[med-svn] [libfreecontact-perl] 02/46: Imported Upstream version 0.01
Laszlo Kajan
lkajan at alioth.debian.org
Thu Sep 19 15:54:58 UTC 2013
This is an automated email from the git hooks/post-receive script.
lkajan pushed a commit to branch master
in repository libfreecontact-perl.
commit 8a864574501daf7266ffdc1b90befc3b5537405c
Author: Laszlo Kajan <lkajan at debian.org>
Date: Fri May 10 17:53:58 2013 +0200
Imported Upstream version 0.01
---
Changes | 6 +
FreeContact-0.01.tar.gz | Bin 0 -> 472 bytes
FreeContact.c | 410 +++++++++++++++++++
FreeContact.o | Bin 0 -> 1176456 bytes
FreeContact.xs | 51 +++
FreeContact.xsp | 73 ++++
MANIFEST | 19 +
MANIFEST.SKIP | 40 ++
Makefile.PL | 28 ++
README | 30 ++
examples/demo_1000.aln | 1000 +++++++++++++++++++++++++++++++++++++++++++++++
lib/FreeContact.pm | 195 +++++++++
perlobject.map | 106 +++++
t/01FreeContact.t | 20 +
t/02test.t | 41 ++
typemap | 93 +++++
typemap.xsp | 18 +
17 files changed, 2130 insertions(+)
diff --git a/Changes b/Changes
new file mode 100644
index 0000000..dbe1443
--- /dev/null
+++ b/Changes
@@ -0,0 +1,6 @@
+Revision history for Perl extension FreeContact.
+
+0.01 Mon Apr 29 14:09:10 2013
+ - original version; created by h2xs 1.23 with options
+ -n FreeContact -b 5.10.1 --omit-constant --skip-ppport /usr/include/freecontact.h -lfreecontact
+
diff --git a/FreeContact-0.01.tar.gz b/FreeContact-0.01.tar.gz
new file mode 100644
index 0000000..33229e2
Binary files /dev/null and b/FreeContact-0.01.tar.gz differ
diff --git a/FreeContact.bs b/FreeContact.bs
new file mode 100644
index 0000000..e69de29
diff --git a/FreeContact.c b/FreeContact.c
new file mode 100644
index 0000000..98f3c4f
--- /dev/null
+++ b/FreeContact.c
@@ -0,0 +1,410 @@
+/*
+ * This file was generated automatically by ExtUtils::ParseXS version 2.2206 from the
+ * contents of FreeContact.xs. Do not edit this file, edit FreeContact.xs instead.
+ *
+ * ANY CHANGES MADE HERE WILL BE LOST!
+ *
+ */
+
+#line 1 "FreeContact.xs"
+/* Copyright (C) 2013 by Laszlo Kajan, Technical University of Munich, Germany
+
+ This library is free software; you can redistribute it and/or modify
+ it under the same terms as Perl itself, either Perl version 5.10.1 or,
+ at your option, any later version of Perl 5 you may have available.
+*/
+#include <freecontact.h>
+
+#ifdef __cplusplus
+extern "C" {
+#include "EXTERN.h"
+#include "perl.h"
+#include "XSUB.h"
+}
+#endif
+
+using namespace freecontact;
+typedef freecontact::predictor::cont_res_t cont_res_t;
+typedef freecontact::predictor::time_res_t time_res_t;
+
+#define _XPUSHS_GET_PS(__ps) \
+ XPUSHs(sv_2mortal(newSVpvn("clustpc", 7)));\
+ XPUSHs(sv_2mortal(newSVnv((__ps).clustpc)));\
+ XPUSHs(sv_2mortal(newSVpvn("sparsity", 8)));\
+ XPUSHs(sv_2mortal(newSVnv((__ps).sparsity)));\
+ XPUSHs(sv_2mortal(newSVpvn("gapth", 5)));\
+ XPUSHs(sv_2mortal(newSVnv((__ps).gapth)));\
+ XPUSHs(sv_2mortal(newSVpvn("mincontsep", 10)));\
+ XPUSHs(sv_2mortal(newSVuv((__ps).mincontsep)));\
+\
+ XPUSHs(sv_2mortal(newSVpvn("pseudocnt", 9)));\
+ XPUSHs(sv_2mortal(newSVnv((__ps).pseudocnt)));\
+ XPUSHs(sv_2mortal(newSVpvn("pscnt_weight", 12)));\
+ XPUSHs(sv_2mortal(newSVnv((__ps).pscnt_weight)));\
+ XPUSHs(sv_2mortal(newSVpvn("estimate_ivcov", 14)));\
+ XPUSHs(sv_2mortal(newSViv((__ps).estimate_ivcov)));\
+ XPUSHs(sv_2mortal(newSVpvn("shrink_lambda", 13)));\
+ XPUSHs(sv_2mortal(newSVnv((__ps).shrink_lambda)));\
+\
+ XPUSHs(sv_2mortal(newSVpvn("cov20", 5)));\
+ XPUSHs(sv_2mortal(newSViv((__ps).cov20)));\
+ XPUSHs(sv_2mortal(newSVpvn("gap_incovm", 10)));\
+ XPUSHs(sv_2mortal(newSViv((__ps).gap_incovm)));\
+ XPUSHs(sv_2mortal(newSVpvn("veczw", 5)));\
+ XPUSHs(sv_2mortal(newSViv((__ps).veczw)));\
+ XPUSHs(sv_2mortal(newSVpvn("rho", 3)));\
+ XPUSHs(sv_2mortal(newSVnv((__ps).rho)));
+
+#line 59 "FreeContact.c"
+#ifndef PERL_UNUSED_VAR
+# define PERL_UNUSED_VAR(var) if (0) var = var
+#endif
+
+#ifndef PERL_ARGS_ASSERT_CROAK_XS_USAGE
+#define PERL_ARGS_ASSERT_CROAK_XS_USAGE assert(cv); assert(params)
+
+/* prototype to pass -Wmissing-prototypes */
+STATIC void
+S_croak_xs_usage(pTHX_ const CV *const cv, const char *const params);
+
+STATIC void
+S_croak_xs_usage(pTHX_ const CV *const cv, const char *const params)
+{
+ const GV *const gv = CvGV(cv);
+
+ PERL_ARGS_ASSERT_CROAK_XS_USAGE;
+
+ if (gv) {
+ const char *const gvname = GvNAME(gv);
+ const HV *const stash = GvSTASH(gv);
+ const char *const hvname = stash ? HvNAME(stash) : NULL;
+
+ if (hvname)
+ Perl_croak(aTHX_ "Usage: %s::%s(%s)", hvname, gvname, params);
+ else
+ Perl_croak(aTHX_ "Usage: %s(%s)", gvname, params);
+ } else {
+ /* Pants. I don't think that it should be possible to get here. */
+ Perl_croak(aTHX_ "Usage: CODE(0x%"UVxf")(%s)", PTR2UV(cv), params);
+ }
+}
+#undef PERL_ARGS_ASSERT_CROAK_XS_USAGE
+
+#ifdef PERL_IMPLICIT_CONTEXT
+#define croak_xs_usage(a,b) S_croak_xs_usage(aTHX_ a,b)
+#else
+#define croak_xs_usage S_croak_xs_usage
+#endif
+
+#endif
+
+/* NOTE: the prototype of newXSproto() is different in versions of perls,
+ * so we define a portable version of newXSproto()
+ */
+#ifdef newXS_flags
+#define newXSproto_portable(name, c_impl, file, proto) newXS_flags(name, c_impl, file, proto, 0)
+#else
+#define newXSproto_portable(name, c_impl, file, proto) (PL_Sv=(SV*)newXS(name, c_impl, file), sv_setpv(PL_Sv, proto), (CV*)PL_Sv)
+#endif /* !defined(newXS_flags) */
+
+#line 111 "FreeContact.c"
+
+/* INCLUDE_COMMAND: Including output of '/usr/bin/perl -MExtUtils::XSpp::Cmd -e xspp -- --typemap=typemap.xsp FreeContact.xsp' from 'FreeContact.xs' */
+
+#include <exception>
+
+
+XS(XS_FreeContact_get_ps_evfold); /* prototype to pass -Wmissing-prototypes */
+XS(XS_FreeContact_get_ps_evfold)
+{
+#ifdef dVAR
+ dVAR; dXSARGS;
+#else
+ dXSARGS;
+#endif
+ if (items != 0)
+ croak_xs_usage(cv, "");
+ PERL_UNUSED_VAR(ax); /* -Wall */
+ SP -= items;
+ {
+#line 12 "/usr/bin/perl -MExtUtils::XSpp::Cmd -e xspp -- --typemap=typemap.xsp FreeContact.xsp"
+ _XPUSHS_GET_PS(ps_evfold);
+#line 133 "FreeContact.c"
+ PUTBACK;
+ return;
+ }
+}
+
+
+XS(XS_FreeContact_get_ps_psicov); /* prototype to pass -Wmissing-prototypes */
+XS(XS_FreeContact_get_ps_psicov)
+{
+#ifdef dVAR
+ dVAR; dXSARGS;
+#else
+ dXSARGS;
+#endif
+ if (items != 0)
+ croak_xs_usage(cv, "");
+ PERL_UNUSED_VAR(ax); /* -Wall */
+ SP -= items;
+ {
+#line 17 "/usr/bin/perl -MExtUtils::XSpp::Cmd -e xspp -- --typemap=typemap.xsp FreeContact.xsp"
+ _XPUSHS_GET_PS(ps_psicov);
+#line 155 "FreeContact.c"
+ PUTBACK;
+ return;
+ }
+}
+
+
+XS(XS_FreeContact__Predictor_new); /* prototype to pass -Wmissing-prototypes */
+XS(XS_FreeContact__Predictor_new)
+{
+#ifdef dVAR
+ dVAR; dXSARGS;
+#else
+ dXSARGS;
+#endif
+ if (items < 1 || items > 2)
+ croak_xs_usage(cv, "CLASS, __dbg = false");
+ {
+ bool __dbg;
+ char * CLASS = (char *)SvPV_nolen(ST(0));
+ predictor * RETVAL;
+
+ if (items < 2)
+ __dbg = false;
+ else {
+ __dbg = (bool)SvTRUE(ST(1));
+ }
+#line 28 "/usr/bin/perl -MExtUtils::XSpp::Cmd -e xspp -- --typemap=typemap.xsp FreeContact.xsp"
+ try {
+ RETVAL = new predictor( __dbg );
+ }
+ catch (std::exception& e) {
+ croak("Caught C++ exception of type or derived from 'std::exception': %s", e.what());
+ }
+ catch (...) {
+ croak("Caught C++ exception of unknown type");
+ }
+#line 192 "FreeContact.c"
+ ST(0) = sv_newmortal();
+ sv_setref_pv( ST(0), CLASS, (void*)RETVAL );
+
+ }
+ XSRETURN(1);
+}
+
+
+XS(XS_FreeContact__Predictor_DESTROY); /* prototype to pass -Wmissing-prototypes */
+XS(XS_FreeContact__Predictor_DESTROY)
+{
+#ifdef dVAR
+ dVAR; dXSARGS;
+#else
+ dXSARGS;
+#endif
+ if (items != 1)
+ croak_xs_usage(cv, "THIS");
+ {
+ predictor * THIS;
+
+ if( sv_isobject(ST(0)) && (SvTYPE(SvRV(ST(0))) == SVt_PVMG) )
+ THIS = (predictor *)SvIV((SV*)SvRV( ST(0) ));
+ else{
+ warn( "FreeContact::Predictor::DESTROY() -- THIS is not a blessed SV reference" );
+ XSRETURN_UNDEF;
+ };
+#line 42 "/usr/bin/perl -MExtUtils::XSpp::Cmd -e xspp -- --typemap=typemap.xsp FreeContact.xsp"
+ try {
+ delete THIS;
+ }
+ catch (std::exception& e) {
+ croak("Caught C++ exception of type or derived from 'std::exception': %s", e.what());
+ }
+ catch (...) {
+ croak("Caught C++ exception of unknown type");
+ }
+#line 230 "FreeContact.c"
+ }
+ XSRETURN_EMPTY;
+}
+
+
+XS(XS_FreeContact__Predictor__run); /* prototype to pass -Wmissing-prototypes */
+XS(XS_FreeContact__Predictor__run)
+{
+#ifdef dVAR
+ dVAR; dXSARGS;
+#else
+ dXSARGS;
+#endif
+ if (items < 14 || items > 16)
+ croak_xs_usage(cv, "THIS, __ali, __cp, __spar, __gapth, __mincontsep, __pseudocnt, __pscnt_weight, __estimate_ivcov, __shrink_lambda, __cov20, __gap_incovm, __vecw, __rho, __num_threads = 0, __timing = NULL");
+ {
+ ali_t __ali;
+ double __cp = (double)SvNV(ST(2));
+ double __spar = (double)SvNV(ST(3));
+ double __gapth = (double)SvNV(ST(4));
+ U16 __mincontsep = (unsigned short)SvUV(ST(5));
+ double __pseudocnt = (double)SvNV(ST(6));
+ double __pscnt_weight = (double)SvNV(ST(7));
+ bool __estimate_ivcov = (bool)SvTRUE(ST(8));
+ double __shrink_lambda = (double)SvNV(ST(9));
+ bool __cov20 = (bool)SvTRUE(ST(10));
+ bool __gap_incovm = (bool)SvTRUE(ST(11));
+ bool __vecw = (bool)SvTRUE(ST(12));
+ double __rho = (double)SvNV(ST(13));
+ int __num_threads;
+ time_res_t* __timing;
+#line 73 "/usr/bin/perl -MExtUtils::XSpp::Cmd -e xspp -- --typemap=typemap.xsp FreeContact.xsp"
+ time_res_t timing;
+#line 264 "FreeContact.c"
+ predictor * THIS;
+ cont_res_t RETVAL;
+
+ {
+ if(SvROK(ST(1)) && SvTYPE(SvRV(ST(1))) == SVt_PVAV)
+ {
+ // ST(1) is an array reference to strings - the sequences in the alignment
+ AV *arr = (AV*)SvRV(ST(1));
+ I32 seqcnt = av_len(arr)+1; // av_len returns highest index
+ if(seqcnt > 0)
+ {
+ SV** lineptr = av_fetch(arr, 0, false);
+ if(lineptr != NULL && SvPOK(*lineptr))
+ {
+ STRLEN alilen = SvCUR(*lineptr);
+ if(alilen <= 0xFFFF)
+ {
+ __ali = ali_t(alilen);
+
+ for(I32 k = 0; k < seqcnt; ++k)
+ {
+ SV** lineptr = av_fetch(arr, k, false);
+ if(lineptr != NULL && SvPOK(*lineptr))
+ {
+ STRLEN alilen = SvCUR(*lineptr);
+ if(alilen <= 0xFFFF)
+ {
+ const char *al = SvPVbyte(*lineptr, alilen);
+ __ali.push(std::string(al, alilen));
+ }
+ }
+ }
+ }
+ else croak("FreeContact::Predictor::_run() -- __ali->[0] is too long");
+ }
+ else croak("FreeContact::Predictor::_run() -- __ali->[0] is not a character string");
+ }
+ }
+ else croak("FreeContact::Predictor::_run() -- __ali is not an AV reference");
+ };
+
+ if (items < 15)
+ __num_threads = 0;
+ else {
+ __num_threads = (int)SvIV(ST(14));
+ }
+
+ if (items < 16)
+ __timing = NULL;
+ else {
+ __timing = (time_res_t*)~NULL;
+ }
+
+ if( sv_isobject(ST(0)) && (SvTYPE(SvRV(ST(0))) == SVt_PVMG) )
+ THIS = (predictor *)SvIV((SV*)SvRV( ST(0) ));
+ else{
+ warn( "FreeContact::Predictor::_run() -- THIS is not a blessed SV reference" );
+ XSRETURN_UNDEF;
+ };
+#line 75 "/usr/bin/perl -MExtUtils::XSpp::Cmd -e xspp -- --typemap=typemap.xsp FreeContact.xsp"
+ try {
+ if(__timing) __timing = &timing;
+ RETVAL = THIS->run( __ali, __cp, __spar, __gapth, __mincontsep, __pseudocnt, __pscnt_weight, __estimate_ivcov, __shrink_lambda, __cov20, __gap_incovm, __vecw, __rho, __num_threads, __timing );
+ }
+ catch (std::exception& e) {
+ croak("Caught C++ exception of type or derived from 'std::exception': %s", e.what());
+ }
+ catch (...) {
+ croak("Caught C++ exception of unknown type");
+ }
+#line 335 "FreeContact.c"
+ if(__timing && SvROK(ST(15)) && SvTYPE(SvRV(ST(15))) == SVt_PVHV)
+ {
+ // return { 'key' => 0.0, ... }
+ HV* res = (HV*)SvRV(ST(15));
+ for(time_res_t::const_iterator tr_i = __timing->begin(), tr_e = __timing->end(); tr_i != tr_e; ++tr_i)
+ hv_store(res, tr_i->first.c_str(), tr_i->first.length(), newSVnv(tr_i->second), 0);
+ }
+
+ SvSETMAGIC(ST(15));
+ ST(0) = sv_newmortal();
+ if(RETVAL.empty()) ST(0) = &PL_sv_undef;
+ else
+ {
+
+ // return { 'l1norm' => [ [ 0, 1, 45.786 ], [ 0, 2, 7.993 ], ... ], ... }
+ HV* res = (HV*)sv_2mortal((SV*)newHV());
+ for(cont_res_t::const_iterator cr_i = RETVAL.begin(), cr_e = RETVAL.end(); cr_i != cr_e; ++cr_i)
+ {
+ AV* contacts = (AV*)sv_2mortal((SV*)newAV()); av_extend(contacts, cr_i->second.size()-1); // extend to index
+
+ for(std::vector<contact_t>::const_iterator ct_i = cr_i->second.begin(), ct_e = cr_i->second.end(); ct_i != ct_e; ++ct_i)
+ {
+ AV* ijscore = (AV*)sv_2mortal((SV*)newAV()); av_extend(ijscore, 2); // extend to index
+
+ av_push(ijscore, newSVuv(ct_i->i));
+ av_push(ijscore, newSVuv(ct_i->j));
+ av_push(ijscore, newSVnv(ct_i->score));
+ //
+ av_push(contacts, newRV((SV*)ijscore));
+ }
+
+ hv_store(res, cr_i->first.c_str(), cr_i->first.length(), newRV((SV*)contacts), 0);
+ }
+
+ sv_setsv(ST(0), newRV((SV*)res));
+ }
+ }
+ XSRETURN(1);
+}
+
+
+/* INCLUDE: Returning to 'FreeContact.xs' from '/usr/bin/perl -MExtUtils::XSpp::Cmd -e xspp -- --typemap=typemap.xsp FreeContact.xsp' */
+
+#ifdef __cplusplus
+extern "C"
+#endif
+XS(boot_FreeContact); /* prototype to pass -Wmissing-prototypes */
+XS(boot_FreeContact)
+{
+#ifdef dVAR
+ dVAR; dXSARGS;
+#else
+ dXSARGS;
+#endif
+#if (PERL_REVISION == 5 && PERL_VERSION < 9)
+ char* file = __FILE__;
+#else
+ const char* file = __FILE__;
+#endif
+
+ PERL_UNUSED_VAR(cv); /* -W */
+ PERL_UNUSED_VAR(items); /* -W */
+ XS_VERSION_BOOTCHECK ;
+
+ newXS("FreeContact::get_ps_evfold", XS_FreeContact_get_ps_evfold, file);
+ newXS("FreeContact::get_ps_psicov", XS_FreeContact_get_ps_psicov, file);
+ newXS("FreeContact::Predictor::new", XS_FreeContact__Predictor_new, file);
+ newXS("FreeContact::Predictor::DESTROY", XS_FreeContact__Predictor_DESTROY, file);
+ newXS("FreeContact::Predictor::_run", XS_FreeContact__Predictor__run, file);
+#if (PERL_REVISION == 5 && PERL_VERSION >= 9)
+ if (PL_unitcheckav)
+ call_list(PL_scopestack_ix, PL_unitcheckav);
+#endif
+ XSRETURN_YES;
+}
+
diff --git a/FreeContact.o b/FreeContact.o
new file mode 100644
index 0000000..1867aa7
Binary files /dev/null and b/FreeContact.o differ
diff --git a/FreeContact.xs b/FreeContact.xs
new file mode 100644
index 0000000..fcaa6df
--- /dev/null
+++ b/FreeContact.xs
@@ -0,0 +1,51 @@
+/* Copyright (C) 2013 by Laszlo Kajan, Technical University of Munich, Germany
+
+ This library is free software; you can redistribute it and/or modify
+ it under the same terms as Perl itself, either Perl version 5.10.1 or,
+ at your option, any later version of Perl 5 you may have available.
+*/
+#include <freecontact.h>
+
+#ifdef __cplusplus
+extern "C" {
+#include "EXTERN.h"
+#include "perl.h"
+#include "XSUB.h"
+}
+#endif
+
+using namespace freecontact;
+typedef freecontact::predictor::cont_res_t cont_res_t;
+typedef freecontact::predictor::time_res_t time_res_t;
+
+#define _XPUSHS_GET_PS(__ps) \
+ XPUSHs(sv_2mortal(newSVpvn("clustpc", 7)));\
+ XPUSHs(sv_2mortal(newSVnv((__ps).clustpc)));\
+ XPUSHs(sv_2mortal(newSVpvn("sparsity", 8)));\
+ XPUSHs(sv_2mortal(newSVnv((__ps).sparsity)));\
+ XPUSHs(sv_2mortal(newSVpvn("gapth", 5)));\
+ XPUSHs(sv_2mortal(newSVnv((__ps).gapth)));\
+ XPUSHs(sv_2mortal(newSVpvn("mincontsep", 10)));\
+ XPUSHs(sv_2mortal(newSVuv((__ps).mincontsep)));\
+\
+ XPUSHs(sv_2mortal(newSVpvn("pseudocnt", 9)));\
+ XPUSHs(sv_2mortal(newSVnv((__ps).pseudocnt)));\
+ XPUSHs(sv_2mortal(newSVpvn("pscnt_weight", 12)));\
+ XPUSHs(sv_2mortal(newSVnv((__ps).pscnt_weight)));\
+ XPUSHs(sv_2mortal(newSVpvn("estimate_ivcov", 14)));\
+ XPUSHs(sv_2mortal(newSViv((__ps).estimate_ivcov)));\
+ XPUSHs(sv_2mortal(newSVpvn("shrink_lambda", 13)));\
+ XPUSHs(sv_2mortal(newSVnv((__ps).shrink_lambda)));\
+\
+ XPUSHs(sv_2mortal(newSVpvn("cov20", 5)));\
+ XPUSHs(sv_2mortal(newSViv((__ps).cov20)));\
+ XPUSHs(sv_2mortal(newSVpvn("gap_incovm", 10)));\
+ XPUSHs(sv_2mortal(newSViv((__ps).gap_incovm)));\
+ XPUSHs(sv_2mortal(newSVpvn("veczw", 5)));\
+ XPUSHs(sv_2mortal(newSViv((__ps).veczw)));\
+ XPUSHs(sv_2mortal(newSVpvn("rho", 3)));\
+ XPUSHs(sv_2mortal(newSVnv((__ps).rho)));
+
+MODULE = FreeContact PACKAGE = FreeContact
+
+INCLUDE_COMMAND: $^X -MExtUtils::XSpp::Cmd -e xspp -- --typemap=typemap.xsp FreeContact.xsp
diff --git a/FreeContact.xsp b/FreeContact.xsp
new file mode 100644
index 0000000..5aa31d0
--- /dev/null
+++ b/FreeContact.xsp
@@ -0,0 +1,73 @@
+/* Copyright (C) 2013 by Laszlo Kajan, Technical University of Munich, Germany
+
+ This library is free software; you can redistribute it and/or modify
+ it under the same terms as Perl itself, either Perl version 5.10.1 or,
+ at your option, any later version of Perl 5 you may have available.
+*/
+%module{FreeContact};
+
+%{
+MODULE=FreeContact PACKAGE=FreeContact
+
+void
+get_ps_evfold()
+ PPCODE:
+ _XPUSHS_GET_PS(ps_evfold);
+
+void
+get_ps_psicov()
+ PPCODE:
+ _XPUSHS_GET_PS(ps_psicov);
+%}
+
+// Example: /usr/share/doc/libextutils-xspp-perl/examples/Object-WithIntAndString/Object-WithIntAndString.xsp
+%name{FreeContact::Predictor} class predictor
+{
+ predictor(bool __dbg = false);
+ ~predictor();
+
+// lkajan: I apparently can not use this to add an INIT: block to the XS
+/* cont_res_t _run( ali_t& __ali, double __cp, double __spar, double __gapth, U16 __mincontsep,
+ double __pseudocnt, double __pscnt_weight, bool __estimate_ivcov, double __shrink_lambda,
+ bool __cov20, bool __gap_incovm, bool __vecw, double __rho,
+ int __num_threads = 0, time_res_t *__timing = NULL
+ );*/
+};
+
+%{
+cont_res_t
+predictor::_run( __ali, __cp, __spar, __gapth, __mincontsep, __pseudocnt, __pscnt_weight, __estimate_ivcov, __shrink_lambda, __cov20, __gap_incovm, __vecw, __rho, __num_threads = 0, __timing = NULL )
+ ali_t& __ali
+ double __cp
+ double __spar
+ double __gapth
+ U16 __mincontsep
+ double __pseudocnt
+ double __pscnt_weight
+ bool __estimate_ivcov
+ double __shrink_lambda
+ bool __cov20
+ bool __gap_incovm
+ bool __vecw
+ double __rho
+ int __num_threads
+ time_res_t* __timing
+ PREINIT:
+ time_res_t timing;
+ CODE:
+ try {
+ if(__timing) __timing = &timing;
+ RETVAL = THIS->run( __ali, __cp, __spar, __gapth, __mincontsep, __pseudocnt, __pscnt_weight, __estimate_ivcov, __shrink_lambda, __cov20, __gap_incovm, __vecw, __rho, __num_threads, __timing );
+ }
+ catch (std::exception& e) {
+ croak("Caught C++ exception of type or derived from 'std::exception': %s", e.what());
+ }
+ catch (...) {
+ croak("Caught C++ exception of unknown type");
+ }
+ OUTPUT:
+ __timing
+ RETVAL
+%}
+
+// vim:et:ts=4:ai:syntax=cpp:
diff --git a/MANIFEST b/MANIFEST
new file mode 100644
index 0000000..8a20b0c
--- /dev/null
+++ b/MANIFEST
@@ -0,0 +1,19 @@
+Changes
+examples/demo_1000.aln
+FreeContact-0.01.tar.gz
+FreeContact.bs
+FreeContact.c
+FreeContact.o
+FreeContact.xs
+FreeContact.xsp
+lib/FreeContact.pm
+Makefile.PL
+MANIFEST This list of files
+MANIFEST.SKIP
+perlobject.map
+README
+t/01FreeContact.t
+t/02test.t
+typemap
+typemap.xsp
+META.yml Module meta-data (added by MakeMaker)
diff --git a/MANIFEST.SKIP b/MANIFEST.SKIP
new file mode 100644
index 0000000..8d3a0b8
--- /dev/null
+++ b/MANIFEST.SKIP
@@ -0,0 +1,40 @@
+
+#!start included /usr/share/perl/5.10/ExtUtils/MANIFEST.SKIP
+# Avoid version control files.
+\bRCS\b
+\bCVS\b
+\bSCCS\b
+,v$
+\B\.svn\b
+\B\.git\b
+\B\.gitignore\b
+\b_darcs\b
+
+# Avoid Makemaker generated and utility files.
+\bMANIFEST\.bak
+\bMakefile$
+\bblib/
+\bMakeMaker-\d
+\bpm_to_blib\.ts$
+\bpm_to_blib$
+\bblibdirs\.ts$ # 6.18 through 6.25 generated this
+
+# Avoid Module::Build generated and utility files.
+\bBuild$
+\b_build/
+
+# Avoid temp and backup files.
+~$
+\.old$
+\#$
+\b\.#
+\.bak$
+
+# Avoid Devel::Cover files.
+\bcover_db\b
+#!end included /usr/share/perl/5.10/ExtUtils/MANIFEST.SKIP
+
+.swp$
+.vim$
+debian
+zergtest
diff --git a/Makefile.PL b/Makefile.PL
new file mode 100644
index 0000000..ecae2ac
--- /dev/null
+++ b/Makefile.PL
@@ -0,0 +1,28 @@
+#!/usr/bin/perl
+use 5.010001;
+use ExtUtils::MakeMaker;
+# See lib/ExtUtils/MakeMaker.pm for details of how to influence
+# the contents of the Makefile that is written.
+
+# Example: /usr/share/doc/libextutils-xspp-perl/examples/Object-WithIntAndString/Makefile.PL
+my $CC = 'g++';
+
+WriteMakefile(
+ NAME => 'FreeContact',
+ VERSION_FROM => 'lib/FreeContact.pm', # finds $VERSION
+ PREREQ_PM => {
+ 'ExtUtils::XSpp' => '0.01',
+ },
+ ($] >= 5.005 ? ## Add these new keywords supported since 5.005
+ (ABSTRACT_FROM => 'lib/FreeContact.pm',
+ AUTHOR => 'Laszlo Kajan <lkajan at rostlab.org>') : ()),
+ LIBS => ['-lfreecontact '],
+ DEFINE => '', # e.g., '-DHAVE_SOMETHING'
+ INC => '-I.',
+ OBJECT => '$(O_FILES)',
+ XSOPT => '-C++ -hiertype -noprototypes', # man xsubpp
+ TYPEMAPS => ['perlobject.map', 'typemap'],
+ CC => $CC,
+ LD => '$(CC)',
+);
+# vim:et:ts=4:ai:
diff --git a/README b/README
new file mode 100644
index 0000000..21d0576
--- /dev/null
+++ b/README
@@ -0,0 +1,30 @@
+FreeContact version 0.01
+========================
+
+This package contains Perl binding for FreeContact, a fast C/C++ library for
+protein contact prediction.
+
+INSTALLATION
+
+To install this module type the following:
+
+ perl Makefile.PL
+ make
+ make test
+ make install
+
+DEPENDENCIES
+
+This module requires these other modules and libraries:
+
+ blah blah blah
+
+COPYRIGHT AND LICENCE
+
+Put the correct copyright and licence information here.
+
+Copyright (C) 2013 by Laszlo Kajan
+
+This library is free software; you can redistribute it and/or modify
+it under the same terms as Perl itself, either Perl version 5.10.1 or,
+at your option, any later version of Perl 5 you may have available.
diff --git a/examples/demo_1000.aln b/examples/demo_1000.aln
new file mode 100644
index 0000000..348b6f0
--- /dev/null
+++ b/examples/demo_1000.aln
@@ -0,0 +1,1000 @@
+ADKELKFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGVDALNKLQAGGYGFVISDWNMPNMDGLELLKTIRAAMSALPVLMVTAEAKKENIIAAAQAGASGYVVKPFTAATLEEKLNKIFEKLGM
+-----TVLIAEDEMIEREFLVNLLNRLDFHVVAEAGDGQTAVELAFLHRPDVAFLDIRMPLLDGLAAAGKIKKALPQTFIVLNSAFAEFKYAQQGIDCGVDAYLLKPSSESEIFSLLRS-------
+-----TVLIAEDDVSVRGLVDSLLRKYGYQ-VVLAVDGGDCVRKFLEHRIDLILMDVIMPGKNGREAFDEIRRIDPSVRVLYSSGYTADFMKNRGVFEESVDLIMKPVQPMALLQKVREVLDRKG-
+-----TVLIAEDDLHVLDLVSSILQQYGYS-IIPAANGLEAVQKFKENQIKLVLMDIIMPVMNGKEAAECIRELRHDARILFTSGYTADIIRSRSDLDEGAELVMKPVKPPVLLQKIREMLDR---
+-----TVLIAEDDGDIIEILSLYLGGSGYE-VRAARNGADALEILRREQVAVALVDIMMPKMNGYDLIKAARAE-SQVPIIIISARAEAADKIIGLDAGADGYITKPFDPLEVTAYIRAVLRRG--
+-----TVLIAEDDAALLEVARRILSRNGYE-VLAASTALDACSIAIEHRIHLLLTDVIMPRMQGRELANRIRAQQPGIRVLYMSGYADPVLTAQGKLDPGVSLLTKPFSERTLLDKVRQVLD----
+-----TVLIADQHPVIAESIKYILETNDFIVIGQVLTGKELFKYLENRAPDVLMIEIDLPQLNGIHALRQIKQQYPHIKILVFSCHPEEMYALSAIKAGAAGYISKTNPADIVYKAIKQVTR----
+-----TVLIADDSRFTRNLLKKLLTDNGYQVVAEASDGNNAISLYQEKTPDIVILDLIMPIMNGLDALKSILKFDPEAKVIICSSMGQKSFIIDALQIGAKDFIIKPY-FNELIPALNKLF-----
+-----TVLIADDQPMQRFGSRMLLEQDDMTVVGEAANGNEAVGLVARHRPDVVLMDIRMPGLDGIEATRRIIASGAGTRILIVTTFDLDEYAYDGLRAGASGFLVKDALPEELLAGIRAVA-----
+-----TVLIADDQPMQRFGFRMLLEQDDMTVVGEASNGTEAVRLVDRHHPDVVLMDIRMPGLDGIEATRRIITTGARTRVLIVTTFDLDEYAYDGLRAGASGFLVKDAQPEELLAGIRAVA-----
+-----TVLIADDQPLQRMGFRMLMETPGLSPIGEAEHGAEAVRLAEQLRPDVVLMDIRMPGMDGLEATRRIVAAGGRTRVLIVTTFDLDEYAYEGLRAGASGFLLKDARPEELVAGIHAVA-----
+-----TVLIADDQPLQRLGFRMLLETPGLTPVGEAEHGGEAVRLAAQLRPDVVLMDIRMPGMDGLEATRRIVAAGGRTRVLIVTTFDLDEYAYDGLRAGASGFLLKDARPEELVAGIHAVA-----
+-----TVLIADDQPLQRLGFGMLLQTPGLTAVGEAEHGAEAVRLAAELRPDVVLMDIRMPGMDGLEATRRIVATGGRTRVLIVTTFDLDAYAYEGLRAGASGFLLKDARPEEIVAGIHAVA-----
+-----TVLIADDQPLQRFGSRMLLEQDDMTVVGEAANGSEAVRLAAELHPDVVLMDIRMPGLDGIEATRRITAAGDRTRILIVTTFDLDEYAYAGLRAGASGFLVKDAQPEELLSGIRAVA-----
+-----TVLIADDQPLQRFGFRMLLEQDDMTVVGEAANGAEAARMAAELHPDVVLMDVRMPGLDGIEATRRIVAGGGRSRVLILTTFDLDEYAYSGLRAGASGFLVKDALPEELLSGIRAVA-----
+-----TVLIADDQPLQRFGFRMLLEQDDMTVLGEAANGTEAIRMTAELHPDVVLMDIRMPGLDGIEATRRIVATGDRTRVLILTTFDLDEYAYAGLRAGASGFLVKDVRPEELLSGIRAVA-----
+-----TVLIADDQPLQRFGFRMLLEQDDLTVLGEAANGAEAIRMTAELSPDVVLMDVRMPGLDGIEATRRIVATGDRTRVLILTTFDLDEYAYAGLRAGASGFLVKDAQPEELLSGIRSVA-----
+-----TVLIADDNSDMRAFLKSVLSRY-YN-VVEAVDGQQAYQLAKLNRPDILVSDVMMPGMDGFELLRRLKADTAGMSVILLSARAGSESRIEGLAEGADDYLVKPFEAKELVARVNTHLQ----
+-----TVLIADDNIINIQILNRRLTKFGHK-VLVSRDGQECYNMFAANQTDFILMDLNMPVVDGWASVKMIRDR-PRVPVFAISGMLRRGDEQRYKDVGFDGWMPKPIDMKRLSTYLTGAV-----
+-----TVLIADDEPSFVEALVLGLTREGFE-TIVANDGEEALALSRSHHPDLILLDVMLPRLSGLDVCRTIRQE-SSVPIIMVTARSGELDTVLGLELGADDYVTKPFRMSELVARIRAQMRRT--
+-----TVLIADDDTAIRTVLNQALARAGFA-PRATGNAATLWRWVSQGEGDVVITDVVMPDENAFDLIPRIKKLRPDLPIIVMSAQNTLMTALTATEKGAFEYLPKPFDLNEVVAVISRALSE---
+-----TVLIADDDRTIRTVLTQALTRAGCR-VHATGSLSQLLRWVEEGRGDLVVTDVMMPDGNGIDMIPAIRKARPDLPVIVISAQNTIVTAIRATEAAAFDYLPKPFDLPDLMARAGQALSRR--
+-----TVLIADDDRAIRESLERALQLEGYQ-TRTAADGVETLAAVHSDPVDLLILDVMMPGVDGLGVCRVLRAEGDRTPILMLTARVETSDRVAGLDAGADDYLPKPFELDELLARIRALLRRA--
+-----TVLIADDDPNLRFLLSDMLQRAGFD-VLVAEDGSALLQIAQEQLPDIILVDLMLPGVDGYEAIRQLRNRTAHLPIIIVTARTNPADVVIGFDTGADDYVTKPFNEAELIARIRSLLRRTT-
+-----TVLIADDDPALLTYLQQLLQPWGWQ-LTVCKRGEQFWEILESSQPDLIILDADLPGYNGFELCRALRSDWINQPILILAERYDSELVQQALRYGADDVITKPIASSELVARIYNRLEK---
+-----TVLIADDDKLTREMLKEILVSNGFR-VLLAADGMEAYKEIVASRPQVVLTDKEMPNFDGFQLIKLVKADLKSIPIILISDKTTDDDEARLFELGFFDFMSKPIKAVTLVSRVKRAMS----
+-----TVLHIEESEFFCNIVKNTLVQGNYS-YISADNFNEAYKILQDSDIDIIITSLYAKGGSIENFLKDINYSKKDIPIFVVTSNAIDETKKKLLNLGVTDYILKKDLNEQIIQRIDSIFQS---
+-----TVLFVDDSRTARKAIKYTLLKLGFD-VVEAVDGKDGLEKLEKKHLKLIVSDVEMPKMDGYHFFSKIQERFANIPVIFNSSICDDYSAQKALDLGAKGYLVK-FDANRFIDEVSRVL-----
+-----TVLFVDDEQTVLEIGSEMLKELGFE-VATAADGGEALDIFKQDRFSFIILDLTMPRLDGEQTYRQLRQLKPEVKVIMSSGYNEQEINQRLGGTGLAGFIQKPYNLSMLRDVIRN-------
+-----TVLFVDDEQTVLDIGSEMLKELGFD-VVTAMDGSEALELFKQERYSFIILDLTMPRLDGEQTYRQMRELKPEVKVIMSSGYNEQEINQRLGGTELAGFVQKPYNLSTLRDVIKN-------
+-----TVLFVDDEKSYLAYTSELFVNRGLN-ILTAASALEALEIVEHQSVAVVVSDNEMPGMRGIELLSRIKDISPHTVKIMMTGSADLATTLAAINSGVFRFVLKPWKKAEMMRAVKDGIRRY--
+-----TVLFVDDEEMLLSNGSAMLHACGYE-VTTASSGKNAMELLRKDRYDIAVVDIIMPEFSGLECLKAIQKEVPSLPVILTSGNSGDEQISEGIEAGAAAFLPKPYSIETLSSLIADTLK----
+-----TVLFVDDEEELRIAVAQSLMLADLP-AEVYERAEDALAKISRSFQGVLVTDIRMPGNDGLWLMHQILEIDPEFPVILVTGHGDVDLAVRSMREGAYDFIEKPYPPARLVSTVQHALEKR--
+-----TVLFVDDEEELRHATRQTLMLADIP-ATILDKAELALAQISRGFPGVLVTDIRMPGNDGLWLMRKALEVDPEFPVILVTGHGDVNLAVSSMREGAYDFVEKPFAPSRLVSTIQRALDKR--
+-----TVLFIVDEPSVRMLIIDLLTEMGYA-AVQATDDVAGLKVLQFARIDMLVTDVGLPGMNGLQMADAARAHRPELKVLFITGYAECADIDDGRLGSGMQVLAKPFALDALGMRIKDLV-----
+-----TVLFIEDEPALGMIVKDSLTYRGFE-VLYAANGVEGLEQFRLHRPDIVVADIMMPDMDGFTMAEHIRRDDPHVPIMFLTARSQTADVVRGFELGGNDYLKKPFSLEELIVRINALLRA---
+-----TVLFAEDHADNRRFISRYLRSLGLD-VIAVENGEQAVERCLQDYPDLVLLDIQMPIMDGRAAFELLKKCGFQRPIFALTANAMSHEIDDYLTLGFDGYLAKPLDKDLFYKTLSENLDQ---
+-----TVLFADDDPHIRTLLSDTLTQAGFA-VLAAEDGLSLIRIAQEQLPDIILVDLMLPGVDGYEAIRQLRNRTAHLPIIIVTARANPSDVVIGFDTGADDYITKPFNEAELVARIRSLLRRIT-
+-----TVLCVDTPDRVSTVTDAVAAGDDLN-AVSATSVSDATEVLIDDPVVCVVTAYDLSDGTGLDIVGAIREHAPQTPCVLFTDASPGEIDTAAFEETIVEYLNRDLADERLSFVVDD-------
+-----TVLCVDTDARISTVSTAVETEDNLT-AIEARSVEDALDVIGSEPVVGVVTAYDLADGTGMDVIQAVREQTPQTPVVLFTDVSPAEIDTNSVEEVLVEYLNRDI------------------
+-----TVLCIDDEPAILRLLSVVLAADGHE-VMTATAGREALTIIGRGAVDAVLLDLGLADRDGLELIPAIRAI-TAVPILVISARGEVAEKVTALDLGAADYITKPFDGDEVRARLRVALRQ---
+-----TVLAVDDSPVMHGLVKQALGN-DYR-VLVTDNAVEALSLLYQEKVSILLLDVTMPEIDGLELCRTVRNQFQTLPIIMLTARDGAFEKVQGRLAGATEYLTKPFNPQTLSEVITQVLS----
+-----TVLAVDDSPSVRCMVAMTLREAGYR-VIEATDGREGLEKALSEPVDAIITDQNMPNLDGLGFIRAFREESKGKPIIFLSTDSADTLKQQAREAGAMGWMVKPFTQPQLLAVIKKVL-----
+-----TVLAVDDSPSIRQMVGLTLRGAGYN-VIEAVDGQDALEKATTLKIDAVLTDQNMPNLDGLGFIRAFRASSQGIPVIFLSTDSADALKQEARSVGALGWMVKPFSQAQLLSVIQKVL-----
+-----TVLAVDDSPSIRQMIKVVLGPAGHT-VIEAGDGAEGLAKARSESVNLVITDLNMPVMNGLEMIKQLRTSFTGVPILFLSTESDEGIKQQAKAAGATGWITKPFKPEQLLAVVGKLVR----
+-----TVLAVDDSKSILQMVSFTLKGAGYQ-VIEAGNGQEALAAAQKHKVDLVLTDLNMPVMDGLTLVQKLRATYKFTPILMLTTEAGADFKAKGKAAGLTGWLVKPFDPQKLLGVVKKVL-----
+-----TVLAVDDSASIRQMVSFTLKSAGYD-VVEAVDGMDGLEKAKTKSVNLILTDQNMPRMDGLTLIKNLRGQYASTPILMLTTESSDAMKSQGRAAGATGWLVKPFDPQKLIEVVRKVI-----
+-----TVLAVDDSAFIRKLIEKTLITAGYR-VISANDGAEAYDMLMGDHVSLIISDVEMPRMDGMHLVKRLRERYVKLPVIMFSSIMSEENRRKALLVGADDTVTKP-EIGTLVEMVDRY------
+-----TVLAVDDEPNILAALRRLFRATGWR-ILTAAHAEEALALLAAEPVDAVLSDMRMPGMDGVQFLERVSQGWPRTARLLLTGQADLGSTIAAINRGLHRYITKPWNDEELVLTLRQVAQNQ--
+-----TVLAVDDDIDILRMLNRYFAARTFN-LITAESGAGVVQRLT-NNPDLILLDVNLPDTDGFSLAERIRAI-TSVPIIFLTARVTDEDKVRGLGAGGDDYVTKPFSLAELGARIKAHFRRE--
+-----TVLAVDDDIDILRMLNRYFAARTFN-LITAESGAGAVQRLT-NNPDLILLDVNLPDTDGFSLAERIRAI-TSVPIIFLTARVTDEDKVRGLGAGGDDYVTKPFSLAELGARIKAHFRRE--
+-----TVLAVDDDIDILRMLNRYFAARTFN-LITAESGAGALQRLT-NNPDLILLDVNLPDTDGFSLAERIRAI-TLVPIIFLTARVTDEDKVRGLGAGGDDYVTKPFSLAELGARIKAHFRRE--
+-----TVLAVDDDARNLFALSGILELHGLR-VLHAENGRKGIDILTAHPIRLVLMDVMMPEMDGYAATAEIRKEYHDLPIVAVTAKAMPGDREKSLASGASDYVTKPVDAGDLIACVRRWLS----
+-----TVLAIDDSLTTRQTLSTTLQKAGYR-VIQAQDGADGLNQLELHPVVGIICDVEMPNMNGFEFLGRCRKKKAELPVLMLTSRGSKRYRQLAQQLGANGYLTKPYLDQELIETLQGAIAET--
+-------------------------------TVLAADGVDALELLGGFTPDLMICDIAMPRMNGLKLLEHIRNRGDQTPVLVISATENMADIAKALRLGVEDVLLKPVKLNRLREMVFA-------
+---TVKVVLLDDEELVRKGIRMVLHEPDIEVVAEGDDGSVAVDLVAEHRPDVVLTDIQMPRVGGLEVARRLAALPDPPAVAALTTFDVDEYVYAALQHGAAGFLLKDTSPRELADAVRVLAR----
+---TVKVLVVDDSSFFRRRVSEIINDPRLEVIGNAVNGKEAVELVQKLQPDVITMDIEMPVMDGITAVREIMKV-LPTPILMFSSLTQEKATLDALDAGALDFLPKKFE-----------------
+---TVKVLVVDDSSFFRRRVSEIINDPRLEVIGNAVNGKEAVELVKKLQPDVITMDIEMPVMDGITAVREIMKV-LPTPILMFSSLTQEKATLDALDAGALDFLPKKFE-----------------
+---TVKVLVVDDSAFFRRRVTEILENTNIKVIGSANNGEEAVEQSRTLKPDVITMDIEMPVMNGIDAVKAIMSS-NPCPILMFSSLTHETATLNALEAGAADFLPKKFE-----------------
+---TVKVLMVDDHPLFRQGVRWALSERDIKIIGEGSSAEEGLVLISEHEPDVVLTDLNLPNMDGLEFTRTIRRQYPNIGVVMLSVYESDEHAFNALRAGAAAYYSKEISPKTLATVLRRVAR----
+---TVKVLIVDDSPTMRAILSMMISDPEIEVVGKADCPSTARQMIKELNPDVMTLDIEMPGMDGLDFLEKVMRL-RPMPVIMVSALTAAEATLKAMELGAFDCFAKPA------------------
+---TVKVLIVDDSAVVRQVLTEQLAIAGITVMGAARDPLFARKLLETQWPDVIVLDIEMPRMDGLTFLRQLMAE-RPTPVIICSTLTEQEITMQAMSAGAVDIIAKPIGLRQFLEE----------
+---TVKVLIVDDSALMRKLFTQLFEKEGFI-VQVARNGEEALTKAVEFEPDCITLDINMPVMDGMTCLAMLKKL-YPCPIIMVSSLTQKSITLEALALGASDFVLK--------------------
+---TVKVLIVDARPERSRALEQALHEAGFDVVTRVDEHDDLYAIMTREVPDAVIIDAALPSRDTLEHMGQLGRRFPK-PMIMLAEEETPELTREATSVGVSAYVVEDVQPALVRSMVNVAIA----
+---TVKLLVVDDERPVLDAIKRAFKPYTAQELQSTSSGVEALLLVSEQKPHGMLIDLNMPDIDGLEVCRRIRAQMESVRLITMTSNHSPEVVEQSKQAGAIACLAKPLDVQQVLELF---------
+---TVKLLIVDDHPLFRQGVRWALSEPGIQIVGEAANGEEALRWLAQSEPNVMLVDLNLPGMSGLELTRQIRRQYTSIAVVMLSMHENDEAAFNALRAGAAAYRSKDIKPAALADILRRVAH----
+---TVKIVVVDDQAMVRSGFVALLSQPDIEVVGTAADGSEALQVVRRTHPDVVLMDVRMPVMDGIEALRQLSEATAQTKVVMLTTFDADEYVHESLRLGASGFLLKDASPDELASAIRVV------
+---TVKILLAEDDNDMRRFLVKALEKAGYK-VLSYDNGASAYDRLREEPFSLLLTDIVMPEMDGIELARRATELDPDLKVMFITGFAAVALNPDSKAPKDAKVLSKPFHLRDLVNEVNKMLA----
+---TVKILIADDQVLLSRALATILGQPDLEVVATVHDGQAAVDTVAHTPVDLVLMDVRMPKLDGVAALKKIRAKPNPPKIVMLTTFNVPDTVKAALTAGANGFLLKDADPETLIESVRTVAA----
+---TVKILIADDQVLLSRALATILGQPDLEVVATVHDGQAAVDTVAHTPVDLILMDVRMPKLDGVAALKKIRAKPNPPKIVMLTTFNVPDTVKAALTAGANGFLLKDADPETLIESVRTVAA----
+---TVKIAIIDDHQLFREGVKRILEEKTFEVVAEGEDGEEALDIIEKYHPDVVLMDINMPHQNGVEATRKLIEAYPETKIIILSIHDDESYVTHALKSGATGYLLKEMDSDALIEAVKVVA-----
+-----TVIVVEDDPTLQALLVEILIELGAT-CDAFDNSEDALIHLMGSDCSLIVVDHGVPSIKGMEFISMAHERWPGLPAILTSGYQLD----ASQVTPPVTYLFKPWSIDELTQAIGQALH----
+-----TVIVVDDSLFMRTVLKDILLDLGHAVIAEAENGYDAVLKYAHFRPDLITMDINMPKMDGLEAVKKIVELDPQANILMCSALGQQEAIIKAFKAGAKDFIVKPFEMERVVNAVTKLLD----
+-----TVIVVDDQHSHREMISNLLKGSGIN-VIEASDGVEAIEKIEVNCPDLIILDIVMPGMNGFEVCRRLKNLTQNIPIVFCSVKGEEFDRYWGIKQGADAYIAKPFGPRELVGTVKQFLR----
+-----TVIVVDDQALIRTAVRDLLDAEGISVVGEAADGEAGVDLARRLRPDVVVSDIRMPRRDGIELTALVCDALTETRVLILTTFEEDDYVVAALRAGASGFIGKGAEPEDIVRAVLSV------
+-----TVIVIEDDPTLRTLLVEILSELGAA-CAAFDNAEDALISMMSDECSLIVVDHGVPSIQGMEFISMAHERWPGLPAILTSGYQLDA----SQVTPPVIYLFKPWSIDQLADAICKALSAA--
+-----TVIVIDDDEMMRDSIDGLLRSVGIA-TRVFPSAVAALAEVWPTGPSCMVVDIRMPHLGGLELQERLNETGKTVPVIFITGHGDIPMTVKAMKAGAVDFLTKPFREQDLLEAVHIALDRA--
+-----TVILVEDDSAIAEPLARALSREGYD-VRSHDTGAAALTEVEA--ADLFILDLGLPDMDGLDVARHVRKLGKTTPILILTARADEIDMVVGLDAGADDYVTKPFRLAELLARVRALLRRIG-
+-----TVILVDDSRTILASAELALEDIQIH-FLTYSNPQQFLDEVFAGSYDLLISDINMPQVSGLEVSARLKQRFKSKPILILTTESSAEMKEKGKAIGVTGWMVKPFSDEKLVKSIKLV------
+----TVILTVDDDPGVSRVIARDLRRRGYR-IVRAESGESALEALRELKVAVILADYRMPRMNGIEFLEQALNVYPGARRVLLTAYADTGAAIDAINVDLDHYLLKPWDPPE--------------
+----TVILTVDDDPGVSRAVARDLRRRGYR-IVRAESGESALEALRELKVAVILADYRMPQMNGIEFLEQALTVYPGARRVLLTAYADTNAAIDAINVDLDHYLLKPWDPPE--------------
+----TVILLVEDNVINLKVLVHSMKKLKEE-YDTASNGLQAFEKYKKAPFKIIIMDISMPIMDGLTSTRHIREGLSRVRIVALTCFGTEEHRRDAAMSGVDLFLTKPIHLKSLKPVV---------
+-----TVILIDDDSDVLHSCAQSLELAGLR-VETSERADAVVKWLGPDTNGIVVTDIRMPGLDGIALLRAVQTADRDLPVILMTGHGDVPLAVEAMRAGAYDFLEKPFDPAQLVLTVTHALEKR--
+-----TVIIVEDEVEVAHLVAQYLFTSRYKVIGMASDINTARSLLGAITPDLLLLDVYLPDGNGLNLLAELRSQGICSEVVLLTAAKEVQILEKAMQLGVFDFLVKPVLLSRLDQALSRFE-----
+-----TVIIVEDEVEVAHLVAQYLFTNRYKVIGMASDISTARSLLGAIVPDLLLLDVYLPDGNGLNLLAELRSQGSRSEVVLLTAAKEVQILEKAMQLGVFDFLVKPVLLSRLDQALSRFE-----
+-----TVIIVEDEVEVAHLVAQYLFTNRYKVIGMASDISTARSLLGAITPDLLLLDVYLPDGNGLNLLAELRSQGIRSEVVLLTAAKEVQILEKAMQLGVFDFLVKPVLLSRLDQALSRFE-----
+-----TVIIVEDEVEVAHLVAQYLFTNRYKVIGMASDICTARSLLGAITPDLLLLDVYLPDGNGLNLLAELRSQGIRSEVVLLTAAKEVQILEKAMQLGVFDFLVKPVLLSRLDQALSRFE-----
+------TVIINDNANYFKEITSLISNKELNLIANYENPIRCLTELKKRELKVVIMTTNIMGYSGLEVAKQIHHLDKKIKIIFIADNH--DYAVEAFDVGAFDYLLWPVEEKRFRETINRL------
+-----TVIICDDERIIREGLKSSIQDYNFNEVLLAKDGEEALELIHLNHPLLVIIDIRMPKMNGIQLLENIKDI--SCEKIILSSYDDYEYMKAGIQHKVTDYLLKPINQQELKQILNKIYEKY--
+-----TVIIASADSNFRQMVKSAVKNLDYIVVGECADGPTALKMARNFQPDMFIIDDHLIGVPGREIAKILSF-DRQCAVVLAMEFEIDKLDEFLGEMGVVGVVIKPLEEEQLIMTVQ--------
+-----TVHVIDDDMAVRQSLAFLLQTVGIP-VRVYDSAVAFLNALPAVQRGCVVTDIRMPEIHGLELQRRLKPLDLSLPIIVITGHGDVPLAVEAMKAGAVDFIEKPFDDEVVLSAVRSALD----
+-----TVHVIDDDLAMRESIEFLLSSAGYE-VKLYESAQTFLDLPD-VEFGCILSDVRMPGIDGLDLLKRQKAAGSKLPVLIMTGHGDVPLAVEAMKLGASDFIEKPFDDDRLIGLIELALKQA--
+-----TVHVIDDDLAMRESIEFLLGSAGYE-VRLYESAQAFLDEPE-VEFGCILSDVRMPGIDGLDLLKRQKAAGSKLPVLIMTGHGDVPLAVEAMKLGASDFIEKPFDDDRLIGLIELALKQA--
+-----TVHIVDDDKSFRAAVGRMLAASGFQ-IESYSSGEELLARLPR-GSGCILLDLQMPGLSGLELQARLADLAPLLPVVFLTGRGDIGITVRAMKAGAHDFLEKPASSAAVLEAVERALQ----
+-----TVHIVDDDADFRDGLAWLLDSRGLP-TRSWSGGDMFLQSLRPGNCCVVLLDIRMEPLSGLATFEQLKAMGWPWPVLFLTGHGEMSMAVAAVKNGAWDFLEKPFQNNLLVDKVEAA------
+-----TVHIVDDDAALREALDSLFRSVGLE-TRLFANAQAFLESGAAQEAGCLVLDVRLPGLSGLDFQEKLAAADVRMPIVLMTGHGDIPMSVRGMKAGAVDFLTKPFRDQDMLDAVASALQRD--
+---TVHILVIDDDSSLCTSLSYYLERHGYT-VHSASDALQALDVLERHPVGFVITDYLMPHLDGIHFTEIVKARFRSIPVLLITAVVDGSVTDKSLRKGVALTLQKPVDMGQLLNLVR--------
+---TVHIGLVEDDTNIQNIVSAYLKKEGYQ-TTILDNAEDGWKLWENNPPDMWILDIMLPGMDGYEFCKKIRNE-SDVPIIIISAKDEEIDKILGLELGGDDYLTKPFSPRELIARVKRLFKRS--
+------------------------------TVHEAATVAEARARAQAGPCDLAILDLGLPDGSGIELVTELRSH-GWPRVVVLASSDDPYAVRSAFQAGAQAYLLKSASPVVVTDGVRRVLE----
+-----TVGVLDDDPAVLQSLRFLLETHGFK-VRTFSSALTLLTSIDPDNVDCLVIDYKLPDIDGLNVAERLRERNVAVPIVLVTGHPHQHMAKKAAAAGIDHILLKPHLGDNLVTHVQEAISRK--
+-----TVGLADDQQLVRAGFSMVLGQDDIEVVWEANNGREAVMLAQRQPVDVILMDIQMPVVNGIDATKEIVAQGELTRIVVLTTFDTDNYVVQSIEAGASGFLLKDTSPEELISAVQSVGE----
+-----TVFVVEDDADIARLVRYHLEGAGFA-VRTFLTGNGVIPESEKTPPNLFLLDIMVPGADGLEICRQIRHSIAMTPVIFLTAKTSEADKIAGLDLGADDYIAKPFSPRELIARIKAVLRRF--
+-----TVFVVDDSRTAREVVRLHLTRLGCE-AVALEGGEACMAELARRTPALILLDLRMERMQGDEVCRLVKAAGRNVPVIMFTSGGEPHEVMHCWRAGADDFLPKPVALGALEAKLAAVRQ----
+-----TVFVVDDEESVRHSLNWLLSSIALD-VKMYDSAQAFLDADISCSYGCLILDVRMQALSGLQLQEALCARGFSLPIIFLSAYGDAQIGAQAIKKGAIDFLQKPYRNQDLLDAVNAALT----
+-----TVFVVDDEASVRDSLTWLLNSISLD-VRTFESAKDFLDADISCTHGCVVLDVRMQNVSGLQLQQALSERGFKLPIIFLSAYGDAQMGAQAVKKGAFDFLQKPYRNQDLLDAVNAALA----
+-----TVFVVDDDNMVRTALLRLLASAGYA-AHGFASADEFLQARLPAVPCCLLLDMKMPGSDGFEVVRRLERRGDAIPVIFISGYGTIPTTVQAMKAGAHEFLTKPIQDERLLGAVEEALQ----
+-----TVFVVDDDISVRESLELLIGSAGWR-PILFDSAQAFLSATPNAGPSCLVLDVNMPGLNGLDLQSLITKSGNRTPIIFVSGFGDVPMTVKALKGGALDFLTKPIDAEALLAAIQSALSQS--
+-----TVFVVDDDEDLRDSVVTLLRASGYV-VRSFVSGDDFASKYQQTQPGCLLLDIRMPGIGGLELYQQLLLQGRRLPVIFMTAHASVEIAVTAMKSGAIEFLEKPFESQRLLKLVAQALE----
+-----TVFVVDDDEAVRDSLRWLLEANGYR-VQCFSSAEQFLEAYQAGQIACLILDVRMSGMSGLELQERLIAENAALPIIFVTGHGDVPMAVSTMKKGAMDFIEKPFDEAELRKLVERMLDKA--
+-----TVFVVDDDEAVRDSLRWLLEANGYR-VQCFSSAEQFLDAYQAGQIACLILDVRMSGMSGLELQERLIAENAALPIIFVTGHGDVPMAVSTMKKGAMDFIEKPFDEAELRKLVERMLEKA--
+-----TVFVVDDDEAVRDSLRWLLEANGYR-VQCFSSAEQFLDAYQAGQIACLILDVRMSGMSGLELQERLIAENAALPIIFVTGHGDVPMAVSTMKKGAMDFIEKPFDEAELRKLVERMLDKA--
+-----TVFVVDDDEAVRDSLRWLLEANGYR-VQCFSSAEQFLDAYQAGQIACLILDVRMSGMSGLELQERLIADNAALPIIFVTGHGDVPMAVSTMKKGAMDFIEKTFDEAELRKLVERMLDKA--
+-----TVFVVDDDEAVRDSLRWLLEANGYR-VQCFSSAEQFLDAYQAGQIACLILDVRMSGMSGLELQERLIADNAALPIIFVTGHGDVPMAVSTMKKGAMDFIEKPFDEAELRSLVERMLNKA--
+-----TVFVVDDDEAVRDSLRWLLEANGYR-VQCFSSAEQFLDAYQAGQIACLILDVRMSGMSGLELQERLIADNAALPIIFVTGHGDVPMAVSTMKKGAMDFIEKPFDEAELRKLVERMLDKA--
+-----TVFVVDDDEAVRDSLRWLLEANGYR-VQCFSSAEQFLDALQAGQIACLILDVRMSGMSGLELQERLIADNAALPIIFVTGHGDVPMAVSTMKKGAMDFIEKPFDEAELRKLVERMLDKA--
+-----TVFVVDDDEAVRDSLRWLLEANGYR-VQCFSSAEQFIDAWQPHQIACLILDVRMSGMSGLELQERLIADNTLLPIIFVTGHGDVPMAVSTMKKGAMDFIEKPFDEAELRKLVERMLDKA--
+-----TVFVVDDDEAVRDSLRWLLEANGYR-VQCFSSAEQFIDAWQPHQIACLILDVRMSGMSGLELQERLIADNASLPIIFVTGHGDVPMAVSTMKKGAMDFIEKPFDEAELRKLVERMLDKA--
+-----TVFVVDDDEAVRDSLRWLLEANGYR-VQCFLSAEQFLDAWQPHQIACLILDVRMSGMSGLELQERLIADNASLPIIFVTGHGDVPMAVSTMKKGAMDFIEKPFDEAELRKLVERMLDKA--
+-----TVFVVDDDEAMRDSLTWLLEGNGYT-VRTYRSAEEFLVDDKREGVGCLILDVRMQGMSGPELQDRLLAENSRMPIVFVTGHGDVPMAVSTMKKGAVDFIEKPFDESELRELVERMLSKA--
+-----TVFVVDDDEAMRDSLTWLLEGNGYT-VRTYRSAEEFLVDDKREGVGCLILDVRMQGMSGPELQDRLLAENNRMPIVFVTGHGDVPLAVSTMKKGAVDFIEKPFDESELRELVERMLSKA--
+-----TVFVVDDDEAMRDSLTWLLEGNGYN-VRTYRSAEEFLVDDKREGVGCLILDVRMQGMSGPELQDRLLAENNRMPIVFVTGHGDVPMAVSTMKKGAVDFIEKPFDESELRELVERMLSKA--
+-----TVFVVDDDEAMRDSLTWLLEGNGYN-VRTYRSAEEFLDDKRSEGVGCLILDVRMQGMSGPELQDRLLAENNRMPIVFVTGHGDVPMAVSTMKKGAVDFIEKPFDESELRELVERMLSKA--
+-----TVFVVDDDEAMRDSLTWLLEGNGYN-VRTYRSAEEFLDDKRNEGVGCLILDVRMQGMSGPELQDRLLAENNRMPIVFVTGHGDVPMAVSTMKKGAVDFIEKPFDESELRELVERMLSKA--
+-----TVFVVDDDAAVRDSVSALLESASFR-VENFDSAASFLASRATERPGCLVVDIRMPDMDGLELQEEMVRRQIALPVIVMTGHADVPLAVRAMKAGAVDFIEKPFNDELLLDSVARALE----
+-----TVFVLEDDLDISRLVQHHLEGAGFQ-VRSYLTFGSIVEDAEKSRPALFLLDVMVPGGDGMELCRRLQRLLSGVPIIFLTARATESDRVLGLDLGADDYITKPFGTRELVARVKAVLRRF--
+-----TVFVLEDDADISRLVQYQLERAGFI-AKPYAAIGSIVQDAERSRPALFLLDIMVPGGDGMDLCRRLRQHLSGVPVIFLTARASENDRVHGLELGADDYITKPFGTRELVARVRAVLRRF--
+-----TVFVIDDDELDILMYERVFQRSAVERAVNFSFAQSALEVLDSERPELIFLDINMPGMSGFDFLRAIEDDLEMFPTVIMSTSDLAEDREQARSFNVIAYFTKPVSMIRLLTCCTRASR----
+---------------------TVFSLDGHQ-PLCAADGQHALELFKQQAPDIVLMDIRMPKVSGLEALQVMRQIRQETPVILMTAYAAVETAVEALRLGAFDYVIKPFDLDELKIIISRAMQ----
+-----TVFLVEDEAMIRMMVVDMLEELGFSVAAETGEINEAVKLAGTTDFDVAILDVNVNGKVISPVADVLKAR--NRPFIFATGYGTQGVPEDYRDRPA---LQKPFQIESLKQALDTTLR----
+-----TVFLVEDEAMIRMMVADMLEELGYHVAAEAGEINEAIRLAGTTDFDIAILDVNVNGKVISPVADLIKAR--NRPFIFATGYGTQGVPEDYRDRPA---LQKPFQIETLAEVIASTLK----
+-----TVFLVDDHEVVRRGLVELLEDPDLSVIGEAGNCSHALARVPALRPDVAVIDVRLPDGSGIDLCRELLAKVPGLRCLILTSFTEDQAMLDAIMAGASGFVIKDITGMELAKAVREVG-----
+-----TVFLVDDHEIVRRGLADLLTSDGHRVVGEAATVREALARIPAVAPQVAVVDVRLPDGSGIDLIRTLRDQHPRLPCLVLTSYSDDEALLDAITAGAQGYVLKQIRGTELVSAIATVA-----
+-----TVFLVDDDQGMRDSLTLILELAGYP-VRSFPTPAAFLAAFSPDERGCLVLDQRMPDMTGLDLQSELLERGALLPIIFLSAFGDVPTTVRAIQGGAIDFLEKPASTEQLLQRIEDAFAE---
+-----TVFIVEDDPSVRDALGLLLGLHGLT-VALFADAESFLAARRPDWYGCLLIDIRMPGMNGLALQKHLLESGCWLPVIVMTGHGDVDSARQAFRAQAVDFVEKPIDHDRLMRAIEEAFARQ--
+-----TVFIVDDHPLLLRGLADLIADSGYRVIGTALDGRSALTMIRQDLPDVAVIDLNMPGFSGLDLAFELGKETPTTRCVMLTAGASQSQLYEVIKAGVAGIVLKEAAIGTLLRCIHRVA-----
+-----TVFIVDDDEAVRDSLRWLLEANGYR-VRAYASGESFLEDYDASQIGVLIADVRMPGMSGLELQEQLLARNAPLPIVFITGHGDVPMAVSTMKKGAVDFLEKPFNESDLREIVARMLEQA--
+-----TVFIVDDDEAVRDSLRWLLEANGYR-VRAYASGESFLEDYDASQIGVLIADVRMPGMSGLELQEQLIARNAPLPIVFITGHGDVPMAVSTMKKGAVDFLEKPFNESDLREIVARMLEQA--
+-----TVFIVDDDEAVRDSLRWLLEANGYR-VRAYASGENFLDEYDASQIGVLIADVRMPGMSGLELQEQLIARNAPLPIVFITGHGDVPMAVSTMKKGAVDFLEKPFNESDLREIVARMLEQA--
+-----TVFIVDDDEAVRDSLQWLIETEGYQ-VKTYEDPELFLEQLVWPQPCVLLLDIRMPKLSGLEVQKTLNERGIPIPIVFITGHGDVTLAVETMKNGAVDFLEKPFDEGKIKDLIHQHMRHA--
+-----TVFIVDDDEAMRDSLTWLLEGNGYQ-VRSFTSAEQFLAAYDASQVSCLILDVRMPGMSGPELQERMLAEQIDIPIVFITGHGDVPMAVSTMKRGAIDFIEKPFDESELRALVERMLTKA--
+-----TVFIVDDDEAMRDSLTWLLEGNGYQ-VRSFTSAEQFLAAYDASQVSCLILDVRMPGMSGPELQERMLAEQIDIPIVFITGHGDVPMAVSTMKRGAIDFIEKPFDESELRALVERMLQKA--
+-----TVFIVDDDEAMRDSLTWLLEGNGYQ-VRSFNSAEQFLSAYDASQVSCLILDVRMPGMSGPELQERMIAENIDIPIVFITGHGDVPMAVSTMKRGAIDFIEKPFDESELRSLVERMLQKA--
+-----TVFIVDDDEAMRDSLTWLLEGNGYQ-VRAFSSAEQFLAAYDAGQVSCVILDVRMPGMSGPELQERMIAENIDIPIVFITGHGDVPMAVSTMKRGAIDFIEKPFDESELRSLVERMLQKA--
+-----TVFIVDDDASIRRSLERLIKSVGFQ-VESFASAQEFLRREPTIRPAGLVLDVRMPGPSGFDLQDKLAFLHCNLPIIFITGHGTIPLSVRAMKGGAIEFLTKPLDEQYLLDAIHKAVE----
+-----TVFIVDDDASIRDSLSLLLSLRGYA-TALFANAEDFLAALQPDWRGCVVVDIRMPGMSGLELQRCLRERGPSLPVIVITAHGDVAAARQAFLADAVDFIEKPFDGKQLLGAIENALS----
+-----TVFIVDDDASIRDSLSLLLSLRGFA-TALFANAEDFLAALQPDWRGCVVVDIRMPGMSGLELQRCLRERGPSLPVIVITAHGDVAAARQAFLADAVDFIEKPFDGKQLLGAIENALS----
+-----TVFIVDDDAGMRESIHDLVESVSLH-AESFSTAQGFLSGERRDGPSCLVLDVRLPDTSGLDLQQELSRAGIKIPIIFITGYADIPMTVKAMKLGAVEFLTKPFREQDLLDVIHRALRRD--
+-----TVFIIDDHPVIRLAIRMLLEHEGYKVVGETDNGCDAIQMVRESLPDLIILDISIPKLDGLEVLCRFNAMNTTMKTLVLTAQSPTLFATRCMRSGADGYVCKEGDLSELLSAIRAVLS----
+-----TVFIADSHPVVQVGITQMLSETGFKVIGTARTSSELFEKLENETPDILMLEMDFPEINGIACLRKMKKNHPDVKVLMYSGQSEDVYAISSIRAGAQGYLSKNADLDYIVAALEKIS-----
+-----TVFIADDDEIFLAGTIDLFQRMGYA-IDSARSVNEALAKLDTHQWSLAVVDLLMPMANGLKVIQQIKQKMPWLGIIVVTSYR---------------------------------------
+-----TVFAIDDSPLNLKILQRFLEKQGWK-VFIAEDGLTAITEINQVQPDIIVLDIMMPGIDGFEVCRRLKAATAEIPIIFLSALTDQKSIVKGLELGAVDYIHKPFQQEEIITRLQL-------
+---------------------------TVE-IVTAMNAQEAASALAAGPCHCVVLSLDLPDGEGPRLLEAVDGALATVPLLVHNNHRPSAAQEAALQARAENSLEVLSSLDELKERI---------
+--------TVDDQPEVRSALRLMLGEPDIAVVGEPVDGDHARDVIEACRPDVVLMDLRMPRCDGLVATARETALRPETAIIVLTTFDTDHHVVRALRAGACGFLLKDAPPDELAHAVRAAAQ----
+-----TVCVVDDDKIYVYGLKKLMSLKQLSNLIEFPNGKEAIDFLINPDPDVIFLDINMPVMDGWDFMENYARLGKKITVYMVSSSINQEDINRAKNSHITDYVVKPVTYDKLLELFKEA------
+-----TVCIIDDDPIFVYGTKVILNSNGCSNIMVFEDGEEALDDLNQTLPEVIFLDLNMPIMDGWDFLDEFCKIENKTRIYILSSSIFSVDIEKSKEYKVKDFISKPLTDSKFEILLKD-------
+-----TVAVVDDDAAARISLVRLLQLEGYH-VHEYDSASSFLEGAENRAYSCIVTDLRMPGVTGLDLQKSLEGRGVFVPLVFVTAFGTVPASVQAMRSGAVDFLEKPADPSALLDAVKRAVARC--
+-----TVAVIDDNPDHRALVRDILDPLGFV-VLEAASANQCVEVVLPLKPDLYLVDILMPGTNGWELIKDLRMKGEMAPIIMLSANIGDQALKPEGPANHTASLAKPFDIHQLLDLIQQH------
+-----TVALVDDHDVIALGVTTMLATASLHFRGGYPSVAQLLEETAATKPDVVLLDLRLPNSDPSHNARTLRTR--GAAVIAYTSGDDPYLIRRACEGGVLGVVRKSETPDVLISTIWAALR----
+-----TVALVDDDRNILASVSIALEAEGFD-VRTYTDGAEALRGLSQRPPDLAVLDIKMPRMDGMELLQRLRQT-SQMPVIFLTSKDDELDELMGLRMGADDYIKKPFSQRLLIERIRALLRREA-
+-----TVALVDDDALVRAGLSLILGDPELRIVGEAADGVAAIELVRRERPDVVLMDIRMPRLDGLAATQRLVAAGTRSRIIVLTTFDADAMVLEALQAGAAGFLLKDTPPERLVAAVHAAA-----
+-----TVALIEDDADFRQALVERLTLEGLE-VRAFTAAEPALKALDADFPGVVVTDLRMPGMDGRQLLTRLQALDTSLPVIMITGHGDIADAVAAMHDGAYDFVAKPFPFERLQDSLNRALEKRS-
+-----TVALIDDHDVIALGVTTMLASLHFR--GGYPSVAQLLEETAATKPDVVLLDLRLPNSDPSHNARTLRTR--GAAVIAYTSGDDPYLIRRACEGGVLGVVRKSETPDVLISTIWAALR----
+-----TVAIVEDNRDFRATLARYVDEAGHRCICECGTSEEALQKLPRLMPDVVLMDIHLPQMSGLDCTRRLKEICPSIQILILTVYEDNERIFGALKAGAGGYLLKRADPADILSAIQDV------
+-----TVAIVDSDREFATNLATQMGYFDLQ-AHTYTSTTAFLADLNETLPGILVISAQLSKGNGIAVASEAASRLAERPRILISSDDDMKLRLACVRAGGEAFLVKPFEATQVIALINK-------
+-----TVAIVDDDGGVRTSLTSLVRSLGYQ-VRAYTSAREFLDDKQSPEPDCMIADIQMPHMTGDRLQAVLSSSGRSFPIIFMTAFPSEAVRDRVMAAGARDYLEKPPDSDVIARRLADLL-----
+-----TVAILDDDPLSCEALSSLLRADGYC-ALTFGSVNDLLRSGP-ERFGCIFSDIWMEGQTGIDLLEILAGQGNMPVVILMTARFDRDQAAHAMEIGARAVLEKPLSAERVSELV---------
+-----TVAIIEDQTAIREMMSQILDRDEFEVVLECGDGQIGLERTLELKPDFVILDVMLPNLNGTEILRRLAKELPDARVLIFSGYQTPGLVRELLQAGAHGFVEKAAPLTELRKGIE--------
+-----TVAIADDQAMQRFGFRMLLESQDMALVGEAETGSAAVRLCAELQPDVVLMDIRMPGLDGIEATRRIVASGGRTRVLILTTFDLDEYAHAGLRAGASGFLVKDARPEELLAGIRAVA-----
+---TTYVLLVDDNPNNLKVLSEAIQRCGWK-ALMATDGESAIRQTEYAHPDLILLDVMMPGLDGFETCRRLKALTYNTPVIFMTALCDPTDKVKGLEIGAVDYITKPFQHEEVIARLKLHL-----
+--TTYTVLFVDDEPNILRAIKRALFTMDIT-LLLADSGAKALELMSANEVHVVISDMKMPQMSGAELLEQVAINYPETFRVVLTGYADIESTIKAVNQGIHRYLQKPWDNQELISVVEEGLERV--
+--TTYTVLFVDDEPNILRAIKRALFTMDIT-LLLADSGAKALDLMSKHDVHVVISDMKMPQMSGAELLEQVAINYPETFRVVLTGYADIESTIKAVNQGIHRYLQKPWDNQELIAVVEEGLERV--
+--TTYTVLAVDDEPSIGKLLEKELSTPTRT-VHVATSARQARERLRRATYEVVVLDIRLPDADGIEFMVELRQRYPDTEVILITGHGNIDNAVEAMKLGAYDYITKPFNLTELEVVVERAYQRA--
+--TTYTVACIDDSPTVLNAIQKFLEDQSLS-VVAINDPVKALMQIVRSKPDLVLLDITMPNLDGYDLCALLRRRYKHTPIVMVTGNTGLIDRARAKLVRASGYLTKPFTQDDLLKMVFKH------
+--TTYTIACIDDSTTVLNAINSFLDDKSFS-VVMINDPVRALMQVVRIKPDLILLDVEMPNLDGYELCSLLRKHFKTTPIIMVTGHTGFLDRAKAKLVRASGYLTKPFNQSELLKMVFKH------
+--TTYRVLVAEDDPINGKIVQKRLGKIGHA-VRLTVNGEECAAAYRADPYDVVLMDIQMPLVDGMSSTRMIRELNGRVPIFAVSASLLEKDASLYMDTGFDGWIMKPINFSRLNTVLDGL------
+----TTVVLVDDHQMFRSGVKAELGD-GVEVVGEAGDVDEAIAVITATEPDVVLLDVHLPGGGGIEVLRRLHGK-VRSRFLALSVSDAAEDVIGVVRGGARGYVTKTISGPELTDAIGRVAE----
+----TTVVLIEDEKQIRRFVRAALEGEGMV-VHDAETGKQGLVEAATRKPDLVIVDLGLPDTDGLDVIRELRG-WSELPVIVLSARTQESEKVAALDAGADDYLTKPFGVSELLARIRAHLRRR--
+----TTVVIADDHSIIRDAIYDLLSVANFEIVGTAENGLEAIAAIKAKRPGLLFLDVSMPLAGGAEIIHDVRRWSPDTRIVIFTGVTSPSVLAGILEAGADAIFSKLSPARDML------------
+----TTVVFVDDNDNYLDALRRFFPDVSTN--LFFSRPQTALAFIRE--FAAVVVDYDMPGVSGVEFLSSISNL--HCAKILLTGVADETVAVKAFNAGIVDLYLRKTDADS--------------
+----TTVVFVDDNDNYLDALRRFFPDVSTN--LFFSRPQTALAFIRA--PAAVVVDYDMPGVSGVEFLSSISNL--HCAKILLTGVADETVAVKAFNAGIVDLYLRKTDADS--------------
+----TTVVFVDDNDNYLDALRRFFPDVSTN--LFFSRPQTALAFIRA--PAAVVVDYDMPGISGVEFLSSISNL--HCAKILLTGVADETVAVKAFNAGIVDLYLRKTDADS--------------
+--TTVRVVLVDDETLVRVGLRLILGDPAIEVVGEAADGVEALDVIAATSPDVVLMDIRMPRLDGLGATERLLAAQPDARVVILTTFDTDEMVLGALRLGAAGFLLKDTPPAEIVRHV---------
+--TTVRVLLADDEHLIRGALAALLSEDDLVVVAEAATGPEALAMARAHAPDVAVLDLQMPGADGVKVATSLRAELPACKVLIVTSHGRPGHLKRALAAGVRGFVPKTVSAQRLAELIRTVH-----
+--TTVRIFLVDDHEVVRRGVADLLEEPGLEVVGEAGTCAEALTRVPALRPDVVVLDVRLPDGDGVSVCRELRSR-LDVACLMLTSFDDDEALFDAILAGAAGYVLKQVRGTDLVAAIRTVA-----
+----TTVMVVDDSVTVRKVTSRLLERNGME-VITAKDGVDAIALLQDHKPDVMLLDIEMPRMDGFEVASLVRHRLKDVPIIMITSRTGQKHRERALSIGVNEYLGKPFQEKILLETIERLV-----
+----TTVMIVDDSLFMRKMLRDILTEEGYEITAEASDGNEAIEKYQECRPDLVTLDIVMPNKTGIEALQIIMVLDPQARVVMCSAIGQESMTEAAAKAGAKAFILKPFNPELVARTLREVAE----
+----TTVMIVDDSLFMRKMLRDILTEEGYEIIAEASDGDEAVAKYRECRPDLVTLDIVMPNKTGIEALQIIMALNPQARVVMCSAIGQESMTEAAAKAGAKAFILKPFNPELVARTLREAA-----
+----TTVLVVEPDLDTQRVYRQRLHDPDIKLIGICSSIASATALLAQTNCDILFTELNLPDGDGLDFIRRASEDLAVQSIVAVTSKNSAADIATAIENGAVGYITKQ-------------------
+----TTVLVVEDTLSEQELISLYLRKAGYT-VITANDGKEAIEKTLAQKPDVIVTDVVMPNMNGFELCRSIKKQTQKLPVIACTSKTQDLDRLWGMKQGIDVYVTKPFTPEELIRAVKSV------
+----TTVLVVEDEPAIAQAVAHRFSAEGWR-VEVAADGPSGVSAATRVQPDLVVLDVMLPGIDGLEVCRQIQAE-RPVPVLMLTARDDETDMLVGLGVGADDYMTKPFSMRELVARTKALLRRQ--
+----TTVLVVEDEPAIAQAIVHRLTAEGWT-VEAVGDGHAGVAAAARLQPDVVVLDVMLPGIDGLEVCRQIQAE-RPVPVLMLTARDDETDMLVGLGVGADDYMTKPFSMRELVARTKVLLRRT--
+----TTVLVVDDMEASRYAMGSVLSRAGHR-VVPVATGREALAELETRLPDVALVDVGLPDMSGFDLCRLFKEHTAGMPVVHFSAAASPADFCQGLDGGVEAYLKVPAEPLEIEAVVRAAVRNA--
+----TTVLVVDDEADVRDVTARLLTHLGFR-VVVVADGASALQALQEQEIACVLLDANLAGMDAPTTLRELRALAPHIPVVVSSGYSQHEVLQRFAGQTIEGFIQKPYQMSELYGVLQHALRQ---
+----TTVLVVDDDPQILRALRINLAAHGYA-VLLAEDGAAALRRAADGHPDVVVLDLGLPDLHGSEVIEGIRG-WSAVPIIVLSARGDSGDKVRALDAGADDYVTKPFGMAELLARLRAAVRRAA-
+----TTVLVADDHPLWLGALERDLAQAGLDVVATAADGPSTVRRTRATRPDVLVLDLNLPGMRGDEVCRALGDL--ETRVLILSASGEQLDVLAAIKAGATGYLVKSASSEDIVAAVLATAR----
+----TTVLLVDDQPLLRMGFRMVLDQPDLRVVGEAGDGGTAVRLTAELAPDVVLMDVRMPGVDGIEATRRIVASGGASKVLILTTFDLDRYAFAGLRAGASGFLLKDVPPDDLLAGIRTVA-----
+----TTVLLVDDHELVRAGFRRLLEDDKFTVIAEAGSGEQAVQDFNKHHPDVVVMDISMPGIGGVGAIERIIAREPSAKILVLSVHEDSVFTTRAMQAGALGFIPKRSAPEEMLRAVEMVAQ----
+----TTVLLVDDEPNILQALQRLLRRETFR-IVTAASGTEALQLLSQRGVAVILSDMRMPAMNGAEFLKRSREFAPESVRMLLTGYSDISDAVDAVNQGISRYLSKPWNDTDLLQAVRIAVES---
+----TTVLIVEDNDGLRRMIVEVLRASGFQQLIQARDAEEAIELLGAYNPELMILDWNMPGLSGIDLTLLLRQANPRIPVLMLTGRQRSRDVTEARNAGVDEFVIKPFSTRSLMRGVASALSRQ--
+----TTVLIVEDDPMNFRVFSKILTKRGFT-VKGSEDVAEVLALARSKAVDVILIDVSLSRYNGIQITQLLKQATASLPVILVTAHAMVGDRESLLQSGAEGYIAKPVDHQAFVNQIQTM------
+----TTVLIVDDHDLIRKGLRHAFSDPQFEVVAEAGSAGDGLRKAAALQPNVVIMDLRLPDGSGLEATRKLRKAHPSMGIVVLTMYAGDDQLFGALEAGASAFVPKSAPSDDVVSAARHAA-----
+----TTVLIVDDEQDMRNLIEMMLNNSDIE-TYTAASGTEAYDIIVREKIDLVLLDVMMPHEDGFVVCQSIRAM-SNVPIIFLTARDANEDKVKGLTLGGDDYIVKPFTHDELAARIYAVLRRSG-
+----TTVLIVDDDPVQRRLAEAMVRRLGFE-AIVAEGGEAALACLRAAGIDVVLLDLVMPGLDGLGVLAEMRRSAIDTPVIVQTANGSIDAVVTAMRAGAIDFVVKPAGAERLQVSIKNALQ----
+----TTVLIVDDDPVQRRLAEAMVRRLGFE-AAVAEGGEAALAVLRATRVDVVLLDLVMPGLDGLGVLAEMRKAGLDVPVIVQTANGSIDAVVTAMRAGATDFVVKPAGAERLQVSIKNALQ----
+----TTVLIVDDAAFMRMMIKDILSKNGFDVVGEAGDGQQAVDMYKEQSPDLVTMDITMPEMDGITALKEIKTHDPNAKVIMCSAMGQQAMVIDAIQAGAKDFIVKPFQADRVLEAISKTL-----
+----TTVLIIDDDPVQRRLAEAMVRRLGFQ-AQIAENGHDGLNLLRSESVDVVLLDLVMPGMDGLSVLAEMRKSGIDTPVIVQTSNGSIDAVVNAMRAGAVDFVVKPAGAERLQVSIKNALR----
+----TTVLIIDDDPVQRRLAEAMVRRLGFE-PRIAENGHDGLNLLRGGNVDVVLLDLVMPGMDGLSVLSEMRKSGIDTPVIVQTSNGSIDAVVNAMRAGAVDFVVKPAGAERLQVSIKNALR----
+----TTVLIADDQAMVRQGFGALLAQPDISVVGDAPDGKVAVAEAKRLRPDVVLMDVRMPEMNGLDAARAILAADPPVRVLMLTTFDIDDYVYEALSIGASGFLLKDAPAEELVRAVRVVAE----
+----TTVLIADDDPLSRKLLQLHLAPFRFE-VMAASNGQAALELARRRRPKLIIADVLMPGLDGFRLCLALRKRLANVPVLLTVGAPDELDLRMAQNVGANGFVRRTQEGEELIAALLR-------
+--------------------TTVFSLDGHQ-PICAADGQQALELFKQQTPDIVLMDIRMPKISGLEALQIMRQTHQETPVILMTAYAAVETAVEALRLGAFDYVIKPFDLDELKIIIGRAMQ----
+---TTTVLLVDDDPETLAAWAICCAQQGYG-VQSATDGGHALALLDATQIDIVVADWRMPKMSGSALCQAIRNALADTLFILVSGESSPPAFV-----RYDAFLRKPLDYPELFATMRRLLD----
+--TTTRILLADDQDDIRSGFRLILDQPDMTVVGEAADGLRAIEQARLLRPDVLLADVRMPGADGLEVTRVLAG--GPTRVIVVTTFDDDAYVRAALGSGACGFLLKRSGPNLLIEAVRAAMA----
+--TTTNILIVEDEKEIRRFVRIALESEGWR-VFESDTLQRGLIEAGTRKPDLIILDLGLPDGDGLTYIQDLRQ-WSAIPIIVLSARNSEEDKVAALDAGADDYLSKPFGISELLARVRVALRRHS-
+--TTTHVLLVDDNKINLQLLVMFMKKCKFT-YEEAENGQEALDKFTQKRFDYILMDISMPVMNGIEATKRIRQQIQPTTVLALTGLASADARRDVLSAGVDVFLPKPVRFAELKKLLT--------
+---TTSVLLVDDDPMVRNGLRMVLRDPGIVVVGEAGNGRQAVDQARELRPDVVLMDLQMPVMDGVAATRELRGLPDAPAVLVLTTFHLDTYILDALGAGASGYLLKDIPPTEIARAVQMAA-----
+---TTSVLIVEDDPAALSRLVQAVEMHPATVAGCTASAAEALAWLAQHQPDVLLCDLGLPDGSGIDVIRAARERYPACDCMVVTVFGDDHHVLASIEAGAIGYLLKDETTDRIAASIG--------
+--TTSTILVVDDEENILRAIVRLLMENDIN-VLTAGSGSEGLSVLQAHPVALILSDQRMPGMTGAEFLQQAKSLAPEAIRMVLTGYADINATMDAINKGASCYITKPWDDGMLVQTLTEGVQRY--
+---TTSILLVDDQPENLTALRAILADESYR-LVTAASGKDALLRILSEDFAVILLDVRLPDIDGFEVASLVKQRSRHTPIIFLTGATDDAAIYRAYAVGGVDYLLKPLEPEVVQAKVAVFV-----
+---TTSILLMEDEIIIAMDVEDILHGAGFDRIETVSSCRAAEEWLTANDPDLVVMDIELTDGVAGAIARSLRGR--HIPFIVYTGAQR-KVHPDALSFSEGVWLEKPCEPSILLTEVMRCI-----
+---TTSILIADDDXXXXDLVKLYLQNEGYT-IYQAYDGAEVWRLVQEKQPTLVILDIMMPEMNGLEVCRLMRDNGILTPILMLSAKAEDNDKIMGLLTGADDYMVKPFNPLELSVRVKAILRRMQ-
+---TTSILIADDDKEIVDLVKLYLQNEGYT-IYQAYDGAEVWRLVQEKQPTLVILDIMMPEMNGLEVCRLMRDNGILTPILMLSAKAEDNDKIMGLLTGADDYMVKPFNPLELSVRVKAILRRMQ-
+---TTSILIADDDKEIVDLVKLYLQNEGYT-IYQAYDGAEVWRLVQEKQPTLVILDIMMPEMNGLEVC----------------------------------------------------------
+---TTSIIVAEDNSVNRKVILKMLESLGHK-ADAVCDGEELVQQFDPQRHKIVLTDLNMPNLNGIKAAQELRKRGNDFKIYLLTGNVM--ACEEDYSSIIDKVVIKPVSKTNLKHLI---------
+--------------------------------TTSEDGKNGFELALSNQYDFIILDVMLPGMDGLEITKALRREKIDTPILILTAKDEQVDKIIGLEIGADDYLTKPFSPREVLARMKAIFRRL--
+---TTRVVIAEDEALIRLDLREMLEEEGYSVVGEAGDGERAVELAREHRPDLVILDVKMPKLDGISAAERIAEE-RIAPVLMLTAFSQRDLVERARDAGAMAYLVKPFSKSDVVPAIEMAVSRF--
+---TTRVVIAEDEALIRLDLKEMLEEEGYTVVGEAGDGEQAVELAREHRPDLVILDVKMPKLDGISAAEKIAEE-SIAPVLMLTAFSQRDLVERARDAGAMAYLVKPFSKTDVVPAIEMAVSRF--
+---TTRVVIAEDEALIRLDLKEMLEEEGYSVVGEAGDGETAVALAREHRPDLVILDVKMPILDGISAAERIAAD-RIAPVLMLTAFSQRELVDRARDAGAMAYLVKPFSKSDVVPAIEMAVSRF--
+---TTRVVIAEDEALIRLDLKEMLEEEGYSVVGEAGDGETAVALAQEHRPDLVILDVKMPVLDGISAAERIAAD-RIAPVLMLTAFSQRELVERARDAGAMAYLVKPFSKSDVVPAIEMAVSRF--
+---TTRVVIAEDEALIRLDLKEMLEEEGYSVVGEAGDGEQAVELAREHRPDLVILDVKMPKLDGISAAEKIAEE-SIAPVLMLTAFSQRDLVERARDAGAMAYLVKPFSKSDVVPAIEMAVSRF--
+---TTRVLLVEDEEVARKTLSFYLNTIFDE-VVVASDGQEGINFYKERCFDLVLTDIKMPNKDGIEMIDEILEIVPDQKFIIVSAHKNEEDLLKLINLKVLGYFVKPLNVDDMMDMLQKA------
+--TTRSILLADDSPTVLRTMQLILNKLGVV-HHDFINGKHLLDYLFANSIGMIITDLEMPEASGFEVIKQVKAATAHLPIVVNSSMSGSSNEDMARSLNADEFISKS-NPVEIEAAVRRF------
+---TTRLILVDDHPLVRDGLRARLEARNLEVVGEAGNAQEALALAASHEPHLVLMDVGMNGMNGIALAGMFHERFPAIRVLMLSMHDNLQYVTQAVRAGASGYVLKDSPATEIIQAISAVLEG---
+---TTRILVVDDEEDLCEILKFNLEIEGYE-VDTAYSAEEALKK-DLTVYNLLLLDVMMREISGFKMARILRQKTANTPIIFLTAKDTENDMLTGFNLGADDYISKPFSIRQVIARVKAVLRRT--
+---TTRILVVDDEEDLCEILKFNLEIEGYE-VDTAYSAEEALKK-DLTVYNLLLLDVMMGEISGFKMARILRQKTANTPIIFLTAKDTENDMLTGFNLGADDYISKPFSIRQVIARVKAVLRRT--
+---TTRILLVEDDEDDYVIARDVLEEISFLELIRAANVSAAYDYLKQNNFDLCLLDYQLGAFNGIEVLKHARASGFSAPIIMLTGQADSKLDEQALDAGAADYLNKEIGTGRFIRSIRYALARR--
+---TTRILLVDDHPMMRRGLRDLLDEDDLEMVGEAGNGEDAIRLALQIEPDLILMDLNMPGIDGLETTRRMRDADIDARIIMFTVSDEQSHVLEALRNGADGYLLKDMDAEQLIEQIRI-------
+---TTRILLADDHALVRRGVRLILEEPDFEVVAEAGDGAEAVQAARTHRPDLAILDVAMPRMTGLQAARELSQLQPDLRILMLSMYDNEQYFFQALKAGACGYVLKSVADRDLVEACRAAVR----
+---TTRILIVDDDVEIRNLLGGYLSRFGME-AVGVHDGAAMKKALTESSFDLVVLDLMLPGEDGLTLCRSLRGE-SDIPVIMLTARGDPMDRVVGLELGADDYVAKPFEPRELVARIQSILRRA--
+---TTRILILDDDPFILKLLARMLINLGFPSVDCCENGVDALKLLDDTRPDLILLDLNMPGMDGIEFVRYLVERKFTGSLILVSGEDEREKLVQAHKIPILGYLQKPVQPEALRMQLMKLAS----
+---TTRIILADDHTVLRTGLRLLIDQPDFTVVGEAADGEALLALVERVPAEVLVLDLSMPRVSGLECIKELKSRGQEIKILVLTMHGR-EYVKEAMAAGALGYIEKQALDSELFVAIRTVA-----
+---TTRAVIVDDSRFMRTLIRTLLEDGGIDVVAEASDGAAAVETVTEHAPDVVTMDIEMPEMNGIEAVEAIMED-CPTPVLMLSAHAEDDVTFEALDKGAVDFVTKP-------------------
+---TTRALIVDDDVAIRELLCDYLTRFNIQ-ARGVTDGAQMRLALDEEKFDVVVLDLMLPGEDGLSLCRWLRST-SDIPILMLTARCEPTDRIIGLELGADDYMAKPFEPRELVARIQTILRRV--
+---TTRALIVDDDVAIRELLCDYLKRFNIQ-ARGVTDGAQMRLALDEEKFDVVVLDLMLPGEDGLSLCRWLRST-SDIPILMLTARCEPTDRIIGLELGADDYMAKPFEPRELVARIQTILRRV--
+---TTQVALVEDDTGVRERIARVIGDPSLALAYSASNAVDMLRWLGENPVEVLLVDLGLPDLPGLQVIRRCRSMQPACAVMVLSIFGDEANMVLAFEAGASGYLLKDGTEADLATHIRNL------
+--TTQRILIADDEPLFRETTAEFLREEGYE-CLCVEDANDAISVLEEHKFDLILSDLNMPGNLKFELLKEGRTKHSDVPMIVVTGAPSLPSAIESVRLGVTDYLLKPVKLEELLTAVQRSLSQA--
+--TTQRILIADDEPLFRETTAEFLREEGYE-CLCVEDANDAISILEEHKFDLILSDLNMPGNLKFELLKEGRTKHSDVPMIVVTGAPSLPSAIESVRLGVTDYLLKPVKLEELLTAVQRSLSQA--
+---TTQILIVDDDQELRDLLRDYLVRQGME-VSVLHDAATLEKRLERERPDLIVLDLMMPGVDGLTALRQLRAAGDDIPVIMLTARADDVDRIVGLELGADDYLGKPFNPRELLARVQAVLRRR--
+---TTQILIVDDDQELRDLLRDYLVRQGIE-VSVLHDAASLEKRLERERPDLIVLDLMMPGVDGLTALRQLRAAGDDIPVIMLTARADDVDRIVGLELGADDYLGKPFNPRELLARAQAVLRRR--
+---TTQILIIEDEPLIAMDIEQMVESLGHKVVGVARTSEEAMAMFQQKRPRMILADIQLASSSGIDTVNDILKN-ECIPVIFITAFP--ERLLTGERPEPTFLVSKPFNPDMVKALISQAL-----
+--TTPTVLVIDDVAEIVEELLTLLSLREIS-ATGAHSLDGAIGALENAQIRVIACDVRLGKESGFDICDRIRTKARNFAYIFISGD--PMRLNQASHLPKHSILTKPVEPRALIELLREKLDA---
+--TTPTVFIVDDDPAVLDSLAMLITAQGMK-TVTFPNAMEFLDGYQGNQICCLVLDIRMPQITGLALQEQLMERNISIPIVFITGHGDIEQCRRAFQTGAIDFLTKPIDQNRLIASLRRGI-----
+--TTPKVLLIDERKTSVERIQKMLRDRA-D-LDVTHDPHAGFFQAAETSYECVMISTAFADFDPLRLCSQLRSRTRFVPIILLAEEGEEERIIRGLELGINDYLMRPIDQQELTARLRTQVRRK--
+--TTPKVLLIDERKSSVERIQKMLRDRA-D-LDVIGDPHAGFFQAAETSYECVMISTAFADFDPLRLCSQLRSRTRFVPIILLAEEGEEERIIRGLELGINDYLMRPIDQQELTARLRTQVRRK--
+--TTPCILIVDDEPLNIRLLDIVLKKNGYR-TLSCTSGPEARALAAEHSPDLILLDVLMPDEDGYATCALLKQQTSDIPIIFISALTDTSSKVRGLEVGGVDFISKPFEKAEVLARVKVHL-----
+---TTNILLVEDDRVDVMNVQRSFKQANIAPLYVASNGVDALAILKGEHRRLVLLDLNMPKMSGLELLQNIRKSLRSTPVIVLTTSNQEKDRMEAYDLNVAGYLLKPVTFGSFFELITTLN-----
+--TTMRVLLADDASVNGTILREQLDVLGCA-VHVVGLAGAALDLLYRSDWDLLLIGTDLPDMAACALAEAVHARGMPCSVAIVTTHLAPDDARRCAAANVQSVLTKPVTLVRLRSVLAAVARRRG-
+--TTMRVLLADDASVNGTILREQLDALGCA-VHVVGLAGAALDLLYRSDWDLLLIGTDLPDMAACALAEAVHARGMPCSVAIVTTHLAPDEARRCAAANVYSILTKPVTLGRLRGVLSGVARRRG-
+--TTMNTVLIEAHPLVRTGIAHLLRTLGVTGVTVVEPDEGMFDAIETNDAGLLVIGLPLPHLDELSAIGEIMHRPHARHVVVLAESESPDIIRTLMQMGLSGYTLKHSPGEVIAASL---------
+--TTMKVLVAEDELVTRLMVQVSLENWGYD-VLEAKDGKEAMELFGREAPRIAIIDWEMPEVDGLEVCKRLREQESENPIILLTAHGSKNDILLGFDAGADDYITKPFNSDELRARVRV-------
+---TTMIWVVDDDPELRQMVGTYLIDQGYE-VRCLSDVKQFEARLDFQRPDLVVLDLMMPGDDGLTALRRLRDADDDLPVVMLTAKGDGIDRIIGLEQGADDYLAKPFLPRELSARIEAVLRRR--
+--TTMHVLLADDASVNGTILREQLDVLGCA-VHVVGLAGAALDLLYRSDWDLLLIGTDLPDMAACALAEAVHARGMPCSVAIVTTHLAPDDARRCAAANVQSVLTKPVTLVRLRSVLAGVARRRG-
+---TTLVYVVDDDAGMLESTQWLLESVGLA-VEAYSDGRKFLDSMTAQSNGCVVLDIRMPGLGGLNVQEELQKRGLALPIIFVSGHADVPIVVRAFKSGAFDFIEKPFNEQLLLDSVQQALQER--
+----TTLVLVDDEPSLREPLAEYLTGQGFV-VREAESAAAARSLLGSEAPDLVLLDIMMPGEDGLSLCRHLVET-RHLPVILLTAKGEAMDRIIGLEIGADDYVTKPFEPRELVARIRSVLRRA--
+--TTLSVLVVEDNEDINNYITSLLDD-KYR-IYQASNGEEGIKIAKEILPSLIISDIMMPIKDGFEFSQEIRSSTAHIPIIFLTAKAEDIDIIHATHIGIDDYLTKPFNSEILKAKVDNLISQR--
+--TTLSVLIVDDNASVRKALYEAGRSFGWH-TACASGAGQARALLIERPYDLLLLDQDMPGTDGPALLQQLPPELALPPVLMMTSEHRAAIAQQTATLGLAGVLAKPVSPARLLERVSALLA----
+---------------------------------------TTLSALSQSKIDGILLELGSPHTPSLQLLSQLKKQ-TNAPIIVIDGGD-TEIAVQAFKNGADDYLIKHTTPDDLCLAMRTAIENA--
+--TTLRILYIEDNPANMQLMANIIETLGCE-LVIAPNAEDGITKAQQFLPNIIFIDINLPGMNGDEALPILKAEAQNTLFYALTANAMKEDVKKGLIQGFDKYLTKPINVAEILSIIKE-------
+--TTLRILLVEDDLPMAQALQEALGRHGLL-VDCVHSLAAAGATLRLNVHDLLILDRGLPDGDGVGFIATARRLCPALPIVLLTARGEIAERVDGLDGGADDYLVKPVAVDELLARVRAIARR---
+----TTLMIVDGHELIRHGVRQILEEQDLSVVAEAGDSVTAVTVSTAVRPDVVVLDIEIPGGDPVGTVRRIREGSPDTAVIILSMLDGPELVRDLLEVGVRGYLHKSVARHDLVSAVRAVSRDR--
+----TTLMIVDGHDLIRHGVRQILEEQDLSVVAEAGDSVTAVTVSMAVRPDVVVLDIEIPGGDPVGTVRRIREGSPDTAVIILSMLDGPELVRDLLEVGVRGYLHKSVARHDLVSAVRAVSRDR--
+----TTLLVVEDDEAILHLIDVALTMNYYK-VVTAKTGKEADFRLRTEQPDIILLDLGLPDIDGLSLIQQFRD-FVDTPIIVISARTEEQTIVEVLDRGANDYMTKPFNIDELRARIRVALRM---
+----TTLLVVEDDEAILHLIDVALTMNYYK-VVTAKTGKEADFRLRTEQPDIILLDLGLPDIDGLSLIQQFRD-FVDTPIIVISARTEEQTIVEALDRGANDYMTKPFNIDELRARIRVALRM---
+----TTLLVIEDDDAISHLIDVALTMNYYK-VIKAKVGKEANFRIRTEHPDIILLDLGLPDIDGLKLIQQIRE-YVDTPIIVISARTEEETIVKALDYGANDYMTKPFNIDELKARIRVALR----
+----TTLLLVEDEAALADSLTTEFELENMS-VIWAKDGAEALTLFKNNKINVIILDWMLPKLDGFSVLRKIRQS-SQVPIIMLTARDYIGDKVAGLTGGADDYITKPFEMEELVARVEVALRHN--
+----TTLLLIDDDPNLILLVRDYLEFRGYD-MLTAANGVEGLQILEETTPDLIICDVMMPEMDGYTFIQNVRQQISWIPVIFLSAKGQTCDRIEGLNQGADVYLVKPFEPEELVAQVESSLNQA--
+----TTLLIVEDDREIRSLLADFLGREGYD-TRLAADGRAMDAILAGIRPDLVILDIMLPGEDGLSLCRRLRAQ-GDVPVLMLTAKGDEVDRIVGLEVGADDYLVKPFNPRELLARIRAILRRV--
+----TTLLIVEDDPVSRKILSAAAEDEGFV-VHACPDAESGWEFFQQQQPWIVVLDWRLGGLNGVGLARKIRDSGHYVTILMVTVQERPEDMEEALKAGVTYYMTKPVKRDYFQAWL---------
+----TTLLIVEDDPVSRKILSAAAEDEGFV-VHACPDAESGWEFFQQQQPWIVVLDWRLGGLDGVGLARKIRASGRYVTILMVTVQERPEDMEEALKAGVTYYMTKPVKRDYFQAWL---------
+----TTLLIVDDNPDDRLTFKRYLNRYEYQ-IIEASSASEGLELVKTFDIDGILLDFRLPDEDGLEFIQQLKQHNNSCPIIMLTGVGNQSVAVEAMKNGVHDYLVKDITPDNLHKAIQNSLEKF--
+----TTLLIADDHPLFREALRGAVQRVGVQ-LLEADNVDALYTLADAQPADLLLMDLNMPGAQGFSALVHMRSLHPQLPVVVVSAREEPTVMRRAIDHGAFGFIPKSADSDTIGRALATVLD----
+----TTLLIADDHPLFREALRGAVQRVGVE-LFEADNVDALYTLADAQPADLLLMDLNMPGAQGFSALVHMRSLHPQLPVVVVSAREEPTVMRRAIDHGAFGFIPKSADSDTIGRALATVLD----
+----TTLLIADAHPWTRLGLSALLNAVGLSVVAQAADSETACALAESAEPDIVIIDTDFPDLGGAETIQRILEADPENPALLVTSTVDDNDIYAALHAGARGILLKNIPPEQMTAAVTAAAR----
+--TTLKILVAEDNRTNQKVALRLLELLGYR-ADVVNTGIEVLTALEHQRYDVILMDMRMPEMDGVEATQRIRHHHKETWIIAMTANTMDSDRELCLSVGMDDYLCKPIKRDALELALE--------
+--TTLKILLVEDYEDNRFLMLMLLETLGYQ-ADWVTNGQEFLDQTEEQDYDIVFLDCQMPILDGYEAIKRFRQEGNHTVVIGLTAHAMEGDRDKCLEAGMDDYLSKPILIESLANLLEK-------
+-------------------------------TTLIEGCLSLLQHAIDDKPSLILFDVEVPVEEALCRLGELRA-ARFIRKVILTSHSDLDDKVDALEAGADDFLEKPISTRELIARIDAVLRSS--
+----TTLALVDDDENIVASLKMFFEAEGYQ-VRAYHDGESALPALTDSPPDIAILDIKMPKMDGMELLRRLRQT-SELPVIFLTSKDEEIDEVIGFNIGADDFVRKPCSNRLLAERVKAVLRRS--
+---TTKVLVVEDSVTSRNYICSLLKKFQFQ-IYEASDGLEALNLLAEHQIRMVISDHRMPNMDGYELIKAIRHRMQDLIFIGLSGTNDGVLSSKFIKSGANDFLSKPFYHEEFFCRVMQNLEA---
+---TTKVLVVEDSRTSRNHICSLLRKFQFQ-VHEANDGLEALEELDNHRIKMVIADHRMPNMDGYELVKAIRHRMQDLVFIGLSANGDSVLTSKFIKSGANDFLSKPFYHEEFYCRIMQNLESQ--
+---TTKVLVVEDSKTSRNHICSLLRKFQFQ-VHEANDGLEALEVLDNHRIKMVIADHRMPNMDGYELVRTIRHRLQDLVFIGLSASGDSVLTSKFIKSGANDFLSKPFYHEEFYCRIMQNLESQ--
+--TTKTVMVVDDSVTVRKVTTRFLEREGFN-VITAKDGVDALRVLQDDDPDLMLLDIEMPRMDGFEVAKNIRSRLRHLPIIMITSRTGDKHRERAMSLGVNKYLGKPYQEELLLSSIAELLEEA--
+--TTKTIMVVDDSITVRKVTTRLLKRHGME-VMTAKDGLDAIAQLQERIPDLMLLDIEMPRMDGYELATQVRNDWEHLPIIMITSRTGTKHRDKAEQIGVNRYLGKPFNENELLKNIQGLLV----
+--TTKSILLADDSPTVLRTMQLILNKLGVI-HHDFINGKHLLDYLFSNSIGMIITDLEMPEASGFEVIKQVKSATAHLPIVVNSSMSGSSNEDMARSLDADEFISKS-NPVEIEAAVRKF------
+--TTKNILLIEDEDPVRIFATKALVKKGFN-VIDINCGDKAIDIIKNQNIDIVISDVVMPKISGPEIIDQILKIQPNIKVIFISGYAEEFNKHSNIDASKINFLSKPFTLKQLTEKVSEIL-----
+--TTKKVIFADDSRFIRKMVVELFHALNVN-YVMYTNGKELIDGIKNDEIGLFITDLEMPVMGGREVMKFIRDSYDSIKIIVHTNMSNDSMKENLATAGADKIIGK-VNMLKLGEAIHEL------
+--TTKKILVYSDNSDVRESVKRAVGKVGHTSVEGATPDGTILKIREAEPFDLLILDAETPKLGGIGLGKMVRDENEEIPYIVLIARPQDEWLARVA--RPEAILNYPTDLPQLTTSVESL------
+---TTKIVIIDDHQLFREGVKRILDETNFHVVAEGDDGEEALELMEKHDPDVIIMDINMPKVNGVEATRRLVEANAEAKVIVLSIHDDENYVTHALQTGARGYLLKEMDADALVDAVKVVA-----
+---TTKILYIEDNRDNQRLVERVLGARGYH-VLIAEDGPSGISLARESHPALILVDLGLPGLDGYETTTRLRSHLTGIPIIALTADASNEAREQALVAGCDGYLTKPIDTRQLPNQIAEFL-----
+----TTIVVADDQAMIRAGLVALLSEPDLRVLAEAADGQAAVAAVQRRRPDVVLMDVRMPGVDGITAAREIVDTDGQTSVIMLTVHDLDEYVYAALRAGASGFLLKDAPPEELVRAVHTVA-----
+----TTIVLADDHPIFRDGLRKTLDDSGFKVLAAGCDAEEAVRLTREHRPDLVILDLSMPG-GGLGATRQIAALGDAPRIAILTVSEDSNDVADALEAGATGYILKGVTASALTKSLRSIAK----
+----TTIVCVENDPAILDGMKTLLRGWDAN-VIASVDPKQACRAIASEPITGLLVDYHLDRGNGIAAIRDIRHKGAHIPAILITADRSPPVREAARAYGI-VVLNKPVKPATLRALLSQWRNQ---
+----TTIVCVENDPAILDGMKTLLRGWDAN-VIASIDPKQACRAIASSGITGLLVDYHLDRGNGIAAIRDLRHKGANIPAILITADRSPGVREAARSYGI-IVLNKPVKPATLRALLSQWRA----
+--TTIRVLYIDDEENNLHAFKASFRR-QYE-IYTALSAVEGLKILENVPVQVIIADQKMPNTTGVEFFKSIKNTFPDPTRILLTGYTDIEALADAINHGIYRYITKPWNDLELHNSIKNAYD----
+--TTIRVLLVDDQELVRAGFRMLIDQPDLSVVGEAGDGQEAVAALTHTEADVVLMDVRMPRMDGVEATGLIAGREGAPRVIVLTTFDLDEYAFAAIRAGAAAFLLKDARPEDLLTAIRTVH-----
+--TTIRVLLADDQALLRSAFKVLVDESDMEVVGEASDGAQAYALARERGADVVLMDIRMPGTDGLAATRMISAELAGVRVVMLTTFEVDEYVVQSLRAGASGFLGKGAEPEELLNAIRVAA-----
+--TTIRVLIADDQMMVRQGFTVLLNEPDIEVVGQAVDGADAIDQVAELAPDVVLMDIRMPGVGGIEATRRLTEAGATVKILVLTTFDLDEYVYEALRAGASGFLLKDASADELAHAVRVVA-----
+--TTIRVLIADDHAIFRQGLATIINDPEMQVIAQAENGEQAIALFGEHQPDVTLMDLRMPEVEGVAAIGAICALVKSARIIVLTTYDSDEDIYRGLQAGAKGYLLKDTEPDELLNAIRTVHR----
+--TTIRVLIADDHAIFRQGLATIINDPEMQVIAQAENGEQAIAAFREHQPDVTLMDLRMPEVEGVAAIGAICATAKSARIIVLTTYDSDEDIYRGLQAGAKGYLLKETEPDELLNAIRTVHR----
+--TTIRVLIADDHAIFRQGLATIINDPDMQVIAQAENGEQAIALFEEHQPDVTLMDLRMPEVEGVAAISAICAIVKFARIIVLTTYDSDEDIYRGLQAGAKGYLLKETEPDELLNAIRTVHR----
+--TTIRVFLVDDHLVVRAGLRALLNQPDVEVVGEASSGEGAATAIPSASPDLVMMDLDMGGMHGAEAIKRLRSDGVDVPVLVFTTYDTDADVVRAVDAGAIGYLLKDSTPDEIFGAVRGAVA----
+--TTIRILLADDHALVRRGVRLILDREDLEVVAEAGDGAEAIAMARTHEVDLAVLDIAMPRFTGLQAARELAAVRPGVRILMLTMHDNEQYLFQALKAGASGYVLKSVADRDLVAACRAAMRD---
+-----------------------------------TTIRDALTGIRQNAFILTLTGVETRDEAQLRLISTLRATTRHCGILVLQSRPHPAGAAHALDLGADDLMQHGFDIDELSLRLTGLLARK--
+----TTIMIVEDEWAIARVLDAYCKKRGWH-TVMVEDGHQVMAVFLDASPDLVLLDVMLPGRDGWSILSEIRER-SDCPVVMLTALDELDDRLKGFDGGADDYIAKPFHGEEVVARIAAVLKRQ--
+----TTILYIDDEPLVADASVRFLTHSGFE-VDKALSGREALEKLRAGRYDAVISDYHMPGMTGIELLKIIRSDIGDIPFILFTGKGREEVVIEAIEHGVDYYVQKGGTPG---------------
+----TTILVVEDEPAIQELISVNLSFAGHK-VLRAFDAEQAQTLIRAELPDLILLDWMLPGASGITLARTLRSRTRHVPVIMLTAKGAEHDKVEGLEAGADDYITKPFSPKELIARIKAVLRRR--
+----TTILVVDDSKSMRRIIVDSLKDEGYE-CRSAEDVDTALIALDGCEFSLVLCDIEMPGRNGIFLLNEIRTTRPDTYVVMLTGVTDPETVMHCIHLGANDYLMKPFTLERLLLTVRNALQQR--
+----TTILVVDDIEPNIKLLTAKLLQEYYT-VLTANSGKEALAILKKEKIDIILLDVMMPEIDGFEVCKTIKTATTHIPVVMVTALSDIDDRVKGLEAGADEFLTKPINDTALFVRLKSLSRM---
+----TTILVVDDHPLLLSGLGMLLNEEDLEVVGQTDRAESALTLAGELEPDIILLDITLSDTSGIDLLPRLLEITPQSQVIMLTMHENQRYLQLAMQAGARGFVLKKGLDADLLYAVRTVYR----
+----TTILVIDDSVTVRRTLQRVLGG-SFR-LIQCRDGKEAWDLLNRQNIDLALCDIEMPNMDGFSLLQLVRAHWHSLTVVMLTSRENPLHRNRAKALGADGYLTKPFQPNQLLSTIDQFLAES--
+----TTILLVDDHPVVREGYRRLLEQPGLSVIAEADTAAEAYRLYKAHAPALVILDLSLPGPSGIEAIRHIRQWDRQARILVFTMRQGAALAAKAFEAGAAGYVTKASPPRELVEAVGTVMR----
+----TTILLAEDDAVSRILIKRSLQEENLT-ILDAWNGRDAVQMIMQHPIDLVLMDIKMPVMNGFEASREIKKLRPELPIIAQTAFTSKEERLKALEAGCDSFMSKPINKQKLIELIRLLLH----
+----TTILIVEDEQDLLDTLEFNLQREGYA-TRRAASGRAGLEAAALEPPDLVLLDLMLPDISGTEVCRQLRARTRSVPVVMLTARGEEVDRVVGFEVGADDYVTKPFSVRELMLRVRAILRRAG-
+----TTILIVEDEPSIAELIAFTLKEAGWS-SFVVSNAAAAWDFVQHRAPQLVLLDWMLPDRSGLHLLSRIRAQLQQLSVIMLTAKSMEEDKIAGLDNGADDYITKPFSPRELTARIKALLRRK--
+----TTILIVEDEFLIAVEMEAVVHDLGHESAGIADDMQSALAKAS-DAIDVALVDVNLAGATGPRIGEKLAAD-FGIEVIFVTANP--AQLGEGV-SGTLGALEKPVDLSILKQVLDYVI-----
+----TTILIVEDDRNLAGLLKYNLEKAGYS-CLHAATGEEALEQLRQHAVNMVLLDIMLPGIDGFEVCRRIRQQWSDLPIVMLTAKGEEIDKVFGFELGIDDYVVKPFSPRELNLRIRAILKRD--
+----TTILIVDDHPPVRAVLKTHFSQLGITHVLEADNGQAAIEIVRQYLPDVVILDLDIPKINGLDVIPRLKASHPAVRILVISGQDQNAFAPRARHAGAHGFVSKTQELAEIVRCTESVLA----
+----TTILIAEDSRVQRKILDNHLQTLGYN-VLSASDGVEALEIFRAIQPRVVITDLEMPNMDGFELIRQIRKHIQYTHITVLSSLAEKENIIRAISLGASDYLVKPFHPDEMRVRLE--------
+----TTILIADDDSNIRELLRFILQREGFR-ALEAADGEEASRVMRQEDVALAIVDVMMPEKDGLMLCEEIRRD-YDIPVMLLTARGELDDKARGFRSGTDDYMVKPFEPDELLYRVRALLRRY--
+----TTILIADDDAVQRRLVENMVQKCGYR-TVVVDSGDAAIETLTADDIDAVVLDLVMPGLDGMGVLERMRDAGLSIPVIVQTAHGGIDNVVSAMRAGATDFVVKPVGIERLQISLRNALNAS--
+----TTILAIEDDPVLGAYLQEELQRGGCQ-VTWCRNGLEGLETAGRQAFDVVLMDILLPGLDGLDALAQLRRH-SATPVIMMSALGAEADRISGFQRGADDYLPKPFSMAELQVRIEAILRRVA-
+--TTIHVLVVEDHEDDFRYLAFLLGRSGYH-LSWASSYAAGQAMLRQGGFDVGLFDYRLGGGTGLDLLREAHETGCTIPIILLTGHDSAEVDQEASQAGAADYLCKTLTGTELERTIRYAMRHAA-
+----TTIFYVDDDEDDRMFFEEVTQQIGEK-ISLFEFGDQMLLQLENPPPSVIFVDLNMPIKDGFEVLQEIKKNLKNIPVIILSTTNNSDTVNRCLDLGASLYVQKSISLKDLKKSLEYVI-----
+--TTHTLLLVEDDPADAHLVRLACEECGNSCIHHVKDGLEALDFLERRPPDLVFLDLNMPRMSGVDFLREIDRQFKQIPIVVLTTSDAGTDVDTAFSLGCRGFITKPMDMEQLCYQIR--------
+--TTHTLLLVEDDPADAHLVRLACEECGCR-IHHVKDGLEALDFLERRPPDLVFLDLNMPRMSGVDFLREIGRQFKQIPIVVLTTSDAGTDVDTAFSLGCRGFITKPMDMEQLCYQIR--------
+---TTHLVIADDHPLFRNALRQAVTSVLAEVVDEAGSFEDLTTLLEKDEVDLVLLDLTMPGISGFSGLIYLRAQYPAIPVVIVSASDDGATIRRSLDFGASGFIPKRFGVDTLRDAITKVMD----
+---TTHLLLAEDEAALGQIVKESLETRKFT-VDLAEDGEKALKLFEQKSYDALVLDVMMPKKDGFTLAKEIRAKDDSIPIIFLTAKSQTSDVVEGFSIGGNDYLKKPFSMEELIVRIHNLVARK--
+---TTHILVVEDDPAIGRLLLMHLREAGWQ-AILANTGMTGLRLWASDCFQIVLLDVMLPDLSGWELCQQLRAE-SNVPILMLTAKASDDDVVRGLNLGADDYLTKPFSQAQLIARVQRLIQRQA-
+---TTGILVASDQILLRAGLRELLHEPNLDVVGEALDENETIYLTGRLEPDIVLMVVLNRREASIGVTKRLKAQHPDIGVILVTSCEDTTFARDIIRAGASGYLPTRAAQSELINAIHAI------
+--TTFTVLCVDDEVNILKAIKRVLHRQDFK-LITAESGAQALEILKQESVQVIVSDMRMPNMSGAEFLQKSTEIIPDCYRILLTGYSDMSSTIDAVNKGIDRYLQKPWDNHELITTVNDGLAKI--
+--TTFEVLLVEDDNELAELIQDFLQCYEFN-ITIVTDGITAVKTILDQQPDLVILDIMLPGQSGMEVCRAVRSQ-YSGMILMQTALDDDIDQVMGLELGADDYVVKQIKPRLLLSRIRALLRRQ--
+-----------------------------------------------TTFDVLIVNISLS-KDLLRLCSAIKSKTRSIPIIAIVDDEDESLITEITELGINDYICVPVNKSEFIARVTTQVKRK--
+--TTATILVADDDRGIRTVLSQALGRAGYE-VRTTGNASTLWRWVSEGEGDLVITDVVMPDESGLDLLPRMKKIRPELRIIVMSAQNTLLTAVKATQRGAFEYLPKPFDLKELVNVVGRALS----
+--TTATILIVEDDPDVRQAVSLWLTASGYA-VATADDGRTGLAAIREHKPDAVLLDLRLPGLDGFDVLKALAREGKPPPVIVISGQDEIQGVIQAFRLGAADYLQKPVSFDLLGHALEAVLERQ--
+----TTALVVDDSKVSRNAFRTDLEKLRIN-VLEAEDGKEALAIMDNNNISLILTDYNMPNMDGVELTIKLRQKKDVLSIIALSASEELNILSDFIKEGANDFISKPHKFEELNVRVHSNLD----
+----TTALVADDMPLARAMLSNILLAQGIGRVIVVEDGKKAISRFLADAPNLVLLDIDMPKLDGLEALRQIKECSPGVFACLVSSNSTRVNVQLAREFGVDGFLVKPYTPLNLKRILARY------
+--TTAKVLVVEDEKALSADIVELIEPI-CE-TTTAFDGEQGEFLASQGVFDAIILDLMLPGESGLDLLLHIRNQGVKTPVLILTAKDTIADKLRGFNDGADDYVTKPFHREELLARMKALLKRTG-
+--TTAKLLIVDDLPENLLALDALIQGEDRE-VHQAQSAEAALSLLLEHEFALAILDVQMPGMNGFELAELMRGKTKHIPIVFVSAAGRENYAFKGYESGAVDFLHKPLDTLAVKSKVSV-------
+--TSYTILVVDDNSDLTDFFSKALSEYFKK-VLIASDGVEALQLVKSYTPDIIVSDVMMPRMNGYELCKGLKEAVSHIPIILLTARDDKESQISGYKNGADGYLTKPFEIEMLMELIRNRLKN---
+--TSYTILVVDDNSDLTDFFSKALSEYFKK-VLIASDGVEALQLVKSYTPDIIVSDVMMPRMNGYELCKGIKEAVSHIPIILLTARDDKESQISGYKNGADGYLTKPFEIEMLMELIRNRLKN---
+--TSYSVLAVDDEPSIGKLLEKELSTPARA-VHVAGSARQARERLRRATYEVVVLDIRLPDADGIEFMVELRQRYPDMEVILITGHGNIDNAVEAMKLGAYDYITKPFNLTELEVVVERAYQRA--
+--TSYRILMVDDELPVLLTIKRRLRM-HFD-IVSVLSPTEALQRIATKPFDIVISDMRMPEMSGIEFLSRVRKIDPSIARIMLTGDLDRETLLQAVKAEVSKFLEKPVSSDQLCEAIMETAAE---
+--TSYRFIIADDHPLFRGALRQTLETQYPDVIEEAGALEDVTARLEQGEVDLILLDLSMPGMRGFSGLMYLRAQYSGVPVVVVSANEDPQAIRRAVEFGASGFIPKSHGIDVIREAISEVMS----
+--TSYKILLAEDNLVNQKLAVKILENHGHS-VEVVENGQEAVEAVKKNHYDVILMDVQMPIMGGFEATAKIREE-KRTPIVALTAHAMLGDRERCLKAQMDEYLSKPLKPSLLLQTISKCIHNM--
+--TSYHILVVEDDPVGRQTLAAYLVKDNHR-VSEAGDGEEMRRIFARGDVDVILLDINLPGEDGLSLLRELRRQ-SEVGVIMVTSRREDVDRIVALELGADDYVTKPYNMREILPRTRNLARRVT-
+--TSYHILVVEDDPVGRQTLAAYLVKDNHR-VSEAGDGEEMRRIFARGDVDVILFDINLTGRRTGSLLRELRRQ-SEVGVIMVTSRREDVDRIVALELGADDYVTKPYNMREILPRTRNLARRVT-
+--TSVRLLLVDDDPSLLKLLGMRLRSEGFT-VVTAGSGPEALRVLNRENFDLTISDLRMDEMDGMTLFVEIQKLKPGMPVIILTAHGSIPDAVAATRQGVFSFLTKPVDRDALYKAIDEALAH---
+----TSVMIVEDEPIIAADIESLVESMGHEVTGIATTRSEAIELAKKQTPGLILCDIQLADSSGIDAVHDILGE-IDVPVIFVTAFP--ERLLTGEKPEPTYLVSKPFQENTLIATIGQAL-----
+----TSVMIVDDHEVVRRGIADMVDAAGLRVVAEAGSVADAVRRGTLTRPEVALVDLQLPDGTGIEVIRRLADESSDTRCVVLTSFDDDDALASAIEVGARAYVLKTVRGAEIVDVVRAVA-----
+----TSVLVVEDNVEVGTFATQTLAELGFG-TVWAANAAEALAELAKDSFDVVFTDVMMPGMNGVDLAREIQRLHPDLPVVLTSGYS---HVLARTGTNGFELLQKPYSVEQLSRTLQAVAK----
+----TSVLVVEDNVEVGTFATQTLAELGFG-TVWAANAAEALAELAKDRFDVVFTDVMMPGMNGVDLAREIQRLHPDLPVVLTSGYS---HVLARTGTNGFELLQKPYSVEQLSRTLQAVAK----
+----TSVLVVEDNKINRQIAKELLEGVGVR-VTLAGDGLEALALVENYDFDLIFMDIQMPRMDGLEACRRIRQHKKQPPVVAMTAHALAGDRETSLRAGMNDHITKPIDPDELYAALANWIKRN--
+----TSVLVVEDDVAIRDMLSFTLKQAGFG-CDSVGDGEAGLDFLKKQQPDMILLDWMLPGIDGIEFIRRLRANLANIPVIMLTAKGESEDMVKGLAVGADDYVNKPFSPPELMARIRAVLRRC--
+----TSVLVVDDNAENRVLLSGLLKPH-HR-VLVATGGVQAINICKQKKPDIVLLDVMMPEMDGYEVCERLTSETHDIPVIFLTAKSQIEDEQRGFAAGAVDYILKPISPPILISRINTHLR----
+----TSVLVVDDEPAIHRFMAPALAANGYD-ALRADTGTQALALVVNRRPDIVVLDLGLPDMDGKEVIRRLRE-WSDVPIVVLSARDREIEKIEALDLGADDFVNKPFGIGELMARLRAALRHR--
+----TSVLVVDDDKTTRTLMKRMLERMGCT-VTVAENGAVALKLMGEVRFDVVFMDNQMPLVSGMGVARRLRAIGRDDFLVGVTGNALQTDQREYLDAGVNRLLTKPVLEKNMREML---------
+----TSVLVLEDNVDDYLLLSIAVKKTALPILHWVHSPSEALAYLHGEGPCLFLTDLNIRTYSGLELIQKIRQRYKDLYIAVLSGSLDEHQIILVYEAGGTVFLNKTSAMNELISMMHGLLAQ---
+----TSVLVISTNPALVDGAQAYADNNKLH-IEFCSNTRDALNLAQQHAFSVAIDDGSSDDGHLFEASQKLQASMPDLTLIIAENDTESISPRELVRLQAYSYLEKPFRKSALKQAIDAAIEA---
+----TSVLVIDDEPELAEYTAKYFNMSGVE-TQYVLTAQDARDFLKKNTCSLILLDINLGNDSGFDLCSEIRT-CMDVPIFFISARAAEDDMLLALSIGGDDYICKPYSLGVLLAKVRAVLKRY--
+----TSVLVIDDEFEIRTVLERVISKEGYQ-VLSAKDSDSALEIIRNQKVDVVISDIVMNGKSGIEVVKEIRKINENIPVILMTGNPDLNSAEEAVRNRAFDYISKPIRRRNILEILERA------
+----TSVLVIDDEFEIRIVLERVISKEGYQ-VLSAKDSDSALEIIRNQKVDVVISDIVMNGKSGIEVVKEIRKINENIPVILMTGNPDLNSAEEAVRNRAFDYISKPIRRRNILEILERA------
+----TSVLVCDDSKLARRQLARSLEDWDIK-VEFAINGVDCIKQIKAVDPEILFLDLNMPEMDGYEVLMAMKELGLNVLTVVVSGDIQPNAHQRVLDLGAIDFIQKPCSPEKLAEIIEH-------
+----TSVLLADDDARLRQFLELELREEGYA-VHSCGDGIGALTQIRQEPPDLLVLDWMLPDLSGVEVCQRLRSTGVQVPVLMLTGRDAVKDRVEALDAGADDYLVKPFSIEELLARLRALARR---
+----TSVLIVEDEPSILELISYTCRTSGME-VRKAANVAEAKKNLEAAKPDIILLDWMLPDCAGLDWLRELRSSNESLPVIMLTARGQEDDRVRGLEAGADDYVTKPFSPRELVARIRAVIRRKG-
+----TSVLIVEDEESLADPLTFLLRKEGFE-ATVVTDGPAALAEFDRAGADIVLLDLMLPGMSGTDVCKQLRAR-SSVPVIMVTARDSEIDKVVGLELGADD------------------------
+----TSVLIVEDEESLADPLAFLLRKEGFE-ATVVTDGPAALAEFDRAGADIVLLDLMLPGMSGTDVCKQLRAR-SSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRG--
+----TSVLIVEDEESLADPLAFLLRKEGFE-ATVVTDGPAALAEFDRAGADIVLLDLMLPGMSGTDVCKQLRAR-SSVPVIMVTARDSEIDKVVGLELGADD------------------------
+----TSVLIIEDEPIISMDLEQIVRDLGHDIMATVVTREEAVSAISKNKPGLVLADIQLAGSSGIDAVKDIFAR-FRVPVIFITAYP--ERLLTGERPEPTFLITKPFLPSTVKAAIGQAL-----
+----TSVLIIEDEPIIAADLANLVEDLGHTFAGNAATRKHAVELARRVKPGLILCDVQLANSSGIDAVQDILAD-FDLPVIFITAFP--ERLLTGERPEPTYLITKPFQDDTVKAAISQAL-----
+----TSVLICDDSKLARRQLARSLPDWDIK-VEFACDGVDCIKQITKAQPEILFLDLNMPEMDGYGVLAAMKEQGLDVLTVVVSGDIQPSAHQRVLELGAIDFIQKPCSPEKLAAIIEH-------
+----TSVLICDDSKLARRQLARSLPDWDIK-IEFAHDGVDCINQIKKIQPEILFLDLNMPEMDGYEVLIAIRELGLNVLTVVVSGDIQPAAHERVLELGAIDFIQKPCSAEKLATIIEH-------
+----TSVLICDDSGFARRQMARSIPGWDVD-IHFAENGKEAISAIKQGKADVMFLDLNMPVMDGYQTMQIVKEQDLPTLVIVVSGDVQPEAHKKMLSLGVIAFIAKPIDNQKLCEILRQ-------
+----TSVLAVDDVPDNLEVIARVLRNRGAT-VTTALSAAEAIKTLETTKYHVLVSDIAMPEMDGFDLIAATRRHCGHLPAIALTAFARQEDGDRALAAGFDHFLSKPVDPVELVAAICRCT-----
+----TSVLAVDDDRVHAYAMEKKLRASGFV-VKCVHSGPEALAELRSGKYDAILLDINMPGLNGYQTCERIRSEIPQPAIIFHSASDASEAVHRAYDAGADAFLTYPVDDEQLKAVL---------
+-------------------------------TSVASDIGEARSRLDNVPVDCVISALSPPDGSAIDLLRSIREDRPHLPVVIYARSGDEECASAAIGAGATDYLPADTSPAELRDRAARA------
+---TSTVVIADPKPLSLLATAGVLHHEGMR-CICARSTDAVLKAFEKFAIDLLIWDVADDPMSVLTIVQQIRQPFQNLPVVLLADSKWAGLEKKTSEIAPTHCLFKPIDPKSLITIAQHLL-----
+-------------------------------TSTVMSADPAIDNVQDFRPEMVLVDIRLGARTAFERLSIVREWFPDLPMVVIGNESGAHLILTAMRAGAQDFLDRDAADEDVRNVVARHIA----
+---TSTVLVVDDDDALAEMIGIVLAQEGYN-AVFCENGSRAFETFMRHSPDLVLLDLMLPGKSGIEVCEQIRSS-SNVPIIMLTAKSDTEDVVKGLEAGADDYIAKPFKHLELMARIRARLR----
+-------------------------------TSTVEDGEAALEVLTHKDIQFVLSDLMMPGLSGIDLCRLLKSAERYIFFVLLSSRNDQGSIVKGIDAGADDFVDKKTSVEELQARIRAGFR----
+--TSTTILLIEDEDPVRIFATKALTKKGFK-VIDISCGDQALDIINKYPIDIVISDVVMPKISGPEIVEQILKAKPDIQIIFISGYAEEFNKHSNIDATKINFLSKPFTLKQLTEKVLEIS-----
+---TSTILVVDDSAALRRTLALTLQKAGYR-VMQAKDGREALQQLQQNNVQLVVCDVEMPNMNGFEFLGQRRRELMNIPVAMLTSRSSEKHRQLATHLGASAYFTKPYIEQQFLTAVDNIVKS---
+---TSTILIADDDPGARLVLQRLLTREGHR-VLMAQNGAEALRQSIEYTPDLLLLDVLMPEIDGFEVCRQLRNRLREIPILLITSLGDQQSRVEGLSAGANGFITKPFDMAELLAHVRTITR----
+--TSTHILVVDDHKDIRDLLAKFLVKHGMR-VTVAADAAEARRHLKAGAFDLLVLDIMMPGEDGISLCRDIRDS-NSAPIIFLTAVAEDTDRIIGLELGADDYVTKPFNPRELLARIRAVIRRA--
+---TSSILIVDDEPNIAYLLRECLLAQGFN-VKEAHNPTDALAVVTKEPPDAMILDVMLPGMDGYTLLRRVREMGTECPVLFLTARDSLEDKLTGLTIGGDDYVTKPFSLEEVVARLRVILRRAG-
+--TSRRILLVEDHEDTRETLSRLLVRRGHQ-VSPAGTIRAARALAASGEFDVMISDLGLPDGEGTELLTVFANTGRKPVSIAMTGFGMEEDIRRTLAAGFVAHLTKPINIADLDRLLTS-------
+--TSPKVLVVEDEEHIRHLLKRILETEGWQ-VAEAANGMQGLEQLQTLQPDLVLLDLLMPIMDGFSFVQEMRKEWKDIPVVICTAKDLTDEDYQQLRGNVTQILHKTSN-----------------
+--TSPHILAVDDEVMLHDVFERLFPREGIE-VTACSSGTEAIELLEDAAFDLVLATHQMPGPDGMELLDHIQEHHPTVRVILLSDQDNAQNAVRAMQKGAADYIPKPFSTDELVDRVKGLLEE---
+---TSNVWVVDDDDSIRWVLERALTQAGIK-CRCFEEADSLLAEIKYEQPDAIISDIRMPGTDGLAMLDELHASLPELPIIITTAHSDLESAVASYQQGAFEYLPKPFDIDDVIAITERAISH---
+---TSMVWVVDDDPELRKMVGTYLIDQGYD-VRCLCDVKQLEARLECQRPDLLVLDVMLPGDDGLTALRRLRDAGDDLPVVMLTARGDAVDRIIGLEQGADDYLGKPFLPRELTARIDAVLRRR--
+--TSMTALIADDEPLLRHHLNRMLADVELEVVALVGDGQQALTSIEQLQPDIVFLDIRMPELDGIAVAKQLNRGEYRPTIVFVTAYD--EYAVKAFEQQAIDYLMKPLSEARLIDTCQRIKARQ--
+--TSMRILLVDDVQLDRMQLAIRLKQQGHI-VKAVGSGMEALNTYESFDPELVLLDIAMPNMNGFEVSLHIRETFPDIPIIFLSSHEEPEMIAKAIEAGGDDYLIKPVDKLVLNSKLMAMQ-----
+--TSMRILLVDDVQLDRMQLAIRLKQQGHI-VKAVGNGIEALNTYESFDPELVLLDIAMPDMNGFEVSLHIRETFPDIPIIFLSSHEEPEMIAKAIEAGGDDYLIKPVDKLVLNSKLMAMQ-----
+--TSMRILLVDDVQLDRMQLAIRLKQLGHI-VKAVGSGLEALNTYESFDPELVLLDISMPDMNGFEVSLHIRETFPDIPIIFLSSHEEPEMIAKAIEAGGDDYLIKPVDKLVLNSKLIA-------
+--TSMRILLVDDVQLDRMQLAIRLKQLGHI-VKAVGSGLEALNTYESFDPELVLLDISMPDMNGFEVSLHIRETFPDIPIIFLSSHEEPEMIAKAIDAGGDDYLIKPVDKLVLNSKLIA-------
+--TSMRILLVDDVQLDRMQLAIRLKQLGHI-VKAVGSGIEALNTYESFDPELVLLDISMPEMNGFEVSLHVRETFPDIPIIFLSSHEEPEMIAKAIDAGGDDYLIKPVDKLVLNSKLIA-------
+--TSMIVSIVDDDEHVRLATCNLLRSLGCD-VRAYSSAEAFLDSGRLGDVGCVISDVQMPGMGGIEMQRKLNEMNAALPIIFFSAFDSNATRTEALDNGALCFLDKPLNGDAVLACLEG-------
+--TSLSLLLVEDVEINRFLAERLLENAGHH-VVSAVNGIEAVEAVERENFDAVVMDIQMPELDGVEATKRIRQMKRNVPIVALTANVATEDIARYRAAGMDDCCAKPMQMEVLSPILLAI------
+--TSLRVAVFNDSATMRAAIRAALDEPDIAIVAERGDANDAAEVVARSDANAVIMDVVMPGVDGYEATRDIMRN-HPTPIVMVSSVVDAKDASAALEAGALH------------------------
+--TSLRALLVENDQVDAELLVRALTHGGFH-VTSVDTAEQMRAELARADWDVIVSDDALPTFDGMTALKLLRSTGKTIPFILMSGTVSDETAIEAVRAGARDYIRKD-QPARLVAAVRREL-----
+----TSLLVVEDESIVAMDIKHRAEGLGYRVVGMAASGEEAIKLAREEKPDLILMDIVLKEMDGIEAAEVIREE-MNIPVVYLTAYSDEKTLSRAKLTGPFGYIIKPFEDRELHSAIEVALYKH--
+----TSLLVVEDESIVAMDIKHRAEGLGYRVVGIAASGEDAIKLAREEKPDLVLMDIVLKEMDGIEAAEVIREE-MDIPVVYLTAYSDEKTLSRAKLTGPFGYIIKPFEDRELHSAIEVALYKHK-
+----TSLLLVDDDEPFLRRLAKAMEKRGFS-VETADSVAAGKAIATARPPAYAVVDLRLGDGTGLDVVETLRERRPESRIVVLTGYGAIATAVAAVKIGATDYLSKPADAADVMNAL---------
+----TSLLLVDDDEPFLRRLAKAMEKRGFS-VETADSVAAGKAIATARPPAYAVVDLRLEDGSGLDVVETLRNRRPESRIVVLTGYGAIATAVAAVKIGATDYLSKPADAADVMNAL---------
+--TSLLILVVDDEPNIRKTLTISLEAEGHR-VAAVSNSRDALMEARRRHFDLALIDLRLGAESGMELITALHASCPWMKSAVITAYASIDSAVEAMRRGAFDYLPKPFTHDQVALLVRKVVE----
+----TSLLIIEDSSDDRYLYRRLLAKYQFSSIEEVESAEEALEILQHHRPICCLLDYQLPGMDGLTFLRKLKKIDDMIPVVVLTGQGDESIAVQLMRNGAHDYLVKDLTAESLHRAIGNAVRTC--
+--TSLKVLVIEDDTEMASFIEKVLLDAGHK-VERASDGASGLAMARASEYDALIVDRMLPEKDGLTLLQEFRAAGGTTPALFLSALGDVQNKVQGLRAGAEDYLGKPFAPAELAARVEALGRRQ--
+-----TSLIIEDSLIDASLITSALEARGYGDLKVFERAEDALDYIRSDKPDFCLVDSRLPGMSGSDFIKLVKKKMDGVPCISLSTSNLKDEIRIALEAGADGYFVKPSDLEEYERVIARIIEA---
+-----TSLIIDDELFAREELADLLSSSDIEIIGQCSNAIEALQMITKLKPQLIFLDIQMPRITGIELIGMLDPD-IMPRIVFVTAYD--EFAIKAFDNYAFDYLLKPIDEKRLQQTLNRVRK----
+--TSLHVLVVEDNAVNQRLLRRQLEKAGFL-VDTANHGLQALQLLEEGAPSVVLMDLEMPVMDGLEATSRIRALPPKMPIFAITGNARQGQVDAALAVGMDEVFIKPYRLADVVARIDR-------
+--TSLHILIVEDNRTQAEYLRHLLEKRGHQ-VTVSQNGFEALERIEEKRPDIILTDVMMPDMDGYTLCKTVKQKFHDIPVILVTHLYSPVDVIKGLEAGADNFIIKPYDPEYIFSRITGIMQA---
+------TSLCDDGALQRAYIKLILQDYKFN-LYEFSSGEELLEKFNQNPFDLFFLDHRMKTITGLEAASHIRQRNQGCHIVFITASEEQG---DFKAVSPLRVLTKPAQPAAVWDILDKVAAE---
+---TSKVLLVDDEENILRAIGRLLLEDDLE-VLTATSGTEGLEVLKQHPVAVILSDQRMPGMLGADFLHQARGIAPDAVRMVLTGYADMAATMDAINKGASRYITKPWDERMLRLAIMEGVEQ---
+---TSKIFVVEDDDWYAKILMYTLSNPDYE-VIRFKSAKEVLASLH-LKPSIITLDYSLPDTKGPKLLKQLKERLPDVPVVVVSGQEDITTAVSLLKEGAYDYIVKDENTKELWKVIHHI------
+----TSIVYIEDNDTNIELMQSILSPYKNVKLLVAKTGENGIGLIRSISPDMILIDIDLPDMNGFEVCTQLQLELKHIPRVALSASAMQSDIDQAFLVGFSEYVTKPIHISTFLNVLKRLT-----
+----TSIVLVNAHALFREGLRHHLASTEFHVIGEASNGQQAIQVVDLLDPDMVVMEVDLPGVNGLEVARAIKRSHPHIRIVLLSSTMDGQEVVKAIRAGIAACVPRNIAPEKLMQTLHQVR-----
+----TSIVLVHAHALFREGLRHHISEPEFRIAGEASNGQQAIQLVDYTDPDLVLMEVDLPGVNGLEVSRAIKRTHPHVSILLFSSEMDGQQVVKAIRAGVAAYLPRNIEWPRLLTVLHEVR-----
+--TSISILVIDDDIQICELLTDTFEEYGYR-VVAVSSGQEALTLLQTNRFDLILLDLILPDINGLVLLQQLKNL-LNKPIIMLSGLNSESDVVVGLEMGADDYITKPFYPRIVVARAKAAIRRT--
+--TSIRVLLVDADSNSLLPMKNLMIQYSYQ-VTKYEDGEEAMAFLMKQEIDLVIWDFHMPDINGLDALNTIGKE-MDLPVVIMSHDHKKETVMESIKYGACDFLVKPVSKEVIAVLWRHVYRKR--
+--TSIRVLIADDQSMVRQGFTVLLNESGIEVVGQAVDGEDAVAQVAELAPDVVLMDIRMPGLGGIEATRRLTEDGATVKVLVLTTFDLDEYVYEALRAGASGFLLKDASAEELAHAVRVVA-----
+--TSIRILYVDDNNEHRDLVADALVQFRFD-VILERGASDAIDRLAAEAIHCLISEYELPDQTGLELLATVREEFPQLPFILFTGVGSEALASEAISMGVTEYLPKRYEETQHERLGNRILD----
+----TSIQVIESNPNLRSLLSWNLQQAGYH-VQQCTDMVSARDNFQAQQPNLVVLEAEFSGGQGIQLCHWLRNQ-SYPLILMLSARITEADVVTGLGAGADDYLKKPFGMKEFLARVESLTRRS--
+----TSILVVEDNMINRAILKEQLEACGAS-ITEAENGAEALDLIKVNHFDIVLSDIAMPILDGVGLIKAVRQFEPQLIMVAISGNTLHNEATAYYDAGYNYVMSKPYNTEKLYDIILKVRKRQ--
+----TSILVVEDEPAIQELISVNLSFAGHK-VLRAFDAEQAQILIRAELPDLILVDWMLPGSSGINLARKLRSRTRHIPVIMLTAKGSEQDKVDGLEAGADDYITKPFSPKELIARIKAVLRRR--
+----TSILVVDDSVTVRKVTTRLLERNGME-VRTAKDGVDAMATLQEYKPDLVLLDIEMPRMDGFEVASQMRHALKEIPIIMITSRTGEKHKERAMAIGVTDYMGKPFQEDRLLEAIAEYT-----
+----TSILVVDDDDAHRGMLRMMLQAWGYS-VDEAADGDLAVEAVRAKPYDVVLTDVRMGRMDGIHALRGILDYNPALPVVLMTAYSSVETAVDALRLGAYDYLTKPLDFDALRETLQRAVDHS--
+----TSILLVDDVEDNRLLIQRMLAKRGAN-LTLATNGQEGLTKALEKEFDIILMDIQMPVMDGYTATRKLRQAGYSKPIIALTAHAMKDDRERCLEAGCTDYLTKPVQVESLIQTILNY------
+----TSILLVDDTFVLRERLSTAMEQRGFR-VETAGNYDEAIEVFRKRPTELAVLDLRMPGKSGLELLRKLLDIAPDTRIIILSGFGSIPASIDAVRAGAVNFLSKPADADDILSAF---------
+----TSILLVDDDPIEYTIWKRKLESFELR-LEHVGDIDAAINRITEGGVDLIFLDNRLPAQDFRDTAPRLRKAGYTGPIGIISSDISGAYFREFREFGVDFRVGKDIDANMIAFIIAEYTR----
+----TSILLIDDHALFRSGMRLVLLMANVE-VLEAASLEQAVRTVTS-PPALVLLDIQLQGVNGLEGLGLFKQRWPGVPLVMLSSAAEPETIRLALSRGAAAFVSKADTAEKIIKVIEQVLS----
+----TSILIVEDEIRLAEILEDYLRREGYK-TERAKDGGRALELWRVAQPDLILLDLMLPVLDGLEVARRIRAE-SDVPIIMLTARDDEVDKLVGLGLGADDYVVKPYSPREVVARVKAVLRRV--
+----TSILIVDDEEDILELLKFNLEREGFK-IFCADSGEKALEAVKNFSPDLVLLDLMLPGIDGLEVARVLKSNTSTIPIIMLTAKGDESDVVRGLELGADDYVTKPFSPRVIIARVRAVMRRNA-
+----TSILIVDDDPDNFDVIETLLSDQNYQ-LHYTSNGTRAIASLDILQPNLILLDVMMPDMDGQQVCRAIKDKWQTLPIIMVTALDSKEDLARCLQTGADDFISKPINRVELVARVNSMLR----
+----TSILIVDDDPDNFDVIETLLSDQNYQ-LHYTSNGTRAIASLDILQPNLILLDVMMPDMDGQQVCRAIKDKWQTLPIIMVTALDSKEDLARCLQTGADDFIS---------------------
+----TSILIIEDEPLIAMDIEQLVTDIGHEVTGIARTHTEAVAEIAKRKPGMILADIQLAGSSGIDAVNEILDR-INVPVIFITAYP--ERLLTGERPEPAFLITKPFRPETVKAVISQAL-----
+----TSILIIEDDKMSQLILSRFLSGLGSR-IIVAGDGMEGLLLAKASRPDIIILDSHIPGLSGKDTLAQIRAMLQHIPVIIASGDAFKENREELLLAGADDYLVKPIEFKALQATLSKYLRAN--
+----TSILIIDDSNQVRAQIVKTLQKVSFDDYLEAADGIEAFKLVLNSPVDLILCDLEMPRMDGFKFISMLQTELKDIPVIMLTGREDRDLKIKGLEEGACDYVTKPFDAGELVARVKVQL-----
+----TSILIIDDSDQVRAQIVRTLREVSFDQYLEAGDGIDAFKTILNSRVDLILCDLEMPRMDGFKFVAMLQTELRDIPVIMLTGREDRDLKIKGLEQGACDYVTKPFDAGELVARVKVQL-----
+----TSILIADDDREIVDLVKLYLQNEGYT-IYQAYDGAEVWRLVQEKQPTLVILDIMMPEMDGLEVCRLMRKSGILTPILMLSAKAEDNDKIMGLLTGADDYMVKPFNPLELSVRVKAILRRMQ-
+----TSILIADDDKEIVDLVKLYLQNEGYT-IYQAYDGAEVWRLVQEKQPTLVILDIMMPKMNGLEVCRLMRNNGILTPILMLSAKAEDNDKIMGLLTGADDYMVKPFNPLELSVRVKAILRRMQ-
+----TSILIADDDKEIVDLVKLYLQNEGYT-IYQAYDGAEVWRLVQEKQPTLVILDIMMPEMNGLEVCRLMRNNGILTPILMLSAKAEDNDKIMGLLTGADDYMVKPFNPLELSVRVKAILRRMQ-
+----TSILIADDDKEIVDLVKLYLQNEGYT-IYQAYDGAEVWRLVQEKQPTLVILDIMMPEMNGLEVCRLMRKNGILTPILMLSAKAEDNDKIMGLLTGADDYMVKPFNPLELSVRVKAILRRMQ-
+----TSILIADDDKEIVDLVKLYLQNEGYT-IYQAYDGAEVWRLVQEKQPTLVILDIMMPEMNGLEVCRLMRDNGILTPILMLSAKAEDNDKIMGLLTGADDYMVKPFNPLELSVRVKAILRRMQ-
+----TSILIADDDKEIVDLVKLYLQNEGYT-IYLAYDGAEVWRLVQEKQPTLVILDIMMPEMNGLEVCRLMRSEGILTPILMLSAKAEDNDKIMGLLTGADDYMVKPFNPLELSVRVKAILRRMQ-
+----TSILIADDDKEIVDLVKLYLQNEGYT-IYLAYDGAEVWRLVQEKQPTLVILDIMMPEMDGLEVCRLMRSEGILTPILMLSAKAEDNDKIMGLLTGADDYMVKPFNPLELSVRVKAILRRMQ-
+----TSILFADDSAIARMLVEESLKTMGVA-YSAVKNGKEAWERLGKDKVALVLTDLEMPEMDGFTLTRSIKNRFAGIPVIVYSSLTGSASEGHASGVGADAYVAK-FEPNELANAISTTLTR---
+--TSIKALLVEDIEVCRLVLSTILLAMNCE-VTLAVNGKEAVELFLEKKFDIVLLDKDMPIMTGPEAVVKIRAMEGDVKIVGVSADD--HAMEAFMNAGADAFVPKPMRREVLIPIIQEIINKK--
+---TSHVLLVEDDVEVGDLVAAMIDELGHM-VSRAANADEALAIARADPLGLVITDVIMPGKSGVDLAITLASERPELPILLSSGYTGQE-LMRAH-DTPWPLLRKPYALDALAQAMADAWDRHG-
+---TSHVLLVDDNAAEIYPLVEALRKFPFR-LTVAGDGIQAYAQAVSTVPDIILMDVRMPRRDGITTTRLLKASTQHIPILFLAAAATLEDRLEGLRSGAVDYILKPFEAEEVVEKVRIH------
+--TSHKILVVDDDPRLRDLLRRYLGEQGFT-VLVAENATAMNKLWLRERFDLLVLDLMMPGEDGLSICRRLRGANDQTPIIMLTAKGEDVDRIVGLEMGADDYLPKPFNPRELIARIHAVLRRKG-
+---TSHILVVDDDHEIRTLLAEYLDANGLR-AFVASNGSDMRRVLEQTRIDLIVLDLTLPGEDGLTLCRNLRAHHGGVPVIMLTARGEPLDRIIGLEMGADDYLPKPFEPRELFARIRSVLRRT--
+--TSFRLVIADDHPLFRGALREAVSRQQAE-LFEAGGFEDLQALLERGDLDLILLDLTMPGVRGFSGLMYLRAQYPGIPVVVVSANEEAGVIRNCMEFGASGFIPKTSAVETMREAVAAVLEG---
+----TSFLVVEDNAHMRSILRSILAGFGVRQIFDAGDGADGLEFAIERYPDVILLDWSMVPVSGSDFLRILRAQLRTTPVLIVSAQCQRSTVIEAVKLGIHGFIAKPVSPTLLYQHVVNILMRQ--
+--TSFDILIVDDQVGVRRLLFEALADEGYI-VKMAGSGAEALQVLSQTLPSLVLLDIKMSGMTGIETLQEIRKHYAQLPVAMMTAYGDMEIMDQTKSLGVQHYLNKPFDLDDVRVLVRSILSRS--
+---TSEIWIAEDDRSLRWVMEKAISREGIE-VRSFENGDDLLVALQSSLPEIIISDIRMPGIDGLELLKKIHSTRPDIPVIITTAHSDLDSAVAAYQGGAFEYLPKPFDLDELVDVARR-------
+------------------------TSEGFT-VETAESGHEGLRILGREKIDLVISDLRMDEMDGMQLFAEIQKLQPGMPVIILTAHGSIPDAVAATQQGVFSFLTKPVDKDALYKAIDDALAHA--
+-------------------------------------------------TSCLIADMHSSAMSGLELFDHLVASRGAIPTVLLTGHSEHD----VRRGPGLQFMSKPFEGSELLACVRSQIAN---
+--TSATLLLIDDDEVVRASIAAYLEDSGFN-ILLASNGLQGLEVFERERPDLVVCDLRMPQVDGLELIRRISALEYSAPIIVVSGAGVMTDVVEALRLGAADYLIKPLDLAVLEHSVRRALDRV--
+--TSATLLIIDDDEVVRASLAAYLEDSGFS-VLQASNGQQGLQVFERDQPDLVICDLRMPQMGGLELIRQVTERAPQTPVIVVSGAGVMNDAVEALRLGAADYLIKPLDLAVLEHSVRRALDRA--
+--TSATLLIIDDDEVVRASLAAYLEDSGFS-VLQASNGQQGLQVFERDQPDLVICDLRMPQMGGLELIRQVTELAPQTPVIVVSGAGVMNDAVEALRLGAADYLIKPLDLAVLEHSVRRALDRA--
+--TSATLLIIDDDEVVRASLAAYLEDSGFS-VLQAANGQQGLQVFERDNPDLVICDLRMPQMGGLELIRQVTELSPQTPVIVVSGAGVMNDAVEALRLGAADYLIKPLDLAVLEHSVRRALDRA--
+--TSATLLIIDDDDVVRASLAAYLEDSGFS-VLQASNGQQGLQVFEEHQPDLVICDLRMPQMGGLELIRQVSERAPQLPVIVVSGAGVMSDAVEALRLGAADYLIKPLDLAVLEHSVRRALDRS--
+--TSATLLIIDDDDVVRASLAAYLEDSGFS-VLQAGNGQQGLQVFEEHQPDLVICDLRMPQMGGLELIRQVSERAPQVPVIVVSGAGVMSDAVEALRLGAADYLIKPLDLAVLEHSVRRALDRS--
+--TSATLLIIDDDDVVRASLAAYLEDSGFS-VLQAGNGQQGLQVFEEHQPDLVICDLRMPQMGGLELIRQVSERAPQLPVIVVSGAGVMSDAVEALRLGAADYLIKPLDLAVLEHSVRRALDRS--
+--TSATLLIIDDDDVVRASLAAYLEDSGFS-VLQAANGQQGLQVFEEHQPDLVICDLRMPQMGGLELIRRVSERAPQLPVIVVSGAGVMSDAVEALRLGAADYLIKPLDLAVLEHSVRRALDRS--
+--TSATLLIIDDDDVVRASLAAYLEDSGFK-VLQANNGLQGLEVFQQESPDLMICDLRMPQVDGLELIRRINALGVEVPVIVVSGAGVMNDAVEALRLGAADYLIKPLDLAVLEHSVRRALDRS--
+--TSATLLIIDDDDVVRASLAAYLEDSGFK-VLQANNGLQGLEVFQQEGPDLMICDLRMPQVDGLELIRRINALGVEVPVIVVSGAGVMNDAVEALRLGAADYLIKPLDLAVLEHSVRRALDRS--
+--TSARLLLVDDDPSLLKLLGMRLRSEGFT-VDTASSGPEALRVLNRENVDLAISDLRMDEMDGMALFVEIQKLKPGMPVIILTAHGSIPDAVAATRQGVFSFLTKPVDRDALYKAIDEALA----
+--TSARILLADDNADMRDYLKHLLQP-DYE-VEAATNGLAALAAARRQIPDLVLSDIMMPGIDGLQLLRELRSSTREVPIILLSARAGEESRVEGLEMGADDYLIKPFSARELLARVRTNL-----
+--TSAKLLIIDDDDVVRASLAAYLEDSGFS-VLQASNGLQGIQTFEQETPDLVVCDLRMPQMGGLELIRQVTAVAPQTPVIVVSGAGVMSDAVEALRLGAADYLIKPLDLAVLEHSVRRALDRA--
+--TSAKLLIIDDDDVVRASLAAYLEDSGFS-VLQASNGLQGIQMFEQENPDLVVCDLRMPQMGGLELIRQVTAIAPQTPVIVVSGAGVMSDAVEALRLGAADYLIKPLDLAVLEHSVRRALDRA--
+--TSAKLLIIDDDDVVRASLAAYLEDSGFS-VLQASNGLQGIQIFEQENPDLVVCDLRMPQMGGLELIRQVTAIAPQTPVIVVSGAGVMSDAVEALRLGAADYLIKPLDLAVLEHSVRRALDRS--
+--TSAKLLIIDDDDVVRASLAAYLEDSGFS-VLQASNGLQGIQIFEQENPDLVVCDLRMPQMGGLELIRQVTAIAPQTPVIVVSGAGVMSDAVEALRLGAADYLIKPLDLAVLEHSVRRALDRA--
+----------------TRYVERELQQCGYR-TLVVPDTIDAFSLAVQSKPDLVIISALMPHLDGIDLAIALVSSTRNIPIAVITSLDSHNES----------------------------------
+--TRYTVMLLDNHEMVRQGIELGLNEADIEVIGSFGSGRELLETLAVRLADVVVMDFALGDIDGLSLIQALNRRFKQCRPIVVCSHYTPAIVSLALKAGSWGVLGKNEKLSELITAIRTAAQ----
+--TRYSVLVVEDNPTNQMVIQLILARQGHE-VFIASNGEEAIGFVERDPIDIILMDVSMPVMDGITTTKYMRDANIKTPIVALTAHTSVEDKFSCLDVGMNDFITKPVRTKEIIEAIDRLM-----
+--TRYRVLVVDDSIFVSKQIGQILTSEGYEVAGTAADGLEGVEKYKAPNVDLVTMDITMPKMDGITALEQIMDFDKNAKVVMISALGKEELVKKALLLGAKNYIVKPLDRKKVLERISNVLAK---
+--TRYKIAIIEPMEITRKNYVEWLSE-DYD-VVCISNLTSPLKELKKISPDIILMDINLSDKDYFYLLEEIKNSLRTALIIIITKRYNEDDVVNGLEKGACDYVKKPVGQNELKARIRNAVR----
+----TRVYILDSHALVRTGLRELLEEAHFTVVGESGSASEASRRIPELCPDLVVIGAHLPDGTGIEVCREILADNPGVRCLLLSSYDDDHALSSAVLAGAAGYVLRQLPGTALVEGIRRVAT----
+----TRVVVADDQPVVLQGFAAILGSVDLDVVGTAPDGRALVDLVARTAPDVAVVDVRMPVLDGIAATVRVVAEHPGTRVLILTTFDLDEYVYDALRAGASGFLLKDVTAERLVDAVRLV------
+----TRVVVADDQPVVLEGFAAILGAADLEVVGTAPDGVELVDLVTRTRPDVAVVDVRMPQLDGIAATRRIRDAHPATHVLMLTTFDLEEYVADALQAGASGFLLKDVPAARLVEGVRL-------
+----TRVVVADDQLLVRTGLTMILNQPGIEVVGEATDGHEAVDVARRLRPDVCLFDIRMPGIDGVEATRRLAGVEDPLAIVIITTFDLDEYVHGALKAGARGFLLKDAGPELLVQAIHAAA-----
+----TRVVVADDHAVVRAGLRSALASLEFEVVGEAADGPQLLAVLAQHQPDLLVVDVAMPDFEPIATIRQIHATYPAMKILVVSAYDDQSYVVGLLAAGVNGYHLKDQPLSDLQLAVQRIM-----
+----TRVVIAEDEALIRLDLKEMLEEEGYTVVGEAGDGQQAVELAREHQPDLVILDVKMPVLDGISAAEKIAEE-SIAPVLMLTAFSQRDLVERARDAGAMAYLVKPFSKSDVVPAIEMAVSRF--
+----TRVVIAEDEALIRLDLKEMLEEEGYTVVGEAGDGQQAVELAREHKPDLVILDVKMPVLDGISAAEKIAEE-SIAPVLMLTAFSQRDLVERARDAGAMAYLVKPFSKSDVVPAIEMAVSRF--
+----TRVVIAEDEALIRLDLKEMLEEEGYTVVGEAGDGEQAVELAREHRPDLVILDVKMPKLDGISAAEKIAEE-SIAPVLMLTAFSQRDLVERARDAGAMAYLVKPFSKSDVVPAIEMAVSRF--
+----TRVVIAEDEALIRLDLKEMLEEEGYTVVGEAGDGAKAVELAREHRPDLVILDVKMPVLDGISAAEKIAGE-SIAPVLMLTAFSQRELVERARDAGAMAYLVKPFSKSDVVPAIEMAVSRF--
+----TRVVIAEDEALIRLDLKEMLEEEGYSVVGEAGDGQTAVELAREHRPDLVILDVKMPVLDGISAAEKIAGE-SIAPVLMLTAFSQRDLVERARDAGAMAYLVKPFSKSDVVPAIEMAVSRF--
+----TRVVIAEDEALIRLDLKEMLEEEGYSVVGEAGDGQTAVELAREHRPDLVILDVKMPVLDGISAAEKIAEE-SIAPVLMLTAFSQRDLVERARDAGAMAYLVKPFSKSDVVPAIEMAVSRF--
+----TRVVIAEDEALIRLDLKEMLEEEGYSVVGEAGDGQRAVELAREHRPDLVILDVKMPVLDGISAAEKIAEE-SIAPVLMLTAFSQRDLVERARDAGAMAYLVKPFSKSDVVPAIEMAVSRF--
+----TRVVIAEDEALIRLDLKEMLEEEGYSVVGEAGDGQQAVELAREHRPDLVILDVKMPVLDGISAAEKITEE-SIAPVLMLTAFSQRDLVERARDAGAMAYLVKPFSKSDVVPAIEMAVSRF--
+----TRVVIAEDEALIRLDLKEMLEEEGYSVVGEAGDGQQAVELAREHKPDLVILDVKMPVLDGISAAEKIAEE-SIAPVLMLTAFSQRDLVERARDAGAMAYLVKPFSKSDVVPAIEMAVSRF--
+----TRVVIAEDEALIRLDLKEMLEEEGYSVVGEAGDGQQAVDLAREHKPDLVILDVKMPVLDGISAAEKIAEE-SIAPVLMLTAFSQRDLVERARDAGAMAYLVKPFSKSDVVPAIEMAVSRF--
+----TRVVIAEDEALIRLDLKEMLEEEGYSVVGEAGDGETAVALAQEHRPDLVILDVKMPVLDGISAAERIAAD-RIAPVLMLTAFSQRELVERARDAGAMAYLVKPFSKSDVVPAIEMAVSRF--
+----TRVVIAEDEALIRLDLKEMLEEEGYSVVGEAGDGERAVELAREHRPDLVILDVKMPKLDGISAAEKIAEE-SIAPVLMLTAFSQRDLVERARDAGAMAYLVKPFSKSDVVPAIEMAVSRF--
+----TRVVIAEDEALIRLDLKEMLEEEGYSVVGEAGDGEQAIELAREHRPDLVILDVKMPKMDGISAAEKIAEE-RIAPVLMLTAFSQRDLVERARDAGAMAYLVKPFSKSDVVPAIEMAVSRF--
+----TRVVIAEDEALIRLDLKEMLEEEGYSVVGEAGDGEQAIELAREHRPDLVILDVKMPKLDGISAAEKIAEE-RIAPVLMLTAFSQRDLVERARDAGAMAYLVKPFSKSDVVPAIEMAVSRF--
+----TRVVIAEDEALIRLDLKEMLEEEGYSVVGEAGDGEQAIELAREHKPDLVILDVKMPKLDGISAAEKIAEE-RIAPVLMLTAFSQRDLVERARDAGAMAYLVKPFSKSDVVPAIEMAVSRF--
+----TRVVIAEDEALIRLDLKEMLEEEGYSVVGEAGDGEEAVELAREHRPDLVILDVKMPKMDGISAAEKIAEE-SIAPVLMLTAFSQRDLVERARDAGAMAYLVKPFSKSDVVPAIEMAVSRF--
+----TRVVIAEDEALIRLDLKEMLEEEGYSVVGEAGDGAKAVELAREHRPDLVILDVKMPVLDGISAAEKIAEE-SIAPVLMLTAFSQRDLVERARDAGAMAYLVKPFSKSDVVPAIEMAVSRF--
+----TRVVIAEDEALIRLDLKEMLEEEGYAVVGEAGDGQRAVELAREHRPDLVILDVKMPVLDGISAAEQIAAE-SIAPVLMLTAFSQRDLVERARDAGAMAYLVKPFSKSDVVPAIEMAVSRF--
+----TRVTIVDDHPLVAEGIEAILDSYDISVVATLSDGQSMIDRLDELNPDVILMDLNMPGLGGLSATEMILERAPDTRILVLSMHDTPEYISTALTHGARGYVLKDVPTDEIKHAIDAVMR----
+----TRVSVVDDDPLARKIICELLNQNELSVVSSYDDGQALIDDLDRDQTDVYLCDIAMPQLDGIDTTKAIRERGDTTPIMLLTSYDVEERFIQGMQAGANGYLIKTSDISQIRAAILSIA-----
+--TRVRVILAEDDVLLREGVASLLTRSGFDVREQVGDATTLLELVRTQTPDLVVVDIRMPTTEGLDAARVIRDEFPEVGILVLSAHADVEHAMELLASGGIGYLLKSTDVDDFIDTLQRIA-----
+--TRVRILLVEDDLRVARVNRDLLERDDVHVVGSAATCAQGDALAQALQPDLILLDVHLPDGSGLGLLRHWRSAGRTTDVALITAADDESSVRLALAHGAFDYLIKPFTGQRLAELVARHR-----
+----TRVMVVDGSKLVRKLIADVLTREGVE-VIGCDSIEDAQQALAQGPVDLVTTSLTLRDGDGLALARMVRDAQAYVPVIVVSGDAQQHLEQRRFTEYVTDYFDKALGHEALATFIRGYVQ----
+----TRVMVVDGSKLVRKLIADVLRRDGVE-VIGCDSIEEAQQALAQGPVDLVTTSLTLRDGDGLALARMIREAQAYVPVIVVSGDAQQHLEQRRFTEYVTDYFDKALGHEALATFIRGYVQ----
+----TRVMVVDGSKLVRKLIADVLQRDGVE-VIGCDSIEDAQQALAQGPVDLVTTSLTLRDGDGLALARMVREAQAYVPVIVVSGDAQQHLEQRRFTEYVTDYFDKALGHEALATFIRGYVQ----
+----TRVMVVDDHPMWRDAVARDLEAAGFAVVATAGDGPQAVRRASAALPDVLVLDLNLPGLPGVEVCKRLVRERSGPHVLVLSASGEHQDVLEAVKSGATGYLLKSASTEELIDAVRRT------
+----TRVMVVDDDLSVCATLVAFLEDCGYE-VYSFNSGESAYEWIRTNRVDVAVVDLRLPAMSGDRLILNMRELLPDLPCVIYTGSPDFDPGSQYVELENVPVFRKPVDLTVLLDEIEALSQEV--
+----TRVMVIEDDIAIAELHHRYLEQMGFDVVGIATTQSEALMQLDILKPDLVLLDVYLPDGCGLDILNHVRGSNQGCDVILITAARDVDTLQQAMRGGVVDYLLKPVMFPRLEAALKKYQSQ---
+----TRVMIVDDHPMWREGVARDLGSRGYDVCATASDVAGAIGIALATRPDVVVMDLQLGDGSGVDATREITAALPDTRVLVLSASAEQSDVLAAVKNGASGYLVKSASLDEFDDAVRRTAE----
+----TRVMIIEDEPVIALDLRAIVENAGHSVTGVARTRDQAVALAQKSPPGLVLADIQLADSSGIDAVKDILDE-MNVPVIFITAYP--ERLLTGEKPEPTYLVTKPFMPETVSATISQAL-----
+----TRVMIIEDDLNIAQLHQRYLEQEGYEVIGIATTKVEAEIQLDVLNPDLLLLDVYLPDGTGLELLQELRARNQSCDVILITAARDVDTLQQAMRGGVVDYLLKPVVFPRLEAALKKYVVQ---
+----TRVMIIEDDLKIAELHRRYLEQIGFEVVGMATSKAEAEIQLEILEPELVMLDVYLPDGTGIEILAWLRSLNQECDVILITAARDVETLQQAMRGGVIDYLLKPVMFPRLEAALKKYQKRT--
+----TRVMIIEDDLAIAQLHQRYLEQVGYEVIGIATTKLEAKLQLEVLSPDLLLLDVYLPDGTGIEILHELRTEHLSCDVILITAARDVETLQQAMRGGVVDYLLKPVVFPRLEAALKKYVLQ---
+----TRVMIIEDDLAIAQLHQRYLEQIGYEVIGIATTKLEAGLQLEVLAPDLLLLDVYLPDGTGLDILHELRSNNLSCDVILITAARDVETLQQAMRGGVVDYLLKPVIFPRLEAALKKYTSQK--
+----TRVMIADDHAVVRDGLRHILERAGFEVVGEAADGTQVPRMVRECTPQVLLLDLSMPGRSGLELIRLLRGEHPALRILVLTMHAEEQYIVRAFQAGAAGYLTKESAATELVSAIGQVAR----
+----TRVLYIEDNHDNQRLVRRVLATRGYQ-IIIANDGNEGWKSAQTDRPDLILMDINLPGLNGYELTTKFKAQLASVPIVALTANTTPGDRERALAAGCDGYISKPIDPRALPDLVASY------
+----TRVLYIDDEKTLLTLTQIYLREANLD-VEIAASAEEGLVLLRNESFDAIISDYDMPDMDGIELLKCVRKENPTIPFIVFTGKGREEIVIEALNYGADFYLQKGGDPKELANAIRHLVRR---
+----TRVLYIDDDDALARLVQKKLGRLGFV-VEHASSPEQALTRLEEGGFDVLALDHYLGAGTGLEFLARLATRGAAPPAVYVTGSSEMSVAVAALKAGASDFVPKTIGD-DFIALLASALD----
+----TRVLVVEDSEEDAEAIERALTRTHPARLEFTAHGDGLAERLDEELPGMILLDLNMPGADGHKVLAALRAELAGLTVVVFTSSTAPAEVDACYAAGADSYIYKPVNFDLFRTVLKGAV-----
+----TRVLVVEDNRLNQEVLQGLLQRVGVQ-VVLAANGAQALRLLEEGRFDAVLMDCQMPVMDGFATTRKIRGHLRWLPIIAVTASSQADVQGRAVAAGMSDLLSKPLEVAAFYRTLVRWIKAT--
+----TRVLVVEDNRLNQEVLQGLLQRVGGQ-VVLAANGAQALRLLEEGRFDAVLMDCQMPVMDGFATTRKIRGHLRWLPIIAVTASSQADVQGRAVAAGMSDLLSKPLEVAAFYRTLVRWIKAT--
+----TRVLVVEDHFPDAVLLEEWLELAEVQEVVHVVTFAEATSRWPDGRFDALLLDLDIPDGFGLDLVERGLALAGAVPVVVLSGRADEAVAAGAVGLGARAYVVKPASVHELRAALE--------
+----TRVLVVEDESSYSEALSYVLRKEGFD-VAIAETGPDALLEFDRAGADIVLLDLMLPGLSGTEVCRQLRQT-SSVPIIMVSAKDTEVDKVVGLELGADDYVTKPYSPRELVARIRAVLRR---
+----TRVLVVEDEESYSDALSYVLRKEGFE-VAVAETGPDALDEYDRAGADIVLLDLMLPGLSGTEVCRALRTR-GNVPVIIVSAKDTEVDKVVGLELGADDYVTKPYSPRELLARIKAVLRR---
+----TRVLVVEDEESYSDALSYMLRKEGFE-VAVAPTGTVALETFDRTGADLVLLDLMLPGLSGTEVCRTLRQK-SNVPVIMLTAKDSEIDKVVGLELGADDYVTKPFSSRELVARIRAVLRRRG-
+----TRVLVVEDEESYSDALSYLLRKEGFE-VAVAPTGTSALEIFDRTGADLVLLDLMLPGLSGTEVCRTLRQK-SNVPVIMLTAKDSEIDKVVGLELGADDYVTKPFSSRELVARIRAVLRRR--
+----TRVLVVEDEESYSDALAYMLRKEGYE-VAIAANGNDALTEFDRNGADIVLLDLMLPGLPGTEVCRQIRQT-SSVPVIMVSAKDDEVDKVVGLELGADDYVTKPYSPRELVARIRAVLRR---
+----TRVLVVEDEESFSDALSYNLRKEGFE-VAVASTGPDALEIFDRNGADLVLLDLMLPGLPGTEVCRELRAR-SNVPVIMLTAKDSEVDKVVGLELGADDYVTKPFSTRELIARMRAVLRRRG-
+----TRVLVVEDEESFSDALSYMLRKEGFE-VAVATTGPDGLDEFERNGADLVLLDLMLPGLPGTEVCRQLRGR-SNVPVIMVTAKDSEIDKVVGLEIGADDYVTKPFSSRELVARIRAVLRRRG-
+----TRVLVVEDEESFSDALSYMLRKEGFE-VAVAATGPEGLDEFERNGADLVLLDLMLPGLPGTEVCRQLRGR-SNVPVIMVTAKDSEIDKVVGLEIGADDYVTKPFSSRELVARIRAVLRRRG-
+----TRVLVVEDEESFSDALSYMLRKEGFE-VAVAATGPEALDTFDRNGADLVLLDLMLPGLPGTEVCRSLRQR-SNVPVIMLTAKDSEIDKVVGLELGADDYVTKPFSSRELVARIRAVLRRQG-
+----TRVLVVEDEESFSDALSYMLRKEGFE-VAVAATGPDGLDEFERNGADLVLLDLMLPGLPGTEVCRQLRGR-SNVPVIMVTAKDSEIDKVVGLEIGADDYVTKPFSSRELVARIRAVLRRRG-
+----TRVLVVEDEESFSDALSYMLRKEGFE-VAVAATGPDALEQFERNGADLVLLDLMLPGLPGTEVCRQLRVR-SNVPVIMVTAKDSEIDKVVGLEIGADDYVTKPYSTRELVARIRAVLRRRG-
+----TRVLVVEDEESFSDALSYMLRKEGFE-VAVAATGNEALKEYEKAGADIVLLDLMLPEKSGTEVCRELRTT-SNVPIIMVTARDSEVDKVVGLEIGADDYITKPYSPRELVARIRAVLRRN--
+----TRVLVVEDEESFSDALSYMLRKEGFE-VAVAASGPEALEVFDREGADLVLLDLMLPGLPGTEVCRSLRQR-SKVPVIMLTAKDSEIDKIVGLELGADDYVTKPFSSRELVARIRAVLRRRG-
+----TRVLVVEDEESFSDALSYMLRKEGFE-VAIATTGPEGLDEFERNGADLVLLDLMLPGLPGTEVCRQLRGR-SNVPVIMVTAKDSEIDKVVGLEIGADDYVTKPFSSRELVARIRAVLRRRG-
+----TRVLVVEDEESFSDALSYMLRKEGFE-VAIATTGPDGLDEFERNGADLVLLDLMLPGLPGTEVCRQLRGR-SNVPVIMVTAKDSEIDKVVGLEIGADDYVTKPFSSRELVARIRAVLRRRG-
+----TRVLVVEDEESFSDALSYMLRKEGFE-VAIAATGPEGLDEFERNGADLVLLDLMLPGLPGTEVCRQLRGR-SNVPVIMVTAKDSEIDKVVGLEIGADDYVTKPFSSRELVARIRAVLRRRG-
+----TRVLVVEDEESFSDALSYMLRKEGFE-VAIAATGPDGLDEFERNGADLVLLDLMLPGLPGTEVCRQLRVR-SNVPVIMVTAKDSEIDKVVGLEIGADDYVTKPFSSRELVARIRAVLRRRG-
+----TRVLVVEDEESFSDALSYMLRKEGFE-VAIAATGPDGLDEFERNGADLVLLDLMLPGLPGTEVCRQLRSR-SNVPVIMVTAKDSEIDKVVGLEIGADDYVTKPFSSRELVARIRAVLRRRG-
+----TRVLVVEDEESFSDALSYMLRKEGFE-VAIAATGPDGLDEFERNGADLVLLDLMLPGLPGTEVCRQLRGR-SNVPVIMVTAKDSEIDKVVGLEIGADDYVTKPFSSRELVARIRAVLRRRG-
+----TRVLVVEDEESFSDALSYMLRKEGFD-AVVANNGPEALAEFERGGADVVLLDLMLPGLPGTEVCRQLRSR-SSVPIIMLTAKDAEVDKVVGLELGADDYVTKPYSARELVARIRAVLRRRG-
+----TRVLVVEDEEFFSDALSYMLRKEGFE-VAIAATGPDGLDEFERNGADLVLLDLMLPGLPGTEVCRQLRSR-SNVPVIMVTAKDSEIDKVVGLEIGADDYVTKPFSSRELVARIRAVLRRRG-
+----TRVLVVEDEDSISDPLSYMLRNEGFE-VAVADTGPAALEEFDRHGADLVLLDLMLPGLPGTEVCRQIRAK-SNVPVIMLTAKDSEIDKVVGLELGADDYVTKPFSARELVARIRAVLRRQA-
+----TRVLVVEDEASYSEALSYMLRKEGFE-VAVAEDGTDALKEFDRNGADIVLLDLMLPGLSGTEVCRQIRAT-SSVPVIMVTAKDDEVDKVVGLELGADDYVTKPYSPRELVARIRAVLRR---
+----TRVLVVEDDPQLVRALVLNMRARHYG-VEAAPDGATALRLAVAGRPDVVLLDLGLPDMDGVDVIKALRG-WTRVLILVLSARQAS-------------------------------------
+----TRVLVVEDDPQLVRALVINLQARHYD-VDAAPDGTTALRLAASHQPDVVVLDLGLPDMDGVDVIKALRG-WTPVPVLVLSARRASEEKVAALDAGADDYMTKPFSMDELLARLRASVRRT--
+----TRVLVVEDDPQLVRALKINLQARKFE-VLEAGDGAMALRLAAARTPDAILLDLGLPDMDGVEVIRGVRG-WSHVPILVLSARHTSEEKIRALDAGADDYVTKPFSMDELLARLRAATRRQ--
+----TRVLVVEDDPQLVRALKINLQARKFE-VEEASDGGSALRLAASHKPDVIVLDLGLPDMDGIEVIKGVRV-WSKVPILVLSARHTSEDKIRALDAGADDYVTKPFSMDELLARLRAAARRHE-
+----TRVLVVEDDDVIRELIRLNLELEGFE-VFTAVDGQDCLDRAAHIDPHVVTMDVMMPRVDGWTAVERLRARTRDRPIIMVTARTQETDHQRGRRVGMDAYLTKPFDPDVLIDIIRSLVDR---
+----TRVLVVDNDADALAAMQQLLLSWGCD-V-IAVRGAEGIDAS-AHDAALWLFDYHLDGDTGVALFTRLAAAQGPRPTVILSADTGAETREAVRGAGL-SLLSKPFRPLALRWAINHLLASA--
+----TRVLVVDDSRTFRKALRLIFSRSDIAVVGEAESAEEALSLLGALSPDVVTLDIEMPGMGGLLLAERIRTD-FSARILVVSGQTHSRTAVEALLKGAHDILEKPADME---------------
+----TRVLVVDDSRFMRTVIGNALTEAGYE-VETATNGVEAVDTAAEFDPAVVTMDVEMPEMNGIEAVERIMAQ-NPTLILMLSAYTDEDATLDALERGAIEFLPKP-------------------
+----TRVLVVDDSGFMRTVIGNALTEAGYE-VETATNGSEAIEAVAAYDPDVVTMDVEMPKLGGIDAVERIMAT-NPTLILMLSVHTEEEATLDALERGAVDFLHKP-------------------
+----TRVLVVDDSAFVRLAVTEILREAGIEVVGTAKNGKEAVEKTLELEPDVVILDVKMPVMDGLTALKHIMEK-KPTPVLMFSSYTKEDAKEEALKLGAVDFVPKP-------------------
+----TRVLVVDDQTVVRDGLVLILGLLDIEVVGAAADGAEALRLVDEHHPDVVLMDLRMPRMDGAEATGRIKAAHPEVQIVVLTTYSDDESVFAALKAGARGYLTKDAGGEEIAAAIAAV------
+----TRVLVVDDNVANQAVARAVLEAAGVL-VGTANDGRQALARLRVEDFDLVLMDVHMPVMDGIEALRRVRGGRADVPVMALTADAMSGEAERLVGLGFDDAQPKPIQPAGLLRAIAR-------
+----TRVLVVDDHRIFAESLAAALAAEDVD-VGAAGSGPAALRSLERRPFDVVLVDADLGVLDGISLVGGLRATQPGVRTVVLAERDDPRRAALALQAGASGWVAKDCSLSRLLTVVRGVLRDE--
+----TRVLVVDDHPVVRGGLVGWLDQPDLTVVGEASDGLEALAMVASLDPDVVLMDLRMPRMDGVAAIERLAGTHPGVRVLVLTTYDTDADIVRAVAAGATGYLLKDAPLPQLADAVRAAAR----
+----TRVLVVDDHPVLRDGVRAALVAASLDIVGEAASAADAVRLAVELRPDVVLLDLQLPDFSGIEAARRIARDAPDAAVLAFTMSDDDETVFAALRAGAIGYVVKGVESRELVHAIETVAH----
+----TRVLVVDDHLLSRKGIASILSAHPFEIAGEATNGQEAVEQARRLVPDLILMDIRMPNGSGLEATRRLKEEMPYVKIIILSVSDDVQDFFEAIKYGAQGYLLKNMEPEYWLDYIMSIVQ----
+----TRVLVVDDHEVVRRGLMTLIDEETMETVGEASCGQDGIDLAVSLAPDVVLMDVQLPDVDGITAARTIIES-TSCKVVMLTALADEEVVYGGLRAGVSGFLLKVAPSHELIEAVSLA------
+----TRVLVVDDEPQLLRALRINLTARGYE-VLTAVDGKAALRAAGDGKPDAVVLDLGLPDMDGSEVIAGLRG-WTTVPIIVLSARTDSTDKVHALDAGADDYVTKPFGMDELLARLRAAVRRAN-
+----TRVLVVDDEPQIVRALVINLRARHYE-VDAAADGAAALQLAAARHPDVVVLDLGLPDMDGVEVIRGLRG-WTRVPILVLSARHSSDEKVEALDAGADDYVTKPFGMDELLARLRAAVRRA--
+----TRVLVVDDEPQIVRALVINLKARRYE-VDAAPDGATALQLAAARHPDVVVLDLGLPDMDGVEVIRGLRG-WTRVPILVLSARHTSDEKVEALDAGADDYVTKPFGMDELLARLRAAVRRA--
+----TRVLVVDDEPQIVRALVINLKARQYE-VDAAPDGATALQLAAARHPDVVLLDLGLPDMDGVEVIRGLRG-WTRVPILVLSARQTSDEKVEALDAGADDYVTKPFGMDELLARLRAAVRRA--
+----TRVLVVDDEPQIVRALVINLKARQYE-VDAAPDGATALQLAAARHPDVVLLDLGLPDMDGVEVIRGLRG-WTRVPILVLSARHTSDEKVEALDAGADDYVTKPFGMDELLARLRASVRRA--
+----TRVLVVDDEPQIVRALVINLKARKYE-VDSAHDGASALELAAARHPDVVVLDLGLPDMDGVEVIRGLRG-WTRVPIIVLSARHASDEKVEALDAGADDYVTKPFGMDELLARMRAAVRRA--
+----TRVLVVDDEPQIVRALVINLKARKYE-VDAASDGAGALELAAARHPDVVVLDLGLPDMDGVEVIKGLRG-WTRVPILVLSARHSSDEKVEALDAGADDYVTKPFGMDELLARLRAAVRRA--
+----TRVLVVDDEPQIVRALVINLKARKYE-VDAAPDGATALRLAAERHPDVVVLDLGLPDMDGVEVIKGLRG-WTRVPILVLSARQTSDEKVEALDAGADDYVTKPFGMDELLARLRAAVRRA--
+----TRVLVVDDEPQIVRALVINLKARKYE-VDAAPDGATALQLAAARHPDVVVLDLGLPDMDGVEVIKGLRG-WTRVPILVLSARHTSDEKVEALDAGADDYVTKPFGMDELLARLRAAVRRA--
+----TRVLVVDDEPQIVRALVINLKARKYE-VDAAHDGATALKLAAARQPDVVVLDLGLPDMDGVDVIRGLRG-WTRVPILVLSARHSSDEKVEALDAGADDYVTKPFGMDELLARLRAAVRRA--
+----TRVLVVDDEPQIVRALVINLKARKYE-VDAAGDGRTALDLAASRHPDVIVLDLGLPDMDGVEVIRGLRG-WTRVPILVLSARHSSDEKVEALDAGADDYVTKPFGMDELLARLRAAVRRA--
+----TRVLVVDDEPQIVRALVINLKARKYE-VDAAADGAGALELAAARHPDVVVLDLGLPDMDGVEVIRGLRG-WTRVPILVLSARHSSDEKVEALDAGADDYVTKPFGMDELLARLRAAVRRA--
+----TRVLVVDDEPQIVRALVINLKARAYE-VDAAHDGATALALAAARHPDVVILDLGLPDMDGVEVIDGLRG-WTRVPIIVLSARHTSDEKVEALDAGADDYVTKPFGMDELLARLRAAVRRA--
+----TRVLVVDDEPQIVRALQINLKARRYE-VHVAGTGTAALQVAAQHPPDLVILDLGLPDLDGIEVIRGLRG-WTEAPILVLSGRTDSTDKVEALDAGADDYVTKPFGIDELLARMRAALRRS--
+----TRVLVVDDEPQIVRALELNLRARQYE-VDSAGDGTTALRLAAERHPDVIVLDLGLPDMDGVDVLRGLRS-WSRVPVLVLSARQSSDEKVQALDAGADDYVTKPFGMDELLARLRAAVRRT--
+----TRVLVVDDEPQILRAMRINLSARGYE-VVTASSGAGALRAAAETQPEVVILDLGLPDMDGTEVLAGLRG-WTDVPVIVLSARTDSADKVEALDAGADDYVTKPFGMDEFLARLRAAVRR---
+----TRVLVVDDEPQILRALRINLTARGFD-VTTASTGAGALRAAAERQPEVVVLDLGLPDMDGFEVLAGLRG-WTNVPVIVLSARTDSSEKVDALDAGADDYVTKPFGMDELLARLRAAVRR---
+----TRVLVVDDEPQILRALRINLSVRGYE-VTTASTGAAALRAAAERHPEVIVLDLGLPDMDGIEVLAGLRG-WCTAPVIVLSARTDSSDKVEALDAGADDYVTKPFGMDEFLARLRAAVRR---
+----TRVLVVDDEPQILRALRINLSVRGYD-VVTAASGAAALRAAAERPPDVIVLDLGLPDMDGTEVLAGLRG-WCPAPVIVLSARTDSADKVEALDAGADDYVTKPFGMDEFLARVRAAARRAT-
+----TRVLVVDDEPQILRALRINLLARHYE-VAVAADGGAALREAADWRPDLVILDLGLPDIDGVDVIHGLRG-WTSIPIVVLSGRAGGADKVDALDAGADDYVTKPFNIDELLARIRAVTRRTA-
+----TRVLVVDDEPQILRALRINLLARHFE-VAVAPDGGSALRQAADWHPDLVVLDLGLPDIDGVDVIHGLRG-WTAVPIIVLSGRAGNQDKVEALDAGADDYVTKPFNIEELLARMRAVTRRTA-
+----TRVLVVDDEPQILRALKINLSVRGYE-VVTAATGAGALRAAAEHRPDVVILDLGLPDISGIEVLAGLRG-WLTVPVIVLSARTDSADKVEALDAGADDYVTKPFGMDEFLARLRAAARRN--
+----TRVLVVDDEPQILRALKINLSVRGYE-VTTAATGAEALRSAADHKPDVIVLDLGLPDMSGIEVLAGLRG-WLSAPVIVLSARTDSSDKVEALDAGADDYVTKPFGMDEFLARLRAAVRRAT-
+----TRVLVVDDEPGIVRALVINLRARAYE-VDAAHDGATALRLAAAHRPDVIVLDLGLPDMDGVEVIRGLRGR-TRVPILVLSARHASDEKVGALDAGADDYVTKPFGMDELLARLRAAVRRA--
+----TRVLVVDDEPAVRSFMGQSLRLAGYD-AWEFDGPAAAVEALDREDVALVVTDVQMRGSSGPTFARRLRLTHPSLPVLFVSGFAPEELDLEGGARRA--FLAKPFGRATLLDAVATLIAEA--
+----TRVLVVDDEPALVRALVINLKARSYE-VDAAHDGAGALELAAARHPDVVVLDLGLPDMDGVEVIKGLRG-WSRVPILVLSARHASAEKVQALDAGADDYVTKPFGMDELLARLRAAVRRA--
+----TRVLVVDDDRAVRESLRRSLSFNGYS-VSLATDGVEALEAISNERPDAMILDVMMPRLDGLEVCRQLRSTGDDLPILVLTARDSVSERVAGLDAGADDYLPKPFALEELLARMRALLRRTT-
+----TRVLVVDDDPTVSNVVSAYLTKAGYD-ARVVPDGVKAVEVWQQWKPSVVVLDVMLPGLSGLEVLRRLRSADDGAAVIMLSARGEEEDRLVGLEVGADDYVVKPFSPRELVLRVQALLRRE--
+----TRVLVVDDDPTVAEVVDRYLRNAGFD-VDRAADGLTALRMAETTVPDLVVLDLMLPGIDGIEVCRRLREQ-RPVPVIMLTARGEEADRVAGLETGADDYVTKPFSPRELTLRVRSVLRRA--
+----TRVLVVDDDPHIRELVGHFLRLEGLE-VVEAVDGLDAMRLFDETKVDLLVLDIMMPGMDGWELCRKLREQ-TDLPLLMLTAKGETSQIVKGFALGTDDYLVKPFDPMVLVARVKALLKRY--
+----TRVLVVDDDITARLMARQALGKENFA-VIEAEDGFAALALFEAVQPDIVLLDVEMPGMNGFEVCRQLRRCGKLVPILMATGQDDLDSVRQAYEAGATDFVTKPFNWKILAHRLRYMVRAS--
+----TRVLVVDDDAGVRFTLREMLKSLGVE-VDEAVDGEDALEKLSARPYELVISDLRMPRMDGMELVRRLSLFSRSPRVIVITAHGSERFAVEAMKAGAYDYFRKPFDVDELLAVVSRALESV--
+----TRVLVVDDDADFGDMILAMLEHRGVE-AAVVSSPLDALEVLRDHPWDVMVTDQTMPGMRGIDLVKAVKAIRPDLPCLICTGYPEALDEAALTKAGVFALLHKPVDFPHYFAQLARAL-----
+----TRVLVVDDDADACGFLTRALGGEAML-VHTAANGNAALDALTSFAPDAVLLDVDMPGMDGFAACTALLDRHADLPVIFMTGLGDTGHIVRGFEVGACDYVTKPVAIAEVVARVRSHAG----
+----TRVLVVDDAKFMRVKIRESLEEANYIIAGEAADGEQAADLYKKLRPDLVTMDITMPVKNGIKALRDILTFDPKAKVIMCTAMRQQRIVTEAIELGAKDFIVKPFEETKVLEAVSRVM-----
+----TRVLVVDDAKFMRVKIREILESANYTVAGEAADGEEALAVYQKIRPDLVTMDITMPVKNGIQALQDILAFDPKARIIMCTAMRQQRIVLEAIELGAKDFIVKPFEASKVLEAVGRV------
+----TRVLVVDDAKFMRVKIREILESANYIVAGEAADGEEALAVYQKIRPDLVTMDITMPVKNGIQALQDILAFDPKAHVIMCTAMRQQRIVLEAIELGAKDFIVKPFEASKVLEAVGRV------
+----TRVLVVDDAKFMRVKIREILEEANYIIAGEAADGEQAADLYKKLRPDLVTMDITMPVKNGIKALRDILTFDPKAKVIMCTAMRQQRIVTEAIELGAKDFIVKPFEETKVLEAVSRVM-----
+----TRVLVVDDAKFMRVKIREILEEANYIIAGEAADGEQAADLYKKLRPDIVTMDITMPVKNGIKALRDILTFDPKAKVIMCTAMRQQRIVTEAIELGAKDFIVKPFEETKVLEAVRRVM-----
+----TRVLVVDDAKFMRVKIREILEAANYIVAGEAADGEEAADLYQRLRPDLVTMDVTMPLKNGIQALQEIMSFDPKANVIMCTAMRQQRIVVEAIELGAKDFIMKPFEESKVLEAVNRVM-----
+----TRVLVVDDAAFMRMMVKDILSKNGYEIVGEAENGMKALEKYQELKPDLVTMDITMPEMDGITAVKEIKKVDPAAKVVMCSAMGQQAMVIEAIQAGARDFIVKPFQADRVLEAIRKAV-----
+----TRVLVMDDDRIQQGITREMLSRSRIH-CDCCTDVRELMDCLKSQEYDLLLTDIQMPGADGFSILELLRGRAREIPAIAVTAHSD--REEEYLFAGFAGCIHKPFSAEGLVTAIMRVIKG---
+----TRVLVIEDEPQIVRALVINLKARKYE-VDTAHDGAGALRLAAARHPDVVVLDLGLPDMDGVEVIRGLRG-WTRVPILVLSARHSSDEKVEALDAGADDYVTKPFGMDELLARLRAAVRRA--
+----TRVLVIDDEPQIVRALVINLKARHYE-VDAAHDGATALQLAAARHPDVVVLDLGLPDMDGVEVIRGLRG-WTRVPILVLSARHSSDEKVEALDAGADDYVTKPFGMDELLARLRAAVRRA--
+----TRVLVIDDEPQILRALRINLSVRGYE-VVTASTGAGALRAAAEHKPDVVILDLGLPDISGIDVLAGLRG-WLTAPVIVLSARTDSSDKVEALDAGADDYVTKPFGMDEFLARLRAAVRRN--
+----TRVLVIDDEPQILRALRINLSVRGYE-VVTASSGAGALRAAAEHKPDVVILDLGLPDISGIDVLAGLRG-WLTAPVIVLSARTDSSDKVEALDAGADDYVTKPFGMDEFLARLRAAVRRN--
+----TRVLVIDDEPQILRALRINLSVRGYE-VITASSGAGALRAAAEHKPDVVVLDLGLPDISGIDVLAGLRG-WLTAPVIVLSARTDSSDKVEALDAGADDYVTKPFGMDEFLARLRAAVRRN--
+----TRVLVIDDEPQILRALRINFSVRGYD-VVTAATGAAALRAAAEQRPDVVILDLGLPDMSGIEVLAGLRG-WFSAPVIVLSARSDSSDKVQALDAGADDYVTKPFGMDELLARLRAAVRRAA-
+----TRVLVIDDEPHILRALRINLTVRGYE-VITASTGAGALRAAAEHPPDVVILDLGLPDISGIDVLAGLRG-WLTAPVIVLSARTDSSDKVEALDAGADDYVTKPFGMDEFLARLRAAVRRNA-
+----TRVLVASANAAFADFLCATLQEAALR-AEAACSGVAVEQALARDPFAFLLMDADLPEPGGFALAQRFAAARPDRIIPMMASHSQRNDALRCEELGLGYRLAKPFSAEDLLAVLRM-------
+----TRVLVAEDEALIRLDLVEMLGEQGYEVVGQASNGQQAVELAKELRPDVVIMDVKMPVLDGLSAAEQLHEA-KLCPVIMLTAFSQTELVERARDAGVMAYIVKPFTADDLRPAIDI-------
+----TRVLVADDQDLVRTGLSMILDQPDIEVVGQAADGKAAVELAHRLRPDVCLVDIRMPGLDGIEVTELLAGRADPIAVVVITTFDLDEYVHGALRAGARGFLLKDAGPALLVQAVHAA------
+----TRVLVADDQAMVRGSFRVLVDTPGLSAVGEAADGAEAVELARRERPDVVLMDIRMPGLDGIGATRRICAATAGVRVLILTTFDLDEYVYAALRAGAAGFLLKDTPPSRVLDAITVV------
+----TRVLVADDNFTSRAILKEVLESLRFD-VTLAESGEEAVDLVQKEPFKVVLLDWRMPGLDGLACARHIRQLDLPVRILIITAYGREEVLGEIPSEIIDGVLLKPVARSLLLNTILDALP----
+----TRVLVADDHPEALEILVYMLTQLQCS-VTAVSGGLEAVGAVSMTPFELVLMDWEMPKTNGLDAAQLILSETAPPKLILISGTH-LKNSEILKKYGFIGFIAKPITPVSLKTSLEEILNQH--
+----TRVLVADDHALVRDGLRHILKASGFEVVGEASDSASTVALIRTCAADVLVLDLSMPGRNGVELIKQIKDEKPALRILVLTMHAEQQYAVRAFKAGASGYLTKESASAELVSAVAKVA-----
+----TRVLVADAHPLLLRGVQHLLREPDLSIIGEAISGAQALRLASDLQPDIAILDVALPGLHGSEIRQRLAERAAGTRVIILSGTEEPICAQRALAAGVCGYVLKRSAPETLLHAIRAV------
+----TRVLLVRDEQVNLELIRAGLAEAGFVDVGVVDADLMLPERIAQTQPDMVIVASESAARDTIEHVCVATQH-APRPIVLFTDNDDASRIKAAFAAGITAYIVDGLKPTRVKAVLDVAYAR---
+----TRVLLVRDELVNLELIRAGLAEAGFVDVGVVDADLMLPERIAQTQPDMVIVASESAARDTIEHVCVATQH-APRPIVLFTDNDDASRIKAAFAAGITAYIVDGLKPTRVKAVLDVAYAR---
+----TRVLLVEDNELNRDMLSRRLKRSGFE-VLFAEDGQQAVDTAAAEMPDLILMDLSLPTMDGFEATRALRAKTAGLRVIALTSHAMSGDRERALAAGCDDYDTKPVDLPRLLGKMHALLD----
+----TRVLLVEDESLVAMLLEDCLTELGYEVAATVGDVDTALEVVQQGNLDLAVLDVNLGGVLSFPIAEELDTR--GVPYIFVTGYAQGGIPEKFRHRH---GLQKPFQFRDLKEALSVLER----
+----TRVLLVEDDQRIRQALGLALADIGFE-VVEADSGDQALDRLDHLVVDVVLLDLMLPGVDNLTVCRIPRS-CGDLPIIIDSARTDTEGVIEGLESGADD------------------------
+----TRVLLVEDDPAISEPLARALGREGYE-VLASSTGREALTNVE--GADLVVLDLGLPDMDGLDVAREIRADGGRVPILILTARTDEVDMVVGLDAGADDYVTKPFRLAELLARVRALLRRHT-
+----TRVLLVEDDPAIAEPLTRALQREGYE-VGAHVTGGSALKQVN--DSDMVILDLGLPDMDGLDVARTIRAQGITIPILILTARTGEVDMVVGLDAGADDYVTKPFRLGELLARVRALLRRSG-
+----TRVLLVDDSPVDRRVVQLLLSSSSFH-VIAVDSAKKAMEFLKEQAIDMVLTDYCMPEMTGYELLKAIKALLKPIPVIVMSSENEPQRISRCMNAGAEDFIVKPLQSKDVQR-----------
+----TRVLLVDDSPVDRRVVQLLLSSSSFH-VIAVDSAKKAMEFLKEQAIDMVLTDYCMPEMTGYELLKAIKALLKPIPVIVMSSENEPQRIS---------------------------------
+----TRVLLVDDSPVDRRVVQLLLSSSSFH-VIAVDSAKKALGFLKEQAIDMVLTDYCMPEMTGYELLKAIKALLKPIPVIVMSSENEPQRISRCMNAGAEDFIVKPLQSKDVQR-----------
+----TRVLLVDDQAVVRAGYAVILASEGLDVVGDAASGREAVQRARELRPDVVVMDVRMPGGDGITATRELAGAVDPVPVLVVSTFDLDEYVFGALEAGAGGFLLKDAEPEVLAAAVRRVAA----
+----TRVLLVDDNYTVREVLARRLQSFGID-AVMASNGPEGLDYLVANAYDLLFVDSDMPDITGVDFLSKAQQKLPSRVAVMFSAGCTEEERQNARLVGADYTLIKPVFDADLIRCLASV------
+----TRVLLVDDNPINRAVATEMLHAAGVE-VEAVPSGETALDTLANVAFDAVLLDIQMPGMDGYQTAAAIRARRPGAPVIAFTARVEGEDEEALHRAGIVGRLPKPVDRQELLATLHRHL-----
+----TRVLLVDDHPVVRRGVRATIEDETITVAGEAGSGEQALALLAELAVDVVLLDLQLGGIDGAETTRRIQRLPRPPRVLVLTTYDTDADILPAIEAGATGYLLKDTDPAELIAAIHAAA-----
+----TRVLLVDDHPVVRAGLRAVLESLGITVCAEAQDGRAALERLGTHGVDVVVMDLQMGGMGGLEATRRIVAS-GGPPVLILTTYDTQADVVAALEAGATGYLLKDAQPETIGQAVHDAA-----
+----TRVLLVDDEPELLEAWSFALEYVGYD-VERARDGRQALAAIERQPPDLLITDLMMPGMNGEDLCRALRSRWAEIPILLHTSAYIGANDGAAL---WNAVLRKPARIEDFLATVAKLT-----
+----TRVLLVDDELLAREILRDYLSDSSIEVVGEASDGRVAVVQAASLRPDVILMDMQMPVMDGVAATAQIHAEFPDIAILGLSTFSTDRYVVDLLRAGASGYLVKDTLPKEITAAIHTVMA----
+----TRVLLVDDEKNVLSALRRALFDDPYE-IMTASSAEEALEIMKLHSFKVVISDERMTGMQGVDFLARVRVLSPETVRILLTGHGTMEAAMKAVNLGIYRFFTKPWNDLEIRFAVRSAVEKY--
+----TRVLLVDDDRELTEMLSQYLTRESFT-VTCTNSAEEGENEALSGRHDIVVLDIMMPRMSGIEVLRRIRAQ-SQVPVILLTARGDNIDRISGLELGADDYVPKPSSPGELVARLRAIMRRV--
+----TRVLLVDDDRELTEMLSQYLTRESFT-VTCTNSAEEGEIEALSGRHDIVVLDIMMPRMSGIEVLRRIRAQ-SQVPVILLTARGDNIDRISGLELGADDYVPKPSSPGELVARLRAIMRRV--
+----TRVLLVDDDQTILSLLKRGLAYEGFE-VYTAPDGETGLAATKKYQPHLVLLDIAMPGLDGLELCRRLHVL-GDIAIIMLTARDDVADKVHALGLGADDYVPKPFSFDELVARMRAVLRRHT-
+----TRVLLVDDDPLVRAGLRLMLESAGLDVVGEVGDGAEVVDAVARWAPDVVLMDIRMPVLDGIAATRALVDRPGATPVLVLTTFGADRTVVDALRAGAAGYVLKDTPPAEIVEAVRRVAA----
+----TRVLLVDDDPLVCGALATMLGSADLNVVGSVNDGDQVVEAIHRHRPDIILMDVRMARQDGITTTASLSGLETPPKVIMLTTFDHDDVMLRAVHAGAAGFLLKTASPLDIIAAVQSVAA----
+----TRVLLVDDDAELTGMLVQYLGHEGFA-AEVAHDGEAGVARALSGDFAIVVLDVMMPRLSGIDALRRIRAA-SQVPVVMLTARGDNIDRISGLDLGADDYVPKPCTPGELVARLRAILRRT--
+----TRVLLVDDDAELTGMLVQYLAHEGFA-AEVAHDGEAGVARALSGDFAIVVLDVMMPRLSGIDALRRIRAA-SQVPVVMLTARGDNIDRISGLDLGADDYVPKPCTPGELVARLRAILRRT--
+----TRVLLIEDNVDLAKTIIQFLTLEGFD-TDYVGNGHAGFNFAVKNKYDVFILDINLPGLDGLSVCQKLRSQGIDAPILMLTARGTLFDKLAGFDAGTDDYLIKPFALDELLARLRALAKRK--
+----TRVLLIEDEPLIAMDTESHLVSAGCEVVGLAATIEEARQLIADKVFDIALVDANLSGEPVDEIAVALAR--KGIPFAFATGYGAEALPPAFRDAP---ILTKPFSPQALLAEVAALRAR---
+----TRVLLIEDDRDLAETLLQLMEFENMV-PDYASNGVAGLTLAQSNRYDILVIDIGLPKMNGLTLCEQLRQEGCQTPILFLTARGSIDDKLAGFASGGDDYLSKPFDNRELLARIMVLS-----
+----TRVLLIEDDPAVRRGVTLGLRRRGHE-TEAVATGEDGLEALAASPPDLVLLDLMLPGMSGLEVCRRIRET-SQVPVVILSARGDDIDVVVGLEAGADDYIVKPSSDEVIEARMRAVMRRL--
+----TRVLLIDDDTRMYELLEQYLGQNGLS-VTHAADGGRGLAALEASAFDAVLLDVMMPGMDGLEVCKRIRAK-SRIPVIMLTAKGDETDRVVGLELGADDYLPKPFSPRELLARLRAVLRRS--
+----TRVLLIDDDTRMYELLAQYLGQNGIS-VAHAPDGGRGLAALEGSPYDAVLLDVMMPGMDGLEVCKRIRAK-TQVPILMLTARGDETDRVVGLELGADDYLAKPFSPRELLARLRAVLRRA--
+----TRVLLIDDDLEFTGLLCEYLTDEGFD-VLSTDDGAKGLAFVDSGATDIIVLDVMMPIMNGVDVLQNIRKS-SEIPIVMLTARGDDKDRITGLDLGADDYVSKPCSPGELVARLRAILRRTG-
+----TRVLLIDDDARLTHMVRDYLQAAGHV-VSVAGDLAGGRGLLQRESFDALILDLMLPDGDGLDLTRELRARWRSLPLLMLTARGEPLDRIVGLELGADDYLPKPFEPRELLARLKALLRRAS-
+----TRVLLAEDNDLNAEIAVALLDMQGVE-ARRAANGREAVDMFEASEFDFVLMDVKMPLLDGLEAAIEIRSDARTVPIIALTANTFQEDREDAAAAGMDGFIPKPFDAQQLYETLRSYLPRK--
+----TRVLLAEDNDLNAEIAVALLDMQGVE-ARRAANGREAVDMFDASEFDFVLMDVKMPLLDGLEAAIEIRADARTVPIIALTANTFQEDREDAAAAGMDGFIPKPFDAQQLYETLRSYLPRK--
+----TRVLLAEDNATNQIVGAMILRNLGCL-VDVATNGREAMEMVDAFLYDMVFMDCEMPEMDGFEATAALRRRKSRLPVIAVTAQAMQGDRERCLRAGMDDYISKPVKLEDFAAALKRWM-----
+----TRVLLAEDNAALAQMLQTFLAAQGME-TIIAGTGTEAMRVLASSPVDLLLLDLKLPELSGVEVLQRLRKELASLPVIIMTGYRGEKYALGAQKLGVRHYLEKPFSRQAFLNAVHSSLT----
+----TRVLLAEDDPAISEPLARALRREGYE-VEVRADGREALEAARE-NPDLVVLDLGLPTMDGLEVCRRLRGEGHTVPVLVLTARADEVDTVVGLDAGADDYVTKPFRLAELLARARALLRR---
+----TRVLLAEDDPAISEPLARALRREGYD-VDVREDGAEALEGAK-DNPDLVLLDLGLPKVDGLEVCRRLRAEGRSIPVLILTARADEVDTVVGLDAGADDYVTKPFRLAELLARVRALLRRT--
+----TRVLLAEDDEAIASPLARALTREGYD-VTVAATGTDAVRRALDEEFALLILDLGLPELDGLEVCREVRAARPEVAVLMLTARTDEMDFVVGLDAGADDYVGKPFRMFELMARTRALLRRS--
+----TRVLLAEDDASISEPLARALRREGYE-VEVRQDGPTALDAGLRGGVDLVVLDLGLPGMDGLEVARRLRSDGHTVPILILTARADEVDTVVGLDAGADDYVTKPFRLAELLARVRALLRRG--
+----TRVLLAEDDASISEPLARALRREGYE-VEVRQDGPTALDAGLQGGIDLVVLDLGLPGMDGLEVARRLRAGGHTIPILVLTARADEVDTVVGLDAGADDYVTKPFRLAELLARVRALLRR---
+----TRVLLAEDDASISEPLARALRREGYE-VEVREDGPTAVDAGLQGGIDLVVLDLGLPGMDGLEVARRLRSEGHAVPILILTARADEVDTVVGLDAGADDYVTKPFRLAELLARVRALLRRG--
+----TRVLLAEDDASISEPLARALRREGYE-VEVREDGPTALDAGMQGGVDLVVLDLGLPGMDGLEVARRLRSEGHTVPILILTARADEVDTVVGLDAGADDYVTKPFRLAELLARVRALLRR---
+----TRVLLAEDDASISEPLARALRREGYE-VEVREDGPTALDAGMQGGVDLVVLDLGLPGMDGLEVARRLRAEGHTIPILILTARADEVDTVVGLDAGADDYVTKPFRLAELLARVRALLRRG--
+----TRVLLAEDDASISEPLARALRREGYE-VEVREDGPTALDAGMQGGIDLVVLDLGLPGMDGLEVARRLRAEGHTVPILILTARADEVDTVVGLDAGADDYVTKPFRLAELLARVRALLRRG--
+----TRVLLAEDDASISEPLARALRREGYE-VEVREDGPTALDAGMQGGIDLVVLDLGLPGMDGLEVARRLRAEGHAVPILILTARADEVDTVVGLDAGADDYVTKPFRLAELLARVRALLRRG--
+----TRVLLAEDDASISEPLARALRREGYE-VEVREDGPTALDAGLQGGVDLVVLDLGLPGMDGLEVARRLRGEGLAVPILVLTARADEVDTVVGLDAGADDYVTKPFRLAELLARVRALLRR---
+----TRVLLAEDDASISEPLARALRREGYE-VEVREDGPTALDAGLQGGVDLVVLDLGLPGMDGLEVARRLRAEGHTVPILVLTARADEVDTVVGLDAGADDYVTKPFRLAELLARVRALLRRG--
+----TRVLLAEDDASISEPLARALRREGYE-VEVREDGPTALDAGLQGGVDLVVLDLGLPGMDGLEVARRLRAEGHGFPILVLTARADEVDTVVGLDAGADDYVTKPFRLAELLARVRALLRR---
+----TRVLLAEDDASISEPLARALRREGYE-VEVREDGPTALDAGLQGGVDLVVLDLGLPGMDGLEVARRLRADGHAVPILVLTARADEVDTVVGLDAGADDYVTKPFRLAELLARVRALLRRG--
+----TRVLLAEDDASISEPLARALRREGYE-VEVREDGPTALDAGLQGGVDLLVLDLGLPGMDGLEVCRRLRTEGHGFPVLVLTARADEVDTVVGLDAGADDYVTKPFRLAELLARVRALLRRG--
+----TRVLLAEDDASISEPLARALRREGYE-VEVREDGPTALDAGLAGGVDLVVLDLGLPGMDGLEVARRLRAEGHTIPILVLTARADEVDTVVGLDAGADDYVTKPFRLAELLARVRALLRRG--
+----TRVLLAEDDASISEPLARALRREGYE-VEVREDGPGALEAGMQGGVDLVVLDLGLPGMDGLEVARRLRAEGHTVPLLILTARADEVDTVVGLDAGADDYVTKPFRLAELLARVRALLRRG--
+----TRVLLAEDDASISEPLARALRREGYE-VEVREDGPAALEAGMRGGIDLVVLDLGLPGMDGLEVARRLRSEGHTVPLLILTARADEVDTVVGLDAGADDYVTKPFRLAELLARVRALLRR---
+----TRVLLAEDDAAISEPLARALRREGYE-VTVRADGPGALLA-GQSGVDLVVLDLGLPGMDGLEVCRRLRADGHTFPVLVLTARADEVDTVVGLDAGADDYVTKPFRLAELLARVRALLRR---
+----TRVLLADDQPLIRAGYRMILDSEDLEVVGEAVNGREAVFLARTTRADVVLMDIRMPEVDGIEATRRIAADLAGVRILVLTTFEEDENVLRAVRAGAAGFLGKNVGPAELLHAVRTVA-----
+----TRVLLADDQPLIRAGFRVLLDEDDIDVVGEASTGAEAVDLARETVPDIALVDVQMPEMDGIEATRRIAAALSSVRVVILTNYALDEYIFDALRAGASGFLVKDTEPEELIRAVRTVA-----
+----TRVLLADDHALVRDGLRHILRASGFDVLGEASDSASTVALIRACAADVLVLDLSMPGRNGVELIKQIKDEKPSLRILVLTMHAEQQYAVRAFKAGASGYLTKESASAELVAAVTKVA-----
+----TRVLLADDHALVRDGLRHILKASGFEVVGEASDSVTTVALIRACPAEVLVLDLSMPGRNGVELIKQIKDEKPALRILVLTMHAEQQYAVRAFKAGASGYLTKESASAELVAAVTKVA-----
+----TRVLLADDHAAIRAGLRLLLEQGGIEVVGEAADGQAAITNARALRPDVVLMDVRMPGVDGIEATRVITRE-GLADVVALTTFDLDEYVLGMLRAGAVGFLLKTTGAAALVDAVQRVAA----
+----TRVLIVEDQSMPRTLFEMYVNSENYTLAGSISNADMTDYHCENSDVDLILMDICTSGANGLEAAERIKAKFPKIKIIIVTSMPEYSYLKRAKEAGVDSFWYKEVSPEPIIELMDRTMN----
+----TRVLIVEDEPDLADPLAYLLRREGYE-VEIAEDGALALSAFHDRGADIVLLDLMLPGMPGTEVCRQLRLS-SHVPIIMLTAKDSEVDIVVGLELGADDYVTKPYSTRELLARMRAVLRRR--
+----TRVLIVEDEESMAEPLAFLLRKEGFS-TEIATNGPDALETFDRVGADIVLLDLMLPGMSGTEVCKQLRGR-GAVPVIMVTAKDSEIDKVVGLELGADDYITKPYSTRELIARIRAVLRR---
+----TRVLIVEDEESLADPLAFLLRKEGFE-TVIAGDGPTALTEFDRTGADIVLLDLMLPGMGGNDVCKQLRAR-SSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELTARIRAVLRR---
+----TRVLIVEDEESLADPLAFLLRKEGFE-TVIAGDGPAALTEFDRSGADIVLLDLMLPGMGGNDVCKQLRAR-SSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELTARIRAVLRR---
+----TRVLIVEDEESFADPLAFMLRKEGFT-TAVAANGNDALSEFDRNGADIVLLDLMLPGMSGTDVCKALRSR-SAVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARVRAVLRRG--
+----TRVLIVEDEESFADPLAFLLRKEGFT-AAVAVTGQQALEEFDRNGADIVLLDLMLPGMSGTDVCKQLRQR-SAVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARVRAVLRRG--
+----TRVLIVEDEESFADPLAFLLRKEGFT-AAVATTGQSALEEFDRNGADIVLLDLMLPGMSGTDVCRSLRSR-SAVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRG--
+----TRVLIVEDEESFADPLAFLLRKEGFT-AAVATTGQEALEEFDRNGADIVLLDLMLPGMSGTDVCKQLRQR-SAVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARVRAVLRRG--
+----TRVLIVEDEESFADPLAFLLRKEGFT-AAVAGTGQAALEEFDRNGADIVLLDLMLPGMSGTDVCKQLRQR-SAVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARVRAVLRRG--
+----TRVLIVEDEESFADPLAFLLRKEGFT-AALAATGPEALEEFDRNGADIVLLDLMLPGMSGTDVCKQLRQR-SAVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRG--
+----TRVLIVEDEESFADPLAFLLRKEGFT-AAIATDGQQALEEFDRNGADIVLLDLMLPGMSGTDVCRELRQR-SSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARVRAVLRRG--
+----TRVLIVEDEDSLADPLAFLLRKEGFE-VGVAGDGPSALESFESEGADIVLLDLMLPGMSGTDVCKRLRMT-SSVPVIMVTARDSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRR---
+----TRVLIVEDDTIIAMTAEDMLDECGCKTAAIAVSVAEALARAADTDFDIALLDLNLKDENSLPVAQHLRDA--GKRFIFATGYDGLPAD-----SGFADVISKPYRIEQLATVIAQTL-----
+----TRVLIVEDDIDIRGILARGLEAEGFS-VGVAGRVEDALSAARDEAPEAVVLDITLPDGSGHDVCRSLREGGYPGAILFLSARDEVRDRAEGLALGADDYIVKPFVFDELLARLQVHLL----
+----TRVLIVEDDIDIRGILARGLEAEGFS-VGVAGRVEDALSAARDEAPEAVVLDITLPDGSGHDVCRSLREGGYPGAILFLSARDEVRDRAEGLALGADDYIIKPFVFDELLARLQVHLL----
+----TRVLIVEDDIDIRGILARGLEAEGFS-VGVAGRVEDALSAARDDAPEAVVLDITLPDGSGHDVCRSLREGGYPGAILFLSARDEVRDRAEGLALGADDYIVKPFVFDELLARLQVHLL----
+----TRVLIVEDDIDIRGILARGLEAEGFS-VGVAGRVEDALSAARDDAPEAVVLDITLPDGSGHDVCRSLREGGYPGAILFLSARDEVRDRAEGLALGADDYIVKPFVFDELLARLQTHLLR---
+----TRVLIVEDDEILGDELRDVFTQWGFE-ASLVASVHDFWANVEDYQPQLVVVDLTLPDGSGVDIIRDVRSK-SDIGIIVMSGRSDEIERVVCIETGADDYVVKPFSSREMVARIRQLMYRT--
+----TRVLIVEDDEDIASVIARGLQREGYE-TLCAADVRAARDAMVAEMPDAAIVDMMLGEESGSKLVADLRAKGVRIPIIMLSALSRVSDRTAGLVAGADDYVVKPFEFKELVARLK--------
+----TRVLIVEDDDRLRRTLAINLQARRHE-VHTAADGGTGLELAATIHPDLVILDLGLPDMDGVEMVSLLRRR-SAVPVIILSARDAEATKVAALDAGADDYVTKPFGMEELLARMRAAVRRA--
+----TRVLIVDDSHTMCALVQLELSDPELEVVAVAHNARDARDAIDQFKPDVLTLDIEMPGMDGLEFLSRVMKH-RPTPVVMVSSLTNKDLSVEALSRGAVDLFAKPG------------------
+----TRVLIVDDSEFMRSLLREILAE-DYEIVGEAENGVEAVELYEEHDPDLVMMDIVMPIRDGIEATTAITAGDADARVIMCTSVGQEEKMKMAVKAGASGYITKPFQKPSVLQAIDDVV-----
+----TRVLIVDDSALVRRILSEALSKHDIEVVGTATDPYVARERIAQLKPDVITLDIEMPRMDGLSFLSKLMRHF-PLPVVVCSSLTNSETALRALALGAVEVIAKPGSS----------------
+----TRVLIVDDQAMVRAGFAALLAQSDIDVVGEAPDGARGVELSRRTHPDVVLMDVRMPEMDGLEAARRLLTVTHVPRVLMLTTFDIDDYVYEALRAGASGFLLKDAPPADLIAAVRVVA-----
+----TRVLIVDDHPMVAEGIRSLLESYDLEIVGTLGNGQDAVDQAIALGPDVILMDLNMPGLSGLAATEMILEKQPDTRIVILSMHDSPEYISTALSHGARGYILKDVPTEEIHTAIETVM-----
+----TRVLIVDDEPQILRAMRINLRARGYE-VVVADTGATALTAAAETRPDIVILDLGLPDLDGVEVIHGLRG-WTRVPIVVLSGRADSRDKVGALDAGADDYITKPFGIDELLARLRAVARRTG-
+----TRVLIVDDDTQILRALRITLHARGYE-VMTATSGRHALAATTSGRPDIILLDLGLPDMDGAEVIHALRS-WTTTPVIVLSGRGGSTDKVGALDAGADDYVTKPFRVDELLARLRAVARRT--
+----TRVLIVDDDPTILEAFPVYLSTDDLKVVGTATTGRQALQWLETNSSDLVLSDIHMPDTDGIELLQHTQQLPQPPLFVAMTAFDTDETMLKCLSLGAVGYIIKGQAPESIIHSLRDAIH----
+----TRVLIVDDDPMVRRLLTAVLRGQGIDVVGEATDGDEVPAAVDAHRPDVVLMDLHMRRVGGLDAIRALRRRTDPPAVIALTSFGSDDTVVAALDAGAQGFLGKDDDPDRIANHVRQVAA----
+----TRVLIVDDDFMVARVHAGFVAALGFEVVGTASSGAAALAEVARLRPDLVLLDVYLPDMTGLEVLRRLRADAVPVDVVVISAARDVESIRSARHGGVLSYLVKPFDRQTFEARLREYA-----
+----TRVLIVDDAKFMRDKIREILETEDLQVAGEAENGEEAVLLYQELQPDLVIMDITMPVKNGIEALKDMIQLNPKVKVIMCTAMRQKRIVVEAIEAGAKDFIVKPFEETKVVEAIRHVLGN---
+----TRVLIVDDAAFMRMMVKDILSKNGYEIVGEAENGMKALEKYQELKPDLVTMDITMPEMDGITAVKEIKKVDPAAKVVMCSAMGQQAMVIEAIQAGARDFIVKPFQADRVLEAIRKAV-----
+----TRVLIVDDAAFMRMMLKDILTKNGFEVVGEAENGKMAVQMYSELKPDVVTMDITMPEMDGLAAVKEIKQQDPNAKVVMVSAMGQQAMVIEAIRAGAADFIVKPFQPDRVLEALSKAL-----
+----TRVLITDDSALARKQLARSLPSTIHADVTFAENGKIAIEQLQASRFDVMFLDLTMPEMDGFETLEMMRTNNINVPVFVVSGDIQPKAQERVLSLGAKAFVRKPVSQENLAQLLV--------
+----TRVLILADAPVLRRGLVSMINTAGMQSVGTPGELRRALTLVETARPDTVVVELGQGRAATLNACRDLRRRFPRVTIVALGTSEDPAVVNEALAAGVRGYLMINTSPT---------------
+----TRVLIIEDEWVIALDLKTLVTDLGHEVVGVAPTHTKALELAKDGDFGLVLADIQLAGSSGIDAVTDILGS-FDVPVIFITAFP--DRLLTGERPEPTYLITKPFLSETVKATIAQAL-----
+----TRVLIIEDEWVIALDLKTLVSELGHEVIGVAPTHAKAVELAKAGNFGLVLADIQLAGSSGIEAVTEILES-FNVPVIFITAFP--DRLLTGERPEPTYLITKPFLTETVKATIAQAL-----
+----TRVLIIEDEESYREATAFMLRKEGFE-VNTAANGADGLEIYSRNGADIVLLDLMMPGLPGTEVCRQLRQR-GNVGIIMVTARDSEIDKVVGLELGADDYVTKPFSHRELVARIRAVTRR---
+----TRVLIIEDEESYREATAFMLRKEGFE-VNTAANGADGLEIYSHNGADIVLLDLMMPGLPGTEVCRQLRQR-GNVGIIMVTARDSEIDKVVGLELGADDYVTKPFSHRELVARIRAVTRR---
+----TRVLIIEDEESYREATAFMLRKEGFE-VDTATSGSDGLETYSRNGADIVLLDLMMPGLPGTEVCRQLRQR-GNVRIIMVTARDSEIDKVVGLELGADDYVTKPFSHRELVARIRAVTRR---
+----TRVLIIEDDVAIAQLHHKYLNQMGFDVVGIATSQAEAEMQLEVLKPDLVLLDVYLPDGTGLDILQWVRGRNACCDVILITAARDVETLQQAMRGGVVDYLLKPVMFPRLEAALKKYQARQ--
+----TRVLICDDSKMARKQLAKVLPDWNVE-IEFAENGQDALEQIAANAFDVLFLDLNMPIKDGYETLEALQGFSQAPVVIVVSGDVQPKAIERVKAMGAAAFHKKPAATEDIRTLL---------
+----TRVLICDDSKIARKQLARILPDWDVE-VGFAEDGQEALDILSTADFDILFLDLNMPVKDGYETLEALKSFNKSPAVIVVSGDVQPKAIQRVKNLGAVAFHKKPASAEDLRSLL---------
+----TRVLIAEDHEIENIGVINTLKELNITDYAFTNYCDDAYKLIAEHPFDVLVTDLGFISTSGQELIRDARALQPNLKIIAFSIEKRAAVIDELFEYGVDGFVSKGNDGRELRSTLLKVMA----
+----TRVLIAEDDEDLRTNMVDILELEGFD-VIAVPSAEEAILACQTHSFDIALMDLVMSGMTGVEAISNLRQENPFMAVVIVTAYATVDTAVDAMKKGADSVLTKPFKSVDLVMTIRRSIAEK--
+----TRVLIADDSEFMRNLLREILEGE-FEIVGEAENGVEAVNMYEEHGPDLVMMDIVMPIRDGIEATTEILETNPEATVIMCTSVGQEEKMKAAIKAGAEGYITKPFQKPNVLDAIGS-------
+----TRVLIADDQEMVRAGFALILAQPGIDVVAQCADGVEALEAARRLRPDVALLDVRMPRLNGLEVTRRLAGVLDPVRVVVVTTFDLDEYVHAALRAGACGFLLKDAGPTLLVEAVRAAA-----
+----TRVLIADDQALLRGSFRVLVDSAGLEVVGEASDGAEAVALTRLERPDVVLMDVRMPEMDGIEATRRICAE-TDVRVLMLTTFDLDEYVYSALRAGASGFLLKDTRPADLLAAIEVVA-----
+----TRVLIADDNAIFREVIKRHVVLFGFE-TVEAADGAAAVALAEAGRPDLILLDLMMPGMDGIEAIRRIRAAMRDVPIVFLSAETDRRKWAEALSAGANDFISKPYHRQELEARLSLHL-----
+----TRVLIADDHAVVRDGLKHILERAGFDVVGEAADGSQVLKLVRDCAPQVLLLDLSMPGRSGLELIRLLRDEQQALRILVLTMHAEQQYIVRAFQAGAAGYLTKESAATELVSAITQVA-----
+----TRVLIADDHAVVRDGLKHILERAGFDVVGEAADGSQVLKLVRDCAPQVLLLDLSMPGRSGLELIRLLRDEQPALRILVLTMHAEQQYIVRAFQAGAAGYLTKESAATELVSAITQVA-----
+----TRVLIADDHALVRDGLRHILQTSGFEVAGEASDGSSTIALVRSRPAEVLVLDLSMPGRNGVELIRQIKDEMPALRILVLTMHAEQQYAVRAFKAGASGYLTKESASAELVSAVSKVA-----
+----TRVLIADDHALVRDGLRHILQASGFEVTGEANDSVSTVALIRERAADVLVLDLSMPGRNGVELIKQIREEKPALRILVLTMHAEQQYAVRAFKAGASGYLTKESASAELVAAVTKVA-----
+----TRVLIADDHALVRDGLRHILKASGFEVVGEADDSASTVALIRERAADVLVLDLSMPGRNGVELIKQIKEEKPTLRILVLTMHAEQQYAVRAFKAGASGYLTKESASAELVAAVTKVA-----
+----TRVLIADDHALVRDGLRHILKASGFEVIGEADDSASTVALIRERPADVLVLDLSMPGRNGVELIKQIKEEKPTLRILVLTMHAEQQYAVRAFKAGASGYLTKESASAELVAAVTKVA-----
+----TRVLIADDDSVVRDVVRRYLERDGLE-VAIARDGTEALRLLGTERIDVAVLDVMMPGPDGVTLCRTLRQREHTVPVILLTALGEEDDRIAGLEAGADDYLTKPFSPRELALRVRSVLRRS--
+----TRVLIADDDSVVRDVVRRYLERDGLE-VAIARDGTEALRLLGTERIDVAVLDVMMPGPDGMTLCRTLRQREHTVPVILLTALGEEDDRIAGLEAGADDYLTKPFSPRELALRVRSVLRRS--
+----TRVLCIEDNLSSQALIETLLQRPGVQ-LLSSMQGQLGLDLARQHLPRVILLDINLPDMTGIDVLKRLRALTAAIAVLMITADASTAARRAMQQAGATAILTKPIHVPTFLAFLDQHL-----
+----TRVLCIDNEVAIREGMRVLLAGWGCE-VEAYGSASEAIPDLGRRAPDIALVDYHLDEGTGLDAVTALRRFGPELPVILVTADRSPGLREQAAGMEV-DILTKPLKPASLRAAMG--------
+--TRVKCLLVDDLEENLLALGGLLRRDDVE-VLQARSGGEALEMLLLHDVALAFVDVQMPEMDGFELAELMRGRTRHVPIIFVTAGVRDHRLFKGYDAGAVDFLYKPLEPHVLRNKAEV-------
+----TRVIVVDDSAFFRSSITKMLTDSEIEVIGVAKDGIEGLEKIKNLKPDVVTMDIEMPKLDGISTLKIIMDE-MPLPVIMVSSLTKEEATLKALEFGAVDFIPK--------------------
+----TRVIVVDDEPLALVSMEKHLNEFNIEVIRTFTTAKDVLKEGPNLDFQVAFLDVEMPGMSGLEIAQLIKTWDKNICIIFVTAYR--DYAVQAFDVQSLDYLLKPVSKSRLEMTINRIQ-----
+----TRVIIVDDQAMVRAGFAALLAQSDIDVVGEAPDGAQGVELSRRTHPDVVLMDVWMPEMDGLEAARRLLEVTHRPRVLMLTTFDVDDYVYEALRAGASGFLLKNAPPADLIAAVRVVA-----
+----TRVIIVDDQAMVRAGFAALLAQSDIDVVGEAPDGAQGVELSRRTHPDVVLMDVRMPEMDGLEAARRLLSVTHRPRVLMLTTFDVDDYVYEALRAGASGFLLKDAPPADLIAAVRVVA-----
+----TRVIIVDDQAMVRAGFAALLAQSDIDVVGEAPDGAQGVELSRRTHPDVVLMDVRMPEMDGLEAARRLLEVTHRPRVLMLTTFDVDDYVYEALRAGASGFLLKDAPPADLIAAVRVVA-----
+----TRVIIVDDQAMVRAGFAALLAQSDIDVVGEAPDGAQGVELSRRTHPDVVLMDVRMPEMDGLEAARLLLAVTHRPRVLMLTTFDVDDYVYEALRAGASGFLLKDAPPADLIAAVRVVA-----
+----TRVIIVDDQAMVRAGFAALLAQSDIDVVGEAPDGAKGVELSRRTRPDVVLMDVRMPEMDGLEAARRLLDVTHRPRVLMLTTFDVDDYVYEALRAGASGFLLKDAPPADLIAAVRVVA-----
+----TRVIIAEDQKLLRESFKNIIENSDIKVVACATNGNEAYDLCKEYMPDVVLMDLSMPICNGTEATKLIKAELPSVKVLVLTASNDKSDVTDAISNGADGYILKDISTEELILSIKS-------
+----TRVFVVDDHEVIRRGIAALVNESDLELIGEASTVAESLALVPQANPDVAVLDVRLPDGNGVELCRELQSRRPGLRCLMLTSFDDHDALMDAIIAGAAGFVLKGVVSEELVNAIRTA------
+----TRVFLVEDHPLMRQGLVAALGQVEIAILGEAESGEEALAALAERTPDVVVMDIGLPGLSGIETTRRLKAARPDLRILMFTVHQLEGEIFGAFSSGADGYCLKDSELDSLILGIQAV------
+----TRVFLVDDHEIVRRGLVDLLGSVDLEVVGEAASVGEAMARIPGSGADVAVLDVRLPDGNGVELCRDLRTALPELQCLMLTSYSDDEALFDAIMAGASGFVLKQILGTDLVAAVRTV------
+----TRVFLVDDHEIVRRGLVDLLGSVDLDVVGEAASVGEAMARIPGSGADVAVLDVRLPDGNGVELCRDLRAALPELRCLMLTSYSDDEALFDAIMAGASGFVLKQILGTDLVAAVRTV------
+----TRVFLVDDHEIVRRGLVDLLGSADLTVVGEAASVGEAMARIPSSGADVAVLDVRLPDGNGVELCRDLRTVLPDLRCLMLTSFADDEALFDAVMAGASGFVLKQILGTDLISAVRTV------
+----TRVFLIEDNPEMLDATQMLLQRWGCE-VLPLESQDPTLLDT-QCECDVIIADYDLGKISGIEYIQAIRNKAEQIPALLITGHDV-TNISIFVKDLNIEIVSKPIKPVELRSVLTDIVRKT--
+----TRVFIVEDHAFTRDGLRVAVGREDLQVVGEARSAEEGIEQLAHTSADVVLMDIGLPGMDGIEATKLVKER-FGVRVVVLTVHQLEAEVLAAMTAGADAYCLKSTDPASLLLAIRAA------
+----TRVCLVDDQTLVRQGIRSLLADDGIEVVAEASDGKQAVEQIPQIQPDVVLMDMRMPVMSGLEALQMLSRNGALPPTIILTTFDDDQLVLAGLKAGAKGYLLKDVSLEQLVGAIRTVA-----
+----TRVAVADDHPIVQRAVAECLNALGFQVVATATSGGSLLTELTHHEVDLIVTDYNMQDKDGLRLVSHLLRVHEGTPVVVFTMLTNPGVLTQLCRMGVAGLVGKDEELTELGQVCLRVVR----
+----TRVALIDDHESVRLGLEAALAQTAAT--EVVFSGANVAAYLDQSPADVVVLDLTLG--DGTTVSENVDRVRDGSSVIIHSVADRPAAVREALAAGAAGIVSKSSPTHEVLGAIGTVAR----
+----TRVALADDHAIVLEGLKQVLSGVGNLVAGEAADGAQLLGLLERVPTDLLVMDLGMPGVDGLAFVERLRTRHPALRILVLTGSAGAGMAHAAIDAGANGYLVKSGDISELVPALMAL------
+---TRTVVVYSDDATVRERVRLALGRRELR-YIECATQYAVLEAADHENVDLFILDGEAVPAGGMGLCRQLKDEYRCPPVIVLIARRDDGW--LATWSRADATVLHPVDGVRLTPVVVDLLRRR--
+---TRTVLIIEDEAAIAETICYALSTDGFQ-PHWRATGREGIACAEALRPPLVLLDIGLPDSNGFEVFRSLQSRFETPPVIFLTARSEEVDRVVGLELGADDYIGKPFSPRELCARVRAVLRRS--
+--TRTRVMIVDDHEIVRRGIAEIVDRAGLEVVAEAGSVQDALRRAELVRPDVILVDLQLPDGTGIDIMDSLGRTHPEVLPIVLTSFDDDEALAESLDKGARAYVLKTVRGAEITDVIKAVA-----
+----TRTLLVDDDRSCVVLMMRILEILGQREIDVASDGQAAYAMMRTKEYGLVVSDLHMKPWSGLDLLRRVRALLRKTPFVLTTMDTEIANVGDARDCGADAYILKPYTPAMLREKIEPLLRRQE-
+---TRTILVADDDRAIRTVLSQALGRAGYT-VRATSSAATLWRWVEEGAGDLVITDVVMPDENGLDLVPRIKRVRPELRVVVMSAQSTFMTAVKAAQRGAFEYLPKPFDLKELLAVVARALT----
+--TRTDVLIIEDEPIIAMDLETIVRDLGHSVSGVAVTRDEAVAQAHAHRPGLVLADIQLADSSGIDAVKDILAE-FSVPVIFITAFP--ERLLTGERPEPTFLITKPFQRSTVKAAISQAL-----
+---TRSVVVADDHPIVLRAVTDYVNSLGFRVVASVSSGDALLSAMREQEVNLVVTDFTMHDKDGLRLISHLMRAYERTPIIVFTMLTNSGVISQLCRMGVAGLVGKEEEIAELGRVCLNVAR----
+---TRSVLLYSDDAPVRAQVRQALGSHDLE-WHEVATYDALVERVIPGRFDLLILDGEARKAGGMGVARELKNQYNCPPILVLTGRA--QDAWLASWSLADAVVPRPLDALTLSDTVEGLLE----
+---TRSVLLVDDSAFFRNMLGPVLKAAGYK-VRVATSAVEGLAVLRSAQFDVILTDIEMPEMNGFEFAEAIRAKMSNLPVIALSSLVSPGAIERGRQAGLTDYIAK-FDRPGLIAALKE-------
+---TRSVLLVDDSAFFRNMLAPVLKAAGYQ-VRLATNAQEGLVALRSQEFDAILTDIEMPDMNGFEFAETVRSRLSDTPIIALSSMISPAAIERGRQAGFHDYVAK-FDRPGLIAALKEQT-----
+---TRSVLIVEDEEIIRTSLLEFLTDEGYQ-AMAAPNVATALKLAREREFQVAVCDVQLPDGDGLALLRKLQQITPGVSGLIITAYATVENAVEAFKSGAFDYLVKPVIFDDLANKLARLFQ----
+---TRSVLIADDEPLARERIRRLVEAVGYRVCGEAADGDSCLKQVAELEPDILLLDIRMPGMDGMEAASRLSQLANPPALIFCTAYD--HYAIQAFDVQAIAYLLKPVRKEALAEALARA------
+--TRSRLCLIEDDEIIGESLTDRFRLEGFD-VDWCRTGVEARAALAAHRHAVVISDIRLPDCNGGELFLDLLASVPMLPFLFMTAFGSIDRAVELIKAGAADYITKPFDPDALIAKVHALAE----
+-------------------TRSKLESMDYI-VTTFTDETEALSAVVKNRFHVAIVEVNTRENESFKFLEGAKD---VLPTIMISTDHCITTTMKCIALGAVEFLQKPLSPEKLKNIWQHVVHKA--
+--TRSKILIVEDNEELRGLLARLFSKI-YT-VYEAQDGEEGFEKTKEVQPDIVLSDIMMPKMSGIEMCRKIKSETSHIPVILLTAQTAEEYTMQGLKMGADDYVTKPFNVKHLFMRCNNLVNS---
+--TRSKIIIVEDNEELRGLLARLFSRI-YT-VYEAQDGEEGFEKTKEVQPDIVLSDIMMPKMSGIEMCRKIKSETSHIPVILLTAQTAEEYTMQGLKMGADDYVTKPFNVKHLFMRCNNLVNS---
+--TRSKIIIVEDNEELRGLLARLFSKI-YT-VYEAQDGEEGFEKTKEVQPDIVLSDIMMPKMSGIEMCRKIKSETSHIPVILLTAQTAEEYTMQGLKMGADDYVTKPFNVKHLFMRCNNLVNS---
+-------------------TRSELESMDYI-VTTFTDETEALSAVVKNPFHIAIVEVNMSESESFKFLEAAKDV---LPTIMISTDHCITTTMKCIALGAVEFLQKPLSPEKLKNIWQHVVHKA--
+---TRRVVVAEDEAIIRLDIVEMLTEAGYDVVGQAGDGEQAVALAEEHKPDLVVMDIKMPILDGISAAERIAKA-RIAPVVLLTAFSQAELVERARDAGAMAYVVKPFTSADLLPAVEIAVSRH--
+---TRRVVVADDHPIVLRAVTDYVNSAGFHVVASVSSGDALLSAMREQEANLVVTDFTMHDKDGLRLISHLMRAYERTPIIVFTMLTNSGVISQLCRMGVAGLVGKEEEIAELGRVCLSVAR----
+---TRRVLVVEDEPVINQAVSDRLTAEGYD-VVRAWDGPGAVSCFEETSPDLVVLDVMLPGYDGLEVCRRIQAV-RPVPVLMLTARVDEADVLVGLGVGADDYLTKPFRARELVARVNALLRRV--
+---TRRVLVVEDDRKMADALVSGIKAAGYD-VSVARTGEEGFFLVHKLFPHLLVLDLHLPQRNGLEILQQIRAQALDIRILILTSNNTPEDRVTGLNAGADDYLGKPFSFPELLARIGSLLRRM--
+---TRRVLLVEDDAHIADLLTLHLRDEGLE-VMHCARGDDGLRQLERGGWDALVLDIMLPGVDGLEICRRARAMARYTPIIIISARSSEVQRILGLEIGADDYLAKPFSVLELVARVKALLRRV--
+---TRRVLLVEDDAHIADLLTLHLRDEGLE-VMHCARGDDGLRQLERGGWDALVLDIMLPGVDGLEICRRARAMARYTPIIIISARSS--------------------------------------
+--TRRTVLVVEDNDANFALMQRLLESTGLWTIVRATRVTEAEAELARGKPAAMLLDLDLPDTDGLTLARRVKAALRDIPIVVVSASVMKQERDRAEAAGCEYFVEKPFDIDRLRSVVAEA------
+--TRRTVLVVDDTVDNLTLLSDLLKD-TYR-VKVANSGEKALRILSSSPPDLVLLDIMMPGMDGYTVLRRLKELTADVPVIFLTALSEEDDERIGLELGAVDYITKPISPSIMLARVRTHLQ----
+--TRRRVVLADDSPTTRALEQSILESAGYE-VVACVDGADAWERLQSGGADALVLDVEMPRMDGFALTEAVRARFSRLPVVLVTARGKPEDKARGLQAGASAYLVKSFDPTSLLETLRRLL-----
+-TRRLRVFLVDDHAMFRAGVRAELGAH-VDVVGEASTVGEAVSRIAATEPDVVLLDVHMPEGGGRAVLEAIRRTYPHVRFLALSVSDAAEDVIGLIRAGARGYVTKTISPDELAAAVRRVAE----
+---TRRLLVVEDDDSIRETVGEALRAEGFE-VHTCADGASALTLITADPVDLIVLDLMLPGLGGLDLCRELRRLNNTTPILVISARDSETDRVLGLEVGADDYLVKPFGLRELVARCRALLRRSS-
+---TRRLLLAEDAPENRLLFKAYLKGTPYL-LDLAVNGEEAVVKFKQGHYDLVLLDIQMPGMDGYAAARAMRAGREAIPIVALTAHAFRDDIRKSREAGCDGHMVKPIKMDDFLRTIRTYI-----
+---TRRILLVEDDEAVADSLAMLLQIQGHE-VRIIHRGKQTLEAVQSFQPEVVLLDIGLPDRDGYGVARQLRQELENLPLVALTGYGQSEDIQQAKAAGFNRHLLKPATVETLQKLLG--------
+---TRRILLVDDEPSLQKMLTHALEREGFQ-VQAVGDGEAALEAFNTFEPHLIILDIMLPKLDGTEVCRRIRAQ-SDVPILMLTAKDDEIDRVVGLELGADDYVTKPFAVRELVARVRAIMRRAQ-
+---TRRILLIDDDVELAQMLREYLEPGHCQ-LTLAHSGAHGLALLAQDDYDLVLLDLMLPDGNGLDLLKQYRQR-SRRPVIMFTAHGGETDRVLGLEFGADDYLAKPFSPRELKARISAVLRRF--
+---TRRILLIDDDVDLALMLREYLEPTHIE-LTLAHNSAQGLPLAMQECFDLVLLDLMLPDGNGLDLLRHLRRH-SRRPVIMFTAHGGETDRVLGLELGADDYLTKPFGPRELKARIGAVLRRF--
+---TRRIALVDDHRMFSDGFSALLMQLGHI-VDVFDDPVDFLKSFQSDSYDLIILDLVMRTMNGLALLAAIRERKSRCPVLMLSGIGADPPLAEMKKLGARGFVHKSADTETLLAAVDGILA----
+---TRRAVVVDDEQALALLVAGYLERDGFE-VQLCFDGAQAVELIRQVDPDVVVLDLGLPGLDGIEVCRGLRT-FSDCYVLMLTARAEGVDTLIGLSVGADDYMTKPLSPRELMARIEVLLRR---
+-TRQLHVLVVDDDRYVRPVLVRLLQRHGFR-VTNVADGLTALTIIEQARPDVVLLDVKMPGIDGTEVLRRIKELTAMTRVIILTANDLESLQSQVLRLGADGYLEKPITYERLISMVM--------
+--TRQKILVVDDESANLHLLEQSLTDLA-E-IICSTGGQDALDKAEQHQPAIILLDIEMPQMNGFEMCKRLKNKTCNSAVIFVTAHSESSFEYKSLSSGGIDFIHKPIDLATCRLRVKNH------
+--TRQKILIIDDEAALRETLEALLSLEGYE-VETAIHGEAGLEKIDRNSYDLVLLDLALPGKNGIEILGLIRDRNADLPVIMITAFGTVDNVMDAMRAGAQNFIQKPWDNEKLLADIRSAIARHQ-
+--TRPTVLFVDDESMLLSSLQRLLRREPFT-ILLAVSAREAMEIMARTPVDVLVVDLQMPDIDGYELLSRVEVLHPQTVCLVMSAVADKEKVEEVVRHHVFKFIAKPIHPDVLKRVIRDSV-----
+--TRPTVLCVDDEIRSLETLERTLDE-EFN-VITATDADQAMALLEQHNVQAILCDQRMPGRTGVEFLTDVRKRWPQTARLILSGYTDSEDIIKGLEAGILQYITKPWHPDNLLLIMRGACR----
+--TRPTLLVVEDDPGLLGQLRWCFED--FE-VATATTRDEAIAQLRRSEPSVVTLDLGLPASEGIATLEQILTLAPDTKVIVVTGNSDRENAVKAVGLGAYDFYQKPVDADLLNLIVKRAQ-----
+--TRPTILIVEDIVFIRMMTEDYFANAGFR-TLSARTTAEAIVLLETDPIRYLFADIHLPGEDGQKLAATARKRWPPVKIILTSADM-PADQVRLPVRGL--FVPKPYSLDRVRQAFE--------
+--TRPSVLLVDDNDVNLKLLVAFMKKAKFP-YLTASNGLEALEVYKAHQVPVVLMDISMPVMDGLESSREIRSSFKPTTIIALSGLGSAPVRQEAFNSGVDLFLSKPIRFQELVKQIDDLMR----
+--TRPRILVVEDEITIREFCRLLLRR-EYD-VAVAEHGQAAIELLNIQPFDLVVTDLQMPHLDGLALVQYLRTHCLETDVIVMTAHATVETAREALKLGALDYISKPVDAEQLQKTIRTALE----
+--TRPRILLVDDNAVNRKVVKLQLKKLGYD-CDTATNGFEGFEMQKKDNYELIFMDLNMPLCDGSMASKLIRSHKSRANIVGLSATYLHGSKDYCVSMGMDDFVVKPLKLQPLGELVKKYLE----
+--TRPKLLIVEDDPGLQRQLRWAYDA--YR-VFIAGDREEAIDMLRAEAPDVVTLDLGLPTSEGFATLADMLRIKPDTKIIVASGHGERESALEAIAGGAYDFYQKPVDIHELGLIVRRAFH----
+--TRPKILAVDDEDFNLDILGEILDEAGYQ-PVLAVDGREALALLELHPIEVIVLDRMMPNMDGMACLAALKSRWRDLPVIMQTAAASHDQVRQGIEAGVFYYLTKPYAADILLSLVRSALDD---
+--TRPDIIIVDDNPHNLRVLSTILKKEGYE-IRPATGGQTALAAIDAKPPELILLDIMMPAMNGYEVCECLKKNTRNIPVIFITALDDVKDKIKAFAMGCTDYISKPFQEEEILARVKTQI-----
+--TRNRILIVDDEDNVRRMLTTALTLQGHE-THAASHGAEALQRFADAPPDVVLMDIRMPTMNGIDALKVMRARQPRTPVILMTAYAEVETAVEALRSGAFDYVIKPFDLDELNLLIQRALQL---
+---TRNILVADSHPVARLGVSTLLEQFDID-IYIASSFEELQSMLFVVKYDLLIMEIELPNGNWVAIIDQILSVQKDLKIIILSKQDNKFLASASFMKKTFAYVSKDQSIEYIRNVIQTVLS----
+---TRNILIADSHPVARLGVSTLLEQFDID-IYIASNFEELQSMLLVVKYDLLIMEIELPNGNWVAIVDQILSVQKDLKIIILSKQDNKFLASASFMKKTFAYVCKDQSIEYIRNVIQTVLS----
+--TRNHVLVVEDDADIAGLVVHEASQLGYD-VTTADTVDGAKRRTSEQMPDIVILDRMLAGSEGLDYLAWLNAEGPRPGILVTSRLTSVSDHVAGLEAGADDYIDKPFHPEELRARLRAVARRAS-
+---TRMVLIVDDEPSMRTALSETVRRLGYQ-VRGAIDGVDAIEQIERIKPWLVVTDLKMPRLTGLELVKAIKQKSPQTFIVLMTAYGTVETAVEAMKYGANDYLLKPFSTDLLERVILNLQ-----
+--TRMKILVAEDFELNVKLMKRIAKKHHLT-MDFASNGREVLDKLNDQSYDLVLMDIQMPVLDGIEATKLIRRRFAHIPIYALTADSDLVQQEVCTDAGMNGYITKPIKADKLFTLLAEL------
+--TRMKILLADDHHEFAELLSEFISQPDMEVCGIAHNGTEVLNLVRETRPDVLILDIIMPVLDGLGALERLSETDHPPKVIMLTAFGQESVTRRAVELGVSYFILKPFDMPVLAERIRQVMF----
+--TRMKILLADDHHEFAELLSEFISQPDMEVCGIAHNGTEVLNLVRETRPDVLILDIIMPVLDGLGALERLSETDHPPKVIMLTAFGQESVTRRAAELGVSYFILKPFDMPVLAERIRQVMF----
+--TRMKILIVEDDLEAAAYLAKAFREAGIV-SDHASDGESGLFMASENAYDALVVDRMLPRRDGLSLISELRRRGIHTPVLILSALGQVDDRVTGLRAGGDDYLPKPYAFSELLARVEVLGRRK--
+--TRMKILIVEDDLEAAAYLAKAFREAGIV-CDHASDGESGLFMASENAYDVLVVDRMLPRRDGLSLITELRRKDIHTPVLILSALGQVDDRVTGLRAGGDDYLPKPYAFSELLARVEVLGRRK--
+--TRMKILIVEDDLEAAAYLAKAFREAGIV-CDHASDGEAGLFMASENAYDVLVVDRMLPRRDGLSLITELRRKDIHTPVLILSALGQVDDRVTGLRAGGDDYLPKPYAFSELLARVEVLGRRK--
+--TRLVILIVEDNKDILDYIAESFTDL-YE-VKTALNGKEGMEIALECIPDIIVSDIMMPVMDGITLCKQLKNRTSHIPIILLTAKDTLSDKEEGYQSGADSYLTKPFSASLLHSRINNLLAQR--
+----TRLVIADDESIIRMNLKETLVSLGYLVVGEAGDGVSVINLARELRPDLVLMDIKMPKLDGIQAARILTEE-KIAPVLLLTAYSDRDLVERAKEAGVVNYIVKPFREAELLPAIEIAIARY--
+--TRLRVLLVTDTDKPIGELGDALARLGYEMLNDVATPARLPAAVEEQRPDVVIIDTDSPSRDTLEQLAVMHAT-APRPVLMFSHDADQELIRAAVGAGVSAYLVEGLSAERLAPILEVALARF--
+--TRLRVLLVTDTDKPIGELGDALARLGYEMLNDVATPARLPAAVEEQRPDVVIIDTDSPSRDTLEQLAVMHAT-APRPVLMFSHDADQALIHAAVGAGVSAYLVEGLSAERLAPILEVALARF--
+--TRLRVLLIEDDDGDALLVEEMLADTSVP--YTLERVQTLTAALDGLTADCVVLDLQLPDAMGLSGLTKLGQHAPGVAVVVLTGQHDQATGVAAVAAGAQDYLVKDVDGPLLVKALRFARE----
+--TRLRVILAEDDVLLREGVASLLTRSGFDVLEQAGDATTLLDLVRERAPDLVMVDIRMPTTEGLDAARAIRDEFPEVGILVLSAHADVEHAMELLASGGIGYLLKSTDVDDFIDTLQRIA-----
+--TRLRVFLADDHPVVLSGMKALVADPAIEIVGEASDGPNALRRAIELKPDVAVLDLSMPGLNGIEVARKFLAACPECRVLVLTVHEDGAYLRQLLDLGVSGYVLKRSATEELIRGIHA-------
+--TRLRLLLVEDHAATLNAVSRLLRRDGHT-IVAVGTAAEAVKAAEVGEFDCVVSDIGLPDGSGLELMKTLRAR-HGLRGIALSGYGREADLIQAREAGCVAHLTKPVAIAELRATIASI------
+--TRLRILVIDDEPPIRKLLRMGLSSQGYE-VAEAGTGRAARQALAQAAVDLVILDLGLPDIGGHDLLRLIREGFPSLPVIVLSSRGDETGKVEALDLGADDYVTKPFGMNELLARMRTALRHQ--
+--TRLRALVVDDSAMMRRLVRETLSDPAFAVVGEAGDGRAALALMAELRPDLTMLDIEMPVLDGIGTLREWALSG-HGAVVIVSSAARPELAALARRLGASAVVGKPS------------------
+--TRLPVLVIDDHPIVLQGCRRVLEDSGVETIAEATTVVGGYRIFHRLRPPVVICDLTFQGMAGLGLIRRIRAVAPETRILVFSMHNDPVIVARALEAGALGYVLKDHASAELFEAFAKV------
+--TRLPILAVEDHPETLFIYENHLQHSIYQ-LIATRTLTQARQVLQKVRPAAIMLDIMLEGQNGWTFLRELKGTTRSIPVIVITIID---NEKQALALGADGFLIKPVDRLPLLKKLNTHR-----
+--TRLNVVVVEDSLAMQKLYRMTIESWQLPDVKFVSNGCEGIIYVSQHTPDLLITDLKMPEMDGFAMLKSLRDDFSKMAIVVVTGMQAQEIEEKGLPKGVRLYGKSPVPFWEMRELMQGLIDRK--
+----TRLMIVDDEERFLKTTKGLMEKRKCI-VSTALSGIEALEILAKQEMDVVILDVKMPGMDGVEVLRRIKQTHPLVEVIMLTGHSTTESAVEGMKLGAFDYLLKPCDINILFSKVMEAVDKK--
+----TRLMIIEDEPLIAMDIEQMVESLGHEVVGIARTKDEALALYEKEKPRMVLADIQLAGSSGIDAVNEILHD-NTIPVIFITAFP--ERLLTGERPEPTFLVTKPFNSDMVKALISQAL-----
+----TRLMIIEDEPLIAMDIEQMVESLGHEVVGIARTKDEALALYEKEKPRMVLADIQLAGSSGIDAVNEILHD-NTIPVIFITAFP--ERLLTGERPEPTFLVTKPFNPDMVKALISQAL-----
+----TRLLVVEDEESFSEALSFMLEREGFD-VAVAADGHAALSDFERHGADLVLLDVMLPGLSGTEVCRALRQK-SSVPVIMLTARDSEIDKVLGLELGADDYVTKPFSARELVARIRAVLRRRG-
+----TRLLVVEDEESFSDALSFMLEREGFE-VGVVADGPSALAEFDRRGADLVLLDLMLPGLSGTEVCRTLRTR-STVPIIMLTARDSEIDKVLGLELGADDYVTKPFSARELVARIRAVLRRR--
+----TRLLVVEDEESFSDALSFMLEREGFE-VGVVADGPSALAEFDRRGADLVLLDLMLPGLSGTEVCRTLRTR-SSVPIIMLTARDSEIDKVLGLELGADDYVTKPFSARELVARIRAVLRRR--
+----TRLLVVEDEESFSDALSFMLEREGFE-VAVVGDGPSALAEFDRRGADLILLDLMLPGLSGTEVCRTLRAR-STVPVIMLTARDSEIDKVVGLELGADDYVTKPFSARELVARIRAVLRRR--
+----TRLLVVEDEESFSDALSFMLEREGFD-VAVAADGLAALTEFERHGADLVLLDLMLPGLSGTEVCRALRQR-STVPVIMLTARDSEIDKVVGLELGADDYVTKPFSARELVARIRAVLRRRG-
+----TRLLVVEDDPDLGLALRVLLARRGYE-VSVAEDGREGLRLLFAERPALMILDLLLPELDGWQVLDRTRDM-SDLPVLVLSGLGDVDDRVRGLRSGADDYLVKPFAHPELLARVDALLRRS--
+----TRLLVVEDDDTIRETIAEALSSEGFE-VDAVGSGSTALERFKGSPCDLVLLDLMLPGVSGLDVCRYMRRRGFSTPIIVVSARDSETDRVVGLEIGADDYLVKPFGMRELVARCRALLRRS--
+----TRLLVVDDNDTCRKVLLQQCNAWGMN-VSSVPSGKEALALLRTRAFDVVLLDQDMPGMSGMQLAAKIKELNNDILIIMLTGISHAPSKIIARNAGIKRILAKPVAGYTLKATLADEL-----
+----TRLLVVDDNAENRNMLRMLLTSWGVR-VSEVSCASTAIERLRQDPFRIAIIDMEMPEIDGLMLGRSIKDALADTALLMMNSIGRRPDNEKLRRSGFFSFLVKPVRQSELYNTVSEVLF----
+----TRLLVVDDEQDIRYLFQCELEEEGYH-VDAAGSAAEAERFLRENRYDLVVLDIQIGGDNGLAMLQDIIGRQKDLPVILCTAFS--CYKEDFSSWLADGYVVKSSDLSELKSEIQRVLTKKG-
+----TRLLVVDDEPAILDVLATSLRFLGYE-VAEATTGRAALTAAREGGFHLVLLDVVLPDLDGFAVVRRLREGGGRVPVVFLTARESPEDIVAGLDLGADDYITKPFRLAEVAARVRAVLRRR--
+----TRLLVVDDDTTHRGMLQTLLADWGYR-TECAGDGETAVTLCRETPFDLILMDLRMGVMSGIGALREIRAYNPAIPILIMTAYSNVESAVDAIRSGAYDYLTKPLDFEELRLTLERALDHA--
+----TRLLVVDANPTRREQLARTLQTIGIL-TLLAESLAEARPLMNNRTAGLILDETAISTAEASQAINELRHLDRQLPAIFMSALKSDLGSDLGAALDDVVILWKPVKQSALYQALRSI------
+----TRLLVIDDDRKLCRLIKDYLEPMGYE-IALAHTGPEGAEKAVSETFAAVILDVMLPGMDGFEVLKQIRRA-SNVPVLMLTARGDESDRIVGLEIGADDYLPKTFSTRELLARLRAVTRRS--
+----TRLLLVEDDSAIAEPLSRALDREGYT-VTRASRGMDALGIAAGESIDLVILDLGLPDLDGLEVARRLRKGGLECPILILTARADEVDAVVGLDAGADDYVTKPFRLGELQARIRALMRRS--
+----TRLLLVEDDPISRAFFHITLESLPAQ-IDLADSVATALAHAGIRNHDLWLIDANLPDGSGTELLQQLQRQCPGAQGLAHTADASDTVREQLLRGGFAEVLLKPLSAEHLLQRVRWLLAR---
+----TRLLLVEDDPDLGRTVTQALEEHGFQ-VVWATSQEEAWEALWDVPFQALVLDVRLPEEAGFHLARTLREAGFTQPILFLTAKDALDDRLHGLELG-EDYLTKPFALSELVARIRALLRRG--
+----TRLLLVEDDDALVRTLELTLGVHGFD-VHATGLGAQALVLARTFQPEIAIVDLGLPDLDGLEVVRALRA-WSDVPVLVLSARDAQHDKVGALDAGADDYVTKPFGMDELLARLRAALRRV--
+----TRLLLVEDDANLCYIIRGGLEDMGYE-IQTAADGEEGLRIWKTWKPDVIVSDIEMPVMDGYEMVRRIRETDERTPILFTSGRVSPKDVVKGYELGVNNYIKKPFLPEELHAHVTALLR----
+----TRLLLVDDQPMLRIGFRMVFEQPDIEVVGEAGDGERAVAMTRALSPDVVLMDVRMPVVDGIQATRRIVETGSAARVLVLTTFDLDEYVFAALRAGASGFLLKDVPPEDLLGGIRAVA-----
+----TRLLLVDDDEIFCQVLAKALGRRGFD-VLTAHSIEQALRQLDETGPDYAVVDLSMPGGSGLVLVEQLHARSAKMRIVVLTGYASIATAVEAIKLGAIHYLSKPANADEIVQA----------
+----TRLLLIDDDTALCELLSEYLALEGYA-VEAVHDGEAGLAAALSGRYRLALLDVTLPRLNGFEVLKRIRQE-SSLPVLMLTARGDDFDRVVGLEIGADDYLPKPFNHRELVARIKAILRRT--
+----TRLLIVEDNRDILANLADYLTLKGYE-VDCAQDGLTGLHLAATHHFDLIVLDVMLPGMDGFTLCKRLREERSDTPIIMLTARDALDDRLIGFSAGADDYLTKPFALSELVARIEAVLKRS--
+----TRLLIVEDEPLLRAVQSEMFTSMGFI-VDAAADAQSAYKSWIQYQHPMIITDCRLDNSDGFELVLHLRKNSESVLIIGQSASLKDDDYMRAKEVGMNHIMRKPVSVKTWHSLI---------
+----TRLLIVDDSALMRRVLGDVFQEPGFE-VAFARDGVEALAQVHAFRPDVITLDVQMPRMDGLSCLDRIMVE-RPCPVVMVSSLTAEDATLEALELGAVDFVAKP-------------------
+----TRLLIVDDNDTCRKVLVQQCSGWGLD-VSAVASGKEALALLRTKAFDVVLLDQDMPGMTGMQLASKIKELNHDILLIMLTGMSSAPSKIIARNAGIKRILAKPVAGYTLKTTLADEL-----
+----TRLLIVDDEALVRAGLKMILESADLQVVAEAEDGADAAAMVREHRPDVVLMDIRMPRLDGLAATREIQALPEPPKVVVLTTFDLDDYVFRALQAGASGFLLKDTPPRELVQAVRVVA-----
+----TRLLIIEDNPELVANLYGFFEPLGYV-LDDARDGATGLRMATQHDYDAILLDLMLPRLDGMALCRKLREEQNPVPVLMLTARDPVDDRVQGLAAGADDYLVKPFSLRELDARIQALVRRA--
+----TRLLIIEDNPELVANLYEFFEPLGYV-LDDARDGATGLRMATQNDYDAILLDLMLPRLDGMTLCRKLRQEQNPVPVLMLTARDPIDDRVQGLALGADDYLVKPFSLKELDARIKALVRRS--
+----TRLLIIEDNPELVANLYAFFEPLGYV-LDDARDGASGLRRATQDDYDAILLDLMLPRLDGMTLCQKLRQEQNPVPILMLTARDPVEDRVQGLALGADDYLVKPFSLTELDARIKALVRRA--
+----TRLLICDDHAMFRQGLRSILEEEGFRVIGEAATGREAVRYALETHPDVILMDIQMPELDGVAATKTILEEFPDAKVIILTMYRQDRYVFEAVKAGARGYLLKDAGADDLISAIRRV------
+----TRLLIAEDQKMLLGALASLLDEDDIDVIGTVNNGKEAVEAVKKEKPDICIMDIEMPEMNGLDAAELLKD--DPCKILILTTFARSGYFQKAMSVGVDGYMLKDSPSEELAEAIRQIMQ----
+----TRLLIADDEQIEREGLEVILQKAGVE-ISQAKNGKMAVQLAKAFNPDLILMDIQMPGLNGLEAIKQISEADPHIKFIMITAFDTFDYARQAIKLGVKDYLLKPSKITEIEATVGKVLEQI--
+--TRLKILVVDDTKTNIDVLEGILSN-DYD-VCVALNGKKAIELTEKIRPDLILLDVMMPEMDGYETLRIMREKLQGIPVIFLTAKADSKSEQIGLDLGAVDYITKPFNPALVTLRIKNQL-----
+--TRLIVLVVEDEPLLRMTAVDMVEEAGLT-ALEAADATEAIRILESRDIRIVFTDIDMPGIDGIRLAAVIRHRWPPIDIIVTSGHVDAGEVDLPARC---KFLPKPYDERLVIAAMRSF------
+--TRLIVLVVEDEPLLRMTAVDMVEEAGFT-ALEAADATEAIRILESRDIRIVFTDIDMPGIDGIRLAAVIRHRWPPIDIIVTSGHVDAGEVDLPARC---KFLPKPYDERLVIAAMRSF------
+---TRKVVVADDHPIVLRAVTDYVNSLGFHVVASVSSGDALLSAMREQEVNLVVTDFTMHDKDGLRLISHLMRAYERTPIIVFTMLTNSGVISQLCRMGVAGLVGKEEEIAELGRVCVSVAR----
+---TRKVVVADDHPIVLRAVTDYVNSAGFHVVASVSSGDALLSAMREQEVNLVVTDFTMHDKDGLRLISHLMRAYERTPIIVFTMLTNSGVISQLCRMGVAGLVGKEEEIAELGRVCLSVAR----
+--TRKTILVVDDDPHILEVLEVRLVSAGYD-VVPAANGLEALEVLSRQPVRLVISDMRMPGMDGMRMLEEMERRGIKLPIIFLTAHGSIPGAVEAIKHGAVDYLTKPFDGQELLARVTDVFAKA--
+--TRKTILAVDDDPHILEVLEVRLVSAGYD-VVTAGDGAEALEVLAKRPVKLVISDIRMPGMDGMRLLEEMERRGIRLPIIFLTAHGSIPGAVEAIKHGAVDYLTKPFDGQELLTRVTEVFARA--
+--TRKQILVVDDDLRLRGLVESHLQGFGFG-VRGMSDGRQIESLLAEAPVDLIVLDLGLPHEDGLQICRRLRQH-HDVPILMLTARGDEVDRILGLEMGADDYLAKPFHPRELVARIQAILRRV--
+----------------------------------------------TRKPDLVILDLGLPDGDGIDFIRDFRG-WSGAPLIVLSARSAEAAKVAALDQGADDDLGKPFGVAELLARVRA-------
+----------------------------------------------TRKPDLIILDLGLPDGDGLSYIQDLRQ-WSAIPIIVLSARNSEEDKVAALDAGADDYLSKPFGISELLARVRVALRRHS-
+--TRKNILIVDNNCELEQLVKEQLENSGFSVVVRAKDGAEAAIKSENQKFDVVLIDTEVPRMDGG-FVYGIHTNTQDAELIVISQRDS-SDLPESLQS--SKFFKKPVSPNELISAMISVLNA---
+--TRKKILIVDDSAVIRKSIEMALAETGYG-LISAATGEAAIKLATEQKPDLILLDVMLPDTTGLKVCKTLRSELKTTPIVMLSAKDAEIDKNLGLHAGANDYVTKPFKDGQLVEIVDKFLK----
+---TRKILLIEDNPEMRENTAEILELANYE-VLTAQNGKEGVQQASQHLPDLIICDIMMPELDGYGVLHMLGKRTASVPFIFLTAKAEKEDYRKGMTMGADDYLTKPYDDVELLNAVEMRLKKS--
+-----------------------------------TRKGDLLDALKQDKPALIVMDWNMAARKGYVVLSWLAQSWQVIPVVIMTDAHKPVDEVKCAQLGYELVLPKEPSYTKQLKQLRGLVR----
+----TRIVVVEDEIDIASVVQDYLRHSGYE-TAHFADGQSALESIVAAPPDLTLLDIMLPRLDGIEVLRRAREH-TAHPIIMLTARIEEVDRLLGLELGADDYVCKPFSPRELVARVRAVLRRT--
+----TRIVVAESDRDFRARLKEILRHAGYMVIGETQDGRSLLQMVFQTTPELVILEYRLPGSEGIDVAGIIEEH--HVAPVVLTADLHQQNVAELVRSGVYGVLPRPLQEEMVVPTIEMAMS----
+----TRIVVADSCTLLCQGLSRLLEEADLRVTGAYTRGREALRAVLETRPDVFLVDTRLEDVDAFVVVGEVRRARPEVRVVVFSAQPEAREVRQAYEAGAAAFVEKRADLGALLQVIRRVRR----
+----TRIVVAAYRTILVEGMVALLQKVGIEVVGHAEDGLACLQIAARERPDIVLVDVLLPGLNGIDLTRRLMQRSPNSRAICIAPSDACTQASAVFEAGAKAYLARTSRFAELLRAIQCVIQDQ--
+----TRIVLADDHVILREGLRALISQPDLEVVGEAASGTETVDCVRATEPRVLCLDLSMPGWGSATTITRVTQLAPRTRVLVLTMHNDPAYVRSALAAGAAGYFLKTTPSPDLLAAIRAVAT----
+----TRIVLADDHDLLRQGLTLLLQQADMRVVGEARNGLEAIKLVQEQRPDIVVMDISMAQLDGLEACERIRALAPGTQVLMLTMHESEEYFLQSLKKGAAGYIVKKAAPAELCNAVRTIA-----
+----TRIVIVEDELDIASVVQDYLRHAGYE-TTHFADGQSALDHLIATPPELTLLDIMLPRLDGIEVLRRAREH-TSHPIIMLTARIEEVDRLLGLELGADDYVCKPFSPRELVARVRAVLRRT--
+----TRIVIIDDEPQIRKFLDIALRTQKYK-TTLCETGYKGLETLATQGADLVILDLGLPDLDGREVLQELRS-WSNVPVIVLSVRADEYEKVALLDAGANDYMTKPFSVQELLARIRVILRNQ--
+----TRIVIIDDEPQIRKFLDIALRTQKYK-TTLCETGYKGLETLATQGADLVILDLGLPDLDGKEVLQELRS-WSNVPVIVLSVRADEYEKVALLDAGANDYMTKPFSVQELLARIRVILRNQ--
+----TRIVIIDDEPQIRKFLDIALRTQKYK-TTLCETGYKGLEALATQGADLVILDLGLPDLDGKEVLQELRS-WSTVPVIVLSVRADEYEKVALLDAGANDYMTKPFSVQELLARIRVILRNQ--
+----TRIVIIDDEPQIRKFLDIALRTQKYK-TTLCETGYKGLEALATQGADLVILDLGLPDLDGKEVLQELRS-WSNVPVIVLSVRADEYEKVALLDAGANDYMTKPFSVQELLARIRVILRNQ--
+----TRIVIAEDSAILREGLAQLIAERGHDVVAAVGNADDMLGAVREFAPDVVVVDIRMPTDEGLVAAVSLRRSHPEVGVLVFSQWVETRYATELLAGNAEGYLLKDADIAEFDAALQRVAAR---
+----TRIVIAEDEALIRLDLKEMLEEEGYTVVGEAGDGETAVRLVEELKPDLAILDVKMPVLDGLSAAERIHEQ-HLAPVLMLTAFSQRELVDRARDAGAMAYIVKPFSKSDLVPAIEMAVSRY--
+----TRIVIADDESLIRMNLRETLVGLGYLVVGEAGDGVSVINLARELRPDVVVMDIKMPKLDGIQAAKVLTEE-KIAPVLLLTAHSDKELVERARDAGVVGYLSKPFRDSDLMPALEI-------
+----TRIVIADDDHLMRAGLVELVTDPSIQVVGEAATGREAVTQTQRLRPDVVLMDVRMPDLDGIAATRELATRVPETRVLILTTFEQDDYVFGALRAGASGFLLKRTRPEDLIAAVHTVA-----
+----TRIVIADADRVFLKKLKDSLTHVGYMVVGEVYDAKSALQVIFKTEPDLIIMDSNIPGCEGLEIARVIEEH-RVAPVLLLTAYSQRELIEEAKHSWVFGYLLKPINQENLFPAIEIAIA----
+--TRITVLLADDNLIVREGVRALLSQADISVIGVAADHDELVRAAGRLRPEVVVTDIRMPTDEGVRAAQLIRAANPATGIVLLSQYDEPDYAIALLRDGASGYLLKEADPDLLARAIREVA-----
+----TRITIVEDQTILLDSLASAIDEDDFTVVDKLTDAAAIHASVRIHPVDLVLMDVVTENSSGLSESTKLKRDHPNLKVVIFTAMPDAAFLQEAHEAGVDSFVYKNISTPDLLAVLRSTMQ----
+----TRITIVEDQTILLDSLASAIDEDDFTVVDKLTDAAAIHASVRIHPVDIVLMDVVTENSSGLSESTKLKRDHPNLKVVIFTAMPDAAFLQEAHEAGVDSFVYKNISTPDLLAVLRSTMQ----
+--TRIRVVVAEDQLAVRAGLVLILRSADIEVVAEAADGEQAVRLARELRPDLVLMDIQMPRLDGVSATREIAAE-QLADVLILTTFDLDEYVFGALRAGAAGFLLKDSDAAGLLAAVRTVAS----
+--TRIRILCVDDHPIVRDGIAYALQQNDMELVAEATNGHEAIEAFRKHKPDVTLMDLQMPGMSGIEATAEIRKEFPQARIVILTTYSGDIQASRALKLGAVGYLLKGMLRTELVDTIRRVYA----
+----TRINLVEDEKNLNSVLTSYLEKEGWE-VKSFKNGSDAFDEID-DSPDIWILDIMLPGIDGFELLREIRKRDSMIPVIFISARDKDIDRVVGLEMGSDDYLPKPFLPRELVIRVKKILERV--
+----TRIMLVEDEASLSEPLAFLLQREGYE-VDVVEDGPAAVASFDKDGADLILLDLMLPGLPGTEVCREIRTR-SAVPIIMLTAKDSEVDIVVGLELGADDYVTKPYSTRELLARIRAVLRRR--
+----TRIMLVEDEASLSEPLAFLLQREGYE-VDVVEDGPAAVAAFEKDGTDLILLDLMLPGLPGTEVCREIRTR-SAVPIIMLTAKDSEVDIVVGLELGADDYVTKPYSTRELLARIRAVLRRR--
+----TRIMIVEDQTMVRDALRNSLDIEDFSVIAAIADAALAELYCERTSPDLVLMDVCTEDSSGLDAAAAIKKRFPRVRVVMMTGLPEVTFVERAREAGADSFVYKDLDVNGLAGVIRDTCA----
+----TRIMIIEDEPLIAMDIEQMVESLGHEVVGIARTRDEALALYRQEKPRMVLADIQLAGSSGIDAVNEILQN-DAIPVIFITAFP--ERLLTGERPEPTFLVTKPFNPDMVKALISQAL-----
+----TRIMIIEDEPLIAMDIEQMVESLGHEVVGIARTKDEALALYKQEKPRMVLADIQLAGSSGIDAVNEILQN-DTIPVIFITAFP--ERLLTGERPEPTFLVTKPFNPDMVKALISQAL-----
+----TRILYIEDDEALGRLLQKRFRRHSLE-VDLAVTAEVGLEVIAQREFDLILLDYNLPGMNGLETLKALKAREVTTPVIILTAGGDEAIALEAMELGAADYAVKDINQAYL-------------
+----TRILVVEDNEINQEVICNLLEIVGLR-VDLASSGEQAIEMACRDRYDLILMDIQMPELDGVQATRRLRERWLSCPILAMTANVFEDERRRYLREGLDDHIPKPVDPPHLYAVLLKWLAR---
+----TRILVVEDEVSFSDPLSYLLRKEGYE-VSVAENGNDALTEFDSGGADLVLLDLMLPGLSGVDVCRALRQR-SNVPVIMLTAKDSEIDKVVGLELGADDYVTKPYSSRELLARIKAVLRRL--
+----TRILVVEDESIVAKDIQTTLQSLGYSVPAVVSSGEAAIDRAAVSDLDLVLMDIVLKEMDGVEAAEHIYGN-FNIPVIYLTAYADDHTLRRAKTTTPFGYILKPFEERELQTAIEIALYRHK-
+----TRILVVEDEPSYLDPLLYQLTREGYE-AHGAATGEEAWELYEEMEFDLVLLDLMLPGISGTTLCRRMHEL-RRVPIIMVTAKSTENDVIVGLEIGADDYVTKPYSFRELLARIHAVLRRS--
+----TRILVVEDEESYREPLTYQLTREGYD-VVAVATGTEALSAYDDEQPDLVLLDLMLPGLSGTEVCRELRSR-GDVPVIMLTAKDGEIDKVVGLELGADDYVTKPYSFRELLARMRAVLRRHT-
+----TRILVVEDEESYREPLTYQLTREGYD-VVAVADGAAGLAAYDEGGADLVLLDLMLPGLSGTEVCRELRQR-GDVPVIMLTAKDGEIDKVVGLELGADDYVTKPYSFRELLARVRAVLRRR--
+----TRILVVEDEESYRDPLTYQLAREGFD-VVAAADGLEAIEKFEADGIDIVLLDLMLPGLSGTEVCRRLRLV-SDVPVIMLTAKDTEIDKVVGLELGADDYVTKPYSFRELLARVRAVLRRR--
+----TRILVVEDEESFSDPLSYLLRREGYD-VAVTETGPEALEEFDKAGADLVLLDLMLPGLPGTEVCRQLRTR-SSVPVIMLTAKDSEIDKVVGLEIGADDYVTKPYSSRELLARVRAVLRR---
+----TRILVVEDEEMVRANIVDLLEAEGYE-TQEASDGEQALQLIWQNPPDLILCDVRMPRVDGFTFLARISQRLRAIPFIFLTARVEREDQRLGMNLGADDYITKPFTRKDLLTAVQRRLEKH--
+----TRILVVEDEEKIARFVELELRHEGYE-VDKAADGRSGVEAALSSDYDLVLLDVLLPQLNGMEVLRRLRRQ-KDTPVILLTARDAVMDKVAGLDAGADDYITKPFAIEELLARIRVTLKH---
+----TRILVVEDEDSYRDPLTYQLTREGYE-VVEASNGHDALAAFDDGGADLVLLDLMLPGLSGTEVCRELRQR-GDVPVIMLTAKDSEIDKVVGLELGADDYVTKPYSFRELLARMRAVMRRR--
+----TRILVVEDDPSIARLLQLELEHRGYE-VCCAADGEEGLAAFERLRPDVVVLDIMLPGMDGVGVLRRLREAGHRTPVIMLTARDATGDKVHSLDRGADDYLTKPFEVEELLARMRAVLRRV--
+----TRILVVDPSYSNRLYLKLTLERAGYQ-VFDAKDGKEALNQFKQFQPHLVITEIDLPLLSGESLVSEIKSEETFYPIFVVTNVTSPESIQEILEAGADDFLQKPYPEKLFLAKVASLLRNL--
+----TRILVVDDSKTIRRSAEVLLTKAGCE-VQLAEDGFEALGKVVSFKPDLVFVDIMMPRLDGYHTCALIKNQLRDTPVVMLSSKDGLFDRAKGRLVGARLYLAKPFTADELIGAVRASL-----
+----TRILVVDDSATNLRILDGQLRQMGLG-VETLSDPTRTLARLHHSPFQIAILDRYMPVLDGIELARRIRAILQRMKVVMLTSASHLGELDRVRQLGLDAFLVKPTRQLQLRQSLARVL-----
+----TRILVVDDQALVRGALAALLDEDDLQVVGQVDSGPAAVDFVRDTSVDVVLLDIEMPGGGGIDALPDLLTAPTPPRVLVVTTFGRPGYLRRALDAGASGFVVKDCPPTELLEAVRRTA-----
+----TRILVVDDHAVVRQGVKQILSEQFHGVLGDAQNAEEMILQVGKHSWDIVILDVGMPGKSGLDALKELKQARPKLPVLVLSGYPEDQLALRMLKAGAAGYLSKDSAPNELVQALRKIL-----
+----TRILVVDDHAVVRAGVHYFIDDIDMEIGGEAGTAEEAIRLIRAEDWDIVVLDIAMPDKSGVEVLKQIKREKPDLPVLILSMHPENRYAVQILRSGASGYVQKEALATELVNAIQTIMRGH--
+----TRILVVDDEPQILRALRINLTARGYE-VVTAADGRSALRAAAQQRPDVIVLDLGLPDLDGIEVLAGLHG-WCSAPVIVLSARSDAADKVAALDTGADDYVTKPFGMEEFLARIRAAVRRAA-
+----TRILVVDDEPQILRALRINLSVRGYD-VVTAASGAAALRAAAERPPDVIVLDLGLPDMDGTEVLAGLRG-WCPAPVIVLSARTDSADKVDALDAGADDYVTKPFGMDEFLARVRAAARRAT-
+----TRILVVDDEPQILRALRINLRARGYD-VEVAGSGAAALKAAAGHPPDLVVLDLGLPDLDGTDVIRGLRG-WTAVPIIVLSGRAGSEDKVAALDAGADDYVTKPFGVDELLARIRAVTRRL--
+----TRILVVDDEPQILRALRINLRARGYD-VEVADSGAAALKAAAGHPPDLVVLDLGLPDLDGTDVIRGLRG-WTAVPIIVLSGRAGSEDKVAALDAGADDYVTKPFGVDELLARIRAVTRRL--
+----TRILVVDDEPQILRALRINLKSRTYD-VETVANGVDALASAARRLPDAVLLDLGLPDMDGVEVILGLRG-WTTVPIVVLSGRTDPQEKIHALDAGADDFVTKPFAMEELLARLRAVIRRHQ-
+----TRILVVDDEPPIRTVLRGYLEAEGFV-VSEAADGAAALAELRAEPVDLVLLDVMMPGMDGLEVLRRLRTV-ADTYVILVTARSEEVDKLVGLGVGADDYVTKPFSPREVTARVKSVLRRR--
+----TRILVVDDEPKLGKVVAQMLELDGHE-VERAAGGRDALVRLAASRFDVVVTDLRMPDVDGLAVLRAARAVPQPPEVVVMTAYATAESAVEAMKAGAVDYVTKPFSMDELRLRVRRLAAQR--
+----TRILVVDDEPDMLQAMERILPREDLE-VVVRDRATAGLEVIRQPGADVLLCDIRMPEMDGLELLAAAKEIDPWLTVVMMTAYGGIETAVKAVKSGAYDFITKPFEIPDLVRVLHKALERS--
+----TRILVVDDELSMREFISILLEREGYE-VLTAADATTALTRLAASDIDLVISDVQMPGLSGLELLARIKENKPDTAVLLITAFSTAEQAVEAMKLGAYDYLAKPFKVDEIKILVKNALEKR--
+----TRILVVDDEADLEVLIKQKFRKKEYE-FFFALNGKKALEVMEEKDIDMILSDINMPEMDGLTLLSKVKEQHSLLKTVIISAYGDMDNIRTAMNLGAFDFITKPVDFQDLEITIEKTIESI--
+----TRILVVDDDTALAEMIGIMLESEHYE-PFFCADGAQALATFREVNPHLVLLDLMLPGLDGVEICRLIRAE-SDVPVIMLTARTDTQDVVAGLEAGADDYVTKPFKSKELLARVRTRLRR---
+----TRILVVDDDSEIRELLDEYLSRNGYQ-VATVADGHQLKHYLAENGPELVLLDIMLPGEDGFSLCQFMRRE-STVPIIMLTAVSEETDQIIGLEIGADDYIAKPFNPRHLVARIKAVLRRV--
+----TRILVVDDDPSIAEMLALLLESEGFE-VSVCATGNNALPLFRADRPDLVLLDVMLPGLDGVSVCRLIREE-SDVPIIMMSARTDSVDVIAGLEAGADDYVTKPFENSVLLARVKARLRRQ--
+----TRILVVDDDASLAEMIGIMLESESYT-PTLCHDGAKALDAFHEVSPDLVLLDLMLPGLDGVEICRLIRSE-SDVPIIMLTARTDTQDVVAGLEAGADDYVTKPFKSKELLARVSTRLRRT--
+----TRILVVDDDASLAEMIGIMLESESYT-PTLCHDGAKALDAFHEVNPDLVLLDLMLPGLDGVEICRLIRSE-SDVPIIMLTARTDTQDVVAGLEAGADDYVTKPFKSKELLARVSTRLRRT--
+----TRILVMDDNPEVLEAYRAIFSAQVFE-LVAVSQGQDGVAEVERRPFAVAFVDIRMPGMDGLEVARRIRALDAHIYINIVSAYSDHDEIHDQLQHDV-QFIKKPVSRGELYQMARDGCER---
+----TRILVIGNVNEHCESIESYLKPFNIQ-TKNAQDLDRASQKMMDYSPQIIFINHMVSGVSSSVIISKLKTGSKSVRFVLLKNSNTEEEGIDYQTLGFNQCINKPIKQKSLFNALRKI------
+----TRILVIEDETEIASFLRRGLSLEGYQ-VDVAFDGTRGLELASTGTYDLIVLDLMLPGIDGLEVARRLRAD-SNVPIIMLTARDAVRDRVAGLEAGADDYLVKPFAFEELLARIRAQLRRR--
+----TRILVIEDDEETASFIANGLKQEGFA-VDTAKTGTDGLFQATESPPDLVVVDRMLPGLDGVSVIKALRAAGVKIPVLFLTAMGAVEDRVAGLEAGGDDYLVKPFSFMELRARVTTLLRR---
+----TRILVIDDMPSIRDLVKNTLKAMGYKNLQEAEDGEAGLKILIQNQIQLVISDWNMPKMKGLELLKQVRAEFANLPFVLLTSESERDQVTEAVLAGVSQYIVKPFSAKIFEDKLKAAYSKH--
+----TRILVIDDEEDILALIKNTLQLQNYL-VKTFVSANQ-VDRSKLADYDLILLDIMMPDVDGLSFCRDIRNL-VDCPILFLTAKSQEADVVTGLSYGADDYICKPFGVQELLARVDAHLRRE--
+----TRILVIDDDRSFIHHMQTALRGLGE--VRVTTCGVDGLRTVEHWEPDVVMLDLLLHDVDGFTLLERLTGDCRHRPAV---------------------------------------------
+----TRILVADDHRLIAESVSLSLSSEGFD-VEISDSLSSTLEKIISEPYSIVMLDLRMPGMDGINSIKKVVDAAGDANVVLFSANADTHTVARAIEVGVRGLVPKTLPLQSLGSVLR--------
+----TRILVADDHPLFREALSGALGPYNAQ-ILEAGSLDAALAVLNEDGIELVLLDLNMPGGEYFNGIITLREQYPNIPIGVVSGSDAVEVVAQVMSLGAQGFIPKVSATREMAQAIVDII-----
+----TRILVADDHPLFREALSGALEPYNAQ-IIQAGSLDDAMAKLNEDGVELILLDLNMPGGEYFNGLITLREQYPNIPVGVVSGSDTVEVVAQVMSLGAQGFIPKVSQTREIAQAIVDII-----
+----TRILVADDHPLFREALSGALEPYNAQ-IIQAGSLDDALEKLNEDGVELVLLDLNMPGGEYFNGLITLREQYPNIPIGVVSGSDTVEVVAQVMSLGAQGFIPKVSETREIAQAIVDII-----
+----TRILVADDHDLVRMGIVRMLQDEGFEVVGEAKTGEQAIALSRELQPQVVLMDVKMPGIGGLEATRKILASCSHTRVVAVTAVSDDLFPERLMKAGASGYVTKGAGFDEIIDAVHSVMN----
+----TRILVADDHAIFREGLKQVIGTVDMSVVDEAVDGKELLNKIQANDYDMVILDITMPGRNGLDVLTEMKSIKPKLPVLVMSMHPEEQYALRAYKSGAAGYLNKGSASNELLDALHKI------
+----TRILVADDEHLIRNAIAGLLEEDGFEVVGQAASGDEALATALRVRPDVALLDLQLPGPDGIEVARRLAAQLPECRSIIVTSHARPGYLKSALAAGARGFLPKTVSPRTLAQVVRTVV-----
+----TRILVADDEHLIRDAVAGLLDEEDFEVVAQAASGDEALAMALKLRPDVALLDLQLPGPDGIEIARRLATELPGCRCVIVTSHGRPGYLKSALAAGVSGFLPKTVSSRTFAEVVRKVA-----
+----TRILVADDEESMRWVLSKALKRKGFT-VDLADDGRQALALIQENSYDLAILDIKMPGMSGLDLLDRIREMKSDLLVVIMTAEASMKNAVEAMKRGAYDYITKPFDLDVIDAIVEKVGR----
+----TRILTIEDDAVTAREIVAELSSHGLD-VDWVDNGREGLVRAVSGDYDLITLDRMLPELDGLAIVTTLRTIGVSTPILMISALSDVDERVRGLRAGGDDYLTKPFASDEMAARVEVLLRRKS-
+----TRILTIEDDAVTAREIVAELSSHGLD-VDWVDNGREGLVRAVSGDYDLITLDRMLPELDGLAIVTTLRTIGVSTPILMISALSDVDERVRGLRAGGDDYLTKPFASDEMAARVEVLLRRKN-
+----TRILTIEDDAVTAREIVAELSSHGLD-VDWVDNGREGLDRAVSGNYDLITLDRMLPELDGLAIVTTLRTMGVATPILMISALSDVDERVRGLRAGGDDYLTKPFATDEMAARVEVLLRRQN-
+----TRILQVEDDIISQRFMNQLCKIAGWK-IKIASNGLEALNILENEDFDIILMDIQMPDMSGIELTKIIRETGKHITIIAMTAYAMGGDRDICINTGMDDYISKPIEVMKLKEVITKYSS----
+----TRILMIEDDMELAEILTEYLENYDIK-VTTAEEPYIGLSTLNTSEFDLVILDLTLPGMDGLEVCKEIRKK-HNIPIIISSARHDITDKVNALDNGADDYLPKPYDPQELLARIKSHLRRQS-
+----TRILLYSDEPILAKGLESVLRQEGFDLLPTCNTLAALMEQITQGTPDLVLMDLTPEV--TFAVLSEMKHAMNNSRIVLWVNSISTELAFQAMGLGVRGILRKTLPTELQVKCLQKV------
+----TRILLVHEIPLWRVALRALLTGTDLH-VDTAGPGDVGR-AAGTCPPDVYVLDLDCPGLTEIETFRASRDTADTGALVILTKGERPGDLRRAFHAGAGGYVDKYGETGDLAAVVRKVA-----
+----TRILLVEDNEMNRDMLSRRLSRRGFE-VLIAENGQAGVELAASEKPDLILMDMSLPVMDGWEATRRIKALTSAIPVIALTAHAMASDREMALKAGCDDYDSKPVDLPQLVRKIEQLLT----
+----TRILLVEDNEMNRDMLSRRLSRRGFD-VLIAENGKDGVEIAASERPDLILMDMSLPVMDGWEATRQIKANTCGIPVIALTAHAMASDRDMALDAGCDDYDSKPIDLPQLVRKIEQLLT----
+----TRILLVEDNEINQQVARAILEEVGLV-CDLAENGEEAVAMIGKARYALALMDMQMPRMDGVTATQAIRQLGKDIPIVAMTANAFNDDVQRCLASGMNDFLLKPVDPDKLYDTLLKW------
+----TRILLVEDEESYREPLTYQLEREGYE-VVAAADGLQAIELFEEHGADLVLLDLMLPGLPGTEVCRRLRLT-SDVPVIMLTAKDDEIDKVVGLELGADDYVTKPYSSRELLARMRAVLRRR--
+----TRILLVEDEESYRDPLSYQLGREGYD-VVTAATGPEALERFAEHGADLVLLDLMLPGLPGTEVCRRLRL-DSDVPVIMLTAKDDEIDKVVGLELGADDYVTKPYSSRELLARIRAVLRRR--
+----TRILLVEDEESISDPLAYLLGKEGYD-VTVAADGLQALAEFDSHGADLVLLDLMLPGASGTEVCRQLRAK-SKVPIIMLTAKDSEIDKVVGLELGADDYVTKPYSSRELLARIRAVMRRN--
+----TRILLVEDEENYREPLAFNLRRDGYD-VVEAEDGAVAVELFEEEPIDLVLLDLMLPRLSGTEVCRRIRRS-SNVPVIMLTAKDSEVDKIVGLEIGADDYVTKPYSYRELVARVHAVLRRT--
+----TRILLVEDEENFRDPLAYGLRRDGFE-VVEAEDGQRAVEIFEASRIDLVLLDLMLPRLDGTGVCTRIRRS-SSVPVIMLTAKDTELDKIVGLEIGADDYVTKPYSYRELLARLKAVLRRS--
+----TRILLVEDEENFRDPLAYGLRRDGFE-VVEAEDGQRAVEIFEASRIDLVLLDLMLPRLDGTEVCTRIRRS-SSVPVIMLTAKDTELDKIVGLEIGADDYVTKPYSYRELLARLKAVLRRS--
+----TRILLVEDEENFRDPLAFSLRRDGFE-VIEAEDGQRAVEIFETSRIDLVLLDLMLPRLDGTEVCTRIRRS-SSVPVIMLSAKDTELDKIVGLEIGADDYVTKPYSYRELLARLKAVLRRS--
+----TRILLVEDEDSFSDPLSYLLGKEGYE-VTVADDGLKALAEFDRNGADLVLLDLMLPGVSGTEVCRELRVK-SSVPIIMLTAKDSEIDKVVGLELGADDYVTKPYSSRELLARVRAVLRRN--
+----TRILLVEDDPLIVDSLTELLAGSGYS-VDTADTQQRAIELAVDHPYQLILLDVTLRQGNGFAVCAAVKEATPDVPVIFLTASDDEFNTVTGLTMGADDYVAKPFRPRELLARIAATIRRS--
+----TRILLVEDDPLIVDALTELLTSSGYS-VDTADTQTRAIELATGGTYQLVLLDVTLREGNGFAVCAAVKETSPSTPVIFLTASDDEFNTVTGLTMGADDYVAKPFRPRELLARIAATIRRS--
+----TRILLVEDDLLLSEGISYALRKESYL-VDCADSIEKAWECLNK-GPSLVLLDVNLPDGDGREFLKRLRSA-NKVPVVFLTARDSEKDMLEGFDAGCDDYITKPFPISVLSRKIGLLLK----
+----TRILLVEDDEVMPKIMERILHKEEYK-IEHVTNGKEAFQRLEDNNYDLIITDIMMPYANGFEILSKVKTRGKPIPVIIVSNAGNEEMILEGFKLGADDFLKKPVIPGELLIRVKRLLIQ---
+----TRILLVEDDERLAELTAEYLTKNDLE-VSIEPRGDTAEARILAEQPDLVILDVMLPGKDGFEVCRAVRSQF-RGVILMLTARDEDFDQILGLEMGADDYIAKPVQPRVLLARIKALLRRL--
+----TRILLVEDDAGMQRIVSDHFADHDVA-VTAATDRAEAEKRLAEAEFDLVVLDLRLGSENGLDLLRDLRAR-SDLPVIITTGHRRDEDRVIGLELGADDYLVKPYGLRELLARVRVILRRAE-
+----TRILLVDDQPQFRRAAAALIGTAGLRLVGQAGSGEEAVELADRLRPDLIVMDVRLPGIDGTEACRRIRHRRPDIRVILVSTYER-ADLPGIDDCGATRFVRKQ-------------------
+----TRILLVDDHTIFRSGLRRLISKPEYCVAAEASNSAEALSLVRDQDFDVVILDINLNGRSGLEVLESIRRTKPNLRVLVMSMYPEAQFGAEAVRLGANGYLSKDTTPDALFDALRSAAQ----
+----TRILLVDDEAPIRRAVRRFLEHHGFQ-VRLAEDLASARAALREELPDLMLVDLRLPDGEGIELLAEAG----HTPTVIMTSYASVPSAVTAMKEGAADYIAKPFDHDALLLTLRAALR----
+----TRILLVDDDPTILDAFPVYFSTDDLEISGTARTGRQALTWLDTNTCDLVLSDVQMPDIDGIELLQHIRDLNRPPLFVAMTAFDTDDTMLKCLSLGAVGYIIKGRAPESIIHSLRDAT-----
+----TRILLVDDDAPLLRALRINLTARRYE-VTTATDGTTALTLAARTPPDLAIVDLGLPDLDGVTVVEGLRG-WTRIPIIVLSARDTESAKVDALDAGADDYITKPFGMNELLARIRAALRRA--
+----TRILLVDDAQIECLAFERQLHKIPFHQLDWVSTYADALVAFDRDQHDLYFVDFRLGPDNGLDLVRRARVNGMTKPIIVLTGHGSAAVDKAATDAGANDYLVKEFDAVLLERSIRYASRN---
diff --git a/lib/FreeContact.pm b/lib/FreeContact.pm
new file mode 100644
index 0000000..065520d
--- /dev/null
+++ b/lib/FreeContact.pm
@@ -0,0 +1,195 @@
+# Copyright (C) 2013 by Laszlo Kajan, Technical University of Munich, Germany
+#
+# This library is free software; you can redistribute it and/or modify
+# it under the same terms as Perl itself, either Perl version 5.10.1 or,
+# at your option, any later version of Perl 5 you may have available.
+#
+package FreeContact;
+
+use 5.010001;
+use strict;
+use warnings;
+
+require Exporter;
+use AutoLoader qw(AUTOLOAD);
+use Carp;
+
+our @ISA = qw(Exporter);
+
+# Items to export into callers namespace by default. Note: do not export
+# names by default without a very good reason. Use EXPORT_OK instead.
+# Do not simply export all your public functions/methods/constants.
+
+# This allows declaration use FreeContact ':all';
+# If you do not need this, moving things directly into @EXPORT or @EXPORT_OK
+# will save memory.
+our %EXPORT_TAGS = ( 'all' => [ qw(
+ get_ps_evfold
+ get_ps_psicov
+) ] );
+
+our @EXPORT_OK = ( @{ $EXPORT_TAGS{'all'} } );
+
+our @EXPORT = qw(
+
+);
+
+our $VERSION = '0.01';
+
+require XSLoader;
+XSLoader::load('FreeContact', $VERSION);
+
+# Preloaded methods go here.
+sub FreeContact::Predictor::run
+{
+ my $self = shift(@_);
+ if(scalar(@_)%2){ confess("Odd number of arguments"); }
+ my %args = (get_ps_evfold(), @_);
+ return $self->_run($args{ali},
+ $args{clustpc}, $args{sparsity}, $args{gapth}, $args{mincontsep},
+ $args{pseudocnt}, $args{pscnt_weight}, $args{estimate_ivcov}, $args{shrink_lambda},
+ $args{cov20}, $args{gap_incovm}, $args{veczw}, $args{rho},
+ $args{num_threads}, $args{timing}
+ );
+}
+
+# Autoload methods go after =cut, and are processed by the autosplit program.
+
+1;
+__END__
+# Below is stub documentation for your module. You'd better edit it!
+
+=head1 NAME
+
+FreeContact - fast protein contact predictor
+
+=head1 SYNOPSIS
+
+ use FreeContact;
+
+ open(EXAMPLE, '<', '/usr/share/doc/libfreecontact-perl/examples/demo_1000.aln') || confess($!);
+ my @aln = <EXAMPLE>; chomp(@aln); close(EXAMPLE);
+
+ my $contacts = FreeContact::Predictor->new()->run(ali => \@aln);
+
+ my $predictor = FreeContact::Predictor->new();
+ my %parset = FreeContact::get_ps_evfold();
+ my $contacts = $predictor->run(ali => \@aln, %parset, num_threads => 1 );
+
+=head1 DESCRIPTION
+
+FreeContact is a protein residue contact predictor optimized for speed.
+Its input is a multiple sequence alignment. FreeContact can function as an
+accelerated drop-in for the published contact predictors
+EVfold-mfDCA of DS. Marks (2011) and
+PSICOV of D. Jones (2011).
+FreeContact is accelerated by a combination of vector instructions, multiple
+threads, and faster implementation of key parts.
+Depending on the alignment, 10-fold or higher speedups are possible.
+
+A sufficiently large alignment is required for meaningful results.
+As a minimum, an alignment with an effective (after-weighting) sequence count
+bigger than the length of the query sequence should be used. Alignments with
+tens of thousands of (effective) sequences are considered good input.
+
+jackhmmer(1) from the hmmer package, or hhblits(1) from hhsuite
+can be used to generate the alignments, for example.
+
+=head1 FreeContact
+
+=head2 EXPORT_OK
+
+=over
+
+=item get_ps_evfold()
+
+=item get_ps_psicov()
+
+These functions return a hash of arguments (clustpc => I<num>,...,rho => I<num>) that can be used
+with run(). The arguments correspond to the published parametrization of the
+respective method.
+
+=back
+
+=head1 FreeContact::Predictor
+
+=head2 Constructor
+
+=over
+
+=item new( [DEBUG] )
+
+Creates an "FreeContact::Predictor".
+
+=back
+
+=head2 Methods
+
+=over
+
+=item run( ali => I<[]>, clustpc => dbl, sparsity => dbl, gapth => dbl, mincontsep => uint,
+ pseudocnt => dbl, pscnt_weight => dbl, estimate_ivcov => bool, shrink_lambda => dbl,
+ cov20 => bool, gap_incovm => bool, veczw => bool, rho => dbl,
+ [num_threads => int, [timing => I<{}>]] )
+
+Defaults for the arguments are obtained with get_ps_evfold().
+
+=over
+
+=item ali
+
+Reference to array holding alignment rows as strings. The first
+row must hold the query, with no gaps.
+
+=item TODO
+
+=item num_threads
+
+Number of OpenMP threads to use. If unset, all CPUs are used.
+
+=item timing
+
+If given, this hash reference is filled with data containing wall clock
+timing results in seconds:
+
+ {
+ num_threads => NUM,
+ seqw => NUM,
+ pairfreq => NUM,
+ shrink => NUM,
+ inv => NUM,
+ all => NUM
+ }
+
+=back
+
+run() returns a hash reference of contact prediction results:
+
+ {
+ fro => [ # identifier of scoring scheme
+ [
+ I, # 0-based index of amino acid i
+ J, # 0-based index of amino acid j
+ SCORE # contact score
+ ], ...
+ ],
+ MI => ...,
+ l1norm => ...
+ }
+
+=back
+
+=head1 AUTHOR
+
+Laszlo Kajan, E<lt>lkajan at rostlab.orgE<gt>
+
+=head1 COPYRIGHT AND LICENSE
+
+Copyright (C) 2013 by Laszlo Kajan
+
+This library is free software; you can redistribute it and/or modify
+it under the same terms as Perl itself, either Perl version 5.10.1 or,
+at your option, any later version of Perl 5 you may have available.
+
+=cut
+# vim:et:ts=4:ai:textwidth=78:
diff --git a/perlobject.map b/perlobject.map
new file mode 100644
index 0000000..4795c47
--- /dev/null
+++ b/perlobject.map
@@ -0,0 +1,106 @@
+# "perlobject.map" Dean Roehrich, version 19960302
+#
+# TYPEMAPs
+#
+# HV * -> unblessed Perl HV object.
+# AV * -> unblessed Perl AV object.
+#
+# INPUT/OUTPUT maps
+#
+# O_* -> opaque blessed objects
+# T_* -> opaque blessed or unblessed objects
+#
+# O_OBJECT -> link an opaque C or C++ object to a blessed Perl object.
+# T_OBJECT -> link an opaque C or C++ object to an unblessed Perl object.
+# O_HvRV -> a blessed Perl HV object.
+# T_HvRV -> an unblessed Perl HV object.
+# O_AvRV -> a blessed Perl AV object.
+# T_AvRV -> an unblessed Perl AV object.
+
+TYPEMAP
+
+HV * T_HvRV
+AV * T_AvRV
+
+
+######################################################################
+OUTPUT
+
+# The Perl object is blessed into 'CLASS', which should be a
+# char* having the name of the package for the blessing.
+O_OBJECT
+ sv_setref_pv( $arg, CLASS, (void*)$var );
+
+T_OBJECT
+ sv_setref_pv( $arg, Nullch, (void*)$var );
+
+# Cannot use sv_setref_pv() because that will destroy
+# the HV-ness of the object. Remember that newRV() will increment
+# the refcount.
+O_HvRV
+ $arg = sv_bless( newRV((SV*)$var), gv_stashpv(CLASS,1) );
+
+T_HvRV
+ $arg = newRV((SV*)$var);
+
+# Cannot use sv_setref_pv() because that will destroy
+# the AV-ness of the object. Remember that newRV() will increment
+# the refcount.
+O_AvRV
+ $arg = sv_bless( newRV((SV*)$var), gv_stashpv(CLASS,1) );
+
+T_AvRV
+ $arg = newRV((SV*)$var);
+
+
+######################################################################
+INPUT
+
+O_OBJECT
+ if( sv_isobject($arg) && (SvTYPE(SvRV($arg)) == SVt_PVMG) )
+ $var = ($type)SvIV((SV*)SvRV( $arg ));
+ else{
+ warn( \"${Package}::$func_name() -- $var is not a blessed SV reference\" );
+ XSRETURN_UNDEF;
+ }
+
+T_OBJECT
+ if( SvROK($arg) )
+ $var = ($type)SvIV((SV*)SvRV( $arg ));
+ else{
+ warn( \"${Package}::$func_name() -- $var is not an SV reference\" );
+ XSRETURN_UNDEF;
+ }
+
+O_HvRV
+ if( sv_isobject($arg) && (SvTYPE(SvRV($arg)) == SVt_PVHV) )
+ $var = (HV*)SvRV( $arg );
+ else {
+ warn( \"${Package}::$func_name() -- $var is not a blessed HV reference\" );
+ XSRETURN_UNDEF;
+ }
+
+T_HvRV
+ if( SvROK($arg) && (SvTYPE(SvRV($arg)) == SVt_PVHV) )
+ $var = (HV*)SvRV( $arg );
+ else {
+ warn( \"${Package}::$func_name() -- $var is not an HV reference\" );
+ XSRETURN_UNDEF;
+ }
+
+O_AvRV
+ if( sv_isobject($arg) && (SvTYPE(SvRV($arg)) == SVt_PVAV) )
+ $var = (AV*)SvRV( $arg );
+ else {
+ warn( \"${Package}::$func_name() -- $var is not a blessed AV reference\" );
+ XSRETURN_UNDEF;
+ }
+
+T_AvRV
+ if( SvROK($arg) && (SvTYPE(SvRV($arg)) == SVt_PVAV) )
+ $var = (AV*)SvRV( $arg );
+ else {
+ warn( \"${Package}::$func_name() -- $var is not an AV reference\" );
+ XSRETURN_UNDEF;
+ }
+
diff --git a/t/01FreeContact.t b/t/01FreeContact.t
new file mode 100644
index 0000000..d6b7336
--- /dev/null
+++ b/t/01FreeContact.t
@@ -0,0 +1,20 @@
+# Before `make install' is performed this script should be runnable with
+# `make test'. After `make install' it should work as `perl FreeContact.t'
+
+#########################
+
+# change 'tests => 1' to 'tests => last_test_to_print';
+
+use Test::More tests => 3;
+BEGIN { use_ok('FreeContact') };
+
+#########################
+
+# Insert your test code below, the Test::More module is use()ed here so read
+# its man page ( perldoc Test::More ) for help writing this test script.
+
+{
+ can_ok('FreeContact', qw(get_ps_evfold get_ps_psicov));
+ can_ok('FreeContact::Predictor', qw(new _run run));
+}
+# vim:et:ts=4:ai:
diff --git a/t/02test.t b/t/02test.t
new file mode 100644
index 0000000..666362c
--- /dev/null
+++ b/t/02test.t
@@ -0,0 +1,41 @@
+use strict;
+use warnings;
+
+use Scalar::Util 'reftype';
+use Test::More tests => 7;
+BEGIN { use_ok('FreeContact') };
+
+# /usr/share/doc/libextutils-xspp-perl/examples/Object-WithIntAndString/t/02test.t
+sub check_obj {
+ my $o = shift;
+ isa_ok($o, 'FreeContact::Predictor' );
+ can_ok($o, qw(new run _run) );
+}
+
+{
+ my %test_parset = FreeContact::get_ps_evfold();
+ my $o = FreeContact::Predictor->new(1); check_obj($o);
+ eval {
+ my $res = $o->run(undef, %test_parset);
+ };
+ like($@, qr/^Odd number of arguments/);
+}
+
+{
+ open(EXAMPLE, '<', 'examples/demo_1000.aln') || confess($!);
+ my @aln = <EXAMPLE>; chomp(@aln);
+ close(EXAMPLE);
+
+ my $num_threads = 1; # test will not work with 0
+ my $timing = {};
+
+ my $res = FreeContact::Predictor->new(1)->run(ali => \@aln, num_threads => $num_threads, timing => $timing);
+
+ is(reftype($res), 'HASH');
+ ok(($res->{fro}->[126+125]->[2]-8.08998)/8.08998 < 1e-6, 'precision test'); # [ 2, 3, 8.08998+- ]
+ ok($timing->{num_threads} == $num_threads, "timing results test");
+
+ #use Data::Dumper; warn(Dumper($timing));
+}
+
+# vim:et:ts=4:ai:
diff --git a/typemap b/typemap
new file mode 100644
index 0000000..a5a36df
--- /dev/null
+++ b/typemap
@@ -0,0 +1,93 @@
+# Copyright (C) 2013 by Laszlo Kajan, Technical University of Munich, Germany
+#
+# This library is free software; you can redistribute it and/or modify
+# it under the same terms as Perl itself, either Perl version 5.10.1 or,
+# at your option, any later version of Perl 5 you may have available.
+# Example: /usr/share/perl/5.10.1/ExtUtils/typemap perlobject.map
+TYPEMAP
+cont_res_t T_CONT_RES
+predictor* O_OBJECT
+ali_t T_ALI
+std::string T_PV
+time_res_t* T_TIME_RES_PTR
+
+INPUT
+T_ALI
+ {
+ if(SvROK($arg) && SvTYPE(SvRV($arg)) == SVt_PVAV)
+ {
+ // $arg is an array reference to strings - the sequences in the alignment
+ AV *arr = (AV*)SvRV($arg);
+ I32 seqcnt = av_len(arr)+1; // av_len returns highest index
+ if(seqcnt > 0)
+ {
+ SV** lineptr = av_fetch(arr, 0, false);
+ if(lineptr != NULL && SvPOK(*lineptr))
+ {
+ STRLEN alilen = SvCUR(*lineptr);
+ if(alilen <= 0xFFFF)
+ {
+ $var = $type(alilen);
+
+ for(I32 k = 0; k < seqcnt; ++k)
+ {
+ SV** lineptr = av_fetch(arr, k, false);
+ if(lineptr != NULL && SvPOK(*lineptr))
+ {
+ STRLEN alilen = SvCUR(*lineptr);
+ if(alilen <= 0xFFFF)
+ {
+ const char *al = SvPVbyte(*lineptr, alilen);
+ $var.push(std::string(al, alilen));
+ }
+ }
+ }
+ }
+ else croak(\"${Package}::$func_name() -- $var\->[0] is too long\");
+ }
+ else croak(\"${Package}::$func_name() -- $var\->[0] is not a character string\");
+ }
+ }
+ else croak(\"${Package}::$func_name() -- $var is not an AV reference\");
+ }
+T_TIME_RES_PTR
+ $var = (time_res_t*)~NULL;
+
+OUTPUT
+T_CONT_RES
+ if($var.empty()) $arg = &PL_sv_undef;
+ else
+ {
+
+ // return { 'l1norm' => [ [ 0, 1, 45.786 ], [ 0, 2, 7.993 ], ... ], ... }
+ HV* res = (HV*)sv_2mortal((SV*)newHV());
+ for(cont_res_t::const_iterator cr_i = $var.begin(), cr_e = $var.end(); cr_i != cr_e; ++cr_i)
+ {
+ AV* contacts = (AV*)sv_2mortal((SV*)newAV()); av_extend(contacts, cr_i->second.size()-1); // extend to index
+
+ for(std::vector<contact_t>::const_iterator ct_i = cr_i->second.begin(), ct_e = cr_i->second.end(); ct_i != ct_e; ++ct_i)
+ {
+ AV* ijscore = (AV*)sv_2mortal((SV*)newAV()); av_extend(ijscore, 2); // extend to index
+
+ av_push(ijscore, newSVuv(ct_i->i));
+ av_push(ijscore, newSVuv(ct_i->j));
+ av_push(ijscore, newSVnv(ct_i->score));
+ //
+ av_push(contacts, newRV((SV*)ijscore));
+ }
+
+ hv_store(res, cr_i->first.c_str(), cr_i->first.length(), newRV((SV*)contacts), 0);
+ }
+
+ sv_setsv($arg, newRV((SV*)res));
+ }
+T_TIME_RES_PTR
+ if($var && SvROK($arg) && SvTYPE(SvRV($arg)) == SVt_PVHV)
+ {
+ // return { 'key' => 0.0, ... }
+ HV* res = (HV*)SvRV($arg);
+ for(time_res_t::const_iterator tr_i = $var->begin(), tr_e = $var->end(); tr_i != tr_e; ++tr_i)
+ hv_store(res, tr_i->first.c_str(), tr_i->first.length(), newSVnv(tr_i->second), 0);
+ }
+
+# vim:noet:ts=4:ai:syntax=sh:
diff --git a/typemap.xsp b/typemap.xsp
new file mode 100644
index 0000000..f847ec3
--- /dev/null
+++ b/typemap.xsp
@@ -0,0 +1,18 @@
+/* Copyright (C) 2013 by Laszlo Kajan, Technical University of Munich, Germany
+
+ This library is free software; you can redistribute it and/or modify
+ it under the same terms as Perl itself, either Perl version 5.10.1 or,
+ at your option, any later version of Perl 5 you may have available.
+*/
+%typemap{cont_res_t}{simple};
+%typemap{parset_t}{simple};
+%typemap{predictor*}{simple};
+%typemap{ali_t&}{simple};
+%typemap{double}{simple};
+%typemap{U16}{simple};
+%typemap{bool}{simple};
+%typemap{std::map}{simple};
+%typemap{std::string}{simple};
+%typemap{time_res_t*}{simple};
+
+// vim:noet:syntax=cpp:ts=4:
--
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