][U] = 4.800;
+ int21_ar[C][G][A][U][A][G][U] = 4.800;
+ int21_ar[C][G][A][U][C][G][U] = 4.800;
+ int21_ar[C][G][A][U][G][G][U] = 4.800;
+ int21_ar[C][G][A][U][U][G][U] = 4.800;
+ int21_ar[C][G][C][A][A][G][U] = 3.100;
+ int21_ar[C][G][C][A][C][G][U] = 3.000;
+ int21_ar[C][G][C][A][G][G][U] = 4.800;
+ int21_ar[C][G][C][A][U][G][U] = 3.000;
+ int21_ar[C][G][C][C][A][G][U] = 3.000;
+ int21_ar[C][G][C][C][C][G][U] = 3.300;
+ int21_ar[C][G][C][C][G][G][U] = 4.800;
+ int21_ar[C][G][C][C][U][G][U] = 3.000;
+ int21_ar[C][G][C][G][A][G][U] = 4.800;
+ int21_ar[C][G][C][G][C][G][U] = 4.800;
+ int21_ar[C][G][C][G][G][G][U] = 4.800;
+ int21_ar[C][G][C][G][U][G][U] = 4.800;
+ int21_ar[C][G][C][U][A][G][U] = 3.300;
+ int21_ar[C][G][C][U][C][G][U] = 2.700;
+ int21_ar[C][G][C][U][G][G][U] = 4.800;
+ int21_ar[C][G][C][U][U][G][U] = 3.000;
+ int21_ar[C][G][G][A][A][G][U] = 2.500;
+ int21_ar[C][G][G][A][C][G][U] = 4.800;
+ int21_ar[C][G][G][A][G][G][U] = 1.600;
+ int21_ar[C][G][G][A][U][G][U] = 4.800;
+ int21_ar[C][G][G][C][A][G][U] = 4.800;
+ int21_ar[C][G][G][C][C][G][U] = 4.800;
+ int21_ar[C][G][G][C][G][G][U] = 4.800;
+ int21_ar[C][G][G][C][U][G][U] = 4.800;
+ int21_ar[C][G][G][G][A][G][U] = 1.600;
+ int21_ar[C][G][G][G][C][G][U] = 4.800;
+ int21_ar[C][G][G][G][G][G][U] = 3.000;
+ int21_ar[C][G][G][G][U][G][U] = 4.800;
+ int21_ar[C][G][G][U][A][G][U] = 4.800;
+ int21_ar[C][G][G][U][C][G][U] = 4.800;
+ int21_ar[C][G][G][U][G][G][U] = 4.800;
+ int21_ar[C][G][G][U][U][G][U] = 4.800;
+ int21_ar[C][G][U][A][A][G][U] = 4.800;
+ int21_ar[C][G][U][A][C][G][U] = 4.800;
+ int21_ar[C][G][U][A][G][G][U] = 4.800;
+ int21_ar[C][G][U][A][U][G][U] = 4.800;
+ int21_ar[C][G][U][C][A][G][U] = 4.800;
+ int21_ar[C][G][U][C][C][G][U] = 3.000;
+ int21_ar[C][G][U][C][G][G][U] = 4.800;
+ int21_ar[C][G][U][C][U][G][U] = 2.100;
+ int21_ar[C][G][U][G][A][G][U] = 4.800;
+ int21_ar[C][G][U][G][C][G][U] = 4.800;
+ int21_ar[C][G][U][G][G][G][U] = 4.800;
+ int21_ar[C][G][U][G][U][G][U] = 4.800;
+ int21_ar[C][G][U][U][A][G][U] = 4.800;
+ int21_ar[C][G][U][U][C][G][U] = 2.500;
+ int21_ar[C][G][U][U][G][G][U] = 4.800;
+ int21_ar[C][G][U][U][U][G][U] = 2.000;
+ int21_ar[C][G][A][A][A][U][A] = 3.200;
+ int21_ar[C][G][A][A][C][U][A] = 3.000;
+ int21_ar[C][G][A][A][G][U][A] = 2.400;
+ int21_ar[C][G][A][A][U][U][A] = 4.800;
+ int21_ar[C][G][A][C][A][U][A] = 2.900;
+ int21_ar[C][G][A][C][C][U][A] = 2.500;
+ int21_ar[C][G][A][C][G][U][A] = 2.400;
+ int21_ar[C][G][A][C][U][U][A] = 4.800;
+ int21_ar[C][G][A][G][A][U][A] = 1.800;
+ int21_ar[C][G][A][G][C][U][A] = 1.400;
+ int21_ar[C][G][A][G][G][U][A] = 1.200;
+ int21_ar[C][G][A][G][U][U][A] = 4.800;
+ int21_ar[C][G][A][U][A][U][A] = 4.800;
+ int21_ar[C][G][A][U][C][U][A] = 4.800;
+ int21_ar[C][G][A][U][G][U][A] = 4.800;
+ int21_ar[C][G][A][U][U][U][A] = 4.800;
+ int21_ar[C][G][C][A][A][U][A] = 3.100;
+ int21_ar[C][G][C][A][C][U][A] = 3.000;
+ int21_ar[C][G][C][A][G][U][A] = 4.800;
+ int21_ar[C][G][C][A][U][U][A] = 3.000;
+ int21_ar[C][G][C][C][A][U][A] = 3.000;
+ int21_ar[C][G][C][C][C][U][A] = 3.300;
+ int21_ar[C][G][C][C][G][U][A] = 4.800;
+ int21_ar[C][G][C][C][U][U][A] = 3.000;
+ int21_ar[C][G][C][G][A][U][A] = 4.800;
+ int21_ar[C][G][C][G][C][U][A] = 4.800;
+ int21_ar[C][G][C][G][G][U][A] = 4.800;
+ int21_ar[C][G][C][G][U][U][A] = 4.800;
+ int21_ar[C][G][C][U][A][U][A] = 3.300;
+ int21_ar[C][G][C][U][C][U][A] = 2.700;
+ int21_ar[C][G][C][U][G][U][A] = 4.800;
+ int21_ar[C][G][C][U][U][U][A] = 3.000;
+ int21_ar[C][G][G][A][A][U][A] = 2.500;
+ int21_ar[C][G][G][A][C][U][A] = 4.800;
+ int21_ar[C][G][G][A][G][U][A] = 1.600;
+ int21_ar[C][G][G][A][U][U][A] = 4.800;
+ int21_ar[C][G][G][C][A][U][A] = 4.800;
+ int21_ar[C][G][G][C][C][U][A] = 4.800;
+ int21_ar[C][G][G][C][G][U][A] = 4.800;
+ int21_ar[C][G][G][C][U][U][A] = 4.800;
+ int21_ar[C][G][G][G][A][U][A] = 1.600;
+ int21_ar[C][G][G][G][C][U][A] = 4.800;
+ int21_ar[C][G][G][G][G][U][A] = 3.000;
+ int21_ar[C][G][G][G][U][U][A] = 4.800;
+ int21_ar[C][G][G][U][A][U][A] = 4.800;
+ int21_ar[C][G][G][U][C][U][A] = 4.800;
+ int21_ar[C][G][G][U][G][U][A] = 4.800;
+ int21_ar[C][G][G][U][U][U][A] = 4.800;
+ int21_ar[C][G][U][A][A][U][A] = 4.800;
+ int21_ar[C][G][U][A][C][U][A] = 4.800;
+ int21_ar[C][G][U][A][G][U][A] = 4.800;
+ int21_ar[C][G][U][A][U][U][A] = 4.800;
+ int21_ar[C][G][U][C][A][U][A] = 4.800;
+ int21_ar[C][G][U][C][C][U][A] = 3.000;
+ int21_ar[C][G][U][C][G][U][A] = 4.800;
+ int21_ar[C][G][U][C][U][U][A] = 2.100;
+ int21_ar[C][G][U][G][A][U][A] = 4.800;
+ int21_ar[C][G][U][G][C][U][A] = 4.800;
+ int21_ar[C][G][U][G][G][U][A] = 4.800;
+ int21_ar[C][G][U][G][U][U][A] = 4.800;
+ int21_ar[C][G][U][U][A][U][A] = 4.800;
+ int21_ar[C][G][U][U][C][U][A] = 2.500;
+ int21_ar[C][G][U][U][G][U][A] = 4.800;
+ int21_ar[C][G][U][U][U][U][A] = 2.000;
+ int21_ar[C][G][A][A][A][U][G] = 3.200;
+ int21_ar[C][G][A][A][C][U][G] = 3.000;
+ int21_ar[C][G][A][A][G][U][G] = 2.400;
+ int21_ar[C][G][A][A][U][U][G] = 4.800;
+ int21_ar[C][G][A][C][A][U][G] = 2.900;
+ int21_ar[C][G][A][C][C][U][G] = 2.500;
+ int21_ar[C][G][A][C][G][U][G] = 2.400;
+ int21_ar[C][G][A][C][U][U][G] = 4.800;
+ int21_ar[C][G][A][G][A][U][G] = 1.800;
+ int21_ar[C][G][A][G][C][U][G] = 1.400;
+ int21_ar[C][G][A][G][G][U][G] = 1.200;
+ int21_ar[C][G][A][G][U][U][G] = 4.800;
+ int21_ar[C][G][A][U][A][U][G] = 4.800;
+ int21_ar[C][G][A][U][C][U][G] = 4.800;
+ int21_ar[C][G][A][U][G][U][G] = 4.800;
+ int21_ar[C][G][A][U][U][U][G] = 4.800;
+ int21_ar[C][G][C][A][A][U][G] = 3.100;
+ int21_ar[C][G][C][A][C][U][G] = 3.000;
+ int21_ar[C][G][C][A][G][U][G] = 4.800;
+ int21_ar[C][G][C][A][U][U][G] = 3.000;
+ int21_ar[C][G][C][C][A][U][G] = 3.000;
+ int21_ar[C][G][C][C][C][U][G] = 3.300;
+ int21_ar[C][G][C][C][G][U][G] = 4.800;
+ int21_ar[C][G][C][C][U][U][G] = 3.000;
+ int21_ar[C][G][C][G][A][U][G] = 4.800;
+ int21_ar[C][G][C][G][C][U][G] = 4.800;
+ int21_ar[C][G][C][G][G][U][G] = 4.800;
+ int21_ar[C][G][C][G][U][U][G] = 4.800;
+ int21_ar[C][G][C][U][A][U][G] = 3.300;
+ int21_ar[C][G][C][U][C][U][G] = 2.700;
+ int21_ar[C][G][C][U][G][U][G] = 4.800;
+ int21_ar[C][G][C][U][U][U][G] = 3.000;
+ int21_ar[C][G][G][A][A][U][G] = 2.500;
+ int21_ar[C][G][G][A][C][U][G] = 4.800;
+ int21_ar[C][G][G][A][G][U][G] = 1.600;
+ int21_ar[C][G][G][A][U][U][G] = 4.800;
+ int21_ar[C][G][G][C][A][U][G] = 4.800;
+ int21_ar[C][G][G][C][C][U][G] = 4.800;
+ int21_ar[C][G][G][C][G][U][G] = 4.800;
+ int21_ar[C][G][G][C][U][U][G] = 4.800;
+ int21_ar[C][G][G][G][A][U][G] = 1.600;
+ int21_ar[C][G][G][G][C][U][G] = 4.800;
+ int21_ar[C][G][G][G][G][U][G] = 3.000;
+ int21_ar[C][G][G][G][U][U][G] = 4.800;
+ int21_ar[C][G][G][U][A][U][G] = 4.800;
+ int21_ar[C][G][G][U][C][U][G] = 4.800;
+ int21_ar[C][G][G][U][G][U][G] = 4.800;
+ int21_ar[C][G][G][U][U][U][G] = 4.800;
+ int21_ar[C][G][U][A][A][U][G] = 4.800;
+ int21_ar[C][G][U][A][C][U][G] = 4.800;
+ int21_ar[C][G][U][A][G][U][G] = 4.800;
+ int21_ar[C][G][U][A][U][U][G] = 4.800;
+ int21_ar[C][G][U][C][A][U][G] = 4.800;
+ int21_ar[C][G][U][C][C][U][G] = 3.000;
+ int21_ar[C][G][U][C][G][U][G] = 4.800;
+ int21_ar[C][G][U][C][U][U][G] = 2.100;
+ int21_ar[C][G][U][G][A][U][G] = 4.800;
+ int21_ar[C][G][U][G][C][U][G] = 4.800;
+ int21_ar[C][G][U][G][G][U][G] = 4.800;
+ int21_ar[C][G][U][G][U][U][G] = 4.800;
+ int21_ar[C][G][U][U][A][U][G] = 4.800;
+ int21_ar[C][G][U][U][C][U][G] = 2.500;
+ int21_ar[C][G][U][U][G][U][G] = 4.800;
+ int21_ar[C][G][U][U][U][U][G] = 2.000;
+ int21_ar[G][C][A][A][A][A][U] = 3.200;
+ int21_ar[G][C][A][A][C][A][U] = 3.000;
+ int21_ar[G][C][A][A][G][A][U] = 2.400;
+ int21_ar[G][C][A][A][U][A][U] = 4.800;
+ int21_ar[G][C][A][C][A][A][U] = 2.900;
+ int21_ar[G][C][A][C][C][A][U] = 2.500;
+ int21_ar[G][C][A][C][G][A][U] = 2.400;
+ int21_ar[G][C][A][C][U][A][U] = 4.800;
+ int21_ar[G][C][A][G][A][A][U] = 1.800;
+ int21_ar[G][C][A][G][C][A][U] = 1.400;
+ int21_ar[G][C][A][G][G][A][U] = 1.200;
+ int21_ar[G][C][A][G][U][A][U] = 4.800;
+ int21_ar[G][C][A][U][A][A][U] = 4.800;
+ int21_ar[G][C][A][U][C][A][U] = 4.800;
+ int21_ar[G][C][A][U][G][A][U] = 4.800;
+ int21_ar[G][C][A][U][U][A][U] = 4.800;
+ int21_ar[G][C][C][A][A][A][U] = 3.100;
+ int21_ar[G][C][C][A][C][A][U] = 3.000;
+ int21_ar[G][C][C][A][G][A][U] = 4.800;
+ int21_ar[G][C][C][A][U][A][U] = 3.000;
+ int21_ar[G][C][C][C][A][A][U] = 3.000;
+ int21_ar[G][C][C][C][C][A][U] = 3.300;
+ int21_ar[G][C][C][C][G][A][U] = 4.800;
+ int21_ar[G][C][C][C][U][A][U] = 3.000;
+ int21_ar[G][C][C][G][A][A][U] = 4.800;
+ int21_ar[G][C][C][G][C][A][U] = 4.800;
+ int21_ar[G][C][C][G][G][A][U] = 4.800;
+ int21_ar[G][C][C][G][U][A][U] = 4.800;
+ int21_ar[G][C][C][U][A][A][U] = 3.300;
+ int21_ar[G][C][C][U][C][A][U] = 2.700;
+ int21_ar[G][C][C][U][G][A][U] = 4.800;
+ int21_ar[G][C][C][U][U][A][U] = 3.000;
+ int21_ar[G][C][G][A][A][A][U] = 2.500;
+ int21_ar[G][C][G][A][C][A][U] = 4.800;
+ int21_ar[G][C][G][A][G][A][U] = 1.600;
+ int21_ar[G][C][G][A][U][A][U] = 4.800;
+ int21_ar[G][C][G][C][A][A][U] = 4.800;
+ int21_ar[G][C][G][C][C][A][U] = 4.800;
+ int21_ar[G][C][G][C][G][A][U] = 4.800;
+ int21_ar[G][C][G][C][U][A][U] = 4.800;
+ int21_ar[G][C][G][G][A][A][U] = 1.600;
+ int21_ar[G][C][G][G][C][A][U] = 4.800;
+ int21_ar[G][C][G][G][G][A][U] = 3.000;
+ int21_ar[G][C][G][G][U][A][U] = 4.800;
+ int21_ar[G][C][G][U][A][A][U] = 4.800;
+ int21_ar[G][C][G][U][C][A][U] = 4.800;
+ int21_ar[G][C][G][U][G][A][U] = 4.800;
+ int21_ar[G][C][G][U][U][A][U] = 4.800;
+ int21_ar[G][C][U][A][A][A][U] = 4.800;
+ int21_ar[G][C][U][A][C][A][U] = 4.800;
+ int21_ar[G][C][U][A][G][A][U] = 4.800;
+ int21_ar[G][C][U][A][U][A][U] = 4.800;
+ int21_ar[G][C][U][C][A][A][U] = 4.800;
+ int21_ar[G][C][U][C][C][A][U] = 3.000;
+ int21_ar[G][C][U][C][G][A][U] = 4.800;
+ int21_ar[G][C][U][C][U][A][U] = 2.100;
+ int21_ar[G][C][U][G][A][A][U] = 4.800;
+ int21_ar[G][C][U][G][C][A][U] = 4.800;
+ int21_ar[G][C][U][G][G][A][U] = 4.800;
+ int21_ar[G][C][U][G][U][A][U] = 4.800;
+ int21_ar[G][C][U][U][A][A][U] = 4.800;
+ int21_ar[G][C][U][U][C][A][U] = 2.500;
+ int21_ar[G][C][U][U][G][A][U] = 4.800;
+ int21_ar[G][C][U][U][U][A][U] = 2.000;
+ int21_ar[G][C][A][A][A][C][G] = 2.500;
+ int21_ar[G][C][A][A][C][C][G] = 2.200;
+ int21_ar[G][C][A][A][G][C][G] = 2.100;
+ int21_ar[G][C][A][A][U][C][G] = 4.000;
+ int21_ar[G][C][A][C][A][C][G] = 2.100;
+ int21_ar[G][C][A][C][C][C][G] = 1.700;
+ int21_ar[G][C][A][C][G][C][G] = 1.600;
+ int21_ar[G][C][A][C][U][C][G] = 4.000;
+ int21_ar[G][C][A][G][A][C][G] = 1.200;
+ int21_ar[G][C][A][G][C][C][G] = 0.600;
+ int21_ar[G][C][A][G][G][C][G] = 0.400;
+ int21_ar[G][C][A][G][U][C][G] = 4.000;
+ int21_ar[G][C][A][U][A][C][G] = 4.000;
+ int21_ar[G][C][A][U][C][C][G] = 4.000;
+ int21_ar[G][C][A][U][G][C][G] = 4.000;
+ int21_ar[G][C][A][U][U][C][G] = 4.000;
+ int21_ar[G][C][C][A][A][C][G] = 2.300;
+ int21_ar[G][C][C][A][C][C][G] = 2.200;
+ int21_ar[G][C][C][A][G][C][G] = 4.000;
+ int21_ar[G][C][C][A][U][C][G] = 2.200;
+ int21_ar[G][C][C][C][A][C][G] = 2.200;
+ int21_ar[G][C][C][C][C][C][G] = 2.500;
+ int21_ar[G][C][C][C][G][C][G] = 4.000;
+ int21_ar[G][C][C][C][U][C][G] = 2.200;
+ int21_ar[G][C][C][G][A][C][G] = 4.000;
+ int21_ar[G][C][C][G][C][C][G] = 4.000;
+ int21_ar[G][C][C][G][G][C][G] = 4.000;
+ int21_ar[G][C][C][G][U][C][G] = 4.000;
+ int21_ar[G][C][C][U][A][C][G] = 2.500;
+ int21_ar[G][C][C][U][C][C][G] = 1.900;
+ int21_ar[G][C][C][U][G][C][G] = 4.000;
+ int21_ar[G][C][C][U][U][C][G] = 2.200;
+ int21_ar[G][C][G][A][A][C][G] = 1.700;
+ int21_ar[G][C][G][A][C][C][G] = 4.000;
+ int21_ar[G][C][G][A][G][C][G] = 0.800;
+ int21_ar[G][C][G][A][U][C][G] = 4.000;
+ int21_ar[G][C][G][C][A][C][G] = 4.000;
+ int21_ar[G][C][G][C][C][C][G] = 4.000;
+ int21_ar[G][C][G][C][G][C][G] = 4.000;
+ int21_ar[G][C][G][C][U][C][G] = 4.000;
+ int21_ar[G][C][G][G][A][C][G] = 0.800;
+ int21_ar[G][C][G][G][C][C][G] = 4.000;
+ int21_ar[G][C][G][G][G][C][G] = 2.200;
+ int21_ar[G][C][G][G][U][C][G] = 4.000;
+ int21_ar[G][C][G][U][A][C][G] = 4.000;
+ int21_ar[G][C][G][U][C][C][G] = 4.000;
+ int21_ar[G][C][G][U][G][C][G] = 4.000;
+ int21_ar[G][C][G][U][U][C][G] = 4.000;
+ int21_ar[G][C][U][A][A][C][G] = 4.000;
+ int21_ar[G][C][U][A][C][C][G] = 4.000;
+ int21_ar[G][C][U][A][G][C][G] = 4.000;
+ int21_ar[G][C][U][A][U][C][G] = 4.000;
+ int21_ar[G][C][U][C][A][C][G] = 4.000;
+ int21_ar[G][C][U][C][C][C][G] = 2.200;
+ int21_ar[G][C][U][C][G][C][G] = 4.000;
+ int21_ar[G][C][U][C][U][C][G] = 1.200;
+ int21_ar[G][C][U][G][A][C][G] = 4.000;
+ int21_ar[G][C][U][G][C][C][G] = 4.000;
+ int21_ar[G][C][U][G][G][C][G] = 4.000;
+ int21_ar[G][C][U][G][U][C][G] = 4.000;
+ int21_ar[G][C][U][U][A][C][G] = 4.000;
+ int21_ar[G][C][U][U][C][C][G] = 1.700;
+ int21_ar[G][C][U][U][G][C][G] = 4.000;
+ int21_ar[G][C][U][U][U][C][G] = 1.200;
+ int21_ar[G][C][A][A][A][G][C] = 2.400;
+ int21_ar[G][C][A][A][C][G][C] = 2.200;
+ int21_ar[G][C][A][A][G][G][C] = 1.600;
+ int21_ar[G][C][A][A][U][G][C] = 4.000;
+ int21_ar[G][C][A][C][A][G][C] = 2.100;
+ int21_ar[G][C][A][C][C][G][C] = 1.700;
+ int21_ar[G][C][A][C][G][G][C] = 1.600;
+ int21_ar[G][C][A][C][U][G][C] = 4.000;
+ int21_ar[G][C][A][G][A][G][C] = 1.000;
+ int21_ar[G][C][A][G][C][G][C] = 0.600;
+ int21_ar[G][C][A][G][G][G][C] = 0.400;
+ int21_ar[G][C][A][G][U][G][C] = 4.000;
+ int21_ar[G][C][A][U][A][G][C] = 4.000;
+ int21_ar[G][C][A][U][C][G][C] = 4.000;
+ int21_ar[G][C][A][U][G][G][C] = 4.000;
+ int21_ar[G][C][A][U][U][G][C] = 4.000;
+ int21_ar[G][C][C][A][A][G][C] = 2.300;
+ int21_ar[G][C][C][A][C][G][C] = 2.200;
+ int21_ar[G][C][C][A][G][G][C] = 4.000;
+ int21_ar[G][C][C][A][U][G][C] = 2.200;
+ int21_ar[G][C][C][C][A][G][C] = 2.200;
+ int21_ar[G][C][C][C][C][G][C] = 2.500;
+ int21_ar[G][C][C][C][G][G][C] = 4.000;
+ int21_ar[G][C][C][C][U][G][C] = 2.200;
+ int21_ar[G][C][C][G][A][G][C] = 4.000;
+ int21_ar[G][C][C][G][C][G][C] = 4.000;
+ int21_ar[G][C][C][G][G][G][C] = 4.000;
+ int21_ar[G][C][C][G][U][G][C] = 4.000;
+ int21_ar[G][C][C][U][A][G][C] = 2.500;
+ int21_ar[G][C][C][U][C][G][C] = 1.900;
+ int21_ar[G][C][C][U][G][G][C] = 4.000;
+ int21_ar[G][C][C][U][U][G][C] = 2.200;
+ int21_ar[G][C][G][A][A][G][C] = 1.700;
+ int21_ar[G][C][G][A][C][G][C] = 4.000;
+ int21_ar[G][C][G][A][G][G][C] = 0.800;
+ int21_ar[G][C][G][A][U][G][C] = 4.000;
+ int21_ar[G][C][G][C][A][G][C] = 4.000;
+ int21_ar[G][C][G][C][C][G][C] = 4.000;
+ int21_ar[G][C][G][C][G][G][C] = 4.000;
+ int21_ar[G][C][G][C][U][G][C] = 4.000;
+ int21_ar[G][C][G][G][A][G][C] = 0.800;
+ int21_ar[G][C][G][G][C][G][C] = 4.000;
+ int21_ar[G][C][G][G][G][G][C] = 2.200;
+ int21_ar[G][C][G][G][U][G][C] = 4.000;
+ int21_ar[G][C][G][U][A][G][C] = 4.000;
+ int21_ar[G][C][G][U][C][G][C] = 4.000;
+ int21_ar[G][C][G][U][G][G][C] = 4.000;
+ int21_ar[G][C][G][U][U][G][C] = 4.000;
+ int21_ar[G][C][U][A][A][G][C] = 4.000;
+ int21_ar[G][C][U][A][C][G][C] = 4.000;
+ int21_ar[G][C][U][A][G][G][C] = 4.000;
+ int21_ar[G][C][U][A][U][G][C] = 4.000;
+ int21_ar[G][C][U][C][A][G][C] = 4.000;
+ int21_ar[G][C][U][C][C][G][C] = 2.200;
+ int21_ar[G][C][U][C][G][G][C] = 4.000;
+ int21_ar[G][C][U][C][U][G][C] = 1.300;
+ int21_ar[G][C][U][G][A][G][C] = 4.000;
+ int21_ar[G][C][U][G][C][G][C] = 4.000;
+ int21_ar[G][C][U][G][G][G][C] = 4.000;
+ int21_ar[G][C][U][G][U][G][C] = 4.000;
+ int21_ar[G][C][U][U][A][G][C] = 4.000;
+ int21_ar[G][C][U][U][C][G][C] = 1.700;
+ int21_ar[G][C][U][U][G][G][C] = 4.000;
+ int21_ar[G][C][U][U][U][G][C] = 1.200;
+ int21_ar[G][C][A][A][A][G][U] = 3.200;
+ int21_ar[G][C][A][A][C][G][U] = 3.000;
+ int21_ar[G][C][A][A][G][G][U] = 2.400;
+ int21_ar[G][C][A][A][U][G][U] = 4.800;
+ int21_ar[G][C][A][C][A][G][U] = 2.900;
+ int21_ar[G][C][A][C][C][G][U] = 2.500;
+ int21_ar[G][C][A][C][G][G][U] = 2.400;
+ int21_ar[G][C][A][C][U][G][U] = 4.800;
+ int21_ar[G][C][A][G][A][G][U] = 1.800;
+ int21_ar[G][C][A][G][C][G][U] = 1.400;
+ int21_ar[G][C][A][G][G][G][U] = 1.200;
+ int21_ar[G][C][A][G][U][G][U] = 4.800;
+ int21_ar[G][C][A][U][A][G][U] = 4.800;
+ int21_ar[G][C][A][U][C][G][U] = 4.800;
+ int21_ar[G][C][A][U][G][G][U] = 4.800;
+ int21_ar[G][C][A][U][U][G][U] = 4.800;
+ int21_ar[G][C][C][A][A][G][U] = 3.100;
+ int21_ar[G][C][C][A][C][G][U] = 3.000;
+ int21_ar[G][C][C][A][G][G][U] = 4.800;
+ int21_ar[G][C][C][A][U][G][U] = 3.000;
+ int21_ar[G][C][C][C][A][G][U] = 3.000;
+ int21_ar[G][C][C][C][C][G][U] = 3.300;
+ int21_ar[G][C][C][C][G][G][U] = 4.800;
+ int21_ar[G][C][C][C][U][G][U] = 3.000;
+ int21_ar[G][C][C][G][A][G][U] = 4.800;
+ int21_ar[G][C][C][G][C][G][U] = 4.800;
+ int21_ar[G][C][C][G][G][G][U] = 4.800;
+ int21_ar[G][C][C][G][U][G][U] = 4.800;
+ int21_ar[G][C][C][U][A][G][U] = 3.300;
+ int21_ar[G][C][C][U][C][G][U] = 2.700;
+ int21_ar[G][C][C][U][G][G][U] = 4.800;
+ int21_ar[G][C][C][U][U][G][U] = 3.000;
+ int21_ar[G][C][G][A][A][G][U] = 2.500;
+ int21_ar[G][C][G][A][C][G][U] = 4.800;
+ int21_ar[G][C][G][A][G][G][U] = 1.600;
+ int21_ar[G][C][G][A][U][G][U] = 4.800;
+ int21_ar[G][C][G][C][A][G][U] = 4.800;
+ int21_ar[G][C][G][C][C][G][U] = 4.800;
+ int21_ar[G][C][G][C][G][G][U] = 4.800;
+ int21_ar[G][C][G][C][U][G][U] = 4.800;
+ int21_ar[G][C][G][G][A][G][U] = 1.600;
+ int21_ar[G][C][G][G][C][G][U] = 4.800;
+ int21_ar[G][C][G][G][G][G][U] = 3.000;
+ int21_ar[G][C][G][G][U][G][U] = 4.800;
+ int21_ar[G][C][G][U][A][G][U] = 4.800;
+ int21_ar[G][C][G][U][C][G][U] = 4.800;
+ int21_ar[G][C][G][U][G][G][U] = 4.800;
+ int21_ar[G][C][G][U][U][G][U] = 4.800;
+ int21_ar[G][C][U][A][A][G][U] = 4.800;
+ int21_ar[G][C][U][A][C][G][U] = 4.800;
+ int21_ar[G][C][U][A][G][G][U] = 4.800;
+ int21_ar[G][C][U][A][U][G][U] = 4.800;
+ int21_ar[G][C][U][C][A][G][U] = 4.800;
+ int21_ar[G][C][U][C][C][G][U] = 3.000;
+ int21_ar[G][C][U][C][G][G][U] = 4.800;
+ int21_ar[G][C][U][C][U][G][U] = 2.100;
+ int21_ar[G][C][U][G][A][G][U] = 4.800;
+ int21_ar[G][C][U][G][C][G][U] = 4.800;
+ int21_ar[G][C][U][G][G][G][U] = 4.800;
+ int21_ar[G][C][U][G][U][G][U] = 4.800;
+ int21_ar[G][C][U][U][A][G][U] = 4.800;
+ int21_ar[G][C][U][U][C][G][U] = 2.500;
+ int21_ar[G][C][U][U][G][G][U] = 4.800;
+ int21_ar[G][C][U][U][U][G][U] = 2.000;
+ int21_ar[G][C][A][A][A][U][A] = 3.200;
+ int21_ar[G][C][A][A][C][U][A] = 3.000;
+ int21_ar[G][C][A][A][G][U][A] = 2.400;
+ int21_ar[G][C][A][A][U][U][A] = 4.800;
+ int21_ar[G][C][A][C][A][U][A] = 2.900;
+ int21_ar[G][C][A][C][C][U][A] = 2.500;
+ int21_ar[G][C][A][C][G][U][A] = 2.400;
+ int21_ar[G][C][A][C][U][U][A] = 4.800;
+ int21_ar[G][C][A][G][A][U][A] = 1.800;
+ int21_ar[G][C][A][G][C][U][A] = 1.400;
+ int21_ar[G][C][A][G][G][U][A] = 1.200;
+ int21_ar[G][C][A][G][U][U][A] = 4.800;
+ int21_ar[G][C][A][U][A][U][A] = 4.800;
+ int21_ar[G][C][A][U][C][U][A] = 4.800;
+ int21_ar[G][C][A][U][G][U][A] = 4.800;
+ int21_ar[G][C][A][U][U][U][A] = 4.800;
+ int21_ar[G][C][C][A][A][U][A] = 3.100;
+ int21_ar[G][C][C][A][C][U][A] = 3.000;
+ int21_ar[G][C][C][A][G][U][A] = 4.800;
+ int21_ar[G][C][C][A][U][U][A] = 3.000;
+ int21_ar[G][C][C][C][A][U][A] = 3.000;
+ int21_ar[G][C][C][C][C][U][A] = 3.300;
+ int21_ar[G][C][C][C][G][U][A] = 4.800;
+ int21_ar[G][C][C][C][U][U][A] = 3.000;
+ int21_ar[G][C][C][G][A][U][A] = 4.800;
+ int21_ar[G][C][C][G][C][U][A] = 4.800;
+ int21_ar[G][C][C][G][G][U][A] = 4.800;
+ int21_ar[G][C][C][G][U][U][A] = 4.800;
+ int21_ar[G][C][C][U][A][U][A] = 3.300;
+ int21_ar[G][C][C][U][C][U][A] = 2.700;
+ int21_ar[G][C][C][U][G][U][A] = 4.800;
+ int21_ar[G][C][C][U][U][U][A] = 3.000;
+ int21_ar[G][C][G][A][A][U][A] = 2.500;
+ int21_ar[G][C][G][A][C][U][A] = 4.800;
+ int21_ar[G][C][G][A][G][U][A] = 1.600;
+ int21_ar[G][C][G][A][U][U][A] = 4.800;
+ int21_ar[G][C][G][C][A][U][A] = 4.800;
+ int21_ar[G][C][G][C][C][U][A] = 4.800;
+ int21_ar[G][C][G][C][G][U][A] = 4.800;
+ int21_ar[G][C][G][C][U][U][A] = 4.800;
+ int21_ar[G][C][G][G][A][U][A] = 1.600;
+ int21_ar[G][C][G][G][C][U][A] = 4.800;
+ int21_ar[G][C][G][G][G][U][A] = 3.000;
+ int21_ar[G][C][G][G][U][U][A] = 4.800;
+ int21_ar[G][C][G][U][A][U][A] = 4.800;
+ int21_ar[G][C][G][U][C][U][A] = 4.800;
+ int21_ar[G][C][G][U][G][U][A] = 4.800;
+ int21_ar[G][C][G][U][U][U][A] = 4.800;
+ int21_ar[G][C][U][A][A][U][A] = 4.800;
+ int21_ar[G][C][U][A][C][U][A] = 4.800;
+ int21_ar[G][C][U][A][G][U][A] = 4.800;
+ int21_ar[G][C][U][A][U][U][A] = 4.800;
+ int21_ar[G][C][U][C][A][U][A] = 4.800;
+ int21_ar[G][C][U][C][C][U][A] = 3.000;
+ int21_ar[G][C][U][C][G][U][A] = 4.800;
+ int21_ar[G][C][U][C][U][U][A] = 2.100;
+ int21_ar[G][C][U][G][A][U][A] = 4.800;
+ int21_ar[G][C][U][G][C][U][A] = 4.800;
+ int21_ar[G][C][U][G][G][U][A] = 4.800;
+ int21_ar[G][C][U][G][U][U][A] = 4.800;
+ int21_ar[G][C][U][U][A][U][A] = 4.800;
+ int21_ar[G][C][U][U][C][U][A] = 2.500;
+ int21_ar[G][C][U][U][G][U][A] = 4.800;
+ int21_ar[G][C][U][U][U][U][A] = 2.000;
+ int21_ar[G][C][A][A][A][U][G] = 3.200;
+ int21_ar[G][C][A][A][C][U][G] = 3.000;
+ int21_ar[G][C][A][A][G][U][G] = 2.400;
+ int21_ar[G][C][A][A][U][U][G] = 4.800;
+ int21_ar[G][C][A][C][A][U][G] = 2.900;
+ int21_ar[G][C][A][C][C][U][G] = 2.500;
+ int21_ar[G][C][A][C][G][U][G] = 2.400;
+ int21_ar[G][C][A][C][U][U][G] = 4.800;
+ int21_ar[G][C][A][G][A][U][G] = 1.800;
+ int21_ar[G][C][A][G][C][U][G] = 1.400;
+ int21_ar[G][C][A][G][G][U][G] = 1.200;
+ int21_ar[G][C][A][G][U][U][G] = 4.800;
+ int21_ar[G][C][A][U][A][U][G] = 4.800;
+ int21_ar[G][C][A][U][C][U][G] = 4.800;
+ int21_ar[G][C][A][U][G][U][G] = 4.800;
+ int21_ar[G][C][A][U][U][U][G] = 4.800;
+ int21_ar[G][C][C][A][A][U][G] = 3.100;
+ int21_ar[G][C][C][A][C][U][G] = 3.000;
+ int21_ar[G][C][C][A][G][U][G] = 4.800;
+ int21_ar[G][C][C][A][U][U][G] = 3.000;
+ int21_ar[G][C][C][C][A][U][G] = 3.000;
+ int21_ar[G][C][C][C][C][U][G] = 3.300;
+ int21_ar[G][C][C][C][G][U][G] = 4.800;
+ int21_ar[G][C][C][C][U][U][G] = 3.000;
+ int21_ar[G][C][C][G][A][U][G] = 4.800;
+ int21_ar[G][C][C][G][C][U][G] = 4.800;
+ int21_ar[G][C][C][G][G][U][G] = 4.800;
+ int21_ar[G][C][C][G][U][U][G] = 4.800;
+ int21_ar[G][C][C][U][A][U][G] = 3.300;
+ int21_ar[G][C][C][U][C][U][G] = 2.700;
+ int21_ar[G][C][C][U][G][U][G] = 4.800;
+ int21_ar[G][C][C][U][U][U][G] = 3.000;
+ int21_ar[G][C][G][A][A][U][G] = 2.500;
+ int21_ar[G][C][G][A][C][U][G] = 4.800;
+ int21_ar[G][C][G][A][G][U][G] = 1.600;
+ int21_ar[G][C][G][A][U][U][G] = 4.800;
+ int21_ar[G][C][G][C][A][U][G] = 4.800;
+ int21_ar[G][C][G][C][C][U][G] = 4.800;
+ int21_ar[G][C][G][C][G][U][G] = 4.800;
+ int21_ar[G][C][G][C][U][U][G] = 4.800;
+ int21_ar[G][C][G][G][A][U][G] = 1.600;
+ int21_ar[G][C][G][G][C][U][G] = 4.800;
+ int21_ar[G][C][G][G][G][U][G] = 3.000;
+ int21_ar[G][C][G][G][U][U][G] = 4.800;
+ int21_ar[G][C][G][U][A][U][G] = 4.800;
+ int21_ar[G][C][G][U][C][U][G] = 4.800;
+ int21_ar[G][C][G][U][G][U][G] = 4.800;
+ int21_ar[G][C][G][U][U][U][G] = 4.800;
+ int21_ar[G][C][U][A][A][U][G] = 4.800;
+ int21_ar[G][C][U][A][C][U][G] = 4.800;
+ int21_ar[G][C][U][A][G][U][G] = 4.800;
+ int21_ar[G][C][U][A][U][U][G] = 4.800;
+ int21_ar[G][C][U][C][A][U][G] = 4.800;
+ int21_ar[G][C][U][C][C][U][G] = 3.000;
+ int21_ar[G][C][U][C][G][U][G] = 4.800;
+ int21_ar[G][C][U][C][U][U][G] = 2.100;
+ int21_ar[G][C][U][G][A][U][G] = 4.800;
+ int21_ar[G][C][U][G][C][U][G] = 4.800;
+ int21_ar[G][C][U][G][G][U][G] = 4.800;
+ int21_ar[G][C][U][G][U][U][G] = 4.800;
+ int21_ar[G][C][U][U][A][U][G] = 4.800;
+ int21_ar[G][C][U][U][C][U][G] = 2.500;
+ int21_ar[G][C][U][U][G][U][G] = 4.800;
+ int21_ar[G][C][U][U][U][U][G] = 2.000;
+ int21_ar[G][U][A][A][A][A][U] = 3.900;
+ int21_ar[G][U][A][A][C][A][U] = 3.700;
+ int21_ar[G][U][A][A][G][A][U] = 3.100;
+ int21_ar[G][U][A][A][U][A][U] = 5.500;
+ int21_ar[G][U][A][C][A][A][U] = 3.600;
+ int21_ar[G][U][A][C][C][A][U] = 3.200;
+ int21_ar[G][U][A][C][G][A][U] = 3.100;
+ int21_ar[G][U][A][C][U][A][U] = 5.500;
+ int21_ar[G][U][A][G][A][A][U] = 2.500;
+ int21_ar[G][U][A][G][C][A][U] = 2.100;
+ int21_ar[G][U][A][G][G][A][U] = 1.900;
+ int21_ar[G][U][A][G][U][A][U] = 5.500;
+ int21_ar[G][U][A][U][A][A][U] = 5.500;
+ int21_ar[G][U][A][U][C][A][U] = 5.500;
+ int21_ar[G][U][A][U][G][A][U] = 5.500;
+ int21_ar[G][U][A][U][U][A][U] = 5.500;
+ int21_ar[G][U][C][A][A][A][U] = 3.800;
+ int21_ar[G][U][C][A][C][A][U] = 3.700;
+ int21_ar[G][U][C][A][G][A][U] = 5.500;
+ int21_ar[G][U][C][A][U][A][U] = 3.700;
+ int21_ar[G][U][C][C][A][A][U] = 3.700;
+ int21_ar[G][U][C][C][C][A][U] = 4.000;
+ int21_ar[G][U][C][C][G][A][U] = 5.500;
+ int21_ar[G][U][C][C][U][A][U] = 3.700;
+ int21_ar[G][U][C][G][A][A][U] = 5.500;
+ int21_ar[G][U][C][G][C][A][U] = 5.500;
+ int21_ar[G][U][C][G][G][A][U] = 5.500;
+ int21_ar[G][U][C][G][U][A][U] = 5.500;
+ int21_ar[G][U][C][U][A][A][U] = 4.000;
+ int21_ar[G][U][C][U][C][A][U] = 3.400;
+ int21_ar[G][U][C][U][G][A][U] = 5.500;
+ int21_ar[G][U][C][U][U][A][U] = 3.700;
+ int21_ar[G][U][G][A][A][A][U] = 3.200;
+ int21_ar[G][U][G][A][C][A][U] = 5.500;
+ int21_ar[G][U][G][A][G][A][U] = 2.300;
+ int21_ar[G][U][G][A][U][A][U] = 5.500;
+ int21_ar[G][U][G][C][A][A][U] = 5.500;
+ int21_ar[G][U][G][C][C][A][U] = 5.500;
+ int21_ar[G][U][G][C][G][A][U] = 5.500;
+ int21_ar[G][U][G][C][U][A][U] = 5.500;
+ int21_ar[G][U][G][G][A][A][U] = 2.300;
+ int21_ar[G][U][G][G][C][A][U] = 5.500;
+ int21_ar[G][U][G][G][G][A][U] = 3.700;
+ int21_ar[G][U][G][G][U][A][U] = 5.500;
+ int21_ar[G][U][G][U][A][A][U] = 5.500;
+ int21_ar[G][U][G][U][C][A][U] = 5.500;
+ int21_ar[G][U][G][U][G][A][U] = 5.500;
+ int21_ar[G][U][G][U][U][A][U] = 5.500;
+ int21_ar[G][U][U][A][A][A][U] = 5.500;
+ int21_ar[G][U][U][A][C][A][U] = 5.500;
+ int21_ar[G][U][U][A][G][A][U] = 5.500;
+ int21_ar[G][U][U][A][U][A][U] = 5.500;
+ int21_ar[G][U][U][C][A][A][U] = 5.500;
+ int21_ar[G][U][U][C][C][A][U] = 3.700;
+ int21_ar[G][U][U][C][G][A][U] = 5.500;
+ int21_ar[G][U][U][C][U][A][U] = 2.800;
+ int21_ar[G][U][U][G][A][A][U] = 5.500;
+ int21_ar[G][U][U][G][C][A][U] = 5.500;
+ int21_ar[G][U][U][G][G][A][U] = 5.500;
+ int21_ar[G][U][U][G][U][A][U] = 5.500;
+ int21_ar[G][U][U][U][A][A][U] = 5.500;
+ int21_ar[G][U][U][U][C][A][U] = 3.200;
+ int21_ar[G][U][U][U][G][A][U] = 5.500;
+ int21_ar[G][U][U][U][U][A][U] = 2.700;
+ int21_ar[G][U][A][A][A][C][G] = 3.200;
+ int21_ar[G][U][A][A][C][C][G] = 3.000;
+ int21_ar[G][U][A][A][G][C][G] = 2.400;
+ int21_ar[G][U][A][A][U][C][G] = 4.800;
+ int21_ar[G][U][A][C][A][C][G] = 2.900;
+ int21_ar[G][U][A][C][C][C][G] = 2.500;
+ int21_ar[G][U][A][C][G][C][G] = 2.400;
+ int21_ar[G][U][A][C][U][C][G] = 4.800;
+ int21_ar[G][U][A][G][A][C][G] = 1.800;
+ int21_ar[G][U][A][G][C][C][G] = 1.400;
+ int21_ar[G][U][A][G][G][C][G] = 1.200;
+ int21_ar[G][U][A][G][U][C][G] = 4.800;
+ int21_ar[G][U][A][U][A][C][G] = 4.800;
+ int21_ar[G][U][A][U][C][C][G] = 4.800;
+ int21_ar[G][U][A][U][G][C][G] = 4.800;
+ int21_ar[G][U][A][U][U][C][G] = 4.800;
+ int21_ar[G][U][C][A][A][C][G] = 3.100;
+ int21_ar[G][U][C][A][C][C][G] = 3.000;
+ int21_ar[G][U][C][A][G][C][G] = 4.800;
+ int21_ar[G][U][C][A][U][C][G] = 3.000;
+ int21_ar[G][U][C][C][A][C][G] = 3.000;
+ int21_ar[G][U][C][C][C][C][G] = 3.300;
+ int21_ar[G][U][C][C][G][C][G] = 4.800;
+ int21_ar[G][U][C][C][U][C][G] = 3.000;
+ int21_ar[G][U][C][G][A][C][G] = 4.800;
+ int21_ar[G][U][C][G][C][C][G] = 4.800;
+ int21_ar[G][U][C][G][G][C][G] = 4.800;
+ int21_ar[G][U][C][G][U][C][G] = 4.800;
+ int21_ar[G][U][C][U][A][C][G] = 3.300;
+ int21_ar[G][U][C][U][C][C][G] = 2.700;
+ int21_ar[G][U][C][U][G][C][G] = 4.800;
+ int21_ar[G][U][C][U][U][C][G] = 3.000;
+ int21_ar[G][U][G][A][A][C][G] = 2.500;
+ int21_ar[G][U][G][A][C][C][G] = 4.800;
+ int21_ar[G][U][G][A][G][C][G] = 1.600;
+ int21_ar[G][U][G][A][U][C][G] = 4.800;
+ int21_ar[G][U][G][C][A][C][G] = 4.800;
+ int21_ar[G][U][G][C][C][C][G] = 4.800;
+ int21_ar[G][U][G][C][G][C][G] = 4.800;
+ int21_ar[G][U][G][C][U][C][G] = 4.800;
+ int21_ar[G][U][G][G][A][C][G] = 1.600;
+ int21_ar[G][U][G][G][C][C][G] = 4.800;
+ int21_ar[G][U][G][G][G][C][G] = 3.000;
+ int21_ar[G][U][G][G][U][C][G] = 4.800;
+ int21_ar[G][U][G][U][A][C][G] = 4.800;
+ int21_ar[G][U][G][U][C][C][G] = 4.800;
+ int21_ar[G][U][G][U][G][C][G] = 4.800;
+ int21_ar[G][U][G][U][U][C][G] = 4.800;
+ int21_ar[G][U][U][A][A][C][G] = 4.800;
+ int21_ar[G][U][U][A][C][C][G] = 4.800;
+ int21_ar[G][U][U][A][G][C][G] = 4.800;
+ int21_ar[G][U][U][A][U][C][G] = 4.800;
+ int21_ar[G][U][U][C][A][C][G] = 4.800;
+ int21_ar[G][U][U][C][C][C][G] = 3.000;
+ int21_ar[G][U][U][C][G][C][G] = 4.800;
+ int21_ar[G][U][U][C][U][C][G] = 2.100;
+ int21_ar[G][U][U][G][A][C][G] = 4.800;
+ int21_ar[G][U][U][G][C][C][G] = 4.800;
+ int21_ar[G][U][U][G][G][C][G] = 4.800;
+ int21_ar[G][U][U][G][U][C][G] = 4.800;
+ int21_ar[G][U][U][U][A][C][G] = 4.800;
+ int21_ar[G][U][U][U][C][C][G] = 2.500;
+ int21_ar[G][U][U][U][G][C][G] = 4.800;
+ int21_ar[G][U][U][U][U][C][G] = 2.000;
+ int21_ar[G][U][A][A][A][G][C] = 3.200;
+ int21_ar[G][U][A][A][C][G][C] = 3.000;
+ int21_ar[G][U][A][A][G][G][C] = 2.400;
+ int21_ar[G][U][A][A][U][G][C] = 4.800;
+ int21_ar[G][U][A][C][A][G][C] = 2.900;
+ int21_ar[G][U][A][C][C][G][C] = 2.500;
+ int21_ar[G][U][A][C][G][G][C] = 2.400;
+ int21_ar[G][U][A][C][U][G][C] = 4.800;
+ int21_ar[G][U][A][G][A][G][C] = 1.800;
+ int21_ar[G][U][A][G][C][G][C] = 1.400;
+ int21_ar[G][U][A][G][G][G][C] = 1.200;
+ int21_ar[G][U][A][G][U][G][C] = 4.800;
+ int21_ar[G][U][A][U][A][G][C] = 4.800;
+ int21_ar[G][U][A][U][C][G][C] = 4.800;
+ int21_ar[G][U][A][U][G][G][C] = 4.800;
+ int21_ar[G][U][A][U][U][G][C] = 4.800;
+ int21_ar[G][U][C][A][A][G][C] = 3.100;
+ int21_ar[G][U][C][A][C][G][C] = 3.000;
+ int21_ar[G][U][C][A][G][G][C] = 4.800;
+ int21_ar[G][U][C][A][U][G][C] = 3.000;
+ int21_ar[G][U][C][C][A][G][C] = 3.000;
+ int21_ar[G][U][C][C][C][G][C] = 3.300;
+ int21_ar[G][U][C][C][G][G][C] = 4.800;
+ int21_ar[G][U][C][C][U][G][C] = 3.000;
+ int21_ar[G][U][C][G][A][G][C] = 4.800;
+ int21_ar[G][U][C][G][C][G][C] = 4.800;
+ int21_ar[G][U][C][G][G][G][C] = 4.800;
+ int21_ar[G][U][C][G][U][G][C] = 4.800;
+ int21_ar[G][U][C][U][A][G][C] = 3.300;
+ int21_ar[G][U][C][U][C][G][C] = 2.700;
+ int21_ar[G][U][C][U][G][G][C] = 4.800;
+ int21_ar[G][U][C][U][U][G][C] = 3.000;
+ int21_ar[G][U][G][A][A][G][C] = 2.500;
+ int21_ar[G][U][G][A][C][G][C] = 4.800;
+ int21_ar[G][U][G][A][G][G][C] = 1.600;
+ int21_ar[G][U][G][A][U][G][C] = 4.800;
+ int21_ar[G][U][G][C][A][G][C] = 4.800;
+ int21_ar[G][U][G][C][C][G][C] = 4.800;
+ int21_ar[G][U][G][C][G][G][C] = 4.800;
+ int21_ar[G][U][G][C][U][G][C] = 4.800;
+ int21_ar[G][U][G][G][A][G][C] = 1.600;
+ int21_ar[G][U][G][G][C][G][C] = 4.800;
+ int21_ar[G][U][G][G][G][G][C] = 3.000;
+ int21_ar[G][U][G][G][U][G][C] = 4.800;
+ int21_ar[G][U][G][U][A][G][C] = 4.800;
+ int21_ar[G][U][G][U][C][G][C] = 4.800;
+ int21_ar[G][U][G][U][G][G][C] = 4.800;
+ int21_ar[G][U][G][U][U][G][C] = 4.800;
+ int21_ar[G][U][U][A][A][G][C] = 4.800;
+ int21_ar[G][U][U][A][C][G][C] = 4.800;
+ int21_ar[G][U][U][A][G][G][C] = 4.800;
+ int21_ar[G][U][U][A][U][G][C] = 4.800;
+ int21_ar[G][U][U][C][A][G][C] = 4.800;
+ int21_ar[G][U][U][C][C][G][C] = 3.000;
+ int21_ar[G][U][U][C][G][G][C] = 4.800;
+ int21_ar[G][U][U][C][U][G][C] = 2.100;
+ int21_ar[G][U][U][G][A][G][C] = 4.800;
+ int21_ar[G][U][U][G][C][G][C] = 4.800;
+ int21_ar[G][U][U][G][G][G][C] = 4.800;
+ int21_ar[G][U][U][G][U][G][C] = 4.800;
+ int21_ar[G][U][U][U][A][G][C] = 4.800;
+ int21_ar[G][U][U][U][C][G][C] = 2.500;
+ int21_ar[G][U][U][U][G][G][C] = 4.800;
+ int21_ar[G][U][U][U][U][G][C] = 2.000;
+ int21_ar[G][U][A][A][A][G][U] = 3.900;
+ int21_ar[G][U][A][A][C][G][U] = 3.700;
+ int21_ar[G][U][A][A][G][G][U] = 3.100;
+ int21_ar[G][U][A][A][U][G][U] = 5.500;
+ int21_ar[G][U][A][C][A][G][U] = 3.600;
+ int21_ar[G][U][A][C][C][G][U] = 3.200;
+ int21_ar[G][U][A][C][G][G][U] = 3.100;
+ int21_ar[G][U][A][C][U][G][U] = 5.500;
+ int21_ar[G][U][A][G][A][G][U] = 2.500;
+ int21_ar[G][U][A][G][C][G][U] = 2.100;
+ int21_ar[G][U][A][G][G][G][U] = 1.900;
+ int21_ar[G][U][A][G][U][G][U] = 5.500;
+ int21_ar[G][U][A][U][A][G][U] = 5.500;
+ int21_ar[G][U][A][U][C][G][U] = 5.500;
+ int21_ar[G][U][A][U][G][G][U] = 5.500;
+ int21_ar[G][U][A][U][U][G][U] = 5.500;
+ int21_ar[G][U][C][A][A][G][U] = 3.800;
+ int21_ar[G][U][C][A][C][G][U] = 3.700;
+ int21_ar[G][U][C][A][G][G][U] = 5.500;
+ int21_ar[G][U][C][A][U][G][U] = 3.700;
+ int21_ar[G][U][C][C][A][G][U] = 3.700;
+ int21_ar[G][U][C][C][C][G][U] = 4.000;
+ int21_ar[G][U][C][C][G][G][U] = 5.500;
+ int21_ar[G][U][C][C][U][G][U] = 3.700;
+ int21_ar[G][U][C][G][A][G][U] = 5.500;
+ int21_ar[G][U][C][G][C][G][U] = 5.500;
+ int21_ar[G][U][C][G][G][G][U] = 5.500;
+ int21_ar[G][U][C][G][U][G][U] = 5.500;
+ int21_ar[G][U][C][U][A][G][U] = 4.000;
+ int21_ar[G][U][C][U][C][G][U] = 3.400;
+ int21_ar[G][U][C][U][G][G][U] = 5.500;
+ int21_ar[G][U][C][U][U][G][U] = 3.700;
+ int21_ar[G][U][G][A][A][G][U] = 3.200;
+ int21_ar[G][U][G][A][C][G][U] = 5.500;
+ int21_ar[G][U][G][A][G][G][U] = 2.300;
+ int21_ar[G][U][G][A][U][G][U] = 5.500;
+ int21_ar[G][U][G][C][A][G][U] = 5.500;
+ int21_ar[G][U][G][C][C][G][U] = 5.500;
+ int21_ar[G][U][G][C][G][G][U] = 5.500;
+ int21_ar[G][U][G][C][U][G][U] = 5.500;
+ int21_ar[G][U][G][G][A][G][U] = 2.300;
+ int21_ar[G][U][G][G][C][G][U] = 5.500;
+ int21_ar[G][U][G][G][G][G][U] = 3.700;
+ int21_ar[G][U][G][G][U][G][U] = 5.500;
+ int21_ar[G][U][G][U][A][G][U] = 5.500;
+ int21_ar[G][U][G][U][C][G][U] = 5.500;
+ int21_ar[G][U][G][U][G][G][U] = 5.500;
+ int21_ar[G][U][G][U][U][G][U] = 5.500;
+ int21_ar[G][U][U][A][A][G][U] = 5.500;
+ int21_ar[G][U][U][A][C][G][U] = 5.500;
+ int21_ar[G][U][U][A][G][G][U] = 5.500;
+ int21_ar[G][U][U][A][U][G][U] = 5.500;
+ int21_ar[G][U][U][C][A][G][U] = 5.500;
+ int21_ar[G][U][U][C][C][G][U] = 3.700;
+ int21_ar[G][U][U][C][G][G][U] = 5.500;
+ int21_ar[G][U][U][C][U][G][U] = 2.800;
+ int21_ar[G][U][U][G][A][G][U] = 5.500;
+ int21_ar[G][U][U][G][C][G][U] = 5.500;
+ int21_ar[G][U][U][G][G][G][U] = 5.500;
+ int21_ar[G][U][U][G][U][G][U] = 5.500;
+ int21_ar[G][U][U][U][A][G][U] = 5.500;
+ int21_ar[G][U][U][U][C][G][U] = 3.200;
+ int21_ar[G][U][U][U][G][G][U] = 5.500;
+ int21_ar[G][U][U][U][U][G][U] = 2.700;
+ int21_ar[G][U][A][A][A][U][A] = 3.900;
+ int21_ar[G][U][A][A][C][U][A] = 3.700;
+ int21_ar[G][U][A][A][G][U][A] = 3.100;
+ int21_ar[G][U][A][A][U][U][A] = 5.500;
+ int21_ar[G][U][A][C][A][U][A] = 3.600;
+ int21_ar[G][U][A][C][C][U][A] = 3.200;
+ int21_ar[G][U][A][C][G][U][A] = 3.100;
+ int21_ar[G][U][A][C][U][U][A] = 5.500;
+ int21_ar[G][U][A][G][A][U][A] = 2.500;
+ int21_ar[G][U][A][G][C][U][A] = 2.100;
+ int21_ar[G][U][A][G][G][U][A] = 1.900;
+ int21_ar[G][U][A][G][U][U][A] = 5.500;
+ int21_ar[G][U][A][U][A][U][A] = 5.500;
+ int21_ar[G][U][A][U][C][U][A] = 5.500;
+ int21_ar[G][U][A][U][G][U][A] = 5.500;
+ int21_ar[G][U][A][U][U][U][A] = 5.500;
+ int21_ar[G][U][C][A][A][U][A] = 3.800;
+ int21_ar[G][U][C][A][C][U][A] = 3.700;
+ int21_ar[G][U][C][A][G][U][A] = 5.500;
+ int21_ar[G][U][C][A][U][U][A] = 3.700;
+ int21_ar[G][U][C][C][A][U][A] = 3.700;
+ int21_ar[G][U][C][C][C][U][A] = 4.000;
+ int21_ar[G][U][C][C][G][U][A] = 5.500;
+ int21_ar[G][U][C][C][U][U][A] = 3.700;
+ int21_ar[G][U][C][G][A][U][A] = 5.500;
+ int21_ar[G][U][C][G][C][U][A] = 5.500;
+ int21_ar[G][U][C][G][G][U][A] = 5.500;
+ int21_ar[G][U][C][G][U][U][A] = 5.500;
+ int21_ar[G][U][C][U][A][U][A] = 4.000;
+ int21_ar[G][U][C][U][C][U][A] = 3.400;
+ int21_ar[G][U][C][U][G][U][A] = 5.500;
+ int21_ar[G][U][C][U][U][U][A] = 3.700;
+ int21_ar[G][U][G][A][A][U][A] = 3.200;
+ int21_ar[G][U][G][A][C][U][A] = 5.500;
+ int21_ar[G][U][G][A][G][U][A] = 2.300;
+ int21_ar[G][U][G][A][U][U][A] = 5.500;
+ int21_ar[G][U][G][C][A][U][A] = 5.500;
+ int21_ar[G][U][G][C][C][U][A] = 5.500;
+ int21_ar[G][U][G][C][G][U][A] = 5.500;
+ int21_ar[G][U][G][C][U][U][A] = 5.500;
+ int21_ar[G][U][G][G][A][U][A] = 2.300;
+ int21_ar[G][U][G][G][C][U][A] = 5.500;
+ int21_ar[G][U][G][G][G][U][A] = 3.700;
+ int21_ar[G][U][G][G][U][U][A] = 5.500;
+ int21_ar[G][U][G][U][A][U][A] = 5.500;
+ int21_ar[G][U][G][U][C][U][A] = 5.500;
+ int21_ar[G][U][G][U][G][U][A] = 5.500;
+ int21_ar[G][U][G][U][U][U][A] = 5.500;
+ int21_ar[G][U][U][A][A][U][A] = 5.500;
+ int21_ar[G][U][U][A][C][U][A] = 5.500;
+ int21_ar[G][U][U][A][G][U][A] = 5.500;
+ int21_ar[G][U][U][A][U][U][A] = 5.500;
+ int21_ar[G][U][U][C][A][U][A] = 5.500;
+ int21_ar[G][U][U][C][C][U][A] = 3.700;
+ int21_ar[G][U][U][C][G][U][A] = 5.500;
+ int21_ar[G][U][U][C][U][U][A] = 2.800;
+ int21_ar[G][U][U][G][A][U][A] = 5.500;
+ int21_ar[G][U][U][G][C][U][A] = 5.500;
+ int21_ar[G][U][U][G][G][U][A] = 5.500;
+ int21_ar[G][U][U][G][U][U][A] = 5.500;
+ int21_ar[G][U][U][U][A][U][A] = 5.500;
+ int21_ar[G][U][U][U][C][U][A] = 3.200;
+ int21_ar[G][U][U][U][G][U][A] = 5.500;
+ int21_ar[G][U][U][U][U][U][A] = 2.700;
+ int21_ar[G][U][A][A][A][U][G] = 3.900;
+ int21_ar[G][U][A][A][C][U][G] = 3.700;
+ int21_ar[G][U][A][A][G][U][G] = 3.100;
+ int21_ar[G][U][A][A][U][U][G] = 5.500;
+ int21_ar[G][U][A][C][A][U][G] = 3.600;
+ int21_ar[G][U][A][C][C][U][G] = 3.200;
+ int21_ar[G][U][A][C][G][U][G] = 3.100;
+ int21_ar[G][U][A][C][U][U][G] = 5.500;
+ int21_ar[G][U][A][G][A][U][G] = 2.500;
+ int21_ar[G][U][A][G][C][U][G] = 2.100;
+ int21_ar[G][U][A][G][G][U][G] = 1.900;
+ int21_ar[G][U][A][G][U][U][G] = 5.500;
+ int21_ar[G][U][A][U][A][U][G] = 5.500;
+ int21_ar[G][U][A][U][C][U][G] = 5.500;
+ int21_ar[G][U][A][U][G][U][G] = 5.500;
+ int21_ar[G][U][A][U][U][U][G] = 5.500;
+ int21_ar[G][U][C][A][A][U][G] = 3.800;
+ int21_ar[G][U][C][A][C][U][G] = 3.700;
+ int21_ar[G][U][C][A][G][U][G] = 5.500;
+ int21_ar[G][U][C][A][U][U][G] = 3.700;
+ int21_ar[G][U][C][C][A][U][G] = 3.700;
+ int21_ar[G][U][C][C][C][U][G] = 4.000;
+ int21_ar[G][U][C][C][G][U][G] = 5.500;
+ int21_ar[G][U][C][C][U][U][G] = 3.700;
+ int21_ar[G][U][C][G][A][U][G] = 5.500;
+ int21_ar[G][U][C][G][C][U][G] = 5.500;
+ int21_ar[G][U][C][G][G][U][G] = 5.500;
+ int21_ar[G][U][C][G][U][U][G] = 5.500;
+ int21_ar[G][U][C][U][A][U][G] = 4.000;
+ int21_ar[G][U][C][U][C][U][G] = 3.400;
+ int21_ar[G][U][C][U][G][U][G] = 5.500;
+ int21_ar[G][U][C][U][U][U][G] = 3.700;
+ int21_ar[G][U][G][A][A][U][G] = 3.200;
+ int21_ar[G][U][G][A][C][U][G] = 5.500;
+ int21_ar[G][U][G][A][G][U][G] = 2.300;
+ int21_ar[G][U][G][A][U][U][G] = 5.500;
+ int21_ar[G][U][G][C][A][U][G] = 5.500;
+ int21_ar[G][U][G][C][C][U][G] = 5.500;
+ int21_ar[G][U][G][C][G][U][G] = 5.500;
+ int21_ar[G][U][G][C][U][U][G] = 5.500;
+ int21_ar[G][U][G][G][A][U][G] = 2.300;
+ int21_ar[G][U][G][G][C][U][G] = 5.500;
+ int21_ar[G][U][G][G][G][U][G] = 3.700;
+ int21_ar[G][U][G][G][U][U][G] = 5.500;
+ int21_ar[G][U][G][U][A][U][G] = 5.500;
+ int21_ar[G][U][G][U][C][U][G] = 5.500;
+ int21_ar[G][U][G][U][G][U][G] = 5.500;
+ int21_ar[G][U][G][U][U][U][G] = 5.500;
+ int21_ar[G][U][U][A][A][U][G] = 5.500;
+ int21_ar[G][U][U][A][C][U][G] = 5.500;
+ int21_ar[G][U][U][A][G][U][G] = 5.500;
+ int21_ar[G][U][U][A][U][U][G] = 5.500;
+ int21_ar[G][U][U][C][A][U][G] = 5.500;
+ int21_ar[G][U][U][C][C][U][G] = 3.700;
+ int21_ar[G][U][U][C][G][U][G] = 5.500;
+ int21_ar[G][U][U][C][U][U][G] = 2.800;
+ int21_ar[G][U][U][G][A][U][G] = 5.500;
+ int21_ar[G][U][U][G][C][U][G] = 5.500;
+ int21_ar[G][U][U][G][G][U][G] = 5.500;
+ int21_ar[G][U][U][G][U][U][G] = 5.500;
+ int21_ar[G][U][U][U][A][U][G] = 5.500;
+ int21_ar[G][U][U][U][C][U][G] = 3.200;
+ int21_ar[G][U][U][U][G][U][G] = 5.500;
+ int21_ar[G][U][U][U][U][U][G] = 2.700;
+ int21_ar[U][A][A][A][A][A][U] = 3.900;
+ int21_ar[U][A][A][A][C][A][U] = 3.700;
+ int21_ar[U][A][A][A][G][A][U] = 3.100;
+ int21_ar[U][A][A][A][U][A][U] = 5.500;
+ int21_ar[U][A][A][C][A][A][U] = 3.600;
+ int21_ar[U][A][A][C][C][A][U] = 3.200;
+ int21_ar[U][A][A][C][G][A][U] = 3.100;
+ int21_ar[U][A][A][C][U][A][U] = 5.500;
+ int21_ar[U][A][A][G][A][A][U] = 2.500;
+ int21_ar[U][A][A][G][C][A][U] = 2.100;
+ int21_ar[U][A][A][G][G][A][U] = 1.900;
+ int21_ar[U][A][A][G][U][A][U] = 5.500;
+ int21_ar[U][A][A][U][A][A][U] = 5.500;
+ int21_ar[U][A][A][U][C][A][U] = 5.500;
+ int21_ar[U][A][A][U][G][A][U] = 5.500;
+ int21_ar[U][A][A][U][U][A][U] = 5.500;
+ int21_ar[U][A][C][A][A][A][U] = 3.800;
+ int21_ar[U][A][C][A][C][A][U] = 3.700;
+ int21_ar[U][A][C][A][G][A][U] = 5.500;
+ int21_ar[U][A][C][A][U][A][U] = 3.700;
+ int21_ar[U][A][C][C][A][A][U] = 3.700;
+ int21_ar[U][A][C][C][C][A][U] = 4.000;
+ int21_ar[U][A][C][C][G][A][U] = 5.500;
+ int21_ar[U][A][C][C][U][A][U] = 3.700;
+ int21_ar[U][A][C][G][A][A][U] = 5.500;
+ int21_ar[U][A][C][G][C][A][U] = 5.500;
+ int21_ar[U][A][C][G][G][A][U] = 5.500;
+ int21_ar[U][A][C][G][U][A][U] = 5.500;
+ int21_ar[U][A][C][U][A][A][U] = 4.000;
+ int21_ar[U][A][C][U][C][A][U] = 3.400;
+ int21_ar[U][A][C][U][G][A][U] = 5.500;
+ int21_ar[U][A][C][U][U][A][U] = 3.700;
+ int21_ar[U][A][G][A][A][A][U] = 3.200;
+ int21_ar[U][A][G][A][C][A][U] = 5.500;
+ int21_ar[U][A][G][A][G][A][U] = 2.300;
+ int21_ar[U][A][G][A][U][A][U] = 5.500;
+ int21_ar[U][A][G][C][A][A][U] = 5.500;
+ int21_ar[U][A][G][C][C][A][U] = 5.500;
+ int21_ar[U][A][G][C][G][A][U] = 5.500;
+ int21_ar[U][A][G][C][U][A][U] = 5.500;
+ int21_ar[U][A][G][G][A][A][U] = 2.300;
+ int21_ar[U][A][G][G][C][A][U] = 5.500;
+ int21_ar[U][A][G][G][G][A][U] = 3.700;
+ int21_ar[U][A][G][G][U][A][U] = 5.500;
+ int21_ar[U][A][G][U][A][A][U] = 5.500;
+ int21_ar[U][A][G][U][C][A][U] = 5.500;
+ int21_ar[U][A][G][U][G][A][U] = 5.500;
+ int21_ar[U][A][G][U][U][A][U] = 5.500;
+ int21_ar[U][A][U][A][A][A][U] = 5.500;
+ int21_ar[U][A][U][A][C][A][U] = 5.500;
+ int21_ar[U][A][U][A][G][A][U] = 5.500;
+ int21_ar[U][A][U][A][U][A][U] = 5.500;
+ int21_ar[U][A][U][C][A][A][U] = 5.500;
+ int21_ar[U][A][U][C][C][A][U] = 3.700;
+ int21_ar[U][A][U][C][G][A][U] = 5.500;
+ int21_ar[U][A][U][C][U][A][U] = 2.800;
+ int21_ar[U][A][U][G][A][A][U] = 5.500;
+ int21_ar[U][A][U][G][C][A][U] = 5.500;
+ int21_ar[U][A][U][G][G][A][U] = 5.500;
+ int21_ar[U][A][U][G][U][A][U] = 5.500;
+ int21_ar[U][A][U][U][A][A][U] = 5.500;
+ int21_ar[U][A][U][U][C][A][U] = 3.200;
+ int21_ar[U][A][U][U][G][A][U] = 5.500;
+ int21_ar[U][A][U][U][U][A][U] = 2.700;
+ int21_ar[U][A][A][A][A][C][G] = 3.200;
+ int21_ar[U][A][A][A][C][C][G] = 3.000;
+ int21_ar[U][A][A][A][G][C][G] = 2.400;
+ int21_ar[U][A][A][A][U][C][G] = 4.800;
+ int21_ar[U][A][A][C][A][C][G] = 2.900;
+ int21_ar[U][A][A][C][C][C][G] = 2.500;
+ int21_ar[U][A][A][C][G][C][G] = 2.400;
+ int21_ar[U][A][A][C][U][C][G] = 4.800;
+ int21_ar[U][A][A][G][A][C][G] = 1.800;
+ int21_ar[U][A][A][G][C][C][G] = 1.400;
+ int21_ar[U][A][A][G][G][C][G] = 1.200;
+ int21_ar[U][A][A][G][U][C][G] = 4.800;
+ int21_ar[U][A][A][U][A][C][G] = 4.800;
+ int21_ar[U][A][A][U][C][C][G] = 4.800;
+ int21_ar[U][A][A][U][G][C][G] = 4.800;
+ int21_ar[U][A][A][U][U][C][G] = 4.800;
+ int21_ar[U][A][C][A][A][C][G] = 3.100;
+ int21_ar[U][A][C][A][C][C][G] = 3.000;
+ int21_ar[U][A][C][A][G][C][G] = 4.800;
+ int21_ar[U][A][C][A][U][C][G] = 3.000;
+ int21_ar[U][A][C][C][A][C][G] = 3.000;
+ int21_ar[U][A][C][C][C][C][G] = 3.300;
+ int21_ar[U][A][C][C][G][C][G] = 4.800;
+ int21_ar[U][A][C][C][U][C][G] = 3.000;
+ int21_ar[U][A][C][G][A][C][G] = 4.800;
+ int21_ar[U][A][C][G][C][C][G] = 4.800;
+ int21_ar[U][A][C][G][G][C][G] = 4.800;
+ int21_ar[U][A][C][G][U][C][G] = 4.800;
+ int21_ar[U][A][C][U][A][C][G] = 3.300;
+ int21_ar[U][A][C][U][C][C][G] = 2.700;
+ int21_ar[U][A][C][U][G][C][G] = 4.800;
+ int21_ar[U][A][C][U][U][C][G] = 3.000;
+ int21_ar[U][A][G][A][A][C][G] = 2.500;
+ int21_ar[U][A][G][A][C][C][G] = 4.800;
+ int21_ar[U][A][G][A][G][C][G] = 1.600;
+ int21_ar[U][A][G][A][U][C][G] = 4.800;
+ int21_ar[U][A][G][C][A][C][G] = 4.800;
+ int21_ar[U][A][G][C][C][C][G] = 4.800;
+ int21_ar[U][A][G][C][G][C][G] = 4.800;
+ int21_ar[U][A][G][C][U][C][G] = 4.800;
+ int21_ar[U][A][G][G][A][C][G] = 1.600;
+ int21_ar[U][A][G][G][C][C][G] = 4.800;
+ int21_ar[U][A][G][G][G][C][G] = 3.000;
+ int21_ar[U][A][G][G][U][C][G] = 4.800;
+ int21_ar[U][A][G][U][A][C][G] = 4.800;
+ int21_ar[U][A][G][U][C][C][G] = 4.800;
+ int21_ar[U][A][G][U][G][C][G] = 4.800;
+ int21_ar[U][A][G][U][U][C][G] = 4.800;
+ int21_ar[U][A][U][A][A][C][G] = 4.800;
+ int21_ar[U][A][U][A][C][C][G] = 4.800;
+ int21_ar[U][A][U][A][G][C][G] = 4.800;
+ int21_ar[U][A][U][A][U][C][G] = 4.800;
+ int21_ar[U][A][U][C][A][C][G] = 4.800;
+ int21_ar[U][A][U][C][C][C][G] = 3.000;
+ int21_ar[U][A][U][C][G][C][G] = 4.800;
+ int21_ar[U][A][U][C][U][C][G] = 2.100;
+ int21_ar[U][A][U][G][A][C][G] = 4.800;
+ int21_ar[U][A][U][G][C][C][G] = 4.800;
+ int21_ar[U][A][U][G][G][C][G] = 4.800;
+ int21_ar[U][A][U][G][U][C][G] = 4.800;
+ int21_ar[U][A][U][U][A][C][G] = 4.800;
+ int21_ar[U][A][U][U][C][C][G] = 2.500;
+ int21_ar[U][A][U][U][G][C][G] = 4.800;
+ int21_ar[U][A][U][U][U][C][G] = 2.000;
+ int21_ar[U][A][A][A][A][G][C] = 3.200;
+ int21_ar[U][A][A][A][C][G][C] = 3.000;
+ int21_ar[U][A][A][A][G][G][C] = 2.400;
+ int21_ar[U][A][A][A][U][G][C] = 4.800;
+ int21_ar[U][A][A][C][A][G][C] = 2.900;
+ int21_ar[U][A][A][C][C][G][C] = 2.500;
+ int21_ar[U][A][A][C][G][G][C] = 2.400;
+ int21_ar[U][A][A][C][U][G][C] = 4.800;
+ int21_ar[U][A][A][G][A][G][C] = 1.800;
+ int21_ar[U][A][A][G][C][G][C] = 1.400;
+ int21_ar[U][A][A][G][G][G][C] = 1.200;
+ int21_ar[U][A][A][G][U][G][C] = 4.800;
+ int21_ar[U][A][A][U][A][G][C] = 4.800;
+ int21_ar[U][A][A][U][C][G][C] = 4.800;
+ int21_ar[U][A][A][U][G][G][C] = 4.800;
+ int21_ar[U][A][A][U][U][G][C] = 4.800;
+ int21_ar[U][A][C][A][A][G][C] = 3.100;
+ int21_ar[U][A][C][A][C][G][C] = 3.000;
+ int21_ar[U][A][C][A][G][G][C] = 4.800;
+ int21_ar[U][A][C][A][U][G][C] = 3.000;
+ int21_ar[U][A][C][C][A][G][C] = 3.000;
+ int21_ar[U][A][C][C][C][G][C] = 3.300;
+ int21_ar[U][A][C][C][G][G][C] = 4.800;
+ int21_ar[U][A][C][C][U][G][C] = 3.000;
+ int21_ar[U][A][C][G][A][G][C] = 4.800;
+ int21_ar[U][A][C][G][C][G][C] = 4.800;
+ int21_ar[U][A][C][G][G][G][C] = 4.800;
+ int21_ar[U][A][C][G][U][G][C] = 4.800;
+ int21_ar[U][A][C][U][A][G][C] = 3.300;
+ int21_ar[U][A][C][U][C][G][C] = 2.700;
+ int21_ar[U][A][C][U][G][G][C] = 4.800;
+ int21_ar[U][A][C][U][U][G][C] = 3.000;
+ int21_ar[U][A][G][A][A][G][C] = 2.500;
+ int21_ar[U][A][G][A][C][G][C] = 4.800;
+ int21_ar[U][A][G][A][G][G][C] = 1.600;
+ int21_ar[U][A][G][A][U][G][C] = 4.800;
+ int21_ar[U][A][G][C][A][G][C] = 4.800;
+ int21_ar[U][A][G][C][C][G][C] = 4.800;
+ int21_ar[U][A][G][C][G][G][C] = 4.800;
+ int21_ar[U][A][G][C][U][G][C] = 4.800;
+ int21_ar[U][A][G][G][A][G][C] = 1.600;
+ int21_ar[U][A][G][G][C][G][C] = 4.800;
+ int21_ar[U][A][G][G][G][G][C] = 3.000;
+ int21_ar[U][A][G][G][U][G][C] = 4.800;
+ int21_ar[U][A][G][U][A][G][C] = 4.800;
+ int21_ar[U][A][G][U][C][G][C] = 4.800;
+ int21_ar[U][A][G][U][G][G][C] = 4.800;
+ int21_ar[U][A][G][U][U][G][C] = 4.800;
+ int21_ar[U][A][U][A][A][G][C] = 4.800;
+ int21_ar[U][A][U][A][C][G][C] = 4.800;
+ int21_ar[U][A][U][A][G][G][C] = 4.800;
+ int21_ar[U][A][U][A][U][G][C] = 4.800;
+ int21_ar[U][A][U][C][A][G][C] = 4.800;
+ int21_ar[U][A][U][C][C][G][C] = 3.000;
+ int21_ar[U][A][U][C][G][G][C] = 4.800;
+ int21_ar[U][A][U][C][U][G][C] = 2.100;
+ int21_ar[U][A][U][G][A][G][C] = 4.800;
+ int21_ar[U][A][U][G][C][G][C] = 4.800;
+ int21_ar[U][A][U][G][G][G][C] = 4.800;
+ int21_ar[U][A][U][G][U][G][C] = 4.800;
+ int21_ar[U][A][U][U][A][G][C] = 4.800;
+ int21_ar[U][A][U][U][C][G][C] = 2.500;
+ int21_ar[U][A][U][U][G][G][C] = 4.800;
+ int21_ar[U][A][U][U][U][G][C] = 2.000;
+ int21_ar[U][A][A][A][A][G][U] = 3.900;
+ int21_ar[U][A][A][A][C][G][U] = 3.700;
+ int21_ar[U][A][A][A][G][G][U] = 3.100;
+ int21_ar[U][A][A][A][U][G][U] = 5.500;
+ int21_ar[U][A][A][C][A][G][U] = 3.600;
+ int21_ar[U][A][A][C][C][G][U] = 3.200;
+ int21_ar[U][A][A][C][G][G][U] = 3.100;
+ int21_ar[U][A][A][C][U][G][U] = 5.500;
+ int21_ar[U][A][A][G][A][G][U] = 2.500;
+ int21_ar[U][A][A][G][C][G][U] = 2.100;
+ int21_ar[U][A][A][G][G][G][U] = 1.900;
+ int21_ar[U][A][A][G][U][G][U] = 5.500;
+ int21_ar[U][A][A][U][A][G][U] = 5.500;
+ int21_ar[U][A][A][U][C][G][U] = 5.500;
+ int21_ar[U][A][A][U][G][G][U] = 5.500;
+ int21_ar[U][A][A][U][U][G][U] = 5.500;
+ int21_ar[U][A][C][A][A][G][U] = 3.800;
+ int21_ar[U][A][C][A][C][G][U] = 3.700;
+ int21_ar[U][A][C][A][G][G][U] = 5.500;
+ int21_ar[U][A][C][A][U][G][U] = 3.700;
+ int21_ar[U][A][C][C][A][G][U] = 3.700;
+ int21_ar[U][A][C][C][C][G][U] = 4.000;
+ int21_ar[U][A][C][C][G][G][U] = 5.500;
+ int21_ar[U][A][C][C][U][G][U] = 3.700;
+ int21_ar[U][A][C][G][A][G][U] = 5.500;
+ int21_ar[U][A][C][G][C][G][U] = 5.500;
+ int21_ar[U][A][C][G][G][G][U] = 5.500;
+ int21_ar[U][A][C][G][U][G][U] = 5.500;
+ int21_ar[U][A][C][U][A][G][U] = 4.000;
+ int21_ar[U][A][C][U][C][G][U] = 3.400;
+ int21_ar[U][A][C][U][G][G][U] = 5.500;
+ int21_ar[U][A][C][U][U][G][U] = 3.700;
+ int21_ar[U][A][G][A][A][G][U] = 3.200;
+ int21_ar[U][A][G][A][C][G][U] = 5.500;
+ int21_ar[U][A][G][A][G][G][U] = 2.300;
+ int21_ar[U][A][G][A][U][G][U] = 5.500;
+ int21_ar[U][A][G][C][A][G][U] = 5.500;
+ int21_ar[U][A][G][C][C][G][U] = 5.500;
+ int21_ar[U][A][G][C][G][G][U] = 5.500;
+ int21_ar[U][A][G][C][U][G][U] = 5.500;
+ int21_ar[U][A][G][G][A][G][U] = 2.300;
+ int21_ar[U][A][G][G][C][G][U] = 5.500;
+ int21_ar[U][A][G][G][G][G][U] = 3.700;
+ int21_ar[U][A][G][G][U][G][U] = 5.500;
+ int21_ar[U][A][G][U][A][G][U] = 5.500;
+ int21_ar[U][A][G][U][C][G][U] = 5.500;
+ int21_ar[U][A][G][U][G][G][U] = 5.500;
+ int21_ar[U][A][G][U][U][G][U] = 5.500;
+ int21_ar[U][A][U][A][A][G][U] = 5.500;
+ int21_ar[U][A][U][A][C][G][U] = 5.500;
+ int21_ar[U][A][U][A][G][G][U] = 5.500;
+ int21_ar[U][A][U][A][U][G][U] = 5.500;
+ int21_ar[U][A][U][C][A][G][U] = 5.500;
+ int21_ar[U][A][U][C][C][G][U] = 3.700;
+ int21_ar[U][A][U][C][G][G][U] = 5.500;
+ int21_ar[U][A][U][C][U][G][U] = 2.800;
+ int21_ar[U][A][U][G][A][G][U] = 5.500;
+ int21_ar[U][A][U][G][C][G][U] = 5.500;
+ int21_ar[U][A][U][G][G][G][U] = 5.500;
+ int21_ar[U][A][U][G][U][G][U] = 5.500;
+ int21_ar[U][A][U][U][A][G][U] = 5.500;
+ int21_ar[U][A][U][U][C][G][U] = 3.200;
+ int21_ar[U][A][U][U][G][G][U] = 5.500;
+ int21_ar[U][A][U][U][U][G][U] = 2.700;
+ int21_ar[U][A][A][A][A][U][A] = 3.900;
+ int21_ar[U][A][A][A][C][U][A] = 3.700;
+ int21_ar[U][A][A][A][G][U][A] = 3.100;
+ int21_ar[U][A][A][A][U][U][A] = 5.500;
+ int21_ar[U][A][A][C][A][U][A] = 3.600;
+ int21_ar[U][A][A][C][C][U][A] = 3.200;
+ int21_ar[U][A][A][C][G][U][A] = 3.100;
+ int21_ar[U][A][A][C][U][U][A] = 5.500;
+ int21_ar[U][A][A][G][A][U][A] = 2.500;
+ int21_ar[U][A][A][G][C][U][A] = 2.100;
+ int21_ar[U][A][A][G][G][U][A] = 1.900;
+ int21_ar[U][A][A][G][U][U][A] = 5.500;
+ int21_ar[U][A][A][U][A][U][A] = 5.500;
+ int21_ar[U][A][A][U][C][U][A] = 5.500;
+ int21_ar[U][A][A][U][G][U][A] = 5.500;
+ int21_ar[U][A][A][U][U][U][A] = 5.500;
+ int21_ar[U][A][C][A][A][U][A] = 3.800;
+ int21_ar[U][A][C][A][C][U][A] = 3.700;
+ int21_ar[U][A][C][A][G][U][A] = 5.500;
+ int21_ar[U][A][C][A][U][U][A] = 3.700;
+ int21_ar[U][A][C][C][A][U][A] = 3.700;
+ int21_ar[U][A][C][C][C][U][A] = 4.000;
+ int21_ar[U][A][C][C][G][U][A] = 5.500;
+ int21_ar[U][A][C][C][U][U][A] = 3.700;
+ int21_ar[U][A][C][G][A][U][A] = 5.500;
+ int21_ar[U][A][C][G][C][U][A] = 5.500;
+ int21_ar[U][A][C][G][G][U][A] = 5.500;
+ int21_ar[U][A][C][G][U][U][A] = 5.500;
+ int21_ar[U][A][C][U][A][U][A] = 4.000;
+ int21_ar[U][A][C][U][C][U][A] = 3.400;
+ int21_ar[U][A][C][U][G][U][A] = 5.500;
+ int21_ar[U][A][C][U][U][U][A] = 3.700;
+ int21_ar[U][A][G][A][A][U][A] = 3.200;
+ int21_ar[U][A][G][A][C][U][A] = 5.500;
+ int21_ar[U][A][G][A][G][U][A] = 2.300;
+ int21_ar[U][A][G][A][U][U][A] = 5.500;
+ int21_ar[U][A][G][C][A][U][A] = 5.500;
+ int21_ar[U][A][G][C][C][U][A] = 5.500;
+ int21_ar[U][A][G][C][G][U][A] = 5.500;
+ int21_ar[U][A][G][C][U][U][A] = 5.500;
+ int21_ar[U][A][G][G][A][U][A] = 2.300;
+ int21_ar[U][A][G][G][C][U][A] = 5.500;
+ int21_ar[U][A][G][G][G][U][A] = 3.700;
+ int21_ar[U][A][G][G][U][U][A] = 5.500;
+ int21_ar[U][A][G][U][A][U][A] = 5.500;
+ int21_ar[U][A][G][U][C][U][A] = 5.500;
+ int21_ar[U][A][G][U][G][U][A] = 5.500;
+ int21_ar[U][A][G][U][U][U][A] = 5.500;
+ int21_ar[U][A][U][A][A][U][A] = 5.500;
+ int21_ar[U][A][U][A][C][U][A] = 5.500;
+ int21_ar[U][A][U][A][G][U][A] = 5.500;
+ int21_ar[U][A][U][A][U][U][A] = 5.500;
+ int21_ar[U][A][U][C][A][U][A] = 5.500;
+ int21_ar[U][A][U][C][C][U][A] = 3.700;
+ int21_ar[U][A][U][C][G][U][A] = 5.500;
+ int21_ar[U][A][U][C][U][U][A] = 2.800;
+ int21_ar[U][A][U][G][A][U][A] = 5.500;
+ int21_ar[U][A][U][G][C][U][A] = 5.500;
+ int21_ar[U][A][U][G][G][U][A] = 5.500;
+ int21_ar[U][A][U][G][U][U][A] = 5.500;
+ int21_ar[U][A][U][U][A][U][A] = 5.500;
+ int21_ar[U][A][U][U][C][U][A] = 3.200;
+ int21_ar[U][A][U][U][G][U][A] = 5.500;
+ int21_ar[U][A][U][U][U][U][A] = 2.700;
+ int21_ar[U][A][A][A][A][U][G] = 3.900;
+ int21_ar[U][A][A][A][C][U][G] = 3.700;
+ int21_ar[U][A][A][A][G][U][G] = 3.100;
+ int21_ar[U][A][A][A][U][U][G] = 5.500;
+ int21_ar[U][A][A][C][A][U][G] = 3.600;
+ int21_ar[U][A][A][C][C][U][G] = 3.200;
+ int21_ar[U][A][A][C][G][U][G] = 3.100;
+ int21_ar[U][A][A][C][U][U][G] = 5.500;
+ int21_ar[U][A][A][G][A][U][G] = 2.500;
+ int21_ar[U][A][A][G][C][U][G] = 2.100;
+ int21_ar[U][A][A][G][G][U][G] = 1.900;
+ int21_ar[U][A][A][G][U][U][G] = 5.500;
+ int21_ar[U][A][A][U][A][U][G] = 5.500;
+ int21_ar[U][A][A][U][C][U][G] = 5.500;
+ int21_ar[U][A][A][U][G][U][G] = 5.500;
+ int21_ar[U][A][A][U][U][U][G] = 5.500;
+ int21_ar[U][A][C][A][A][U][G] = 3.800;
+ int21_ar[U][A][C][A][C][U][G] = 3.700;
+ int21_ar[U][A][C][A][G][U][G] = 5.500;
+ int21_ar[U][A][C][A][U][U][G] = 3.700;
+ int21_ar[U][A][C][C][A][U][G] = 3.700;
+ int21_ar[U][A][C][C][C][U][G] = 4.000;
+ int21_ar[U][A][C][C][G][U][G] = 5.500;
+ int21_ar[U][A][C][C][U][U][G] = 3.700;
+ int21_ar[U][A][C][G][A][U][G] = 5.500;
+ int21_ar[U][A][C][G][C][U][G] = 5.500;
+ int21_ar[U][A][C][G][G][U][G] = 5.500;
+ int21_ar[U][A][C][G][U][U][G] = 5.500;
+ int21_ar[U][A][C][U][A][U][G] = 4.000;
+ int21_ar[U][A][C][U][C][U][G] = 3.400;
+ int21_ar[U][A][C][U][G][U][G] = 5.500;
+ int21_ar[U][A][C][U][U][U][G] = 3.700;
+ int21_ar[U][A][G][A][A][U][G] = 3.200;
+ int21_ar[U][A][G][A][C][U][G] = 5.500;
+ int21_ar[U][A][G][A][G][U][G] = 2.300;
+ int21_ar[U][A][G][A][U][U][G] = 5.500;
+ int21_ar[U][A][G][C][A][U][G] = 5.500;
+ int21_ar[U][A][G][C][C][U][G] = 5.500;
+ int21_ar[U][A][G][C][G][U][G] = 5.500;
+ int21_ar[U][A][G][C][U][U][G] = 5.500;
+ int21_ar[U][A][G][G][A][U][G] = 2.300;
+ int21_ar[U][A][G][G][C][U][G] = 5.500;
+ int21_ar[U][A][G][G][G][U][G] = 3.700;
+ int21_ar[U][A][G][G][U][U][G] = 5.500;
+ int21_ar[U][A][G][U][A][U][G] = 5.500;
+ int21_ar[U][A][G][U][C][U][G] = 5.500;
+ int21_ar[U][A][G][U][G][U][G] = 5.500;
+ int21_ar[U][A][G][U][U][U][G] = 5.500;
+ int21_ar[U][A][U][A][A][U][G] = 5.500;
+ int21_ar[U][A][U][A][C][U][G] = 5.500;
+ int21_ar[U][A][U][A][G][U][G] = 5.500;
+ int21_ar[U][A][U][A][U][U][G] = 5.500;
+ int21_ar[U][A][U][C][A][U][G] = 5.500;
+ int21_ar[U][A][U][C][C][U][G] = 3.700;
+ int21_ar[U][A][U][C][G][U][G] = 5.500;
+ int21_ar[U][A][U][C][U][U][G] = 2.800;
+ int21_ar[U][A][U][G][A][U][G] = 5.500;
+ int21_ar[U][A][U][G][C][U][G] = 5.500;
+ int21_ar[U][A][U][G][G][U][G] = 5.500;
+ int21_ar[U][A][U][G][U][U][G] = 5.500;
+ int21_ar[U][A][U][U][A][U][G] = 5.500;
+ int21_ar[U][A][U][U][C][U][G] = 3.200;
+ int21_ar[U][A][U][U][G][U][G] = 5.500;
+ int21_ar[U][A][U][U][U][U][G] = 2.700;
+ int21_ar[U][G][A][A][A][A][U] = 3.900;
+ int21_ar[U][G][A][A][C][A][U] = 3.700;
+ int21_ar[U][G][A][A][G][A][U] = 3.100;
+ int21_ar[U][G][A][A][U][A][U] = 5.500;
+ int21_ar[U][G][A][C][A][A][U] = 3.600;
+ int21_ar[U][G][A][C][C][A][U] = 3.200;
+ int21_ar[U][G][A][C][G][A][U] = 3.100;
+ int21_ar[U][G][A][C][U][A][U] = 5.500;
+ int21_ar[U][G][A][G][A][A][U] = 2.500;
+ int21_ar[U][G][A][G][C][A][U] = 2.100;
+ int21_ar[U][G][A][G][G][A][U] = 1.900;
+ int21_ar[U][G][A][G][U][A][U] = 5.500;
+ int21_ar[U][G][A][U][A][A][U] = 5.500;
+ int21_ar[U][G][A][U][C][A][U] = 5.500;
+ int21_ar[U][G][A][U][G][A][U] = 5.500;
+ int21_ar[U][G][A][U][U][A][U] = 5.500;
+ int21_ar[U][G][C][A][A][A][U] = 3.800;
+ int21_ar[U][G][C][A][C][A][U] = 3.700;
+ int21_ar[U][G][C][A][G][A][U] = 5.500;
+ int21_ar[U][G][C][A][U][A][U] = 3.700;
+ int21_ar[U][G][C][C][A][A][U] = 3.700;
+ int21_ar[U][G][C][C][C][A][U] = 4.000;
+ int21_ar[U][G][C][C][G][A][U] = 5.500;
+ int21_ar[U][G][C][C][U][A][U] = 3.700;
+ int21_ar[U][G][C][G][A][A][U] = 5.500;
+ int21_ar[U][G][C][G][C][A][U] = 5.500;
+ int21_ar[U][G][C][G][G][A][U] = 5.500;
+ int21_ar[U][G][C][G][U][A][U] = 5.500;
+ int21_ar[U][G][C][U][A][A][U] = 4.000;
+ int21_ar[U][G][C][U][C][A][U] = 3.400;
+ int21_ar[U][G][C][U][G][A][U] = 5.500;
+ int21_ar[U][G][C][U][U][A][U] = 3.700;
+ int21_ar[U][G][G][A][A][A][U] = 3.200;
+ int21_ar[U][G][G][A][C][A][U] = 5.500;
+ int21_ar[U][G][G][A][G][A][U] = 2.300;
+ int21_ar[U][G][G][A][U][A][U] = 5.500;
+ int21_ar[U][G][G][C][A][A][U] = 5.500;
+ int21_ar[U][G][G][C][C][A][U] = 5.500;
+ int21_ar[U][G][G][C][G][A][U] = 5.500;
+ int21_ar[U][G][G][C][U][A][U] = 5.500;
+ int21_ar[U][G][G][G][A][A][U] = 2.300;
+ int21_ar[U][G][G][G][C][A][U] = 5.500;
+ int21_ar[U][G][G][G][G][A][U] = 3.700;
+ int21_ar[U][G][G][G][U][A][U] = 5.500;
+ int21_ar[U][G][G][U][A][A][U] = 5.500;
+ int21_ar[U][G][G][U][C][A][U] = 5.500;
+ int21_ar[U][G][G][U][G][A][U] = 5.500;
+ int21_ar[U][G][G][U][U][A][U] = 5.500;
+ int21_ar[U][G][U][A][A][A][U] = 5.500;
+ int21_ar[U][G][U][A][C][A][U] = 5.500;
+ int21_ar[U][G][U][A][G][A][U] = 5.500;
+ int21_ar[U][G][U][A][U][A][U] = 5.500;
+ int21_ar[U][G][U][C][A][A][U] = 5.500;
+ int21_ar[U][G][U][C][C][A][U] = 3.700;
+ int21_ar[U][G][U][C][G][A][U] = 5.500;
+ int21_ar[U][G][U][C][U][A][U] = 2.800;
+ int21_ar[U][G][U][G][A][A][U] = 5.500;
+ int21_ar[U][G][U][G][C][A][U] = 5.500;
+ int21_ar[U][G][U][G][G][A][U] = 5.500;
+ int21_ar[U][G][U][G][U][A][U] = 5.500;
+ int21_ar[U][G][U][U][A][A][U] = 5.500;
+ int21_ar[U][G][U][U][C][A][U] = 3.200;
+ int21_ar[U][G][U][U][G][A][U] = 5.500;
+ int21_ar[U][G][U][U][U][A][U] = 2.700;
+ int21_ar[U][G][A][A][A][C][G] = 3.200;
+ int21_ar[U][G][A][A][C][C][G] = 3.000;
+ int21_ar[U][G][A][A][G][C][G] = 2.400;
+ int21_ar[U][G][A][A][U][C][G] = 4.800;
+ int21_ar[U][G][A][C][A][C][G] = 2.900;
+ int21_ar[U][G][A][C][C][C][G] = 2.500;
+ int21_ar[U][G][A][C][G][C][G] = 2.400;
+ int21_ar[U][G][A][C][U][C][G] = 4.800;
+ int21_ar[U][G][A][G][A][C][G] = 1.800;
+ int21_ar[U][G][A][G][C][C][G] = 1.400;
+ int21_ar[U][G][A][G][G][C][G] = 1.200;
+ int21_ar[U][G][A][G][U][C][G] = 4.800;
+ int21_ar[U][G][A][U][A][C][G] = 4.800;
+ int21_ar[U][G][A][U][C][C][G] = 4.800;
+ int21_ar[U][G][A][U][G][C][G] = 4.800;
+ int21_ar[U][G][A][U][U][C][G] = 4.800;
+ int21_ar[U][G][C][A][A][C][G] = 3.100;
+ int21_ar[U][G][C][A][C][C][G] = 3.000;
+ int21_ar[U][G][C][A][G][C][G] = 4.800;
+ int21_ar[U][G][C][A][U][C][G] = 3.000;
+ int21_ar[U][G][C][C][A][C][G] = 3.000;
+ int21_ar[U][G][C][C][C][C][G] = 3.300;
+ int21_ar[U][G][C][C][G][C][G] = 4.800;
+ int21_ar[U][G][C][C][U][C][G] = 3.000;
+ int21_ar[U][G][C][G][A][C][G] = 4.800;
+ int21_ar[U][G][C][G][C][C][G] = 4.800;
+ int21_ar[U][G][C][G][G][C][G] = 4.800;
+ int21_ar[U][G][C][G][U][C][G] = 4.800;
+ int21_ar[U][G][C][U][A][C][G] = 3.300;
+ int21_ar[U][G][C][U][C][C][G] = 2.700;
+ int21_ar[U][G][C][U][G][C][G] = 4.800;
+ int21_ar[U][G][C][U][U][C][G] = 3.000;
+ int21_ar[U][G][G][A][A][C][G] = 2.500;
+ int21_ar[U][G][G][A][C][C][G] = 4.800;
+ int21_ar[U][G][G][A][G][C][G] = 1.600;
+ int21_ar[U][G][G][A][U][C][G] = 4.800;
+ int21_ar[U][G][G][C][A][C][G] = 4.800;
+ int21_ar[U][G][G][C][C][C][G] = 4.800;
+ int21_ar[U][G][G][C][G][C][G] = 4.800;
+ int21_ar[U][G][G][C][U][C][G] = 4.800;
+ int21_ar[U][G][G][G][A][C][G] = 1.600;
+ int21_ar[U][G][G][G][C][C][G] = 4.800;
+ int21_ar[U][G][G][G][G][C][G] = 3.000;
+ int21_ar[U][G][G][G][U][C][G] = 4.800;
+ int21_ar[U][G][G][U][A][C][G] = 4.800;
+ int21_ar[U][G][G][U][C][C][G] = 4.800;
+ int21_ar[U][G][G][U][G][C][G] = 4.800;
+ int21_ar[U][G][G][U][U][C][G] = 4.800;
+ int21_ar[U][G][U][A][A][C][G] = 4.800;
+ int21_ar[U][G][U][A][C][C][G] = 4.800;
+ int21_ar[U][G][U][A][G][C][G] = 4.800;
+ int21_ar[U][G][U][A][U][C][G] = 4.800;
+ int21_ar[U][G][U][C][A][C][G] = 4.800;
+ int21_ar[U][G][U][C][C][C][G] = 3.000;
+ int21_ar[U][G][U][C][G][C][G] = 4.800;
+ int21_ar[U][G][U][C][U][C][G] = 2.100;
+ int21_ar[U][G][U][G][A][C][G] = 4.800;
+ int21_ar[U][G][U][G][C][C][G] = 4.800;
+ int21_ar[U][G][U][G][G][C][G] = 4.800;
+ int21_ar[U][G][U][G][U][C][G] = 4.800;
+ int21_ar[U][G][U][U][A][C][G] = 4.800;
+ int21_ar[U][G][U][U][C][C][G] = 2.500;
+ int21_ar[U][G][U][U][G][C][G] = 4.800;
+ int21_ar[U][G][U][U][U][C][G] = 2.000;
+ int21_ar[U][G][A][A][A][G][C] = 3.200;
+ int21_ar[U][G][A][A][C][G][C] = 3.000;
+ int21_ar[U][G][A][A][G][G][C] = 2.400;
+ int21_ar[U][G][A][A][U][G][C] = 4.800;
+ int21_ar[U][G][A][C][A][G][C] = 2.900;
+ int21_ar[U][G][A][C][C][G][C] = 2.500;
+ int21_ar[U][G][A][C][G][G][C] = 2.400;
+ int21_ar[U][G][A][C][U][G][C] = 4.800;
+ int21_ar[U][G][A][G][A][G][C] = 1.800;
+ int21_ar[U][G][A][G][C][G][C] = 1.400;
+ int21_ar[U][G][A][G][G][G][C] = 1.200;
+ int21_ar[U][G][A][G][U][G][C] = 4.800;
+ int21_ar[U][G][A][U][A][G][C] = 4.800;
+ int21_ar[U][G][A][U][C][G][C] = 4.800;
+ int21_ar[U][G][A][U][G][G][C] = 4.800;
+ int21_ar[U][G][A][U][U][G][C] = 4.800;
+ int21_ar[U][G][C][A][A][G][C] = 3.100;
+ int21_ar[U][G][C][A][C][G][C] = 3.000;
+ int21_ar[U][G][C][A][G][G][C] = 4.800;
+ int21_ar[U][G][C][A][U][G][C] = 3.000;
+ int21_ar[U][G][C][C][A][G][C] = 3.000;
+ int21_ar[U][G][C][C][C][G][C] = 3.300;
+ int21_ar[U][G][C][C][G][G][C] = 4.800;
+ int21_ar[U][G][C][C][U][G][C] = 3.000;
+ int21_ar[U][G][C][G][A][G][C] = 4.800;
+ int21_ar[U][G][C][G][C][G][C] = 4.800;
+ int21_ar[U][G][C][G][G][G][C] = 4.800;
+ int21_ar[U][G][C][G][U][G][C] = 4.800;
+ int21_ar[U][G][C][U][A][G][C] = 3.300;
+ int21_ar[U][G][C][U][C][G][C] = 2.700;
+ int21_ar[U][G][C][U][G][G][C] = 4.800;
+ int21_ar[U][G][C][U][U][G][C] = 3.000;
+ int21_ar[U][G][G][A][A][G][C] = 2.500;
+ int21_ar[U][G][G][A][C][G][C] = 4.800;
+ int21_ar[U][G][G][A][G][G][C] = 1.600;
+ int21_ar[U][G][G][A][U][G][C] = 4.800;
+ int21_ar[U][G][G][C][A][G][C] = 4.800;
+ int21_ar[U][G][G][C][C][G][C] = 4.800;
+ int21_ar[U][G][G][C][G][G][C] = 4.800;
+ int21_ar[U][G][G][C][U][G][C] = 4.800;
+ int21_ar[U][G][G][G][A][G][C] = 1.600;
+ int21_ar[U][G][G][G][C][G][C] = 4.800;
+ int21_ar[U][G][G][G][G][G][C] = 3.000;
+ int21_ar[U][G][G][G][U][G][C] = 4.800;
+ int21_ar[U][G][G][U][A][G][C] = 4.800;
+ int21_ar[U][G][G][U][C][G][C] = 4.800;
+ int21_ar[U][G][G][U][G][G][C] = 4.800;
+ int21_ar[U][G][G][U][U][G][C] = 4.800;
+ int21_ar[U][G][U][A][A][G][C] = 4.800;
+ int21_ar[U][G][U][A][C][G][C] = 4.800;
+ int21_ar[U][G][U][A][G][G][C] = 4.800;
+ int21_ar[U][G][U][A][U][G][C] = 4.800;
+ int21_ar[U][G][U][C][A][G][C] = 4.800;
+ int21_ar[U][G][U][C][C][G][C] = 3.000;
+ int21_ar[U][G][U][C][G][G][C] = 4.800;
+ int21_ar[U][G][U][C][U][G][C] = 2.100;
+ int21_ar[U][G][U][G][A][G][C] = 4.800;
+ int21_ar[U][G][U][G][C][G][C] = 4.800;
+ int21_ar[U][G][U][G][G][G][C] = 4.800;
+ int21_ar[U][G][U][G][U][G][C] = 4.800;
+ int21_ar[U][G][U][U][A][G][C] = 4.800;
+ int21_ar[U][G][U][U][C][G][C] = 2.500;
+ int21_ar[U][G][U][U][G][G][C] = 4.800;
+ int21_ar[U][G][U][U][U][G][C] = 2.000;
+ int21_ar[U][G][A][A][A][G][U] = 3.900;
+ int21_ar[U][G][A][A][C][G][U] = 3.700;
+ int21_ar[U][G][A][A][G][G][U] = 3.100;
+ int21_ar[U][G][A][A][U][G][U] = 5.500;
+ int21_ar[U][G][A][C][A][G][U] = 3.600;
+ int21_ar[U][G][A][C][C][G][U] = 3.200;
+ int21_ar[U][G][A][C][G][G][U] = 3.100;
+ int21_ar[U][G][A][C][U][G][U] = 5.500;
+ int21_ar[U][G][A][G][A][G][U] = 2.500;
+ int21_ar[U][G][A][G][C][G][U] = 2.100;
+ int21_ar[U][G][A][G][G][G][U] = 1.900;
+ int21_ar[U][G][A][G][U][G][U] = 5.500;
+ int21_ar[U][G][A][U][A][G][U] = 5.500;
+ int21_ar[U][G][A][U][C][G][U] = 5.500;
+ int21_ar[U][G][A][U][G][G][U] = 5.500;
+ int21_ar[U][G][A][U][U][G][U] = 5.500;
+ int21_ar[U][G][C][A][A][G][U] = 3.800;
+ int21_ar[U][G][C][A][C][G][U] = 3.700;
+ int21_ar[U][G][C][A][G][G][U] = 5.500;
+ int21_ar[U][G][C][A][U][G][U] = 3.700;
+ int21_ar[U][G][C][C][A][G][U] = 3.700;
+ int21_ar[U][G][C][C][C][G][U] = 4.000;
+ int21_ar[U][G][C][C][G][G][U] = 5.500;
+ int21_ar[U][G][C][C][U][G][U] = 3.700;
+ int21_ar[U][G][C][G][A][G][U] = 5.500;
+ int21_ar[U][G][C][G][C][G][U] = 5.500;
+ int21_ar[U][G][C][G][G][G][U] = 5.500;
+ int21_ar[U][G][C][G][U][G][U] = 5.500;
+ int21_ar[U][G][C][U][A][G][U] = 4.000;
+ int21_ar[U][G][C][U][C][G][U] = 3.400;
+ int21_ar[U][G][C][U][G][G][U] = 5.500;
+ int21_ar[U][G][C][U][U][G][U] = 3.700;
+ int21_ar[U][G][G][A][A][G][U] = 3.200;
+ int21_ar[U][G][G][A][C][G][U] = 5.500;
+ int21_ar[U][G][G][A][G][G][U] = 2.300;
+ int21_ar[U][G][G][A][U][G][U] = 5.500;
+ int21_ar[U][G][G][C][A][G][U] = 5.500;
+ int21_ar[U][G][G][C][C][G][U] = 5.500;
+ int21_ar[U][G][G][C][G][G][U] = 5.500;
+ int21_ar[U][G][G][C][U][G][U] = 5.500;
+ int21_ar[U][G][G][G][A][G][U] = 2.300;
+ int21_ar[U][G][G][G][C][G][U] = 5.500;
+ int21_ar[U][G][G][G][G][G][U] = 3.700;
+ int21_ar[U][G][G][G][U][G][U] = 5.500;
+ int21_ar[U][G][G][U][A][G][U] = 5.500;
+ int21_ar[U][G][G][U][C][G][U] = 5.500;
+ int21_ar[U][G][G][U][G][G][U] = 5.500;
+ int21_ar[U][G][G][U][U][G][U] = 5.500;
+ int21_ar[U][G][U][A][A][G][U] = 5.500;
+ int21_ar[U][G][U][A][C][G][U] = 5.500;
+ int21_ar[U][G][U][A][G][G][U] = 5.500;
+ int21_ar[U][G][U][A][U][G][U] = 5.500;
+ int21_ar[U][G][U][C][A][G][U] = 5.500;
+ int21_ar[U][G][U][C][C][G][U] = 3.700;
+ int21_ar[U][G][U][C][G][G][U] = 5.500;
+ int21_ar[U][G][U][C][U][G][U] = 2.800;
+ int21_ar[U][G][U][G][A][G][U] = 5.500;
+ int21_ar[U][G][U][G][C][G][U] = 5.500;
+ int21_ar[U][G][U][G][G][G][U] = 5.500;
+ int21_ar[U][G][U][G][U][G][U] = 5.500;
+ int21_ar[U][G][U][U][A][G][U] = 5.500;
+ int21_ar[U][G][U][U][C][G][U] = 3.200;
+ int21_ar[U][G][U][U][G][G][U] = 5.500;
+ int21_ar[U][G][U][U][U][G][U] = 2.700;
+ int21_ar[U][G][A][A][A][U][A] = 3.900;
+ int21_ar[U][G][A][A][C][U][A] = 3.700;
+ int21_ar[U][G][A][A][G][U][A] = 3.100;
+ int21_ar[U][G][A][A][U][U][A] = 5.500;
+ int21_ar[U][G][A][C][A][U][A] = 3.600;
+ int21_ar[U][G][A][C][C][U][A] = 3.200;
+ int21_ar[U][G][A][C][G][U][A] = 3.100;
+ int21_ar[U][G][A][C][U][U][A] = 5.500;
+ int21_ar[U][G][A][G][A][U][A] = 2.500;
+ int21_ar[U][G][A][G][C][U][A] = 2.100;
+ int21_ar[U][G][A][G][G][U][A] = 1.900;
+ int21_ar[U][G][A][G][U][U][A] = 5.500;
+ int21_ar[U][G][A][U][A][U][A] = 5.500;
+ int21_ar[U][G][A][U][C][U][A] = 5.500;
+ int21_ar[U][G][A][U][G][U][A] = 5.500;
+ int21_ar[U][G][A][U][U][U][A] = 5.500;
+ int21_ar[U][G][C][A][A][U][A] = 3.800;
+ int21_ar[U][G][C][A][C][U][A] = 3.700;
+ int21_ar[U][G][C][A][G][U][A] = 5.500;
+ int21_ar[U][G][C][A][U][U][A] = 3.700;
+ int21_ar[U][G][C][C][A][U][A] = 3.700;
+ int21_ar[U][G][C][C][C][U][A] = 4.000;
+ int21_ar[U][G][C][C][G][U][A] = 5.500;
+ int21_ar[U][G][C][C][U][U][A] = 3.700;
+ int21_ar[U][G][C][G][A][U][A] = 5.500;
+ int21_ar[U][G][C][G][C][U][A] = 5.500;
+ int21_ar[U][G][C][G][G][U][A] = 5.500;
+ int21_ar[U][G][C][G][U][U][A] = 5.500;
+ int21_ar[U][G][C][U][A][U][A] = 4.000;
+ int21_ar[U][G][C][U][C][U][A] = 3.400;
+ int21_ar[U][G][C][U][G][U][A] = 5.500;
+ int21_ar[U][G][C][U][U][U][A] = 3.700;
+ int21_ar[U][G][G][A][A][U][A] = 3.200;
+ int21_ar[U][G][G][A][C][U][A] = 5.500;
+ int21_ar[U][G][G][A][G][U][A] = 2.300;
+ int21_ar[U][G][G][A][U][U][A] = 5.500;
+ int21_ar[U][G][G][C][A][U][A] = 5.500;
+ int21_ar[U][G][G][C][C][U][A] = 5.500;
+ int21_ar[U][G][G][C][G][U][A] = 5.500;
+ int21_ar[U][G][G][C][U][U][A] = 5.500;
+ int21_ar[U][G][G][G][A][U][A] = 2.300;
+ int21_ar[U][G][G][G][C][U][A] = 5.500;
+ int21_ar[U][G][G][G][G][U][A] = 3.700;
+ int21_ar[U][G][G][G][U][U][A] = 5.500;
+ int21_ar[U][G][G][U][A][U][A] = 5.500;
+ int21_ar[U][G][G][U][C][U][A] = 5.500;
+ int21_ar[U][G][G][U][G][U][A] = 5.500;
+ int21_ar[U][G][G][U][U][U][A] = 5.500;
+ int21_ar[U][G][U][A][A][U][A] = 5.500;
+ int21_ar[U][G][U][A][C][U][A] = 5.500;
+ int21_ar[U][G][U][A][G][U][A] = 5.500;
+ int21_ar[U][G][U][A][U][U][A] = 5.500;
+ int21_ar[U][G][U][C][A][U][A] = 5.500;
+ int21_ar[U][G][U][C][C][U][A] = 3.700;
+ int21_ar[U][G][U][C][G][U][A] = 5.500;
+ int21_ar[U][G][U][C][U][U][A] = 2.800;
+ int21_ar[U][G][U][G][A][U][A] = 5.500;
+ int21_ar[U][G][U][G][C][U][A] = 5.500;
+ int21_ar[U][G][U][G][G][U][A] = 5.500;
+ int21_ar[U][G][U][G][U][U][A] = 5.500;
+ int21_ar[U][G][U][U][A][U][A] = 5.500;
+ int21_ar[U][G][U][U][C][U][A] = 3.200;
+ int21_ar[U][G][U][U][G][U][A] = 5.500;
+ int21_ar[U][G][U][U][U][U][A] = 2.700;
+ int21_ar[U][G][A][A][A][U][G] = 3.900;
+ int21_ar[U][G][A][A][C][U][G] = 3.700;
+ int21_ar[U][G][A][A][G][U][G] = 3.100;
+ int21_ar[U][G][A][A][U][U][G] = 5.500;
+ int21_ar[U][G][A][C][A][U][G] = 3.600;
+ int21_ar[U][G][A][C][C][U][G] = 3.200;
+ int21_ar[U][G][A][C][G][U][G] = 3.100;
+ int21_ar[U][G][A][C][U][U][G] = 5.500;
+ int21_ar[U][G][A][G][A][U][G] = 2.500;
+ int21_ar[U][G][A][G][C][U][G] = 2.100;
+ int21_ar[U][G][A][G][G][U][G] = 1.900;
+ int21_ar[U][G][A][G][U][U][G] = 5.500;
+ int21_ar[U][G][A][U][A][U][G] = 5.500;
+ int21_ar[U][G][A][U][C][U][G] = 5.500;
+ int21_ar[U][G][A][U][G][U][G] = 5.500;
+ int21_ar[U][G][A][U][U][U][G] = 5.500;
+ int21_ar[U][G][C][A][A][U][G] = 3.800;
+ int21_ar[U][G][C][A][C][U][G] = 3.700;
+ int21_ar[U][G][C][A][G][U][G] = 5.500;
+ int21_ar[U][G][C][A][U][U][G] = 3.700;
+ int21_ar[U][G][C][C][A][U][G] = 3.700;
+ int21_ar[U][G][C][C][C][U][G] = 4.000;
+ int21_ar[U][G][C][C][G][U][G] = 5.500;
+ int21_ar[U][G][C][C][U][U][G] = 3.700;
+ int21_ar[U][G][C][G][A][U][G] = 5.500;
+ int21_ar[U][G][C][G][C][U][G] = 5.500;
+ int21_ar[U][G][C][G][G][U][G] = 5.500;
+ int21_ar[U][G][C][G][U][U][G] = 5.500;
+ int21_ar[U][G][C][U][A][U][G] = 4.000;
+ int21_ar[U][G][C][U][C][U][G] = 3.400;
+ int21_ar[U][G][C][U][G][U][G] = 5.500;
+ int21_ar[U][G][C][U][U][U][G] = 3.700;
+ int21_ar[U][G][G][A][A][U][G] = 3.200;
+ int21_ar[U][G][G][A][C][U][G] = 5.500;
+ int21_ar[U][G][G][A][G][U][G] = 2.300;
+ int21_ar[U][G][G][A][U][U][G] = 5.500;
+ int21_ar[U][G][G][C][A][U][G] = 5.500;
+ int21_ar[U][G][G][C][C][U][G] = 5.500;
+ int21_ar[U][G][G][C][G][U][G] = 5.500;
+ int21_ar[U][G][G][C][U][U][G] = 5.500;
+ int21_ar[U][G][G][G][A][U][G] = 2.300;
+ int21_ar[U][G][G][G][C][U][G] = 5.500;
+ int21_ar[U][G][G][G][G][U][G] = 3.700;
+ int21_ar[U][G][G][G][U][U][G] = 5.500;
+ int21_ar[U][G][G][U][A][U][G] = 5.500;
+ int21_ar[U][G][G][U][C][U][G] = 5.500;
+ int21_ar[U][G][G][U][G][U][G] = 5.500;
+ int21_ar[U][G][G][U][U][U][G] = 5.500;
+ int21_ar[U][G][U][A][A][U][G] = 5.500;
+ int21_ar[U][G][U][A][C][U][G] = 5.500;
+ int21_ar[U][G][U][A][G][U][G] = 5.500;
+ int21_ar[U][G][U][A][U][U][G] = 5.500;
+ int21_ar[U][G][U][C][A][U][G] = 5.500;
+ int21_ar[U][G][U][C][C][U][G] = 3.700;
+ int21_ar[U][G][U][C][G][U][G] = 5.500;
+ int21_ar[U][G][U][C][U][U][G] = 2.800;
+ int21_ar[U][G][U][G][A][U][G] = 5.500;
+ int21_ar[U][G][U][G][C][U][G] = 5.500;
+ int21_ar[U][G][U][G][G][U][G] = 5.500;
+ int21_ar[U][G][U][G][U][U][G] = 5.500;
+ int21_ar[U][G][U][U][A][U][G] = 5.500;
+ int21_ar[U][G][U][U][C][U][G] = 3.200;
+ int21_ar[U][G][U][U][G][U][G] = 5.500;
+ int21_ar[U][G][U][U][U][U][G] = 2.700;
+}
+
+void init_int22_ar()
+{
+ int k1,k2,k3,k4,k5,k6,k7,k8;
+
+ for (k1=0;k1<ALPHASIZE;k1++)
+ for (k2=0;k2<ALPHASIZE;k2++)
+ for (k3=0;k3<ALPHASIZE;k3++)
+ for (k4=0;k4<ALPHASIZE;k4++)
+ for (k5=0;k5<ALPHASIZE;k5++)
+ for (k6=0;k6<ALPHASIZE;k6++)
+ for (k7=0;k7<ALPHASIZE;k7++)
+ for (k8=0;k8<ALPHASIZE;k8++)
+ int22_ar[k1][k2][k3][k4][k5][k6][k7][k8]=0.0;
+
+ int22_ar[A][U][A][A][A][A][A][U] = 2.800;
+ int22_ar[A][U][A][A][A][C][A][U] = 2.600;
+ int22_ar[A][U][A][A][A][G][A][U] = 1.500;
+ int22_ar[A][U][A][A][A][U][A][U] = 2.000;
+ int22_ar[A][U][A][A][C][A][A][U] = 2.500;
+ int22_ar[A][U][A][A][C][C][A][U] = 2.400;
+ int22_ar[A][U][A][A][C][G][A][U] = 1.300;
+ int22_ar[A][U][A][A][C][U][A][U] = 2.000;
+ int22_ar[A][U][A][A][G][A][A][U] = 1.500;
+ int22_ar[A][U][A][A][G][C][A][U] = 1.400;
+ int22_ar[A][U][A][A][G][G][A][U] = 0.300;
+ int22_ar[A][U][A][A][G][U][A][U] = 2.000;
+ int22_ar[A][U][A][A][U][A][A][U] = 2.000;
+ int22_ar[A][U][A][A][U][C][A][U] = 2.000;
+ int22_ar[A][U][A][A][U][G][A][U] = 2.000;
+ int22_ar[A][U][A][A][U][U][A][U] = 2.000;
+ int22_ar[A][U][A][C][A][A][A][U] = 2.600;
+ int22_ar[A][U][A][C][A][C][A][U] = 2.500;
+ int22_ar[A][U][A][C][A][G][A][U] = 1.400;
+ int22_ar[A][U][A][C][A][U][A][U] = 2.000;
+ int22_ar[A][U][A][C][C][A][A][U] = 3.100;
+ int22_ar[A][U][A][C][C][C][A][U] = 2.300;
+ int22_ar[A][U][A][C][C][G][A][U] = 2.200;
+ int22_ar[A][U][A][C][C][U][A][U] = 2.000;
+ int22_ar[A][U][A][C][G][A][A][U] = 2.000;
+ int22_ar[A][U][A][C][G][C][A][U] = 2.000;
+ int22_ar[A][U][A][C][G][G][A][U] = 2.000;
+ int22_ar[A][U][A][C][G][U][A][U] = 2.000;
+ int22_ar[A][U][A][C][U][A][A][U] = 3.100;
+ int22_ar[A][U][A][C][U][C][A][U] = 2.300;
+ int22_ar[A][U][A][C][U][G][A][U] = 2.200;
+ int22_ar[A][U][A][C][U][U][A][U] = 2.000;
+ int22_ar[A][U][A][G][A][A][A][U] = 1.500;
+ int22_ar[A][U][A][G][A][C][A][U] = 1.400;
+ int22_ar[A][U][A][G][A][G][A][U] = 0.300;
+ int22_ar[A][U][A][G][A][U][A][U] = 2.000;
+ int22_ar[A][U][A][G][C][A][A][U] = 2.000;
+ int22_ar[A][U][A][G][C][C][A][U] = 2.000;
+ int22_ar[A][U][A][G][C][G][A][U] = 2.000;
+ int22_ar[A][U][A][G][C][U][A][U] = 2.000;
+ int22_ar[A][U][A][G][G][A][A][U] = 2.100;
+ int22_ar[A][U][A][G][G][C][A][U] = 1.900;
+ int22_ar[A][U][A][G][G][G][A][U] = 0.800;
+ int22_ar[A][U][A][G][G][U][A][U] = 2.000;
+ int22_ar[A][U][A][G][U][A][A][U] = 1.300;
+ int22_ar[A][U][A][G][U][C][A][U] = 0.200;
+ int22_ar[A][U][A][G][U][G][A][U] = 0.900;
+ int22_ar[A][U][A][G][U][U][A][U] = 2.000;
+ int22_ar[A][U][A][U][A][A][A][U] = 2.000;
+ int22_ar[A][U][A][U][A][C][A][U] = 2.000;
+ int22_ar[A][U][A][U][A][G][A][U] = 2.000;
+ int22_ar[A][U][A][U][A][U][A][U] = 2.000;
+ int22_ar[A][U][A][U][C][A][A][U] = 3.100;
+ int22_ar[A][U][A][U][C][C][A][U] = 2.300;
+ int22_ar[A][U][A][U][C][G][A][U] = 2.200;
+ int22_ar[A][U][A][U][C][U][A][U] = 2.000;
+ int22_ar[A][U][A][U][G][A][A][U] = 2.300;
+ int22_ar[A][U][A][U][G][C][A][U] = 1.200;
+ int22_ar[A][U][A][U][G][G][A][U] = 1.900;
+ int22_ar[A][U][A][U][G][U][A][U] = 2.000;
+ int22_ar[A][U][A][U][U][A][A][U] = 2.700;
+ int22_ar[A][U][A][U][U][C][A][U] = 1.500;
+ int22_ar[A][U][A][U][U][G][A][U] = 2.200;
+ int22_ar[A][U][A][U][U][U][A][U] = 2.000;
+ int22_ar[A][U][C][A][A][A][A][U] = 2.500;
+ int22_ar[A][U][C][A][A][C][A][U] = 3.100;
+ int22_ar[A][U][C][A][A][G][A][U] = 2.000;
+ int22_ar[A][U][C][A][A][U][A][U] = 3.100;
+ int22_ar[A][U][C][A][C][A][A][U] = 2.300;
+ int22_ar[A][U][C][A][C][C][A][U] = 2.200;
+ int22_ar[A][U][C][A][C][G][A][U] = 2.000;
+ int22_ar[A][U][C][A][C][U][A][U] = 2.200;
+ int22_ar[A][U][C][A][G][A][A][U] = 1.300;
+ int22_ar[A][U][C][A][G][C][A][U] = 2.200;
+ int22_ar[A][U][C][A][G][G][A][U] = 2.000;
+ int22_ar[A][U][C][A][G][U][A][U] = 2.200;
+ int22_ar[A][U][C][A][U][A][A][U] = 2.000;
+ int22_ar[A][U][C][A][U][C][A][U] = 2.000;
+ int22_ar[A][U][C][A][U][G][A][U] = 2.000;
+ int22_ar[A][U][C][A][U][U][A][U] = 2.000;
+ int22_ar[A][U][C][C][A][A][A][U] = 2.400;
+ int22_ar[A][U][C][C][A][C][A][U] = 2.300;
+ int22_ar[A][U][C][C][A][G][A][U] = 2.000;
+ int22_ar[A][U][C][C][A][U][A][U] = 2.300;
+ int22_ar[A][U][C][C][C][A][A][U] = 2.200;
+ int22_ar[A][U][C][C][C][C][A][U] = 2.200;
+ int22_ar[A][U][C][C][C][G][A][U] = 2.000;
+ int22_ar[A][U][C][C][C][U][A][U] = 2.200;
+ int22_ar[A][U][C][C][G][A][A][U] = 2.000;
+ int22_ar[A][U][C][C][G][C][A][U] = 2.000;
+ int22_ar[A][U][C][C][G][G][A][U] = 2.000;
+ int22_ar[A][U][C][C][G][U][A][U] = 2.000;
+ int22_ar[A][U][C][C][U][A][A][U] = 2.200;
+ int22_ar[A][U][C][C][U][C][A][U] = 2.200;
+ int22_ar[A][U][C][C][U][G][A][U] = 2.000;
+ int22_ar[A][U][C][C][U][U][A][U] = 2.200;
+ int22_ar[A][U][C][G][A][A][A][U] = 1.300;
+ int22_ar[A][U][C][G][A][C][A][U] = 2.200;
+ int22_ar[A][U][C][G][A][G][A][U] = 2.000;
+ int22_ar[A][U][C][G][A][U][A][U] = 2.200;
+ int22_ar[A][U][C][G][C][A][A][U] = 2.000;
+ int22_ar[A][U][C][G][C][C][A][U] = 2.000;
+ int22_ar[A][U][C][G][C][G][A][U] = 2.000;
+ int22_ar[A][U][C][G][C][U][A][U] = 2.000;
+ int22_ar[A][U][C][G][G][A][A][U] = 1.800;
+ int22_ar[A][U][C][G][G][C][A][U] = 2.400;
+ int22_ar[A][U][C][G][G][G][A][U] = 2.000;
+ int22_ar[A][U][C][G][G][U][A][U] = 2.400;
+ int22_ar[A][U][C][G][U][A][A][U] = 0.100;
+ int22_ar[A][U][C][G][U][C][A][U] = 1.000;
+ int22_ar[A][U][C][G][U][G][A][U] = 2.000;
+ int22_ar[A][U][C][G][U][U][A][U] = 1.000;
+ int22_ar[A][U][C][U][A][A][A][U] = 2.000;
+ int22_ar[A][U][C][U][A][C][A][U] = 2.000;
+ int22_ar[A][U][C][U][A][G][A][U] = 2.000;
+ int22_ar[A][U][C][U][A][U][A][U] = 2.000;
+ int22_ar[A][U][C][U][C][A][A][U] = 2.200;
+ int22_ar[A][U][C][U][C][C][A][U] = 2.200;
+ int22_ar[A][U][C][U][C][G][A][U] = 2.000;
+ int22_ar[A][U][C][U][C][U][A][U] = 2.200;
+ int22_ar[A][U][C][U][G][A][A][U] = 1.100;
+ int22_ar[A][U][C][U][G][C][A][U] = 2.000;
+ int22_ar[A][U][C][U][G][G][A][U] = 2.000;
+ int22_ar[A][U][C][U][G][U][A][U] = 2.000;
+ int22_ar[A][U][C][U][U][A][A][U] = 1.400;
+ int22_ar[A][U][C][U][U][C][A][U] = 1.400;
+ int22_ar[A][U][C][U][U][G][A][U] = 2.000;
+ int22_ar[A][U][C][U][U][U][A][U] = 1.400;
+ int22_ar[A][U][G][A][A][A][A][U] = 1.500;
+ int22_ar[A][U][G][A][A][C][A][U] = 2.000;
+ int22_ar[A][U][G][A][A][G][A][U] = 2.100;
+ int22_ar[A][U][G][A][A][U][A][U] = 2.300;
+ int22_ar[A][U][G][A][C][A][A][U] = 1.300;
+ int22_ar[A][U][G][A][C][C][A][U] = 2.000;
+ int22_ar[A][U][G][A][C][G][A][U] = 1.800;
+ int22_ar[A][U][G][A][C][U][A][U] = 1.100;
+ int22_ar[A][U][G][A][G][A][A][U] = 0.300;
+ int22_ar[A][U][G][A][G][C][A][U] = 2.000;
+ int22_ar[A][U][G][A][G][G][A][U] = 0.800;
+ int22_ar[A][U][G][A][G][U][A][U] = 1.900;
+ int22_ar[A][U][G][A][U][A][A][U] = 2.000;
+ int22_ar[A][U][G][A][U][C][A][U] = 2.000;
+ int22_ar[A][U][G][A][U][G][A][U] = 2.000;
+ int22_ar[A][U][G][A][U][U][A][U] = 2.000;
+ int22_ar[A][U][G][C][A][A][A][U] = 1.400;
+ int22_ar[A][U][G][C][A][C][A][U] = 2.000;
+ int22_ar[A][U][G][C][A][G][A][U] = 1.900;
+ int22_ar[A][U][G][C][A][U][A][U] = 1.200;
+ int22_ar[A][U][G][C][C][A][A][U] = 2.200;
+ int22_ar[A][U][G][C][C][C][A][U] = 2.000;
+ int22_ar[A][U][G][C][C][G][A][U] = 2.400;
+ int22_ar[A][U][G][C][C][U][A][U] = 2.000;
+ int22_ar[A][U][G][C][G][A][A][U] = 2.000;
+ int22_ar[A][U][G][C][G][C][A][U] = 2.000;
+ int22_ar[A][U][G][C][G][G][A][U] = 2.000;
+ int22_ar[A][U][G][C][G][U][A][U] = 2.000;
+ int22_ar[A][U][G][C][U][A][A][U] = 2.200;
+ int22_ar[A][U][G][C][U][C][A][U] = 2.000;
+ int22_ar[A][U][G][C][U][G][A][U] = 2.400;
+ int22_ar[A][U][G][C][U][U][A][U] = 2.000;
+ int22_ar[A][U][G][G][A][A][A][U] = 0.300;
+ int22_ar[A][U][G][G][A][C][A][U] = 2.000;
+ int22_ar[A][U][G][G][A][G][A][U] = 0.800;
+ int22_ar[A][U][G][G][A][U][A][U] = 1.900;
+ int22_ar[A][U][G][G][C][A][A][U] = 2.000;
+ int22_ar[A][U][G][G][C][C][A][U] = 2.000;
+ int22_ar[A][U][G][G][C][G][A][U] = 2.000;
+ int22_ar[A][U][G][G][C][U][A][U] = 2.000;
+ int22_ar[A][U][G][G][G][A][A][U] = 0.800;
+ int22_ar[A][U][G][G][G][C][A][U] = 2.000;
+ int22_ar[A][U][G][G][G][G][A][U] = 1.400;
+ int22_ar[A][U][G][G][G][U][A][U] = 1.600;
+ int22_ar[A][U][G][G][U][A][A][U] = 0.900;
+ int22_ar[A][U][G][G][U][C][A][U] = 2.000;
+ int22_ar[A][U][G][G][U][G][A][U] = 0.700;
+ int22_ar[A][U][G][G][U][U][A][U] = -1.100;
+ int22_ar[A][U][G][U][A][A][A][U] = 2.000;
+ int22_ar[A][U][G][U][A][C][A][U] = 2.000;
+ int22_ar[A][U][G][U][A][G][A][U] = 2.000;
+ int22_ar[A][U][G][U][A][U][A][U] = 2.000;
+ int22_ar[A][U][G][U][C][A][A][U] = 2.200;
+ int22_ar[A][U][G][U][C][C][A][U] = 2.000;
+ int22_ar[A][U][G][U][C][G][A][U] = 2.400;
+ int22_ar[A][U][G][U][C][U][A][U] = 2.000;
+ int22_ar[A][U][G][U][G][A][A][U] = 1.900;
+ int22_ar[A][U][G][U][G][C][A][U] = 2.000;
+ int22_ar[A][U][G][U][G][G][A][U] = 1.600;
+ int22_ar[A][U][G][U][G][U][A][U] = -0.100;
+ int22_ar[A][U][G][U][U][A][A][U] = 2.200;
+ int22_ar[A][U][G][U][U][C][A][U] = 2.000;
+ int22_ar[A][U][G][U][U][G][A][U] = 2.000;
+ int22_ar[A][U][G][U][U][U][A][U] = 2.000;
+ int22_ar[A][U][U][A][A][A][A][U] = 2.000;
+ int22_ar[A][U][U][A][A][C][A][U] = 3.100;
+ int22_ar[A][U][U][A][A][G][A][U] = 1.300;
+ int22_ar[A][U][U][A][A][U][A][U] = 2.700;
+ int22_ar[A][U][U][A][C][A][A][U] = 2.000;
+ int22_ar[A][U][U][A][C][C][A][U] = 2.200;
+ int22_ar[A][U][U][A][C][G][A][U] = 0.100;
+ int22_ar[A][U][U][A][C][U][A][U] = 1.400;
+ int22_ar[A][U][U][A][G][A][A][U] = 2.000;
+ int22_ar[A][U][U][A][G][C][A][U] = 2.200;
+ int22_ar[A][U][U][A][G][G][A][U] = 0.900;
+ int22_ar[A][U][U][A][G][U][A][U] = 2.200;
+ int22_ar[A][U][U][A][U][A][A][U] = 2.000;
+ int22_ar[A][U][U][A][U][C][A][U] = 2.000;
+ int22_ar[A][U][U][A][U][G][A][U] = 2.000;
+ int22_ar[A][U][U][A][U][U][A][U] = 2.000;
+ int22_ar[A][U][U][C][A][A][A][U] = 2.000;
+ int22_ar[A][U][U][C][A][C][A][U] = 2.300;
+ int22_ar[A][U][U][C][A][G][A][U] = 0.200;
+ int22_ar[A][U][U][C][A][U][A][U] = 1.500;
+ int22_ar[A][U][U][C][C][A][A][U] = 2.000;
+ int22_ar[A][U][U][C][C][C][A][U] = 2.200;
+ int22_ar[A][U][U][C][C][G][A][U] = 1.000;
+ int22_ar[A][U][U][C][C][U][A][U] = 1.400;
+ int22_ar[A][U][U][C][G][A][A][U] = 2.000;
+ int22_ar[A][U][U][C][G][C][A][U] = 2.000;
+ int22_ar[A][U][U][C][G][G][A][U] = 2.000;
+ int22_ar[A][U][U][C][G][U][A][U] = 2.000;
+ int22_ar[A][U][U][C][U][A][A][U] = 2.000;
+ int22_ar[A][U][U][C][U][C][A][U] = 2.200;
+ int22_ar[A][U][U][C][U][G][A][U] = 1.000;
+ int22_ar[A][U][U][C][U][U][A][U] = 1.400;
+ int22_ar[A][U][U][G][A][A][A][U] = 2.000;
+ int22_ar[A][U][U][G][A][C][A][U] = 2.200;
+ int22_ar[A][U][U][G][A][G][A][U] = 0.900;
+ int22_ar[A][U][U][G][A][U][A][U] = 2.200;
+ int22_ar[A][U][U][G][C][A][A][U] = 2.000;
+ int22_ar[A][U][U][G][C][C][A][U] = 2.000;
+ int22_ar[A][U][U][G][C][G][A][U] = 2.000;
+ int22_ar[A][U][U][G][C][U][A][U] = 2.000;
+ int22_ar[A][U][U][G][G][A][A][U] = 2.000;
+ int22_ar[A][U][U][G][G][C][A][U] = 2.400;
+ int22_ar[A][U][U][G][G][G][A][U] = 0.700;
+ int22_ar[A][U][U][G][G][U][A][U] = 2.000;
+ int22_ar[A][U][U][G][U][A][A][U] = 2.000;
+ int22_ar[A][U][U][G][U][C][A][U] = 1.000;
+ int22_ar[A][U][U][G][U][G][A][U] = -2.100;
+ int22_ar[A][U][U][G][U][U][A][U] = 1.100;
+ int22_ar[A][U][U][U][A][A][A][U] = 2.000;
+ int22_ar[A][U][U][U][A][C][A][U] = 2.000;
+ int22_ar[A][U][U][U][A][G][A][U] = 2.000;
+ int22_ar[A][U][U][U][A][U][A][U] = 2.000;
+ int22_ar[A][U][U][U][C][A][A][U] = 2.000;
+ int22_ar[A][U][U][U][C][C][A][U] = 2.200;
+ int22_ar[A][U][U][U][C][G][A][U] = 1.000;
+ int22_ar[A][U][U][U][C][U][A][U] = 1.400;
+ int22_ar[A][U][U][U][G][A][A][U] = 2.000;
+ int22_ar[A][U][U][U][G][C][A][U] = 2.000;
+ int22_ar[A][U][U][U][G][G][A][U] = -1.100;
+ int22_ar[A][U][U][U][G][U][A][U] = 2.000;
+ int22_ar[A][U][U][U][U][A][A][U] = 2.000;
+ int22_ar[A][U][U][U][U][C][A][U] = 1.400;
+ int22_ar[A][U][U][U][U][G][A][U] = 1.100;
+ int22_ar[A][U][U][U][U][U][A][U] = 0.600;
+ int22_ar[A][U][A][A][A][A][C][G] = 2.000;
+ int22_ar[A][U][A][A][A][C][C][G] = 1.900;
+ int22_ar[A][U][A][A][A][G][C][G] = 0.800;
+ int22_ar[A][U][A][A][A][U][C][G] = 2.000;
+ int22_ar[A][U][A][A][C][A][C][G] = 1.900;
+ int22_ar[A][U][A][A][C][C][C][G] = 1.800;
+ int22_ar[A][U][A][A][C][G][C][G] = 0.700;
+ int22_ar[A][U][A][A][C][U][C][G] = 2.000;
+ int22_ar[A][U][A][A][G][A][C][G] = 1.000;
+ int22_ar[A][U][A][A][G][C][C][G] = 0.900;
+ int22_ar[A][U][A][A][G][G][C][G] = -0.200;
+ int22_ar[A][U][A][A][G][U][C][G] = 2.000;
+ int22_ar[A][U][A][A][U][A][C][G] = 2.000;
+ int22_ar[A][U][A][A][U][C][C][G] = 2.000;
+ int22_ar[A][U][A][A][U][G][C][G] = 2.000;
+ int22_ar[A][U][A][A][U][U][C][G] = 2.000;
+ int22_ar[A][U][A][C][A][A][C][G] = 2.400;
+ int22_ar[A][U][A][C][A][C][C][G] = 2.200;
+ int22_ar[A][U][A][C][A][G][C][G] = 1.100;
+ int22_ar[A][U][A][C][A][U][C][G] = 2.000;
+ int22_ar[A][U][A][C][C][A][C][G] = 2.800;
+ int22_ar[A][U][A][C][C][C][C][G] = 2.100;
+ int22_ar[A][U][A][C][C][G][C][G] = 2.000;
+ int22_ar[A][U][A][C][C][U][C][G] = 2.000;
+ int22_ar[A][U][A][C][G][A][C][G] = 2.000;
+ int22_ar[A][U][A][C][G][C][C][G] = 2.000;
+ int22_ar[A][U][A][C][G][G][C][G] = 2.000;
+ int22_ar[A][U][A][C][G][U][C][G] = 2.000;
+ int22_ar[A][U][A][C][U][A][C][G] = 2.700;
+ int22_ar[A][U][A][C][U][C][C][G] = 1.900;
+ int22_ar[A][U][A][C][U][G][C][G] = 1.800;
+ int22_ar[A][U][A][C][U][U][C][G] = 2.000;
+ int22_ar[A][U][A][G][A][A][C][G] = 1.000;
+ int22_ar[A][U][A][G][A][C][C][G] = 0.900;
+ int22_ar[A][U][A][G][A][G][C][G] = -0.200;
+ int22_ar[A][U][A][G][A][U][C][G] = 2.000;
+ int22_ar[A][U][A][G][C][A][C][G] = 2.000;
+ int22_ar[A][U][A][G][C][C][C][G] = 2.000;
+ int22_ar[A][U][A][G][C][G][C][G] = 2.000;
+ int22_ar[A][U][A][G][C][U][C][G] = 2.000;
+ int22_ar[A][U][A][G][G][A][C][G] = 1.800;
+ int22_ar[A][U][A][G][G][C][C][G] = 1.600;
+ int22_ar[A][U][A][G][G][G][C][G] = 0.500;
+ int22_ar[A][U][A][G][G][U][C][G] = 2.000;
+ int22_ar[A][U][A][G][U][A][C][G] = 0.300;
+ int22_ar[A][U][A][G][U][C][C][G] = -0.800;
+ int22_ar[A][U][A][G][U][G][C][G] = -0.100;
+ int22_ar[A][U][A][G][U][U][C][G] = 2.000;
+ int22_ar[A][U][A][U][A][A][C][G] = 2.000;
+ int22_ar[A][U][A][U][A][C][C][G] = 2.000;
+ int22_ar[A][U][A][U][A][G][C][G] = 2.000;
+ int22_ar[A][U][A][U][A][U][C][G] = 2.000;
+ int22_ar[A][U][A][U][C][A][C][G] = 2.700;
+ int22_ar[A][U][A][U][C][C][C][G] = 1.900;
+ int22_ar[A][U][A][U][C][G][C][G] = 1.800;
+ int22_ar[A][U][A][U][C][U][C][G] = 2.000;
+ int22_ar[A][U][A][U][G][A][C][G] = 1.800;
+ int22_ar[A][U][A][U][G][C][C][G] = 0.700;
+ int22_ar[A][U][A][U][G][G][C][G] = 1.400;
+ int22_ar[A][U][A][U][G][U][C][G] = 2.000;
+ int22_ar[A][U][A][U][U][A][C][G] = 2.200;
+ int22_ar[A][U][A][U][U][C][C][G] = 1.000;
+ int22_ar[A][U][A][U][U][G][C][G] = 1.800;
+ int22_ar[A][U][A][U][U][U][C][G] = 2.000;
+ int22_ar[A][U][C][A][A][A][C][G] = 1.800;
+ int22_ar[A][U][C][A][A][C][C][G] = 2.300;
+ int22_ar[A][U][C][A][A][G][C][G] = 2.000;
+ int22_ar[A][U][C][A][A][U][C][G] = 2.300;
+ int22_ar[A][U][C][A][C][A][C][G] = 1.700;
+ int22_ar[A][U][C][A][C][C][C][G] = 1.600;
+ int22_ar[A][U][C][A][C][G][C][G] = 2.000;
+ int22_ar[A][U][C][A][C][U][C][G] = 1.600;
+ int22_ar[A][U][C][A][G][A][C][G] = 0.800;
+ int22_ar[A][U][C][A][G][C][C][G] = 1.700;
+ int22_ar[A][U][C][A][G][G][C][G] = 2.000;
+ int22_ar[A][U][C][A][G][U][C][G] = 1.700;
+ int22_ar[A][U][C][A][U][A][C][G] = 2.000;
+ int22_ar[A][U][C][A][U][C][C][G] = 2.000;
+ int22_ar[A][U][C][A][U][G][C][G] = 2.000;
+ int22_ar[A][U][C][A][U][U][C][G] = 2.000;
+ int22_ar[A][U][C][C][A][A][C][G] = 2.100;
+ int22_ar[A][U][C][C][A][C][C][G] = 2.100;
+ int22_ar[A][U][C][C][A][G][C][G] = 2.000;
+ int22_ar[A][U][C][C][A][U][C][G] = 2.100;
+ int22_ar[A][U][C][C][C][A][C][G] = 2.000;
+ int22_ar[A][U][C][C][C][C][C][G] = 1.900;
+ int22_ar[A][U][C][C][C][G][C][G] = 2.000;
+ int22_ar[A][U][C][C][C][U][C][G] = 1.900;
+ int22_ar[A][U][C][C][G][A][C][G] = 2.000;
+ int22_ar[A][U][C][C][G][C][C][G] = 2.000;
+ int22_ar[A][U][C][C][G][G][C][G] = 2.000;
+ int22_ar[A][U][C][C][G][U][C][G] = 2.000;
+ int22_ar[A][U][C][C][U][A][C][G] = 1.800;
+ int22_ar[A][U][C][C][U][C][C][G] = 1.800;
+ int22_ar[A][U][C][C][U][G][C][G] = 2.000;
+ int22_ar[A][U][C][C][U][U][C][G] = 1.800;
+ int22_ar[A][U][C][G][A][A][C][G] = 0.800;
+ int22_ar[A][U][C][G][A][C][C][G] = 1.700;
+ int22_ar[A][U][C][G][A][G][C][G] = 2.000;
+ int22_ar[A][U][C][G][A][U][C][G] = 1.700;
+ int22_ar[A][U][C][G][C][A][C][G] = 2.000;
+ int22_ar[A][U][C][G][C][C][C][G] = 2.000;
+ int22_ar[A][U][C][G][C][G][C][G] = 2.000;
+ int22_ar[A][U][C][G][C][U][C][G] = 2.000;
+ int22_ar[A][U][C][G][G][A][C][G] = 1.500;
+ int22_ar[A][U][C][G][G][C][C][G] = 2.100;
+ int22_ar[A][U][C][G][G][G][C][G] = 2.000;
+ int22_ar[A][U][C][G][G][U][C][G] = 2.100;
+ int22_ar[A][U][C][G][U][A][C][G] = -0.900;
+ int22_ar[A][U][C][G][U][C][C][G] = 0.000;
+ int22_ar[A][U][C][G][U][G][C][G] = 2.000;
+ int22_ar[A][U][C][G][U][U][C][G] = 0.000;
+ int22_ar[A][U][C][U][A][A][C][G] = 2.000;
+ int22_ar[A][U][C][U][A][C][C][G] = 2.000;
+ int22_ar[A][U][C][U][A][G][C][G] = 2.000;
+ int22_ar[A][U][C][U][A][U][C][G] = 2.000;
+ int22_ar[A][U][C][U][C][A][C][G] = 1.800;
+ int22_ar[A][U][C][U][C][C][C][G] = 1.800;
+ int22_ar[A][U][C][U][C][G][C][G] = 2.000;
+ int22_ar[A][U][C][U][C][U][C][G] = 1.800;
+ int22_ar[A][U][C][U][G][A][C][G] = 0.600;
+ int22_ar[A][U][C][U][G][C][C][G] = 1.500;
+ int22_ar[A][U][C][U][G][G][C][G] = 2.000;
+ int22_ar[A][U][C][U][G][U][C][G] = 1.500;
+ int22_ar[A][U][C][U][U][A][C][G] = 0.900;
+ int22_ar[A][U][C][U][U][C][C][G] = 0.900;
+ int22_ar[A][U][C][U][U][G][C][G] = 2.000;
+ int22_ar[A][U][C][U][U][U][C][G] = 0.900;
+ int22_ar[A][U][G][A][A][A][C][G] = 0.800;
+ int22_ar[A][U][G][A][A][C][C][G] = 2.000;
+ int22_ar[A][U][G][A][A][G][C][G] = 1.300;
+ int22_ar[A][U][G][A][A][U][C][G] = 1.600;
+ int22_ar[A][U][G][A][C][A][C][G] = 0.700;
+ int22_ar[A][U][G][A][C][C][C][G] = 2.000;
+ int22_ar[A][U][G][A][C][G][C][G] = 1.200;
+ int22_ar[A][U][G][A][C][U][C][G] = 0.500;
+ int22_ar[A][U][G][A][G][A][C][G] = -0.200;
+ int22_ar[A][U][G][A][G][C][C][G] = 2.000;
+ int22_ar[A][U][G][A][G][G][C][G] = 0.300;
+ int22_ar[A][U][G][A][G][U][C][G] = 1.400;
+ int22_ar[A][U][G][A][U][A][C][G] = 2.000;
+ int22_ar[A][U][G][A][U][C][C][G] = 2.000;
+ int22_ar[A][U][G][A][U][G][C][G] = 2.000;
+ int22_ar[A][U][G][A][U][U][C][G] = 2.000;
+ int22_ar[A][U][G][C][A][A][C][G] = 1.100;
+ int22_ar[A][U][G][C][A][C][C][G] = 2.000;
+ int22_ar[A][U][G][C][A][G][C][G] = 1.700;
+ int22_ar[A][U][G][C][A][U][C][G] = 0.900;
+ int22_ar[A][U][G][C][C][A][C][G] = 2.000;
+ int22_ar[A][U][G][C][C][C][C][G] = 2.000;
+ int22_ar[A][U][G][C][C][G][C][G] = 2.100;
+ int22_ar[A][U][G][C][C][U][C][G] = 1.800;
+ int22_ar[A][U][G][C][G][A][C][G] = 2.000;
+ int22_ar[A][U][G][C][G][C][C][G] = 2.000;
+ int22_ar[A][U][G][C][G][G][C][G] = 2.000;
+ int22_ar[A][U][G][C][G][U][C][G] = 2.000;
+ int22_ar[A][U][G][C][U][A][C][G] = 1.800;
+ int22_ar[A][U][G][C][U][C][C][G] = 2.000;
+ int22_ar[A][U][G][C][U][G][C][G] = 2.000;
+ int22_ar[A][U][G][C][U][U][C][G] = 1.600;
+ int22_ar[A][U][G][G][A][A][C][G] = -0.200;
+ int22_ar[A][U][G][G][A][C][C][G] = 2.000;
+ int22_ar[A][U][G][G][A][G][C][G] = 0.300;
+ int22_ar[A][U][G][G][A][U][C][G] = 1.400;
+ int22_ar[A][U][G][G][C][A][C][G] = 2.000;
+ int22_ar[A][U][G][G][C][C][C][G] = 2.000;
+ int22_ar[A][U][G][G][C][G][C][G] = 2.000;
+ int22_ar[A][U][G][G][C][U][C][G] = 2.000;
+ int22_ar[A][U][G][G][G][A][C][G] = 0.500;
+ int22_ar[A][U][G][G][G][C][C][G] = 2.000;
+ int22_ar[A][U][G][G][G][G][C][G] = 1.100;
+ int22_ar[A][U][G][G][G][U][C][G] = 1.300;
+ int22_ar[A][U][G][G][U][A][C][G] = -0.100;
+ int22_ar[A][U][G][G][U][C][C][G] = 2.000;
+ int22_ar[A][U][G][G][U][G][C][G] = -0.400;
+ int22_ar[A][U][G][G][U][U][C][G] = -2.100;
+ int22_ar[A][U][G][U][A][A][C][G] = 2.000;
+ int22_ar[A][U][G][U][A][C][C][G] = 2.000;
+ int22_ar[A][U][G][U][A][G][C][G] = 2.000;
+ int22_ar[A][U][G][U][A][U][C][G] = 2.000;
+ int22_ar[A][U][G][U][C][A][C][G] = 1.800;
+ int22_ar[A][U][G][U][C][C][C][G] = 2.000;
+ int22_ar[A][U][G][U][C][G][C][G] = 2.000;
+ int22_ar[A][U][G][U][C][U][C][G] = 1.600;
+ int22_ar[A][U][G][U][G][A][C][G] = 1.400;
+ int22_ar[A][U][G][U][G][C][C][G] = 2.000;
+ int22_ar[A][U][G][U][G][G][C][G] = 1.100;
+ int22_ar[A][U][G][U][G][U][C][G] = -0.600;
+ int22_ar[A][U][G][U][U][A][C][G] = 1.800;
+ int22_ar[A][U][G][U][U][C][C][G] = 2.000;
+ int22_ar[A][U][G][U][U][G][C][G] = 1.500;
+ int22_ar[A][U][G][U][U][U][C][G] = 1.600;
+ int22_ar[A][U][U][A][A][A][C][G] = 2.000;
+ int22_ar[A][U][U][A][A][C][C][G] = 2.300;
+ int22_ar[A][U][U][A][A][G][C][G] = 0.600;
+ int22_ar[A][U][U][A][A][U][C][G] = 1.900;
+ int22_ar[A][U][U][A][C][A][C][G] = 2.000;
+ int22_ar[A][U][U][A][C][C][C][G] = 1.600;
+ int22_ar[A][U][U][A][C][G][C][G] = -0.500;
+ int22_ar[A][U][U][A][C][U][C][G] = 0.800;
+ int22_ar[A][U][U][A][G][A][C][G] = 2.000;
+ int22_ar[A][U][U][A][G][C][C][G] = 1.700;
+ int22_ar[A][U][U][A][G][G][C][G] = 0.400;
+ int22_ar[A][U][U][A][G][U][C][G] = 1.800;
+ int22_ar[A][U][U][A][U][A][C][G] = 2.000;
+ int22_ar[A][U][U][A][U][C][C][G] = 2.000;
+ int22_ar[A][U][U][A][U][G][C][G] = 2.000;
+ int22_ar[A][U][U][A][U][U][C][G] = 2.000;
+ int22_ar[A][U][U][C][A][A][C][G] = 2.000;
+ int22_ar[A][U][U][C][A][C][C][G] = 2.100;
+ int22_ar[A][U][U][C][A][G][C][G] = 0.000;
+ int22_ar[A][U][U][C][A][U][C][G] = 1.300;
+ int22_ar[A][U][U][C][C][A][C][G] = 2.000;
+ int22_ar[A][U][U][C][C][C][C][G] = 1.900;
+ int22_ar[A][U][U][C][C][G][C][G] = 0.800;
+ int22_ar[A][U][U][C][C][U][C][G] = 1.100;
+ int22_ar[A][U][U][C][G][A][C][G] = 2.000;
+ int22_ar[A][U][U][C][G][C][C][G] = 2.000;
+ int22_ar[A][U][U][C][G][G][C][G] = 2.000;
+ int22_ar[A][U][U][C][G][U][C][G] = 2.000;
+ int22_ar[A][U][U][C][U][A][C][G] = 2.000;
+ int22_ar[A][U][U][C][U][C][C][G] = 1.800;
+ int22_ar[A][U][U][C][U][G][C][G] = 0.700;
+ int22_ar[A][U][U][C][U][U][C][G] = 1.000;
+ int22_ar[A][U][U][G][A][A][C][G] = 2.000;
+ int22_ar[A][U][U][G][A][C][C][G] = 1.700;
+ int22_ar[A][U][U][G][A][G][C][G] = 0.400;
+ int22_ar[A][U][U][G][A][U][C][G] = 1.800;
+ int22_ar[A][U][U][G][C][A][C][G] = 2.000;
+ int22_ar[A][U][U][G][C][C][C][G] = 2.000;
+ int22_ar[A][U][U][G][C][G][C][G] = 2.000;
+ int22_ar[A][U][U][G][C][U][C][G] = 2.000;
+ int22_ar[A][U][U][G][G][A][C][G] = 2.000;
+ int22_ar[A][U][U][G][G][C][C][G] = 2.100;
+ int22_ar[A][U][U][G][G][G][C][G] = 0.400;
+ int22_ar[A][U][U][G][G][U][C][G] = 1.700;
+ int22_ar[A][U][U][G][U][A][C][G] = 2.000;
+ int22_ar[A][U][U][G][U][C][C][G] = 0.000;
+ int22_ar[A][U][U][G][U][G][C][G] = -3.100;
+ int22_ar[A][U][U][G][U][U][C][G] = 0.000;
+ int22_ar[A][U][U][U][A][A][C][G] = 2.000;
+ int22_ar[A][U][U][U][A][C][C][G] = 2.000;
+ int22_ar[A][U][U][U][A][G][C][G] = 2.000;
+ int22_ar[A][U][U][U][A][U][C][G] = 2.000;
+ int22_ar[A][U][U][U][C][A][C][G] = 2.000;
+ int22_ar[A][U][U][U][C][C][C][G] = 1.800;
+ int22_ar[A][U][U][U][C][G][C][G] = 0.700;
+ int22_ar[A][U][U][U][C][U][C][G] = 1.000;
+ int22_ar[A][U][U][U][G][A][C][G] = 2.000;
+ int22_ar[A][U][U][U][G][C][C][G] = 1.500;
+ int22_ar[A][U][U][U][G][G][C][G] = -1.600;
+ int22_ar[A][U][U][U][G][U][C][G] = 1.600;
+ int22_ar[A][U][U][U][U][A][C][G] = 2.000;
+ int22_ar[A][U][U][U][U][C][C][G] = 0.900;
+ int22_ar[A][U][U][U][U][G][C][G] = 0.600;
+ int22_ar[A][U][U][U][U][U][C][G] = 0.100;
+ int22_ar[A][U][A][A][A][A][G][C] = 2.100;
+ int22_ar[A][U][A][A][A][C][G][C] = 2.000;
+ int22_ar[A][U][A][A][A][G][G][C] = 0.900;
+ int22_ar[A][U][A][A][A][U][G][C] = 2.000;
+ int22_ar[A][U][A][A][C][A][G][C] = 1.900;
+ int22_ar[A][U][A][A][C][C][G][C] = 1.700;
+ int22_ar[A][U][A][A][C][G][G][C] = 0.600;
+ int22_ar[A][U][A][A][C][U][G][C] = 2.000;
+ int22_ar[A][U][A][A][G][A][G][C] = 0.100;
+ int22_ar[A][U][A][A][G][C][G][C] = 0.000;
+ int22_ar[A][U][A][A][G][G][G][C] = -1.100;
+ int22_ar[A][U][A][A][G][U][G][C] = 2.000;
+ int22_ar[A][U][A][A][U][A][G][C] = 2.000;
+ int22_ar[A][U][A][A][U][C][G][C] = 2.000;
+ int22_ar[A][U][A][A][U][G][G][C] = 2.000;
+ int22_ar[A][U][A][A][U][U][G][C] = 2.000;
+ int22_ar[A][U][A][C][A][A][G][C] = 1.800;
+ int22_ar[A][U][A][C][A][C][G][C] = 1.700;
+ int22_ar[A][U][A][C][A][G][G][C] = 0.600;
+ int22_ar[A][U][A][C][A][U][G][C] = 2.000;
+ int22_ar[A][U][A][C][C][A][G][C] = 2.500;
+ int22_ar[A][U][A][C][C][C][G][C] = 1.700;
+ int22_ar[A][U][A][C][C][G][G][C] = 1.600;
+ int22_ar[A][U][A][C][C][U][G][C] = 2.000;
+ int22_ar[A][U][A][C][G][A][G][C] = 2.000;
+ int22_ar[A][U][A][C][G][C][G][C] = 2.000;
+ int22_ar[A][U][A][C][G][G][G][C] = 2.000;
+ int22_ar[A][U][A][C][G][U][G][C] = 2.000;
+ int22_ar[A][U][A][C][U][A][G][C] = 1.500;
+ int22_ar[A][U][A][C][U][C][G][C] = 0.700;
+ int22_ar[A][U][A][C][U][G][G][C] = 0.700;
+ int22_ar[A][U][A][C][U][U][G][C] = 2.000;
+ int22_ar[A][U][A][G][A][A][G][C] = 0.700;
+ int22_ar[A][U][A][G][A][C][G][C] = 0.600;
+ int22_ar[A][U][A][G][A][G][G][C] = -0.500;
+ int22_ar[A][U][A][G][A][U][G][C] = 2.000;
+ int22_ar[A][U][A][G][C][A][G][C] = 2.000;
+ int22_ar[A][U][A][G][C][C][G][C] = 2.000;
+ int22_ar[A][U][A][G][C][G][G][C] = 2.000;
+ int22_ar[A][U][A][G][C][U][G][C] = 2.000;
+ int22_ar[A][U][A][G][G][A][G][C] = 1.800;
+ int22_ar[A][U][A][G][G][C][G][C] = 1.600;
+ int22_ar[A][U][A][G][G][G][G][C] = 0.500;
+ int22_ar[A][U][A][G][G][U][G][C] = 2.000;
+ int22_ar[A][U][A][G][U][A][G][C] = 0.000;
+ int22_ar[A][U][A][G][U][C][G][C] = -1.200;
+ int22_ar[A][U][A][G][U][G][G][C] = -0.500;
+ int22_ar[A][U][A][G][U][U][G][C] = 2.000;
+ int22_ar[A][U][A][U][A][A][G][C] = 2.000;
+ int22_ar[A][U][A][U][A][C][G][C] = 2.000;
+ int22_ar[A][U][A][U][A][G][G][C] = 2.000;
+ int22_ar[A][U][A][U][A][U][G][C] = 2.000;
+ int22_ar[A][U][A][U][C][A][G][C] = 2.500;
+ int22_ar[A][U][A][U][C][C][G][C] = 1.800;
+ int22_ar[A][U][A][U][C][G][G][C] = 1.700;
+ int22_ar[A][U][A][U][C][U][G][C] = 2.000;
+ int22_ar[A][U][A][U][G][A][G][C] = 0.400;
+ int22_ar[A][U][A][U][G][C][G][C] = -0.800;
+ int22_ar[A][U][A][U][G][G][G][C] = -0.100;
+ int22_ar[A][U][A][U][G][U][G][C] = 2.000;
+ int22_ar[A][U][A][U][U][A][G][C] = 2.100;
+ int22_ar[A][U][A][U][U][C][G][C] = 1.000;
+ int22_ar[A][U][A][U][U][G][G][C] = 1.700;
+ int22_ar[A][U][A][U][U][U][G][C] = 2.000;
+ int22_ar[A][U][C][A][A][A][G][C] = 1.900;
+ int22_ar[A][U][C][A][A][C][G][C] = 2.400;
+ int22_ar[A][U][C][A][A][G][G][C] = 2.000;
+ int22_ar[A][U][C][A][A][U][G][C] = 2.400;
+ int22_ar[A][U][C][A][C][A][G][C] = 1.600;
+ int22_ar[A][U][C][A][C][C][G][C] = 1.600;
+ int22_ar[A][U][C][A][C][G][G][C] = 2.000;
+ int22_ar[A][U][C][A][C][U][G][C] = 1.600;
+ int22_ar[A][U][C][A][G][A][G][C] = -0.100;
+ int22_ar[A][U][C][A][G][C][G][C] = 0.800;
+ int22_ar[A][U][C][A][G][G][G][C] = 2.000;
+ int22_ar[A][U][C][A][G][U][G][C] = 0.800;
+ int22_ar[A][U][C][A][U][A][G][C] = 2.000;
+ int22_ar[A][U][C][A][U][C][G][C] = 2.000;
+ int22_ar[A][U][C][A][U][G][G][C] = 2.000;
+ int22_ar[A][U][C][A][U][U][G][C] = 2.000;
+ int22_ar[A][U][C][C][A][A][G][C] = 1.600;
+ int22_ar[A][U][C][C][A][C][G][C] = 1.500;
+ int22_ar[A][U][C][C][A][G][G][C] = 2.000;
+ int22_ar[A][U][C][C][A][U][G][C] = 1.500;
+ int22_ar[A][U][C][C][C][A][G][C] = 1.600;
+ int22_ar[A][U][C][C][C][C][G][C] = 1.600;
+ int22_ar[A][U][C][C][C][G][G][C] = 2.000;
+ int22_ar[A][U][C][C][C][U][G][C] = 1.600;
+ int22_ar[A][U][C][C][G][A][G][C] = 2.000;
+ int22_ar[A][U][C][C][G][C][G][C] = 2.000;
+ int22_ar[A][U][C][C][G][G][G][C] = 2.000;
+ int22_ar[A][U][C][C][G][U][G][C] = 2.000;
+ int22_ar[A][U][C][C][U][A][G][C] = 0.600;
+ int22_ar[A][U][C][C][U][C][G][C] = 0.600;
+ int22_ar[A][U][C][C][U][G][G][C] = 2.000;
+ int22_ar[A][U][C][C][U][U][G][C] = 0.600;
+ int22_ar[A][U][C][G][A][A][G][C] = 0.500;
+ int22_ar[A][U][C][G][A][C][G][C] = 1.400;
+ int22_ar[A][U][C][G][A][G][G][C] = 2.000;
+ int22_ar[A][U][C][G][A][U][G][C] = 1.400;
+ int22_ar[A][U][C][G][C][A][G][C] = 2.000;
+ int22_ar[A][U][C][G][C][C][G][C] = 2.000;
+ int22_ar[A][U][C][G][C][G][G][C] = 2.000;
+ int22_ar[A][U][C][G][C][U][G][C] = 2.000;
+ int22_ar[A][U][C][G][G][A][G][C] = 1.500;
+ int22_ar[A][U][C][G][G][C][G][C] = 2.100;
+ int22_ar[A][U][C][G][G][G][G][C] = 2.000;
+ int22_ar[A][U][C][G][G][U][G][C] = 2.100;
+ int22_ar[A][U][C][G][U][A][G][C] = -1.300;
+ int22_ar[A][U][C][G][U][C][G][C] = -0.300;
+ int22_ar[A][U][C][G][U][G][G][C] = 2.000;
+ int22_ar[A][U][C][G][U][U][G][C] = -0.300;
+ int22_ar[A][U][C][U][A][A][G][C] = 2.000;
+ int22_ar[A][U][C][U][A][C][G][C] = 2.000;
+ int22_ar[A][U][C][U][A][G][G][C] = 2.000;
+ int22_ar[A][U][C][U][A][U][G][C] = 2.000;
+ int22_ar[A][U][C][U][C][A][G][C] = 1.700;
+ int22_ar[A][U][C][U][C][C][G][C] = 1.600;
+ int22_ar[A][U][C][U][C][G][G][C] = 2.000;
+ int22_ar[A][U][C][U][C][U][G][C] = 1.600;
+ int22_ar[A][U][C][U][G][A][G][C] = -0.900;
+ int22_ar[A][U][C][U][G][C][G][C] = 0.100;
+ int22_ar[A][U][C][U][G][G][G][C] = 2.000;
+ int22_ar[A][U][C][U][G][U][G][C] = 0.100;
+ int22_ar[A][U][C][U][U][A][G][C] = 0.900;
+ int22_ar[A][U][C][U][U][C][G][C] = 0.800;
+ int22_ar[A][U][C][U][U][G][G][C] = 2.000;
+ int22_ar[A][U][C][U][U][U][G][C] = 0.800;
+ int22_ar[A][U][G][A][A][A][G][C] = 0.900;
+ int22_ar[A][U][G][A][A][C][G][C] = 2.000;
+ int22_ar[A][U][G][A][A][G][G][C] = 1.400;
+ int22_ar[A][U][G][A][A][U][G][C] = 1.700;
+ int22_ar[A][U][G][A][C][A][G][C] = 0.600;
+ int22_ar[A][U][G][A][C][C][G][C] = 2.000;
+ int22_ar[A][U][G][A][C][G][G][C] = 1.200;
+ int22_ar[A][U][G][A][C][U][G][C] = 0.400;
+ int22_ar[A][U][G][A][G][A][G][C] = -1.100;
+ int22_ar[A][U][G][A][G][C][G][C] = 2.000;
+ int22_ar[A][U][G][A][G][G][G][C] = -0.600;
+ int22_ar[A][U][G][A][G][U][G][C] = 0.500;
+ int22_ar[A][U][G][A][U][A][G][C] = 2.000;
+ int22_ar[A][U][G][A][U][C][G][C] = 2.000;
+ int22_ar[A][U][G][A][U][G][G][C] = 2.000;
+ int22_ar[A][U][G][A][U][U][G][C] = 2.000;
+ int22_ar[A][U][G][C][A][A][G][C] = 0.600;
+ int22_ar[A][U][G][C][A][C][G][C] = 2.000;
+ int22_ar[A][U][G][C][A][G][G][C] = 1.100;
+ int22_ar[A][U][G][C][A][U][G][C] = 0.400;
+ int22_ar[A][U][G][C][C][A][G][C] = 1.600;
+ int22_ar[A][U][G][C][C][C][G][C] = 2.000;
+ int22_ar[A][U][G][C][C][G][G][C] = 1.800;
+ int22_ar[A][U][G][C][C][U][G][C] = 1.400;
+ int22_ar[A][U][G][C][G][A][G][C] = 2.000;
+ int22_ar[A][U][G][C][G][C][G][C] = 2.000;
+ int22_ar[A][U][G][C][G][G][G][C] = 2.000;
+ int22_ar[A][U][G][C][G][U][G][C] = 2.000;
+ int22_ar[A][U][G][C][U][A][G][C] = 0.700;
+ int22_ar[A][U][G][C][U][C][G][C] = 2.000;
+ int22_ar[A][U][G][C][U][G][G][C] = 0.800;
+ int22_ar[A][U][G][C][U][U][G][C] = 0.500;
+ int22_ar[A][U][G][G][A][A][G][C] = -0.500;
+ int22_ar[A][U][G][G][A][C][G][C] = 2.000;
+ int22_ar[A][U][G][G][A][G][G][C] = 0.000;
+ int22_ar[A][U][G][G][A][U][G][C] = 1.100;
+ int22_ar[A][U][G][G][C][A][G][C] = 2.000;
+ int22_ar[A][U][G][G][C][C][G][C] = 2.000;
+ int22_ar[A][U][G][G][C][G][G][C] = 2.000;
+ int22_ar[A][U][G][G][C][U][G][C] = 2.000;
+ int22_ar[A][U][G][G][G][A][G][C] = 0.500;
+ int22_ar[A][U][G][G][G][C][G][C] = 2.000;
+ int22_ar[A][U][G][G][G][G][G][C] = 1.100;
+ int22_ar[A][U][G][G][G][U][G][C] = 1.300;
+ int22_ar[A][U][G][G][U][A][G][C] = -0.500;
+ int22_ar[A][U][G][G][U][C][G][C] = 2.000;
+ int22_ar[A][U][G][G][U][G][G][C] = -0.700;
+ int22_ar[A][U][G][G][U][U][G][C] = -2.500;
+ int22_ar[A][U][G][U][A][A][G][C] = 2.000;
+ int22_ar[A][U][G][U][A][C][G][C] = 2.000;
+ int22_ar[A][U][G][U][A][G][G][C] = 2.000;
+ int22_ar[A][U][G][U][A][U][G][C] = 2.000;
+ int22_ar[A][U][G][U][C][A][G][C] = 1.700;
+ int22_ar[A][U][G][U][C][C][G][C] = 2.000;
+ int22_ar[A][U][G][U][C][G][G][C] = 1.800;
+ int22_ar[A][U][G][U][C][U][G][C] = 1.500;
+ int22_ar[A][U][G][U][G][A][G][C] = -0.100;
+ int22_ar[A][U][G][U][G][C][G][C] = 2.000;
+ int22_ar[A][U][G][U][G][G][G][C] = -0.300;
+ int22_ar[A][U][G][U][G][U][G][C] = -2.100;
+ int22_ar[A][U][G][U][U][A][G][C] = 1.700;
+ int22_ar[A][U][G][U][U][C][G][C] = 2.000;
+ int22_ar[A][U][G][U][U][G][G][C] = 1.400;
+ int22_ar[A][U][G][U][U][U][G][C] = 1.500;
+ int22_ar[A][U][U][A][A][A][G][C] = 2.000;
+ int22_ar[A][U][U][A][A][C][G][C] = 2.400;
+ int22_ar[A][U][U][A][A][G][G][C] = 0.700;
+ int22_ar[A][U][U][A][A][U][G][C] = 2.000;
+ int22_ar[A][U][U][A][C][A][G][C] = 2.000;
+ int22_ar[A][U][U][A][C][C][G][C] = 1.600;
+ int22_ar[A][U][U][A][C][G][G][C] = -0.500;
+ int22_ar[A][U][U][A][C][U][G][C] = 0.800;
+ int22_ar[A][U][U][A][G][A][G][C] = 2.000;
+ int22_ar[A][U][U][A][G][C][G][C] = 0.800;
+ int22_ar[A][U][U][A][G][G][G][C] = -0.500;
+ int22_ar[A][U][U][A][G][U][G][C] = 0.800;
+ int22_ar[A][U][U][A][U][A][G][C] = 2.000;
+ int22_ar[A][U][U][A][U][C][G][C] = 2.000;
+ int22_ar[A][U][U][A][U][G][G][C] = 2.000;
+ int22_ar[A][U][U][A][U][U][G][C] = 2.000;
+ int22_ar[A][U][U][C][A][A][G][C] = 2.000;
+ int22_ar[A][U][U][C][A][C][G][C] = 1.500;
+ int22_ar[A][U][U][C][A][G][G][C] = -0.600;
+ int22_ar[A][U][U][C][A][U][G][C] = 0.700;
+ int22_ar[A][U][U][C][C][A][G][C] = 2.000;
+ int22_ar[A][U][U][C][C][C][G][C] = 1.600;
+ int22_ar[A][U][U][C][C][G][G][C] = 0.500;
+ int22_ar[A][U][U][C][C][U][G][C] = 0.800;
+ int22_ar[A][U][U][C][G][A][G][C] = 2.000;
+ int22_ar[A][U][U][C][G][C][G][C] = 2.000;
+ int22_ar[A][U][U][C][G][G][G][C] = 2.000;
+ int22_ar[A][U][U][C][G][U][G][C] = 2.000;
+ int22_ar[A][U][U][C][U][A][G][C] = 2.000;
+ int22_ar[A][U][U][C][U][C][G][C] = 0.600;
+ int22_ar[A][U][U][C][U][G][G][C] = -0.500;
+ int22_ar[A][U][U][C][U][U][G][C] = -0.200;
+ int22_ar[A][U][U][G][A][A][G][C] = 2.000;
+ int22_ar[A][U][U][G][A][C][G][C] = 1.400;
+ int22_ar[A][U][U][G][A][G][G][C] = 0.100;
+ int22_ar[A][U][U][G][A][U][G][C] = 1.500;
+ int22_ar[A][U][U][G][C][A][G][C] = 2.000;
+ int22_ar[A][U][U][G][C][C][G][C] = 2.000;
+ int22_ar[A][U][U][G][C][G][G][C] = 2.000;
+ int22_ar[A][U][U][G][C][U][G][C] = 2.000;
+ int22_ar[A][U][U][G][G][A][G][C] = 2.000;
+ int22_ar[A][U][U][G][G][C][G][C] = 2.100;
+ int22_ar[A][U][U][G][G][G][G][C] = 0.400;
+ int22_ar[A][U][U][G][G][U][G][C] = 1.700;
+ int22_ar[A][U][U][G][U][A][G][C] = 2.000;
+ int22_ar[A][U][U][G][U][C][G][C] = -0.300;
+ int22_ar[A][U][U][G][U][G][G][C] = -3.500;
+ int22_ar[A][U][U][G][U][U][G][C] = -0.300;
+ int22_ar[A][U][U][U][A][A][G][C] = 2.000;
+ int22_ar[A][U][U][U][A][C][G][C] = 2.000;
+ int22_ar[A][U][U][U][A][G][G][C] = 2.000;
+ int22_ar[A][U][U][U][A][U][G][C] = 2.000;
+ int22_ar[A][U][U][U][C][A][G][C] = 2.000;
+ int22_ar[A][U][U][U][C][C][G][C] = 1.600;
+ int22_ar[A][U][U][U][C][G][G][C] = 0.500;
+ int22_ar[A][U][U][U][C][U][G][C] = 0.800;
+ int22_ar[A][U][U][U][G][A][G][C] = 2.000;
+ int22_ar[A][U][U][U][G][C][G][C] = 0.100;
+ int22_ar[A][U][U][U][G][G][G][C] = -3.100;
+ int22_ar[A][U][U][U][G][U][G][C] = 0.100;
+ int22_ar[A][U][U][U][U][A][G][C] = 2.000;
+ int22_ar[A][U][U][U][U][C][G][C] = 0.800;
+ int22_ar[A][U][U][U][U][G][G][C] = 0.500;
+ int22_ar[A][U][U][U][U][U][G][C] = 0.000;
+ int22_ar[A][U][A][A][A][A][G][U] = 2.800;
+ int22_ar[A][U][A][A][A][C][G][U] = 2.600;
+ int22_ar[A][U][A][A][A][G][G][U] = 1.500;
+ int22_ar[A][U][A][A][A][U][G][U] = 2.000;
+ int22_ar[A][U][A][A][C][A][G][U] = 2.500;
+ int22_ar[A][U][A][A][C][C][G][U] = 2.400;
+ int22_ar[A][U][A][A][C][G][G][U] = 1.300;
+ int22_ar[A][U][A][A][C][U][G][U] = 2.000;
+ int22_ar[A][U][A][A][G][A][G][U] = 1.500;
+ int22_ar[A][U][A][A][G][C][G][U] = 1.400;
+ int22_ar[A][U][A][A][G][G][G][U] = 0.300;
+ int22_ar[A][U][A][A][G][U][G][U] = 2.000;
+ int22_ar[A][U][A][A][U][A][G][U] = 2.000;
+ int22_ar[A][U][A][A][U][C][G][U] = 2.000;
+ int22_ar[A][U][A][A][U][G][G][U] = 2.000;
+ int22_ar[A][U][A][A][U][U][G][U] = 2.000;
+ int22_ar[A][U][A][C][A][A][G][U] = 2.600;
+ int22_ar[A][U][A][C][A][C][G][U] = 2.500;
+ int22_ar[A][U][A][C][A][G][G][U] = 1.400;
+ int22_ar[A][U][A][C][A][U][G][U] = 2.000;
+ int22_ar[A][U][A][C][C][A][G][U] = 3.100;
+ int22_ar[A][U][A][C][C][C][G][U] = 2.300;
+ int22_ar[A][U][A][C][C][G][G][U] = 2.200;
+ int22_ar[A][U][A][C][C][U][G][U] = 2.000;
+ int22_ar[A][U][A][C][G][A][G][U] = 2.000;
+ int22_ar[A][U][A][C][G][C][G][U] = 2.000;
+ int22_ar[A][U][A][C][G][G][G][U] = 2.000;
+ int22_ar[A][U][A][C][G][U][G][U] = 2.000;
+ int22_ar[A][U][A][C][U][A][G][U] = 3.100;
+ int22_ar[A][U][A][C][U][C][G][U] = 2.300;
+ int22_ar[A][U][A][C][U][G][G][U] = 2.200;
+ int22_ar[A][U][A][C][U][U][G][U] = 2.000;
+ int22_ar[A][U][A][G][A][A][G][U] = 1.500;
+ int22_ar[A][U][A][G][A][C][G][U] = 1.400;
+ int22_ar[A][U][A][G][A][G][G][U] = 0.300;
+ int22_ar[A][U][A][G][A][U][G][U] = 2.000;
+ int22_ar[A][U][A][G][C][A][G][U] = 2.000;
+ int22_ar[A][U][A][G][C][C][G][U] = 2.000;
+ int22_ar[A][U][A][G][C][G][G][U] = 2.000;
+ int22_ar[A][U][A][G][C][U][G][U] = 2.000;
+ int22_ar[A][U][A][G][G][A][G][U] = 2.100;
+ int22_ar[A][U][A][G][G][C][G][U] = 1.900;
+ int22_ar[A][U][A][G][G][G][G][U] = 0.800;
+ int22_ar[A][U][A][G][G][U][G][U] = 2.000;
+ int22_ar[A][U][A][G][U][A][G][U] = 1.300;
+ int22_ar[A][U][A][G][U][C][G][U] = 0.200;
+ int22_ar[A][U][A][G][U][G][G][U] = 0.900;
+ int22_ar[A][U][A][G][U][U][G][U] = 2.000;
+ int22_ar[A][U][A][U][A][A][G][U] = 2.000;
+ int22_ar[A][U][A][U][A][C][G][U] = 2.000;
+ int22_ar[A][U][A][U][A][G][G][U] = 2.000;
+ int22_ar[A][U][A][U][A][U][G][U] = 2.000;
+ int22_ar[A][U][A][U][C][A][G][U] = 3.100;
+ int22_ar[A][U][A][U][C][C][G][U] = 2.300;
+ int22_ar[A][U][A][U][C][G][G][U] = 2.200;
+ int22_ar[A][U][A][U][C][U][G][U] = 2.000;
+ int22_ar[A][U][A][U][G][A][G][U] = 2.300;
+ int22_ar[A][U][A][U][G][C][G][U] = 1.200;
+ int22_ar[A][U][A][U][G][G][G][U] = 1.900;
+ int22_ar[A][U][A][U][G][U][G][U] = 2.000;
+ int22_ar[A][U][A][U][U][A][G][U] = 2.700;
+ int22_ar[A][U][A][U][U][C][G][U] = 1.500;
+ int22_ar[A][U][A][U][U][G][G][U] = 2.200;
+ int22_ar[A][U][A][U][U][U][G][U] = 2.000;
+ int22_ar[A][U][C][A][A][A][G][U] = 2.500;
+ int22_ar[A][U][C][A][A][C][G][U] = 3.100;
+ int22_ar[A][U][C][A][A][G][G][U] = 2.000;
+ int22_ar[A][U][C][A][A][U][G][U] = 3.100;
+ int22_ar[A][U][C][A][C][A][G][U] = 2.300;
+ int22_ar[A][U][C][A][C][C][G][U] = 2.200;
+ int22_ar[A][U][C][A][C][G][G][U] = 2.000;
+ int22_ar[A][U][C][A][C][U][G][U] = 2.200;
+ int22_ar[A][U][C][A][G][A][G][U] = 1.300;
+ int22_ar[A][U][C][A][G][C][G][U] = 2.200;
+ int22_ar[A][U][C][A][G][G][G][U] = 2.000;
+ int22_ar[A][U][C][A][G][U][G][U] = 2.200;
+ int22_ar[A][U][C][A][U][A][G][U] = 2.000;
+ int22_ar[A][U][C][A][U][C][G][U] = 2.000;
+ int22_ar[A][U][C][A][U][G][G][U] = 2.000;
+ int22_ar[A][U][C][A][U][U][G][U] = 2.000;
+ int22_ar[A][U][C][C][A][A][G][U] = 2.400;
+ int22_ar[A][U][C][C][A][C][G][U] = 2.300;
+ int22_ar[A][U][C][C][A][G][G][U] = 2.000;
+ int22_ar[A][U][C][C][A][U][G][U] = 2.300;
+ int22_ar[A][U][C][C][C][A][G][U] = 2.200;
+ int22_ar[A][U][C][C][C][C][G][U] = 2.200;
+ int22_ar[A][U][C][C][C][G][G][U] = 2.000;
+ int22_ar[A][U][C][C][C][U][G][U] = 2.200;
+ int22_ar[A][U][C][C][G][A][G][U] = 2.000;
+ int22_ar[A][U][C][C][G][C][G][U] = 2.000;
+ int22_ar[A][U][C][C][G][G][G][U] = 2.000;
+ int22_ar[A][U][C][C][G][U][G][U] = 2.000;
+ int22_ar[A][U][C][C][U][A][G][U] = 2.200;
+ int22_ar[A][U][C][C][U][C][G][U] = 2.200;
+ int22_ar[A][U][C][C][U][G][G][U] = 2.000;
+ int22_ar[A][U][C][C][U][U][G][U] = 2.200;
+ int22_ar[A][U][C][G][A][A][G][U] = 1.300;
+ int22_ar[A][U][C][G][A][C][G][U] = 2.200;
+ int22_ar[A][U][C][G][A][G][G][U] = 2.000;
+ int22_ar[A][U][C][G][A][U][G][U] = 2.200;
+ int22_ar[A][U][C][G][C][A][G][U] = 2.000;
+ int22_ar[A][U][C][G][C][C][G][U] = 2.000;
+ int22_ar[A][U][C][G][C][G][G][U] = 2.000;
+ int22_ar[A][U][C][G][C][U][G][U] = 2.000;
+ int22_ar[A][U][C][G][G][A][G][U] = 1.800;
+ int22_ar[A][U][C][G][G][C][G][U] = 2.400;
+ int22_ar[A][U][C][G][G][G][G][U] = 2.000;
+ int22_ar[A][U][C][G][G][U][G][U] = 2.400;
+ int22_ar[A][U][C][G][U][A][G][U] = 0.100;
+ int22_ar[A][U][C][G][U][C][G][U] = 1.000;
+ int22_ar[A][U][C][G][U][G][G][U] = 2.000;
+ int22_ar[A][U][C][G][U][U][G][U] = 1.000;
+ int22_ar[A][U][C][U][A][A][G][U] = 2.000;
+ int22_ar[A][U][C][U][A][C][G][U] = 2.000;
+ int22_ar[A][U][C][U][A][G][G][U] = 2.000;
+ int22_ar[A][U][C][U][A][U][G][U] = 2.000;
+ int22_ar[A][U][C][U][C][A][G][U] = 2.200;
+ int22_ar[A][U][C][U][C][C][G][U] = 2.200;
+ int22_ar[A][U][C][U][C][G][G][U] = 2.000;
+ int22_ar[A][U][C][U][C][U][G][U] = 2.200;
+ int22_ar[A][U][C][U][G][A][G][U] = 1.100;
+ int22_ar[A][U][C][U][G][C][G][U] = 2.000;
+ int22_ar[A][U][C][U][G][G][G][U] = 2.000;
+ int22_ar[A][U][C][U][G][U][G][U] = 2.000;
+ int22_ar[A][U][C][U][U][A][G][U] = 1.400;
+ int22_ar[A][U][C][U][U][C][G][U] = 1.400;
+ int22_ar[A][U][C][U][U][G][G][U] = 2.000;
+ int22_ar[A][U][C][U][U][U][G][U] = 1.400;
+ int22_ar[A][U][G][A][A][A][G][U] = 1.500;
+ int22_ar[A][U][G][A][A][C][G][U] = 2.000;
+ int22_ar[A][U][G][A][A][G][G][U] = 2.100;
+ int22_ar[A][U][G][A][A][U][G][U] = 2.300;
+ int22_ar[A][U][G][A][C][A][G][U] = 1.300;
+ int22_ar[A][U][G][A][C][C][G][U] = 2.000;
+ int22_ar[A][U][G][A][C][G][G][U] = 1.800;
+ int22_ar[A][U][G][A][C][U][G][U] = 1.100;
+ int22_ar[A][U][G][A][G][A][G][U] = 0.300;
+ int22_ar[A][U][G][A][G][C][G][U] = 2.000;
+ int22_ar[A][U][G][A][G][G][G][U] = 0.800;
+ int22_ar[A][U][G][A][G][U][G][U] = 1.900;
+ int22_ar[A][U][G][A][U][A][G][U] = 2.000;
+ int22_ar[A][U][G][A][U][C][G][U] = 2.000;
+ int22_ar[A][U][G][A][U][G][G][U] = 2.000;
+ int22_ar[A][U][G][A][U][U][G][U] = 2.000;
+ int22_ar[A][U][G][C][A][A][G][U] = 1.400;
+ int22_ar[A][U][G][C][A][C][G][U] = 2.000;
+ int22_ar[A][U][G][C][A][G][G][U] = 1.900;
+ int22_ar[A][U][G][C][A][U][G][U] = 1.200;
+ int22_ar[A][U][G][C][C][A][G][U] = 2.200;
+ int22_ar[A][U][G][C][C][C][G][U] = 2.000;
+ int22_ar[A][U][G][C][C][G][G][U] = 2.400;
+ int22_ar[A][U][G][C][C][U][G][U] = 2.000;
+ int22_ar[A][U][G][C][G][A][G][U] = 2.000;
+ int22_ar[A][U][G][C][G][C][G][U] = 2.000;
+ int22_ar[A][U][G][C][G][G][G][U] = 2.000;
+ int22_ar[A][U][G][C][G][U][G][U] = 2.000;
+ int22_ar[A][U][G][C][U][A][G][U] = 2.200;
+ int22_ar[A][U][G][C][U][C][G][U] = 2.000;
+ int22_ar[A][U][G][C][U][G][G][U] = 2.400;
+ int22_ar[A][U][G][C][U][U][G][U] = 2.000;
+ int22_ar[A][U][G][G][A][A][G][U] = 0.300;
+ int22_ar[A][U][G][G][A][C][G][U] = 2.000;
+ int22_ar[A][U][G][G][A][G][G][U] = 0.800;
+ int22_ar[A][U][G][G][A][U][G][U] = 1.900;
+ int22_ar[A][U][G][G][C][A][G][U] = 2.000;
+ int22_ar[A][U][G][G][C][C][G][U] = 2.000;
+ int22_ar[A][U][G][G][C][G][G][U] = 2.000;
+ int22_ar[A][U][G][G][C][U][G][U] = 2.000;
+ int22_ar[A][U][G][G][G][A][G][U] = 0.800;
+ int22_ar[A][U][G][G][G][C][G][U] = 2.000;
+ int22_ar[A][U][G][G][G][G][G][U] = 1.400;
+ int22_ar[A][U][G][G][G][U][G][U] = 1.600;
+ int22_ar[A][U][G][G][U][A][G][U] = 0.900;
+ int22_ar[A][U][G][G][U][C][G][U] = 2.000;
+ int22_ar[A][U][G][G][U][G][G][U] = 0.700;
+ int22_ar[A][U][G][G][U][U][G][U] = -1.100;
+ int22_ar[A][U][G][U][A][A][G][U] = 2.000;
+ int22_ar[A][U][G][U][A][C][G][U] = 2.000;
+ int22_ar[A][U][G][U][A][G][G][U] = 2.000;
+ int22_ar[A][U][G][U][A][U][G][U] = 2.000;
+ int22_ar[A][U][G][U][C][A][G][U] = 2.200;
+ int22_ar[A][U][G][U][C][C][G][U] = 2.000;
+ int22_ar[A][U][G][U][C][G][G][U] = 2.400;
+ int22_ar[A][U][G][U][C][U][G][U] = 2.000;
+ int22_ar[A][U][G][U][G][A][G][U] = 1.900;
+ int22_ar[A][U][G][U][G][C][G][U] = 2.000;
+ int22_ar[A][U][G][U][G][G][G][U] = 1.600;
+ int22_ar[A][U][G][U][G][U][G][U] = -0.100;
+ int22_ar[A][U][G][U][U][A][G][U] = 2.200;
+ int22_ar[A][U][G][U][U][C][G][U] = 2.000;
+ int22_ar[A][U][G][U][U][G][G][U] = 2.000;
+ int22_ar[A][U][G][U][U][U][G][U] = 2.000;
+ int22_ar[A][U][U][A][A][A][G][U] = 2.000;
+ int22_ar[A][U][U][A][A][C][G][U] = 3.100;
+ int22_ar[A][U][U][A][A][G][G][U] = 1.300;
+ int22_ar[A][U][U][A][A][U][G][U] = 2.700;
+ int22_ar[A][U][U][A][C][A][G][U] = 2.000;
+ int22_ar[A][U][U][A][C][C][G][U] = 2.200;
+ int22_ar[A][U][U][A][C][G][G][U] = 0.100;
+ int22_ar[A][U][U][A][C][U][G][U] = 1.400;
+ int22_ar[A][U][U][A][G][A][G][U] = 2.000;
+ int22_ar[A][U][U][A][G][C][G][U] = 2.200;
+ int22_ar[A][U][U][A][G][G][G][U] = 0.900;
+ int22_ar[A][U][U][A][G][U][G][U] = 2.200;
+ int22_ar[A][U][U][A][U][A][G][U] = 2.000;
+ int22_ar[A][U][U][A][U][C][G][U] = 2.000;
+ int22_ar[A][U][U][A][U][G][G][U] = 2.000;
+ int22_ar[A][U][U][A][U][U][G][U] = 2.000;
+ int22_ar[A][U][U][C][A][A][G][U] = 2.000;
+ int22_ar[A][U][U][C][A][C][G][U] = 2.300;
+ int22_ar[A][U][U][C][A][G][G][U] = 0.200;
+ int22_ar[A][U][U][C][A][U][G][U] = 1.500;
+ int22_ar[A][U][U][C][C][A][G][U] = 2.000;
+ int22_ar[A][U][U][C][C][C][G][U] = 2.200;
+ int22_ar[A][U][U][C][C][G][G][U] = 1.000;
+ int22_ar[A][U][U][C][C][U][G][U] = 1.400;
+ int22_ar[A][U][U][C][G][A][G][U] = 2.000;
+ int22_ar[A][U][U][C][G][C][G][U] = 2.000;
+ int22_ar[A][U][U][C][G][G][G][U] = 2.000;
+ int22_ar[A][U][U][C][G][U][G][U] = 2.000;
+ int22_ar[A][U][U][C][U][A][G][U] = 2.000;
+ int22_ar[A][U][U][C][U][C][G][U] = 2.200;
+ int22_ar[A][U][U][C][U][G][G][U] = 1.000;
+ int22_ar[A][U][U][C][U][U][G][U] = 1.400;
+ int22_ar[A][U][U][G][A][A][G][U] = 2.000;
+ int22_ar[A][U][U][G][A][C][G][U] = 2.200;
+ int22_ar[A][U][U][G][A][G][G][U] = 0.900;
+ int22_ar[A][U][U][G][A][U][G][U] = 2.200;
+ int22_ar[A][U][U][G][C][A][G][U] = 2.000;
+ int22_ar[A][U][U][G][C][C][G][U] = 2.000;
+ int22_ar[A][U][U][G][C][G][G][U] = 2.000;
+ int22_ar[A][U][U][G][C][U][G][U] = 2.000;
+ int22_ar[A][U][U][G][G][A][G][U] = 2.000;
+ int22_ar[A][U][U][G][G][C][G][U] = 2.400;
+ int22_ar[A][U][U][G][G][G][G][U] = 0.700;
+ int22_ar[A][U][U][G][G][U][G][U] = 2.000;
+ int22_ar[A][U][U][G][U][A][G][U] = 2.000;
+ int22_ar[A][U][U][G][U][C][G][U] = 1.000;
+ int22_ar[A][U][U][G][U][G][G][U] = -2.100;
+ int22_ar[A][U][U][G][U][U][G][U] = 1.100;
+ int22_ar[A][U][U][U][A][A][G][U] = 2.000;
+ int22_ar[A][U][U][U][A][C][G][U] = 2.000;
+ int22_ar[A][U][U][U][A][G][G][U] = 2.000;
+ int22_ar[A][U][U][U][A][U][G][U] = 2.000;
+ int22_ar[A][U][U][U][C][A][G][U] = 2.000;
+ int22_ar[A][U][U][U][C][C][G][U] = 2.200;
+ int22_ar[A][U][U][U][C][G][G][U] = 1.000;
+ int22_ar[A][U][U][U][C][U][G][U] = 1.400;
+ int22_ar[A][U][U][U][G][A][G][U] = 2.000;
+ int22_ar[A][U][U][U][G][C][G][U] = 2.000;
+ int22_ar[A][U][U][U][G][G][G][U] = -1.100;
+ int22_ar[A][U][U][U][G][U][G][U] = 2.000;
+ int22_ar[A][U][U][U][U][A][G][U] = 2.000;
+ int22_ar[A][U][U][U][U][C][G][U] = 1.400;
+ int22_ar[A][U][U][U][U][G][G][U] = 1.100;
+ int22_ar[A][U][U][U][U][U][G][U] = 0.600;
+ int22_ar[A][U][A][A][A][A][U][A] = 2.800;
+ int22_ar[A][U][A][A][A][C][U][A] = 2.600;
+ int22_ar[A][U][A][A][A][G][U][A] = 1.500;
+ int22_ar[A][U][A][A][A][U][U][A] = 2.000;
+ int22_ar[A][U][A][A][C][A][U][A] = 2.300;
+ int22_ar[A][U][A][A][C][C][U][A] = 2.200;
+ int22_ar[A][U][A][A][C][G][U][A] = 1.100;
+ int22_ar[A][U][A][A][C][U][U][A] = 2.000;
+ int22_ar[A][U][A][A][G][A][U][A] = 1.700;
+ int22_ar[A][U][A][A][G][C][U][A] = 1.600;
+ int22_ar[A][U][A][A][G][G][U][A] = 0.500;
+ int22_ar[A][U][A][A][G][U][U][A] = 2.000;
+ int22_ar[A][U][A][A][U][A][U][A] = 2.000;
+ int22_ar[A][U][A][A][U][C][U][A] = 2.000;
+ int22_ar[A][U][A][A][U][G][U][A] = 2.000;
+ int22_ar[A][U][A][A][U][U][U][A] = 2.000;
+ int22_ar[A][U][A][C][A][A][U][A] = 2.800;
+ int22_ar[A][U][A][C][A][C][U][A] = 2.600;
+ int22_ar[A][U][A][C][A][G][U][A] = 1.500;
+ int22_ar[A][U][A][C][A][U][U][A] = 2.000;
+ int22_ar[A][U][A][C][C][A][U][A] = 3.400;
+ int22_ar[A][U][A][C][C][C][U][A] = 2.600;
+ int22_ar[A][U][A][C][C][G][U][A] = 2.500;
+ int22_ar[A][U][A][C][C][U][U][A] = 2.000;
+ int22_ar[A][U][A][C][G][A][U][A] = 2.000;
+ int22_ar[A][U][A][C][G][C][U][A] = 2.000;
+ int22_ar[A][U][A][C][G][G][U][A] = 2.000;
+ int22_ar[A][U][A][C][G][U][U][A] = 2.000;
+ int22_ar[A][U][A][C][U][A][U][A] = 3.400;
+ int22_ar[A][U][A][C][U][C][U][A] = 2.600;
+ int22_ar[A][U][A][C][U][G][U][A] = 2.500;
+ int22_ar[A][U][A][C][U][U][U][A] = 2.000;
+ int22_ar[A][U][A][G][A][A][U][A] = 1.700;
+ int22_ar[A][U][A][G][A][C][U][A] = 1.600;
+ int22_ar[A][U][A][G][A][G][U][A] = 0.500;
+ int22_ar[A][U][A][G][A][U][U][A] = 2.000;
+ int22_ar[A][U][A][G][C][A][U][A] = 2.000;
+ int22_ar[A][U][A][G][C][C][U][A] = 2.000;
+ int22_ar[A][U][A][G][C][G][U][A] = 2.000;
+ int22_ar[A][U][A][G][C][U][U][A] = 2.000;
+ int22_ar[A][U][A][G][G][A][U][A] = 2.100;
+ int22_ar[A][U][A][G][G][C][U][A] = 2.000;
+ int22_ar[A][U][A][G][G][G][U][A] = 0.900;
+ int22_ar[A][U][A][G][G][U][U][A] = 2.000;
+ int22_ar[A][U][A][G][U][A][U][A] = 1.000;
+ int22_ar[A][U][A][G][U][C][U][A] = -0.200;
+ int22_ar[A][U][A][G][U][G][U][A] = 0.500;
+ int22_ar[A][U][A][G][U][U][U][A] = 2.000;
+ int22_ar[A][U][A][U][A][A][U][A] = 2.000;
+ int22_ar[A][U][A][U][A][C][U][A] = 2.000;
+ int22_ar[A][U][A][U][A][G][U][A] = 2.000;
+ int22_ar[A][U][A][U][A][U][U][A] = 2.000;
+ int22_ar[A][U][A][U][C][A][U][A] = 3.100;
+ int22_ar[A][U][A][U][C][C][U][A] = 2.300;
+ int22_ar[A][U][A][U][C][G][U][A] = 2.200;
+ int22_ar[A][U][A][U][C][U][U][A] = 2.000;
+ int22_ar[A][U][A][U][G][A][U][A] = 2.200;
+ int22_ar[A][U][A][U][G][C][U][A] = 1.100;
+ int22_ar[A][U][A][U][G][G][U][A] = 1.800;
+ int22_ar[A][U][A][U][G][U][U][A] = 2.000;
+ int22_ar[A][U][A][U][U][A][U][A] = 2.900;
+ int22_ar[A][U][A][U][U][C][U][A] = 1.800;
+ int22_ar[A][U][A][U][U][G][U][A] = 2.500;
+ int22_ar[A][U][A][U][U][U][U][A] = 2.000;
+ int22_ar[A][U][C][A][A][A][U][A] = 2.500;
+ int22_ar[A][U][C][A][A][C][U][A] = 3.100;
+ int22_ar[A][U][C][A][A][G][U][A] = 2.000;
+ int22_ar[A][U][C][A][A][U][U][A] = 3.100;
+ int22_ar[A][U][C][A][C][A][U][A] = 2.100;
+ int22_ar[A][U][C][A][C][C][U][A] = 2.000;
+ int22_ar[A][U][C][A][C][G][U][A] = 2.000;
+ int22_ar[A][U][C][A][C][U][U][A] = 2.000;
+ int22_ar[A][U][C][A][G][A][U][A] = 1.500;
+ int22_ar[A][U][C][A][G][C][U][A] = 2.400;
+ int22_ar[A][U][C][A][G][G][U][A] = 2.000;
+ int22_ar[A][U][C][A][G][U][U][A] = 2.400;
+ int22_ar[A][U][C][A][U][A][U][A] = 2.000;
+ int22_ar[A][U][C][A][U][C][U][A] = 2.000;
+ int22_ar[A][U][C][A][U][G][U][A] = 2.000;
+ int22_ar[A][U][C][A][U][U][U][A] = 2.000;
+ int22_ar[A][U][C][C][A][A][U][A] = 2.500;
+ int22_ar[A][U][C][C][A][C][U][A] = 2.500;
+ int22_ar[A][U][C][C][A][G][U][A] = 2.000;
+ int22_ar[A][U][C][C][A][U][U][A] = 2.500;
+ int22_ar[A][U][C][C][C][A][U][A] = 2.500;
+ int22_ar[A][U][C][C][C][C][U][A] = 2.500;
+ int22_ar[A][U][C][C][C][G][U][A] = 2.000;
+ int22_ar[A][U][C][C][C][U][U][A] = 2.500;
+ int22_ar[A][U][C][C][G][A][U][A] = 2.000;
+ int22_ar[A][U][C][C][G][C][U][A] = 2.000;
+ int22_ar[A][U][C][C][G][G][U][A] = 2.000;
+ int22_ar[A][U][C][C][G][U][U][A] = 2.000;
+ int22_ar[A][U][C][C][U][A][U][A] = 2.500;
+ int22_ar[A][U][C][C][U][C][U][A] = 2.500;
+ int22_ar[A][U][C][C][U][G][U][A] = 2.000;
+ int22_ar[A][U][C][C][U][U][U][A] = 2.500;
+ int22_ar[A][U][C][G][A][A][U][A] = 1.500;
+ int22_ar[A][U][C][G][A][C][U][A] = 2.400;
+ int22_ar[A][U][C][G][A][G][U][A] = 2.000;
+ int22_ar[A][U][C][G][A][U][U][A] = 2.400;
+ int22_ar[A][U][C][G][C][A][U][A] = 2.000;
+ int22_ar[A][U][C][G][C][C][U][A] = 2.000;
+ int22_ar[A][U][C][G][C][G][U][A] = 2.000;
+ int22_ar[A][U][C][G][C][U][U][A] = 2.000;
+ int22_ar[A][U][C][G][G][A][U][A] = 1.900;
+ int22_ar[A][U][C][G][G][C][U][A] = 2.400;
+ int22_ar[A][U][C][G][G][G][U][A] = 2.000;
+ int22_ar[A][U][C][G][G][U][U][A] = 2.400;
+ int22_ar[A][U][C][G][U][A][U][A] = -0.300;
+ int22_ar[A][U][C][G][U][C][U][A] = 0.700;
+ int22_ar[A][U][C][G][U][G][U][A] = 2.000;
+ int22_ar[A][U][C][G][U][U][U][A] = 0.700;
+ int22_ar[A][U][C][U][A][A][U][A] = 2.000;
+ int22_ar[A][U][C][U][A][C][U][A] = 2.000;
+ int22_ar[A][U][C][U][A][G][U][A] = 2.000;
+ int22_ar[A][U][C][U][A][U][U][A] = 2.000;
+ int22_ar[A][U][C][U][C][A][U][A] = 2.200;
+ int22_ar[A][U][C][U][C][C][U][A] = 2.200;
+ int22_ar[A][U][C][U][C][G][U][A] = 2.000;
+ int22_ar[A][U][C][U][C][U][U][A] = 2.200;
+ int22_ar[A][U][C][U][G][A][U][A] = 1.000;
+ int22_ar[A][U][C][U][G][C][U][A] = 1.900;
+ int22_ar[A][U][C][U][G][G][U][A] = 2.000;
+ int22_ar[A][U][C][U][G][U][U][A] = 1.900;
+ int22_ar[A][U][C][U][U][A][U][A] = 1.700;
+ int22_ar[A][U][C][U][U][C][U][A] = 1.600;
+ int22_ar[A][U][C][U][U][G][U][A] = 2.000;
+ int22_ar[A][U][C][U][U][U][U][A] = 1.600;
+ int22_ar[A][U][G][A][A][A][U][A] = 1.500;
+ int22_ar[A][U][G][A][A][C][U][A] = 2.000;
+ int22_ar[A][U][G][A][A][G][U][A] = 2.100;
+ int22_ar[A][U][G][A][A][U][U][A] = 2.300;
+ int22_ar[A][U][G][A][C][A][U][A] = 1.100;
+ int22_ar[A][U][G][A][C][C][U][A] = 2.000;
+ int22_ar[A][U][G][A][C][G][U][A] = 1.600;
+ int22_ar[A][U][G][A][C][U][U][A] = 0.900;
+ int22_ar[A][U][G][A][G][A][U][A] = 0.500;
+ int22_ar[A][U][G][A][G][C][U][A] = 2.000;
+ int22_ar[A][U][G][A][G][G][U][A] = 1.000;
+ int22_ar[A][U][G][A][G][U][U][A] = 2.100;
+ int22_ar[A][U][G][A][U][A][U][A] = 2.000;
+ int22_ar[A][U][G][A][U][C][U][A] = 2.000;
+ int22_ar[A][U][G][A][U][G][U][A] = 2.000;
+ int22_ar[A][U][G][A][U][U][U][A] = 2.000;
+ int22_ar[A][U][G][C][A][A][U][A] = 1.500;
+ int22_ar[A][U][G][C][A][C][U][A] = 2.000;
+ int22_ar[A][U][G][C][A][G][U][A] = 2.100;
+ int22_ar[A][U][G][C][A][U][U][A] = 1.300;
+ int22_ar[A][U][G][C][C][A][U][A] = 2.500;
+ int22_ar[A][U][G][C][C][C][U][A] = 2.000;
+ int22_ar[A][U][G][C][C][G][U][A] = 2.700;
+ int22_ar[A][U][G][C][C][U][U][A] = 2.300;
+ int22_ar[A][U][G][C][G][A][U][A] = 2.000;
+ int22_ar[A][U][G][C][G][C][U][A] = 2.000;
+ int22_ar[A][U][G][C][G][G][U][A] = 2.000;
+ int22_ar[A][U][G][C][G][U][U][A] = 2.000;
+ int22_ar[A][U][G][C][U][A][U][A] = 2.500;
+ int22_ar[A][U][G][C][U][C][U][A] = 2.000;
+ int22_ar[A][U][G][C][U][G][U][A] = 2.700;
+ int22_ar[A][U][G][C][U][U][U][A] = 2.300;
+ int22_ar[A][U][G][G][A][A][U][A] = 0.500;
+ int22_ar[A][U][G][G][A][C][U][A] = 2.000;
+ int22_ar[A][U][G][G][A][G][U][A] = 1.000;
+ int22_ar[A][U][G][G][A][U][U][A] = 2.100;
+ int22_ar[A][U][G][G][C][A][U][A] = 2.000;
+ int22_ar[A][U][G][G][C][C][U][A] = 2.000;
+ int22_ar[A][U][G][G][C][G][U][A] = 2.000;
+ int22_ar[A][U][G][G][C][U][U][A] = 2.000;
+ int22_ar[A][U][G][G][G][A][U][A] = 0.900;
+ int22_ar[A][U][G][G][G][C][U][A] = 2.000;
+ int22_ar[A][U][G][G][G][G][U][A] = 1.400;
+ int22_ar[A][U][G][G][G][U][U][A] = 1.700;
+ int22_ar[A][U][G][G][U][A][U][A] = 0.500;
+ int22_ar[A][U][G][G][U][C][U][A] = 2.000;
+ int22_ar[A][U][G][G][U][G][U][A] = 0.300;
+ int22_ar[A][U][G][G][U][U][U][A] = -1.500;
+ int22_ar[A][U][G][U][A][A][U][A] = 2.000;
+ int22_ar[A][U][G][U][A][C][U][A] = 2.000;
+ int22_ar[A][U][G][U][A][G][U][A] = 2.000;
+ int22_ar[A][U][G][U][A][U][U][A] = 2.000;
+ int22_ar[A][U][G][U][C][A][U][A] = 2.200;
+ int22_ar[A][U][G][U][C][C][U][A] = 2.000;
+ int22_ar[A][U][G][U][C][G][U][A] = 2.400;
+ int22_ar[A][U][G][U][C][U][U][A] = 2.000;
+ int22_ar[A][U][G][U][G][A][U][A] = 1.800;
+ int22_ar[A][U][G][U][G][C][U][A] = 2.000;
+ int22_ar[A][U][G][U][G][G][U][A] = 1.500;
+ int22_ar[A][U][G][U][G][U][U][A] = -0.200;
+ int22_ar[A][U][G][U][U][A][U][A] = 2.500;
+ int22_ar[A][U][G][U][U][C][U][A] = 2.000;
+ int22_ar[A][U][G][U][U][G][U][A] = 2.200;
+ int22_ar[A][U][G][U][U][U][U][A] = 2.300;
+ int22_ar[A][U][U][A][A][A][U][A] = 2.000;
+ int22_ar[A][U][U][A][A][C][U][A] = 3.100;
+ int22_ar[A][U][U][A][A][G][U][A] = 1.300;
+ int22_ar[A][U][U][A][A][U][U][A] = 2.700;
+ int22_ar[A][U][U][A][C][A][U][A] = 2.000;
+ int22_ar[A][U][U][A][C][C][U][A] = 2.000;
+ int22_ar[A][U][U][A][C][G][U][A] = -0.100;
+ int22_ar[A][U][U][A][C][U][U][A] = 1.200;
+ int22_ar[A][U][U][A][G][A][U][A] = 2.000;
+ int22_ar[A][U][U][A][G][C][U][A] = 2.400;
+ int22_ar[A][U][U][A][G][G][U][A] = 1.100;
+ int22_ar[A][U][U][A][G][U][U][A] = 2.400;
+ int22_ar[A][U][U][A][U][A][U][A] = 2.000;
+ int22_ar[A][U][U][A][U][C][U][A] = 2.000;
+ int22_ar[A][U][U][A][U][G][U][A] = 2.000;
+ int22_ar[A][U][U][A][U][U][U][A] = 2.000;
+ int22_ar[A][U][U][C][A][A][U][A] = 2.000;
+ int22_ar[A][U][U][C][A][C][U][A] = 2.500;
+ int22_ar[A][U][U][C][A][G][U][A] = 0.300;
+ int22_ar[A][U][U][C][A][U][U][A] = 1.700;
+ int22_ar[A][U][U][C][C][A][U][A] = 2.000;
+ int22_ar[A][U][U][C][C][C][U][A] = 2.500;
+ int22_ar[A][U][U][C][C][G][U][A] = 1.300;
+ int22_ar[A][U][U][C][C][U][U][A] = 1.700;
+ int22_ar[A][U][U][C][G][A][U][A] = 2.000;
+ int22_ar[A][U][U][C][G][C][U][A] = 2.000;
+ int22_ar[A][U][U][C][G][G][U][A] = 2.000;
+ int22_ar[A][U][U][C][G][U][U][A] = 2.000;
+ int22_ar[A][U][U][C][U][A][U][A] = 2.000;
+ int22_ar[A][U][U][C][U][C][U][A] = 2.500;
+ int22_ar[A][U][U][C][U][G][U][A] = 1.300;
+ int22_ar[A][U][U][C][U][U][U][A] = 1.700;
+ int22_ar[A][U][U][G][A][A][U][A] = 2.000;
+ int22_ar[A][U][U][G][A][C][U][A] = 2.400;
+ int22_ar[A][U][U][G][A][G][U][A] = 1.100;
+ int22_ar[A][U][U][G][A][U][U][A] = 2.400;
+ int22_ar[A][U][U][G][C][A][U][A] = 2.000;
+ int22_ar[A][U][U][G][C][C][U][A] = 2.000;
+ int22_ar[A][U][U][G][C][G][U][A] = 2.000;
+ int22_ar[A][U][U][G][C][U][U][A] = 2.000;
+ int22_ar[A][U][U][G][G][A][U][A] = 2.000;
+ int22_ar[A][U][U][G][G][C][U][A] = 2.400;
+ int22_ar[A][U][U][G][G][G][U][A] = 0.700;
+ int22_ar[A][U][U][G][G][U][U][A] = 2.000;
+ int22_ar[A][U][U][G][U][A][U][A] = 2.000;
+ int22_ar[A][U][U][G][U][C][U][A] = 0.700;
+ int22_ar[A][U][U][G][U][G][U][A] = -2.500;
+ int22_ar[A][U][U][G][U][U][U][A] = 0.700;
+ int22_ar[A][U][U][U][A][A][U][A] = 2.000;
+ int22_ar[A][U][U][U][A][C][U][A] = 2.000;
+ int22_ar[A][U][U][U][A][G][U][A] = 2.000;
+ int22_ar[A][U][U][U][A][U][U][A] = 2.000;
+ int22_ar[A][U][U][U][C][A][U][A] = 2.000;
+ int22_ar[A][U][U][U][C][C][U][A] = 2.200;
+ int22_ar[A][U][U][U][C][G][U][A] = 1.000;
+ int22_ar[A][U][U][U][C][U][U][A] = 1.400;
+ int22_ar[A][U][U][U][G][A][U][A] = 2.000;
+ int22_ar[A][U][U][U][G][C][U][A] = 1.900;
+ int22_ar[A][U][U][U][G][G][U][A] = -1.200;
+ int22_ar[A][U][U][U][G][U][U][A] = 1.900;
+ int22_ar[A][U][U][U][U][A][U][A] = 2.000;
+ int22_ar[A][U][U][U][U][C][U][A] = 1.600;
+ int22_ar[A][U][U][U][U][G][U][A] = 1.300;
+ int22_ar[A][U][U][U][U][U][U][A] = 0.800;
+ int22_ar[A][U][A][A][A][A][U][G] = 2.800;
+ int22_ar[A][U][A][A][A][C][U][G] = 2.600;
+ int22_ar[A][U][A][A][A][G][U][G] = 1.500;
+ int22_ar[A][U][A][A][A][U][U][G] = 2.000;
+ int22_ar[A][U][A][A][C][A][U][G] = 2.300;
+ int22_ar[A][U][A][A][C][C][U][G] = 2.200;
+ int22_ar[A][U][A][A][C][G][U][G] = 1.100;
+ int22_ar[A][U][A][A][C][U][U][G] = 2.000;
+ int22_ar[A][U][A][A][G][A][U][G] = 1.700;
+ int22_ar[A][U][A][A][G][C][U][G] = 1.600;
+ int22_ar[A][U][A][A][G][G][U][G] = 0.500;
+ int22_ar[A][U][A][A][G][U][U][G] = 2.000;
+ int22_ar[A][U][A][A][U][A][U][G] = 2.000;
+ int22_ar[A][U][A][A][U][C][U][G] = 2.000;
+ int22_ar[A][U][A][A][U][G][U][G] = 2.000;
+ int22_ar[A][U][A][A][U][U][U][G] = 2.000;
+ int22_ar[A][U][A][C][A][A][U][G] = 2.800;
+ int22_ar[A][U][A][C][A][C][U][G] = 2.600;
+ int22_ar[A][U][A][C][A][G][U][G] = 1.500;
+ int22_ar[A][U][A][C][A][U][U][G] = 2.000;
+ int22_ar[A][U][A][C][C][A][U][G] = 3.400;
+ int22_ar[A][U][A][C][C][C][U][G] = 2.600;
+ int22_ar[A][U][A][C][C][G][U][G] = 2.500;
+ int22_ar[A][U][A][C][C][U][U][G] = 2.000;
+ int22_ar[A][U][A][C][G][A][U][G] = 2.000;
+ int22_ar[A][U][A][C][G][C][U][G] = 2.000;
+ int22_ar[A][U][A][C][G][G][U][G] = 2.000;
+ int22_ar[A][U][A][C][G][U][U][G] = 2.000;
+ int22_ar[A][U][A][C][U][A][U][G] = 3.400;
+ int22_ar[A][U][A][C][U][C][U][G] = 2.600;
+ int22_ar[A][U][A][C][U][G][U][G] = 2.500;
+ int22_ar[A][U][A][C][U][U][U][G] = 2.000;
+ int22_ar[A][U][A][G][A][A][U][G] = 1.700;
+ int22_ar[A][U][A][G][A][C][U][G] = 1.600;
+ int22_ar[A][U][A][G][A][G][U][G] = 0.500;
+ int22_ar[A][U][A][G][A][U][U][G] = 2.000;
+ int22_ar[A][U][A][G][C][A][U][G] = 2.000;
+ int22_ar[A][U][A][G][C][C][U][G] = 2.000;
+ int22_ar[A][U][A][G][C][G][U][G] = 2.000;
+ int22_ar[A][U][A][G][C][U][U][G] = 2.000;
+ int22_ar[A][U][A][G][G][A][U][G] = 2.100;
+ int22_ar[A][U][A][G][G][C][U][G] = 2.000;
+ int22_ar[A][U][A][G][G][G][U][G] = 0.900;
+ int22_ar[A][U][A][G][G][U][U][G] = 2.000;
+ int22_ar[A][U][A][G][U][A][U][G] = 1.000;
+ int22_ar[A][U][A][G][U][C][U][G] = -0.200;
+ int22_ar[A][U][A][G][U][G][U][G] = 0.500;
+ int22_ar[A][U][A][G][U][U][U][G] = 2.000;
+ int22_ar[A][U][A][U][A][A][U][G] = 2.000;
+ int22_ar[A][U][A][U][A][C][U][G] = 2.000;
+ int22_ar[A][U][A][U][A][G][U][G] = 2.000;
+ int22_ar[A][U][A][U][A][U][U][G] = 2.000;
+ int22_ar[A][U][A][U][C][A][U][G] = 3.100;
+ int22_ar[A][U][A][U][C][C][U][G] = 2.300;
+ int22_ar[A][U][A][U][C][G][U][G] = 2.200;
+ int22_ar[A][U][A][U][C][U][U][G] = 2.000;
+ int22_ar[A][U][A][U][G][A][U][G] = 2.200;
+ int22_ar[A][U][A][U][G][C][U][G] = 1.100;
+ int22_ar[A][U][A][U][G][G][U][G] = 1.800;
+ int22_ar[A][U][A][U][G][U][U][G] = 2.000;
+ int22_ar[A][U][A][U][U][A][U][G] = 2.900;
+ int22_ar[A][U][A][U][U][C][U][G] = 1.800;
+ int22_ar[A][U][A][U][U][G][U][G] = 2.500;
+ int22_ar[A][U][A][U][U][U][U][G] = 2.000;
+ int22_ar[A][U][C][A][A][A][U][G] = 2.500;
+ int22_ar[A][U][C][A][A][C][U][G] = 3.100;
+ int22_ar[A][U][C][A][A][G][U][G] = 2.000;
+ int22_ar[A][U][C][A][A][U][U][G] = 3.100;
+ int22_ar[A][U][C][A][C][A][U][G] = 2.100;
+ int22_ar[A][U][C][A][C][C][U][G] = 2.000;
+ int22_ar[A][U][C][A][C][G][U][G] = 2.000;
+ int22_ar[A][U][C][A][C][U][U][G] = 2.000;
+ int22_ar[A][U][C][A][G][A][U][G] = 1.500;
+ int22_ar[A][U][C][A][G][C][U][G] = 2.400;
+ int22_ar[A][U][C][A][G][G][U][G] = 2.000;
+ int22_ar[A][U][C][A][G][U][U][G] = 2.400;
+ int22_ar[A][U][C][A][U][A][U][G] = 2.000;
+ int22_ar[A][U][C][A][U][C][U][G] = 2.000;
+ int22_ar[A][U][C][A][U][G][U][G] = 2.000;
+ int22_ar[A][U][C][A][U][U][U][G] = 2.000;
+ int22_ar[A][U][C][C][A][A][U][G] = 2.500;
+ int22_ar[A][U][C][C][A][C][U][G] = 2.500;
+ int22_ar[A][U][C][C][A][G][U][G] = 2.000;
+ int22_ar[A][U][C][C][A][U][U][G] = 2.500;
+ int22_ar[A][U][C][C][C][A][U][G] = 2.500;
+ int22_ar[A][U][C][C][C][C][U][G] = 2.500;
+ int22_ar[A][U][C][C][C][G][U][G] = 2.000;
+ int22_ar[A][U][C][C][C][U][U][G] = 2.500;
+ int22_ar[A][U][C][C][G][A][U][G] = 2.000;
+ int22_ar[A][U][C][C][G][C][U][G] = 2.000;
+ int22_ar[A][U][C][C][G][G][U][G] = 2.000;
+ int22_ar[A][U][C][C][G][U][U][G] = 2.000;
+ int22_ar[A][U][C][C][U][A][U][G] = 2.500;
+ int22_ar[A][U][C][C][U][C][U][G] = 2.500;
+ int22_ar[A][U][C][C][U][G][U][G] = 2.000;
+ int22_ar[A][U][C][C][U][U][U][G] = 2.500;
+ int22_ar[A][U][C][G][A][A][U][G] = 1.500;
+ int22_ar[A][U][C][G][A][C][U][G] = 2.400;
+ int22_ar[A][U][C][G][A][G][U][G] = 2.000;
+ int22_ar[A][U][C][G][A][U][U][G] = 2.400;
+ int22_ar[A][U][C][G][C][A][U][G] = 2.000;
+ int22_ar[A][U][C][G][C][C][U][G] = 2.000;
+ int22_ar[A][U][C][G][C][G][U][G] = 2.000;
+ int22_ar[A][U][C][G][C][U][U][G] = 2.000;
+ int22_ar[A][U][C][G][G][A][U][G] = 1.900;
+ int22_ar[A][U][C][G][G][C][U][G] = 2.400;
+ int22_ar[A][U][C][G][G][G][U][G] = 2.000;
+ int22_ar[A][U][C][G][G][U][U][G] = 2.400;
+ int22_ar[A][U][C][G][U][A][U][G] = -0.300;
+ int22_ar[A][U][C][G][U][C][U][G] = 0.700;
+ int22_ar[A][U][C][G][U][G][U][G] = 2.000;
+ int22_ar[A][U][C][G][U][U][U][G] = 0.700;
+ int22_ar[A][U][C][U][A][A][U][G] = 2.000;
+ int22_ar[A][U][C][U][A][C][U][G] = 2.000;
+ int22_ar[A][U][C][U][A][G][U][G] = 2.000;
+ int22_ar[A][U][C][U][A][U][U][G] = 2.000;
+ int22_ar[A][U][C][U][C][A][U][G] = 2.200;
+ int22_ar[A][U][C][U][C][C][U][G] = 2.200;
+ int22_ar[A][U][C][U][C][G][U][G] = 2.000;
+ int22_ar[A][U][C][U][C][U][U][G] = 2.200;
+ int22_ar[A][U][C][U][G][A][U][G] = 1.000;
+ int22_ar[A][U][C][U][G][C][U][G] = 1.900;
+ int22_ar[A][U][C][U][G][G][U][G] = 2.000;
+ int22_ar[A][U][C][U][G][U][U][G] = 1.900;
+ int22_ar[A][U][C][U][U][A][U][G] = 1.700;
+ int22_ar[A][U][C][U][U][C][U][G] = 1.600;
+ int22_ar[A][U][C][U][U][G][U][G] = 2.000;
+ int22_ar[A][U][C][U][U][U][U][G] = 1.600;
+ int22_ar[A][U][G][A][A][A][U][G] = 1.500;
+ int22_ar[A][U][G][A][A][C][U][G] = 2.000;
+ int22_ar[A][U][G][A][A][G][U][G] = 2.100;
+ int22_ar[A][U][G][A][A][U][U][G] = 2.300;
+ int22_ar[A][U][G][A][C][A][U][G] = 1.100;
+ int22_ar[A][U][G][A][C][C][U][G] = 2.000;
+ int22_ar[A][U][G][A][C][G][U][G] = 1.600;
+ int22_ar[A][U][G][A][C][U][U][G] = 0.900;
+ int22_ar[A][U][G][A][G][A][U][G] = 0.500;
+ int22_ar[A][U][G][A][G][C][U][G] = 2.000;
+ int22_ar[A][U][G][A][G][G][U][G] = 1.000;
+ int22_ar[A][U][G][A][G][U][U][G] = 2.100;
+ int22_ar[A][U][G][A][U][A][U][G] = 2.000;
+ int22_ar[A][U][G][A][U][C][U][G] = 2.000;
+ int22_ar[A][U][G][A][U][G][U][G] = 2.000;
+ int22_ar[A][U][G][A][U][U][U][G] = 2.000;
+ int22_ar[A][U][G][C][A][A][U][G] = 1.500;
+ int22_ar[A][U][G][C][A][C][U][G] = 2.000;
+ int22_ar[A][U][G][C][A][G][U][G] = 2.100;
+ int22_ar[A][U][G][C][A][U][U][G] = 1.300;
+ int22_ar[A][U][G][C][C][A][U][G] = 2.500;
+ int22_ar[A][U][G][C][C][C][U][G] = 2.000;
+ int22_ar[A][U][G][C][C][G][U][G] = 2.700;
+ int22_ar[A][U][G][C][C][U][U][G] = 2.300;
+ int22_ar[A][U][G][C][G][A][U][G] = 2.000;
+ int22_ar[A][U][G][C][G][C][U][G] = 2.000;
+ int22_ar[A][U][G][C][G][G][U][G] = 2.000;
+ int22_ar[A][U][G][C][G][U][U][G] = 2.000;
+ int22_ar[A][U][G][C][U][A][U][G] = 2.500;
+ int22_ar[A][U][G][C][U][C][U][G] = 2.000;
+ int22_ar[A][U][G][C][U][G][U][G] = 2.700;
+ int22_ar[A][U][G][C][U][U][U][G] = 2.300;
+ int22_ar[A][U][G][G][A][A][U][G] = 0.500;
+ int22_ar[A][U][G][G][A][C][U][G] = 2.000;
+ int22_ar[A][U][G][G][A][G][U][G] = 1.000;
+ int22_ar[A][U][G][G][A][U][U][G] = 2.100;
+ int22_ar[A][U][G][G][C][A][U][G] = 2.000;
+ int22_ar[A][U][G][G][C][C][U][G] = 2.000;
+ int22_ar[A][U][G][G][C][G][U][G] = 2.000;
+ int22_ar[A][U][G][G][C][U][U][G] = 2.000;
+ int22_ar[A][U][G][G][G][A][U][G] = 0.900;
+ int22_ar[A][U][G][G][G][C][U][G] = 2.000;
+ int22_ar[A][U][G][G][G][G][U][G] = 1.400;
+ int22_ar[A][U][G][G][G][U][U][G] = 1.700;
+ int22_ar[A][U][G][G][U][A][U][G] = 0.500;
+ int22_ar[A][U][G][G][U][C][U][G] = 2.000;
+ int22_ar[A][U][G][G][U][G][U][G] = 0.300;
+ int22_ar[A][U][G][G][U][U][U][G] = -1.500;
+ int22_ar[A][U][G][U][A][A][U][G] = 2.000;
+ int22_ar[A][U][G][U][A][C][U][G] = 2.000;
+ int22_ar[A][U][G][U][A][G][U][G] = 2.000;
+ int22_ar[A][U][G][U][A][U][U][G] = 2.000;
+ int22_ar[A][U][G][U][C][A][U][G] = 2.200;
+ int22_ar[A][U][G][U][C][C][U][G] = 2.000;
+ int22_ar[A][U][G][U][C][G][U][G] = 2.400;
+ int22_ar[A][U][G][U][C][U][U][G] = 2.000;
+ int22_ar[A][U][G][U][G][A][U][G] = 1.800;
+ int22_ar[A][U][G][U][G][C][U][G] = 2.000;
+ int22_ar[A][U][G][U][G][G][U][G] = 1.500;
+ int22_ar[A][U][G][U][G][U][U][G] = -0.200;
+ int22_ar[A][U][G][U][U][A][U][G] = 2.500;
+ int22_ar[A][U][G][U][U][C][U][G] = 2.000;
+ int22_ar[A][U][G][U][U][G][U][G] = 2.200;
+ int22_ar[A][U][G][U][U][U][U][G] = 2.300;
+ int22_ar[A][U][U][A][A][A][U][G] = 2.000;
+ int22_ar[A][U][U][A][A][C][U][G] = 3.100;
+ int22_ar[A][U][U][A][A][G][U][G] = 1.300;
+ int22_ar[A][U][U][A][A][U][U][G] = 2.700;
+ int22_ar[A][U][U][A][C][A][U][G] = 2.000;
+ int22_ar[A][U][U][A][C][C][U][G] = 2.000;
+ int22_ar[A][U][U][A][C][G][U][G] = -0.100;
+ int22_ar[A][U][U][A][C][U][U][G] = 1.200;
+ int22_ar[A][U][U][A][G][A][U][G] = 2.000;
+ int22_ar[A][U][U][A][G][C][U][G] = 2.400;
+ int22_ar[A][U][U][A][G][G][U][G] = 1.100;
+ int22_ar[A][U][U][A][G][U][U][G] = 2.400;
+ int22_ar[A][U][U][A][U][A][U][G] = 2.000;
+ int22_ar[A][U][U][A][U][C][U][G] = 2.000;
+ int22_ar[A][U][U][A][U][G][U][G] = 2.000;
+ int22_ar[A][U][U][A][U][U][U][G] = 2.000;
+ int22_ar[A][U][U][C][A][A][U][G] = 2.000;
+ int22_ar[A][U][U][C][A][C][U][G] = 2.500;
+ int22_ar[A][U][U][C][A][G][U][G] = 0.300;
+ int22_ar[A][U][U][C][A][U][U][G] = 1.700;
+ int22_ar[A][U][U][C][C][A][U][G] = 2.000;
+ int22_ar[A][U][U][C][C][C][U][G] = 2.500;
+ int22_ar[A][U][U][C][C][G][U][G] = 1.300;
+ int22_ar[A][U][U][C][C][U][U][G] = 1.700;
+ int22_ar[A][U][U][C][G][A][U][G] = 2.000;
+ int22_ar[A][U][U][C][G][C][U][G] = 2.000;
+ int22_ar[A][U][U][C][G][G][U][G] = 2.000;
+ int22_ar[A][U][U][C][G][U][U][G] = 2.000;
+ int22_ar[A][U][U][C][U][A][U][G] = 2.000;
+ int22_ar[A][U][U][C][U][C][U][G] = 2.500;
+ int22_ar[A][U][U][C][U][G][U][G] = 1.300;
+ int22_ar[A][U][U][C][U][U][U][G] = 1.700;
+ int22_ar[A][U][U][G][A][A][U][G] = 2.000;
+ int22_ar[A][U][U][G][A][C][U][G] = 2.400;
+ int22_ar[A][U][U][G][A][G][U][G] = 1.100;
+ int22_ar[A][U][U][G][A][U][U][G] = 2.400;
+ int22_ar[A][U][U][G][C][A][U][G] = 2.000;
+ int22_ar[A][U][U][G][C][C][U][G] = 2.000;
+ int22_ar[A][U][U][G][C][G][U][G] = 2.000;
+ int22_ar[A][U][U][G][C][U][U][G] = 2.000;
+ int22_ar[A][U][U][G][G][A][U][G] = 2.000;
+ int22_ar[A][U][U][G][G][C][U][G] = 2.400;
+ int22_ar[A][U][U][G][G][G][U][G] = 0.700;
+ int22_ar[A][U][U][G][G][U][U][G] = 2.000;
+ int22_ar[A][U][U][G][U][A][U][G] = 2.000;
+ int22_ar[A][U][U][G][U][C][U][G] = 0.700;
+ int22_ar[A][U][U][G][U][G][U][G] = -2.500;
+ int22_ar[A][U][U][G][U][U][U][G] = 0.700;
+ int22_ar[A][U][U][U][A][A][U][G] = 2.000;
+ int22_ar[A][U][U][U][A][C][U][G] = 2.000;
+ int22_ar[A][U][U][U][A][G][U][G] = 2.000;
+ int22_ar[A][U][U][U][A][U][U][G] = 2.000;
+ int22_ar[A][U][U][U][C][A][U][G] = 2.000;
+ int22_ar[A][U][U][U][C][C][U][G] = 2.200;
+ int22_ar[A][U][U][U][C][G][U][G] = 1.000;
+ int22_ar[A][U][U][U][C][U][U][G] = 1.400;
+ int22_ar[A][U][U][U][G][A][U][G] = 2.000;
+ int22_ar[A][U][U][U][G][C][U][G] = 1.900;
+ int22_ar[A][U][U][U][G][G][U][G] = -1.200;
+ int22_ar[A][U][U][U][G][U][U][G] = 1.900;
+ int22_ar[A][U][U][U][U][A][U][G] = 2.000;
+ int22_ar[A][U][U][U][U][C][U][G] = 1.600;
+ int22_ar[A][U][U][U][U][G][U][G] = 1.300;
+ int22_ar[A][U][U][U][U][U][U][G] = 0.800;
+ int22_ar[C][G][A][A][A][A][A][U] = 2.000;
+ int22_ar[C][G][A][A][A][C][A][U] = 2.400;
+ int22_ar[C][G][A][A][A][G][A][U] = 1.000;
+ int22_ar[C][G][A][A][A][U][A][U] = 2.000;
+ int22_ar[C][G][A][A][C][A][A][U] = 1.800;
+ int22_ar[C][G][A][A][C][C][A][U] = 2.100;
+ int22_ar[C][G][A][A][C][G][A][U] = 0.800;
+ int22_ar[C][G][A][A][C][U][A][U] = 2.000;
+ int22_ar[C][G][A][A][G][A][A][U] = 0.800;
+ int22_ar[C][G][A][A][G][C][A][U] = 1.100;
+ int22_ar[C][G][A][A][G][G][A][U] = -0.200;
+ int22_ar[C][G][A][A][G][U][A][U] = 2.000;
+ int22_ar[C][G][A][A][U][A][A][U] = 2.000;
+ int22_ar[C][G][A][A][U][C][A][U] = 2.000;
+ int22_ar[C][G][A][A][U][G][A][U] = 2.000;
+ int22_ar[C][G][A][A][U][U][A][U] = 2.000;
+ int22_ar[C][G][A][C][A][A][A][U] = 1.900;
+ int22_ar[C][G][A][C][A][C][A][U] = 2.200;
+ int22_ar[C][G][A][C][A][G][A][U] = 0.900;
+ int22_ar[C][G][A][C][A][U][A][U] = 2.000;
+ int22_ar[C][G][A][C][C][A][A][U] = 2.300;
+ int22_ar[C][G][A][C][C][C][A][U] = 2.100;
+ int22_ar[C][G][A][C][C][G][A][U] = 1.700;
+ int22_ar[C][G][A][C][C][U][A][U] = 2.000;
+ int22_ar[C][G][A][C][G][A][A][U] = 2.000;
+ int22_ar[C][G][A][C][G][C][A][U] = 2.000;
+ int22_ar[C][G][A][C][G][G][A][U] = 2.000;
+ int22_ar[C][G][A][C][G][U][A][U] = 2.000;
+ int22_ar[C][G][A][C][U][A][A][U] = 2.300;
+ int22_ar[C][G][A][C][U][C][A][U] = 2.100;
+ int22_ar[C][G][A][C][U][G][A][U] = 1.700;
+ int22_ar[C][G][A][C][U][U][A][U] = 2.000;
+ int22_ar[C][G][A][G][A][A][A][U] = 0.800;
+ int22_ar[C][G][A][G][A][C][A][U] = 1.100;
+ int22_ar[C][G][A][G][A][G][A][U] = -0.200;
+ int22_ar[C][G][A][G][A][U][A][U] = 2.000;
+ int22_ar[C][G][A][G][C][A][A][U] = 2.000;
+ int22_ar[C][G][A][G][C][C][A][U] = 2.000;
+ int22_ar[C][G][A][G][C][G][A][U] = 2.000;
+ int22_ar[C][G][A][G][C][U][A][U] = 2.000;
+ int22_ar[C][G][A][G][G][A][A][U] = 1.300;
+ int22_ar[C][G][A][G][G][C][A][U] = 1.700;
+ int22_ar[C][G][A][G][G][G][A][U] = 0.300;
+ int22_ar[C][G][A][G][G][U][A][U] = 2.000;
+ int22_ar[C][G][A][G][U][A][A][U] = 0.600;
+ int22_ar[C][G][A][G][U][C][A][U] = 0.000;
+ int22_ar[C][G][A][G][U][G][A][U] = 0.400;
+ int22_ar[C][G][A][G][U][U][A][U] = 2.000;
+ int22_ar[C][G][A][U][A][A][A][U] = 2.000;
+ int22_ar[C][G][A][U][A][C][A][U] = 2.000;
+ int22_ar[C][G][A][U][A][G][A][U] = 2.000;
+ int22_ar[C][G][A][U][A][U][A][U] = 2.000;
+ int22_ar[C][G][A][U][C][A][A][U] = 2.300;
+ int22_ar[C][G][A][U][C][C][A][U] = 2.100;
+ int22_ar[C][G][A][U][C][G][A][U] = 1.700;
+ int22_ar[C][G][A][U][C][U][A][U] = 2.000;
+ int22_ar[C][G][A][U][G][A][A][U] = 1.600;
+ int22_ar[C][G][A][U][G][C][A][U] = 0.900;
+ int22_ar[C][G][A][U][G][G][A][U] = 1.400;
+ int22_ar[C][G][A][U][G][U][A][U] = 2.000;
+ int22_ar[C][G][A][U][U][A][A][U] = 1.900;
+ int22_ar[C][G][A][U][U][C][A][U] = 1.300;
+ int22_ar[C][G][A][U][U][G][A][U] = 1.800;
+ int22_ar[C][G][A][U][U][U][A][U] = 2.000;
+ int22_ar[C][G][C][A][A][A][A][U] = 1.900;
+ int22_ar[C][G][C][A][A][C][A][U] = 2.800;
+ int22_ar[C][G][C][A][A][G][A][U] = 2.000;
+ int22_ar[C][G][C][A][A][U][A][U] = 2.700;
+ int22_ar[C][G][C][A][C][A][A][U] = 1.700;
+ int22_ar[C][G][C][A][C][C][A][U] = 2.000;
+ int22_ar[C][G][C][A][C][G][A][U] = 2.000;
+ int22_ar[C][G][C][A][C][U][A][U] = 1.800;
+ int22_ar[C][G][C][A][G][A][A][U] = 0.700;
+ int22_ar[C][G][C][A][G][C][A][U] = 2.000;
+ int22_ar[C][G][C][A][G][G][A][U] = 2.000;
+ int22_ar[C][G][C][A][G][U][A][U] = 1.800;
+ int22_ar[C][G][C][A][U][A][A][U] = 2.000;
+ int22_ar[C][G][C][A][U][C][A][U] = 2.000;
+ int22_ar[C][G][C][A][U][G][A][U] = 2.000;
+ int22_ar[C][G][C][A][U][U][A][U] = 2.000;
+ int22_ar[C][G][C][C][A][A][A][U] = 1.800;
+ int22_ar[C][G][C][C][A][C][A][U] = 2.100;
+ int22_ar[C][G][C][C][A][G][A][U] = 2.000;
+ int22_ar[C][G][C][C][A][U][A][U] = 1.900;
+ int22_ar[C][G][C][C][C][A][A][U] = 1.600;
+ int22_ar[C][G][C][C][C][C][A][U] = 1.900;
+ int22_ar[C][G][C][C][C][G][A][U] = 2.000;
+ int22_ar[C][G][C][C][C][U][A][U] = 1.800;
+ int22_ar[C][G][C][C][G][A][A][U] = 2.000;
+ int22_ar[C][G][C][C][G][C][A][U] = 2.000;
+ int22_ar[C][G][C][C][G][G][A][U] = 2.000;
+ int22_ar[C][G][C][C][G][U][A][U] = 2.000;
+ int22_ar[C][G][C][C][U][A][A][U] = 1.600;
+ int22_ar[C][G][C][C][U][C][A][U] = 1.900;
+ int22_ar[C][G][C][C][U][G][A][U] = 2.000;
+ int22_ar[C][G][C][C][U][U][A][U] = 1.800;
+ int22_ar[C][G][C][G][A][A][A][U] = 0.700;
+ int22_ar[C][G][C][G][A][C][A][U] = 2.000;
+ int22_ar[C][G][C][G][A][G][A][U] = 2.000;
+ int22_ar[C][G][C][G][A][U][A][U] = 1.800;
+ int22_ar[C][G][C][G][C][A][A][U] = 2.000;
+ int22_ar[C][G][C][G][C][C][A][U] = 2.000;
+ int22_ar[C][G][C][G][C][G][A][U] = 2.000;
+ int22_ar[C][G][C][G][C][U][A][U] = 2.000;
+ int22_ar[C][G][C][G][G][A][A][U] = 1.200;
+ int22_ar[C][G][C][G][G][C][A][U] = 2.100;
+ int22_ar[C][G][C][G][G][G][A][U] = 2.000;
+ int22_ar[C][G][C][G][G][U][A][U] = 2.000;
+ int22_ar[C][G][C][G][U][A][A][U] = -0.500;
+ int22_ar[C][G][C][G][U][C][A][U] = 0.800;
+ int22_ar[C][G][C][G][U][G][A][U] = 2.000;
+ int22_ar[C][G][C][G][U][U][A][U] = 0.700;
+ int22_ar[C][G][C][U][A][A][A][U] = 2.000;
+ int22_ar[C][G][C][U][A][C][A][U] = 2.000;
+ int22_ar[C][G][C][U][A][G][A][U] = 2.000;
+ int22_ar[C][G][C][U][A][U][A][U] = 2.000;
+ int22_ar[C][G][C][U][C][A][A][U] = 1.600;
+ int22_ar[C][G][C][U][C][C][A][U] = 1.900;
+ int22_ar[C][G][C][U][C][G][A][U] = 2.000;
+ int22_ar[C][G][C][U][C][U][A][U] = 1.800;
+ int22_ar[C][G][C][U][G][A][A][U] = 0.500;
+ int22_ar[C][G][C][U][G][C][A][U] = 1.800;
+ int22_ar[C][G][C][U][G][G][A][U] = 2.000;
+ int22_ar[C][G][C][U][G][U][A][U] = 1.600;
+ int22_ar[C][G][C][U][U][A][A][U] = 0.800;
+ int22_ar[C][G][C][U][U][C][A][U] = 1.100;
+ int22_ar[C][G][C][U][U][G][A][U] = 2.000;
+ int22_ar[C][G][C][U][U][U][A][U] = 1.000;
+ int22_ar[C][G][G][A][A][A][A][U] = 1.000;
+ int22_ar[C][G][G][A][A][C][A][U] = 2.000;
+ int22_ar[C][G][G][A][A][G][A][U] = 1.800;
+ int22_ar[C][G][G][A][A][U][A][U] = 1.800;
+ int22_ar[C][G][G][A][C][A][A][U] = 0.800;
+ int22_ar[C][G][G][A][C][C][A][U] = 2.000;
+ int22_ar[C][G][G][A][C][G][A][U] = 1.500;
+ int22_ar[C][G][G][A][C][U][A][U] = 0.600;
+ int22_ar[C][G][G][A][G][A][A][U] = -0.200;
+ int22_ar[C][G][G][A][G][C][A][U] = 2.000;
+ int22_ar[C][G][G][A][G][G][A][U] = 0.500;
+ int22_ar[C][G][G][A][G][U][A][U] = 1.400;
+ int22_ar[C][G][G][A][U][A][A][U] = 2.000;
+ int22_ar[C][G][G][A][U][C][A][U] = 2.000;
+ int22_ar[C][G][G][A][U][G][A][U] = 2.000;
+ int22_ar[C][G][G][A][U][U][A][U] = 2.000;
+ int22_ar[C][G][G][C][A][A][A][U] = 0.900;
+ int22_ar[C][G][G][C][A][C][A][U] = 2.000;
+ int22_ar[C][G][G][C][A][G][A][U] = 1.600;
+ int22_ar[C][G][G][C][A][U][A][U] = 0.700;
+ int22_ar[C][G][G][C][C][A][A][U] = 1.700;
+ int22_ar[C][G][G][C][C][C][A][U] = 2.000;
+ int22_ar[C][G][G][C][C][G][A][U] = 2.100;
+ int22_ar[C][G][G][C][C][U][A][U] = 1.500;
+ int22_ar[C][G][G][C][G][A][A][U] = 2.000;
+ int22_ar[C][G][G][C][G][C][A][U] = 2.000;
+ int22_ar[C][G][G][C][G][G][A][U] = 2.000;
+ int22_ar[C][G][G][C][G][U][A][U] = 2.000;
+ int22_ar[C][G][G][C][U][A][A][U] = 1.700;
+ int22_ar[C][G][G][C][U][C][A][U] = 2.000;
+ int22_ar[C][G][G][C][U][G][A][U] = 2.100;
+ int22_ar[C][G][G][C][U][U][A][U] = 1.500;
+ int22_ar[C][G][G][G][A][A][A][U] = -0.200;
+ int22_ar[C][G][G][G][A][C][A][U] = 2.000;
+ int22_ar[C][G][G][G][A][G][A][U] = 0.500;
+ int22_ar[C][G][G][G][A][U][A][U] = 1.400;
+ int22_ar[C][G][G][G][C][A][A][U] = 2.000;
+ int22_ar[C][G][G][G][C][C][A][U] = 2.000;
+ int22_ar[C][G][G][G][C][G][A][U] = 2.000;
+ int22_ar[C][G][G][G][C][U][A][U] = 2.000;
+ int22_ar[C][G][G][G][G][A][A][U] = 0.300;
+ int22_ar[C][G][G][G][G][C][A][U] = 2.000;
+ int22_ar[C][G][G][G][G][G][A][U] = 1.100;
+ int22_ar[C][G][G][G][G][U][A][U] = 1.100;
+ int22_ar[C][G][G][G][U][A][A][U] = 0.400;
+ int22_ar[C][G][G][G][U][C][A][U] = 2.000;
+ int22_ar[C][G][G][G][U][G][A][U] = 0.400;
+ int22_ar[C][G][G][G][U][U][A][U] = -1.600;
+ int22_ar[C][G][G][U][A][A][A][U] = 2.000;
+ int22_ar[C][G][G][U][A][C][A][U] = 2.000;
+ int22_ar[C][G][G][U][A][G][A][U] = 2.000;
+ int22_ar[C][G][G][U][A][U][A][U] = 2.000;
+ int22_ar[C][G][G][U][C][A][A][U] = 1.700;
+ int22_ar[C][G][G][U][C][C][A][U] = 2.000;
+ int22_ar[C][G][G][U][C][G][A][U] = 2.100;
+ int22_ar[C][G][G][U][C][U][A][U] = 1.500;
+ int22_ar[C][G][G][U][G][A][A][U] = 1.400;
+ int22_ar[C][G][G][U][G][C][A][U] = 2.000;
+ int22_ar[C][G][G][U][G][G][A][U] = 1.300;
+ int22_ar[C][G][G][U][G][U][A][U] = -0.600;
+ int22_ar[C][G][G][U][U][A][A][U] = 1.800;
+ int22_ar[C][G][G][U][U][C][A][U] = 2.000;
+ int22_ar[C][G][G][U][U][G][A][U] = 1.700;
+ int22_ar[C][G][G][U][U][U][A][U] = 1.600;
+ int22_ar[C][G][U][A][A][A][A][U] = 2.000;
+ int22_ar[C][G][U][A][A][C][A][U] = 2.700;
+ int22_ar[C][G][U][A][A][G][A][U] = 0.300;
+ int22_ar[C][G][U][A][A][U][A][U] = 2.200;
+ int22_ar[C][G][U][A][C][A][A][U] = 2.000;
+ int22_ar[C][G][U][A][C][C][A][U] = 1.800;
+ int22_ar[C][G][U][A][C][G][A][U] = -0.900;
+ int22_ar[C][G][U][A][C][U][A][U] = 0.900;
+ int22_ar[C][G][U][A][G][A][A][U] = 2.000;
+ int22_ar[C][G][U][A][G][C][A][U] = 1.800;
+ int22_ar[C][G][U][A][G][G][A][U] = -0.100;
+ int22_ar[C][G][U][A][G][U][A][U] = 1.800;
+ int22_ar[C][G][U][A][U][A][A][U] = 2.000;
+ int22_ar[C][G][U][A][U][C][A][U] = 2.000;
+ int22_ar[C][G][U][A][U][G][A][U] = 2.000;
+ int22_ar[C][G][U][A][U][U][A][U] = 2.000;
+ int22_ar[C][G][U][C][A][A][A][U] = 2.000;
+ int22_ar[C][G][U][C][A][C][A][U] = 1.900;
+ int22_ar[C][G][U][C][A][G][A][U] = -0.800;
+ int22_ar[C][G][U][C][A][U][A][U] = 1.000;
+ int22_ar[C][G][U][C][C][A][A][U] = 2.000;
+ int22_ar[C][G][U][C][C][C][A][U] = 1.800;
+ int22_ar[C][G][U][C][C][G][A][U] = 0.000;
+ int22_ar[C][G][U][C][C][U][A][U] = 0.900;
+ int22_ar[C][G][U][C][G][A][A][U] = 2.000;
+ int22_ar[C][G][U][C][G][C][A][U] = 2.000;
+ int22_ar[C][G][U][C][G][G][A][U] = 2.000;
+ int22_ar[C][G][U][C][G][U][A][U] = 2.000;
+ int22_ar[C][G][U][C][U][A][A][U] = 2.000;
+ int22_ar[C][G][U][C][U][C][A][U] = 1.800;
+ int22_ar[C][G][U][C][U][G][A][U] = 0.000;
+ int22_ar[C][G][U][C][U][U][A][U] = 0.900;
+ int22_ar[C][G][U][G][A][A][A][U] = 2.000;
+ int22_ar[C][G][U][G][A][C][A][U] = 1.800;
+ int22_ar[C][G][U][G][A][G][A][U] = -0.100;
+ int22_ar[C][G][U][G][A][U][A][U] = 1.800;
+ int22_ar[C][G][U][G][C][A][A][U] = 2.000;
+ int22_ar[C][G][U][G][C][C][A][U] = 2.000;
+ int22_ar[C][G][U][G][C][G][A][U] = 2.000;
+ int22_ar[C][G][U][G][C][U][A][U] = 2.000;
+ int22_ar[C][G][U][G][G][A][A][U] = 2.000;
+ int22_ar[C][G][U][G][G][C][A][U] = 2.000;
+ int22_ar[C][G][U][G][G][G][A][U] = -0.400;
+ int22_ar[C][G][U][G][G][U][A][U] = 1.500;
+ int22_ar[C][G][U][G][U][A][A][U] = 2.000;
+ int22_ar[C][G][U][G][U][C][A][U] = 0.700;
+ int22_ar[C][G][U][G][U][G][A][U] = -3.100;
+ int22_ar[C][G][U][G][U][U][A][U] = 0.600;
+ int22_ar[C][G][U][U][A][A][A][U] = 2.000;
+ int22_ar[C][G][U][U][A][C][A][U] = 2.000;
+ int22_ar[C][G][U][U][A][G][A][U] = 2.000;
+ int22_ar[C][G][U][U][A][U][A][U] = 2.000;
+ int22_ar[C][G][U][U][C][A][A][U] = 2.000;
+ int22_ar[C][G][U][U][C][C][A][U] = 1.800;
+ int22_ar[C][G][U][U][C][G][A][U] = 0.000;
+ int22_ar[C][G][U][U][C][U][A][U] = 0.900;
+ int22_ar[C][G][U][U][G][A][A][U] = 2.000;
+ int22_ar[C][G][U][U][G][C][A][U] = 1.600;
+ int22_ar[C][G][U][U][G][G][A][U] = -2.100;
+ int22_ar[C][G][U][U][G][U][A][U] = 1.600;
+ int22_ar[C][G][U][U][U][A][A][U] = 2.000;
+ int22_ar[C][G][U][U][U][C][A][U] = 1.000;
+ int22_ar[C][G][U][U][U][G][A][U] = 0.000;
+ int22_ar[C][G][U][U][U][U][A][U] = 0.100;
+ int22_ar[C][G][A][A][A][A][C][G] = 1.300;
+ int22_ar[C][G][A][A][A][C][C][G] = 1.600;
+ int22_ar[C][G][A][A][A][G][C][G] = 0.300;
+ int22_ar[C][G][A][A][A][U][C][G] = 2.000;
+ int22_ar[C][G][A][A][C][A][C][G] = 1.200;
+ int22_ar[C][G][A][A][C][C][C][G] = 1.500;
+ int22_ar[C][G][A][A][C][G][C][G] = 0.200;
+ int22_ar[C][G][A][A][C][U][C][G] = 2.000;
+ int22_ar[C][G][A][A][G][A][C][G] = 0.300;
+ int22_ar[C][G][A][A][G][C][C][G] = 0.600;
+ int22_ar[C][G][A][A][G][G][C][G] = -0.700;
+ int22_ar[C][G][A][A][G][U][C][G] = 2.000;
+ int22_ar[C][G][A][A][U][A][C][G] = 2.000;
+ int22_ar[C][G][A][A][U][C][C][G] = 2.000;
+ int22_ar[C][G][A][A][U][G][C][G] = 2.000;
+ int22_ar[C][G][A][A][U][U][C][G] = 2.000;
+ int22_ar[C][G][A][C][A][A][C][G] = 1.600;
+ int22_ar[C][G][A][C][A][C][C][G] = 2.000;
+ int22_ar[C][G][A][C][A][G][C][G] = 0.600;
+ int22_ar[C][G][A][C][A][U][C][G] = 2.000;
+ int22_ar[C][G][A][C][C][A][C][G] = 2.100;
+ int22_ar[C][G][A][C][C][C][C][G] = 1.800;
+ int22_ar[C][G][A][C][C][G][C][G] = 1.500;
+ int22_ar[C][G][A][C][C][U][C][G] = 2.000;
+ int22_ar[C][G][A][C][G][A][C][G] = 2.000;
+ int22_ar[C][G][A][C][G][C][C][G] = 2.000;
+ int22_ar[C][G][A][C][G][G][C][G] = 2.000;
+ int22_ar[C][G][A][C][G][U][C][G] = 2.000;
+ int22_ar[C][G][A][C][U][A][C][G] = 1.900;
+ int22_ar[C][G][A][C][U][C][C][G] = 1.700;
+ int22_ar[C][G][A][C][U][G][C][G] = 1.300;
+ int22_ar[C][G][A][C][U][U][C][G] = 2.000;
+ int22_ar[C][G][A][G][A][A][C][G] = 0.300;
+ int22_ar[C][G][A][G][A][C][C][G] = 0.600;
+ int22_ar[C][G][A][G][A][G][C][G] = -0.700;
+ int22_ar[C][G][A][G][A][U][C][G] = 2.000;
+ int22_ar[C][G][A][G][C][A][C][G] = 2.000;
+ int22_ar[C][G][A][G][C][C][C][G] = 2.000;
+ int22_ar[C][G][A][G][C][G][C][G] = 2.000;
+ int22_ar[C][G][A][G][C][U][C][G] = 2.000;
+ int22_ar[C][G][A][G][G][A][C][G] = 1.000;
+ int22_ar[C][G][A][G][G][C][C][G] = 1.400;
+ int22_ar[C][G][A][G][G][G][C][G] = 0.000;
+ int22_ar[C][G][A][G][G][U][C][G] = 2.000;
+ int22_ar[C][G][A][G][U][A][C][G] = -0.400;
+ int22_ar[C][G][A][G][U][C][C][G] = -1.100;
+ int22_ar[C][G][A][G][U][G][C][G] = -0.600;
+ int22_ar[C][G][A][G][U][U][C][G] = 2.000;
+ int22_ar[C][G][A][U][A][A][C][G] = 2.000;
+ int22_ar[C][G][A][U][A][C][C][G] = 2.000;
+ int22_ar[C][G][A][U][A][G][C][G] = 2.000;
+ int22_ar[C][G][A][U][A][U][C][G] = 2.000;
+ int22_ar[C][G][A][U][C][A][C][G] = 1.900;
+ int22_ar[C][G][A][U][C][C][C][G] = 1.700;
+ int22_ar[C][G][A][U][C][G][C][G] = 1.300;
+ int22_ar[C][G][A][U][C][U][C][G] = 2.000;
+ int22_ar[C][G][A][U][G][A][C][G] = 1.100;
+ int22_ar[C][G][A][U][G][C][C][G] = 0.400;
+ int22_ar[C][G][A][U][G][G][C][G] = 0.900;
+ int22_ar[C][G][A][U][G][U][C][G] = 2.000;
+ int22_ar[C][G][A][U][U][A][C][G] = 1.400;
+ int22_ar[C][G][A][U][U][C][C][G] = 0.800;
+ int22_ar[C][G][A][U][U][G][C][G] = 1.300;
+ int22_ar[C][G][A][U][U][U][C][G] = 2.000;
+ int22_ar[C][G][C][A][A][A][C][G] = 1.200;
+ int22_ar[C][G][C][A][A][C][C][G] = 2.100;
+ int22_ar[C][G][C][A][A][G][C][G] = 2.000;
+ int22_ar[C][G][C][A][A][U][C][G] = 1.900;
+ int22_ar[C][G][C][A][C][A][C][G] = 1.100;
+ int22_ar[C][G][C][A][C][C][C][G] = 1.400;
+ int22_ar[C][G][C][A][C][G][C][G] = 2.000;
+ int22_ar[C][G][C][A][C][U][C][G] = 1.200;
+ int22_ar[C][G][C][A][G][A][C][G] = 0.200;
+ int22_ar[C][G][C][A][G][C][C][G] = 1.500;
+ int22_ar[C][G][C][A][G][G][C][G] = 2.000;
+ int22_ar[C][G][C][A][G][U][C][G] = 1.300;
+ int22_ar[C][G][C][A][U][A][C][G] = 2.000;
+ int22_ar[C][G][C][A][U][C][C][G] = 2.000;
+ int22_ar[C][G][C][A][U][G][C][G] = 2.000;
+ int22_ar[C][G][C][A][U][U][C][G] = 2.000;
+ int22_ar[C][G][C][C][A][A][C][G] = 1.500;
+ int22_ar[C][G][C][C][A][C][C][G] = 1.800;
+ int22_ar[C][G][C][C][A][G][C][G] = 2.000;
+ int22_ar[C][G][C][C][A][U][C][G] = 1.700;
+ int22_ar[C][G][C][C][C][A][C][G] = 1.400;
+ int22_ar[C][G][C][C][C][C][C][G] = 1.700;
+ int22_ar[C][G][C][C][C][G][C][G] = 2.000;
+ int22_ar[C][G][C][C][C][U][C][G] = 1.500;
+ int22_ar[C][G][C][C][G][A][C][G] = 2.000;
+ int22_ar[C][G][C][C][G][C][C][G] = 2.000;
+ int22_ar[C][G][C][C][G][G][C][G] = 2.000;
+ int22_ar[C][G][C][C][G][U][C][G] = 2.000;
+ int22_ar[C][G][C][C][U][A][C][G] = 1.200;
+ int22_ar[C][G][C][C][U][C][C][G] = 1.500;
+ int22_ar[C][G][C][C][U][G][C][G] = 2.000;
+ int22_ar[C][G][C][C][U][U][C][G] = 1.400;
+ int22_ar[C][G][C][G][A][A][C][G] = 0.200;
+ int22_ar[C][G][C][G][A][C][C][G] = 1.500;
+ int22_ar[C][G][C][G][A][G][C][G] = 2.000;
+ int22_ar[C][G][C][G][A][U][C][G] = 1.300;
+ int22_ar[C][G][C][G][C][A][C][G] = 2.000;
+ int22_ar[C][G][C][G][C][C][C][G] = 2.000;
+ int22_ar[C][G][C][G][C][G][C][G] = 2.000;
+ int22_ar[C][G][C][G][C][U][C][G] = 2.000;
+ int22_ar[C][G][C][G][G][A][C][G] = 0.900;
+ int22_ar[C][G][C][G][G][C][C][G] = 1.800;
+ int22_ar[C][G][C][G][G][G][C][G] = 2.000;
+ int22_ar[C][G][C][G][G][U][C][G] = 1.700;
+ int22_ar[C][G][C][G][U][A][C][G] = -1.500;
+ int22_ar[C][G][C][G][U][C][C][G] = -0.200;
+ int22_ar[C][G][C][G][U][G][C][G] = 2.000;
+ int22_ar[C][G][C][G][U][U][C][G] = -0.400;
+ int22_ar[C][G][C][U][A][A][C][G] = 2.000;
+ int22_ar[C][G][C][U][A][C][C][G] = 2.000;
+ int22_ar[C][G][C][U][A][G][C][G] = 2.000;
+ int22_ar[C][G][C][U][A][U][C][G] = 2.000;
+ int22_ar[C][G][C][U][C][A][C][G] = 1.200;
+ int22_ar[C][G][C][U][C][C][C][G] = 1.500;
+ int22_ar[C][G][C][U][C][G][C][G] = 2.000;
+ int22_ar[C][G][C][U][C][U][C][G] = 1.400;
+ int22_ar[C][G][C][U][G][A][C][G] = 0.000;
+ int22_ar[C][G][C][U][G][C][C][G] = 1.300;
+ int22_ar[C][G][C][U][G][G][C][G] = 2.000;
+ int22_ar[C][G][C][U][G][U][C][G] = 1.100;
+ int22_ar[C][G][C][U][U][A][C][G] = 0.300;
+ int22_ar[C][G][C][U][U][C][C][G] = 0.600;
+ int22_ar[C][G][C][U][U][G][C][G] = 2.000;
+ int22_ar[C][G][C][U][U][U][C][G] = 0.500;
+ int22_ar[C][G][G][A][A][A][C][G] = 0.300;
+ int22_ar[C][G][G][A][A][C][C][G] = 2.000;
+ int22_ar[C][G][G][A][A][G][C][G] = 1.000;
+ int22_ar[C][G][G][A][A][U][C][G] = 1.100;
+ int22_ar[C][G][G][A][C][A][C][G] = 0.200;
+ int22_ar[C][G][G][A][C][C][C][G] = 2.000;
+ int22_ar[C][G][G][A][C][G][C][G] = 0.900;
+ int22_ar[C][G][G][A][C][U][C][G] = 0.000;
+ int22_ar[C][G][G][A][G][A][C][G] = -0.700;
+ int22_ar[C][G][G][A][G][C][C][G] = 2.000;
+ int22_ar[C][G][G][A][G][G][C][G] = 0.000;
+ int22_ar[C][G][G][A][G][U][C][G] = 0.900;
+ int22_ar[C][G][G][A][U][A][C][G] = 2.000;
+ int22_ar[C][G][G][A][U][C][C][G] = 2.000;
+ int22_ar[C][G][G][A][U][G][C][G] = 2.000;
+ int22_ar[C][G][G][A][U][U][C][G] = 2.000;
+ int22_ar[C][G][G][C][A][A][C][G] = 0.600;
+ int22_ar[C][G][G][C][A][C][C][G] = 2.000;
+ int22_ar[C][G][G][C][A][G][C][G] = 1.400;
+ int22_ar[C][G][G][C][A][U][C][G] = 0.400;
+ int22_ar[C][G][G][C][C][A][C][G] = 1.500;
+ int22_ar[C][G][G][C][C][C][C][G] = 2.000;
+ int22_ar[C][G][G][C][C][G][C][G] = 1.800;
+ int22_ar[C][G][G][C][C][U][C][G] = 1.300;
+ int22_ar[C][G][G][C][G][A][C][G] = 2.000;
+ int22_ar[C][G][G][C][G][C][C][G] = 2.000;
+ int22_ar[C][G][G][C][G][G][C][G] = 2.000;
+ int22_ar[C][G][G][C][G][U][C][G] = 2.000;
+ int22_ar[C][G][G][C][U][A][C][G] = 1.300;
+ int22_ar[C][G][G][C][U][C][C][G] = 2.000;
+ int22_ar[C][G][G][C][U][G][C][G] = 1.700;
+ int22_ar[C][G][G][C][U][U][C][G] = 1.100;
+ int22_ar[C][G][G][G][A][A][C][G] = -0.700;
+ int22_ar[C][G][G][G][A][C][C][G] = 2.000;
+ int22_ar[C][G][G][G][A][G][C][G] = 0.000;
+ int22_ar[C][G][G][G][A][U][C][G] = 0.900;
+ int22_ar[C][G][G][G][C][A][C][G] = 2.000;
+ int22_ar[C][G][G][G][C][C][C][G] = 2.000;
+ int22_ar[C][G][G][G][C][G][C][G] = 2.000;
+ int22_ar[C][G][G][G][C][U][C][G] = 2.000;
+ int22_ar[C][G][G][G][G][A][C][G] = 0.000;
+ int22_ar[C][G][G][G][G][C][C][G] = 2.000;
+ int22_ar[C][G][G][G][G][G][C][G] = 0.800;
+ int22_ar[C][G][G][G][G][U][C][G] = 0.900;
+ int22_ar[C][G][G][G][U][A][C][G] = -0.600;
+ int22_ar[C][G][G][G][U][C][C][G] = 2.000;
+ int22_ar[C][G][G][G][U][G][C][G] = -0.700;
+ int22_ar[C][G][G][G][U][U][C][G] = -2.600;
+ int22_ar[C][G][G][U][A][A][C][G] = 2.000;
+ int22_ar[C][G][G][U][A][C][C][G] = 2.000;
+ int22_ar[C][G][G][U][A][G][C][G] = 2.000;
+ int22_ar[C][G][G][U][A][U][C][G] = 2.000;
+ int22_ar[C][G][G][U][C][A][C][G] = 1.300;
+ int22_ar[C][G][G][U][C][C][C][G] = 2.000;
+ int22_ar[C][G][G][U][C][G][C][G] = 1.700;
+ int22_ar[C][G][G][U][C][U][C][G] = 1.100;
+ int22_ar[C][G][G][U][G][A][C][G] = 0.900;
+ int22_ar[C][G][G][U][G][C][C][G] = 2.000;
+ int22_ar[C][G][G][U][G][G][C][G] = 0.900;
+ int22_ar[C][G][G][U][G][U][C][G] = -1.100;
+ int22_ar[C][G][G][U][U][A][C][G] = 1.300;
+ int22_ar[C][G][G][U][U][C][C][G] = 2.000;
+ int22_ar[C][G][G][U][U][G][C][G] = 1.200;
+ int22_ar[C][G][G][U][U][U][C][G] = 1.100;
+ int22_ar[C][G][U][A][A][A][C][G] = 2.000;
+ int22_ar[C][G][U][A][A][C][C][G] = 1.900;
+ int22_ar[C][G][U][A][A][G][C][G] = -0.400;
+ int22_ar[C][G][U][A][A][U][C][G] = 1.400;
+ int22_ar[C][G][U][A][C][A][C][G] = 2.000;
+ int22_ar[C][G][U][A][C][C][C][G] = 1.200;
+ int22_ar[C][G][U][A][C][G][C][G] = -1.500;
+ int22_ar[C][G][U][A][C][U][C][G] = 0.300;
+ int22_ar[C][G][U][A][G][A][C][G] = 2.000;
+ int22_ar[C][G][U][A][G][C][C][G] = 1.300;
+ int22_ar[C][G][U][A][G][G][C][G] = -0.600;
+ int22_ar[C][G][U][A][G][U][C][G] = 1.300;
+ int22_ar[C][G][U][A][U][A][C][G] = 2.000;
+ int22_ar[C][G][U][A][U][C][C][G] = 2.000;
+ int22_ar[C][G][U][A][U][G][C][G] = 2.000;
+ int22_ar[C][G][U][A][U][U][C][G] = 2.000;
+ int22_ar[C][G][U][C][A][A][C][G] = 2.000;
+ int22_ar[C][G][U][C][A][C][C][G] = 1.700;
+ int22_ar[C][G][U][C][A][G][C][G] = -1.100;
+ int22_ar[C][G][U][C][A][U][C][G] = 0.800;
+ int22_ar[C][G][U][C][C][A][C][G] = 2.000;
+ int22_ar[C][G][U][C][C][C][C][G] = 1.500;
+ int22_ar[C][G][U][C][C][G][C][G] = -0.200;
+ int22_ar[C][G][U][C][C][U][C][G] = 0.600;
+ int22_ar[C][G][U][C][G][A][C][G] = 2.000;
+ int22_ar[C][G][U][C][G][C][C][G] = 2.000;
+ int22_ar[C][G][U][C][G][G][C][G] = 2.000;
+ int22_ar[C][G][U][C][G][U][C][G] = 2.000;
+ int22_ar[C][G][U][C][U][A][C][G] = 2.000;
+ int22_ar[C][G][U][C][U][C][C][G] = 1.400;
+ int22_ar[C][G][U][C][U][G][C][G] = -0.400;
+ int22_ar[C][G][U][C][U][U][C][G] = 0.500;
+ int22_ar[C][G][U][G][A][A][C][G] = 2.000;
+ int22_ar[C][G][U][G][A][C][C][G] = 1.300;
+ int22_ar[C][G][U][G][A][G][C][G] = -0.600;
+ int22_ar[C][G][U][G][A][U][C][G] = 1.300;
+ int22_ar[C][G][U][G][C][A][C][G] = 2.000;
+ int22_ar[C][G][U][G][C][C][C][G] = 2.000;
+ int22_ar[C][G][U][G][C][G][C][G] = 2.000;
+ int22_ar[C][G][U][G][C][U][C][G] = 2.000;
+ int22_ar[C][G][U][G][G][A][C][G] = 2.000;
+ int22_ar[C][G][U][G][G][C][C][G] = 1.700;
+ int22_ar[C][G][U][G][G][G][C][G] = -0.700;
+ int22_ar[C][G][U][G][G][U][C][G] = 1.200;
+ int22_ar[C][G][U][G][U][A][C][G] = 2.000;
+ int22_ar[C][G][U][G][U][C][C][G] = -0.400;
+ int22_ar[C][G][U][G][U][G][C][G] = -4.200;
+ int22_ar[C][G][U][G][U][U][C][G] = -0.500;
+ int22_ar[C][G][U][U][A][A][C][G] = 2.000;
+ int22_ar[C][G][U][U][A][C][C][G] = 2.000;
+ int22_ar[C][G][U][U][A][G][C][G] = 2.000;
+ int22_ar[C][G][U][U][A][U][C][G] = 2.000;
+ int22_ar[C][G][U][U][C][A][C][G] = 2.000;
+ int22_ar[C][G][U][U][C][C][C][G] = 1.400;
+ int22_ar[C][G][U][U][C][G][C][G] = -0.400;
+ int22_ar[C][G][U][U][C][U][C][G] = 0.500;
+ int22_ar[C][G][U][U][G][A][C][G] = 2.000;
+ int22_ar[C][G][U][U][G][C][C][G] = 1.100;
+ int22_ar[C][G][U][U][G][G][C][G] = -2.600;
+ int22_ar[C][G][U][U][G][U][C][G] = 1.100;
+ int22_ar[C][G][U][U][U][A][C][G] = 2.000;
+ int22_ar[C][G][U][U][U][C][C][G] = 0.500;
+ int22_ar[C][G][U][U][U][G][C][G] = -0.500;
+ int22_ar[C][G][U][U][U][U][C][G] = -0.400;
+ int22_ar[C][G][A][A][A][A][G][C] = 0.500;
+ int22_ar[C][G][A][A][A][C][G][C] = 0.600;
+ int22_ar[C][G][A][A][A][G][G][C] = 0.000;
+ int22_ar[C][G][A][A][A][U][G][C] = 2.000;
+ int22_ar[C][G][A][A][C][A][G][C] = 1.100;
+ int22_ar[C][G][A][A][C][C][G][C] = 1.500;
+ int22_ar[C][G][A][A][C][G][G][C] = -0.700;
+ int22_ar[C][G][A][A][C][U][G][C] = 2.000;
+ int22_ar[C][G][A][A][G][A][G][C] = -0.300;
+ int22_ar[C][G][A][A][G][C][G][C] = 0.100;
+ int22_ar[C][G][A][A][G][G][G][C] = -1.600;
+ int22_ar[C][G][A][A][G][U][G][C] = 2.000;
+ int22_ar[C][G][A][A][U][A][G][C] = 2.000;
+ int22_ar[C][G][A][A][U][C][G][C] = 2.000;
+ int22_ar[C][G][A][A][U][G][G][C] = 2.000;
+ int22_ar[C][G][A][A][U][U][G][C] = 2.000;
+ int22_ar[C][G][A][C][A][A][G][C] = 1.100;
+ int22_ar[C][G][A][C][A][C][G][C] = 1.100;
+ int22_ar[C][G][A][C][A][G][G][C] = -1.000;
+ int22_ar[C][G][A][C][A][U][G][C] = 2.000;
+ int22_ar[C][G][A][C][C][A][G][C] = 1.700;
+ int22_ar[C][G][A][C][C][C][G][C] = 1.500;
+ int22_ar[C][G][A][C][C][G][G][C] = -0.600;
+ int22_ar[C][G][A][C][C][U][G][C] = 2.000;
+ int22_ar[C][G][A][C][G][A][G][C] = 2.000;
+ int22_ar[C][G][A][C][G][C][G][C] = 2.000;
+ int22_ar[C][G][A][C][G][G][G][C] = 2.000;
+ int22_ar[C][G][A][C][G][U][G][C] = 2.000;
+ int22_ar[C][G][A][C][U][A][G][C] = 0.700;
+ int22_ar[C][G][A][C][U][C][G][C] = 0.500;
+ int22_ar[C][G][A][C][U][G][G][C] = 0.200;
+ int22_ar[C][G][A][C][U][U][G][C] = 2.000;
+ int22_ar[C][G][A][G][A][A][G][C] = 0.400;
+ int22_ar[C][G][A][G][A][C][G][C] = 0.500;
+ int22_ar[C][G][A][G][A][G][G][C] = -0.700;
+ int22_ar[C][G][A][G][A][U][G][C] = 2.000;
+ int22_ar[C][G][A][G][C][A][G][C] = 2.000;
+ int22_ar[C][G][A][G][C][C][G][C] = 2.000;
+ int22_ar[C][G][A][G][C][G][G][C] = 2.000;
+ int22_ar[C][G][A][G][C][U][G][C] = 2.000;
+ int22_ar[C][G][A][G][G][A][G][C] = 1.000;
+ int22_ar[C][G][A][G][G][C][G][C] = 1.400;
+ int22_ar[C][G][A][G][G][G][G][C] = 0.000;
+ int22_ar[C][G][A][G][G][U][G][C] = 2.000;
+ int22_ar[C][G][A][G][U][A][G][C] = 0.100;
+ int22_ar[C][G][A][G][U][C][G][C] = -0.700;
+ int22_ar[C][G][A][G][U][G][G][C] = -0.800;
+ int22_ar[C][G][A][G][U][U][G][C] = 2.000;
+ int22_ar[C][G][A][U][A][A][G][C] = 2.000;
+ int22_ar[C][G][A][U][A][C][G][C] = 2.000;
+ int22_ar[C][G][A][U][A][G][G][C] = 2.000;
+ int22_ar[C][G][A][U][A][U][G][C] = 2.000;
+ int22_ar[C][G][A][U][C][A][G][C] = 1.800;
+ int22_ar[C][G][A][U][C][C][G][C] = 1.500;
+ int22_ar[C][G][A][U][C][G][G][C] = 1.200;
+ int22_ar[C][G][A][U][C][U][G][C] = 2.000;
+ int22_ar[C][G][A][U][G][A][G][C] = -0.500;
+ int22_ar[C][G][A][U][G][C][G][C] = -0.600;
+ int22_ar[C][G][A][U][G][G][G][C] = -0.600;
+ int22_ar[C][G][A][U][G][U][G][C] = 2.000;
+ int22_ar[C][G][A][U][U][A][G][C] = 1.500;
+ int22_ar[C][G][A][U][U][C][G][C] = 0.000;
+ int22_ar[C][G][A][U][U][G][G][C] = 0.900;
+ int22_ar[C][G][A][U][U][U][G][C] = 2.000;
+ int22_ar[C][G][C][A][A][A][G][C] = 1.300;
+ int22_ar[C][G][C][A][A][C][G][C] = 2.200;
+ int22_ar[C][G][C][A][A][G][G][C] = 2.000;
+ int22_ar[C][G][C][A][A][U][G][C] = 2.000;
+ int22_ar[C][G][C][A][C][A][G][C] = 1.000;
+ int22_ar[C][G][C][A][C][C][G][C] = 1.300;
+ int22_ar[C][G][C][A][C][G][G][C] = 2.000;
+ int22_ar[C][G][C][A][C][U][G][C] = 1.200;
+ int22_ar[C][G][C][A][G][A][G][C] = -0.700;
+ int22_ar[C][G][C][A][G][C][G][C] = 0.700;
+ int22_ar[C][G][C][A][G][G][G][C] = 2.000;
+ int22_ar[C][G][C][A][G][U][G][C] = 0.400;
+ int22_ar[C][G][C][A][U][A][G][C] = 2.000;
+ int22_ar[C][G][C][A][U][C][G][C] = 2.000;
+ int22_ar[C][G][C][A][U][G][G][C] = 2.000;
+ int22_ar[C][G][C][A][U][U][G][C] = 2.000;
+ int22_ar[C][G][C][C][A][A][G][C] = 1.000;
+ int22_ar[C][G][C][C][A][C][G][C] = 1.900;
+ int22_ar[C][G][C][C][A][G][G][C] = 2.000;
+ int22_ar[C][G][C][C][A][U][G][C] = 1.100;
+ int22_ar[C][G][C][C][C][A][G][C] = 1.000;
+ int22_ar[C][G][C][C][C][C][G][C] = 1.300;
+ int22_ar[C][G][C][C][C][G][G][C] = 2.000;
+ int22_ar[C][G][C][C][C][U][G][C] = 1.200;
+ int22_ar[C][G][C][C][G][A][G][C] = 2.000;
+ int22_ar[C][G][C][C][G][C][G][C] = 2.000;
+ int22_ar[C][G][C][C][G][G][G][C] = 2.000;
+ int22_ar[C][G][C][C][G][U][G][C] = 2.000;
+ int22_ar[C][G][C][C][U][A][G][C] = 0.000;
+ int22_ar[C][G][C][C][U][C][G][C] = 0.300;
+ int22_ar[C][G][C][C][U][G][G][C] = 2.000;
+ int22_ar[C][G][C][C][U][U][G][C] = 1.700;
+ int22_ar[C][G][C][G][A][A][G][C] = 0.700;
+ int22_ar[C][G][C][G][A][C][G][C] = 0.700;
+ int22_ar[C][G][C][G][A][G][G][C] = 2.000;
+ int22_ar[C][G][C][G][A][U][G][C] = 1.000;
+ int22_ar[C][G][C][G][C][A][G][C] = 2.000;
+ int22_ar[C][G][C][G][C][C][G][C] = 2.000;
+ int22_ar[C][G][C][G][C][G][G][C] = 2.000;
+ int22_ar[C][G][C][G][C][U][G][C] = 2.000;
+ int22_ar[C][G][C][G][G][A][G][C] = 0.900;
+ int22_ar[C][G][C][G][G][C][G][C] = 1.800;
+ int22_ar[C][G][C][G][G][G][G][C] = 2.000;
+ int22_ar[C][G][C][G][G][U][G][C] = 1.700;
+ int22_ar[C][G][C][G][U][A][G][C] = -1.900;
+ int22_ar[C][G][C][G][U][C][G][C] = -0.300;
+ int22_ar[C][G][C][G][U][G][G][C] = 2.000;
+ int22_ar[C][G][C][G][U][U][G][C] = -0.700;
+ int22_ar[C][G][C][U][A][A][G][C] = 2.000;
+ int22_ar[C][G][C][U][A][C][G][C] = 2.000;
+ int22_ar[C][G][C][U][A][G][G][C] = 2.000;
+ int22_ar[C][G][C][U][A][U][G][C] = 2.000;
+ int22_ar[C][G][C][U][C][A][G][C] = 1.100;
+ int22_ar[C][G][C][U][C][C][G][C] = 1.400;
+ int22_ar[C][G][C][U][C][G][G][C] = 2.000;
+ int22_ar[C][G][C][U][C][U][G][C] = 1.200;
+ int22_ar[C][G][C][U][G][A][G][C] = -1.500;
+ int22_ar[C][G][C][U][G][C][G][C] = -0.200;
+ int22_ar[C][G][C][U][G][G][G][C] = 2.000;
+ int22_ar[C][G][C][U][G][U][G][C] = -0.300;
+ int22_ar[C][G][C][U][U][A][G][C] = -0.200;
+ int22_ar[C][G][C][U][U][C][G][C] = -0.100;
+ int22_ar[C][G][C][U][U][G][G][C] = 2.000;
+ int22_ar[C][G][C][U][U][U][G][C] = 0.200;
+ int22_ar[C][G][G][A][A][A][G][C] = -0.200;
+ int22_ar[C][G][G][A][A][C][G][C] = 2.000;
+ int22_ar[C][G][G][A][A][G][G][C] = 1.100;
+ int22_ar[C][G][G][A][A][U][G][C] = 0.900;
+ int22_ar[C][G][G][A][C][A][G][C] = -0.400;
+ int22_ar[C][G][G][A][C][C][G][C] = 2.000;
+ int22_ar[C][G][G][A][C][G][G][C] = 0.900;
+ int22_ar[C][G][G][A][C][U][G][C] = 0.000;
+ int22_ar[C][G][G][A][G][A][G][C] = -1.700;
+ int22_ar[C][G][G][A][G][C][G][C] = 2.000;
+ int22_ar[C][G][G][A][G][G][G][C] = -0.900;
+ int22_ar[C][G][G][A][G][U][G][C] = 0.300;
+ int22_ar[C][G][G][A][U][A][G][C] = 2.000;
+ int22_ar[C][G][G][A][U][C][G][C] = 2.000;
+ int22_ar[C][G][G][A][U][G][G][C] = 2.000;
+ int22_ar[C][G][G][A][U][U][G][C] = 2.000;
+ int22_ar[C][G][G][C][A][A][G][C] = 0.700;
+ int22_ar[C][G][G][C][A][C][G][C] = 2.000;
+ int22_ar[C][G][G][C][A][G][G][C] = 0.800;
+ int22_ar[C][G][G][C][A][U][G][C] = -0.100;
+ int22_ar[C][G][G][C][C][A][G][C] = 1.100;
+ int22_ar[C][G][G][C][C][C][G][C] = 2.000;
+ int22_ar[C][G][G][C][C][G][G][C] = 1.500;
+ int22_ar[C][G][G][C][C][U][G][C] = 1.000;
+ int22_ar[C][G][G][C][G][A][G][C] = 2.000;
+ int22_ar[C][G][G][C][G][C][G][C] = 2.000;
+ int22_ar[C][G][G][C][G][G][G][C] = 2.000;
+ int22_ar[C][G][G][C][G][U][G][C] = 2.000;
+ int22_ar[C][G][G][C][U][A][G][C] = 0.200;
+ int22_ar[C][G][G][C][U][C][G][C] = 2.000;
+ int22_ar[C][G][G][C][U][G][G][C] = 0.500;
+ int22_ar[C][G][G][C][U][U][G][C] = 0.000;
+ int22_ar[C][G][G][G][A][A][G][C] = -0.500;
+ int22_ar[C][G][G][G][A][C][G][C] = 2.000;
+ int22_ar[C][G][G][G][A][G][G][C] = -0.200;
+ int22_ar[C][G][G][G][A][U][G][C] = 0.600;
+ int22_ar[C][G][G][G][C][A][G][C] = 2.000;
+ int22_ar[C][G][G][G][C][C][G][C] = 2.000;
+ int22_ar[C][G][G][G][C][G][G][C] = 2.000;
+ int22_ar[C][G][G][G][C][U][G][C] = 2.000;
+ int22_ar[C][G][G][G][G][A][G][C] = 0.000;
+ int22_ar[C][G][G][G][G][C][G][C] = 2.000;
+ int22_ar[C][G][G][G][G][G][G][C] = 0.800;
+ int22_ar[C][G][G][G][G][U][G][C] = 0.900;
+ int22_ar[C][G][G][G][U][A][G][C] = -0.900;
+ int22_ar[C][G][G][G][U][C][G][C] = 2.000;
+ int22_ar[C][G][G][G][U][G][G][C] = -1.000;
+ int22_ar[C][G][G][G][U][U][G][C] = -3.000;
+ int22_ar[C][G][G][U][A][A][G][C] = 2.000;
+ int22_ar[C][G][G][U][A][C][G][C] = 2.000;
+ int22_ar[C][G][G][U][A][G][G][C] = 2.000;
+ int22_ar[C][G][G][U][A][U][G][C] = 2.000;
+ int22_ar[C][G][G][U][C][A][G][C] = 1.200;
+ int22_ar[C][G][G][U][C][C][G][C] = 2.000;
+ int22_ar[C][G][G][U][C][G][G][C] = 1.500;
+ int22_ar[C][G][G][U][C][U][G][C] = 1.000;
+ int22_ar[C][G][G][U][G][A][G][C] = -1.300;
+ int22_ar[C][G][G][U][G][C][G][C] = 2.000;
+ int22_ar[C][G][G][U][G][G][G][C] = -0.600;
+ int22_ar[C][G][G][U][G][U][G][C] = -2.400;
+ int22_ar[C][G][G][U][U][A][G][C] = 0.900;
+ int22_ar[C][G][G][U][U][C][G][C] = 2.000;
+ int22_ar[C][G][G][U][U][G][G][C] = 1.100;
+ int22_ar[C][G][G][U][U][U][G][C] = 0.600;
+ int22_ar[C][G][U][A][A][A][G][C] = 2.000;
+ int22_ar[C][G][U][A][A][C][G][C] = 2.000;
+ int22_ar[C][G][U][A][A][G][G][C] = -0.100;
+ int22_ar[C][G][U][A][A][U][G][C] = 1.400;
+ int22_ar[C][G][U][A][C][A][G][C] = 2.000;
+ int22_ar[C][G][U][A][C][C][G][C] = 1.200;
+ int22_ar[C][G][U][A][C][G][G][C] = -1.600;
+ int22_ar[C][G][U][A][C][U][G][C] = 0.300;
+ int22_ar[C][G][U][A][G][A][G][C] = 2.000;
+ int22_ar[C][G][U][A][G][C][G][C] = 0.400;
+ int22_ar[C][G][U][A][G][G][G][C] = -1.600;
+ int22_ar[C][G][U][A][G][U][G][C] = 0.500;
+ int22_ar[C][G][U][A][U][A][G][C] = 2.000;
+ int22_ar[C][G][U][A][U][C][G][C] = 2.000;
+ int22_ar[C][G][U][A][U][G][G][C] = 2.000;
+ int22_ar[C][G][U][A][U][U][G][C] = 2.000;
+ int22_ar[C][G][U][C][A][A][G][C] = 2.000;
+ int22_ar[C][G][U][C][A][C][G][C] = 1.100;
+ int22_ar[C][G][U][C][A][G][G][C] = -1.600;
+ int22_ar[C][G][U][C][A][U][G][C] = 0.300;
+ int22_ar[C][G][U][C][C][A][G][C] = 2.000;
+ int22_ar[C][G][U][C][C][C][G][C] = 1.200;
+ int22_ar[C][G][U][C][C][G][G][C] = -0.600;
+ int22_ar[C][G][U][C][C][U][G][C] = 0.300;
+ int22_ar[C][G][U][C][G][A][G][C] = 2.000;
+ int22_ar[C][G][U][C][G][C][G][C] = 2.000;
+ int22_ar[C][G][U][C][G][G][G][C] = 2.000;
+ int22_ar[C][G][U][C][G][U][G][C] = 2.000;
+ int22_ar[C][G][U][C][U][A][G][C] = 2.000;
+ int22_ar[C][G][U][C][U][C][G][C] = 0.200;
+ int22_ar[C][G][U][C][U][G][G][C] = -1.600;
+ int22_ar[C][G][U][C][U][U][G][C] = 0.100;
+ int22_ar[C][G][U][G][A][A][G][C] = 2.000;
+ int22_ar[C][G][U][G][A][C][G][C] = 0.500;
+ int22_ar[C][G][U][G][A][G][G][C] = -0.600;
+ int22_ar[C][G][U][G][A][U][G][C] = 1.400;
+ int22_ar[C][G][U][G][C][A][G][C] = 2.000;
+ int22_ar[C][G][U][G][C][C][G][C] = 2.000;
+ int22_ar[C][G][U][G][C][G][G][C] = 2.000;
+ int22_ar[C][G][U][G][C][U][G][C] = 2.000;
+ int22_ar[C][G][U][G][G][A][G][C] = 2.000;
+ int22_ar[C][G][U][G][G][C][G][C] = 1.700;
+ int22_ar[C][G][U][G][G][G][G][C] = -0.700;
+ int22_ar[C][G][U][G][G][U][G][C] = 1.200;
+ int22_ar[C][G][U][G][U][A][G][C] = 2.000;
+ int22_ar[C][G][U][G][U][C][G][C] = -0.700;
+ int22_ar[C][G][U][G][U][G][G][C] = -4.400;
+ int22_ar[C][G][U][G][U][U][G][C] = -1.000;
+ int22_ar[C][G][U][U][A][A][G][C] = 2.000;
+ int22_ar[C][G][U][U][A][C][G][C] = 2.000;
+ int22_ar[C][G][U][U][A][G][G][C] = 2.000;
+ int22_ar[C][G][U][U][A][U][G][C] = 2.000;
+ int22_ar[C][G][U][U][C][A][G][C] = 2.000;
+ int22_ar[C][G][U][U][C][C][G][C] = 1.200;
+ int22_ar[C][G][U][U][C][G][G][C] = -0.500;
+ int22_ar[C][G][U][U][C][U][G][C] = 0.300;
+ int22_ar[C][G][U][U][G][A][G][C] = 2.000;
+ int22_ar[C][G][U][U][G][C][G][C] = -0.100;
+ int22_ar[C][G][U][U][G][G][G][C] = -4.100;
+ int22_ar[C][G][U][U][G][U][G][C] = 0.100;
+ int22_ar[C][G][U][U][U][A][G][C] = 2.000;
+ int22_ar[C][G][U][U][U][C][G][C] = 0.400;
+ int22_ar[C][G][U][U][U][G][G][C] = -1.000;
+ int22_ar[C][G][U][U][U][U][G][C] = 0.600;
+ int22_ar[C][G][A][A][A][A][G][U] = 2.000;
+ int22_ar[C][G][A][A][A][C][G][U] = 2.400;
+ int22_ar[C][G][A][A][A][G][G][U] = 1.000;
+ int22_ar[C][G][A][A][A][U][G][U] = 2.000;
+ int22_ar[C][G][A][A][C][A][G][U] = 1.800;
+ int22_ar[C][G][A][A][C][C][G][U] = 2.100;
+ int22_ar[C][G][A][A][C][G][G][U] = 0.800;
+ int22_ar[C][G][A][A][C][U][G][U] = 2.000;
+ int22_ar[C][G][A][A][G][A][G][U] = 0.800;
+ int22_ar[C][G][A][A][G][C][G][U] = 1.100;
+ int22_ar[C][G][A][A][G][G][G][U] = -0.200;
+ int22_ar[C][G][A][A][G][U][G][U] = 2.000;
+ int22_ar[C][G][A][A][U][A][G][U] = 2.000;
+ int22_ar[C][G][A][A][U][C][G][U] = 2.000;
+ int22_ar[C][G][A][A][U][G][G][U] = 2.000;
+ int22_ar[C][G][A][A][U][U][G][U] = 2.000;
+ int22_ar[C][G][A][C][A][A][G][U] = 1.900;
+ int22_ar[C][G][A][C][A][C][G][U] = 2.200;
+ int22_ar[C][G][A][C][A][G][G][U] = 0.900;
+ int22_ar[C][G][A][C][A][U][G][U] = 2.000;
+ int22_ar[C][G][A][C][C][A][G][U] = 2.300;
+ int22_ar[C][G][A][C][C][C][G][U] = 2.100;
+ int22_ar[C][G][A][C][C][G][G][U] = 1.700;
+ int22_ar[C][G][A][C][C][U][G][U] = 2.000;
+ int22_ar[C][G][A][C][G][A][G][U] = 2.000;
+ int22_ar[C][G][A][C][G][C][G][U] = 2.000;
+ int22_ar[C][G][A][C][G][G][G][U] = 2.000;
+ int22_ar[C][G][A][C][G][U][G][U] = 2.000;
+ int22_ar[C][G][A][C][U][A][G][U] = 2.300;
+ int22_ar[C][G][A][C][U][C][G][U] = 2.100;
+ int22_ar[C][G][A][C][U][G][G][U] = 1.700;
+ int22_ar[C][G][A][C][U][U][G][U] = 2.000;
+ int22_ar[C][G][A][G][A][A][G][U] = 0.800;
+ int22_ar[C][G][A][G][A][C][G][U] = 1.100;
+ int22_ar[C][G][A][G][A][G][G][U] = -0.200;
+ int22_ar[C][G][A][G][A][U][G][U] = 2.000;
+ int22_ar[C][G][A][G][C][A][G][U] = 2.000;
+ int22_ar[C][G][A][G][C][C][G][U] = 2.000;
+ int22_ar[C][G][A][G][C][G][G][U] = 2.000;
+ int22_ar[C][G][A][G][C][U][G][U] = 2.000;
+ int22_ar[C][G][A][G][G][A][G][U] = 1.300;
+ int22_ar[C][G][A][G][G][C][G][U] = 1.700;
+ int22_ar[C][G][A][G][G][G][G][U] = 0.300;
+ int22_ar[C][G][A][G][G][U][G][U] = 2.000;
+ int22_ar[C][G][A][G][U][A][G][U] = 0.600;
+ int22_ar[C][G][A][G][U][C][G][U] = 0.000;
+ int22_ar[C][G][A][G][U][G][G][U] = 0.400;
+ int22_ar[C][G][A][G][U][U][G][U] = 2.000;
+ int22_ar[C][G][A][U][A][A][G][U] = 2.000;
+ int22_ar[C][G][A][U][A][C][G][U] = 2.000;
+ int22_ar[C][G][A][U][A][G][G][U] = 2.000;
+ int22_ar[C][G][A][U][A][U][G][U] = 2.000;
+ int22_ar[C][G][A][U][C][A][G][U] = 2.300;
+ int22_ar[C][G][A][U][C][C][G][U] = 2.100;
+ int22_ar[C][G][A][U][C][G][G][U] = 1.700;
+ int22_ar[C][G][A][U][C][U][G][U] = 2.000;
+ int22_ar[C][G][A][U][G][A][G][U] = 1.600;
+ int22_ar[C][G][A][U][G][C][G][U] = 0.900;
+ int22_ar[C][G][A][U][G][G][G][U] = 1.400;
+ int22_ar[C][G][A][U][G][U][G][U] = 2.000;
+ int22_ar[C][G][A][U][U][A][G][U] = 1.900;
+ int22_ar[C][G][A][U][U][C][G][U] = 1.300;
+ int22_ar[C][G][A][U][U][G][G][U] = 1.800;
+ int22_ar[C][G][A][U][U][U][G][U] = 2.000;
+ int22_ar[C][G][C][A][A][A][G][U] = 1.900;
+ int22_ar[C][G][C][A][A][C][G][U] = 2.800;
+ int22_ar[C][G][C][A][A][G][G][U] = 2.000;
+ int22_ar[C][G][C][A][A][U][G][U] = 2.700;
+ int22_ar[C][G][C][A][C][A][G][U] = 1.700;
+ int22_ar[C][G][C][A][C][C][G][U] = 2.000;
+ int22_ar[C][G][C][A][C][G][G][U] = 2.000;
+ int22_ar[C][G][C][A][C][U][G][U] = 1.800;
+ int22_ar[C][G][C][A][G][A][G][U] = 0.700;
+ int22_ar[C][G][C][A][G][C][G][U] = 2.000;
+ int22_ar[C][G][C][A][G][G][G][U] = 2.000;
+ int22_ar[C][G][C][A][G][U][G][U] = 1.800;
+ int22_ar[C][G][C][A][U][A][G][U] = 2.000;
+ int22_ar[C][G][C][A][U][C][G][U] = 2.000;
+ int22_ar[C][G][C][A][U][G][G][U] = 2.000;
+ int22_ar[C][G][C][A][U][U][G][U] = 2.000;
+ int22_ar[C][G][C][C][A][A][G][U] = 1.800;
+ int22_ar[C][G][C][C][A][C][G][U] = 2.100;
+ int22_ar[C][G][C][C][A][G][G][U] = 2.000;
+ int22_ar[C][G][C][C][A][U][G][U] = 1.900;
+ int22_ar[C][G][C][C][C][A][G][U] = 1.600;
+ int22_ar[C][G][C][C][C][C][G][U] = 1.900;
+ int22_ar[C][G][C][C][C][G][G][U] = 2.000;
+ int22_ar[C][G][C][C][C][U][G][U] = 1.800;
+ int22_ar[C][G][C][C][G][A][G][U] = 2.000;
+ int22_ar[C][G][C][C][G][C][G][U] = 2.000;
+ int22_ar[C][G][C][C][G][G][G][U] = 2.000;
+ int22_ar[C][G][C][C][G][U][G][U] = 2.000;
+ int22_ar[C][G][C][C][U][A][G][U] = 1.600;
+ int22_ar[C][G][C][C][U][C][G][U] = 1.900;
+ int22_ar[C][G][C][C][U][G][G][U] = 2.000;
+ int22_ar[C][G][C][C][U][U][G][U] = 1.800;
+ int22_ar[C][G][C][G][A][A][G][U] = 0.700;
+ int22_ar[C][G][C][G][A][C][G][U] = 2.000;
+ int22_ar[C][G][C][G][A][G][G][U] = 2.000;
+ int22_ar[C][G][C][G][A][U][G][U] = 1.800;
+ int22_ar[C][G][C][G][C][A][G][U] = 2.000;
+ int22_ar[C][G][C][G][C][C][G][U] = 2.000;
+ int22_ar[C][G][C][G][C][G][G][U] = 2.000;
+ int22_ar[C][G][C][G][C][U][G][U] = 2.000;
+ int22_ar[C][G][C][G][G][A][G][U] = 1.200;
+ int22_ar[C][G][C][G][G][C][G][U] = 2.100;
+ int22_ar[C][G][C][G][G][G][G][U] = 2.000;
+ int22_ar[C][G][C][G][G][U][G][U] = 2.000;
+ int22_ar[C][G][C][G][U][A][G][U] = -0.500;
+ int22_ar[C][G][C][G][U][C][G][U] = 0.800;
+ int22_ar[C][G][C][G][U][G][G][U] = 2.000;
+ int22_ar[C][G][C][G][U][U][G][U] = 0.700;
+ int22_ar[C][G][C][U][A][A][G][U] = 2.000;
+ int22_ar[C][G][C][U][A][C][G][U] = 2.000;
+ int22_ar[C][G][C][U][A][G][G][U] = 2.000;
+ int22_ar[C][G][C][U][A][U][G][U] = 2.000;
+ int22_ar[C][G][C][U][C][A][G][U] = 1.600;
+ int22_ar[C][G][C][U][C][C][G][U] = 1.900;
+ int22_ar[C][G][C][U][C][G][G][U] = 2.000;
+ int22_ar[C][G][C][U][C][U][G][U] = 1.800;
+ int22_ar[C][G][C][U][G][A][G][U] = 0.500;
+ int22_ar[C][G][C][U][G][C][G][U] = 1.800;
+ int22_ar[C][G][C][U][G][G][G][U] = 2.000;
+ int22_ar[C][G][C][U][G][U][G][U] = 1.600;
+ int22_ar[C][G][C][U][U][A][G][U] = 0.800;
+ int22_ar[C][G][C][U][U][C][G][U] = 1.100;
+ int22_ar[C][G][C][U][U][G][G][U] = 2.000;
+ int22_ar[C][G][C][U][U][U][G][U] = 1.000;
+ int22_ar[C][G][G][A][A][A][G][U] = 1.000;
+ int22_ar[C][G][G][A][A][C][G][U] = 2.000;
+ int22_ar[C][G][G][A][A][G][G][U] = 1.800;
+ int22_ar[C][G][G][A][A][U][G][U] = 1.800;
+ int22_ar[C][G][G][A][C][A][G][U] = 0.800;
+ int22_ar[C][G][G][A][C][C][G][U] = 2.000;
+ int22_ar[C][G][G][A][C][G][G][U] = 1.500;
+ int22_ar[C][G][G][A][C][U][G][U] = 0.600;
+ int22_ar[C][G][G][A][G][A][G][U] = -0.200;
+ int22_ar[C][G][G][A][G][C][G][U] = 2.000;
+ int22_ar[C][G][G][A][G][G][G][U] = 0.500;
+ int22_ar[C][G][G][A][G][U][G][U] = 1.400;
+ int22_ar[C][G][G][A][U][A][G][U] = 2.000;
+ int22_ar[C][G][G][A][U][C][G][U] = 2.000;
+ int22_ar[C][G][G][A][U][G][G][U] = 2.000;
+ int22_ar[C][G][G][A][U][U][G][U] = 2.000;
+ int22_ar[C][G][G][C][A][A][G][U] = 0.900;
+ int22_ar[C][G][G][C][A][C][G][U] = 2.000;
+ int22_ar[C][G][G][C][A][G][G][U] = 1.600;
+ int22_ar[C][G][G][C][A][U][G][U] = 0.700;
+ int22_ar[C][G][G][C][C][A][G][U] = 1.700;
+ int22_ar[C][G][G][C][C][C][G][U] = 2.000;
+ int22_ar[C][G][G][C][C][G][G][U] = 2.100;
+ int22_ar[C][G][G][C][C][U][G][U] = 1.500;
+ int22_ar[C][G][G][C][G][A][G][U] = 2.000;
+ int22_ar[C][G][G][C][G][C][G][U] = 2.000;
+ int22_ar[C][G][G][C][G][G][G][U] = 2.000;
+ int22_ar[C][G][G][C][G][U][G][U] = 2.000;
+ int22_ar[C][G][G][C][U][A][G][U] = 1.700;
+ int22_ar[C][G][G][C][U][C][G][U] = 2.000;
+ int22_ar[C][G][G][C][U][G][G][U] = 2.100;
+ int22_ar[C][G][G][C][U][U][G][U] = 1.500;
+ int22_ar[C][G][G][G][A][A][G][U] = -0.200;
+ int22_ar[C][G][G][G][A][C][G][U] = 2.000;
+ int22_ar[C][G][G][G][A][G][G][U] = 0.500;
+ int22_ar[C][G][G][G][A][U][G][U] = 1.400;
+ int22_ar[C][G][G][G][C][A][G][U] = 2.000;
+ int22_ar[C][G][G][G][C][C][G][U] = 2.000;
+ int22_ar[C][G][G][G][C][G][G][U] = 2.000;
+ int22_ar[C][G][G][G][C][U][G][U] = 2.000;
+ int22_ar[C][G][G][G][G][A][G][U] = 0.300;
+ int22_ar[C][G][G][G][G][C][G][U] = 2.000;
+ int22_ar[C][G][G][G][G][G][G][U] = 1.100;
+ int22_ar[C][G][G][G][G][U][G][U] = 1.100;
+ int22_ar[C][G][G][G][U][A][G][U] = 0.400;
+ int22_ar[C][G][G][G][U][C][G][U] = 2.000;
+ int22_ar[C][G][G][G][U][G][G][U] = 0.400;
+ int22_ar[C][G][G][G][U][U][G][U] = -1.600;
+ int22_ar[C][G][G][U][A][A][G][U] = 2.000;
+ int22_ar[C][G][G][U][A][C][G][U] = 2.000;
+ int22_ar[C][G][G][U][A][G][G][U] = 2.000;
+ int22_ar[C][G][G][U][A][U][G][U] = 2.000;
+ int22_ar[C][G][G][U][C][A][G][U] = 1.700;
+ int22_ar[C][G][G][U][C][C][G][U] = 2.000;
+ int22_ar[C][G][G][U][C][G][G][U] = 2.100;
+ int22_ar[C][G][G][U][C][U][G][U] = 1.500;
+ int22_ar[C][G][G][U][G][A][G][U] = 1.400;
+ int22_ar[C][G][G][U][G][C][G][U] = 2.000;
+ int22_ar[C][G][G][U][G][G][G][U] = 1.300;
+ int22_ar[C][G][G][U][G][U][G][U] = -0.600;
+ int22_ar[C][G][G][U][U][A][G][U] = 1.800;
+ int22_ar[C][G][G][U][U][C][G][U] = 2.000;
+ int22_ar[C][G][G][U][U][G][G][U] = 1.700;
+ int22_ar[C][G][G][U][U][U][G][U] = 1.600;
+ int22_ar[C][G][U][A][A][A][G][U] = 2.000;
+ int22_ar[C][G][U][A][A][C][G][U] = 2.700;
+ int22_ar[C][G][U][A][A][G][G][U] = 0.300;
+ int22_ar[C][G][U][A][A][U][G][U] = 2.200;
+ int22_ar[C][G][U][A][C][A][G][U] = 2.000;
+ int22_ar[C][G][U][A][C][C][G][U] = 1.800;
+ int22_ar[C][G][U][A][C][G][G][U] = -0.900;
+ int22_ar[C][G][U][A][C][U][G][U] = 0.900;
+ int22_ar[C][G][U][A][G][A][G][U] = 2.000;
+ int22_ar[C][G][U][A][G][C][G][U] = 1.800;
+ int22_ar[C][G][U][A][G][G][G][U] = -0.100;
+ int22_ar[C][G][U][A][G][U][G][U] = 1.800;
+ int22_ar[C][G][U][A][U][A][G][U] = 2.000;
+ int22_ar[C][G][U][A][U][C][G][U] = 2.000;
+ int22_ar[C][G][U][A][U][G][G][U] = 2.000;
+ int22_ar[C][G][U][A][U][U][G][U] = 2.000;
+ int22_ar[C][G][U][C][A][A][G][U] = 2.000;
+ int22_ar[C][G][U][C][A][C][G][U] = 1.900;
+ int22_ar[C][G][U][C][A][G][G][U] = -0.800;
+ int22_ar[C][G][U][C][A][U][G][U] = 1.000;
+ int22_ar[C][G][U][C][C][A][G][U] = 2.000;
+ int22_ar[C][G][U][C][C][C][G][U] = 1.800;
+ int22_ar[C][G][U][C][C][G][G][U] = 0.000;
+ int22_ar[C][G][U][C][C][U][G][U] = 0.900;
+ int22_ar[C][G][U][C][G][A][G][U] = 2.000;
+ int22_ar[C][G][U][C][G][C][G][U] = 2.000;
+ int22_ar[C][G][U][C][G][G][G][U] = 2.000;
+ int22_ar[C][G][U][C][G][U][G][U] = 2.000;
+ int22_ar[C][G][U][C][U][A][G][U] = 2.000;
+ int22_ar[C][G][U][C][U][C][G][U] = 1.800;
+ int22_ar[C][G][U][C][U][G][G][U] = 0.000;
+ int22_ar[C][G][U][C][U][U][G][U] = 0.900;
+ int22_ar[C][G][U][G][A][A][G][U] = 2.000;
+ int22_ar[C][G][U][G][A][C][G][U] = 1.800;
+ int22_ar[C][G][U][G][A][G][G][U] = -0.100;
+ int22_ar[C][G][U][G][A][U][G][U] = 1.800;
+ int22_ar[C][G][U][G][C][A][G][U] = 2.000;
+ int22_ar[C][G][U][G][C][C][G][U] = 2.000;
+ int22_ar[C][G][U][G][C][G][G][U] = 2.000;
+ int22_ar[C][G][U][G][C][U][G][U] = 2.000;
+ int22_ar[C][G][U][G][G][A][G][U] = 2.000;
+ int22_ar[C][G][U][G][G][C][G][U] = 2.000;
+ int22_ar[C][G][U][G][G][G][G][U] = -0.400;
+ int22_ar[C][G][U][G][G][U][G][U] = 1.500;
+ int22_ar[C][G][U][G][U][A][G][U] = 2.000;
+ int22_ar[C][G][U][G][U][C][G][U] = 0.700;
+ int22_ar[C][G][U][G][U][G][G][U] = -3.100;
+ int22_ar[C][G][U][G][U][U][G][U] = 0.600;
+ int22_ar[C][G][U][U][A][A][G][U] = 2.000;
+ int22_ar[C][G][U][U][A][C][G][U] = 2.000;
+ int22_ar[C][G][U][U][A][G][G][U] = 2.000;
+ int22_ar[C][G][U][U][A][U][G][U] = 2.000;
+ int22_ar[C][G][U][U][C][A][G][U] = 2.000;
+ int22_ar[C][G][U][U][C][C][G][U] = 1.800;
+ int22_ar[C][G][U][U][C][G][G][U] = 0.000;
+ int22_ar[C][G][U][U][C][U][G][U] = 0.900;
+ int22_ar[C][G][U][U][G][A][G][U] = 2.000;
+ int22_ar[C][G][U][U][G][C][G][U] = 1.600;
+ int22_ar[C][G][U][U][G][G][G][U] = -2.100;
+ int22_ar[C][G][U][U][G][U][G][U] = 1.600;
+ int22_ar[C][G][U][U][U][A][G][U] = 2.000;
+ int22_ar[C][G][U][U][U][C][G][U] = 1.000;
+ int22_ar[C][G][U][U][U][G][G][U] = 0.000;
+ int22_ar[C][G][U][U][U][U][G][U] = 0.100;
+ int22_ar[C][G][A][A][A][A][U][A] = 2.000;
+ int22_ar[C][G][A][A][A][C][U][A] = 2.400;
+ int22_ar[C][G][A][A][A][G][U][A] = 1.000;
+ int22_ar[C][G][A][A][A][U][U][A] = 2.000;
+ int22_ar[C][G][A][A][C][A][U][A] = 1.600;
+ int22_ar[C][G][A][A][C][C][U][A] = 1.900;
+ int22_ar[C][G][A][A][C][G][U][A] = 0.600;
+ int22_ar[C][G][A][A][C][U][U][A] = 2.000;
+ int22_ar[C][G][A][A][G][A][U][A] = 1.000;
+ int22_ar[C][G][A][A][G][C][U][A] = 1.300;
+ int22_ar[C][G][A][A][G][G][U][A] = 0.000;
+ int22_ar[C][G][A][A][G][U][U][A] = 2.000;
+ int22_ar[C][G][A][A][U][A][U][A] = 2.000;
+ int22_ar[C][G][A][A][U][C][U][A] = 2.000;
+ int22_ar[C][G][A][A][U][G][U][A] = 2.000;
+ int22_ar[C][G][A][A][U][U][U][A] = 2.000;
+ int22_ar[C][G][A][C][A][A][U][A] = 2.000;
+ int22_ar[C][G][A][C][A][C][U][A] = 2.400;
+ int22_ar[C][G][A][C][A][G][U][A] = 1.000;
+ int22_ar[C][G][A][C][A][U][U][A] = 2.000;
+ int22_ar[C][G][A][C][C][A][U][A] = 2.600;
+ int22_ar[C][G][A][C][C][C][U][A] = 2.400;
+ int22_ar[C][G][A][C][C][G][U][A] = 2.000;
+ int22_ar[C][G][A][C][C][U][U][A] = 2.000;
+ int22_ar[C][G][A][C][G][A][U][A] = 2.000;
+ int22_ar[C][G][A][C][G][C][U][A] = 2.000;
+ int22_ar[C][G][A][C][G][G][U][A] = 2.000;
+ int22_ar[C][G][A][C][G][U][U][A] = 2.000;
+ int22_ar[C][G][A][C][U][A][U][A] = 2.600;
+ int22_ar[C][G][A][C][U][C][U][A] = 2.400;
+ int22_ar[C][G][A][C][U][G][U][A] = 2.000;
+ int22_ar[C][G][A][C][U][U][U][A] = 2.000;
+ int22_ar[C][G][A][G][A][A][U][A] = 1.000;
+ int22_ar[C][G][A][G][A][C][U][A] = 1.300;
+ int22_ar[C][G][A][G][A][G][U][A] = 0.000;
+ int22_ar[C][G][A][G][A][U][U][A] = 2.000;
+ int22_ar[C][G][A][G][C][A][U][A] = 2.000;
+ int22_ar[C][G][A][G][C][C][U][A] = 2.000;
+ int22_ar[C][G][A][G][C][G][U][A] = 2.000;
+ int22_ar[C][G][A][G][C][U][U][A] = 2.000;
+ int22_ar[C][G][A][G][G][A][U][A] = 1.400;
+ int22_ar[C][G][A][G][G][C][U][A] = 1.700;
+ int22_ar[C][G][A][G][G][G][U][A] = 0.400;
+ int22_ar[C][G][A][G][G][U][U][A] = 2.000;
+ int22_ar[C][G][A][G][U][A][U][A] = 0.200;
+ int22_ar[C][G][A][G][U][C][U][A] = -0.400;
+ int22_ar[C][G][A][G][U][G][U][A] = 0.000;
+ int22_ar[C][G][A][G][U][U][U][A] = 2.000;
+ int22_ar[C][G][A][U][A][A][U][A] = 2.000;
+ int22_ar[C][G][A][U][A][C][U][A] = 2.000;
+ int22_ar[C][G][A][U][A][G][U][A] = 2.000;
+ int22_ar[C][G][A][U][A][U][U][A] = 2.000;
+ int22_ar[C][G][A][U][C][A][U][A] = 2.300;
+ int22_ar[C][G][A][U][C][C][U][A] = 2.100;
+ int22_ar[C][G][A][U][C][G][U][A] = 1.700;
+ int22_ar[C][G][A][U][C][U][U][A] = 2.000;
+ int22_ar[C][G][A][U][G][A][U][A] = 1.500;
+ int22_ar[C][G][A][U][G][C][U][A] = 0.800;
+ int22_ar[C][G][A][U][G][G][U][A] = 1.300;
+ int22_ar[C][G][A][U][G][U][U][A] = 2.000;
+ int22_ar[C][G][A][U][U][A][U][A] = 2.200;
+ int22_ar[C][G][A][U][U][C][U][A] = 1.500;
+ int22_ar[C][G][A][U][U][G][U][A] = 2.000;
+ int22_ar[C][G][A][U][U][U][U][A] = 2.000;
+ int22_ar[C][G][C][A][A][A][U][A] = 1.900;
+ int22_ar[C][G][C][A][A][C][U][A] = 2.800;
+ int22_ar[C][G][C][A][A][G][U][A] = 2.000;
+ int22_ar[C][G][C][A][A][U][U][A] = 2.700;
+ int22_ar[C][G][C][A][C][A][U][A] = 1.500;
+ int22_ar[C][G][C][A][C][C][U][A] = 1.800;
+ int22_ar[C][G][C][A][C][G][U][A] = 2.000;
+ int22_ar[C][G][C][A][C][U][U][A] = 1.600;
+ int22_ar[C][G][C][A][G][A][U][A] = 0.900;
+ int22_ar[C][G][C][A][G][C][U][A] = 2.200;
+ int22_ar[C][G][C][A][G][G][U][A] = 2.000;
+ int22_ar[C][G][C][A][G][U][U][A] = 2.000;
+ int22_ar[C][G][C][A][U][A][U][A] = 2.000;
+ int22_ar[C][G][C][A][U][C][U][A] = 2.000;
+ int22_ar[C][G][C][A][U][G][U][A] = 2.000;
+ int22_ar[C][G][C][A][U][U][U][A] = 2.000;
+ int22_ar[C][G][C][C][A][A][U][A] = 1.900;
+ int22_ar[C][G][C][C][A][C][U][A] = 2.200;
+ int22_ar[C][G][C][C][A][G][U][A] = 2.000;
+ int22_ar[C][G][C][C][A][U][U][A] = 2.100;
+ int22_ar[C][G][C][C][C][A][U][A] = 1.900;
+ int22_ar[C][G][C][C][C][C][U][A] = 2.200;
+ int22_ar[C][G][C][C][C][G][U][A] = 2.000;
+ int22_ar[C][G][C][C][C][U][U][A] = 2.100;
+ int22_ar[C][G][C][C][G][A][U][A] = 2.000;
+ int22_ar[C][G][C][C][G][C][U][A] = 2.000;
+ int22_ar[C][G][C][C][G][G][U][A] = 2.000;
+ int22_ar[C][G][C][C][G][U][U][A] = 2.000;
+ int22_ar[C][G][C][C][U][A][U][A] = 1.900;
+ int22_ar[C][G][C][C][U][C][U][A] = 2.200;
+ int22_ar[C][G][C][C][U][G][U][A] = 2.000;
+ int22_ar[C][G][C][C][U][U][U][A] = 2.100;
+ int22_ar[C][G][C][G][A][A][U][A] = 0.900;
+ int22_ar[C][G][C][G][A][C][U][A] = 2.200;
+ int22_ar[C][G][C][G][A][G][U][A] = 2.000;
+ int22_ar[C][G][C][G][A][U][U][A] = 2.000;
+ int22_ar[C][G][C][G][C][A][U][A] = 2.000;
+ int22_ar[C][G][C][G][C][C][U][A] = 2.000;
+ int22_ar[C][G][C][G][C][G][U][A] = 2.000;
+ int22_ar[C][G][C][G][C][U][U][A] = 2.000;
+ int22_ar[C][G][C][G][G][A][U][A] = 1.300;
+ int22_ar[C][G][C][G][G][C][U][A] = 2.200;
+ int22_ar[C][G][C][G][G][G][U][A] = 2.000;
+ int22_ar[C][G][C][G][G][U][U][A] = 2.000;
+ int22_ar[C][G][C][G][U][A][U][A] = -0.900;
+ int22_ar[C][G][C][G][U][C][U][A] = 0.400;
+ int22_ar[C][G][C][G][U][G][U][A] = 2.000;
+ int22_ar[C][G][C][G][U][U][U][A] = 0.300;
+ int22_ar[C][G][C][U][A][A][U][A] = 2.000;
+ int22_ar[C][G][C][U][A][C][U][A] = 2.000;
+ int22_ar[C][G][C][U][A][G][U][A] = 2.000;
+ int22_ar[C][G][C][U][A][U][U][A] = 2.000;
+ int22_ar[C][G][C][U][C][A][U][A] = 1.600;
+ int22_ar[C][G][C][U][C][C][U][A] = 1.900;
+ int22_ar[C][G][C][U][C][G][U][A] = 2.000;
+ int22_ar[C][G][C][U][C][U][U][A] = 1.800;
+ int22_ar[C][G][C][U][G][A][U][A] = 0.400;
+ int22_ar[C][G][C][U][G][C][U][A] = 1.700;
+ int22_ar[C][G][C][U][G][G][U][A] = 2.000;
+ int22_ar[C][G][C][U][G][U][U][A] = 1.500;
+ int22_ar[C][G][C][U][U][A][U][A] = 1.100;
+ int22_ar[C][G][C][U][U][C][U][A] = 1.400;
+ int22_ar[C][G][C][U][U][G][U][A] = 2.000;
+ int22_ar[C][G][C][U][U][U][U][A] = 1.200;
+ int22_ar[C][G][G][A][A][A][U][A] = 1.000;
+ int22_ar[C][G][G][A][A][C][U][A] = 2.000;
+ int22_ar[C][G][G][A][A][G][U][A] = 1.800;
+ int22_ar[C][G][G][A][A][U][U][A] = 1.800;
+ int22_ar[C][G][G][A][C][A][U][A] = 0.600;
+ int22_ar[C][G][G][A][C][C][U][A] = 2.000;
+ int22_ar[C][G][G][A][C][G][U][A] = 1.300;
+ int22_ar[C][G][G][A][C][U][U][A] = 0.400;
+ int22_ar[C][G][G][A][G][A][U][A] = 0.000;
+ int22_ar[C][G][G][A][G][C][U][A] = 2.000;
+ int22_ar[C][G][G][A][G][G][U][A] = 0.700;
+ int22_ar[C][G][G][A][G][U][U][A] = 1.600;
+ int22_ar[C][G][G][A][U][A][U][A] = 2.000;
+ int22_ar[C][G][G][A][U][C][U][A] = 2.000;
+ int22_ar[C][G][G][A][U][G][U][A] = 2.000;
+ int22_ar[C][G][G][A][U][U][U][A] = 2.000;
+ int22_ar[C][G][G][C][A][A][U][A] = 1.000;
+ int22_ar[C][G][G][C][A][C][U][A] = 2.000;
+ int22_ar[C][G][G][C][A][G][U][A] = 1.800;
+ int22_ar[C][G][G][C][A][U][U][A] = 0.800;
+ int22_ar[C][G][G][C][C][A][U][A] = 2.000;
+ int22_ar[C][G][G][C][C][C][U][A] = 2.000;
+ int22_ar[C][G][G][C][C][G][U][A] = 2.400;
+ int22_ar[C][G][G][C][C][U][U][A] = 1.800;
+ int22_ar[C][G][G][C][G][A][U][A] = 2.000;
+ int22_ar[C][G][G][C][G][C][U][A] = 2.000;
+ int22_ar[C][G][G][C][G][G][U][A] = 2.000;
+ int22_ar[C][G][G][C][G][U][U][A] = 2.000;
+ int22_ar[C][G][G][C][U][A][U][A] = 2.000;
+ int22_ar[C][G][G][C][U][C][U][A] = 2.000;
+ int22_ar[C][G][G][C][U][G][U][A] = 2.400;
+ int22_ar[C][G][G][C][U][U][U][A] = 1.800;
+ int22_ar[C][G][G][G][A][A][U][A] = 0.000;
+ int22_ar[C][G][G][G][A][C][U][A] = 2.000;
+ int22_ar[C][G][G][G][A][G][U][A] = 0.700;
+ int22_ar[C][G][G][G][A][U][U][A] = 1.600;
+ int22_ar[C][G][G][G][C][A][U][A] = 2.000;
+ int22_ar[C][G][G][G][C][C][U][A] = 2.000;
+ int22_ar[C][G][G][G][C][G][U][A] = 2.000;
+ int22_ar[C][G][G][G][C][U][U][A] = 2.000;
+ int22_ar[C][G][G][G][G][A][U][A] = 0.400;
+ int22_ar[C][G][G][G][G][C][U][A] = 2.000;
+ int22_ar[C][G][G][G][G][G][U][A] = 1.100;
+ int22_ar[C][G][G][G][G][U][U][A] = 1.200;
+ int22_ar[C][G][G][G][U][A][U][A] = 0.000;
+ int22_ar[C][G][G][G][U][C][U][A] = 2.000;
+ int22_ar[C][G][G][G][U][G][U][A] = 0.000;
+ int22_ar[C][G][G][G][U][U][U][A] = -2.000;
+ int22_ar[C][G][G][U][A][A][U][A] = 2.000;
+ int22_ar[C][G][G][U][A][C][U][A] = 2.000;
+ int22_ar[C][G][G][U][A][G][U][A] = 2.000;
+ int22_ar[C][G][G][U][A][U][U][A] = 2.000;
+ int22_ar[C][G][G][U][C][A][U][A] = 1.700;
+ int22_ar[C][G][G][U][C][C][U][A] = 2.000;
+ int22_ar[C][G][G][U][C][G][U][A] = 2.100;
+ int22_ar[C][G][G][U][C][U][U][A] = 1.500;
+ int22_ar[C][G][G][U][G][A][U][A] = 1.300;
+ int22_ar[C][G][G][U][G][C][U][A] = 2.000;
+ int22_ar[C][G][G][U][G][G][U][A] = 1.200;
+ int22_ar[C][G][G][U][G][U][U][A] = -0.700;
+ int22_ar[C][G][G][U][U][A][U][A] = 2.000;
+ int22_ar[C][G][G][U][U][C][U][A] = 2.000;
+ int22_ar[C][G][G][U][U][G][U][A] = 1.900;
+ int22_ar[C][G][G][U][U][U][U][A] = 1.800;
+ int22_ar[C][G][U][A][A][A][U][A] = 2.000;
+ int22_ar[C][G][U][A][A][C][U][A] = 2.700;
+ int22_ar[C][G][U][A][A][G][U][A] = 0.300;
+ int22_ar[C][G][U][A][A][U][U][A] = 2.200;
+ int22_ar[C][G][U][A][C][A][U][A] = 2.000;
+ int22_ar[C][G][U][A][C][C][U][A] = 1.600;
+ int22_ar[C][G][U][A][C][G][U][A] = -1.100;
+ int22_ar[C][G][U][A][C][U][U][A] = 0.700;
+ int22_ar[C][G][U][A][G][A][U][A] = 2.000;
+ int22_ar[C][G][U][A][G][C][U][A] = 2.000;
+ int22_ar[C][G][U][A][G][G][U][A] = 0.100;
+ int22_ar[C][G][U][A][G][U][U][A] = 1.900;
+ int22_ar[C][G][U][A][U][A][U][A] = 2.000;
+ int22_ar[C][G][U][A][U][C][U][A] = 2.000;
+ int22_ar[C][G][U][A][U][G][U][A] = 2.000;
+ int22_ar[C][G][U][A][U][U][U][A] = 2.000;
+ int22_ar[C][G][U][C][A][A][U][A] = 2.000;
+ int22_ar[C][G][U][C][A][C][U][A] = 2.100;
+ int22_ar[C][G][U][C][A][G][U][A] = -0.700;
+ int22_ar[C][G][U][C][A][U][U][A] = 1.200;
+ int22_ar[C][G][U][C][C][A][U][A] = 2.000;
+ int22_ar[C][G][U][C][C][C][U][A] = 2.100;
+ int22_ar[C][G][U][C][C][G][U][A] = 0.300;
+ int22_ar[C][G][U][C][C][U][U][A] = 1.200;
+ int22_ar[C][G][U][C][G][A][U][A] = 2.000;
+ int22_ar[C][G][U][C][G][C][U][A] = 2.000;
+ int22_ar[C][G][U][C][G][G][U][A] = 2.000;
+ int22_ar[C][G][U][C][G][U][U][A] = 2.000;
+ int22_ar[C][G][U][C][U][A][U][A] = 2.000;
+ int22_ar[C][G][U][C][U][C][U][A] = 2.100;
+ int22_ar[C][G][U][C][U][G][U][A] = 0.300;
+ int22_ar[C][G][U][C][U][U][U][A] = 1.200;
+ int22_ar[C][G][U][G][A][A][U][A] = 2.000;
+ int22_ar[C][G][U][G][A][C][U][A] = 2.000;
+ int22_ar[C][G][U][G][A][G][U][A] = 0.100;
+ int22_ar[C][G][U][G][A][U][U][A] = 1.900;
+ int22_ar[C][G][U][G][C][A][U][A] = 2.000;
+ int22_ar[C][G][U][G][C][C][U][A] = 2.000;
+ int22_ar[C][G][U][G][C][G][U][A] = 2.000;
+ int22_ar[C][G][U][G][C][U][U][A] = 2.000;
+ int22_ar[C][G][U][G][G][A][U][A] = 2.000;
+ int22_ar[C][G][U][G][G][C][U][A] = 2.000;
+ int22_ar[C][G][U][G][G][G][U][A] = -0.300;
+ int22_ar[C][G][U][G][G][U][U][A] = 1.500;
+ int22_ar[C][G][U][G][U][A][U][A] = 2.000;
+ int22_ar[C][G][U][G][U][C][U][A] = 0.300;
+ int22_ar[C][G][U][G][U][G][U][A] = -3.500;
+ int22_ar[C][G][U][G][U][U][U][A] = 0.200;
+ int22_ar[C][G][U][U][A][A][U][A] = 2.000;
+ int22_ar[C][G][U][U][A][C][U][A] = 2.000;
+ int22_ar[C][G][U][U][A][G][U][A] = 2.000;
+ int22_ar[C][G][U][U][A][U][U][A] = 2.000;
+ int22_ar[C][G][U][U][C][A][U][A] = 2.000;
+ int22_ar[C][G][U][U][C][C][U][A] = 1.800;
+ int22_ar[C][G][U][U][C][G][U][A] = 0.000;
+ int22_ar[C][G][U][U][C][U][U][A] = 0.900;
+ int22_ar[C][G][U][U][G][A][U][A] = 2.000;
+ int22_ar[C][G][U][U][G][C][U][A] = 1.500;
+ int22_ar[C][G][U][U][G][G][U][A] = -2.200;
+ int22_ar[C][G][U][U][G][U][U][A] = 1.500;
+ int22_ar[C][G][U][U][U][A][U][A] = 2.000;
+ int22_ar[C][G][U][U][U][C][U][A] = 1.200;
+ int22_ar[C][G][U][U][U][G][U][A] = 0.300;
+ int22_ar[C][G][U][U][U][U][U][A] = 0.300;
+ int22_ar[C][G][A][A][A][A][U][G] = 2.000;
+ int22_ar[C][G][A][A][A][C][U][G] = 2.400;
+ int22_ar[C][G][A][A][A][G][U][G] = 1.000;
+ int22_ar[C][G][A][A][A][U][U][G] = 2.000;
+ int22_ar[C][G][A][A][C][A][U][G] = 1.600;
+ int22_ar[C][G][A][A][C][C][U][G] = 1.900;
+ int22_ar[C][G][A][A][C][G][U][G] = 0.600;
+ int22_ar[C][G][A][A][C][U][U][G] = 2.000;
+ int22_ar[C][G][A][A][G][A][U][G] = 1.000;
+ int22_ar[C][G][A][A][G][C][U][G] = 1.300;
+ int22_ar[C][G][A][A][G][G][U][G] = 0.000;
+ int22_ar[C][G][A][A][G][U][U][G] = 2.000;
+ int22_ar[C][G][A][A][U][A][U][G] = 2.000;
+ int22_ar[C][G][A][A][U][C][U][G] = 2.000;
+ int22_ar[C][G][A][A][U][G][U][G] = 2.000;
+ int22_ar[C][G][A][A][U][U][U][G] = 2.000;
+ int22_ar[C][G][A][C][A][A][U][G] = 2.000;
+ int22_ar[C][G][A][C][A][C][U][G] = 2.400;
+ int22_ar[C][G][A][C][A][G][U][G] = 1.000;
+ int22_ar[C][G][A][C][A][U][U][G] = 2.000;
+ int22_ar[C][G][A][C][C][A][U][G] = 2.600;
+ int22_ar[C][G][A][C][C][C][U][G] = 2.400;
+ int22_ar[C][G][A][C][C][G][U][G] = 2.000;
+ int22_ar[C][G][A][C][C][U][U][G] = 2.000;
+ int22_ar[C][G][A][C][G][A][U][G] = 2.000;
+ int22_ar[C][G][A][C][G][C][U][G] = 2.000;
+ int22_ar[C][G][A][C][G][G][U][G] = 2.000;
+ int22_ar[C][G][A][C][G][U][U][G] = 2.000;
+ int22_ar[C][G][A][C][U][A][U][G] = 2.600;
+ int22_ar[C][G][A][C][U][C][U][G] = 2.400;
+ int22_ar[C][G][A][C][U][G][U][G] = 2.000;
+ int22_ar[C][G][A][C][U][U][U][G] = 2.000;
+ int22_ar[C][G][A][G][A][A][U][G] = 1.000;
+ int22_ar[C][G][A][G][A][C][U][G] = 1.300;
+ int22_ar[C][G][A][G][A][G][U][G] = 0.000;
+ int22_ar[C][G][A][G][A][U][U][G] = 2.000;
+ int22_ar[C][G][A][G][C][A][U][G] = 2.000;
+ int22_ar[C][G][A][G][C][C][U][G] = 2.000;
+ int22_ar[C][G][A][G][C][G][U][G] = 2.000;
+ int22_ar[C][G][A][G][C][U][U][G] = 2.000;
+ int22_ar[C][G][A][G][G][A][U][G] = 1.400;
+ int22_ar[C][G][A][G][G][C][U][G] = 1.700;
+ int22_ar[C][G][A][G][G][G][U][G] = 0.400;
+ int22_ar[C][G][A][G][G][U][U][G] = 2.000;
+ int22_ar[C][G][A][G][U][A][U][G] = 0.200;
+ int22_ar[C][G][A][G][U][C][U][G] = -0.400;
+ int22_ar[C][G][A][G][U][G][U][G] = 0.000;
+ int22_ar[C][G][A][G][U][U][U][G] = 2.000;
+ int22_ar[C][G][A][U][A][A][U][G] = 2.000;
+ int22_ar[C][G][A][U][A][C][U][G] = 2.000;
+ int22_ar[C][G][A][U][A][G][U][G] = 2.000;
+ int22_ar[C][G][A][U][A][U][U][G] = 2.000;
+ int22_ar[C][G][A][U][C][A][U][G] = 2.300;
+ int22_ar[C][G][A][U][C][C][U][G] = 2.100;
+ int22_ar[C][G][A][U][C][G][U][G] = 1.700;
+ int22_ar[C][G][A][U][C][U][U][G] = 2.000;
+ int22_ar[C][G][A][U][G][A][U][G] = 1.500;
+ int22_ar[C][G][A][U][G][C][U][G] = 0.800;
+ int22_ar[C][G][A][U][G][G][U][G] = 1.300;
+ int22_ar[C][G][A][U][G][U][U][G] = 2.000;
+ int22_ar[C][G][A][U][U][A][U][G] = 2.200;
+ int22_ar[C][G][A][U][U][C][U][G] = 1.500;
+ int22_ar[C][G][A][U][U][G][U][G] = 2.000;
+ int22_ar[C][G][A][U][U][U][U][G] = 2.000;
+ int22_ar[C][G][C][A][A][A][U][G] = 1.900;
+ int22_ar[C][G][C][A][A][C][U][G] = 2.800;
+ int22_ar[C][G][C][A][A][G][U][G] = 2.000;
+ int22_ar[C][G][C][A][A][U][U][G] = 2.700;
+ int22_ar[C][G][C][A][C][A][U][G] = 1.500;
+ int22_ar[C][G][C][A][C][C][U][G] = 1.800;
+ int22_ar[C][G][C][A][C][G][U][G] = 2.000;
+ int22_ar[C][G][C][A][C][U][U][G] = 1.600;
+ int22_ar[C][G][C][A][G][A][U][G] = 0.900;
+ int22_ar[C][G][C][A][G][C][U][G] = 2.200;
+ int22_ar[C][G][C][A][G][G][U][G] = 2.000;
+ int22_ar[C][G][C][A][G][U][U][G] = 2.000;
+ int22_ar[C][G][C][A][U][A][U][G] = 2.000;
+ int22_ar[C][G][C][A][U][C][U][G] = 2.000;
+ int22_ar[C][G][C][A][U][G][U][G] = 2.000;
+ int22_ar[C][G][C][A][U][U][U][G] = 2.000;
+ int22_ar[C][G][C][C][A][A][U][G] = 1.900;
+ int22_ar[C][G][C][C][A][C][U][G] = 2.200;
+ int22_ar[C][G][C][C][A][G][U][G] = 2.000;
+ int22_ar[C][G][C][C][A][U][U][G] = 2.100;
+ int22_ar[C][G][C][C][C][A][U][G] = 1.900;
+ int22_ar[C][G][C][C][C][C][U][G] = 2.200;
+ int22_ar[C][G][C][C][C][G][U][G] = 2.000;
+ int22_ar[C][G][C][C][C][U][U][G] = 2.100;
+ int22_ar[C][G][C][C][G][A][U][G] = 2.000;
+ int22_ar[C][G][C][C][G][C][U][G] = 2.000;
+ int22_ar[C][G][C][C][G][G][U][G] = 2.000;
+ int22_ar[C][G][C][C][G][U][U][G] = 2.000;
+ int22_ar[C][G][C][C][U][A][U][G] = 1.900;
+ int22_ar[C][G][C][C][U][C][U][G] = 2.200;
+ int22_ar[C][G][C][C][U][G][U][G] = 2.000;
+ int22_ar[C][G][C][C][U][U][U][G] = 2.100;
+ int22_ar[C][G][C][G][A][A][U][G] = 0.900;
+ int22_ar[C][G][C][G][A][C][U][G] = 2.200;
+ int22_ar[C][G][C][G][A][G][U][G] = 2.000;
+ int22_ar[C][G][C][G][A][U][U][G] = 2.000;
+ int22_ar[C][G][C][G][C][A][U][G] = 2.000;
+ int22_ar[C][G][C][G][C][C][U][G] = 2.000;
+ int22_ar[C][G][C][G][C][G][U][G] = 2.000;
+ int22_ar[C][G][C][G][C][U][U][G] = 2.000;
+ int22_ar[C][G][C][G][G][A][U][G] = 1.300;
+ int22_ar[C][G][C][G][G][C][U][G] = 2.200;
+ int22_ar[C][G][C][G][G][G][U][G] = 2.000;
+ int22_ar[C][G][C][G][G][U][U][G] = 2.000;
+ int22_ar[C][G][C][G][U][A][U][G] = -0.900;
+ int22_ar[C][G][C][G][U][C][U][G] = 0.400;
+ int22_ar[C][G][C][G][U][G][U][G] = 2.000;
+ int22_ar[C][G][C][G][U][U][U][G] = 0.300;
+ int22_ar[C][G][C][U][A][A][U][G] = 2.000;
+ int22_ar[C][G][C][U][A][C][U][G] = 2.000;
+ int22_ar[C][G][C][U][A][G][U][G] = 2.000;
+ int22_ar[C][G][C][U][A][U][U][G] = 2.000;
+ int22_ar[C][G][C][U][C][A][U][G] = 1.600;
+ int22_ar[C][G][C][U][C][C][U][G] = 1.900;
+ int22_ar[C][G][C][U][C][G][U][G] = 2.000;
+ int22_ar[C][G][C][U][C][U][U][G] = 1.800;
+ int22_ar[C][G][C][U][G][A][U][G] = 0.400;
+ int22_ar[C][G][C][U][G][C][U][G] = 1.700;
+ int22_ar[C][G][C][U][G][G][U][G] = 2.000;
+ int22_ar[C][G][C][U][G][U][U][G] = 1.500;
+ int22_ar[C][G][C][U][U][A][U][G] = 1.100;
+ int22_ar[C][G][C][U][U][C][U][G] = 1.400;
+ int22_ar[C][G][C][U][U][G][U][G] = 2.000;
+ int22_ar[C][G][C][U][U][U][U][G] = 1.200;
+ int22_ar[C][G][G][A][A][A][U][G] = 1.000;
+ int22_ar[C][G][G][A][A][C][U][G] = 2.000;
+ int22_ar[C][G][G][A][A][G][U][G] = 1.800;
+ int22_ar[C][G][G][A][A][U][U][G] = 1.800;
+ int22_ar[C][G][G][A][C][A][U][G] = 0.600;
+ int22_ar[C][G][G][A][C][C][U][G] = 2.000;
+ int22_ar[C][G][G][A][C][G][U][G] = 1.300;
+ int22_ar[C][G][G][A][C][U][U][G] = 0.400;
+ int22_ar[C][G][G][A][G][A][U][G] = 0.000;
+ int22_ar[C][G][G][A][G][C][U][G] = 2.000;
+ int22_ar[C][G][G][A][G][G][U][G] = 0.700;
+ int22_ar[C][G][G][A][G][U][U][G] = 1.600;
+ int22_ar[C][G][G][A][U][A][U][G] = 2.000;
+ int22_ar[C][G][G][A][U][C][U][G] = 2.000;
+ int22_ar[C][G][G][A][U][G][U][G] = 2.000;
+ int22_ar[C][G][G][A][U][U][U][G] = 2.000;
+ int22_ar[C][G][G][C][A][A][U][G] = 1.000;
+ int22_ar[C][G][G][C][A][C][U][G] = 2.000;
+ int22_ar[C][G][G][C][A][G][U][G] = 1.800;
+ int22_ar[C][G][G][C][A][U][U][G] = 0.800;
+ int22_ar[C][G][G][C][C][A][U][G] = 2.000;
+ int22_ar[C][G][G][C][C][C][U][G] = 2.000;
+ int22_ar[C][G][G][C][C][G][U][G] = 2.400;
+ int22_ar[C][G][G][C][C][U][U][G] = 1.800;
+ int22_ar[C][G][G][C][G][A][U][G] = 2.000;
+ int22_ar[C][G][G][C][G][C][U][G] = 2.000;
+ int22_ar[C][G][G][C][G][G][U][G] = 2.000;
+ int22_ar[C][G][G][C][G][U][U][G] = 2.000;
+ int22_ar[C][G][G][C][U][A][U][G] = 2.000;
+ int22_ar[C][G][G][C][U][C][U][G] = 2.000;
+ int22_ar[C][G][G][C][U][G][U][G] = 2.400;
+ int22_ar[C][G][G][C][U][U][U][G] = 1.800;
+ int22_ar[C][G][G][G][A][A][U][G] = 0.000;
+ int22_ar[C][G][G][G][A][C][U][G] = 2.000;
+ int22_ar[C][G][G][G][A][G][U][G] = 0.700;
+ int22_ar[C][G][G][G][A][U][U][G] = 1.600;
+ int22_ar[C][G][G][G][C][A][U][G] = 2.000;
+ int22_ar[C][G][G][G][C][C][U][G] = 2.000;
+ int22_ar[C][G][G][G][C][G][U][G] = 2.000;
+ int22_ar[C][G][G][G][C][U][U][G] = 2.000;
+ int22_ar[C][G][G][G][G][A][U][G] = 0.400;
+ int22_ar[C][G][G][G][G][C][U][G] = 2.000;
+ int22_ar[C][G][G][G][G][G][U][G] = 1.100;
+ int22_ar[C][G][G][G][G][U][U][G] = 1.200;
+ int22_ar[C][G][G][G][U][A][U][G] = 0.000;
+ int22_ar[C][G][G][G][U][C][U][G] = 2.000;
+ int22_ar[C][G][G][G][U][G][U][G] = 0.000;
+ int22_ar[C][G][G][G][U][U][U][G] = -2.000;
+ int22_ar[C][G][G][U][A][A][U][G] = 2.000;
+ int22_ar[C][G][G][U][A][C][U][G] = 2.000;
+ int22_ar[C][G][G][U][A][G][U][G] = 2.000;
+ int22_ar[C][G][G][U][A][U][U][G] = 2.000;
+ int22_ar[C][G][G][U][C][A][U][G] = 1.700;
+ int22_ar[C][G][G][U][C][C][U][G] = 2.000;
+ int22_ar[C][G][G][U][C][G][U][G] = 2.100;
+ int22_ar[C][G][G][U][C][U][U][G] = 1.500;
+ int22_ar[C][G][G][U][G][A][U][G] = 1.300;
+ int22_ar[C][G][G][U][G][C][U][G] = 2.000;
+ int22_ar[C][G][G][U][G][G][U][G] = 1.200;
+ int22_ar[C][G][G][U][G][U][U][G] = -0.700;
+ int22_ar[C][G][G][U][U][A][U][G] = 2.000;
+ int22_ar[C][G][G][U][U][C][U][G] = 2.000;
+ int22_ar[C][G][G][U][U][G][U][G] = 1.900;
+ int22_ar[C][G][G][U][U][U][U][G] = 1.800;
+ int22_ar[C][G][U][A][A][A][U][G] = 2.000;
+ int22_ar[C][G][U][A][A][C][U][G] = 2.700;
+ int22_ar[C][G][U][A][A][G][U][G] = 0.300;
+ int22_ar[C][G][U][A][A][U][U][G] = 2.200;
+ int22_ar[C][G][U][A][C][A][U][G] = 2.000;
+ int22_ar[C][G][U][A][C][C][U][G] = 1.600;
+ int22_ar[C][G][U][A][C][G][U][G] = -1.100;
+ int22_ar[C][G][U][A][C][U][U][G] = 0.700;
+ int22_ar[C][G][U][A][G][A][U][G] = 2.000;
+ int22_ar[C][G][U][A][G][C][U][G] = 2.000;
+ int22_ar[C][G][U][A][G][G][U][G] = 0.100;
+ int22_ar[C][G][U][A][G][U][U][G] = 1.900;
+ int22_ar[C][G][U][A][U][A][U][G] = 2.000;
+ int22_ar[C][G][U][A][U][C][U][G] = 2.000;
+ int22_ar[C][G][U][A][U][G][U][G] = 2.000;
+ int22_ar[C][G][U][A][U][U][U][G] = 2.000;
+ int22_ar[C][G][U][C][A][A][U][G] = 2.000;
+ int22_ar[C][G][U][C][A][C][U][G] = 2.100;
+ int22_ar[C][G][U][C][A][G][U][G] = -0.700;
+ int22_ar[C][G][U][C][A][U][U][G] = 1.200;
+ int22_ar[C][G][U][C][C][A][U][G] = 2.000;
+ int22_ar[C][G][U][C][C][C][U][G] = 2.100;
+ int22_ar[C][G][U][C][C][G][U][G] = 0.300;
+ int22_ar[C][G][U][C][C][U][U][G] = 1.200;
+ int22_ar[C][G][U][C][G][A][U][G] = 2.000;
+ int22_ar[C][G][U][C][G][C][U][G] = 2.000;
+ int22_ar[C][G][U][C][G][G][U][G] = 2.000;
+ int22_ar[C][G][U][C][G][U][U][G] = 2.000;
+ int22_ar[C][G][U][C][U][A][U][G] = 2.000;
+ int22_ar[C][G][U][C][U][C][U][G] = 2.100;
+ int22_ar[C][G][U][C][U][G][U][G] = 0.300;
+ int22_ar[C][G][U][C][U][U][U][G] = 1.200;
+ int22_ar[C][G][U][G][A][A][U][G] = 2.000;
+ int22_ar[C][G][U][G][A][C][U][G] = 2.000;
+ int22_ar[C][G][U][G][A][G][U][G] = 0.100;
+ int22_ar[C][G][U][G][A][U][U][G] = 1.900;
+ int22_ar[C][G][U][G][C][A][U][G] = 2.000;
+ int22_ar[C][G][U][G][C][C][U][G] = 2.000;
+ int22_ar[C][G][U][G][C][G][U][G] = 2.000;
+ int22_ar[C][G][U][G][C][U][U][G] = 2.000;
+ int22_ar[C][G][U][G][G][A][U][G] = 2.000;
+ int22_ar[C][G][U][G][G][C][U][G] = 2.000;
+ int22_ar[C][G][U][G][G][G][U][G] = -0.300;
+ int22_ar[C][G][U][G][G][U][U][G] = 1.500;
+ int22_ar[C][G][U][G][U][A][U][G] = 2.000;
+ int22_ar[C][G][U][G][U][C][U][G] = 0.300;
+ int22_ar[C][G][U][G][U][G][U][G] = -3.500;
+ int22_ar[C][G][U][G][U][U][U][G] = 0.200;
+ int22_ar[C][G][U][U][A][A][U][G] = 2.000;
+ int22_ar[C][G][U][U][A][C][U][G] = 2.000;
+ int22_ar[C][G][U][U][A][G][U][G] = 2.000;
+ int22_ar[C][G][U][U][A][U][U][G] = 2.000;
+ int22_ar[C][G][U][U][C][A][U][G] = 2.000;
+ int22_ar[C][G][U][U][C][C][U][G] = 1.800;
+ int22_ar[C][G][U][U][C][G][U][G] = 0.000;
+ int22_ar[C][G][U][U][C][U][U][G] = 0.900;
+ int22_ar[C][G][U][U][G][A][U][G] = 2.000;
+ int22_ar[C][G][U][U][G][C][U][G] = 1.500;
+ int22_ar[C][G][U][U][G][G][U][G] = -2.200;
+ int22_ar[C][G][U][U][G][U][U][G] = 1.500;
+ int22_ar[C][G][U][U][U][A][U][G] = 2.000;
+ int22_ar[C][G][U][U][U][C][U][G] = 1.200;
+ int22_ar[C][G][U][U][U][G][U][G] = 0.300;
+ int22_ar[C][G][U][U][U][U][U][G] = 0.300;
+ int22_ar[G][C][A][A][A][A][A][U] = 2.100;
+ int22_ar[G][C][A][A][A][C][A][U] = 1.800;
+ int22_ar[G][C][A][A][A][G][A][U] = 0.700;
+ int22_ar[G][C][A][A][A][U][A][U] = 2.000;
+ int22_ar[G][C][A][A][C][A][A][U] = 1.900;
+ int22_ar[G][C][A][A][C][C][A][U] = 1.600;
+ int22_ar[G][C][A][A][C][G][A][U] = 0.500;
+ int22_ar[G][C][A][A][C][U][A][U] = 2.000;
+ int22_ar[G][C][A][A][G][A][A][U] = 0.900;
+ int22_ar[G][C][A][A][G][C][A][U] = 0.600;
+ int22_ar[G][C][A][A][G][G][A][U] = -0.500;
+ int22_ar[G][C][A][A][G][U][A][U] = 2.000;
+ int22_ar[G][C][A][A][U][A][A][U] = 2.000;
+ int22_ar[G][C][A][A][U][C][A][U] = 2.000;
+ int22_ar[G][C][A][A][U][G][A][U] = 2.000;
+ int22_ar[G][C][A][A][U][U][A][U] = 2.000;
+ int22_ar[G][C][A][C][A][A][A][U] = 2.000;
+ int22_ar[G][C][A][C][A][C][A][U] = 1.700;
+ int22_ar[G][C][A][C][A][G][A][U] = 0.600;
+ int22_ar[G][C][A][C][A][U][A][U] = 2.000;
+ int22_ar[G][C][A][C][C][A][A][U] = 2.400;
+ int22_ar[G][C][A][C][C][C][A][U] = 1.500;
+ int22_ar[G][C][A][C][C][G][A][U] = 1.400;
+ int22_ar[G][C][A][C][C][U][A][U] = 2.000;
+ int22_ar[G][C][A][C][G][A][A][U] = 2.000;
+ int22_ar[G][C][A][C][G][C][A][U] = 2.000;
+ int22_ar[G][C][A][C][G][G][A][U] = 2.000;
+ int22_ar[G][C][A][C][G][U][A][U] = 2.000;
+ int22_ar[G][C][A][C][U][A][A][U] = 2.400;
+ int22_ar[G][C][A][C][U][C][A][U] = 1.500;
+ int22_ar[G][C][A][C][U][G][A][U] = 1.400;
+ int22_ar[G][C][A][C][U][U][A][U] = 2.000;
+ int22_ar[G][C][A][G][A][A][A][U] = 0.900;
+ int22_ar[G][C][A][G][A][C][A][U] = 0.600;
+ int22_ar[G][C][A][G][A][G][A][U] = -0.500;
+ int22_ar[G][C][A][G][A][U][A][U] = 2.000;
+ int22_ar[G][C][A][G][C][A][A][U] = 2.000;
+ int22_ar[G][C][A][G][C][C][A][U] = 2.000;
+ int22_ar[G][C][A][G][C][G][A][U] = 2.000;
+ int22_ar[G][C][A][G][C][U][A][U] = 2.000;
+ int22_ar[G][C][A][G][G][A][A][U] = 1.400;
+ int22_ar[G][C][A][G][G][C][A][U] = 1.100;
+ int22_ar[G][C][A][G][G][G][A][U] = 0.000;
+ int22_ar[G][C][A][G][G][U][A][U] = 2.000;
+ int22_ar[G][C][A][G][U][A][A][U] = 0.700;
+ int22_ar[G][C][A][G][U][C][A][U] = -0.600;
+ int22_ar[G][C][A][G][U][G][A][U] = 0.100;
+ int22_ar[G][C][A][G][U][U][A][U] = 2.000;
+ int22_ar[G][C][A][U][A][A][A][U] = 2.000;
+ int22_ar[G][C][A][U][A][C][A][U] = 2.000;
+ int22_ar[G][C][A][U][A][G][A][U] = 2.000;
+ int22_ar[G][C][A][U][A][U][A][U] = 2.000;
+ int22_ar[G][C][A][U][C][A][A][U] = 2.400;
+ int22_ar[G][C][A][U][C][C][A][U] = 1.500;
+ int22_ar[G][C][A][U][C][G][A][U] = 1.400;
+ int22_ar[G][C][A][U][C][U][A][U] = 2.000;
+ int22_ar[G][C][A][U][G][A][A][U] = 1.700;
+ int22_ar[G][C][A][U][G][C][A][U] = 0.400;
+ int22_ar[G][C][A][U][G][G][A][U] = 1.100;
+ int22_ar[G][C][A][U][G][U][A][U] = 2.000;
+ int22_ar[G][C][A][U][U][A][A][U] = 2.000;
+ int22_ar[G][C][A][U][U][C][A][U] = 0.700;
+ int22_ar[G][C][A][U][U][G][A][U] = 1.500;
+ int22_ar[G][C][A][U][U][U][A][U] = 2.000;
+ int22_ar[G][C][C][A][A][A][A][U] = 1.900;
+ int22_ar[G][C][C][A][A][C][A][U] = 2.500;
+ int22_ar[G][C][C][A][A][G][A][U] = 2.000;
+ int22_ar[G][C][C][A][A][U][A][U] = 2.500;
+ int22_ar[G][C][C][A][C][A][A][U] = 1.600;
+ int22_ar[G][C][C][A][C][C][A][U] = 1.600;
+ int22_ar[G][C][C][A][C][G][A][U] = 2.000;
+ int22_ar[G][C][C][A][C][U][A][U] = 1.700;
+ int22_ar[G][C][C][A][G][A][A][U] = 0.600;
+ int22_ar[G][C][C][A][G][C][A][U] = 1.600;
+ int22_ar[G][C][C][A][G][G][A][U] = 2.000;
+ int22_ar[G][C][C][A][G][U][A][U] = 1.700;
+ int22_ar[G][C][C][A][U][A][A][U] = 2.000;
+ int22_ar[G][C][C][A][U][C][A][U] = 2.000;
+ int22_ar[G][C][C][A][U][G][A][U] = 2.000;
+ int22_ar[G][C][C][A][U][U][A][U] = 2.000;
+ int22_ar[G][C][C][C][A][A][A][U] = 1.700;
+ int22_ar[G][C][C][C][A][C][A][U] = 1.700;
+ int22_ar[G][C][C][C][A][G][A][U] = 2.000;
+ int22_ar[G][C][C][C][A][U][A][U] = 1.800;
+ int22_ar[G][C][C][C][C][A][A][U] = 1.600;
+ int22_ar[G][C][C][C][C][C][A][U] = 1.600;
+ int22_ar[G][C][C][C][C][G][A][U] = 2.000;
+ int22_ar[G][C][C][C][C][U][A][U] = 1.600;
+ int22_ar[G][C][C][C][G][A][A][U] = 2.000;
+ int22_ar[G][C][C][C][G][C][A][U] = 2.000;
+ int22_ar[G][C][C][C][G][G][A][U] = 2.000;
+ int22_ar[G][C][C][C][G][U][A][U] = 2.000;
+ int22_ar[G][C][C][C][U][A][A][U] = 1.600;
+ int22_ar[G][C][C][C][U][C][A][U] = 1.600;
+ int22_ar[G][C][C][C][U][G][A][U] = 2.000;
+ int22_ar[G][C][C][C][U][U][A][U] = 1.600;
+ int22_ar[G][C][C][G][A][A][A][U] = 0.600;
+ int22_ar[G][C][C][G][A][C][A][U] = 1.600;
+ int22_ar[G][C][C][G][A][G][A][U] = 2.000;
+ int22_ar[G][C][C][G][A][U][A][U] = 1.700;
+ int22_ar[G][C][C][G][C][A][A][U] = 2.000;
+ int22_ar[G][C][C][G][C][C][A][U] = 2.000;
+ int22_ar[G][C][C][G][C][G][A][U] = 2.000;
+ int22_ar[G][C][C][G][C][U][A][U] = 2.000;
+ int22_ar[G][C][C][G][G][A][A][U] = 1.200;
+ int22_ar[G][C][C][G][G][C][A][U] = 1.800;
+ int22_ar[G][C][C][G][G][G][A][U] = 2.000;
+ int22_ar[G][C][C][G][G][U][A][U] = 1.800;
+ int22_ar[G][C][C][G][U][A][A][U] = -0.500;
+ int22_ar[G][C][C][G][U][C][A][U] = 0.500;
+ int22_ar[G][C][C][G][U][G][A][U] = 2.000;
+ int22_ar[G][C][C][G][U][U][A][U] = 0.500;
+ int22_ar[G][C][C][U][A][A][A][U] = 2.000;
+ int22_ar[G][C][C][U][A][C][A][U] = 2.000;
+ int22_ar[G][C][C][U][A][G][A][U] = 2.000;
+ int22_ar[G][C][C][U][A][U][A][U] = 2.000;
+ int22_ar[G][C][C][U][C][A][A][U] = 1.600;
+ int22_ar[G][C][C][U][C][C][A][U] = 1.600;
+ int22_ar[G][C][C][U][C][G][A][U] = 2.000;
+ int22_ar[G][C][C][U][C][U][A][U] = 1.600;
+ int22_ar[G][C][C][U][G][A][A][U] = 0.400;
+ int22_ar[G][C][C][U][G][C][A][U] = 1.400;
+ int22_ar[G][C][C][U][G][G][A][U] = 2.000;
+ int22_ar[G][C][C][U][G][U][A][U] = 1.500;
+ int22_ar[G][C][C][U][U][A][A][U] = 0.800;
+ int22_ar[G][C][C][U][U][C][A][U] = 0.800;
+ int22_ar[G][C][C][U][U][G][A][U] = 2.000;
+ int22_ar[G][C][C][U][U][U][A][U] = 0.800;
+ int22_ar[G][C][G][A][A][A][A][U] = 0.100;
+ int22_ar[G][C][G][A][A][C][A][U] = 2.000;
+ int22_ar[G][C][G][A][A][G][A][U] = 1.800;
+ int22_ar[G][C][G][A][A][U][A][U] = 0.400;
+ int22_ar[G][C][G][A][C][A][A][U] = -0.100;
+ int22_ar[G][C][G][A][C][C][A][U] = 2.000;
+ int22_ar[G][C][G][A][C][G][A][U] = 1.500;
+ int22_ar[G][C][G][A][C][U][A][U] = -0.900;
+ int22_ar[G][C][G][A][G][A][A][U] = -1.100;
+ int22_ar[G][C][G][A][G][C][A][U] = 2.000;
+ int22_ar[G][C][G][A][G][G][A][U] = 0.500;
+ int22_ar[G][C][G][A][G][U][A][U] = -0.100;
+ int22_ar[G][C][G][A][U][A][A][U] = 2.000;
+ int22_ar[G][C][G][A][U][C][A][U] = 2.000;
+ int22_ar[G][C][G][A][U][G][A][U] = 2.000;
+ int22_ar[G][C][G][A][U][U][A][U] = 2.000;
+ int22_ar[G][C][G][C][A][A][A][U] = 0.000;
+ int22_ar[G][C][G][C][A][C][A][U] = 2.000;
+ int22_ar[G][C][G][C][A][G][A][U] = 1.600;
+ int22_ar[G][C][G][C][A][U][A][U] = -0.800;
+ int22_ar[G][C][G][C][C][A][A][U] = 0.800;
+ int22_ar[G][C][G][C][C][C][A][U] = 2.000;
+ int22_ar[G][C][G][C][C][G][A][U] = 2.100;
+ int22_ar[G][C][G][C][C][U][A][U] = 0.100;
+ int22_ar[G][C][G][C][G][A][A][U] = 2.000;
+ int22_ar[G][C][G][C][G][C][A][U] = 2.000;
+ int22_ar[G][C][G][C][G][G][A][U] = 2.000;
+ int22_ar[G][C][G][C][G][U][A][U] = 2.000;
+ int22_ar[G][C][G][C][U][A][A][U] = 0.800;
+ int22_ar[G][C][G][C][U][C][A][U] = 2.000;
+ int22_ar[G][C][G][C][U][G][A][U] = 2.100;
+ int22_ar[G][C][G][C][U][U][A][U] = 0.100;
+ int22_ar[G][C][G][G][A][A][A][U] = -1.100;
+ int22_ar[G][C][G][G][A][C][A][U] = 2.000;
+ int22_ar[G][C][G][G][A][G][A][U] = 0.500;
+ int22_ar[G][C][G][G][A][U][A][U] = -0.100;
+ int22_ar[G][C][G][G][C][A][A][U] = 2.000;
+ int22_ar[G][C][G][G][C][C][A][U] = 2.000;
+ int22_ar[G][C][G][G][C][G][A][U] = 2.000;
+ int22_ar[G][C][G][G][C][U][A][U] = 2.000;
+ int22_ar[G][C][G][G][G][A][A][U] = -0.600;
+ int22_ar[G][C][G][G][G][C][A][U] = 2.000;
+ int22_ar[G][C][G][G][G][G][A][U] = 1.100;
+ int22_ar[G][C][G][G][G][U][A][U] = -0.300;
+ int22_ar[G][C][G][G][U][A][A][U] = -0.500;
+ int22_ar[G][C][G][G][U][C][A][U] = 2.000;
+ int22_ar[G][C][G][G][U][G][A][U] = 0.400;
+ int22_ar[G][C][G][G][U][U][A][U] = -3.100;
+ int22_ar[G][C][G][U][A][A][A][U] = 2.000;
+ int22_ar[G][C][G][U][A][C][A][U] = 2.000;
+ int22_ar[G][C][G][U][A][G][A][U] = 2.000;
+ int22_ar[G][C][G][U][A][U][A][U] = 2.000;
+ int22_ar[G][C][G][U][C][A][A][U] = 0.800;
+ int22_ar[G][C][G][U][C][C][A][U] = 2.000;
+ int22_ar[G][C][G][U][C][G][A][U] = 2.100;
+ int22_ar[G][C][G][U][C][U][A][U] = 0.100;
+ int22_ar[G][C][G][U][G][A][A][U] = 0.500;
+ int22_ar[G][C][G][U][G][C][A][U] = 2.000;
+ int22_ar[G][C][G][U][G][G][A][U] = 1.300;
+ int22_ar[G][C][G][U][G][U][A][U] = -2.100;
+ int22_ar[G][C][G][U][U][A][A][U] = 0.800;
+ int22_ar[G][C][G][U][U][C][A][U] = 2.000;
+ int22_ar[G][C][G][U][U][G][A][U] = 1.700;
+ int22_ar[G][C][G][U][U][U][A][U] = 0.100;
+ int22_ar[G][C][U][A][A][A][A][U] = 2.000;
+ int22_ar[G][C][U][A][A][C][A][U] = 1.500;
+ int22_ar[G][C][U][A][A][G][A][U] = 0.000;
+ int22_ar[G][C][U][A][A][U][A][U] = 2.100;
+ int22_ar[G][C][U][A][C][A][A][U] = 2.000;
+ int22_ar[G][C][U][A][C][C][A][U] = 0.600;
+ int22_ar[G][C][U][A][C][G][A][U] = -1.300;
+ int22_ar[G][C][U][A][C][U][A][U] = 0.900;
+ int22_ar[G][C][U][A][G][A][A][U] = 2.000;
+ int22_ar[G][C][U][A][G][C][A][U] = 0.700;
+ int22_ar[G][C][U][A][G][G][A][U] = -0.500;
+ int22_ar[G][C][U][A][G][U][A][U] = 1.700;
+ int22_ar[G][C][U][A][U][A][A][U] = 2.000;
+ int22_ar[G][C][U][A][U][C][A][U] = 2.000;
+ int22_ar[G][C][U][A][U][G][A][U] = 2.000;
+ int22_ar[G][C][U][A][U][U][A][U] = 2.000;
+ int22_ar[G][C][U][C][A][A][A][U] = 2.000;
+ int22_ar[G][C][U][C][A][C][A][U] = 0.700;
+ int22_ar[G][C][U][C][A][G][A][U] = -1.200;
+ int22_ar[G][C][U][C][A][U][A][U] = 1.000;
+ int22_ar[G][C][U][C][C][A][A][U] = 2.000;
+ int22_ar[G][C][U][C][C][C][A][U] = 0.600;
+ int22_ar[G][C][U][C][C][G][A][U] = -0.300;
+ int22_ar[G][C][U][C][C][U][A][U] = 0.800;
+ int22_ar[G][C][U][C][G][A][A][U] = 2.000;
+ int22_ar[G][C][U][C][G][C][A][U] = 2.000;
+ int22_ar[G][C][U][C][G][G][A][U] = 2.000;
+ int22_ar[G][C][U][C][G][U][A][U] = 2.000;
+ int22_ar[G][C][U][C][U][A][A][U] = 2.000;
+ int22_ar[G][C][U][C][U][C][A][U] = 0.600;
+ int22_ar[G][C][U][C][U][G][A][U] = -0.300;
+ int22_ar[G][C][U][C][U][U][A][U] = 0.800;
+ int22_ar[G][C][U][G][A][A][A][U] = 2.000;
+ int22_ar[G][C][U][G][A][C][A][U] = 0.700;
+ int22_ar[G][C][U][G][A][G][A][U] = -0.500;
+ int22_ar[G][C][U][G][A][U][A][U] = 1.700;
+ int22_ar[G][C][U][G][C][A][A][U] = 2.000;
+ int22_ar[G][C][U][G][C][C][A][U] = 2.000;
+ int22_ar[G][C][U][G][C][G][A][U] = 2.000;
+ int22_ar[G][C][U][G][C][U][A][U] = 2.000;
+ int22_ar[G][C][U][G][G][A][A][U] = 2.000;
+ int22_ar[G][C][U][G][G][C][A][U] = 0.800;
+ int22_ar[G][C][U][G][G][G][A][U] = -0.700;
+ int22_ar[G][C][U][G][G][U][A][U] = 1.400;
+ int22_ar[G][C][U][G][U][A][A][U] = 2.000;
+ int22_ar[G][C][U][G][U][C][A][U] = -0.500;
+ int22_ar[G][C][U][G][U][G][A][U] = -3.500;
+ int22_ar[G][C][U][G][U][U][A][U] = 0.500;
+ int22_ar[G][C][U][U][A][A][A][U] = 2.000;
+ int22_ar[G][C][U][U][A][C][A][U] = 2.000;
+ int22_ar[G][C][U][U][A][G][A][U] = 2.000;
+ int22_ar[G][C][U][U][A][U][A][U] = 2.000;
+ int22_ar[G][C][U][U][C][A][A][U] = 2.000;
+ int22_ar[G][C][U][U][C][C][A][U] = 0.600;
+ int22_ar[G][C][U][U][C][G][A][U] = -0.300;
+ int22_ar[G][C][U][U][C][U][A][U] = 0.800;
+ int22_ar[G][C][U][U][G][A][A][U] = 2.000;
+ int22_ar[G][C][U][U][G][C][A][U] = 0.500;
+ int22_ar[G][C][U][U][G][G][A][U] = -2.500;
+ int22_ar[G][C][U][U][G][U][A][U] = 1.500;
+ int22_ar[G][C][U][U][U][A][A][U] = 2.000;
+ int22_ar[G][C][U][U][U][C][A][U] = -0.200;
+ int22_ar[G][C][U][U][U][G][A][U] = -0.300;
+ int22_ar[G][C][U][U][U][U][A][U] = 0.000;
+ int22_ar[G][C][A][A][A][A][C][G] = 0.500;
+ int22_ar[G][C][A][A][A][C][C][G] = 1.100;
+ int22_ar[G][C][A][A][A][G][C][G] = 0.400;
+ int22_ar[G][C][A][A][A][U][C][G] = 2.000;
+ int22_ar[G][C][A][A][C][A][C][G] = 1.300;
+ int22_ar[G][C][A][A][C][C][C][G] = 1.000;
+ int22_ar[G][C][A][A][C][G][C][G] = 0.700;
+ int22_ar[G][C][A][A][C][U][C][G] = 2.000;
+ int22_ar[G][C][A][A][G][A][C][G] = -0.200;
+ int22_ar[G][C][A][A][G][C][C][G] = 0.700;
+ int22_ar[G][C][A][A][G][G][C][G] = -0.500;
+ int22_ar[G][C][A][A][G][U][C][G] = 2.000;
+ int22_ar[G][C][A][A][U][A][C][G] = 2.000;
+ int22_ar[G][C][A][A][U][C][C][G] = 2.000;
+ int22_ar[G][C][A][A][U][G][C][G] = 2.000;
+ int22_ar[G][C][A][A][U][U][C][G] = 2.000;
+ int22_ar[G][C][A][C][A][A][C][G] = 0.600;
+ int22_ar[G][C][A][C][A][C][C][G] = 1.100;
+ int22_ar[G][C][A][C][A][G][C][G] = 0.500;
+ int22_ar[G][C][A][C][A][U][C][G] = 2.000;
+ int22_ar[G][C][A][C][C][A][C][G] = 2.200;
+ int22_ar[G][C][A][C][C][C][C][G] = 1.900;
+ int22_ar[G][C][A][C][C][G][C][G] = 0.700;
+ int22_ar[G][C][A][C][C][U][C][G] = 2.000;
+ int22_ar[G][C][A][C][G][A][C][G] = 2.000;
+ int22_ar[G][C][A][C][G][C][C][G] = 2.000;
+ int22_ar[G][C][A][C][G][G][C][G] = 2.000;
+ int22_ar[G][C][A][C][G][U][C][G] = 2.000;
+ int22_ar[G][C][A][C][U][A][C][G] = 2.000;
+ int22_ar[G][C][A][C][U][C][C][G] = 1.100;
+ int22_ar[G][C][A][C][U][G][C][G] = 0.500;
+ int22_ar[G][C][A][C][U][U][C][G] = 2.000;
+ int22_ar[G][C][A][G][A][A][C][G] = 0.000;
+ int22_ar[G][C][A][G][A][C][C][G] = -1.000;
+ int22_ar[G][C][A][G][A][G][C][G] = -0.700;
+ int22_ar[G][C][A][G][A][U][C][G] = 2.000;
+ int22_ar[G][C][A][G][C][A][C][G] = 2.000;
+ int22_ar[G][C][A][G][C][C][C][G] = 2.000;
+ int22_ar[G][C][A][G][C][G][C][G] = 2.000;
+ int22_ar[G][C][A][G][C][U][C][G] = 2.000;
+ int22_ar[G][C][A][G][G][A][C][G] = 1.100;
+ int22_ar[G][C][A][G][G][C][C][G] = 0.800;
+ int22_ar[G][C][A][G][G][G][C][G] = -0.200;
+ int22_ar[G][C][A][G][G][U][C][G] = 2.000;
+ int22_ar[G][C][A][G][U][A][C][G] = -0.100;
+ int22_ar[G][C][A][G][U][C][C][G] = -1.600;
+ int22_ar[G][C][A][G][U][G][C][G] = -0.600;
+ int22_ar[G][C][A][G][U][U][C][G] = 2.000;
+ int22_ar[G][C][A][U][A][A][C][G] = 2.000;
+ int22_ar[G][C][A][U][A][C][C][G] = 2.000;
+ int22_ar[G][C][A][U][A][G][C][G] = 2.000;
+ int22_ar[G][C][A][U][A][U][C][G] = 2.000;
+ int22_ar[G][C][A][U][C][A][C][G] = 2.000;
+ int22_ar[G][C][A][U][C][C][C][G] = 1.100;
+ int22_ar[G][C][A][U][C][G][C][G] = 1.000;
+ int22_ar[G][C][A][U][C][U][C][G] = 2.000;
+ int22_ar[G][C][A][U][G][A][C][G] = 0.900;
+ int22_ar[G][C][A][U][G][C][C][G] = -0.100;
+ int22_ar[G][C][A][U][G][G][C][G] = 0.600;
+ int22_ar[G][C][A][U][G][U][C][G] = 2.000;
+ int22_ar[G][C][A][U][U][A][C][G] = 1.400;
+ int22_ar[G][C][A][U][U][C][C][G] = 0.300;
+ int22_ar[G][C][A][U][U][G][C][G] = 1.400;
+ int22_ar[G][C][A][U][U][U][C][G] = 2.000;
+ int22_ar[G][C][C][A][A][A][C][G] = 1.100;
+ int22_ar[G][C][C][A][A][C][C][G] = 1.700;
+ int22_ar[G][C][C][A][A][G][C][G] = 2.000;
+ int22_ar[G][C][C][A][A][U][C][G] = 1.800;
+ int22_ar[G][C][C][A][C][A][C][G] = 1.000;
+ int22_ar[G][C][C][A][C][C][C][G] = 1.000;
+ int22_ar[G][C][C][A][C][G][C][G] = 2.000;
+ int22_ar[G][C][C][A][C][U][C][G] = 1.100;
+ int22_ar[G][C][C][A][G][A][C][G] = -0.400;
+ int22_ar[G][C][C][A][G][C][C][G] = 1.100;
+ int22_ar[G][C][C][A][G][G][C][G] = 2.000;
+ int22_ar[G][C][C][A][G][U][C][G] = 1.200;
+ int22_ar[G][C][C][A][U][A][C][G] = 2.000;
+ int22_ar[G][C][C][A][U][C][C][G] = 2.000;
+ int22_ar[G][C][C][A][U][G][C][G] = 2.000;
+ int22_ar[G][C][C][A][U][U][C][G] = 2.000;
+ int22_ar[G][C][C][C][A][A][C][G] = 1.500;
+ int22_ar[G][C][C][C][A][C][C][G] = 1.500;
+ int22_ar[G][C][C][C][A][G][C][G] = 2.000;
+ int22_ar[G][C][C][C][A][U][C][G] = 1.500;
+ int22_ar[G][C][C][C][C][A][C][G] = 1.300;
+ int22_ar[G][C][C][C][C][C][C][G] = 1.300;
+ int22_ar[G][C][C][C][C][G][C][G] = 2.000;
+ int22_ar[G][C][C][C][C][U][C][G] = 1.400;
+ int22_ar[G][C][C][C][G][A][C][G] = 2.000;
+ int22_ar[G][C][C][C][G][C][C][G] = 2.000;
+ int22_ar[G][C][C][C][G][G][C][G] = 2.000;
+ int22_ar[G][C][C][C][G][U][C][G] = 2.000;
+ int22_ar[G][C][C][C][U][A][C][G] = 1.200;
+ int22_ar[G][C][C][C][U][C][C][G] = 1.200;
+ int22_ar[G][C][C][C][U][G][C][G] = 2.000;
+ int22_ar[G][C][C][C][U][U][C][G] = 1.200;
+ int22_ar[G][C][C][G][A][A][C][G] = -0.700;
+ int22_ar[G][C][C][G][A][C][C][G] = -0.600;
+ int22_ar[G][C][C][G][A][G][C][G] = 2.000;
+ int22_ar[G][C][C][G][A][U][C][G] = 1.200;
+ int22_ar[G][C][C][G][C][A][C][G] = 2.000;
+ int22_ar[G][C][C][G][C][C][C][G] = 2.000;
+ int22_ar[G][C][C][G][C][G][C][G] = 2.000;
+ int22_ar[G][C][C][G][C][U][C][G] = 2.000;
+ int22_ar[G][C][C][G][G][A][C][G] = 0.900;
+ int22_ar[G][C][C][G][G][C][C][G] = 1.500;
+ int22_ar[G][C][C][G][G][G][C][G] = 2.000;
+ int22_ar[G][C][C][G][G][U][C][G] = 1.500;
+ int22_ar[G][C][C][G][U][A][C][G] = -1.600;
+ int22_ar[G][C][C][G][U][C][C][G] = -0.600;
+ int22_ar[G][C][C][G][U][G][C][G] = 2.000;
+ int22_ar[G][C][C][G][U][U][C][G] = -0.500;
+ int22_ar[G][C][C][U][A][A][C][G] = 2.000;
+ int22_ar[G][C][C][U][A][C][C][G] = 2.000;
+ int22_ar[G][C][C][U][A][G][C][G] = 2.000;
+ int22_ar[G][C][C][U][A][U][C][G] = 2.000;
+ int22_ar[G][C][C][U][C][A][C][G] = 1.200;
+ int22_ar[G][C][C][U][C][C][C][G] = 1.200;
+ int22_ar[G][C][C][U][C][G][C][G] = 2.000;
+ int22_ar[G][C][C][U][C][U][C][G] = 1.200;
+ int22_ar[G][C][C][U][G][A][C][G] = 0.000;
+ int22_ar[G][C][C][U][G][C][C][G] = 1.000;
+ int22_ar[G][C][C][U][G][G][C][G] = 2.000;
+ int22_ar[G][C][C][U][G][U][C][G] = 1.000;
+ int22_ar[G][C][C][U][U][A][C][G] = 0.300;
+ int22_ar[G][C][C][U][U][C][C][G] = 0.300;
+ int22_ar[G][C][C][U][U][G][C][G] = 2.000;
+ int22_ar[G][C][C][U][U][U][C][G] = 0.300;
+ int22_ar[G][C][G][A][A][A][C][G] = -0.300;
+ int22_ar[G][C][G][A][A][C][C][G] = 2.000;
+ int22_ar[G][C][G][A][A][G][C][G] = 1.000;
+ int22_ar[G][C][G][A][A][U][C][G] = -0.500;
+ int22_ar[G][C][G][A][C][A][C][G] = -0.700;
+ int22_ar[G][C][G][A][C][C][C][G] = 2.000;
+ int22_ar[G][C][G][A][C][G][C][G] = 0.900;
+ int22_ar[G][C][G][A][C][U][C][G] = -1.500;
+ int22_ar[G][C][G][A][G][A][C][G] = -1.700;
+ int22_ar[G][C][G][A][G][C][C][G] = 2.000;
+ int22_ar[G][C][G][A][G][G][C][G] = 0.000;
+ int22_ar[G][C][G][A][G][U][C][G] = -1.300;
+ int22_ar[G][C][G][A][U][A][C][G] = 2.000;
+ int22_ar[G][C][G][A][U][C][C][G] = 2.000;
+ int22_ar[G][C][G][A][U][G][C][G] = 2.000;
+ int22_ar[G][C][G][A][U][U][C][G] = 2.000;
+ int22_ar[G][C][G][C][A][A][C][G] = 0.100;
+ int22_ar[G][C][G][C][A][C][C][G] = 2.000;
+ int22_ar[G][C][G][C][A][G][C][G] = 1.400;
+ int22_ar[G][C][G][C][A][U][C][G] = -0.600;
+ int22_ar[G][C][G][C][C][A][C][G] = 0.700;
+ int22_ar[G][C][G][C][C][C][C][G] = 2.000;
+ int22_ar[G][C][G][C][C][G][C][G] = 1.800;
+ int22_ar[G][C][G][C][C][U][C][G] = -0.200;
+ int22_ar[G][C][G][C][G][A][C][G] = 2.000;
+ int22_ar[G][C][G][C][G][C][C][G] = 2.000;
+ int22_ar[G][C][G][C][G][G][C][G] = 2.000;
+ int22_ar[G][C][G][C][G][U][C][G] = 2.000;
+ int22_ar[G][C][G][C][U][A][C][G] = 0.400;
+ int22_ar[G][C][G][C][U][C][C][G] = 2.000;
+ int22_ar[G][C][G][C][U][G][C][G] = 1.700;
+ int22_ar[G][C][G][C][U][U][C][G] = -0.100;
+ int22_ar[G][C][G][G][A][A][C][G] = -1.600;
+ int22_ar[G][C][G][G][A][C][C][G] = 2.000;
+ int22_ar[G][C][G][G][A][G][C][G] = 0.000;
+ int22_ar[G][C][G][G][A][U][C][G] = -0.600;
+ int22_ar[G][C][G][G][C][A][C][G] = 2.000;
+ int22_ar[G][C][G][G][C][C][C][G] = 2.000;
+ int22_ar[G][C][G][G][C][G][C][G] = 2.000;
+ int22_ar[G][C][G][G][C][U][C][G] = 2.000;
+ int22_ar[G][C][G][G][G][A][C][G] = -0.900;
+ int22_ar[G][C][G][G][G][C][C][G] = 2.000;
+ int22_ar[G][C][G][G][G][G][C][G] = 0.800;
+ int22_ar[G][C][G][G][G][U][C][G] = -0.600;
+ int22_ar[G][C][G][G][U][A][C][G] = -1.600;
+ int22_ar[G][C][G][G][U][C][C][G] = 2.000;
+ int22_ar[G][C][G][G][U][G][C][G] = -0.700;
+ int22_ar[G][C][G][G][U][U][C][G] = -4.100;
+ int22_ar[G][C][G][U][A][A][C][G] = 2.000;
+ int22_ar[G][C][G][U][A][C][C][G] = 2.000;
+ int22_ar[G][C][G][U][A][G][C][G] = 2.000;
+ int22_ar[G][C][G][U][A][U][C][G] = 2.000;
+ int22_ar[G][C][G][U][C][A][C][G] = 0.400;
+ int22_ar[G][C][G][U][C][C][C][G] = 2.000;
+ int22_ar[G][C][G][U][C][G][C][G] = 1.700;
+ int22_ar[G][C][G][U][C][U][C][G] = -0.300;
+ int22_ar[G][C][G][U][G][A][C][G] = 0.300;
+ int22_ar[G][C][G][U][G][C][C][G] = 2.000;
+ int22_ar[G][C][G][U][G][G][C][G] = 0.900;
+ int22_ar[G][C][G][U][G][U][C][G] = -2.400;
+ int22_ar[G][C][G][U][U][A][C][G] = 0.500;
+ int22_ar[G][C][G][U][U][C][C][G] = 2.000;
+ int22_ar[G][C][G][U][U][G][C][G] = 1.200;
+ int22_ar[G][C][G][U][U][U][C][G] = 0.100;
+ int22_ar[G][C][U][A][A][A][C][G] = 2.000;
+ int22_ar[G][C][U][A][A][C][C][G] = 0.700;
+ int22_ar[G][C][U][A][A][G][C][G] = 0.100;
+ int22_ar[G][C][U][A][A][U][C][G] = 1.500;
+ int22_ar[G][C][U][A][C][A][C][G] = 2.000;
+ int22_ar[G][C][U][A][C][C][C][G] = 0.000;
+ int22_ar[G][C][U][A][C][G][C][G] = -1.900;
+ int22_ar[G][C][U][A][C][U][C][G] = -0.200;
+ int22_ar[G][C][U][A][G][A][C][G] = 2.000;
+ int22_ar[G][C][U][A][G][C][C][G] = 0.200;
+ int22_ar[G][C][U][A][G][G][C][G] = -0.900;
+ int22_ar[G][C][U][A][G][U][C][G] = 0.900;
+ int22_ar[G][C][U][A][U][A][C][G] = 2.000;
+ int22_ar[G][C][U][A][U][C][C][G] = 2.000;
+ int22_ar[G][C][U][A][U][G][C][G] = 2.000;
+ int22_ar[G][C][U][A][U][U][C][G] = 2.000;
+ int22_ar[G][C][U][C][A][A][C][G] = 2.000;
+ int22_ar[G][C][U][C][A][C][C][G] = 0.500;
+ int22_ar[G][C][U][C][A][G][C][G] = -0.700;
+ int22_ar[G][C][U][C][A][U][C][G] = 0.000;
+ int22_ar[G][C][U][C][C][A][C][G] = 2.000;
+ int22_ar[G][C][U][C][C][C][C][G] = 0.300;
+ int22_ar[G][C][U][C][C][G][C][G] = -0.300;
+ int22_ar[G][C][U][C][C][U][C][G] = -0.100;
+ int22_ar[G][C][U][C][G][A][C][G] = 2.000;
+ int22_ar[G][C][U][C][G][C][C][G] = 2.000;
+ int22_ar[G][C][U][C][G][G][C][G] = 2.000;
+ int22_ar[G][C][U][C][G][U][C][G] = 2.000;
+ int22_ar[G][C][U][C][U][A][C][G] = 2.000;
+ int22_ar[G][C][U][C][U][C][C][G] = 0.200;
+ int22_ar[G][C][U][C][U][G][C][G] = -0.700;
+ int22_ar[G][C][U][C][U][U][C][G] = 0.400;
+ int22_ar[G][C][U][G][A][A][C][G] = 2.000;
+ int22_ar[G][C][U][G][A][C][C][G] = 0.200;
+ int22_ar[G][C][U][G][A][G][C][G] = -0.800;
+ int22_ar[G][C][U][G][A][U][C][G] = 0.900;
+ int22_ar[G][C][U][G][C][A][C][G] = 2.000;
+ int22_ar[G][C][U][G][C][C][C][G] = 2.000;
+ int22_ar[G][C][U][G][C][G][C][G] = 2.000;
+ int22_ar[G][C][U][G][C][U][C][G] = 2.000;
+ int22_ar[G][C][U][G][G][A][C][G] = 2.000;
+ int22_ar[G][C][U][G][G][C][C][G] = 0.500;
+ int22_ar[G][C][U][G][G][G][C][G] = -1.000;
+ int22_ar[G][C][U][G][G][U][C][G] = 1.100;
+ int22_ar[G][C][U][G][U][A][C][G] = 2.000;
+ int22_ar[G][C][U][G][U][C][C][G] = -1.600;
+ int22_ar[G][C][U][G][U][G][C][G] = -4.400;
+ int22_ar[G][C][U][G][U][U][C][G] = -1.000;
+ int22_ar[G][C][U][U][A][A][C][G] = 2.000;
+ int22_ar[G][C][U][U][A][C][C][G] = 2.000;
+ int22_ar[G][C][U][U][A][G][C][G] = 2.000;
+ int22_ar[G][C][U][U][A][U][C][G] = 2.000;
+ int22_ar[G][C][U][U][C][A][C][G] = 2.000;
+ int22_ar[G][C][U][U][C][C][C][G] = 1.700;
+ int22_ar[G][C][U][U][C][G][C][G] = -0.700;
+ int22_ar[G][C][U][U][C][U][C][G] = 0.200;
+ int22_ar[G][C][U][U][G][A][C][G] = 2.000;
+ int22_ar[G][C][U][U][G][C][C][G] = 0.000;
+ int22_ar[G][C][U][U][G][G][C][G] = -3.000;
+ int22_ar[G][C][U][U][G][U][C][G] = 0.600;
+ int22_ar[G][C][U][U][U][A][C][G] = 2.000;
+ int22_ar[G][C][U][U][U][C][C][G] = 0.100;
+ int22_ar[G][C][U][U][U][G][C][G] = -1.000;
+ int22_ar[G][C][U][U][U][U][C][G] = 0.600;
+ int22_ar[G][C][A][A][A][A][G][C] = 1.500;
+ int22_ar[G][C][A][A][A][C][G][C] = 1.200;
+ int22_ar[G][C][A][A][A][G][G][C] = 0.100;
+ int22_ar[G][C][A][A][A][U][G][C] = 2.000;
+ int22_ar[G][C][A][A][C][A][G][C] = 1.200;
+ int22_ar[G][C][A][A][C][C][G][C] = 0.900;
+ int22_ar[G][C][A][A][C][G][G][C] = -0.100;
+ int22_ar[G][C][A][A][C][U][G][C] = 2.000;
+ int22_ar[G][C][A][A][G][A][G][C] = -0.500;
+ int22_ar[G][C][A][A][G][C][G][C] = -0.800;
+ int22_ar[G][C][A][A][G][G][G][C] = -1.900;
+ int22_ar[G][C][A][A][G][U][G][C] = 2.000;
+ int22_ar[G][C][A][A][U][A][G][C] = 2.000;
+ int22_ar[G][C][A][A][U][C][G][C] = 2.000;
+ int22_ar[G][C][A][A][U][G][G][C] = 2.000;
+ int22_ar[G][C][A][A][U][U][G][C] = 2.000;
+ int22_ar[G][C][A][C][A][A][G][C] = 1.200;
+ int22_ar[G][C][A][C][A][C][G][C] = 0.900;
+ int22_ar[G][C][A][C][A][G][G][C] = -0.200;
+ int22_ar[G][C][A][C][A][U][G][C] = 2.000;
+ int22_ar[G][C][A][C][C][A][G][C] = 1.800;
+ int22_ar[G][C][A][C][C][C][G][C] = 0.900;
+ int22_ar[G][C][A][C][C][G][G][C] = 0.900;
+ int22_ar[G][C][A][C][C][U][G][C] = 2.000;
+ int22_ar[G][C][A][C][G][A][G][C] = 2.000;
+ int22_ar[G][C][A][C][G][C][G][C] = 2.000;
+ int22_ar[G][C][A][C][G][G][G][C] = 2.000;
+ int22_ar[G][C][A][C][G][U][G][C] = 2.000;
+ int22_ar[G][C][A][C][U][A][G][C] = 0.800;
+ int22_ar[G][C][A][C][U][C][G][C] = 0.000;
+ int22_ar[G][C][A][C][U][G][G][C] = -0.100;
+ int22_ar[G][C][A][C][U][U][G][C] = 2.000;
+ int22_ar[G][C][A][G][A][A][G][C] = 0.100;
+ int22_ar[G][C][A][G][A][C][G][C] = -0.200;
+ int22_ar[G][C][A][G][A][G][G][C] = -1.300;
+ int22_ar[G][C][A][G][A][U][G][C] = 2.000;
+ int22_ar[G][C][A][G][C][A][G][C] = 2.000;
+ int22_ar[G][C][A][G][C][C][G][C] = 2.000;
+ int22_ar[G][C][A][G][C][G][G][C] = 2.000;
+ int22_ar[G][C][A][G][C][U][G][C] = 2.000;
+ int22_ar[G][C][A][G][G][A][G][C] = 1.100;
+ int22_ar[G][C][A][G][G][C][G][C] = 0.800;
+ int22_ar[G][C][A][G][G][G][G][C] = -0.200;
+ int22_ar[G][C][A][G][G][U][G][C] = 2.000;
+ int22_ar[G][C][A][G][U][A][G][C] = -0.700;
+ int22_ar[G][C][A][G][U][C][G][C] = -2.000;
+ int22_ar[G][C][A][G][U][G][G][C] = -1.300;
+ int22_ar[G][C][A][G][U][U][G][C] = 2.000;
+ int22_ar[G][C][A][U][A][A][G][C] = 2.000;
+ int22_ar[G][C][A][U][A][C][G][C] = 2.000;
+ int22_ar[G][C][A][U][A][G][G][C] = 2.000;
+ int22_ar[G][C][A][U][A][U][G][C] = 2.000;
+ int22_ar[G][C][A][U][C][A][G][C] = 1.900;
+ int22_ar[G][C][A][U][C][C][G][C] = 1.000;
+ int22_ar[G][C][A][U][C][G][G][C] = 0.900;
+ int22_ar[G][C][A][U][C][U][G][C] = 2.000;
+ int22_ar[G][C][A][U][G][A][G][C] = -0.300;
+ int22_ar[G][C][A][U][G][C][G][C] = -1.600;
+ int22_ar[G][C][A][U][G][G][G][C] = -0.900;
+ int22_ar[G][C][A][U][G][U][G][C] = 2.000;
+ int22_ar[G][C][A][U][U][A][G][C] = 1.500;
+ int22_ar[G][C][A][U][U][C][G][C] = 0.200;
+ int22_ar[G][C][A][U][U][G][G][C] = 0.900;
+ int22_ar[G][C][A][U][U][U][G][C] = 2.000;
+ int22_ar[G][C][C][A][A][A][G][C] = 1.200;
+ int22_ar[G][C][C][A][A][C][G][C] = 1.800;
+ int22_ar[G][C][C][A][A][G][G][C] = 2.000;
+ int22_ar[G][C][C][A][A][U][G][C] = 1.900;
+ int22_ar[G][C][C][A][C][A][G][C] = 1.000;
+ int22_ar[G][C][C][A][C][C][G][C] = 1.000;
+ int22_ar[G][C][C][A][C][G][G][C] = 2.000;
+ int22_ar[G][C][C][A][C][U][G][C] = 1.000;
+ int22_ar[G][C][C][A][G][A][G][C] = -0.800;
+ int22_ar[G][C][C][A][G][C][G][C] = 0.200;
+ int22_ar[G][C][C][A][G][G][G][C] = 2.000;
+ int22_ar[G][C][C][A][G][U][G][C] = 0.300;
+ int22_ar[G][C][C][A][U][A][G][C] = 2.000;
+ int22_ar[G][C][C][A][U][C][G][C] = 2.000;
+ int22_ar[G][C][C][A][U][G][G][C] = 2.000;
+ int22_ar[G][C][C][A][U][U][G][C] = 2.000;
+ int22_ar[G][C][C][C][A][A][G][C] = 0.900;
+ int22_ar[G][C][C][C][A][C][G][C] = 0.900;
+ int22_ar[G][C][C][C][A][G][G][C] = 2.000;
+ int22_ar[G][C][C][C][A][U][G][C] = 1.000;
+ int22_ar[G][C][C][C][C][A][G][C] = 1.000;
+ int22_ar[G][C][C][C][C][C][G][C] = 1.000;
+ int22_ar[G][C][C][C][C][G][G][C] = 2.000;
+ int22_ar[G][C][C][C][C][U][G][C] = 1.000;
+ int22_ar[G][C][C][C][G][A][G][C] = 2.000;
+ int22_ar[G][C][C][C][G][C][G][C] = 2.000;
+ int22_ar[G][C][C][C][G][G][G][C] = 2.000;
+ int22_ar[G][C][C][C][G][U][G][C] = 2.000;
+ int22_ar[G][C][C][C][U][A][G][C] = 0.000;
+ int22_ar[G][C][C][C][U][C][G][C] = 0.000;
+ int22_ar[G][C][C][C][U][G][G][C] = 2.000;
+ int22_ar[G][C][C][C][U][U][G][C] = 0.000;
+ int22_ar[G][C][C][G][A][A][G][C] = -0.100;
+ int22_ar[G][C][C][G][A][C][G][C] = 0.900;
+ int22_ar[G][C][C][G][A][G][G][C] = 2.000;
+ int22_ar[G][C][C][G][A][U][G][C] = 0.900;
+ int22_ar[G][C][C][G][C][A][G][C] = 2.000;
+ int22_ar[G][C][C][G][C][C][G][C] = 2.000;
+ int22_ar[G][C][C][G][C][G][G][C] = 2.000;
+ int22_ar[G][C][C][G][C][U][G][C] = 2.000;
+ int22_ar[G][C][C][G][G][A][G][C] = 0.900;
+ int22_ar[G][C][C][G][G][C][G][C] = 1.500;
+ int22_ar[G][C][C][G][G][G][G][C] = 2.000;
+ int22_ar[G][C][C][G][G][U][G][C] = 1.500;
+ int22_ar[G][C][C][G][U][A][G][C] = -1.900;
+ int22_ar[G][C][C][G][U][C][G][C] = -0.900;
+ int22_ar[G][C][C][G][U][G][G][C] = 2.000;
+ int22_ar[G][C][C][G][U][U][G][C] = -0.900;
+ int22_ar[G][C][C][U][A][A][G][C] = 2.000;
+ int22_ar[G][C][C][U][A][C][G][C] = 2.000;
+ int22_ar[G][C][C][U][A][G][G][C] = 2.000;
+ int22_ar[G][C][C][U][A][U][G][C] = 2.000;
+ int22_ar[G][C][C][U][C][A][G][C] = 1.000;
+ int22_ar[G][C][C][U][C][C][G][C] = 1.000;
+ int22_ar[G][C][C][U][C][G][G][C] = 2.000;
+ int22_ar[G][C][C][U][C][U][G][C] = 1.100;
+ int22_ar[G][C][C][U][G][A][G][C] = -1.500;
+ int22_ar[G][C][C][U][G][C][G][C] = -0.500;
+ int22_ar[G][C][C][U][G][G][G][C] = 2.000;
+ int22_ar[G][C][C][U][G][U][G][C] = -0.500;
+ int22_ar[G][C][C][U][U][A][G][C] = 0.200;
+ int22_ar[G][C][C][U][U][C][G][C] = 0.200;
+ int22_ar[G][C][C][U][U][G][G][C] = 2.000;
+ int22_ar[G][C][C][U][U][U][G][C] = 0.300;
+ int22_ar[G][C][G][A][A][A][G][C] = -0.500;
+ int22_ar[G][C][G][A][A][C][G][C] = 2.000;
+ int22_ar[G][C][G][A][A][G][G][C] = 1.100;
+ int22_ar[G][C][G][A][A][U][G][C] = -0.300;
+ int22_ar[G][C][G][A][C][A][G][C] = -0.800;
+ int22_ar[G][C][G][A][C][C][G][C] = 2.000;
+ int22_ar[G][C][G][A][C][G][G][C] = 0.900;
+ int22_ar[G][C][G][A][C][U][G][C] = -1.500;
+ int22_ar[G][C][G][A][G][A][G][C] = -2.600;
+ int22_ar[G][C][G][A][G][C][G][C] = 2.000;
+ int22_ar[G][C][G][A][G][G][G][C] = -0.900;
+ int22_ar[G][C][G][A][G][U][G][C] = -1.500;
+ int22_ar[G][C][G][A][U][A][G][C] = 2.000;
+ int22_ar[G][C][G][A][U][C][G][C] = 2.000;
+ int22_ar[G][C][G][A][U][G][G][C] = 2.000;
+ int22_ar[G][C][G][A][U][U][G][C] = 2.000;
+ int22_ar[G][C][G][C][A][A][G][C] = -0.800;
+ int22_ar[G][C][G][C][A][C][G][C] = 2.000;
+ int22_ar[G][C][G][C][A][G][G][C] = 0.800;
+ int22_ar[G][C][G][C][A][U][G][C] = -1.600;
+ int22_ar[G][C][G][C][C][A][G][C] = 0.200;
+ int22_ar[G][C][G][C][C][C][G][C] = 2.000;
+ int22_ar[G][C][G][C][C][G][G][C] = 1.500;
+ int22_ar[G][C][G][C][C][U][G][C] = -0.500;
+ int22_ar[G][C][G][C][G][A][G][C] = 2.000;
+ int22_ar[G][C][G][C][G][C][G][C] = 2.000;
+ int22_ar[G][C][G][C][G][G][G][C] = 2.000;
+ int22_ar[G][C][G][C][G][U][G][C] = 2.000;
+ int22_ar[G][C][G][C][U][A][G][C] = -0.800;
+ int22_ar[G][C][G][C][U][C][G][C] = 2.000;
+ int22_ar[G][C][G][C][U][G][G][C] = 0.500;
+ int22_ar[G][C][G][C][U][U][G][C] = -1.500;
+ int22_ar[G][C][G][G][A][A][G][C] = -1.900;
+ int22_ar[G][C][G][G][A][C][G][C] = 2.000;
+ int22_ar[G][C][G][G][A][G][G][C] = -0.200;
+ int22_ar[G][C][G][G][A][U][G][C] = -0.900;
+ int22_ar[G][C][G][G][C][A][G][C] = 2.000;
+ int22_ar[G][C][G][G][C][C][G][C] = 2.000;
+ int22_ar[G][C][G][G][C][G][G][C] = 2.000;
+ int22_ar[G][C][G][G][C][U][G][C] = 2.000;
+ int22_ar[G][C][G][G][G][A][G][C] = -0.900;
+ int22_ar[G][C][G][G][G][C][G][C] = 2.000;
+ int22_ar[G][C][G][G][G][G][G][C] = 0.800;
+ int22_ar[G][C][G][G][G][U][G][C] = -0.600;
+ int22_ar[G][C][G][G][U][A][G][C] = -1.900;
+ int22_ar[G][C][G][G][U][C][G][C] = 2.000;
+ int22_ar[G][C][G][G][U][G][G][C] = -1.000;
+ int22_ar[G][C][G][G][U][U][G][C] = -4.500;
+ int22_ar[G][C][G][U][A][A][G][C] = 2.000;
+ int22_ar[G][C][G][U][A][C][G][C] = 2.000;
+ int22_ar[G][C][G][U][A][G][G][C] = 2.000;
+ int22_ar[G][C][G][U][A][U][G][C] = 2.000;
+ int22_ar[G][C][G][U][C][A][G][C] = 0.300;
+ int22_ar[G][C][G][U][C][C][G][C] = 2.000;
+ int22_ar[G][C][G][U][C][G][G][C] = 1.500;
+ int22_ar[G][C][G][U][C][U][G][C] = -0.500;
+ int22_ar[G][C][G][U][G][A][G][C] = -1.500;
+ int22_ar[G][C][G][U][G][C][G][C] = 2.000;
+ int22_ar[G][C][G][U][G][G][G][C] = -0.600;
+ int22_ar[G][C][G][U][G][U][G][C] = -4.100;
+ int22_ar[G][C][G][U][U][A][G][C] = 0.300;
+ int22_ar[G][C][G][U][U][C][G][C] = 2.000;
+ int22_ar[G][C][G][U][U][G][G][C] = 1.100;
+ int22_ar[G][C][G][U][U][U][G][C] = -0.500;
+ int22_ar[G][C][U][A][A][A][G][C] = 2.000;
+ int22_ar[G][C][U][A][A][C][G][C] = 0.800;
+ int22_ar[G][C][U][A][A][G][G][C] = -0.700;
+ int22_ar[G][C][U][A][A][U][G][C] = 1.500;
+ int22_ar[G][C][U][A][C][A][G][C] = 2.000;
+ int22_ar[G][C][U][A][C][C][G][C] = 0.000;
+ int22_ar[G][C][U][A][C][G][G][C] = -1.900;
+ int22_ar[G][C][U][A][C][U][G][C] = 0.200;
+ int22_ar[G][C][U][A][G][A][G][C] = 2.000;
+ int22_ar[G][C][U][A][G][C][G][C] = -0.800;
+ int22_ar[G][C][U][A][G][G][G][C] = -1.900;
+ int22_ar[G][C][U][A][G][U][G][C] = 0.300;
+ int22_ar[G][C][U][A][U][A][G][C] = 2.000;
+ int22_ar[G][C][U][A][U][C][G][C] = 2.000;
+ int22_ar[G][C][U][A][U][G][G][C] = 2.000;
+ int22_ar[G][C][U][A][U][U][G][C] = 2.000;
+ int22_ar[G][C][U][C][A][A][G][C] = 2.000;
+ int22_ar[G][C][U][C][A][C][G][C] = 0.000;
+ int22_ar[G][C][U][C][A][G][G][C] = -2.000;
+ int22_ar[G][C][U][C][A][U][G][C] = 0.200;
+ int22_ar[G][C][U][C][C][A][G][C] = 2.000;
+ int22_ar[G][C][U][C][C][C][G][C] = 0.000;
+ int22_ar[G][C][U][C][C][G][G][C] = -0.900;
+ int22_ar[G][C][U][C][C][U][G][C] = 0.200;
+ int22_ar[G][C][U][C][G][A][G][C] = 2.000;
+ int22_ar[G][C][U][C][G][C][G][C] = 2.000;
+ int22_ar[G][C][U][C][G][G][G][C] = 2.000;
+ int22_ar[G][C][U][C][G][U][G][C] = 2.000;
+ int22_ar[G][C][U][C][U][A][G][C] = 2.000;
+ int22_ar[G][C][U][C][U][C][G][C] = -1.000;
+ int22_ar[G][C][U][C][U][G][G][C] = -1.900;
+ int22_ar[G][C][U][C][U][U][G][C] = -0.700;
+ int22_ar[G][C][U][G][A][A][G][C] = 2.000;
+ int22_ar[G][C][U][G][A][C][G][C] = -0.100;
+ int22_ar[G][C][U][G][A][G][G][C] = -1.300;
+ int22_ar[G][C][U][G][A][U][G][C] = 0.900;
+ int22_ar[G][C][U][G][C][A][G][C] = 2.000;
+ int22_ar[G][C][U][G][C][C][G][C] = 2.000;
+ int22_ar[G][C][U][G][C][G][G][C] = 2.000;
+ int22_ar[G][C][U][G][C][U][G][C] = 2.000;
+ int22_ar[G][C][U][G][G][A][G][C] = 2.000;
+ int22_ar[G][C][U][G][G][C][G][C] = 0.500;
+ int22_ar[G][C][U][G][G][G][G][C] = -1.000;
+ int22_ar[G][C][U][G][G][U][G][C] = 1.100;
+ int22_ar[G][C][U][G][U][A][G][C] = 2.000;
+ int22_ar[G][C][U][G][U][C][G][C] = -1.900;
+ int22_ar[G][C][U][G][U][G][G][C] = -4.900;
+ int22_ar[G][C][U][G][U][U][G][C] = -0.900;
+ int22_ar[G][C][U][U][A][A][G][C] = 2.000;
+ int22_ar[G][C][U][U][A][C][G][C] = 2.000;
+ int22_ar[G][C][U][U][A][G][G][C] = 2.000;
+ int22_ar[G][C][U][U][A][U][G][C] = 2.000;
+ int22_ar[G][C][U][U][C][A][G][C] = 2.000;
+ int22_ar[G][C][U][U][C][C][G][C] = 0.000;
+ int22_ar[G][C][U][U][C][G][G][C] = -0.900;
+ int22_ar[G][C][U][U][C][U][G][C] = 0.300;
+ int22_ar[G][C][U][U][G][A][G][C] = 2.000;
+ int22_ar[G][C][U][U][G][C][G][C] = -1.500;
+ int22_ar[G][C][U][U][G][G][G][C] = -4.500;
+ int22_ar[G][C][U][U][G][U][G][C] = -0.500;
+ int22_ar[G][C][U][U][U][A][G][C] = 2.000;
+ int22_ar[G][C][U][U][U][C][G][C] = -0.700;
+ int22_ar[G][C][U][U][U][G][G][C] = -0.900;
+ int22_ar[G][C][U][U][U][U][G][C] = -0.500;
+ int22_ar[G][C][A][A][A][A][G][U] = 2.100;
+ int22_ar[G][C][A][A][A][C][G][U] = 1.800;
+ int22_ar[G][C][A][A][A][G][G][U] = 0.700;
+ int22_ar[G][C][A][A][A][U][G][U] = 2.000;
+ int22_ar[G][C][A][A][C][A][G][U] = 1.900;
+ int22_ar[G][C][A][A][C][C][G][U] = 1.600;
+ int22_ar[G][C][A][A][C][G][G][U] = 0.500;
+ int22_ar[G][C][A][A][C][U][G][U] = 2.000;
+ int22_ar[G][C][A][A][G][A][G][U] = 0.900;
+ int22_ar[G][C][A][A][G][C][G][U] = 0.600;
+ int22_ar[G][C][A][A][G][G][G][U] = -0.500;
+ int22_ar[G][C][A][A][G][U][G][U] = 2.000;
+ int22_ar[G][C][A][A][U][A][G][U] = 2.000;
+ int22_ar[G][C][A][A][U][C][G][U] = 2.000;
+ int22_ar[G][C][A][A][U][G][G][U] = 2.000;
+ int22_ar[G][C][A][A][U][U][G][U] = 2.000;
+ int22_ar[G][C][A][C][A][A][G][U] = 2.000;
+ int22_ar[G][C][A][C][A][C][G][U] = 1.700;
+ int22_ar[G][C][A][C][A][G][G][U] = 0.600;
+ int22_ar[G][C][A][C][A][U][G][U] = 2.000;
+ int22_ar[G][C][A][C][C][A][G][U] = 2.400;
+ int22_ar[G][C][A][C][C][C][G][U] = 1.500;
+ int22_ar[G][C][A][C][C][G][G][U] = 1.400;
+ int22_ar[G][C][A][C][C][U][G][U] = 2.000;
+ int22_ar[G][C][A][C][G][A][G][U] = 2.000;
+ int22_ar[G][C][A][C][G][C][G][U] = 2.000;
+ int22_ar[G][C][A][C][G][G][G][U] = 2.000;
+ int22_ar[G][C][A][C][G][U][G][U] = 2.000;
+ int22_ar[G][C][A][C][U][A][G][U] = 2.400;
+ int22_ar[G][C][A][C][U][C][G][U] = 1.500;
+ int22_ar[G][C][A][C][U][G][G][U] = 1.400;
+ int22_ar[G][C][A][C][U][U][G][U] = 2.000;
+ int22_ar[G][C][A][G][A][A][G][U] = 0.900;
+ int22_ar[G][C][A][G][A][C][G][U] = 0.600;
+ int22_ar[G][C][A][G][A][G][G][U] = -0.500;
+ int22_ar[G][C][A][G][A][U][G][U] = 2.000;
+ int22_ar[G][C][A][G][C][A][G][U] = 2.000;
+ int22_ar[G][C][A][G][C][C][G][U] = 2.000;
+ int22_ar[G][C][A][G][C][G][G][U] = 2.000;
+ int22_ar[G][C][A][G][C][U][G][U] = 2.000;
+ int22_ar[G][C][A][G][G][A][G][U] = 1.400;
+ int22_ar[G][C][A][G][G][C][G][U] = 1.100;
+ int22_ar[G][C][A][G][G][G][G][U] = 0.000;
+ int22_ar[G][C][A][G][G][U][G][U] = 2.000;
+ int22_ar[G][C][A][G][U][A][G][U] = 0.700;
+ int22_ar[G][C][A][G][U][C][G][U] = -0.600;
+ int22_ar[G][C][A][G][U][G][G][U] = 0.100;
+ int22_ar[G][C][A][G][U][U][G][U] = 2.000;
+ int22_ar[G][C][A][U][A][A][G][U] = 2.000;
+ int22_ar[G][C][A][U][A][C][G][U] = 2.000;
+ int22_ar[G][C][A][U][A][G][G][U] = 2.000;
+ int22_ar[G][C][A][U][A][U][G][U] = 2.000;
+ int22_ar[G][C][A][U][C][A][G][U] = 2.400;
+ int22_ar[G][C][A][U][C][C][G][U] = 1.500;
+ int22_ar[G][C][A][U][C][G][G][U] = 1.400;
+ int22_ar[G][C][A][U][C][U][G][U] = 2.000;
+ int22_ar[G][C][A][U][G][A][G][U] = 1.700;
+ int22_ar[G][C][A][U][G][C][G][U] = 0.400;
+ int22_ar[G][C][A][U][G][G][G][U] = 1.100;
+ int22_ar[G][C][A][U][G][U][G][U] = 2.000;
+ int22_ar[G][C][A][U][U][A][G][U] = 2.000;
+ int22_ar[G][C][A][U][U][C][G][U] = 0.700;
+ int22_ar[G][C][A][U][U][G][G][U] = 1.500;
+ int22_ar[G][C][A][U][U][U][G][U] = 2.000;
+ int22_ar[G][C][C][A][A][A][G][U] = 1.900;
+ int22_ar[G][C][C][A][A][C][G][U] = 2.500;
+ int22_ar[G][C][C][A][A][G][G][U] = 2.000;
+ int22_ar[G][C][C][A][A][U][G][U] = 2.500;
+ int22_ar[G][C][C][A][C][A][G][U] = 1.600;
+ int22_ar[G][C][C][A][C][C][G][U] = 1.600;
+ int22_ar[G][C][C][A][C][G][G][U] = 2.000;
+ int22_ar[G][C][C][A][C][U][G][U] = 1.700;
+ int22_ar[G][C][C][A][G][A][G][U] = 0.600;
+ int22_ar[G][C][C][A][G][C][G][U] = 1.600;
+ int22_ar[G][C][C][A][G][G][G][U] = 2.000;
+ int22_ar[G][C][C][A][G][U][G][U] = 1.700;
+ int22_ar[G][C][C][A][U][A][G][U] = 2.000;
+ int22_ar[G][C][C][A][U][C][G][U] = 2.000;
+ int22_ar[G][C][C][A][U][G][G][U] = 2.000;
+ int22_ar[G][C][C][A][U][U][G][U] = 2.000;
+ int22_ar[G][C][C][C][A][A][G][U] = 1.700;
+ int22_ar[G][C][C][C][A][C][G][U] = 1.700;
+ int22_ar[G][C][C][C][A][G][G][U] = 2.000;
+ int22_ar[G][C][C][C][A][U][G][U] = 1.800;
+ int22_ar[G][C][C][C][C][A][G][U] = 1.600;
+ int22_ar[G][C][C][C][C][C][G][U] = 1.600;
+ int22_ar[G][C][C][C][C][G][G][U] = 2.000;
+ int22_ar[G][C][C][C][C][U][G][U] = 1.600;
+ int22_ar[G][C][C][C][G][A][G][U] = 2.000;
+ int22_ar[G][C][C][C][G][C][G][U] = 2.000;
+ int22_ar[G][C][C][C][G][G][G][U] = 2.000;
+ int22_ar[G][C][C][C][G][U][G][U] = 2.000;
+ int22_ar[G][C][C][C][U][A][G][U] = 1.600;
+ int22_ar[G][C][C][C][U][C][G][U] = 1.600;
+ int22_ar[G][C][C][C][U][G][G][U] = 2.000;
+ int22_ar[G][C][C][C][U][U][G][U] = 1.600;
+ int22_ar[G][C][C][G][A][A][G][U] = 0.600;
+ int22_ar[G][C][C][G][A][C][G][U] = 1.600;
+ int22_ar[G][C][C][G][A][G][G][U] = 2.000;
+ int22_ar[G][C][C][G][A][U][G][U] = 1.700;
+ int22_ar[G][C][C][G][C][A][G][U] = 2.000;
+ int22_ar[G][C][C][G][C][C][G][U] = 2.000;
+ int22_ar[G][C][C][G][C][G][G][U] = 2.000;
+ int22_ar[G][C][C][G][C][U][G][U] = 2.000;
+ int22_ar[G][C][C][G][G][A][G][U] = 1.200;
+ int22_ar[G][C][C][G][G][C][G][U] = 1.800;
+ int22_ar[G][C][C][G][G][G][G][U] = 2.000;
+ int22_ar[G][C][C][G][G][U][G][U] = 1.800;
+ int22_ar[G][C][C][G][U][A][G][U] = -0.500;
+ int22_ar[G][C][C][G][U][C][G][U] = 0.500;
+ int22_ar[G][C][C][G][U][G][G][U] = 2.000;
+ int22_ar[G][C][C][G][U][U][G][U] = 0.500;
+ int22_ar[G][C][C][U][A][A][G][U] = 2.000;
+ int22_ar[G][C][C][U][A][C][G][U] = 2.000;
+ int22_ar[G][C][C][U][A][G][G][U] = 2.000;
+ int22_ar[G][C][C][U][A][U][G][U] = 2.000;
+ int22_ar[G][C][C][U][C][A][G][U] = 1.600;
+ int22_ar[G][C][C][U][C][C][G][U] = 1.600;
+ int22_ar[G][C][C][U][C][G][G][U] = 2.000;
+ int22_ar[G][C][C][U][C][U][G][U] = 1.600;
+ int22_ar[G][C][C][U][G][A][G][U] = 0.400;
+ int22_ar[G][C][C][U][G][C][G][U] = 1.400;
+ int22_ar[G][C][C][U][G][G][G][U] = 2.000;
+ int22_ar[G][C][C][U][G][U][G][U] = 1.500;
+ int22_ar[G][C][C][U][U][A][G][U] = 0.800;
+ int22_ar[G][C][C][U][U][C][G][U] = 0.800;
+ int22_ar[G][C][C][U][U][G][G][U] = 2.000;
+ int22_ar[G][C][C][U][U][U][G][U] = 0.800;
+ int22_ar[G][C][G][A][A][A][G][U] = 0.100;
+ int22_ar[G][C][G][A][A][C][G][U] = 2.000;
+ int22_ar[G][C][G][A][A][G][G][U] = 1.800;
+ int22_ar[G][C][G][A][A][U][G][U] = 0.400;
+ int22_ar[G][C][G][A][C][A][G][U] = -0.100;
+ int22_ar[G][C][G][A][C][C][G][U] = 2.000;
+ int22_ar[G][C][G][A][C][G][G][U] = 1.500;
+ int22_ar[G][C][G][A][C][U][G][U] = -0.900;
+ int22_ar[G][C][G][A][G][A][G][U] = -1.100;
+ int22_ar[G][C][G][A][G][C][G][U] = 2.000;
+ int22_ar[G][C][G][A][G][G][G][U] = 0.500;
+ int22_ar[G][C][G][A][G][U][G][U] = -0.100;
+ int22_ar[G][C][G][A][U][A][G][U] = 2.000;
+ int22_ar[G][C][G][A][U][C][G][U] = 2.000;
+ int22_ar[G][C][G][A][U][G][G][U] = 2.000;
+ int22_ar[G][C][G][A][U][U][G][U] = 2.000;
+ int22_ar[G][C][G][C][A][A][G][U] = 0.000;
+ int22_ar[G][C][G][C][A][C][G][U] = 2.000;
+ int22_ar[G][C][G][C][A][G][G][U] = 1.600;
+ int22_ar[G][C][G][C][A][U][G][U] = -0.800;
+ int22_ar[G][C][G][C][C][A][G][U] = 0.800;
+ int22_ar[G][C][G][C][C][C][G][U] = 2.000;
+ int22_ar[G][C][G][C][C][G][G][U] = 2.100;
+ int22_ar[G][C][G][C][C][U][G][U] = 0.100;
+ int22_ar[G][C][G][C][G][A][G][U] = 2.000;
+ int22_ar[G][C][G][C][G][C][G][U] = 2.000;
+ int22_ar[G][C][G][C][G][G][G][U] = 2.000;
+ int22_ar[G][C][G][C][G][U][G][U] = 2.000;
+ int22_ar[G][C][G][C][U][A][G][U] = 0.800;
+ int22_ar[G][C][G][C][U][C][G][U] = 2.000;
+ int22_ar[G][C][G][C][U][G][G][U] = 2.100;
+ int22_ar[G][C][G][C][U][U][G][U] = 0.100;
+ int22_ar[G][C][G][G][A][A][G][U] = -1.100;
+ int22_ar[G][C][G][G][A][C][G][U] = 2.000;
+ int22_ar[G][C][G][G][A][G][G][U] = 0.500;
+ int22_ar[G][C][G][G][A][U][G][U] = -0.100;
+ int22_ar[G][C][G][G][C][A][G][U] = 2.000;
+ int22_ar[G][C][G][G][C][C][G][U] = 2.000;
+ int22_ar[G][C][G][G][C][G][G][U] = 2.000;
+ int22_ar[G][C][G][G][C][U][G][U] = 2.000;
+ int22_ar[G][C][G][G][G][A][G][U] = -0.600;
+ int22_ar[G][C][G][G][G][C][G][U] = 2.000;
+ int22_ar[G][C][G][G][G][G][G][U] = 1.100;
+ int22_ar[G][C][G][G][G][U][G][U] = -0.300;
+ int22_ar[G][C][G][G][U][A][G][U] = -0.500;
+ int22_ar[G][C][G][G][U][C][G][U] = 2.000;
+ int22_ar[G][C][G][G][U][G][G][U] = 0.400;
+ int22_ar[G][C][G][G][U][U][G][U] = -3.100;
+ int22_ar[G][C][G][U][A][A][G][U] = 2.000;
+ int22_ar[G][C][G][U][A][C][G][U] = 2.000;
+ int22_ar[G][C][G][U][A][G][G][U] = 2.000;
+ int22_ar[G][C][G][U][A][U][G][U] = 2.000;
+ int22_ar[G][C][G][U][C][A][G][U] = 0.800;
+ int22_ar[G][C][G][U][C][C][G][U] = 2.000;
+ int22_ar[G][C][G][U][C][G][G][U] = 2.100;
+ int22_ar[G][C][G][U][C][U][G][U] = 0.100;
+ int22_ar[G][C][G][U][G][A][G][U] = 0.500;
+ int22_ar[G][C][G][U][G][C][G][U] = 2.000;
+ int22_ar[G][C][G][U][G][G][G][U] = 1.300;
+ int22_ar[G][C][G][U][G][U][G][U] = -2.100;
+ int22_ar[G][C][G][U][U][A][G][U] = 0.800;
+ int22_ar[G][C][G][U][U][C][G][U] = 2.000;
+ int22_ar[G][C][G][U][U][G][G][U] = 1.700;
+ int22_ar[G][C][G][U][U][U][G][U] = 0.100;
+ int22_ar[G][C][U][A][A][A][G][U] = 2.000;
+ int22_ar[G][C][U][A][A][C][G][U] = 1.500;
+ int22_ar[G][C][U][A][A][G][G][U] = 0.000;
+ int22_ar[G][C][U][A][A][U][G][U] = 2.100;
+ int22_ar[G][C][U][A][C][A][G][U] = 2.000;
+ int22_ar[G][C][U][A][C][C][G][U] = 0.600;
+ int22_ar[G][C][U][A][C][G][G][U] = -1.300;
+ int22_ar[G][C][U][A][C][U][G][U] = 0.900;
+ int22_ar[G][C][U][A][G][A][G][U] = 2.000;
+ int22_ar[G][C][U][A][G][C][G][U] = 0.700;
+ int22_ar[G][C][U][A][G][G][G][U] = -0.500;
+ int22_ar[G][C][U][A][G][U][G][U] = 1.700;
+ int22_ar[G][C][U][A][U][A][G][U] = 2.000;
+ int22_ar[G][C][U][A][U][C][G][U] = 2.000;
+ int22_ar[G][C][U][A][U][G][G][U] = 2.000;
+ int22_ar[G][C][U][A][U][U][G][U] = 2.000;
+ int22_ar[G][C][U][C][A][A][G][U] = 2.000;
+ int22_ar[G][C][U][C][A][C][G][U] = 0.700;
+ int22_ar[G][C][U][C][A][G][G][U] = -1.200;
+ int22_ar[G][C][U][C][A][U][G][U] = 1.000;
+ int22_ar[G][C][U][C][C][A][G][U] = 2.000;
+ int22_ar[G][C][U][C][C][C][G][U] = 0.600;
+ int22_ar[G][C][U][C][C][G][G][U] = -0.300;
+ int22_ar[G][C][U][C][C][U][G][U] = 0.800;
+ int22_ar[G][C][U][C][G][A][G][U] = 2.000;
+ int22_ar[G][C][U][C][G][C][G][U] = 2.000;
+ int22_ar[G][C][U][C][G][G][G][U] = 2.000;
+ int22_ar[G][C][U][C][G][U][G][U] = 2.000;
+ int22_ar[G][C][U][C][U][A][G][U] = 2.000;
+ int22_ar[G][C][U][C][U][C][G][U] = 0.600;
+ int22_ar[G][C][U][C][U][G][G][U] = -0.300;
+ int22_ar[G][C][U][C][U][U][G][U] = 0.800;
+ int22_ar[G][C][U][G][A][A][G][U] = 2.000;
+ int22_ar[G][C][U][G][A][C][G][U] = 0.700;
+ int22_ar[G][C][U][G][A][G][G][U] = -0.500;
+ int22_ar[G][C][U][G][A][U][G][U] = 1.700;
+ int22_ar[G][C][U][G][C][A][G][U] = 2.000;
+ int22_ar[G][C][U][G][C][C][G][U] = 2.000;
+ int22_ar[G][C][U][G][C][G][G][U] = 2.000;
+ int22_ar[G][C][U][G][C][U][G][U] = 2.000;
+ int22_ar[G][C][U][G][G][A][G][U] = 2.000;
+ int22_ar[G][C][U][G][G][C][G][U] = 0.800;
+ int22_ar[G][C][U][G][G][G][G][U] = -0.700;
+ int22_ar[G][C][U][G][G][U][G][U] = 1.400;
+ int22_ar[G][C][U][G][U][A][G][U] = 2.000;
+ int22_ar[G][C][U][G][U][C][G][U] = -0.500;
+ int22_ar[G][C][U][G][U][G][G][U] = -3.500;
+ int22_ar[G][C][U][G][U][U][G][U] = 0.500;
+ int22_ar[G][C][U][U][A][A][G][U] = 2.000;
+ int22_ar[G][C][U][U][A][C][G][U] = 2.000;
+ int22_ar[G][C][U][U][A][G][G][U] = 2.000;
+ int22_ar[G][C][U][U][A][U][G][U] = 2.000;
+ int22_ar[G][C][U][U][C][A][G][U] = 2.000;
+ int22_ar[G][C][U][U][C][C][G][U] = 0.600;
+ int22_ar[G][C][U][U][C][G][G][U] = -0.300;
+ int22_ar[G][C][U][U][C][U][G][U] = 0.800;
+ int22_ar[G][C][U][U][G][A][G][U] = 2.000;
+ int22_ar[G][C][U][U][G][C][G][U] = 0.500;
+ int22_ar[G][C][U][U][G][G][G][U] = -2.500;
+ int22_ar[G][C][U][U][G][U][G][U] = 1.500;
+ int22_ar[G][C][U][U][U][A][G][U] = 2.000;
+ int22_ar[G][C][U][U][U][C][G][U] = -0.200;
+ int22_ar[G][C][U][U][U][G][G][U] = -0.300;
+ int22_ar[G][C][U][U][U][U][G][U] = 0.000;
+ int22_ar[G][C][A][A][A][A][U][A] = 2.100;
+ int22_ar[G][C][A][A][A][C][U][A] = 1.800;
+ int22_ar[G][C][A][A][A][G][U][A] = 0.700;
+ int22_ar[G][C][A][A][A][U][U][A] = 2.000;
+ int22_ar[G][C][A][A][C][A][U][A] = 1.700;
+ int22_ar[G][C][A][A][C][C][U][A] = 1.400;
+ int22_ar[G][C][A][A][C][G][U][A] = 0.300;
+ int22_ar[G][C][A][A][C][U][U][A] = 2.000;
+ int22_ar[G][C][A][A][G][A][U][A] = 1.100;
+ int22_ar[G][C][A][A][G][C][U][A] = 0.800;
+ int22_ar[G][C][A][A][G][G][U][A] = -0.300;
+ int22_ar[G][C][A][A][G][U][U][A] = 2.000;
+ int22_ar[G][C][A][A][U][A][U][A] = 2.000;
+ int22_ar[G][C][A][A][U][C][U][A] = 2.000;
+ int22_ar[G][C][A][A][U][G][U][A] = 2.000;
+ int22_ar[G][C][A][A][U][U][U][A] = 2.000;
+ int22_ar[G][C][A][C][A][A][U][A] = 2.100;
+ int22_ar[G][C][A][C][A][C][U][A] = 1.800;
+ int22_ar[G][C][A][C][A][G][U][A] = 0.700;
+ int22_ar[G][C][A][C][A][U][U][A] = 2.000;
+ int22_ar[G][C][A][C][C][A][U][A] = 2.700;
+ int22_ar[G][C][A][C][C][C][U][A] = 1.800;
+ int22_ar[G][C][A][C][C][G][U][A] = 1.700;
+ int22_ar[G][C][A][C][C][U][U][A] = 2.000;
+ int22_ar[G][C][A][C][G][A][U][A] = 2.000;
+ int22_ar[G][C][A][C][G][C][U][A] = 2.000;
+ int22_ar[G][C][A][C][G][G][U][A] = 2.000;
+ int22_ar[G][C][A][C][G][U][U][A] = 2.000;
+ int22_ar[G][C][A][C][U][A][U][A] = 2.700;
+ int22_ar[G][C][A][C][U][C][U][A] = 1.800;
+ int22_ar[G][C][A][C][U][G][U][A] = 1.700;
+ int22_ar[G][C][A][C][U][U][U][A] = 2.000;
+ int22_ar[G][C][A][G][A][A][U][A] = 1.100;
+ int22_ar[G][C][A][G][A][C][U][A] = 0.800;
+ int22_ar[G][C][A][G][A][G][U][A] = -0.300;
+ int22_ar[G][C][A][G][A][U][U][A] = 2.000;
+ int22_ar[G][C][A][G][C][A][U][A] = 2.000;
+ int22_ar[G][C][A][G][C][C][U][A] = 2.000;
+ int22_ar[G][C][A][G][C][G][U][A] = 2.000;
+ int22_ar[G][C][A][G][C][U][U][A] = 2.000;
+ int22_ar[G][C][A][G][G][A][U][A] = 1.500;
+ int22_ar[G][C][A][G][G][C][U][A] = 1.200;
+ int22_ar[G][C][A][G][G][G][U][A] = 0.100;
+ int22_ar[G][C][A][G][G][U][U][A] = 2.000;
+ int22_ar[G][C][A][G][U][A][U][A] = 0.300;
+ int22_ar[G][C][A][G][U][C][U][A] = -1.000;
+ int22_ar[G][C][A][G][U][G][U][A] = -0.300;
+ int22_ar[G][C][A][G][U][U][U][A] = 2.000;
+ int22_ar[G][C][A][U][A][A][U][A] = 2.000;
+ int22_ar[G][C][A][U][A][C][U][A] = 2.000;
+ int22_ar[G][C][A][U][A][G][U][A] = 2.000;
+ int22_ar[G][C][A][U][A][U][U][A] = 2.000;
+ int22_ar[G][C][A][U][C][A][U][A] = 2.400;
+ int22_ar[G][C][A][U][C][C][U][A] = 1.500;
+ int22_ar[G][C][A][U][C][G][U][A] = 1.400;
+ int22_ar[G][C][A][U][C][U][U][A] = 2.000;
+ int22_ar[G][C][A][U][G][A][U][A] = 1.600;
+ int22_ar[G][C][A][U][G][C][U][A] = 0.300;
+ int22_ar[G][C][A][U][G][G][U][A] = 1.000;
+ int22_ar[G][C][A][U][G][U][U][A] = 2.000;
+ int22_ar[G][C][A][U][U][A][U][A] = 2.300;
+ int22_ar[G][C][A][U][U][C][U][A] = 1.000;
+ int22_ar[G][C][A][U][U][G][U][A] = 1.700;
+ int22_ar[G][C][A][U][U][U][U][A] = 2.000;
+ int22_ar[G][C][C][A][A][A][U][A] = 1.900;
+ int22_ar[G][C][C][A][A][C][U][A] = 2.500;
+ int22_ar[G][C][C][A][A][G][U][A] = 2.000;
+ int22_ar[G][C][C][A][A][U][U][A] = 2.500;
+ int22_ar[G][C][C][A][C][A][U][A] = 1.400;
+ int22_ar[G][C][C][A][C][C][U][A] = 1.400;
+ int22_ar[G][C][C][A][C][G][U][A] = 2.000;
+ int22_ar[G][C][C][A][C][U][U][A] = 1.500;
+ int22_ar[G][C][C][A][G][A][U][A] = 0.800;
+ int22_ar[G][C][C][A][G][C][U][A] = 1.800;
+ int22_ar[G][C][C][A][G][G][U][A] = 2.000;
+ int22_ar[G][C][C][A][G][U][U][A] = 1.900;
+ int22_ar[G][C][C][A][U][A][U][A] = 2.000;
+ int22_ar[G][C][C][A][U][C][U][A] = 2.000;
+ int22_ar[G][C][C][A][U][G][U][A] = 2.000;
+ int22_ar[G][C][C][A][U][U][U][A] = 2.000;
+ int22_ar[G][C][C][C][A][A][U][A] = 1.900;
+ int22_ar[G][C][C][C][A][C][U][A] = 1.900;
+ int22_ar[G][C][C][C][A][G][U][A] = 2.000;
+ int22_ar[G][C][C][C][A][U][U][A] = 1.900;
+ int22_ar[G][C][C][C][C][A][U][A] = 1.900;
+ int22_ar[G][C][C][C][C][C][U][A] = 1.900;
+ int22_ar[G][C][C][C][C][G][U][A] = 2.000;
+ int22_ar[G][C][C][C][C][U][U][A] = 1.900;
+ int22_ar[G][C][C][C][G][A][U][A] = 2.000;
+ int22_ar[G][C][C][C][G][C][U][A] = 2.000;
+ int22_ar[G][C][C][C][G][G][U][A] = 2.000;
+ int22_ar[G][C][C][C][G][U][U][A] = 2.000;
+ int22_ar[G][C][C][C][U][A][U][A] = 1.900;
+ int22_ar[G][C][C][C][U][C][U][A] = 1.900;
+ int22_ar[G][C][C][C][U][G][U][A] = 2.000;
+ int22_ar[G][C][C][C][U][U][U][A] = 1.900;
+ int22_ar[G][C][C][G][A][A][U][A] = 0.800;
+ int22_ar[G][C][C][G][A][C][U][A] = 1.800;
+ int22_ar[G][C][C][G][A][G][U][A] = 2.000;
+ int22_ar[G][C][C][G][A][U][U][A] = 1.900;
+ int22_ar[G][C][C][G][C][A][U][A] = 2.000;
+ int22_ar[G][C][C][G][C][C][U][A] = 2.000;
+ int22_ar[G][C][C][G][C][G][U][A] = 2.000;
+ int22_ar[G][C][C][G][C][U][U][A] = 2.000;
+ int22_ar[G][C][C][G][G][A][U][A] = 1.200;
+ int22_ar[G][C][C][G][G][C][U][A] = 1.800;
+ int22_ar[G][C][C][G][G][G][U][A] = 2.000;
+ int22_ar[G][C][C][G][G][U][U][A] = 1.900;
+ int22_ar[G][C][C][G][U][A][U][A] = -0.900;
+ int22_ar[G][C][C][G][U][C][U][A] = 0.100;
+ int22_ar[G][C][C][G][U][G][U][A] = 2.000;
+ int22_ar[G][C][C][G][U][U][U][A] = 0.100;
+ int22_ar[G][C][C][U][A][A][U][A] = 2.000;
+ int22_ar[G][C][C][U][A][C][U][A] = 2.000;
+ int22_ar[G][C][C][U][A][G][U][A] = 2.000;
+ int22_ar[G][C][C][U][A][U][U][A] = 2.000;
+ int22_ar[G][C][C][U][C][A][U][A] = 1.600;
+ int22_ar[G][C][C][U][C][C][U][A] = 1.600;
+ int22_ar[G][C][C][U][C][G][U][A] = 2.000;
+ int22_ar[G][C][C][U][C][U][U][A] = 1.600;
+ int22_ar[G][C][C][U][G][A][U][A] = 0.300;
+ int22_ar[G][C][C][U][G][C][U][A] = 1.300;
+ int22_ar[G][C][C][U][G][G][U][A] = 2.000;
+ int22_ar[G][C][C][U][G][U][U][A] = 1.400;
+ int22_ar[G][C][C][U][U][A][U][A] = 1.000;
+ int22_ar[G][C][C][U][U][C][U][A] = 1.000;
+ int22_ar[G][C][C][U][U][G][U][A] = 2.000;
+ int22_ar[G][C][C][U][U][U][U][A] = 1.100;
+ int22_ar[G][C][G][A][A][A][U][A] = 0.100;
+ int22_ar[G][C][G][A][A][C][U][A] = 2.000;
+ int22_ar[G][C][G][A][A][G][U][A] = 1.800;
+ int22_ar[G][C][G][A][A][U][U][A] = 0.400;
+ int22_ar[G][C][G][A][C][A][U][A] = -0.300;
+ int22_ar[G][C][G][A][C][C][U][A] = 2.000;
+ int22_ar[G][C][G][A][C][G][U][A] = 1.300;
+ int22_ar[G][C][G][A][C][U][U][A] = -1.100;
+ int22_ar[G][C][G][A][G][A][U][A] = -0.900;
+ int22_ar[G][C][G][A][G][C][U][A] = 2.000;
+ int22_ar[G][C][G][A][G][G][U][A] = 0.700;
+ int22_ar[G][C][G][A][G][U][U][A] = 0.100;
+ int22_ar[G][C][G][A][U][A][U][A] = 2.000;
+ int22_ar[G][C][G][A][U][C][U][A] = 2.000;
+ int22_ar[G][C][G][A][U][G][U][A] = 2.000;
+ int22_ar[G][C][G][A][U][U][U][A] = 2.000;
+ int22_ar[G][C][G][C][A][A][U][A] = 0.100;
+ int22_ar[G][C][G][C][A][C][U][A] = 2.000;
+ int22_ar[G][C][G][C][A][G][U][A] = 1.800;
+ int22_ar[G][C][G][C][A][U][U][A] = -0.600;
+ int22_ar[G][C][G][C][C][A][U][A] = 1.100;
+ int22_ar[G][C][G][C][C][C][U][A] = 2.000;
+ int22_ar[G][C][G][C][C][G][U][A] = 2.400;
+ int22_ar[G][C][G][C][C][U][U][A] = 0.400;
+ int22_ar[G][C][G][C][G][A][U][A] = 2.000;
+ int22_ar[G][C][G][C][G][C][U][A] = 2.000;
+ int22_ar[G][C][G][C][G][G][U][A] = 2.000;
+ int22_ar[G][C][G][C][G][U][U][A] = 2.000;
+ int22_ar[G][C][G][C][U][A][U][A] = 1.100;
+ int22_ar[G][C][G][C][U][C][U][A] = 2.000;
+ int22_ar[G][C][G][C][U][G][U][A] = 2.400;
+ int22_ar[G][C][G][C][U][U][U][A] = 0.400;
+ int22_ar[G][C][G][G][A][A][U][A] = -0.900;
+ int22_ar[G][C][G][G][A][C][U][A] = 2.000;
+ int22_ar[G][C][G][G][A][G][U][A] = 0.700;
+ int22_ar[G][C][G][G][A][U][U][A] = 0.100;
+ int22_ar[G][C][G][G][C][A][U][A] = 2.000;
+ int22_ar[G][C][G][G][C][C][U][A] = 2.000;
+ int22_ar[G][C][G][G][C][G][U][A] = 2.000;
+ int22_ar[G][C][G][G][C][U][U][A] = 2.000;
+ int22_ar[G][C][G][G][G][A][U][A] = -0.500;
+ int22_ar[G][C][G][G][G][C][U][A] = 2.000;
+ int22_ar[G][C][G][G][G][G][U][A] = 1.100;
+ int22_ar[G][C][G][G][G][U][U][A] = -0.300;
+ int22_ar[G][C][G][G][U][A][U][A] = -0.900;
+ int22_ar[G][C][G][G][U][C][U][A] = 2.000;
+ int22_ar[G][C][G][G][U][G][U][A] = 0.000;
+ int22_ar[G][C][G][G][U][U][U][A] = -3.500;
+ int22_ar[G][C][G][U][A][A][U][A] = 2.000;
+ int22_ar[G][C][G][U][A][C][U][A] = 2.000;
+ int22_ar[G][C][G][U][A][G][U][A] = 2.000;
+ int22_ar[G][C][G][U][A][U][U][A] = 2.000;
+ int22_ar[G][C][G][U][C][A][U][A] = 0.800;
+ int22_ar[G][C][G][U][C][C][U][A] = 2.000;
+ int22_ar[G][C][G][U][C][G][U][A] = 2.100;
+ int22_ar[G][C][G][U][C][U][U][A] = 0.100;
+ int22_ar[G][C][G][U][G][A][U][A] = 0.400;
+ int22_ar[G][C][G][U][G][C][U][A] = 2.000;
+ int22_ar[G][C][G][U][G][G][U][A] = 1.200;
+ int22_ar[G][C][G][U][G][U][U][A] = -2.200;
+ int22_ar[G][C][G][U][U][A][U][A] = 1.100;
+ int22_ar[G][C][G][U][U][C][U][A] = 2.000;
+ int22_ar[G][C][G][U][U][G][U][A] = 1.900;
+ int22_ar[G][C][G][U][U][U][U][A] = 0.300;
+ int22_ar[G][C][U][A][A][A][U][A] = 2.000;
+ int22_ar[G][C][U][A][A][C][U][A] = 1.500;
+ int22_ar[G][C][U][A][A][G][U][A] = 0.000;
+ int22_ar[G][C][U][A][A][U][U][A] = 2.100;
+ int22_ar[G][C][U][A][C][A][U][A] = 2.000;
+ int22_ar[G][C][U][A][C][C][U][A] = 0.400;
+ int22_ar[G][C][U][A][C][G][U][A] = -1.500;
+ int22_ar[G][C][U][A][C][U][U][A] = 0.700;
+ int22_ar[G][C][U][A][G][A][U][A] = 2.000;
+ int22_ar[G][C][U][A][G][C][U][A] = 0.900;
+ int22_ar[G][C][U][A][G][G][U][A] = -0.300;
+ int22_ar[G][C][U][A][G][U][U][A] = 1.900;
+ int22_ar[G][C][U][A][U][A][U][A] = 2.000;
+ int22_ar[G][C][U][A][U][C][U][A] = 2.000;
+ int22_ar[G][C][U][A][U][G][U][A] = 2.000;
+ int22_ar[G][C][U][A][U][U][U][A] = 2.000;
+ int22_ar[G][C][U][C][A][A][U][A] = 2.000;
+ int22_ar[G][C][U][C][A][C][U][A] = 0.900;
+ int22_ar[G][C][U][C][A][G][U][A] = -1.000;
+ int22_ar[G][C][U][C][A][U][U][A] = 1.100;
+ int22_ar[G][C][U][C][C][A][U][A] = 2.000;
+ int22_ar[G][C][U][C][C][C][U][A] = 0.900;
+ int22_ar[G][C][U][C][C][G][U][A] = 0.000;
+ int22_ar[G][C][U][C][C][U][U][A] = 1.100;
+ int22_ar[G][C][U][C][G][A][U][A] = 2.000;
+ int22_ar[G][C][U][C][G][C][U][A] = 2.000;
+ int22_ar[G][C][U][C][G][G][U][A] = 2.000;
+ int22_ar[G][C][U][C][G][U][U][A] = 2.000;
+ int22_ar[G][C][U][C][U][A][U][A] = 2.000;
+ int22_ar[G][C][U][C][U][C][U][A] = 0.900;
+ int22_ar[G][C][U][C][U][G][U][A] = 0.000;
+ int22_ar[G][C][U][C][U][U][U][A] = 1.100;
+ int22_ar[G][C][U][G][A][A][U][A] = 2.000;
+ int22_ar[G][C][U][G][A][C][U][A] = 0.900;
+ int22_ar[G][C][U][G][A][G][U][A] = -0.300;
+ int22_ar[G][C][U][G][A][U][U][A] = 1.900;
+ int22_ar[G][C][U][G][C][A][U][A] = 2.000;
+ int22_ar[G][C][U][G][C][C][U][A] = 2.000;
+ int22_ar[G][C][U][G][C][G][U][A] = 2.000;
+ int22_ar[G][C][U][G][C][U][U][A] = 2.000;
+ int22_ar[G][C][U][G][G][A][U][A] = 2.000;
+ int22_ar[G][C][U][G][G][C][U][A] = 0.800;
+ int22_ar[G][C][U][G][G][G][U][A] = -0.700;
+ int22_ar[G][C][U][G][G][U][U][A] = 1.500;
+ int22_ar[G][C][U][G][U][A][U][A] = 2.000;
+ int22_ar[G][C][U][G][U][C][U][A] = -0.900;
+ int22_ar[G][C][U][G][U][G][U][A] = -3.900;
+ int22_ar[G][C][U][G][U][U][U][A] = 0.100;
+ int22_ar[G][C][U][U][A][A][U][A] = 2.000;
+ int22_ar[G][C][U][U][A][C][U][A] = 2.000;
+ int22_ar[G][C][U][U][A][G][U][A] = 2.000;
+ int22_ar[G][C][U][U][A][U][U][A] = 2.000;
+ int22_ar[G][C][U][U][C][A][U][A] = 2.000;
+ int22_ar[G][C][U][U][C][C][U][A] = 0.600;
+ int22_ar[G][C][U][U][C][G][U][A] = -0.300;
+ int22_ar[G][C][U][U][C][U][U][A] = 0.800;
+ int22_ar[G][C][U][U][G][A][U][A] = 2.000;
+ int22_ar[G][C][U][U][G][C][U][A] = 0.400;
+ int22_ar[G][C][U][U][G][G][U][A] = -2.600;
+ int22_ar[G][C][U][U][G][U][U][A] = 1.400;
+ int22_ar[G][C][U][U][U][A][U][A] = 2.000;
+ int22_ar[G][C][U][U][U][C][U][A] = 0.000;
+ int22_ar[G][C][U][U][U][G][U][A] = -0.100;
+ int22_ar[G][C][U][U][U][U][U][A] = 0.300;
+ int22_ar[G][C][A][A][A][A][U][G] = 2.100;
+ int22_ar[G][C][A][A][A][C][U][G] = 1.800;
+ int22_ar[G][C][A][A][A][G][U][G] = 0.700;
+ int22_ar[G][C][A][A][A][U][U][G] = 2.000;
+ int22_ar[G][C][A][A][C][A][U][G] = 1.700;
+ int22_ar[G][C][A][A][C][C][U][G] = 1.400;
+ int22_ar[G][C][A][A][C][G][U][G] = 0.300;
+ int22_ar[G][C][A][A][C][U][U][G] = 2.000;
+ int22_ar[G][C][A][A][G][A][U][G] = 1.100;
+ int22_ar[G][C][A][A][G][C][U][G] = 0.800;
+ int22_ar[G][C][A][A][G][G][U][G] = -0.300;
+ int22_ar[G][C][A][A][G][U][U][G] = 2.000;
+ int22_ar[G][C][A][A][U][A][U][G] = 2.000;
+ int22_ar[G][C][A][A][U][C][U][G] = 2.000;
+ int22_ar[G][C][A][A][U][G][U][G] = 2.000;
+ int22_ar[G][C][A][A][U][U][U][G] = 2.000;
+ int22_ar[G][C][A][C][A][A][U][G] = 2.100;
+ int22_ar[G][C][A][C][A][C][U][G] = 1.800;
+ int22_ar[G][C][A][C][A][G][U][G] = 0.700;
+ int22_ar[G][C][A][C][A][U][U][G] = 2.000;
+ int22_ar[G][C][A][C][C][A][U][G] = 2.700;
+ int22_ar[G][C][A][C][C][C][U][G] = 1.800;
+ int22_ar[G][C][A][C][C][G][U][G] = 1.700;
+ int22_ar[G][C][A][C][C][U][U][G] = 2.000;
+ int22_ar[G][C][A][C][G][A][U][G] = 2.000;
+ int22_ar[G][C][A][C][G][C][U][G] = 2.000;
+ int22_ar[G][C][A][C][G][G][U][G] = 2.000;
+ int22_ar[G][C][A][C][G][U][U][G] = 2.000;
+ int22_ar[G][C][A][C][U][A][U][G] = 2.700;
+ int22_ar[G][C][A][C][U][C][U][G] = 1.800;
+ int22_ar[G][C][A][C][U][G][U][G] = 1.700;
+ int22_ar[G][C][A][C][U][U][U][G] = 2.000;
+ int22_ar[G][C][A][G][A][A][U][G] = 1.100;
+ int22_ar[G][C][A][G][A][C][U][G] = 0.800;
+ int22_ar[G][C][A][G][A][G][U][G] = -0.300;
+ int22_ar[G][C][A][G][A][U][U][G] = 2.000;
+ int22_ar[G][C][A][G][C][A][U][G] = 2.000;
+ int22_ar[G][C][A][G][C][C][U][G] = 2.000;
+ int22_ar[G][C][A][G][C][G][U][G] = 2.000;
+ int22_ar[G][C][A][G][C][U][U][G] = 2.000;
+ int22_ar[G][C][A][G][G][A][U][G] = 1.500;
+ int22_ar[G][C][A][G][G][C][U][G] = 1.200;
+ int22_ar[G][C][A][G][G][G][U][G] = 0.100;
+ int22_ar[G][C][A][G][G][U][U][G] = 2.000;
+ int22_ar[G][C][A][G][U][A][U][G] = 0.300;
+ int22_ar[G][C][A][G][U][C][U][G] = -1.000;
+ int22_ar[G][C][A][G][U][G][U][G] = -0.300;
+ int22_ar[G][C][A][G][U][U][U][G] = 2.000;
+ int22_ar[G][C][A][U][A][A][U][G] = 2.000;
+ int22_ar[G][C][A][U][A][C][U][G] = 2.000;
+ int22_ar[G][C][A][U][A][G][U][G] = 2.000;
+ int22_ar[G][C][A][U][A][U][U][G] = 2.000;
+ int22_ar[G][C][A][U][C][A][U][G] = 2.400;
+ int22_ar[G][C][A][U][C][C][U][G] = 1.500;
+ int22_ar[G][C][A][U][C][G][U][G] = 1.400;
+ int22_ar[G][C][A][U][C][U][U][G] = 2.000;
+ int22_ar[G][C][A][U][G][A][U][G] = 1.600;
+ int22_ar[G][C][A][U][G][C][U][G] = 0.300;
+ int22_ar[G][C][A][U][G][G][U][G] = 1.000;
+ int22_ar[G][C][A][U][G][U][U][G] = 2.000;
+ int22_ar[G][C][A][U][U][A][U][G] = 2.300;
+ int22_ar[G][C][A][U][U][C][U][G] = 1.000;
+ int22_ar[G][C][A][U][U][G][U][G] = 1.700;
+ int22_ar[G][C][A][U][U][U][U][G] = 2.000;
+ int22_ar[G][C][C][A][A][A][U][G] = 1.900;
+ int22_ar[G][C][C][A][A][C][U][G] = 2.500;
+ int22_ar[G][C][C][A][A][G][U][G] = 2.000;
+ int22_ar[G][C][C][A][A][U][U][G] = 2.500;
+ int22_ar[G][C][C][A][C][A][U][G] = 1.400;
+ int22_ar[G][C][C][A][C][C][U][G] = 1.400;
+ int22_ar[G][C][C][A][C][G][U][G] = 2.000;
+ int22_ar[G][C][C][A][C][U][U][G] = 1.500;
+ int22_ar[G][C][C][A][G][A][U][G] = 0.800;
+ int22_ar[G][C][C][A][G][C][U][G] = 1.800;
+ int22_ar[G][C][C][A][G][G][U][G] = 2.000;
+ int22_ar[G][C][C][A][G][U][U][G] = 1.900;
+ int22_ar[G][C][C][A][U][A][U][G] = 2.000;
+ int22_ar[G][C][C][A][U][C][U][G] = 2.000;
+ int22_ar[G][C][C][A][U][G][U][G] = 2.000;
+ int22_ar[G][C][C][A][U][U][U][G] = 2.000;
+ int22_ar[G][C][C][C][A][A][U][G] = 1.900;
+ int22_ar[G][C][C][C][A][C][U][G] = 1.900;
+ int22_ar[G][C][C][C][A][G][U][G] = 2.000;
+ int22_ar[G][C][C][C][A][U][U][G] = 1.900;
+ int22_ar[G][C][C][C][C][A][U][G] = 1.900;
+ int22_ar[G][C][C][C][C][C][U][G] = 1.900;
+ int22_ar[G][C][C][C][C][G][U][G] = 2.000;
+ int22_ar[G][C][C][C][C][U][U][G] = 1.900;
+ int22_ar[G][C][C][C][G][A][U][G] = 2.000;
+ int22_ar[G][C][C][C][G][C][U][G] = 2.000;
+ int22_ar[G][C][C][C][G][G][U][G] = 2.000;
+ int22_ar[G][C][C][C][G][U][U][G] = 2.000;
+ int22_ar[G][C][C][C][U][A][U][G] = 1.900;
+ int22_ar[G][C][C][C][U][C][U][G] = 1.900;
+ int22_ar[G][C][C][C][U][G][U][G] = 2.000;
+ int22_ar[G][C][C][C][U][U][U][G] = 1.900;
+ int22_ar[G][C][C][G][A][A][U][G] = 0.800;
+ int22_ar[G][C][C][G][A][C][U][G] = 1.800;
+ int22_ar[G][C][C][G][A][G][U][G] = 2.000;
+ int22_ar[G][C][C][G][A][U][U][G] = 1.900;
+ int22_ar[G][C][C][G][C][A][U][G] = 2.000;
+ int22_ar[G][C][C][G][C][C][U][G] = 2.000;
+ int22_ar[G][C][C][G][C][G][U][G] = 2.000;
+ int22_ar[G][C][C][G][C][U][U][G] = 2.000;
+ int22_ar[G][C][C][G][G][A][U][G] = 1.200;
+ int22_ar[G][C][C][G][G][C][U][G] = 1.800;
+ int22_ar[G][C][C][G][G][G][U][G] = 2.000;
+ int22_ar[G][C][C][G][G][U][U][G] = 1.900;
+ int22_ar[G][C][C][G][U][A][U][G] = -0.900;
+ int22_ar[G][C][C][G][U][C][U][G] = 0.100;
+ int22_ar[G][C][C][G][U][G][U][G] = 2.000;
+ int22_ar[G][C][C][G][U][U][U][G] = 0.100;
+ int22_ar[G][C][C][U][A][A][U][G] = 2.000;
+ int22_ar[G][C][C][U][A][C][U][G] = 2.000;
+ int22_ar[G][C][C][U][A][G][U][G] = 2.000;
+ int22_ar[G][C][C][U][A][U][U][G] = 2.000;
+ int22_ar[G][C][C][U][C][A][U][G] = 1.600;
+ int22_ar[G][C][C][U][C][C][U][G] = 1.600;
+ int22_ar[G][C][C][U][C][G][U][G] = 2.000;
+ int22_ar[G][C][C][U][C][U][U][G] = 1.600;
+ int22_ar[G][C][C][U][G][A][U][G] = 0.300;
+ int22_ar[G][C][C][U][G][C][U][G] = 1.300;
+ int22_ar[G][C][C][U][G][G][U][G] = 2.000;
+ int22_ar[G][C][C][U][G][U][U][G] = 1.400;
+ int22_ar[G][C][C][U][U][A][U][G] = 1.000;
+ int22_ar[G][C][C][U][U][C][U][G] = 1.000;
+ int22_ar[G][C][C][U][U][G][U][G] = 2.000;
+ int22_ar[G][C][C][U][U][U][U][G] = 1.100;
+ int22_ar[G][C][G][A][A][A][U][G] = 0.100;
+ int22_ar[G][C][G][A][A][C][U][G] = 2.000;
+ int22_ar[G][C][G][A][A][G][U][G] = 1.800;
+ int22_ar[G][C][G][A][A][U][U][G] = 0.400;
+ int22_ar[G][C][G][A][C][A][U][G] = -0.300;
+ int22_ar[G][C][G][A][C][C][U][G] = 2.000;
+ int22_ar[G][C][G][A][C][G][U][G] = 1.300;
+ int22_ar[G][C][G][A][C][U][U][G] = -1.100;
+ int22_ar[G][C][G][A][G][A][U][G] = -0.900;
+ int22_ar[G][C][G][A][G][C][U][G] = 2.000;
+ int22_ar[G][C][G][A][G][G][U][G] = 0.700;
+ int22_ar[G][C][G][A][G][U][U][G] = 0.100;
+ int22_ar[G][C][G][A][U][A][U][G] = 2.000;
+ int22_ar[G][C][G][A][U][C][U][G] = 2.000;
+ int22_ar[G][C][G][A][U][G][U][G] = 2.000;
+ int22_ar[G][C][G][A][U][U][U][G] = 2.000;
+ int22_ar[G][C][G][C][A][A][U][G] = 0.100;
+ int22_ar[G][C][G][C][A][C][U][G] = 2.000;
+ int22_ar[G][C][G][C][A][G][U][G] = 1.800;
+ int22_ar[G][C][G][C][A][U][U][G] = -0.600;
+ int22_ar[G][C][G][C][C][A][U][G] = 1.100;
+ int22_ar[G][C][G][C][C][C][U][G] = 2.000;
+ int22_ar[G][C][G][C][C][G][U][G] = 2.400;
+ int22_ar[G][C][G][C][C][U][U][G] = 0.400;
+ int22_ar[G][C][G][C][G][A][U][G] = 2.000;
+ int22_ar[G][C][G][C][G][C][U][G] = 2.000;
+ int22_ar[G][C][G][C][G][G][U][G] = 2.000;
+ int22_ar[G][C][G][C][G][U][U][G] = 2.000;
+ int22_ar[G][C][G][C][U][A][U][G] = 1.100;
+ int22_ar[G][C][G][C][U][C][U][G] = 2.000;
+ int22_ar[G][C][G][C][U][G][U][G] = 2.400;
+ int22_ar[G][C][G][C][U][U][U][G] = 0.400;
+ int22_ar[G][C][G][G][A][A][U][G] = -0.900;
+ int22_ar[G][C][G][G][A][C][U][G] = 2.000;
+ int22_ar[G][C][G][G][A][G][U][G] = 0.700;
+ int22_ar[G][C][G][G][A][U][U][G] = 0.100;
+ int22_ar[G][C][G][G][C][A][U][G] = 2.000;
+ int22_ar[G][C][G][G][C][C][U][G] = 2.000;
+ int22_ar[G][C][G][G][C][G][U][G] = 2.000;
+ int22_ar[G][C][G][G][C][U][U][G] = 2.000;
+ int22_ar[G][C][G][G][G][A][U][G] = -0.500;
+ int22_ar[G][C][G][G][G][C][U][G] = 2.000;
+ int22_ar[G][C][G][G][G][G][U][G] = 1.100;
+ int22_ar[G][C][G][G][G][U][U][G] = -0.300;
+ int22_ar[G][C][G][G][U][A][U][G] = -0.900;
+ int22_ar[G][C][G][G][U][C][U][G] = 2.000;
+ int22_ar[G][C][G][G][U][G][U][G] = 0.000;
+ int22_ar[G][C][G][G][U][U][U][G] = -3.500;
+ int22_ar[G][C][G][U][A][A][U][G] = 2.000;
+ int22_ar[G][C][G][U][A][C][U][G] = 2.000;
+ int22_ar[G][C][G][U][A][G][U][G] = 2.000;
+ int22_ar[G][C][G][U][A][U][U][G] = 2.000;
+ int22_ar[G][C][G][U][C][A][U][G] = 0.800;
+ int22_ar[G][C][G][U][C][C][U][G] = 2.000;
+ int22_ar[G][C][G][U][C][G][U][G] = 2.100;
+ int22_ar[G][C][G][U][C][U][U][G] = 0.100;
+ int22_ar[G][C][G][U][G][A][U][G] = 0.400;
+ int22_ar[G][C][G][U][G][C][U][G] = 2.000;
+ int22_ar[G][C][G][U][G][G][U][G] = 1.200;
+ int22_ar[G][C][G][U][G][U][U][G] = -2.200;
+ int22_ar[G][C][G][U][U][A][U][G] = 1.100;
+ int22_ar[G][C][G][U][U][C][U][G] = 2.000;
+ int22_ar[G][C][G][U][U][G][U][G] = 1.900;
+ int22_ar[G][C][G][U][U][U][U][G] = 0.300;
+ int22_ar[G][C][U][A][A][A][U][G] = 2.000;
+ int22_ar[G][C][U][A][A][C][U][G] = 1.500;
+ int22_ar[G][C][U][A][A][G][U][G] = 0.000;
+ int22_ar[G][C][U][A][A][U][U][G] = 2.100;
+ int22_ar[G][C][U][A][C][A][U][G] = 2.000;
+ int22_ar[G][C][U][A][C][C][U][G] = 0.400;
+ int22_ar[G][C][U][A][C][G][U][G] = -1.500;
+ int22_ar[G][C][U][A][C][U][U][G] = 0.700;
+ int22_ar[G][C][U][A][G][A][U][G] = 2.000;
+ int22_ar[G][C][U][A][G][C][U][G] = 0.900;
+ int22_ar[G][C][U][A][G][G][U][G] = -0.300;
+ int22_ar[G][C][U][A][G][U][U][G] = 1.900;
+ int22_ar[G][C][U][A][U][A][U][G] = 2.000;
+ int22_ar[G][C][U][A][U][C][U][G] = 2.000;
+ int22_ar[G][C][U][A][U][G][U][G] = 2.000;
+ int22_ar[G][C][U][A][U][U][U][G] = 2.000;
+ int22_ar[G][C][U][C][A][A][U][G] = 2.000;
+ int22_ar[G][C][U][C][A][C][U][G] = 0.900;
+ int22_ar[G][C][U][C][A][G][U][G] = -1.000;
+ int22_ar[G][C][U][C][A][U][U][G] = 1.100;
+ int22_ar[G][C][U][C][C][A][U][G] = 2.000;
+ int22_ar[G][C][U][C][C][C][U][G] = 0.900;
+ int22_ar[G][C][U][C][C][G][U][G] = 0.000;
+ int22_ar[G][C][U][C][C][U][U][G] = 1.100;
+ int22_ar[G][C][U][C][G][A][U][G] = 2.000;
+ int22_ar[G][C][U][C][G][C][U][G] = 2.000;
+ int22_ar[G][C][U][C][G][G][U][G] = 2.000;
+ int22_ar[G][C][U][C][G][U][U][G] = 2.000;
+ int22_ar[G][C][U][C][U][A][U][G] = 2.000;
+ int22_ar[G][C][U][C][U][C][U][G] = 0.900;
+ int22_ar[G][C][U][C][U][G][U][G] = 0.000;
+ int22_ar[G][C][U][C][U][U][U][G] = 1.100;
+ int22_ar[G][C][U][G][A][A][U][G] = 2.000;
+ int22_ar[G][C][U][G][A][C][U][G] = 0.900;
+ int22_ar[G][C][U][G][A][G][U][G] = -0.300;
+ int22_ar[G][C][U][G][A][U][U][G] = 1.900;
+ int22_ar[G][C][U][G][C][A][U][G] = 2.000;
+ int22_ar[G][C][U][G][C][C][U][G] = 2.000;
+ int22_ar[G][C][U][G][C][G][U][G] = 2.000;
+ int22_ar[G][C][U][G][C][U][U][G] = 2.000;
+ int22_ar[G][C][U][G][G][A][U][G] = 2.000;
+ int22_ar[G][C][U][G][G][C][U][G] = 0.800;
+ int22_ar[G][C][U][G][G][G][U][G] = -0.700;
+ int22_ar[G][C][U][G][G][U][U][G] = 1.500;
+ int22_ar[G][C][U][G][U][A][U][G] = 2.000;
+ int22_ar[G][C][U][G][U][C][U][G] = -0.900;
+ int22_ar[G][C][U][G][U][G][U][G] = -3.900;
+ int22_ar[G][C][U][G][U][U][U][G] = 0.100;
+ int22_ar[G][C][U][U][A][A][U][G] = 2.000;
+ int22_ar[G][C][U][U][A][C][U][G] = 2.000;
+ int22_ar[G][C][U][U][A][G][U][G] = 2.000;
+ int22_ar[G][C][U][U][A][U][U][G] = 2.000;
+ int22_ar[G][C][U][U][C][A][U][G] = 2.000;
+ int22_ar[G][C][U][U][C][C][U][G] = 0.600;
+ int22_ar[G][C][U][U][C][G][U][G] = -0.300;
+ int22_ar[G][C][U][U][C][U][U][G] = 0.800;
+ int22_ar[G][C][U][U][G][A][U][G] = 2.000;
+ int22_ar[G][C][U][U][G][C][U][G] = 0.400;
+ int22_ar[G][C][U][U][G][G][U][G] = -2.600;
+ int22_ar[G][C][U][U][G][U][U][G] = 1.400;
+ int22_ar[G][C][U][U][U][A][U][G] = 2.000;
+ int22_ar[G][C][U][U][U][C][U][G] = 0.000;
+ int22_ar[G][C][U][U][U][G][U][G] = -0.100;
+ int22_ar[G][C][U][U][U][U][U][G] = 0.300;
+ int22_ar[G][U][A][A][A][A][A][U] = 2.800;
+ int22_ar[G][U][A][A][A][C][A][U] = 2.600;
+ int22_ar[G][U][A][A][A][G][A][U] = 1.500;
+ int22_ar[G][U][A][A][A][U][A][U] = 2.000;
+ int22_ar[G][U][A][A][C][A][A][U] = 2.500;
+ int22_ar[G][U][A][A][C][C][A][U] = 2.400;
+ int22_ar[G][U][A][A][C][G][A][U] = 1.300;
+ int22_ar[G][U][A][A][C][U][A][U] = 2.000;
+ int22_ar[G][U][A][A][G][A][A][U] = 1.500;
+ int22_ar[G][U][A][A][G][C][A][U] = 1.400;
+ int22_ar[G][U][A][A][G][G][A][U] = 0.300;
+ int22_ar[G][U][A][A][G][U][A][U] = 2.000;
+ int22_ar[G][U][A][A][U][A][A][U] = 2.000;
+ int22_ar[G][U][A][A][U][C][A][U] = 2.000;
+ int22_ar[G][U][A][A][U][G][A][U] = 2.000;
+ int22_ar[G][U][A][A][U][U][A][U] = 2.000;
+ int22_ar[G][U][A][C][A][A][A][U] = 2.600;
+ int22_ar[G][U][A][C][A][C][A][U] = 2.500;
+ int22_ar[G][U][A][C][A][G][A][U] = 1.400;
+ int22_ar[G][U][A][C][A][U][A][U] = 2.000;
+ int22_ar[G][U][A][C][C][A][A][U] = 3.100;
+ int22_ar[G][U][A][C][C][C][A][U] = 2.300;
+ int22_ar[G][U][A][C][C][G][A][U] = 2.200;
+ int22_ar[G][U][A][C][C][U][A][U] = 2.000;
+ int22_ar[G][U][A][C][G][A][A][U] = 2.000;
+ int22_ar[G][U][A][C][G][C][A][U] = 2.000;
+ int22_ar[G][U][A][C][G][G][A][U] = 2.000;
+ int22_ar[G][U][A][C][G][U][A][U] = 2.000;
+ int22_ar[G][U][A][C][U][A][A][U] = 3.100;
+ int22_ar[G][U][A][C][U][C][A][U] = 2.300;
+ int22_ar[G][U][A][C][U][G][A][U] = 2.200;
+ int22_ar[G][U][A][C][U][U][A][U] = 2.000;
+ int22_ar[G][U][A][G][A][A][A][U] = 1.500;
+ int22_ar[G][U][A][G][A][C][A][U] = 1.400;
+ int22_ar[G][U][A][G][A][G][A][U] = 0.300;
+ int22_ar[G][U][A][G][A][U][A][U] = 2.000;
+ int22_ar[G][U][A][G][C][A][A][U] = 2.000;
+ int22_ar[G][U][A][G][C][C][A][U] = 2.000;
+ int22_ar[G][U][A][G][C][G][A][U] = 2.000;
+ int22_ar[G][U][A][G][C][U][A][U] = 2.000;
+ int22_ar[G][U][A][G][G][A][A][U] = 2.100;
+ int22_ar[G][U][A][G][G][C][A][U] = 1.900;
+ int22_ar[G][U][A][G][G][G][A][U] = 0.800;
+ int22_ar[G][U][A][G][G][U][A][U] = 2.000;
+ int22_ar[G][U][A][G][U][A][A][U] = 1.300;
+ int22_ar[G][U][A][G][U][C][A][U] = 0.200;
+ int22_ar[G][U][A][G][U][G][A][U] = 0.900;
+ int22_ar[G][U][A][G][U][U][A][U] = 2.000;
+ int22_ar[G][U][A][U][A][A][A][U] = 2.000;
+ int22_ar[G][U][A][U][A][C][A][U] = 2.000;
+ int22_ar[G][U][A][U][A][G][A][U] = 2.000;
+ int22_ar[G][U][A][U][A][U][A][U] = 2.000;
+ int22_ar[G][U][A][U][C][A][A][U] = 3.100;
+ int22_ar[G][U][A][U][C][C][A][U] = 2.300;
+ int22_ar[G][U][A][U][C][G][A][U] = 2.200;
+ int22_ar[G][U][A][U][C][U][A][U] = 2.000;
+ int22_ar[G][U][A][U][G][A][A][U] = 2.300;
+ int22_ar[G][U][A][U][G][C][A][U] = 1.200;
+ int22_ar[G][U][A][U][G][G][A][U] = 1.900;
+ int22_ar[G][U][A][U][G][U][A][U] = 2.000;
+ int22_ar[G][U][A][U][U][A][A][U] = 2.700;
+ int22_ar[G][U][A][U][U][C][A][U] = 1.500;
+ int22_ar[G][U][A][U][U][G][A][U] = 2.200;
+ int22_ar[G][U][A][U][U][U][A][U] = 2.000;
+ int22_ar[G][U][C][A][A][A][A][U] = 2.500;
+ int22_ar[G][U][C][A][A][C][A][U] = 3.100;
+ int22_ar[G][U][C][A][A][G][A][U] = 2.000;
+ int22_ar[G][U][C][A][A][U][A][U] = 3.100;
+ int22_ar[G][U][C][A][C][A][A][U] = 2.300;
+ int22_ar[G][U][C][A][C][C][A][U] = 2.200;
+ int22_ar[G][U][C][A][C][G][A][U] = 2.000;
+ int22_ar[G][U][C][A][C][U][A][U] = 2.200;
+ int22_ar[G][U][C][A][G][A][A][U] = 1.300;
+ int22_ar[G][U][C][A][G][C][A][U] = 2.200;
+ int22_ar[G][U][C][A][G][G][A][U] = 2.000;
+ int22_ar[G][U][C][A][G][U][A][U] = 2.200;
+ int22_ar[G][U][C][A][U][A][A][U] = 2.000;
+ int22_ar[G][U][C][A][U][C][A][U] = 2.000;
+ int22_ar[G][U][C][A][U][G][A][U] = 2.000;
+ int22_ar[G][U][C][A][U][U][A][U] = 2.000;
+ int22_ar[G][U][C][C][A][A][A][U] = 2.400;
+ int22_ar[G][U][C][C][A][C][A][U] = 2.300;
+ int22_ar[G][U][C][C][A][G][A][U] = 2.000;
+ int22_ar[G][U][C][C][A][U][A][U] = 2.300;
+ int22_ar[G][U][C][C][C][A][A][U] = 2.200;
+ int22_ar[G][U][C][C][C][C][A][U] = 2.200;
+ int22_ar[G][U][C][C][C][G][A][U] = 2.000;
+ int22_ar[G][U][C][C][C][U][A][U] = 2.200;
+ int22_ar[G][U][C][C][G][A][A][U] = 2.000;
+ int22_ar[G][U][C][C][G][C][A][U] = 2.000;
+ int22_ar[G][U][C][C][G][G][A][U] = 2.000;
+ int22_ar[G][U][C][C][G][U][A][U] = 2.000;
+ int22_ar[G][U][C][C][U][A][A][U] = 2.200;
+ int22_ar[G][U][C][C][U][C][A][U] = 2.200;
+ int22_ar[G][U][C][C][U][G][A][U] = 2.000;
+ int22_ar[G][U][C][C][U][U][A][U] = 2.200;
+ int22_ar[G][U][C][G][A][A][A][U] = 1.300;
+ int22_ar[G][U][C][G][A][C][A][U] = 2.200;
+ int22_ar[G][U][C][G][A][G][A][U] = 2.000;
+ int22_ar[G][U][C][G][A][U][A][U] = 2.200;
+ int22_ar[G][U][C][G][C][A][A][U] = 2.000;
+ int22_ar[G][U][C][G][C][C][A][U] = 2.000;
+ int22_ar[G][U][C][G][C][G][A][U] = 2.000;
+ int22_ar[G][U][C][G][C][U][A][U] = 2.000;
+ int22_ar[G][U][C][G][G][A][A][U] = 1.800;
+ int22_ar[G][U][C][G][G][C][A][U] = 2.400;
+ int22_ar[G][U][C][G][G][G][A][U] = 2.000;
+ int22_ar[G][U][C][G][G][U][A][U] = 2.400;
+ int22_ar[G][U][C][G][U][A][A][U] = 0.100;
+ int22_ar[G][U][C][G][U][C][A][U] = 1.000;
+ int22_ar[G][U][C][G][U][G][A][U] = 2.000;
+ int22_ar[G][U][C][G][U][U][A][U] = 1.000;
+ int22_ar[G][U][C][U][A][A][A][U] = 2.000;
+ int22_ar[G][U][C][U][A][C][A][U] = 2.000;
+ int22_ar[G][U][C][U][A][G][A][U] = 2.000;
+ int22_ar[G][U][C][U][A][U][A][U] = 2.000;
+ int22_ar[G][U][C][U][C][A][A][U] = 2.200;
+ int22_ar[G][U][C][U][C][C][A][U] = 2.200;
+ int22_ar[G][U][C][U][C][G][A][U] = 2.000;
+ int22_ar[G][U][C][U][C][U][A][U] = 2.200;
+ int22_ar[G][U][C][U][G][A][A][U] = 1.100;
+ int22_ar[G][U][C][U][G][C][A][U] = 2.000;
+ int22_ar[G][U][C][U][G][G][A][U] = 2.000;
+ int22_ar[G][U][C][U][G][U][A][U] = 2.000;
+ int22_ar[G][U][C][U][U][A][A][U] = 1.400;
+ int22_ar[G][U][C][U][U][C][A][U] = 1.400;
+ int22_ar[G][U][C][U][U][G][A][U] = 2.000;
+ int22_ar[G][U][C][U][U][U][A][U] = 1.400;
+ int22_ar[G][U][G][A][A][A][A][U] = 1.500;
+ int22_ar[G][U][G][A][A][C][A][U] = 2.000;
+ int22_ar[G][U][G][A][A][G][A][U] = 2.100;
+ int22_ar[G][U][G][A][A][U][A][U] = 2.300;
+ int22_ar[G][U][G][A][C][A][A][U] = 1.300;
+ int22_ar[G][U][G][A][C][C][A][U] = 2.000;
+ int22_ar[G][U][G][A][C][G][A][U] = 1.800;
+ int22_ar[G][U][G][A][C][U][A][U] = 1.100;
+ int22_ar[G][U][G][A][G][A][A][U] = 0.300;
+ int22_ar[G][U][G][A][G][C][A][U] = 2.000;
+ int22_ar[G][U][G][A][G][G][A][U] = 0.800;
+ int22_ar[G][U][G][A][G][U][A][U] = 1.900;
+ int22_ar[G][U][G][A][U][A][A][U] = 2.000;
+ int22_ar[G][U][G][A][U][C][A][U] = 2.000;
+ int22_ar[G][U][G][A][U][G][A][U] = 2.000;
+ int22_ar[G][U][G][A][U][U][A][U] = 2.000;
+ int22_ar[G][U][G][C][A][A][A][U] = 1.400;
+ int22_ar[G][U][G][C][A][C][A][U] = 2.000;
+ int22_ar[G][U][G][C][A][G][A][U] = 1.900;
+ int22_ar[G][U][G][C][A][U][A][U] = 1.200;
+ int22_ar[G][U][G][C][C][A][A][U] = 2.200;
+ int22_ar[G][U][G][C][C][C][A][U] = 2.000;
+ int22_ar[G][U][G][C][C][G][A][U] = 2.400;
+ int22_ar[G][U][G][C][C][U][A][U] = 2.000;
+ int22_ar[G][U][G][C][G][A][A][U] = 2.000;
+ int22_ar[G][U][G][C][G][C][A][U] = 2.000;
+ int22_ar[G][U][G][C][G][G][A][U] = 2.000;
+ int22_ar[G][U][G][C][G][U][A][U] = 2.000;
+ int22_ar[G][U][G][C][U][A][A][U] = 2.200;
+ int22_ar[G][U][G][C][U][C][A][U] = 2.000;
+ int22_ar[G][U][G][C][U][G][A][U] = 2.400;
+ int22_ar[G][U][G][C][U][U][A][U] = 2.000;
+ int22_ar[G][U][G][G][A][A][A][U] = 0.300;
+ int22_ar[G][U][G][G][A][C][A][U] = 2.000;
+ int22_ar[G][U][G][G][A][G][A][U] = 0.800;
+ int22_ar[G][U][G][G][A][U][A][U] = 1.900;
+ int22_ar[G][U][G][G][C][A][A][U] = 2.000;
+ int22_ar[G][U][G][G][C][C][A][U] = 2.000;
+ int22_ar[G][U][G][G][C][G][A][U] = 2.000;
+ int22_ar[G][U][G][G][C][U][A][U] = 2.000;
+ int22_ar[G][U][G][G][G][A][A][U] = 0.800;
+ int22_ar[G][U][G][G][G][C][A][U] = 2.000;
+ int22_ar[G][U][G][G][G][G][A][U] = 1.400;
+ int22_ar[G][U][G][G][G][U][A][U] = 1.600;
+ int22_ar[G][U][G][G][U][A][A][U] = 0.900;
+ int22_ar[G][U][G][G][U][C][A][U] = 2.000;
+ int22_ar[G][U][G][G][U][G][A][U] = 0.700;
+ int22_ar[G][U][G][G][U][U][A][U] = -1.100;
+ int22_ar[G][U][G][U][A][A][A][U] = 2.000;
+ int22_ar[G][U][G][U][A][C][A][U] = 2.000;
+ int22_ar[G][U][G][U][A][G][A][U] = 2.000;
+ int22_ar[G][U][G][U][A][U][A][U] = 2.000;
+ int22_ar[G][U][G][U][C][A][A][U] = 2.200;
+ int22_ar[G][U][G][U][C][C][A][U] = 2.000;
+ int22_ar[G][U][G][U][C][G][A][U] = 2.400;
+ int22_ar[G][U][G][U][C][U][A][U] = 2.000;
+ int22_ar[G][U][G][U][G][A][A][U] = 1.900;
+ int22_ar[G][U][G][U][G][C][A][U] = 2.000;
+ int22_ar[G][U][G][U][G][G][A][U] = 1.600;
+ int22_ar[G][U][G][U][G][U][A][U] = -0.100;
+ int22_ar[G][U][G][U][U][A][A][U] = 2.200;
+ int22_ar[G][U][G][U][U][C][A][U] = 2.000;
+ int22_ar[G][U][G][U][U][G][A][U] = 2.000;
+ int22_ar[G][U][G][U][U][U][A][U] = 2.000;
+ int22_ar[G][U][U][A][A][A][A][U] = 2.000;
+ int22_ar[G][U][U][A][A][C][A][U] = 3.100;
+ int22_ar[G][U][U][A][A][G][A][U] = 1.300;
+ int22_ar[G][U][U][A][A][U][A][U] = 2.700;
+ int22_ar[G][U][U][A][C][A][A][U] = 2.000;
+ int22_ar[G][U][U][A][C][C][A][U] = 2.200;
+ int22_ar[G][U][U][A][C][G][A][U] = 0.100;
+ int22_ar[G][U][U][A][C][U][A][U] = 1.400;
+ int22_ar[G][U][U][A][G][A][A][U] = 2.000;
+ int22_ar[G][U][U][A][G][C][A][U] = 2.200;
+ int22_ar[G][U][U][A][G][G][A][U] = 0.900;
+ int22_ar[G][U][U][A][G][U][A][U] = 2.200;
+ int22_ar[G][U][U][A][U][A][A][U] = 2.000;
+ int22_ar[G][U][U][A][U][C][A][U] = 2.000;
+ int22_ar[G][U][U][A][U][G][A][U] = 2.000;
+ int22_ar[G][U][U][A][U][U][A][U] = 2.000;
+ int22_ar[G][U][U][C][A][A][A][U] = 2.000;
+ int22_ar[G][U][U][C][A][C][A][U] = 2.300;
+ int22_ar[G][U][U][C][A][G][A][U] = 0.200;
+ int22_ar[G][U][U][C][A][U][A][U] = 1.500;
+ int22_ar[G][U][U][C][C][A][A][U] = 2.000;
+ int22_ar[G][U][U][C][C][C][A][U] = 2.200;
+ int22_ar[G][U][U][C][C][G][A][U] = 1.000;
+ int22_ar[G][U][U][C][C][U][A][U] = 1.400;
+ int22_ar[G][U][U][C][G][A][A][U] = 2.000;
+ int22_ar[G][U][U][C][G][C][A][U] = 2.000;
+ int22_ar[G][U][U][C][G][G][A][U] = 2.000;
+ int22_ar[G][U][U][C][G][U][A][U] = 2.000;
+ int22_ar[G][U][U][C][U][A][A][U] = 2.000;
+ int22_ar[G][U][U][C][U][C][A][U] = 2.200;
+ int22_ar[G][U][U][C][U][G][A][U] = 1.000;
+ int22_ar[G][U][U][C][U][U][A][U] = 1.400;
+ int22_ar[G][U][U][G][A][A][A][U] = 2.000;
+ int22_ar[G][U][U][G][A][C][A][U] = 2.200;
+ int22_ar[G][U][U][G][A][G][A][U] = 0.900;
+ int22_ar[G][U][U][G][A][U][A][U] = 2.200;
+ int22_ar[G][U][U][G][C][A][A][U] = 2.000;
+ int22_ar[G][U][U][G][C][C][A][U] = 2.000;
+ int22_ar[G][U][U][G][C][G][A][U] = 2.000;
+ int22_ar[G][U][U][G][C][U][A][U] = 2.000;
+ int22_ar[G][U][U][G][G][A][A][U] = 2.000;
+ int22_ar[G][U][U][G][G][C][A][U] = 2.400;
+ int22_ar[G][U][U][G][G][G][A][U] = 0.700;
+ int22_ar[G][U][U][G][G][U][A][U] = 2.000;
+ int22_ar[G][U][U][G][U][A][A][U] = 2.000;
+ int22_ar[G][U][U][G][U][C][A][U] = 1.000;
+ int22_ar[G][U][U][G][U][G][A][U] = -2.100;
+ int22_ar[G][U][U][G][U][U][A][U] = 1.100;
+ int22_ar[G][U][U][U][A][A][A][U] = 2.000;
+ int22_ar[G][U][U][U][A][C][A][U] = 2.000;
+ int22_ar[G][U][U][U][A][G][A][U] = 2.000;
+ int22_ar[G][U][U][U][A][U][A][U] = 2.000;
+ int22_ar[G][U][U][U][C][A][A][U] = 2.000;
+ int22_ar[G][U][U][U][C][C][A][U] = 2.200;
+ int22_ar[G][U][U][U][C][G][A][U] = 1.000;
+ int22_ar[G][U][U][U][C][U][A][U] = 1.400;
+ int22_ar[G][U][U][U][G][A][A][U] = 2.000;
+ int22_ar[G][U][U][U][G][C][A][U] = 2.000;
+ int22_ar[G][U][U][U][G][G][A][U] = -1.100;
+ int22_ar[G][U][U][U][G][U][A][U] = 2.000;
+ int22_ar[G][U][U][U][U][A][A][U] = 2.000;
+ int22_ar[G][U][U][U][U][C][A][U] = 1.400;
+ int22_ar[G][U][U][U][U][G][A][U] = 1.100;
+ int22_ar[G][U][U][U][U][U][A][U] = 0.600;
+ int22_ar[G][U][A][A][A][A][C][G] = 2.000;
+ int22_ar[G][U][A][A][A][C][C][G] = 1.900;
+ int22_ar[G][U][A][A][A][G][C][G] = 0.800;
+ int22_ar[G][U][A][A][A][U][C][G] = 2.000;
+ int22_ar[G][U][A][A][C][A][C][G] = 1.900;
+ int22_ar[G][U][A][A][C][C][C][G] = 1.800;
+ int22_ar[G][U][A][A][C][G][C][G] = 0.700;
+ int22_ar[G][U][A][A][C][U][C][G] = 2.000;
+ int22_ar[G][U][A][A][G][A][C][G] = 1.000;
+ int22_ar[G][U][A][A][G][C][C][G] = 0.900;
+ int22_ar[G][U][A][A][G][G][C][G] = -0.200;
+ int22_ar[G][U][A][A][G][U][C][G] = 2.000;
+ int22_ar[G][U][A][A][U][A][C][G] = 2.000;
+ int22_ar[G][U][A][A][U][C][C][G] = 2.000;
+ int22_ar[G][U][A][A][U][G][C][G] = 2.000;
+ int22_ar[G][U][A][A][U][U][C][G] = 2.000;
+ int22_ar[G][U][A][C][A][A][C][G] = 2.400;
+ int22_ar[G][U][A][C][A][C][C][G] = 2.200;
+ int22_ar[G][U][A][C][A][G][C][G] = 1.100;
+ int22_ar[G][U][A][C][A][U][C][G] = 2.000;
+ int22_ar[G][U][A][C][C][A][C][G] = 2.800;
+ int22_ar[G][U][A][C][C][C][C][G] = 2.100;
+ int22_ar[G][U][A][C][C][G][C][G] = 2.000;
+ int22_ar[G][U][A][C][C][U][C][G] = 2.000;
+ int22_ar[G][U][A][C][G][A][C][G] = 2.000;
+ int22_ar[G][U][A][C][G][C][C][G] = 2.000;
+ int22_ar[G][U][A][C][G][G][C][G] = 2.000;
+ int22_ar[G][U][A][C][G][U][C][G] = 2.000;
+ int22_ar[G][U][A][C][U][A][C][G] = 2.700;
+ int22_ar[G][U][A][C][U][C][C][G] = 1.900;
+ int22_ar[G][U][A][C][U][G][C][G] = 1.800;
+ int22_ar[G][U][A][C][U][U][C][G] = 2.000;
+ int22_ar[G][U][A][G][A][A][C][G] = 1.000;
+ int22_ar[G][U][A][G][A][C][C][G] = 0.900;
+ int22_ar[G][U][A][G][A][G][C][G] = -0.200;
+ int22_ar[G][U][A][G][A][U][C][G] = 2.000;
+ int22_ar[G][U][A][G][C][A][C][G] = 2.000;
+ int22_ar[G][U][A][G][C][C][C][G] = 2.000;
+ int22_ar[G][U][A][G][C][G][C][G] = 2.000;
+ int22_ar[G][U][A][G][C][U][C][G] = 2.000;
+ int22_ar[G][U][A][G][G][A][C][G] = 1.800;
+ int22_ar[G][U][A][G][G][C][C][G] = 1.600;
+ int22_ar[G][U][A][G][G][G][C][G] = 0.500;
+ int22_ar[G][U][A][G][G][U][C][G] = 2.000;
+ int22_ar[G][U][A][G][U][A][C][G] = 0.300;
+ int22_ar[G][U][A][G][U][C][C][G] = -0.800;
+ int22_ar[G][U][A][G][U][G][C][G] = -0.100;
+ int22_ar[G][U][A][G][U][U][C][G] = 2.000;
+ int22_ar[G][U][A][U][A][A][C][G] = 2.000;
+ int22_ar[G][U][A][U][A][C][C][G] = 2.000;
+ int22_ar[G][U][A][U][A][G][C][G] = 2.000;
+ int22_ar[G][U][A][U][A][U][C][G] = 2.000;
+ int22_ar[G][U][A][U][C][A][C][G] = 2.700;
+ int22_ar[G][U][A][U][C][C][C][G] = 1.900;
+ int22_ar[G][U][A][U][C][G][C][G] = 1.800;
+ int22_ar[G][U][A][U][C][U][C][G] = 2.000;
+ int22_ar[G][U][A][U][G][A][C][G] = 1.800;
+ int22_ar[G][U][A][U][G][C][C][G] = 0.700;
+ int22_ar[G][U][A][U][G][G][C][G] = 1.400;
+ int22_ar[G][U][A][U][G][U][C][G] = 2.000;
+ int22_ar[G][U][A][U][U][A][C][G] = 2.200;
+ int22_ar[G][U][A][U][U][C][C][G] = 1.000;
+ int22_ar[G][U][A][U][U][G][C][G] = 1.800;
+ int22_ar[G][U][A][U][U][U][C][G] = 2.000;
+ int22_ar[G][U][C][A][A][A][C][G] = 1.800;
+ int22_ar[G][U][C][A][A][C][C][G] = 2.300;
+ int22_ar[G][U][C][A][A][G][C][G] = 2.000;
+ int22_ar[G][U][C][A][A][U][C][G] = 2.300;
+ int22_ar[G][U][C][A][C][A][C][G] = 1.700;
+ int22_ar[G][U][C][A][C][C][C][G] = 1.600;
+ int22_ar[G][U][C][A][C][G][C][G] = 2.000;
+ int22_ar[G][U][C][A][C][U][C][G] = 1.600;
+ int22_ar[G][U][C][A][G][A][C][G] = 0.800;
+ int22_ar[G][U][C][A][G][C][C][G] = 1.700;
+ int22_ar[G][U][C][A][G][G][C][G] = 2.000;
+ int22_ar[G][U][C][A][G][U][C][G] = 1.700;
+ int22_ar[G][U][C][A][U][A][C][G] = 2.000;
+ int22_ar[G][U][C][A][U][C][C][G] = 2.000;
+ int22_ar[G][U][C][A][U][G][C][G] = 2.000;
+ int22_ar[G][U][C][A][U][U][C][G] = 2.000;
+ int22_ar[G][U][C][C][A][A][C][G] = 2.100;
+ int22_ar[G][U][C][C][A][C][C][G] = 2.100;
+ int22_ar[G][U][C][C][A][G][C][G] = 2.000;
+ int22_ar[G][U][C][C][A][U][C][G] = 2.100;
+ int22_ar[G][U][C][C][C][A][C][G] = 2.000;
+ int22_ar[G][U][C][C][C][C][C][G] = 1.900;
+ int22_ar[G][U][C][C][C][G][C][G] = 2.000;
+ int22_ar[G][U][C][C][C][U][C][G] = 1.900;
+ int22_ar[G][U][C][C][G][A][C][G] = 2.000;
+ int22_ar[G][U][C][C][G][C][C][G] = 2.000;
+ int22_ar[G][U][C][C][G][G][C][G] = 2.000;
+ int22_ar[G][U][C][C][G][U][C][G] = 2.000;
+ int22_ar[G][U][C][C][U][A][C][G] = 1.800;
+ int22_ar[G][U][C][C][U][C][C][G] = 1.800;
+ int22_ar[G][U][C][C][U][G][C][G] = 2.000;
+ int22_ar[G][U][C][C][U][U][C][G] = 1.800;
+ int22_ar[G][U][C][G][A][A][C][G] = 0.800;
+ int22_ar[G][U][C][G][A][C][C][G] = 1.700;
+ int22_ar[G][U][C][G][A][G][C][G] = 2.000;
+ int22_ar[G][U][C][G][A][U][C][G] = 1.700;
+ int22_ar[G][U][C][G][C][A][C][G] = 2.000;
+ int22_ar[G][U][C][G][C][C][C][G] = 2.000;
+ int22_ar[G][U][C][G][C][G][C][G] = 2.000;
+ int22_ar[G][U][C][G][C][U][C][G] = 2.000;
+ int22_ar[G][U][C][G][G][A][C][G] = 1.500;
+ int22_ar[G][U][C][G][G][C][C][G] = 2.100;
+ int22_ar[G][U][C][G][G][G][C][G] = 2.000;
+ int22_ar[G][U][C][G][G][U][C][G] = 2.100;
+ int22_ar[G][U][C][G][U][A][C][G] = -0.900;
+ int22_ar[G][U][C][G][U][C][C][G] = 0.000;
+ int22_ar[G][U][C][G][U][G][C][G] = 2.000;
+ int22_ar[G][U][C][G][U][U][C][G] = 0.000;
+ int22_ar[G][U][C][U][A][A][C][G] = 2.000;
+ int22_ar[G][U][C][U][A][C][C][G] = 2.000;
+ int22_ar[G][U][C][U][A][G][C][G] = 2.000;
+ int22_ar[G][U][C][U][A][U][C][G] = 2.000;
+ int22_ar[G][U][C][U][C][A][C][G] = 1.800;
+ int22_ar[G][U][C][U][C][C][C][G] = 1.800;
+ int22_ar[G][U][C][U][C][G][C][G] = 2.000;
+ int22_ar[G][U][C][U][C][U][C][G] = 1.800;
+ int22_ar[G][U][C][U][G][A][C][G] = 0.600;
+ int22_ar[G][U][C][U][G][C][C][G] = 1.500;
+ int22_ar[G][U][C][U][G][G][C][G] = 2.000;
+ int22_ar[G][U][C][U][G][U][C][G] = 1.500;
+ int22_ar[G][U][C][U][U][A][C][G] = 0.900;
+ int22_ar[G][U][C][U][U][C][C][G] = 0.900;
+ int22_ar[G][U][C][U][U][G][C][G] = 2.000;
+ int22_ar[G][U][C][U][U][U][C][G] = 0.900;
+ int22_ar[G][U][G][A][A][A][C][G] = 0.800;
+ int22_ar[G][U][G][A][A][C][C][G] = 2.000;
+ int22_ar[G][U][G][A][A][G][C][G] = 1.300;
+ int22_ar[G][U][G][A][A][U][C][G] = 1.600;
+ int22_ar[G][U][G][A][C][A][C][G] = 0.700;
+ int22_ar[G][U][G][A][C][C][C][G] = 2.000;
+ int22_ar[G][U][G][A][C][G][C][G] = 1.200;
+ int22_ar[G][U][G][A][C][U][C][G] = 0.500;
+ int22_ar[G][U][G][A][G][A][C][G] = -0.200;
+ int22_ar[G][U][G][A][G][C][C][G] = 2.000;
+ int22_ar[G][U][G][A][G][G][C][G] = 0.300;
+ int22_ar[G][U][G][A][G][U][C][G] = 1.400;
+ int22_ar[G][U][G][A][U][A][C][G] = 2.000;
+ int22_ar[G][U][G][A][U][C][C][G] = 2.000;
+ int22_ar[G][U][G][A][U][G][C][G] = 2.000;
+ int22_ar[G][U][G][A][U][U][C][G] = 2.000;
+ int22_ar[G][U][G][C][A][A][C][G] = 1.100;
+ int22_ar[G][U][G][C][A][C][C][G] = 2.000;
+ int22_ar[G][U][G][C][A][G][C][G] = 1.700;
+ int22_ar[G][U][G][C][A][U][C][G] = 0.900;
+ int22_ar[G][U][G][C][C][A][C][G] = 2.000;
+ int22_ar[G][U][G][C][C][C][C][G] = 2.000;
+ int22_ar[G][U][G][C][C][G][C][G] = 2.100;
+ int22_ar[G][U][G][C][C][U][C][G] = 1.800;
+ int22_ar[G][U][G][C][G][A][C][G] = 2.000;
+ int22_ar[G][U][G][C][G][C][C][G] = 2.000;
+ int22_ar[G][U][G][C][G][G][C][G] = 2.000;
+ int22_ar[G][U][G][C][G][U][C][G] = 2.000;
+ int22_ar[G][U][G][C][U][A][C][G] = 1.800;
+ int22_ar[G][U][G][C][U][C][C][G] = 2.000;
+ int22_ar[G][U][G][C][U][G][C][G] = 2.000;
+ int22_ar[G][U][G][C][U][U][C][G] = 1.600;
+ int22_ar[G][U][G][G][A][A][C][G] = -0.200;
+ int22_ar[G][U][G][G][A][C][C][G] = 2.000;
+ int22_ar[G][U][G][G][A][G][C][G] = 0.300;
+ int22_ar[G][U][G][G][A][U][C][G] = 1.400;
+ int22_ar[G][U][G][G][C][A][C][G] = 2.000;
+ int22_ar[G][U][G][G][C][C][C][G] = 2.000;
+ int22_ar[G][U][G][G][C][G][C][G] = 2.000;
+ int22_ar[G][U][G][G][C][U][C][G] = 2.000;
+ int22_ar[G][U][G][G][G][A][C][G] = 0.500;
+ int22_ar[G][U][G][G][G][C][C][G] = 2.000;
+ int22_ar[G][U][G][G][G][G][C][G] = 1.100;
+ int22_ar[G][U][G][G][G][U][C][G] = 1.300;
+ int22_ar[G][U][G][G][U][A][C][G] = -0.100;
+ int22_ar[G][U][G][G][U][C][C][G] = 2.000;
+ int22_ar[G][U][G][G][U][G][C][G] = -0.400;
+ int22_ar[G][U][G][G][U][U][C][G] = -2.100;
+ int22_ar[G][U][G][U][A][A][C][G] = 2.000;
+ int22_ar[G][U][G][U][A][C][C][G] = 2.000;
+ int22_ar[G][U][G][U][A][G][C][G] = 2.000;
+ int22_ar[G][U][G][U][A][U][C][G] = 2.000;
+ int22_ar[G][U][G][U][C][A][C][G] = 1.800;
+ int22_ar[G][U][G][U][C][C][C][G] = 2.000;
+ int22_ar[G][U][G][U][C][G][C][G] = 2.000;
+ int22_ar[G][U][G][U][C][U][C][G] = 1.600;
+ int22_ar[G][U][G][U][G][A][C][G] = 1.400;
+ int22_ar[G][U][G][U][G][C][C][G] = 2.000;
+ int22_ar[G][U][G][U][G][G][C][G] = 1.100;
+ int22_ar[G][U][G][U][G][U][C][G] = -0.600;
+ int22_ar[G][U][G][U][U][A][C][G] = 1.800;
+ int22_ar[G][U][G][U][U][C][C][G] = 2.000;
+ int22_ar[G][U][G][U][U][G][C][G] = 1.500;
+ int22_ar[G][U][G][U][U][U][C][G] = 1.600;
+ int22_ar[G][U][U][A][A][A][C][G] = 2.000;
+ int22_ar[G][U][U][A][A][C][C][G] = 2.300;
+ int22_ar[G][U][U][A][A][G][C][G] = 0.600;
+ int22_ar[G][U][U][A][A][U][C][G] = 1.900;
+ int22_ar[G][U][U][A][C][A][C][G] = 2.000;
+ int22_ar[G][U][U][A][C][C][C][G] = 1.600;
+ int22_ar[G][U][U][A][C][G][C][G] = -0.500;
+ int22_ar[G][U][U][A][C][U][C][G] = 0.800;
+ int22_ar[G][U][U][A][G][A][C][G] = 2.000;
+ int22_ar[G][U][U][A][G][C][C][G] = 1.700;
+ int22_ar[G][U][U][A][G][G][C][G] = 0.400;
+ int22_ar[G][U][U][A][G][U][C][G] = 1.800;
+ int22_ar[G][U][U][A][U][A][C][G] = 2.000;
+ int22_ar[G][U][U][A][U][C][C][G] = 2.000;
+ int22_ar[G][U][U][A][U][G][C][G] = 2.000;
+ int22_ar[G][U][U][A][U][U][C][G] = 2.000;
+ int22_ar[G][U][U][C][A][A][C][G] = 2.000;
+ int22_ar[G][U][U][C][A][C][C][G] = 2.100;
+ int22_ar[G][U][U][C][A][G][C][G] = 0.000;
+ int22_ar[G][U][U][C][A][U][C][G] = 1.300;
+ int22_ar[G][U][U][C][C][A][C][G] = 2.000;
+ int22_ar[G][U][U][C][C][C][C][G] = 1.900;
+ int22_ar[G][U][U][C][C][G][C][G] = 0.800;
+ int22_ar[G][U][U][C][C][U][C][G] = 1.100;
+ int22_ar[G][U][U][C][G][A][C][G] = 2.000;
+ int22_ar[G][U][U][C][G][C][C][G] = 2.000;
+ int22_ar[G][U][U][C][G][G][C][G] = 2.000;
+ int22_ar[G][U][U][C][G][U][C][G] = 2.000;
+ int22_ar[G][U][U][C][U][A][C][G] = 2.000;
+ int22_ar[G][U][U][C][U][C][C][G] = 1.800;
+ int22_ar[G][U][U][C][U][G][C][G] = 0.700;
+ int22_ar[G][U][U][C][U][U][C][G] = 1.000;
+ int22_ar[G][U][U][G][A][A][C][G] = 2.000;
+ int22_ar[G][U][U][G][A][C][C][G] = 1.700;
+ int22_ar[G][U][U][G][A][G][C][G] = 0.400;
+ int22_ar[G][U][U][G][A][U][C][G] = 1.800;
+ int22_ar[G][U][U][G][C][A][C][G] = 2.000;
+ int22_ar[G][U][U][G][C][C][C][G] = 2.000;
+ int22_ar[G][U][U][G][C][G][C][G] = 2.000;
+ int22_ar[G][U][U][G][C][U][C][G] = 2.000;
+ int22_ar[G][U][U][G][G][A][C][G] = 2.000;
+ int22_ar[G][U][U][G][G][C][C][G] = 2.100;
+ int22_ar[G][U][U][G][G][G][C][G] = 0.400;
+ int22_ar[G][U][U][G][G][U][C][G] = 1.700;
+ int22_ar[G][U][U][G][U][A][C][G] = 2.000;
+ int22_ar[G][U][U][G][U][C][C][G] = 0.000;
+ int22_ar[G][U][U][G][U][G][C][G] = -3.100;
+ int22_ar[G][U][U][G][U][U][C][G] = 0.000;
+ int22_ar[G][U][U][U][A][A][C][G] = 2.000;
+ int22_ar[G][U][U][U][A][C][C][G] = 2.000;
+ int22_ar[G][U][U][U][A][G][C][G] = 2.000;
+ int22_ar[G][U][U][U][A][U][C][G] = 2.000;
+ int22_ar[G][U][U][U][C][A][C][G] = 2.000;
+ int22_ar[G][U][U][U][C][C][C][G] = 1.800;
+ int22_ar[G][U][U][U][C][G][C][G] = 0.700;
+ int22_ar[G][U][U][U][C][U][C][G] = 1.000;
+ int22_ar[G][U][U][U][G][A][C][G] = 2.000;
+ int22_ar[G][U][U][U][G][C][C][G] = 1.500;
+ int22_ar[G][U][U][U][G][G][C][G] = -1.600;
+ int22_ar[G][U][U][U][G][U][C][G] = 1.600;
+ int22_ar[G][U][U][U][U][A][C][G] = 2.000;
+ int22_ar[G][U][U][U][U][C][C][G] = 0.900;
+ int22_ar[G][U][U][U][U][G][C][G] = 0.600;
+ int22_ar[G][U][U][U][U][U][C][G] = 0.100;
+ int22_ar[G][U][A][A][A][A][G][C] = 2.100;
+ int22_ar[G][U][A][A][A][C][G][C] = 2.000;
+ int22_ar[G][U][A][A][A][G][G][C] = 0.900;
+ int22_ar[G][U][A][A][A][U][G][C] = 2.000;
+ int22_ar[G][U][A][A][C][A][G][C] = 1.900;
+ int22_ar[G][U][A][A][C][C][G][C] = 1.700;
+ int22_ar[G][U][A][A][C][G][G][C] = 0.600;
+ int22_ar[G][U][A][A][C][U][G][C] = 2.000;
+ int22_ar[G][U][A][A][G][A][G][C] = 0.100;
+ int22_ar[G][U][A][A][G][C][G][C] = 0.000;
+ int22_ar[G][U][A][A][G][G][G][C] = -1.100;
+ int22_ar[G][U][A][A][G][U][G][C] = 2.000;
+ int22_ar[G][U][A][A][U][A][G][C] = 2.000;
+ int22_ar[G][U][A][A][U][C][G][C] = 2.000;
+ int22_ar[G][U][A][A][U][G][G][C] = 2.000;
+ int22_ar[G][U][A][A][U][U][G][C] = 2.000;
+ int22_ar[G][U][A][C][A][A][G][C] = 1.800;
+ int22_ar[G][U][A][C][A][C][G][C] = 1.700;
+ int22_ar[G][U][A][C][A][G][G][C] = 0.600;
+ int22_ar[G][U][A][C][A][U][G][C] = 2.000;
+ int22_ar[G][U][A][C][C][A][G][C] = 2.500;
+ int22_ar[G][U][A][C][C][C][G][C] = 1.700;
+ int22_ar[G][U][A][C][C][G][G][C] = 1.600;
+ int22_ar[G][U][A][C][C][U][G][C] = 2.000;
+ int22_ar[G][U][A][C][G][A][G][C] = 2.000;
+ int22_ar[G][U][A][C][G][C][G][C] = 2.000;
+ int22_ar[G][U][A][C][G][G][G][C] = 2.000;
+ int22_ar[G][U][A][C][G][U][G][C] = 2.000;
+ int22_ar[G][U][A][C][U][A][G][C] = 1.500;
+ int22_ar[G][U][A][C][U][C][G][C] = 0.700;
+ int22_ar[G][U][A][C][U][G][G][C] = 0.700;
+ int22_ar[G][U][A][C][U][U][G][C] = 2.000;
+ int22_ar[G][U][A][G][A][A][G][C] = 0.700;
+ int22_ar[G][U][A][G][A][C][G][C] = 0.600;
+ int22_ar[G][U][A][G][A][G][G][C] = -0.500;
+ int22_ar[G][U][A][G][A][U][G][C] = 2.000;
+ int22_ar[G][U][A][G][C][A][G][C] = 2.000;
+ int22_ar[G][U][A][G][C][C][G][C] = 2.000;
+ int22_ar[G][U][A][G][C][G][G][C] = 2.000;
+ int22_ar[G][U][A][G][C][U][G][C] = 2.000;
+ int22_ar[G][U][A][G][G][A][G][C] = 1.800;
+ int22_ar[G][U][A][G][G][C][G][C] = 1.600;
+ int22_ar[G][U][A][G][G][G][G][C] = 0.500;
+ int22_ar[G][U][A][G][G][U][G][C] = 2.000;
+ int22_ar[G][U][A][G][U][A][G][C] = 0.000;
+ int22_ar[G][U][A][G][U][C][G][C] = -1.200;
+ int22_ar[G][U][A][G][U][G][G][C] = -0.500;
+ int22_ar[G][U][A][G][U][U][G][C] = 2.000;
+ int22_ar[G][U][A][U][A][A][G][C] = 2.000;
+ int22_ar[G][U][A][U][A][C][G][C] = 2.000;
+ int22_ar[G][U][A][U][A][G][G][C] = 2.000;
+ int22_ar[G][U][A][U][A][U][G][C] = 2.000;
+ int22_ar[G][U][A][U][C][A][G][C] = 2.500;
+ int22_ar[G][U][A][U][C][C][G][C] = 1.800;
+ int22_ar[G][U][A][U][C][G][G][C] = 1.700;
+ int22_ar[G][U][A][U][C][U][G][C] = 2.000;
+ int22_ar[G][U][A][U][G][A][G][C] = 0.400;
+ int22_ar[G][U][A][U][G][C][G][C] = -0.800;
+ int22_ar[G][U][A][U][G][G][G][C] = -0.100;
+ int22_ar[G][U][A][U][G][U][G][C] = 2.000;
+ int22_ar[G][U][A][U][U][A][G][C] = 2.100;
+ int22_ar[G][U][A][U][U][C][G][C] = 1.000;
+ int22_ar[G][U][A][U][U][G][G][C] = 1.700;
+ int22_ar[G][U][A][U][U][U][G][C] = 2.000;
+ int22_ar[G][U][C][A][A][A][G][C] = 1.900;
+ int22_ar[G][U][C][A][A][C][G][C] = 2.400;
+ int22_ar[G][U][C][A][A][G][G][C] = 2.000;
+ int22_ar[G][U][C][A][A][U][G][C] = 2.400;
+ int22_ar[G][U][C][A][C][A][G][C] = 1.600;
+ int22_ar[G][U][C][A][C][C][G][C] = 1.600;
+ int22_ar[G][U][C][A][C][G][G][C] = 2.000;
+ int22_ar[G][U][C][A][C][U][G][C] = 1.600;
+ int22_ar[G][U][C][A][G][A][G][C] = -0.100;
+ int22_ar[G][U][C][A][G][C][G][C] = 0.800;
+ int22_ar[G][U][C][A][G][G][G][C] = 2.000;
+ int22_ar[G][U][C][A][G][U][G][C] = 0.800;
+ int22_ar[G][U][C][A][U][A][G][C] = 2.000;
+ int22_ar[G][U][C][A][U][C][G][C] = 2.000;
+ int22_ar[G][U][C][A][U][G][G][C] = 2.000;
+ int22_ar[G][U][C][A][U][U][G][C] = 2.000;
+ int22_ar[G][U][C][C][A][A][G][C] = 1.600;
+ int22_ar[G][U][C][C][A][C][G][C] = 1.500;
+ int22_ar[G][U][C][C][A][G][G][C] = 2.000;
+ int22_ar[G][U][C][C][A][U][G][C] = 1.500;
+ int22_ar[G][U][C][C][C][A][G][C] = 1.600;
+ int22_ar[G][U][C][C][C][C][G][C] = 1.600;
+ int22_ar[G][U][C][C][C][G][G][C] = 2.000;
+ int22_ar[G][U][C][C][C][U][G][C] = 1.600;
+ int22_ar[G][U][C][C][G][A][G][C] = 2.000;
+ int22_ar[G][U][C][C][G][C][G][C] = 2.000;
+ int22_ar[G][U][C][C][G][G][G][C] = 2.000;
+ int22_ar[G][U][C][C][G][U][G][C] = 2.000;
+ int22_ar[G][U][C][C][U][A][G][C] = 0.600;
+ int22_ar[G][U][C][C][U][C][G][C] = 0.600;
+ int22_ar[G][U][C][C][U][G][G][C] = 2.000;
+ int22_ar[G][U][C][C][U][U][G][C] = 0.600;
+ int22_ar[G][U][C][G][A][A][G][C] = 0.500;
+ int22_ar[G][U][C][G][A][C][G][C] = 1.400;
+ int22_ar[G][U][C][G][A][G][G][C] = 2.000;
+ int22_ar[G][U][C][G][A][U][G][C] = 1.400;
+ int22_ar[G][U][C][G][C][A][G][C] = 2.000;
+ int22_ar[G][U][C][G][C][C][G][C] = 2.000;
+ int22_ar[G][U][C][G][C][G][G][C] = 2.000;
+ int22_ar[G][U][C][G][C][U][G][C] = 2.000;
+ int22_ar[G][U][C][G][G][A][G][C] = 1.500;
+ int22_ar[G][U][C][G][G][C][G][C] = 2.100;
+ int22_ar[G][U][C][G][G][G][G][C] = 2.000;
+ int22_ar[G][U][C][G][G][U][G][C] = 2.100;
+ int22_ar[G][U][C][G][U][A][G][C] = -1.300;
+ int22_ar[G][U][C][G][U][C][G][C] = -0.300;
+ int22_ar[G][U][C][G][U][G][G][C] = 2.000;
+ int22_ar[G][U][C][G][U][U][G][C] = -0.300;
+ int22_ar[G][U][C][U][A][A][G][C] = 2.000;
+ int22_ar[G][U][C][U][A][C][G][C] = 2.000;
+ int22_ar[G][U][C][U][A][G][G][C] = 2.000;
+ int22_ar[G][U][C][U][A][U][G][C] = 2.000;
+ int22_ar[G][U][C][U][C][A][G][C] = 1.700;
+ int22_ar[G][U][C][U][C][C][G][C] = 1.600;
+ int22_ar[G][U][C][U][C][G][G][C] = 2.000;
+ int22_ar[G][U][C][U][C][U][G][C] = 1.600;
+ int22_ar[G][U][C][U][G][A][G][C] = -0.900;
+ int22_ar[G][U][C][U][G][C][G][C] = 0.100;
+ int22_ar[G][U][C][U][G][G][G][C] = 2.000;
+ int22_ar[G][U][C][U][G][U][G][C] = 0.100;
+ int22_ar[G][U][C][U][U][A][G][C] = 0.900;
+ int22_ar[G][U][C][U][U][C][G][C] = 0.800;
+ int22_ar[G][U][C][U][U][G][G][C] = 2.000;
+ int22_ar[G][U][C][U][U][U][G][C] = 0.800;
+ int22_ar[G][U][G][A][A][A][G][C] = 0.900;
+ int22_ar[G][U][G][A][A][C][G][C] = 2.000;
+ int22_ar[G][U][G][A][A][G][G][C] = 1.400;
+ int22_ar[G][U][G][A][A][U][G][C] = 1.700;
+ int22_ar[G][U][G][A][C][A][G][C] = 0.600;
+ int22_ar[G][U][G][A][C][C][G][C] = 2.000;
+ int22_ar[G][U][G][A][C][G][G][C] = 1.200;
+ int22_ar[G][U][G][A][C][U][G][C] = 0.400;
+ int22_ar[G][U][G][A][G][A][G][C] = -1.100;
+ int22_ar[G][U][G][A][G][C][G][C] = 2.000;
+ int22_ar[G][U][G][A][G][G][G][C] = -0.600;
+ int22_ar[G][U][G][A][G][U][G][C] = 0.500;
+ int22_ar[G][U][G][A][U][A][G][C] = 2.000;
+ int22_ar[G][U][G][A][U][C][G][C] = 2.000;
+ int22_ar[G][U][G][A][U][G][G][C] = 2.000;
+ int22_ar[G][U][G][A][U][U][G][C] = 2.000;
+ int22_ar[G][U][G][C][A][A][G][C] = 0.600;
+ int22_ar[G][U][G][C][A][C][G][C] = 2.000;
+ int22_ar[G][U][G][C][A][G][G][C] = 1.100;
+ int22_ar[G][U][G][C][A][U][G][C] = 0.400;
+ int22_ar[G][U][G][C][C][A][G][C] = 1.600;
+ int22_ar[G][U][G][C][C][C][G][C] = 2.000;
+ int22_ar[G][U][G][C][C][G][G][C] = 1.800;
+ int22_ar[G][U][G][C][C][U][G][C] = 1.400;
+ int22_ar[G][U][G][C][G][A][G][C] = 2.000;
+ int22_ar[G][U][G][C][G][C][G][C] = 2.000;
+ int22_ar[G][U][G][C][G][G][G][C] = 2.000;
+ int22_ar[G][U][G][C][G][U][G][C] = 2.000;
+ int22_ar[G][U][G][C][U][A][G][C] = 0.700;
+ int22_ar[G][U][G][C][U][C][G][C] = 2.000;
+ int22_ar[G][U][G][C][U][G][G][C] = 0.800;
+ int22_ar[G][U][G][C][U][U][G][C] = 0.500;
+ int22_ar[G][U][G][G][A][A][G][C] = -0.500;
+ int22_ar[G][U][G][G][A][C][G][C] = 2.000;
+ int22_ar[G][U][G][G][A][G][G][C] = 0.000;
+ int22_ar[G][U][G][G][A][U][G][C] = 1.100;
+ int22_ar[G][U][G][G][C][A][G][C] = 2.000;
+ int22_ar[G][U][G][G][C][C][G][C] = 2.000;
+ int22_ar[G][U][G][G][C][G][G][C] = 2.000;
+ int22_ar[G][U][G][G][C][U][G][C] = 2.000;
+ int22_ar[G][U][G][G][G][A][G][C] = 0.500;
+ int22_ar[G][U][G][G][G][C][G][C] = 2.000;
+ int22_ar[G][U][G][G][G][G][G][C] = 1.100;
+ int22_ar[G][U][G][G][G][U][G][C] = 1.300;
+ int22_ar[G][U][G][G][U][A][G][C] = -0.500;
+ int22_ar[G][U][G][G][U][C][G][C] = 2.000;
+ int22_ar[G][U][G][G][U][G][G][C] = -0.700;
+ int22_ar[G][U][G][G][U][U][G][C] = -2.500;
+ int22_ar[G][U][G][U][A][A][G][C] = 2.000;
+ int22_ar[G][U][G][U][A][C][G][C] = 2.000;
+ int22_ar[G][U][G][U][A][G][G][C] = 2.000;
+ int22_ar[G][U][G][U][A][U][G][C] = 2.000;
+ int22_ar[G][U][G][U][C][A][G][C] = 1.700;
+ int22_ar[G][U][G][U][C][C][G][C] = 2.000;
+ int22_ar[G][U][G][U][C][G][G][C] = 1.800;
+ int22_ar[G][U][G][U][C][U][G][C] = 1.500;
+ int22_ar[G][U][G][U][G][A][G][C] = -0.100;
+ int22_ar[G][U][G][U][G][C][G][C] = 2.000;
+ int22_ar[G][U][G][U][G][G][G][C] = -0.300;
+ int22_ar[G][U][G][U][G][U][G][C] = -2.100;
+ int22_ar[G][U][G][U][U][A][G][C] = 1.700;
+ int22_ar[G][U][G][U][U][C][G][C] = 2.000;
+ int22_ar[G][U][G][U][U][G][G][C] = 1.400;
+ int22_ar[G][U][G][U][U][U][G][C] = 1.500;
+ int22_ar[G][U][U][A][A][A][G][C] = 2.000;
+ int22_ar[G][U][U][A][A][C][G][C] = 2.400;
+ int22_ar[G][U][U][A][A][G][G][C] = 0.700;
+ int22_ar[G][U][U][A][A][U][G][C] = 2.000;
+ int22_ar[G][U][U][A][C][A][G][C] = 2.000;
+ int22_ar[G][U][U][A][C][C][G][C] = 1.600;
+ int22_ar[G][U][U][A][C][G][G][C] = -0.500;
+ int22_ar[G][U][U][A][C][U][G][C] = 0.800;
+ int22_ar[G][U][U][A][G][A][G][C] = 2.000;
+ int22_ar[G][U][U][A][G][C][G][C] = 0.800;
+ int22_ar[G][U][U][A][G][G][G][C] = -0.500;
+ int22_ar[G][U][U][A][G][U][G][C] = 0.800;
+ int22_ar[G][U][U][A][U][A][G][C] = 2.000;
+ int22_ar[G][U][U][A][U][C][G][C] = 2.000;
+ int22_ar[G][U][U][A][U][G][G][C] = 2.000;
+ int22_ar[G][U][U][A][U][U][G][C] = 2.000;
+ int22_ar[G][U][U][C][A][A][G][C] = 2.000;
+ int22_ar[G][U][U][C][A][C][G][C] = 1.500;
+ int22_ar[G][U][U][C][A][G][G][C] = -0.600;
+ int22_ar[G][U][U][C][A][U][G][C] = 0.700;
+ int22_ar[G][U][U][C][C][A][G][C] = 2.000;
+ int22_ar[G][U][U][C][C][C][G][C] = 1.600;
+ int22_ar[G][U][U][C][C][G][G][C] = 0.500;
+ int22_ar[G][U][U][C][C][U][G][C] = 0.800;
+ int22_ar[G][U][U][C][G][A][G][C] = 2.000;
+ int22_ar[G][U][U][C][G][C][G][C] = 2.000;
+ int22_ar[G][U][U][C][G][G][G][C] = 2.000;
+ int22_ar[G][U][U][C][G][U][G][C] = 2.000;
+ int22_ar[G][U][U][C][U][A][G][C] = 2.000;
+ int22_ar[G][U][U][C][U][C][G][C] = 0.600;
+ int22_ar[G][U][U][C][U][G][G][C] = -0.500;
+ int22_ar[G][U][U][C][U][U][G][C] = -0.200;
+ int22_ar[G][U][U][G][A][A][G][C] = 2.000;
+ int22_ar[G][U][U][G][A][C][G][C] = 1.400;
+ int22_ar[G][U][U][G][A][G][G][C] = 0.100;
+ int22_ar[G][U][U][G][A][U][G][C] = 1.500;
+ int22_ar[G][U][U][G][C][A][G][C] = 2.000;
+ int22_ar[G][U][U][G][C][C][G][C] = 2.000;
+ int22_ar[G][U][U][G][C][G][G][C] = 2.000;
+ int22_ar[G][U][U][G][C][U][G][C] = 2.000;
+ int22_ar[G][U][U][G][G][A][G][C] = 2.000;
+ int22_ar[G][U][U][G][G][C][G][C] = 2.100;
+ int22_ar[G][U][U][G][G][G][G][C] = 0.400;
+ int22_ar[G][U][U][G][G][U][G][C] = 1.700;
+ int22_ar[G][U][U][G][U][A][G][C] = 2.000;
+ int22_ar[G][U][U][G][U][C][G][C] = -0.300;
+ int22_ar[G][U][U][G][U][G][G][C] = -3.500;
+ int22_ar[G][U][U][G][U][U][G][C] = -0.300;
+ int22_ar[G][U][U][U][A][A][G][C] = 2.000;
+ int22_ar[G][U][U][U][A][C][G][C] = 2.000;
+ int22_ar[G][U][U][U][A][G][G][C] = 2.000;
+ int22_ar[G][U][U][U][A][U][G][C] = 2.000;
+ int22_ar[G][U][U][U][C][A][G][C] = 2.000;
+ int22_ar[G][U][U][U][C][C][G][C] = 1.600;
+ int22_ar[G][U][U][U][C][G][G][C] = 0.500;
+ int22_ar[G][U][U][U][C][U][G][C] = 0.800;
+ int22_ar[G][U][U][U][G][A][G][C] = 2.000;
+ int22_ar[G][U][U][U][G][C][G][C] = 0.100;
+ int22_ar[G][U][U][U][G][G][G][C] = -3.100;
+ int22_ar[G][U][U][U][G][U][G][C] = 0.100;
+ int22_ar[G][U][U][U][U][A][G][C] = 2.000;
+ int22_ar[G][U][U][U][U][C][G][C] = 0.800;
+ int22_ar[G][U][U][U][U][G][G][C] = 0.500;
+ int22_ar[G][U][U][U][U][U][G][C] = 0.000;
+ int22_ar[G][U][A][A][A][A][G][U] = 2.800;
+ int22_ar[G][U][A][A][A][C][G][U] = 2.600;
+ int22_ar[G][U][A][A][A][G][G][U] = 1.500;
+ int22_ar[G][U][A][A][A][U][G][U] = 2.000;
+ int22_ar[G][U][A][A][C][A][G][U] = 2.500;
+ int22_ar[G][U][A][A][C][C][G][U] = 2.400;
+ int22_ar[G][U][A][A][C][G][G][U] = 1.300;
+ int22_ar[G][U][A][A][C][U][G][U] = 2.000;
+ int22_ar[G][U][A][A][G][A][G][U] = 1.500;
+ int22_ar[G][U][A][A][G][C][G][U] = 1.400;
+ int22_ar[G][U][A][A][G][G][G][U] = 0.300;
+ int22_ar[G][U][A][A][G][U][G][U] = 2.000;
+ int22_ar[G][U][A][A][U][A][G][U] = 2.000;
+ int22_ar[G][U][A][A][U][C][G][U] = 2.000;
+ int22_ar[G][U][A][A][U][G][G][U] = 2.000;
+ int22_ar[G][U][A][A][U][U][G][U] = 2.000;
+ int22_ar[G][U][A][C][A][A][G][U] = 2.600;
+ int22_ar[G][U][A][C][A][C][G][U] = 2.500;
+ int22_ar[G][U][A][C][A][G][G][U] = 1.400;
+ int22_ar[G][U][A][C][A][U][G][U] = 2.000;
+ int22_ar[G][U][A][C][C][A][G][U] = 3.100;
+ int22_ar[G][U][A][C][C][C][G][U] = 2.300;
+ int22_ar[G][U][A][C][C][G][G][U] = 2.200;
+ int22_ar[G][U][A][C][C][U][G][U] = 2.000;
+ int22_ar[G][U][A][C][G][A][G][U] = 2.000;
+ int22_ar[G][U][A][C][G][C][G][U] = 2.000;
+ int22_ar[G][U][A][C][G][G][G][U] = 2.000;
+ int22_ar[G][U][A][C][G][U][G][U] = 2.000;
+ int22_ar[G][U][A][C][U][A][G][U] = 3.100;
+ int22_ar[G][U][A][C][U][C][G][U] = 2.300;
+ int22_ar[G][U][A][C][U][G][G][U] = 2.200;
+ int22_ar[G][U][A][C][U][U][G][U] = 2.000;
+ int22_ar[G][U][A][G][A][A][G][U] = 1.500;
+ int22_ar[G][U][A][G][A][C][G][U] = 1.400;
+ int22_ar[G][U][A][G][A][G][G][U] = 0.300;
+ int22_ar[G][U][A][G][A][U][G][U] = 2.000;
+ int22_ar[G][U][A][G][C][A][G][U] = 2.000;
+ int22_ar[G][U][A][G][C][C][G][U] = 2.000;
+ int22_ar[G][U][A][G][C][G][G][U] = 2.000;
+ int22_ar[G][U][A][G][C][U][G][U] = 2.000;
+ int22_ar[G][U][A][G][G][A][G][U] = 2.100;
+ int22_ar[G][U][A][G][G][C][G][U] = 1.900;
+ int22_ar[G][U][A][G][G][G][G][U] = 0.800;
+ int22_ar[G][U][A][G][G][U][G][U] = 2.000;
+ int22_ar[G][U][A][G][U][A][G][U] = 1.300;
+ int22_ar[G][U][A][G][U][C][G][U] = 0.200;
+ int22_ar[G][U][A][G][U][G][G][U] = 0.900;
+ int22_ar[G][U][A][G][U][U][G][U] = 2.000;
+ int22_ar[G][U][A][U][A][A][G][U] = 2.000;
+ int22_ar[G][U][A][U][A][C][G][U] = 2.000;
+ int22_ar[G][U][A][U][A][G][G][U] = 2.000;
+ int22_ar[G][U][A][U][A][U][G][U] = 2.000;
+ int22_ar[G][U][A][U][C][A][G][U] = 3.100;
+ int22_ar[G][U][A][U][C][C][G][U] = 2.300;
+ int22_ar[G][U][A][U][C][G][G][U] = 2.200;
+ int22_ar[G][U][A][U][C][U][G][U] = 2.000;
+ int22_ar[G][U][A][U][G][A][G][U] = 2.300;
+ int22_ar[G][U][A][U][G][C][G][U] = 1.200;
+ int22_ar[G][U][A][U][G][G][G][U] = 1.900;
+ int22_ar[G][U][A][U][G][U][G][U] = 2.000;
+ int22_ar[G][U][A][U][U][A][G][U] = 2.700;
+ int22_ar[G][U][A][U][U][C][G][U] = 1.500;
+ int22_ar[G][U][A][U][U][G][G][U] = 2.200;
+ int22_ar[G][U][A][U][U][U][G][U] = 2.000;
+ int22_ar[G][U][C][A][A][A][G][U] = 2.500;
+ int22_ar[G][U][C][A][A][C][G][U] = 3.100;
+ int22_ar[G][U][C][A][A][G][G][U] = 2.000;
+ int22_ar[G][U][C][A][A][U][G][U] = 3.100;
+ int22_ar[G][U][C][A][C][A][G][U] = 2.300;
+ int22_ar[G][U][C][A][C][C][G][U] = 2.200;
+ int22_ar[G][U][C][A][C][G][G][U] = 2.000;
+ int22_ar[G][U][C][A][C][U][G][U] = 2.200;
+ int22_ar[G][U][C][A][G][A][G][U] = 1.300;
+ int22_ar[G][U][C][A][G][C][G][U] = 2.200;
+ int22_ar[G][U][C][A][G][G][G][U] = 2.000;
+ int22_ar[G][U][C][A][G][U][G][U] = 2.200;
+ int22_ar[G][U][C][A][U][A][G][U] = 2.000;
+ int22_ar[G][U][C][A][U][C][G][U] = 2.000;
+ int22_ar[G][U][C][A][U][G][G][U] = 2.000;
+ int22_ar[G][U][C][A][U][U][G][U] = 2.000;
+ int22_ar[G][U][C][C][A][A][G][U] = 2.400;
+ int22_ar[G][U][C][C][A][C][G][U] = 2.300;
+ int22_ar[G][U][C][C][A][G][G][U] = 2.000;
+ int22_ar[G][U][C][C][A][U][G][U] = 2.300;
+ int22_ar[G][U][C][C][C][A][G][U] = 2.200;
+ int22_ar[G][U][C][C][C][C][G][U] = 2.200;
+ int22_ar[G][U][C][C][C][G][G][U] = 2.000;
+ int22_ar[G][U][C][C][C][U][G][U] = 2.200;
+ int22_ar[G][U][C][C][G][A][G][U] = 2.000;
+ int22_ar[G][U][C][C][G][C][G][U] = 2.000;
+ int22_ar[G][U][C][C][G][G][G][U] = 2.000;
+ int22_ar[G][U][C][C][G][U][G][U] = 2.000;
+ int22_ar[G][U][C][C][U][A][G][U] = 2.200;
+ int22_ar[G][U][C][C][U][C][G][U] = 2.200;
+ int22_ar[G][U][C][C][U][G][G][U] = 2.000;
+ int22_ar[G][U][C][C][U][U][G][U] = 2.200;
+ int22_ar[G][U][C][G][A][A][G][U] = 1.300;
+ int22_ar[G][U][C][G][A][C][G][U] = 2.200;
+ int22_ar[G][U][C][G][A][G][G][U] = 2.000;
+ int22_ar[G][U][C][G][A][U][G][U] = 2.200;
+ int22_ar[G][U][C][G][C][A][G][U] = 2.000;
+ int22_ar[G][U][C][G][C][C][G][U] = 2.000;
+ int22_ar[G][U][C][G][C][G][G][U] = 2.000;
+ int22_ar[G][U][C][G][C][U][G][U] = 2.000;
+ int22_ar[G][U][C][G][G][A][G][U] = 1.800;
+ int22_ar[G][U][C][G][G][C][G][U] = 2.400;
+ int22_ar[G][U][C][G][G][G][G][U] = 2.000;
+ int22_ar[G][U][C][G][G][U][G][U] = 2.400;
+ int22_ar[G][U][C][G][U][A][G][U] = 0.100;
+ int22_ar[G][U][C][G][U][C][G][U] = 1.000;
+ int22_ar[G][U][C][G][U][G][G][U] = 2.000;
+ int22_ar[G][U][C][G][U][U][G][U] = 1.000;
+ int22_ar[G][U][C][U][A][A][G][U] = 2.000;
+ int22_ar[G][U][C][U][A][C][G][U] = 2.000;
+ int22_ar[G][U][C][U][A][G][G][U] = 2.000;
+ int22_ar[G][U][C][U][A][U][G][U] = 2.000;
+ int22_ar[G][U][C][U][C][A][G][U] = 2.200;
+ int22_ar[G][U][C][U][C][C][G][U] = 2.200;
+ int22_ar[G][U][C][U][C][G][G][U] = 2.000;
+ int22_ar[G][U][C][U][C][U][G][U] = 2.200;
+ int22_ar[G][U][C][U][G][A][G][U] = 1.100;
+ int22_ar[G][U][C][U][G][C][G][U] = 2.000;
+ int22_ar[G][U][C][U][G][G][G][U] = 2.000;
+ int22_ar[G][U][C][U][G][U][G][U] = 2.000;
+ int22_ar[G][U][C][U][U][A][G][U] = 1.400;
+ int22_ar[G][U][C][U][U][C][G][U] = 1.400;
+ int22_ar[G][U][C][U][U][G][G][U] = 2.000;
+ int22_ar[G][U][C][U][U][U][G][U] = 1.400;
+ int22_ar[G][U][G][A][A][A][G][U] = 1.500;
+ int22_ar[G][U][G][A][A][C][G][U] = 2.000;
+ int22_ar[G][U][G][A][A][G][G][U] = 2.100;
+ int22_ar[G][U][G][A][A][U][G][U] = 2.300;
+ int22_ar[G][U][G][A][C][A][G][U] = 1.300;
+ int22_ar[G][U][G][A][C][C][G][U] = 2.000;
+ int22_ar[G][U][G][A][C][G][G][U] = 1.800;
+ int22_ar[G][U][G][A][C][U][G][U] = 1.100;
+ int22_ar[G][U][G][A][G][A][G][U] = 0.300;
+ int22_ar[G][U][G][A][G][C][G][U] = 2.000;
+ int22_ar[G][U][G][A][G][G][G][U] = 0.800;
+ int22_ar[G][U][G][A][G][U][G][U] = 1.900;
+ int22_ar[G][U][G][A][U][A][G][U] = 2.000;
+ int22_ar[G][U][G][A][U][C][G][U] = 2.000;
+ int22_ar[G][U][G][A][U][G][G][U] = 2.000;
+ int22_ar[G][U][G][A][U][U][G][U] = 2.000;
+ int22_ar[G][U][G][C][A][A][G][U] = 1.400;
+ int22_ar[G][U][G][C][A][C][G][U] = 2.000;
+ int22_ar[G][U][G][C][A][G][G][U] = 1.900;
+ int22_ar[G][U][G][C][A][U][G][U] = 1.200;
+ int22_ar[G][U][G][C][C][A][G][U] = 2.200;
+ int22_ar[G][U][G][C][C][C][G][U] = 2.000;
+ int22_ar[G][U][G][C][C][G][G][U] = 2.400;
+ int22_ar[G][U][G][C][C][U][G][U] = 2.000;
+ int22_ar[G][U][G][C][G][A][G][U] = 2.000;
+ int22_ar[G][U][G][C][G][C][G][U] = 2.000;
+ int22_ar[G][U][G][C][G][G][G][U] = 2.000;
+ int22_ar[G][U][G][C][G][U][G][U] = 2.000;
+ int22_ar[G][U][G][C][U][A][G][U] = 2.200;
+ int22_ar[G][U][G][C][U][C][G][U] = 2.000;
+ int22_ar[G][U][G][C][U][G][G][U] = 2.400;
+ int22_ar[G][U][G][C][U][U][G][U] = 2.000;
+ int22_ar[G][U][G][G][A][A][G][U] = 0.300;
+ int22_ar[G][U][G][G][A][C][G][U] = 2.000;
+ int22_ar[G][U][G][G][A][G][G][U] = 0.800;
+ int22_ar[G][U][G][G][A][U][G][U] = 1.900;
+ int22_ar[G][U][G][G][C][A][G][U] = 2.000;
+ int22_ar[G][U][G][G][C][C][G][U] = 2.000;
+ int22_ar[G][U][G][G][C][G][G][U] = 2.000;
+ int22_ar[G][U][G][G][C][U][G][U] = 2.000;
+ int22_ar[G][U][G][G][G][A][G][U] = 0.800;
+ int22_ar[G][U][G][G][G][C][G][U] = 2.000;
+ int22_ar[G][U][G][G][G][G][G][U] = 1.400;
+ int22_ar[G][U][G][G][G][U][G][U] = 1.600;
+ int22_ar[G][U][G][G][U][A][G][U] = 0.900;
+ int22_ar[G][U][G][G][U][C][G][U] = 2.000;
+ int22_ar[G][U][G][G][U][G][G][U] = 0.700;
+ int22_ar[G][U][G][G][U][U][G][U] = -1.100;
+ int22_ar[G][U][G][U][A][A][G][U] = 2.000;
+ int22_ar[G][U][G][U][A][C][G][U] = 2.000;
+ int22_ar[G][U][G][U][A][G][G][U] = 2.000;
+ int22_ar[G][U][G][U][A][U][G][U] = 2.000;
+ int22_ar[G][U][G][U][C][A][G][U] = 2.200;
+ int22_ar[G][U][G][U][C][C][G][U] = 2.000;
+ int22_ar[G][U][G][U][C][G][G][U] = 2.400;
+ int22_ar[G][U][G][U][C][U][G][U] = 2.000;
+ int22_ar[G][U][G][U][G][A][G][U] = 1.900;
+ int22_ar[G][U][G][U][G][C][G][U] = 2.000;
+ int22_ar[G][U][G][U][G][G][G][U] = 1.600;
+ int22_ar[G][U][G][U][G][U][G][U] = -0.100;
+ int22_ar[G][U][G][U][U][A][G][U] = 2.200;
+ int22_ar[G][U][G][U][U][C][G][U] = 2.000;
+ int22_ar[G][U][G][U][U][G][G][U] = 2.000;
+ int22_ar[G][U][G][U][U][U][G][U] = 2.000;
+ int22_ar[G][U][U][A][A][A][G][U] = 2.000;
+ int22_ar[G][U][U][A][A][C][G][U] = 3.100;
+ int22_ar[G][U][U][A][A][G][G][U] = 1.300;
+ int22_ar[G][U][U][A][A][U][G][U] = 2.700;
+ int22_ar[G][U][U][A][C][A][G][U] = 2.000;
+ int22_ar[G][U][U][A][C][C][G][U] = 2.200;
+ int22_ar[G][U][U][A][C][G][G][U] = 0.100;
+ int22_ar[G][U][U][A][C][U][G][U] = 1.400;
+ int22_ar[G][U][U][A][G][A][G][U] = 2.000;
+ int22_ar[G][U][U][A][G][C][G][U] = 2.200;
+ int22_ar[G][U][U][A][G][G][G][U] = 0.900;
+ int22_ar[G][U][U][A][G][U][G][U] = 2.200;
+ int22_ar[G][U][U][A][U][A][G][U] = 2.000;
+ int22_ar[G][U][U][A][U][C][G][U] = 2.000;
+ int22_ar[G][U][U][A][U][G][G][U] = 2.000;
+ int22_ar[G][U][U][A][U][U][G][U] = 2.000;
+ int22_ar[G][U][U][C][A][A][G][U] = 2.000;
+ int22_ar[G][U][U][C][A][C][G][U] = 2.300;
+ int22_ar[G][U][U][C][A][G][G][U] = 0.200;
+ int22_ar[G][U][U][C][A][U][G][U] = 1.500;
+ int22_ar[G][U][U][C][C][A][G][U] = 2.000;
+ int22_ar[G][U][U][C][C][C][G][U] = 2.200;
+ int22_ar[G][U][U][C][C][G][G][U] = 1.000;
+ int22_ar[G][U][U][C][C][U][G][U] = 1.400;
+ int22_ar[G][U][U][C][G][A][G][U] = 2.000;
+ int22_ar[G][U][U][C][G][C][G][U] = 2.000;
+ int22_ar[G][U][U][C][G][G][G][U] = 2.000;
+ int22_ar[G][U][U][C][G][U][G][U] = 2.000;
+ int22_ar[G][U][U][C][U][A][G][U] = 2.000;
+ int22_ar[G][U][U][C][U][C][G][U] = 2.200;
+ int22_ar[G][U][U][C][U][G][G][U] = 1.000;
+ int22_ar[G][U][U][C][U][U][G][U] = 1.400;
+ int22_ar[G][U][U][G][A][A][G][U] = 2.000;
+ int22_ar[G][U][U][G][A][C][G][U] = 2.200;
+ int22_ar[G][U][U][G][A][G][G][U] = 0.900;
+ int22_ar[G][U][U][G][A][U][G][U] = 2.200;
+ int22_ar[G][U][U][G][C][A][G][U] = 2.000;
+ int22_ar[G][U][U][G][C][C][G][U] = 2.000;
+ int22_ar[G][U][U][G][C][G][G][U] = 2.000;
+ int22_ar[G][U][U][G][C][U][G][U] = 2.000;
+ int22_ar[G][U][U][G][G][A][G][U] = 2.000;
+ int22_ar[G][U][U][G][G][C][G][U] = 2.400;
+ int22_ar[G][U][U][G][G][G][G][U] = 0.700;
+ int22_ar[G][U][U][G][G][U][G][U] = 2.000;
+ int22_ar[G][U][U][G][U][A][G][U] = 2.000;
+ int22_ar[G][U][U][G][U][C][G][U] = 1.000;
+ int22_ar[G][U][U][G][U][G][G][U] = -2.100;
+ int22_ar[G][U][U][G][U][U][G][U] = 1.100;
+ int22_ar[G][U][U][U][A][A][G][U] = 2.000;
+ int22_ar[G][U][U][U][A][C][G][U] = 2.000;
+ int22_ar[G][U][U][U][A][G][G][U] = 2.000;
+ int22_ar[G][U][U][U][A][U][G][U] = 2.000;
+ int22_ar[G][U][U][U][C][A][G][U] = 2.000;
+ int22_ar[G][U][U][U][C][C][G][U] = 2.200;
+ int22_ar[G][U][U][U][C][G][G][U] = 1.000;
+ int22_ar[G][U][U][U][C][U][G][U] = 1.400;
+ int22_ar[G][U][U][U][G][A][G][U] = 2.000;
+ int22_ar[G][U][U][U][G][C][G][U] = 2.000;
+ int22_ar[G][U][U][U][G][G][G][U] = -1.100;
+ int22_ar[G][U][U][U][G][U][G][U] = 2.000;
+ int22_ar[G][U][U][U][U][A][G][U] = 2.000;
+ int22_ar[G][U][U][U][U][C][G][U] = 1.400;
+ int22_ar[G][U][U][U][U][G][G][U] = 1.100;
+ int22_ar[G][U][U][U][U][U][G][U] = 0.600;
+ int22_ar[G][U][A][A][A][A][U][A] = 2.800;
+ int22_ar[G][U][A][A][A][C][U][A] = 2.600;
+ int22_ar[G][U][A][A][A][G][U][A] = 1.500;
+ int22_ar[G][U][A][A][A][U][U][A] = 2.000;
+ int22_ar[G][U][A][A][C][A][U][A] = 2.300;
+ int22_ar[G][U][A][A][C][C][U][A] = 2.200;
+ int22_ar[G][U][A][A][C][G][U][A] = 1.100;
+ int22_ar[G][U][A][A][C][U][U][A] = 2.000;
+ int22_ar[G][U][A][A][G][A][U][A] = 1.700;
+ int22_ar[G][U][A][A][G][C][U][A] = 1.600;
+ int22_ar[G][U][A][A][G][G][U][A] = 0.500;
+ int22_ar[G][U][A][A][G][U][U][A] = 2.000;
+ int22_ar[G][U][A][A][U][A][U][A] = 2.000;
+ int22_ar[G][U][A][A][U][C][U][A] = 2.000;
+ int22_ar[G][U][A][A][U][G][U][A] = 2.000;
+ int22_ar[G][U][A][A][U][U][U][A] = 2.000;
+ int22_ar[G][U][A][C][A][A][U][A] = 2.800;
+ int22_ar[G][U][A][C][A][C][U][A] = 2.600;
+ int22_ar[G][U][A][C][A][G][U][A] = 1.500;
+ int22_ar[G][U][A][C][A][U][U][A] = 2.000;
+ int22_ar[G][U][A][C][C][A][U][A] = 3.400;
+ int22_ar[G][U][A][C][C][C][U][A] = 2.600;
+ int22_ar[G][U][A][C][C][G][U][A] = 2.500;
+ int22_ar[G][U][A][C][C][U][U][A] = 2.000;
+ int22_ar[G][U][A][C][G][A][U][A] = 2.000;
+ int22_ar[G][U][A][C][G][C][U][A] = 2.000;
+ int22_ar[G][U][A][C][G][G][U][A] = 2.000;
+ int22_ar[G][U][A][C][G][U][U][A] = 2.000;
+ int22_ar[G][U][A][C][U][A][U][A] = 3.400;
+ int22_ar[G][U][A][C][U][C][U][A] = 2.600;
+ int22_ar[G][U][A][C][U][G][U][A] = 2.500;
+ int22_ar[G][U][A][C][U][U][U][A] = 2.000;
+ int22_ar[G][U][A][G][A][A][U][A] = 1.700;
+ int22_ar[G][U][A][G][A][C][U][A] = 1.600;
+ int22_ar[G][U][A][G][A][G][U][A] = 0.500;
+ int22_ar[G][U][A][G][A][U][U][A] = 2.000;
+ int22_ar[G][U][A][G][C][A][U][A] = 2.000;
+ int22_ar[G][U][A][G][C][C][U][A] = 2.000;
+ int22_ar[G][U][A][G][C][G][U][A] = 2.000;
+ int22_ar[G][U][A][G][C][U][U][A] = 2.000;
+ int22_ar[G][U][A][G][G][A][U][A] = 2.100;
+ int22_ar[G][U][A][G][G][C][U][A] = 2.000;
+ int22_ar[G][U][A][G][G][G][U][A] = 0.900;
+ int22_ar[G][U][A][G][G][U][U][A] = 2.000;
+ int22_ar[G][U][A][G][U][A][U][A] = 1.000;
+ int22_ar[G][U][A][G][U][C][U][A] = -0.200;
+ int22_ar[G][U][A][G][U][G][U][A] = 0.500;
+ int22_ar[G][U][A][G][U][U][U][A] = 2.000;
+ int22_ar[G][U][A][U][A][A][U][A] = 2.000;
+ int22_ar[G][U][A][U][A][C][U][A] = 2.000;
+ int22_ar[G][U][A][U][A][G][U][A] = 2.000;
+ int22_ar[G][U][A][U][A][U][U][A] = 2.000;
+ int22_ar[G][U][A][U][C][A][U][A] = 3.100;
+ int22_ar[G][U][A][U][C][C][U][A] = 2.300;
+ int22_ar[G][U][A][U][C][G][U][A] = 2.200;
+ int22_ar[G][U][A][U][C][U][U][A] = 2.000;
+ int22_ar[G][U][A][U][G][A][U][A] = 2.200;
+ int22_ar[G][U][A][U][G][C][U][A] = 1.100;
+ int22_ar[G][U][A][U][G][G][U][A] = 1.800;
+ int22_ar[G][U][A][U][G][U][U][A] = 2.000;
+ int22_ar[G][U][A][U][U][A][U][A] = 2.900;
+ int22_ar[G][U][A][U][U][C][U][A] = 1.800;
+ int22_ar[G][U][A][U][U][G][U][A] = 2.500;
+ int22_ar[G][U][A][U][U][U][U][A] = 2.000;
+ int22_ar[G][U][C][A][A][A][U][A] = 2.500;
+ int22_ar[G][U][C][A][A][C][U][A] = 3.100;
+ int22_ar[G][U][C][A][A][G][U][A] = 2.000;
+ int22_ar[G][U][C][A][A][U][U][A] = 3.100;
+ int22_ar[G][U][C][A][C][A][U][A] = 2.100;
+ int22_ar[G][U][C][A][C][C][U][A] = 2.000;
+ int22_ar[G][U][C][A][C][G][U][A] = 2.000;
+ int22_ar[G][U][C][A][C][U][U][A] = 2.000;
+ int22_ar[G][U][C][A][G][A][U][A] = 1.500;
+ int22_ar[G][U][C][A][G][C][U][A] = 2.400;
+ int22_ar[G][U][C][A][G][G][U][A] = 2.000;
+ int22_ar[G][U][C][A][G][U][U][A] = 2.400;
+ int22_ar[G][U][C][A][U][A][U][A] = 2.000;
+ int22_ar[G][U][C][A][U][C][U][A] = 2.000;
+ int22_ar[G][U][C][A][U][G][U][A] = 2.000;
+ int22_ar[G][U][C][A][U][U][U][A] = 2.000;
+ int22_ar[G][U][C][C][A][A][U][A] = 2.500;
+ int22_ar[G][U][C][C][A][C][U][A] = 2.500;
+ int22_ar[G][U][C][C][A][G][U][A] = 2.000;
+ int22_ar[G][U][C][C][A][U][U][A] = 2.500;
+ int22_ar[G][U][C][C][C][A][U][A] = 2.500;
+ int22_ar[G][U][C][C][C][C][U][A] = 2.500;
+ int22_ar[G][U][C][C][C][G][U][A] = 2.000;
+ int22_ar[G][U][C][C][C][U][U][A] = 2.500;
+ int22_ar[G][U][C][C][G][A][U][A] = 2.000;
+ int22_ar[G][U][C][C][G][C][U][A] = 2.000;
+ int22_ar[G][U][C][C][G][G][U][A] = 2.000;
+ int22_ar[G][U][C][C][G][U][U][A] = 2.000;
+ int22_ar[G][U][C][C][U][A][U][A] = 2.500;
+ int22_ar[G][U][C][C][U][C][U][A] = 2.500;
+ int22_ar[G][U][C][C][U][G][U][A] = 2.000;
+ int22_ar[G][U][C][C][U][U][U][A] = 2.500;
+ int22_ar[G][U][C][G][A][A][U][A] = 1.500;
+ int22_ar[G][U][C][G][A][C][U][A] = 2.400;
+ int22_ar[G][U][C][G][A][G][U][A] = 2.000;
+ int22_ar[G][U][C][G][A][U][U][A] = 2.400;
+ int22_ar[G][U][C][G][C][A][U][A] = 2.000;
+ int22_ar[G][U][C][G][C][C][U][A] = 2.000;
+ int22_ar[G][U][C][G][C][G][U][A] = 2.000;
+ int22_ar[G][U][C][G][C][U][U][A] = 2.000;
+ int22_ar[G][U][C][G][G][A][U][A] = 1.900;
+ int22_ar[G][U][C][G][G][C][U][A] = 2.400;
+ int22_ar[G][U][C][G][G][G][U][A] = 2.000;
+ int22_ar[G][U][C][G][G][U][U][A] = 2.400;
+ int22_ar[G][U][C][G][U][A][U][A] = -0.300;
+ int22_ar[G][U][C][G][U][C][U][A] = 0.700;
+ int22_ar[G][U][C][G][U][G][U][A] = 2.000;
+ int22_ar[G][U][C][G][U][U][U][A] = 0.700;
+ int22_ar[G][U][C][U][A][A][U][A] = 2.000;
+ int22_ar[G][U][C][U][A][C][U][A] = 2.000;
+ int22_ar[G][U][C][U][A][G][U][A] = 2.000;
+ int22_ar[G][U][C][U][A][U][U][A] = 2.000;
+ int22_ar[G][U][C][U][C][A][U][A] = 2.200;
+ int22_ar[G][U][C][U][C][C][U][A] = 2.200;
+ int22_ar[G][U][C][U][C][G][U][A] = 2.000;
+ int22_ar[G][U][C][U][C][U][U][A] = 2.200;
+ int22_ar[G][U][C][U][G][A][U][A] = 1.000;
+ int22_ar[G][U][C][U][G][C][U][A] = 1.900;
+ int22_ar[G][U][C][U][G][G][U][A] = 2.000;
+ int22_ar[G][U][C][U][G][U][U][A] = 1.900;
+ int22_ar[G][U][C][U][U][A][U][A] = 1.700;
+ int22_ar[G][U][C][U][U][C][U][A] = 1.600;
+ int22_ar[G][U][C][U][U][G][U][A] = 2.000;
+ int22_ar[G][U][C][U][U][U][U][A] = 1.600;
+ int22_ar[G][U][G][A][A][A][U][A] = 1.500;
+ int22_ar[G][U][G][A][A][C][U][A] = 2.000;
+ int22_ar[G][U][G][A][A][G][U][A] = 2.100;
+ int22_ar[G][U][G][A][A][U][U][A] = 2.300;
+ int22_ar[G][U][G][A][C][A][U][A] = 1.100;
+ int22_ar[G][U][G][A][C][C][U][A] = 2.000;
+ int22_ar[G][U][G][A][C][G][U][A] = 1.600;
+ int22_ar[G][U][G][A][C][U][U][A] = 0.900;
+ int22_ar[G][U][G][A][G][A][U][A] = 0.500;
+ int22_ar[G][U][G][A][G][C][U][A] = 2.000;
+ int22_ar[G][U][G][A][G][G][U][A] = 1.000;
+ int22_ar[G][U][G][A][G][U][U][A] = 2.100;
+ int22_ar[G][U][G][A][U][A][U][A] = 2.000;
+ int22_ar[G][U][G][A][U][C][U][A] = 2.000;
+ int22_ar[G][U][G][A][U][G][U][A] = 2.000;
+ int22_ar[G][U][G][A][U][U][U][A] = 2.000;
+ int22_ar[G][U][G][C][A][A][U][A] = 1.500;
+ int22_ar[G][U][G][C][A][C][U][A] = 2.000;
+ int22_ar[G][U][G][C][A][G][U][A] = 2.100;
+ int22_ar[G][U][G][C][A][U][U][A] = 1.300;
+ int22_ar[G][U][G][C][C][A][U][A] = 2.500;
+ int22_ar[G][U][G][C][C][C][U][A] = 2.000;
+ int22_ar[G][U][G][C][C][G][U][A] = 2.700;
+ int22_ar[G][U][G][C][C][U][U][A] = 2.300;
+ int22_ar[G][U][G][C][G][A][U][A] = 2.000;
+ int22_ar[G][U][G][C][G][C][U][A] = 2.000;
+ int22_ar[G][U][G][C][G][G][U][A] = 2.000;
+ int22_ar[G][U][G][C][G][U][U][A] = 2.000;
+ int22_ar[G][U][G][C][U][A][U][A] = 2.500;
+ int22_ar[G][U][G][C][U][C][U][A] = 2.000;
+ int22_ar[G][U][G][C][U][G][U][A] = 2.700;
+ int22_ar[G][U][G][C][U][U][U][A] = 2.300;
+ int22_ar[G][U][G][G][A][A][U][A] = 0.500;
+ int22_ar[G][U][G][G][A][C][U][A] = 2.000;
+ int22_ar[G][U][G][G][A][G][U][A] = 1.000;
+ int22_ar[G][U][G][G][A][U][U][A] = 2.100;
+ int22_ar[G][U][G][G][C][A][U][A] = 2.000;
+ int22_ar[G][U][G][G][C][C][U][A] = 2.000;
+ int22_ar[G][U][G][G][C][G][U][A] = 2.000;
+ int22_ar[G][U][G][G][C][U][U][A] = 2.000;
+ int22_ar[G][U][G][G][G][A][U][A] = 0.900;
+ int22_ar[G][U][G][G][G][C][U][A] = 2.000;
+ int22_ar[G][U][G][G][G][G][U][A] = 1.400;
+ int22_ar[G][U][G][G][G][U][U][A] = 1.700;
+ int22_ar[G][U][G][G][U][A][U][A] = 0.500;
+ int22_ar[G][U][G][G][U][C][U][A] = 2.000;
+ int22_ar[G][U][G][G][U][G][U][A] = 0.300;
+ int22_ar[G][U][G][G][U][U][U][A] = -1.500;
+ int22_ar[G][U][G][U][A][A][U][A] = 2.000;
+ int22_ar[G][U][G][U][A][C][U][A] = 2.000;
+ int22_ar[G][U][G][U][A][G][U][A] = 2.000;
+ int22_ar[G][U][G][U][A][U][U][A] = 2.000;
+ int22_ar[G][U][G][U][C][A][U][A] = 2.200;
+ int22_ar[G][U][G][U][C][C][U][A] = 2.000;
+ int22_ar[G][U][G][U][C][G][U][A] = 2.400;
+ int22_ar[G][U][G][U][C][U][U][A] = 2.000;
+ int22_ar[G][U][G][U][G][A][U][A] = 1.800;
+ int22_ar[G][U][G][U][G][C][U][A] = 2.000;
+ int22_ar[G][U][G][U][G][G][U][A] = 1.500;
+ int22_ar[G][U][G][U][G][U][U][A] = -0.200;
+ int22_ar[G][U][G][U][U][A][U][A] = 2.500;
+ int22_ar[G][U][G][U][U][C][U][A] = 2.000;
+ int22_ar[G][U][G][U][U][G][U][A] = 2.200;
+ int22_ar[G][U][G][U][U][U][U][A] = 2.300;
+ int22_ar[G][U][U][A][A][A][U][A] = 2.000;
+ int22_ar[G][U][U][A][A][C][U][A] = 3.100;
+ int22_ar[G][U][U][A][A][G][U][A] = 1.300;
+ int22_ar[G][U][U][A][A][U][U][A] = 2.700;
+ int22_ar[G][U][U][A][C][A][U][A] = 2.000;
+ int22_ar[G][U][U][A][C][C][U][A] = 2.000;
+ int22_ar[G][U][U][A][C][G][U][A] = -0.100;
+ int22_ar[G][U][U][A][C][U][U][A] = 1.200;
+ int22_ar[G][U][U][A][G][A][U][A] = 2.000;
+ int22_ar[G][U][U][A][G][C][U][A] = 2.400;
+ int22_ar[G][U][U][A][G][G][U][A] = 1.100;
+ int22_ar[G][U][U][A][G][U][U][A] = 2.400;
+ int22_ar[G][U][U][A][U][A][U][A] = 2.000;
+ int22_ar[G][U][U][A][U][C][U][A] = 2.000;
+ int22_ar[G][U][U][A][U][G][U][A] = 2.000;
+ int22_ar[G][U][U][A][U][U][U][A] = 2.000;
+ int22_ar[G][U][U][C][A][A][U][A] = 2.000;
+ int22_ar[G][U][U][C][A][C][U][A] = 2.500;
+ int22_ar[G][U][U][C][A][G][U][A] = 0.300;
+ int22_ar[G][U][U][C][A][U][U][A] = 1.700;
+ int22_ar[G][U][U][C][C][A][U][A] = 2.000;
+ int22_ar[G][U][U][C][C][C][U][A] = 2.500;
+ int22_ar[G][U][U][C][C][G][U][A] = 1.300;
+ int22_ar[G][U][U][C][C][U][U][A] = 1.700;
+ int22_ar[G][U][U][C][G][A][U][A] = 2.000;
+ int22_ar[G][U][U][C][G][C][U][A] = 2.000;
+ int22_ar[G][U][U][C][G][G][U][A] = 2.000;
+ int22_ar[G][U][U][C][G][U][U][A] = 2.000;
+ int22_ar[G][U][U][C][U][A][U][A] = 2.000;
+ int22_ar[G][U][U][C][U][C][U][A] = 2.500;
+ int22_ar[G][U][U][C][U][G][U][A] = 1.300;
+ int22_ar[G][U][U][C][U][U][U][A] = 1.700;
+ int22_ar[G][U][U][G][A][A][U][A] = 2.000;
+ int22_ar[G][U][U][G][A][C][U][A] = 2.400;
+ int22_ar[G][U][U][G][A][G][U][A] = 1.100;
+ int22_ar[G][U][U][G][A][U][U][A] = 2.400;
+ int22_ar[G][U][U][G][C][A][U][A] = 2.000;
+ int22_ar[G][U][U][G][C][C][U][A] = 2.000;
+ int22_ar[G][U][U][G][C][G][U][A] = 2.000;
+ int22_ar[G][U][U][G][C][U][U][A] = 2.000;
+ int22_ar[G][U][U][G][G][A][U][A] = 2.000;
+ int22_ar[G][U][U][G][G][C][U][A] = 2.400;
+ int22_ar[G][U][U][G][G][G][U][A] = 0.700;
+ int22_ar[G][U][U][G][G][U][U][A] = 2.000;
+ int22_ar[G][U][U][G][U][A][U][A] = 2.000;
+ int22_ar[G][U][U][G][U][C][U][A] = 0.700;
+ int22_ar[G][U][U][G][U][G][U][A] = -2.500;
+ int22_ar[G][U][U][G][U][U][U][A] = 0.700;
+ int22_ar[G][U][U][U][A][A][U][A] = 2.000;
+ int22_ar[G][U][U][U][A][C][U][A] = 2.000;
+ int22_ar[G][U][U][U][A][G][U][A] = 2.000;
+ int22_ar[G][U][U][U][A][U][U][A] = 2.000;
+ int22_ar[G][U][U][U][C][A][U][A] = 2.000;
+ int22_ar[G][U][U][U][C][C][U][A] = 2.200;
+ int22_ar[G][U][U][U][C][G][U][A] = 1.000;
+ int22_ar[G][U][U][U][C][U][U][A] = 1.400;
+ int22_ar[G][U][U][U][G][A][U][A] = 2.000;
+ int22_ar[G][U][U][U][G][C][U][A] = 1.900;
+ int22_ar[G][U][U][U][G][G][U][A] = -1.200;
+ int22_ar[G][U][U][U][G][U][U][A] = 1.900;
+ int22_ar[G][U][U][U][U][A][U][A] = 2.000;
+ int22_ar[G][U][U][U][U][C][U][A] = 1.600;
+ int22_ar[G][U][U][U][U][G][U][A] = 1.300;
+ int22_ar[G][U][U][U][U][U][U][A] = 0.800;
+ int22_ar[G][U][A][A][A][A][U][G] = 2.800;
+ int22_ar[G][U][A][A][A][C][U][G] = 2.600;
+ int22_ar[G][U][A][A][A][G][U][G] = 1.500;
+ int22_ar[G][U][A][A][A][U][U][G] = 2.000;
+ int22_ar[G][U][A][A][C][A][U][G] = 2.300;
+ int22_ar[G][U][A][A][C][C][U][G] = 2.200;
+ int22_ar[G][U][A][A][C][G][U][G] = 1.100;
+ int22_ar[G][U][A][A][C][U][U][G] = 2.000;
+ int22_ar[G][U][A][A][G][A][U][G] = 1.700;
+ int22_ar[G][U][A][A][G][C][U][G] = 1.600;
+ int22_ar[G][U][A][A][G][G][U][G] = 0.500;
+ int22_ar[G][U][A][A][G][U][U][G] = 2.000;
+ int22_ar[G][U][A][A][U][A][U][G] = 2.000;
+ int22_ar[G][U][A][A][U][C][U][G] = 2.000;
+ int22_ar[G][U][A][A][U][G][U][G] = 2.000;
+ int22_ar[G][U][A][A][U][U][U][G] = 2.000;
+ int22_ar[G][U][A][C][A][A][U][G] = 2.800;
+ int22_ar[G][U][A][C][A][C][U][G] = 2.600;
+ int22_ar[G][U][A][C][A][G][U][G] = 1.500;
+ int22_ar[G][U][A][C][A][U][U][G] = 2.000;
+ int22_ar[G][U][A][C][C][A][U][G] = 3.400;
+ int22_ar[G][U][A][C][C][C][U][G] = 2.600;
+ int22_ar[G][U][A][C][C][G][U][G] = 2.500;
+ int22_ar[G][U][A][C][C][U][U][G] = 2.000;
+ int22_ar[G][U][A][C][G][A][U][G] = 2.000;
+ int22_ar[G][U][A][C][G][C][U][G] = 2.000;
+ int22_ar[G][U][A][C][G][G][U][G] = 2.000;
+ int22_ar[G][U][A][C][G][U][U][G] = 2.000;
+ int22_ar[G][U][A][C][U][A][U][G] = 3.400;
+ int22_ar[G][U][A][C][U][C][U][G] = 2.600;
+ int22_ar[G][U][A][C][U][G][U][G] = 2.500;
+ int22_ar[G][U][A][C][U][U][U][G] = 2.000;
+ int22_ar[G][U][A][G][A][A][U][G] = 1.700;
+ int22_ar[G][U][A][G][A][C][U][G] = 1.600;
+ int22_ar[G][U][A][G][A][G][U][G] = 0.500;
+ int22_ar[G][U][A][G][A][U][U][G] = 2.000;
+ int22_ar[G][U][A][G][C][A][U][G] = 2.000;
+ int22_ar[G][U][A][G][C][C][U][G] = 2.000;
+ int22_ar[G][U][A][G][C][G][U][G] = 2.000;
+ int22_ar[G][U][A][G][C][U][U][G] = 2.000;
+ int22_ar[G][U][A][G][G][A][U][G] = 2.100;
+ int22_ar[G][U][A][G][G][C][U][G] = 2.000;
+ int22_ar[G][U][A][G][G][G][U][G] = 0.900;
+ int22_ar[G][U][A][G][G][U][U][G] = 2.000;
+ int22_ar[G][U][A][G][U][A][U][G] = 1.000;
+ int22_ar[G][U][A][G][U][C][U][G] = -0.200;
+ int22_ar[G][U][A][G][U][G][U][G] = 0.500;
+ int22_ar[G][U][A][G][U][U][U][G] = 2.000;
+ int22_ar[G][U][A][U][A][A][U][G] = 2.000;
+ int22_ar[G][U][A][U][A][C][U][G] = 2.000;
+ int22_ar[G][U][A][U][A][G][U][G] = 2.000;
+ int22_ar[G][U][A][U][A][U][U][G] = 2.000;
+ int22_ar[G][U][A][U][C][A][U][G] = 3.100;
+ int22_ar[G][U][A][U][C][C][U][G] = 2.300;
+ int22_ar[G][U][A][U][C][G][U][G] = 2.200;
+ int22_ar[G][U][A][U][C][U][U][G] = 2.000;
+ int22_ar[G][U][A][U][G][A][U][G] = 2.200;
+ int22_ar[G][U][A][U][G][C][U][G] = 1.100;
+ int22_ar[G][U][A][U][G][G][U][G] = 1.800;
+ int22_ar[G][U][A][U][G][U][U][G] = 2.000;
+ int22_ar[G][U][A][U][U][A][U][G] = 2.900;
+ int22_ar[G][U][A][U][U][C][U][G] = 1.800;
+ int22_ar[G][U][A][U][U][G][U][G] = 2.500;
+ int22_ar[G][U][A][U][U][U][U][G] = 2.000;
+ int22_ar[G][U][C][A][A][A][U][G] = 2.500;
+ int22_ar[G][U][C][A][A][C][U][G] = 3.100;
+ int22_ar[G][U][C][A][A][G][U][G] = 2.000;
+ int22_ar[G][U][C][A][A][U][U][G] = 3.100;
+ int22_ar[G][U][C][A][C][A][U][G] = 2.100;
+ int22_ar[G][U][C][A][C][C][U][G] = 2.000;
+ int22_ar[G][U][C][A][C][G][U][G] = 2.000;
+ int22_ar[G][U][C][A][C][U][U][G] = 2.000;
+ int22_ar[G][U][C][A][G][A][U][G] = 1.500;
+ int22_ar[G][U][C][A][G][C][U][G] = 2.400;
+ int22_ar[G][U][C][A][G][G][U][G] = 2.000;
+ int22_ar[G][U][C][A][G][U][U][G] = 2.400;
+ int22_ar[G][U][C][A][U][A][U][G] = 2.000;
+ int22_ar[G][U][C][A][U][C][U][G] = 2.000;
+ int22_ar[G][U][C][A][U][G][U][G] = 2.000;
+ int22_ar[G][U][C][A][U][U][U][G] = 2.000;
+ int22_ar[G][U][C][C][A][A][U][G] = 2.500;
+ int22_ar[G][U][C][C][A][C][U][G] = 2.500;
+ int22_ar[G][U][C][C][A][G][U][G] = 2.000;
+ int22_ar[G][U][C][C][A][U][U][G] = 2.500;
+ int22_ar[G][U][C][C][C][A][U][G] = 2.500;
+ int22_ar[G][U][C][C][C][C][U][G] = 2.500;
+ int22_ar[G][U][C][C][C][G][U][G] = 2.000;
+ int22_ar[G][U][C][C][C][U][U][G] = 2.500;
+ int22_ar[G][U][C][C][G][A][U][G] = 2.000;
+ int22_ar[G][U][C][C][G][C][U][G] = 2.000;
+ int22_ar[G][U][C][C][G][G][U][G] = 2.000;
+ int22_ar[G][U][C][C][G][U][U][G] = 2.000;
+ int22_ar[G][U][C][C][U][A][U][G] = 2.500;
+ int22_ar[G][U][C][C][U][C][U][G] = 2.500;
+ int22_ar[G][U][C][C][U][G][U][G] = 2.000;
+ int22_ar[G][U][C][C][U][U][U][G] = 2.500;
+ int22_ar[G][U][C][G][A][A][U][G] = 1.500;
+ int22_ar[G][U][C][G][A][C][U][G] = 2.400;
+ int22_ar[G][U][C][G][A][G][U][G] = 2.000;
+ int22_ar[G][U][C][G][A][U][U][G] = 2.400;
+ int22_ar[G][U][C][G][C][A][U][G] = 2.000;
+ int22_ar[G][U][C][G][C][C][U][G] = 2.000;
+ int22_ar[G][U][C][G][C][G][U][G] = 2.000;
+ int22_ar[G][U][C][G][C][U][U][G] = 2.000;
+ int22_ar[G][U][C][G][G][A][U][G] = 1.900;
+ int22_ar[G][U][C][G][G][C][U][G] = 2.400;
+ int22_ar[G][U][C][G][G][G][U][G] = 2.000;
+ int22_ar[G][U][C][G][G][U][U][G] = 2.400;
+ int22_ar[G][U][C][G][U][A][U][G] = -0.300;
+ int22_ar[G][U][C][G][U][C][U][G] = 0.700;
+ int22_ar[G][U][C][G][U][G][U][G] = 2.000;
+ int22_ar[G][U][C][G][U][U][U][G] = 0.700;
+ int22_ar[G][U][C][U][A][A][U][G] = 2.000;
+ int22_ar[G][U][C][U][A][C][U][G] = 2.000;
+ int22_ar[G][U][C][U][A][G][U][G] = 2.000;
+ int22_ar[G][U][C][U][A][U][U][G] = 2.000;
+ int22_ar[G][U][C][U][C][A][U][G] = 2.200;
+ int22_ar[G][U][C][U][C][C][U][G] = 2.200;
+ int22_ar[G][U][C][U][C][G][U][G] = 2.000;
+ int22_ar[G][U][C][U][C][U][U][G] = 2.200;
+ int22_ar[G][U][C][U][G][A][U][G] = 1.000;
+ int22_ar[G][U][C][U][G][C][U][G] = 1.900;
+ int22_ar[G][U][C][U][G][G][U][G] = 2.000;
+ int22_ar[G][U][C][U][G][U][U][G] = 1.900;
+ int22_ar[G][U][C][U][U][A][U][G] = 1.700;
+ int22_ar[G][U][C][U][U][C][U][G] = 1.600;
+ int22_ar[G][U][C][U][U][G][U][G] = 2.000;
+ int22_ar[G][U][C][U][U][U][U][G] = 1.600;
+ int22_ar[G][U][G][A][A][A][U][G] = 1.500;
+ int22_ar[G][U][G][A][A][C][U][G] = 2.000;
+ int22_ar[G][U][G][A][A][G][U][G] = 2.100;
+ int22_ar[G][U][G][A][A][U][U][G] = 2.300;
+ int22_ar[G][U][G][A][C][A][U][G] = 1.100;
+ int22_ar[G][U][G][A][C][C][U][G] = 2.000;
+ int22_ar[G][U][G][A][C][G][U][G] = 1.600;
+ int22_ar[G][U][G][A][C][U][U][G] = 0.900;
+ int22_ar[G][U][G][A][G][A][U][G] = 0.500;
+ int22_ar[G][U][G][A][G][C][U][G] = 2.000;
+ int22_ar[G][U][G][A][G][G][U][G] = 1.000;
+ int22_ar[G][U][G][A][G][U][U][G] = 2.100;
+ int22_ar[G][U][G][A][U][A][U][G] = 2.000;
+ int22_ar[G][U][G][A][U][C][U][G] = 2.000;
+ int22_ar[G][U][G][A][U][G][U][G] = 2.000;
+ int22_ar[G][U][G][A][U][U][U][G] = 2.000;
+ int22_ar[G][U][G][C][A][A][U][G] = 1.500;
+ int22_ar[G][U][G][C][A][C][U][G] = 2.000;
+ int22_ar[G][U][G][C][A][G][U][G] = 2.100;
+ int22_ar[G][U][G][C][A][U][U][G] = 1.300;
+ int22_ar[G][U][G][C][C][A][U][G] = 2.500;
+ int22_ar[G][U][G][C][C][C][U][G] = 2.000;
+ int22_ar[G][U][G][C][C][G][U][G] = 2.700;
+ int22_ar[G][U][G][C][C][U][U][G] = 2.300;
+ int22_ar[G][U][G][C][G][A][U][G] = 2.000;
+ int22_ar[G][U][G][C][G][C][U][G] = 2.000;
+ int22_ar[G][U][G][C][G][G][U][G] = 2.000;
+ int22_ar[G][U][G][C][G][U][U][G] = 2.000;
+ int22_ar[G][U][G][C][U][A][U][G] = 2.500;
+ int22_ar[G][U][G][C][U][C][U][G] = 2.000;
+ int22_ar[G][U][G][C][U][G][U][G] = 2.700;
+ int22_ar[G][U][G][C][U][U][U][G] = 2.300;
+ int22_ar[G][U][G][G][A][A][U][G] = 0.500;
+ int22_ar[G][U][G][G][A][C][U][G] = 2.000;
+ int22_ar[G][U][G][G][A][G][U][G] = 1.000;
+ int22_ar[G][U][G][G][A][U][U][G] = 2.100;
+ int22_ar[G][U][G][G][C][A][U][G] = 2.000;
+ int22_ar[G][U][G][G][C][C][U][G] = 2.000;
+ int22_ar[G][U][G][G][C][G][U][G] = 2.000;
+ int22_ar[G][U][G][G][C][U][U][G] = 2.000;
+ int22_ar[G][U][G][G][G][A][U][G] = 0.900;
+ int22_ar[G][U][G][G][G][C][U][G] = 2.000;
+ int22_ar[G][U][G][G][G][G][U][G] = 1.400;
+ int22_ar[G][U][G][G][G][U][U][G] = 1.700;
+ int22_ar[G][U][G][G][U][A][U][G] = 0.500;
+ int22_ar[G][U][G][G][U][C][U][G] = 2.000;
+ int22_ar[G][U][G][G][U][G][U][G] = 0.300;
+ int22_ar[G][U][G][G][U][U][U][G] = -1.500;
+ int22_ar[G][U][G][U][A][A][U][G] = 2.000;
+ int22_ar[G][U][G][U][A][C][U][G] = 2.000;
+ int22_ar[G][U][G][U][A][G][U][G] = 2.000;
+ int22_ar[G][U][G][U][A][U][U][G] = 2.000;
+ int22_ar[G][U][G][U][C][A][U][G] = 2.200;
+ int22_ar[G][U][G][U][C][C][U][G] = 2.000;
+ int22_ar[G][U][G][U][C][G][U][G] = 2.400;
+ int22_ar[G][U][G][U][C][U][U][G] = 2.000;
+ int22_ar[G][U][G][U][G][A][U][G] = 1.800;
+ int22_ar[G][U][G][U][G][C][U][G] = 2.000;
+ int22_ar[G][U][G][U][G][G][U][G] = 1.500;
+ int22_ar[G][U][G][U][G][U][U][G] = -0.200;
+ int22_ar[G][U][G][U][U][A][U][G] = 2.500;
+ int22_ar[G][U][G][U][U][C][U][G] = 2.000;
+ int22_ar[G][U][G][U][U][G][U][G] = 2.200;
+ int22_ar[G][U][G][U][U][U][U][G] = 2.300;
+ int22_ar[G][U][U][A][A][A][U][G] = 2.000;
+ int22_ar[G][U][U][A][A][C][U][G] = 3.100;
+ int22_ar[G][U][U][A][A][G][U][G] = 1.300;
+ int22_ar[G][U][U][A][A][U][U][G] = 2.700;
+ int22_ar[G][U][U][A][C][A][U][G] = 2.000;
+ int22_ar[G][U][U][A][C][C][U][G] = 2.000;
+ int22_ar[G][U][U][A][C][G][U][G] = -0.100;
+ int22_ar[G][U][U][A][C][U][U][G] = 1.200;
+ int22_ar[G][U][U][A][G][A][U][G] = 2.000;
+ int22_ar[G][U][U][A][G][C][U][G] = 2.400;
+ int22_ar[G][U][U][A][G][G][U][G] = 1.100;
+ int22_ar[G][U][U][A][G][U][U][G] = 2.400;
+ int22_ar[G][U][U][A][U][A][U][G] = 2.000;
+ int22_ar[G][U][U][A][U][C][U][G] = 2.000;
+ int22_ar[G][U][U][A][U][G][U][G] = 2.000;
+ int22_ar[G][U][U][A][U][U][U][G] = 2.000;
+ int22_ar[G][U][U][C][A][A][U][G] = 2.000;
+ int22_ar[G][U][U][C][A][C][U][G] = 2.500;
+ int22_ar[G][U][U][C][A][G][U][G] = 0.300;
+ int22_ar[G][U][U][C][A][U][U][G] = 1.700;
+ int22_ar[G][U][U][C][C][A][U][G] = 2.000;
+ int22_ar[G][U][U][C][C][C][U][G] = 2.500;
+ int22_ar[G][U][U][C][C][G][U][G] = 1.300;
+ int22_ar[G][U][U][C][C][U][U][G] = 1.700;
+ int22_ar[G][U][U][C][G][A][U][G] = 2.000;
+ int22_ar[G][U][U][C][G][C][U][G] = 2.000;
+ int22_ar[G][U][U][C][G][G][U][G] = 2.000;
+ int22_ar[G][U][U][C][G][U][U][G] = 2.000;
+ int22_ar[G][U][U][C][U][A][U][G] = 2.000;
+ int22_ar[G][U][U][C][U][C][U][G] = 2.500;
+ int22_ar[G][U][U][C][U][G][U][G] = 1.300;
+ int22_ar[G][U][U][C][U][U][U][G] = 1.700;
+ int22_ar[G][U][U][G][A][A][U][G] = 2.000;
+ int22_ar[G][U][U][G][A][C][U][G] = 2.400;
+ int22_ar[G][U][U][G][A][G][U][G] = 1.100;
+ int22_ar[G][U][U][G][A][U][U][G] = 2.400;
+ int22_ar[G][U][U][G][C][A][U][G] = 2.000;
+ int22_ar[G][U][U][G][C][C][U][G] = 2.000;
+ int22_ar[G][U][U][G][C][G][U][G] = 2.000;
+ int22_ar[G][U][U][G][C][U][U][G] = 2.000;
+ int22_ar[G][U][U][G][G][A][U][G] = 2.000;
+ int22_ar[G][U][U][G][G][C][U][G] = 2.400;
+ int22_ar[G][U][U][G][G][G][U][G] = 0.700;
+ int22_ar[G][U][U][G][G][U][U][G] = 2.000;
+ int22_ar[G][U][U][G][U][A][U][G] = 2.000;
+ int22_ar[G][U][U][G][U][C][U][G] = 0.700;
+ int22_ar[G][U][U][G][U][G][U][G] = -2.500;
+ int22_ar[G][U][U][G][U][U][U][G] = 0.700;
+ int22_ar[G][U][U][U][A][A][U][G] = 2.000;
+ int22_ar[G][U][U][U][A][C][U][G] = 2.000;
+ int22_ar[G][U][U][U][A][G][U][G] = 2.000;
+ int22_ar[G][U][U][U][A][U][U][G] = 2.000;
+ int22_ar[G][U][U][U][C][A][U][G] = 2.000;
+ int22_ar[G][U][U][U][C][C][U][G] = 2.200;
+ int22_ar[G][U][U][U][C][G][U][G] = 1.000;
+ int22_ar[G][U][U][U][C][U][U][G] = 1.400;
+ int22_ar[G][U][U][U][G][A][U][G] = 2.000;
+ int22_ar[G][U][U][U][G][C][U][G] = 1.900;
+ int22_ar[G][U][U][U][G][G][U][G] = -1.200;
+ int22_ar[G][U][U][U][G][U][U][G] = 1.900;
+ int22_ar[G][U][U][U][U][A][U][G] = 2.000;
+ int22_ar[G][U][U][U][U][C][U][G] = 1.600;
+ int22_ar[G][U][U][U][U][G][U][G] = 1.300;
+ int22_ar[G][U][U][U][U][U][U][G] = 0.800;
+ int22_ar[U][A][A][A][A][A][A][U] = 2.800;
+ int22_ar[U][A][A][A][A][C][A][U] = 2.800;
+ int22_ar[U][A][A][A][A][G][A][U] = 1.700;
+ int22_ar[U][A][A][A][A][U][A][U] = 2.000;
+ int22_ar[U][A][A][A][C][A][A][U] = 2.500;
+ int22_ar[U][A][A][A][C][C][A][U] = 2.500;
+ int22_ar[U][A][A][A][C][G][A][U] = 1.500;
+ int22_ar[U][A][A][A][C][U][A][U] = 2.000;
+ int22_ar[U][A][A][A][G][A][A][U] = 1.500;
+ int22_ar[U][A][A][A][G][C][A][U] = 1.500;
+ int22_ar[U][A][A][A][G][G][A][U] = 0.500;
+ int22_ar[U][A][A][A][G][U][A][U] = 2.000;
+ int22_ar[U][A][A][A][U][A][A][U] = 2.000;
+ int22_ar[U][A][A][A][U][C][A][U] = 2.000;
+ int22_ar[U][A][A][A][U][G][A][U] = 2.000;
+ int22_ar[U][A][A][A][U][U][A][U] = 2.000;
+ int22_ar[U][A][A][C][A][A][A][U] = 2.600;
+ int22_ar[U][A][A][C][A][C][A][U] = 2.600;
+ int22_ar[U][A][A][C][A][G][A][U] = 1.600;
+ int22_ar[U][A][A][C][A][U][A][U] = 2.000;
+ int22_ar[U][A][A][C][C][A][A][U] = 3.100;
+ int22_ar[U][A][A][C][C][C][A][U] = 2.500;
+ int22_ar[U][A][A][C][C][G][A][U] = 2.400;
+ int22_ar[U][A][A][C][C][U][A][U] = 2.000;
+ int22_ar[U][A][A][C][G][A][A][U] = 2.000;
+ int22_ar[U][A][A][C][G][C][A][U] = 2.000;
+ int22_ar[U][A][A][C][G][G][A][U] = 2.000;
+ int22_ar[U][A][A][C][G][U][A][U] = 2.000;
+ int22_ar[U][A][A][C][U][A][A][U] = 3.100;
+ int22_ar[U][A][A][C][U][C][A][U] = 2.500;
+ int22_ar[U][A][A][C][U][G][A][U] = 2.400;
+ int22_ar[U][A][A][C][U][U][A][U] = 2.000;
+ int22_ar[U][A][A][G][A][A][A][U] = 1.500;
+ int22_ar[U][A][A][G][A][C][A][U] = 1.500;
+ int22_ar[U][A][A][G][A][G][A][U] = 0.500;
+ int22_ar[U][A][A][G][A][U][A][U] = 2.000;
+ int22_ar[U][A][A][G][C][A][A][U] = 2.000;
+ int22_ar[U][A][A][G][C][C][A][U] = 2.000;
+ int22_ar[U][A][A][G][C][G][A][U] = 2.000;
+ int22_ar[U][A][A][G][C][U][A][U] = 2.000;
+ int22_ar[U][A][A][G][G][A][A][U] = 2.100;
+ int22_ar[U][A][A][G][G][C][A][U] = 2.100;
+ int22_ar[U][A][A][G][G][G][A][U] = 1.000;
+ int22_ar[U][A][A][G][G][U][A][U] = 2.000;
+ int22_ar[U][A][A][G][U][A][A][U] = 1.300;
+ int22_ar[U][A][A][G][U][C][A][U] = 0.300;
+ int22_ar[U][A][A][G][U][G][A][U] = 1.100;
+ int22_ar[U][A][A][G][U][U][A][U] = 2.000;
+ int22_ar[U][A][A][U][A][A][A][U] = 2.000;
+ int22_ar[U][A][A][U][A][C][A][U] = 2.000;
+ int22_ar[U][A][A][U][A][G][A][U] = 2.000;
+ int22_ar[U][A][A][U][A][U][A][U] = 2.000;
+ int22_ar[U][A][A][U][C][A][A][U] = 3.100;
+ int22_ar[U][A][A][U][C][C][A][U] = 2.500;
+ int22_ar[U][A][A][U][C][G][A][U] = 2.400;
+ int22_ar[U][A][A][U][C][U][A][U] = 2.000;
+ int22_ar[U][A][A][U][G][A][A][U] = 2.300;
+ int22_ar[U][A][A][U][G][C][A][U] = 1.300;
+ int22_ar[U][A][A][U][G][G][A][U] = 2.100;
+ int22_ar[U][A][A][U][G][U][A][U] = 2.000;
+ int22_ar[U][A][A][U][U][A][A][U] = 2.700;
+ int22_ar[U][A][A][U][U][C][A][U] = 1.700;
+ int22_ar[U][A][A][U][U][G][A][U] = 2.400;
+ int22_ar[U][A][A][U][U][U][A][U] = 2.000;
+ int22_ar[U][A][C][A][A][A][A][U] = 2.300;
+ int22_ar[U][A][C][A][A][C][A][U] = 3.400;
+ int22_ar[U][A][C][A][A][G][A][U] = 2.000;
+ int22_ar[U][A][C][A][A][U][A][U] = 3.100;
+ int22_ar[U][A][C][A][C][A][A][U] = 2.100;
+ int22_ar[U][A][C][A][C][C][A][U] = 2.500;
+ int22_ar[U][A][C][A][C][G][A][U] = 2.000;
+ int22_ar[U][A][C][A][C][U][A][U] = 2.200;
+ int22_ar[U][A][C][A][G][A][A][U] = 1.100;
+ int22_ar[U][A][C][A][G][C][A][U] = 2.500;
+ int22_ar[U][A][C][A][G][G][A][U] = 2.000;
+ int22_ar[U][A][C][A][G][U][A][U] = 2.200;
+ int22_ar[U][A][C][A][U][A][A][U] = 2.000;
+ int22_ar[U][A][C][A][U][C][A][U] = 2.000;
+ int22_ar[U][A][C][A][U][G][A][U] = 2.000;
+ int22_ar[U][A][C][A][U][U][A][U] = 2.000;
+ int22_ar[U][A][C][C][A][A][A][U] = 2.200;
+ int22_ar[U][A][C][C][A][C][A][U] = 2.600;
+ int22_ar[U][A][C][C][A][G][A][U] = 2.000;
+ int22_ar[U][A][C][C][A][U][A][U] = 2.300;
+ int22_ar[U][A][C][C][C][A][A][U] = 2.000;
+ int22_ar[U][A][C][C][C][C][A][U] = 2.500;
+ int22_ar[U][A][C][C][C][G][A][U] = 2.000;
+ int22_ar[U][A][C][C][C][U][A][U] = 2.200;
+ int22_ar[U][A][C][C][G][A][A][U] = 2.000;
+ int22_ar[U][A][C][C][G][C][A][U] = 2.000;
+ int22_ar[U][A][C][C][G][G][A][U] = 2.000;
+ int22_ar[U][A][C][C][G][U][A][U] = 2.000;
+ int22_ar[U][A][C][C][U][A][A][U] = 2.000;
+ int22_ar[U][A][C][C][U][C][A][U] = 2.500;
+ int22_ar[U][A][C][C][U][G][A][U] = 2.000;
+ int22_ar[U][A][C][C][U][U][A][U] = 2.200;
+ int22_ar[U][A][C][G][A][A][A][U] = 1.100;
+ int22_ar[U][A][C][G][A][C][A][U] = 2.500;
+ int22_ar[U][A][C][G][A][G][A][U] = 2.000;
+ int22_ar[U][A][C][G][A][U][A][U] = 2.200;
+ int22_ar[U][A][C][G][C][A][A][U] = 2.000;
+ int22_ar[U][A][C][G][C][C][A][U] = 2.000;
+ int22_ar[U][A][C][G][C][G][A][U] = 2.000;
+ int22_ar[U][A][C][G][C][U][A][U] = 2.000;
+ int22_ar[U][A][C][G][G][A][A][U] = 1.600;
+ int22_ar[U][A][C][G][G][C][A][U] = 2.700;
+ int22_ar[U][A][C][G][G][G][A][U] = 2.000;
+ int22_ar[U][A][C][G][G][U][A][U] = 2.400;
+ int22_ar[U][A][C][G][U][A][A][U] = -0.100;
+ int22_ar[U][A][C][G][U][C][A][U] = 1.300;
+ int22_ar[U][A][C][G][U][G][A][U] = 2.000;
+ int22_ar[U][A][C][G][U][U][A][U] = 1.000;
+ int22_ar[U][A][C][U][A][A][A][U] = 2.000;
+ int22_ar[U][A][C][U][A][C][A][U] = 2.000;
+ int22_ar[U][A][C][U][A][G][A][U] = 2.000;
+ int22_ar[U][A][C][U][A][U][A][U] = 2.000;
+ int22_ar[U][A][C][U][C][A][A][U] = 2.000;
+ int22_ar[U][A][C][U][C][C][A][U] = 2.500;
+ int22_ar[U][A][C][U][C][G][A][U] = 2.000;
+ int22_ar[U][A][C][U][C][U][A][U] = 2.200;
+ int22_ar[U][A][C][U][G][A][A][U] = 0.900;
+ int22_ar[U][A][C][U][G][C][A][U] = 2.300;
+ int22_ar[U][A][C][U][G][G][A][U] = 2.000;
+ int22_ar[U][A][C][U][G][U][A][U] = 2.000;
+ int22_ar[U][A][C][U][U][A][A][U] = 1.200;
+ int22_ar[U][A][C][U][U][C][A][U] = 1.700;
+ int22_ar[U][A][C][U][U][G][A][U] = 2.000;
+ int22_ar[U][A][C][U][U][U][A][U] = 1.400;
+ int22_ar[U][A][G][A][A][A][A][U] = 1.700;
+ int22_ar[U][A][G][A][A][C][A][U] = 2.000;
+ int22_ar[U][A][G][A][A][G][A][U] = 2.100;
+ int22_ar[U][A][G][A][A][U][A][U] = 2.200;
+ int22_ar[U][A][G][A][C][A][A][U] = 1.500;
+ int22_ar[U][A][G][A][C][C][A][U] = 2.000;
+ int22_ar[U][A][G][A][C][G][A][U] = 1.900;
+ int22_ar[U][A][G][A][C][U][A][U] = 1.000;
+ int22_ar[U][A][G][A][G][A][A][U] = 0.500;
+ int22_ar[U][A][G][A][G][C][A][U] = 2.000;
+ int22_ar[U][A][G][A][G][G][A][U] = 0.900;
+ int22_ar[U][A][G][A][G][U][A][U] = 1.800;
+ int22_ar[U][A][G][A][U][A][A][U] = 2.000;
+ int22_ar[U][A][G][A][U][C][A][U] = 2.000;
+ int22_ar[U][A][G][A][U][G][A][U] = 2.000;
+ int22_ar[U][A][G][A][U][U][A][U] = 2.000;
+ int22_ar[U][A][G][C][A][A][A][U] = 1.600;
+ int22_ar[U][A][G][C][A][C][A][U] = 2.000;
+ int22_ar[U][A][G][C][A][G][A][U] = 2.000;
+ int22_ar[U][A][G][C][A][U][A][U] = 1.100;
+ int22_ar[U][A][G][C][C][A][A][U] = 2.400;
+ int22_ar[U][A][G][C][C][C][A][U] = 2.000;
+ int22_ar[U][A][G][C][C][G][A][U] = 2.400;
+ int22_ar[U][A][G][C][C][U][A][U] = 1.900;
+ int22_ar[U][A][G][C][G][A][A][U] = 2.000;
+ int22_ar[U][A][G][C][G][C][A][U] = 2.000;
+ int22_ar[U][A][G][C][G][G][A][U] = 2.000;
+ int22_ar[U][A][G][C][G][U][A][U] = 2.000;
+ int22_ar[U][A][G][C][U][A][A][U] = 2.400;
+ int22_ar[U][A][G][C][U][C][A][U] = 2.000;
+ int22_ar[U][A][G][C][U][G][A][U] = 2.400;
+ int22_ar[U][A][G][C][U][U][A][U] = 1.900;
+ int22_ar[U][A][G][G][A][A][A][U] = 0.500;
+ int22_ar[U][A][G][G][A][C][A][U] = 2.000;
+ int22_ar[U][A][G][G][A][G][A][U] = 0.900;
+ int22_ar[U][A][G][G][A][U][A][U] = 1.800;
+ int22_ar[U][A][G][G][C][A][A][U] = 2.000;
+ int22_ar[U][A][G][G][C][C][A][U] = 2.000;
+ int22_ar[U][A][G][G][C][G][A][U] = 2.000;
+ int22_ar[U][A][G][G][C][U][A][U] = 2.000;
+ int22_ar[U][A][G][G][G][A][A][U] = 1.000;
+ int22_ar[U][A][G][G][G][C][A][U] = 2.000;
+ int22_ar[U][A][G][G][G][G][A][U] = 1.400;
+ int22_ar[U][A][G][G][G][U][A][U] = 1.500;
+ int22_ar[U][A][G][G][U][A][A][U] = 1.100;
+ int22_ar[U][A][G][G][U][C][A][U] = 2.000;
+ int22_ar[U][A][G][G][U][G][A][U] = 0.700;
+ int22_ar[U][A][G][G][U][U][A][U] = -1.200;
+ int22_ar[U][A][G][U][A][A][A][U] = 2.000;
+ int22_ar[U][A][G][U][A][C][A][U] = 2.000;
+ int22_ar[U][A][G][U][A][G][A][U] = 2.000;
+ int22_ar[U][A][G][U][A][U][A][U] = 2.000;
+ int22_ar[U][A][G][U][C][A][A][U] = 2.400;
+ int22_ar[U][A][G][U][C][C][A][U] = 2.000;
+ int22_ar[U][A][G][U][C][G][A][U] = 2.400;
+ int22_ar[U][A][G][U][C][U][A][U] = 1.900;
+ int22_ar[U][A][G][U][G][A][A][U] = 2.100;
+ int22_ar[U][A][G][U][G][C][A][U] = 2.000;
+ int22_ar[U][A][G][U][G][G][A][U] = 1.700;
+ int22_ar[U][A][G][U][G][U][A][U] = -0.200;
+ int22_ar[U][A][G][U][U][A][A][U] = 2.400;
+ int22_ar[U][A][G][U][U][C][A][U] = 2.000;
+ int22_ar[U][A][G][U][U][G][A][U] = 2.000;
+ int22_ar[U][A][G][U][U][U][A][U] = 1.900;
+ int22_ar[U][A][U][A][A][A][A][U] = 2.000;
+ int22_ar[U][A][U][A][A][C][A][U] = 3.400;
+ int22_ar[U][A][U][A][A][G][A][U] = 1.000;
+ int22_ar[U][A][U][A][A][U][A][U] = 2.900;
+ int22_ar[U][A][U][A][C][A][A][U] = 2.000;
+ int22_ar[U][A][U][A][C][C][A][U] = 2.500;
+ int22_ar[U][A][U][A][C][G][A][U] = -0.300;
+ int22_ar[U][A][U][A][C][U][A][U] = 1.700;
+ int22_ar[U][A][U][A][G][A][A][U] = 2.000;
+ int22_ar[U][A][U][A][G][C][A][U] = 2.500;
+ int22_ar[U][A][U][A][G][G][A][U] = 0.500;
+ int22_ar[U][A][U][A][G][U][A][U] = 2.500;
+ int22_ar[U][A][U][A][U][A][A][U] = 2.000;
+ int22_ar[U][A][U][A][U][C][A][U] = 2.000;
+ int22_ar[U][A][U][A][U][G][A][U] = 2.000;
+ int22_ar[U][A][U][A][U][U][A][U] = 2.000;
+ int22_ar[U][A][U][C][A][A][A][U] = 2.000;
+ int22_ar[U][A][U][C][A][C][A][U] = 2.600;
+ int22_ar[U][A][U][C][A][G][A][U] = -0.200;
+ int22_ar[U][A][U][C][A][U][A][U] = 1.800;
+ int22_ar[U][A][U][C][C][A][A][U] = 2.000;
+ int22_ar[U][A][U][C][C][C][A][U] = 2.500;
+ int22_ar[U][A][U][C][C][G][A][U] = 0.700;
+ int22_ar[U][A][U][C][C][U][A][U] = 1.600;
+ int22_ar[U][A][U][C][G][A][A][U] = 2.000;
+ int22_ar[U][A][U][C][G][C][A][U] = 2.000;
+ int22_ar[U][A][U][C][G][G][A][U] = 2.000;
+ int22_ar[U][A][U][C][G][U][A][U] = 2.000;
+ int22_ar[U][A][U][C][U][A][A][U] = 2.000;
+ int22_ar[U][A][U][C][U][C][A][U] = 2.500;
+ int22_ar[U][A][U][C][U][G][A][U] = 0.700;
+ int22_ar[U][A][U][C][U][U][A][U] = 1.600;
+ int22_ar[U][A][U][G][A][A][A][U] = 2.000;
+ int22_ar[U][A][U][G][A][C][A][U] = 2.500;
+ int22_ar[U][A][U][G][A][G][A][U] = 0.500;
+ int22_ar[U][A][U][G][A][U][A][U] = 2.500;
+ int22_ar[U][A][U][G][C][A][A][U] = 2.000;
+ int22_ar[U][A][U][G][C][C][A][U] = 2.000;
+ int22_ar[U][A][U][G][C][G][A][U] = 2.000;
+ int22_ar[U][A][U][G][C][U][A][U] = 2.000;
+ int22_ar[U][A][U][G][G][A][A][U] = 2.000;
+ int22_ar[U][A][U][G][G][C][A][U] = 2.700;
+ int22_ar[U][A][U][G][G][G][A][U] = 0.300;
+ int22_ar[U][A][U][G][G][U][A][U] = 2.200;
+ int22_ar[U][A][U][G][U][A][A][U] = 2.000;
+ int22_ar[U][A][U][G][U][C][A][U] = 1.300;
+ int22_ar[U][A][U][G][U][G][A][U] = -2.500;
+ int22_ar[U][A][U][G][U][U][A][U] = 1.300;
+ int22_ar[U][A][U][U][A][A][A][U] = 2.000;
+ int22_ar[U][A][U][U][A][C][A][U] = 2.000;
+ int22_ar[U][A][U][U][A][G][A][U] = 2.000;
+ int22_ar[U][A][U][U][A][U][A][U] = 2.000;
+ int22_ar[U][A][U][U][C][A][A][U] = 2.000;
+ int22_ar[U][A][U][U][C][C][A][U] = 2.500;
+ int22_ar[U][A][U][U][C][G][A][U] = 0.700;
+ int22_ar[U][A][U][U][C][U][A][U] = 1.600;
+ int22_ar[U][A][U][U][G][A][A][U] = 2.000;
+ int22_ar[U][A][U][U][G][C][A][U] = 2.300;
+ int22_ar[U][A][U][U][G][G][A][U] = -1.500;
+ int22_ar[U][A][U][U][G][U][A][U] = 2.300;
+ int22_ar[U][A][U][U][U][A][A][U] = 2.000;
+ int22_ar[U][A][U][U][U][C][A][U] = 1.700;
+ int22_ar[U][A][U][U][U][G][A][U] = 0.700;
+ int22_ar[U][A][U][U][U][U][A][U] = 0.800;
+ int22_ar[U][A][A][A][A][A][C][G] = 2.000;
+ int22_ar[U][A][A][A][A][C][C][G] = 2.000;
+ int22_ar[U][A][A][A][A][G][C][G] = 1.000;
+ int22_ar[U][A][A][A][A][U][C][G] = 2.000;
+ int22_ar[U][A][A][A][C][A][C][G] = 1.900;
+ int22_ar[U][A][A][A][C][C][C][G] = 1.900;
+ int22_ar[U][A][A][A][C][G][C][G] = 0.900;
+ int22_ar[U][A][A][A][C][U][C][G] = 2.000;
+ int22_ar[U][A][A][A][G][A][C][G] = 1.000;
+ int22_ar[U][A][A][A][G][C][C][G] = 1.000;
+ int22_ar[U][A][A][A][G][G][C][G] = 0.000;
+ int22_ar[U][A][A][A][G][U][C][G] = 2.000;
+ int22_ar[U][A][A][A][U][A][C][G] = 2.000;
+ int22_ar[U][A][A][A][U][C][C][G] = 2.000;
+ int22_ar[U][A][A][A][U][G][C][G] = 2.000;
+ int22_ar[U][A][A][A][U][U][C][G] = 2.000;
+ int22_ar[U][A][A][C][A][A][C][G] = 2.400;
+ int22_ar[U][A][A][C][A][C][C][G] = 2.400;
+ int22_ar[U][A][A][C][A][G][C][G] = 1.300;
+ int22_ar[U][A][A][C][A][U][C][G] = 2.000;
+ int22_ar[U][A][A][C][C][A][C][G] = 2.800;
+ int22_ar[U][A][A][C][C][C][C][G] = 2.200;
+ int22_ar[U][A][A][C][C][G][C][G] = 2.200;
+ int22_ar[U][A][A][C][C][U][C][G] = 2.000;
+ int22_ar[U][A][A][C][G][A][C][G] = 2.000;
+ int22_ar[U][A][A][C][G][C][C][G] = 2.000;
+ int22_ar[U][A][A][C][G][G][C][G] = 2.000;
+ int22_ar[U][A][A][C][G][U][C][G] = 2.000;
+ int22_ar[U][A][A][C][U][A][C][G] = 2.700;
+ int22_ar[U][A][A][C][U][C][C][G] = 2.100;
+ int22_ar[U][A][A][C][U][G][C][G] = 2.000;
+ int22_ar[U][A][A][C][U][U][C][G] = 2.000;
+ int22_ar[U][A][A][G][A][A][C][G] = 1.000;
+ int22_ar[U][A][A][G][A][C][C][G] = 1.000;
+ int22_ar[U][A][A][G][A][G][C][G] = 0.000;
+ int22_ar[U][A][A][G][A][U][C][G] = 2.000;
+ int22_ar[U][A][A][G][C][A][C][G] = 2.000;
+ int22_ar[U][A][A][G][C][C][C][G] = 2.000;
+ int22_ar[U][A][A][G][C][G][C][G] = 2.000;
+ int22_ar[U][A][A][G][C][U][C][G] = 2.000;
+ int22_ar[U][A][A][G][G][A][C][G] = 1.800;
+ int22_ar[U][A][A][G][G][C][C][G] = 1.800;
+ int22_ar[U][A][A][G][G][G][C][G] = 0.700;
+ int22_ar[U][A][A][G][G][U][C][G] = 2.000;
+ int22_ar[U][A][A][G][U][A][C][G] = 0.300;
+ int22_ar[U][A][A][G][U][C][C][G] = -0.700;
+ int22_ar[U][A][A][G][U][G][C][G] = 0.100;
+ int22_ar[U][A][A][G][U][U][C][G] = 2.000;
+ int22_ar[U][A][A][U][A][A][C][G] = 2.000;
+ int22_ar[U][A][A][U][A][C][C][G] = 2.000;
+ int22_ar[U][A][A][U][A][G][C][G] = 2.000;
+ int22_ar[U][A][A][U][A][U][C][G] = 2.000;
+ int22_ar[U][A][A][U][C][A][C][G] = 2.700;
+ int22_ar[U][A][A][U][C][C][C][G] = 2.100;
+ int22_ar[U][A][A][U][C][G][C][G] = 2.000;
+ int22_ar[U][A][A][U][C][U][C][G] = 2.000;
+ int22_ar[U][A][A][U][G][A][C][G] = 1.800;
+ int22_ar[U][A][A][U][G][C][C][G] = 0.800;
+ int22_ar[U][A][A][U][G][G][C][G] = 1.600;
+ int22_ar[U][A][A][U][G][U][C][G] = 2.000;
+ int22_ar[U][A][A][U][U][A][C][G] = 2.200;
+ int22_ar[U][A][A][U][U][C][C][G] = 1.200;
+ int22_ar[U][A][A][U][U][G][C][G] = 1.900;
+ int22_ar[U][A][A][U][U][U][C][G] = 2.000;
+ int22_ar[U][A][C][A][A][A][C][G] = 1.600;
+ int22_ar[U][A][C][A][A][C][C][G] = 2.600;
+ int22_ar[U][A][C][A][A][G][C][G] = 2.000;
+ int22_ar[U][A][C][A][A][U][C][G] = 2.300;
+ int22_ar[U][A][C][A][C][A][C][G] = 1.500;
+ int22_ar[U][A][C][A][C][C][C][G] = 1.900;
+ int22_ar[U][A][C][A][C][G][C][G] = 2.000;
+ int22_ar[U][A][C][A][C][U][C][G] = 1.600;
+ int22_ar[U][A][C][A][G][A][C][G] = 0.600;
+ int22_ar[U][A][C][A][G][C][C][G] = 2.000;
+ int22_ar[U][A][C][A][G][G][C][G] = 2.000;
+ int22_ar[U][A][C][A][G][U][C][G] = 1.700;
+ int22_ar[U][A][C][A][U][A][C][G] = 2.000;
+ int22_ar[U][A][C][A][U][C][C][G] = 2.000;
+ int22_ar[U][A][C][A][U][G][C][G] = 2.000;
+ int22_ar[U][A][C][A][U][U][C][G] = 2.000;
+ int22_ar[U][A][C][C][A][A][C][G] = 1.900;
+ int22_ar[U][A][C][C][A][C][C][G] = 2.400;
+ int22_ar[U][A][C][C][A][G][C][G] = 2.000;
+ int22_ar[U][A][C][C][A][U][C][G] = 2.100;
+ int22_ar[U][A][C][C][C][A][C][G] = 1.800;
+ int22_ar[U][A][C][C][C][C][C][G] = 2.200;
+ int22_ar[U][A][C][C][C][G][C][G] = 2.000;
+ int22_ar[U][A][C][C][C][U][C][G] = 1.900;
+ int22_ar[U][A][C][C][G][A][C][G] = 2.000;
+ int22_ar[U][A][C][C][G][C][C][G] = 2.000;
+ int22_ar[U][A][C][C][G][G][C][G] = 2.000;
+ int22_ar[U][A][C][C][G][U][C][G] = 2.000;
+ int22_ar[U][A][C][C][U][A][C][G] = 1.600;
+ int22_ar[U][A][C][C][U][C][C][G] = 2.100;
+ int22_ar[U][A][C][C][U][G][C][G] = 2.000;
+ int22_ar[U][A][C][C][U][U][C][G] = 1.800;
+ int22_ar[U][A][C][G][A][A][C][G] = 0.600;
+ int22_ar[U][A][C][G][A][C][C][G] = 2.000;
+ int22_ar[U][A][C][G][A][G][C][G] = 2.000;
+ int22_ar[U][A][C][G][A][U][C][G] = 1.700;
+ int22_ar[U][A][C][G][C][A][C][G] = 2.000;
+ int22_ar[U][A][C][G][C][C][C][G] = 2.000;
+ int22_ar[U][A][C][G][C][G][C][G] = 2.000;
+ int22_ar[U][A][C][G][C][U][C][G] = 2.000;
+ int22_ar[U][A][C][G][G][A][C][G] = 1.300;
+ int22_ar[U][A][C][G][G][C][C][G] = 2.400;
+ int22_ar[U][A][C][G][G][G][C][G] = 2.000;
+ int22_ar[U][A][C][G][G][U][C][G] = 2.100;
+ int22_ar[U][A][C][G][U][A][C][G] = -1.100;
+ int22_ar[U][A][C][G][U][C][C][G] = 0.300;
+ int22_ar[U][A][C][G][U][G][C][G] = 2.000;
+ int22_ar[U][A][C][G][U][U][C][G] = 0.000;
+ int22_ar[U][A][C][U][A][A][C][G] = 2.000;
+ int22_ar[U][A][C][U][A][C][C][G] = 2.000;
+ int22_ar[U][A][C][U][A][G][C][G] = 2.000;
+ int22_ar[U][A][C][U][A][U][C][G] = 2.000;
+ int22_ar[U][A][C][U][C][A][C][G] = 1.600;
+ int22_ar[U][A][C][U][C][C][C][G] = 2.100;
+ int22_ar[U][A][C][U][C][G][C][G] = 2.000;
+ int22_ar[U][A][C][U][C][U][C][G] = 1.800;
+ int22_ar[U][A][C][U][G][A][C][G] = 0.400;
+ int22_ar[U][A][C][U][G][C][C][G] = 1.800;
+ int22_ar[U][A][C][U][G][G][C][G] = 2.000;
+ int22_ar[U][A][C][U][G][U][C][G] = 1.500;
+ int22_ar[U][A][C][U][U][A][C][G] = 0.700;
+ int22_ar[U][A][C][U][U][C][C][G] = 1.200;
+ int22_ar[U][A][C][U][U][G][C][G] = 2.000;
+ int22_ar[U][A][C][U][U][U][C][G] = 0.900;
+ int22_ar[U][A][G][A][A][A][C][G] = 1.000;
+ int22_ar[U][A][G][A][A][C][C][G] = 2.000;
+ int22_ar[U][A][G][A][A][G][C][G] = 1.400;
+ int22_ar[U][A][G][A][A][U][C][G] = 1.500;
+ int22_ar[U][A][G][A][C][A][C][G] = 0.900;
+ int22_ar[U][A][G][A][C][C][C][G] = 2.000;
+ int22_ar[U][A][G][A][C][G][C][G] = 1.300;
+ int22_ar[U][A][G][A][C][U][C][G] = 0.400;
+ int22_ar[U][A][G][A][G][A][C][G] = 0.000;
+ int22_ar[U][A][G][A][G][C][C][G] = 2.000;
+ int22_ar[U][A][G][A][G][G][C][G] = 0.400;
+ int22_ar[U][A][G][A][G][U][C][G] = 1.300;
+ int22_ar[U][A][G][A][U][A][C][G] = 2.000;
+ int22_ar[U][A][G][A][U][C][C][G] = 2.000;
+ int22_ar[U][A][G][A][U][G][C][G] = 2.000;
+ int22_ar[U][A][G][A][U][U][C][G] = 2.000;
+ int22_ar[U][A][G][C][A][A][C][G] = 1.300;
+ int22_ar[U][A][G][C][A][C][C][G] = 2.000;
+ int22_ar[U][A][G][C][A][G][C][G] = 1.700;
+ int22_ar[U][A][G][C][A][U][C][G] = 0.800;
+ int22_ar[U][A][G][C][C][A][C][G] = 2.200;
+ int22_ar[U][A][G][C][C][C][C][G] = 2.000;
+ int22_ar[U][A][G][C][C][G][C][G] = 2.200;
+ int22_ar[U][A][G][C][C][U][C][G] = 1.700;
+ int22_ar[U][A][G][C][G][A][C][G] = 2.000;
+ int22_ar[U][A][G][C][G][C][C][G] = 2.000;
+ int22_ar[U][A][G][C][G][G][C][G] = 2.000;
+ int22_ar[U][A][G][C][G][U][C][G] = 2.000;
+ int22_ar[U][A][G][C][U][A][C][G] = 2.000;
+ int22_ar[U][A][G][C][U][C][C][G] = 2.000;
+ int22_ar[U][A][G][C][U][G][C][G] = 2.000;
+ int22_ar[U][A][G][C][U][U][C][G] = 1.500;
+ int22_ar[U][A][G][G][A][A][C][G] = 0.000;
+ int22_ar[U][A][G][G][A][C][C][G] = 2.000;
+ int22_ar[U][A][G][G][A][G][C][G] = 0.400;
+ int22_ar[U][A][G][G][A][U][C][G] = 1.300;
+ int22_ar[U][A][G][G][C][A][C][G] = 2.000;
+ int22_ar[U][A][G][G][C][C][C][G] = 2.000;
+ int22_ar[U][A][G][G][C][G][C][G] = 2.000;
+ int22_ar[U][A][G][G][C][U][C][G] = 2.000;
+ int22_ar[U][A][G][G][G][A][C][G] = 0.700;
+ int22_ar[U][A][G][G][G][C][C][G] = 2.000;
+ int22_ar[U][A][G][G][G][G][C][G] = 1.100;
+ int22_ar[U][A][G][G][G][U][C][G] = 1.200;
+ int22_ar[U][A][G][G][U][A][C][G] = 0.100;
+ int22_ar[U][A][G][G][U][C][C][G] = 2.000;
+ int22_ar[U][A][G][G][U][G][C][G] = -0.300;
+ int22_ar[U][A][G][G][U][U][C][G] = -2.200;
+ int22_ar[U][A][G][U][A][A][C][G] = 2.000;
+ int22_ar[U][A][G][U][A][C][C][G] = 2.000;
+ int22_ar[U][A][G][U][A][G][C][G] = 2.000;
+ int22_ar[U][A][G][U][A][U][C][G] = 2.000;
+ int22_ar[U][A][G][U][C][A][C][G] = 2.000;
+ int22_ar[U][A][G][U][C][C][C][G] = 2.000;
+ int22_ar[U][A][G][U][C][G][C][G] = 2.000;
+ int22_ar[U][A][G][U][C][U][C][G] = 1.500;
+ int22_ar[U][A][G][U][G][A][C][G] = 1.600;
+ int22_ar[U][A][G][U][G][C][C][G] = 2.000;
+ int22_ar[U][A][G][U][G][G][C][G] = 1.200;
+ int22_ar[U][A][G][U][G][U][C][G] = -0.700;
+ int22_ar[U][A][G][U][U][A][C][G] = 1.900;
+ int22_ar[U][A][G][U][U][C][C][G] = 2.000;
+ int22_ar[U][A][G][U][U][G][C][G] = 1.500;
+ int22_ar[U][A][G][U][U][U][C][G] = 1.500;
+ int22_ar[U][A][U][A][A][A][C][G] = 2.000;
+ int22_ar[U][A][U][A][A][C][C][G] = 2.600;
+ int22_ar[U][A][U][A][A][G][C][G] = 0.200;
+ int22_ar[U][A][U][A][A][U][C][G] = 2.200;
+ int22_ar[U][A][U][A][C][A][C][G] = 2.000;
+ int22_ar[U][A][U][A][C][C][C][G] = 1.900;
+ int22_ar[U][A][U][A][C][G][C][G] = -0.900;
+ int22_ar[U][A][U][A][C][U][C][G] = 1.100;
+ int22_ar[U][A][U][A][G][A][C][G] = 2.000;
+ int22_ar[U][A][U][A][G][C][C][G] = 2.000;
+ int22_ar[U][A][U][A][G][G][C][G] = 0.000;
+ int22_ar[U][A][U][A][G][U][C][G] = 2.000;
+ int22_ar[U][A][U][A][U][A][C][G] = 2.000;
+ int22_ar[U][A][U][A][U][C][C][G] = 2.000;
+ int22_ar[U][A][U][A][U][G][C][G] = 2.000;
+ int22_ar[U][A][U][A][U][U][C][G] = 2.000;
+ int22_ar[U][A][U][C][A][A][C][G] = 2.000;
+ int22_ar[U][A][U][C][A][C][C][G] = 2.400;
+ int22_ar[U][A][U][C][A][G][C][G] = -0.400;
+ int22_ar[U][A][U][C][A][U][C][G] = 1.500;
+ int22_ar[U][A][U][C][C][A][C][G] = 2.000;
+ int22_ar[U][A][U][C][C][C][C][G] = 2.200;
+ int22_ar[U][A][U][C][C][G][C][G] = 0.400;
+ int22_ar[U][A][U][C][C][U][C][G] = 1.400;
+ int22_ar[U][A][U][C][G][A][C][G] = 2.000;
+ int22_ar[U][A][U][C][G][C][C][G] = 2.000;
+ int22_ar[U][A][U][C][G][G][C][G] = 2.000;
+ int22_ar[U][A][U][C][G][U][C][G] = 2.000;
+ int22_ar[U][A][U][C][U][A][C][G] = 2.000;
+ int22_ar[U][A][U][C][U][C][C][G] = 2.100;
+ int22_ar[U][A][U][C][U][G][C][G] = 0.300;
+ int22_ar[U][A][U][C][U][U][C][G] = 1.200;
+ int22_ar[U][A][U][G][A][A][C][G] = 2.000;
+ int22_ar[U][A][U][G][A][C][C][G] = 2.000;
+ int22_ar[U][A][U][G][A][G][C][G] = 0.000;
+ int22_ar[U][A][U][G][A][U][C][G] = 2.000;
+ int22_ar[U][A][U][G][C][A][C][G] = 2.000;
+ int22_ar[U][A][U][G][C][C][C][G] = 2.000;
+ int22_ar[U][A][U][G][C][G][C][G] = 2.000;
+ int22_ar[U][A][U][G][C][U][C][G] = 2.000;
+ int22_ar[U][A][U][G][G][A][C][G] = 2.000;
+ int22_ar[U][A][U][G][G][C][C][G] = 2.400;
+ int22_ar[U][A][U][G][G][G][C][G] = 0.000;
+ int22_ar[U][A][U][G][G][U][C][G] = 1.900;
+ int22_ar[U][A][U][G][U][A][C][G] = 2.000;
+ int22_ar[U][A][U][G][U][C][C][G] = 0.300;
+ int22_ar[U][A][U][G][U][G][C][G] = -3.500;
+ int22_ar[U][A][U][G][U][U][C][G] = 0.300;
+ int22_ar[U][A][U][U][A][A][C][G] = 2.000;
+ int22_ar[U][A][U][U][A][C][C][G] = 2.000;
+ int22_ar[U][A][U][U][A][G][C][G] = 2.000;
+ int22_ar[U][A][U][U][A][U][C][G] = 2.000;
+ int22_ar[U][A][U][U][C][A][C][G] = 2.000;
+ int22_ar[U][A][U][U][C][C][C][G] = 2.100;
+ int22_ar[U][A][U][U][C][G][C][G] = 0.300;
+ int22_ar[U][A][U][U][C][U][C][G] = 1.200;
+ int22_ar[U][A][U][U][G][A][C][G] = 2.000;
+ int22_ar[U][A][U][U][G][C][C][G] = 1.800;
+ int22_ar[U][A][U][U][G][G][C][G] = -2.000;
+ int22_ar[U][A][U][U][G][U][C][G] = 1.800;
+ int22_ar[U][A][U][U][U][A][C][G] = 2.000;
+ int22_ar[U][A][U][U][U][C][C][G] = 1.200;
+ int22_ar[U][A][U][U][U][G][C][G] = 0.200;
+ int22_ar[U][A][U][U][U][U][C][G] = 0.300;
+ int22_ar[U][A][A][A][A][A][G][C] = 2.100;
+ int22_ar[U][A][A][A][A][C][G][C] = 2.100;
+ int22_ar[U][A][A][A][A][G][G][C] = 1.100;
+ int22_ar[U][A][A][A][A][U][G][C] = 2.000;
+ int22_ar[U][A][A][A][C][A][G][C] = 1.900;
+ int22_ar[U][A][A][A][C][C][G][C] = 1.900;
+ int22_ar[U][A][A][A][C][G][G][C] = 0.800;
+ int22_ar[U][A][A][A][C][U][G][C] = 2.000;
+ int22_ar[U][A][A][A][G][A][G][C] = 0.100;
+ int22_ar[U][A][A][A][G][C][G][C] = 0.100;
+ int22_ar[U][A][A][A][G][G][G][C] = -0.900;
+ int22_ar[U][A][A][A][G][U][G][C] = 2.000;
+ int22_ar[U][A][A][A][U][A][G][C] = 2.000;
+ int22_ar[U][A][A][A][U][C][G][C] = 2.000;
+ int22_ar[U][A][A][A][U][G][G][C] = 2.000;
+ int22_ar[U][A][A][A][U][U][G][C] = 2.000;
+ int22_ar[U][A][A][C][A][A][G][C] = 1.800;
+ int22_ar[U][A][A][C][A][C][G][C] = 1.800;
+ int22_ar[U][A][A][C][A][G][G][C] = 0.800;
+ int22_ar[U][A][A][C][A][U][G][C] = 2.000;
+ int22_ar[U][A][A][C][C][A][G][C] = 2.500;
+ int22_ar[U][A][A][C][C][C][G][C] = 1.900;
+ int22_ar[U][A][A][C][C][G][G][C] = 1.800;
+ int22_ar[U][A][A][C][C][U][G][C] = 2.000;
+ int22_ar[U][A][A][C][G][A][G][C] = 2.000;
+ int22_ar[U][A][A][C][G][C][G][C] = 2.000;
+ int22_ar[U][A][A][C][G][G][G][C] = 2.000;
+ int22_ar[U][A][A][C][G][U][G][C] = 2.000;
+ int22_ar[U][A][A][C][U][A][G][C] = 1.500;
+ int22_ar[U][A][A][C][U][C][G][C] = 0.900;
+ int22_ar[U][A][A][C][U][G][G][C] = 0.900;
+ int22_ar[U][A][A][C][U][U][G][C] = 2.000;
+ int22_ar[U][A][A][G][A][A][G][C] = 0.700;
+ int22_ar[U][A][A][G][A][C][G][C] = 0.700;
+ int22_ar[U][A][A][G][A][G][G][C] = -0.300;
+ int22_ar[U][A][A][G][A][U][G][C] = 2.000;
+ int22_ar[U][A][A][G][C][A][G][C] = 2.000;
+ int22_ar[U][A][A][G][C][C][G][C] = 2.000;
+ int22_ar[U][A][A][G][C][G][G][C] = 2.000;
+ int22_ar[U][A][A][G][C][U][G][C] = 2.000;
+ int22_ar[U][A][A][G][G][A][G][C] = 1.800;
+ int22_ar[U][A][A][G][G][C][G][C] = 1.800;
+ int22_ar[U][A][A][G][G][G][G][C] = 0.700;
+ int22_ar[U][A][A][G][G][U][G][C] = 2.000;
+ int22_ar[U][A][A][G][U][A][G][C] = 0.000;
+ int22_ar[U][A][A][G][U][C][G][C] = -1.000;
+ int22_ar[U][A][A][G][U][G][G][C] = -0.300;
+ int22_ar[U][A][A][G][U][U][G][C] = 2.000;
+ int22_ar[U][A][A][U][A][A][G][C] = 2.000;
+ int22_ar[U][A][A][U][A][C][G][C] = 2.000;
+ int22_ar[U][A][A][U][A][G][G][C] = 2.000;
+ int22_ar[U][A][A][U][A][U][G][C] = 2.000;
+ int22_ar[U][A][A][U][C][A][G][C] = 2.500;
+ int22_ar[U][A][A][U][C][C][G][C] = 1.900;
+ int22_ar[U][A][A][U][C][G][G][C] = 1.900;
+ int22_ar[U][A][A][U][C][U][G][C] = 2.000;
+ int22_ar[U][A][A][U][G][A][G][C] = 0.400;
+ int22_ar[U][A][A][U][G][C][G][C] = -0.600;
+ int22_ar[U][A][A][U][G][G][G][C] = 0.100;
+ int22_ar[U][A][A][U][G][U][G][C] = 2.000;
+ int22_ar[U][A][A][U][U][A][G][C] = 2.100;
+ int22_ar[U][A][A][U][U][C][G][C] = 1.100;
+ int22_ar[U][A][A][U][U][G][G][C] = 1.900;
+ int22_ar[U][A][A][U][U][U][G][C] = 2.000;
+ int22_ar[U][A][C][A][A][A][G][C] = 1.700;
+ int22_ar[U][A][C][A][A][C][G][C] = 2.700;
+ int22_ar[U][A][C][A][A][G][G][C] = 2.000;
+ int22_ar[U][A][C][A][A][U][G][C] = 2.400;
+ int22_ar[U][A][C][A][C][A][G][C] = 1.400;
+ int22_ar[U][A][C][A][C][C][G][C] = 1.900;
+ int22_ar[U][A][C][A][C][G][G][C] = 2.000;
+ int22_ar[U][A][C][A][C][U][G][C] = 1.600;
+ int22_ar[U][A][C][A][G][A][G][C] = -0.300;
+ int22_ar[U][A][C][A][G][C][G][C] = 1.100;
+ int22_ar[U][A][C][A][G][G][G][C] = 2.000;
+ int22_ar[U][A][C][A][G][U][G][C] = 0.800;
+ int22_ar[U][A][C][A][U][A][G][C] = 2.000;
+ int22_ar[U][A][C][A][U][C][G][C] = 2.000;
+ int22_ar[U][A][C][A][U][G][G][C] = 2.000;
+ int22_ar[U][A][C][A][U][U][G][C] = 2.000;
+ int22_ar[U][A][C][C][A][A][G][C] = 1.400;
+ int22_ar[U][A][C][C][A][C][G][C] = 1.800;
+ int22_ar[U][A][C][C][A][G][G][C] = 2.000;
+ int22_ar[U][A][C][C][A][U][G][C] = 1.500;
+ int22_ar[U][A][C][C][C][A][G][C] = 1.400;
+ int22_ar[U][A][C][C][C][C][G][C] = 1.900;
+ int22_ar[U][A][C][C][C][G][G][C] = 2.000;
+ int22_ar[U][A][C][C][C][U][G][C] = 1.600;
+ int22_ar[U][A][C][C][G][A][G][C] = 2.000;
+ int22_ar[U][A][C][C][G][C][G][C] = 2.000;
+ int22_ar[U][A][C][C][G][G][G][C] = 2.000;
+ int22_ar[U][A][C][C][G][U][G][C] = 2.000;
+ int22_ar[U][A][C][C][U][A][G][C] = 0.400;
+ int22_ar[U][A][C][C][U][C][G][C] = 0.900;
+ int22_ar[U][A][C][C][U][G][G][C] = 2.000;
+ int22_ar[U][A][C][C][U][U][G][C] = 0.600;
+ int22_ar[U][A][C][G][A][A][G][C] = 0.300;
+ int22_ar[U][A][C][G][A][C][G][C] = 1.700;
+ int22_ar[U][A][C][G][A][G][G][C] = 2.000;
+ int22_ar[U][A][C][G][A][U][G][C] = 1.400;
+ int22_ar[U][A][C][G][C][A][G][C] = 2.000;
+ int22_ar[U][A][C][G][C][C][G][C] = 2.000;
+ int22_ar[U][A][C][G][C][G][G][C] = 2.000;
+ int22_ar[U][A][C][G][C][U][G][C] = 2.000;
+ int22_ar[U][A][C][G][G][A][G][C] = 1.300;
+ int22_ar[U][A][C][G][G][C][G][C] = 2.400;
+ int22_ar[U][A][C][G][G][G][G][C] = 2.000;
+ int22_ar[U][A][C][G][G][U][G][C] = 2.100;
+ int22_ar[U][A][C][G][U][A][G][C] = -1.500;
+ int22_ar[U][A][C][G][U][C][G][C] = 0.000;
+ int22_ar[U][A][C][G][U][G][G][C] = 2.000;
+ int22_ar[U][A][C][G][U][U][G][C] = -0.300;
+ int22_ar[U][A][C][U][A][A][G][C] = 2.000;
+ int22_ar[U][A][C][U][A][C][G][C] = 2.000;
+ int22_ar[U][A][C][U][A][G][G][C] = 2.000;
+ int22_ar[U][A][C][U][A][U][G][C] = 2.000;
+ int22_ar[U][A][C][U][C][A][G][C] = 1.500;
+ int22_ar[U][A][C][U][C][C][G][C] = 1.900;
+ int22_ar[U][A][C][U][C][G][G][C] = 2.000;
+ int22_ar[U][A][C][U][C][U][G][C] = 1.600;
+ int22_ar[U][A][C][U][G][A][G][C] = -1.100;
+ int22_ar[U][A][C][U][G][C][G][C] = 0.400;
+ int22_ar[U][A][C][U][G][G][G][C] = 2.000;
+ int22_ar[U][A][C][U][G][U][G][C] = 0.100;
+ int22_ar[U][A][C][U][U][A][G][C] = 0.700;
+ int22_ar[U][A][C][U][U][C][G][C] = 1.100;
+ int22_ar[U][A][C][U][U][G][G][C] = 2.000;
+ int22_ar[U][A][C][U][U][U][G][C] = 0.800;
+ int22_ar[U][A][G][A][A][A][G][C] = 1.100;
+ int22_ar[U][A][G][A][A][C][G][C] = 2.000;
+ int22_ar[U][A][G][A][A][G][G][C] = 1.500;
+ int22_ar[U][A][G][A][A][U][G][C] = 1.600;
+ int22_ar[U][A][G][A][C][A][G][C] = 0.800;
+ int22_ar[U][A][G][A][C][C][G][C] = 2.000;
+ int22_ar[U][A][G][A][C][G][G][C] = 1.200;
+ int22_ar[U][A][G][A][C][U][G][C] = 0.300;
+ int22_ar[U][A][G][A][G][A][G][C] = -0.900;
+ int22_ar[U][A][G][A][G][C][G][C] = 2.000;
+ int22_ar[U][A][G][A][G][G][G][C] = -0.500;
+ int22_ar[U][A][G][A][G][U][G][C] = 0.400;
+ int22_ar[U][A][G][A][U][A][G][C] = 2.000;
+ int22_ar[U][A][G][A][U][C][G][C] = 2.000;
+ int22_ar[U][A][G][A][U][G][G][C] = 2.000;
+ int22_ar[U][A][G][A][U][U][G][C] = 2.000;
+ int22_ar[U][A][G][C][A][A][G][C] = 0.800;
+ int22_ar[U][A][G][C][A][C][G][C] = 2.000;
+ int22_ar[U][A][G][C][A][G][G][C] = 1.200;
+ int22_ar[U][A][G][C][A][U][G][C] = 0.300;
+ int22_ar[U][A][G][C][C][A][G][C] = 1.800;
+ int22_ar[U][A][G][C][C][C][G][C] = 2.000;
+ int22_ar[U][A][G][C][C][G][G][C] = 1.800;
+ int22_ar[U][A][G][C][C][U][G][C] = 1.300;
+ int22_ar[U][A][G][C][G][A][G][C] = 2.000;
+ int22_ar[U][A][G][C][G][C][G][C] = 2.000;
+ int22_ar[U][A][G][C][G][G][G][C] = 2.000;
+ int22_ar[U][A][G][C][G][U][G][C] = 2.000;
+ int22_ar[U][A][G][C][U][A][G][C] = 0.900;
+ int22_ar[U][A][G][C][U][C][G][C] = 2.000;
+ int22_ar[U][A][G][C][U][G][G][C] = 0.800;
+ int22_ar[U][A][G][C][U][U][G][C] = 0.400;
+ int22_ar[U][A][G][G][A][A][G][C] = -0.300;
+ int22_ar[U][A][G][G][A][C][G][C] = 2.000;
+ int22_ar[U][A][G][G][A][G][G][C] = 0.100;
+ int22_ar[U][A][G][G][A][U][G][C] = 1.000;
+ int22_ar[U][A][G][G][C][A][G][C] = 2.000;
+ int22_ar[U][A][G][G][C][C][G][C] = 2.000;
+ int22_ar[U][A][G][G][C][G][G][C] = 2.000;
+ int22_ar[U][A][G][G][C][U][G][C] = 2.000;
+ int22_ar[U][A][G][G][G][A][G][C] = 0.700;
+ int22_ar[U][A][G][G][G][C][G][C] = 2.000;
+ int22_ar[U][A][G][G][G][G][G][C] = 1.100;
+ int22_ar[U][A][G][G][G][U][G][C] = 1.200;
+ int22_ar[U][A][G][G][U][A][G][C] = -0.300;
+ int22_ar[U][A][G][G][U][C][G][C] = 2.000;
+ int22_ar[U][A][G][G][U][G][G][C] = -0.700;
+ int22_ar[U][A][G][G][U][U][G][C] = -2.600;
+ int22_ar[U][A][G][U][A][A][G][C] = 2.000;
+ int22_ar[U][A][G][U][A][C][G][C] = 2.000;
+ int22_ar[U][A][G][U][A][G][G][C] = 2.000;
+ int22_ar[U][A][G][U][A][U][G][C] = 2.000;
+ int22_ar[U][A][G][U][C][A][G][C] = 1.900;
+ int22_ar[U][A][G][U][C][C][G][C] = 2.000;
+ int22_ar[U][A][G][U][C][G][G][C] = 1.900;
+ int22_ar[U][A][G][U][C][U][G][C] = 1.400;
+ int22_ar[U][A][G][U][G][A][G][C] = 0.100;
+ int22_ar[U][A][G][U][G][C][G][C] = 2.000;
+ int22_ar[U][A][G][U][G][G][G][C] = -0.300;
+ int22_ar[U][A][G][U][G][U][G][C] = -2.200;
+ int22_ar[U][A][G][U][U][A][G][C] = 1.900;
+ int22_ar[U][A][G][U][U][C][G][C] = 2.000;
+ int22_ar[U][A][G][U][U][G][G][C] = 1.500;
+ int22_ar[U][A][G][U][U][U][G][C] = 1.400;
+ int22_ar[U][A][U][A][A][A][G][C] = 2.000;
+ int22_ar[U][A][U][A][A][C][G][C] = 2.700;
+ int22_ar[U][A][U][A][A][G][G][C] = 0.300;
+ int22_ar[U][A][U][A][A][U][G][C] = 2.300;
+ int22_ar[U][A][U][A][C][A][G][C] = 2.000;
+ int22_ar[U][A][U][A][C][C][G][C] = 1.900;
+ int22_ar[U][A][U][A][C][G][G][C] = -0.900;
+ int22_ar[U][A][U][A][C][U][G][C] = 1.000;
+ int22_ar[U][A][U][A][G][A][G][C] = 2.000;
+ int22_ar[U][A][U][A][G][C][G][C] = 1.100;
+ int22_ar[U][A][U][A][G][G][G][C] = -0.900;
+ int22_ar[U][A][U][A][G][U][G][C] = 1.100;
+ int22_ar[U][A][U][A][U][A][G][C] = 2.000;
+ int22_ar[U][A][U][A][U][C][G][C] = 2.000;
+ int22_ar[U][A][U][A][U][G][G][C] = 2.000;
+ int22_ar[U][A][U][A][U][U][G][C] = 2.000;
+ int22_ar[U][A][U][C][A][A][G][C] = 2.000;
+ int22_ar[U][A][U][C][A][C][G][C] = 1.800;
+ int22_ar[U][A][U][C][A][G][G][C] = -1.000;
+ int22_ar[U][A][U][C][A][U][G][C] = 1.000;
+ int22_ar[U][A][U][C][C][A][G][C] = 2.000;
+ int22_ar[U][A][U][C][C][C][G][C] = 1.900;
+ int22_ar[U][A][U][C][C][G][G][C] = 0.100;
+ int22_ar[U][A][U][C][C][U][G][C] = 1.000;
+ int22_ar[U][A][U][C][G][A][G][C] = 2.000;
+ int22_ar[U][A][U][C][G][C][G][C] = 2.000;
+ int22_ar[U][A][U][C][G][G][G][C] = 2.000;
+ int22_ar[U][A][U][C][G][U][G][C] = 2.000;
+ int22_ar[U][A][U][C][U][A][G][C] = 2.000;
+ int22_ar[U][A][U][C][U][C][G][C] = 0.900;
+ int22_ar[U][A][U][C][U][G][G][C] = -0.900;
+ int22_ar[U][A][U][C][U][U][G][C] = 0.000;
+ int22_ar[U][A][U][G][A][A][G][C] = 2.000;
+ int22_ar[U][A][U][G][A][C][G][C] = 1.700;
+ int22_ar[U][A][U][G][A][G][G][C] = -0.300;
+ int22_ar[U][A][U][G][A][U][G][C] = 1.700;
+ int22_ar[U][A][U][G][C][A][G][C] = 2.000;
+ int22_ar[U][A][U][G][C][C][G][C] = 2.000;
+ int22_ar[U][A][U][G][C][G][G][C] = 2.000;
+ int22_ar[U][A][U][G][C][U][G][C] = 2.000;
+ int22_ar[U][A][U][G][G][A][G][C] = 2.000;
+ int22_ar[U][A][U][G][G][C][G][C] = 2.400;
+ int22_ar[U][A][U][G][G][G][G][C] = 0.000;
+ int22_ar[U][A][U][G][G][U][G][C] = 1.900;
+ int22_ar[U][A][U][G][U][A][G][C] = 2.000;
+ int22_ar[U][A][U][G][U][C][G][C] = 0.000;
+ int22_ar[U][A][U][G][U][G][G][C] = -3.900;
+ int22_ar[U][A][U][G][U][U][G][C] = -0.100;
+ int22_ar[U][A][U][U][A][A][G][C] = 2.000;
+ int22_ar[U][A][U][U][A][C][G][C] = 2.000;
+ int22_ar[U][A][U][U][A][G][G][C] = 2.000;
+ int22_ar[U][A][U][U][A][U][G][C] = 2.000;
+ int22_ar[U][A][U][U][C][A][G][C] = 2.000;
+ int22_ar[U][A][U][U][C][C][G][C] = 1.900;
+ int22_ar[U][A][U][U][C][G][G][C] = 0.100;
+ int22_ar[U][A][U][U][C][U][G][C] = 1.100;
+ int22_ar[U][A][U][U][G][A][G][C] = 2.000;
+ int22_ar[U][A][U][U][G][C][G][C] = 0.400;
+ int22_ar[U][A][U][U][G][G][G][C] = -3.500;
+ int22_ar[U][A][U][U][G][U][G][C] = 0.300;
+ int22_ar[U][A][U][U][U][A][G][C] = 2.000;
+ int22_ar[U][A][U][U][U][C][G][C] = 1.100;
+ int22_ar[U][A][U][U][U][G][G][C] = 0.100;
+ int22_ar[U][A][U][U][U][U][G][C] = 0.300;
+ int22_ar[U][A][A][A][A][A][G][U] = 2.800;
+ int22_ar[U][A][A][A][A][C][G][U] = 2.800;
+ int22_ar[U][A][A][A][A][G][G][U] = 1.700;
+ int22_ar[U][A][A][A][A][U][G][U] = 2.000;
+ int22_ar[U][A][A][A][C][A][G][U] = 2.500;
+ int22_ar[U][A][A][A][C][C][G][U] = 2.500;
+ int22_ar[U][A][A][A][C][G][G][U] = 1.500;
+ int22_ar[U][A][A][A][C][U][G][U] = 2.000;
+ int22_ar[U][A][A][A][G][A][G][U] = 1.500;
+ int22_ar[U][A][A][A][G][C][G][U] = 1.500;
+ int22_ar[U][A][A][A][G][G][G][U] = 0.500;
+ int22_ar[U][A][A][A][G][U][G][U] = 2.000;
+ int22_ar[U][A][A][A][U][A][G][U] = 2.000;
+ int22_ar[U][A][A][A][U][C][G][U] = 2.000;
+ int22_ar[U][A][A][A][U][G][G][U] = 2.000;
+ int22_ar[U][A][A][A][U][U][G][U] = 2.000;
+ int22_ar[U][A][A][C][A][A][G][U] = 2.600;
+ int22_ar[U][A][A][C][A][C][G][U] = 2.600;
+ int22_ar[U][A][A][C][A][G][G][U] = 1.600;
+ int22_ar[U][A][A][C][A][U][G][U] = 2.000;
+ int22_ar[U][A][A][C][C][A][G][U] = 3.100;
+ int22_ar[U][A][A][C][C][C][G][U] = 2.500;
+ int22_ar[U][A][A][C][C][G][G][U] = 2.400;
+ int22_ar[U][A][A][C][C][U][G][U] = 2.000;
+ int22_ar[U][A][A][C][G][A][G][U] = 2.000;
+ int22_ar[U][A][A][C][G][C][G][U] = 2.000;
+ int22_ar[U][A][A][C][G][G][G][U] = 2.000;
+ int22_ar[U][A][A][C][G][U][G][U] = 2.000;
+ int22_ar[U][A][A][C][U][A][G][U] = 3.100;
+ int22_ar[U][A][A][C][U][C][G][U] = 2.500;
+ int22_ar[U][A][A][C][U][G][G][U] = 2.400;
+ int22_ar[U][A][A][C][U][U][G][U] = 2.000;
+ int22_ar[U][A][A][G][A][A][G][U] = 1.500;
+ int22_ar[U][A][A][G][A][C][G][U] = 1.500;
+ int22_ar[U][A][A][G][A][G][G][U] = 0.500;
+ int22_ar[U][A][A][G][A][U][G][U] = 2.000;
+ int22_ar[U][A][A][G][C][A][G][U] = 2.000;
+ int22_ar[U][A][A][G][C][C][G][U] = 2.000;
+ int22_ar[U][A][A][G][C][G][G][U] = 2.000;
+ int22_ar[U][A][A][G][C][U][G][U] = 2.000;
+ int22_ar[U][A][A][G][G][A][G][U] = 2.100;
+ int22_ar[U][A][A][G][G][C][G][U] = 2.100;
+ int22_ar[U][A][A][G][G][G][G][U] = 1.000;
+ int22_ar[U][A][A][G][G][U][G][U] = 2.000;
+ int22_ar[U][A][A][G][U][A][G][U] = 1.300;
+ int22_ar[U][A][A][G][U][C][G][U] = 0.300;
+ int22_ar[U][A][A][G][U][G][G][U] = 1.100;
+ int22_ar[U][A][A][G][U][U][G][U] = 2.000;
+ int22_ar[U][A][A][U][A][A][G][U] = 2.000;
+ int22_ar[U][A][A][U][A][C][G][U] = 2.000;
+ int22_ar[U][A][A][U][A][G][G][U] = 2.000;
+ int22_ar[U][A][A][U][A][U][G][U] = 2.000;
+ int22_ar[U][A][A][U][C][A][G][U] = 3.100;
+ int22_ar[U][A][A][U][C][C][G][U] = 2.500;
+ int22_ar[U][A][A][U][C][G][G][U] = 2.400;
+ int22_ar[U][A][A][U][C][U][G][U] = 2.000;
+ int22_ar[U][A][A][U][G][A][G][U] = 2.300;
+ int22_ar[U][A][A][U][G][C][G][U] = 1.300;
+ int22_ar[U][A][A][U][G][G][G][U] = 2.100;
+ int22_ar[U][A][A][U][G][U][G][U] = 2.000;
+ int22_ar[U][A][A][U][U][A][G][U] = 2.700;
+ int22_ar[U][A][A][U][U][C][G][U] = 1.700;
+ int22_ar[U][A][A][U][U][G][G][U] = 2.400;
+ int22_ar[U][A][A][U][U][U][G][U] = 2.000;
+ int22_ar[U][A][C][A][A][A][G][U] = 2.300;
+ int22_ar[U][A][C][A][A][C][G][U] = 3.400;
+ int22_ar[U][A][C][A][A][G][G][U] = 2.000;
+ int22_ar[U][A][C][A][A][U][G][U] = 3.100;
+ int22_ar[U][A][C][A][C][A][G][U] = 2.100;
+ int22_ar[U][A][C][A][C][C][G][U] = 2.500;
+ int22_ar[U][A][C][A][C][G][G][U] = 2.000;
+ int22_ar[U][A][C][A][C][U][G][U] = 2.200;
+ int22_ar[U][A][C][A][G][A][G][U] = 1.100;
+ int22_ar[U][A][C][A][G][C][G][U] = 2.500;
+ int22_ar[U][A][C][A][G][G][G][U] = 2.000;
+ int22_ar[U][A][C][A][G][U][G][U] = 2.200;
+ int22_ar[U][A][C][A][U][A][G][U] = 2.000;
+ int22_ar[U][A][C][A][U][C][G][U] = 2.000;
+ int22_ar[U][A][C][A][U][G][G][U] = 2.000;
+ int22_ar[U][A][C][A][U][U][G][U] = 2.000;
+ int22_ar[U][A][C][C][A][A][G][U] = 2.200;
+ int22_ar[U][A][C][C][A][C][G][U] = 2.600;
+ int22_ar[U][A][C][C][A][G][G][U] = 2.000;
+ int22_ar[U][A][C][C][A][U][G][U] = 2.300;
+ int22_ar[U][A][C][C][C][A][G][U] = 2.000;
+ int22_ar[U][A][C][C][C][C][G][U] = 2.500;
+ int22_ar[U][A][C][C][C][G][G][U] = 2.000;
+ int22_ar[U][A][C][C][C][U][G][U] = 2.200;
+ int22_ar[U][A][C][C][G][A][G][U] = 2.000;
+ int22_ar[U][A][C][C][G][C][G][U] = 2.000;
+ int22_ar[U][A][C][C][G][G][G][U] = 2.000;
+ int22_ar[U][A][C][C][G][U][G][U] = 2.000;
+ int22_ar[U][A][C][C][U][A][G][U] = 2.000;
+ int22_ar[U][A][C][C][U][C][G][U] = 2.500;
+ int22_ar[U][A][C][C][U][G][G][U] = 2.000;
+ int22_ar[U][A][C][C][U][U][G][U] = 2.200;
+ int22_ar[U][A][C][G][A][A][G][U] = 1.100;
+ int22_ar[U][A][C][G][A][C][G][U] = 2.500;
+ int22_ar[U][A][C][G][A][G][G][U] = 2.000;
+ int22_ar[U][A][C][G][A][U][G][U] = 2.200;
+ int22_ar[U][A][C][G][C][A][G][U] = 2.000;
+ int22_ar[U][A][C][G][C][C][G][U] = 2.000;
+ int22_ar[U][A][C][G][C][G][G][U] = 2.000;
+ int22_ar[U][A][C][G][C][U][G][U] = 2.000;
+ int22_ar[U][A][C][G][G][A][G][U] = 1.600;
+ int22_ar[U][A][C][G][G][C][G][U] = 2.700;
+ int22_ar[U][A][C][G][G][G][G][U] = 2.000;
+ int22_ar[U][A][C][G][G][U][G][U] = 2.400;
+ int22_ar[U][A][C][G][U][A][G][U] = -0.100;
+ int22_ar[U][A][C][G][U][C][G][U] = 1.300;
+ int22_ar[U][A][C][G][U][G][G][U] = 2.000;
+ int22_ar[U][A][C][G][U][U][G][U] = 1.000;
+ int22_ar[U][A][C][U][A][A][G][U] = 2.000;
+ int22_ar[U][A][C][U][A][C][G][U] = 2.000;
+ int22_ar[U][A][C][U][A][G][G][U] = 2.000;
+ int22_ar[U][A][C][U][A][U][G][U] = 2.000;
+ int22_ar[U][A][C][U][C][A][G][U] = 2.000;
+ int22_ar[U][A][C][U][C][C][G][U] = 2.500;
+ int22_ar[U][A][C][U][C][G][G][U] = 2.000;
+ int22_ar[U][A][C][U][C][U][G][U] = 2.200;
+ int22_ar[U][A][C][U][G][A][G][U] = 0.900;
+ int22_ar[U][A][C][U][G][C][G][U] = 2.300;
+ int22_ar[U][A][C][U][G][G][G][U] = 2.000;
+ int22_ar[U][A][C][U][G][U][G][U] = 2.000;
+ int22_ar[U][A][C][U][U][A][G][U] = 1.200;
+ int22_ar[U][A][C][U][U][C][G][U] = 1.700;
+ int22_ar[U][A][C][U][U][G][G][U] = 2.000;
+ int22_ar[U][A][C][U][U][U][G][U] = 1.400;
+ int22_ar[U][A][G][A][A][A][G][U] = 1.700;
+ int22_ar[U][A][G][A][A][C][G][U] = 2.000;
+ int22_ar[U][A][G][A][A][G][G][U] = 2.100;
+ int22_ar[U][A][G][A][A][U][G][U] = 2.200;
+ int22_ar[U][A][G][A][C][A][G][U] = 1.500;
+ int22_ar[U][A][G][A][C][C][G][U] = 2.000;
+ int22_ar[U][A][G][A][C][G][G][U] = 1.900;
+ int22_ar[U][A][G][A][C][U][G][U] = 1.000;
+ int22_ar[U][A][G][A][G][A][G][U] = 0.500;
+ int22_ar[U][A][G][A][G][C][G][U] = 2.000;
+ int22_ar[U][A][G][A][G][G][G][U] = 0.900;
+ int22_ar[U][A][G][A][G][U][G][U] = 1.800;
+ int22_ar[U][A][G][A][U][A][G][U] = 2.000;
+ int22_ar[U][A][G][A][U][C][G][U] = 2.000;
+ int22_ar[U][A][G][A][U][G][G][U] = 2.000;
+ int22_ar[U][A][G][A][U][U][G][U] = 2.000;
+ int22_ar[U][A][G][C][A][A][G][U] = 1.600;
+ int22_ar[U][A][G][C][A][C][G][U] = 2.000;
+ int22_ar[U][A][G][C][A][G][G][U] = 2.000;
+ int22_ar[U][A][G][C][A][U][G][U] = 1.100;
+ int22_ar[U][A][G][C][C][A][G][U] = 2.400;
+ int22_ar[U][A][G][C][C][C][G][U] = 2.000;
+ int22_ar[U][A][G][C][C][G][G][U] = 2.400;
+ int22_ar[U][A][G][C][C][U][G][U] = 1.900;
+ int22_ar[U][A][G][C][G][A][G][U] = 2.000;
+ int22_ar[U][A][G][C][G][C][G][U] = 2.000;
+ int22_ar[U][A][G][C][G][G][G][U] = 2.000;
+ int22_ar[U][A][G][C][G][U][G][U] = 2.000;
+ int22_ar[U][A][G][C][U][A][G][U] = 2.400;
+ int22_ar[U][A][G][C][U][C][G][U] = 2.000;
+ int22_ar[U][A][G][C][U][G][G][U] = 2.400;
+ int22_ar[U][A][G][C][U][U][G][U] = 1.900;
+ int22_ar[U][A][G][G][A][A][G][U] = 0.500;
+ int22_ar[U][A][G][G][A][C][G][U] = 2.000;
+ int22_ar[U][A][G][G][A][G][G][U] = 0.900;
+ int22_ar[U][A][G][G][A][U][G][U] = 1.800;
+ int22_ar[U][A][G][G][C][A][G][U] = 2.000;
+ int22_ar[U][A][G][G][C][C][G][U] = 2.000;
+ int22_ar[U][A][G][G][C][G][G][U] = 2.000;
+ int22_ar[U][A][G][G][C][U][G][U] = 2.000;
+ int22_ar[U][A][G][G][G][A][G][U] = 1.000;
+ int22_ar[U][A][G][G][G][C][G][U] = 2.000;
+ int22_ar[U][A][G][G][G][G][G][U] = 1.400;
+ int22_ar[U][A][G][G][G][U][G][U] = 1.500;
+ int22_ar[U][A][G][G][U][A][G][U] = 1.100;
+ int22_ar[U][A][G][G][U][C][G][U] = 2.000;
+ int22_ar[U][A][G][G][U][G][G][U] = 0.700;
+ int22_ar[U][A][G][G][U][U][G][U] = -1.200;
+ int22_ar[U][A][G][U][A][A][G][U] = 2.000;
+ int22_ar[U][A][G][U][A][C][G][U] = 2.000;
+ int22_ar[U][A][G][U][A][G][G][U] = 2.000;
+ int22_ar[U][A][G][U][A][U][G][U] = 2.000;
+ int22_ar[U][A][G][U][C][A][G][U] = 2.400;
+ int22_ar[U][A][G][U][C][C][G][U] = 2.000;
+ int22_ar[U][A][G][U][C][G][G][U] = 2.400;
+ int22_ar[U][A][G][U][C][U][G][U] = 1.900;
+ int22_ar[U][A][G][U][G][A][G][U] = 2.100;
+ int22_ar[U][A][G][U][G][C][G][U] = 2.000;
+ int22_ar[U][A][G][U][G][G][G][U] = 1.700;
+ int22_ar[U][A][G][U][G][U][G][U] = -0.200;
+ int22_ar[U][A][G][U][U][A][G][U] = 2.400;
+ int22_ar[U][A][G][U][U][C][G][U] = 2.000;
+ int22_ar[U][A][G][U][U][G][G][U] = 2.000;
+ int22_ar[U][A][G][U][U][U][G][U] = 1.900;
+ int22_ar[U][A][U][A][A][A][G][U] = 2.000;
+ int22_ar[U][A][U][A][A][C][G][U] = 3.400;
+ int22_ar[U][A][U][A][A][G][G][U] = 1.000;
+ int22_ar[U][A][U][A][A][U][G][U] = 2.900;
+ int22_ar[U][A][U][A][C][A][G][U] = 2.000;
+ int22_ar[U][A][U][A][C][C][G][U] = 2.500;
+ int22_ar[U][A][U][A][C][G][G][U] = -0.300;
+ int22_ar[U][A][U][A][C][U][G][U] = 1.700;
+ int22_ar[U][A][U][A][G][A][G][U] = 2.000;
+ int22_ar[U][A][U][A][G][C][G][U] = 2.500;
+ int22_ar[U][A][U][A][G][G][G][U] = 0.500;
+ int22_ar[U][A][U][A][G][U][G][U] = 2.500;
+ int22_ar[U][A][U][A][U][A][G][U] = 2.000;
+ int22_ar[U][A][U][A][U][C][G][U] = 2.000;
+ int22_ar[U][A][U][A][U][G][G][U] = 2.000;
+ int22_ar[U][A][U][A][U][U][G][U] = 2.000;
+ int22_ar[U][A][U][C][A][A][G][U] = 2.000;
+ int22_ar[U][A][U][C][A][C][G][U] = 2.600;
+ int22_ar[U][A][U][C][A][G][G][U] = -0.200;
+ int22_ar[U][A][U][C][A][U][G][U] = 1.800;
+ int22_ar[U][A][U][C][C][A][G][U] = 2.000;
+ int22_ar[U][A][U][C][C][C][G][U] = 2.500;
+ int22_ar[U][A][U][C][C][G][G][U] = 0.700;
+ int22_ar[U][A][U][C][C][U][G][U] = 1.600;
+ int22_ar[U][A][U][C][G][A][G][U] = 2.000;
+ int22_ar[U][A][U][C][G][C][G][U] = 2.000;
+ int22_ar[U][A][U][C][G][G][G][U] = 2.000;
+ int22_ar[U][A][U][C][G][U][G][U] = 2.000;
+ int22_ar[U][A][U][C][U][A][G][U] = 2.000;
+ int22_ar[U][A][U][C][U][C][G][U] = 2.500;
+ int22_ar[U][A][U][C][U][G][G][U] = 0.700;
+ int22_ar[U][A][U][C][U][U][G][U] = 1.600;
+ int22_ar[U][A][U][G][A][A][G][U] = 2.000;
+ int22_ar[U][A][U][G][A][C][G][U] = 2.500;
+ int22_ar[U][A][U][G][A][G][G][U] = 0.500;
+ int22_ar[U][A][U][G][A][U][G][U] = 2.500;
+ int22_ar[U][A][U][G][C][A][G][U] = 2.000;
+ int22_ar[U][A][U][G][C][C][G][U] = 2.000;
+ int22_ar[U][A][U][G][C][G][G][U] = 2.000;
+ int22_ar[U][A][U][G][C][U][G][U] = 2.000;
+ int22_ar[U][A][U][G][G][A][G][U] = 2.000;
+ int22_ar[U][A][U][G][G][C][G][U] = 2.700;
+ int22_ar[U][A][U][G][G][G][G][U] = 0.300;
+ int22_ar[U][A][U][G][G][U][G][U] = 2.200;
+ int22_ar[U][A][U][G][U][A][G][U] = 2.000;
+ int22_ar[U][A][U][G][U][C][G][U] = 1.300;
+ int22_ar[U][A][U][G][U][G][G][U] = -2.500;
+ int22_ar[U][A][U][G][U][U][G][U] = 1.300;
+ int22_ar[U][A][U][U][A][A][G][U] = 2.000;
+ int22_ar[U][A][U][U][A][C][G][U] = 2.000;
+ int22_ar[U][A][U][U][A][G][G][U] = 2.000;
+ int22_ar[U][A][U][U][A][U][G][U] = 2.000;
+ int22_ar[U][A][U][U][C][A][G][U] = 2.000;
+ int22_ar[U][A][U][U][C][C][G][U] = 2.500;
+ int22_ar[U][A][U][U][C][G][G][U] = 0.700;
+ int22_ar[U][A][U][U][C][U][G][U] = 1.600;
+ int22_ar[U][A][U][U][G][A][G][U] = 2.000;
+ int22_ar[U][A][U][U][G][C][G][U] = 2.300;
+ int22_ar[U][A][U][U][G][G][G][U] = -1.500;
+ int22_ar[U][A][U][U][G][U][G][U] = 2.300;
+ int22_ar[U][A][U][U][U][A][G][U] = 2.000;
+ int22_ar[U][A][U][U][U][C][G][U] = 1.700;
+ int22_ar[U][A][U][U][U][G][G][U] = 0.700;
+ int22_ar[U][A][U][U][U][U][G][U] = 0.800;
+ int22_ar[U][A][A][A][A][A][U][A] = 2.800;
+ int22_ar[U][A][A][A][A][C][U][A] = 2.800;
+ int22_ar[U][A][A][A][A][G][U][A] = 1.700;
+ int22_ar[U][A][A][A][A][U][U][A] = 2.000;
+ int22_ar[U][A][A][A][C][A][U][A] = 2.300;
+ int22_ar[U][A][A][A][C][C][U][A] = 2.300;
+ int22_ar[U][A][A][A][C][G][U][A] = 1.300;
+ int22_ar[U][A][A][A][C][U][U][A] = 2.000;
+ int22_ar[U][A][A][A][G][A][U][A] = 1.700;
+ int22_ar[U][A][A][A][G][C][U][A] = 1.700;
+ int22_ar[U][A][A][A][G][G][U][A] = 0.700;
+ int22_ar[U][A][A][A][G][U][U][A] = 2.000;
+ int22_ar[U][A][A][A][U][A][U][A] = 2.000;
+ int22_ar[U][A][A][A][U][C][U][A] = 2.000;
+ int22_ar[U][A][A][A][U][G][U][A] = 2.000;
+ int22_ar[U][A][A][A][U][U][U][A] = 2.000;
+ int22_ar[U][A][A][C][A][A][U][A] = 2.800;
+ int22_ar[U][A][A][C][A][C][U][A] = 2.800;
+ int22_ar[U][A][A][C][A][G][U][A] = 1.700;
+ int22_ar[U][A][A][C][A][U][U][A] = 2.000;
+ int22_ar[U][A][A][C][C][A][U][A] = 3.400;
+ int22_ar[U][A][A][C][C][C][U][A] = 2.800;
+ int22_ar[U][A][A][C][C][G][U][A] = 2.700;
+ int22_ar[U][A][A][C][C][U][U][A] = 2.000;
+ int22_ar[U][A][A][C][G][A][U][A] = 2.000;
+ int22_ar[U][A][A][C][G][C][U][A] = 2.000;
+ int22_ar[U][A][A][C][G][G][U][A] = 2.000;
+ int22_ar[U][A][A][C][G][U][U][A] = 2.000;
+ int22_ar[U][A][A][C][U][A][U][A] = 3.400;
+ int22_ar[U][A][A][C][U][C][U][A] = 2.800;
+ int22_ar[U][A][A][C][U][G][U][A] = 2.700;
+ int22_ar[U][A][A][C][U][U][U][A] = 2.000;
+ int22_ar[U][A][A][G][A][A][U][A] = 1.700;
+ int22_ar[U][A][A][G][A][C][U][A] = 1.700;
+ int22_ar[U][A][A][G][A][G][U][A] = 0.700;
+ int22_ar[U][A][A][G][A][U][U][A] = 2.000;
+ int22_ar[U][A][A][G][C][A][U][A] = 2.000;
+ int22_ar[U][A][A][G][C][C][U][A] = 2.000;
+ int22_ar[U][A][A][G][C][G][U][A] = 2.000;
+ int22_ar[U][A][A][G][C][U][U][A] = 2.000;
+ int22_ar[U][A][A][G][G][A][U][A] = 2.100;
+ int22_ar[U][A][A][G][G][C][U][A] = 2.100;
+ int22_ar[U][A][A][G][G][G][U][A] = 1.100;
+ int22_ar[U][A][A][G][G][U][U][A] = 2.000;
+ int22_ar[U][A][A][G][U][A][U][A] = 1.000;
+ int22_ar[U][A][A][G][U][C][U][A] = 0.000;
+ int22_ar[U][A][A][G][U][G][U][A] = 0.700;
+ int22_ar[U][A][A][G][U][U][U][A] = 2.000;
+ int22_ar[U][A][A][U][A][A][U][A] = 2.000;
+ int22_ar[U][A][A][U][A][C][U][A] = 2.000;
+ int22_ar[U][A][A][U][A][G][U][A] = 2.000;
+ int22_ar[U][A][A][U][A][U][U][A] = 2.000;
+ int22_ar[U][A][A][U][C][A][U][A] = 3.100;
+ int22_ar[U][A][A][U][C][C][U][A] = 2.500;
+ int22_ar[U][A][A][U][C][G][U][A] = 2.400;
+ int22_ar[U][A][A][U][C][U][U][A] = 2.000;
+ int22_ar[U][A][A][U][G][A][U][A] = 2.200;
+ int22_ar[U][A][A][U][G][C][U][A] = 1.200;
+ int22_ar[U][A][A][U][G][G][U][A] = 2.000;
+ int22_ar[U][A][A][U][G][U][U][A] = 2.000;
+ int22_ar[U][A][A][U][U][A][U][A] = 2.900;
+ int22_ar[U][A][A][U][U][C][U][A] = 1.900;
+ int22_ar[U][A][A][U][U][G][U][A] = 2.700;
+ int22_ar[U][A][A][U][U][U][U][A] = 2.000;
+ int22_ar[U][A][C][A][A][A][U][A] = 2.300;
+ int22_ar[U][A][C][A][A][C][U][A] = 3.400;
+ int22_ar[U][A][C][A][A][G][U][A] = 2.000;
+ int22_ar[U][A][C][A][A][U][U][A] = 3.100;
+ int22_ar[U][A][C][A][C][A][U][A] = 1.900;
+ int22_ar[U][A][C][A][C][C][U][A] = 2.300;
+ int22_ar[U][A][C][A][C][G][U][A] = 2.000;
+ int22_ar[U][A][C][A][C][U][U][A] = 2.000;
+ int22_ar[U][A][C][A][G][A][U][A] = 1.300;
+ int22_ar[U][A][C][A][G][C][U][A] = 2.700;
+ int22_ar[U][A][C][A][G][G][U][A] = 2.000;
+ int22_ar[U][A][C][A][G][U][U][A] = 2.400;
+ int22_ar[U][A][C][A][U][A][U][A] = 2.000;
+ int22_ar[U][A][C][A][U][C][U][A] = 2.000;
+ int22_ar[U][A][C][A][U][G][U][A] = 2.000;
+ int22_ar[U][A][C][A][U][U][U][A] = 2.000;
+ int22_ar[U][A][C][C][A][A][U][A] = 2.300;
+ int22_ar[U][A][C][C][A][C][U][A] = 2.800;
+ int22_ar[U][A][C][C][A][G][U][A] = 2.000;
+ int22_ar[U][A][C][C][A][U][U][A] = 2.500;
+ int22_ar[U][A][C][C][C][A][U][A] = 2.300;
+ int22_ar[U][A][C][C][C][C][U][A] = 2.800;
+ int22_ar[U][A][C][C][C][G][U][A] = 2.000;
+ int22_ar[U][A][C][C][C][U][U][A] = 2.500;
+ int22_ar[U][A][C][C][G][A][U][A] = 2.000;
+ int22_ar[U][A][C][C][G][C][U][A] = 2.000;
+ int22_ar[U][A][C][C][G][G][U][A] = 2.000;
+ int22_ar[U][A][C][C][G][U][U][A] = 2.000;
+ int22_ar[U][A][C][C][U][A][U][A] = 2.300;
+ int22_ar[U][A][C][C][U][C][U][A] = 2.800;
+ int22_ar[U][A][C][C][U][G][U][A] = 2.000;
+ int22_ar[U][A][C][C][U][U][U][A] = 2.500;
+ int22_ar[U][A][C][G][A][A][U][A] = 1.300;
+ int22_ar[U][A][C][G][A][C][U][A] = 2.700;
+ int22_ar[U][A][C][G][A][G][U][A] = 2.000;
+ int22_ar[U][A][C][G][A][U][U][A] = 2.400;
+ int22_ar[U][A][C][G][C][A][U][A] = 2.000;
+ int22_ar[U][A][C][G][C][C][U][A] = 2.000;
+ int22_ar[U][A][C][G][C][G][U][A] = 2.000;
+ int22_ar[U][A][C][G][C][U][U][A] = 2.000;
+ int22_ar[U][A][C][G][G][A][U][A] = 1.700;
+ int22_ar[U][A][C][G][G][C][U][A] = 2.700;
+ int22_ar[U][A][C][G][G][G][U][A] = 2.000;
+ int22_ar[U][A][C][G][G][U][U][A] = 2.400;
+ int22_ar[U][A][C][G][U][A][U][A] = -0.500;
+ int22_ar[U][A][C][G][U][C][U][A] = 1.000;
+ int22_ar[U][A][C][G][U][G][U][A] = 2.000;
+ int22_ar[U][A][C][G][U][U][U][A] = 0.700;
+ int22_ar[U][A][C][U][A][A][U][A] = 2.000;
+ int22_ar[U][A][C][U][A][C][U][A] = 2.000;
+ int22_ar[U][A][C][U][A][G][U][A] = 2.000;
+ int22_ar[U][A][C][U][A][U][U][A] = 2.000;
+ int22_ar[U][A][C][U][C][A][U][A] = 2.000;
+ int22_ar[U][A][C][U][C][C][U][A] = 2.500;
+ int22_ar[U][A][C][U][C][G][U][A] = 2.000;
+ int22_ar[U][A][C][U][C][U][U][A] = 2.200;
+ int22_ar[U][A][C][U][G][A][U][A] = 0.800;
+ int22_ar[U][A][C][U][G][C][U][A] = 2.200;
+ int22_ar[U][A][C][U][G][G][U][A] = 2.000;
+ int22_ar[U][A][C][U][G][U][U][A] = 1.900;
+ int22_ar[U][A][C][U][U][A][U][A] = 1.500;
+ int22_ar[U][A][C][U][U][C][U][A] = 1.900;
+ int22_ar[U][A][C][U][U][G][U][A] = 2.000;
+ int22_ar[U][A][C][U][U][U][U][A] = 1.600;
+ int22_ar[U][A][G][A][A][A][U][A] = 1.700;
+ int22_ar[U][A][G][A][A][C][U][A] = 2.000;
+ int22_ar[U][A][G][A][A][G][U][A] = 2.100;
+ int22_ar[U][A][G][A][A][U][U][A] = 2.200;
+ int22_ar[U][A][G][A][C][A][U][A] = 1.300;
+ int22_ar[U][A][G][A][C][C][U][A] = 2.000;
+ int22_ar[U][A][G][A][C][G][U][A] = 1.700;
+ int22_ar[U][A][G][A][C][U][U][A] = 0.800;
+ int22_ar[U][A][G][A][G][A][U][A] = 0.700;
+ int22_ar[U][A][G][A][G][C][U][A] = 2.000;
+ int22_ar[U][A][G][A][G][G][U][A] = 1.100;
+ int22_ar[U][A][G][A][G][U][U][A] = 2.000;
+ int22_ar[U][A][G][A][U][A][U][A] = 2.000;
+ int22_ar[U][A][G][A][U][C][U][A] = 2.000;
+ int22_ar[U][A][G][A][U][G][U][A] = 2.000;
+ int22_ar[U][A][G][A][U][U][U][A] = 2.000;
+ int22_ar[U][A][G][C][A][A][U][A] = 1.700;
+ int22_ar[U][A][G][C][A][C][U][A] = 2.000;
+ int22_ar[U][A][G][C][A][G][U][A] = 2.100;
+ int22_ar[U][A][G][C][A][U][U][A] = 1.200;
+ int22_ar[U][A][G][C][C][A][U][A] = 2.700;
+ int22_ar[U][A][G][C][C][C][U][A] = 2.000;
+ int22_ar[U][A][G][C][C][G][U][A] = 2.700;
+ int22_ar[U][A][G][C][C][U][U][A] = 2.200;
+ int22_ar[U][A][G][C][G][A][U][A] = 2.000;
+ int22_ar[U][A][G][C][G][C][U][A] = 2.000;
+ int22_ar[U][A][G][C][G][G][U][A] = 2.000;
+ int22_ar[U][A][G][C][G][U][U][A] = 2.000;
+ int22_ar[U][A][G][C][U][A][U][A] = 2.700;
+ int22_ar[U][A][G][C][U][C][U][A] = 2.000;
+ int22_ar[U][A][G][C][U][G][U][A] = 2.700;
+ int22_ar[U][A][G][C][U][U][U][A] = 2.200;
+ int22_ar[U][A][G][G][A][A][U][A] = 0.700;
+ int22_ar[U][A][G][G][A][C][U][A] = 2.000;
+ int22_ar[U][A][G][G][A][G][U][A] = 1.100;
+ int22_ar[U][A][G][G][A][U][U][A] = 2.000;
+ int22_ar[U][A][G][G][C][A][U][A] = 2.000;
+ int22_ar[U][A][G][G][C][C][U][A] = 2.000;
+ int22_ar[U][A][G][G][C][G][U][A] = 2.000;
+ int22_ar[U][A][G][G][C][U][U][A] = 2.000;
+ int22_ar[U][A][G][G][G][A][U][A] = 1.100;
+ int22_ar[U][A][G][G][G][C][U][A] = 2.000;
+ int22_ar[U][A][G][G][G][G][U][A] = 1.500;
+ int22_ar[U][A][G][G][G][U][U][A] = 1.600;
+ int22_ar[U][A][G][G][U][A][U][A] = 0.700;
+ int22_ar[U][A][G][G][U][C][U][A] = 2.000;
+ int22_ar[U][A][G][G][U][G][U][A] = 0.300;
+ int22_ar[U][A][G][G][U][U][U][A] = -1.600;
+ int22_ar[U][A][G][U][A][A][U][A] = 2.000;
+ int22_ar[U][A][G][U][A][C][U][A] = 2.000;
+ int22_ar[U][A][G][U][A][G][U][A] = 2.000;
+ int22_ar[U][A][G][U][A][U][U][A] = 2.000;
+ int22_ar[U][A][G][U][C][A][U][A] = 2.400;
+ int22_ar[U][A][G][U][C][C][U][A] = 2.000;
+ int22_ar[U][A][G][U][C][G][U][A] = 2.400;
+ int22_ar[U][A][G][U][C][U][U][A] = 1.900;
+ int22_ar[U][A][G][U][G][A][U][A] = 2.000;
+ int22_ar[U][A][G][U][G][C][U][A] = 2.000;
+ int22_ar[U][A][G][U][G][G][U][A] = 1.600;
+ int22_ar[U][A][G][U][G][U][U][A] = -0.300;
+ int22_ar[U][A][G][U][U][A][U][A] = 2.700;
+ int22_ar[U][A][G][U][U][C][U][A] = 2.000;
+ int22_ar[U][A][G][U][U][G][U][A] = 2.300;
+ int22_ar[U][A][G][U][U][U][U][A] = 2.200;
+ int22_ar[U][A][U][A][A][A][U][A] = 2.000;
+ int22_ar[U][A][U][A][A][C][U][A] = 3.400;
+ int22_ar[U][A][U][A][A][G][U][A] = 1.000;
+ int22_ar[U][A][U][A][A][U][U][A] = 2.900;
+ int22_ar[U][A][U][A][C][A][U][A] = 2.000;
+ int22_ar[U][A][U][A][C][C][U][A] = 2.300;
+ int22_ar[U][A][U][A][C][G][U][A] = -0.500;
+ int22_ar[U][A][U][A][C][U][U][A] = 1.500;
+ int22_ar[U][A][U][A][G][A][U][A] = 2.000;
+ int22_ar[U][A][U][A][G][C][U][A] = 2.700;
+ int22_ar[U][A][U][A][G][G][U][A] = 0.700;
+ int22_ar[U][A][U][A][G][U][U][A] = 2.700;
+ int22_ar[U][A][U][A][U][A][U][A] = 2.000;
+ int22_ar[U][A][U][A][U][C][U][A] = 2.000;
+ int22_ar[U][A][U][A][U][G][U][A] = 2.000;
+ int22_ar[U][A][U][A][U][U][U][A] = 2.000;
+ int22_ar[U][A][U][C][A][A][U][A] = 2.000;
+ int22_ar[U][A][U][C][A][C][U][A] = 2.800;
+ int22_ar[U][A][U][C][A][G][U][A] = 0.000;
+ int22_ar[U][A][U][C][A][U][U][A] = 1.900;
+ int22_ar[U][A][U][C][C][A][U][A] = 2.000;
+ int22_ar[U][A][U][C][C][C][U][A] = 2.800;
+ int22_ar[U][A][U][C][C][G][U][A] = 1.000;
+ int22_ar[U][A][U][C][C][U][U][A] = 1.900;
+ int22_ar[U][A][U][C][G][A][U][A] = 2.000;
+ int22_ar[U][A][U][C][G][C][U][A] = 2.000;
+ int22_ar[U][A][U][C][G][G][U][A] = 2.000;
+ int22_ar[U][A][U][C][G][U][U][A] = 2.000;
+ int22_ar[U][A][U][C][U][A][U][A] = 2.000;
+ int22_ar[U][A][U][C][U][C][U][A] = 2.800;
+ int22_ar[U][A][U][C][U][G][U][A] = 1.000;
+ int22_ar[U][A][U][C][U][U][U][A] = 1.900;
+ int22_ar[U][A][U][G][A][A][U][A] = 2.000;
+ int22_ar[U][A][U][G][A][C][U][A] = 2.700;
+ int22_ar[U][A][U][G][A][G][U][A] = 0.700;
+ int22_ar[U][A][U][G][A][U][U][A] = 2.700;
+ int22_ar[U][A][U][G][C][A][U][A] = 2.000;
+ int22_ar[U][A][U][G][C][C][U][A] = 2.000;
+ int22_ar[U][A][U][G][C][G][U][A] = 2.000;
+ int22_ar[U][A][U][G][C][U][U][A] = 2.000;
+ int22_ar[U][A][U][G][G][A][U][A] = 2.000;
+ int22_ar[U][A][U][G][G][C][U][A] = 2.700;
+ int22_ar[U][A][U][G][G][G][U][A] = 0.300;
+ int22_ar[U][A][U][G][G][U][U][A] = 2.300;
+ int22_ar[U][A][U][G][U][A][U][A] = 2.000;
+ int22_ar[U][A][U][G][U][C][U][A] = 1.000;
+ int22_ar[U][A][U][G][U][G][U][A] = -2.900;
+ int22_ar[U][A][U][G][U][U][U][A] = 0.900;
+ int22_ar[U][A][U][U][A][A][U][A] = 2.000;
+ int22_ar[U][A][U][U][A][C][U][A] = 2.000;
+ int22_ar[U][A][U][U][A][G][U][A] = 2.000;
+ int22_ar[U][A][U][U][A][U][U][A] = 2.000;
+ int22_ar[U][A][U][U][C][A][U][A] = 2.000;
+ int22_ar[U][A][U][U][C][C][U][A] = 2.500;
+ int22_ar[U][A][U][U][C][G][U][A] = 0.700;
+ int22_ar[U][A][U][U][C][U][U][A] = 1.600;
+ int22_ar[U][A][U][U][G][A][U][A] = 2.000;
+ int22_ar[U][A][U][U][G][C][U][A] = 2.200;
+ int22_ar[U][A][U][U][G][G][U][A] = -1.600;
+ int22_ar[U][A][U][U][G][U][U][A] = 2.200;
+ int22_ar[U][A][U][U][U][A][U][A] = 2.000;
+ int22_ar[U][A][U][U][U][C][U][A] = 1.900;
+ int22_ar[U][A][U][U][U][G][U][A] = 0.900;
+ int22_ar[U][A][U][U][U][U][U][A] = 1.100;
+ int22_ar[U][A][A][A][A][A][U][G] = 2.800;
+ int22_ar[U][A][A][A][A][C][U][G] = 2.800;
+ int22_ar[U][A][A][A][A][G][U][G] = 1.700;
+ int22_ar[U][A][A][A][A][U][U][G] = 2.000;
+ int22_ar[U][A][A][A][C][A][U][G] = 2.300;
+ int22_ar[U][A][A][A][C][C][U][G] = 2.300;
+ int22_ar[U][A][A][A][C][G][U][G] = 1.300;
+ int22_ar[U][A][A][A][C][U][U][G] = 2.000;
+ int22_ar[U][A][A][A][G][A][U][G] = 1.700;
+ int22_ar[U][A][A][A][G][C][U][G] = 1.700;
+ int22_ar[U][A][A][A][G][G][U][G] = 0.700;
+ int22_ar[U][A][A][A][G][U][U][G] = 2.000;
+ int22_ar[U][A][A][A][U][A][U][G] = 2.000;
+ int22_ar[U][A][A][A][U][C][U][G] = 2.000;
+ int22_ar[U][A][A][A][U][G][U][G] = 2.000;
+ int22_ar[U][A][A][A][U][U][U][G] = 2.000;
+ int22_ar[U][A][A][C][A][A][U][G] = 2.800;
+ int22_ar[U][A][A][C][A][C][U][G] = 2.800;
+ int22_ar[U][A][A][C][A][G][U][G] = 1.700;
+ int22_ar[U][A][A][C][A][U][U][G] = 2.000;
+ int22_ar[U][A][A][C][C][A][U][G] = 3.400;
+ int22_ar[U][A][A][C][C][C][U][G] = 2.800;
+ int22_ar[U][A][A][C][C][G][U][G] = 2.700;
+ int22_ar[U][A][A][C][C][U][U][G] = 2.000;
+ int22_ar[U][A][A][C][G][A][U][G] = 2.000;
+ int22_ar[U][A][A][C][G][C][U][G] = 2.000;
+ int22_ar[U][A][A][C][G][G][U][G] = 2.000;
+ int22_ar[U][A][A][C][G][U][U][G] = 2.000;
+ int22_ar[U][A][A][C][U][A][U][G] = 3.400;
+ int22_ar[U][A][A][C][U][C][U][G] = 2.800;
+ int22_ar[U][A][A][C][U][G][U][G] = 2.700;
+ int22_ar[U][A][A][C][U][U][U][G] = 2.000;
+ int22_ar[U][A][A][G][A][A][U][G] = 1.700;
+ int22_ar[U][A][A][G][A][C][U][G] = 1.700;
+ int22_ar[U][A][A][G][A][G][U][G] = 0.700;
+ int22_ar[U][A][A][G][A][U][U][G] = 2.000;
+ int22_ar[U][A][A][G][C][A][U][G] = 2.000;
+ int22_ar[U][A][A][G][C][C][U][G] = 2.000;
+ int22_ar[U][A][A][G][C][G][U][G] = 2.000;
+ int22_ar[U][A][A][G][C][U][U][G] = 2.000;
+ int22_ar[U][A][A][G][G][A][U][G] = 2.100;
+ int22_ar[U][A][A][G][G][C][U][G] = 2.100;
+ int22_ar[U][A][A][G][G][G][U][G] = 1.100;
+ int22_ar[U][A][A][G][G][U][U][G] = 2.000;
+ int22_ar[U][A][A][G][U][A][U][G] = 1.000;
+ int22_ar[U][A][A][G][U][C][U][G] = 0.000;
+ int22_ar[U][A][A][G][U][G][U][G] = 0.700;
+ int22_ar[U][A][A][G][U][U][U][G] = 2.000;
+ int22_ar[U][A][A][U][A][A][U][G] = 2.000;
+ int22_ar[U][A][A][U][A][C][U][G] = 2.000;
+ int22_ar[U][A][A][U][A][G][U][G] = 2.000;
+ int22_ar[U][A][A][U][A][U][U][G] = 2.000;
+ int22_ar[U][A][A][U][C][A][U][G] = 3.100;
+ int22_ar[U][A][A][U][C][C][U][G] = 2.500;
+ int22_ar[U][A][A][U][C][G][U][G] = 2.400;
+ int22_ar[U][A][A][U][C][U][U][G] = 2.000;
+ int22_ar[U][A][A][U][G][A][U][G] = 2.200;
+ int22_ar[U][A][A][U][G][C][U][G] = 1.200;
+ int22_ar[U][A][A][U][G][G][U][G] = 2.000;
+ int22_ar[U][A][A][U][G][U][U][G] = 2.000;
+ int22_ar[U][A][A][U][U][A][U][G] = 2.900;
+ int22_ar[U][A][A][U][U][C][U][G] = 1.900;
+ int22_ar[U][A][A][U][U][G][U][G] = 2.700;
+ int22_ar[U][A][A][U][U][U][U][G] = 2.000;
+ int22_ar[U][A][C][A][A][A][U][G] = 2.300;
+ int22_ar[U][A][C][A][A][C][U][G] = 3.400;
+ int22_ar[U][A][C][A][A][G][U][G] = 2.000;
+ int22_ar[U][A][C][A][A][U][U][G] = 3.100;
+ int22_ar[U][A][C][A][C][A][U][G] = 1.900;
+ int22_ar[U][A][C][A][C][C][U][G] = 2.300;
+ int22_ar[U][A][C][A][C][G][U][G] = 2.000;
+ int22_ar[U][A][C][A][C][U][U][G] = 2.000;
+ int22_ar[U][A][C][A][G][A][U][G] = 1.300;
+ int22_ar[U][A][C][A][G][C][U][G] = 2.700;
+ int22_ar[U][A][C][A][G][G][U][G] = 2.000;
+ int22_ar[U][A][C][A][G][U][U][G] = 2.400;
+ int22_ar[U][A][C][A][U][A][U][G] = 2.000;
+ int22_ar[U][A][C][A][U][C][U][G] = 2.000;
+ int22_ar[U][A][C][A][U][G][U][G] = 2.000;
+ int22_ar[U][A][C][A][U][U][U][G] = 2.000;
+ int22_ar[U][A][C][C][A][A][U][G] = 2.300;
+ int22_ar[U][A][C][C][A][C][U][G] = 2.800;
+ int22_ar[U][A][C][C][A][G][U][G] = 2.000;
+ int22_ar[U][A][C][C][A][U][U][G] = 2.500;
+ int22_ar[U][A][C][C][C][A][U][G] = 2.300;
+ int22_ar[U][A][C][C][C][C][U][G] = 2.800;
+ int22_ar[U][A][C][C][C][G][U][G] = 2.000;
+ int22_ar[U][A][C][C][C][U][U][G] = 2.500;
+ int22_ar[U][A][C][C][G][A][U][G] = 2.000;
+ int22_ar[U][A][C][C][G][C][U][G] = 2.000;
+ int22_ar[U][A][C][C][G][G][U][G] = 2.000;
+ int22_ar[U][A][C][C][G][U][U][G] = 2.000;
+ int22_ar[U][A][C][C][U][A][U][G] = 2.300;
+ int22_ar[U][A][C][C][U][C][U][G] = 2.800;
+ int22_ar[U][A][C][C][U][G][U][G] = 2.000;
+ int22_ar[U][A][C][C][U][U][U][G] = 2.500;
+ int22_ar[U][A][C][G][A][A][U][G] = 1.300;
+ int22_ar[U][A][C][G][A][C][U][G] = 2.700;
+ int22_ar[U][A][C][G][A][G][U][G] = 2.000;
+ int22_ar[U][A][C][G][A][U][U][G] = 2.400;
+ int22_ar[U][A][C][G][C][A][U][G] = 2.000;
+ int22_ar[U][A][C][G][C][C][U][G] = 2.000;
+ int22_ar[U][A][C][G][C][G][U][G] = 2.000;
+ int22_ar[U][A][C][G][C][U][U][G] = 2.000;
+ int22_ar[U][A][C][G][G][A][U][G] = 1.700;
+ int22_ar[U][A][C][G][G][C][U][G] = 2.700;
+ int22_ar[U][A][C][G][G][G][U][G] = 2.000;
+ int22_ar[U][A][C][G][G][U][U][G] = 2.400;
+ int22_ar[U][A][C][G][U][A][U][G] = -0.500;
+ int22_ar[U][A][C][G][U][C][U][G] = 1.000;
+ int22_ar[U][A][C][G][U][G][U][G] = 2.000;
+ int22_ar[U][A][C][G][U][U][U][G] = 0.700;
+ int22_ar[U][A][C][U][A][A][U][G] = 2.000;
+ int22_ar[U][A][C][U][A][C][U][G] = 2.000;
+ int22_ar[U][A][C][U][A][G][U][G] = 2.000;
+ int22_ar[U][A][C][U][A][U][U][G] = 2.000;
+ int22_ar[U][A][C][U][C][A][U][G] = 2.000;
+ int22_ar[U][A][C][U][C][C][U][G] = 2.500;
+ int22_ar[U][A][C][U][C][G][U][G] = 2.000;
+ int22_ar[U][A][C][U][C][U][U][G] = 2.200;
+ int22_ar[U][A][C][U][G][A][U][G] = 0.800;
+ int22_ar[U][A][C][U][G][C][U][G] = 2.200;
+ int22_ar[U][A][C][U][G][G][U][G] = 2.000;
+ int22_ar[U][A][C][U][G][U][U][G] = 1.900;
+ int22_ar[U][A][C][U][U][A][U][G] = 1.500;
+ int22_ar[U][A][C][U][U][C][U][G] = 1.900;
+ int22_ar[U][A][C][U][U][G][U][G] = 2.000;
+ int22_ar[U][A][C][U][U][U][U][G] = 1.600;
+ int22_ar[U][A][G][A][A][A][U][G] = 1.700;
+ int22_ar[U][A][G][A][A][C][U][G] = 2.000;
+ int22_ar[U][A][G][A][A][G][U][G] = 2.100;
+ int22_ar[U][A][G][A][A][U][U][G] = 2.200;
+ int22_ar[U][A][G][A][C][A][U][G] = 1.300;
+ int22_ar[U][A][G][A][C][C][U][G] = 2.000;
+ int22_ar[U][A][G][A][C][G][U][G] = 1.700;
+ int22_ar[U][A][G][A][C][U][U][G] = 0.800;
+ int22_ar[U][A][G][A][G][A][U][G] = 0.700;
+ int22_ar[U][A][G][A][G][C][U][G] = 2.000;
+ int22_ar[U][A][G][A][G][G][U][G] = 1.100;
+ int22_ar[U][A][G][A][G][U][U][G] = 2.000;
+ int22_ar[U][A][G][A][U][A][U][G] = 2.000;
+ int22_ar[U][A][G][A][U][C][U][G] = 2.000;
+ int22_ar[U][A][G][A][U][G][U][G] = 2.000;
+ int22_ar[U][A][G][A][U][U][U][G] = 2.000;
+ int22_ar[U][A][G][C][A][A][U][G] = 1.700;
+ int22_ar[U][A][G][C][A][C][U][G] = 2.000;
+ int22_ar[U][A][G][C][A][G][U][G] = 2.100;
+ int22_ar[U][A][G][C][A][U][U][G] = 1.200;
+ int22_ar[U][A][G][C][C][A][U][G] = 2.700;
+ int22_ar[U][A][G][C][C][C][U][G] = 2.000;
+ int22_ar[U][A][G][C][C][G][U][G] = 2.700;
+ int22_ar[U][A][G][C][C][U][U][G] = 2.200;
+ int22_ar[U][A][G][C][G][A][U][G] = 2.000;
+ int22_ar[U][A][G][C][G][C][U][G] = 2.000;
+ int22_ar[U][A][G][C][G][G][U][G] = 2.000;
+ int22_ar[U][A][G][C][G][U][U][G] = 2.000;
+ int22_ar[U][A][G][C][U][A][U][G] = 2.700;
+ int22_ar[U][A][G][C][U][C][U][G] = 2.000;
+ int22_ar[U][A][G][C][U][G][U][G] = 2.700;
+ int22_ar[U][A][G][C][U][U][U][G] = 2.200;
+ int22_ar[U][A][G][G][A][A][U][G] = 0.700;
+ int22_ar[U][A][G][G][A][C][U][G] = 2.000;
+ int22_ar[U][A][G][G][A][G][U][G] = 1.100;
+ int22_ar[U][A][G][G][A][U][U][G] = 2.000;
+ int22_ar[U][A][G][G][C][A][U][G] = 2.000;
+ int22_ar[U][A][G][G][C][C][U][G] = 2.000;
+ int22_ar[U][A][G][G][C][G][U][G] = 2.000;
+ int22_ar[U][A][G][G][C][U][U][G] = 2.000;
+ int22_ar[U][A][G][G][G][A][U][G] = 1.100;
+ int22_ar[U][A][G][G][G][C][U][G] = 2.000;
+ int22_ar[U][A][G][G][G][G][U][G] = 1.500;
+ int22_ar[U][A][G][G][G][U][U][G] = 1.600;
+ int22_ar[U][A][G][G][U][A][U][G] = 0.700;
+ int22_ar[U][A][G][G][U][C][U][G] = 2.000;
+ int22_ar[U][A][G][G][U][G][U][G] = 0.300;
+ int22_ar[U][A][G][G][U][U][U][G] = -1.600;
+ int22_ar[U][A][G][U][A][A][U][G] = 2.000;
+ int22_ar[U][A][G][U][A][C][U][G] = 2.000;
+ int22_ar[U][A][G][U][A][G][U][G] = 2.000;
+ int22_ar[U][A][G][U][A][U][U][G] = 2.000;
+ int22_ar[U][A][G][U][C][A][U][G] = 2.400;
+ int22_ar[U][A][G][U][C][C][U][G] = 2.000;
+ int22_ar[U][A][G][U][C][G][U][G] = 2.400;
+ int22_ar[U][A][G][U][C][U][U][G] = 1.900;
+ int22_ar[U][A][G][U][G][A][U][G] = 2.000;
+ int22_ar[U][A][G][U][G][C][U][G] = 2.000;
+ int22_ar[U][A][G][U][G][G][U][G] = 1.600;
+ int22_ar[U][A][G][U][G][U][U][G] = -0.300;
+ int22_ar[U][A][G][U][U][A][U][G] = 2.700;
+ int22_ar[U][A][G][U][U][C][U][G] = 2.000;
+ int22_ar[U][A][G][U][U][G][U][G] = 2.300;
+ int22_ar[U][A][G][U][U][U][U][G] = 2.200;
+ int22_ar[U][A][U][A][A][A][U][G] = 2.000;
+ int22_ar[U][A][U][A][A][C][U][G] = 3.400;
+ int22_ar[U][A][U][A][A][G][U][G] = 1.000;
+ int22_ar[U][A][U][A][A][U][U][G] = 2.900;
+ int22_ar[U][A][U][A][C][A][U][G] = 2.000;
+ int22_ar[U][A][U][A][C][C][U][G] = 2.300;
+ int22_ar[U][A][U][A][C][G][U][G] = -0.500;
+ int22_ar[U][A][U][A][C][U][U][G] = 1.500;
+ int22_ar[U][A][U][A][G][A][U][G] = 2.000;
+ int22_ar[U][A][U][A][G][C][U][G] = 2.700;
+ int22_ar[U][A][U][A][G][G][U][G] = 0.700;
+ int22_ar[U][A][U][A][G][U][U][G] = 2.700;
+ int22_ar[U][A][U][A][U][A][U][G] = 2.000;
+ int22_ar[U][A][U][A][U][C][U][G] = 2.000;
+ int22_ar[U][A][U][A][U][G][U][G] = 2.000;
+ int22_ar[U][A][U][A][U][U][U][G] = 2.000;
+ int22_ar[U][A][U][C][A][A][U][G] = 2.000;
+ int22_ar[U][A][U][C][A][C][U][G] = 2.800;
+ int22_ar[U][A][U][C][A][G][U][G] = 0.000;
+ int22_ar[U][A][U][C][A][U][U][G] = 1.900;
+ int22_ar[U][A][U][C][C][A][U][G] = 2.000;
+ int22_ar[U][A][U][C][C][C][U][G] = 2.800;
+ int22_ar[U][A][U][C][C][G][U][G] = 1.000;
+ int22_ar[U][A][U][C][C][U][U][G] = 1.900;
+ int22_ar[U][A][U][C][G][A][U][G] = 2.000;
+ int22_ar[U][A][U][C][G][C][U][G] = 2.000;
+ int22_ar[U][A][U][C][G][G][U][G] = 2.000;
+ int22_ar[U][A][U][C][G][U][U][G] = 2.000;
+ int22_ar[U][A][U][C][U][A][U][G] = 2.000;
+ int22_ar[U][A][U][C][U][C][U][G] = 2.800;
+ int22_ar[U][A][U][C][U][G][U][G] = 1.000;
+ int22_ar[U][A][U][C][U][U][U][G] = 1.900;
+ int22_ar[U][A][U][G][A][A][U][G] = 2.000;
+ int22_ar[U][A][U][G][A][C][U][G] = 2.700;
+ int22_ar[U][A][U][G][A][G][U][G] = 0.700;
+ int22_ar[U][A][U][G][A][U][U][G] = 2.700;
+ int22_ar[U][A][U][G][C][A][U][G] = 2.000;
+ int22_ar[U][A][U][G][C][C][U][G] = 2.000;
+ int22_ar[U][A][U][G][C][G][U][G] = 2.000;
+ int22_ar[U][A][U][G][C][U][U][G] = 2.000;
+ int22_ar[U][A][U][G][G][A][U][G] = 2.000;
+ int22_ar[U][A][U][G][G][C][U][G] = 2.700;
+ int22_ar[U][A][U][G][G][G][U][G] = 0.300;
+ int22_ar[U][A][U][G][G][U][U][G] = 2.300;
+ int22_ar[U][A][U][G][U][A][U][G] = 2.000;
+ int22_ar[U][A][U][G][U][C][U][G] = 1.000;
+ int22_ar[U][A][U][G][U][G][U][G] = -2.900;
+ int22_ar[U][A][U][G][U][U][U][G] = 0.900;
+ int22_ar[U][A][U][U][A][A][U][G] = 2.000;
+ int22_ar[U][A][U][U][A][C][U][G] = 2.000;
+ int22_ar[U][A][U][U][A][G][U][G] = 2.000;
+ int22_ar[U][A][U][U][A][U][U][G] = 2.000;
+ int22_ar[U][A][U][U][C][A][U][G] = 2.000;
+ int22_ar[U][A][U][U][C][C][U][G] = 2.500;
+ int22_ar[U][A][U][U][C][G][U][G] = 0.700;
+ int22_ar[U][A][U][U][C][U][U][G] = 1.600;
+ int22_ar[U][A][U][U][G][A][U][G] = 2.000;
+ int22_ar[U][A][U][U][G][C][U][G] = 2.200;
+ int22_ar[U][A][U][U][G][G][U][G] = -1.600;
+ int22_ar[U][A][U][U][G][U][U][G] = 2.200;
+ int22_ar[U][A][U][U][U][A][U][G] = 2.000;
+ int22_ar[U][A][U][U][U][C][U][G] = 1.900;
+ int22_ar[U][A][U][U][U][G][U][G] = 0.900;
+ int22_ar[U][A][U][U][U][U][U][G] = 1.100;
+ int22_ar[U][G][A][A][A][A][A][U] = 2.800;
+ int22_ar[U][G][A][A][A][C][A][U] = 2.800;
+ int22_ar[U][G][A][A][A][G][A][U] = 1.700;
+ int22_ar[U][G][A][A][A][U][A][U] = 2.000;
+ int22_ar[U][G][A][A][C][A][A][U] = 2.500;
+ int22_ar[U][G][A][A][C][C][A][U] = 2.500;
+ int22_ar[U][G][A][A][C][G][A][U] = 1.500;
+ int22_ar[U][G][A][A][C][U][A][U] = 2.000;
+ int22_ar[U][G][A][A][G][A][A][U] = 1.500;
+ int22_ar[U][G][A][A][G][C][A][U] = 1.500;
+ int22_ar[U][G][A][A][G][G][A][U] = 0.500;
+ int22_ar[U][G][A][A][G][U][A][U] = 2.000;
+ int22_ar[U][G][A][A][U][A][A][U] = 2.000;
+ int22_ar[U][G][A][A][U][C][A][U] = 2.000;
+ int22_ar[U][G][A][A][U][G][A][U] = 2.000;
+ int22_ar[U][G][A][A][U][U][A][U] = 2.000;
+ int22_ar[U][G][A][C][A][A][A][U] = 2.600;
+ int22_ar[U][G][A][C][A][C][A][U] = 2.600;
+ int22_ar[U][G][A][C][A][G][A][U] = 1.600;
+ int22_ar[U][G][A][C][A][U][A][U] = 2.000;
+ int22_ar[U][G][A][C][C][A][A][U] = 3.100;
+ int22_ar[U][G][A][C][C][C][A][U] = 2.500;
+ int22_ar[U][G][A][C][C][G][A][U] = 2.400;
+ int22_ar[U][G][A][C][C][U][A][U] = 2.000;
+ int22_ar[U][G][A][C][G][A][A][U] = 2.000;
+ int22_ar[U][G][A][C][G][C][A][U] = 2.000;
+ int22_ar[U][G][A][C][G][G][A][U] = 2.000;
+ int22_ar[U][G][A][C][G][U][A][U] = 2.000;
+ int22_ar[U][G][A][C][U][A][A][U] = 3.100;
+ int22_ar[U][G][A][C][U][C][A][U] = 2.500;
+ int22_ar[U][G][A][C][U][G][A][U] = 2.400;
+ int22_ar[U][G][A][C][U][U][A][U] = 2.000;
+ int22_ar[U][G][A][G][A][A][A][U] = 1.500;
+ int22_ar[U][G][A][G][A][C][A][U] = 1.500;
+ int22_ar[U][G][A][G][A][G][A][U] = 0.500;
+ int22_ar[U][G][A][G][A][U][A][U] = 2.000;
+ int22_ar[U][G][A][G][C][A][A][U] = 2.000;
+ int22_ar[U][G][A][G][C][C][A][U] = 2.000;
+ int22_ar[U][G][A][G][C][G][A][U] = 2.000;
+ int22_ar[U][G][A][G][C][U][A][U] = 2.000;
+ int22_ar[U][G][A][G][G][A][A][U] = 2.100;
+ int22_ar[U][G][A][G][G][C][A][U] = 2.100;
+ int22_ar[U][G][A][G][G][G][A][U] = 1.000;
+ int22_ar[U][G][A][G][G][U][A][U] = 2.000;
+ int22_ar[U][G][A][G][U][A][A][U] = 1.300;
+ int22_ar[U][G][A][G][U][C][A][U] = 0.300;
+ int22_ar[U][G][A][G][U][G][A][U] = 1.100;
+ int22_ar[U][G][A][G][U][U][A][U] = 2.000;
+ int22_ar[U][G][A][U][A][A][A][U] = 2.000;
+ int22_ar[U][G][A][U][A][C][A][U] = 2.000;
+ int22_ar[U][G][A][U][A][G][A][U] = 2.000;
+ int22_ar[U][G][A][U][A][U][A][U] = 2.000;
+ int22_ar[U][G][A][U][C][A][A][U] = 3.100;
+ int22_ar[U][G][A][U][C][C][A][U] = 2.500;
+ int22_ar[U][G][A][U][C][G][A][U] = 2.400;
+ int22_ar[U][G][A][U][C][U][A][U] = 2.000;
+ int22_ar[U][G][A][U][G][A][A][U] = 2.300;
+ int22_ar[U][G][A][U][G][C][A][U] = 1.300;
+ int22_ar[U][G][A][U][G][G][A][U] = 2.100;
+ int22_ar[U][G][A][U][G][U][A][U] = 2.000;
+ int22_ar[U][G][A][U][U][A][A][U] = 2.700;
+ int22_ar[U][G][A][U][U][C][A][U] = 1.700;
+ int22_ar[U][G][A][U][U][G][A][U] = 2.400;
+ int22_ar[U][G][A][U][U][U][A][U] = 2.000;
+ int22_ar[U][G][C][A][A][A][A][U] = 2.300;
+ int22_ar[U][G][C][A][A][C][A][U] = 3.400;
+ int22_ar[U][G][C][A][A][G][A][U] = 2.000;
+ int22_ar[U][G][C][A][A][U][A][U] = 3.100;
+ int22_ar[U][G][C][A][C][A][A][U] = 2.100;
+ int22_ar[U][G][C][A][C][C][A][U] = 2.500;
+ int22_ar[U][G][C][A][C][G][A][U] = 2.000;
+ int22_ar[U][G][C][A][C][U][A][U] = 2.200;
+ int22_ar[U][G][C][A][G][A][A][U] = 1.100;
+ int22_ar[U][G][C][A][G][C][A][U] = 2.500;
+ int22_ar[U][G][C][A][G][G][A][U] = 2.000;
+ int22_ar[U][G][C][A][G][U][A][U] = 2.200;
+ int22_ar[U][G][C][A][U][A][A][U] = 2.000;
+ int22_ar[U][G][C][A][U][C][A][U] = 2.000;
+ int22_ar[U][G][C][A][U][G][A][U] = 2.000;
+ int22_ar[U][G][C][A][U][U][A][U] = 2.000;
+ int22_ar[U][G][C][C][A][A][A][U] = 2.200;
+ int22_ar[U][G][C][C][A][C][A][U] = 2.600;
+ int22_ar[U][G][C][C][A][G][A][U] = 2.000;
+ int22_ar[U][G][C][C][A][U][A][U] = 2.300;
+ int22_ar[U][G][C][C][C][A][A][U] = 2.000;
+ int22_ar[U][G][C][C][C][C][A][U] = 2.500;
+ int22_ar[U][G][C][C][C][G][A][U] = 2.000;
+ int22_ar[U][G][C][C][C][U][A][U] = 2.200;
+ int22_ar[U][G][C][C][G][A][A][U] = 2.000;
+ int22_ar[U][G][C][C][G][C][A][U] = 2.000;
+ int22_ar[U][G][C][C][G][G][A][U] = 2.000;
+ int22_ar[U][G][C][C][G][U][A][U] = 2.000;
+ int22_ar[U][G][C][C][U][A][A][U] = 2.000;
+ int22_ar[U][G][C][C][U][C][A][U] = 2.500;
+ int22_ar[U][G][C][C][U][G][A][U] = 2.000;
+ int22_ar[U][G][C][C][U][U][A][U] = 2.200;
+ int22_ar[U][G][C][G][A][A][A][U] = 1.100;
+ int22_ar[U][G][C][G][A][C][A][U] = 2.500;
+ int22_ar[U][G][C][G][A][G][A][U] = 2.000;
+ int22_ar[U][G][C][G][A][U][A][U] = 2.200;
+ int22_ar[U][G][C][G][C][A][A][U] = 2.000;
+ int22_ar[U][G][C][G][C][C][A][U] = 2.000;
+ int22_ar[U][G][C][G][C][G][A][U] = 2.000;
+ int22_ar[U][G][C][G][C][U][A][U] = 2.000;
+ int22_ar[U][G][C][G][G][A][A][U] = 1.600;
+ int22_ar[U][G][C][G][G][C][A][U] = 2.700;
+ int22_ar[U][G][C][G][G][G][A][U] = 2.000;
+ int22_ar[U][G][C][G][G][U][A][U] = 2.400;
+ int22_ar[U][G][C][G][U][A][A][U] = -0.100;
+ int22_ar[U][G][C][G][U][C][A][U] = 1.300;
+ int22_ar[U][G][C][G][U][G][A][U] = 2.000;
+ int22_ar[U][G][C][G][U][U][A][U] = 1.000;
+ int22_ar[U][G][C][U][A][A][A][U] = 2.000;
+ int22_ar[U][G][C][U][A][C][A][U] = 2.000;
+ int22_ar[U][G][C][U][A][G][A][U] = 2.000;
+ int22_ar[U][G][C][U][A][U][A][U] = 2.000;
+ int22_ar[U][G][C][U][C][A][A][U] = 2.000;
+ int22_ar[U][G][C][U][C][C][A][U] = 2.500;
+ int22_ar[U][G][C][U][C][G][A][U] = 2.000;
+ int22_ar[U][G][C][U][C][U][A][U] = 2.200;
+ int22_ar[U][G][C][U][G][A][A][U] = 0.900;
+ int22_ar[U][G][C][U][G][C][A][U] = 2.300;
+ int22_ar[U][G][C][U][G][G][A][U] = 2.000;
+ int22_ar[U][G][C][U][G][U][A][U] = 2.000;
+ int22_ar[U][G][C][U][U][A][A][U] = 1.200;
+ int22_ar[U][G][C][U][U][C][A][U] = 1.700;
+ int22_ar[U][G][C][U][U][G][A][U] = 2.000;
+ int22_ar[U][G][C][U][U][U][A][U] = 1.400;
+ int22_ar[U][G][G][A][A][A][A][U] = 1.700;
+ int22_ar[U][G][G][A][A][C][A][U] = 2.000;
+ int22_ar[U][G][G][A][A][G][A][U] = 2.100;
+ int22_ar[U][G][G][A][A][U][A][U] = 2.200;
+ int22_ar[U][G][G][A][C][A][A][U] = 1.500;
+ int22_ar[U][G][G][A][C][C][A][U] = 2.000;
+ int22_ar[U][G][G][A][C][G][A][U] = 1.900;
+ int22_ar[U][G][G][A][C][U][A][U] = 1.000;
+ int22_ar[U][G][G][A][G][A][A][U] = 0.500;
+ int22_ar[U][G][G][A][G][C][A][U] = 2.000;
+ int22_ar[U][G][G][A][G][G][A][U] = 0.900;
+ int22_ar[U][G][G][A][G][U][A][U] = 1.800;
+ int22_ar[U][G][G][A][U][A][A][U] = 2.000;
+ int22_ar[U][G][G][A][U][C][A][U] = 2.000;
+ int22_ar[U][G][G][A][U][G][A][U] = 2.000;
+ int22_ar[U][G][G][A][U][U][A][U] = 2.000;
+ int22_ar[U][G][G][C][A][A][A][U] = 1.600;
+ int22_ar[U][G][G][C][A][C][A][U] = 2.000;
+ int22_ar[U][G][G][C][A][G][A][U] = 2.000;
+ int22_ar[U][G][G][C][A][U][A][U] = 1.100;
+ int22_ar[U][G][G][C][C][A][A][U] = 2.400;
+ int22_ar[U][G][G][C][C][C][A][U] = 2.000;
+ int22_ar[U][G][G][C][C][G][A][U] = 2.400;
+ int22_ar[U][G][G][C][C][U][A][U] = 1.900;
+ int22_ar[U][G][G][C][G][A][A][U] = 2.000;
+ int22_ar[U][G][G][C][G][C][A][U] = 2.000;
+ int22_ar[U][G][G][C][G][G][A][U] = 2.000;
+ int22_ar[U][G][G][C][G][U][A][U] = 2.000;
+ int22_ar[U][G][G][C][U][A][A][U] = 2.400;
+ int22_ar[U][G][G][C][U][C][A][U] = 2.000;
+ int22_ar[U][G][G][C][U][G][A][U] = 2.400;
+ int22_ar[U][G][G][C][U][U][A][U] = 1.900;
+ int22_ar[U][G][G][G][A][A][A][U] = 0.500;
+ int22_ar[U][G][G][G][A][C][A][U] = 2.000;
+ int22_ar[U][G][G][G][A][G][A][U] = 0.900;
+ int22_ar[U][G][G][G][A][U][A][U] = 1.800;
+ int22_ar[U][G][G][G][C][A][A][U] = 2.000;
+ int22_ar[U][G][G][G][C][C][A][U] = 2.000;
+ int22_ar[U][G][G][G][C][G][A][U] = 2.000;
+ int22_ar[U][G][G][G][C][U][A][U] = 2.000;
+ int22_ar[U][G][G][G][G][A][A][U] = 1.000;
+ int22_ar[U][G][G][G][G][C][A][U] = 2.000;
+ int22_ar[U][G][G][G][G][G][A][U] = 1.400;
+ int22_ar[U][G][G][G][G][U][A][U] = 1.500;
+ int22_ar[U][G][G][G][U][A][A][U] = 1.100;
+ int22_ar[U][G][G][G][U][C][A][U] = 2.000;
+ int22_ar[U][G][G][G][U][G][A][U] = 0.700;
+ int22_ar[U][G][G][G][U][U][A][U] = -1.200;
+ int22_ar[U][G][G][U][A][A][A][U] = 2.000;
+ int22_ar[U][G][G][U][A][C][A][U] = 2.000;
+ int22_ar[U][G][G][U][A][G][A][U] = 2.000;
+ int22_ar[U][G][G][U][A][U][A][U] = 2.000;
+ int22_ar[U][G][G][U][C][A][A][U] = 2.400;
+ int22_ar[U][G][G][U][C][C][A][U] = 2.000;
+ int22_ar[U][G][G][U][C][G][A][U] = 2.400;
+ int22_ar[U][G][G][U][C][U][A][U] = 1.900;
+ int22_ar[U][G][G][U][G][A][A][U] = 2.100;
+ int22_ar[U][G][G][U][G][C][A][U] = 2.000;
+ int22_ar[U][G][G][U][G][G][A][U] = 1.700;
+ int22_ar[U][G][G][U][G][U][A][U] = -0.200;
+ int22_ar[U][G][G][U][U][A][A][U] = 2.400;
+ int22_ar[U][G][G][U][U][C][A][U] = 2.000;
+ int22_ar[U][G][G][U][U][G][A][U] = 2.000;
+ int22_ar[U][G][G][U][U][U][A][U] = 1.900;
+ int22_ar[U][G][U][A][A][A][A][U] = 2.000;
+ int22_ar[U][G][U][A][A][C][A][U] = 3.400;
+ int22_ar[U][G][U][A][A][G][A][U] = 1.000;
+ int22_ar[U][G][U][A][A][U][A][U] = 2.900;
+ int22_ar[U][G][U][A][C][A][A][U] = 2.000;
+ int22_ar[U][G][U][A][C][C][A][U] = 2.500;
+ int22_ar[U][G][U][A][C][G][A][U] = -0.300;
+ int22_ar[U][G][U][A][C][U][A][U] = 1.700;
+ int22_ar[U][G][U][A][G][A][A][U] = 2.000;
+ int22_ar[U][G][U][A][G][C][A][U] = 2.500;
+ int22_ar[U][G][U][A][G][G][A][U] = 0.500;
+ int22_ar[U][G][U][A][G][U][A][U] = 2.500;
+ int22_ar[U][G][U][A][U][A][A][U] = 2.000;
+ int22_ar[U][G][U][A][U][C][A][U] = 2.000;
+ int22_ar[U][G][U][A][U][G][A][U] = 2.000;
+ int22_ar[U][G][U][A][U][U][A][U] = 2.000;
+ int22_ar[U][G][U][C][A][A][A][U] = 2.000;
+ int22_ar[U][G][U][C][A][C][A][U] = 2.600;
+ int22_ar[U][G][U][C][A][G][A][U] = -0.200;
+ int22_ar[U][G][U][C][A][U][A][U] = 1.800;
+ int22_ar[U][G][U][C][C][A][A][U] = 2.000;
+ int22_ar[U][G][U][C][C][C][A][U] = 2.500;
+ int22_ar[U][G][U][C][C][G][A][U] = 0.700;
+ int22_ar[U][G][U][C][C][U][A][U] = 1.600;
+ int22_ar[U][G][U][C][G][A][A][U] = 2.000;
+ int22_ar[U][G][U][C][G][C][A][U] = 2.000;
+ int22_ar[U][G][U][C][G][G][A][U] = 2.000;
+ int22_ar[U][G][U][C][G][U][A][U] = 2.000;
+ int22_ar[U][G][U][C][U][A][A][U] = 2.000;
+ int22_ar[U][G][U][C][U][C][A][U] = 2.500;
+ int22_ar[U][G][U][C][U][G][A][U] = 0.700;
+ int22_ar[U][G][U][C][U][U][A][U] = 1.600;
+ int22_ar[U][G][U][G][A][A][A][U] = 2.000;
+ int22_ar[U][G][U][G][A][C][A][U] = 2.500;
+ int22_ar[U][G][U][G][A][G][A][U] = 0.500;
+ int22_ar[U][G][U][G][A][U][A][U] = 2.500;
+ int22_ar[U][G][U][G][C][A][A][U] = 2.000;
+ int22_ar[U][G][U][G][C][C][A][U] = 2.000;
+ int22_ar[U][G][U][G][C][G][A][U] = 2.000;
+ int22_ar[U][G][U][G][C][U][A][U] = 2.000;
+ int22_ar[U][G][U][G][G][A][A][U] = 2.000;
+ int22_ar[U][G][U][G][G][C][A][U] = 2.700;
+ int22_ar[U][G][U][G][G][G][A][U] = 0.300;
+ int22_ar[U][G][U][G][G][U][A][U] = 2.200;
+ int22_ar[U][G][U][G][U][A][A][U] = 2.000;
+ int22_ar[U][G][U][G][U][C][A][U] = 1.300;
+ int22_ar[U][G][U][G][U][G][A][U] = -2.500;
+ int22_ar[U][G][U][G][U][U][A][U] = 1.300;
+ int22_ar[U][G][U][U][A][A][A][U] = 2.000;
+ int22_ar[U][G][U][U][A][C][A][U] = 2.000;
+ int22_ar[U][G][U][U][A][G][A][U] = 2.000;
+ int22_ar[U][G][U][U][A][U][A][U] = 2.000;
+ int22_ar[U][G][U][U][C][A][A][U] = 2.000;
+ int22_ar[U][G][U][U][C][C][A][U] = 2.500;
+ int22_ar[U][G][U][U][C][G][A][U] = 0.700;
+ int22_ar[U][G][U][U][C][U][A][U] = 1.600;
+ int22_ar[U][G][U][U][G][A][A][U] = 2.000;
+ int22_ar[U][G][U][U][G][C][A][U] = 2.300;
+ int22_ar[U][G][U][U][G][G][A][U] = -1.500;
+ int22_ar[U][G][U][U][G][U][A][U] = 2.300;
+ int22_ar[U][G][U][U][U][A][A][U] = 2.000;
+ int22_ar[U][G][U][U][U][C][A][U] = 1.700;
+ int22_ar[U][G][U][U][U][G][A][U] = 0.700;
+ int22_ar[U][G][U][U][U][U][A][U] = 0.800;
+ int22_ar[U][G][A][A][A][A][C][G] = 2.000;
+ int22_ar[U][G][A][A][A][C][C][G] = 2.000;
+ int22_ar[U][G][A][A][A][G][C][G] = 1.000;
+ int22_ar[U][G][A][A][A][U][C][G] = 2.000;
+ int22_ar[U][G][A][A][C][A][C][G] = 1.900;
+ int22_ar[U][G][A][A][C][C][C][G] = 1.900;
+ int22_ar[U][G][A][A][C][G][C][G] = 0.900;
+ int22_ar[U][G][A][A][C][U][C][G] = 2.000;
+ int22_ar[U][G][A][A][G][A][C][G] = 1.000;
+ int22_ar[U][G][A][A][G][C][C][G] = 1.000;
+ int22_ar[U][G][A][A][G][G][C][G] = 0.000;
+ int22_ar[U][G][A][A][G][U][C][G] = 2.000;
+ int22_ar[U][G][A][A][U][A][C][G] = 2.000;
+ int22_ar[U][G][A][A][U][C][C][G] = 2.000;
+ int22_ar[U][G][A][A][U][G][C][G] = 2.000;
+ int22_ar[U][G][A][A][U][U][C][G] = 2.000;
+ int22_ar[U][G][A][C][A][A][C][G] = 2.400;
+ int22_ar[U][G][A][C][A][C][C][G] = 2.400;
+ int22_ar[U][G][A][C][A][G][C][G] = 1.300;
+ int22_ar[U][G][A][C][A][U][C][G] = 2.000;
+ int22_ar[U][G][A][C][C][A][C][G] = 2.800;
+ int22_ar[U][G][A][C][C][C][C][G] = 2.200;
+ int22_ar[U][G][A][C][C][G][C][G] = 2.200;
+ int22_ar[U][G][A][C][C][U][C][G] = 2.000;
+ int22_ar[U][G][A][C][G][A][C][G] = 2.000;
+ int22_ar[U][G][A][C][G][C][C][G] = 2.000;
+ int22_ar[U][G][A][C][G][G][C][G] = 2.000;
+ int22_ar[U][G][A][C][G][U][C][G] = 2.000;
+ int22_ar[U][G][A][C][U][A][C][G] = 2.700;
+ int22_ar[U][G][A][C][U][C][C][G] = 2.100;
+ int22_ar[U][G][A][C][U][G][C][G] = 2.000;
+ int22_ar[U][G][A][C][U][U][C][G] = 2.000;
+ int22_ar[U][G][A][G][A][A][C][G] = 1.000;
+ int22_ar[U][G][A][G][A][C][C][G] = 1.000;
+ int22_ar[U][G][A][G][A][G][C][G] = 0.000;
+ int22_ar[U][G][A][G][A][U][C][G] = 2.000;
+ int22_ar[U][G][A][G][C][A][C][G] = 2.000;
+ int22_ar[U][G][A][G][C][C][C][G] = 2.000;
+ int22_ar[U][G][A][G][C][G][C][G] = 2.000;
+ int22_ar[U][G][A][G][C][U][C][G] = 2.000;
+ int22_ar[U][G][A][G][G][A][C][G] = 1.800;
+ int22_ar[U][G][A][G][G][C][C][G] = 1.800;
+ int22_ar[U][G][A][G][G][G][C][G] = 0.700;
+ int22_ar[U][G][A][G][G][U][C][G] = 2.000;
+ int22_ar[U][G][A][G][U][A][C][G] = 0.300;
+ int22_ar[U][G][A][G][U][C][C][G] = -0.700;
+ int22_ar[U][G][A][G][U][G][C][G] = 0.100;
+ int22_ar[U][G][A][G][U][U][C][G] = 2.000;
+ int22_ar[U][G][A][U][A][A][C][G] = 2.000;
+ int22_ar[U][G][A][U][A][C][C][G] = 2.000;
+ int22_ar[U][G][A][U][A][G][C][G] = 2.000;
+ int22_ar[U][G][A][U][A][U][C][G] = 2.000;
+ int22_ar[U][G][A][U][C][A][C][G] = 2.700;
+ int22_ar[U][G][A][U][C][C][C][G] = 2.100;
+ int22_ar[U][G][A][U][C][G][C][G] = 2.000;
+ int22_ar[U][G][A][U][C][U][C][G] = 2.000;
+ int22_ar[U][G][A][U][G][A][C][G] = 1.800;
+ int22_ar[U][G][A][U][G][C][C][G] = 0.800;
+ int22_ar[U][G][A][U][G][G][C][G] = 1.600;
+ int22_ar[U][G][A][U][G][U][C][G] = 2.000;
+ int22_ar[U][G][A][U][U][A][C][G] = 2.200;
+ int22_ar[U][G][A][U][U][C][C][G] = 1.200;
+ int22_ar[U][G][A][U][U][G][C][G] = 1.900;
+ int22_ar[U][G][A][U][U][U][C][G] = 2.000;
+ int22_ar[U][G][C][A][A][A][C][G] = 1.600;
+ int22_ar[U][G][C][A][A][C][C][G] = 2.600;
+ int22_ar[U][G][C][A][A][G][C][G] = 2.000;
+ int22_ar[U][G][C][A][A][U][C][G] = 2.300;
+ int22_ar[U][G][C][A][C][A][C][G] = 1.500;
+ int22_ar[U][G][C][A][C][C][C][G] = 1.900;
+ int22_ar[U][G][C][A][C][G][C][G] = 2.000;
+ int22_ar[U][G][C][A][C][U][C][G] = 1.600;
+ int22_ar[U][G][C][A][G][A][C][G] = 0.600;
+ int22_ar[U][G][C][A][G][C][C][G] = 2.000;
+ int22_ar[U][G][C][A][G][G][C][G] = 2.000;
+ int22_ar[U][G][C][A][G][U][C][G] = 1.700;
+ int22_ar[U][G][C][A][U][A][C][G] = 2.000;
+ int22_ar[U][G][C][A][U][C][C][G] = 2.000;
+ int22_ar[U][G][C][A][U][G][C][G] = 2.000;
+ int22_ar[U][G][C][A][U][U][C][G] = 2.000;
+ int22_ar[U][G][C][C][A][A][C][G] = 1.900;
+ int22_ar[U][G][C][C][A][C][C][G] = 2.400;
+ int22_ar[U][G][C][C][A][G][C][G] = 2.000;
+ int22_ar[U][G][C][C][A][U][C][G] = 2.100;
+ int22_ar[U][G][C][C][C][A][C][G] = 1.800;
+ int22_ar[U][G][C][C][C][C][C][G] = 2.200;
+ int22_ar[U][G][C][C][C][G][C][G] = 2.000;
+ int22_ar[U][G][C][C][C][U][C][G] = 1.900;
+ int22_ar[U][G][C][C][G][A][C][G] = 2.000;
+ int22_ar[U][G][C][C][G][C][C][G] = 2.000;
+ int22_ar[U][G][C][C][G][G][C][G] = 2.000;
+ int22_ar[U][G][C][C][G][U][C][G] = 2.000;
+ int22_ar[U][G][C][C][U][A][C][G] = 1.600;
+ int22_ar[U][G][C][C][U][C][C][G] = 2.100;
+ int22_ar[U][G][C][C][U][G][C][G] = 2.000;
+ int22_ar[U][G][C][C][U][U][C][G] = 1.800;
+ int22_ar[U][G][C][G][A][A][C][G] = 0.600;
+ int22_ar[U][G][C][G][A][C][C][G] = 2.000;
+ int22_ar[U][G][C][G][A][G][C][G] = 2.000;
+ int22_ar[U][G][C][G][A][U][C][G] = 1.700;
+ int22_ar[U][G][C][G][C][A][C][G] = 2.000;
+ int22_ar[U][G][C][G][C][C][C][G] = 2.000;
+ int22_ar[U][G][C][G][C][G][C][G] = 2.000;
+ int22_ar[U][G][C][G][C][U][C][G] = 2.000;
+ int22_ar[U][G][C][G][G][A][C][G] = 1.300;
+ int22_ar[U][G][C][G][G][C][C][G] = 2.400;
+ int22_ar[U][G][C][G][G][G][C][G] = 2.000;
+ int22_ar[U][G][C][G][G][U][C][G] = 2.100;
+ int22_ar[U][G][C][G][U][A][C][G] = -1.100;
+ int22_ar[U][G][C][G][U][C][C][G] = 0.300;
+ int22_ar[U][G][C][G][U][G][C][G] = 2.000;
+ int22_ar[U][G][C][G][U][U][C][G] = 0.000;
+ int22_ar[U][G][C][U][A][A][C][G] = 2.000;
+ int22_ar[U][G][C][U][A][C][C][G] = 2.000;
+ int22_ar[U][G][C][U][A][G][C][G] = 2.000;
+ int22_ar[U][G][C][U][A][U][C][G] = 2.000;
+ int22_ar[U][G][C][U][C][A][C][G] = 1.600;
+ int22_ar[U][G][C][U][C][C][C][G] = 2.100;
+ int22_ar[U][G][C][U][C][G][C][G] = 2.000;
+ int22_ar[U][G][C][U][C][U][C][G] = 1.800;
+ int22_ar[U][G][C][U][G][A][C][G] = 0.400;
+ int22_ar[U][G][C][U][G][C][C][G] = 1.800;
+ int22_ar[U][G][C][U][G][G][C][G] = 2.000;
+ int22_ar[U][G][C][U][G][U][C][G] = 1.500;
+ int22_ar[U][G][C][U][U][A][C][G] = 0.700;
+ int22_ar[U][G][C][U][U][C][C][G] = 1.200;
+ int22_ar[U][G][C][U][U][G][C][G] = 2.000;
+ int22_ar[U][G][C][U][U][U][C][G] = 0.900;
+ int22_ar[U][G][G][A][A][A][C][G] = 1.000;
+ int22_ar[U][G][G][A][A][C][C][G] = 2.000;
+ int22_ar[U][G][G][A][A][G][C][G] = 1.400;
+ int22_ar[U][G][G][A][A][U][C][G] = 1.500;
+ int22_ar[U][G][G][A][C][A][C][G] = 0.900;
+ int22_ar[U][G][G][A][C][C][C][G] = 2.000;
+ int22_ar[U][G][G][A][C][G][C][G] = 1.300;
+ int22_ar[U][G][G][A][C][U][C][G] = 0.400;
+ int22_ar[U][G][G][A][G][A][C][G] = 0.000;
+ int22_ar[U][G][G][A][G][C][C][G] = 2.000;
+ int22_ar[U][G][G][A][G][G][C][G] = 0.400;
+ int22_ar[U][G][G][A][G][U][C][G] = 1.300;
+ int22_ar[U][G][G][A][U][A][C][G] = 2.000;
+ int22_ar[U][G][G][A][U][C][C][G] = 2.000;
+ int22_ar[U][G][G][A][U][G][C][G] = 2.000;
+ int22_ar[U][G][G][A][U][U][C][G] = 2.000;
+ int22_ar[U][G][G][C][A][A][C][G] = 1.300;
+ int22_ar[U][G][G][C][A][C][C][G] = 2.000;
+ int22_ar[U][G][G][C][A][G][C][G] = 1.700;
+ int22_ar[U][G][G][C][A][U][C][G] = 0.800;
+ int22_ar[U][G][G][C][C][A][C][G] = 2.200;
+ int22_ar[U][G][G][C][C][C][C][G] = 2.000;
+ int22_ar[U][G][G][C][C][G][C][G] = 2.200;
+ int22_ar[U][G][G][C][C][U][C][G] = 1.700;
+ int22_ar[U][G][G][C][G][A][C][G] = 2.000;
+ int22_ar[U][G][G][C][G][C][C][G] = 2.000;
+ int22_ar[U][G][G][C][G][G][C][G] = 2.000;
+ int22_ar[U][G][G][C][G][U][C][G] = 2.000;
+ int22_ar[U][G][G][C][U][A][C][G] = 2.000;
+ int22_ar[U][G][G][C][U][C][C][G] = 2.000;
+ int22_ar[U][G][G][C][U][G][C][G] = 2.000;
+ int22_ar[U][G][G][C][U][U][C][G] = 1.500;
+ int22_ar[U][G][G][G][A][A][C][G] = 0.000;
+ int22_ar[U][G][G][G][A][C][C][G] = 2.000;
+ int22_ar[U][G][G][G][A][G][C][G] = 0.400;
+ int22_ar[U][G][G][G][A][U][C][G] = 1.300;
+ int22_ar[U][G][G][G][C][A][C][G] = 2.000;
+ int22_ar[U][G][G][G][C][C][C][G] = 2.000;
+ int22_ar[U][G][G][G][C][G][C][G] = 2.000;
+ int22_ar[U][G][G][G][C][U][C][G] = 2.000;
+ int22_ar[U][G][G][G][G][A][C][G] = 0.700;
+ int22_ar[U][G][G][G][G][C][C][G] = 2.000;
+ int22_ar[U][G][G][G][G][G][C][G] = 1.100;
+ int22_ar[U][G][G][G][G][U][C][G] = 1.200;
+ int22_ar[U][G][G][G][U][A][C][G] = 0.100;
+ int22_ar[U][G][G][G][U][C][C][G] = 2.000;
+ int22_ar[U][G][G][G][U][G][C][G] = -0.300;
+ int22_ar[U][G][G][G][U][U][C][G] = -2.200;
+ int22_ar[U][G][G][U][A][A][C][G] = 2.000;
+ int22_ar[U][G][G][U][A][C][C][G] = 2.000;
+ int22_ar[U][G][G][U][A][G][C][G] = 2.000;
+ int22_ar[U][G][G][U][A][U][C][G] = 2.000;
+ int22_ar[U][G][G][U][C][A][C][G] = 2.000;
+ int22_ar[U][G][G][U][C][C][C][G] = 2.000;
+ int22_ar[U][G][G][U][C][G][C][G] = 2.000;
+ int22_ar[U][G][G][U][C][U][C][G] = 1.500;
+ int22_ar[U][G][G][U][G][A][C][G] = 1.600;
+ int22_ar[U][G][G][U][G][C][C][G] = 2.000;
+ int22_ar[U][G][G][U][G][G][C][G] = 1.200;
+ int22_ar[U][G][G][U][G][U][C][G] = -0.700;
+ int22_ar[U][G][G][U][U][A][C][G] = 1.900;
+ int22_ar[U][G][G][U][U][C][C][G] = 2.000;
+ int22_ar[U][G][G][U][U][G][C][G] = 1.500;
+ int22_ar[U][G][G][U][U][U][C][G] = 1.500;
+ int22_ar[U][G][U][A][A][A][C][G] = 2.000;
+ int22_ar[U][G][U][A][A][C][C][G] = 2.600;
+ int22_ar[U][G][U][A][A][G][C][G] = 0.200;
+ int22_ar[U][G][U][A][A][U][C][G] = 2.200;
+ int22_ar[U][G][U][A][C][A][C][G] = 2.000;
+ int22_ar[U][G][U][A][C][C][C][G] = 1.900;
+ int22_ar[U][G][U][A][C][G][C][G] = -0.900;
+ int22_ar[U][G][U][A][C][U][C][G] = 1.100;
+ int22_ar[U][G][U][A][G][A][C][G] = 2.000;
+ int22_ar[U][G][U][A][G][C][C][G] = 2.000;
+ int22_ar[U][G][U][A][G][G][C][G] = 0.000;
+ int22_ar[U][G][U][A][G][U][C][G] = 2.000;
+ int22_ar[U][G][U][A][U][A][C][G] = 2.000;
+ int22_ar[U][G][U][A][U][C][C][G] = 2.000;
+ int22_ar[U][G][U][A][U][G][C][G] = 2.000;
+ int22_ar[U][G][U][A][U][U][C][G] = 2.000;
+ int22_ar[U][G][U][C][A][A][C][G] = 2.000;
+ int22_ar[U][G][U][C][A][C][C][G] = 2.400;
+ int22_ar[U][G][U][C][A][G][C][G] = -0.400;
+ int22_ar[U][G][U][C][A][U][C][G] = 1.500;
+ int22_ar[U][G][U][C][C][A][C][G] = 2.000;
+ int22_ar[U][G][U][C][C][C][C][G] = 2.200;
+ int22_ar[U][G][U][C][C][G][C][G] = 0.400;
+ int22_ar[U][G][U][C][C][U][C][G] = 1.400;
+ int22_ar[U][G][U][C][G][A][C][G] = 2.000;
+ int22_ar[U][G][U][C][G][C][C][G] = 2.000;
+ int22_ar[U][G][U][C][G][G][C][G] = 2.000;
+ int22_ar[U][G][U][C][G][U][C][G] = 2.000;
+ int22_ar[U][G][U][C][U][A][C][G] = 2.000;
+ int22_ar[U][G][U][C][U][C][C][G] = 2.100;
+ int22_ar[U][G][U][C][U][G][C][G] = 0.300;
+ int22_ar[U][G][U][C][U][U][C][G] = 1.200;
+ int22_ar[U][G][U][G][A][A][C][G] = 2.000;
+ int22_ar[U][G][U][G][A][C][C][G] = 2.000;
+ int22_ar[U][G][U][G][A][G][C][G] = 0.000;
+ int22_ar[U][G][U][G][A][U][C][G] = 2.000;
+ int22_ar[U][G][U][G][C][A][C][G] = 2.000;
+ int22_ar[U][G][U][G][C][C][C][G] = 2.000;
+ int22_ar[U][G][U][G][C][G][C][G] = 2.000;
+ int22_ar[U][G][U][G][C][U][C][G] = 2.000;
+ int22_ar[U][G][U][G][G][A][C][G] = 2.000;
+ int22_ar[U][G][U][G][G][C][C][G] = 2.400;
+ int22_ar[U][G][U][G][G][G][C][G] = 0.000;
+ int22_ar[U][G][U][G][G][U][C][G] = 1.900;
+ int22_ar[U][G][U][G][U][A][C][G] = 2.000;
+ int22_ar[U][G][U][G][U][C][C][G] = 0.300;
+ int22_ar[U][G][U][G][U][G][C][G] = -3.500;
+ int22_ar[U][G][U][G][U][U][C][G] = 0.300;
+ int22_ar[U][G][U][U][A][A][C][G] = 2.000;
+ int22_ar[U][G][U][U][A][C][C][G] = 2.000;
+ int22_ar[U][G][U][U][A][G][C][G] = 2.000;
+ int22_ar[U][G][U][U][A][U][C][G] = 2.000;
+ int22_ar[U][G][U][U][C][A][C][G] = 2.000;
+ int22_ar[U][G][U][U][C][C][C][G] = 2.100;
+ int22_ar[U][G][U][U][C][G][C][G] = 0.300;
+ int22_ar[U][G][U][U][C][U][C][G] = 1.200;
+ int22_ar[U][G][U][U][G][A][C][G] = 2.000;
+ int22_ar[U][G][U][U][G][C][C][G] = 1.800;
+ int22_ar[U][G][U][U][G][G][C][G] = -2.000;
+ int22_ar[U][G][U][U][G][U][C][G] = 1.800;
+ int22_ar[U][G][U][U][U][A][C][G] = 2.000;
+ int22_ar[U][G][U][U][U][C][C][G] = 1.200;
+ int22_ar[U][G][U][U][U][G][C][G] = 0.200;
+ int22_ar[U][G][U][U][U][U][C][G] = 0.300;
+ int22_ar[U][G][A][A][A][A][G][C] = 2.100;
+ int22_ar[U][G][A][A][A][C][G][C] = 2.100;
+ int22_ar[U][G][A][A][A][G][G][C] = 1.100;
+ int22_ar[U][G][A][A][A][U][G][C] = 2.000;
+ int22_ar[U][G][A][A][C][A][G][C] = 1.900;
+ int22_ar[U][G][A][A][C][C][G][C] = 1.900;
+ int22_ar[U][G][A][A][C][G][G][C] = 0.800;
+ int22_ar[U][G][A][A][C][U][G][C] = 2.000;
+ int22_ar[U][G][A][A][G][A][G][C] = 0.100;
+ int22_ar[U][G][A][A][G][C][G][C] = 0.100;
+ int22_ar[U][G][A][A][G][G][G][C] = -0.900;
+ int22_ar[U][G][A][A][G][U][G][C] = 2.000;
+ int22_ar[U][G][A][A][U][A][G][C] = 2.000;
+ int22_ar[U][G][A][A][U][C][G][C] = 2.000;
+ int22_ar[U][G][A][A][U][G][G][C] = 2.000;
+ int22_ar[U][G][A][A][U][U][G][C] = 2.000;
+ int22_ar[U][G][A][C][A][A][G][C] = 1.800;
+ int22_ar[U][G][A][C][A][C][G][C] = 1.800;
+ int22_ar[U][G][A][C][A][G][G][C] = 0.800;
+ int22_ar[U][G][A][C][A][U][G][C] = 2.000;
+ int22_ar[U][G][A][C][C][A][G][C] = 2.500;
+ int22_ar[U][G][A][C][C][C][G][C] = 1.900;
+ int22_ar[U][G][A][C][C][G][G][C] = 1.800;
+ int22_ar[U][G][A][C][C][U][G][C] = 2.000;
+ int22_ar[U][G][A][C][G][A][G][C] = 2.000;
+ int22_ar[U][G][A][C][G][C][G][C] = 2.000;
+ int22_ar[U][G][A][C][G][G][G][C] = 2.000;
+ int22_ar[U][G][A][C][G][U][G][C] = 2.000;
+ int22_ar[U][G][A][C][U][A][G][C] = 1.500;
+ int22_ar[U][G][A][C][U][C][G][C] = 0.900;
+ int22_ar[U][G][A][C][U][G][G][C] = 0.900;
+ int22_ar[U][G][A][C][U][U][G][C] = 2.000;
+ int22_ar[U][G][A][G][A][A][G][C] = 0.700;
+ int22_ar[U][G][A][G][A][C][G][C] = 0.700;
+ int22_ar[U][G][A][G][A][G][G][C] = -0.300;
+ int22_ar[U][G][A][G][A][U][G][C] = 2.000;
+ int22_ar[U][G][A][G][C][A][G][C] = 2.000;
+ int22_ar[U][G][A][G][C][C][G][C] = 2.000;
+ int22_ar[U][G][A][G][C][G][G][C] = 2.000;
+ int22_ar[U][G][A][G][C][U][G][C] = 2.000;
+ int22_ar[U][G][A][G][G][A][G][C] = 1.800;
+ int22_ar[U][G][A][G][G][C][G][C] = 1.800;
+ int22_ar[U][G][A][G][G][G][G][C] = 0.700;
+ int22_ar[U][G][A][G][G][U][G][C] = 2.000;
+ int22_ar[U][G][A][G][U][A][G][C] = 0.000;
+ int22_ar[U][G][A][G][U][C][G][C] = -1.000;
+ int22_ar[U][G][A][G][U][G][G][C] = -0.300;
+ int22_ar[U][G][A][G][U][U][G][C] = 2.000;
+ int22_ar[U][G][A][U][A][A][G][C] = 2.000;
+ int22_ar[U][G][A][U][A][C][G][C] = 2.000;
+ int22_ar[U][G][A][U][A][G][G][C] = 2.000;
+ int22_ar[U][G][A][U][A][U][G][C] = 2.000;
+ int22_ar[U][G][A][U][C][A][G][C] = 2.500;
+ int22_ar[U][G][A][U][C][C][G][C] = 1.900;
+ int22_ar[U][G][A][U][C][G][G][C] = 1.900;
+ int22_ar[U][G][A][U][C][U][G][C] = 2.000;
+ int22_ar[U][G][A][U][G][A][G][C] = 0.400;
+ int22_ar[U][G][A][U][G][C][G][C] = -0.600;
+ int22_ar[U][G][A][U][G][G][G][C] = 0.100;
+ int22_ar[U][G][A][U][G][U][G][C] = 2.000;
+ int22_ar[U][G][A][U][U][A][G][C] = 2.100;
+ int22_ar[U][G][A][U][U][C][G][C] = 1.100;
+ int22_ar[U][G][A][U][U][G][G][C] = 1.900;
+ int22_ar[U][G][A][U][U][U][G][C] = 2.000;
+ int22_ar[U][G][C][A][A][A][G][C] = 1.700;
+ int22_ar[U][G][C][A][A][C][G][C] = 2.700;
+ int22_ar[U][G][C][A][A][G][G][C] = 2.000;
+ int22_ar[U][G][C][A][A][U][G][C] = 2.400;
+ int22_ar[U][G][C][A][C][A][G][C] = 1.400;
+ int22_ar[U][G][C][A][C][C][G][C] = 1.900;
+ int22_ar[U][G][C][A][C][G][G][C] = 2.000;
+ int22_ar[U][G][C][A][C][U][G][C] = 1.600;
+ int22_ar[U][G][C][A][G][A][G][C] = -0.300;
+ int22_ar[U][G][C][A][G][C][G][C] = 1.100;
+ int22_ar[U][G][C][A][G][G][G][C] = 2.000;
+ int22_ar[U][G][C][A][G][U][G][C] = 0.800;
+ int22_ar[U][G][C][A][U][A][G][C] = 2.000;
+ int22_ar[U][G][C][A][U][C][G][C] = 2.000;
+ int22_ar[U][G][C][A][U][G][G][C] = 2.000;
+ int22_ar[U][G][C][A][U][U][G][C] = 2.000;
+ int22_ar[U][G][C][C][A][A][G][C] = 1.400;
+ int22_ar[U][G][C][C][A][C][G][C] = 1.800;
+ int22_ar[U][G][C][C][A][G][G][C] = 2.000;
+ int22_ar[U][G][C][C][A][U][G][C] = 1.500;
+ int22_ar[U][G][C][C][C][A][G][C] = 1.400;
+ int22_ar[U][G][C][C][C][C][G][C] = 1.900;
+ int22_ar[U][G][C][C][C][G][G][C] = 2.000;
+ int22_ar[U][G][C][C][C][U][G][C] = 1.600;
+ int22_ar[U][G][C][C][G][A][G][C] = 2.000;
+ int22_ar[U][G][C][C][G][C][G][C] = 2.000;
+ int22_ar[U][G][C][C][G][G][G][C] = 2.000;
+ int22_ar[U][G][C][C][G][U][G][C] = 2.000;
+ int22_ar[U][G][C][C][U][A][G][C] = 0.400;
+ int22_ar[U][G][C][C][U][C][G][C] = 0.900;
+ int22_ar[U][G][C][C][U][G][G][C] = 2.000;
+ int22_ar[U][G][C][C][U][U][G][C] = 0.600;
+ int22_ar[U][G][C][G][A][A][G][C] = 0.300;
+ int22_ar[U][G][C][G][A][C][G][C] = 1.700;
+ int22_ar[U][G][C][G][A][G][G][C] = 2.000;
+ int22_ar[U][G][C][G][A][U][G][C] = 1.400;
+ int22_ar[U][G][C][G][C][A][G][C] = 2.000;
+ int22_ar[U][G][C][G][C][C][G][C] = 2.000;
+ int22_ar[U][G][C][G][C][G][G][C] = 2.000;
+ int22_ar[U][G][C][G][C][U][G][C] = 2.000;
+ int22_ar[U][G][C][G][G][A][G][C] = 1.300;
+ int22_ar[U][G][C][G][G][C][G][C] = 2.400;
+ int22_ar[U][G][C][G][G][G][G][C] = 2.000;
+ int22_ar[U][G][C][G][G][U][G][C] = 2.100;
+ int22_ar[U][G][C][G][U][A][G][C] = -1.500;
+ int22_ar[U][G][C][G][U][C][G][C] = 0.000;
+ int22_ar[U][G][C][G][U][G][G][C] = 2.000;
+ int22_ar[U][G][C][G][U][U][G][C] = -0.300;
+ int22_ar[U][G][C][U][A][A][G][C] = 2.000;
+ int22_ar[U][G][C][U][A][C][G][C] = 2.000;
+ int22_ar[U][G][C][U][A][G][G][C] = 2.000;
+ int22_ar[U][G][C][U][A][U][G][C] = 2.000;
+ int22_ar[U][G][C][U][C][A][G][C] = 1.500;
+ int22_ar[U][G][C][U][C][C][G][C] = 1.900;
+ int22_ar[U][G][C][U][C][G][G][C] = 2.000;
+ int22_ar[U][G][C][U][C][U][G][C] = 1.600;
+ int22_ar[U][G][C][U][G][A][G][C] = -1.100;
+ int22_ar[U][G][C][U][G][C][G][C] = 0.400;
+ int22_ar[U][G][C][U][G][G][G][C] = 2.000;
+ int22_ar[U][G][C][U][G][U][G][C] = 0.100;
+ int22_ar[U][G][C][U][U][A][G][C] = 0.700;
+ int22_ar[U][G][C][U][U][C][G][C] = 1.100;
+ int22_ar[U][G][C][U][U][G][G][C] = 2.000;
+ int22_ar[U][G][C][U][U][U][G][C] = 0.800;
+ int22_ar[U][G][G][A][A][A][G][C] = 1.100;
+ int22_ar[U][G][G][A][A][C][G][C] = 2.000;
+ int22_ar[U][G][G][A][A][G][G][C] = 1.500;
+ int22_ar[U][G][G][A][A][U][G][C] = 1.600;
+ int22_ar[U][G][G][A][C][A][G][C] = 0.800;
+ int22_ar[U][G][G][A][C][C][G][C] = 2.000;
+ int22_ar[U][G][G][A][C][G][G][C] = 1.200;
+ int22_ar[U][G][G][A][C][U][G][C] = 0.300;
+ int22_ar[U][G][G][A][G][A][G][C] = -0.900;
+ int22_ar[U][G][G][A][G][C][G][C] = 2.000;
+ int22_ar[U][G][G][A][G][G][G][C] = -0.500;
+ int22_ar[U][G][G][A][G][U][G][C] = 0.400;
+ int22_ar[U][G][G][A][U][A][G][C] = 2.000;
+ int22_ar[U][G][G][A][U][C][G][C] = 2.000;
+ int22_ar[U][G][G][A][U][G][G][C] = 2.000;
+ int22_ar[U][G][G][A][U][U][G][C] = 2.000;
+ int22_ar[U][G][G][C][A][A][G][C] = 0.800;
+ int22_ar[U][G][G][C][A][C][G][C] = 2.000;
+ int22_ar[U][G][G][C][A][G][G][C] = 1.200;
+ int22_ar[U][G][G][C][A][U][G][C] = 0.300;
+ int22_ar[U][G][G][C][C][A][G][C] = 1.800;
+ int22_ar[U][G][G][C][C][C][G][C] = 2.000;
+ int22_ar[U][G][G][C][C][G][G][C] = 1.800;
+ int22_ar[U][G][G][C][C][U][G][C] = 1.300;
+ int22_ar[U][G][G][C][G][A][G][C] = 2.000;
+ int22_ar[U][G][G][C][G][C][G][C] = 2.000;
+ int22_ar[U][G][G][C][G][G][G][C] = 2.000;
+ int22_ar[U][G][G][C][G][U][G][C] = 2.000;
+ int22_ar[U][G][G][C][U][A][G][C] = 0.900;
+ int22_ar[U][G][G][C][U][C][G][C] = 2.000;
+ int22_ar[U][G][G][C][U][G][G][C] = 0.800;
+ int22_ar[U][G][G][C][U][U][G][C] = 0.400;
+ int22_ar[U][G][G][G][A][A][G][C] = -0.300;
+ int22_ar[U][G][G][G][A][C][G][C] = 2.000;
+ int22_ar[U][G][G][G][A][G][G][C] = 0.100;
+ int22_ar[U][G][G][G][A][U][G][C] = 1.000;
+ int22_ar[U][G][G][G][C][A][G][C] = 2.000;
+ int22_ar[U][G][G][G][C][C][G][C] = 2.000;
+ int22_ar[U][G][G][G][C][G][G][C] = 2.000;
+ int22_ar[U][G][G][G][C][U][G][C] = 2.000;
+ int22_ar[U][G][G][G][G][A][G][C] = 0.700;
+ int22_ar[U][G][G][G][G][C][G][C] = 2.000;
+ int22_ar[U][G][G][G][G][G][G][C] = 1.100;
+ int22_ar[U][G][G][G][G][U][G][C] = 1.200;
+ int22_ar[U][G][G][G][U][A][G][C] = -0.300;
+ int22_ar[U][G][G][G][U][C][G][C] = 2.000;
+ int22_ar[U][G][G][G][U][G][G][C] = -0.700;
+ int22_ar[U][G][G][G][U][U][G][C] = -2.600;
+ int22_ar[U][G][G][U][A][A][G][C] = 2.000;
+ int22_ar[U][G][G][U][A][C][G][C] = 2.000;
+ int22_ar[U][G][G][U][A][G][G][C] = 2.000;
+ int22_ar[U][G][G][U][A][U][G][C] = 2.000;
+ int22_ar[U][G][G][U][C][A][G][C] = 1.900;
+ int22_ar[U][G][G][U][C][C][G][C] = 2.000;
+ int22_ar[U][G][G][U][C][G][G][C] = 1.900;
+ int22_ar[U][G][G][U][C][U][G][C] = 1.400;
+ int22_ar[U][G][G][U][G][A][G][C] = 0.100;
+ int22_ar[U][G][G][U][G][C][G][C] = 2.000;
+ int22_ar[U][G][G][U][G][G][G][C] = -0.300;
+ int22_ar[U][G][G][U][G][U][G][C] = -2.200;
+ int22_ar[U][G][G][U][U][A][G][C] = 1.900;
+ int22_ar[U][G][G][U][U][C][G][C] = 2.000;
+ int22_ar[U][G][G][U][U][G][G][C] = 1.500;
+ int22_ar[U][G][G][U][U][U][G][C] = 1.400;
+ int22_ar[U][G][U][A][A][A][G][C] = 2.000;
+ int22_ar[U][G][U][A][A][C][G][C] = 2.700;
+ int22_ar[U][G][U][A][A][G][G][C] = 0.300;
+ int22_ar[U][G][U][A][A][U][G][C] = 2.300;
+ int22_ar[U][G][U][A][C][A][G][C] = 2.000;
+ int22_ar[U][G][U][A][C][C][G][C] = 1.900;
+ int22_ar[U][G][U][A][C][G][G][C] = -0.900;
+ int22_ar[U][G][U][A][C][U][G][C] = 1.000;
+ int22_ar[U][G][U][A][G][A][G][C] = 2.000;
+ int22_ar[U][G][U][A][G][C][G][C] = 1.100;
+ int22_ar[U][G][U][A][G][G][G][C] = -0.900;
+ int22_ar[U][G][U][A][G][U][G][C] = 1.100;
+ int22_ar[U][G][U][A][U][A][G][C] = 2.000;
+ int22_ar[U][G][U][A][U][C][G][C] = 2.000;
+ int22_ar[U][G][U][A][U][G][G][C] = 2.000;
+ int22_ar[U][G][U][A][U][U][G][C] = 2.000;
+ int22_ar[U][G][U][C][A][A][G][C] = 2.000;
+ int22_ar[U][G][U][C][A][C][G][C] = 1.800;
+ int22_ar[U][G][U][C][A][G][G][C] = -1.000;
+ int22_ar[U][G][U][C][A][U][G][C] = 1.000;
+ int22_ar[U][G][U][C][C][A][G][C] = 2.000;
+ int22_ar[U][G][U][C][C][C][G][C] = 1.900;
+ int22_ar[U][G][U][C][C][G][G][C] = 0.100;
+ int22_ar[U][G][U][C][C][U][G][C] = 1.000;
+ int22_ar[U][G][U][C][G][A][G][C] = 2.000;
+ int22_ar[U][G][U][C][G][C][G][C] = 2.000;
+ int22_ar[U][G][U][C][G][G][G][C] = 2.000;
+ int22_ar[U][G][U][C][G][U][G][C] = 2.000;
+ int22_ar[U][G][U][C][U][A][G][C] = 2.000;
+ int22_ar[U][G][U][C][U][C][G][C] = 0.900;
+ int22_ar[U][G][U][C][U][G][G][C] = -0.900;
+ int22_ar[U][G][U][C][U][U][G][C] = 0.000;
+ int22_ar[U][G][U][G][A][A][G][C] = 2.000;
+ int22_ar[U][G][U][G][A][C][G][C] = 1.700;
+ int22_ar[U][G][U][G][A][G][G][C] = -0.300;
+ int22_ar[U][G][U][G][A][U][G][C] = 1.700;
+ int22_ar[U][G][U][G][C][A][G][C] = 2.000;
+ int22_ar[U][G][U][G][C][C][G][C] = 2.000;
+ int22_ar[U][G][U][G][C][G][G][C] = 2.000;
+ int22_ar[U][G][U][G][C][U][G][C] = 2.000;
+ int22_ar[U][G][U][G][G][A][G][C] = 2.000;
+ int22_ar[U][G][U][G][G][C][G][C] = 2.400;
+ int22_ar[U][G][U][G][G][G][G][C] = 0.000;
+ int22_ar[U][G][U][G][G][U][G][C] = 1.900;
+ int22_ar[U][G][U][G][U][A][G][C] = 2.000;
+ int22_ar[U][G][U][G][U][C][G][C] = 0.000;
+ int22_ar[U][G][U][G][U][G][G][C] = -3.900;
+ int22_ar[U][G][U][G][U][U][G][C] = -0.100;
+ int22_ar[U][G][U][U][A][A][G][C] = 2.000;
+ int22_ar[U][G][U][U][A][C][G][C] = 2.000;
+ int22_ar[U][G][U][U][A][G][G][C] = 2.000;
+ int22_ar[U][G][U][U][A][U][G][C] = 2.000;
+ int22_ar[U][G][U][U][C][A][G][C] = 2.000;
+ int22_ar[U][G][U][U][C][C][G][C] = 1.900;
+ int22_ar[U][G][U][U][C][G][G][C] = 0.100;
+ int22_ar[U][G][U][U][C][U][G][C] = 1.100;
+ int22_ar[U][G][U][U][G][A][G][C] = 2.000;
+ int22_ar[U][G][U][U][G][C][G][C] = 0.400;
+ int22_ar[U][G][U][U][G][G][G][C] = -3.500;
+ int22_ar[U][G][U][U][G][U][G][C] = 0.300;
+ int22_ar[U][G][U][U][U][A][G][C] = 2.000;
+ int22_ar[U][G][U][U][U][C][G][C] = 1.100;
+ int22_ar[U][G][U][U][U][G][G][C] = 0.100;
+ int22_ar[U][G][U][U][U][U][G][C] = 0.300;
+ int22_ar[U][G][A][A][A][A][G][U] = 2.800;
+ int22_ar[U][G][A][A][A][C][G][U] = 2.800;
+ int22_ar[U][G][A][A][A][G][G][U] = 1.700;
+ int22_ar[U][G][A][A][A][U][G][U] = 2.000;
+ int22_ar[U][G][A][A][C][A][G][U] = 2.500;
+ int22_ar[U][G][A][A][C][C][G][U] = 2.500;
+ int22_ar[U][G][A][A][C][G][G][U] = 1.500;
+ int22_ar[U][G][A][A][C][U][G][U] = 2.000;
+ int22_ar[U][G][A][A][G][A][G][U] = 1.500;
+ int22_ar[U][G][A][A][G][C][G][U] = 1.500;
+ int22_ar[U][G][A][A][G][G][G][U] = 0.500;
+ int22_ar[U][G][A][A][G][U][G][U] = 2.000;
+ int22_ar[U][G][A][A][U][A][G][U] = 2.000;
+ int22_ar[U][G][A][A][U][C][G][U] = 2.000;
+ int22_ar[U][G][A][A][U][G][G][U] = 2.000;
+ int22_ar[U][G][A][A][U][U][G][U] = 2.000;
+ int22_ar[U][G][A][C][A][A][G][U] = 2.600;
+ int22_ar[U][G][A][C][A][C][G][U] = 2.600;
+ int22_ar[U][G][A][C][A][G][G][U] = 1.600;
+ int22_ar[U][G][A][C][A][U][G][U] = 2.000;
+ int22_ar[U][G][A][C][C][A][G][U] = 3.100;
+ int22_ar[U][G][A][C][C][C][G][U] = 2.500;
+ int22_ar[U][G][A][C][C][G][G][U] = 2.400;
+ int22_ar[U][G][A][C][C][U][G][U] = 2.000;
+ int22_ar[U][G][A][C][G][A][G][U] = 2.000;
+ int22_ar[U][G][A][C][G][C][G][U] = 2.000;
+ int22_ar[U][G][A][C][G][G][G][U] = 2.000;
+ int22_ar[U][G][A][C][G][U][G][U] = 2.000;
+ int22_ar[U][G][A][C][U][A][G][U] = 3.100;
+ int22_ar[U][G][A][C][U][C][G][U] = 2.500;
+ int22_ar[U][G][A][C][U][G][G][U] = 2.400;
+ int22_ar[U][G][A][C][U][U][G][U] = 2.000;
+ int22_ar[U][G][A][G][A][A][G][U] = 1.500;
+ int22_ar[U][G][A][G][A][C][G][U] = 1.500;
+ int22_ar[U][G][A][G][A][G][G][U] = 0.500;
+ int22_ar[U][G][A][G][A][U][G][U] = 2.000;
+ int22_ar[U][G][A][G][C][A][G][U] = 2.000;
+ int22_ar[U][G][A][G][C][C][G][U] = 2.000;
+ int22_ar[U][G][A][G][C][G][G][U] = 2.000;
+ int22_ar[U][G][A][G][C][U][G][U] = 2.000;
+ int22_ar[U][G][A][G][G][A][G][U] = 2.100;
+ int22_ar[U][G][A][G][G][C][G][U] = 2.100;
+ int22_ar[U][G][A][G][G][G][G][U] = 1.000;
+ int22_ar[U][G][A][G][G][U][G][U] = 2.000;
+ int22_ar[U][G][A][G][U][A][G][U] = 1.300;
+ int22_ar[U][G][A][G][U][C][G][U] = 0.300;
+ int22_ar[U][G][A][G][U][G][G][U] = 1.100;
+ int22_ar[U][G][A][G][U][U][G][U] = 2.000;
+ int22_ar[U][G][A][U][A][A][G][U] = 2.000;
+ int22_ar[U][G][A][U][A][C][G][U] = 2.000;
+ int22_ar[U][G][A][U][A][G][G][U] = 2.000;
+ int22_ar[U][G][A][U][A][U][G][U] = 2.000;
+ int22_ar[U][G][A][U][C][A][G][U] = 3.100;
+ int22_ar[U][G][A][U][C][C][G][U] = 2.500;
+ int22_ar[U][G][A][U][C][G][G][U] = 2.400;
+ int22_ar[U][G][A][U][C][U][G][U] = 2.000;
+ int22_ar[U][G][A][U][G][A][G][U] = 2.300;
+ int22_ar[U][G][A][U][G][C][G][U] = 1.300;
+ int22_ar[U][G][A][U][G][G][G][U] = 2.100;
+ int22_ar[U][G][A][U][G][U][G][U] = 2.000;
+ int22_ar[U][G][A][U][U][A][G][U] = 2.700;
+ int22_ar[U][G][A][U][U][C][G][U] = 1.700;
+ int22_ar[U][G][A][U][U][G][G][U] = 2.400;
+ int22_ar[U][G][A][U][U][U][G][U] = 2.000;
+ int22_ar[U][G][C][A][A][A][G][U] = 2.300;
+ int22_ar[U][G][C][A][A][C][G][U] = 3.400;
+ int22_ar[U][G][C][A][A][G][G][U] = 2.000;
+ int22_ar[U][G][C][A][A][U][G][U] = 3.100;
+ int22_ar[U][G][C][A][C][A][G][U] = 2.100;
+ int22_ar[U][G][C][A][C][C][G][U] = 2.500;
+ int22_ar[U][G][C][A][C][G][G][U] = 2.000;
+ int22_ar[U][G][C][A][C][U][G][U] = 2.200;
+ int22_ar[U][G][C][A][G][A][G][U] = 1.100;
+ int22_ar[U][G][C][A][G][C][G][U] = 2.500;
+ int22_ar[U][G][C][A][G][G][G][U] = 2.000;
+ int22_ar[U][G][C][A][G][U][G][U] = 2.200;
+ int22_ar[U][G][C][A][U][A][G][U] = 2.000;
+ int22_ar[U][G][C][A][U][C][G][U] = 2.000;
+ int22_ar[U][G][C][A][U][G][G][U] = 2.000;
+ int22_ar[U][G][C][A][U][U][G][U] = 2.000;
+ int22_ar[U][G][C][C][A][A][G][U] = 2.200;
+ int22_ar[U][G][C][C][A][C][G][U] = 2.600;
+ int22_ar[U][G][C][C][A][G][G][U] = 2.000;
+ int22_ar[U][G][C][C][A][U][G][U] = 2.300;
+ int22_ar[U][G][C][C][C][A][G][U] = 2.000;
+ int22_ar[U][G][C][C][C][C][G][U] = 2.500;
+ int22_ar[U][G][C][C][C][G][G][U] = 2.000;
+ int22_ar[U][G][C][C][C][U][G][U] = 2.200;
+ int22_ar[U][G][C][C][G][A][G][U] = 2.000;
+ int22_ar[U][G][C][C][G][C][G][U] = 2.000;
+ int22_ar[U][G][C][C][G][G][G][U] = 2.000;
+ int22_ar[U][G][C][C][G][U][G][U] = 2.000;
+ int22_ar[U][G][C][C][U][A][G][U] = 2.000;
+ int22_ar[U][G][C][C][U][C][G][U] = 2.500;
+ int22_ar[U][G][C][C][U][G][G][U] = 2.000;
+ int22_ar[U][G][C][C][U][U][G][U] = 2.200;
+ int22_ar[U][G][C][G][A][A][G][U] = 1.100;
+ int22_ar[U][G][C][G][A][C][G][U] = 2.500;
+ int22_ar[U][G][C][G][A][G][G][U] = 2.000;
+ int22_ar[U][G][C][G][A][U][G][U] = 2.200;
+ int22_ar[U][G][C][G][C][A][G][U] = 2.000;
+ int22_ar[U][G][C][G][C][C][G][U] = 2.000;
+ int22_ar[U][G][C][G][C][G][G][U] = 2.000;
+ int22_ar[U][G][C][G][C][U][G][U] = 2.000;
+ int22_ar[U][G][C][G][G][A][G][U] = 1.600;
+ int22_ar[U][G][C][G][G][C][G][U] = 2.700;
+ int22_ar[U][G][C][G][G][G][G][U] = 2.000;
+ int22_ar[U][G][C][G][G][U][G][U] = 2.400;
+ int22_ar[U][G][C][G][U][A][G][U] = -0.100;
+ int22_ar[U][G][C][G][U][C][G][U] = 1.300;
+ int22_ar[U][G][C][G][U][G][G][U] = 2.000;
+ int22_ar[U][G][C][G][U][U][G][U] = 1.000;
+ int22_ar[U][G][C][U][A][A][G][U] = 2.000;
+ int22_ar[U][G][C][U][A][C][G][U] = 2.000;
+ int22_ar[U][G][C][U][A][G][G][U] = 2.000;
+ int22_ar[U][G][C][U][A][U][G][U] = 2.000;
+ int22_ar[U][G][C][U][C][A][G][U] = 2.000;
+ int22_ar[U][G][C][U][C][C][G][U] = 2.500;
+ int22_ar[U][G][C][U][C][G][G][U] = 2.000;
+ int22_ar[U][G][C][U][C][U][G][U] = 2.200;
+ int22_ar[U][G][C][U][G][A][G][U] = 0.900;
+ int22_ar[U][G][C][U][G][C][G][U] = 2.300;
+ int22_ar[U][G][C][U][G][G][G][U] = 2.000;
+ int22_ar[U][G][C][U][G][U][G][U] = 2.000;
+ int22_ar[U][G][C][U][U][A][G][U] = 1.200;
+ int22_ar[U][G][C][U][U][C][G][U] = 1.700;
+ int22_ar[U][G][C][U][U][G][G][U] = 2.000;
+ int22_ar[U][G][C][U][U][U][G][U] = 1.400;
+ int22_ar[U][G][G][A][A][A][G][U] = 1.700;
+ int22_ar[U][G][G][A][A][C][G][U] = 2.000;
+ int22_ar[U][G][G][A][A][G][G][U] = 2.100;
+ int22_ar[U][G][G][A][A][U][G][U] = 2.200;
+ int22_ar[U][G][G][A][C][A][G][U] = 1.500;
+ int22_ar[U][G][G][A][C][C][G][U] = 2.000;
+ int22_ar[U][G][G][A][C][G][G][U] = 1.900;
+ int22_ar[U][G][G][A][C][U][G][U] = 1.000;
+ int22_ar[U][G][G][A][G][A][G][U] = 0.500;
+ int22_ar[U][G][G][A][G][C][G][U] = 2.000;
+ int22_ar[U][G][G][A][G][G][G][U] = 0.900;
+ int22_ar[U][G][G][A][G][U][G][U] = 1.800;
+ int22_ar[U][G][G][A][U][A][G][U] = 2.000;
+ int22_ar[U][G][G][A][U][C][G][U] = 2.000;
+ int22_ar[U][G][G][A][U][G][G][U] = 2.000;
+ int22_ar[U][G][G][A][U][U][G][U] = 2.000;
+ int22_ar[U][G][G][C][A][A][G][U] = 1.600;
+ int22_ar[U][G][G][C][A][C][G][U] = 2.000;
+ int22_ar[U][G][G][C][A][G][G][U] = 2.000;
+ int22_ar[U][G][G][C][A][U][G][U] = 1.100;
+ int22_ar[U][G][G][C][C][A][G][U] = 2.400;
+ int22_ar[U][G][G][C][C][C][G][U] = 2.000;
+ int22_ar[U][G][G][C][C][G][G][U] = 2.400;
+ int22_ar[U][G][G][C][C][U][G][U] = 1.900;
+ int22_ar[U][G][G][C][G][A][G][U] = 2.000;
+ int22_ar[U][G][G][C][G][C][G][U] = 2.000;
+ int22_ar[U][G][G][C][G][G][G][U] = 2.000;
+ int22_ar[U][G][G][C][G][U][G][U] = 2.000;
+ int22_ar[U][G][G][C][U][A][G][U] = 2.400;
+ int22_ar[U][G][G][C][U][C][G][U] = 2.000;
+ int22_ar[U][G][G][C][U][G][G][U] = 2.400;
+ int22_ar[U][G][G][C][U][U][G][U] = 1.900;
+ int22_ar[U][G][G][G][A][A][G][U] = 0.500;
+ int22_ar[U][G][G][G][A][C][G][U] = 2.000;
+ int22_ar[U][G][G][G][A][G][G][U] = 0.900;
+ int22_ar[U][G][G][G][A][U][G][U] = 1.800;
+ int22_ar[U][G][G][G][C][A][G][U] = 2.000;
+ int22_ar[U][G][G][G][C][C][G][U] = 2.000;
+ int22_ar[U][G][G][G][C][G][G][U] = 2.000;
+ int22_ar[U][G][G][G][C][U][G][U] = 2.000;
+ int22_ar[U][G][G][G][G][A][G][U] = 1.000;
+ int22_ar[U][G][G][G][G][C][G][U] = 2.000;
+ int22_ar[U][G][G][G][G][G][G][U] = 1.400;
+ int22_ar[U][G][G][G][G][U][G][U] = 1.500;
+ int22_ar[U][G][G][G][U][A][G][U] = 1.100;
+ int22_ar[U][G][G][G][U][C][G][U] = 2.000;
+ int22_ar[U][G][G][G][U][G][G][U] = 0.700;
+ int22_ar[U][G][G][G][U][U][G][U] = -1.200;
+ int22_ar[U][G][G][U][A][A][G][U] = 2.000;
+ int22_ar[U][G][G][U][A][C][G][U] = 2.000;
+ int22_ar[U][G][G][U][A][G][G][U] = 2.000;
+ int22_ar[U][G][G][U][A][U][G][U] = 2.000;
+ int22_ar[U][G][G][U][C][A][G][U] = 2.400;
+ int22_ar[U][G][G][U][C][C][G][U] = 2.000;
+ int22_ar[U][G][G][U][C][G][G][U] = 2.400;
+ int22_ar[U][G][G][U][C][U][G][U] = 1.900;
+ int22_ar[U][G][G][U][G][A][G][U] = 2.100;
+ int22_ar[U][G][G][U][G][C][G][U] = 2.000;
+ int22_ar[U][G][G][U][G][G][G][U] = 1.700;
+ int22_ar[U][G][G][U][G][U][G][U] = -0.200;
+ int22_ar[U][G][G][U][U][A][G][U] = 2.400;
+ int22_ar[U][G][G][U][U][C][G][U] = 2.000;
+ int22_ar[U][G][G][U][U][G][G][U] = 2.000;
+ int22_ar[U][G][G][U][U][U][G][U] = 1.900;
+ int22_ar[U][G][U][A][A][A][G][U] = 2.000;
+ int22_ar[U][G][U][A][A][C][G][U] = 3.400;
+ int22_ar[U][G][U][A][A][G][G][U] = 1.000;
+ int22_ar[U][G][U][A][A][U][G][U] = 2.900;
+ int22_ar[U][G][U][A][C][A][G][U] = 2.000;
+ int22_ar[U][G][U][A][C][C][G][U] = 2.500;
+ int22_ar[U][G][U][A][C][G][G][U] = -0.300;
+ int22_ar[U][G][U][A][C][U][G][U] = 1.700;
+ int22_ar[U][G][U][A][G][A][G][U] = 2.000;
+ int22_ar[U][G][U][A][G][C][G][U] = 2.500;
+ int22_ar[U][G][U][A][G][G][G][U] = 0.500;
+ int22_ar[U][G][U][A][G][U][G][U] = 2.500;
+ int22_ar[U][G][U][A][U][A][G][U] = 2.000;
+ int22_ar[U][G][U][A][U][C][G][U] = 2.000;
+ int22_ar[U][G][U][A][U][G][G][U] = 2.000;
+ int22_ar[U][G][U][A][U][U][G][U] = 2.000;
+ int22_ar[U][G][U][C][A][A][G][U] = 2.000;
+ int22_ar[U][G][U][C][A][C][G][U] = 2.600;
+ int22_ar[U][G][U][C][A][G][G][U] = -0.200;
+ int22_ar[U][G][U][C][A][U][G][U] = 1.800;
+ int22_ar[U][G][U][C][C][A][G][U] = 2.000;
+ int22_ar[U][G][U][C][C][C][G][U] = 2.500;
+ int22_ar[U][G][U][C][C][G][G][U] = 0.700;
+ int22_ar[U][G][U][C][C][U][G][U] = 1.600;
+ int22_ar[U][G][U][C][G][A][G][U] = 2.000;
+ int22_ar[U][G][U][C][G][C][G][U] = 2.000;
+ int22_ar[U][G][U][C][G][G][G][U] = 2.000;
+ int22_ar[U][G][U][C][G][U][G][U] = 2.000;
+ int22_ar[U][G][U][C][U][A][G][U] = 2.000;
+ int22_ar[U][G][U][C][U][C][G][U] = 2.500;
+ int22_ar[U][G][U][C][U][G][G][U] = 0.700;
+ int22_ar[U][G][U][C][U][U][G][U] = 1.600;
+ int22_ar[U][G][U][G][A][A][G][U] = 2.000;
+ int22_ar[U][G][U][G][A][C][G][U] = 2.500;
+ int22_ar[U][G][U][G][A][G][G][U] = 0.500;
+ int22_ar[U][G][U][G][A][U][G][U] = 2.500;
+ int22_ar[U][G][U][G][C][A][G][U] = 2.000;
+ int22_ar[U][G][U][G][C][C][G][U] = 2.000;
+ int22_ar[U][G][U][G][C][G][G][U] = 2.000;
+ int22_ar[U][G][U][G][C][U][G][U] = 2.000;
+ int22_ar[U][G][U][G][G][A][G][U] = 2.000;
+ int22_ar[U][G][U][G][G][C][G][U] = 2.700;
+ int22_ar[U][G][U][G][G][G][G][U] = 0.300;
+ int22_ar[U][G][U][G][G][U][G][U] = 2.200;
+ int22_ar[U][G][U][G][U][A][G][U] = 2.000;
+ int22_ar[U][G][U][G][U][C][G][U] = 1.300;
+ int22_ar[U][G][U][G][U][G][G][U] = -2.500;
+ int22_ar[U][G][U][G][U][U][G][U] = 1.300;
+ int22_ar[U][G][U][U][A][A][G][U] = 2.000;
+ int22_ar[U][G][U][U][A][C][G][U] = 2.000;
+ int22_ar[U][G][U][U][A][G][G][U] = 2.000;
+ int22_ar[U][G][U][U][A][U][G][U] = 2.000;
+ int22_ar[U][G][U][U][C][A][G][U] = 2.000;
+ int22_ar[U][G][U][U][C][C][G][U] = 2.500;
+ int22_ar[U][G][U][U][C][G][G][U] = 0.700;
+ int22_ar[U][G][U][U][C][U][G][U] = 1.600;
+ int22_ar[U][G][U][U][G][A][G][U] = 2.000;
+ int22_ar[U][G][U][U][G][C][G][U] = 2.300;
+ int22_ar[U][G][U][U][G][G][G][U] = -1.500;
+ int22_ar[U][G][U][U][G][U][G][U] = 2.300;
+ int22_ar[U][G][U][U][U][A][G][U] = 2.000;
+ int22_ar[U][G][U][U][U][C][G][U] = 1.700;
+ int22_ar[U][G][U][U][U][G][G][U] = 0.700;
+ int22_ar[U][G][U][U][U][U][G][U] = 0.800;
+ int22_ar[U][G][A][A][A][A][U][A] = 2.800;
+ int22_ar[U][G][A][A][A][C][U][A] = 2.800;
+ int22_ar[U][G][A][A][A][G][U][A] = 1.700;
+ int22_ar[U][G][A][A][A][U][U][A] = 2.000;
+ int22_ar[U][G][A][A][C][A][U][A] = 2.300;
+ int22_ar[U][G][A][A][C][C][U][A] = 2.300;
+ int22_ar[U][G][A][A][C][G][U][A] = 1.300;
+ int22_ar[U][G][A][A][C][U][U][A] = 2.000;
+ int22_ar[U][G][A][A][G][A][U][A] = 1.700;
+ int22_ar[U][G][A][A][G][C][U][A] = 1.700;
+ int22_ar[U][G][A][A][G][G][U][A] = 0.700;
+ int22_ar[U][G][A][A][G][U][U][A] = 2.000;
+ int22_ar[U][G][A][A][U][A][U][A] = 2.000;
+ int22_ar[U][G][A][A][U][C][U][A] = 2.000;
+ int22_ar[U][G][A][A][U][G][U][A] = 2.000;
+ int22_ar[U][G][A][A][U][U][U][A] = 2.000;
+ int22_ar[U][G][A][C][A][A][U][A] = 2.800;
+ int22_ar[U][G][A][C][A][C][U][A] = 2.800;
+ int22_ar[U][G][A][C][A][G][U][A] = 1.700;
+ int22_ar[U][G][A][C][A][U][U][A] = 2.000;
+ int22_ar[U][G][A][C][C][A][U][A] = 3.400;
+ int22_ar[U][G][A][C][C][C][U][A] = 2.800;
+ int22_ar[U][G][A][C][C][G][U][A] = 2.700;
+ int22_ar[U][G][A][C][C][U][U][A] = 2.000;
+ int22_ar[U][G][A][C][G][A][U][A] = 2.000;
+ int22_ar[U][G][A][C][G][C][U][A] = 2.000;
+ int22_ar[U][G][A][C][G][G][U][A] = 2.000;
+ int22_ar[U][G][A][C][G][U][U][A] = 2.000;
+ int22_ar[U][G][A][C][U][A][U][A] = 3.400;
+ int22_ar[U][G][A][C][U][C][U][A] = 2.800;
+ int22_ar[U][G][A][C][U][G][U][A] = 2.700;
+ int22_ar[U][G][A][C][U][U][U][A] = 2.000;
+ int22_ar[U][G][A][G][A][A][U][A] = 1.700;
+ int22_ar[U][G][A][G][A][C][U][A] = 1.700;
+ int22_ar[U][G][A][G][A][G][U][A] = 0.700;
+ int22_ar[U][G][A][G][A][U][U][A] = 2.000;
+ int22_ar[U][G][A][G][C][A][U][A] = 2.000;
+ int22_ar[U][G][A][G][C][C][U][A] = 2.000;
+ int22_ar[U][G][A][G][C][G][U][A] = 2.000;
+ int22_ar[U][G][A][G][C][U][U][A] = 2.000;
+ int22_ar[U][G][A][G][G][A][U][A] = 2.100;
+ int22_ar[U][G][A][G][G][C][U][A] = 2.100;
+ int22_ar[U][G][A][G][G][G][U][A] = 1.100;
+ int22_ar[U][G][A][G][G][U][U][A] = 2.000;
+ int22_ar[U][G][A][G][U][A][U][A] = 1.000;
+ int22_ar[U][G][A][G][U][C][U][A] = 0.000;
+ int22_ar[U][G][A][G][U][G][U][A] = 0.700;
+ int22_ar[U][G][A][G][U][U][U][A] = 2.000;
+ int22_ar[U][G][A][U][A][A][U][A] = 2.000;
+ int22_ar[U][G][A][U][A][C][U][A] = 2.000;
+ int22_ar[U][G][A][U][A][G][U][A] = 2.000;
+ int22_ar[U][G][A][U][A][U][U][A] = 2.000;
+ int22_ar[U][G][A][U][C][A][U][A] = 3.100;
+ int22_ar[U][G][A][U][C][C][U][A] = 2.500;
+ int22_ar[U][G][A][U][C][G][U][A] = 2.400;
+ int22_ar[U][G][A][U][C][U][U][A] = 2.000;
+ int22_ar[U][G][A][U][G][A][U][A] = 2.200;
+ int22_ar[U][G][A][U][G][C][U][A] = 1.200;
+ int22_ar[U][G][A][U][G][G][U][A] = 2.000;
+ int22_ar[U][G][A][U][G][U][U][A] = 2.000;
+ int22_ar[U][G][A][U][U][A][U][A] = 2.900;
+ int22_ar[U][G][A][U][U][C][U][A] = 1.900;
+ int22_ar[U][G][A][U][U][G][U][A] = 2.700;
+ int22_ar[U][G][A][U][U][U][U][A] = 2.000;
+ int22_ar[U][G][C][A][A][A][U][A] = 2.300;
+ int22_ar[U][G][C][A][A][C][U][A] = 3.400;
+ int22_ar[U][G][C][A][A][G][U][A] = 2.000;
+ int22_ar[U][G][C][A][A][U][U][A] = 3.100;
+ int22_ar[U][G][C][A][C][A][U][A] = 1.900;
+ int22_ar[U][G][C][A][C][C][U][A] = 2.300;
+ int22_ar[U][G][C][A][C][G][U][A] = 2.000;
+ int22_ar[U][G][C][A][C][U][U][A] = 2.000;
+ int22_ar[U][G][C][A][G][A][U][A] = 1.300;
+ int22_ar[U][G][C][A][G][C][U][A] = 2.700;
+ int22_ar[U][G][C][A][G][G][U][A] = 2.000;
+ int22_ar[U][G][C][A][G][U][U][A] = 2.400;
+ int22_ar[U][G][C][A][U][A][U][A] = 2.000;
+ int22_ar[U][G][C][A][U][C][U][A] = 2.000;
+ int22_ar[U][G][C][A][U][G][U][A] = 2.000;
+ int22_ar[U][G][C][A][U][U][U][A] = 2.000;
+ int22_ar[U][G][C][C][A][A][U][A] = 2.300;
+ int22_ar[U][G][C][C][A][C][U][A] = 2.800;
+ int22_ar[U][G][C][C][A][G][U][A] = 2.000;
+ int22_ar[U][G][C][C][A][U][U][A] = 2.500;
+ int22_ar[U][G][C][C][C][A][U][A] = 2.300;
+ int22_ar[U][G][C][C][C][C][U][A] = 2.800;
+ int22_ar[U][G][C][C][C][G][U][A] = 2.000;
+ int22_ar[U][G][C][C][C][U][U][A] = 2.500;
+ int22_ar[U][G][C][C][G][A][U][A] = 2.000;
+ int22_ar[U][G][C][C][G][C][U][A] = 2.000;
+ int22_ar[U][G][C][C][G][G][U][A] = 2.000;
+ int22_ar[U][G][C][C][G][U][U][A] = 2.000;
+ int22_ar[U][G][C][C][U][A][U][A] = 2.300;
+ int22_ar[U][G][C][C][U][C][U][A] = 2.800;
+ int22_ar[U][G][C][C][U][G][U][A] = 2.000;
+ int22_ar[U][G][C][C][U][U][U][A] = 2.500;
+ int22_ar[U][G][C][G][A][A][U][A] = 1.300;
+ int22_ar[U][G][C][G][A][C][U][A] = 2.700;
+ int22_ar[U][G][C][G][A][G][U][A] = 2.000;
+ int22_ar[U][G][C][G][A][U][U][A] = 2.400;
+ int22_ar[U][G][C][G][C][A][U][A] = 2.000;
+ int22_ar[U][G][C][G][C][C][U][A] = 2.000;
+ int22_ar[U][G][C][G][C][G][U][A] = 2.000;
+ int22_ar[U][G][C][G][C][U][U][A] = 2.000;
+ int22_ar[U][G][C][G][G][A][U][A] = 1.700;
+ int22_ar[U][G][C][G][G][C][U][A] = 2.700;
+ int22_ar[U][G][C][G][G][G][U][A] = 2.000;
+ int22_ar[U][G][C][G][G][U][U][A] = 2.400;
+ int22_ar[U][G][C][G][U][A][U][A] = -0.500;
+ int22_ar[U][G][C][G][U][C][U][A] = 1.000;
+ int22_ar[U][G][C][G][U][G][U][A] = 2.000;
+ int22_ar[U][G][C][G][U][U][U][A] = 0.700;
+ int22_ar[U][G][C][U][A][A][U][A] = 2.000;
+ int22_ar[U][G][C][U][A][C][U][A] = 2.000;
+ int22_ar[U][G][C][U][A][G][U][A] = 2.000;
+ int22_ar[U][G][C][U][A][U][U][A] = 2.000;
+ int22_ar[U][G][C][U][C][A][U][A] = 2.000;
+ int22_ar[U][G][C][U][C][C][U][A] = 2.500;
+ int22_ar[U][G][C][U][C][G][U][A] = 2.000;
+ int22_ar[U][G][C][U][C][U][U][A] = 2.200;
+ int22_ar[U][G][C][U][G][A][U][A] = 0.800;
+ int22_ar[U][G][C][U][G][C][U][A] = 2.200;
+ int22_ar[U][G][C][U][G][G][U][A] = 2.000;
+ int22_ar[U][G][C][U][G][U][U][A] = 1.900;
+ int22_ar[U][G][C][U][U][A][U][A] = 1.500;
+ int22_ar[U][G][C][U][U][C][U][A] = 1.900;
+ int22_ar[U][G][C][U][U][G][U][A] = 2.000;
+ int22_ar[U][G][C][U][U][U][U][A] = 1.600;
+ int22_ar[U][G][G][A][A][A][U][A] = 1.700;
+ int22_ar[U][G][G][A][A][C][U][A] = 2.000;
+ int22_ar[U][G][G][A][A][G][U][A] = 2.100;
+ int22_ar[U][G][G][A][A][U][U][A] = 2.200;
+ int22_ar[U][G][G][A][C][A][U][A] = 1.300;
+ int22_ar[U][G][G][A][C][C][U][A] = 2.000;
+ int22_ar[U][G][G][A][C][G][U][A] = 1.700;
+ int22_ar[U][G][G][A][C][U][U][A] = 0.800;
+ int22_ar[U][G][G][A][G][A][U][A] = 0.700;
+ int22_ar[U][G][G][A][G][C][U][A] = 2.000;
+ int22_ar[U][G][G][A][G][G][U][A] = 1.100;
+ int22_ar[U][G][G][A][G][U][U][A] = 2.000;
+ int22_ar[U][G][G][A][U][A][U][A] = 2.000;
+ int22_ar[U][G][G][A][U][C][U][A] = 2.000;
+ int22_ar[U][G][G][A][U][G][U][A] = 2.000;
+ int22_ar[U][G][G][A][U][U][U][A] = 2.000;
+ int22_ar[U][G][G][C][A][A][U][A] = 1.700;
+ int22_ar[U][G][G][C][A][C][U][A] = 2.000;
+ int22_ar[U][G][G][C][A][G][U][A] = 2.100;
+ int22_ar[U][G][G][C][A][U][U][A] = 1.200;
+ int22_ar[U][G][G][C][C][A][U][A] = 2.700;
+ int22_ar[U][G][G][C][C][C][U][A] = 2.000;
+ int22_ar[U][G][G][C][C][G][U][A] = 2.700;
+ int22_ar[U][G][G][C][C][U][U][A] = 2.200;
+ int22_ar[U][G][G][C][G][A][U][A] = 2.000;
+ int22_ar[U][G][G][C][G][C][U][A] = 2.000;
+ int22_ar[U][G][G][C][G][G][U][A] = 2.000;
+ int22_ar[U][G][G][C][G][U][U][A] = 2.000;
+ int22_ar[U][G][G][C][U][A][U][A] = 2.700;
+ int22_ar[U][G][G][C][U][C][U][A] = 2.000;
+ int22_ar[U][G][G][C][U][G][U][A] = 2.700;
+ int22_ar[U][G][G][C][U][U][U][A] = 2.200;
+ int22_ar[U][G][G][G][A][A][U][A] = 0.700;
+ int22_ar[U][G][G][G][A][C][U][A] = 2.000;
+ int22_ar[U][G][G][G][A][G][U][A] = 1.100;
+ int22_ar[U][G][G][G][A][U][U][A] = 2.000;
+ int22_ar[U][G][G][G][C][A][U][A] = 2.000;
+ int22_ar[U][G][G][G][C][C][U][A] = 2.000;
+ int22_ar[U][G][G][G][C][G][U][A] = 2.000;
+ int22_ar[U][G][G][G][C][U][U][A] = 2.000;
+ int22_ar[U][G][G][G][G][A][U][A] = 1.100;
+ int22_ar[U][G][G][G][G][C][U][A] = 2.000;
+ int22_ar[U][G][G][G][G][G][U][A] = 1.500;
+ int22_ar[U][G][G][G][G][U][U][A] = 1.600;
+ int22_ar[U][G][G][G][U][A][U][A] = 0.700;
+ int22_ar[U][G][G][G][U][C][U][A] = 2.000;
+ int22_ar[U][G][G][G][U][G][U][A] = 0.300;
+ int22_ar[U][G][G][G][U][U][U][A] = -1.600;
+ int22_ar[U][G][G][U][A][A][U][A] = 2.000;
+ int22_ar[U][G][G][U][A][C][U][A] = 2.000;
+ int22_ar[U][G][G][U][A][G][U][A] = 2.000;
+ int22_ar[U][G][G][U][A][U][U][A] = 2.000;
+ int22_ar[U][G][G][U][C][A][U][A] = 2.400;
+ int22_ar[U][G][G][U][C][C][U][A] = 2.000;
+ int22_ar[U][G][G][U][C][G][U][A] = 2.400;
+ int22_ar[U][G][G][U][C][U][U][A] = 1.900;
+ int22_ar[U][G][G][U][G][A][U][A] = 2.000;
+ int22_ar[U][G][G][U][G][C][U][A] = 2.000;
+ int22_ar[U][G][G][U][G][G][U][A] = 1.600;
+ int22_ar[U][G][G][U][G][U][U][A] = -0.300;
+ int22_ar[U][G][G][U][U][A][U][A] = 2.700;
+ int22_ar[U][G][G][U][U][C][U][A] = 2.000;
+ int22_ar[U][G][G][U][U][G][U][A] = 2.300;
+ int22_ar[U][G][G][U][U][U][U][A] = 2.200;
+ int22_ar[U][G][U][A][A][A][U][A] = 2.000;
+ int22_ar[U][G][U][A][A][C][U][A] = 3.400;
+ int22_ar[U][G][U][A][A][G][U][A] = 1.000;
+ int22_ar[U][G][U][A][A][U][U][A] = 2.900;
+ int22_ar[U][G][U][A][C][A][U][A] = 2.000;
+ int22_ar[U][G][U][A][C][C][U][A] = 2.300;
+ int22_ar[U][G][U][A][C][G][U][A] = -0.500;
+ int22_ar[U][G][U][A][C][U][U][A] = 1.500;
+ int22_ar[U][G][U][A][G][A][U][A] = 2.000;
+ int22_ar[U][G][U][A][G][C][U][A] = 2.700;
+ int22_ar[U][G][U][A][G][G][U][A] = 0.700;
+ int22_ar[U][G][U][A][G][U][U][A] = 2.700;
+ int22_ar[U][G][U][A][U][A][U][A] = 2.000;
+ int22_ar[U][G][U][A][U][C][U][A] = 2.000;
+ int22_ar[U][G][U][A][U][G][U][A] = 2.000;
+ int22_ar[U][G][U][A][U][U][U][A] = 2.000;
+ int22_ar[U][G][U][C][A][A][U][A] = 2.000;
+ int22_ar[U][G][U][C][A][C][U][A] = 2.800;
+ int22_ar[U][G][U][C][A][G][U][A] = 0.000;
+ int22_ar[U][G][U][C][A][U][U][A] = 1.900;
+ int22_ar[U][G][U][C][C][A][U][A] = 2.000;
+ int22_ar[U][G][U][C][C][C][U][A] = 2.800;
+ int22_ar[U][G][U][C][C][G][U][A] = 1.000;
+ int22_ar[U][G][U][C][C][U][U][A] = 1.900;
+ int22_ar[U][G][U][C][G][A][U][A] = 2.000;
+ int22_ar[U][G][U][C][G][C][U][A] = 2.000;
+ int22_ar[U][G][U][C][G][G][U][A] = 2.000;
+ int22_ar[U][G][U][C][G][U][U][A] = 2.000;
+ int22_ar[U][G][U][C][U][A][U][A] = 2.000;
+ int22_ar[U][G][U][C][U][C][U][A] = 2.800;
+ int22_ar[U][G][U][C][U][G][U][A] = 1.000;
+ int22_ar[U][G][U][C][U][U][U][A] = 1.900;
+ int22_ar[U][G][U][G][A][A][U][A] = 2.000;
+ int22_ar[U][G][U][G][A][C][U][A] = 2.700;
+ int22_ar[U][G][U][G][A][G][U][A] = 0.700;
+ int22_ar[U][G][U][G][A][U][U][A] = 2.700;
+ int22_ar[U][G][U][G][C][A][U][A] = 2.000;
+ int22_ar[U][G][U][G][C][C][U][A] = 2.000;
+ int22_ar[U][G][U][G][C][G][U][A] = 2.000;
+ int22_ar[U][G][U][G][C][U][U][A] = 2.000;
+ int22_ar[U][G][U][G][G][A][U][A] = 2.000;
+ int22_ar[U][G][U][G][G][C][U][A] = 2.700;
+ int22_ar[U][G][U][G][G][G][U][A] = 0.300;
+ int22_ar[U][G][U][G][G][U][U][A] = 2.300;
+ int22_ar[U][G][U][G][U][A][U][A] = 2.000;
+ int22_ar[U][G][U][G][U][C][U][A] = 1.000;
+ int22_ar[U][G][U][G][U][G][U][A] = -2.900;
+ int22_ar[U][G][U][G][U][U][U][A] = 0.900;
+ int22_ar[U][G][U][U][A][A][U][A] = 2.000;
+ int22_ar[U][G][U][U][A][C][U][A] = 2.000;
+ int22_ar[U][G][U][U][A][G][U][A] = 2.000;
+ int22_ar[U][G][U][U][A][U][U][A] = 2.000;
+ int22_ar[U][G][U][U][C][A][U][A] = 2.000;
+ int22_ar[U][G][U][U][C][C][U][A] = 2.500;
+ int22_ar[U][G][U][U][C][G][U][A] = 0.700;
+ int22_ar[U][G][U][U][C][U][U][A] = 1.600;
+ int22_ar[U][G][U][U][G][A][U][A] = 2.000;
+ int22_ar[U][G][U][U][G][C][U][A] = 2.200;
+ int22_ar[U][G][U][U][G][G][U][A] = -1.600;
+ int22_ar[U][G][U][U][G][U][U][A] = 2.200;
+ int22_ar[U][G][U][U][U][A][U][A] = 2.000;
+ int22_ar[U][G][U][U][U][C][U][A] = 1.900;
+ int22_ar[U][G][U][U][U][G][U][A] = 0.900;
+ int22_ar[U][G][U][U][U][U][U][A] = 1.100;
+ int22_ar[U][G][A][A][A][A][U][G] = 2.800;
+ int22_ar[U][G][A][A][A][C][U][G] = 2.800;
+ int22_ar[U][G][A][A][A][G][U][G] = 1.700;
+ int22_ar[U][G][A][A][A][U][U][G] = 2.000;
+ int22_ar[U][G][A][A][C][A][U][G] = 2.300;
+ int22_ar[U][G][A][A][C][C][U][G] = 2.300;
+ int22_ar[U][G][A][A][C][G][U][G] = 1.300;
+ int22_ar[U][G][A][A][C][U][U][G] = 2.000;
+ int22_ar[U][G][A][A][G][A][U][G] = 1.700;
+ int22_ar[U][G][A][A][G][C][U][G] = 1.700;
+ int22_ar[U][G][A][A][G][G][U][G] = 0.700;
+ int22_ar[U][G][A][A][G][U][U][G] = 2.000;
+ int22_ar[U][G][A][A][U][A][U][G] = 2.000;
+ int22_ar[U][G][A][A][U][C][U][G] = 2.000;
+ int22_ar[U][G][A][A][U][G][U][G] = 2.000;
+ int22_ar[U][G][A][A][U][U][U][G] = 2.000;
+ int22_ar[U][G][A][C][A][A][U][G] = 2.800;
+ int22_ar[U][G][A][C][A][C][U][G] = 2.800;
+ int22_ar[U][G][A][C][A][G][U][G] = 1.700;
+ int22_ar[U][G][A][C][A][U][U][G] = 2.000;
+ int22_ar[U][G][A][C][C][A][U][G] = 3.400;
+ int22_ar[U][G][A][C][C][C][U][G] = 2.800;
+ int22_ar[U][G][A][C][C][G][U][G] = 2.700;
+ int22_ar[U][G][A][C][C][U][U][G] = 2.000;
+ int22_ar[U][G][A][C][G][A][U][G] = 2.000;
+ int22_ar[U][G][A][C][G][C][U][G] = 2.000;
+ int22_ar[U][G][A][C][G][G][U][G] = 2.000;
+ int22_ar[U][G][A][C][G][U][U][G] = 2.000;
+ int22_ar[U][G][A][C][U][A][U][G] = 3.400;
+ int22_ar[U][G][A][C][U][C][U][G] = 2.800;
+ int22_ar[U][G][A][C][U][G][U][G] = 2.700;
+ int22_ar[U][G][A][C][U][U][U][G] = 2.000;
+ int22_ar[U][G][A][G][A][A][U][G] = 1.700;
+ int22_ar[U][G][A][G][A][C][U][G] = 1.700;
+ int22_ar[U][G][A][G][A][G][U][G] = 0.700;
+ int22_ar[U][G][A][G][A][U][U][G] = 2.000;
+ int22_ar[U][G][A][G][C][A][U][G] = 2.000;
+ int22_ar[U][G][A][G][C][C][U][G] = 2.000;
+ int22_ar[U][G][A][G][C][G][U][G] = 2.000;
+ int22_ar[U][G][A][G][C][U][U][G] = 2.000;
+ int22_ar[U][G][A][G][G][A][U][G] = 2.100;
+ int22_ar[U][G][A][G][G][C][U][G] = 2.100;
+ int22_ar[U][G][A][G][G][G][U][G] = 1.100;
+ int22_ar[U][G][A][G][G][U][U][G] = 2.000;
+ int22_ar[U][G][A][G][U][A][U][G] = 1.000;
+ int22_ar[U][G][A][G][U][C][U][G] = 0.000;
+ int22_ar[U][G][A][G][U][G][U][G] = 0.700;
+ int22_ar[U][G][A][G][U][U][U][G] = 2.000;
+ int22_ar[U][G][A][U][A][A][U][G] = 2.000;
+ int22_ar[U][G][A][U][A][C][U][G] = 2.000;
+ int22_ar[U][G][A][U][A][G][U][G] = 2.000;
+ int22_ar[U][G][A][U][A][U][U][G] = 2.000;
+ int22_ar[U][G][A][U][C][A][U][G] = 3.100;
+ int22_ar[U][G][A][U][C][C][U][G] = 2.500;
+ int22_ar[U][G][A][U][C][G][U][G] = 2.400;
+ int22_ar[U][G][A][U][C][U][U][G] = 2.000;
+ int22_ar[U][G][A][U][G][A][U][G] = 2.200;
+ int22_ar[U][G][A][U][G][C][U][G] = 1.200;
+ int22_ar[U][G][A][U][G][G][U][G] = 2.000;
+ int22_ar[U][G][A][U][G][U][U][G] = 2.000;
+ int22_ar[U][G][A][U][U][A][U][G] = 2.900;
+ int22_ar[U][G][A][U][U][C][U][G] = 1.900;
+ int22_ar[U][G][A][U][U][G][U][G] = 2.700;
+ int22_ar[U][G][A][U][U][U][U][G] = 2.000;
+ int22_ar[U][G][C][A][A][A][U][G] = 2.300;
+ int22_ar[U][G][C][A][A][C][U][G] = 3.400;
+ int22_ar[U][G][C][A][A][G][U][G] = 2.000;
+ int22_ar[U][G][C][A][A][U][U][G] = 3.100;
+ int22_ar[U][G][C][A][C][A][U][G] = 1.900;
+ int22_ar[U][G][C][A][C][C][U][G] = 2.300;
+ int22_ar[U][G][C][A][C][G][U][G] = 2.000;
+ int22_ar[U][G][C][A][C][U][U][G] = 2.000;
+ int22_ar[U][G][C][A][G][A][U][G] = 1.300;
+ int22_ar[U][G][C][A][G][C][U][G] = 2.700;
+ int22_ar[U][G][C][A][G][G][U][G] = 2.000;
+ int22_ar[U][G][C][A][G][U][U][G] = 2.400;
+ int22_ar[U][G][C][A][U][A][U][G] = 2.000;
+ int22_ar[U][G][C][A][U][C][U][G] = 2.000;
+ int22_ar[U][G][C][A][U][G][U][G] = 2.000;
+ int22_ar[U][G][C][A][U][U][U][G] = 2.000;
+ int22_ar[U][G][C][C][A][A][U][G] = 2.300;
+ int22_ar[U][G][C][C][A][C][U][G] = 2.800;
+ int22_ar[U][G][C][C][A][G][U][G] = 2.000;
+ int22_ar[U][G][C][C][A][U][U][G] = 2.500;
+ int22_ar[U][G][C][C][C][A][U][G] = 2.300;
+ int22_ar[U][G][C][C][C][C][U][G] = 2.800;
+ int22_ar[U][G][C][C][C][G][U][G] = 2.000;
+ int22_ar[U][G][C][C][C][U][U][G] = 2.500;
+ int22_ar[U][G][C][C][G][A][U][G] = 2.000;
+ int22_ar[U][G][C][C][G][C][U][G] = 2.000;
+ int22_ar[U][G][C][C][G][G][U][G] = 2.000;
+ int22_ar[U][G][C][C][G][U][U][G] = 2.000;
+ int22_ar[U][G][C][C][U][A][U][G] = 2.300;
+ int22_ar[U][G][C][C][U][C][U][G] = 2.800;
+ int22_ar[U][G][C][C][U][G][U][G] = 2.000;
+ int22_ar[U][G][C][C][U][U][U][G] = 2.500;
+ int22_ar[U][G][C][G][A][A][U][G] = 1.300;
+ int22_ar[U][G][C][G][A][C][U][G] = 2.700;
+ int22_ar[U][G][C][G][A][G][U][G] = 2.000;
+ int22_ar[U][G][C][G][A][U][U][G] = 2.400;
+ int22_ar[U][G][C][G][C][A][U][G] = 2.000;
+ int22_ar[U][G][C][G][C][C][U][G] = 2.000;
+ int22_ar[U][G][C][G][C][G][U][G] = 2.000;
+ int22_ar[U][G][C][G][C][U][U][G] = 2.000;
+ int22_ar[U][G][C][G][G][A][U][G] = 1.700;
+ int22_ar[U][G][C][G][G][C][U][G] = 2.700;
+ int22_ar[U][G][C][G][G][G][U][G] = 2.000;
+ int22_ar[U][G][C][G][G][U][U][G] = 2.400;
+ int22_ar[U][G][C][G][U][A][U][G] = -0.500;
+ int22_ar[U][G][C][G][U][C][U][G] = 1.000;
+ int22_ar[U][G][C][G][U][G][U][G] = 2.000;
+ int22_ar[U][G][C][G][U][U][U][G] = 0.700;
+ int22_ar[U][G][C][U][A][A][U][G] = 2.000;
+ int22_ar[U][G][C][U][A][C][U][G] = 2.000;
+ int22_ar[U][G][C][U][A][G][U][G] = 2.000;
+ int22_ar[U][G][C][U][A][U][U][G] = 2.000;
+ int22_ar[U][G][C][U][C][A][U][G] = 2.000;
+ int22_ar[U][G][C][U][C][C][U][G] = 2.500;
+ int22_ar[U][G][C][U][C][G][U][G] = 2.000;
+ int22_ar[U][G][C][U][C][U][U][G] = 2.200;
+ int22_ar[U][G][C][U][G][A][U][G] = 0.800;
+ int22_ar[U][G][C][U][G][C][U][G] = 2.200;
+ int22_ar[U][G][C][U][G][G][U][G] = 2.000;
+ int22_ar[U][G][C][U][G][U][U][G] = 1.900;
+ int22_ar[U][G][C][U][U][A][U][G] = 1.500;
+ int22_ar[U][G][C][U][U][C][U][G] = 1.900;
+ int22_ar[U][G][C][U][U][G][U][G] = 2.000;
+ int22_ar[U][G][C][U][U][U][U][G] = 1.600;
+ int22_ar[U][G][G][A][A][A][U][G] = 1.700;
+ int22_ar[U][G][G][A][A][C][U][G] = 2.000;
+ int22_ar[U][G][G][A][A][G][U][G] = 2.100;
+ int22_ar[U][G][G][A][A][U][U][G] = 2.200;
+ int22_ar[U][G][G][A][C][A][U][G] = 1.300;
+ int22_ar[U][G][G][A][C][C][U][G] = 2.000;
+ int22_ar[U][G][G][A][C][G][U][G] = 1.700;
+ int22_ar[U][G][G][A][C][U][U][G] = 0.800;
+ int22_ar[U][G][G][A][G][A][U][G] = 0.700;
+ int22_ar[U][G][G][A][G][C][U][G] = 2.000;
+ int22_ar[U][G][G][A][G][G][U][G] = 1.100;
+ int22_ar[U][G][G][A][G][U][U][G] = 2.000;
+ int22_ar[U][G][G][A][U][A][U][G] = 2.000;
+ int22_ar[U][G][G][A][U][C][U][G] = 2.000;
+ int22_ar[U][G][G][A][U][G][U][G] = 2.000;
+ int22_ar[U][G][G][A][U][U][U][G] = 2.000;
+ int22_ar[U][G][G][C][A][A][U][G] = 1.700;
+ int22_ar[U][G][G][C][A][C][U][G] = 2.000;
+ int22_ar[U][G][G][C][A][G][U][G] = 2.100;
+ int22_ar[U][G][G][C][A][U][U][G] = 1.200;
+ int22_ar[U][G][G][C][C][A][U][G] = 2.700;
+ int22_ar[U][G][G][C][C][C][U][G] = 2.000;
+ int22_ar[U][G][G][C][C][G][U][G] = 2.700;
+ int22_ar[U][G][G][C][C][U][U][G] = 2.200;
+ int22_ar[U][G][G][C][G][A][U][G] = 2.000;
+ int22_ar[U][G][G][C][G][C][U][G] = 2.000;
+ int22_ar[U][G][G][C][G][G][U][G] = 2.000;
+ int22_ar[U][G][G][C][G][U][U][G] = 2.000;
+ int22_ar[U][G][G][C][U][A][U][G] = 2.700;
+ int22_ar[U][G][G][C][U][C][U][G] = 2.000;
+ int22_ar[U][G][G][C][U][G][U][G] = 2.700;
+ int22_ar[U][G][G][C][U][U][U][G] = 2.200;
+ int22_ar[U][G][G][G][A][A][U][G] = 0.700;
+ int22_ar[U][G][G][G][A][C][U][G] = 2.000;
+ int22_ar[U][G][G][G][A][G][U][G] = 1.100;
+ int22_ar[U][G][G][G][A][U][U][G] = 2.000;
+ int22_ar[U][G][G][G][C][A][U][G] = 2.000;
+ int22_ar[U][G][G][G][C][C][U][G] = 2.000;
+ int22_ar[U][G][G][G][C][G][U][G] = 2.000;
+ int22_ar[U][G][G][G][C][U][U][G] = 2.000;
+ int22_ar[U][G][G][G][G][A][U][G] = 1.100;
+ int22_ar[U][G][G][G][G][C][U][G] = 2.000;
+ int22_ar[U][G][G][G][G][G][U][G] = 1.500;
+ int22_ar[U][G][G][G][G][U][U][G] = 1.600;
+ int22_ar[U][G][G][G][U][A][U][G] = 0.700;
+ int22_ar[U][G][G][G][U][C][U][G] = 2.000;
+ int22_ar[U][G][G][G][U][G][U][G] = 0.300;
+ int22_ar[U][G][G][G][U][U][U][G] = -1.600;
+ int22_ar[U][G][G][U][A][A][U][G] = 2.000;
+ int22_ar[U][G][G][U][A][C][U][G] = 2.000;
+ int22_ar[U][G][G][U][A][G][U][G] = 2.000;
+ int22_ar[U][G][G][U][A][U][U][G] = 2.000;
+ int22_ar[U][G][G][U][C][A][U][G] = 2.400;
+ int22_ar[U][G][G][U][C][C][U][G] = 2.000;
+ int22_ar[U][G][G][U][C][G][U][G] = 2.400;
+ int22_ar[U][G][G][U][C][U][U][G] = 1.900;
+ int22_ar[U][G][G][U][G][A][U][G] = 2.000;
+ int22_ar[U][G][G][U][G][C][U][G] = 2.000;
+ int22_ar[U][G][G][U][G][G][U][G] = 1.600;
+ int22_ar[U][G][G][U][G][U][U][G] = -0.300;
+ int22_ar[U][G][G][U][U][A][U][G] = 2.700;
+ int22_ar[U][G][G][U][U][C][U][G] = 2.000;
+ int22_ar[U][G][G][U][U][G][U][G] = 2.300;
+ int22_ar[U][G][G][U][U][U][U][G] = 2.200;
+ int22_ar[U][G][U][A][A][A][U][G] = 2.000;
+ int22_ar[U][G][U][A][A][C][U][G] = 3.400;
+ int22_ar[U][G][U][A][A][G][U][G] = 1.000;
+ int22_ar[U][G][U][A][A][U][U][G] = 2.900;
+ int22_ar[U][G][U][A][C][A][U][G] = 2.000;
+ int22_ar[U][G][U][A][C][C][U][G] = 2.300;
+ int22_ar[U][G][U][A][C][G][U][G] = -0.500;
+ int22_ar[U][G][U][A][C][U][U][G] = 1.500;
+ int22_ar[U][G][U][A][G][A][U][G] = 2.000;
+ int22_ar[U][G][U][A][G][C][U][G] = 2.700;
+ int22_ar[U][G][U][A][G][G][U][G] = 0.700;
+ int22_ar[U][G][U][A][G][U][U][G] = 2.700;
+ int22_ar[U][G][U][A][U][A][U][G] = 2.000;
+ int22_ar[U][G][U][A][U][C][U][G] = 2.000;
+ int22_ar[U][G][U][A][U][G][U][G] = 2.000;
+ int22_ar[U][G][U][A][U][U][U][G] = 2.000;
+ int22_ar[U][G][U][C][A][A][U][G] = 2.000;
+ int22_ar[U][G][U][C][A][C][U][G] = 2.800;
+ int22_ar[U][G][U][C][A][G][U][G] = 0.000;
+ int22_ar[U][G][U][C][A][U][U][G] = 1.900;
+ int22_ar[U][G][U][C][C][A][U][G] = 2.000;
+ int22_ar[U][G][U][C][C][C][U][G] = 2.800;
+ int22_ar[U][G][U][C][C][G][U][G] = 1.000;
+ int22_ar[U][G][U][C][C][U][U][G] = 1.900;
+ int22_ar[U][G][U][C][G][A][U][G] = 2.000;
+ int22_ar[U][G][U][C][G][C][U][G] = 2.000;
+ int22_ar[U][G][U][C][G][G][U][G] = 2.000;
+ int22_ar[U][G][U][C][G][U][U][G] = 2.000;
+ int22_ar[U][G][U][C][U][A][U][G] = 2.000;
+ int22_ar[U][G][U][C][U][C][U][G] = 2.800;
+ int22_ar[U][G][U][C][U][G][U][G] = 1.000;
+ int22_ar[U][G][U][C][U][U][U][G] = 1.900;
+ int22_ar[U][G][U][G][A][A][U][G] = 2.000;
+ int22_ar[U][G][U][G][A][C][U][G] = 2.700;
+ int22_ar[U][G][U][G][A][G][U][G] = 0.700;
+ int22_ar[U][G][U][G][A][U][U][G] = 2.700;
+ int22_ar[U][G][U][G][C][A][U][G] = 2.000;
+ int22_ar[U][G][U][G][C][C][U][G] = 2.000;
+ int22_ar[U][G][U][G][C][G][U][G] = 2.000;
+ int22_ar[U][G][U][G][C][U][U][G] = 2.000;
+ int22_ar[U][G][U][G][G][A][U][G] = 2.000;
+ int22_ar[U][G][U][G][G][C][U][G] = 2.700;
+ int22_ar[U][G][U][G][G][G][U][G] = 0.300;
+ int22_ar[U][G][U][G][G][U][U][G] = 2.300;
+ int22_ar[U][G][U][G][U][A][U][G] = 2.000;
+ int22_ar[U][G][U][G][U][C][U][G] = 1.000;
+ int22_ar[U][G][U][G][U][G][U][G] = -2.900;
+ int22_ar[U][G][U][G][U][U][U][G] = 0.900;
+ int22_ar[U][G][U][U][A][A][U][G] = 2.000;
+ int22_ar[U][G][U][U][A][C][U][G] = 2.000;
+ int22_ar[U][G][U][U][A][G][U][G] = 2.000;
+ int22_ar[U][G][U][U][A][U][U][G] = 2.000;
+ int22_ar[U][G][U][U][C][A][U][G] = 2.000;
+ int22_ar[U][G][U][U][C][C][U][G] = 2.500;
+ int22_ar[U][G][U][U][C][G][U][G] = 0.700;
+ int22_ar[U][G][U][U][C][U][U][G] = 1.600;
+ int22_ar[U][G][U][U][G][A][U][G] = 2.000;
+ int22_ar[U][G][U][U][G][C][U][G] = 2.200;
+ int22_ar[U][G][U][U][G][G][U][G] = -1.600;
+ int22_ar[U][G][U][U][G][U][U][G] = 2.200;
+ int22_ar[U][G][U][U][U][A][U][G] = 2.000;
+ int22_ar[U][G][U][U][U][C][U][G] = 1.900;
+ int22_ar[U][G][U][U][U][G][U][G] = 0.900;
+ int22_ar[U][G][U][U][U][U][U][G] = 1.100;
+}
+
+
+
+void init_canPair(){
+ int i,j;
+ for (i=0;i<ALPHASIZE+1;i++) /* +1 because of masking letter X */
+ for(j=0;j<ALPHASIZE+1;j++)
+ canPair[i][j]=0;
+
+ canPair [A][U] = 1;
+ canPair [U][A] = 1;
+ canPair [C][G] = 1;
+ canPair [G][C] = 1;
+ canPair [G][U] = 1;
+ canPair [U][G] = 1;
+}
+
+
+void init_energies()
+{
+ init_il_asym_ar();
+
+ init_stack_dg_ar();
+ init_tstackh_dg_ar();
+ init_tstacki_dg_ar();
+ init_hl_tetra_ar();
+
+ init_hl_ent_ar();
+ init_bl_ent_ar();
+ init_il_ent_ar();
+
+ init_dr_dangle_dg_ar();
+ init_dl_dangle_dg_ar();
+
+ init_int11_ar();
+ init_int21_ar();
+ init_int22_ar();
+
+ init_canPair();
+}
+
+
+
+
Added: trunk/packages/rnahybrid/branches/upstream/current/src/energy.h
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/src/energy.h (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/src/energy.h 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,133 @@
+/* Copyright (C) 2004 Marc Rehmsmeier, Peter Steffen, Matthias Hoechsmann */
+
+/* This program is free software; you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation; either version 2 of the License, or (at your option) any later version. */
+
+/* This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details. */
+
+/* You should have received a copy of the GNU General Public License along with this program; if not, write to the Free Software Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA */
+
+#ifndef energy_h
+#define energy_h
+
+#include <stdio.h>
+#include <stdlib.h>
+#include <math.h>
+#include "minmax.h"
+#include "input.h"
+
+double e;
+double t;
+double temp;
+double r;
+
+double mloop_close;
+double free_base_penalty;
+double helix_penalty;
+
+double wkn;
+
+double npp;
+double pbp;
+
+double il_asym_ar[16][16];
+
+double stack_dg_ar [ALPHASIZE][ALPHASIZE][ALPHASIZE][ALPHASIZE];
+double tstackh_dg_ar[ALPHASIZE][ALPHASIZE][ALPHASIZE][ALPHASIZE];
+double tstacki_dg_ar[ALPHASIZE][ALPHASIZE][ALPHASIZE][ALPHASIZE];
+double hl_tetra_ar[ALPHASIZE][ALPHASIZE][ALPHASIZE][ALPHASIZE][ALPHASIZE][ALPHASIZE];
+
+double hl_ent_ar[31];
+double bl_ent_ar[31];
+double il_ent_ar[31];
+
+double dr_dangle_dg_ar[ALPHASIZE][ALPHASIZE][ALPHASIZE+1];
+double dl_dangle_dg_ar[ALPHASIZE+1][ALPHASIZE][ALPHASIZE];
+
+double int11_ar[ALPHASIZE][ALPHASIZE][ALPHASIZE][ALPHASIZE][ALPHASIZE][ALPHASIZE];
+double int21_ar[ALPHASIZE][ALPHASIZE][ALPHASIZE][ALPHASIZE][ALPHASIZE][ALPHASIZE][ALPHASIZE];
+double int22_ar[ALPHASIZE][ALPHASIZE][ALPHASIZE][ALPHASIZE][ALPHASIZE][ALPHASIZE][ALPHASIZE][ALPHASIZE];
+
+char canPair[ALPHASIZE][ALPHASIZE];
+
+void init_constants();
+
+#define compl(I,J) canPair[I][J]
+
+double sr_energy(int i, int j);
+
+double dr_energy(int i, int j);
+
+double dli_energy(int i, int j);
+
+double dl_energy(int i, int j);
+
+double dri_energy(int i, int j);
+
+double dangles (int i, int j, int i2, int j2, int k, int l, int k2,int l2);
+
+double sspenalty(int a);
+
+double log_interp(int size);
+
+double hl_ent(int size);
+
+double bl_ent(int size);
+
+#define il_ent(size) ((size)<=30 ? il_ent_ar[(size)] : il_ent_ar[30] + log_interp((size)))
+
+int lengthOf(int i, int j);
+
+#define il_asym(u,v) (il_asym_ar[u][v])
+
+/* double il_asym (int sl, int sr); */
+
+double top_stack(int lb, int rb);
+
+double bot_stack(int lb, int rb);
+
+double bl_stacking (int t, int b, int i, int j);
+
+#define il_stack_open(i,j) tstacki_dg_ar[inpx(i)][inpx((i)+1)][inpy((j)+1)][inpy(j)]
+
+#define il_stack_close(i,j) tstacki_dg_ar[inpy(j)][inpy((j)-1)][inpx((i)-1)][inpx(i)]
+
+double int_special(int i, int j, int t, int b);
+
+double do_il_special(int i, int j, int k, int l, int u, int v, double e);
+
+/* double do_il(int i, int j, int k, int l, int u, int v, double e); */
+
+#define do_il(i,j,k,l,u,v,e) ((e)+il_stack_close((l)+1,(v)+1)+il_ent((l)-(k)+(v)-(u))+il_asym((l)-(k),(v)-(u)))
+
+void init_il_asym_ar();
+
+void init_stack_dg_ar();
+
+void init_tstackh_dg_ar();
+
+void init_hl_tetra_ar();
+
+void init_bl_ent_ar();
+
+void init_il_ent_ar();
+
+void init_tstacki_dg_ar();
+
+void init_dr_dangle_dg_ar();
+
+void init_dl_dangle_dg_ar();
+
+void init_int11_ar();
+
+void init_int21_ar();
+
+void init_int22_ar();
+
+void init_canPair();
+
+void init_energies();
+
+
+
+
+#endif
Added: trunk/packages/rnahybrid/branches/upstream/current/src/fasta.c
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/src/fasta.c (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/src/fasta.c 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,80 @@
+/* Copyright (C) 2004 Marc Rehmsmeier, Peter Steffen, Matthias Hoechsmann */
+
+/* This program is free software; you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation; either version 2 of the License, or (at your option) any later version. */
+
+/* This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details. */
+
+/* You should have received a copy of the GNU General Public License along with this program; if not, write to the Free Software Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA */
+
+#include "fasta.h"
+
+
+void nextAC(FILE *f, char *ac)
+{
+ fpos_t startloc;
+ char s [MAXLINE];
+
+ fgetpos(f,&startloc);
+ while (fgets(s,MAXLINE,f)!=NULL && s[0]!='>');
+ if (s==NULL) {
+ fsetpos(f,&startloc);
+ printf("Error in nextAC. Aborting\n");
+ exit(2);
+ }
+ sscanf(s,">%s",ac);
+}
+
+
+void nextSQ(FILE *f, char *sq, int maxseqlength)
+{
+ fpos_t startloc;
+ char s [MAXLINE];
+
+ int offset = 0;
+ fgetpos(f,&startloc);
+ if (fgets(sq,MAXLINE,f)!=NULL) {
+ while (sq[offset]!='\0')
+ offset++;
+ offset--; // remove newline
+ if (offset > maxseqlength) {
+ return;
+ }
+ fgetpos(f,&startloc);
+ while (fgets(sq+offset,MAXLINE,f)!=NULL)
+ if (sq[offset]=='>') {
+ sq[offset]='\0';
+ fsetpos(f,&startloc);
+ break;
+ }
+ else {
+ while (sq[offset]!='\0')
+ offset++;
+ offset--; // remove newline
+ if (offset > maxseqlength) {
+ return;
+ }
+ fgetpos(f,&startloc);
+ }
+ sq[offset]='\0';
+ return;
+ }
+ fsetpos(f,&startloc);
+ printf("Error in nextSQ. Aborting\n");
+ exit(2);
+}
+
+
+int end(FILE *f)
+{
+ fpos_t startloc;
+ char s [MAXLINE];
+
+ fgetpos(f,&startloc);
+ if (fgets(s,MAXLINE,f)==NULL)
+ return 1;
+ else {
+ fsetpos(f,&startloc);
+ return 0;
+ }
+}
+
Added: trunk/packages/rnahybrid/branches/upstream/current/src/fasta.h
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/src/fasta.h (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/src/fasta.h 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,23 @@
+/* Copyright (C) 2004 Marc Rehmsmeier, Peter Steffen, Matthias Hoechsmann */
+
+/* This program is free software; you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation; either version 2 of the License, or (at your option) any later version. */
+
+/* This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details. */
+
+/* You should have received a copy of the GNU General Public License along with this program; if not, write to the Free Software Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA */
+
+#ifndef fasta_h
+#define fasta_h
+
+#include "globals.h"
+#include <stdio.h>
+
+
+void nextAC(FILE *f, char *ac);
+
+void nextSQ(FILE *f, char *sq, int maxseqlength);
+
+int end(FILE *f);
+
+
+#endif
Added: trunk/packages/rnahybrid/branches/upstream/current/src/globals.h
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/src/globals.h (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/src/globals.h 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,57 @@
+/* Copyright (C) 2004 Marc Rehmsmeier, Peter Steffen, Matthias Hoechsmann */
+
+/* This program is free software; you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation; either version 2 of the License, or (at your option) any later version. */
+
+/* This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details. */
+
+/* You should have received a copy of the GNU General Public License along with this program; if not, write to the Free Software Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA */
+
+#ifndef globals_h
+#define globals_h
+
+
+#define MAXTARGET 2000
+#define MAXQUERY 30
+#define MAXLINE 1000
+#define MAXSEQUENCE 100000
+
+#define ILOOPUPPERLIMITDEFAULT 15
+#define BLOOPUPPERLIMITDEFAULT 15
+
+#define MEAN 500
+#define STDDEV 300
+#define SAMPLESIZE 5000
+
+#define MIRNA_LENGTH_MEAN 22
+#define MIRNA_LENGTH_STDDEV 0
+
+#define MAXTARGETNUMBER 100000
+#define MAXQUERYNUMBER 100000
+
+#define MAXORTHOLOGNUMBER 10
+
+#define BINNUMBER 500
+#define FITLOWERCUTOFFABSOLUTE 2.0
+#define FITUPPERCUTOFFPERCENT 1.0
+
+#define SETNAME_3UTR_FLY "3utr_fly"
+#define SETNAME_3UTR_WORM "3utr_worm"
+#define SETNAME_3UTR_HUMAN "3utr_human"
+
+#define XI_SLOPE_3UTR_FLY (-0.03144)
+#define XI_INTERCEPT_3UTR_FLY (0.7201)
+#define THETA_SLOPE_3UTR_FLY (-0.003429)
+#define THETA_INTERCEPT_3UTR_FLY (0.01634)
+
+#define XI_SLOPE_3UTR_WORM (-0.01074)
+#define XI_INTERCEPT_3UTR_WORM (1.769)
+#define THETA_SLOPE_3UTR_WORM (-0.001154)
+#define THETA_INTERCEPT_3UTR_WORM (0.1419)
+
+#define XI_SLOPE_3UTR_HUMAN (-0.01237)
+#define XI_INTERCEPT_3UTR_HUMAN (1.901)
+#define THETA_SLOPE_3UTR_HUMAN (-0.001678)
+#define THETA_INTERCEPT_3UTR_HUMAN (0.1349)
+
+
+#endif
Added: trunk/packages/rnahybrid/branches/upstream/current/src/hybrid_core.c
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/src/hybrid_core.c (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/src/hybrid_core.c 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,1894 @@
+/* Copyright (C) 2004 Marc Rehmsmeier, Peter Steffen, Matthias Hoechsmann */
+
+/* This program is free software; you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation; either version 2 of the License, or (at your option) any later version. */
+
+/* This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details. */
+
+/* You should have received a copy of the GNU General Public License along with this program; if not, write to the Free Software Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA */
+
+/* compiled by the ADP compiler, version 0.8.342 */
+/* source file: rnahybrid/HybridMFE3_simple_3tab.lhs */
+/* command: */
+/* adpcompile -c rnahybrid/HybridMFE3_simple_3tab.lhs -al mfe enum -bt -bts -o rnahybrid/hybridBack4.c */
+/* -------------------------------------------------------------------------------- */
+
+#include "config.h"
+#include "hybrid_core.h"
+#include "plot.h"
+#include "minmax.h"
+#include "fasta.h"
+#include "input.h"
+#include "energy.h"
+#include "globals.h"
+#include <stdio.h>
+#include <string.h>
+
+
+static char const rcsid[] = "$Id: hybrid_core.c,v 1.6 2004/11/15 20:41:36 marc Exp $";
+
+
+extern int iloop_upper_limit;
+extern int bloop_upper_limit;
+
+/* data structures */
+/* -------------------------------------------------------------------------------- */
+
+struct str1 {
+ double alg_mfe;
+ struct str_Hybrid *alg_enum;
+};
+
+/* signature */
+/* -------------------------------------------------------------------------------- */
+
+#define SIGID__NTID 1
+#define SIGID_Ult 2
+#define SIGID_Ulb 3
+#define SIGID_Eds 4
+#define SIGID_Edt 5
+#define SIGID_Edb 6
+#define SIGID_Sr 7
+#define SIGID_Bt 8
+#define SIGID_Bb 9
+#define SIGID_Il 10
+#define SIGID_El 11
+#define SIGID_Nil 12
+
+
+struct str_Hybrid {
+ int utype;
+ void *entry;
+};
+
+struct str_Hybrid *new_Hybrid(int u, void *entry)
+{
+ struct str_Hybrid *t;
+
+ t=(struct str_Hybrid *) calloc(1, sizeof(struct str_Hybrid ));
+ t->utype = u;
+ t->entry = entry;
+ return(t);
+}
+
+/* signature operators */
+/* -------------------------------------------------------------------------------- */
+
+/* operator _NTID */
+/* -------------------------------------------------------------------------------- */
+
+struct str__NTID {
+ struct str1 a1;
+ struct str1 (*f1)(int , int , int , int );
+ int i11, j11, i21, j21;
+};
+
+struct str_Hybrid *new__NTID(struct str1 (*f1)(int , int , int , int ), int i11, int j11, int i21, int j21)
+{
+ struct str__NTID *t;
+
+ t=(struct str__NTID *) calloc(1, sizeof(struct str__NTID ));
+ t->f1 = f1;
+ t->i11 = i11;
+ t->j11 = j11;
+ t->i21 = i21;
+ t->j21 = j21;
+ return(new_Hybrid(SIGID__NTID, t));
+}
+
+
+/* operator Ult */
+/* -------------------------------------------------------------------------------- */
+
+struct str_Ult {
+ int a1;
+ int a2;
+ struct str1 a3;
+ struct str1 (*f3)(int , int , int , int );
+ int i13, j13, i23, j23;
+};
+
+struct str_Hybrid *new_Ult(int a1, int a2, struct str1 (*f3)(int , int , int , int ), int i13, int j13, int i23, int j23)
+{
+ struct str_Ult *t;
+
+ t=(struct str_Ult *) calloc(1, sizeof(struct str_Ult ));
+ t->a1 = a1;
+ t->a2 = a2;
+ t->f3 = f3;
+ t->i13 = i13;
+ t->j13 = j13;
+ t->i23 = i23;
+ t->j23 = j23;
+ return(new_Hybrid(SIGID_Ult, t));
+}
+
+
+/* operator Ulb */
+/* -------------------------------------------------------------------------------- */
+
+struct str_Ulb {
+ int a1;
+ int a2;
+ struct str1 a3;
+ struct str1 (*f3)(int , int , int , int );
+ int i13, j13, i23, j23;
+};
+
+struct str_Hybrid *new_Ulb(int a1, int a2, struct str1 (*f3)(int , int , int , int ), int i13, int j13, int i23, int j23)
+{
+ struct str_Ulb *t;
+
+ t=(struct str_Ulb *) calloc(1, sizeof(struct str_Ulb ));
+ t->a1 = a1;
+ t->a2 = a2;
+ t->f3 = f3;
+ t->i13 = i13;
+ t->j13 = j13;
+ t->i23 = i23;
+ t->j23 = j23;
+ return(new_Hybrid(SIGID_Ulb, t));
+}
+
+
+/* operator Eds */
+/* -------------------------------------------------------------------------------- */
+
+struct str_Eds {
+ int a1;
+ int a2;
+ struct str1 a3;
+ struct str1 (*f3)(int , int , int , int );
+ int i13, j13, i23, j23;
+};
+
+struct str_Hybrid *new_Eds(int a1, int a2, struct str1 (*f3)(int , int , int , int ), int i13, int j13, int i23, int j23)
+{
+ struct str_Eds *t;
+
+ t=(struct str_Eds *) calloc(1, sizeof(struct str_Eds ));
+ t->a1 = a1;
+ t->a2 = a2;
+ t->f3 = f3;
+ t->i13 = i13;
+ t->j13 = j13;
+ t->i23 = i23;
+ t->j23 = j23;
+ return(new_Hybrid(SIGID_Eds, t));
+}
+
+
+/* operator Edt */
+/* -------------------------------------------------------------------------------- */
+
+struct str_Edt {
+ int a1;
+ int a2;
+ struct str1 a3;
+ struct str1 (*f3)(int , int , int , int );
+ int i13, j13, i23, j23;
+};
+
+struct str_Hybrid *new_Edt(int a1, int a2, struct str1 (*f3)(int , int , int , int ), int i13, int j13, int i23, int j23)
+{
+ struct str_Edt *t;
+
+ t=(struct str_Edt *) calloc(1, sizeof(struct str_Edt ));
+ t->a1 = a1;
+ t->a2 = a2;
+ t->f3 = f3;
+ t->i13 = i13;
+ t->j13 = j13;
+ t->i23 = i23;
+ t->j23 = j23;
+ return(new_Hybrid(SIGID_Edt, t));
+}
+
+
+/* operator Edb */
+/* -------------------------------------------------------------------------------- */
+
+struct str_Edb {
+ int a1;
+ int a2;
+ struct str1 a3;
+ struct str1 (*f3)(int , int , int , int );
+ int i13, j13, i23, j23;
+};
+
+struct str_Hybrid *new_Edb(int a1, int a2, struct str1 (*f3)(int , int , int , int ), int i13, int j13, int i23, int j23)
+{
+ struct str_Edb *t;
+
+ t=(struct str_Edb *) calloc(1, sizeof(struct str_Edb ));
+ t->a1 = a1;
+ t->a2 = a2;
+ t->f3 = f3;
+ t->i13 = i13;
+ t->j13 = j13;
+ t->i23 = i23;
+ t->j23 = j23;
+ return(new_Hybrid(SIGID_Edb, t));
+}
+
+
+/* operator Sr */
+/* -------------------------------------------------------------------------------- */
+
+struct str_Sr {
+ int a1;
+ int a2;
+ struct str1 a3;
+ struct str1 (*f3)(int , int , int , int );
+ int i13, j13, i23, j23;
+};
+
+struct str_Hybrid *new_Sr(int a1, int a2, struct str1 (*f3)(int , int , int , int ), int i13, int j13, int i23, int j23)
+{
+ struct str_Sr *t;
+
+ t=(struct str_Sr *) calloc(1, sizeof(struct str_Sr ));
+ t->a1 = a1;
+ t->a2 = a2;
+ t->f3 = f3;
+ t->i13 = i13;
+ t->j13 = j13;
+ t->i23 = i23;
+ t->j23 = j23;
+ return(new_Hybrid(SIGID_Sr, t));
+}
+
+
+/* operator Bt */
+/* -------------------------------------------------------------------------------- */
+
+struct str_Bt {
+ int a1;
+ int a2;
+ int a3;
+ int a4;
+ int a5;
+ struct str1 a6;
+ struct str1 (*f6)(int , int , int , int );
+ int i16, j16, i26, j26;
+};
+
+struct str_Hybrid *new_Bt(int a1, int a2, int a3, int a4, int a5, struct str1 (*f6)(int , int , int , int ), int i16, int j16, int i26, int j26)
+{
+ struct str_Bt *t;
+
+ t=(struct str_Bt *) calloc(1, sizeof(struct str_Bt ));
+ t->a1 = a1;
+ t->a2 = a2;
+ t->a3 = a3;
+ t->a4 = a4;
+ t->a5 = a5;
+ t->f6 = f6;
+ t->i16 = i16;
+ t->j16 = j16;
+ t->i26 = i26;
+ t->j26 = j26;
+ return(new_Hybrid(SIGID_Bt, t));
+}
+
+
+/* operator Bb */
+/* -------------------------------------------------------------------------------- */
+
+struct str_Bb {
+ int a1;
+ int a2;
+ int a3;
+ int a4;
+ int a5;
+ struct str1 a6;
+ struct str1 (*f6)(int , int , int , int );
+ int i16, j16, i26, j26;
+};
+
+struct str_Hybrid *new_Bb(int a1, int a2, int a3, int a4, int a5, struct str1 (*f6)(int , int , int , int ), int i16, int j16, int i26, int j26)
+{
+ struct str_Bb *t;
+
+ t=(struct str_Bb *) calloc(1, sizeof(struct str_Bb ));
+ t->a1 = a1;
+ t->a2 = a2;
+ t->a3 = a3;
+ t->a4 = a4;
+ t->a5 = a5;
+ t->f6 = f6;
+ t->i16 = i16;
+ t->j16 = j16;
+ t->i26 = i26;
+ t->j26 = j26;
+ return(new_Hybrid(SIGID_Bb, t));
+}
+
+
+/* operator Il */
+/* -------------------------------------------------------------------------------- */
+
+struct str_Il {
+ int a1;
+ int a2;
+ int a3;
+ int a4;
+ int a5;
+ int a6;
+ struct str1 a7;
+ struct str1 (*f7)(int , int , int , int );
+ int i17, j17, i27, j27;
+};
+
+struct str_Hybrid *new_Il(int a1, int a2, int a3, int a4, int a5, int a6, struct str1 (*f7)(int , int , int , int ), int i17, int j17, int i27, int j27)
+{
+ struct str_Il *t;
+
+ t=(struct str_Il *) calloc(1, sizeof(struct str_Il ));
+ t->a1 = a1;
+ t->a2 = a2;
+ t->a3 = a3;
+ t->a4 = a4;
+ t->a5 = a5;
+ t->a6 = a6;
+ t->f7 = f7;
+ t->i17 = i17;
+ t->j17 = j17;
+ t->i27 = i27;
+ t->j27 = j27;
+ return(new_Hybrid(SIGID_Il, t));
+}
+
+/* operator El */
+/* -------------------------------------------------------------------------------- */
+
+struct str_El {
+ int a1;
+ int a2;
+ int a3;
+ int a4;
+ int a5;
+ int a6;
+};
+
+struct str_Hybrid *new_El(int a1, int a2, int a3, int a4, int a5, int a6)
+{
+ struct str_El *t;
+
+ t=(struct str_El *) calloc(1, sizeof(struct str_El ));
+ t->a1 = a1;
+ t->a2 = a2;
+ t->a3 = a3;
+ t->a4 = a4;
+ t->a5 = a5;
+ t->a6 = a6;
+ return(new_Hybrid(SIGID_El, t));
+}
+
+
+/* operator Nil */
+/* -------------------------------------------------------------------------------- */
+
+struct str_Nil {
+ int a1;
+ int a2;
+ int a3;
+ int a4;
+};
+
+struct str_Hybrid *new_Nil(int a1, int a2, int a3, int a4)
+{
+ struct str_Nil *t;
+
+ t=(struct str_Nil *) calloc(1, sizeof(struct str_Nil ));
+ t->a1 = a1;
+ t->a2 = a2;
+ t->a3 = a3;
+ t->a4 = a4;
+ return(new_Hybrid(SIGID_Nil, t));
+};
+
+
+/* signature pretty printer */
+/* -------------------------------------------------------------------------------- */
+
+/* int gx; */
+/* char *t1, *t2, *t3, *t4; */
+/* char *r1, *r2, *r3, *r4; */
+
+/* int a1, a2, a3, a4, a5, a6; */
+
+char *sx(char *t, int i)
+{
+ if (x[i]==A) t[0]='A'; else
+ if (x[i]==C) t[0]='C'; else
+ if (x[i]==G) t[0]='G'; else
+ if (x[i]==U) t[0]='U'; else
+ t[0]='N';
+ t[1]=0;
+ return(&t[1]);
+}
+
+char *shift(char *t, int u, int v)
+{
+ if ((v-u)==0) {t[0]=' '; t[1] = ' '; t[2] = 0; return(&t[2]);}
+ else {t[0]=' '; t[1] = 0; return(&t[1]);}
+}
+
+char *one_space(char *t)
+{
+ t[0]=' '; t[1] = 0; return(&t[1]);
+}
+
+
+char *ssx(char *t, int i, int j)
+{
+ int k;
+ for (k=i+1;k<=j;k++) t=sx(t,k);
+ return(&t[0]);
+}
+
+
+char *sy(char *t, int i)
+{
+ if (y[i]==A) t[0]='A'; else
+ if (y[i]==C) t[0]='C'; else
+ if (y[i]==G) t[0]='G'; else
+ if (y[i]==U) t[0]='U'; else
+ t[0]='N';
+ t[1]=0;
+ return(&t[1]);
+}
+
+char *ssy(char *t, int i, int j)
+{
+ int k;
+ for (k=i+1;k<=j;k++) t=sy(t,k);
+ return(&t[0]);
+}
+
+
+char *blanks(char *t, int i, int j)
+{
+ int k,l;
+ l=j-i;
+ for (k=0;k<=l-1;k++) t[k]=' ';
+ t[l]=0;
+ return(&t[l]);
+}
+
+char *blanks2(char *t, int i, int j)
+{
+ int k,l;
+ l=max(j-i-1,0);
+ for (k=0;k<=l-1;k++) t[k]=' ';
+ t[l]=0;
+ return(&t[l]);
+}
+
+char *asym1(char *t, int l,int r,int u,int v)
+{
+ int k,ln;
+ ln=max((v-u)-(r-l),0);
+ for (k=0;k<=ln-1;k++) t[k]=' ';
+ t[ln]=0;
+ return(&t[ln]);
+}
+
+char *asym2(char *t, int l,int r,int u,int v)
+{
+ int k,ln;
+ ln=max((r-l)-(v-u),0);
+ for (k=0;k<=ln-1;k++) t[k]=' ';
+ t[ln]=0;
+ return(&t[ln]);
+}
+
+
+void pp_str_Hybrid(struct str1 l)
+{
+ struct str_Hybrid *c;
+
+ c = l.alg_enum;
+
+ if (c->utype == SIGID__NTID) {
+ pp_str_Hybrid(((struct str__NTID *)(c->entry))->a1);
+ } else
+ if (c->utype == SIGID_Ult) {
+/* gx++; */
+ pp_str_Hybrid(((struct str_Ult *)(c->entry))->a3);
+ } else
+ if (c->utype == SIGID_Ulb) {
+ r1 = one_space(r1);
+ r2 = one_space(r2);
+ r3 = one_space(r3);
+ a2 =((struct str_Ulb *)(c->entry))->a2;
+ r4 = sy(r4,a2);
+ pp_str_Hybrid(((struct str_Ulb *)(c->entry))->a3);
+ } else
+ if (c->utype == SIGID_Eds) {
+ a1=((struct str_Eds *)(c->entry))->a1;
+ a2=((struct str_Eds *)(c->entry))->a2;
+ r1 = sx(r1,a1);
+ r2 = one_space(r2);
+ r3 = one_space(r3);
+ r4 = sy(r4,a2);
+ pp_str_Hybrid(((struct str_Eds *)(c->entry))->a3);
+ } else
+ if (c->utype == SIGID_Edt) {
+ a1=((struct str_Edt *)(c->entry))->a1;
+ r1 = sx(r1,a1);
+ r2 = one_space(r2);
+ r3 = one_space(r3);
+ r4 = one_space(r4);
+ pp_str_Hybrid(((struct str_Edt *)(c->entry))->a3);
+ } else
+ if (c->utype == SIGID_Edb) {
+ a2=((struct str_Edb *)(c->entry))->a2;
+ r1 = one_space(r1);
+ r2 = one_space(r2);
+ r3 = one_space(r3);
+ r4 = sy(r4,a2);
+ pp_str_Hybrid(((struct str_Edb *)(c->entry))->a3);
+ } else
+ if (c->utype == SIGID_Sr) {
+ a1=((struct str_Sr *)(c->entry))->a1;
+ a2=((struct str_Sr *)(c->entry))->a2;
+ r1 = one_space(r1);
+ r2 = sx(r2,a1);
+ r3 = sy(r3,a2);
+ r4 = one_space(r4);
+ pp_str_Hybrid(((struct str_Sr *)(c->entry))->a3);
+ } else
+ if (c->utype == SIGID_Bt) {
+ a1=((struct str_Bt *)(c->entry))->a1;
+ a2=((struct str_Bt *)(c->entry))->a2;
+ a3=((struct str_Bt *)(c->entry))->a3;
+ a4=((struct str_Bt *)(c->entry))->a4;
+ r1 = one_space(r1);
+ r1 = ssx(r1,a3,a4);
+ r2 = sx(r2,a1);
+ r2 = blanks(r2,a3,a4);
+ r3 = sy(r3,a2);
+ r3 = blanks(r3,a3,a4);
+ r4 = one_space(r4);
+ r4 = blanks(r4,a3,a4);
+ pp_str_Hybrid(((struct str_Bt *)(c->entry))->a6);
+ } else
+ if (c->utype == SIGID_Bb) {
+ a1=((struct str_Bb *)(c->entry))->a1;
+ a2=((struct str_Bb *)(c->entry))->a2;
+ a3=((struct str_Bb *)(c->entry))->a3;
+ a4=((struct str_Bb *)(c->entry))->a4;
+ a5=((struct str_Bb *)(c->entry))->a5;
+
+ r1 = one_space(r1);
+ r1 = blanks(r1,a4,a5);
+ r2 = sx(r2,a1);
+ r2 = blanks(r2,a4,a5);
+ r3 = sy(r3,a2);
+ r3 = blanks(r3,a4,a5);
+ r4 = one_space(r4);
+ r4 = ssy(r4,a4,a5);
+ pp_str_Hybrid(((struct str_Bb *)(c->entry))->a6);
+ } else
+ if (c->utype == SIGID_Il) {
+ a1=((struct str_Il *)(c->entry))->a1;
+ a2=((struct str_Il *)(c->entry))->a2;
+ a3=((struct str_Il *)(c->entry))->a3;
+ a4=((struct str_Il *)(c->entry))->a4;
+ a5=((struct str_Il *)(c->entry))->a5;
+ a6=((struct str_Il *)(c->entry))->a6;
+
+ r1 = one_space(r1);
+ r1 = ssx(r1,a3,a4);
+ r1 = asym1(r1,a3,a4,a5,a6);
+
+ r2 = sx(r2,a1);
+ r2 = blanks(r2,a3,a4);
+ r2 = asym1(r2,a3,a4,a5,a6);
+
+ r3 = sy(r3,a2);
+ r3 = blanks(r3,a5,a6);
+ r3 = asym2(r3,a3,a4,a5,a6);
+
+ r4 = one_space(r4);
+ r4 = ssy(r4,a5,a6);
+ r4 = asym2(r4,a3,a4,a5,a6);
+
+ pp_str_Hybrid(((struct str_Il *)(c->entry))->a7);
+ } else
+ if (c->utype == SIGID_El) {
+ a1=((struct str_El *)(c->entry))->a1;
+ a2=((struct str_El *)(c->entry))->a2;
+ a3=((struct str_El *)(c->entry))->a3;
+ a4=((struct str_El *)(c->entry))->a4;
+ a5=((struct str_El *)(c->entry))->a5;
+ a6=((struct str_El *)(c->entry))->a6;
+ if ((a4-a3) == 0) {
+ r1 = one_space(r1);
+ r1 = blanks(r1,a5,a6);
+
+ r2 = sx(r2,a3);
+ r2 = blanks(r2,a5,a6);
+
+ r3 = sy(r3,a5);
+ r3 = blanks(r3,a5,a6);
+
+ r4 = one_space(r4);
+ r4 = ssy(r4,a5,a6);
+ } else {
+ r1 = one_space(r1);
+ r1 = sx(r1,a3+1);
+ r1 = blanks2(r1,a5,a6);
+
+ r2 = sx(r2,a3);
+ r2 = one_space(r2);
+ r2 = blanks2(r2,a5,a6);
+
+ r3 = sy(r3,a5);
+ r3 = one_space(r3);
+ r3 = blanks2(r3,a5,a6);
+
+ r4 = shift(r4,a5,a6);
+ r4 = ssy(r4,a5,a6);
+ }
+ } else
+ if (c->utype == SIGID_Nil) {
+ r1[0] = '\0';
+ r2[0] = '\0';
+ r3[0] = '\0';
+ r4[0] = '\0';
+ }
+}
+
+
+/* free structures */
+/* -------------------------------------------------------------------------------- */
+
+void free_str_Hybrid(struct str_Hybrid *c)
+{
+ struct str1 l, l2;
+
+ if (c != NULL) {
+ if (c->utype == SIGID__NTID) {
+ l = ((struct str__NTID *)(c->entry))->a1;
+ free_str_Hybrid(l.alg_enum);
+ free(c->entry);
+ } else
+ if (c->utype == SIGID_Ult) {
+ l = ((struct str_Ult *)(c->entry))->a3;
+ free_str_Hybrid(l.alg_enum);
+ free(c->entry);
+ } else
+ if (c->utype == SIGID_Ulb) {
+ l = ((struct str_Ulb *)(c->entry))->a3;
+ free_str_Hybrid(l.alg_enum);
+ free(c->entry);
+ } else
+ if (c->utype == SIGID_Eds) {
+ l = ((struct str_Eds *)(c->entry))->a3;
+ free_str_Hybrid(l.alg_enum);
+ free(c->entry);
+ } else
+ if (c->utype == SIGID_Edt) {
+ l = ((struct str_Edt *)(c->entry))->a3;
+ free_str_Hybrid(l.alg_enum);
+ free(c->entry);
+ } else
+ if (c->utype == SIGID_Edb) {
+ l = ((struct str_Edb *)(c->entry))->a3;
+ free_str_Hybrid(l.alg_enum);
+ free(c->entry);
+ } else
+ if (c->utype == SIGID_Sr) {
+ l = ((struct str_Sr *)(c->entry))->a3;
+ free_str_Hybrid(l.alg_enum);
+ free(c->entry);
+ } else
+ if (c->utype == SIGID_Bt) {
+ l = ((struct str_Bt *)(c->entry))->a6;
+ free_str_Hybrid(l.alg_enum);
+ free(c->entry);
+ } else
+ if (c->utype == SIGID_Bb) {
+ l = ((struct str_Bb *)(c->entry))->a6;
+ free_str_Hybrid(l.alg_enum);
+ free(c->entry);
+ } else
+ if (c->utype == SIGID_Il) {
+ l = ((struct str_Il *)(c->entry))->a7;
+ free_str_Hybrid(l.alg_enum);
+ free(c->entry);
+ } else
+ if (c->utype == SIGID_El) {
+ free(c->entry);
+ } else
+ if (c->utype == SIGID_Nil) {
+ free(c->entry);
+ }
+ }
+ free(c);
+}
+
+/* structure builder */
+/* -------------------------------------------------------------------------------- */
+
+struct str1 build_str_Hybrid(struct str1 cl)
+{
+ struct str1 l;
+ struct str_Hybrid *c;
+
+ c = cl.alg_enum;
+ if (c->utype == SIGID__NTID) {
+ ((struct str__NTID *)(c->entry))->a1 = (*((struct str__NTID *)(c->entry))->f1)(((struct str__NTID *)(c->entry))->i11, ((struct str__NTID *)(c->entry))->j11, ((struct str__NTID *)(c->entry))->i21, ((struct str__NTID *)(c->entry))->j21);
+ } else
+ if (c->utype == SIGID_Ult) {
+ ((struct str_Ult *)(c->entry))->a3 = (*((struct str_Ult *)(c->entry))->f3)(((struct str_Ult *)(c->entry))->i13, ((struct str_Ult *)(c->entry))->j13, ((struct str_Ult *)(c->entry))->i23, ((struct str_Ult *)(c->entry))->j23);
+ } else
+ if (c->utype == SIGID_Ulb) {
+ ((struct str_Ulb *)(c->entry))->a3 = (*((struct str_Ulb *)(c->entry))->f3)(((struct str_Ulb *)(c->entry))->i13, ((struct str_Ulb *)(c->entry))->j13, ((struct str_Ulb *)(c->entry))->i23, ((struct str_Ulb *)(c->entry))->j23);
+ } else
+ if (c->utype == SIGID_Eds) {
+ ((struct str_Eds *)(c->entry))->a3 = (*((struct str_Eds *)(c->entry))->f3)(((struct str_Eds *)(c->entry))->i13, ((struct str_Eds *)(c->entry))->j13, ((struct str_Eds *)(c->entry))->i23, ((struct str_Eds *)(c->entry))->j23);
+ } else
+ if (c->utype == SIGID_Edt) {
+ ((struct str_Edt *)(c->entry))->a3 = (*((struct str_Edt *)(c->entry))->f3)(((struct str_Edt *)(c->entry))->i13, ((struct str_Edt *)(c->entry))->j13, ((struct str_Edt *)(c->entry))->i23, ((struct str_Edt *)(c->entry))->j23);
+ } else
+ if (c->utype == SIGID_Edb) {
+ ((struct str_Edb *)(c->entry))->a3 = (*((struct str_Edb *)(c->entry))->f3)(((struct str_Edb *)(c->entry))->i13, ((struct str_Edb *)(c->entry))->j13, ((struct str_Edb *)(c->entry))->i23, ((struct str_Edb *)(c->entry))->j23);
+ } else
+ if (c->utype == SIGID_Sr) {
+ ((struct str_Sr *)(c->entry))->a3 = (*((struct str_Sr *)(c->entry))->f3)(((struct str_Sr *)(c->entry))->i13, ((struct str_Sr *)(c->entry))->j13, ((struct str_Sr *)(c->entry))->i23, ((struct str_Sr *)(c->entry))->j23);
+ } else
+ if (c->utype == SIGID_Bt) {
+ ((struct str_Bt *)(c->entry))->a6 = (*((struct str_Bt *)(c->entry))->f6)(((struct str_Bt *)(c->entry))->i16, ((struct str_Bt *)(c->entry))->j16, ((struct str_Bt *)(c->entry))->i26, ((struct str_Bt *)(c->entry))->j26);
+ } else
+ if (c->utype == SIGID_Bb) {
+ ((struct str_Bb *)(c->entry))->a6 = (*((struct str_Bb *)(c->entry))->f6)(((struct str_Bb *)(c->entry))->i16, ((struct str_Bb *)(c->entry))->j16, ((struct str_Bb *)(c->entry))->i26, ((struct str_Bb *)(c->entry))->j26);
+ } else
+ if (c->utype == SIGID_Il) {
+ ((struct str_Il *)(c->entry))->a7 = (*((struct str_Il *)(c->entry))->f7)(((struct str_Il *)(c->entry))->i17, ((struct str_Il *)(c->entry))->j17, ((struct str_Il *)(c->entry))->i27, ((struct str_Il *)(c->entry))->j27);
+ } else
+ if (c->utype == SIGID_El) {
+ } else
+ if (c->utype == SIGID_Nil) {
+ }
+ return(cl);
+}
+
+/* table declarations */
+/* -------------------------------------------------------------------------------- */
+
+double **tbl_unpaired_left_top;
+double **tbl_unpaired_left_bot;
+double **tbl_closed;
+
+/* forward declarations */
+/* -------------------------------------------------------------------------------- */
+
+double calc_hybrid(int i1, int j1, int i2, int j2);
+
+/* table calculations */
+/* -------------------------------------------------------------------------------- */
+
+/* table calculation for production hybrid */
+/* -------------------------------------------------------------------------------- */
+
+double calc_hybrid(int i1, int j1, int i2, int j2)
+{
+ double v1, v2, v3, v4, v5;
+
+ /* ---------------------------------- start of --------------------------------- */
+ /* --------------------- v1 = nil <<< tt(uregion, uregion) --------------------- */
+ if (((j1-i1) >= 0) && ((j2-i2) >= 0)) {
+ v1 = 0;
+ /* No iteration neccessary! */
+ }
+ else {
+ v1 = 65000;
+ }
+ /* --------------------- v1 = nil <<< tt(uregion, uregion) --------------------- */
+ /* ---------------------------------- finished --------------------------------- */
+
+ /* -------------------------- v2 = p unpaired_left_top ------------------------- */
+ if (((j1-i1) >= 1) && ((j2-i2) >= 1)) {
+ v2 = tbl_unpaired_left_top[i1][i2];
+ }
+ else {
+ v2 = 65000;
+ }
+ /* ------------------------------- v3 = p closed ------------------------------- */
+ if (((j1-i1) >= 1) && ((j2-i2) >= 1)) {
+ v3 = tbl_closed[i1][i2];
+ }
+ else {
+ v3 = 65000;
+ }
+ v4 = v2 < v3 ? v2 : v3;
+ v5 = v1 < v4 ? v1 : v4;
+ return(v5);
+}
+
+/* table calculation for production unpaired_left_top */
+/* -------------------------------------------------------------------------------- */
+
+void calc_unpaired_left_top(int i1, int j1, int i2, int j2)
+{
+ double v1, v2, v3;
+
+ /* ---------------------------------- start of --------------------------------- */
+ /* ---------- v1 = ult <<< (tt(lbase, empty)) ~~~ p unpaired_left_top ---------- */
+ if (((j1-i1) >= 2) && ((j2-i2) >= 1)) {
+ v1 = tbl_unpaired_left_top[i1+1][i2];
+ /* No iteration neccessary! */
+ }
+ else {
+ v1 = 65000;
+ }
+ /* ---------- v1 = ult <<< (tt(lbase, empty)) ~~~ p unpaired_left_top ---------- */
+ /* ---------------------------------- finished --------------------------------- */
+
+ /* -------------------------- v2 = p unpaired_left_bot ------------------------- */
+ if (((j1-i1) >= 1) && ((j2-i2) >= 1) && ((i2 < helix_start) || (i2 >= helix_end))) {
+ v2 = tbl_unpaired_left_bot[i1][i2];
+ }
+ else {
+ v2 = 65000;
+ }
+ v3 = v1 < v2 ? v1 : v2;
+ /* ------------------------- assign table entry result ------------------------- */
+ if (((j1-i1) >= 1) && ((j2-i2) >= 1)) {
+ tbl_unpaired_left_top[i1][i2] = v3;
+ }
+}
+
+/* table calculation for production unpaired_left_bot */
+/* -------------------------------------------------------------------------------- */
+
+void calc_unpaired_left_bot(int i1, int j1, int i2, int j2)
+{
+ double v1, v2, v3, v4, v5, v6, v7;
+
+ /* ---------------------------------- start of --------------------------------- */
+ /* ---------- v1 = ulb <<< (tt(empty, lbase)) ~~~ p unpaired_left_bot ---------- */
+ if (((j1-i1) >= 1) && ((j2-i2) >= 2) && ((i2 < helix_start-1) || (i2 >= helix_end))) {
+ v1 = tbl_unpaired_left_bot[i1][i2+1];
+ /* No iteration neccessary! */
+ }
+ else {
+ v1 = 65000;
+ }
+ /* ---------- v1 = ulb <<< (tt(empty, lbase)) ~~~ p unpaired_left_bot ---------- */
+ /* ---------------------------------- finished --------------------------------- */
+
+ /* ---------------------------------- start of --------------------------------- */
+ /* ---------------- v2 = eds <<< (tt(lbase, lbase)) ~~~ p closed --------------- */
+ if (((j1-i1) >= 2) && ((j2-i2) >= 2) && compl(x[i1+2],y[i2+2]) && ((i2 < helix_start) || (i2 >= helix_end))) {
+ v2 = (tbl_closed[i1+1][i2+1] + dl_energy((i1+1) + 1, (i2+1) + 1)) + dr_energy((i1+1) + 1, (i2+1) + 1);
+ /* No iteration neccessary! */
+ }
+ else {
+ v2 = 65000;
+ }
+ /* ---------------- v2 = eds <<< (tt(lbase, lbase)) ~~~ p closed --------------- */
+ /* ---------------------------------- finished --------------------------------- */
+
+ /* ---------------------------------- start of --------------------------------- */
+ /* ---------------- v3 = edt <<< (tt(lbase, empty)) ~~~ p closed --------------- */
+ if (((j1-i1) >= 2) && ((j2-i2) >= 1) && compl(x[i1+2],y[i2+1])) {
+ v3 = tbl_closed[i1+1][i2] + dl_energy((i1+1) + 1, (i2) + 1);
+ /* No iteration neccessary! */
+ }
+ else {
+ v3 = 65000;
+ }
+ /* ---------------- v3 = edt <<< (tt(lbase, empty)) ~~~ p closed --------------- */
+ /* ---------------------------------- finished --------------------------------- */
+
+ /* ---------------------------------- start of --------------------------------- */
+ /* ---------------- v4 = edb <<< (tt(empty, lbase)) ~~~ p closed --------------- */
+ if (((j1-i1) >= 1) && ((j2-i2) >= 2) && compl(x[i1+1],y[i2+2]) && ((i2 < helix_start) || (i2 >= helix_end))) {
+ v4 = tbl_closed[i1][i2+1] + dr_energy((i1) + 1, (i2+1) + 1);
+ /* No iteration neccessary! */
+ }
+ else {
+ v4 = 65000;
+ }
+ /* ---------------- v4 = edb <<< (tt(empty, lbase)) ~~~ p closed --------------- */
+ /* ---------------------------------- finished --------------------------------- */
+
+ v5 = v3 < v4 ? v3 : v4;
+ v6 = v2 < v5 ? v2 : v5;
+ v7 = v1 < v6 ? v1 : v6;
+ /* ------------------------- assign table entry result ------------------------- */
+ if (((j1-i1) >= 1) && ((j2-i2) >= 1)) {
+ tbl_unpaired_left_bot[i1][i2] = v7;
+ }
+}
+
+/* table calculation for production closed */
+/* -------------------------------------------------------------------------------- */
+
+void calc_closed(int i1, int j1, int i2, int j2)
+{
+ double v1, v2, v3, v4, v5, v6, v7, v7b, v7c, v7d, v7e, v7f, v7g, v8, v9, v10, v11, v12;
+ int k;
+ int k2;
+ int k3;
+ int k4;
+
+ /* ---------------------------------- start of --------------------------------- */
+ /* - v1 = sr <<< (tt(lbase, lbase) `with` (pairingTTcross compl)) ~~~ p closed - */
+ if (((j1-i1) >= 2) && ((j2-i2) >= 2)) {
+ if (compl(x[i1+1], y[i2+1])) {
+ v1 = sr_energy(i1+1, i2+1) + tbl_closed[i1+1][i2+1];
+ /* No iteration neccessary! */
+ }
+ else {
+ v1 = 65000;
+ }
+ }
+ else {
+ v1 = 65000;
+ }
+ /* - v1 = sr <<< (tt(lbase, lbase) `with` (pairingTTcross compl)) ~~~ p closed - */
+ /* ---------------------------------- finished --------------------------------- */
+
+ /* ---------------------------------- start of --------------------------------- */
+ /* v3 = bt <<< (tt(lbase, lbase) `with` (pairingTTcross compl)) ~~~ (tt(region, empty) `with` (sizeTT 1 15 0 0)) ~~~ p closed */
+ if (((j1-i1) >= 3) && ((j2-i2) >= 2) && compl(x[i1+1], y[i2+1]) && ((i2 < helix_start) || (i2 >= helix_end-1))) {
+ v3 = 65000;
+ for (k=i1+2; k<=min(i1+bloop_upper_limit+1, j1-1); k++) {
+ if (x[k]==X)
+ break;
+ v2 = (tbl_closed[k][i2+1] + bl_stacking((k) - (i1+1), 0, i1+1, i2+1)) + bl_ent((k) - (i1+1));
+ /* No iteration neccessary! */
+ v3 = v2 < v3 ? v2 : v3;
+ }
+ }
+ else {
+ v3 = 65000;
+ }
+ /* v3 = bt <<< (tt(lbase, lbase) `with` (pairingTTcross compl)) ~~~ (tt(region, empty) `with` (sizeTT 1 15 0 0)) ~~~ p closed */
+ /* ---------------------------------- finished --------------------------------- */
+
+ /* ---------------------------------- start of --------------------------------- */
+ /* v5 = bb <<< (tt(lbase, lbase) `with` (pairingTTcross compl)) ~~~ (tt(empty, region) `with` (sizeTT 0 0 1 15)) ~~~ p closed */
+ if (((j1-i1) >= 2) && ((j2-i2) >= 3) & compl(x[i1+1], y[i2+1])) {
+ v5 = 65000;
+ for (k2=i2+2; k2<=min(i2+bloop_upper_limit+1, j2-1); k2++) {
+ if ((k2 > helix_start) && (k2 <= helix_end))
+ break;
+ v4 = (tbl_closed[i1+1][k2] + bl_stacking(0, (k2) - (i2+1), i1+1, i2+1)) + bl_ent((k2) - (i2+1));
+ /* No iteration neccessary! */
+ v5 = v4 < v5 ? v4 : v5;
+ }
+ }
+ else {
+ v5 = 65000;
+ }
+ /* v5 = bb <<< (tt(lbase, lbase) `with` (pairingTTcross compl)) ~~~ (tt(empty, region) `with` (sizeTT 0 0 1 15)) ~~~ p closed */
+ /* ---------------------------------- finished --------------------------------- */
+
+ /* ---------------------------------- start of --------------------------------- */
+ /* v7 = il <<< (tt(lbase, lbase) `with` (pairingTTcross compl)) ~~~ (tt(region, region) `with` (sizeTT 1 15 1 15)) ~~~ p closed */
+
+ if (((j1-i1) >= 3) && ((j2-i2) >= 3) && compl(x[i1+1], y[i2+1])) {
+ v7 = 65000;
+ /* special internal loops: */
+ for (k3=i1+2; k3<=min(i1+min(3,iloop_upper_limit+1), j1-1); k3++) {
+ if (x[k3]==X)
+ break;
+ for (k4=i2+2; k4<=min(i2+min(3,iloop_upper_limit+1), j2-1); k4++) {
+ if ((k4 > helix_start) && (i2 < helix_end-1))
+ break;
+ if (compl(x[k3+1],y[k4+1])) {
+ v6 = do_il_special(i1+1, i2+1, i1+1, k3, i2+1, k4, tbl_closed[k3][k4]);
+ /* No iteration neccessary! */
+ v7 = v6 < v7 ? v6 : v7;
+ }
+ }
+ }
+ v7g = 65000;
+ v7b = 65000;
+ if ((x[k3]!=X)) { /* && !((k4 > helix_start) && (i2 < helix_end-1))) { */
+ /* normal internal loops: */
+ for (k3=i1+2; k3<=min(i1+3, j1-1); k3++) {
+ if (x[k3]==X)
+ break;
+ for (k4=i2+4; k4<=min(i2+iloop_upper_limit+1, j2-1); k4++) {
+ if ((k4 > helix_start) && (i2 < helix_end-1))
+ break;
+ if (compl(x[k3+1],y[k4+1])) {
+ v6 = do_il(i1+1, i2+1, i1+1, k3, i2+1, k4, tbl_closed[k3][k4]);
+ /* No iteration neccessary! */
+ v7b = v6 < v7b ? v6 : v7b;
+ }
+ }
+ }
+ if (v7b < 65000)
+ v7b += il_stack_open(i1+1,i2+1);
+ v7c = 65000;
+ /* normal internal loops: */
+ if ((x[k3]!=X)) { /* && !((k4 > helix_start) && (i2 < helix_end-1))) { */
+ for (k3=i1+4; k3<=min(i1+iloop_upper_limit+1, j1-1); k3++) {
+ if (x[k3]==X)
+ break;
+ for (k4=i2+2; k4<=min(i2+3, j2-1); k4++) {
+ if ((k4 > helix_start) && (i2 < helix_end-1))
+ break;
+ if (compl(x[k3+1],y[k4+1])) {
+ v6 = do_il(i1+1, i2+1, i1+1, k3, i2+1, k4, tbl_closed[k3][k4]);
+ /* No iteration neccessary! */
+ v7c = v6 < v7c ? v6 : v7c;
+ }
+ }
+ }
+ if (v7c < 65000)
+ v7c += il_stack_open(i1+1,i2+1);
+ v7d = 65000;
+ /* normal internal loops: */
+ if ((x[k3]!=X)) { /* && !((k4 > helix_start) && (i2 < helix_end-1))) { */
+ for (k3=i1+4; k3<=min(i1+iloop_upper_limit+1, j1-1); k3++) {
+ if (x[k3]==X)
+ break;
+ for (k4=i2+4; k4<=min(i2+iloop_upper_limit+1, j2-1); k4++) {
+ if ((k4 > helix_start) && (i2 < helix_end-1))
+ break;
+ if (compl(x[k3+1],y[k4+1])) {
+ v6 = do_il(i1+1, i2+1, i1+1, k3, i2+1, k4, tbl_closed[k3][k4]);
+ /* No iteration neccessary! */
+ v7d = v6 < v7d ? v6 : v7d;
+ }
+ }
+ }
+ if (v7d < 65000)
+ v7d += il_stack_open(i1+1,i2+1);
+ }
+
+ }
+ v7e = v7b < v7c ? v7b : v7c;
+ v7f = v7d < v7e ? v7d : v7e;
+ v7g = v7g < v7f ? v7g : v7f;
+ }
+ v7 = v7g < v7 ? v7g : v7;
+ }
+ else {
+ v7 = 65000;
+ }
+ /* v7 = il <<< (tt(lbase, lbase) `with` (pairingTTcross compl)) ~~~ (tt(region, region) `with` (sizeTT 1 15 1 15)) ~~~ p closed */
+ /* ---------------------------------- finished --------------------------------- */
+
+ /* ---------------------------------- start of --------------------------------- */
+ /* v8 = el <<< (tt(lbase, lbase) `with` (pairingTTcross compl)) ~~~ (tt(uregion, uregion)) */
+ if (((j1-i1) >= 1) && ((j2-i2) >= 1) && (j1==i1+1 || x[i1+2]!='X') && ((i2 >= helix_end-1) || (helix_end > j2))) {
+ if (compl(x[i1+1], y[i2+1])) {
+ v8 = ((((j1) - (i1+1)) > 0) ? dli_energy(i1+1, i2+1) : 0) + ((((j2) - (i2+1)) > 0) ? dri_energy(i1+1, i2+1) : 0);
+ /* No iteration neccessary! */
+ }
+ else {
+ v8 = 65000;
+ }
+ }
+ else {
+ v8 = 65000;
+ }
+ /* v8 = el <<< (tt(lbase, lbase) `with` (pairingTTcross compl)) ~~~ (tt(uregion, uregion)) */
+ /* ---------------------------------- finished --------------------------------- */
+
+
+ v9 = v7 < v8 ? v7 : v8;
+ v10 = v5 < v9 ? v5 : v9;
+ v11 = v3 < v10 ? v3 : v10;
+ v12 = v1 < v11 ? v1 : v11;
+ /* ------------------------- assign table entry result ------------------------- */
+ if (((j1-i1) >= 1) && ((j2-i2) >= 1)) {
+ tbl_closed[i1][i2] = v12;
+ }
+}
+
+/* forward declarations for backtracing functions */
+/* -------------------------------------------------------------------------------- */
+
+struct str1 back_unpaired_left_bot(int i1, int j1, int i2, int j2);
+
+struct str1 back_closed(int i1, int j1, int i2, int j2);
+
+struct str1 back_hybrid(int i1, int j1, int i2, int j2);
+
+/* backtracing code */
+/* -------------------------------------------------------------------------------- */
+
+/* table calculation for production hybrid */
+/* -------------------------------------------------------------------------------- */
+
+struct str1 back_hybrid(int i1, int j1, int i2, int j2)
+{
+ struct str1 v1, v2, v3, v4, v5;
+
+ int k, best_k;
+
+ /* ---------------------------------- start of --------------------------------- */
+ /* --------------------- v1 = nil <<< tt(uregion, uregion) --------------------- */
+ if (((j1-i1) >= 0) && ((j2-i2) >= 0)) {
+ v1.alg_mfe = 0;
+ v1.alg_enum = new_Nil(i1, j1, i2, j2);
+ /* No iteration neccessary! */
+ }
+ else {
+ v1.alg_mfe = 65000;
+ v1.alg_enum = NULL;
+ }
+ /* --------------------- v1 = nil <<< tt(uregion, uregion) --------------------- */
+ /* ---------------------------------- finished --------------------------------- */
+
+ /* -------------------------- v2 = p unpaired_left_top ------------------------- */
+ /* +------------------------------------------------------------------------------------ */
+ /* Nonterminal unpaired_left_top is implemented as a tabulated */
+ /* function which yields atomar results. Since we are in list context, */
+ /* we need to wrap the result of unpaired_left_top into a single list element. */
+ /* +------------------------------------------------------------------------------------ */
+
+
+/* Find best unpaired_left_bot without backtracking recursion to avoid */
+/* stack overflow (hand made): */
+
+ if (((j1-i1) >= 1) && ((j2-i2) >= 1) && ((i2 < helix_start) || (i2 >= helix_end))) {
+
+ v2.alg_mfe = 65000;
+ v2.alg_enum = NULL;
+
+ best_k = -1;
+
+ for (k=i1; k<j1; k++) {
+ if (tbl_unpaired_left_bot[k][i2] < v2.alg_mfe) {
+ v2.alg_mfe = tbl_unpaired_left_bot[k][i2];
+ best_k = k;
+ }
+ }
+
+ if (best_k != -1)
+ v2.alg_enum = new__NTID(back_unpaired_left_bot, best_k, j1, i2, j2);
+
+ }
+ else {
+ v2.alg_mfe = 65000;
+ v2.alg_enum = NULL;
+ }
+
+/* if (((j1-i1) >= 1) && ((j2-i2) >= 1)) { */
+/* v2.alg_mfe = tbl_unpaired_left_top[i1][i2]; */
+/* v2.alg_enum = new__NTID(back_unpaired_left_top, i1, j1, i2, j2); */
+/* } */
+/* else { */
+/* v2.alg_mfe = 65000; */
+/* v2.alg_enum = NULL; */
+/* } */
+
+
+
+
+ /* ------------------------------- v3 = p closed ------------------------------- */
+ /* +---------------------------------------------------------------------------- */
+ /* Nonterminal closed is implemented as a tabulated */
+ /* function which yields atomar results. Since we are in list context, */
+ /* we need to wrap the result of closed into a single list element. */
+ /* +---------------------------------------------------------------------------- */
+ if (((j1-i1) >= 1) && ((j2-i2) >= 1)) {
+ v3.alg_mfe = tbl_closed[i1][i2];
+ v3.alg_enum = new__NTID(back_closed, i1, j1, i2, j2);
+ }
+ else {
+ v3.alg_mfe = 65000;
+ v3.alg_enum = NULL;
+ }
+ /* ---------------------------- v4 = minimum(v2, v3) --------------------------- */
+ if (v2.alg_mfe < v3.alg_mfe) {
+ gx = best_k + 1;
+ v4 = v2;
+ free_str_Hybrid(v3.alg_enum);
+ }
+ else {
+ gx = 0 + 1;
+ v4 = v3;
+ free_str_Hybrid(v2.alg_enum);
+ }
+/* v4 = v2.alg_mfe < v3.alg_mfe ? v2 : v3; */
+ /* ---------------------------- v5 = minimum(v1, v4) --------------------------- */
+ if (v1.alg_mfe < v4.alg_mfe) {
+ gx = 0;
+ v5 = v1;
+ free_str_Hybrid(v4.alg_enum);
+ }
+ else {
+ v5 = v4;
+ free_str_Hybrid(v1.alg_enum);
+ }
+/* v5 = v1.alg_mfe < v4.alg_mfe ? v1 : v4; */
+ /* ------------------------- build candidate structures ------------------------ */
+
+ return(build_str_Hybrid(v5));
+}
+
+/* table calculation for production unpaired_left_top */
+/* -------------------------------------------------------------------------------- */
+
+/* removed after hand made back_hybrid optimisation !*/
+
+
+
+/* table calculation for production unpaired_left_bot */
+/* -------------------------------------------------------------------------------- */
+
+struct str1 back_unpaired_left_bot(int i1, int j1, int i2, int j2)
+{
+ struct str1 v1, v2, v3, v4, v5, v6, v7;
+
+ /* ---------------------------------- start of --------------------------------- */
+ /* ---------- v1 = ulb <<< (tt(empty, lbase)) ~~~ p unpaired_left_bot ---------- */
+ if (((j1-i1) >= 1) && ((j2-i2) >= 2) && ((i2 < helix_start-1) || (i2 >= helix_end))) {
+ v1.alg_mfe = tbl_unpaired_left_bot[i1][i2+1];
+ v1.alg_enum = new_Ulb(i1, i2+1, back_unpaired_left_bot, i1, j1, i2+1, j2);
+ /* No iteration neccessary! */
+ }
+ else {
+ v1.alg_mfe = 65000;
+ v1.alg_enum = NULL;
+ }
+ /* ---------- v1 = ulb <<< (tt(empty, lbase)) ~~~ p unpaired_left_bot ---------- */
+ /* ---------------------------------- finished --------------------------------- */
+
+ /* ---------------------------------- start of --------------------------------- */
+ /* ---------------- v2 = eds <<< (tt(lbase, lbase)) ~~~ p closed --------------- */
+ if (((j1-i1) >= 2) && ((j2-i2) >= 2) && compl(x[i1+2],y[i2+2]) && ((i2 < helix_start) || (i2 >= helix_end))) {
+ v2.alg_mfe = (tbl_closed[i1+1][i2+1] + dl_energy((i1+1) + 1, (i2+1) + 1)) + dr_energy((i1+1) + 1, (i2+1) + 1);
+ v2.alg_enum = new_Eds(i1+1, i2+1, back_closed, i1+1, j1, i2+1, j2);
+ /* No iteration neccessary! */
+ }
+ else {
+ v2.alg_mfe = 65000;
+ v2.alg_enum = NULL;
+ }
+ /* ---------------- v2 = eds <<< (tt(lbase, lbase)) ~~~ p closed --------------- */
+ /* ---------------------------------- finished --------------------------------- */
+
+ /* ---------------------------------- start of --------------------------------- */
+ /* ---------------- v3 = edt <<< (tt(lbase, empty)) ~~~ p closed --------------- */
+ if (((j1-i1) >= 2) && ((j2-i2) >= 1) && compl(x[i1+2],y[i2+1])) {
+ v3.alg_mfe = tbl_closed[i1+1][i2] + dl_energy((i1+1) + 1, (i2) + 1);
+ v3.alg_enum = new_Edt(i1+1, i2, back_closed, i1+1, j1, i2, j2);
+ /* No iteration neccessary! */
+ }
+ else {
+ v3.alg_mfe = 65000;
+ v3.alg_enum = NULL;
+ }
+ /* ---------------- v3 = edt <<< (tt(lbase, empty)) ~~~ p closed --------------- */
+ /* ---------------------------------- finished --------------------------------- */
+
+ /* ---------------------------------- start of --------------------------------- */
+ /* ---------------- v4 = edb <<< (tt(empty, lbase)) ~~~ p closed --------------- */
+ if (((j1-i1) >= 1) && ((j2-i2) >= 2) && compl(x[i1+1],y[i2+2]) && ((i2 < helix_start) || (i2 >= helix_end))) {
+ v4.alg_mfe = tbl_closed[i1][i2+1] + dr_energy((i1) + 1, (i2+1) + 1);
+ v4.alg_enum = new_Edb(i1, i2+1, back_closed, i1, j1, i2+1, j2);
+ /* No iteration neccessary! */
+ }
+ else {
+ v4.alg_mfe = 65000;
+ v4.alg_enum = NULL;
+ }
+ /* ---------------- v4 = edb <<< (tt(empty, lbase)) ~~~ p closed --------------- */
+ /* ---------------------------------- finished --------------------------------- */
+
+ /* ---------------------------- v5 = minimum(v3, v4) --------------------------- */
+ if (v3.alg_mfe < v4.alg_mfe) {
+ v5 = v3;
+ free_str_Hybrid(v4.alg_enum);
+ }
+ else {
+ v5 = v4;
+ free_str_Hybrid(v3.alg_enum);
+ }
+/* v5 = v3.alg_mfe < v4.alg_mfe ? v3 : v4; */
+ /* ---------------------------- v6 = minimum(v2, v5) --------------------------- */
+ if (v2.alg_mfe < v5.alg_mfe) {
+ v6 = v2;
+ free_str_Hybrid(v5.alg_enum);
+ }
+ else {
+ v6 = v5;
+ free_str_Hybrid(v2.alg_enum);
+ }
+/* v6 = v2.alg_mfe < v5.alg_mfe ? v2 : v5; */
+ /* ---------------------------- v7 = minimum(v1, v6) --------------------------- */
+ if (v1.alg_mfe < v6.alg_mfe) {
+ v7 = v1;
+ free_str_Hybrid(v6.alg_enum);
+ }
+ else {
+ v7 = v6;
+ free_str_Hybrid(v1.alg_enum);
+ }
+/* v7 = v1.alg_mfe < v6.alg_mfe ? v1 : v6; */
+ /* ------------------------- build candidate structures ------------------------ */
+
+ return(build_str_Hybrid(v7));
+}
+
+/* table calculation for production closed */
+/* -------------------------------------------------------------------------------- */
+
+struct str1 back_closed(int i1, int j1, int i2, int j2)
+{
+ struct str1 v1, v2, v3, v4, v5, v6, v7, v7b, v7c, v7d, v7e, v7f, v7g, v8, v9, v10, v11, v12;
+ int k;
+ int k2;
+ int k3;
+ int k4;
+
+ /* ---------------------------------- start of --------------------------------- */
+ /* - v1 = sr <<< (tt(lbase, lbase) `with` (pairingTTcross compl)) ~~~ p closed - */
+ if (((j1-i1) >= 2) && ((j2-i2) >= 2)) {
+ if (compl(x[i1+1], y[i2+1])) {
+ v1.alg_mfe = sr_energy(i1+1, i2+1) + tbl_closed[i1+1][i2+1];
+ v1.alg_enum = new_Sr(i1+1, i2+1, back_closed, i1+1, j1, i2+1, j2);
+ /* No iteration neccessary! */
+ }
+ else {
+ v1.alg_mfe = 65000;
+ v1.alg_enum = NULL;
+ }
+ }
+ else {
+ v1.alg_mfe = 65000;
+ v1.alg_enum = NULL;
+ }
+ /* - v1 = sr <<< (tt(lbase, lbase) `with` (pairingTTcross compl)) ~~~ p closed - */
+ /* ---------------------------------- finished --------------------------------- */
+
+ /* ---------------------------------- start of --------------------------------- */
+ /* v3 = bt <<< (tt(lbase, lbase) `with` (pairingTTcross compl)) ~~~ (tt(region, empty) `with` (sizeTT 1 15 0 0)) ~~~ p closed */
+ if (((j1-i1) >= 3) && ((j2-i2) >= 2) && compl(x[i1+1], y[i2+1]) && ((i2 < helix_start) || (i2 >= helix_end-1))) {
+ v3.alg_mfe = 65000;
+ v3.alg_enum = NULL;
+ for (k=i1+2; k<=min(i1+bloop_upper_limit+1, j1-1); k++) {
+ if (x[k]==X)
+ break;
+ v2.alg_mfe = (tbl_closed[k][i2+1] + bl_stacking((k) - (i1+1), 0, i1+1, i2+1)) + bl_ent((k) - (i1+1));
+ v2.alg_enum = new_Bt(i1+1, i2+1, i1+1, k, i2+1, back_closed, k, j1, i2+1, j2);
+ /* No iteration neccessary! */
+ /* ------------------------- v3 = minimum(v2, v3) ------------------------ */
+ if (v2.alg_mfe < v3.alg_mfe) {
+ free_str_Hybrid(v3.alg_enum);
+ v3 = v2;
+ } else free_str_Hybrid(v2.alg_enum);
+ }
+ }
+ else {
+ v3.alg_mfe = 65000;
+ v3.alg_enum = NULL;
+ }
+ /* v3 = bt <<< (tt(lbase, lbase) `with` (pairingTTcross compl)) ~~~ (tt(region, empty) `with` (sizeTT 1 15 0 0)) ~~~ p closed */
+ /* ---------------------------------- finished --------------------------------- */
+
+ /* ---------------------------------- start of --------------------------------- */
+ /* v5 = bb <<< (tt(lbase, lbase) `with` (pairingTTcross compl)) ~~~ (tt(empty, region) `with` (sizeTT 0 0 1 15)) ~~~ p closed */
+ if (((j1-i1) >= 2) && ((j2-i2) >= 3) && compl(x[i1+1], y[i2+1])) {
+ v5.alg_mfe = 65000;
+ v5.alg_enum = NULL;
+ for (k2=i2+2; k2<=min(i2+bloop_upper_limit+1, j2-1); k2++) {
+ if ((k2 > helix_start) && (k2 <= helix_end))
+ break;
+ v4.alg_mfe = (tbl_closed[i1+1][k2] + bl_stacking(0, (k2) - (i2+1), i1+1, i2+1)) + bl_ent((k2) - (i2+1));
+ v4.alg_enum = new_Bb(i1+1, i2+1, i1+1, i2+1, k2, back_closed, i1+1, j1, k2, j2);
+ /* No iteration neccessary! */
+ /* ------------------------- v5 = minimum(v4, v5) ------------------------ */
+ /* v5 = v4.alg_mfe < v5.alg_mfe ? v4 : v5; */
+ if (v4.alg_mfe < v5.alg_mfe) {
+ free_str_Hybrid(v5.alg_enum);
+ v5 = v4;
+ } else free_str_Hybrid(v4.alg_enum);
+ }
+ }
+ else {
+ v5.alg_mfe = 65000;
+ v5.alg_enum = NULL;
+ }
+ /* v5 = bb <<< (tt(lbase, lbase) `with` (pairingTTcross compl)) ~~~ (tt(empty, region) `with` (sizeTT 0 0 1 15)) ~~~ p closed */
+ /* ---------------------------------- finished --------------------------------- */
+
+ /* ---------------------------------- start of --------------------------------- */
+ /* v7 = il <<< (tt(lbase, lbase) `with` (pairingTTcross compl)) ~~~ (tt(region, region) `with` (sizeTT 1 15 1 15)) ~~~ p closed */
+ if (((j1-i1) >= 3) && ((j2-i2) >= 3) && compl(x[i1+1], y[i2+1])) {
+
+ v7.alg_mfe = 65000;
+ v7.alg_enum = NULL;
+ /* special internal loops: */
+ for (k3=i1+2; k3<=min(i1+min(3,iloop_upper_limit+1), j1-1); k3++) {
+ if (x[k3]==X)
+ break;
+ for (k4=i2+2; k4<=min(i2+min(3,iloop_upper_limit+1), j2-1); k4++) {
+ if ((k4 > helix_start) && (i2 < helix_end-1))
+ break;
+ if (compl(x[k3+1],y[k4+1])) {
+ v6.alg_mfe = do_il_special(i1+1, i2+1, i1+1, k3, i2+1, k4, tbl_closed[k3][k4]);
+ v6.alg_enum = new_Il(i1+1, i2+1, i1+1, k3, i2+1, k4, back_closed, k3, j1, k4, j2);
+ /* No iteration neccessary! */
+ if (v6.alg_mfe < v7.alg_mfe) {
+ free_str_Hybrid(v7.alg_enum);
+ v7 = v6;
+ } else free_str_Hybrid(v6.alg_enum);
+ }
+ }
+ }
+ v7g.alg_mfe = 65000;
+ v7g.alg_enum = NULL;
+ v7b.alg_mfe = 65000;
+ v7b.alg_enum = NULL;
+ if ((x[k3]!=X)) { /* && !((k4 > helix_start) && (i2 < helix_end-1))) { */
+
+ /* normal internal loops: */
+ for (k3=i1+2; k3<=min(i1+3, j1-1); k3++) {
+ if (x[k3]==X)
+ break;
+ for (k4=i2+4; k4<=min(i2+iloop_upper_limit+1, j2-1); k4++) {
+ if ((k4 > helix_start) && (i2 < helix_end-1))
+ break;
+ if (compl(x[k3+1],y[k4+1])) {
+ v6.alg_mfe = do_il(i1+1, i2+1, i1+1, k3, i2+1, k4, tbl_closed[k3][k4]);
+ v6.alg_enum = new_Il(i1+1, i2+1, i1+1, k3, i2+1, k4, back_closed, k3, j1, k4, j2);
+ /* No iteration neccessary! */
+ if (v6.alg_mfe < v7b.alg_mfe) {
+ free_str_Hybrid(v7b.alg_enum);
+ v7b = v6;
+ } else free_str_Hybrid(v6.alg_enum);
+ }
+ }
+ }
+ if (v7b.alg_mfe < 65000)
+ v7b.alg_mfe += il_stack_open(i1+1,i2+1);
+
+ v7c.alg_mfe = 65000;
+ v7c.alg_enum = NULL;
+ if ((x[k3]!=X)) { /* && !((k4 > helix_start) && (i2 < helix_end-1))) { */
+
+ for (k3=i1+4; k3<=min(i1+iloop_upper_limit+1, j1-1); k3++) {
+ if (x[k3]==X)
+ break;
+ for (k4=i2+2; k4<=min(i2+3, j2-1); k4++) {
+ if ((k4 > helix_start) && (i2 < helix_end-1))
+ break;
+ if (compl(x[k3+1],y[k4+1])) {
+ v6.alg_mfe = do_il(i1+1, i2+1, i1+1, k3, i2+1, k4, tbl_closed[k3][k4]);
+ v6.alg_enum = new_Il(i1+1, i2+1, i1+1, k3, i2+1, k4, back_closed, k3, j1, k4, j2);
+ /* No iteration neccessary! */
+ if (v6.alg_mfe < v7c.alg_mfe) {
+ free_str_Hybrid(v7c.alg_enum);
+ v7c = v6;
+ } else free_str_Hybrid(v6.alg_enum);
+ }
+ }
+ }
+ if (v7c.alg_mfe < 65000)
+ v7c.alg_mfe += il_stack_open(i1+1,i2+1);
+ }
+
+ v7d.alg_mfe = 65000;
+ v7d.alg_enum = NULL;
+ if ((x[k3]!=X)) { /* && !((k4 > helix_start) && (i2 < helix_end-1))) { */
+
+ /* normal internal loops: */
+ for (k3=i1+4; k3<=min(i1+iloop_upper_limit+1, j1-1); k3++) {
+ if (x[k3]==X)
+ break;
+ for (k4=i2+4; k4<=min(i2+iloop_upper_limit+1, j2-1); k4++) {
+ if ((k4 > helix_start) && (i2 < helix_end-1))
+ break;
+ if (compl(x[k3+1],y[k4+1])) {
+ v6.alg_mfe = do_il(i1+1, i2+1, i1+1, k3, i2+1, k4, tbl_closed[k3][k4]);
+ v6.alg_enum = new_Il(i1+1, i2+1, i1+1, k3, i2+1, k4, back_closed, k3, j1, k4, j2);
+ /* No iteration neccessary! */
+ if (v6.alg_mfe < v7d.alg_mfe) {
+ free_str_Hybrid(v7d.alg_enum);
+ v7d = v6;
+ } else free_str_Hybrid(v6.alg_enum);
+ }
+ }
+ }
+ if (v7d.alg_mfe < 65000)
+ v7d.alg_mfe += il_stack_open(i1+1,i2+1);
+
+ }
+
+ if (v7b.alg_mfe < v7c.alg_mfe) {
+ free_str_Hybrid(v7c.alg_enum);
+ v7e = v7b;
+ }
+ else {
+ free_str_Hybrid(v7b.alg_enum);
+ v7e = v7c;
+ }
+
+ if (v7e.alg_mfe < v7d.alg_mfe) {
+ free_str_Hybrid(v7d.alg_enum);
+ v7f = v7e;
+ }
+ else {
+ free_str_Hybrid(v7e.alg_enum);
+ v7f = v7d;
+ }
+
+ if (v7g.alg_mfe < v7f.alg_mfe) {
+ free_str_Hybrid(v7f.alg_enum);
+ }
+ else {
+ free_str_Hybrid(v7g.alg_enum);
+ v7g = v7f;
+ }
+ }
+ if (v7.alg_mfe < v7g.alg_mfe) {
+ free_str_Hybrid(v7g.alg_enum);
+ }
+ else {
+ free_str_Hybrid(v7.alg_enum);
+ v7 = v7g;
+ }
+ }
+ else {
+ v7.alg_mfe = 65000;
+ v7.alg_enum = NULL;
+ }
+ /* v7 = il <<< (tt(lbase, lbase) `with` (pairingTTcross compl)) ~~~ (tt(region, region) `with` (sizeTT 1 15 1 15)) ~~~ p closed */
+ /* ---------------------------------- finished --------------------------------- */
+
+ /* ---------------------------------- start of --------------------------------- */
+ /* v8 = el <<< (tt(lbase, lbase) `with` (pairingTTcross compl)) ~~~ (tt(uregion, uregion)) */
+ if (((j1-i1) >= 1) && ((j2-i2) >= 1) && (j1==i1+1 || x[i1+2]!='X') && ((i2 >= helix_end-1) || (helix_end > j2))) {
+ if (compl(x[i1+1], y[i2+1])) {
+ v8.alg_mfe = ((((j1) - (i1+1)) > 0) ? dli_energy(i1+1, i2+1) : 0) + ((((j2) - (i2+1)) > 0) ? dri_energy(i1+1, i2+1) : 0);
+ v8.alg_enum = new_El(i1+1, i2+1, i1+1, j1, i2+1, j2);
+ /* No iteration neccessary! */
+ }
+ else {
+ v8.alg_mfe = 65000;
+ v8.alg_enum = NULL;
+ }
+ }
+ else {
+ v8.alg_mfe = 65000;
+ v8.alg_enum = NULL;
+ }
+ /* v8 = el <<< (tt(lbase, lbase) `with` (pairingTTcross compl)) ~~~ (tt(uregion, uregion)) */
+ /* ---------------------------------- finished --------------------------------- */
+
+
+ /* ---------------------------- v9 = minimum(v7, v8) --------------------------- */
+ if (v7.alg_mfe < v8.alg_mfe) {
+ v9 = v7;
+ free_str_Hybrid(v8.alg_enum);
+ }
+ else {
+ v9 = v8;
+ free_str_Hybrid(v7.alg_enum);
+ }
+/* v9 = v7.alg_mfe < v8.alg_mfe ? v7 : v8; */
+
+ /* --------------------------- v10 = minimum(v5, v9) --------------------------- */
+ if (v5.alg_mfe < v9.alg_mfe) {
+ v10 = v5;
+ free_str_Hybrid(v9.alg_enum);
+ }
+ else {
+ v10 = v9;
+ free_str_Hybrid(v5.alg_enum);
+ }
+/* v10 = v5.alg_mfe < v9.alg_mfe ? v5 : v9; */
+
+ /* --------------------------- v11 = minimum(v3, v10) -------------------------- */
+ if (v3.alg_mfe < v10.alg_mfe) {
+ v11 = v3;
+ free_str_Hybrid(v10.alg_enum);
+ }
+ else {
+ v11 = v10;
+ free_str_Hybrid(v3.alg_enum);
+ }
+/* v11 = v3.alg_mfe < v10.alg_mfe ? v3 : v10; */
+
+ /* --------------------------- v12 = minimum(v1, v11) -------------------------- */
+ if (v1.alg_mfe < v11.alg_mfe) {
+ v12 = v1;
+ free_str_Hybrid(v11.alg_enum);
+ }
+ else {
+ v12 = v11;
+ free_str_Hybrid(v1.alg_enum);
+ }
+/* v12 = v1.alg_mfe < v11.alg_mfe ? v1 : v11; */
+
+ /* ------------------------- build candidate structures ------------------------ */
+
+ return(build_str_Hybrid(v12));
+}
+
+/* table memory allocation */
+/* -------------------------------------------------------------------------------- */
+
+void tableAlloc(int m, int n)
+{
+ int i, j, k, dim1, dim2;
+
+ /* --- memory allocation for tbl_unpaired_left_bot, yield size: ((1,m),(1,n)) -- */
+ dim1 = m-1;
+ tbl_unpaired_left_bot=(double **) calloc(dim1+1, sizeof(double *));
+ for (i=0; i<=dim1; i++) {
+ dim2 = n-1;
+ tbl_unpaired_left_bot[i]=(double *) calloc(dim2+1, sizeof(double));
+ }
+ /* -------- memory allocation for tbl_closed, yield size: ((1,m),(1,n)) -------- */
+ dim1 = m-1;
+ tbl_closed=(double **) calloc(dim1+1, sizeof(double *));
+ for (i=0; i<=dim1; i++) {
+ dim2 = n-1;
+ tbl_closed[i]=(double *) calloc(dim2+1, sizeof(double));
+ }
+ /* --- memory allocation for tbl_unpaired_left_top, yield size: ((1,m),(1,n)) -- */
+ dim1 = m-1;
+ tbl_unpaired_left_top=(double **) calloc(dim1+1, sizeof(double *));
+ for (i=0; i<=dim1; i++) {
+ dim2 = n-1;
+ tbl_unpaired_left_top[i]=(double *) calloc(dim2+1, sizeof(double));
+ }
+}
+
+/* main dynamic programming loop */
+/* -------------------------------------------------------------------------------- */
+
+
+void mainloop(int bflag, int hit_number, int eflag, float energy_cutoff, int pflag, float pvalue_cutoff, int compact_output, char *target_ac, char *target_sq, char *query_ac, char *query_sq, int gflag, int plot_format, float xi, float theta)
+{
+ int i1, i2;
+ double v2;
+ struct str1 l;
+
+ int
+ no_nil_so_far,
+ iterate,
+ hit_count,
+ k, k1, k2, sepPos,
+ ali_length,
+ hit_length,
+ t_len;
+
+ float
+ normalised_energy,
+ pvalue;
+
+ char hitcount_str[50];
+ char *filename;
+
+ char *conc_seq;
+ char *conc_struct;
+
+
+ no_nil_so_far = 1;
+ hit_count = 0;
+
+ for (iterate=1; iterate && (!bflag || hit_count<hit_number); ) {
+
+ for (i1=m; i1>=0; i1--) {
+ for (i2=n; i2>=0; i2--) {
+ calc_unpaired_left_bot(i1, m, i2, n);
+ calc_closed (i1, m, i2, n);
+ calc_unpaired_left_top(i1, m, i2, n);
+ }
+ }
+
+ /* ----------------------------- show axiom: hybrid ---------------------------- */
+ v2 = calc_hybrid(0, m, 0, n);
+
+
+ l = back_hybrid(0, m, 0, n);
+
+/* gx = 1; */
+
+ pp_str_Hybrid(l);
+
+ normalised_energy = v2/log(m*n);
+ pvalue = 1-exp(-exp(-(-normalised_energy-xi)/theta));
+
+ if ((!eflag || v2 <= energy_cutoff) && (!pflag || pvalue <= pvalue_cutoff) && no_nil_so_far) {
+
+ hit_count++;
+
+ if (compact_output) { /* compact output */
+ printf("%s:%d:%s:%d:%.1f:%.6f:%d:%s:%s:%s:%s\n",target_ac,m,query_ac,n,v2,pvalue,gx,t1,t2,t3,t4);
+ }
+ else { /* verbose output */
+ printf("target: %s\n", target_ac);
+ printf("length: %d\n", m);
+ printf("miRNA : %s\n", query_ac);
+ printf("length: %d\n", n);
+ printf("\n");
+ printf("mfe: %.1f kcal/mol\n", v2);
+ printf("p-value: %.6f\n", pvalue);
+ printf("\n");
+ printf("position %d\n", gx);
+ printf("target 5' %s 3'\n", t1);
+ printf(" %s \n", t2);
+ printf(" %s \n", t3);
+ printf("miRNA 3' %s 5'\n", t4);
+ printf("\n");
+ printf("\n");
+ }
+
+ if (gflag) { /* plot hybridisation */
+ ali_length = strlen(t1);
+
+ conc_seq = (char *) calloc(4 * ali_length +3 + 1,sizeof(char));
+ conc_struct = (char *) calloc(4 * ali_length +3 + 1,sizeof(char));
+
+ /* make dot-parantheses notation: */
+
+ k1 = 0;
+ for (k2=0; k2<ali_length; k2++) {
+ if (t1[k2]!=' ') {
+ conc_seq[k1]=t1[k2];
+ conc_struct[k1]='.';
+ k1++;
+ }
+ else if (t2[k2]!=' ') {
+ conc_seq[k1]=t2[k2];
+ conc_struct[k1]='(';
+ k1++;
+ }
+ }
+ conc_seq[k1]='N';
+ conc_seq[k1+1]='N';
+ conc_seq[k1+2]='N';
+ conc_struct[k1]='.';
+ conc_struct[k1+1]='.';
+ conc_struct[k1+2]='.';
+ k1+=3;
+ sepPos = k1;
+ for (k2=ali_length-1; k2>=0; k2--) {
+ if (t4[k2]!=' ') {
+ conc_seq[k1]=t4[k2];
+ conc_struct[k1]='.';
+ k1++;
+ }
+ else if (t3[k2]!=' ') {
+ conc_seq[k1]=t3[k2];
+ conc_struct[k1]=')';
+ k1++;
+ }
+ }
+
+ conc_seq[k1] = '\0';
+ conc_struct[k1] = '\0';
+
+/* printf("\n%s\n%s\n",conc_seq,conc_struct); */
+
+ sprintf(hitcount_str,"%d",hit_count);
+ filename = (char *) calloc(strlen(target_ac)+strlen(query_ac)+strlen(hitcount_str)+7, sizeof(char));
+
+ if (plot_format==PSPLOT || plot_format==ALLPLOT) {
+ strcpy(filename,target_ac);
+ strcat(filename,"_");
+ strcat(filename,query_ac);
+ strcat(filename,"_");
+ strcat(filename,hitcount_str);
+ strcat(filename,".ps");
+
+#ifdef HAVE_LIBG2
+ hybridPlot(conc_seq,conc_struct,v2,sepPos,filename,0,PSPLOT);
+#endif
+ }
+ if (plot_format==PNGPLOT || plot_format==ALLPLOT) {
+ strcpy(filename,target_ac);
+ strcat(filename,"_");
+ strcat(filename,query_ac);
+ strcat(filename,"_");
+ strcat(filename,hitcount_str);
+ strcat(filename,".png");
+
+#ifdef HAVE_LIBG2
+ hybridPlot(conc_seq,conc_struct,v2,sepPos,filename,0,PNGPLOT);
+#endif
+ }
+ if (plot_format==JPGPLOT || plot_format==ALLPLOT) {
+ strcpy(filename,target_ac);
+ strcat(filename,"_");
+ strcat(filename,query_ac);
+ strcat(filename,"_");
+ strcat(filename,hitcount_str);
+ strcat(filename,".jpg");
+
+#ifdef HAVE_LIBG2
+ hybridPlot(conc_seq,conc_struct,v2,sepPos,filename,0,JPGPLOT);
+#endif
+ }
+
+ free(filename);
+ free(conc_seq);
+ free(conc_struct);
+ }
+
+ t_len = strlen(t1);
+
+ if (t_len==0)
+ no_nil_so_far = 0;
+
+ k = 0;
+ while (k < t_len && t1[k]==' ' && t2[k]==' ')
+ k++;
+ if (k<t_len)
+ t1[k]=' '; /* hide left dangle */
+
+ k = t_len-1;
+ while (k >= 0 && t1[k]==' ' && t2[k]==' ')
+ k--;
+ if (k>=0)
+ t1[k]=' '; /* hide right dangle */
+
+ /* count hit length: */
+ hit_length = 0;
+
+ for (k=0; k<t_len; k++)
+ if (t1[k]!=' ')
+ hit_length++;
+
+ for (k=0; k<t_len; k++)
+ if (t2[k]!=' ')
+ hit_length++;
+
+/* printf("\n\nhitlength:%d\n\n",hit_length); */
+
+ /* mask hit: */
+ for (k=0; k<hit_length; k++)
+ x[gx+(t1[0]!=' ')+k]=X;
+
+/* for (k=1; k<=m; k++) */
+/* printf("%d",x[k]); */
+/* printf("\n\n"); */
+
+ if (!eflag && !bflag)
+ iterate = 0;
+
+ }
+ else
+ iterate = 0;
+
+
+ /* free candidate */
+ free_str_Hybrid(l.alg_enum);
+ /* initialize strings */
+ r1 = t1;
+ r2 = t2;
+ r3 = t3;
+ r4 = t4;
+ }
+}
+
+
+
Added: trunk/packages/rnahybrid/branches/upstream/current/src/hybrid_core.h
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/src/hybrid_core.h (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/src/hybrid_core.h 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,43 @@
+/* Copyright (C) 2004 Marc Rehmsmeier, Peter Steffen, Matthias Hoechsmann */
+
+/* This program is free software; you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation; either version 2 of the License, or (at your option) any later version. */
+
+/* This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details. */
+
+/* You should have received a copy of the GNU General Public License along with this program; if not, write to the Free Software Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA */
+
+#ifndef hybrid_core_h
+#define hybrid_core_h
+
+
+char *x; /* input string */
+int m; /* input length */
+char *y; /* input string */
+int n; /* input length */
+
+
+int iloop_upper_limit;
+int bloop_upper_limit;
+
+
+int helix_start, helix_end;
+
+
+int gx;
+char *t1, *t2, *t3, *t4;
+char *r1, *r2, *r3, *r4;
+
+int a1, a2, a3, a4, a5, a6;
+
+void calc_unpaired_left_top(int i1, int j1, int i2, int j2);
+
+void calc_unpaired_left_bot(int i1, int j1, int i2, int j2);
+
+void calc_closed(int i1, int j1, int i2, int j2);
+
+double calc_hybrid(int i1, int j1, int i2, int j2);
+
+void mainloop(int bflag, int hit_number, int eflag, float energy_cutoff, int pflag, float pvalue_cutoff, int compact_output, char *target_ac, char *target_sq, char *query_ac, char *query_sq, int gflag, int plot_format, float xi, float theta);
+
+
+#endif
Added: trunk/packages/rnahybrid/branches/upstream/current/src/input.c
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/src/input.c (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/src/input.c 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,56 @@
+/* Copyright (C) 2004 Marc Rehmsmeier, Peter Steffen, Matthias Hoechsmann */
+
+/* This program is free software; you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation; either version 2 of the License, or (at your option) any later version. */
+
+/* This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details. */
+
+/* You should have received a copy of the GNU General Public License along with this program; if not, write to the Free Software Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA */
+
+#include "input.h"
+#include <string.h>
+
+
+void convert_x(){
+ int i;
+ char c;
+ for (i=0; i<=m; i++) {
+ c=x[i];
+ if (c=='a' || c=='A') x[i]=A;
+ else if (c=='c' || c=='C') x[i]=C;
+ else if (c=='g' || c=='G') x[i]=G;
+ else if (c=='u' || c=='U') x[i]=U;
+ else if (c=='t' || c=='T') x[i]=U;
+ else x[i]=N;
+ }
+}
+
+void convert_y(){
+ int i;
+ char c;
+ for (i=0; i<=n; i++) {
+ c=y[i];
+ if (c=='a' || c=='A') y[i]=A;
+ else if (c=='c' || c=='C') y[i]=C;
+ else if (c=='g' || c=='G') y[i]=G;
+ else if (c=='u' || c=='U') y[i]=U;
+ else if (c=='t' || c=='T') y[i]=U;
+ else y[i]=N;
+ }
+}
+
+
+void remove_whitespace(char *sequence)
+{
+ int len = strlen(sequence);
+ int i;
+
+ for (i=0; i<len; i++)
+ if (sequence[i]<33) {
+ memmove(sequence+i,sequence+i+1,len-i-1);
+ len--;
+ i--;
+ }
+
+ sequence[len] = 0;
+}
+
Added: trunk/packages/rnahybrid/branches/upstream/current/src/input.h
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/src/input.h (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/src/input.h 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,38 @@
+/* Copyright (C) 2004 Marc Rehmsmeier, Peter Steffen, Matthias Hoechsmann */
+
+/* This program is free software; you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation; either version 2 of the License, or (at your option) any later version. */
+
+/* This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details. */
+
+/* You should have received a copy of the GNU General Public License along with this program; if not, write to the Free Software Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA */
+
+#ifndef input_h
+#define input_h
+
+
+extern char *x; /* input string */
+extern int m; /* input length */
+extern char *y; /* input string */
+extern int n; /* input length */
+
+
+#define A 0
+#define C 1
+#define G 2
+#define U 3
+#define N 4
+#define X 5 /* this is an additional letter for masking out hits */
+
+#define ALPHASIZE 5
+
+
+#define inpx(I) x[I]
+#define inpy(I) y[I]
+
+
+void convert_x();
+void convert_y();
+
+void remove_whitespace(char *sequence);
+
+#endif
Added: trunk/packages/rnahybrid/branches/upstream/current/src/minmax.h
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/src/minmax.h (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/src/minmax.h 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,15 @@
+/* Copyright (C) 2004 Marc Rehmsmeier, Peter Steffen, Matthias Hoechsmann */
+
+/* This program is free software; you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation; either version 2 of the License, or (at your option) any later version. */
+
+/* This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details. */
+
+/* You should have received a copy of the GNU General Public License along with this program; if not, write to the Free Software Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA */
+
+#ifndef minmax_h
+#define minmax_h
+
+#define min(A, B) ((A) < (B) ? (A) : (B))
+#define max(A, B) ((A) > (B) ? (A) : (B))
+
+#endif
Added: trunk/packages/rnahybrid/branches/upstream/current/src/mt19937-1.c
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/src/mt19937-1.c (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/src/mt19937-1.c 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,130 @@
+/* A C-program for MT19937: Real number version (1999/10/28) */
+/* genrand() generates one pseudorandom real number (double) */
+/* which is uniformly distributed on [0,1]-interval, for each */
+/* call. sgenrand(seed) sets initial values to the working area */
+/* of 624 words. Before genrand(), sgenrand(seed) must be */
+/* called once. (seed is any 32-bit integer.) */
+/* Integer generator is obtained by modifying two lines. */
+/* Coded by Takuji Nishimura, considering the suggestions by */
+/* Topher Cooper and Marc Rieffel in July-Aug. 1997. */
+
+/* This library is free software; you can redistribute it and/or */
+/* modify it under the terms of the GNU Library General Public */
+/* License as published by the Free Software Foundation; either */
+/* version 2 of the License, or (at your option) any later */
+/* version. */
+/* This library is distributed in the hope that it will be useful, */
+/* but WITHOUT ANY WARRANTY; without even the implied warranty of */
+/* MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. */
+/* See the GNU Library General Public License for more details. */
+/* You should have received a copy of the GNU Library General */
+/* Public License along with this library; if not, write to the */
+/* Free Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA */
+/* 02111-1307 USA */
+
+/* Copyright (C) 1997, 1999 Makoto Matsumoto and Takuji Nishimura. */
+/* Any feedback is very welcome. For any question, comments, */
+/* see http://www.math.keio.ac.jp/matumoto/emt.html or email */
+/* matumoto at math.keio.ac.jp */
+
+/* REFERENCE */
+/* M. Matsumoto and T. Nishimura, */
+/* "Mersenne Twister: A 623-Dimensionally Equidistributed Uniform */
+/* Pseudo-Random Number Generator", */
+/* ACM Transactions on Modeling and Computer Simulation, */
+/* Vol. 8, No. 1, January 1998, pp 3--30. */
+
+#include<stdio.h>
+
+/* Period parameters */
+#define N 624
+#define M 397
+#define MATRIX_A 0x9908b0df /* constant vector a */
+#define UPPER_MASK 0x80000000 /* most significant w-r bits */
+#define LOWER_MASK 0x7fffffff /* least significant r bits */
+
+/* Tempering parameters */
+#define TEMPERING_MASK_B 0x9d2c5680
+#define TEMPERING_MASK_C 0xefc60000
+#define TEMPERING_SHIFT_U(y) (y >> 11)
+#define TEMPERING_SHIFT_S(y) (y << 7)
+#define TEMPERING_SHIFT_T(y) (y << 15)
+#define TEMPERING_SHIFT_L(y) (y >> 18)
+
+static unsigned long mt[N]; /* the array for the state vector */
+static int mti=N+1; /* mti==N+1 means mt[N] is not initialized */
+
+/* Initializing the array with a seed */
+void
+sgenrand(seed)
+ unsigned long seed;
+{
+ int i;
+
+ for (i=0;i<N;i++) {
+ mt[i] = seed & 0xffff0000;
+ seed = 69069 * seed + 1;
+ mt[i] |= (seed & 0xffff0000) >> 16;
+ seed = 69069 * seed + 1;
+ }
+ mti = N;
+}
+
+/* Initialization by "sgenrand()" is an example. Theoretically, */
+/* there are 2^19937-1 possible states as an intial state. */
+/* This function allows to choose any of 2^19937-1 ones. */
+/* Essential bits in "seed_array[]" is following 19937 bits: */
+/* (seed_array[0]&UPPER_MASK), seed_array[1], ..., seed_array[N-1]. */
+/* (seed_array[0]&LOWER_MASK) is discarded. */
+/* Theoretically, */
+/* (seed_array[0]&UPPER_MASK), seed_array[1], ..., seed_array[N-1] */
+/* can take any values except all zeros. */
+void
+lsgenrand(seed_array)
+ unsigned long seed_array[];
+ /* the length of seed_array[] must be at least N */
+{
+ int i;
+
+ for (i=0;i<N;i++)
+ mt[i] = seed_array[i];
+ mti=N;
+}
+
+double /* generating reals */
+/* unsigned long */ /* for integer generation */
+genrand()
+{
+ unsigned long y;
+ static unsigned long mag01[2]={0x0, MATRIX_A};
+ /* mag01[x] = x * MATRIX_A for x=0,1 */
+
+ if (mti >= N) { /* generate N words at one time */
+ int kk;
+
+ if (mti == N+1) /* if sgenrand() has not been called, */
+ sgenrand(4357); /* a default initial seed is used */
+
+ for (kk=0;kk<N-M;kk++) {
+ y = (mt[kk]&UPPER_MASK)|(mt[kk+1]&LOWER_MASK);
+ mt[kk] = mt[kk+M] ^ (y >> 1) ^ mag01[y & 0x1];
+ }
+ for (;kk<N-1;kk++) {
+ y = (mt[kk]&UPPER_MASK)|(mt[kk+1]&LOWER_MASK);
+ mt[kk] = mt[kk+(M-N)] ^ (y >> 1) ^ mag01[y & 0x1];
+ }
+ y = (mt[N-1]&UPPER_MASK)|(mt[0]&LOWER_MASK);
+ mt[N-1] = mt[M-1] ^ (y >> 1) ^ mag01[y & 0x1];
+
+ mti = 0;
+ }
+
+ y = mt[mti++];
+ y ^= TEMPERING_SHIFT_U(y);
+ y ^= TEMPERING_SHIFT_S(y) & TEMPERING_MASK_B;
+ y ^= TEMPERING_SHIFT_T(y) & TEMPERING_MASK_C;
+ y ^= TEMPERING_SHIFT_L(y);
+
+ return ( (double)y * 2.3283064370807974e-10 ); /* reals */
+ /* return y; */ /* for integer generation */
+}
Added: trunk/packages/rnahybrid/branches/upstream/current/src/mt19937-1.h
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/src/mt19937-1.h (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/src/mt19937-1.h 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,12 @@
+#ifdef __cplusplus
+extern "C" {
+#endif
+
+void sgenrand(unsigned long seed);
+
+double genrand();
+
+
+#ifdef __cplusplus
+}
+#endif
Added: trunk/packages/rnahybrid/branches/upstream/current/src/numerical.c
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/src/numerical.c (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/src/numerical.c 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,298 @@
+/* Copyright (C) 2004 Marc Rehmsmeier, Peter Steffen, Matthias Hoechsmann */
+
+/* This program is free software; you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation; either version 2 of the License, or (at your option) any later version. */
+
+/* This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details. */
+
+/* You should have received a copy of the GNU General Public License along with this program; if not, write to the Free Software Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA */
+
+#include "globals.h"
+#include "minmax.h"
+#include "math.h"
+
+
+int compare_floats (const void *a, const void *b)
+{
+ const float *da = (const float *) a;
+ const float *db = (const float *) b;
+
+ return (*da > *db) - (*da < *db);
+}
+
+
+void empirical_cumulative_distribution_function(float **xcdf, float **ycdf, float *bin_number, float *xs, int sample_size)
+{
+ float min_e;
+ float max_e;
+
+ float bin_width, bin;
+
+ int k, i;
+
+ qsort(xs,sample_size,sizeof(float),compare_floats);
+
+ (*bin_number) = min(sample_size,BINNUMBER);
+
+ *xcdf = (float *) calloc(BINNUMBER,sizeof(float));
+ *ycdf = (float *) calloc(BINNUMBER+1,sizeof(float));
+
+
+ min_e = 0.0;
+ max_e = xs[sample_size-1];
+
+ bin_width = fabs(max_e - min_e) / ((float) (*bin_number));
+
+ k = 0;
+ (*ycdf)[0] = 0.0;
+
+ bin = 0.0;
+
+ i = 0;
+
+ for (k=1; k<=(*bin_number); k++) {
+ bin = bin + bin_width;
+ (*xcdf)[k-1] = bin;
+ (*ycdf)[k] = (*ycdf)[k-1];
+ while (i<sample_size && xs[i] <= bin) {
+ (*ycdf)[k]++;
+ i++;
+ }
+ }
+
+ for (k=1;k<=(*bin_number);k++)
+ (*ycdf)[k] /= sample_size;
+}
+
+
+float mean(float *xs, int sample_size)
+{
+ float sum = 0.0;
+
+ int k;
+ for (k=0; k<sample_size; k++)
+ sum += xs[k];
+
+ return (sum/sample_size);
+}
+
+
+
+float variance(float *xs, int sample_size)
+{
+ float m = mean(xs,sample_size);
+
+ float sum = 0.0;
+ int k;
+ for (k=0; k<sample_size; k++)
+ sum += pow(m-xs[k],2);
+
+ return (sum / (sample_size-1));
+}
+
+void linear_regression(float *slope, float *intercept, float *xs, float *ys, int sample_size)
+{
+ float var, s, sx, sy, sxx, sxy, delta;
+ int k;
+
+ var = variance(ys,sample_size);
+ s = 0.0;
+ for (k=0; k<sample_size; k++)
+ s += 1.0/var;
+ sx = 0.0;
+ for (k=0; k<sample_size; k++)
+ sx += xs[k]/var;
+ sy = 0.0;
+ for (k=0; k<sample_size; k++)
+ sy += ys[k]/var;
+ sxx = 0.0;
+ for (k=0; k<sample_size; k++)
+ sxx += xs[k]*xs[k]/var;
+ sxy = 0.0;
+ for (k=0; k<sample_size; k++)
+ sxy += xs[k]*ys[k]/var;
+ delta = s*sxx-sx*sx;
+ (*slope) = (s*sxy-sx*sy)/delta;
+ (*intercept) = (sxx*sy-sx*sxy)/delta;
+}
+
+
+void estimate_evd_parameters(int *used_sample_size, float *xi, float *theta, float *normalised_energies, int sample_size)
+{
+ float *xcdf, *ycdf;
+ float bin_number;
+ int start, end;
+
+ /* calculate empirical cdf: */
+ empirical_cumulative_distribution_function(&xcdf,&ycdf,&bin_number,normalised_energies,sample_size);
+
+ /* delete values below normalised energy of FITLOWERCUTOFFABSOLUTE: */
+ start=0;
+
+ while (start<bin_number && xcdf[start] < FITLOWERCUTOFFABSOLUTE)
+ start++;
+
+ /* delete top FITUPPERCUTOFFPERCENT values: */
+ end = (int) bin_number * (100.0 - FITUPPERCUTOFFPERCENT) / 100.0 - 1;
+
+ (*used_sample_size) = end-start+1;
+
+ if (end<=start) {
+ (*xi) = 0.0;
+ (*theta) = 0.0;
+ }
+ else {
+ /* do linear regression on log(-log) transformed cdf: */
+ float slope, intercept;
+ int k;
+ for (k=start; k<=end; k++)
+ ycdf[k+1] = log(-log(ycdf[k+1]));
+
+ linear_regression(&slope,&intercept,xcdf+start,ycdf+start+1,end-start+1);
+
+ (*theta) = -1.0/slope;
+ (*xi) = intercept * (*theta);
+ }
+
+ free(xcdf);
+ free(ycdf);
+}
+
+
+#define GOLD 1.618034
+#define GLIMIT 100.0
+#define TINY 1.0e-20
+#define MAX(a,b) ((a) > (b) ? (a) : (b))
+#define SIGN(a,b) ((b) > 0.0 ? fabs(a) : -fabs(a))
+#define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d);
+
+void mnbrak(float *ax, float *bx, float *cx, float *fa, float *fb, float *fc, float (*func)(float))
+{
+ float ulim,u,r,q,fu,dum;
+
+ *fa=(*func)(*ax);
+ *fb=(*func)(*bx);
+ if (*fb > *fa) {
+ SHFT(dum,*ax,*bx,dum)
+ SHFT(dum,*fb,*fa,dum)
+ }
+ *cx=(*bx)+GOLD*(*bx-*ax);
+ *fc=(*func)(*cx);
+ while (*fb > *fc) {
+ r=(*bx-*ax)*(*fb-*fc);
+ q=(*bx-*cx)*(*fb-*fa);
+ u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/
+ (2.0*SIGN(MAX(fabs(q-r),TINY),q-r));
+ ulim=(*bx)+GLIMIT*(*cx-*bx);
+ if ((*bx-u)*(u-*cx) > 0.0) {
+ fu=(*func)(u);
+ if (fu < *fc) {
+ *ax=(*bx);
+ *bx=u;
+ *fa=(*fb);
+ *fb=fu;
+ return;
+ } else if (fu > *fb) {
+ *cx=u;
+ *fc=fu;
+ return;
+ }
+ u=(*cx)+GOLD*(*cx-*bx);
+ fu=(*func)(u);
+ } else if ((*cx-u)*(u-ulim) > 0.0) {
+ fu=(*func)(u);
+ if (fu < *fc) {
+ SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx))
+ SHFT(*fb,*fc,fu,(*func)(u))
+ }
+ } else if ((u-ulim)*(ulim-*cx) >= 0.0) {
+ u=ulim;
+ fu=(*func)(u);
+ } else {
+ u=(*cx)+GOLD*(*cx-*bx);
+ fu=(*func)(u);
+ }
+ SHFT(*ax,*bx,*cx,u)
+ SHFT(*fa,*fb,*fc,fu)
+ }
+}
+
+#undef GOLD
+#undef GLIMIT
+#undef TINY
+#undef MAX
+#undef SIGN
+#undef SHFT
+
+
+#define ITMAX 100
+#define CGOLD 0.3819660
+#define ZEPS 1.0e-10
+#define SIGN(a,b) ((b) > 0.0 ? fabs(a) : -fabs(a))
+#define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d);
+
+float brent(float ax, float bx, float cx, float (*f)(float), float tol, float *xmin)
+{
+ int iter;
+ float a,b,d,etemp,fu,fv,fw,fx,p,q,r,tol1,tol2,u,v,w,x,xm;
+ float e=0.0;
+
+ a=((ax < cx) ? ax : cx);
+ b=((ax > cx) ? ax : cx);
+ x=w=v=bx;
+ fw=fv=fx=(*f)(x);
+ for (iter=1;iter<=ITMAX;iter++) {
+ xm=0.5*(a+b);
+ tol2=2.0*(tol1=tol*fabs(x)+ZEPS);
+ if (fabs(x-xm) <= (tol2-0.5*(b-a))) {
+ *xmin=x;
+ return fx;
+ }
+ if (fabs(e) > tol1) {
+ r=(x-w)*(fx-fv);
+ q=(x-v)*(fx-fw);
+ p=(x-v)*q-(x-w)*r;
+ q=2.0*(q-r);
+ if (q > 0.0) p = -p;
+ q=fabs(q);
+ etemp=e;
+ e=d;
+ if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x))
+ d=CGOLD*(e=(x >= xm ? a-x : b-x));
+ else {
+ d=p/q;
+ u=x+d;
+ if (u-a < tol2 || b-u < tol2)
+ d=SIGN(tol1,xm-x);
+ }
+ } else {
+ d=CGOLD*(e=(x >= xm ? a-x : b-x));
+ }
+ u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d));
+ fu=(*f)(u);
+ if (fu <= fx) {
+ if (u >= x) a=x; else b=x;
+ SHFT(v,w,x,u)
+ SHFT(fv,fw,fx,fu)
+ } else {
+ if (u < x) a=u; else b=u;
+ if (fu <= fw || w == x) {
+ v=w;
+ w=u;
+ fv=fw;
+ fw=fu;
+ } else if (fu <= fv || v == x || v == w) {
+ v=u;
+ fv=fu;
+ }
+ }
+ }
+ printf("Too many iterations in BRENT\n");
+ *xmin=x;
+ return fx;
+}
+
+#undef ITMAX
+#undef CGOLD
+#undef ZEPS
+#undef SIGN
+
Added: trunk/packages/rnahybrid/branches/upstream/current/src/numerical.h
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/src/numerical.h (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/src/numerical.h 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,29 @@
+/* Copyright (C) 2004 Marc Rehmsmeier, Peter Steffen, Matthias Hoechsmann */
+
+/* This program is free software; you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation; either version 2 of the License, or (at your option) any later version. */
+
+/* This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details. */
+
+/* You should have received a copy of the GNU General Public License along with this program; if not, write to the Free Software Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA */
+
+#ifndef numerical_h
+#define numerical_h
+
+
+int compare_floats (const void *a, const void *b);
+
+void empirical_cumulative_distribution_function(float **xcdf, float **ycdf, float *bin_number, float *xs, int sample_size);
+
+float mean(float *xs, int sample_size);
+
+float variance(float *xs, int sample_size);
+
+void linear_regression(float *slope, float *intercept, float *xs, float *ys, int sample_size);
+
+void estimate_evd_parameters(int *used_sample_size, float *xi, float *theta, float *normalised_energies, int sample_size);
+
+void mnbrak(float *ax, float *bx, float *cx, float *fa, float *fb, float *fc, float (*func)(float));
+
+float brent(float ax, float bx, float cx, float (*)(float), float tol, float *xmin);
+
+#endif
Added: trunk/packages/rnahybrid/branches/upstream/current/src/plot.c
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/src/plot.c (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/src/plot.c 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,424 @@
+/* Copyright (C) 2004 Marc Rehmsmeier, Peter Steffen, Matthias Hoechsmann */
+
+/* This program is free software; you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation; either version 2 of the License, or (at your option) any later version. */
+
+/* This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details. */
+
+/* You should have received a copy of the GNU General Public License along with this program; if not, write to the Free Software Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA */
+
+#include "config.h"
+#include "plot.h"
+
+#ifdef HAVE_LIBG2
+
+#ifdef HAVE_LIBGD
+#include <g2_gd.h>
+#endif
+
+void loop(int i, int j, short *pair_table);
+
+short *make_pair_table(const char *structure);
+
+void *space(unsigned size);
+
+void nrerror(const char message[]);
+
+/* local variables for parsing routines */
+
+float *angle;
+int *loop_size, *stack_size;
+int lp, stk;
+
+#ifndef PI
+#define PI 3.141592654
+#endif
+#define PIHALF PI/2.
+
+
+
+void hybridPlot(char *seq, char *str, double energy, int sepPos, char *filename, int blackWhite, int format)
+{
+ double base_fontsize=12;
+ float *X, *Y,min_X=0,max_X=0,min_Y=0,max_Y=0;
+ unsigned int i;
+ short *pair_table;
+ int id_PS,id;
+ int ps_color_black,ps_color_red,ps_color_blue;
+ char energy_str[50];
+
+#ifdef HAVE_LIBGD
+ int id_PNG=0,id_JPG=0;
+ int png_color_black,png_color_red,png_color_blue;
+ int jpg_color_black,jpg_color_red,jpg_color_blue;
+#endif
+
+ unsigned int basenr_x=0, basenr_y=0;
+ double xpos,ypos;
+ char buf[2];
+
+ buf[1]=0;
+
+ // assert(strlen(str) == strlen(seq));
+
+ X = (float *) calloc(strlen(seq)+1,sizeof(float));
+ Y = (float *) calloc(strlen(seq)+1,sizeof(float));
+
+ pair_table = make_pair_table(str);
+ i = simple_xy_coordinates(pair_table, X, Y);
+ if(i!=strlen(str))
+ printf("strange things happening in squigglePlot ...");
+
+ // scale image
+ // for(i=0;i<strlen(str);i++)
+ // {
+ // X[i]*=options.scale;
+ // Y[i]*=options.scale;
+ // }
+
+ // calculate image dimensions
+ for(i=0;i<strlen(str);i++)
+ {
+ min_X=min(min_X,X[i]);
+ max_X=max(max_X,X[i]);
+ min_Y=min(min_Y,Y[i]);
+ max_Y=max(max_Y,Y[i]);
+ }
+
+ // add a border to image size
+ min_X-=10;
+ max_X+=10;
+ min_Y-=10;
+ max_Y+=10;
+
+ // open device with respect to "format"
+ id = g2_open_vd();
+
+ if(format==PSPLOT)
+ {
+ id_PS = g2_open_EPSF(filename);
+ g2_attach(id,id_PS);
+ }
+
+#ifdef HAVE_LIBGD
+ if(format==PNGPLOT)
+ {
+ id_PNG=g2_open_gd(filename,(int)(max_X-min_X),(int)(max_Y-min_Y),g2_gd_png);
+ g2_attach(id,id_PNG);
+ }
+ if(format==JPGPLOT)
+ {
+ id_JPG=g2_open_gd(filename,(int)(max_X-min_X),(int)(max_Y-min_Y),g2_gd_jpeg);
+ g2_attach(id,id_JPG);
+ }
+#endif
+
+ g2_set_coordinate_system(id,-min_X,-min_Y,1,1);
+
+ // drawing parameters
+ g2_set_line_width(id,0.6);
+
+ // mark 5' end
+ g2_string(id,X[0]-20,Y[0],"5'");
+
+ // print energy:
+ sprintf(energy_str,"mfe: %.1f kcal/mol",energy);
+ g2_string(id,min_X+40,min_Y+20,energy_str);
+
+ // define colors
+ if(blackWhite)
+ {
+ switch(format)
+ {
+ case PSPLOT:
+ ps_color_black=g2_ink(id_PS,0,0,0);
+ ps_color_red=g2_ink(id_PS,0,0,0);
+ ps_color_blue=g2_ink(id_PS,0,0,0);
+ break;
+#ifdef HAVE_LIBGD
+ case PNGPLOT:
+ png_color_black=g2_ink(id_PNG,0,0,0);
+ png_color_red=g2_ink(id_PNG,0,0,0);
+ png_color_blue=g2_ink(id_PNG,0,0,0);
+
+ ps_color_black=png_color_black;
+ ps_color_red=png_color_red;
+ ps_color_blue=png_color_blue;
+
+ break;
+ case JPGPLOT:
+ jpg_color_black=g2_ink(id_JPG,0,0,0);
+ jpg_color_red=g2_ink(id_JPG,0,0,0);
+ jpg_color_blue=g2_ink(id_JPG,0,0,0);
+
+ ps_color_black=jpg_color_black;
+ ps_color_red=jpg_color_red;
+ ps_color_blue=jpg_color_blue;
+
+ break;
+#endif
+ }
+ }
+ else
+ {
+ switch(format)
+ {
+ case PSPLOT:
+ ps_color_black=g2_ink(id_PS,0,0,0);
+ ps_color_red=g2_ink(id_PS,1,0,0);
+ ps_color_blue=g2_ink(id_PS,0,0.75,0);
+ break;
+#ifdef HAVE_LIBGD
+ case PNGPLOT:
+ png_color_black=g2_ink(id_PNG,0,0,0);
+ png_color_red=g2_ink(id_PNG,1,0,0);
+ png_color_blue=g2_ink(id_PNG,0,0.75,0);
+
+ ps_color_black=png_color_black;
+ ps_color_red=png_color_red;
+ ps_color_blue=png_color_blue;
+
+ break;
+ case JPGPLOT:
+ jpg_color_black=g2_ink(id_JPG,0,0,0);
+ jpg_color_red=g2_ink(id_JPG,1,0,0);
+ jpg_color_blue=g2_ink(id_JPG,0,0.75,0);
+
+ ps_color_black=jpg_color_black;
+ ps_color_red=jpg_color_red;
+ ps_color_blue=jpg_color_blue;
+
+ break;
+#endif
+ }
+ }
+
+ // draw sequence
+ g2_set_font_size(id,base_fontsize);
+ for(i=0;i<strlen(str);i++)
+ {
+ if(i<sepPos)
+ g2_pen(id,ps_color_red);
+ else
+ g2_pen(id,ps_color_blue);
+
+ buf[0]=seq[i];
+ xpos=X[i]-base_fontsize/2;
+ ypos=Y[i]-4;
+ if (i<=sepPos-4 || i > sepPos-1)
+ g2_string(id,xpos,ypos,buf);
+
+ // connection to next base
+ if(i<strlen(str)-1)
+ {
+ if(i<sepPos-4 || i>sepPos-1)
+ {
+ if(i<sepPos)
+ g2_pen(id,ps_color_red);
+ else
+ g2_pen(id,ps_color_blue);
+ g2_line(id,X[i],Y[i],X[i+1],Y[i+1]);
+ }
+
+ // draw circles at line endpoints
+/* if(i<sepPos) */
+/* g2_pen(id,ps_color_red); */
+/* else */
+/* g2_pen(id,ps_color_blue); */
+/* g2_filled_circle(id,X[i],Y[i],0.7); // circles are drawn twice, but thats ok ... */
+ }
+ }
+
+ // draw pairings
+ // !!! pair_table indexing begins at 1 !!!
+ for(i=0;i<strlen(str);i++)
+ {
+ if((unsigned short)pair_table[i+1]>i+1)
+ {
+ // pairs in both structures
+ g2_pen(id,ps_color_black);
+ g2_pen(id,ps_color_black);
+ g2_line(id,X[i],Y[i],X[pair_table[i+1]-1],Y[pair_table[i+1]-1]);
+ }
+ }
+
+
+ g2_flush(id);
+ g2_close(id);
+
+ free(pair_table);
+ free(X);
+ free(Y);
+}
+
+
+
+short *make_pair_table(const char *structure)
+{
+ /* returns array representation of structure.
+ table[i] is 0 if unpaired or j if (i.j) pair. */
+ short i,j,hx;
+ short length;
+ short *stack;
+ short *table;
+
+ length = (short) strlen(structure);
+ stack = (short *) space(sizeof(short)*(length+1));
+ table = (short *) space(sizeof(short)*(length+2));
+ table[0] = length;
+
+ for (hx=0, i=1; i<=length; i++) {
+ switch (structure[i-1]) {
+ case '(':
+ stack[hx++]=i;
+ break;
+ case ')':
+ j = stack[--hx];
+ if (hx<0) {
+ fprintf(stderr, "%s\n", structure);
+ nrerror("unbalanced brackets in make_pair_table");
+ }
+ table[i]=j;
+ table[j]=i;
+ break;
+ default: /* unpaired base, usually '.' */
+ table[i]= 0;
+ break;
+ }
+ }
+ if (hx!=0) {
+ fprintf(stderr, "%s\n", structure);
+ nrerror("unbalanced brackets in make_pair_table");
+ }
+ free(stack);
+ return(table);
+}
+
+
+void *space(unsigned size)
+{
+ void *pointer;
+
+ if ( (pointer = (void *) calloc(1, (size_t) size)) == NULL) {
+ nrerror("SPACE allocation failure -> no memory");
+ }
+ return pointer;
+}
+
+
+void nrerror(const char message[]) /* output message upon error */
+{
+ fprintf(stderr, "\n%s\n", message);
+ exit(2);
+}
+
+
+int simple_xy_coordinates(short *pair_table, float *x, float *y)
+{
+ float INIT_ANGLE=0.; /* initial bending angle */
+ float INIT_X = 100.; /* coordinate of first digit */
+ float INIT_Y = 100.; /* see above */
+ float RADIUS = 15.;
+
+ int i, length;
+ float alpha;
+
+ length = pair_table[0];
+ angle = (float*) space( (length+5)*sizeof(float) );
+ loop_size = (int*) space( 16+(length/5)*sizeof(int) );
+ stack_size = (int*) space( 16+(length/5)*sizeof(int) );
+ lp = stk = 0;
+ loop(0, length+1, pair_table);
+ loop_size[lp] -= 2; /* correct for cheating with function loop */
+
+ alpha = INIT_ANGLE;
+ x[0] = INIT_X;
+ y[0] = INIT_Y;
+
+ for (i = 1; i <= length; i++) {
+ x[i] = x[i-1]+RADIUS*cos(alpha);
+ y[i] = y[i-1]+RADIUS*sin(alpha);
+ alpha += PI-angle[i+1];
+ }
+ free(angle);
+ free(loop_size);
+ free(stack_size);
+
+ return length;
+
+}
+
+/*---------------------------------------------------------------------------*/
+
+void loop(int i, int j, short *pair_table)
+ /* i, j are the positions AFTER the last pair of a stack; i.e
+ i-1 and j+1 are paired. */
+{
+ int count = 2; /* counts the VERTICES of a loop polygon; that's
+ NOT necessarily the number of unpaired bases!
+ Upon entry the loop has already 2 vertices, namely
+ the pair i-1/j+1. */
+
+ int r = 0, bubble = 0; /* bubble counts the unpaired digits in loops */
+
+ int i_old, partner, k, l, start_k, start_l, fill, ladder;
+ int begin, v, diff;
+ float polygon;
+
+ short *remember;
+
+ remember = (short *) space((1+(j-i)/5)*2*sizeof(short));
+
+ i_old = i-1, j++; /* j has now been set to the partner of the
+ previous pair for correct while-loop
+ termination. */
+ while (i != j) {
+ partner = pair_table[i];
+ if ((!partner) || (i==0))
+ i++, count++, bubble++;
+ else {
+ count += 2;
+ k = i, l = partner; /* beginning of stack */
+ remember[++r] = k;
+ remember[++r] = l;
+ i = partner+1; /* next i for the current loop */
+
+ start_k = k, start_l = l;
+ ladder = 0;
+ do {
+ k++, l--, ladder++; /* go along the stack region */
+ }
+ while (pair_table[k] == l);
+
+ fill = ladder-2;
+ if (ladder >= 2) {
+ angle[start_k+1+fill] += PIHALF; /* Loop entries and */
+ angle[start_l-1-fill] += PIHALF; /* exits get an */
+ angle[start_k] += PIHALF; /* additional PI/2. */
+ angle[start_l] += PIHALF; /* Why ? (exercise) */
+ if (ladder > 2) {
+ for (; fill >= 1; fill--) {
+ angle[start_k+fill] = PI; /* fill in the angles */
+ angle[start_l-fill] = PI; /* for the backbone */
+ }
+ }
+ }
+ stack_size[++stk] = ladder;
+ loop(k, l, pair_table);
+ }
+ }
+ polygon = PI*(count-2)/(float)count; /* bending angle in loop polygon */
+ remember[++r] = j;
+ begin = i_old < 0 ? 0 : i_old;
+ for (v = 1; v <= r; v++) {
+ diff = remember[v]-begin;
+ for (fill = 0; fill <= diff; fill++)
+ angle[begin+fill] += polygon;
+ if (v > r)
+ break;
+ begin = remember[++v];
+ }
+ loop_size[++lp] = bubble;
+ free(remember);
+}
+
+#endif
Added: trunk/packages/rnahybrid/branches/upstream/current/src/plot.h
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/src/plot.h (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/src/plot.h 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,35 @@
+/* Copyright (C) 2004 Marc Rehmsmeier, Peter Steffen, Matthias Hoechsmann */
+
+/* This program is free software; you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation; either version 2 of the License, or (at your option) any later version. */
+
+/* This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details. */
+
+/* You should have received a copy of the GNU General Public License along with this program; if not, write to the Free Software Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA */
+
+#ifndef plot_h
+#define plot_h
+
+#include "config.h"
+
+#define PSPLOT 0
+#define PNGPLOT 1
+#define JPGPLOT 2
+#define ALLPLOT 3
+
+
+
+#ifdef HAVE_LIBG2
+
+#include <stdio.h>
+#include <g2.h>
+#include <g2_PS.h>
+#include "minmax.h"
+
+
+
+void hybridPlot(char *seq, char *str, double energy, int sepPos, char *filename, int blackWhite, int format);
+
+
+#endif
+
+#endif
Added: trunk/packages/rnahybrid/branches/upstream/current/src/random.c
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/src/random.c (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/src/random.c 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,112 @@
+/* Copyright (C) 2004 Marc Rehmsmeier, Peter Steffen, Matthias Hoechsmann */
+
+/* This program is free software; you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation; either version 2 of the License, or (at your option) any later version. */
+
+/* This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details. */
+
+/* You should have received a copy of the GNU General Public License along with this program; if not, write to the Free Software Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA */
+
+#include "random.h"
+#include "globals.h"
+#include "mt19937-1.h"
+#include <sys/types.h>
+#include <stdio.h>
+#include <string.h>
+#include <math.h>
+
+
+
+char *alphabet = "ACGT";
+
+
+void read_dinucleotide_frequencies(float **freq_di, FILE *f)
+{
+ char s [MAXLINE];
+ int i,j;
+
+ while (fgets(s,MAXLINE,f)!=NULL) {
+ if (s[0] != '#') {
+ switch (toupper(s[0])) {
+ case 'A':
+ i=0;
+ break;
+ case 'C':
+ i=1;
+ break;
+ case 'G':
+ i=2;
+ break;
+ case 'T':
+ i=3;
+ break;
+ case 'U':
+ i=3;
+ break;
+ }
+ switch (toupper(s[1])) {
+ case 'A':
+ j=0;
+ break;
+ case 'C':
+ j=1;
+ break;
+ case 'G':
+ j=2;
+ break;
+ case 'T':
+ j=3;
+ break;
+ case 'U':
+ j=3;
+ break;
+ }
+ sscanf(s,"%*s %f",&(freq_di[i][j]));
+ }
+ }
+}
+
+
+char* random_sequence(int seqlen, float *fdf, float **fdf_di)
+{
+ int i, c;
+ float s;
+
+ char *sequence = (char *) calloc(seqlen+1,sizeof(char));
+
+ for (i=0; i<seqlen; i++) {
+ s = genrand();
+ c = 0;
+ if (i==0) {
+ while (fdf[c]<s) c++;
+ }
+ else {
+ while (fdf_di[strchr(alphabet,sequence[i-1])-alphabet][c]<s) c++;
+ }
+ sequence[i]=alphabet[c];
+ }
+ sequence[seqlen] = '\0';
+
+ return sequence;
+}
+
+
+float normal_random_number()
+{
+ float u1, u2, v1,v2,s,z;
+
+ do {
+
+ u1 = genrand();
+ u2 = genrand();
+
+ v1 = 2*u1-1;
+ v2 = 2*u2-1;
+
+ s = pow(v1,2) + pow(v2,2);
+
+ } while (s > 1);
+
+ z = sqrt(-2*log(s)/s)*v1;
+
+ return z;
+}
Added: trunk/packages/rnahybrid/branches/upstream/current/src/random.h
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/src/random.h (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/src/random.h 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,33 @@
+/* Copyright (C) 2004 Marc Rehmsmeier, Peter Steffen, Matthias Hoechsmann */
+
+/* This program is free software; you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation; either version 2 of the License, or (at your option) any later version. */
+
+/* This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details. */
+
+/* You should have received a copy of the GNU General Public License along with this program; if not, write to the Free Software Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA */
+
+/* Copyright (C) 2004 Marc Rehmsmeier, Peter Steffen, Matthias Hoechsmann */
+
+/* This program is free software; you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation; either version 2 of the License, or (at your option) any later version. */
+
+/* This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details. */
+
+/* You should have received a copy of the GNU General Public License along with this program; if not, write to the Free Software Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA */
+
+#ifndef random_h
+#define random_h
+
+#include <stdio.h>
+
+
+extern char *alphabet;
+
+
+void read_dinucleotide_frequencies(float **freq_di, FILE *f);
+
+char *random_sequence(int seqlen, float *fdf, float **fdf_di);
+
+float normal_random_number();
+
+
+#endif
Added: trunk/packages/rnahybrid/branches/upstream/current/src/rnacalibrate.c
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/src/rnacalibrate.c (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/src/rnacalibrate.c 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,705 @@
+/* Copyright (C) 2004 Marc Rehmsmeier, Peter Steffen, Matthias Hoechsmann */
+
+/* This program is free software; you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation; either version 2 of the License, or (at your option) any later version. */
+
+/* This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details. */
+
+/* You should have received a copy of the GNU General Public License along with this program; if not, write to the Free Software Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA */
+
+#include "hybrid_core.h"
+#include "numerical.h"
+#include "random.h"
+#include "globals.h"
+#include "minmax.h"
+#include "mt19937-1.h"
+#include <stdio.h>
+#include <sys/types.h>
+#include <time.h>
+#include <math.h>
+#include <stdlib.h>
+
+
+static char const rcsid[] = "$Id: rnacalibrate.c,v 1.11 2004/11/16 15:42:33 marc Exp $";
+
+
+struct output {
+ char query_ac[MAXLINE];
+ int used_sample_size;
+ float location, scale;
+};
+
+
+int main(int argc, char **argv)
+{
+ extern char *optarg;
+ extern int optind;
+ int c;
+ int
+ dflag = 0, // file with dinucleotide parameters
+ fflag = 0, // force helix, arguments: from,to (positions in miRNA)
+ hflag = 0, // help
+ kflag = 0, // number of sequences to generate
+ lflag = 0, // length distribution parameters (mean, std deviation)
+ mflag = 0, // max target length
+ nflag = 0, // max query length
+ qflag = 0, // query input file
+ sflag = 0, // make random sequences according to target file
+ tflag = 0, // target input file
+ uflag = 0, // upper size for internal loops (per side)
+ vflag = 0, // upper size for bulge loops
+ errflag = 0;
+
+ int
+ maxtargetlength,
+ maxquerylength;
+ char
+ *query_fn, // query filename
+ *target_fn;
+
+ char target_ac[MAXLINE];
+ char query_ac[MAXLINE];
+
+ char *target_sq;
+ char *query_sq;
+
+ char *freq_filename;
+
+ int i1, i2;
+ double v2, normalised_energy;
+
+ int
+ fflag_start,
+ fflag_end;
+ int
+ targetlength,
+ querylength;
+
+ int mean, stddev, sample_size;
+
+ struct output output;
+
+ FILE *f;
+
+ int i,j,k,seqlen;
+
+ char letter_one, letter_two;
+
+ int index_one, index_two;
+
+ int counter;
+
+
+
+ float *normalised_energies;
+
+ float **freq_di = (float **) calloc(4,sizeof(float*));
+ float **fdf_di = (float **) calloc(4,sizeof(float*));
+ float *freq;
+ float *fdf;
+
+ for (i=0; i<4; i++) {
+ freq_di[i] = (float *) calloc(4,sizeof(float));
+ fdf_di[i] = (float *) calloc(4,sizeof(float));
+ }
+ freq = (float *) calloc(4,sizeof(float));
+ fdf = (float *) calloc(4,sizeof(float));
+
+
+
+ while ((c = getopt(argc,argv,"d:f:hk:l:m:n:q:st:u:v:")) != EOF)
+ switch(c) {
+ case 'd':
+ dflag = 1;
+ freq_filename = optarg;
+ break;
+ case 'f':
+ fflag=1;
+ sscanf(optarg,"%d,%d",&fflag_start,&fflag_end);
+ break;
+ case 'h':
+ hflag=1;
+ break;
+ case 'k':
+ kflag = 1;
+ sscanf(optarg,"%d",&sample_size);
+ break;
+ case 'l':
+ lflag = 1;
+ sscanf(optarg,"%d,%d",&mean,&stddev);
+ break;
+ case 'm':
+ mflag=1;
+ sscanf(optarg,"%d",&maxtargetlength);
+ break;
+ case 'n':
+ nflag=1;
+ sscanf(optarg,"%d",&maxquerylength);
+ break;
+ case 'q':
+ qflag = 1;
+ query_fn = optarg;
+ break;
+ case 's':
+ sflag = 1;
+ break;
+ case 't':
+ tflag = 1;
+ target_fn = optarg;
+ break;
+ case 'u':
+ uflag = 1;
+ sscanf(optarg,"%d",&iloop_upper_limit);
+ break;
+ case 'v':
+ vflag = 1;
+ sscanf(optarg,"%d",&bloop_upper_limit);
+ break;
+ case '?':
+ errflag = 1;
+ break;
+ }
+
+ if ((errflag || sflag && dflag || argc < 3) && !hflag) {
+ printf("\nOption error. Type %s -h for usage.\n\n", argv[0]);
+ exit(1);
+ }
+ else if (hflag) {
+ printf("\nUsage: %s [options] [target sequence] [query sequence].\n\noptions:\n\n -d <dinucleotide frequencies file>\n -f helix constraint\n -h help\n -k <sample size>\n -l <mean sequence length>,<std sequence length>\n -m <max targetlength>\n -n <max query length>\n -u <max internal loop size (per side)>\n -v <max bulge loop size>\n -s randomise targets (only with -t, without -d)\n -t <target file>\n -q <query file>\n\nIf no target file is given, random sequences are generated according\nto the given dinucleotide distribution. Then <sample size> sequences\nare generated whose lengths are normally distributed with given mean\nand standard deviation. Default sample size is 5000, default mean\nand std are 500 and 300, respectively.\n\nIf a target file is given, and additionally the -s option, random sequences are generated according to the dinucleotide distribution of the target file.\n\nIf only a target file is given, it is used directly as a random database.\n\nThe target can also be given directly (makes only sense with the -s option).\n\nEither a query file has to be given (FASTA format)\nor one query sequence directly.\n\nThe helix constraint format is \"from,to\", eg. -f 2,7 forces\nstructures to have a helix from position 2 to 7 with respect to the query.\n\n", argv[0]);
+ exit(0);
+ }
+
+ if (!uflag)
+ iloop_upper_limit = ILOOPUPPERLIMITDEFAULT;
+ if (!vflag)
+ bloop_upper_limit = BLOOPUPPERLIMITDEFAULT;
+
+ if (!lflag) {
+ mean = MEAN;
+ stddev = STDDEV;
+ }
+
+ if (!kflag)
+ sample_size = SAMPLESIZE;
+
+ if (tflag && !sflag)
+ normalised_energies = (float *) calloc(MAXTARGETNUMBER,sizeof(float));
+ else
+ normalised_energies = (float *) calloc(sample_size,sizeof(float));
+
+ if (!mflag)
+ maxtargetlength = MAXTARGET;
+ if (!nflag)
+ maxquerylength = MAXQUERY;
+
+ if (qflag) {
+ query_sq = (char *) calloc(maxquerylength+MAXLINE+1, sizeof(char));
+ querylength = maxquerylength;
+ }
+ else {
+ query_sq = (char *) calloc(strlen(argv[argc-1])+1,sizeof(char));
+ strcpy(query_ac,"command_line");
+ strcpy(query_sq,argv[argc-1]);
+ remove_whitespace(query_sq);
+ querylength = strlen(argv[argc-1]);
+ }
+
+ if (tflag)
+ target_sq = (char *) calloc(maxtargetlength+MAXLINE+1,sizeof(char));
+
+
+ if (!tflag && argv[argc-1-(!qflag)][0] != '-') {
+ /* target sequence given on command line */
+ target_sq = (char *) calloc(strlen(argv[argc-1-(!qflag)])+1,sizeof(char));
+ strcpy(target_ac,"command_line");
+ strcpy(target_sq,argv[argc-1-(!qflag)]);
+ remove_whitespace(target_sq);
+ targetlength = strlen(target_sq);
+ }
+
+ if (sflag) {
+ /* initialise dinucleotide frequencies: */
+ for (i=0; i<4; i++)
+ for (j=0; j<4; j++)
+ freq_di[i][j] = 0.0;
+
+ if (tflag) {
+ /* open target file: */
+ FILE *target = fopen(target_fn,"r");
+ if (target==NULL) {
+ printf("Error: Could not open target file. Aborting.\n");
+ exit(2);
+ }
+
+ /* iterate over target sequences: */
+ counter = 0;
+ while (!end(target)) {
+
+ nextAC(target,target_ac);
+ nextSQ(target,target_sq,maxtargetlength);
+
+ remove_whitespace(target_sq);
+
+ seqlen = strlen(target_sq);
+ /* count dinucleotides: */
+ for (k=0; k<seqlen-1; k++) {
+ letter_one = toupper(target_sq[k]);
+ letter_two = toupper(target_sq[k+1]);
+
+ if (letter_one == 'U')
+ letter_one = 'T';
+ if (letter_two == 'U')
+ letter_two = 'T';
+
+ index_one = (int) strchr(alphabet,letter_one);
+ index_two = (int) strchr(alphabet,letter_two);
+
+ if (index_one != 0 && index_two != 0) {
+ freq_di[index_one-(int) alphabet][index_two-(int) alphabet]++;
+ counter++;
+ }
+ }
+ }
+ /* close target file: */
+ fclose(target);
+ } /* if tflag */
+ else { /* !tflag */
+
+ counter = 0;
+ seqlen = strlen(target_sq);
+ /* count dinucleotides: */
+ for (k=0; k<seqlen-1; k++) {
+ letter_one = toupper(target_sq[k]);
+ letter_two = toupper(target_sq[k+1]);
+
+ if (letter_one == 'U')
+ letter_one = 'T';
+ if (letter_two == 'U')
+ letter_two = 'T';
+
+ index_one = (int) strchr(alphabet,letter_one);
+ index_two = (int) strchr(alphabet,letter_two);
+
+ if (index_one != 0 && index_two != 0) {
+ freq_di[index_one-(int) alphabet][index_two-(int) alphabet]++;
+ counter++;
+ }
+ }
+
+ }
+
+ /* turn counts into relative frequencies: */
+ for (i=0; i<4; i++)
+ for (j=0; j<4; j++)
+ freq_di[i][j] /= (float) counter;
+
+ } /* if sflag */
+
+
+ targetlength = maxtargetlength;
+
+ init_constants();
+ init_energies();
+
+ tableAlloc(targetlength,querylength);
+
+ /* allocate string space */
+ r1 = t1 = (char *) calloc(2*max(targetlength,querylength), sizeof(char));
+ r2 = t2 = (char *) calloc(2*max(targetlength,querylength), sizeof(char));
+ r3 = t3 = (char *) calloc(2*max(targetlength,querylength), sizeof(char));
+ r4 = t4 = (char *) calloc(2*max(targetlength,querylength), sizeof(char));
+
+ x = (char *) calloc(targetlength+2, sizeof(char));
+ y = (char *) calloc( querylength+2, sizeof(char));
+
+
+ if (tflag && sflag || !tflag && argv[argc-1-(!qflag)][0] != '-' && sflag)
+ free(target_sq);
+
+
+
+ if (dflag) {
+ /* read dinucleotide frequencies: */
+ f = fopen(freq_filename,"r");
+ read_dinucleotide_frequencies(freq_di,f);
+ fclose(f);
+ }
+
+
+ /* calculate single nucleotide frequencies: */
+ for (i=0; i<strlen(alphabet); i++) {
+ freq[i]=2*freq_di[i][i];
+ for (j=0; j<strlen(alphabet); j++)
+ if (i!=j)
+ freq[i] += freq_di[i][j];
+ for (j=0; j<strlen(alphabet); j++)
+ if (i!=j)
+ freq[i] += freq_di[j][i];
+ freq[i] /= 2.0;
+ }
+
+ /* make distribution functions: */
+ fdf[0] = freq[0];
+ for (i=1; i<strlen(alphabet); i++)
+ fdf[i]=fdf[i-1]+freq[i];
+ fdf[strlen(alphabet)-1]=1.0;
+
+ for (i=0; i<strlen(alphabet); i++) {
+ float row_sum = 0;
+ for (j=0; j<strlen(alphabet); j++)
+ row_sum+=freq_di[i][j];
+ fdf_di[i][0]=freq_di[i][0]/row_sum;
+ for (j=1; j<strlen(alphabet); j++)
+ fdf_di[i][j]=fdf_di[i][j-1]+freq_di[i][j]/row_sum;
+ fdf_di[i][strlen(alphabet)-1]=1.0;
+ }
+
+
+ sgenrand(time(NULL));
+
+ if (qflag) {
+
+ FILE *query = fopen( query_fn,"r");
+ if (query==NULL) {
+ printf("Error: Could not open query file. Aborting.\n");
+ exit(2);
+ }
+
+ while (!end(query)) {
+
+ nextAC(query,query_ac);
+ nextSQ(query,query_sq,maxquerylength);
+
+ remove_whitespace(query_sq);
+
+ n = strlen(query_sq);
+
+ if (fflag) {
+ helix_start = n - fflag_end;
+ helix_end = n - fflag_start + 1;
+ }
+ else {
+ helix_start = 0;
+ helix_end = 0;
+ }
+
+ if (n > maxquerylength) {
+ printf("query too long: %s\n", query_ac);
+ }
+ else {
+
+ y[0]=' ';
+ for (i=0;i<=n-1;i++) y[i+1] = query_sq[n-i-1];
+ y[n+1]=0;
+ convert_y();
+
+ if (tflag && !sflag) {
+ FILE *target = fopen(target_fn,"r");
+ if (target==NULL) {
+ printf("Error: Could not open target file. Aborting.\n");
+ exit(2);
+ }
+
+ k = 0;
+ while (!end(target) && k<MAXTARGETNUMBER) {
+
+ nextAC(target,target_ac);
+ nextSQ(target,target_sq,maxtargetlength);
+
+ remove_whitespace(target_sq);
+
+ m = strlen(target_sq);
+
+ if (m > maxtargetlength) {
+ printf("target too long: %s\n", target_ac);
+ }
+ else {
+ strcpy(x, " ");
+ strcat(x, target_sq);
+ convert_x();
+
+ for (i1=m; i1>=0; i1--) {
+ for (i2=n; i2>=0; i2--) {
+ calc_unpaired_left_bot(i1, m, i2, n);
+ calc_closed (i1, m, i2, n);
+ calc_unpaired_left_top(i1, m, i2, n);
+ }
+ }
+ v2 = calc_hybrid(0, m, 0, n);
+
+ normalised_energy = -v2/log(m*n);
+ normalised_energies[k] = normalised_energy;
+
+ free(target_sq);
+
+ /* initialize strings */
+ r1 = t1;
+ r2 = t2;
+ r3 = t3;
+ r4 = t4;
+
+ k++;
+ }
+ }
+ strcpy(output.query_ac,query_ac);
+ estimate_evd_parameters(&output.used_sample_size,&output.location,&output.scale,normalised_energies,k);
+ printf("%s %d %f %f\n",output.query_ac,output.used_sample_size,output.location,output.scale);
+/* printf("%s %f %f\n",query_ac,xi,theta); */
+
+ fclose(target);
+ } /* if tflag && !sflag */
+ else if (!tflag && !sflag && !dflag) {
+ m = strlen(target_sq);
+
+ k = 0;
+ if (m > maxtargetlength) {
+ printf("target too long: %s\n", target_ac);
+ }
+ else {
+ strcpy(x, " ");
+ strcat(x, target_sq);
+ convert_x();
+
+ for (i1=m; i1>=0; i1--) {
+ for (i2=n; i2>=0; i2--) {
+ calc_unpaired_left_bot(i1, m, i2, n);
+ calc_closed (i1, m, i2, n);
+ calc_unpaired_left_top(i1, m, i2, n);
+ }
+ }
+ v2 = calc_hybrid(0, m, 0, n);
+
+ normalised_energy = -v2/log(m*n);
+ normalised_energies[k] = normalised_energy;
+
+ free(target_sq);
+
+ /* initialize strings */
+ r1 = t1;
+ r2 = t2;
+ r3 = t3;
+ r4 = t4;
+
+ k++;
+ }
+
+ strcpy(output.query_ac,query_ac);
+ estimate_evd_parameters(&output.used_sample_size,&output.location,&output.scale,normalised_energies,k);
+ printf("%s %d %f %f\n",output.query_ac,output.used_sample_size,output.location,output.scale);
+
+/* printf("%s %f %f\n",query_ac,xi,theta); */
+
+ } /* if !tflag && !sflag %% !dflag*/
+ else { /* !tflag or sflag or dflag*/
+ k = 0;
+ while (k<sample_size) {
+ do seqlen = (int) (normal_random_number()*stddev+mean); while (seqlen < 1 || seqlen > maxtargetlength);
+ target_sq = random_sequence(seqlen,fdf,fdf_di);
+
+ m = strlen(target_sq);
+
+ strcpy(x, " ");
+ strcat(x, target_sq);
+ convert_x();
+
+ for (i1=m; i1>=0; i1--) {
+ for (i2=n; i2>=0; i2--) {
+ calc_unpaired_left_bot(i1, m, i2, n);
+ calc_closed (i1, m, i2, n);
+ calc_unpaired_left_top(i1, m, i2, n);
+ }
+ }
+ v2 = calc_hybrid(0, m, 0, n);
+
+ normalised_energy = -v2/log(m*n);
+ normalised_energies[k] = normalised_energy;
+
+/* printf("%f\n",normalised_energy); */
+
+ free(target_sq);
+
+ /* initialize strings */
+ r1 = t1;
+ r2 = t2;
+ r3 = t3;
+ r4 = t4;
+
+ k++;
+ }
+ strcpy(output.query_ac,query_ac);
+ estimate_evd_parameters(&output.used_sample_size,&output.location,&output.scale,normalised_energies,k);
+ printf("%s %d %f %f\n",output.query_ac,output.used_sample_size,output.location,output.scale);
+ }
+ }
+
+ }
+ fclose(query);
+ } /* if qflag */
+ else { /* !qflag */
+ n = strlen(query_sq);
+
+ if (fflag) {
+ helix_start = n - fflag_end;
+ helix_end = n - fflag_start + 1;
+ }
+ else {
+ helix_start = 0;
+ helix_end = 0;
+ }
+
+
+ y[0]=' ';
+ for (i=0;i<=n-1;i++) y[i+1] = query_sq[n-i-1];
+ y[n+1]=0;
+ convert_y();
+
+ if (tflag && !sflag) {
+ FILE *target = fopen(target_fn,"r");
+ if (target==NULL) {
+ printf("Error: Could not open target file. Aborting.\n");
+ exit(2);
+ }
+
+ k = 0;
+ while (!end(target) && k<MAXTARGETNUMBER) {
+
+ nextAC(target,target_ac);
+ nextSQ(target,target_sq,maxtargetlength);
+
+ remove_whitespace(target_sq);
+
+ m = strlen(target_sq);
+
+ if (m > maxtargetlength) {
+ printf("target too long: %s\n", target_ac);
+ }
+ else {
+ strcpy(x, " ");
+ strcat(x, target_sq);
+ convert_x();
+
+ for (i1=m; i1>=0; i1--) {
+ for (i2=n; i2>=0; i2--) {
+ calc_unpaired_left_bot(i1, m, i2, n);
+ calc_closed (i1, m, i2, n);
+ calc_unpaired_left_top(i1, m, i2, n);
+ }
+ }
+ v2 = calc_hybrid(0, m, 0, n);
+
+ normalised_energy = -v2/log(m*n);
+ normalised_energies[k] = normalised_energy;
+
+ /* initialize strings */
+ r1 = t1;
+ r2 = t2;
+ r3 = t3;
+ r4 = t4;
+
+ k++;
+ }
+ }
+ strcpy(output.query_ac,query_ac);
+ estimate_evd_parameters(&output.used_sample_size,&output.location,&output.scale,normalised_energies,k);
+ printf("%s %d %f %f\n",output.query_ac,output.used_sample_size,output.location,output.scale);
+
+ fclose(target);
+ } /* if tflag && !sflag */
+ else if (!tflag && !sflag && !dflag) {
+ m = strlen(target_sq);
+
+ k = 0;
+ if (m > maxtargetlength) {
+ printf("target too long: %s\n", target_ac);
+ }
+ else {
+ strcpy(x, " ");
+ strcat(x, target_sq);
+ convert_x();
+
+ for (i1=m; i1>=0; i1--) {
+ for (i2=n; i2>=0; i2--) {
+ calc_unpaired_left_bot(i1, m, i2, n);
+ calc_closed (i1, m, i2, n);
+ calc_unpaired_left_top(i1, m, i2, n);
+ }
+ }
+ v2 = calc_hybrid(0, m, 0, n);
+
+ normalised_energy = -v2/log(m*n);
+ normalised_energies[k] = normalised_energy;
+
+ free(target_sq);
+
+ /* initialize strings */
+ r1 = t1;
+ r2 = t2;
+ r3 = t3;
+ r4 = t4;
+
+ k++;
+ }
+ strcpy(output.query_ac,query_ac);
+ estimate_evd_parameters(&output.used_sample_size,&output.location,&output.scale,normalised_energies,k);
+ printf("%s %d %f %f\n",output.query_ac,output.used_sample_size,output.location,output.scale);
+ } /* if !tflag && !sflag && !dflag */
+ else { /* !tflag or sflag or dflag */
+ k = 0;
+ while (k<sample_size) {
+ do seqlen = (int) (normal_random_number()*stddev+mean); while (seqlen < 1 || seqlen > maxtargetlength);
+ target_sq = random_sequence(seqlen,fdf,fdf_di);
+
+ m = strlen(target_sq);
+
+ strcpy(x, " ");
+ strcat(x, target_sq);
+ convert_x();
+
+ for (i1=m; i1>=0; i1--) {
+ for (i2=n; i2>=0; i2--) {
+ calc_unpaired_left_bot(i1, m, i2, n);
+ calc_closed (i1, m, i2, n);
+ calc_unpaired_left_top(i1, m, i2, n);
+ }
+ }
+ v2 = calc_hybrid(0, m, 0, n);
+
+ normalised_energy = -v2/log(m*n);
+ normalised_energies[k] = normalised_energy;
+
+ free(target_sq);
+
+ /* initialize strings */
+ r1 = t1;
+ r2 = t2;
+ r3 = t3;
+ r4 = t4;
+
+ k++;
+ }
+ strcpy(output.query_ac,query_ac);
+ estimate_evd_parameters(&output.used_sample_size,&output.location,&output.scale,normalised_energies,k);
+ printf("%s %d %f %f\n",output.query_ac,output.used_sample_size,output.location,output.scale);
+ } /* !tflag or sflag */
+ }
+
+ if (tflag && !sflag)
+ free(target_sq);
+
+ for (i=0; i<4; i++) {
+ free(freq_di[i]);
+ free(fdf_di[i]);
+ }
+ free(freq_di);
+ free(fdf_di);
+ free(freq);
+ free(fdf);
+
+ free(normalised_energies);
+
+ free(query_sq);
+
+ return 0;
+}
+
+
+
Added: trunk/packages/rnahybrid/branches/upstream/current/src/rnaeffective.c
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/src/rnaeffective.c (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/src/rnaeffective.c 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,659 @@
+/* Copyright (C) 2004 Marc Rehmsmeier, Peter Steffen, Matthias Hoechsmann */
+
+/* This program is free software; you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation; either version 2 of the License, or (at your option) any later version. */
+
+/* This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details. */
+
+/* You should have received a copy of the GNU General Public License along with this program; if not, write to the Free Software Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA */
+
+#include "hybrid_core.h"
+#include "numerical.h"
+#include "random.h"
+#include "globals.h"
+#include "minmax.h"
+#include "mt19937-1.h"
+#include <stdio.h>
+#include <sys/types.h>
+#include <time.h>
+#include <math.h>
+#include <stdlib.h>
+
+
+static char const rcsid[] = "$Id: rnaeffective.c,v 1.6 2004/11/16 15:41:12 marc Exp $";
+
+
+
+int main(int argc, char **argv)
+{
+ extern char *optarg;
+ extern int optind;
+ int c;
+ int
+ dflag = 0, // file with dinucleotide parameters
+ fflag = 0, // force helix, arguments: from,to (positions in miRNA)
+ hflag = 0, // help
+ kflag = 0, // number of sequences to generate
+ lflag = 0, // length distribution parameters (mean, std deviation)
+ mflag = 0, // max target length
+ nflag = 0, // max query length
+ qflag = 0, // query input file
+ sflag = 0, // make random sequences according to target file
+ tflag = 0, // target input file
+ uflag = 0, // upper size for internal loops (per side)
+ vflag = 0, // upper size for bulge loops
+ errflag = 0;
+
+ int
+ maxtargetlength,
+ maxquerylength;
+ char
+ *query_fn, // query filename
+ *target_fn;
+
+ char target_ac[MAXLINE];
+ char query_ac[MAXLINE];
+
+ char *target_sq;
+ char *query_sq;
+
+ char *freq_filename;
+
+ int i1, i2;
+ double v2, normalised_energy;
+
+ int
+ fflag_start,
+ fflag_end;
+ int
+ targetlength,
+ querylength;
+
+ int mean, stddev, sample_size, used_sample_size;
+
+ float pvalue;
+
+ float *xi, *theta;
+
+ FILE *f;
+
+ int i,j,k,l,seqlen;
+
+ char letter_one, letter_two;
+
+ int index_one, index_two;
+
+ int counter;
+
+ float exponent, effective_number;
+
+ float *xcdf, *ycdf, bin_number, error_sum, smallest_error_sum;
+
+
+
+ float **normalised_energies;
+ float *temp_energies;
+ float *maximal_pvalues;
+ float *joint_pvalues;
+
+ float **freq_di = (float **) calloc(4,sizeof(float*));
+ float **fdf_di = (float **) calloc(4,sizeof(float*));
+ float *freq;
+ float *fdf;
+
+ for (i=0; i<4; i++) {
+ freq_di[i] = (float *) calloc(4,sizeof(float));
+ fdf_di[i] = (float *) calloc(4,sizeof(float));
+ }
+ freq = (float *) calloc(4,sizeof(float));
+ fdf = (float *) calloc(4,sizeof(float));
+
+
+
+ while ((c = getopt(argc,argv,"d:f:hk:l:m:n:q:st:u:v:")) != EOF)
+ switch(c) {
+ case 'd':
+ dflag = 1;
+ freq_filename = optarg;
+ break;
+ case 'f':
+ fflag=1;
+ sscanf(optarg,"%d,%d",&fflag_start,&fflag_end);
+ break;
+ case 'h':
+ hflag=1;
+ break;
+ case 'k':
+ kflag = 1;
+ sscanf(optarg,"%d",&sample_size);
+ break;
+ case 'l':
+ lflag = 1;
+ sscanf(optarg,"%d,%d",&mean,&stddev);
+ break;
+ case 'm':
+ mflag=1;
+ sscanf(optarg,"%d",&maxtargetlength);
+ break;
+ case 'n':
+ nflag=1;
+ sscanf(optarg,"%d",&maxquerylength);
+ break;
+ case 'q':
+ qflag = 1;
+ query_fn = optarg;
+ break;
+ case 's':
+ sflag = 1;
+ break;
+ case 't':
+ tflag = 1;
+ target_fn = optarg;
+ break;
+ case 'u':
+ uflag = 1;
+ sscanf(optarg,"%d",&iloop_upper_limit);
+ break;
+ case 'v':
+ vflag = 1;
+ sscanf(optarg,"%d",&bloop_upper_limit);
+ break;
+ case '?':
+ errflag = 1;
+ break;
+ }
+
+ if ((errflag || sflag && dflag || argc < 3) && !hflag) {
+ printf("\nOption error. Type %s -h for usage.\n\n", argv[0]);
+ exit(1);
+ }
+ else if (hflag) {
+ printf("\nUsage: %s [options] [query sequence].\n\noptions:\n\n -d <dinucleotide frequencies file>\n -f helix constraint\n -h help\n -k <sample size>\n -l <mean sequence length>,<std sequence length>\n -m <max targetlength>\n -n <max query length>\n -u <max internal loop size (per side)>\n -v <max bulge loop size>\n -s randomise queries (only with -q, without -d)\n -t <target file>\n -q <query file>\n\nIf no query file is given, random sequences are generated according\nto the given dinucleotide distribution. Then <sample size> sequences\nare generated whose lengths are normally distributed with given mean\nand standard deviation. Default sample size is 5000, default mean\nand std are 22 and 0, respectively.\n\nIf a query file is given, and additionally the -s option, random sequences\nare generated according to the dinucleotide distribution of the query file.\n\nIf only a query file is given, it is used directly as a random database.\n\nThe query can also be given directly (makes only sense with the -s option).\n\nA target file has to be given (FASTA format).\n\n\nThe helix constraint format is \"from,to\", eg. -f 2,7 forces\nstructures to have a helix from position 2 to 7 with respect to the query.\n\n", argv[0]);
+ exit(0);
+ }
+
+ if (!uflag)
+ iloop_upper_limit = ILOOPUPPERLIMITDEFAULT;
+ if (!vflag)
+ bloop_upper_limit = BLOOPUPPERLIMITDEFAULT;
+
+ if (!lflag) {
+ mean = MIRNA_LENGTH_MEAN;
+ stddev = MIRNA_LENGTH_STDDEV;
+ }
+
+ if (!kflag)
+ sample_size = SAMPLESIZE;
+
+ normalised_energies = (float **) calloc(MAXORTHOLOGNUMBER,sizeof(float *));
+ xi = (float *) calloc(MAXORTHOLOGNUMBER,sizeof(float));
+ theta = (float *) calloc(MAXORTHOLOGNUMBER,sizeof(float));
+
+ if (qflag && !sflag) {
+ for (i=0; i<MAXORTHOLOGNUMBER; i++)
+ normalised_energies[i] = (float *) calloc(MAXQUERYNUMBER,sizeof(float));
+ temp_energies = (float *) calloc(MAXQUERYNUMBER,sizeof(float));
+ maximal_pvalues = (float *) calloc(MAXQUERYNUMBER,sizeof(float));
+ joint_pvalues = (float *) calloc(MAXQUERYNUMBER,sizeof(float));
+ }
+ else {
+ for (i=0; i<MAXORTHOLOGNUMBER; i++)
+ normalised_energies[i] = (float *) calloc(sample_size,sizeof(float));
+ temp_energies = (float *) calloc(sample_size,sizeof(float));
+ maximal_pvalues = (float *) calloc(sample_size,sizeof(float));
+ joint_pvalues = (float *) calloc(sample_size,sizeof(float));
+ }
+
+ if (!mflag)
+ maxtargetlength = MAXTARGET;
+ if (!nflag)
+ maxquerylength = MAXQUERY;
+
+ if (qflag) {
+ query_sq = (char *) calloc(maxquerylength+MAXLINE+1, sizeof(char));
+ querylength = maxquerylength;
+ }
+ else {
+ query_sq = (char *) calloc(strlen(argv[argc-1])+1,sizeof(char));
+ strcpy(query_ac,"command_line");
+ strcpy(query_sq,argv[argc-1]);
+ remove_whitespace(query_sq);
+ querylength = strlen(argv[argc-1]);
+ }
+
+ if (tflag) {
+ target_sq = (char *) calloc(maxtargetlength+MAXLINE+1,sizeof(char));
+ targetlength = maxtargetlength;
+ }
+
+
+ if (!tflag && argv[argc-1-(!qflag)][0] != '-') {
+ /* target sequence given on command line */
+ target_sq = (char *) calloc(strlen(argv[argc-1-(!qflag)])+1,sizeof(char));
+ strcpy(target_ac,"command_line");
+ strcpy(target_sq,argv[argc-1-(!qflag)]);
+ remove_whitespace(target_sq);
+ targetlength = strlen(target_sq);
+ }
+
+
+ if (sflag) {
+ /* initialise dinucleotide frequencies: */
+ for (i=0; i<4; i++)
+ for (j=0; j<4; j++)
+ freq_di[i][j] = 0.0;
+
+ if (qflag) {
+ /* open query file: */
+ FILE *query = fopen(query_fn,"r");
+ if (query==NULL) {
+ printf("Error: Could not open query file. Aborting.\n");
+ exit(2);
+ }
+
+ /* iterate over query sequences: */
+ counter = 0;
+ while (!end(query)) {
+
+ nextAC(query,query_ac);
+ nextSQ(query,query_sq,maxquerylength);
+
+ remove_whitespace(query_sq);
+
+ seqlen = strlen(query_sq);
+ /* count dinucleotides: */
+ for (k=0; k<seqlen-1; k++) {
+ letter_one = toupper(query_sq[k]);
+ letter_two = toupper(query_sq[k+1]);
+
+ if (letter_one == 'U')
+ letter_one = 'T';
+ if (letter_two == 'U')
+ letter_two = 'T';
+
+ index_one = (int) strchr(alphabet,letter_one);
+ index_two = (int) strchr(alphabet,letter_two);
+
+ if (index_one != 0 && index_two != 0) {
+ freq_di[index_one-(int) alphabet][index_two-(int) alphabet]++;
+ counter++;
+ }
+ }
+ }
+ /* close query file: */
+ fclose(query);
+ } /* if qflag */
+ else { /* !qflag */
+
+ counter = 0;
+ seqlen = strlen(query_sq);
+ /* count dinucleotides: */
+ for (k=0; k<seqlen-1; k++) {
+ letter_one = toupper(query_sq[k]);
+ letter_two = toupper(query_sq[k+1]);
+
+ if (letter_one == 'U')
+ letter_one = 'T';
+ if (letter_two == 'U')
+ letter_two = 'T';
+
+ index_one = (int) strchr(alphabet,letter_one);
+ index_two = (int) strchr(alphabet,letter_two);
+
+ if (index_one != 0 && index_two != 0) {
+ freq_di[index_one-(int) alphabet][index_two-(int) alphabet]++;
+ counter++;
+ }
+ }
+
+ }
+
+ /* turn counts into relative frequencies: */
+ for (i=0; i<4; i++)
+ for (j=0; j<4; j++)
+ freq_di[i][j] /= (float) counter;
+
+ } /* if sflag */
+
+
+ init_constants();
+ init_energies();
+
+ tableAlloc(targetlength,querylength);
+
+ /* allocate string space */
+ r1 = t1 = (char *) calloc(2*max(targetlength,querylength), sizeof(char));
+ r2 = t2 = (char *) calloc(2*max(targetlength,querylength), sizeof(char));
+ r3 = t3 = (char *) calloc(2*max(targetlength,querylength), sizeof(char));
+ r4 = t4 = (char *) calloc(2*max(targetlength,querylength), sizeof(char));
+
+ x = (char *) calloc(targetlength+2, sizeof(char));
+ y = (char *) calloc( querylength+2, sizeof(char));
+
+
+ if (qflag && sflag || !qflag && argv[argc-1][0] != '-' && sflag)
+ free(query_sq);
+
+
+ if (dflag) {
+ /* read dinucleotide frequencies: */
+ f = fopen(freq_filename,"r");
+ read_dinucleotide_frequencies(freq_di,f);
+ fclose(f);
+ }
+
+
+ /* calculate single nucleotide frequencies: */
+ for (i=0; i<strlen(alphabet); i++) {
+ freq[i]=2*freq_di[i][i];
+ for (j=0; j<strlen(alphabet); j++)
+ if (i!=j)
+ freq[i] += freq_di[i][j];
+ for (j=0; j<strlen(alphabet); j++)
+ if (i!=j)
+ freq[i] += freq_di[j][i];
+ freq[i] /= 2.0;
+ }
+
+ /* make distribution functions: */
+ fdf[0] = freq[0];
+ for (i=1; i<strlen(alphabet); i++)
+ fdf[i]=fdf[i-1]+freq[i];
+ fdf[strlen(alphabet)-1]=1.0;
+
+ for (i=0; i<strlen(alphabet); i++) {
+ float row_sum = 0;
+ for (j=0; j<strlen(alphabet); j++)
+ row_sum+=freq_di[i][j];
+ fdf_di[i][0]=freq_di[i][0]/row_sum;
+ for (j=1; j<strlen(alphabet); j++)
+ fdf_di[i][j]=fdf_di[i][j-1]+freq_di[i][j]/row_sum;
+ fdf_di[i][strlen(alphabet)-1]=1.0;
+ }
+
+
+ sgenrand(time(NULL));
+
+ /* Search: */
+
+ if (qflag && !sflag) {
+
+ /* open query file: */
+ FILE *query = fopen(query_fn,"r");
+ if (query==NULL) {
+ printf("Error: Could not open query file. Aborting.\n");
+ exit(2);
+ }
+
+ /* iterate over query sequences: */
+ counter = 0;
+ while (!end(query)) {
+
+ nextAC(query,query_ac);
+ nextSQ(query,query_sq,maxquerylength);
+
+ remove_whitespace(query_sq);
+
+ seqlen = strlen(query_sq);
+
+ n = strlen(query_sq);
+
+ if (fflag) {
+ helix_start = n - fflag_end;
+ helix_end = n - fflag_start + 1;
+ }
+ else {
+ helix_start = 0;
+ helix_end = 0;
+ }
+
+ y[0]=' ';
+ for (i=0;i<=n-1;i++) y[i+1] = query_sq[n-i-1];
+ y[n+1]=0;
+ convert_y();
+
+ if (tflag) {
+
+ FILE *target = fopen(target_fn,"r");
+ if (target==NULL) {
+ printf("Error: Could not open target file. Aborting.\n");
+ exit(2);
+ }
+
+ k = 0;
+ while (!end(target) && k<MAXTARGETNUMBER) {
+
+ nextAC(target,target_ac);
+ nextSQ(target,target_sq,maxtargetlength);
+
+ remove_whitespace(target_sq);
+
+ m = strlen(target_sq);
+
+ if (m > maxtargetlength) {
+ printf("target too long: %s\n", target_ac);
+ }
+ else {
+ strcpy(x, " ");
+ strcat(x, target_sq);
+ convert_x();
+
+ for (i1=m; i1>=0; i1--) {
+ for (i2=n; i2>=0; i2--) {
+ calc_unpaired_left_bot(i1, m, i2, n);
+ calc_closed (i1, m, i2, n);
+ calc_unpaired_left_top(i1, m, i2, n);
+ }
+ }
+ v2 = calc_hybrid(0, m, 0, n);
+
+ normalised_energy = -v2/log(m*n);
+ normalised_energies[k][l] = normalised_energy;
+
+ /* initialize strings */
+ r1 = t1;
+ r2 = t2;
+ r3 = t3;
+ r4 = t4;
+
+ k++;
+ }
+ }
+ fclose(target);
+ }
+ else { /* !tflag */
+ printf("Shouldn't happen.\n");
+ exit(1);
+ }
+
+ free(query_sq);
+
+ l++;
+ }
+ for (i=0; i<k; i++) {
+ for (j=0; j<l; j++)
+ temp_energies[j] = normalised_energies[i][j];
+ estimate_evd_parameters(&used_sample_size,&xi[i],&theta[i],temp_energies,l);
+/* printf("%f %f\n",xi[i],theta[i]); */
+ }
+
+ /* calculate p-values: */
+ for (j=0; j<l; j++) {
+ for (i=0; i<k; i++) {
+ pvalue = 1-exp(-exp(-(normalised_energies[i][j]-xi[i])/theta[i]));
+ if (i==0 || pvalue > maximal_pvalues[j])
+ maximal_pvalues[j] = pvalue;
+ }
+ }
+
+/* for (i=0; i<sample_size; i++) */
+/* printf("%f\n",maximal_pvalues[i]); */
+
+
+ /* find effective number of orthologs: */
+ effective_number = -1.0;
+ for (exponent=1.0; exponent<(float) k+0.01; exponent=exponent+0.1) {
+
+ /* joint pvalues: */
+ for (j=0; j<l; j++)
+ joint_pvalues[j] = pow(maximal_pvalues[j],exponent);
+
+ /* empirical cdf: */
+ empirical_cumulative_distribution_function(&xcdf,&ycdf,&bin_number,joint_pvalues,l);
+
+ /* weighted squared error: */
+ error_sum = 0.0;
+ for (j=0; j<bin_number; j++)
+ error_sum += 1.0/xcdf[j]*pow(ycdf[j+1]-xcdf[j],2.0);
+
+ printf("%f %f\n",exponent,error_sum);
+
+ /* check for new minimum: */
+ if (effective_number == -1.0 || error_sum < smallest_error_sum) {
+ smallest_error_sum = error_sum;
+ effective_number = exponent;
+ }
+ }
+
+ printf("Effective number: %f\n",effective_number);
+
+ }
+ else if (qflag && sflag || !qflag && sflag) {
+
+ l = 0;
+ while (l<sample_size) {
+ do seqlen = (int) (normal_random_number()*stddev+mean); while (seqlen < 1 || seqlen > maxquerylength);
+ query_sq = random_sequence(seqlen,fdf,fdf_di);
+
+ n = strlen(query_sq);
+
+ if (fflag) {
+ helix_start = n - fflag_end;
+ helix_end = n - fflag_start + 1;
+ }
+ else {
+ helix_start = 0;
+ helix_end = 0;
+ }
+
+ y[0]=' ';
+ for (i=0;i<=n-1;i++) y[i+1] = query_sq[n-i-1];
+ y[n+1]=0;
+ convert_y();
+
+ if (tflag) {
+
+ FILE *target = fopen(target_fn,"r");
+ if (target==NULL) {
+ printf("Error: Could not open target file. Aborting.\n");
+ exit(2);
+ }
+
+ k = 0;
+ while (!end(target) && k<MAXTARGETNUMBER) {
+
+ nextAC(target,target_ac);
+ nextSQ(target,target_sq,maxtargetlength);
+
+ remove_whitespace(target_sq);
+
+ m = strlen(target_sq);
+
+ if (m > maxtargetlength) {
+ printf("target too long: %s\n", target_ac);
+ }
+ else {
+ strcpy(x, " ");
+ strcat(x, target_sq);
+ convert_x();
+
+ for (i1=m; i1>=0; i1--) {
+ for (i2=n; i2>=0; i2--) {
+ calc_unpaired_left_bot(i1, m, i2, n);
+ calc_closed (i1, m, i2, n);
+ calc_unpaired_left_top(i1, m, i2, n);
+ }
+ }
+ v2 = calc_hybrid(0, m, 0, n);
+
+ normalised_energy = -v2/log(m*n);
+ normalised_energies[k][l] = normalised_energy;
+
+ /* initialize strings */
+ r1 = t1;
+ r2 = t2;
+ r3 = t3;
+ r4 = t4;
+
+ k++;
+ }
+ }
+ fclose(target);
+ }
+ else { /* !tflag */
+ printf("Shouldn't happen.\n");
+ exit(1);
+ }
+
+ free(query_sq);
+
+ l++;
+ }
+ for (i=0; i<k; i++) {
+ for (j=0; j<l; j++)
+ temp_energies[j] = normalised_energies[i][j];
+ estimate_evd_parameters(&used_sample_size,&xi[i],&theta[i],temp_energies,l);
+/* printf("%f %f\n",xi[i],theta[i]); */
+ }
+
+ /* calculate p-values: */
+ for (j=0; j<l; j++) {
+ for (i=0; i<k; i++) {
+ pvalue = 1-exp(-exp(-(normalised_energies[i][j]-xi[i])/theta[i]));
+ if (i==0 || pvalue > maximal_pvalues[j])
+ maximal_pvalues[j] = pvalue;
+ }
+ }
+
+/* for (i=0; i<sample_size; i++) */
+/* printf("%f\n",maximal_pvalues[i]); */
+
+
+ /* find effective number of orthologs: */
+ effective_number = -1.0;
+ for (exponent=1.0; exponent<(float) k+0.01; exponent=exponent+0.1) {
+
+ /* joint pvalues: */
+ for (j=0; j<l; j++)
+ joint_pvalues[j] = pow(maximal_pvalues[j],exponent);
+
+ /* empirical cdf: */
+ empirical_cumulative_distribution_function(&xcdf,&ycdf,&bin_number,joint_pvalues,l);
+
+ /* weighted squared error: */
+ error_sum = 0.0;
+ for (j=0; j<bin_number; j++)
+ error_sum += 1.0/xcdf[j]*pow(ycdf[j+1]-xcdf[j],2.0);
+
+ printf("%f %f\n",exponent,error_sum);
+
+ /* check for new minimum: */
+ if (effective_number == -1.0 || error_sum < smallest_error_sum) {
+ smallest_error_sum = error_sum;
+ effective_number = exponent;
+ }
+ }
+
+ printf("Effective number: %f\n",effective_number);
+
+
+ }
+ else { /* !qflag && !sflag */
+ printf("Refusing to base analysis on one query sequence. Aborting.\n");
+ exit(2);
+ }
+
+
+
+
+
+}
Added: trunk/packages/rnahybrid/branches/upstream/current/src/rnahybrid.c
===================================================================
--- trunk/packages/rnahybrid/branches/upstream/current/src/rnahybrid.c (rev 0)
+++ trunk/packages/rnahybrid/branches/upstream/current/src/rnahybrid.c 2007-06-01 00:53:51 UTC (rev 291)
@@ -0,0 +1,492 @@
+/* Copyright (C) 2004 Marc Rehmsmeier, Peter Steffen, Matthias Hoechsmann */
+
+/* This program is free software; you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation; either version 2 of the License, or (at your option) any later version. */
+
+/* This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details. */
+
+/* You should have received a copy of the GNU General Public License along with this program; if not, write to the Free Software Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA */
+
+#include <stdio.h>
+#include <string.h>
+#include "config.h"
+#include "plot.h"
+#include "minmax.h"
+#include "fasta.h"
+#include "input.h"
+#include "energy.h"
+#include "globals.h"
+#include "hybrid_core.h"
+
+
+static char const rcsid[] = "$Id: rnahybrid.c,v 1.1.1.9.1.13 2004/11/15 20:41:38 marc Exp $";
+
+
+float maximal_duplex_energy(char *seq);
+
+
+int main(int argc, char **argv)
+{
+ int i;
+
+ extern char *optarg;
+ extern int optind;
+ int c;
+ int
+ bflag = 0, // number of hits per target to show
+ cflag = 0, // compact output
+ dflag = 0, // parameters of extreme value distribution
+ // for p-value calculation
+ eflag = 0, // report all hits with energy better (ie. lower) than or equal to e
+ fflag = 0, // force helix, arguments: from,to (positions in miRNA)
+ gflag = 0, // make plots (graphics) of hybridisations
+ hflag = 0, // help
+ mflag = 0, // max target length
+ nflag = 0, // max query length
+ pflag = 0, // report all hits with p-values better than or equal to p
+ sflag = 0, // data set flag, for organism and sequence specific settings
+ qflag = 0, // query input file
+ tflag = 0, // target input file
+ uflag = 0, // upper size for internal loops (per side)
+ vflag = 0, // upper size for bulge loops
+ errflag = 0;
+ int
+ maxtargetlength,
+ maxquerylength;
+ char
+ *target_fn, // target filename
+ *query_fn; // query filename
+ float
+ energy_cutoff = 0.0,
+ pvalue_cutoff = 1.0,
+ xi, theta,
+ mde;
+
+ int
+ hit_number = 1;
+
+ char target_ac[MAXLINE];
+ char query_ac[MAXLINE];
+
+ char *target_sq;
+ char *query_sq;
+
+ char *gflag_argument;
+ char *plotfileextension;
+
+ char *setname;
+
+ int
+ targetlength,
+ querylength,
+ plot_format;
+
+ int
+ fflag_start,
+ fflag_end;
+
+ float xi_slope, xi_intercept, theta_slope, theta_intercept;
+
+
+ while ((c = getopt(argc,argv,"b:cd:e:f:g:hm:n:p:q:s:t:u:v:")) != EOF)
+ switch(c) {
+ case 'b':
+ bflag=1;
+ sscanf(optarg,"%d",&hit_number);
+ break;
+ case 'c':
+ cflag=1;
+ break;
+ case 'd':
+ dflag=1;
+ sscanf(optarg,"%f,%f",&xi,&theta);
+ break;
+ case 'e':
+ eflag=1;
+ sscanf(optarg,"%f",&energy_cutoff);
+ break;
+ case 'f':
+ fflag=1;
+ sscanf(optarg,"%d,%d",&fflag_start,&fflag_end);
+ break;
+ case 'g':
+ gflag=1;
+ gflag_argument = optarg;
+ break;
+ case 'h':
+ hflag=1;
+ break;
+ case 'm':
+ mflag=1;
+ sscanf(optarg,"%d",&maxtargetlength);
+ break;
+ case 'n':
+ nflag=1;
+ sscanf(optarg,"%d",&maxquerylength);
+ break;
+ case 'p':
+ pflag=1;
+ sscanf(optarg,"%f",&pvalue_cutoff);
+ break;
+ case 'q':
+ qflag = 1;
+ query_fn = optarg;
+ break;
+ case 's':
+ sflag=1;
+ setname = optarg;
+ break;
+ case 't':
+ tflag = 1;
+ target_fn = optarg;
+ break;
+ case 'u':
+ uflag = 1;
+ sscanf(optarg,"%d",&iloop_upper_limit);
+ break;
+ case 'v':
+ vflag = 1;
+ sscanf(optarg,"%d",&bloop_upper_limit);
+ break;
+ case '?':
+ errflag = 1;
+ break;
+ }
+
+ if (eflag && (energy_cutoff > 0)) {
+ printf("Warning: energy cut-off positive. I'm converting it to minus the value you gave.\n");
+ energy_cutoff = -energy_cutoff;
+ }
+
+ if (!uflag)
+ iloop_upper_limit = ILOOPUPPERLIMITDEFAULT;
+ if (!vflag)
+ bloop_upper_limit = BLOOPUPPERLIMITDEFAULT;
+
+
+#ifdef HAVE_LIBG2
+ if (gflag) {
+ if (strcmp(gflag_argument,"ps")==0)
+ plot_format = PSPLOT;
+#ifdef HAVE_LIBGD
+ else if (strcmp(gflag_argument,"png")==0)
+ plot_format = PNGPLOT;
+ else if (strcmp(gflag_argument,"jpg")==0)
+ plot_format = JPGPLOT;
+ else if (strcmp(gflag_argument,"all")==0)
+ plot_format = ALLPLOT;
+#endif
+ else {
+ printf("\nWrong plot format.\n");
+ errflag = 1;
+ }
+ }
+#endif
+
+ if (errflag || argc < 3 && !hflag) {
+ printf("\nOption error. Type %s -h for usage.\n\n", argv[0]);
+ exit(1);
+ }
+ else if (hflag) {
+ printf("\nUsage: %s [options] [target sequence] [query sequence].\n\noptions:\n\n -b <number of hits per target>\n -c compact output\n -d <xi>,<theta>\n -f helix constraint\n -h help\n -m <max targetlength>\n -n <max query length>\n -u <max internal loop size (per side)>\n -v <max bulge loop size>\n -e <energy cut-off>\n -p <p-value cut-off>\n -s (3utr_fly|3utr_worm|3utr_human)\n -g (ps|png|jpg|all)\n -t <target file>\n -q <query file>\n\nEither a target file has to be given (FASTA format)\nor one target sequence directly.\n\nEither a query file has to be given (FASTA format)\nor one query sequence directly.\n\nThe helix constraint format is \"from,to\", eg. -f 2,7 forces\nstructures to have a helix from position 2 to 7 with respect to the query.\n\n<xi> and <theta> are the position and shape parameters, respectively,\nof the extreme value distribution assumed for p-value calculation.\nIf omitted, they are estimated from the maximal duplex energy of the query.\nIn that case, a data set name has to be given with the -s flag.\n\n", argv[0]);
+
+#ifndef HAVE_LIBG2
+ printf("\nPS graphical output not supported.\n\n");
+#endif
+
+#ifndef HAVE_LIBGD
+ printf("\nPNG and JPG graphical output not supported.\n\n");
+#endif
+ exit(0);
+ }
+
+ if (!dflag && !sflag) {
+ printf("Error: without -d you have to give -s option. Aborting.\n");
+ exit(2);
+ }
+
+ if (sflag) {
+ if (strcmp(setname,SETNAME_3UTR_FLY) == 0) {
+ xi_slope = XI_SLOPE_3UTR_FLY;
+ xi_intercept = XI_INTERCEPT_3UTR_FLY;
+ theta_slope = THETA_SLOPE_3UTR_FLY;
+ theta_intercept = THETA_INTERCEPT_3UTR_FLY;
+ }
+ else if (strcmp(setname,SETNAME_3UTR_WORM) == 0) {
+ xi_slope = XI_SLOPE_3UTR_WORM;
+ xi_intercept = XI_INTERCEPT_3UTR_WORM;
+ theta_slope = THETA_SLOPE_3UTR_WORM;
+ theta_intercept = THETA_INTERCEPT_3UTR_WORM;
+ }
+ else if (strcmp(setname,SETNAME_3UTR_HUMAN) == 0) {
+ xi_slope = XI_SLOPE_3UTR_HUMAN;
+ xi_intercept = XI_INTERCEPT_3UTR_HUMAN;
+ theta_slope = THETA_SLOPE_3UTR_HUMAN;
+ theta_intercept = THETA_INTERCEPT_3UTR_HUMAN;
+ }
+ else {
+ printf("Error: unknown set name. Aborting.\n");
+ exit(2);
+ }
+ }
+
+ if (!mflag)
+ maxtargetlength = MAXTARGET;
+ if (!nflag)
+ maxquerylength = MAXQUERY;
+
+ if (tflag && qflag) {
+ target_sq = (char *) calloc(maxtargetlength+MAXLINE+1,sizeof(char));
+ query_sq = (char *) calloc(maxquerylength+MAXLINE+1, sizeof(char));
+ targetlength = maxtargetlength;
+ querylength = maxquerylength;
+ }
+
+ if (tflag && !qflag) {
+ target_sq = (char *) calloc(maxtargetlength+MAXLINE+1,sizeof(char));
+ query_sq = (char *) calloc(strlen(argv[argc-1])+1,sizeof(char));
+ strcpy(query_ac,"command_line");
+ strcpy(query_sq,argv[argc-1]);
+ remove_whitespace(query_sq);
+ targetlength = maxtargetlength;
+ querylength = strlen(argv[argc-1]);
+ }
+
+ if (!tflag && qflag) {
+ target_sq = (char *) calloc(strlen(argv[argc-1])+1,sizeof(char));
+ query_sq = (char *) calloc(maxquerylength+MAXLINE+1, sizeof(char));
+ strcpy(target_ac,"command_line");
+ strcpy(target_sq,argv[argc-1]);
+ remove_whitespace(target_sq);
+ targetlength = strlen(argv[argc-1]);
+ querylength = maxquerylength;
+ }
+
+ if (!tflag && !qflag) {
+ target_sq = (char *) calloc(strlen(argv[argc-2])+1,sizeof(char));
+ query_sq = (char *) calloc(strlen(argv[argc-1])+1,sizeof(char));
+ strcpy(target_ac,"command_line");
+ strcpy(query_ac,"command_line");
+ strcpy(target_sq,argv[argc-2]);
+ remove_whitespace(target_sq);
+ strcpy(query_sq,argv[argc-1]);
+ remove_whitespace(query_sq);
+ targetlength = strlen(argv[argc-2]);
+ querylength = strlen(argv[argc-1]);
+ }
+
+ init_constants();
+ init_energies();
+
+ tableAlloc(targetlength,querylength);
+
+ /* allocate string space */
+ r1 = t1 = (char *) calloc(2*max(targetlength,querylength), sizeof(char));
+ r2 = t2 = (char *) calloc(2*max(targetlength,querylength), sizeof(char));
+ r3 = t3 = (char *) calloc(2*max(targetlength,querylength), sizeof(char));
+ r4 = t4 = (char *) calloc(2*max(targetlength,querylength), sizeof(char));
+
+ x = (char *) calloc(targetlength+2, sizeof(char));
+ y = (char *) calloc( querylength+2, sizeof(char));
+
+
+ if (qflag) {
+
+ FILE *query = fopen( query_fn,"r");
+ if (query==NULL) {
+ printf("Error: Could not open query file. Aborting.\n");
+ exit(2);
+ }
+
+ while (!end(query)) {
+
+ nextAC(query,query_ac);
+ nextSQ(query,query_sq,maxquerylength);
+
+ remove_whitespace(query_sq);
+
+ n = strlen(query_sq);
+
+ if (!dflag) {
+ // estimate evd parameters from maximal duplex energy
+ mde = maximal_duplex_energy(query_sq);
+ xi = xi_slope * mde + xi_intercept;
+ theta = theta_slope * mde + theta_intercept;
+ }
+
+ if (fflag) {
+ helix_start = n - fflag_end;
+ helix_end = n - fflag_start + 1;
+ }
+ else {
+ helix_start = 0;
+ helix_end = 0;
+ }
+
+ if (n > maxquerylength) {
+ printf("query too long: %s\n", query_ac);
+ }
+ else {
+
+ y[0]=' ';
+ for (i=0;i<=n-1;i++) y[i+1] = query_sq[n-i-1];
+ y[n+1]=0;
+ convert_y();
+
+ if (tflag) {
+ FILE *target = fopen(target_fn,"r");
+ if (target==NULL) {
+ printf("Error: Could not open target file. Aborting.\n");
+ exit(2);
+ }
+
+ while (!end(target)) {
+
+ nextAC(target,target_ac);
+ nextSQ(target,target_sq,maxtargetlength);
+
+ remove_whitespace(target_sq);
+
+ m = strlen(target_sq);
+
+ if (m > maxtargetlength) {
+ printf("target too long: %s\n", target_ac);
+ }
+ else {
+ strcpy(x, " ");
+ strcat(x, target_sq);
+ convert_x();
+
+ mainloop(bflag, hit_number,eflag,energy_cutoff,pflag,pvalue_cutoff,cflag,target_ac,target_sq,query_ac,query_sq,gflag,plot_format,xi,theta);
+ }
+
+ }
+
+ fclose(target);
+ }
+ else {
+ m = strlen(target_sq);
+
+ strcpy(x, " ");
+ strcat(x, target_sq);
+ convert_x();
+
+ mainloop(bflag, hit_number,eflag,energy_cutoff,pflag,pvalue_cutoff,cflag,target_ac,target_sq,query_ac,query_sq,gflag,plot_format,xi,theta);
+ }
+ }
+ }
+
+ fclose(query);
+ }
+ else { /* !qflag */
+ n = strlen(query_sq);
+
+ if (!dflag) {
+ // estimate evd parameters from maximal duplex energy
+ mde = maximal_duplex_energy(query_sq);
+ xi = xi_slope * mde + xi_intercept;
+ theta = theta_slope * mde + theta_intercept;
+ }
+
+ if (fflag) {
+ helix_start = n - fflag_end;
+ helix_end = n - fflag_start + 1;
+ }
+ else {
+ helix_start = 0;
+ helix_end = 0;
+ }
+
+
+ y[0]=' ';
+ for (i=0;i<=n-1;i++) y[i+1] = query_sq[n-i-1];
+ y[n+1]=0;
+ convert_y();
+
+ if (tflag) { /* !qflag && tflag */
+ FILE *target = fopen(target_fn,"r");
+
+ while (!end(target)) {
+
+ nextAC(target,target_ac);
+ nextSQ(target,target_sq,maxtargetlength);
+
+ remove_whitespace(target_sq);
+
+ m = strlen(target_sq);
+
+ if (m > maxtargetlength) {
+ printf("target too long: %s\n", target_ac);
+ }
+ else {
+ strcpy(x, " ");
+ strcat(x, target_sq);
+ convert_x();
+
+ mainloop(bflag,hit_number,eflag,energy_cutoff,pflag,pvalue_cutoff,cflag,target_ac,target_sq,query_ac,query_sq,gflag,plot_format,xi,theta);
+ }
+
+ }
+
+ fclose(target);
+ }
+ else { /* !qflag && !tflag */
+ m = strlen(target_sq);
+
+ strcpy(x, " ");
+ strcat(x, target_sq);
+ convert_x();
+
+ mainloop(bflag, hit_number,eflag,energy_cutoff,pflag,pvalue_cutoff,cflag,target_ac,target_sq,query_ac,query_sq,gflag,plot_format,xi,theta);
+ }
+ }
+
+
+ exit(0);
+}
+
+
+
+float maximal_duplex_energy(char *seq_arg)
+{
+ int seq_len = strlen(seq_arg);
+ char *seq = (char *) calloc(seq_len+1, sizeof(char));
+ char *rc = (char *) calloc(seq_len+1, sizeof(char));
+ int i;
+ char letter, compl_letter;
+ float mde;
+ char c;
+
+ // convert sequence:
+ for (i=0; i<seq_len; i++) {
+ c=seq_arg[i];
+ if (c=='a' || c=='A') seq[i]=A;
+ else if (c=='c' || c=='C') seq[i]=C;
+ else if (c=='g' || c=='G') seq[i]=G;
+ else if (c=='u' || c=='U') seq[i]=U;
+ else if (c=='t' || c=='T') seq[i]=U;
+ else seq[i]=N;
+ }
+
+ // make reverse complement:
+ for (i=0; i<seq_len; i++) {
+ c = seq[seq_len-i-1];
+ if (c==A) rc[i]=U;
+ else if (c==C) rc[i]=G;
+ else if (c==G) rc[i]=C;
+ else if (c==U) rc[i]=A;
+ else rc[i]=N;
+ }
+ rc[seq_len] = '\0';
+
+
+ // sum up stacked pair energies:
+ mde = 0;
+ for (i=0; i<seq_len-1; i++)
+ mde += stack_dg_ar[rc[seq_len-i-1]][rc[seq_len-(i+1)-1]][seq[i+1]][seq[i]];
+
+ free(seq);
+ free(rc);
+
+ return mde;
+}
+
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