[med-svn] [roary] 01/07: Imported Upstream version 3.5.7+dfsg
Sascha Steinbiss
sascha at steinbiss.name
Sun Dec 20 14:17:49 UTC 2015
This is an automated email from the git hooks/post-receive script.
sascha-guest pushed a commit to branch master
in repository roary.
commit 5b94ea18ab9b2346f0f40040da63a6bd1c4402d7
Author: Sascha Steinbiss <sascha at steinbiss.name>
Date: Thu Dec 17 15:29:00 2015 +0000
Imported Upstream version 3.5.7+dfsg
---
.gitignore | 36 +
.travis.yml | 29 +
AUTHORS | 2 +
GPL-LICENSE | 680 ++++++
README.md | 92 +
bin/create_pan_genome | 19 +
bin/create_pan_genome_plots.R | 59 +
bin/extract_proteome_from_gff | 19 +
bin/iterative_cdhit | 19 +
bin/pan_genome_assembly_statistics | 19 +
bin/pan_genome_core_alignment | 19 +
bin/pan_genome_post_analysis | 19 +
bin/pan_genome_reorder_spreadsheet | 19 +
bin/parallel_all_against_all_blastp | 19 +
bin/protein_alignment_from_nucleotides | 19 +
bin/query_pan_genome | 19 +
bin/roary | 19 +
bin/transfer_annotation_to_groups | 19 +
deployment_process | 7 +
dist.ini | 32 +
install_dependencies.sh | 248 +++
lib/Bio/Roary.pm | 146 ++
lib/Bio/Roary/AccessoryBinaryFasta.pm | 100 +
lib/Bio/Roary/AccessoryClustering.pm | 95 +
lib/Bio/Roary/AnalyseGroups.pm | 119 ++
lib/Bio/Roary/AnnotateGroups.pm | 356 ++++
lib/Bio/Roary/AssemblyStatistics.pm | 207 ++
lib/Bio/Roary/BedFromGFFRole.pm | 71 +
lib/Bio/Roary/ChunkFastaFile.pm | 77 +
lib/Bio/Roary/ClustersRole.pm | 70 +
lib/Bio/Roary/CombinedProteome.pm | 51 +
lib/Bio/Roary/CommandLine/AssemblyStatistics.pm | 134 ++
lib/Bio/Roary/CommandLine/Common.pm | 57 +
lib/Bio/Roary/CommandLine/CreatePanGenome.pm | 72 +
.../Roary/CommandLine/ExtractProteomeFromGff.pm | 121 ++
.../CommandLine/GeneAlignmentFromNucleotides.pm | 134 ++
lib/Bio/Roary/CommandLine/IterativeCdhit.pm | 119 ++
.../CommandLine/ParallelAllAgainstAllBlastp.pm | 141 ++
lib/Bio/Roary/CommandLine/QueryRoary.pm | 253 +++
lib/Bio/Roary/CommandLine/Roary.pm | 356 ++++
lib/Bio/Roary/CommandLine/RoaryCoreAlignment.pm | 143 ++
lib/Bio/Roary/CommandLine/RoaryPostAnalysis.pm | 237 +++
.../Roary/CommandLine/RoaryReorderSpreadsheet.pm | 100 +
.../CommandLine/TransferAnnotationToGroups.pm | 108 +
lib/Bio/Roary/ContigsToGeneIDsFromGFF.pm | 145 ++
lib/Bio/Roary/Exceptions.pm | 16 +
lib/Bio/Roary/External/Blastp.pm | 68 +
lib/Bio/Roary/External/Cdhit.pm | 103 +
lib/Bio/Roary/External/CheckTools.pm | 190 ++
lib/Bio/Roary/External/Fasttree.pm | 73 +
.../Roary/External/GeneAlignmentFromNucleotides.pm | 138 ++
lib/Bio/Roary/External/IterativeCdhit.pm | 92 +
lib/Bio/Roary/External/Mafft.pm | 76 +
lib/Bio/Roary/External/Makeblastdb.pm | 72 +
lib/Bio/Roary/External/Mcl.pm | 106 +
lib/Bio/Roary/External/PostAnalysis.pm | 187 ++
lib/Bio/Roary/External/Prank.pm | 77 +
lib/Bio/Roary/ExtractCoreGenesFromSpreadsheet.pm | 170 ++
lib/Bio/Roary/ExtractProteomeFromGFF.pm | 197 ++
lib/Bio/Roary/ExtractProteomeFromGFFs.pm | 80 +
lib/Bio/Roary/FilterFullClusters.pm | 144 ++
lib/Bio/Roary/FilterUnknownsFromFasta.pm | 88 +
lib/Bio/Roary/GeneNamesFromGFF.pm | 73 +
lib/Bio/Roary/GroupLabels.pm | 62 +
lib/Bio/Roary/GroupStatistics.pm | 242 +++
lib/Bio/Roary/InflateClusters.pm | 109 +
lib/Bio/Roary/IterativeCdhit.pm | 114 +
lib/Bio/Roary/JobRunner/Local.pm | 64 +
lib/Bio/Roary/JobRunner/Parallel.pm | 69 +
lib/Bio/Roary/JobRunner/Role.pm | 65 +
lib/Bio/Roary/LookupGeneFiles.pm | 53 +
lib/Bio/Roary/MergeMultifastaAlignments.pm | 121 ++
lib/Bio/Roary/OrderGenes.pm | 391 ++++
lib/Bio/Roary/Output/BlastIdentityFrequency.pm | 62 +
.../Output/CoreGeneAlignmentCoordinatesEMBL.pm | 81 +
lib/Bio/Roary/Output/DifferenceBetweenSets.pm | 126 ++
lib/Bio/Roary/Output/EMBLHeaderCommon.pm | 41 +
lib/Bio/Roary/Output/EmblGroups.pm | 246 +++
lib/Bio/Roary/Output/GroupMultifasta.pm | 69 +
lib/Bio/Roary/Output/GroupsMultifastaNucleotide.pm | 166 ++
lib/Bio/Roary/Output/GroupsMultifastaProtein.pm | 68 +
lib/Bio/Roary/Output/GroupsMultifastas.pm | 46 +
.../Roary/Output/GroupsMultifastasNucleotide.pm | 86 +
lib/Bio/Roary/Output/NumberOfGroups.pm | 121 ++
lib/Bio/Roary/Output/QueryGroups.pm | 139 ++
lib/Bio/Roary/ParallelAllAgainstAllBlast.pm | 143 ++
lib/Bio/Roary/ParseGFFAnnotationRole.pm | 32 +
lib/Bio/Roary/PostAnalysis.pm | 353 ++++
lib/Bio/Roary/PrepareInputFiles.pm | 116 ++
lib/Bio/Roary/PresenceAbsenceMatrix.pm | 84 +
lib/Bio/Roary/QC/Report.pm | 241 +++
lib/Bio/Roary/ReformatInputGFFs.pm | 162 ++
lib/Bio/Roary/ReorderSpreadsheet.pm | 133 ++
lib/Bio/Roary/SampleOrder.pm | 50 +
lib/Bio/Roary/SequenceLengths.pm | 43 +
lib/Bio/Roary/SortFasta.pm | 127 ++
lib/Bio/Roary/SplitGroups.pm | 324 +++
lib/Bio/Roary/SpreadsheetRole.pm | 66 +
t/00_requires_external.t | 20 +
t/Bio/Roary/AccessoryBinaryFasta.t | 72 +
t/Bio/Roary/AccessoryClustering.t | 104 +
t/Bio/Roary/AnalyseGroups.t | 70 +
t/Bio/Roary/AnnotateGroups.t | 102 +
t/Bio/Roary/AssemblyStatistics.t | 121 ++
t/Bio/Roary/ChunkFastaFile.t | 41 +
t/Bio/Roary/CombinedProteome.t | 39 +
t/Bio/Roary/CommandLine/ExtractProteomeFromGff.t | 28 +
.../CommandLine/GeneAlignmentFromNucleotides.t | 41 +
.../CommandLine/ParallelAllAgainstAllBlastp.t | 29 +
t/Bio/Roary/CommandLine/QueryRoary.t | 71 +
t/Bio/Roary/CommandLine/Roary.t | 322 +++
t/Bio/Roary/CommandLine/RoaryCoreAlignment.t | 27 +
t/Bio/Roary/CommandLine/RoaryPostAnalysis.t | 108 +
t/Bio/Roary/CommandLine/RoaryReorderSpreadsheet.t | 52 +
.../Roary/CommandLine/TransferAnnotationToGroups.t | 26 +
t/Bio/Roary/ContigsToGeneIDsFromGFF.t | 76 +
t/Bio/Roary/EmblGroups.t | 47 +
t/Bio/Roary/External/Blastp.t | 44 +
t/Bio/Roary/External/Cdhit.t | 39 +
t/Bio/Roary/External/CheckTools.t | 23 +
t/Bio/Roary/External/Mafft.t | 43 +
t/Bio/Roary/External/Makeblastdb.t | 32 +
t/Bio/Roary/External/Mcl.t | 54 +
t/Bio/Roary/External/Prank.t | 44 +
t/Bio/Roary/ExtractCoreGenesFromSpreadsheet.t | 33 +
t/Bio/Roary/ExtractProteomeFromGFFs.t | 82 +
t/Bio/Roary/FilterFullClusters.t | 36 +
t/Bio/Roary/GeneNamesFromGFF.t | 94 +
t/Bio/Roary/GroupLabels.t | 25 +
t/Bio/Roary/GroupStatistics.t | 79 +
t/Bio/Roary/InflateClusters.t | 40 +
t/Bio/Roary/OrderGenes.t | 148 ++
.../Output/CoreGeneAlignmentCoorindatesEMBL.t | 42 +
t/Bio/Roary/Output/DifferenceBetweenSets.t | 38 +
t/Bio/Roary/Output/GroupsMultifastaProtein.t | 26 +
t/Bio/Roary/Output/GroupsMultifastas.t | 45 +
t/Bio/Roary/Output/GroupsMultifastasNucleotide.t | 91 +
t/Bio/Roary/Output/NumberOfGroups.t | 71 +
t/Bio/Roary/Output/QueryGroups.t | 73 +
t/Bio/Roary/ParallelAllAgainstAllBlast.t | 30 +
t/Bio/Roary/PrepareInputFiles.t | 56 +
t/Bio/Roary/PresenceAbsenceMatrix.t | 97 +
t/Bio/Roary/QC/Report.t | 100 +
t/Bio/Roary/ReformatInputGFFs.t | 69 +
t/Bio/Roary/ReorderSpreadsheet.t | 36 +
t/Bio/Roary/SampleOrder.t | 164 ++
t/Bio/Roary/SequenceLengths.t | 34 +
t/Bio/Roary/SortFasta.t | 58 +
t/Bio/Roary/SplitGroups.t | 70 +
t/bin/dummy_blastp | 16 +
t/bin/dummy_cd-hit | 5 +
t/bin/dummy_makeblastdb | 18 +
t/bin/dummy_mcl | 12 +
t/bin/dummy_mcxdeblast | 2 +
t/bin/dummy_segmasker | 15 +
t/data/accessory_graphs/core_deletion | 8 +
t/data/accessory_graphs/core_island | 8 +
t/data/accessory_graphs/file_1.fa | 54 +
t/data/accessory_graphs/file_1.gff | 36 +
t/data/accessory_graphs/file_2.fa | 36 +
t/data/accessory_graphs/file_2.gff | 27 +
t/data/accessory_graphs/file_3.fa | 36 +
t/data/accessory_graphs/file_3.gff | 27 +
t/data/accessory_graphs/no_accessory | 3 +
t/data/accessory_graphs/one_branch | 5 +
t/data/accessory_graphs/one_bubble | 6 +
t/data/accessory_graphs/single_gene_contig | 1 +
t/data/accessory_graphs/two_graphs | 4 +
t/data/blast_results | 13 +
t/data/clustered_proteins | 12 +
t/data/clustered_proteins_pan_genome | 21 +
t/data/clustered_proteins_post_analysis | 13 +
t/data/clusters_input.fa | 20 +
t/data/clusters_to_inflate | 40 +
t/data/clusters_to_inflate.mcl | 4 +
t/data/clusters_to_inflate_original_input.fa | 60 +
t/data/clustersfile | 33 +
t/data/core_alignment.csv | 4 +
t/data/core_alignment/argF.fa.aln | 4 +
t/data/core_alignment/hly.fa.aln | 4 +
t/data/core_alignment/speH.fa.aln | 4 +
t/data/core_alignment_core0.66.csv | 4 +
.../expected_core_gene_alignment.aln | 45 +
t/data/core_alignment_gene_lookup/query_1.gff | 29 +
t/data/core_alignment_gene_lookup/query_2.gff | 29 +
t/data/core_alignment_gene_lookup/query_3.gff | 29 +
t/data/core_group_statistics.csv | 11 +
t/data/empty_file | 0
t/data/example_1.faa | 29 +
t/data/example_2.faa | 27 +
t/data/example_3.faa | 43 +
t/data/example_annotation.gff | 271 +++
.../example_annotation.gff.proteome.faa.expected | 75 +
t/data/example_annotation_2.gff | 271 +++
t/data/example_groups | 6 +
t/data/example_groups_without_labels | 6 +
t/data/exp_qc_report.csv | 4 +
t/data/exp_qc_report_real.csv | 3 +
t/data/expected_0.seq | 4 +
t/data/expected_5.seq | 6 +
t/data/expected_accessory_binary_genes.fa | 8 +
t/data/expected_accessory_binary_genes_bounded.fa | 8 +
t/data/expected_clustered_proteins | 9 +
t/data/expected_clusters_to_inflate | 4 +
t/data/expected_combined_proteome.fa | 56 +
.../expected_combined_proteome_with_filtering.fa | 82 +
t/data/expected_complement_of_groups.gg | 6 +
t/data/expected_complement_of_groups_core0.66.gg | 3 +
t/data/expected_core_60_summary_statistics.txt | 5 +
t/data/expected_core_gene_alignment.aln | 4 +
t/data/expected_core_gene_alignment_core0.66.aln | 6 +
t/data/expected_create_pan_genome.fa | 56 +
t/data/expected_example_annotation_1.faa | 30 +
t/data/expected_filtered_original_input.fa | 48 +
t/data/expected_g2_g5_pan_genome_reference.fa | 70 +
t/data/expected_gene_presence_and_absence.Rtab | 8 +
...ed_gff_set_difference_common_set_statistics.csv | 4 +
t/data/expected_group_labels | 6 +
t/data/expected_group_statitics.csv | 8 +
t/data/expected_group_statitics_missing_genes.csv | 8 +
t/data/expected_group_statitics_verbose.csv | 8 +
t/data/expected_inflated_results | 5 +
t/data/expected_intersection_of_groups.gg | 1 +
t/data/expected_intersection_of_groups_core0.66.gg | 4 +
t/data/expected_intersection_of_groups_paralogs.gg | 2 +
t/data/expected_mafft_input.fa.aln | 66 +
...xpected_mafft_real_data_core_gene_alignment.aln | 2170 ++++++++++++++++++++
t/data/expected_nnn_at_end.fa | 8 +
t/data/expected_nuc_multifasta.fa.aln | 90 +
t/data/expected_nuc_multifasta.faa | 48 +
t/data/expected_nuc_multifasta_mafft.fa.aln | 90 +
t/data/expected_number_of_conserved_genes.tab | 10 +
t/data/expected_number_of_conserved_genes_0.6.tab | 10 +
t/data/expected_number_of_genes_in_pan_genome.tab | 10 +
t/data/expected_number_of_new_genes.tab | 10 +
t/data/expected_number_of_unique_genes.tab | 10 +
t/data/expected_one_gene_presence_and_absence.Rtab | 2 +
t/data/expected_out_of_order_fasta.fa.sorted.fa | 10 +
t/data/expected_output_core_missing_genes.aln | 10 +
t/data/expected_output_filtered.fa | 18 +
t/data/expected_output_groups | 2 +
t/data/expected_output_groups_cdhit | 1 +
t/data/expected_output_groups_group_2.fa | 19 +
t/data/expected_output_groups_group_2_multi.fa | 19 +
t/data/expected_output_groups_group_5.fa | 9 +
t/data/expected_output_groups_group_5_multi.fa | 9 +
t/data/expected_output_merged.aln | 8 +
t/data/expected_output_merged_sparse.aln | 8 +
t/data/expected_pan_genome.fa | 33 +
t/data/expected_pan_genome_one_gene_per_fasta.fa | 33 +
t/data/expected_pan_genome_reference.fa | 1466 +++++++++++++
t/data/expected_prank_input.fa.aln | 66 +
t/data/expected_query_1.fna | 252 +++
t/data/expected_query_2.fna | 252 +++
t/data/expected_real_data_core_gene_alignment.aln | 2168 +++++++++++++++++++
t/data/expected_reannotated_groups_file | 7 +
t/data/expected_sample_weights_accessory_graph.dot | 15 +
...xpected_sample_weights_core_accessory_graph.dot | 22 +
t/data/expected_set_difference_common_set | 3 +
...pected_set_difference_common_set_statistics.csv | 4 +
t/data/expected_set_difference_unique_set_one | 1 +
...ed_set_difference_unique_set_one_statistics.csv | 2 +
t/data/expected_set_difference_unique_set_two | 3 +
...ed_set_difference_unique_set_two_statistics.csv | 4 +
t/data/expected_some_different_output | 95 +
t/data/expected_summary_statistics.txt | 5 +
t/data/expected_uneven_sequences.fa | 18 +
t/data/expected_union_of_groups.gg | 7 +
t/data/genbank_gbff/genbank1.gff | 195 ++
.../genbank1.gff.proteome.faa.expected | 49 +
t/data/genbank_gbff/genbank2.gff | 282 +++
.../genbank2.gff.proteome.faa.expected | 26 +
t/data/genbank_gbff/genbank3.gff | 282 +++
.../genbank3.gff.proteome.faa.expected | 26 +
.../genbank_gbff/genbank_gene_presence_absence.csv | 12 +
t/data/gene_category_count.csv | 1 +
t/data/group_1.fa.aln | 84 +
t/data/group_9.fa | 15 +
t/data/input_accessory_binary.fa | 20 +
t/data/input_block_spreadsheet.csv | 52 +
t/data/kraken_report.txt | 19 +
t/data/kraken_test/database.idx | Bin 0 -> 8208 bytes
t/data/kraken_test/database.jdb | Bin 0 -> 2872 bytes
t/data/kraken_test/database.kdb | Bin 0 -> 2872 bytes
t/data/kraken_test/taxonomy/names.dmp | 77 +
t/data/kraken_test/taxonomy/nodes.dmp | 12 +
t/data/large_accessory_binary_genes.fa | 94 +
t/data/locus_tag_gffs/query_1.gff | 271 +++
.../query_1.gff.proteome.faa.expected | 75 +
t/data/locus_tag_gffs/query_2.gff | 271 +++
.../query_2.gff.proteome.faa.expected | 75 +
t/data/locus_tag_gffs/query_3.gff | 271 +++
.../query_3.gff.proteome.faa.expected | 75 +
t/data/locus_tag_gffs/query_5.gff | 271 +++
.../query_5.gff.proteome.faa.expected | 75 +
t/data/mafft_input.fa | 59 +
t/data/mcl_file | 5 +
t/data/mdoH.fa.aln | 88 +
t/data/mdoH_mafft.fa.aln | 88 +
t/data/multfasta1.aln | 8 +
t/data/multfasta2.aln | 8 +
t/data/multfasta3.aln | 8 +
t/data/multfasta4.aln | 7 +
t/data/multfasta5.aln | 7 +
t/data/multifasta_files/expected_output.embl | 19 +
t/data/nnn_at_end.fa | 8 +
t/data/nnn_at_end.fa.sorted.fa | 8 +
t/data/nuc_multifasta.fa | 112 +
t/data/nuc_to_be_aligned.fa | 90 +
t/data/out_of_order_fasta.fa | 10 +
t/data/out_of_order_fasta.fa.sorted.fa | 10 +
t/data/overall_gene_presence_absence.csv | 22 +
t/data/pan_genome_sequences/argF.fa | 36 +
t/data/pan_genome_sequences/hly.fa | 51 +
t/data/pan_genome_sequences/speH.fa | 28 +
t/data/post_analysis/_clustered.clstr | 55 +
t/data/post_analysis/_combined_files | 169 ++
t/data/post_analysis/_combined_files.groups | 0
t/data/post_analysis/_fasta_files | 3 +
t/data/post_analysis/_gff_files | 3 +
t/data/post_analysis/_uninflated_mcl_groups | 0
t/data/post_analysis/query_1.gff.proteome.faa | 75 +
t/data/post_analysis/query_2.gff.proteome.faa | 75 +
t/data/post_analysis/query_6.gff.proteome.faa | 19 +
.../post_analysis_expected/accessory.header.embl | 7 +
t/data/post_analysis_expected/accessory.tab | 0
.../core_accessory.header.embl | 55 +
t/data/post_analysis_expected/core_accessory.tab | 48 +
.../gene_presence_absence.csv | 14 +
t/data/prank_input.fa | 59 +
t/data/proteome_with_and_without_descriptions.faa | 29 +
t/data/query_1.fa | 8 +
t/data/query_1.gff | 271 +++
t/data/query_1_alternative_patterns.gff | 262 +++
t/data/query_2.fa | 8 +
t/data/query_2.gff | 271 +++
t/data/query_3.fa | 8 +
t/data/query_3.gff | 271 +++
t/data/query_4_missing_genes.fa | 2 +
t/data/query_4_missing_genes.gff | 256 +++
t/data/query_5.gff | 271 +++
t/data/query_6.gff | 271 +++
t/data/query_groups | 7 +
t/data/query_groups_all_merged | 1 +
t/data/query_groups_missing_genes | 7 +
t/data/query_groups_paralogs | 6 +
t/data/query_groups_reference | 6 +
t/data/raxml.tre | 1 +
t/data/real_data_1.gff | 1641 +++++++++++++++
t/data/real_data_2.gff | 1641 +++++++++++++++
t/data/real_data_core_gene_alignment.aln | 1950 ++++++++++++++++++
.../reformat_input_gffs/expected_fixed_query_2.gff | 220 ++
.../reformat_input_gffs/expected_fixed_query_3.gff | 220 ++
t/data/reformat_input_gffs/expected_real_1.gff | 223 ++
t/data/reformat_input_gffs/query_1.gff | 220 ++
t/data/reformat_input_gffs/query_2.gff | 220 ++
t/data/reformat_input_gffs/query_3.gff | 220 ++
t/data/reformat_input_gffs/real_1.gff | 223 ++
t/data/reorder_isolates.tre | 1 +
t/data/reorder_isolates_expected_output.csv | 8 +
...rder_isolates_expected_output_breadth_alpha.csv | 8 +
...r_isolates_expected_output_breadth_creation.csv | 8 +
...der_isolates_expected_output_breadth_height.csv | 8 +
...r_isolates_expected_output_breadth_revalpha.csv | 8 +
...eorder_isolates_expected_output_depth_alpha.csv | 8 +
...der_isolates_expected_output_depth_creation.csv | 8 +
...order_isolates_expected_output_depth_height.csv | 8 +
...der_isolates_expected_output_depth_revalpha.csv | 8 +
t/data/reorder_isolates_input.csv | 8 +
t/data/sequences_with_unknowns.faa | 26 +
t/data/shred1.gff | 9 +
t/data/shred1.shred.fa | 16 +
t/data/shred2.gff | 9 +
t/data/shred2.shred.fa | 16 +
t/data/sopB.fa.aln | 60 +
t/data/speH.fa.aln | 32 +
t/data/split_groups/paralog_clusters1 | 13 +
t/data/split_groups/paralog_clusters2 | 11 +
t/data/split_groups/paralog_clusters3 | 13 +
t/data/split_groups/paralog_clusters4 | 14 +
t/data/split_groups/paralog_exp_clusters1 | 14 +
t/data/split_groups/paralog_exp_clusters2 | 12 +
t/data/split_groups/paralog_exp_clusters3 | 15 +
t/data/split_groups/paralog_exp_clusters4 | 17 +
t/data/split_groups/paralogs1.fa | 50 +
t/data/split_groups/paralogs2.fa | 50 +
t/data/split_groups/paralogs3.fa | 50 +
t/data/split_pan_genome_sequences/argF.fa | 36 +
t/data/split_pan_genome_sequences/different.fa | 38 +
t/data/split_pan_genome_sequences/hly.fa | 34 +
.../reannotated_groups_file | 4 +
t/data/split_pan_genome_sequences/speH.fa | 28 +
t/data/uneven_sequences.fa | 18 +
t/data/uneven_sequences.fa.sorted.fa | 18 +
t/data/variable_core/gene_1.fa.aln | 10 +
t/data/variable_core/gene_2.fa.aln | 8 +
t/data/variable_core/gene_3.fa.aln | 8 +
t/data/variable_core/gene_4.fa.aln | 4 +
t/data/variable_core/gene_5.fa.aln | 10 +
t/dummy_blastp | 3 +
t/dummy_cd-hit | 5 +
t/dummy_makeblastdb | 5 +
t/lib/TestHelper.pm | 323 +++
403 files changed, 37165 insertions(+)
diff --git a/.gitignore b/.gitignore
new file mode 100644
index 0000000..5a1d3b0
--- /dev/null
+++ b/.gitignore
@@ -0,0 +1,36 @@
+.DS_Store
+blib/
+.build/
+_build/
+cover_db/
+inc/
+Build
+!Build/
+Build.bat
+.last_cover_stats
+Makefile
+Makefile.old
+MANIFEST.bak
+META.yml
+MYMETA.yml
+nytprof.out
+pm_to_blib
+_clustered
+_clustered.bak.clstr
+example_1.faa.tmp.filtered.fa
+example_2.faa.tmp.filtered.fa
+pan_genome.fa
+query_1.fa.tmp.filtered.fa
+query_2.fa.tmp.filtered.fa
+query_3.fa.tmp.filtered.fa
+accessory.header.embl
+blast_identity_frequency.Rtab
+core_accessory.header.embl
+reannotated_groups_file
+set_difference_common_set_reannotated
+set_difference_unique_set_one_reannotated
+set_difference_unique_set_two_reannotated
+extras/
+bin/shred_assemblies
+Bio-Roary-*
+Roary-*
diff --git a/.travis.yml b/.travis.yml
new file mode 100644
index 0000000..e7d60b1
--- /dev/null
+++ b/.travis.yml
@@ -0,0 +1,29 @@
+language: perl
+sudo: false
+addons:
+ apt:
+ packages:
+ - libssl-dev
+ - mafft
+cache:
+ directories:
+ - build/parallel-20150522
+ - build/parallel-20141022
+ - build/parallel-20130922
+ - build/bedtools2
+ - build/cd-hit-v4.6.3-2015-0515
+ - build/prank-msa-master
+ - build/ncbi-blast-2.2.30+
+ - build/mcl-14-137
+ - build/fasttree
+perl:
+ - "5.10"
+ - "5.14"
+ - "5.20"
+env:
+ - PARALLEL_VERSION=20150522
+ - PARALLEL_VERSION=20141022
+ - PARALLEL_VERSION=20130922
+install:
+ - "source ./install_dependencies.sh"
+script: "dzil test"
diff --git a/AUTHORS b/AUTHORS
new file mode 100644
index 0000000..f9d4e15
--- /dev/null
+++ b/AUTHORS
@@ -0,0 +1,2 @@
+Andrew J. Page (ap13 at sanger.ac.uk)
+Carla A. Cummins (cc21 at sanger.ac.uk)
diff --git a/GPL-LICENSE b/GPL-LICENSE
new file mode 100644
index 0000000..3f03f8b
--- /dev/null
+++ b/GPL-LICENSE
@@ -0,0 +1,680 @@
+This software is Copyright (c) 2013 by Wellcome Trust Sanger Institute.
+
+This is free software, licensed under:
+
+ The GNU General Public License, Version 3, June 2007
+
+ GNU GENERAL PUBLIC LICENSE
+ Version 3, 29 June 2007
+
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+
+ 15. Disclaimer of Warranty.
+
+ THERE IS NO WARRANTY FOR THE PROGRAM, TO THE EXTENT PERMITTED BY
+APPLICABLE LAW. EXCEPT WHEN OTHERWISE STATED IN WRITING THE COPYRIGHT
+HOLDERS AND/OR OTHER PARTIES PROVIDE THE PROGRAM "AS IS" WITHOUT WARRANTY
+OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING, BUT NOT LIMITED TO,
+THE IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR
+PURPOSE. THE ENTIRE RISK AS TO THE QUALITY AND PERFORMANCE OF THE PROGRAM
+IS WITH YOU. SHOULD THE PROGRAM PROVE DEFECTIVE, YOU ASSUME THE COST OF
+ALL NECESSARY SERVICING, REPAIR OR CORRECTION.
+
+ 16. Limitation of Liability.
+
+ IN NO EVENT UNLESS REQUIRED BY APPLICABLE LAW OR AGREED TO IN WRITING
+WILL ANY COPYRIGHT HOLDER, OR ANY OTHER PARTY WHO MODIFIES AND/OR CONVEYS
+THE PROGRAM AS PERMITTED ABOVE, BE LIABLE TO YOU FOR DAMAGES, INCLUDING ANY
+GENERAL, SPECIAL, INCIDENTAL OR CONSEQUENTIAL DAMAGES ARISING OUT OF THE
+USE OR INABILITY TO USE THE PROGRAM (INCLUDING BUT NOT LIMITED TO LOSS OF
+DATA OR DATA BEING RENDERED INACCURATE OR LOSSES SUSTAINED BY YOU OR THIRD
+PARTIES OR A FAILURE OF THE PROGRAM TO OPERATE WITH ANY OTHER PROGRAMS),
+EVEN IF SUCH HOLDER OR OTHER PARTY HAS BEEN ADVISED OF THE POSSIBILITY OF
+SUCH DAMAGES.
+
+ 17. Interpretation of Sections 15 and 16.
+
+ If the disclaimer of warranty and limitation of liability provided
+above cannot be given local legal effect according to their terms,
+reviewing courts shall apply local law that most closely approximates
+an absolute waiver of all civil liability in connection with the
+Program, unless a warranty or assumption of liability accompanies a
+copy of the Program in return for a fee.
+
+ END OF TERMS AND CONDITIONS
+
+ How to Apply These Terms to Your New Programs
+
+ If you develop a new program, and you want it to be of the greatest
+possible use to the public, the best way to achieve this is to make it
+free software which everyone can redistribute and change under these terms.
+
+ To do so, attach the following notices to the program. It is safest
+to attach them to the start of each source file to most effectively
+state the exclusion of warranty; and each file should have at least
+the "copyright" line and a pointer to where the full notice is found.
+
+ <one line to give the program's name and a brief idea of what it does.>
+ Copyright (C) <year> <name of author>
+
+ This program is free software: you can redistribute it and/or modify
+ it under the terms of the GNU General Public License as published by
+ the Free Software Foundation, either version 3 of the License, or
+ (at your option) any later version.
+
+ This program is distributed in the hope that it will be useful,
+ but WITHOUT ANY WARRANTY; without even the implied warranty of
+ MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
+ GNU General Public License for more details.
+
+ You should have received a copy of the GNU General Public License
+ along with this program. If not, see <http://www.gnu.org/licenses/>.
+
+Also add information on how to contact you by electronic and paper mail.
+
+ If the program does terminal interaction, make it output a short
+notice like this when it starts in an interactive mode:
+
+ <program> Copyright (C) <year> <name of author>
+ This program comes with ABSOLUTELY NO WARRANTY; for details type `show w'.
+ This is free software, and you are welcome to redistribute it
+ under certain conditions; type `show c' for details.
+
+The hypothetical commands `show w' and `show c' should show the appropriate
+parts of the General Public License. Of course, your program's commands
+might be different; for a GUI interface, you would use an "about box".
+
+ You should also get your employer (if you work as a programmer) or school,
+if any, to sign a "copyright disclaimer" for the program, if necessary.
+For more information on this, and how to apply and follow the GNU GPL, see
+<http://www.gnu.org/licenses/>.
+
+ The GNU General Public License does not permit incorporating your program
+into proprietary programs. If your program is a subroutine library, you
+may consider it more useful to permit linking proprietary applications with
+the library. If this is what you want to do, use the GNU Lesser General
+Public License instead of this License. But first, please read
+<http://www.gnu.org/philosophy/why-not-lgpl.html>.
diff --git a/README.md b/README.md
new file mode 100644
index 0000000..6c3ece6
--- /dev/null
+++ b/README.md
@@ -0,0 +1,92 @@
+#Roary the pan genome pipeline
+For instructions on how to use the software, the input format and output formats, please see [the Roary website](http://sanger-pathogens.github.io/Roary).
+
+[](https://travis-ci.org/sanger-pathogens/Roary)
+
+Roary is a high speed stand alone pan genome pipeline, which takes annotated assemblies in GFF3 format (produced by Prokka) and calculates the pan genome. Using a standard desktop PC, it can analyse datasets with thousands of samples, something which is computationally infeasible with existing methods, without compromising the quality of the results. 128 samples can be analysed in under 1 hour using 1 GB of RAM and a single processor. To perform this analysis using existing methods wou [...]
+
+##Citation
+ "Roary: Rapid large-scale prokaryote pan genome analysis",
+ Andrew J. Page, Carla A. Cummins, Martin Hunt, Vanessa K. Wong, Sandra Reuter, Matthew T. G. Holden, Maria Fookes, Daniel Falush, Jacqueline A. Keane, Julian Parkhill,
+ Bioinformatics, (2015). doi: http://dx.doi.org/10.1093/bioinformatics/btv421
+[Roary: Rapid large-scale prokaryote pan genome analysis](http://dx.doi.org/10.1093/bioinformatics/btv421)
+
+# Installation
+Theres are a number of dependancies required for Roary, with instructions specific to the type of system you have:
+* Ubuntu/Debian
+* CentOS/RedHat
+* Homebrew/Linuxbrew - OSX/Linux
+* Installing from source - OSX/Linux
+* Virtual Machine - OSX/Linux/Windows
+
+If the installation fails please contact your system administrator. If you encounter a bug please let us know by emailing roary at sanger.ac.uk .
+
+##Ubuntu/Debian
+All the dependancies can be installed using apt and cpanm (tested on Ubuntu 14.04). Root permissions are required.
+
+```
+sudo apt-get install bedtools cd-hit ncbi-blast+ mcl parallel cpanminus prank mafft fasttree
+sudo cpanm -f Bio::Roary
+```
+
+###Ubuntu 12.04
+Some of the software versions in apt are quite old so follow the instructions for [LinuxBrew](http://brew.sh/linuxbrew/) below.
+
+##CentOS/RedHat
+To install the dependancies, the easiest way is to install [LinuxBrew](http://brew.sh/linuxbrew/) using the steps for Fedora, then follow the steps below for installing Roary on LinuxBrew.
+
+##Homebrew/Linuxbrew - OSX/Linux
+Assuming you have [homebrew](http://brew.sh/) (OSX) or [linuxbrew](http://brew.sh/linuxbrew/) (Linux) setup and installed on your system:
+
+```
+brew tap homebrew/science
+brew install bedtools cd-hit blast mcl parallel prank mafft fasttree cpanm
+sudo cpanm -f Bio::Roary
+```
+
+##Virtual Machine - OSX/Linux/Windows
+Roary wont run natively on Windows but we have created virtual machine which has all of the software setup, including Prokka, along with the test datasets from the paper. It is based on [Bio-Linux 8](http://environmentalomics.org/bio-linux/). You need to first install [VirtualBox](https://www.virtualbox.org/), then load the virtual machine, using the 'File -> Import Appliance' menu option. The root password is 'manager'.
+
+ftp://ftp.sanger.ac.uk/pub/pathogens/pathogens-vm/pathogens-vm.latest.ova
+
+More importantly though, if your trying to do bioinformatics on Windows, your not going to get very far and you should seriously consider upgrading to Linux.
+
+##Installing from source (advanced Linux users only)
+As a last resort you can install everything from source. This is for users with advanced Linux skills and we do not provide any support with this method since you have the skills to figure things out.
+Download the latest software from (https://github.com/sanger-pathogens/Roary/tarball/master).
+
+Choose somewhere to put it, for example in your home directory (no root access required):
+
+```
+cd $HOME
+tar zxvf sanger-pathogens-Roary-xxxxxx.tar.gz
+ls Roary-*
+```
+
+Add the following lines to your $HOME/.bashrc file, or to /etc/profile.d/roary.sh to make it available to all users:
+
+```
+export PATH=$PATH:$HOME/Roary-x.x.x/bin
+export PERL5LIB=$PERL5LIB:$HOME/Roary-x.x.x/lib
+```
+Install the perl dependancies:
+
+```
+sudo cpanm Array::Utils Bio::Perl Exception::Class File::Basename File::Copy File::Find::Rule File::Grep File::Path File::Slurper File::Spec File::Temp File::Which FindBin Getopt::Long Graph Graph::Writer::Dot List::Util Log::Log4perl Moose Moose::Role Text::CSV PerlIO::utf8_strict
+```
+Install the external dependances either from source or from your packaging system:
+```
+bedtools cd-hit blast mcl GNUparallel prank mafft fasttree
+```
+
+## Ancient systems and versions of perl
+The code will not work with perl 5.8 or below (pre-modern perl). If your running a very old verison of Linux, your also in trouble.
+
+#Versions of software we test against
+* Perl 5.10, 5.14, 5.16, 5.18, 5.20
+* cdhit 4.6.1
+* ncbi blast+ 2.2.30
+* mcl 14-137
+* bedtools 2.20.1
+* prank 130410
+* GNU parallel 20130922, 20141022, 20150122
diff --git a/bin/create_pan_genome b/bin/create_pan_genome
new file mode 100755
index 0000000..0382093
--- /dev/null
+++ b/bin/create_pan_genome
@@ -0,0 +1,19 @@
+#!/usr/bin/env perl
+
+package Bio::Roary::Main::CreatePanGenome;
+
+# ABSTRACT: Create a pan genome from a set of GFF files with WTSI defaults
+# PODNAME: create_pan_genome
+
+=head1 SYNOPSIS
+
+Create a pan genome from a set of GFF files with WTSI defaults
+
+=cut
+
+use Cwd qw(abs_path);
+BEGIN { unshift( @INC, abs_path('./lib') ) }
+BEGIN { unshift( @INC, abs_path('./t/lib') ) }
+use Bio::Roary::CommandLine::CreatePanGenome;
+
+Bio::Roary::CommandLine::CreatePanGenome->new(args => \@ARGV, script_name => $0)->run;
diff --git a/bin/create_pan_genome_plots.R b/bin/create_pan_genome_plots.R
new file mode 100755
index 0000000..8bf392e
--- /dev/null
+++ b/bin/create_pan_genome_plots.R
@@ -0,0 +1,59 @@
+#!/usr/bin/env Rscript
+# ABSTRACT: Create R plots
+# PODNAME: create_plots.R
+# Take the output files from the pan genome pipeline and create nice plots.
+library(ggplot2)
+
+
+mydata = read.table("number_of_new_genes.Rtab")
+boxplot(mydata, data=mydata, main="Number of new genes",
+ xlab="No. of genomes", ylab="No. of genes",varwidth=TRUE, ylim=c(0,max(mydata)), outline=FALSE)
+
+mydata = read.table("number_of_conserved_genes.Rtab")
+boxplot(mydata, data=mydata, main="Number of conserved genes",
+ xlab="No. of genomes", ylab="No. of genes",varwidth=TRUE, ylim=c(0,max(mydata)), outline=FALSE)
+
+mydata = read.table("number_of_genes_in_pan_genome.Rtab")
+boxplot(mydata, data=mydata, main="No. of genes in the pan-genome",
+ xlab="No. of genomes", ylab="No. of genes",varwidth=TRUE, ylim=c(0,max(mydata)), outline=FALSE)
+
+mydata = read.table("number_of_unique_genes.Rtab")
+boxplot(mydata, data=mydata, main="Number of unique genes",
+ xlab="No. of genomes", ylab="No. of genes",varwidth=TRUE, ylim=c(0,max(mydata)), outline=FALSE)
+
+mydata = read.table("blast_identity_frequency.Rtab")
+plot(mydata,main="Number of blastp hits with different percentage identity", xlab="Blast percentage identity", ylab="No. blast results")
+
+
+library(ggplot2)
+conserved = colMeans(read.table("number_of_conserved_genes.Rtab"))
+total = colMeans(read.table("number_of_genes_in_pan_genome.Rtab"))
+
+genes = data.frame( genes_to_genomes = c(conserved,total),
+ genomes = c(c(1:length(conserved)),c(1:length(conserved))),
+ Key = c(rep("Conserved genes",length(conserved)), rep("Total genes",length(total))) )
+
+ggplot(data = genes, aes(x = genomes, y = genes_to_genomes, group = Key, linetype=Key)) +geom_line()+
+theme_classic() +
+ylim(c(1,max(total)))+
+xlim(c(1,length(total)))+
+xlab("No. of genomes") +
+ylab("No. of genes")+ theme_bw(base_size = 16) + theme(legend.justification=c(0,1),legend.position=c(0,1))+
+ggsave(filename="conserved_vs_total_genes.png", scale=1)
+
+######################
+
+unique_genes = colMeans(read.table("number_of_unique_genes.Rtab"))
+new_genes = colMeans(read.table("number_of_new_genes.Rtab"))
+
+genes = data.frame( genes_to_genomes = c(unique_genes,new_genes),
+ genomes = c(c(1:length(unique_genes)),c(1:length(unique_genes))),
+ Key = c(rep("Unique genes",length(unique_genes)), rep("New genes",length(new_genes))) )
+
+ggplot(data = genes, aes(x = genomes, y = genes_to_genomes, group = Key, linetype=Key)) +geom_line()+
+theme_classic() +
+ylim(c(1,max(unique_genes)))+
+xlim(c(1,length(unique_genes)))+
+xlab("No. of genomes") +
+ylab("No. of genes")+ theme_bw(base_size = 16) + theme(legend.justification=c(1,1),legend.position=c(1,1))+
+ggsave(filename="unique_vs_new_genes.png", scale=1)
diff --git a/bin/extract_proteome_from_gff b/bin/extract_proteome_from_gff
new file mode 100755
index 0000000..54e9897
--- /dev/null
+++ b/bin/extract_proteome_from_gff
@@ -0,0 +1,19 @@
+#!/usr/bin/env perl
+
+package Bio::Roary::Main::ExtractProteomeFromGFF;
+
+# ABSTRACT: Take in GFF files and output the proteome
+# PODNAME: extract_proteome_from_gff
+
+=head1 SYNOPSIS
+
+Take in GFF files and output the proteome
+
+=cut
+
+use Cwd qw(abs_path);
+BEGIN { unshift( @INC, abs_path('./lib') ) }
+BEGIN { unshift( @INC, abs_path('./t/lib') ) }
+use Bio::Roary::CommandLine::ExtractProteomeFromGff;
+
+Bio::Roary::CommandLine::ExtractProteomeFromGff->new(args => \@ARGV, script_name => $0)->run;
diff --git a/bin/iterative_cdhit b/bin/iterative_cdhit
new file mode 100755
index 0000000..b90e31a
--- /dev/null
+++ b/bin/iterative_cdhit
@@ -0,0 +1,19 @@
+#!/usr/bin/env perl
+
+package Bio::Roary::Main::IterativeCdhit;
+
+# ABSTRACT: Iteratively run cdhit
+# PODNAME: iterative_cdhit
+
+=head1 SYNOPSIS
+
+Iteratively run cdhit
+
+=cut
+
+use Cwd qw(abs_path);
+BEGIN { unshift( @INC, abs_path('./lib') ) }
+BEGIN { unshift( @INC, abs_path('./t/lib') ) }
+use Bio::Roary::CommandLine::IterativeCdhit;
+
+Bio::Roary::CommandLine::IterativeCdhit->new(args => \@ARGV, script_name => $0)->run;
diff --git a/bin/pan_genome_assembly_statistics b/bin/pan_genome_assembly_statistics
new file mode 100755
index 0000000..5960b3e
--- /dev/null
+++ b/bin/pan_genome_assembly_statistics
@@ -0,0 +1,19 @@
+#!/usr/bin/env perl
+
+package Bio::Roary::Main::AssemblyStatistics;
+
+# ABSTRACT: Given a spreadsheet of gene presence and absense calculate some statistics
+# PODNAME: pan_genome_assembly_statistics
+
+=head1 SYNOPSIS
+
+Given a spreadsheet of gene presence and absense calculate some statistics
+
+=cut
+
+use Cwd qw(abs_path);
+BEGIN { unshift( @INC, abs_path('./lib') ) }
+BEGIN { unshift( @INC, abs_path('./t/lib') ) }
+use Bio::Roary::CommandLine::AssemblyStatistics;
+
+Bio::Roary::CommandLine::AssemblyStatistics->new(args => \@ARGV, script_name => $0)->run;
diff --git a/bin/pan_genome_core_alignment b/bin/pan_genome_core_alignment
new file mode 100755
index 0000000..5370331
--- /dev/null
+++ b/bin/pan_genome_core_alignment
@@ -0,0 +1,19 @@
+#!/usr/bin/env perl
+
+package Bio::Roary::Main::RoaryCoreAlignment;
+
+# ABSTRACT: Take in the group statistics spreadsheet and the location of the gene multifasta files and create a core alignment.
+# PODNAME: pan_genome_core_alignment
+
+=head1 SYNOPSIS
+
+ Take in the group statistics spreadsheet and the location of the gene multifasta files and create a core alignment.
+
+=cut
+
+use Cwd qw(abs_path);
+BEGIN { unshift( @INC, abs_path('./lib') ) }
+BEGIN { unshift( @INC, abs_path('./t/lib') ) }
+use Bio::Roary::CommandLine::RoaryCoreAlignment;
+
+Bio::Roary::CommandLine::RoaryCoreAlignment->new(args => \@ARGV, script_name => $0)->run;
diff --git a/bin/pan_genome_post_analysis b/bin/pan_genome_post_analysis
new file mode 100755
index 0000000..7fceb3f
--- /dev/null
+++ b/bin/pan_genome_post_analysis
@@ -0,0 +1,19 @@
+#!/usr/bin/env perl
+
+package Bio::Roary::Main::RoaryPostAnalysis;
+
+# ABSTRACT: Perform the post analysis on the pan genome
+# PODNAME: pan_genome_post_analysis
+
+=head1 SYNOPSIS
+
+Perform the post analysis on the pan genome
+
+=cut
+
+use Cwd qw(abs_path);
+BEGIN { unshift( @INC, abs_path('./lib') ) }
+BEGIN { unshift( @INC, abs_path('./t/lib') ) }
+use Bio::Roary::CommandLine::RoaryPostAnalysis;
+
+Bio::Roary::CommandLine::RoaryPostAnalysis->new(args => \@ARGV, script_name => $0)->run;
diff --git a/bin/pan_genome_reorder_spreadsheet b/bin/pan_genome_reorder_spreadsheet
new file mode 100755
index 0000000..f436248
--- /dev/null
+++ b/bin/pan_genome_reorder_spreadsheet
@@ -0,0 +1,19 @@
+#!/usr/bin/env perl
+
+package Bio::Roary::Main::RoaryReorderSpreadsheet;
+
+# ABSTRACT: Take in a tree and a spreadsheet and output a reordered spreadsheet
+# PODNAME: pan_genome_reorder_spreadsheet
+
+=head1 SYNOPSIS
+
+Take in a tree and a spreadsheet and output a reordered spreadsheet
+
+=cut
+
+use Cwd qw(abs_path);
+BEGIN { unshift( @INC, abs_path('./lib') ) }
+BEGIN { unshift( @INC, abs_path('./t/lib') ) }
+use Bio::Roary::CommandLine::RoaryReorderSpreadsheet;
+
+Bio::Roary::CommandLine::RoaryReorderSpreadsheet->new(args => \@ARGV, script_name => $0)->run;
diff --git a/bin/parallel_all_against_all_blastp b/bin/parallel_all_against_all_blastp
new file mode 100755
index 0000000..50cebc9
--- /dev/null
+++ b/bin/parallel_all_against_all_blastp
@@ -0,0 +1,19 @@
+#!/usr/bin/env perl
+
+package Bio::Roary::Main::ParallelAllAgainstAllBlastp;
+
+# ABSTRACT: Take in a FASTA file of proteins and blast against itself
+# PODNAME: parallel_all_against_all_blastp
+
+=head1 SYNOPSIS
+
+Take in a FASTA file of proteins and blast against itself
+
+=cut
+
+use Cwd qw(abs_path);
+BEGIN { unshift( @INC, abs_path('./lib') ) }
+BEGIN { unshift( @INC, abs_path('./t/lib') ) }
+use Bio::Roary::CommandLine::ParallelAllAgainstAllBlastp;
+
+Bio::Roary::CommandLine::ParallelAllAgainstAllBlastp->new(args => \@ARGV, script_name => $0)->run;
diff --git a/bin/protein_alignment_from_nucleotides b/bin/protein_alignment_from_nucleotides
new file mode 100755
index 0000000..b1f86f8
--- /dev/null
+++ b/bin/protein_alignment_from_nucleotides
@@ -0,0 +1,19 @@
+#!/usr/bin/env perl
+
+package Bio::Roary::Main::GeneAlignmentFromNucleotides;
+
+# ABSTRACT: Take in multi-FASTA files of nucleotides and align each file with PRANK or MAFFT
+# PODNAME: protein_alignment_from_nucleotides
+
+=head1 SYNOPSIS
+
+Take in multi-FASTA files of nucleotides and align each file with PRANK or MAFFT
+
+=cut
+
+use Cwd qw(abs_path);
+BEGIN { unshift( @INC, abs_path('./lib') ) }
+BEGIN { unshift( @INC, abs_path('./t/lib') ) }
+use Bio::Roary::CommandLine::GeneAlignmentFromNucleotides;
+
+Bio::Roary::CommandLine::GeneAlignmentFromNucleotides->new(args => \@ARGV, script_name => $0)->run;
diff --git a/bin/query_pan_genome b/bin/query_pan_genome
new file mode 100755
index 0000000..0e62826
--- /dev/null
+++ b/bin/query_pan_genome
@@ -0,0 +1,19 @@
+#!/usr/bin/env perl
+
+package Bio::Roary::Main::QueryRoary;
+
+# ABSTRACT: Take in a groups file and the protein fasta files and output selected data
+# PODNAME: query_pan_genome
+
+=head1 SYNOPSIS
+
+Take in a groups file and the protein fasta files and output selected data
+
+=cut
+
+use Cwd qw(abs_path);
+BEGIN { unshift( @INC, abs_path('./lib') ) }
+BEGIN { unshift( @INC, abs_path('./t/lib') ) }
+use Bio::Roary::CommandLine::QueryRoary;
+
+Bio::Roary::CommandLine::QueryRoary->new(args => \@ARGV, script_name => $0)->run;
diff --git a/bin/roary b/bin/roary
new file mode 100755
index 0000000..774341e
--- /dev/null
+++ b/bin/roary
@@ -0,0 +1,19 @@
+#!/usr/bin/env perl
+
+package Bio::Roary::Main::Roary;
+
+# ABSTRACT: Create a pan genome from a set of GFF files
+# PODNAME: roary
+
+=head1 SYNOPSIS
+
+Create a pan genome from a set of GFF files
+
+=cut
+
+use Cwd qw(abs_path);
+BEGIN { unshift( @INC, abs_path('./lib') ) }
+BEGIN { unshift( @INC, abs_path('./t/lib') ) }
+use Bio::Roary::CommandLine::Roary;
+
+Bio::Roary::CommandLine::Roary->new(args => \@ARGV, script_name => $0)->run;
diff --git a/bin/transfer_annotation_to_groups b/bin/transfer_annotation_to_groups
new file mode 100755
index 0000000..06a485e
--- /dev/null
+++ b/bin/transfer_annotation_to_groups
@@ -0,0 +1,19 @@
+#!/usr/bin/env perl
+
+package Bio::Roary::Main::TransferAnnotationToGroups;
+
+# ABSTRACT: Take in a groups file and a set of GFF files and transfer the consensus annotation
+# PODNAME: transfer_annotation_to_groups
+
+=head1 SYNOPSIS
+
+Take in a groups file and a set of GFF files and transfer the consensus annotation
+
+=cut
+
+use Cwd qw(abs_path);
+BEGIN { unshift( @INC, abs_path('./lib') ) }
+BEGIN { unshift( @INC, abs_path('./t/lib') ) }
+use Bio::Roary::CommandLine::TransferAnnotationToGroups;
+
+Bio::Roary::CommandLine::TransferAnnotationToGroups->new(args => \@ARGV, script_name => $0)->run;
diff --git a/deployment_process b/deployment_process
new file mode 100644
index 0000000..3eccc71
--- /dev/null
+++ b/deployment_process
@@ -0,0 +1,7 @@
+# Releasing a new version
+
+Update the version number in dist.ini
+Commit all changes.
+Tag with the current version.
+Push all changes, and on github.com submit,accepted pull request
+dzil release
diff --git a/dist.ini b/dist.ini
new file mode 100644
index 0000000..e1942c2
--- /dev/null
+++ b/dist.ini
@@ -0,0 +1,32 @@
+name = Bio-Roary
+version = 3.5.7
+author = Andrew J. Page <ap13 at sanger.ac.uk>
+license = GPL_3
+copyright_holder = Wellcome Trust Sanger Institute
+copyright_year = 2013
+main_module = lib/Bio/Roary.pm
+
+[MetaResources]
+homepage = http://www.sanger.ac.uk/
+repository.web = http://sanger-pathogens.github.io/Roary/
+repository.url = https://github.com/sanger-pathogens/Roary.git
+repository.type = git
+
+[@Basic]
+[PruneCruft]
+[ExtraTests]
+[AutoPrereqs]
+[PodWeaver]
+[PkgVersion]
+
+[Prereqs]
+PerlIO::utf8_strict = 0
+
+[Encoding]
+filename = t/data/kraken_test/database.idx
+filename = t/data/kraken_test/database.jdb
+filename = t/data/kraken_test/database.kdb
+filename = t/data/kraken_test/taxonomy/names.dmp
+filename = t/data/kraken_test/taxonomy/nodes.dmp
+
+encoding = bytes
diff --git a/install_dependencies.sh b/install_dependencies.sh
new file mode 100755
index 0000000..1dc2914
--- /dev/null
+++ b/install_dependencies.sh
@@ -0,0 +1,248 @@
+#!/bin/bash
+
+set -x
+set -eu
+
+start_dir=$(pwd)
+ROARY_LIB_DIR="${start_dir}/lib"
+ROARY_BIN_DIR="${start_dir}/bin"
+
+PARALLEL_VERSION=${PARALLEL_VERSION:-"20150522"}
+PARALLEL_DOWNLOAD_FILENAME="parallel-${PARALLEL_VERSION}.tar.bz2"
+PARALLEL_URL="http://ftp.gnu.org/gnu/parallel/${PARALLEL_DOWNLOAD_FILENAME}"
+
+BEDTOOLS_VERSION="2.24.0"
+BEDTOOLS_DOWNLOAD_FILENAME="bedtools-${BEDTOOLS_VERSION}.tar.gz"
+BEDTOOLS_URL="https://github.com/arq5x/bedtools2/releases/download/v${BEDTOOLS_VERSION}/${BEDTOOLS_DOWNLOAD_FILENAME}"
+
+CDHIT_SHORT_VERSION="4.6.3"
+CDHIT_LONG_VERSION="4.6.3-2015-0515"
+CDHIT_DOWNLOAD_FILENAME="cd-hit-${CDHIT_SHORT_VERSION}.tar.gz"
+CDHIT_URL="https://github.com/weizhongli/cdhit/releases/download/V${CDHIT_SHORT_VERSION}/cd-hit-v${CDHIT_LONG_VERSION}.tar.gz"
+
+PRANK_VERSION="0.140603"
+PRANK_DOWNLOAD_FILENAME="prank-msa-master.tar.gz"
+PRANK_URL="https://github.com/ariloytynoja/prank-msa/archive/master.tar.gz"
+
+BLAST_VERSION="2.2.30"
+BLAST_DOWNLOAD_FILENAME="ncbi-blast-${BLAST_VERSION}+-x64-linux.tar.gz"
+BLAST_URL="ftp://ftp.ncbi.nlm.nih.gov/blast/executables/blast+/${BLAST_VERSION}/${BLAST_DOWNLOAD_FILENAME}"
+
+MCL_VERSION="14-137"
+MCL_DOWNLOAD_FILENAME="mcl-${MCL_VERSION}.tar.gz"
+MCL_URL="http://micans.org/mcl/src/mcl-${MCL_VERSION}.tar.gz"
+
+FASTTREE_VERSION="2.1.8"
+FASTTREE_DOWNLOAD_FILENAME="FastTree-${FASTTREE_VERSION}.c"
+FASTTREE_URL="http://microbesonline.org/fasttree/FastTree-${FASTTREE_VERSION}.c"
+
+MAFFT_VERSION="7.221"
+MAFFT_DOWNLOAD_FILENAME="mafft-${MAFFT_VERSION}-without-extensions-src.tgz"
+MAFFT_URL="http://mafft.cbrc.jp/alignment/software/${MAFFT_DOWNLOAD_FILENAME}"
+
+# Make an install location
+if [ ! -d 'build' ]; then
+ mkdir build
+fi
+cd build
+build_dir=$(pwd)
+
+PARALLEL_DOWNLOAD_PATH="$(pwd)/${PARALLEL_DOWNLOAD_FILENAME}"
+BEDTOOLS_DOWNLOAD_PATH="$(pwd)/${BEDTOOLS_DOWNLOAD_FILENAME}"
+CDHIT_DOWNLOAD_PATH="$(pwd)/${CDHIT_DOWNLOAD_FILENAME}"
+PRANK_DOWNLOAD_PATH="$(pwd)/${PRANK_DOWNLOAD_FILENAME}"
+BLAST_DOWNLOAD_PATH="$(pwd)/${BLAST_DOWNLOAD_FILENAME}"
+MCL_DOWNLOAD_PATH="$(pwd)/${MCL_DOWNLOAD_FILENAME}"
+FASTTREE_DOWNLOAD_PATH="$(pwd)/${FASTTREE_DOWNLOAD_FILENAME}"
+MAFFT_DOWNLOAD_PATH="$(pwd)/${MAFFT_DOWNLOAD_FILENAME}"
+
+PARALLEL_BUILD_DIR="$(pwd)/parallel-${PARALLEL_VERSION}"
+BEDTOOLS_BUILD_DIR="$(pwd)/bedtools2"
+CDHIT_BUILD_DIR="$(pwd)/cd-hit-v${CDHIT_LONG_VERSION}"
+PRANK_BUILD_DIR="$(pwd)/prank-msa-master"
+BLAST_BUILD_DIR="$(pwd)/ncbi-blast-${BLAST_VERSION}+"
+MCL_BUILD_DIR="$(pwd)/mcl-${MCL_VERSION}"
+FASTTREE_BUILD_DIR="$(pwd)/fasttree"
+MAFFT_BUILD_DIR="$(pwd)/mafft-${MAFFT_VERSION}-without-extensions"
+
+
+download () {
+ download_url=$1
+ download_path=$2
+ cd $build_dir
+ if [ -e "$download_path" ]; then
+ echo "Skipping download of $download_url, $download_path already exists"
+ else
+ echo "Downloading $download_url to $download_path"
+ wget $download_url -O $download_path
+ pwd
+ fi
+}
+
+untar () {
+ to_untar=$1
+ expected_directory=$2
+ if [ -d "$expected_directory" ]; then
+ rm -rf $expected_directory
+ fi
+ echo "Untarring $to_untar to $expected_directory"
+ cd $build_dir
+ tar xzvf $to_untar
+ rm $to_untar
+ pwd
+}
+
+if [ -e "$BLAST_BUILD_DIR/bin/blastp" ]; then
+ echo "blast already untarred to $BLAST_BUILD_DIR, skipping"
+else
+ download $BLAST_URL $BLAST_DOWNLOAD_PATH
+ untar $BLAST_DOWNLOAD_PATH $BLAST_BUILD_DIR
+fi
+
+# Build parallel
+if [ -e "$PARALLEL_BUILD_DIR/src/parallel" ]; then
+ echo "Parallel already built, skipping"
+else
+ download $PARALLEL_URL $PARALLEL_DOWNLOAD_PATH
+ echo "Untarring parallel to $PARALLEL_BUILD_DIR"
+ tar xjvf $PARALLEL_DOWNLOAD_PATH
+ echo "Building parallel"
+ cd $PARALLEL_BUILD_DIR
+ ./configure
+ make
+fi
+
+# Build bedtools
+if [ -e "$BEDTOOLS_BUILD_DIR/bin/bedtools" ]; then
+ echo "Bedtools already built, skipping"
+else
+
+ download $BEDTOOLS_URL $BEDTOOLS_DOWNLOAD_PATH
+ untar $BEDTOOLS_DOWNLOAD_PATH $BEDTOOLS_BUILD_DIR
+ cd $BEDTOOLS_BUILD_DIR
+ echo "Building bedtools"
+ ls -alrt
+ make
+fi
+
+# Build cd-hit
+if [ -e "$CDHIT_BUILD_DIR/cd-hit" ]; then
+ echo "cd-hit already built, skipping"
+else
+ download $CDHIT_URL $CDHIT_DOWNLOAD_PATH
+ untar $CDHIT_DOWNLOAD_PATH $CDHIT_BUILD_DIR
+ echo "Building cd-hit"
+ cd $CDHIT_BUILD_DIR
+ make
+fi
+
+# Build prank
+if [ -e "$PRANK_BUILD_DIR/src/prank" ]; then
+ echo "prank already built, skipping"
+else
+ download $PRANK_URL $PRANK_DOWNLOAD_PATH
+ untar $PRANK_DOWNLOAD_PATH $PRANK_BUILD_DIR
+ echo "Building prank"
+ cd $PRANK_BUILD_DIR
+ cd src
+ make
+fi
+
+# Build MCL
+if [ -e "$MCL_BUILD_DIR/src/shmcl/mcl" ]; then
+ echo "MCL already built, skipping"
+else
+ download $MCL_URL $MCL_DOWNLOAD_PATH
+ untar $MCL_DOWNLOAD_PATH $MCL_BUILD_DIR
+ echo "Building MCL"
+ cd $MCL_BUILD_DIR
+ ./configure
+ make
+fi
+
+# Build FastTree
+if [ -e "$FASTTREE_BUILD_DIR/FastTree" ]; then
+ echo "FastTree already built, skipping"
+else
+ download $FASTTREE_URL $FASTTREE_DOWNLOAD_PATH
+ mkdir -p $FASTTREE_BUILD_DIR
+ mv $FASTTREE_DOWNLOAD_FILENAME $FASTTREE_BUILD_DIR
+ cd $FASTTREE_BUILD_DIR
+ echo "Building FastTree"
+ gcc -o FastTree FastTree-${FASTTREE_VERSION}.c -lm
+fi
+
+export MAFFT_INSTALL_DIR="${MAFFT_BUILD_DIR}/build"
+# Build MAFFT
+if [ -e "$MAFFT_BUILD_DIR/build/mafft" ]; then
+ echo "MAFFT already built, skipping"
+else
+ download $MAFFT_URL $MAFFT_DOWNLOAD_PATH
+ untar $MAFFT_DOWNLOAD_PATH $MAFFT_BUILD_DIR
+ echo "Building MAFFT"
+ cd $MAFFT_BUILD_DIR
+ mkdir -p $MAFFT_INSTALL_DIR
+ cd core
+ sed -i '1s!.*!PREFIX = $(MAFFT_INSTALL_DIR)!' Makefile
+ make
+ make install
+fi
+
+
+# Add things to PATH
+update_path () {
+ new_dir=$1
+ if [[ ! "$PATH" =~ (^|:)"${new_dir}"(:|$) ]]; then
+ echo "export PATH=${new_dir}:${PATH}"
+ export PATH=${new_dir}:${PATH}
+ fi
+}
+
+export PATH
+PARALLEL_BIN_DIR="$PARALLEL_BUILD_DIR/src"
+update_path $PARALLEL_BIN_DIR
+BEDTOOLS_BIN_DIR="$BEDTOOLS_BUILD_DIR/bin"
+update_path $BEDTOOLS_BIN_DIR
+CDHIT_BIN_DIR="$CDHIT_BUILD_DIR"
+update_path $CDHIT_BIN_DIR
+PRANK_BIN_DIR="$PRANK_BUILD_DIR/src"
+update_path $PRANK_BIN_DIR
+
+BLAST_BIN_DIR="$BLAST_BUILD_DIR/bin"
+update_path $BLAST_BIN_DIR
+
+MCL_BIN_DIR="$MCL_BUILD_DIR/src/shmcl"
+update_path $MCL_BIN_DIR
+MCL_BIN_DIR_2="$MCL_BUILD_DIR/src/alien/oxygen/src"
+update_path $MCL_BIN_DIR_2
+
+FASTTREE_BIN_DIR=$FASTTREE_BUILD_DIR
+update_path $FASTTREE_BIN_DIR
+MAFFT_BIN_DIR="$MAFFT_INSTALL_DIR/bin"
+update_path $MAFFT_BIN_DIR
+
+update_perl_path () {
+ new_dir=$1
+ PERL5LIB=${PERL5LIB-$new_dir}
+ if [[ ! "$PERL5LIB" =~ (^|:)"${new_dir}"(:|$) ]]; then
+ echo "export PERL5LIB=${new_dir}:${PERL5LIB}"
+ export PERL5LIB=${new_dir}:${PERL5LIB}
+ fi
+}
+
+BEDTOOLS_LIB_DIR="$BEDTOOLS_BUILD_DIR/lib"
+update_perl_path $BEDTOOLS_LIB_DIR
+
+cd $start_dir
+cpanm --notest Dist::Zilla
+dzil authordeps --missing | cpanm --notest
+dzil listdeps --missing | cpanm --notest
+
+cd $start_dir
+
+echo "Add the following lines to one of these files ~/.bashrc or ~/.bash_profile or ~/.profile"
+echo "export PATH=${ROARY_BIN_DIR}:${PARALLEL_BIN_DIR}:${BEDTOOLS_BIN_DIR}:${CDHIT_BIN_DIR}:${PRANK_BIN_DIR}:${BLAST_BIN_DIR}:${MCL_BIN_DIR}:${MCL_BIN_DIR_2}:${FASTTREE_BIN_DIR}:${MAFFT_BIN_DIR}:${PATH}"
+echo "export PERL5LIB=${ROARY_LIB_DIR}:${BEDTOOLS_LIB_DIR}:${PERL5LIB}"
+
+set +eu
+set +x
diff --git a/lib/Bio/Roary.pm b/lib/Bio/Roary.pm
new file mode 100644
index 0000000..d8b5fa3
--- /dev/null
+++ b/lib/Bio/Roary.pm
@@ -0,0 +1,146 @@
+package Bio::Roary;
+
+# ABSTRACT: Create a pan genome
+
+=head1 SYNOPSIS
+
+Create a pan genome
+
+=cut
+
+use Moose;
+use File::Copy;
+use Bio::Perl;
+use Bio::Roary::ParallelAllAgainstAllBlast;
+use Bio::Roary::CombinedProteome;
+use Bio::Roary::External::Cdhit;
+use Bio::Roary::External::Mcl;
+use Bio::Roary::InflateClusters;
+use Bio::Roary::AnalyseGroups;
+use Bio::Roary::GroupLabels;
+use Bio::Roary::AnnotateGroups;
+use Bio::Roary::GroupStatistics;
+use Bio::Roary::Output::GroupsMultifastasNucleotide;
+use Bio::Roary::External::PostAnalysis;
+use Bio::Roary::FilterFullClusters;
+use Bio::Roary::External::IterativeCdhit;
+use Bio::Roary::Output::BlastIdentityFrequency;
+
+has 'fasta_files' => ( is => 'rw', isa => 'ArrayRef', required => 1 );
+has 'input_files' => ( is => 'rw', isa => 'ArrayRef', required => 1 );
+has 'output_filename' => ( is => 'rw', isa => 'Str', default => 'clustered_proteins' );
+has 'output_pan_geneome_filename' => ( is => 'rw', isa => 'Str', default => 'pan_genome.fa' );
+has 'output_statistics_filename' => ( is => 'rw', isa => 'Str', default => 'gene_presence_absence.csv' );
+has 'job_runner' => ( is => 'rw', isa => 'Str', default => 'Local' );
+has 'cpus' => ( is => 'ro', isa => 'Int', default => 1 );
+has 'makeblastdb_exec' => ( is => 'rw', isa => 'Str', default => 'makeblastdb' );
+has 'blastp_exec' => ( is => 'rw', isa => 'Str', default => 'blastp' );
+has 'mcxdeblast_exec' => ( is => 'ro', isa => 'Str', default => 'mcxdeblast' );
+has 'mcl_exec' => ( is => 'ro', isa => 'Str', default => 'mcl' );
+has 'perc_identity' => ( is => 'ro', isa => 'Num', default => 98 );
+has 'dont_delete_files' => ( is => 'ro', isa => 'Bool', default => 0 );
+has 'dont_create_rplots' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'dont_split_groups' => ( is => 'ro', isa => 'Bool', default => 0 );
+has 'verbose_stats' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'translation_table' => ( is => 'rw', isa => 'Int', default => 11 );
+has 'group_limit' => ( is => 'rw', isa => 'Num', default => 50000 );
+has 'core_definition' => ( is => 'rw', isa => 'Num', default => 1.0 );
+has 'verbose' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'mafft' => ( is => 'ro', isa => 'Bool', default => 0 );
+
+has 'output_multifasta_files' => ( is => 'ro', isa => 'Bool', default => 0 );
+
+sub run {
+ my ($self) = @_;
+
+ my $output_combined_filename = '_combined_files';
+ my $output_cd_hit_filename = '_clustered';
+ my $output_blast_results_filename = '_blast_results';
+ my $output_mcl_filename = '_uninflated_mcl_groups';
+ my $output_filtered_clustered_fasta = '_clustered_filtered.fa';
+ my $cdhit_groups = $output_combined_filename.'.groups';
+
+
+ unlink($cdhit_groups) unless($self->dont_delete_files == 1);
+
+ print "Combine proteins into a single file\n" if($self->verbose);
+ my $combine_fasta_files = Bio::Roary::CombinedProteome->new(
+ proteome_files => $self->fasta_files,
+ output_filename => $output_combined_filename,
+ );
+ $combine_fasta_files->create_combined_proteome_file;
+
+ my $number_of_input_files = @{$self->input_files};
+
+ print "Iteratively run cd-hit\n" if($self->verbose);
+ my $iterative_cdhit= Bio::Roary::External::IterativeCdhit->new(
+ output_cd_hit_filename => $output_cd_hit_filename,
+ output_combined_filename => $output_combined_filename,
+ number_of_input_files => $number_of_input_files,
+ output_filtered_clustered_fasta => $output_filtered_clustered_fasta,
+ job_runner => $self->job_runner,
+ cpus => $self->cpus
+ );
+
+ $iterative_cdhit->run();
+
+ print "Parallel all against all blast\n" if($self->verbose);
+ my $blast_obj = Bio::Roary::ParallelAllAgainstAllBlast->new(
+ fasta_file => $output_cd_hit_filename,
+ blast_results_file_name => $output_blast_results_filename,
+ job_runner => $self->job_runner,
+ cpus => $self->cpus,
+ makeblastdb_exec => $self->makeblastdb_exec,
+ blastp_exec => $self->blastp_exec,
+ perc_identity => $self->perc_identity
+ );
+ $blast_obj->run();
+
+ my $blast_identity_frequency_obj = Bio::Roary::Output::BlastIdentityFrequency->new(
+ input_filename => $output_blast_results_filename,
+ );
+ $blast_identity_frequency_obj->create_file();
+
+ print "Cluster with MCL\n" if($self->verbose);
+ my $mcl = Bio::Roary::External::Mcl->new(
+ blast_results => $output_blast_results_filename,
+ mcxdeblast_exec => $self->mcxdeblast_exec,
+ mcl_exec => $self->mcl_exec,
+ job_runner => $self->job_runner,
+ cpus => $self->cpus,
+ output_file => $output_mcl_filename
+ );
+ $mcl->run();
+
+ unlink($output_blast_results_filename) unless($self->dont_delete_files == 1);
+
+ my $post_analysis = Bio::Roary::External::PostAnalysis->new(
+ job_runner => $self->job_runner,
+ cpus => $self->cpus,
+ fasta_files => $self->fasta_files,
+ input_files => $self->input_files,
+ output_filename => $self->output_filename,
+ output_pan_geneome_filename => $self->output_pan_geneome_filename,
+ output_statistics_filename => $self->output_statistics_filename,
+ clusters_filename => $output_cd_hit_filename.'.clstr',
+ dont_wait => 1,
+ output_multifasta_files => $self->output_multifasta_files,
+ dont_delete_files => $self->dont_delete_files,
+ dont_create_rplots => $self->dont_create_rplots,
+ dont_split_groups => $self->dont_split_groups,
+ verbose_stats => $self->verbose_stats,
+ translation_table => $self->translation_table,
+ group_limit => $self->group_limit,
+ core_definition => $self->core_definition,
+ verbose => $self->verbose,
+ mafft => $self->mafft,
+ );
+ $post_analysis->run();
+
+}
+
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/AccessoryBinaryFasta.pm b/lib/Bio/Roary/AccessoryBinaryFasta.pm
new file mode 100644
index 0000000..b398878
--- /dev/null
+++ b/lib/Bio/Roary/AccessoryBinaryFasta.pm
@@ -0,0 +1,100 @@
+package Bio::Roary::AccessoryBinaryFasta;
+
+# ABSTRACT: Output a FASTA file which represents the binary presence and absence of genes in the accessory genome
+
+=head1 SYNOPSIS
+
+Output a FASTA file which represents the binary presence and absence of genes in the accessory genome
+ use Bio::Roary::AccessoryBinaryFasta;
+ my $obj = Bio::Roary::AccessoryBinaryFasta->new(input_files => ['abc','efg'],
+ groups_to_files => {'group_1' => ['abc'], group_2 => ['abc', 'efg']}
+ );
+ $obj->create_accessory_binary_fasta();
+=cut
+
+use Moose;
+use POSIX;
+use Bio::Roary::AnnotateGroups;
+use Bio::Roary::AnalyseGroups;
+use Bio::Roary::Exceptions;
+use Bio::SeqIO;
+use File::Basename;
+
+has 'input_files' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'annotate_groups_obj' => ( is => 'ro', isa => 'Bio::Roary::AnnotateGroups', required => 1 );
+has 'analyse_groups_obj' => ( is => 'ro', isa => 'Bio::Roary::AnalyseGroups', required => 1 );
+has 'output_filename' => ( is => 'ro', isa => 'Str', default => 'accessory_binary_genes.fa' );
+has 'lower_bound_percentage' => ( is => 'ro', isa => 'Int', default => 5 );
+has 'upper_bound_percentage' => ( is => 'ro', isa => 'Int', default => 5 );
+has 'max_accessory_to_include' => ( is => 'ro', isa => 'Int', default => 4000 );
+has 'groups_to_files' => ( is => 'ro', isa => 'HashRef', lazy => 1, builder => '_build__groups_to_files' );
+has '_lower_bound_value' => ( is => 'ro', isa => 'Int', lazy => 1, builder => '_build__lower_bound_value' );
+has '_upper_bound_value' => ( is => 'ro', isa => 'Int', lazy => 1, builder => '_build__upper_bound_value' );
+
+sub _build__groups_to_files {
+ my ($self) = @_;
+ my %groups_to_files;
+ for my $group ( @{ $self->annotate_groups_obj->_groups } ) {
+ my $genes = $self->annotate_groups_obj->_groups_to_id_names->{$group};
+ my %filenames;
+ for my $gene_name ( @{$genes} ) {
+ my $filename = $self->analyse_groups_obj->_genes_to_file->{$gene_name};
+ push( @{ $filenames{$filename} }, $gene_name );
+ }
+ $groups_to_files{$group} = \%filenames;
+ }
+
+ return \%groups_to_files;
+}
+
+sub _build__lower_bound_value {
+ my ($self) = @_;
+ my $num_files = @{ $self->input_files };
+ return ceil( $num_files * ( $self->lower_bound_percentage / 100 ) );
+}
+
+sub _build__upper_bound_value {
+ my ($self) = @_;
+ my $num_files = @{ $self->input_files };
+ return $num_files - ceil( $num_files * ( $self->upper_bound_percentage / 100 ) );
+}
+
+sub create_accessory_binary_fasta {
+ my ($self) = @_;
+ my $out_seq_io = Bio::SeqIO->new( -file => ">" . $self->output_filename, -format => 'Fasta' );
+
+ for my $full_filename ( @{ $self->input_files } ) {
+ my($filename, $dirs, $suffix) = fileparse($full_filename);
+
+ my $output_sequence = '';
+ my $sample_name = $filename;
+ $sample_name =~ s!\.gff\.proteome\.faa!!;
+
+ my $gene_count = 0;
+ for my $group ( sort keys %{ $self->groups_to_files } ) {
+ last if($gene_count > $self->max_accessory_to_include);
+
+ my @files = keys %{ $self->groups_to_files->{$group} };
+
+ next if ( @files <= $self->_lower_bound_value || @files > $self->_upper_bound_value );
+
+ my $group_to_file_genes = $self->groups_to_files->{$group}->{$full_filename};
+ if ( defined($group_to_file_genes) && @{$group_to_file_genes} > 0 ) {
+ $output_sequence .= 'A';
+ }
+ else {
+ $output_sequence .= 'C';
+ }
+ $gene_count++;
+
+ }
+ next if($output_sequence eq '');
+ $out_seq_io->write_seq( Bio::Seq->new( -display_id => $sample_name, -seq => $output_sequence ) );
+ }
+ return 1;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/AccessoryClustering.pm b/lib/Bio/Roary/AccessoryClustering.pm
new file mode 100644
index 0000000..95110e2
--- /dev/null
+++ b/lib/Bio/Roary/AccessoryClustering.pm
@@ -0,0 +1,95 @@
+package Bio::Roary::AccessoryClustering;
+
+# ABSTRACT: Take an a clusters file from CD-hit and the fasta file and output a fasta file without full clusters
+
+=head1 SYNOPSIS
+
+Take an a clusters file from CD-hit and the fasta file and output a fasta file without full clusters
+ use Bio::Roary::AccessoryClustering;
+
+ my $obj = Bio::Roary::AccessoryClustering->new(
+ input_file => 'accessory_binary_genes.fa',
+ identity => 0.96,
+ cpus => 10,
+ );
+ $obj->sample_weights();
+
+=cut
+
+use Moose;
+use Bio::Roary::External::Cdhit;
+with 'Bio::Roary::ClustersRole';
+
+has 'input_file' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'identity' => ( is => 'ro', isa => 'Num', default => 0.9 );
+has 'cpus' => ( is => 'ro', isa => 'Int', default => 1 );
+has '_output_cd_hit_filename' => ( is => 'ro', isa => 'Str', default => '_accessory_clusters' );
+has 'clusters_to_samples' => ( is => 'ro', isa => 'HashRef', lazy => 1, builder => '_build_clusters_to_samples' );
+has 'samples_to_clusters' => ( is => 'ro', isa => 'HashRef', lazy => 1, builder => '_build_samples_to_clusters' );
+has 'sample_weights' => ( is => 'ro', isa => 'HashRef', lazy => 1, builder => '_build_sample_weights' );
+has 'clusters_filename' => ( is => 'ro', isa => 'Str', lazy => 1, builder => '_build_clusters_filename' );
+has 'clusters' => ( is => 'ro', isa => 'HashRef', lazy => 1, builder => '_build__clusters' );
+
+sub _build_sample_weights {
+ my ($self) = @_;
+ my %sample_weights;
+ for my $cluster_name ( keys %{ $self->clusters_to_samples } ) {
+ my $cluster_size = @{ $self->clusters_to_samples->{$cluster_name} };
+ for my $sample_name ( @{ $self->clusters_to_samples->{$cluster_name} } ) {
+ $sample_weights{$sample_name} = 1 / $cluster_size;
+ }
+ }
+ return \%sample_weights;
+}
+
+sub _build_samples_to_clusters {
+ my ($self) = @_;
+ my %samples_to_clusters;
+ for my $cluster_name ( keys %{ $self->clusters_to_samples } ) {
+ for my $sample_name ( @{ $self->clusters_to_samples->{$cluster_name} } ) {
+ $samples_to_clusters{$sample_name} = $cluster_name;
+ }
+ }
+ return \%samples_to_clusters;
+}
+
+sub _build_clusters_filename {
+ my ($self) = @_;
+ return $self->_output_cd_hit_filename . '.clstr';
+}
+
+sub _build_clusters_to_samples {
+ my ($self) = @_;
+
+ my $cdhit_obj = Bio::Roary::External::Cdhit->new(
+ input_file => $self->input_file,
+ output_base => $self->_output_cd_hit_filename,
+ _length_difference_cutoff => 1,
+ _sequence_identity_threshold => $self->identity,
+ cpus => $self->cpus
+ );
+ $cdhit_obj->run();
+ my $clusterd_genes = $self->_clustered_genes;
+
+ for my $cluster_name ( keys %{$clusterd_genes} ) {
+ my $found = 0;
+ for my $gene_name ( @{ $clusterd_genes->{$cluster_name} } ) {
+ if ( $gene_name eq $cluster_name ) {
+ $found = 1;
+ last;
+ }
+ }
+
+ if ( $found == 0 ) {
+ push( @{ $clusterd_genes->{$cluster_name} }, $cluster_name );
+ }
+ }
+
+ return $clusterd_genes;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
+
diff --git a/lib/Bio/Roary/AnalyseGroups.pm b/lib/Bio/Roary/AnalyseGroups.pm
new file mode 100644
index 0000000..2e72536
--- /dev/null
+++ b/lib/Bio/Roary/AnalyseGroups.pm
@@ -0,0 +1,119 @@
+package Bio::Roary::AnalyseGroups;
+
+# ABSTRACT: Take in a groups file and the original FASTA files and create plots and stats
+
+=head1 SYNOPSIS
+
+Take in a groups file and the original FASTA files and create plots and stats
+ use Bio::Roary::AnalyseGroups;
+
+ my $plot_groups_obj = Bio::Roary::AnalyseGroups->new(
+ fasta_files => $fasta_files,
+ groups_filename => $groups_filename,
+ output_filename => $output_filename
+ );
+ $plot_groups_obj->create_plots();
+
+=cut
+
+use Moose;
+use Bio::Roary::Exceptions;
+
+has 'fasta_files' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'groups_filename' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'output_filename' => ( is => 'ro', isa => 'Str', default => 'summary_of_groups' );
+
+has '_number_of_isolates' => ( is => 'ro', isa => 'Int', lazy => 1, builder => '_builder__number_of_isolates' );
+has '_genes_to_file' => ( is => 'rw', isa => 'HashRef' );
+has '_files_to_genes' => ( is => 'ro', isa => 'HashRef', lazy => 1, builder => '_builder__files_to_genes' );
+has '_groups_to_genes' => ( is => 'ro', isa => 'HashRef', lazy => 1, builder => '_builder__groups_to_genes' );
+has '_genes_to_groups' => ( is => 'rw', isa => 'HashRef' );
+
+has '_groups' => ( is => 'ro', isa => 'ArrayRef', lazy => 1, builder => '_builder__groups' );
+
+
+sub BUILD {
+ my ($self) = @_;
+ # This triggers _genes_to_groups to be built
+ $self->_groups_to_genes;
+ # This triggers _genes_to_file to be built
+ $self->_files_to_genes;
+}
+
+sub _builder__groups
+{
+ my ($self) = @_;
+ my @groups = sort keys %{$self->_groups_to_genes};
+ return \@groups;
+}
+
+sub _builder__number_of_isolates {
+ my ($self) = @_;
+ return @{ $self->fasta_files };
+}
+
+sub _builder__files_to_genes {
+ my ($self) = @_;
+ my %files_to_genes;
+ my %genes_to_file;
+ for my $filename ( @{ $self->fasta_files } ) {
+ open( my $fh, '-|', 'grep \> ' . $filename . ' | awk \'{print $1}\' | sed \'s/>//\' ' );
+ while (<$fh>) {
+ chomp;
+ my $gene_name = $_;
+ next if($gene_name eq "");
+ push( @{ $files_to_genes{$filename} }, $gene_name );
+ $genes_to_file{$gene_name} = $filename;
+ }
+ close($fh);
+ }
+ $self->_genes_to_file(\%genes_to_file);
+
+ return \%files_to_genes;
+}
+
+sub _count_num_files_in_group {
+ my ( $self, $genes ) = @_;
+ my $count = 0;
+ my %filename_freq;
+ for my $gene ( @{$genes} ) {
+ next if ( $gene eq "" );
+ if ( defined( $self->_genes_to_file->{$gene} ) ) {
+ $filename_freq{ $self->_genes_to_file->{$gene} }++;
+ }
+ }
+ my @uniq_filenames = keys %filename_freq;
+ return @uniq_filenames;
+}
+
+sub _builder__groups_to_genes {
+ my ($self) = @_;
+ my %groups_to_genes;
+ my %genes_to_groups;
+
+ open( my $fh, $self->groups_filename )
+ or Bio::Roary::Exceptions::FileNotFound->throw( error => "Group file not found:" . $self->groups_filename );
+ while (<$fh>) {
+ chomp;
+ my $line = $_;
+ if ( $line =~ /^(.+): (.+)$/ ) {
+ my $group_name = $1;
+ my $genes = $2;
+ my @elements = split( /[\s\t]+/, $genes );
+ $groups_to_genes{$group_name} = \@elements;
+
+ for my $gene (@elements) {
+ $genes_to_groups{$gene} = $group_name;
+ }
+ }
+ }
+ $self->_genes_to_groups(\%genes_to_groups);
+
+ return \%groups_to_genes;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
+
diff --git a/lib/Bio/Roary/AnnotateGroups.pm b/lib/Bio/Roary/AnnotateGroups.pm
new file mode 100644
index 0000000..2c02b1a
--- /dev/null
+++ b/lib/Bio/Roary/AnnotateGroups.pm
@@ -0,0 +1,356 @@
+package Bio::Roary::AnnotateGroups;
+
+# ABSTRACT: Take in a group file and assosiated GFF files for the isolates and update the group name to the gene name
+
+=head1 SYNOPSIS
+
+Take in a group file and assosiated GFF files for the isolates and update the group name to the gene name
+ use Bio::Roary::AnnotateGroups;
+
+ my $obj = Bio::Roary::AnnotateGroups->new(
+ gff_files => ['abc.gff','efg.gff'],
+ output_filename => 'example_output.fa',
+ groups_filename => 'groupsfile',
+ );
+ $obj->reannotate;
+
+=cut
+
+use Moose;
+use Bio::Roary::Exceptions;
+use Bio::Roary::GeneNamesFromGFF;
+use Array::Utils qw(array_minus);
+use List::Util qw(max min sum);
+use File::Grep qw(fgrep);
+
+has 'gff_files' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'output_filename' => ( is => 'ro', isa => 'Str', default => 'reannotated_groups_file' );
+has 'groups_filename' => ( is => 'ro', isa => 'Str', required => 1 );
+has '_ids_to_gene_names' => ( is => 'ro', isa => 'HashRef', lazy => 1, builder => '_build__ids_to_gene_names' );
+has '_ids_to_product' => ( is => 'rw', isa => 'HashRef', default => sub { {} } );
+has '_ids_to_gene_size' => ( is => 'rw', isa => 'HashRef', default => sub { {} } );
+has 'group_nucleotide_lengths' => ( is => 'ro', isa => 'HashRef', lazy => 1, builder => '_build_group_nucleotide_lengths');
+
+has '_groups_to_id_names' => ( is => 'ro', isa => 'HashRef', lazy => 1, builder => '_builder__groups_to_id_names' );
+has '_output_fh' => ( is => 'ro', lazy => 1, builder => '_build__output_fh' );
+has '_groups_to_consensus_gene_names' =>
+ ( is => 'rw', isa => 'HashRef', lazy => 1, builder => '_build__groups_to_consensus_gene_names' );
+has '_filtered_gff_files' => ( is => 'ro', isa => 'ArrayRef', lazy => 1, builder => '_build__filtered_gff_files' );
+has '_number_of_files' => ( is => 'ro', isa => 'Int', lazy => 1, builder => '_build__number_of_files' );
+has '_ids_to_groups' => ( is => 'rw', isa => 'HashRef', lazy => 1, builder => '_builder__ids_to_groups' );
+has '_group_counter' => ( is => 'rw', isa => 'Int', lazy => 1, builder => '_builder__group_counter' );
+has '_group_default_prefix' => ( is => 'rw', isa => 'Str', default => 'group_' );
+has '_ids_to_verbose_stats' => ( is => 'rw', isa => 'HashRef', lazy_build => 1 );
+
+sub BUILD {
+ my ($self) = @_;
+ $self->_ids_to_gene_names;
+}
+
+sub _builder__group_counter {
+ my ($self) = @_;
+ my $prefix = $self->_group_default_prefix;
+ my $highest_group = 0;
+ for my $group ( @{ $self->_groups } ) {
+ if ( $group =~ /$prefix([\d]+)$/ ) {
+ my $group_id = $1;
+ if ( $group_id > $highest_group ) {
+ $highest_group = $group_id;
+ }
+ }
+ }
+ return $highest_group + 1;
+}
+
+sub _generate__ids_to_groups {
+ my ($self) = @_;
+ my %ids_to_groups;
+
+ for my $group ( keys %{ $self->_groups_to_id_names } ) {
+ for my $id_name ( @{ $self->_groups_to_id_names->{$group} } ) {
+ $ids_to_groups{$id_name} = $group;
+ }
+ }
+ return \%ids_to_groups;
+}
+
+sub _builder__ids_to_groups {
+ my ($self) = @_;
+ return $self->_generate__ids_to_groups;
+}
+
+sub _build__output_fh {
+ my ($self) = @_;
+ open( my $fh, '>', $self->output_filename )
+ or Bio::Roary::Exceptions::CouldntWriteToFile->throw(
+ error => "Couldnt write output file:" . $self->output_filename );
+ return $fh;
+}
+
+sub _build__filtered_gff_files {
+ my ($self) = @_;
+ my @gff_files = grep( /\.gff$/, @{ $self->gff_files } );
+ return \@gff_files;
+}
+
+sub _build__ids_to_gene_names {
+ my ($self) = @_;
+ my %ids_to_gene_names;
+ my %ids_to_product;
+ my %ids_to_gene_size;
+ for my $filename ( @{ $self->_filtered_gff_files } ) {
+ my $gene_names_from_gff = Bio::Roary::GeneNamesFromGFF->new( gff_file => $filename );
+ my %id_to_gene_lookup = %{ $gene_names_from_gff->ids_to_gene_name };
+ @ids_to_gene_names{ keys %id_to_gene_lookup } = values %id_to_gene_lookup;
+
+ my %id_to_product_lookup = %{ $gene_names_from_gff->ids_to_product };
+ @ids_to_product{ keys %id_to_product_lookup } = values %id_to_product_lookup;
+
+ my %ids_to_gene_size_lookup = %{ $gene_names_from_gff->ids_to_gene_size };
+ @ids_to_gene_size{ keys %ids_to_gene_size_lookup } = values %ids_to_gene_size_lookup;
+ }
+ $self->_ids_to_product( \%ids_to_product );
+ $self->_ids_to_gene_size( \%ids_to_gene_size );
+
+ return \%ids_to_gene_names;
+}
+
+sub _build__ids_to_verbose_stats {
+ my $self = shift;
+
+ my @matches_hash = fgrep { /ID=/i } @{ $self->_filtered_gff_files };
+ my @matches;
+ foreach my $m ( @matches_hash ){
+ push( @matches, values %{$m->{matches}} );
+ }
+ # chomp @matches;
+
+ my %verbose;
+ foreach my $line ( @matches ){
+ my ( $id, $inf, $prod );
+ if( $line =~ m/ID=["']?([^;"']+)["']?;?/i ){
+ $id = $1;
+ }
+ else {
+ next;
+ }
+
+ $inf = $1 if ( $line =~ m/inference=([^;]+);/ );
+ $prod = $1 if ( $line =~ m/product=([^;]+)[;\n]/ );
+
+ my %info = ( 'inference' => $inf, 'product' => $prod );
+ $verbose{$id} = \%info;
+ }
+ return \%verbose;
+}
+
+
+sub consensus_product_for_id_names {
+ my ( $self, $id_names ) = @_;
+ my %product_freq;
+ for my $id_name ( @{$id_names} ) {
+ next unless ( defined( $self->_ids_to_product->{$id_name} ) );
+ $product_freq{ $self->_ids_to_product->{$id_name} }++;
+ }
+
+ my @sorted_product_keys = sort { $product_freq{$b} <=> $product_freq{$a} } keys(%product_freq);
+
+ if ( @sorted_product_keys > 0 ) {
+ return $sorted_product_keys[0];
+ }
+ else {
+ return '';
+ }
+}
+
+sub _builder__groups_to_id_names {
+ my ($self) = @_;
+ my %groups_to_id_names;
+
+ open( my $fh, $self->groups_filename )
+ or Bio::Roary::Exceptions::FileNotFound->throw( error => "Group file not found:" . $self->groups_filename );
+ while (<$fh>) {
+ chomp;
+ my $line = $_;
+ if ( $line =~ /^(.+): (.+)$/ ) {
+ my $group_name = $1;
+ my $genes = $2;
+ my @elements = split( /[\s\t]+/, $genes );
+ $groups_to_id_names{$group_name} = \@elements;
+ }
+ }
+
+ return \%groups_to_id_names;
+}
+
+sub _groups {
+ my ($self) = @_;
+ my @groups = keys %{ $self->_groups_to_id_names };
+ return \@groups;
+}
+
+sub _ids_grouped_by_gene_name_for_group {
+ my ( $self, $group_name ) = @_;
+ my %gene_name_freq;
+ for my $id_name ( @{ $self->_groups_to_id_names->{$group_name} } ) {
+ if ( defined( $self->_ids_to_gene_names->{$id_name} ) && $self->_ids_to_gene_names->{$id_name} ne "" ) {
+ push( @{ $gene_name_freq{ $self->_ids_to_gene_names->{$id_name} } }, $id_name );
+ }
+ }
+ return \%gene_name_freq;
+}
+
+sub _consensus_gene_name_for_group {
+ my ( $self, $group_name ) = @_;
+ my $gene_name_freq = $self->_ids_grouped_by_gene_name_for_group($group_name);
+
+ my @sorted_gene_names = sort { @{ $gene_name_freq->{$b} } <=> @{ $gene_name_freq->{$a} } } keys %{$gene_name_freq};
+ if ( @sorted_gene_names > 0 ) {
+ return shift(@sorted_gene_names);
+ }
+ else {
+ return $group_name;
+ }
+}
+
+sub _build_group_nucleotide_lengths
+{
+ my ($self) = @_;
+ my %group_nucleotide_lengths;
+ for my $group_name (keys %{ $self->_groups_to_id_names } )
+ {
+ my @gene_lengths;
+ for my $gene_id (@{$self->_groups_to_id_names->{$group_name}})
+ {
+ my $current_gene_size = $self->_ids_to_gene_size->{$gene_id};
+ next unless(defined($current_gene_size) );
+ next if($current_gene_size < 1);
+ push(@gene_lengths, $current_gene_size);
+ }
+
+ next if(@gene_lengths == 0);
+ my $average_gene_size = (int((sum @gene_lengths)/@gene_lengths)) || 0;
+ my $min_gene_size = (min @gene_lengths) || 0;
+ my $max_gene_size = (max @gene_lengths) || 0;
+ $group_nucleotide_lengths{$group_name} = {'min' => $min_gene_size, 'max' =>$max_gene_size , 'average' => $average_gene_size};
+ }
+ return \%group_nucleotide_lengths;
+}
+
+sub _generate_groups_to_consensus_gene_names {
+ my ($self) = @_;
+ my %groups_to_gene_names;
+ my %gene_name_freq;
+ my $group_prefix = $self->_group_default_prefix;
+
+ # These are already annotated
+ for my $group_name ( sort { @{ $self->_groups_to_id_names->{$b} } <=> @{ $self->_groups_to_id_names->{$a} } }
+ keys %{ $self->_groups_to_id_names } )
+ {
+ next if ( $group_name =~ /$group_prefix/ );
+ $groups_to_gene_names{$group_name} = $group_name;
+ }
+
+ for my $group_name ( sort { @{ $self->_groups_to_id_names->{$b} } <=> @{ $self->_groups_to_id_names->{$a} } }
+ keys %{ $self->_groups_to_id_names } )
+ {
+ next unless ( $group_name =~ /$group_prefix/ );
+ my $consensus_gene_name = $self->_consensus_gene_name_for_group($group_name);
+
+ if ( defined( $gene_name_freq{$consensus_gene_name} ) ) {
+ $groups_to_gene_names{$group_name} = $group_name;
+ }
+ else {
+ $groups_to_gene_names{$group_name} = $consensus_gene_name;
+ $gene_name_freq{$consensus_gene_name}++;
+ }
+ }
+ return \%groups_to_gene_names;
+}
+
+sub _build__groups_to_consensus_gene_names {
+ my ($self) = @_;
+ return $self->_generate_groups_to_consensus_gene_names;
+}
+
+sub _build__number_of_files {
+ my ($self) = @_;
+ return @{ $self->gff_files };
+}
+
+
+sub _split_groups {
+ my ($self) = @_;
+
+ $self->_groups_to_consensus_gene_names( $self->_generate_groups_to_consensus_gene_names );
+ $self->_ids_to_groups( $self->_generate__ids_to_groups );
+}
+
+sub _remove_ids_from_group {
+ my ( $self, $ids_to_remove, $group ) = @_;
+
+ my @remaining_ids = array_minus( @{ $self->_groups_to_id_names->{$group} }, @{ $ids_to_remove } );
+ $self->_groups_to_id_names->{$group} = \@remaining_ids;
+ if ( @{ $self->_groups_to_id_names->{$group} } == 0 ) {
+ delete( $self->_groups_to_id_names->{$group} );
+ }
+}
+
+sub reannotate {
+ my ($self) = @_;
+
+ $self->_split_groups;
+
+ my %groups_to_id_names = %{ $self->_groups_to_id_names };
+ for
+ my $group_name ( sort { @{ $groups_to_id_names{$b} } <=> @{ $groups_to_id_names{$a} } } keys %groups_to_id_names )
+ {
+ my $consensus_gene_name = $self->_groups_to_consensus_gene_names->{$group_name};
+ print { $self->_output_fh } $consensus_gene_name . ": "
+ . join( "\t", @{ $self->_groups_to_id_names->{$group_name} } ) . "\n";
+ }
+ close( $self->_output_fh );
+ return $self;
+}
+
+sub full_annotation {
+ my ( $self, $group ) = @_;
+
+ my @id_names = @{ $self->_groups_to_id_names->{$group} };
+
+ my %product_freq;
+ for my $id_name ( @id_names ) {
+ next unless ( defined( $self->_ids_to_verbose_stats->{$id_name}->{'product'} ) );
+ $product_freq{ $self->_ids_to_verbose_stats->{$id_name}->{'product'} }++;
+ }
+
+ my @sorted_product_keys = sort { $product_freq{$b} <=> $product_freq{$a} } keys(%product_freq);
+
+ if ( @sorted_product_keys > 0 ) {
+ return join('; ', @sorted_product_keys);
+ }
+ else {
+ return '';
+ }
+
+}
+
+sub inference {
+ my ( $self, $group ) = @_;
+
+ my @infs;
+ foreach my $g ( @{ $self->_groups_to_id_names->{$group} } ){
+ next unless ( defined $self->_ids_to_verbose_stats->{$g}->{'inference'} );
+ push( @infs, $self->_ids_to_verbose_stats->{$g}->{'inference'} );
+ }
+
+ # maybe make a consensus in the future?
+
+ return $infs[0];
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
+
\ No newline at end of file
diff --git a/lib/Bio/Roary/AssemblyStatistics.pm b/lib/Bio/Roary/AssemblyStatistics.pm
new file mode 100644
index 0000000..cc0b32a
--- /dev/null
+++ b/lib/Bio/Roary/AssemblyStatistics.pm
@@ -0,0 +1,207 @@
+package Bio::Roary::AssemblyStatistics;
+
+# ABSTRACT: Given a spreadsheet of gene presence and absense calculate some statistics
+
+=head1 SYNOPSIS
+
+Given a spreadsheet of gene presence and absense calculate some statistics
+
+=cut
+
+use Moose;
+use Bio::Roary::ExtractCoreGenesFromSpreadsheet;
+use Log::Log4perl qw(:easy);
+with 'Bio::Roary::SpreadsheetRole';
+
+has 'output_filename' => ( is => 'ro', isa => 'Str', default => 'assembly_statistics.csv' );
+has 'job_runner' => ( is => 'ro', isa => 'Str', default => 'Local' );
+has 'cpus' => ( is => 'ro', isa => 'Int', default => 1 );
+has 'core_definition' => ( is => 'rw', isa => 'Num', default => 0.99 );
+has '_cloud_percentage' => ( is => 'rw', isa => 'Num', default => 0.15 );
+has '_shell_percentage' => ( is => 'rw', isa => 'Num', default => 0.95 );
+has '_soft_core_percentage' => ( is => 'rw', isa => 'Num', default => 0.99 );
+has 'verbose' => ( is => 'ro', isa => 'Bool', default => 0 );
+has 'contiguous_window' => ( is => 'ro', isa => 'Int', default => 10 );
+has 'ordered_genes' => ( is => 'ro', isa => 'ArrayRef', lazy => 1, builder => '_build_ordered_genes' );
+has '_genes_to_rows' => ( is => 'ro', isa => 'HashRef', lazy => 1, builder => '_build__genes_to_rows' );
+has 'all_sample_statistics' => ( is => 'ro', isa => 'HashRef', lazy => 1, builder => '_build_all_sample_statistics' );
+has 'sample_names_to_column_index' => ( is => 'rw', isa => 'Maybe[HashRef]' );
+has 'summary_output_filename'=> ( is => 'ro', isa => 'Str', default => 'summary_statistics.txt' );
+has 'logger' => ( is => 'ro', lazy => 1, builder => '_build_logger');
+has 'gene_category_count' => ( is => 'ro', isa => 'HashRef', lazy => 1, builder => '_build_gene_category_count' );
+
+sub BUILD {
+ my ($self) = @_;
+ $self->_genes_to_rows;
+ $self->gene_category_count;
+}
+
+sub _build_logger
+{
+ my ($self) = @_;
+ Log::Log4perl->easy_init(level => $ERROR);
+ my $logger = get_logger();
+ return $logger;
+}
+
+sub create_summary_output
+{
+ my ($self) = @_;
+ open(my $fh, '>', $self->summary_output_filename) or Bio::Roary::Exceptions::CouldntWriteToFile->throw(error => "Couldnt write to ".$self->summary_output_filename);
+
+ my $core_percentage = $self->core_definition()*100;
+ my $soft_core_percentage = $self->_soft_core_percentage*100;
+ my $shell_percentage = $self->_shell_percentage()*100;
+ my $cloud_percentage = $self->_cloud_percentage()*100;
+
+ my $core_genes = ($self->gene_category_count->{core} ? $self->gene_category_count->{core} : 0);
+ my $soft_core_genes = ($self->gene_category_count->{soft_core} ? $self->gene_category_count->{soft_core} : 0);
+ my $shell_genes =($self->gene_category_count->{shell} ? $self->gene_category_count->{shell} : 0);
+ my $cloud_genes = ($self->gene_category_count->{cloud} ? $self->gene_category_count->{cloud} : 0);
+ my $total_genes = $core_genes + $soft_core_genes + $shell_genes + $cloud_genes ;
+
+ $self->logger->warn("Very few core genes detected with the current settings. Try modifying the core definition ( -cd 90 ) and/or
+ the blast identity (-i 70) parameters. Also try checking for contamination (-qc) and ensure you only have one species.") if($core_genes < 100);
+
+ print {$fh} "Core genes\t($core_percentage".'% <= strains <= 100%)'."\t$core_genes\n";
+ print {$fh} "Soft core genes\t(".$shell_percentage."% <= strains < ".$soft_core_percentage."%)\t$soft_core_genes\n";
+ print {$fh} "Shell genes\t(".$cloud_percentage."% <= strains < ".$shell_percentage."%)\t$shell_genes\n";
+ print {$fh} "Cloud genes\t(0% <= strains < ".$cloud_percentage."%)\t$cloud_genes\n";
+ print {$fh} "Total genes\t(0% <= strains <= 100%)\t$total_genes\n";
+
+ close($fh);
+ return 1;
+}
+
+sub _build_gene_category_count {
+ my ($self) = @_;
+ my %gene_category_count;
+ $self->_soft_core_percentage($self->core_definition);
+
+ if ( $self->_soft_core_percentage <= $self->_shell_percentage ) {
+ $self->_shell_percentage( $self->_soft_core_percentage - 0.01 );
+ }
+
+ my $number_of_samples = keys %{ $self->sample_names_to_column_index };
+ for my $gene_name ( keys %{ $self->_genes_to_rows } ) {
+ my $isolates_with_gene = 0;
+
+ for ( my $i = $self->_num_fixed_headers ; $i < @{ $self->_genes_to_rows->{$gene_name} } ; $i++ ) {
+ $isolates_with_gene++
+ if ( defined( $self->_genes_to_rows->{$gene_name}->[$i] ) && $self->_genes_to_rows->{$gene_name}->[$i] ne "" );
+ }
+
+ if ( $isolates_with_gene < $self->_cloud_percentage() * $number_of_samples ) {
+ $gene_category_count{cloud}++;
+ }
+ elsif ( $isolates_with_gene < $self->_shell_percentage() * $number_of_samples ) {
+ $gene_category_count{shell}++;
+ }
+ elsif ( $isolates_with_gene < $self->_soft_core_percentage() * $number_of_samples ) {
+ $gene_category_count{soft_core}++;
+ }
+ else {
+ $gene_category_count{core}++;
+ }
+ }
+ return \%gene_category_count;
+}
+
+sub _build_ordered_genes {
+ my ($self) = @_;
+ return Bio::Roary::ExtractCoreGenesFromSpreadsheet->new( spreadsheet => $self->spreadsheet, core_definition => $self->core_definition )
+ ->ordered_core_genes();
+}
+
+sub _build__genes_to_rows {
+ my ($self) = @_;
+
+ my %genes_to_rows;
+ seek( $self->_input_spreadsheet_fh, 0, 0 );
+ my $header_row = $self->_csv_parser->getline( $self->_input_spreadsheet_fh );
+ $self->_populate_sample_names_to_column_index($header_row);
+
+ while ( my $row = $self->_csv_parser->getline( $self->_input_spreadsheet_fh ) ) {
+ next if ( !defined( $row->[0] ) || $row->[0] eq "" );
+ $genes_to_rows{ $row->[0] } = $row;
+ }
+
+ return \%genes_to_rows;
+}
+
+sub _populate_sample_names_to_column_index {
+ my ( $self, $row ) = @_;
+
+ my %samples_to_index;
+ for ( my $i = $self->_num_fixed_headers ; $i < @{$row} ; $i++ ) {
+ next if ( ( !defined( $row->[$i] ) ) || $row->[$i] eq "" );
+ $samples_to_index{ $row->[$i] } = $i;
+ }
+ $self->sample_names_to_column_index( \%samples_to_index );
+}
+
+sub _build_all_sample_statistics {
+ my ($self) = @_;
+
+ my %sample_stats;
+
+ # For each sample - loop over genes in order - number of contiguous blocks - max size of contiguous block - n50 - incorrect joins
+ for my $sample_name ( sort keys %{ $self->sample_names_to_column_index } ) {
+ $sample_stats{$sample_name} = $self->_sample_statistics($sample_name);
+ }
+ return \%sample_stats;
+}
+
+sub _sample_statistics {
+ my ( $self, $sample_name ) = @_;
+
+ my $sample_column_index = $self->sample_names_to_column_index->{$sample_name};
+ my @gene_ids;
+ for my $gene_name ( @{ $self->ordered_genes } ) {
+ my $sample_gene_id = $self->_genes_to_rows->{$gene_name}->[$sample_column_index];
+ next unless ( defined($sample_gene_id) );
+
+ if ( $sample_gene_id =~ /_([\d]+)$/ ) {
+ my $gene_number = $1;
+ push( @gene_ids, $gene_number );
+ }
+ else {
+ next;
+ }
+ }
+
+ return $self->_number_of_contiguous_blocks( \@gene_ids );
+}
+
+sub _number_of_contiguous_blocks {
+ my ( $self, $gene_ids ) = @_;
+
+ my $current_gene_id = $gene_ids->[0];
+ my $number_of_blocks = 1;
+ my $largest_block_size = 0;
+ my $block_size = 0;
+ for my $gene_id ( @{$gene_ids} ) {
+ if ( !( ( $current_gene_id + $self->contiguous_window >= $gene_id ) && ( $current_gene_id - $self->contiguous_window <= $gene_id ) )
+ )
+ {
+ if ( $block_size >= $largest_block_size ) {
+ $largest_block_size = $block_size;
+ $block_size = 0;
+ }
+ $number_of_blocks++;
+ }
+ $current_gene_id = $gene_id;
+ $block_size++;
+ }
+
+ if ( $block_size > $largest_block_size ) {
+ $largest_block_size = $block_size;
+ }
+ return { num_blocks => $number_of_blocks, largest_block_size => $largest_block_size };
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
+
diff --git a/lib/Bio/Roary/BedFromGFFRole.pm b/lib/Bio/Roary/BedFromGFFRole.pm
new file mode 100644
index 0000000..8dc926e
--- /dev/null
+++ b/lib/Bio/Roary/BedFromGFFRole.pm
@@ -0,0 +1,71 @@
+package Bio::Roary::BedFromGFFRole;
+
+# ABSTRACT: A role to create a bed file from a gff
+
+=head1 SYNOPSIS
+
+ A role to create a bed file from a gff
+ with 'Bio::Roary::BedFromGFFRole';
+
+=cut
+
+use Moose::Role;
+use Bio::Tools::GFF;
+
+has '_tags_to_filter' => ( is => 'ro', isa => 'Str', default => '(CDS|ncRNA|tRNA|tmRNA|rRNA)' );
+has 'min_gene_size_in_nucleotides' => ( is => 'ro', isa => 'Int', default => 120 );
+has 'output_directory' => ( is => 'ro', isa => 'Str', default => '.' );
+
+sub _bed_output_filename {
+ my ($self) = @_;
+ return join('/',($self->output_directory,join( '.', ( $self->output_filename, 'intermediate.bed' ) )));
+}
+
+sub _create_bed_file_from_gff {
+ my ($self) = @_;
+
+ open( my $bed_fh, '>', $self->_bed_output_filename );
+ my $gffio = Bio::Tools::GFF->new( -file => $self->gff_file, -gff_version => 3 );
+ while ( my $feature = $gffio->next_feature() ) {
+
+ next unless defined($feature);
+
+ # Only interested in a few tags
+ my $tags_regex = $self->_tags_to_filter;
+ next if !( $feature->primary_tag =~ /$tags_regex/ );
+
+ # Must have an ID tag
+ my $gene_id = $self->_get_feature_id($feature);
+ next unless($gene_id);
+
+ #filter out small genes
+ next if ( ( $feature->end - $feature->start ) < $self->min_gene_size_in_nucleotides );
+
+ my $strand = ($feature->strand > 0)? '+':'-' ;
+ print {$bed_fh} join( "\t", ( $feature->seq_id, $feature->start -1, $feature->end, $gene_id, 1, $strand ) ) . "\n";
+ }
+ $gffio->close();
+}
+
+sub _get_feature_id
+{
+ my ($self, $feature) = @_;
+ my ( $gene_id, @junk ) ;
+ if ( $feature->has_tag('ID') )
+ {
+ ( $gene_id, @junk ) = $feature->get_tag_values('ID');
+ }
+ elsif($feature->has_tag('locus_tag'))
+ {
+ ( $gene_id, @junk ) = $feature->get_tag_values('locus_tag');
+ }
+ else
+ {
+ return undef;
+ }
+ $gene_id =~ s!["']!!g;
+ return undef if ( $gene_id eq "" );
+ return $gene_id ;
+}
+
+1;
diff --git a/lib/Bio/Roary/ChunkFastaFile.pm b/lib/Bio/Roary/ChunkFastaFile.pm
new file mode 100644
index 0000000..0fcfabb
--- /dev/null
+++ b/lib/Bio/Roary/ChunkFastaFile.pm
@@ -0,0 +1,77 @@
+package Bio::Roary::ChunkFastaFile;
+
+# ABSTRACT: Take in a FASTA file and chunk it up into smaller pieces.
+
+=head1 SYNOPSIS
+
+Take in a FASTA file and chunk it up into smaller pieces.
+ use Bio::Roary::ChunkFastaFile;
+
+ my $obj = Bio::Roary::ChunkFastaFile->new(
+ fasta_file => 'abc.fa',
+ );
+ $obj->sequence_file_names;
+
+=cut
+
+use Moose;
+use Bio::SeqIO;
+use Bio::Roary::Exceptions;
+use Cwd;
+use File::Temp;
+
+has 'fasta_file' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'target_chunk_size' => ( is => 'ro', isa => 'Int', default => 200000 );
+has 'sequence_file_names' => ( is => 'ro', isa => 'ArrayRef', lazy => 1, builder => '_build_sequence_file_names' );
+has '_working_directory' =>
+ ( is => 'ro', isa => 'File::Temp::Dir', default => sub { File::Temp->newdir( DIR => getcwd, CLEANUP => 1 ); } );
+has '_working_directory_name' => ( is => 'ro', isa => 'Str', lazy => 1, builder => '_build__working_directory_name' );
+has '_input_seqio' => ( is => 'ro', isa => 'Bio::SeqIO', lazy => 1, builder => '_build__input_seqio' );
+
+sub _build__working_directory_name {
+ my ($self) = @_;
+ return $self->_working_directory->dirname();
+}
+
+sub _build__input_seqio {
+ my ($self) = @_;
+ return Bio::SeqIO->new( -file => $self->fasta_file, -format => 'Fasta' );
+}
+
+sub _create_next_chunk_file_name {
+ my ( $self, $chunk_number ) = @_;
+ return join( '/', ( $self->_working_directory_name, $chunk_number . '.seq' ) );
+}
+
+sub _create_next_chunk_seqio {
+ my ( $self, $chunk_number ) = @_;
+ return Bio::SeqIO->new( -file => ">".$self->_create_next_chunk_file_name($chunk_number), -format => 'Fasta' );
+}
+
+sub _build_sequence_file_names {
+ my ($self) = @_;
+ my @sequence_file_names;
+ my $chunk_number = 0;
+ my $current_chunk_length = 0;
+ my $current_chunk_seqio = $self->_create_next_chunk_seqio($chunk_number);
+ push( @sequence_file_names, $self->_create_next_chunk_file_name($chunk_number) );
+
+ while ( my $input_seq = $self->_input_seqio->next_seq() ) {
+ if ( $current_chunk_length > $self->target_chunk_size ) {
+
+ # next chunk
+ $chunk_number++;
+ $current_chunk_length = 0;
+ $current_chunk_seqio = $self->_create_next_chunk_seqio($chunk_number);
+ push( @sequence_file_names, $self->_create_next_chunk_file_name($chunk_number) );
+ }
+ $current_chunk_seqio->write_seq($input_seq);
+ $current_chunk_length += $input_seq->length();
+ }
+ return \@sequence_file_names;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/ClustersRole.pm b/lib/Bio/Roary/ClustersRole.pm
new file mode 100644
index 0000000..9cb295b
--- /dev/null
+++ b/lib/Bio/Roary/ClustersRole.pm
@@ -0,0 +1,70 @@
+package Bio::Roary::ClustersRole;
+# ABSTRACT: A role to read a clusters file from CD hit
+
+=head1 SYNOPSIS
+
+A role to read a clusters file from CD hit
+ with 'Bio::Roary::ClustersRole';
+
+=cut
+
+use Moose::Role;
+use Bio::Roary::Exceptions;
+
+has 'clusters_filename' => ( is => 'ro', isa => 'Str', required => 1 );
+has '_clustered_genes' => ( is => 'ro',lazy => 1, builder => '_build__clustered_genes' );
+has '_clusters_fh' => ( is => 'ro',lazy => 1, builder => '_build__clusters_fh' );
+
+sub _build__clusters_fh
+{
+ my($self) = @_;
+ open(my $fh, $self->clusters_filename) or Bio::Roary::Exceptions::FileNotFound->throw( error => 'Cant open file: ' . $self->clusters_filename );
+ return $fh;
+}
+
+sub _build__clustered_genes
+{
+ my($self) = @_;
+ my $fh = $self->_clusters_fh;
+ my %clustered_genes ;
+
+ my %raw_clusters;
+ my $current_cluster_name;
+ while(<$fh>)
+ {
+ my $line = $_;
+ if($line =~ /^>(.+)$/)
+ {
+ $current_cluster_name = $1;
+ }
+
+ #>Cluster 5
+ #0 4201aa, >6630_4#9_00008... *
+ #1 4201aa, >6631_1#23_00379... at 100.00%
+
+ if($line =~ /[\d]+\t[\w]+, >(.+)\.\.\. (.+)$/)
+ {
+ my $gene_name = $1;
+ my $identity = $2;
+
+ if($identity eq '*')
+ {
+ $raw_clusters{$current_cluster_name}{representative_gene_name} = $gene_name;
+ }
+ else
+ {
+ push(@{$raw_clusters{$current_cluster_name}{gene_names}}, $gene_name);
+ }
+ }
+ }
+
+ # iterate over the raw clusters and convert to a simple hash
+ for my $cluster_name (keys %raw_clusters)
+ {
+ $clustered_genes{$raw_clusters{$cluster_name}{representative_gene_name}} = $raw_clusters{$cluster_name}{gene_names};
+ }
+
+ return \%clustered_genes;
+}
+
+1;
\ No newline at end of file
diff --git a/lib/Bio/Roary/CombinedProteome.pm b/lib/Bio/Roary/CombinedProteome.pm
new file mode 100644
index 0000000..89e1a66
--- /dev/null
+++ b/lib/Bio/Roary/CombinedProteome.pm
@@ -0,0 +1,51 @@
+package Bio::Roary::CombinedProteome;
+
+# ABSTRACT: Take in multiple FASTA sequences containing proteomes and concat them together and output a FASTA file, filtering out more than 5% X's
+
+=head1 SYNOPSIS
+
+Take in multiple FASTA sequences containing proteomes and concat them together and output a FASTA file, filtering out more than 5% X's
+ use Bio::Roary::CombinedProteome;
+
+ my $obj = Bio::Roary::CombinedProteome->new(
+ proteome_files => ['abc.fa','efg.fa'],
+ output_filename => 'example_output.fa',
+ maximum_percentage_of_unknowns => 5.0,
+ );
+ $obj->create_combined_proteome_file;
+
+=cut
+
+use Moose;
+use Bio::Roary::Exceptions;
+
+has 'proteome_files' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'output_filename' => ( is => 'ro', isa => 'Str', default => 'combined_output.fa' );
+
+sub BUILD {
+ my ($self) = @_;
+
+ for my $filename ( @{ $self->proteome_files } ) {
+ Bio::Roary::Exceptions::FileNotFound->throw( error => 'Cant open file: ' . $filename )
+ unless ( -e $filename );
+ }
+}
+
+
+
+sub create_combined_proteome_file {
+ my ($self) = @_;
+
+ unlink($self->output_filename);
+ for my $filename (@{$self->proteome_files })
+ {
+ system(join(' ', ("cat", $filename, ">>", $self->output_filename)));
+ }
+
+ 1;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/CommandLine/AssemblyStatistics.pm b/lib/Bio/Roary/CommandLine/AssemblyStatistics.pm
new file mode 100644
index 0000000..5562c65
--- /dev/null
+++ b/lib/Bio/Roary/CommandLine/AssemblyStatistics.pm
@@ -0,0 +1,134 @@
+undef $VERSION;
+package Bio::Roary::CommandLine::AssemblyStatistics;
+
+# ABSTRACT: Given a spreadsheet of gene presence and absense calculate some statistics
+
+=head1 SYNOPSIS
+
+Given a spreadsheet of gene presence and absense calculate some statistics
+
+=cut
+
+use Moose;
+use Getopt::Long qw(GetOptionsFromArray);
+use Bio::Roary::AssemblyStatistics;
+extends 'Bio::Roary::CommandLine::Common';
+
+has 'args' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'script_name' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'help' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'spreadsheet' => ( is => 'rw', isa => 'Str', default => 'gene_presence_absence.csv' );
+has 'job_runner' => ( is => 'rw', isa => 'Str', default => 'Local' );
+has 'cpus' => ( is => 'rw', isa => 'Int', default => 1 );
+has 'output_filename' => ( is => 'rw', isa => 'Str', default => 'assembly_statistics.csv' );
+has 'version' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'core_definition' => ( is => 'rw', isa => 'Num', default => 0.99 );
+has 'verbose' => ( is => 'rw', isa => 'Bool', default => 0 );
+
+
+sub BUILD {
+ my ($self) = @_;
+
+ my (
+ $spreadsheet,
+ $job_runner,
+ $cpus,
+ $output_filename,
+ $version,
+ $core_definition,
+ $verbose,
+ $help
+ );
+
+ GetOptionsFromArray(
+ $self->args,
+ 'o|output_filename=s' => \$output_filename,
+ 'j|job_runner=s' => \$job_runner,
+ 'p|processors=i' => \$cpus,
+ 'cd|core_definition=f' => \$core_definition,
+ 'v|verbose' => \$verbose,
+ 'w|version' => \$version,
+ 'h|help' => \$help,
+ );
+
+ $self->version($version) if ( defined($version) );
+ if ( $self->version ) {
+ die($self->_version());
+ }
+
+ if ( defined($verbose) ) {
+ $self->verbose($verbose);
+ $self->logger->level(10000);
+ }
+
+ $self->help($help) if ( defined($help) );
+ ( !$self->help ) or die $self->usage_text;
+ if(@{$self->args} == 0)
+ {
+ $self->logger->error("Error: You need to provide a gene_presence_absence.csv spreadsheet");
+ die $self->usage_text;
+ }
+ $self->output_filename($output_filename) if ( defined($output_filename) );
+ $self->job_runner($job_runner) if ( defined($job_runner) );
+ $self->cpus($cpus) if ( defined($cpus) );
+
+ if ( $self->cpus > 1 ) {
+ $self->job_runner('Parallel');
+ }
+
+ $self->core_definition( $core_definition / 100 ) if ( defined($core_definition) );
+
+ for my $filename ( @{ $self->args } ) {
+ if ( !-e $filename ) {
+ $self->logger->error("Error: Cant access file $filename");
+ die $self->usage_text;
+ }
+ }
+ $self->spreadsheet( $self->args->[0] );
+
+}
+
+sub _version
+{
+ my ($self) = @_;
+ if(defined($Bio::Roary::CommandLine::AssemblyStatistics::VERSION))
+ {
+ return $Bio::Roary::CommandLine::AssemblyStatistics::VERSION ."\n";
+ }
+ else
+ {
+ return "x.y.z\n";
+ }
+}
+
+sub run {
+ my ($self) = @_;
+
+ my $obj = Bio::Roary::AssemblyStatistics->new( spreadsheet => $self->spreadsheet, logger => $self->logger );
+ $obj->create_summary_output;
+}
+
+sub usage_text {
+ my ($self) = @_;
+
+ return <<USAGE;
+Usage: pan_genome_assembly_statistics [options] gene_presence_absence.csv
+Take in a gene presence and absence spreadsheet and output some statistics
+
+Options: -p INT number of threads [1]
+ -o STR output filename [assembly_statistics.csv]
+ -cd FLOAT percentage of isolates a gene must be in to be core [99]
+ -v verbose output to STDOUT
+ -w print version and exit
+ -h this help message
+
+Example: Run with defaults
+ pan_genome_assembly_statistics gene_presence_absence.csv
+
+For further information see: http://sanger-pathogens.github.io/Roary/
+USAGE
+}
+
+__PACKAGE__->meta->make_immutable;
+no Moose;
+1;
diff --git a/lib/Bio/Roary/CommandLine/Common.pm b/lib/Bio/Roary/CommandLine/Common.pm
new file mode 100644
index 0000000..9db65f5
--- /dev/null
+++ b/lib/Bio/Roary/CommandLine/Common.pm
@@ -0,0 +1,57 @@
+package Bio::Roary::CommandLine::Common;
+# ABSTRACT: Common command line settings
+
+=head1 SYNOPSIS
+
+Common command line settings
+
+ extends 'Bio::Roary::CommandLine::Common';
+
+=cut
+
+use Moose;
+use FindBin;
+use Log::Log4perl qw(:easy);
+
+has 'logger' => ( is => 'ro', lazy => 1, builder => '_build_logger');
+has 'version' => ( is => 'rw', isa => 'Bool', default => 0 );
+
+sub _build_logger
+{
+ my ($self) = @_;
+ Log::Log4perl->easy_init(level => $ERROR);
+ my $logger = get_logger();
+ return $logger;
+}
+
+
+sub run {
+ my ($self) = @_;
+}
+
+sub usage_text {
+ my ($self) = @_;
+ return "Usage text";
+}
+
+sub _version {
+ my ($self) = @_;
+ return "x.y.z\n";
+}
+
+
+# add our included binaries to the END of the PATH
+before 'run' => sub {
+ my ($self) = @_;
+ my $OPSYS = $^O;
+ my $BINDIR = "$FindBin::RealBin/../binaries/$OPSYS";
+
+ for my $dir ($BINDIR, $FindBin::RealBin) {
+ if (-d $dir) {
+ $ENV{PATH} .= ":$dir";
+ }
+ }
+};
+
+no Moose;
+1;
\ No newline at end of file
diff --git a/lib/Bio/Roary/CommandLine/CreatePanGenome.pm b/lib/Bio/Roary/CommandLine/CreatePanGenome.pm
new file mode 100644
index 0000000..4fe32d8
--- /dev/null
+++ b/lib/Bio/Roary/CommandLine/CreatePanGenome.pm
@@ -0,0 +1,72 @@
+undef $VERSION;
+package Bio::Roary::CommandLine::CreatePanGenome;
+
+# ABSTRACT: Take in FASTA files of proteins and cluster them
+
+=head1 SYNOPSIS
+
+Take in FASTA files of proteins and cluster them
+
+=cut
+
+use Moose;
+use Getopt::Long qw(GetOptionsFromArray);
+use Bio::Roary;
+use Bio::Roary::PrepareInputFiles;
+use Bio::Roary::QC::Report;
+extends 'Bio::Roary::CommandLine::Roary';
+
+has 'job_runner' => ( is => 'rw', isa => 'Str', default => 'Local' );
+has 'output_multifasta_files' => ( is => 'rw', isa => 'Bool', default => 1 );
+has 'dont_create_rplots' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'core_definition' => ( is => 'rw', isa => 'Num', default => 0.99 );
+has 'run_qc' => ( is => 'rw', isa => 'Bool', default => 1 );
+
+sub usage_text {
+ my ($self) = @_;
+
+ return <<USAGE;
+Usage: create_pan_genome [options] *.gff
+Build a pan genome with WTSI defaults.
+
+Options: -p INT number of threads [1]
+ -o STR clusters output filename [clustered_proteins]
+ -f STR output directory [.]
+ -e create a multiFASTA alignment of core genes
+ -n fast core gene alignement with MAFFT, use with -e
+ -i minimum percentage identity for blastp [95]
+ -cd FLOAT percentage of isolates a gene must be in to be core [99]
+ -z dont delete intermediate files
+ -t INT translation table [11]
+ -v verbose output to STDOUT
+ -y add gene inference information to spreadsheet, doesnt work with -e
+ -g INT maximum number of clusters [50000]
+ -qc generate QC report with Kraken
+ -k STR path to Kraken database for QC, use with -qc
+ -w print version and exit
+ -a check dependancies and print versions
+ -h this help message
+
+Example: Quickly generate a core gene alignment using 16 threads
+
+ bsub.py --threads 16 10 log create_pan_genome -e --mafft -p 16 *.gff
+
+Example: Allow Roary to bsub the jobs to LSF - you cant bsub this command itself
+
+ create_pan_genome -j LSF -e --mafft -p 16 *.gff
+
+Example: Create a tree and visualise with iCANDY
+
+ annotationfind –t file –i file_of_lanes -symlink .
+ bsub.py --threads 16 10 log create_pan_genome -e --mafft -p 16 *.gff
+ ~sh16/scripts/run_RAxML.py -a core_gene_alignment.aln -q normal -M 8 -n 8 -V AVX -o tree
+ bsub.py 10 log ~sh16/scripts/iCANDY.py -t RAxML_bipartitions.tree -q taxa -l 1 -E 30 -o accessory.pdf -M -L left -p A1 -g 90 accessory.tab accessory.header.embl
+
+For further info see: http://mediawiki.internal.sanger.ac.uk/index.php/Pathogen_Informatics_Pan_Genome_Pipeline
+
+USAGE
+}
+
+__PACKAGE__->meta->make_immutable;
+no Moose;
+1;
diff --git a/lib/Bio/Roary/CommandLine/ExtractProteomeFromGff.pm b/lib/Bio/Roary/CommandLine/ExtractProteomeFromGff.pm
new file mode 100644
index 0000000..e80eab5
--- /dev/null
+++ b/lib/Bio/Roary/CommandLine/ExtractProteomeFromGff.pm
@@ -0,0 +1,121 @@
+undef $VERSION;
+package Bio::Roary::CommandLine::ExtractProteomeFromGff;
+
+# ABSTRACT: Take in GFF files and output the proteome
+
+=head1 SYNOPSIS
+
+Take in a GFF file and output the proteome
+
+=cut
+
+use Moose;
+use Getopt::Long qw(GetOptionsFromArray);
+use Bio::Roary::ExtractProteomeFromGFF;
+use File::Basename;
+extends 'Bio::Roary::CommandLine::Common';
+
+has 'args' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'script_name' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'help' => ( is => 'rw', isa => 'Bool', default => 0 );
+
+has 'gff_files' => ( is => 'rw', isa => 'ArrayRef' );
+has 'output_suffix' => ( is => 'rw', isa => 'Str', default => 'proteome.faa' );
+has '_error_message' => ( is => 'rw', isa => 'Str' );
+has 'apply_unknowns_filter' => ( is => 'rw', isa => 'Bool', default => 1 );
+has 'translation_table' => ( is => 'rw', isa => 'Int', default => 11 );
+has 'verbose' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'output_directory' => ( is => 'rw', isa => 'Str', default => '.' );
+
+sub BUILD {
+ my ($self) = @_;
+
+ my ( $gff_files, $output_suffix, $apply_unknowns_filter, $help, $translation_table, $verbose, $cmd_version, $output_directory );
+
+ GetOptionsFromArray(
+ $self->args,
+ 'o|output_suffix=s' => \$output_suffix,
+ 'f|apply_unknowns_filter=i' => \$apply_unknowns_filter,
+ 't|translation_table=i' => \$translation_table,
+ 'v|verbose' => \$verbose,
+ 'd|output_directory=s' => \$output_directory,
+ 'w|version' => \$cmd_version,
+ 'h|help' => \$help,
+ );
+
+ if ( defined($verbose) ) {
+ $self->verbose($verbose);
+ $self->logger->level(10000);
+ }
+
+ $self->help($help) if(defined($help));
+ ( !$self->help ) or die $self->usage_text;
+
+ $self->version($cmd_version) if ( defined($cmd_version) );
+ if ( $self->version ) {
+ die($self->_version());
+ }
+
+ if ( @{ $self->args } == 0 ) {
+ $self->_error_message("Error: You need to provide a GFF file");
+ }
+
+ $self->output_suffix($output_suffix) if ( defined($output_suffix) ) ;
+ $self->apply_unknowns_filter($apply_unknowns_filter) if ( defined($apply_unknowns_filter) );
+ $self->translation_table($translation_table) if ( defined($translation_table) );
+ $self->output_directory($output_directory) if ( defined($output_directory) );
+
+ for my $filename ( @{ $self->args } ) {
+ if ( !-e $filename ) {
+ $self->_error_message("Error: Cant access file $filename");
+ last;
+ }
+ }
+ $self->gff_files( $self->args );
+
+}
+
+sub run {
+ my ($self) = @_;
+
+ if ( defined( $self->_error_message ) ) {
+ print $self->_error_message . "\n";
+ die $self->usage_text;
+ }
+
+ for my $gff_file ( @{ $self->gff_files } ) {
+ my ( $filename, $directories, $suffix ) = fileparse($gff_file);
+ my $obj = Bio::Roary::ExtractProteomeFromGFF->new(
+ gff_file => $gff_file,
+ output_filename => $filename . '.' . $self->output_suffix,
+ apply_unknowns_filter => $self->apply_unknowns_filter,
+ translation_table => $self->translation_table,
+ output_directory => $self->output_directory,
+ );
+ $obj->fasta_file();
+ }
+
+}
+
+sub usage_text {
+ my ($self) = @_;
+
+ return <<USAGE;
+Usage: extract_proteome_from_gff [options] *.gff
+Take in GFF files and create FASTA files of the protein sequences
+
+Options: -o STR output suffix [proteome.faa]
+ -t INT translation table [11]
+ -f filter sequences with missing data
+ -v verbose output to STDOUT
+ -d STR output directory
+ -w print version and exit
+ -h this help message
+
+For further info see: http://sanger-pathogens.github.io/Roary/
+USAGE
+}
+
+__PACKAGE__->meta->make_immutable;
+no Moose;
+1;
diff --git a/lib/Bio/Roary/CommandLine/GeneAlignmentFromNucleotides.pm b/lib/Bio/Roary/CommandLine/GeneAlignmentFromNucleotides.pm
new file mode 100644
index 0000000..f929629
--- /dev/null
+++ b/lib/Bio/Roary/CommandLine/GeneAlignmentFromNucleotides.pm
@@ -0,0 +1,134 @@
+undef $VERSION;
+package Bio::Roary::CommandLine::GeneAlignmentFromNucleotides;
+
+# ABSTRACT: Take in a multifasta file of nucleotides, convert to proteins and align with PRANK
+
+=head1 SYNOPSIS
+
+Take in a multifasta file of nucleotides, convert to proteins and align with PRANK or MAFFT, reverse translate back to nucleotides
+
+=cut
+
+use Moose;
+use Getopt::Long qw(GetOptionsFromArray);
+use File::Copy;
+use Bio::Roary::AnnotateGroups;
+use Bio::Roary::External::Prank;
+use Bio::Roary::Output::GroupsMultifastaProtein;
+use Bio::Roary::SortFasta;
+use Bio::Roary::External::Mafft;
+extends 'Bio::Roary::CommandLine::Common';
+
+has 'args' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'script_name' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'help' => ( is => 'rw', isa => 'Bool', default => 0 );
+
+has 'nucleotide_fasta_files' => ( is => 'rw', isa => 'ArrayRef' );
+has '_error_message' => ( is => 'rw', isa => 'Str' );
+has 'verbose' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'mafft' => ( is => 'rw', isa => 'Bool', default => 0 );
+has '_min_similarity' => ( is => 'rw', isa => 'Num', default => 0.98 );
+
+sub BUILD {
+ my ($self) = @_;
+
+ my ( $nucleotide_fasta_files, $help, $verbose,$mafft, );
+
+ GetOptionsFromArray(
+ $self->args,
+ 'v|verbose' => \$verbose,
+ 'n|mafft' => \$mafft,
+ 'h|help' => \$help,
+ );
+
+ if ( defined($verbose) ) {
+ $self->verbose($verbose);
+ $self->logger->level(10000);
+ }
+ $self->mafft($mafft) if (defined($mafft));
+ $self->help($help) if ( defined($help) );
+ if ( @{ $self->args } == 0 ) {
+ $self->_error_message("Error: You need to provide at least 1 FASTA file");
+ }
+
+ for my $filename ( @{ $self->args } ) {
+ if ( !-e $filename ) {
+ $self->_error_message("Error: Cant access file $filename");
+ last;
+ }
+ }
+ $self->nucleotide_fasta_files( $self->args );
+}
+
+sub run {
+ my ($self) = @_;
+
+ ( !$self->help ) or die $self->usage_text;
+ if ( defined( $self->_error_message ) ) {
+ print $self->_error_message . "\n";
+ die $self->usage_text;
+ }
+
+ for my $fasta_file ( @{ $self->nucleotide_fasta_files } ) {
+
+ my $sort_fasta_before = Bio::Roary::SortFasta->new(
+ input_filename => $fasta_file,
+ make_multiple_of_three => 1,
+ );
+ $sort_fasta_before->sort_fasta->replace_input_with_output_file;
+
+ if ( $sort_fasta_before->sequences_unaligned == 1 || $sort_fasta_before->sequences_unaligned == 0 && $sort_fasta_before->similarity <= $self->_min_similarity) {
+
+ if ( $self->mafft == 1 ) {
+ my $mafft_obj = Bio::Roary::External::Mafft->new(
+ input_filename => $fasta_file,
+ output_filename => $fasta_file . '.aln',
+ job_runner => 'Local',
+ logger => $self->logger,
+ verbose => $self->verbose
+ );
+ $mafft_obj->run();
+ }
+ else {
+
+ my $prank_obj = Bio::Roary::External::Prank->new(
+ input_filename => $fasta_file,
+ output_filename => $fasta_file . '.aln',
+ job_runner => 'Local',
+ logger => $self->logger,
+ verbose => $self->verbose
+ );
+ $prank_obj->run();
+ }
+ }
+ else {
+ move( $fasta_file, $fasta_file . '.aln' );
+ }
+
+ my $sort_fasta_after_revtrans = Bio::Roary::SortFasta->new(
+ input_filename => $fasta_file . '.aln',
+ remove_nnn_from_end => 1,
+ );
+ $sort_fasta_after_revtrans->sort_fasta->replace_input_with_output_file;
+ unlink($fasta_file);
+ }
+}
+
+sub usage_text {
+ my ($self) = @_;
+
+ return <<USAGE;
+Usage: protein_alignment_from_nucleotides [options] *.fa
+Take in multi-FASTA files of nucleotides and align each file with PRANK or MAFFT
+
+Options: -n nucleotide alignment with MAFFT
+ -v verbose output to STDOUT
+ -h this help message
+
+For further info see: http://sanger-pathogens.github.io/Roary/
+USAGE
+}
+
+__PACKAGE__->meta->make_immutable;
+no Moose;
+1;
diff --git a/lib/Bio/Roary/CommandLine/IterativeCdhit.pm b/lib/Bio/Roary/CommandLine/IterativeCdhit.pm
new file mode 100644
index 0000000..eef7966
--- /dev/null
+++ b/lib/Bio/Roary/CommandLine/IterativeCdhit.pm
@@ -0,0 +1,119 @@
+undef $VERSION;
+package Bio::Roary::CommandLine::IterativeCdhit;
+
+# ABSTRACT: Iteratively run cdhit
+
+=head1 SYNOPSIS
+
+Iteratively run cdhit
+
+=cut
+
+use Moose;
+use Getopt::Long qw(GetOptionsFromArray);
+use Bio::Roary::IterativeCdhit;
+extends 'Bio::Roary::CommandLine::Common';
+
+has 'args' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'script_name' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'help' => ( is => 'rw', isa => 'Bool', default => 0 );
+has '_error_message' => ( is => 'rw', isa => 'Str' );
+
+has 'output_cd_hit_filename' => ( is => 'rw', isa => 'Str', default => '_clustered' );
+has 'output_combined_filename' => ( is => 'rw', isa => 'Str', default => '_combined_files' );
+has 'number_of_input_files' => ( is => 'rw', isa => 'Int', default => 1 );
+has 'output_filtered_clustered_fasta' => ( is => 'rw', isa => 'Str', default => '_clustered_filtered.fa' );
+
+has 'lower_bound_percentage' => ( is => 'rw', isa => 'Num', default => 0.98 );
+has 'upper_bound_percentage' => ( is => 'rw', isa => 'Num', default => 0.99 );
+has 'step_size_percentage' => ( is => 'rw', isa => 'Num', default => 0.005 );
+has 'cpus' => ( is => 'rw', isa => 'Int', default => 1 );
+has 'verbose' => ( is => 'rw', isa => 'Bool', default => 0 );
+
+
+sub BUILD {
+ my ($self) = @_;
+
+ my ( $output_cd_hit_filename,$cpus,$lower_bound_percentage,$upper_bound_percentage,$step_size_percentage, $output_combined_filename, $number_of_input_files, $output_filtered_clustered_fasta,$verbose,
+ $help );
+
+ GetOptionsFromArray(
+ $self->args,
+ 'c|output_cd_hit_filename=s' => \$output_cd_hit_filename,
+ 'm|output_combined_filename=s' => \$output_combined_filename,
+ 'n|number_of_input_files=i' => \$number_of_input_files,
+ 'f|output_filtered_clustered_fasta=s' => \$output_filtered_clustered_fasta,
+ 'l|lower_bound_percentage=s' => \$lower_bound_percentage,
+ 'u|upper_bound_percentage=s' => \$upper_bound_percentage,
+ 's|step_size_percentage=s' => \$step_size_percentage,
+ 'p|cpus=i' => \$cpus,
+ 'v|verbose' => \$verbose,
+ 'h|help' => \$help,
+ );
+
+ if ( defined($verbose) ) {
+ $self->verbose($verbose);
+ $self->logger->level(10000);
+ }
+ $self->help($help) if(defined($help));
+ $self->lower_bound_percentage($lower_bound_percentage/100) if ( defined($lower_bound_percentage) );
+ $self->upper_bound_percentage($upper_bound_percentage/100) if ( defined($upper_bound_percentage) );
+ $self->step_size_percentage($step_size_percentage/100) if ( defined($step_size_percentage) );
+ $self->output_cd_hit_filename($output_cd_hit_filename) if ( defined($output_cd_hit_filename) );
+ $self->output_combined_filename($output_combined_filename) if ( defined($output_combined_filename) );
+ $self->number_of_input_files($number_of_input_files) if ( defined($number_of_input_files) );
+ $self->cpus($cpus) if ( defined($cpus) );
+ $self->output_filtered_clustered_fasta($output_filtered_clustered_fasta)
+ if ( defined($output_filtered_clustered_fasta) );
+
+}
+
+sub run {
+ my ($self) = @_;
+
+ ( !$self->help ) or die $self->usage_text;
+ if ( defined( $self->_error_message ) ) {
+ print $self->_error_message . "\n";
+ die $self->usage_text;
+ }
+
+ my $obj = Bio::Roary::IterativeCdhit->new(
+ output_cd_hit_filename => $self->output_cd_hit_filename,
+ output_combined_filename => $self->output_combined_filename,
+ number_of_input_files => $self->number_of_input_files,
+ output_filtered_clustered_fasta => $self->output_filtered_clustered_fasta,
+ lower_bound_percentage => $self->lower_bound_percentage,
+ upper_bound_percentage => $self->upper_bound_percentage,
+ step_size_percentage => $self->step_size_percentage,
+ cpus => $self->cpus,
+ logger => $self->logger
+
+ );
+ $obj->run;
+}
+
+sub usage_text {
+ my ($self) = @_;
+
+ return <<USAGE;
+Usage: iterative_cdhit [options]
+Iteratively cluster a set of proteins with CD-hit, lower the threshold each time and extracting core genes (1 per isolate) to another file, and remove them from the input proteins file.
+
+Options: -p INT number of threads [1]
+ -m STR output filename for combined proteins [_combined_files]
+ -n INT number of isolates [1]
+ -c STR cd-hit output filename [_clustered]
+ -f STR output filename for filtered sequences [_clustered_filtered.fa]
+ -l FLOAT lower bound percentage identity [98.0]
+ -u FLOAT upper bound percentage identity [99.0]
+ -s FLOAT step size for percentage identity [0.5]
+ -v verbose output to STDOUT
+ -h this help message
+
+For further info see: http://sanger-pathogens.github.io/Roary/
+USAGE
+}
+
+__PACKAGE__->meta->make_immutable;
+no Moose;
+1;
diff --git a/lib/Bio/Roary/CommandLine/ParallelAllAgainstAllBlastp.pm b/lib/Bio/Roary/CommandLine/ParallelAllAgainstAllBlastp.pm
new file mode 100644
index 0000000..6a5de8b
--- /dev/null
+++ b/lib/Bio/Roary/CommandLine/ParallelAllAgainstAllBlastp.pm
@@ -0,0 +1,141 @@
+undef $VERSION;
+package Bio::Roary::CommandLine::ParallelAllAgainstAllBlastp;
+
+# ABSTRACT: Take in a FASTA file of proteins and blast against itself
+
+=head1 SYNOPSIS
+
+Take in a FASTA file of proteins and blast against itself
+
+=cut
+
+use Moose;
+use Getopt::Long qw(GetOptionsFromArray);
+use Bio::Roary::ParallelAllAgainstAllBlast;
+use Bio::Roary::CombinedProteome;
+use Bio::Roary::PrepareInputFiles;
+extends 'Bio::Roary::CommandLine::Common';
+
+has 'args' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'script_name' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'help' => ( is => 'rw', isa => 'Bool', default => 0 );
+
+has 'fasta_files' => ( is => 'rw', isa => 'ArrayRef' );
+has 'output_filename' => ( is => 'rw', isa => 'Str', default => 'blast_results' );
+has 'job_runner' => ( is => 'rw', isa => 'Str', default => 'Local' );
+has 'cpus' => ( is => 'rw', isa => 'Int', default => 1 );
+has 'makeblastdb_exec' => ( is => 'rw', isa => 'Str', default => 'makeblastdb' );
+has 'blastp_exec' => ( is => 'rw', isa => 'Str', default => 'blastp' );
+has 'verbose' => ( is => 'rw', isa => 'Bool', default => 0 );
+
+has '_error_message' => ( is => 'rw', isa => 'Str' );
+
+sub BUILD {
+ my ($self) = @_;
+
+ my ( $fasta_files, $output_filename, $job_runner, $makeblastdb_exec, $blastp_exec, $help, $cpus, $verbose, );
+
+ GetOptionsFromArray(
+ $self->args,
+ 'o|output=s' => \$output_filename,
+ 'j|job_runner=s' => \$job_runner,
+ 'm|makeblastdb_exec=s' => \$makeblastdb_exec,
+ 'b|blastp_exec=s' => \$blastp_exec,
+ 'p|processors=i' => \$cpus,
+ 'v|verbose' => \$verbose,
+ 'h|help' => \$help,
+ );
+
+ if ( @{ $self->args } == 0 ) {
+ $self->_error_message("Error: You need to provide a FASTA file");
+ }
+
+ if ( defined($verbose) ) {
+ $self->verbose($verbose);
+ $self->logger->level(10000);
+ }
+ $self->help($help) if(defined($help));
+ $self->output_filename($output_filename) if ( defined($output_filename) );
+ $self->makeblastdb_exec($makeblastdb_exec) if ( defined($makeblastdb_exec) );
+ $self->blastp_exec($blastp_exec) if ( defined($blastp_exec) );
+ $self->job_runner($job_runner) if ( defined($job_runner) );
+ $self->cpus($cpus) if ( defined($cpus) );
+ if ( $self->cpus > 1 ) {
+ $self->job_runner('Parallel');
+ }
+
+ for my $filename ( @{ $self->args } ) {
+ if ( !-e $filename ) {
+ $self->_error_message("Error: Cant access file $filename");
+ last;
+ }
+ }
+ $self->fasta_files( $self->args );
+
+}
+
+sub run {
+ my ($self) = @_;
+
+ ( !$self->help ) or die $self->usage_text;
+ if ( defined( $self->_error_message ) ) {
+ print $self->_error_message . "\n";
+ die $self->usage_text;
+ }
+
+ my $prepare_input_files = Bio::Roary::PrepareInputFiles->new(
+ input_files => $self->fasta_files,
+ );
+
+ my $output_combined_filename;
+ if(@{$self->fasta_files} > 1)
+ {
+ $output_combined_filename = 'combined_files.fa';
+ $self->logger->info("Combining protein files");
+ my $combine_fasta_files = Bio::Roary::CombinedProteome->new(
+ proteome_files => $prepare_input_files->fasta_files,
+ output_filename => $output_combined_filename,
+ maximum_percentage_of_unknowns => 5.0,
+ apply_unknowns_filter => 0
+ );
+ $combine_fasta_files->create_combined_proteome_file;
+ }
+ else
+ {
+ $output_combined_filename = $self->fasta_files->[0];
+ }
+
+ $self->logger->info("Beginning all against all blast");
+ my $blast_obj = Bio::Roary::ParallelAllAgainstAllBlast->new(
+ fasta_file => $output_combined_filename,
+ blast_results_file_name => $self->output_filename,
+ job_runner => $self->job_runner,
+ cpus => $self->cpus,
+ makeblastdb_exec => $self->makeblastdb_exec,
+ blastp_exec => $self->blastp_exec,
+ logger => $self->logger
+ );
+ $blast_obj->run();
+}
+
+sub usage_text {
+ my ($self) = @_;
+
+ return <<USAGE;
+Usage: parallel_all_against_all_blastp [options] file.faa
+Take in a FASTA file of proteins and blast against itself
+
+Options: -p INT number of threads [1]
+ -o STR output filename for blast results [blast_results]
+ -m STR makeblastdb executable [makeblastdb]
+ -b STR blastp executable [blastp]
+ -v verbose output to STDOUT
+ -h this help message
+
+For further info see: http://sanger-pathogens.github.io/Roary/
+USAGE
+}
+
+__PACKAGE__->meta->make_immutable;
+no Moose;
+1;
diff --git a/lib/Bio/Roary/CommandLine/QueryRoary.pm b/lib/Bio/Roary/CommandLine/QueryRoary.pm
new file mode 100644
index 0000000..ee11ee7
--- /dev/null
+++ b/lib/Bio/Roary/CommandLine/QueryRoary.pm
@@ -0,0 +1,253 @@
+undef $VERSION;
+package Bio::Roary::CommandLine::QueryRoary;
+
+# ABSTRACT: Take in a groups file and the protein fasta files and output selected data
+
+=head1 SYNOPSIS
+
+Take in a groups file and the protein fasta files and output selected data
+
+=cut
+
+use Moose;
+use Getopt::Long qw(GetOptionsFromArray);
+use Bio::Roary::AnalyseGroups;
+use Bio::Roary::Output::GroupsMultifastas;
+use Bio::Roary::Output::QueryGroups;
+use Bio::Roary::PrepareInputFiles;
+use Bio::Roary::Output::DifferenceBetweenSets;
+use Bio::Roary::AnnotateGroups;
+use Bio::Roary::GroupStatistics;
+use Bio::Roary::OrderGenes;
+extends 'Bio::Roary::CommandLine::Common';
+
+has 'args' => ( is => 'rw', isa => 'ArrayRef', required => 1 );
+has 'script_name' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'help' => ( is => 'rw', isa => 'Bool', default => 0 );
+
+has 'input_files' => ( is => 'rw', isa => 'ArrayRef' );
+has 'groups_filename' => ( is => 'rw', isa => 'Str', default => 'clustered_proteins');
+has 'group_names' => ( is => 'rw', isa => 'ArrayRef' );
+has 'input_set_one' => ( is => 'rw', isa => 'ArrayRef' );
+has 'input_set_two' => ( is => 'rw', isa => 'ArrayRef' );
+has 'output_filename' => ( is => 'rw', isa => 'Str', default => 'pan_genome_results' );
+has 'action' => ( is => 'rw', isa => 'Str', default => 'union' );
+has 'core_definition' => ( is => 'rw', isa => 'Num', default => 0.99 );
+has 'verbose' => ( is => 'rw', isa => 'Bool', default => 0 );
+
+has '_error_message' => ( is => 'rw', isa => 'Str' );
+
+sub BUILD {
+ my ($self) = @_;
+
+ my ( $input_files, $output_filename, $groups_filename, @group_names, @input_set_one, @input_set_two, $action, $core_definition,$verbose, $help );
+
+ GetOptionsFromArray(
+ $self->args,
+ 'o|output=s' => \$output_filename,
+ 'g|groups_filename=s' => \$groups_filename,
+ 'n|group_names=s' => \@group_names,
+ 'a|action=s' => \$action,
+ 'i|input_set_one=s' => \@input_set_one,
+ 't|input_set_two=s' => \@input_set_two,
+ 'c|core_definition=f' => \$core_definition,
+ 'v|verbose' => \$verbose,
+ 'h|help' => \$help,
+ );
+
+ if ( defined($verbose) ) {
+ $self->verbose($verbose);
+ $self->logger->level(10000);
+ }
+ $self->help($help) if(defined($help));
+
+ $self->output_filename($output_filename) if ( defined($output_filename) );
+ $self->action($action) if ( defined($action) );
+ $self->core_definition( $core_definition / 100 ) if ( defined($core_definition) );
+ if ( defined($groups_filename) && ( -e $groups_filename ) ) {
+ $self->groups_filename($groups_filename);
+ }
+
+ if(! (-e $self->groups_filename)) {
+ $self->_error_message("Error: Cant access the groups file: ".$self->groups_filename);
+ }
+
+ @group_names = split( /,/, join( ',', @group_names ) );
+ $self->group_names( \@group_names ) if (@group_names);
+
+ @input_set_one = split( /,/, join( ',', @input_set_one ) );
+ $self->input_set_one( \@input_set_one ) if (@input_set_one);
+
+ @input_set_two = split( /,/, join( ',', @input_set_two ) );
+ $self->input_set_two( \@input_set_two ) if (@input_set_two);
+
+ if(defined($self->input_set_one) && defined($self->input_set_two) )
+ {
+ my @all_input_files = (@{ $self->input_set_one },@{ $self->input_set_two });
+ $self->args(\@all_input_files);
+ }
+
+
+ if ( !defined($self->input_set_two) && @{ $self->args } == 0) {
+ $self->_error_message("Error: You need to provide a FASTA file");
+ }
+
+ for my $filename ( @{ $self->args } ) {
+ if ( !-e $filename ) {
+ $self->_error_message("Error: Cant access file $filename");
+ last;
+ }
+ }
+ $self->input_files( $self->args );
+
+}
+
+sub run {
+ my ($self) = @_;
+
+ ( !$self->help ) or die $self->usage_text;
+ if ( defined( $self->_error_message ) ) {
+ print $self->_error_message . "\n";
+ die $self->usage_text;
+ }
+
+ my $prepare_input_files = Bio::Roary::PrepareInputFiles->new(
+ input_files => $self->input_files,
+ );
+
+ my $analyse_groups_obj = Bio::Roary::AnalyseGroups->new(
+ fasta_files => $prepare_input_files->fasta_files,
+ groups_filename => $self->groups_filename,
+ );
+
+ if ( $self->action eq 'union' ) {
+ my $query_groups = Bio::Roary::Output::QueryGroups->new(
+ analyse_groups => $analyse_groups_obj,
+ output_union_filename => $self->output_filename,
+ input_filenames => $prepare_input_files->fasta_files
+ );
+ $query_groups->groups_union();
+ }
+ elsif ( $self->action eq 'intersection' ) {
+ my $query_groups = Bio::Roary::Output::QueryGroups->new(
+ analyse_groups => $analyse_groups_obj,
+ output_intersection_filename => $self->output_filename,
+ input_filenames => $prepare_input_files->fasta_files,
+ core_definition => $self->core_definition
+ );
+ $query_groups->groups_intersection();
+ }
+ elsif ( $self->action eq 'complement' ) {
+ my $query_groups = Bio::Roary::Output::QueryGroups->new(
+ analyse_groups => $analyse_groups_obj,
+ output_complement_filename => $self->output_filename,
+ input_filenames => $prepare_input_files->fasta_files,
+ core_definition => $self->core_definition
+ );
+ $query_groups->groups_complement();
+ }
+ elsif ( $self->action eq 'gene_multifasta' && defined( $self->group_names ) ) {
+ my $group_multi_fastas = Bio::Roary::Output::GroupsMultifastas->new(
+ group_names => $self->group_names,
+ analyse_groups => $analyse_groups_obj,
+ output_filename_base => $self->output_filename
+ );
+ $group_multi_fastas->create_files();
+ }
+ elsif($self->action eq 'difference' && defined($self->input_set_one) && defined($self->input_set_two))
+ {
+ my $difference_between_sets = Bio::Roary::Output::DifferenceBetweenSets->new(
+ analyse_groups => $analyse_groups_obj,
+ input_filenames_sets => [
+ $prepare_input_files->lookup_fasta_files_from_unknown_input_files($self->input_set_one),
+ $prepare_input_files->lookup_fasta_files_from_unknown_input_files($self->input_set_two)
+ ],
+ );
+ $difference_between_sets->groups_set_one_unique();
+ $difference_between_sets->groups_set_two_unique();
+ $difference_between_sets->groups_in_common();
+
+ for my $differences_group_filename(($difference_between_sets->groups_set_one_unique_filename,$difference_between_sets->groups_set_two_unique_filename,$difference_between_sets->groups_in_common_filename))
+ {
+ $self->create_spreadsheets($differences_group_filename, $prepare_input_files->fasta_files, $self->input_files);
+ }
+
+ }
+ else {
+ print "Nothing done\n";
+ }
+}
+
+sub create_spreadsheets
+{
+ my ($self, $groups_file, $fasta_files, $gff_files) = @_;
+
+ my $analyse_groups_obj = Bio::Roary::AnalyseGroups->new(
+ fasta_files => $fasta_files,
+ groups_filename => $groups_file,
+ );
+
+ my $annotate_groups = Bio::Roary::AnnotateGroups->new(
+ gff_files => $gff_files,
+ output_filename => $groups_file.'_reannotated',
+ groups_filename => $groups_file,
+ );
+ $annotate_groups->reannotate;
+
+ my $order_genes_obj = Bio::Roary::OrderGenes->new(
+ analyse_groups_obj => $analyse_groups_obj,
+ gff_files => $gff_files,
+ core_definition => $self->core_definition,
+ pan_graph_filename => 'set_difference_core_accessory_graph.dot',
+ accessory_graph_filename => 'set_difference_accessory_graph.dot',
+ );
+
+ my $group_statistics = Bio::Roary::GroupStatistics->new(
+ output_filename => $groups_file.'_statistics.csv',
+ annotate_groups_obj => $annotate_groups,
+ analyse_groups_obj => $analyse_groups_obj,
+ groups_to_contigs => $order_genes_obj->groups_to_contigs
+ );
+ $group_statistics->create_spreadsheet;
+}
+
+sub usage_text {
+ my ($self) = @_;
+
+ return <<USAGE;
+Usage: query_pan_genome [options] *.gff
+Perform set operations on the pan genome to see the gene differences between groups of isolates.
+
+Options: -g STR groups filename [clustered_proteins]
+ -a STR action (union/intersection/complement/gene_multifasta/difference) [union]
+ -c FLOAT percentage of isolates a gene must be in to be core [99]
+ -o STR output filename [pan_genome_results]
+ -n STR comma separated list of gene names for use with gene_multifasta action
+ -i STR comma separated list of filenames, comparison set one
+ -t STR comma separated list of filenames, comparison set two
+ -v verbose output to STDOUT
+ -h this help message
+
+Examples:
+Union of genes found in isolates
+ query_pan_genome -a union *.gff
+
+Intersection of genes found in isolates (core genes)
+ query_pan_genome -a intersection *.gff
+
+Complement of genes found in isolates (accessory genes)
+ query_pan_genome -a complement *.gff
+
+Extract the sequence of each gene listed and create multi-FASTA files
+ query_pan_genome -a gene_multifasta -n gryA,mecA,abc *.gff
+
+Gene differences between sets of isolates
+ query_pan_genome -a difference --input_set_one 1.gff,2.gff --input_set_two 3.gff,4.gff,5.gff
+
+For further info see: http://sanger-pathogens.github.io/Roary/
+USAGE
+}
+
+__PACKAGE__->meta->make_immutable;
+no Moose;
+1;
diff --git a/lib/Bio/Roary/CommandLine/Roary.pm b/lib/Bio/Roary/CommandLine/Roary.pm
new file mode 100644
index 0000000..103c0b9
--- /dev/null
+++ b/lib/Bio/Roary/CommandLine/Roary.pm
@@ -0,0 +1,356 @@
+undef $VERSION;
+
+package Bio::Roary::CommandLine::Roary;
+
+# ABSTRACT: Take in FASTA files of proteins and cluster them
+
+=head1 SYNOPSIS
+
+Take in FASTA files of proteins and cluster them
+
+=cut
+
+use Moose;
+use Getopt::Long qw(GetOptionsFromArray);
+use Bio::Roary;
+use Bio::Roary::PrepareInputFiles;
+use Bio::Roary::QC::Report;
+use Bio::Roary::ReformatInputGFFs;
+use Bio::Roary::External::CheckTools;
+use File::Which;
+use File::Path qw(make_path);
+use Cwd qw(abs_path getcwd);
+use File::Temp;
+extends 'Bio::Roary::CommandLine::Common';
+
+has 'args' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'script_name' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'help' => ( is => 'rw', isa => 'Bool', default => 0 );
+
+has 'fasta_files' => ( is => 'rw', isa => 'ArrayRef', default => sub { [] } );
+has 'output_filename' => ( is => 'rw', isa => 'Str', default => 'clustered_proteins' );
+has 'output_directory' => ( is => 'rw', isa => 'Str', default => '.' );
+has '_original_directory' => ( is => 'rw', isa => 'Str', default => '.' );
+has 'job_runner' => ( is => 'rw', isa => 'Str', default => 'Local' );
+has 'makeblastdb_exec' => ( is => 'rw', isa => 'Str', default => 'makeblastdb' );
+has 'blastp_exec' => ( is => 'rw', isa => 'Str', default => 'blastp' );
+has 'mcxdeblast_exec' => ( is => 'rw', isa => 'Str', default => 'mcxdeblast' );
+has 'mcl_exec' => ( is => 'rw', isa => 'Str', default => 'mcl' );
+has 'apply_unknowns_filter' => ( is => 'rw', isa => 'Bool', default => 1 );
+has 'cpus' => ( is => 'rw', isa => 'Int', default => 1 );
+has 'output_multifasta_files' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'perc_identity' => ( is => 'rw', isa => 'Num', default => 95 );
+has 'dont_delete_files' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'dont_create_rplots' => ( is => 'rw', isa => 'Bool', default => 1 );
+has 'dont_run_qc' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'dont_split_groups' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'verbose_stats' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'translation_table' => ( is => 'rw', isa => 'Int', default => 11 );
+has 'mafft' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'group_limit' => ( is => 'rw', isa => 'Num', default => 50000 );
+has 'core_definition' => ( is => 'rw', isa => 'Num', default => 0.99 );
+has 'verbose' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'kraken_db' => ( is => 'rw', isa => 'Str', default => '/lustre/scratch108/pathogen/pathpipe/kraken/minikraken_20140330/' );
+has 'run_qc' => ( is => 'rw', isa => 'Bool', default => 0 );
+has '_working_directory' => ( is => 'rw', isa => 'File::Temp::Dir', lazy => 1, builder => '_build__working_directory' );
+
+sub _build__working_directory
+{
+ my ($self) = @_;
+ return File::Temp->newdir( DIR => getcwd, CLEANUP => 1 );
+}
+
+sub BUILD {
+ my ($self) = @_;
+
+ my (
+ $fasta_files, $verbose, $create_rplots, $group_limit, $dont_run_qc,
+ $max_threads, $dont_delete_files, $dont_split_groups, $perc_identity, $output_filename,
+ $job_runner, $makeblastdb_exec, $mcxdeblast_exec, $mcl_exec, $blastp_exec,
+ $apply_unknowns_filter, $cpus, $output_multifasta_files, $verbose_stats, $translation_table,
+ $run_qc, $core_definition, $help, $kraken_db, $cmd_version,
+ $mafft, $output_directory, $check_dependancies,
+ );
+
+ GetOptionsFromArray(
+ $self->args,
+ 'o|output=s' => \$output_filename,
+ 'f|output_directory=s' => \$output_directory,
+ 'j|job_runner=s' => \$job_runner,
+ 'm|makeblastdb_exec=s' => \$makeblastdb_exec,
+ 'b|blastp_exec=s' => \$blastp_exec,
+ 'd|mcxdeblast_exec=s' => \$mcxdeblast_exec,
+ 'c|mcl_exec=s' => \$mcl_exec,
+ 'p|processors=i' => \$cpus,
+ 'u|apply_unknowns_filter=i' => \$apply_unknowns_filter,
+ 'e|output_multifasta_files' => \$output_multifasta_files,
+ 'i|perc_identity=i' => \$perc_identity,
+ 'z|dont_delete_files' => \$dont_delete_files,
+ 's|dont_split_groups' => \$dont_split_groups,
+ 'r|create_rplots' => \$create_rplots,
+ 'y|verbose_stats' => \$verbose_stats,
+ 't|translation_table=i' => \$translation_table,
+ 'g|group_limit=i' => \$group_limit,
+ 'qc|run_qc' => \$run_qc,
+ 'x|dont_run_qc' => \$dont_run_qc,
+ 'cd|core_definition=f' => \$core_definition,
+ 'v|verbose' => \$verbose,
+ 'n|mafft' => \$mafft,
+ 'k|kraken_db=s' => \$kraken_db,
+ 'w|version' => \$cmd_version,
+ 'a|check_dependancies' => \$check_dependancies,
+ 'h|help' => \$help,
+ );
+
+ $self->version($cmd_version) if ( defined($cmd_version) );
+ if ( $self->version ) {
+ print $self->_version() ;
+ return;
+ }
+
+ print "\nPlease cite Roary if you use any of the results it produces:
+ Andrew J. Page, Carla A. Cummins, Martin Hunt, Vanessa K. Wong, Sandra Reuter, Matthew T. G. Holden, Maria Fookes, Daniel Falush, Jacqueline A. Keane, Julian Parkhill,
+ \"Roary: Rapid large-scale prokaryote pan genome analysis\", Bioinformatics, 2015 Nov 15;31(22):3691-3693
+ doi: http://doi.org/10.1093/bioinformatics/btv421
+ Pubmed: 26198102\n\n";
+
+ $self->help($help) if ( defined($help) );
+ if( $self->help )
+ {
+ print $self->usage_text;
+ return;
+ }
+
+ if ($check_dependancies) {
+ my $check_tools = Bio::Roary::External::CheckTools->new();
+ $check_tools->check_all_tools;
+ $self->logger->error( "Roary version " . $self->_version() );
+ }
+
+ if ( defined($verbose) ) {
+ $self->verbose($verbose);
+ $self->logger->level(10000);
+ }
+
+ if ( @{ $self->args } < 2 ) {
+ $self->logger->error("Error: You need to provide at least 2 files to build a pan genome");
+ die $self->usage_text;
+ }
+ $self->output_filename($output_filename) if ( defined($output_filename) );
+ $self->job_runner($job_runner) if ( defined($job_runner) );
+ $self->makeblastdb_exec($makeblastdb_exec) if ( defined($makeblastdb_exec) );
+ $self->blastp_exec($blastp_exec) if ( defined($blastp_exec) );
+ $self->mcxdeblast_exec($mcxdeblast_exec) if ( defined($mcxdeblast_exec) );
+ $self->mcl_exec($mcl_exec) if ( defined($mcl_exec) );
+ $self->cpus($cpus) if ( defined($cpus) );
+
+ if ( defined($perc_identity) ) {
+ $self->perc_identity($perc_identity);
+ if ( $perc_identity < 50 ) {
+ $self->logger->error(
+"The percentage identity is too low. Either somethings wrong with your data, like contamination, or your doing something that the software isnt designed to support."
+ );
+ }
+ }
+
+ $self->mafft($mafft) if ( defined($mafft) );
+ $self->apply_unknowns_filter($apply_unknowns_filter)
+ if ( defined($apply_unknowns_filter) );
+
+ if ( defined($output_multifasta_files) ) {
+ if ( which('prank') ) {
+ $self->output_multifasta_files($output_multifasta_files);
+ }
+ else {
+
+ if ( which('mafft') ) {
+ $self->output_multifasta_files($output_multifasta_files);
+ $self->mafft(1);
+ $self->logger->warn("PRANK not found in your PATH so using MAFFT instead to generate multiFASTA alignments.");
+ }
+ else {
+ $self->logger->warn("PRANK (or MAFFT) not found in your PATH so cannot generate multiFASTA alignments, skipping for now.");
+ }
+ }
+ }
+ $self->dont_delete_files($dont_delete_files) if ( defined($dont_delete_files) );
+ $self->dont_split_groups($dont_split_groups) if ( defined($dont_split_groups) );
+ $self->dont_create_rplots(0) if ( defined($create_rplots) );
+ $self->verbose_stats($verbose_stats) if ( defined $verbose_stats );
+ $self->translation_table($translation_table) if ( defined($translation_table) );
+ $self->group_limit($group_limit) if ( defined($group_limit) );
+ $self->kraken_db($kraken_db) if ( defined($kraken_db) );
+ $self->output_directory($output_directory) if ( defined($output_directory) );
+
+ if ( defined $verbose_stats && defined($output_multifasta_files) ) {
+ $self->verbose_stats(0);
+ $self->logger->warn("The verbose stats spreadsheet is not compatible with the core gene alignement so disabling verbose_stats");
+ }
+
+ if ( defined($run_qc) ) {
+ if ( which('kraken') && which('kraken-report') ) {
+ $self->run_qc($run_qc);
+ }
+ else {
+ $self->logger->warn("kraken or kraken-report not found in your PATH so cannot run QC, skipping for now.");
+ }
+ }
+
+ if ( $self->cpus > 1 ) {
+ $self->job_runner('Parallel');
+ }
+
+ $self->core_definition( $core_definition / 100 ) if ( defined($core_definition) );
+
+ for my $filename ( @{ $self->args } ) {
+ if ( !-e $filename ) {
+ $self->logger->error("Error: Cant access file $filename");
+ die $self->usage_text;
+ }
+ push( @{ $self->fasta_files }, abs_path($filename) );
+ }
+
+ $self->_working_directory( File::Temp->newdir( DIR => getcwd, CLEANUP => 0 ) ) if ( $self->dont_delete_files );
+}
+
+sub _setup_output_directory {
+ my ($self) = @_;
+ return if ( $self->output_directory eq '.' || $self->output_directory eq '' );
+
+ if ( -e $self->output_directory || -d $self->output_directory ) {
+ $self->logger->warn("Output directory name exists already so adding a timestamp to the end");
+ $self->output_directory( $self->output_directory() . '_' . time() );
+ if ( -e $self->output_directory || -d $self->output_directory ) {
+ die("Output directory name with time stamp exist so giving up");
+ }
+ }
+ make_path( $self->output_directory, { error => \my $err } );
+ if (@$err) {
+ for my $diag (@$err) {
+ my ( $file, $message ) = %$diag;
+ die("Error creating output directory $message");
+ }
+ }
+ $self->logger->info( "Output directory created: " . $self->output_directory );
+
+ $self->_original_directory( getcwd() );
+ chdir( $self->output_directory );
+ return $self;
+}
+
+sub run {
+ my ($self) = @_;
+
+ return if($self->version || $self->help);
+
+ $self->_setup_output_directory;
+
+ $self->logger->info("Fixing input GFF files");
+ my $reformat_input_files = Bio::Roary::ReformatInputGFFs->new( gff_files => $self->fasta_files, logger => $self->logger );
+ $reformat_input_files->fix_duplicate_gene_ids();
+ if ( @{ $reformat_input_files->fixed_gff_files } == 0 ) {
+ die(
+"All input files have been excluded from analysis. Please check you have valid GFF files, with annotation and a FASTA sequence at the end. Better still, reannotate your FASTA file with PROKKA."
+ );
+ }
+ $self->fasta_files( $reformat_input_files->fixed_gff_files );
+
+ $self->logger->info("Extracting proteins from GFF files");
+ my $prepare_input_files = Bio::Roary::PrepareInputFiles->new(
+ input_files => $self->fasta_files,
+ job_runner => $self->job_runner,
+ apply_unknowns_filter => $self->apply_unknowns_filter,
+ cpus => $self->cpus,
+ translation_table => $self->translation_table,
+ verbose => $self->verbose,
+ working_directory => $self->_working_directory,
+
+ );
+
+ if ( $self->run_qc ) {
+ $self->logger->info("Running Kraken on each input assembly");
+ my $qc_input_files = Bio::Roary::QC::Report->new(
+ input_files => $self->fasta_files,
+ job_runner => $self->job_runner,
+ cpus => $self->cpus,
+ verbose => $self->verbose,
+ kraken_db => $self->kraken_db
+ );
+ $qc_input_files->report;
+ }
+
+ my $pan_genome_obj = Bio::Roary->new(
+ input_files => $self->fasta_files,
+ fasta_files => $prepare_input_files->fasta_files,
+ output_filename => $self->output_filename,
+ job_runner => $self->job_runner,
+ cpus => $self->cpus,
+ makeblastdb_exec => $self->makeblastdb_exec,
+ blastp_exec => $self->blastp_exec,
+ output_multifasta_files => $self->output_multifasta_files,
+ perc_identity => $self->perc_identity,
+ dont_delete_files => $self->dont_delete_files,
+ dont_create_rplots => $self->dont_create_rplots,
+ dont_split_groups => $self->dont_split_groups,
+ verbose_stats => $self->verbose_stats,
+ translation_table => $self->translation_table,
+ group_limit => $self->group_limit,
+ core_definition => $self->core_definition,
+ verbose => $self->verbose,
+ mafft => $self->mafft,
+ );
+ $pan_genome_obj->run();
+
+ chdir( $self->_original_directory );
+}
+
+sub _version {
+ my ($self) = @_;
+ if ( defined($Bio::Roary::CommandLine::Roary::VERSION) ) {
+ return $Bio::Roary::CommandLine::Roary::VERSION . "\n";
+ }
+ else {
+ return "x.y.z\n";
+ }
+}
+
+sub usage_text {
+ my ($self) = @_;
+
+ return <<USAGE;
+Usage: roary [options] *.gff
+
+Options: -p INT number of threads [1]
+ -o STR clusters output filename [clustered_proteins]
+ -f STR output directory [.]
+ -e create a multiFASTA alignment of core genes using PRANK
+ -n fast core gene alignment with MAFFT, use with -e
+ -i minimum percentage identity for blastp [95]
+ -cd FLOAT percentage of isolates a gene must be in to be core [99]
+ -qc generate QC report with Kraken
+ -k STR path to Kraken database for QC, use with -qc
+ -a check dependancies and print versions
+ -b STR blastp executable [blastp]
+ -c STR mcl executable [mcl]
+ -d STR mcxdeblast executable [mcxdeblast]
+ -g INT maximum number of clusters [50000]
+ -m STR makeblastdb executable [makeblastdb]
+ -r create R plots, requires R and ggplot2
+ -s dont split paralogs
+ -t INT translation table [11]
+ -z dont delete intermediate files
+ -v verbose output to STDOUT
+ -w print version and exit
+ -y add gene inference information to spreadsheet, doesnt work with -e
+ -h this help message
+
+Example: Quickly generate a core gene alignment using 8 threads
+ roary -e --mafft -p 8 *.gff
+
+For further info see: http://sanger-pathogens.github.io/Roary/
+USAGE
+}
+
+__PACKAGE__->meta->make_immutable;
+no Moose;
+1;
diff --git a/lib/Bio/Roary/CommandLine/RoaryCoreAlignment.pm b/lib/Bio/Roary/CommandLine/RoaryCoreAlignment.pm
new file mode 100644
index 0000000..dc52a60
--- /dev/null
+++ b/lib/Bio/Roary/CommandLine/RoaryCoreAlignment.pm
@@ -0,0 +1,143 @@
+undef $VERSION;
+package Bio::Roary::CommandLine::RoaryCoreAlignment;
+
+# ABSTRACT: Take in the group statistics spreadsheet and the location of the gene multifasta files and create a core alignment.
+
+=head1 SYNOPSIS
+
+Take in the group statistics spreadsheet and the location of the gene multifasta files and create a core alignment.
+
+=cut
+
+use Moose;
+use Getopt::Long qw(GetOptionsFromArray);
+use Cwd 'abs_path';
+use File::Path qw(remove_tree);
+use Bio::Roary::ExtractCoreGenesFromSpreadsheet;
+use Bio::Roary::LookupGeneFiles;
+use Bio::Roary::MergeMultifastaAlignments;
+extends 'Bio::Roary::CommandLine::Common';
+
+has 'args' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'script_name' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'help' => ( is => 'rw', isa => 'Bool', default => 0 );
+
+has 'multifasta_base_directory' => ( is => 'rw', isa => 'Str', default => 'pan_genome_sequences' );
+has 'spreadsheet_filename' => ( is => 'rw', isa => 'Str', default => 'gene_presence_absence.csv' );
+has 'output_filename' => ( is => 'rw', isa => 'Str', default => 'core_gene_alignment.aln' );
+has 'core_definition' => ( is => 'rw', isa => 'Num', default => 0.99 );
+has 'dont_delete_files' => ( is => 'rw', isa => 'Bool', default => 0 );
+has '_error_message' => ( is => 'rw', isa => 'Str' );
+has 'verbose' => ( is => 'rw', isa => 'Bool', default => 0 );
+
+sub BUILD {
+ my ($self) = @_;
+
+ my ( $multifasta_base_directory, $spreadsheet_filename, $output_filename, $core_definition,$verbose, $help, $mafft, $dont_delete_files );
+
+ GetOptionsFromArray(
+ $self->args,
+ 'm|multifasta_base_directory=s' => \$multifasta_base_directory,
+ 's|spreadsheet_filename=s' => \$spreadsheet_filename,
+ 'o|output_filename=s' => \$output_filename,
+ 'cd|core_definition=f' => \$core_definition,
+ 'z|dont_delete_files' => \$dont_delete_files,
+ 'v|verbose' => \$verbose,
+ 'h|help' => \$help,
+ );
+
+ if ( defined($verbose) ) {
+ $self->verbose($verbose);
+ $self->logger->level(10000);
+ }
+ $self->help($help) if(defined($help));
+
+ if ( defined($multifasta_base_directory) && ( -d $multifasta_base_directory ) ) {
+ $self->multifasta_base_directory( abs_path($multifasta_base_directory));
+ }
+ if(! -d $self->multifasta_base_directory )
+ {
+ $self->_error_message("Error: Cant access the multifasta base directory: ".$self->multifasta_base_directory);
+ }
+
+ if ( defined($spreadsheet_filename) && ( -e $spreadsheet_filename ) ) {
+ $self->spreadsheet_filename( abs_path($spreadsheet_filename));
+ }
+ if(! -e $self->spreadsheet_filename )
+ {
+ $self->_error_message("Error: Cant access the spreadsheet: ".$self->spreadsheet_filename);
+ }
+ $self->output_filename( $output_filename ) if ( defined($output_filename) );
+ if ( defined($core_definition) )
+ {
+ if($core_definition > 1)
+ {
+ $self->core_definition( $core_definition/100 );
+ }
+ else
+ {
+ $self->core_definition( $core_definition );
+ }
+ }
+ $self->dont_delete_files($dont_delete_files) if ( defined($dont_delete_files) );
+
+}
+
+sub run {
+ my ($self) = @_;
+
+ ( !$self->help ) or die $self->usage_text;
+ if ( defined( $self->_error_message ) ) {
+ print $self->_error_message . "\n";
+ die $self->usage_text;
+ }
+
+ $self->logger->info("Extract core genes from spreadsheet");
+ my $core_genes_obj = Bio::Roary::ExtractCoreGenesFromSpreadsheet->new(
+ spreadsheet => $self->spreadsheet_filename,
+ core_definition => $self->core_definition
+ );
+
+ $self->logger->info("Looking up genes in files");
+ my $gene_files = Bio::Roary::LookupGeneFiles->new(
+ multifasta_directory => $self->multifasta_base_directory,
+ ordered_genes => $core_genes_obj->ordered_core_genes,
+ );
+
+ $self->logger->info("Merge multifasta alignments");
+ my $merge_alignments_obj = Bio::Roary::MergeMultifastaAlignments->new(
+ sample_names => $core_genes_obj->sample_names,
+ multifasta_files => $gene_files->ordered_gene_files(),
+ output_filename => $self->output_filename,
+ sample_names_to_genes => $core_genes_obj->sample_names_to_genes
+ );
+ $merge_alignments_obj->merge_files;
+
+ if($self->dont_delete_files == 0)
+ {
+ remove_tree('pan_genome_sequences');
+ }
+}
+
+sub usage_text {
+ my ($self) = @_;
+
+ return <<USAGE;
+Usage: pan_genome_core_alignment [options]
+Create an alignment of core genes from the spreadsheet and the directory of gene multi-FASTAs.
+
+Options: -o STR output filename [core_gene_alignment.aln]
+ -cd FLOAT percentage of isolates a gene must be in to be core [99]
+ -m STR directory containing gene multi-FASTAs [pan_genome_sequences]
+ -s STR gene presence and absence spreadsheet [gene_presence_absence.csv]
+ -z dont delete intermediate files
+ -v verbose output to STDOUT
+ -h this help message
+
+For further info see: http://sanger-pathogens.github.io/Roary/
+USAGE
+}
+
+__PACKAGE__->meta->make_immutable;
+no Moose;
+1;
diff --git a/lib/Bio/Roary/CommandLine/RoaryPostAnalysis.pm b/lib/Bio/Roary/CommandLine/RoaryPostAnalysis.pm
new file mode 100644
index 0000000..5206382
--- /dev/null
+++ b/lib/Bio/Roary/CommandLine/RoaryPostAnalysis.pm
@@ -0,0 +1,237 @@
+undef $VERSION;
+package Bio::Roary::CommandLine::RoaryPostAnalysis;
+
+# ABSTRACT: Perform the post analysis on the pan genome
+
+=head1 SYNOPSIS
+
+Perform the post analysis on the pan genome
+
+=cut
+
+use Moose;
+use Getopt::Long qw(GetOptionsFromArray);
+use Bio::Roary::PostAnalysis;
+use File::Find::Rule;
+use Bio::Roary::External::GeneAlignmentFromNucleotides;
+use File::Path qw(remove_tree);
+use Bio::Roary::External::Fasttree;
+extends 'Bio::Roary::CommandLine::Common';
+
+has 'args' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'script_name' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'help' => ( is => 'rw', isa => 'Bool', default => 0 );
+has '_error_message' => ( is => 'rw', isa => 'Str' );
+
+has 'fasta_files' => ( is => 'rw', isa => 'Str', default => '_fasta_files' );
+has 'input_files' => ( is => 'rw', isa => 'Str', default => '_gff_files');
+has 'output_filename' => ( is => 'rw', isa => 'Str', default => 'clustered_proteins' );
+has 'output_pan_geneome_filename' => ( is => 'rw', isa => 'Str', default => 'pan_genome.fa' );
+has 'output_statistics_filename' => ( is => 'rw', isa => 'Str', default => 'gene_presence_absence.csv' );
+has 'output_multifasta_files' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'clusters_filename' => ( is => 'rw', isa => 'Str', default => '_clustered.clstr' );
+has 'job_runner' => ( is => 'rw', isa => 'Str', default => 'Local' );
+has 'cpus' => ( is => 'rw', isa => 'Int', default => 1 );
+has 'dont_delete_files' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'dont_create_rplots' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'dont_split_groups' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'verbose_stats' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'translation_table' => ( is => 'rw', isa => 'Int', default => 11 );
+has 'group_limit' => ( is => 'rw', isa => 'Num', default => 50000 );
+has 'core_definition' => ( is => 'rw', isa => 'Num', default => 0.99 );
+has 'verbose' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'mafft' => ( is => 'rw', isa => 'Bool', default => 0 );
+
+sub BUILD {
+ my ($self) = @_;
+
+ my (
+ $output_filename, $dont_create_rplots, $dont_delete_files, $dont_split_groups, $output_pan_geneome_filename,
+ $job_runner, $output_statistics_filename, $output_multifasta_files, $clusters_filename, $core_definition,
+ $fasta_files, $input_files, $verbose_stats, $translation_table, $help, $cpus,$group_limit,$verbose,$mafft
+ );
+
+
+ GetOptionsFromArray(
+ $self->args,
+ 'o|output=s' => \$output_filename,
+ 'j|job_runner=s' => \$job_runner,
+ 'm|output_multifasta_files' => \$output_multifasta_files,
+ 'p=s' => \$output_pan_geneome_filename,
+ 's=s' => \$output_statistics_filename,
+ 'c=s' => \$clusters_filename,
+ 'f=s' => \$fasta_files,
+ 'i=s' => \$input_files,
+ 'a|dont_delete_files' => \$dont_delete_files,
+ 'b|dont_create_rplots' => \$dont_create_rplots,
+ 'd|dont_split_groups' => \$dont_split_groups,
+ 'e|verbose_stats' => \$verbose_stats,
+ 'z|processors=i' => \$cpus,
+ 't|translation_table=i' => \$translation_table,
+ 'g|group_limit=i' => \$group_limit,
+ 'cd|core_definition=f' => \$core_definition,
+ 'v|verbose' => \$verbose,
+ 'n|mafft' => \$mafft,
+ 'h|help' => \$help,
+ );
+
+ $self->help($help) if(defined($help));
+ $self->job_runner($job_runner) if ( defined($job_runner) );
+ $self->fasta_files($fasta_files) if ( defined($fasta_files) );
+ $self->input_files($input_files) if ( defined($input_files) );
+ $self->output_filename($output_filename) if ( defined($output_filename) );
+ $self->output_pan_geneome_filename($output_pan_geneome_filename) if ( defined($output_pan_geneome_filename) );
+ $self->output_statistics_filename($output_statistics_filename) if ( defined($output_statistics_filename) );
+ $self->output_multifasta_files($output_multifasta_files) if ( defined($output_multifasta_files) );
+ $self->clusters_filename($clusters_filename) if ( defined($clusters_filename) );
+ $self->dont_delete_files($dont_delete_files) if ( defined($dont_delete_files) );
+ $self->dont_create_rplots($dont_create_rplots) if ( defined($dont_create_rplots) );
+ $self->dont_split_groups($dont_split_groups) if ( defined($dont_split_groups) );
+ $self->verbose_stats($verbose_stats) if ( defined($verbose_stats));
+ $self->translation_table($translation_table) if ( defined($translation_table) );
+ $self->cpus($cpus) if ( defined($cpus) );
+ $self->group_limit($group_limit) if ( defined($group_limit) );
+ $self->core_definition( $core_definition/100 ) if ( defined($core_definition) );
+ $self->mafft($mafft) if ( defined($mafft) );
+ if ( defined($verbose) ) {
+ $self->verbose($verbose);
+ $self->logger->level(10000);
+ }
+}
+
+sub run {
+ my ($self) = @_;
+
+ ( !$self->help ) or die $self->usage_text;
+ if ( defined( $self->_error_message ) ) {
+ print $self->_error_message . "\n";
+ die $self->usage_text;
+ }
+
+ my $input_files = $self->_read_file_into_array($self->input_files);
+ my $obj = Bio::Roary::PostAnalysis->new(
+ fasta_files => $self->_read_file_into_array($self->fasta_files) ,
+ input_files => $input_files ,
+ output_filename => $self->output_filename ,
+ output_pan_geneome_filename => $self->output_pan_geneome_filename,
+ output_statistics_filename => $self->output_statistics_filename ,
+ output_multifasta_files => $self->output_multifasta_files ,
+ clusters_filename => $self->clusters_filename ,
+ dont_delete_files => $self->dont_delete_files,
+ dont_create_rplots => $self->dont_create_rplots,
+ dont_split_groups => $self->dont_split_groups,
+ verbose_stats => $self->verbose_stats,
+ group_limit => $self->group_limit,
+ verbose => $self->verbose,
+ cpus => $self->cpus,
+ logger => $self->logger,
+ core_definition => $self->core_definition,
+ );
+ $obj->run();
+
+ if($self->dont_delete_files == 0)
+ {
+ unlink('_inflated_unsplit_mcl_groups');
+ remove_tree('split_groups');
+ }
+
+ if($self->output_multifasta_files == 1)
+ {
+ print "Aligning each cluster\n" if($self->verbose);
+
+ my $job_runner_to_use = $self->job_runner;
+ if($self->_is_lsf_job_runner_available && $self->job_runner eq "LSF")
+ {
+ $job_runner_to_use = $self->job_runner;
+ }
+ else
+ {
+ $job_runner_to_use = 'Local';
+ }
+
+ my $output_gene_files = $self->_find_input_files;
+ my $seg = Bio::Roary::External::GeneAlignmentFromNucleotides->new(
+ fasta_files => $output_gene_files,
+ job_runner => $job_runner_to_use,
+ translation_table => $self->translation_table,
+ core_definition => $self->core_definition,
+ cpus => $self->cpus,
+ verbose => $self->verbose,
+ mafft => $self->mafft,
+ dont_delete_files => $self->dont_delete_files,
+ num_input_files => $#{$input_files},
+ );
+ $seg->run();
+ }
+}
+
+sub _is_lsf_job_runner_available
+{
+ my ($self) = @_;
+ my $rc = eval "require Bio::Roary::JobRunner::LSF; 1;";
+ if(defined($rc) && $rc == 1)
+ {
+ return 1;
+ }
+ else
+ {
+ return 0;
+ }
+}
+
+sub _find_input_files
+{
+ my ($self) = @_;
+ my @files = File::Find::Rule->file()
+ ->name( '*.fa' )
+ ->in('pan_genome_sequences' );
+ return \@files;
+}
+
+sub _read_file_into_array
+{
+ my ($self, $filename) = @_;
+ open(my $in_fh, $filename);
+
+ my @filenames;
+ while(<$in_fh>){
+ chomp;
+ my $line = $_;
+ push(@filenames, $line);
+ }
+ return \@filenames;
+}
+
+sub usage_text {
+ my ($self) = @_;
+
+ return <<USAGE;
+Usage: pan_genome_post_analysis [options]
+Perform the post analysis on the pan genome. This script is usally only called by another script.
+
+Options: -a dont delete intermediate files
+ -b dont create R plots
+ -c STR clusters filename [_clustered.clstr]
+ -cd FLOAT percentage of isolates a gene must be in to be core [0.99]
+ -d dont split groups
+ -e add inference values to gene presence and absence spreadsheet
+ -f STR file of protein filenames [_fasta_files]
+ -g INT maximum number of clusters [50000]
+ -i STR file of GFF filenames [_gff_files]
+ -m core gene alignement with PRANK
+ -n fast core gene alignement with MAFFT instead of PRANK
+ -o STR clusters output filename [clustered_proteins]
+ -p STR output pan genome filename [pan_genome.fa]
+ -s STR output gene presence and absence filename [gene_presence_absence.csv]
+ -t INT translation table [11]
+ -z INT number of threads [1]
+ -v verbose output to STDOUT
+ -h this help message
+
+For further info see: http://sanger-pathogens.github.io/Roary/
+USAGE
+}
+
+__PACKAGE__->meta->make_immutable;
+no Moose;
+1;
diff --git a/lib/Bio/Roary/CommandLine/RoaryReorderSpreadsheet.pm b/lib/Bio/Roary/CommandLine/RoaryReorderSpreadsheet.pm
new file mode 100644
index 0000000..6785a8c
--- /dev/null
+++ b/lib/Bio/Roary/CommandLine/RoaryReorderSpreadsheet.pm
@@ -0,0 +1,100 @@
+undef $VERSION;
+package Bio::Roary::CommandLine::RoaryReorderSpreadsheet;
+
+# ABSTRACT: Take in a tree and a spreadsheet and output a reordered spreadsheet
+
+=head1 SYNOPSIS
+
+Take in a tree and a spreadsheet and output a reordered spreadsheet
+
+=cut
+
+use Moose;
+use Getopt::Long qw(GetOptionsFromArray);
+use Bio::Roary::ReorderSpreadsheet;
+extends 'Bio::Roary::CommandLine::Common';
+
+has 'args' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'script_name' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'help' => ( is => 'rw', isa => 'Bool', default => 0 );
+
+has 'tree_file' => ( is => 'rw', isa => 'Str' );
+has 'spreadsheet_filename' => ( is => 'rw', isa => 'Str', default => 'gene_presence_absence.csv' );
+has 'output_filename' => ( is => 'rw', isa => 'Str', default => 'reordered_spreadsheet.csv' );
+has 'tree_format' => ( is => 'rw', isa => 'Str', default => 'newick' );
+has 'search_strategy' => ( is => 'rw', isa => 'Str', default => 'depth' );
+has 'sortby' => ( is => 'rw', isa => 'Str', default => 'height');
+has 'verbose' => ( is => 'rw', isa => 'Bool', default => 0 );
+
+
+sub BUILD {
+ my ($self) = @_;
+
+ my ( $output_filename, $tree_file,$search_strategy, $sortby, $tree_format, $spreadsheet_filename,$verbose, $help );
+
+ GetOptionsFromArray(
+ $self->args,
+ 'o|output_filename=s' => \$output_filename,
+ 't|tree_file=s' => \$tree_file,
+ 'f|tree_format=s' => \$tree_format,
+ 's|spreadsheet_filename=s' => \$spreadsheet_filename,
+ 'a|search_strategy=s' => \$search_strategy,
+ 'b|sortby=s' => \$sortby,
+ 'v|verbose' => \$verbose,
+ 'h|help' => \$help,
+ );
+
+ if ( defined($verbose) ) {
+ $self->verbose($verbose);
+ $self->logger->level(10000);
+ }
+ $self->help($help) if(defined($help));
+ $self->output_filename($output_filename) if ( defined($output_filename) );
+ $self->tree_file($tree_file) if ( defined($tree_file) );
+ $self->tree_format($tree_format) if ( defined($tree_format) );
+ $self->spreadsheet_filename($spreadsheet_filename) if ( defined($spreadsheet_filename) );
+ $self->sortby($sortby) if ( defined($sortby) );
+ $self->search_strategy($search_strategy) if ( defined($search_strategy) );
+}
+
+sub run {
+ my ($self) = @_;
+ ( defined($self->spreadsheet_filename) && defined($self->tree_file) && ( -e $self->spreadsheet_filename ) && ( -e $self->tree_file ) && ( !$self->help ) ) or die $self->usage_text;
+
+ ($self->sortby eq "height" || $self->sortby eq "creation" || $self->sortby eq "alpha" || $self->sortby eq "revalpha") or die $self->usage_text;
+ ($self->search_strategy eq "breadth" || $self->search_strategy eq "depth") or die $self->usage_text;
+
+ my $obj = Bio::Roary::ReorderSpreadsheet->new(
+ tree_file => $self->tree_file,
+ spreadsheet => $self->spreadsheet_filename,
+ output_filename => $self->output_filename,
+ sortby => $self->sortby,
+ search_strategy => $self->search_strategy
+ );
+ $obj->reorder_spreadsheet();
+
+}
+
+sub usage_text {
+ my ($self) = @_;
+
+ return <<USAGE;
+Usage: pan_genome_reorder_spreadsheet [options] -t tree.newick
+Reorder the columns in the gene presence and absence spreadsheet against a phylogenetic tree.
+
+Options: -t STR tree filename []
+ -o STR output filename [reordered_spreadsheet.csv]
+ -f STR tree format (newick/nexus/nhx/svggraph/tabtree/lintree) [newick]
+ -s STR input gene presence and absence spreadsheet [gene_presence_absence.csv]
+ -a STR search strategy (depth/breadth) [depth]
+ -b STR sorting method (height/creation/alpha/revalpha) [height]
+ -v verbose output to STDOUT
+ -h this help message
+
+For further info see: http://sanger-pathogens.github.io/Roary/
+USAGE
+}
+
+__PACKAGE__->meta->make_immutable;
+no Moose;
+1;
diff --git a/lib/Bio/Roary/CommandLine/TransferAnnotationToGroups.pm b/lib/Bio/Roary/CommandLine/TransferAnnotationToGroups.pm
new file mode 100644
index 0000000..35736ec
--- /dev/null
+++ b/lib/Bio/Roary/CommandLine/TransferAnnotationToGroups.pm
@@ -0,0 +1,108 @@
+undef $VERSION;
+package Bio::Roary::CommandLine::TransferAnnotationToGroups;
+
+# ABSTRACT: Take in a groups file and a set of GFF files and transfer the consensus annotation
+
+=head1 SYNOPSIS
+
+Take in a groups file and a set of GFF files and transfer the consensus annotation
+
+=cut
+
+use Moose;
+use Getopt::Long qw(GetOptionsFromArray);
+use Bio::Roary::AnnotateGroups;
+extends 'Bio::Roary::CommandLine::Common';
+
+
+has 'args' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'script_name' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'help' => ( is => 'rw', isa => 'Bool', default => 0 );
+
+has 'gff_files' => ( is => 'rw', isa => 'ArrayRef' );
+has 'groups_filename' => ( is => 'rw', isa => 'Str' );
+has 'output_filename' => ( is => 'rw', isa => 'Str', default => 'reannotated_groups' );
+has 'verbose' => ( is => 'rw', isa => 'Bool', default => 0 );
+has '_error_message' => ( is => 'rw', isa => 'Str' );
+
+sub BUILD {
+ my ($self) = @_;
+
+ my ( $gff_files, $output_filename, $groups_filename, @group_names, $action,$verbose, $help );
+
+ GetOptionsFromArray(
+ $self->args,
+ 'o|output=s' => \$output_filename,
+ 'g|groups_filename=s' => \$groups_filename,
+ 'v|verbose' => \$verbose,
+ 'h|help' => \$help,
+ );
+
+ if ( defined($verbose) ) {
+ $self->verbose($verbose);
+ $self->logger->level(10000);
+ }
+
+ $self->help($help) if(defined($help));
+ ( !$self->help ) or die $self->usage_text;
+
+ if ( @{ $self->args } == 0 ) {
+ $self->_error_message("Error: You need to provide a FASTA file");
+ }
+
+ $self->output_filename($output_filename) if ( defined($output_filename) );
+ if ( defined($groups_filename) && ( -e $groups_filename ) ) {
+ $self->groups_filename($groups_filename);
+ }
+ else {
+ $self->_error_message("Error: Cant access the groups file");
+ }
+
+ for my $filename ( @{ $self->args } ) {
+ if ( !-e $filename ) {
+ $self->_error_message("Error: Cant access file $filename");
+ last;
+ }
+ }
+ $self->gff_files( $self->args );
+
+}
+
+sub run {
+ my ($self) = @_;
+
+
+ if ( defined( $self->_error_message ) ) {
+ print $self->_error_message . "\n";
+ die $self->usage_text;
+ }
+
+
+ my $obj = Bio::Roary::AnnotateGroups->new(
+ gff_files => $self->gff_files,
+ output_filename => $self->output_filename,
+ groups_filename => $self->groups_filename,
+ );
+ $obj->reannotate;
+
+}
+
+sub usage_text {
+ my ($self) = @_;
+
+ return <<USAGE;
+Usage: transfer_annotation_to_groups [options] *.gff
+Take in a groups file and the protein fasta files and output selected data
+
+Options: -o STR output filename [reannotated_groups]
+ -g STR clusters filename [clustered_proteins]
+ -v verbose output to STDOUT
+ -h this help message
+
+For further info see: http://sanger-pathogens.github.io/Roary/
+USAGE
+}
+
+__PACKAGE__->meta->make_immutable;
+no Moose;
+1;
diff --git a/lib/Bio/Roary/ContigsToGeneIDsFromGFF.pm b/lib/Bio/Roary/ContigsToGeneIDsFromGFF.pm
new file mode 100644
index 0000000..a2cc6f8
--- /dev/null
+++ b/lib/Bio/Roary/ContigsToGeneIDsFromGFF.pm
@@ -0,0 +1,145 @@
+package Bio::Roary::ContigsToGeneIDsFromGFF;
+
+# ABSTRACT: Parse a GFF and efficiently and extract ordered gene ids on each contig
+
+=head1 SYNOPSIS
+
+Parse a GFF and efficiently and extract ordered gene ids on each contig
+ use Bio::Roary::ContigsToGeneIDsFromGFF;
+
+ my $obj = Bio::Roary::ContigsToGeneIDsFromGFF->new(
+ gff_file => 'abc.gff'
+ );
+ $obj->contig_to_ids;
+
+=cut
+
+use Moose;
+use Bio::Tools::GFF;
+with 'Bio::Roary::ParseGFFAnnotationRole';
+
+has 'contig_to_ids' => ( is => 'rw', isa => 'HashRef', lazy => 1, builder => '_build_contig_to_ids');
+
+has 'overlapping_hypothetical_protein_ids' => ( is => 'ro', isa => 'HashRef', lazy => 1, builder => '_build_overlapping_hypothetical_protein_ids');
+has '_genes_annotation' => ( is => 'rw', isa => 'ArrayRef', default => sub{[]});
+
+has '_min_nucleotide_overlap_percentage' => ( is => 'ro', isa => 'Int', default => 10);
+
+# Manually parse the GFF file because the BioPerl module is too slow
+sub _build_contig_to_ids
+{
+ my ($self) = @_;
+ my %contigs_to_ids;
+ my @genes_annotation;
+
+ open( my $fh, '-|', $self->_gff_fh_input_string ) or die "Couldnt open GFF file";
+ while(<$fh>)
+ {
+ chomp;
+ my $line = $_;
+ my $id_name;
+ if($line =~/ID=["']?([^;"']+)["']?;?/i)
+ {
+ $id_name= $1;
+ }
+ else
+ {
+ next;
+ }
+
+ my @annotation_elements = split(/\t/,$line);
+ # Map gene IDs to the contig
+ push(@{$contigs_to_ids{$annotation_elements[0]}}, $id_name);
+
+ if($line =~/product=["']?([^;,"']+)[,"']?;?/i)
+ {
+ my %gene_data;
+ $gene_data{product} = $1;
+ $gene_data{id_name} = $id_name;
+ if($line =~ /UniProtKB/ || $line =~ /RefSeq/ || $line =~ /protein motif/)
+ {
+ $gene_data{database_annotation_exists} = 1;
+ }
+ else
+ {
+ $gene_data{database_annotation_exists} = 0;
+ }
+
+ $gene_data{contig} = $annotation_elements[0];
+ $gene_data{start} = $annotation_elements[1];
+ $gene_data{end} = $annotation_elements[2];
+ push(@genes_annotation,\%gene_data);
+ }
+
+ }
+ close($fh);
+
+ $self->_genes_annotation(\@genes_annotation);
+ return \%contigs_to_ids;
+}
+
+sub _build_overlapping_hypothetical_protein_ids
+{
+ my ($self) = @_;
+ $self->contig_to_ids;
+
+ my %overlapping_protein_ids;
+
+ #Checking to see if the current feature is hypotheitical and if the next one has annotation
+ for(my $i = 0; $i< (@{$self->_genes_annotation} -1) ; $i++ )
+ {
+ my $current_feature = $self->_genes_annotation->[$i];
+ my $next_feature = $self->_genes_annotation->[$i+1];
+
+ next if($current_feature->{database_annotation_exists} == 1);
+ next unless($current_feature->{product} =~ /hypothetical/i);
+ next unless($next_feature->{database_annotation_exists} == 1);
+
+ my $start_coord = $current_feature->{start} ;
+ my $end_coord = $current_feature->{end} ;
+ my $comparison_start_coord =$next_feature->{start} ;
+ my $comparison_end_coord =$next_feature->{end} ;
+ if($comparison_start_coord < $end_coord && $comparison_end_coord > $start_coord )
+ {
+ my $percent_overlap = $self->_percent_overlap($start_coord, $end_coord , $comparison_start_coord,$comparison_end_coord);
+ if($percent_overlap >= $self->_min_nucleotide_overlap_percentage)
+ {
+ $overlapping_protein_ids{$current_feature->{id_name}}++;
+ }
+ }
+ }
+
+ return \%overlapping_protein_ids;
+}
+
+sub _percent_overlap
+{
+ my ($self, $start_coord, $end_coord , $comparison_start_coord,$comparison_end_coord) = @_;
+ my $size_of_hypothetical_gene = $end_coord - $start_coord;
+
+ my $lower_bound = $start_coord;
+ if($comparison_start_coord > $start_coord)
+ {
+ $lower_bound = $comparison_start_coord;
+ }
+ my $upper_bound = $end_coord;
+ if($comparison_end_coord < $end_coord )
+ {
+ $upper_bound = $comparison_end_coord;
+ }
+ return (($upper_bound-$lower_bound)*100) / $size_of_hypothetical_gene;
+}
+
+
+sub _build__awk_filter {
+ my ($self) = @_;
+ return
+ 'awk \'BEGIN {FS="\t"};{ if ($3 ~/'
+ . $self->_tags_to_filter
+ . '/) print $1"\t"$4"\t"$5"\t"$9;}\' ';
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/Exceptions.pm b/lib/Bio/Roary/Exceptions.pm
new file mode 100644
index 0000000..0c2e55a
--- /dev/null
+++ b/lib/Bio/Roary/Exceptions.pm
@@ -0,0 +1,16 @@
+package Bio::Roary::Exceptions;
+# ABSTRACT: Exceptions for input data
+
+=head1 SYNOPSIS
+
+Exceptions for input data
+
+=cut
+
+use strict; use warnings;
+use Exception::Class (
+ 'Bio::Roary::Exceptions::FileNotFound' => { description => 'Couldnt open the file' },
+ 'Bio::Roary::Exceptions::CouldntWriteToFile' => { description => 'Couldnt open the file for writing' },
+);
+
+1;
diff --git a/lib/Bio/Roary/External/Blastp.pm b/lib/Bio/Roary/External/Blastp.pm
new file mode 100644
index 0000000..483ab1e
--- /dev/null
+++ b/lib/Bio/Roary/External/Blastp.pm
@@ -0,0 +1,68 @@
+package Bio::Roary::External::Blastp;
+
+# ABSTRACT: Wrapper around NCBIs blastp command
+
+=head1 SYNOPSIS
+
+Wrapper around NCBIs blastp command
+
+ use Bio::Roary::External::Blastp;
+
+ my $blast_database= Bio::Roary::External::Blastp->new(
+ fasta_file => 'contigs.fa',
+ blast_database => 'db',
+ exec => 'blastp',
+ output_file => 'results.out'
+ );
+
+ $blast_database->run();
+
+=method result_file
+
+Returns the path to the results file
+
+=cut
+
+use Moose;
+with 'Bio::Roary::JobRunner::Role';
+
+has 'fasta_file' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'blast_database' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'exec' => ( is => 'ro', isa => 'Str', default => 'blastp' );
+has '_evalue' => ( is => 'ro', isa => 'Num', default => 1E-6 );
+has '_num_threads' => ( is => 'ro', isa => 'Int', default => 1 );
+has '_max_target_seqs' => ( is => 'ro', isa => 'Int', default => 2000 );
+has '_logging' => ( is => 'ro', isa => 'Str', default => '2> /dev/null' );
+has 'output_file' => ( is => 'ro', isa => 'Str', default => 'results.out' );
+has 'perc_identity' => ( is => 'ro', isa => 'Num', default => 98 );
+
+sub _command_to_run {
+ my ($self) = @_;
+ return join(
+ " ",
+ (
+ $self->exec,
+ '-query', $self->fasta_file,
+ '-db', $self->blast_database,
+ '-evalue', $self->_evalue,
+ '-num_threads', $self->_num_threads,
+ '-outfmt 6',
+ '-max_target_seqs', $self->_max_target_seqs,
+ ' | awk \'{ if ($3 > '.$self->perc_identity.') print $0;}\'',
+ $self->_logging, '1> ', $self->output_file,
+ )
+
+
+ );
+}
+
+sub run {
+ my ($self) = @_;
+ $self->logger->info( "Running command: " . $self->_command_to_run() );
+ system( $self->_command_to_run );
+ 1;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+1;
diff --git a/lib/Bio/Roary/External/Cdhit.pm b/lib/Bio/Roary/External/Cdhit.pm
new file mode 100644
index 0000000..716ee07
--- /dev/null
+++ b/lib/Bio/Roary/External/Cdhit.pm
@@ -0,0 +1,103 @@
+package Bio::Roary::External::Cdhit;
+
+# ABSTRACT: Wrapper to run cd-hit
+
+=head1 SYNOPSIS
+
+Wrapper to run cd-hit
+ use Bio::Roary::External::Cdhit;
+
+ my $obj = Bio::Roary::External::Cdhit->new(
+ input_file => 'abc.fa',
+ exec => 'cd-hit',
+ output_base => 'efg',
+ );
+ $obj->run;
+
+=cut
+
+use Moose;
+
+with 'Bio::Roary::JobRunner::Role';
+
+has 'input_file' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'output_base' => ( is => 'ro', isa => 'Str', default => 'output' );
+has 'exec' => ( is => 'ro', isa => 'Str', default => 'cd-hit' );
+has 'alt_exec' => ( is => 'ro', isa => 'Str', default => 'cdhit' );
+has '_max_available_memory_in_mb' => ( is => 'ro', isa => 'Int', lazy => 1, builder => '_build__max_available_memory_in_mb' );
+has '_use_most_similar_clustering' => ( is => 'ro', isa => 'Bool', default => 1 );
+has '_length_difference_cutoff' => ( is => 'ro', isa => 'Num', default => 1 );
+has '_sequence_identity_threshold' => ( is => 'ro', isa => 'Num', default => 1 );
+has '_description_length' => ( is => 'ro', isa => 'Int', default => 256 );
+has '_logging' => ( is => 'ro', isa => 'Str', default => '> /dev/null 2>&1' );
+has '_max_cpus' => ( is => 'ro', isa => 'Int', default => 40 );
+
+
+# Overload Role
+has 'memory_in_mb' => ( is => 'ro', isa => 'Int', lazy => 1, builder => '_build_memory_in_mb' );
+
+sub _build_memory_in_mb
+{
+ my ($self) = @_;
+ my $filename = $self->input_file;
+ my $memory_required = 2000;
+ if(-e $filename)
+ {
+ $memory_required = -s $filename;
+ # Convert to mb
+ $memory_required = int($memory_required/1000000);
+ # Triple memory for worst case senario
+ $memory_required *= 5;
+ $memory_required = 2000 if($memory_required < 2000);
+ }
+
+ return $memory_required;
+}
+
+sub _build__max_available_memory_in_mb
+{
+ my ($self) = @_;
+ my $memory_to_cdhit = int($self->memory_in_mb *0.9);
+ return $memory_to_cdhit;
+}
+
+sub clusters_filename
+{
+ my ($self) = @_;
+ return join('.',($self->output_base,'clstr'));
+}
+
+sub _command_to_run {
+ my ($self) = @_;
+
+ my $executable = $self->_find_exe([$self->exec, $self->alt_exec]);
+
+ my $cpus = ($self->cpus > $self->_max_cpus) ? $self->_max_cpus : $self->cpus;
+ return join(
+ ' ',
+ (
+ $executable, '-i', $self->input_file, '-o',
+ $self->output_base, '-T', $cpus, '-M',
+ $self->_max_available_memory_in_mb, '-g', $self->_use_most_similar_clustering, '-s',
+ $self->_length_difference_cutoff, '-d', $self->_description_length ,'-c', $self->_sequence_identity_threshold,
+ $self->_logging
+ )
+ );
+}
+
+sub run {
+ my ($self) = @_;
+ my @commands_to_run;
+
+ push(@commands_to_run, $self->_command_to_run() );
+ $self->logger->info( "Running command: " . $self->_command_to_run() );
+ my $job_runner_obj = $self->_job_runner_class->new( commands_to_run => \@commands_to_run, memory_in_mb => $self->memory_in_mb, queue => $self->_queue, cpus => $self->cpus );
+ $job_runner_obj->run();
+
+ 1;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/External/CheckTools.pm b/lib/Bio/Roary/External/CheckTools.pm
new file mode 100644
index 0000000..b05593a
--- /dev/null
+++ b/lib/Bio/Roary/External/CheckTools.pm
@@ -0,0 +1,190 @@
+package Bio::Roary::External::CheckTools;
+
+# ABSTRACT: Check external executables are available and are the correct version
+
+=head1 SYNOPSIS
+Functionality borrowed from PROKKA by Torsten Seemann.
+Check external executables are available and are the correct version
+
+ use Bio::Roary::External::CheckTools;
+
+ my $obj = Bio::Roary::External::CheckTools->new();
+ $obj->check_all_tools;
+
+=cut
+
+use Moose;
+use File::Spec;
+use Log::Log4perl qw(:easy);
+has 'logger' => ( is => 'ro', lazy => 1, builder => '_build_logger' );
+
+sub _build_logger {
+ my ($self) = @_;
+ Log::Log4perl->easy_init($DEBUG);
+ my $logger = get_logger();
+ return $logger;
+}
+
+my $BIDEC = '(\d+\.\d+)'; # pattern of NN.NN for versions that can be compared
+
+my %tools = (
+ 'parallel' => {
+ GETVER => "parallel --version | grep '^GNU parallel 2'",
+ REGEXP => qr/GNU parallel (\d+)/,
+ MINVER => "20130422",
+ NEEDED => 1,
+ },
+ 'blastp' => {
+ GETVER => "blastp -version",
+ REGEXP => qr/blastp:\s+(\d+\.\d+\.\d+)/,
+ NEEDED => 1,
+ },
+ 'makeblastdb' => {
+ GETVER => "makeblastdb -version",
+ REGEXP => qr/makeblastdb:\s+(\d+\.\d+\.\d+)/,
+ NEEDED => 1,
+ },
+ 'mcl' => {
+ GETVER => "mcl --version | head -n 1",
+ REGEXP => qr/(\d+\-\d+)/,
+ NEEDED => 1,
+ },
+ 'bedtools' => {
+ GETVER => "bedtools --version",
+ REGEXP => qr/bedtools v($BIDEC)/,
+ MINVER => "2.1",
+ NEEDED => 1,
+ },
+ 'mafft' => {
+ GETVER => "mafft --version < /dev/null 2>&1",
+ REGEXP => qr/v($BIDEC) /,
+ NEEDED => 1,
+ },
+ 'kraken' => {
+ GETVER => "kraken --version | head -n 1",
+ REGEXP => qr/Kraken version kraken-(\d+\.\d+\.\d+.*)/,
+ NEEDED => 0,
+ },
+ 'kraken-report' => {
+ GETVER => "kraken-report --version | head -n 1",
+ REGEXP => qr/Kraken version kraken-(\d+\.\d+\.\d+.*)/,
+ NEEDED => 0,
+ },
+ 'Rscript' => {
+ GETVER => "Rscript --version 2>&1 | head -n 1",
+ REGEXP => qr/R scripting front-end version ($BIDEC)/,
+ MINVER => "3",
+ NEEDED => 0,
+ },
+
+ # prank version also performs an update check so cant use it
+ 'prank' => { NEEDED => 1 },
+
+ # now just the standard unix tools we need
+ 'grep' => { NEEDED => 1 },
+ 'sed' => { NEEDED => 1 },
+ 'awk' => { NEEDED => 1 },
+
+);
+
+my %cdhit_tools = (
+ 'cdhit' => {
+ GETVER => "cdhit -h | grep 'CD-HIT version'",
+ REGEXP => qr/version ($BIDEC) /,
+ MINVER => "4.6",
+ },
+ 'cd-hit' => {
+ GETVER => "cd-hit -h | grep 'CD-HIT version'",
+ REGEXP => qr/version ($BIDEC) /,
+ MINVER => "4.6",
+ }
+);
+
+my %fasttree_tools = (
+ 'fasttree' => {
+ GETVER => "fasttree 2>&1 | head -n 1",
+ REGEXP => qr/Usage for FastTree version ($BIDEC)/,
+ },
+ 'FastTree' => {
+ GETVER => "FastTree 2>&1 | head -n 1",
+ REGEXP => qr/Usage for FastTree version ($BIDEC)/,
+ }
+);
+
+sub which_tool_exec {
+ my ( $self, $alt_tools ) = @_;
+ for my $toolname ( sort keys %{$alt_tools} ) {
+ my $fp = $self->find_exe($toolname);
+ return $toolname if $fp;
+ }
+ $self->logger->error( "Required tool missing. Can't find one of " . join( '/', keys %{$alt_tools} ) . " in your \$PATH." );
+ return undef;
+}
+
+sub check_tool {
+ my ( $self, $toolname ) = @_;
+ my $t = $tools{$toolname};
+ my $fp = $self->find_exe($toolname);
+ $self->logger->error("ERROR: Can't find required '$toolname' in your \$PATH") if !$fp and $t->{NEEDED};
+ $self->logger->error("Optional tool '$toolname' not found in your \$PATH") if !$fp and !$t->{NEEDED};
+
+ if ($fp) {
+ $t->{HAVE} = $fp;
+ $self->logger->warn("Looking for '$toolname' - found $fp");
+ if ( $t->{GETVER} ) {
+ my ($s) = qx($t->{GETVER});
+ if ( defined $s ) {
+ $s =~ $t->{REGEXP};
+ $t->{VERSION} = $1 if defined $1;
+ $self->logger->warn("Determined $toolname version is $t->{VERSION}");
+ if ( defined $t->{MINVER} and $t->{VERSION} < $t->{MINVER} ) {
+ $self->logger->error("Roary needs $toolname $t->{MINVER} or higher. Please upgrade and try again.");
+ }
+ if ( defined $t->{MAXVER} and $t->{VERSION} > $t->{MAXVER} ) {
+ $self->logger->error(
+ "Roary needs a version of $toolname between $t->{MINVER} and $t->{MAXVER}. Please downgrade and try again.");
+ }
+ }
+ else {
+ $self->logger->error( "Could not determine version of $toolname - please install version ", $t->{MINVER}, " or higher" )
+ ; # FIXME: or less <= MAXVER if given
+ }
+ }
+ }
+}
+
+sub check_all_tools {
+ my ($self) = @_;
+ $ENV{"GREP_OPTIONS"} = ''; # --colour => version grep fails (Issue #117)
+ for my $toolname ( sort keys %tools ) {
+ $self->check_tool($toolname);
+ }
+
+ my $cdhit = $self->which_tool_exec( \%cdhit_tools );
+ if ($cdhit) {
+ $tools{$cdhit} = $cdhit_tools{$cdhit};
+ $self->check_tool($cdhit);
+ }
+
+ my $fasttree = $self->which_tool_exec( \%fasttree_tools );
+ if ($fasttree) {
+ $tools{$fasttree} = $fasttree_tools{$fasttree};
+ $self->check_tool($fasttree);
+ }
+
+ return $self;
+}
+
+sub find_exe {
+ my ( $self, $bin ) = @_;
+ for my $dir ( File::Spec->path ) {
+ my $exe = File::Spec->catfile( $dir, $bin );
+ return $exe if -x $exe;
+ }
+ return;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/External/Fasttree.pm b/lib/Bio/Roary/External/Fasttree.pm
new file mode 100644
index 0000000..b29414e
--- /dev/null
+++ b/lib/Bio/Roary/External/Fasttree.pm
@@ -0,0 +1,73 @@
+package Bio::Roary::External::Fasttree;
+
+# ABSTRACT: Wrapper to run Fasttree
+
+=head1 SYNOPSIS
+
+Wrapper to run cd-hit
+ use Bio::Roary::External::Fasttree;
+
+ my $obj = Bio::Roary::External::Fasttree->new(
+ input_file => 'abc.fa',
+ exec => 'Fasttree',
+ output_base => 'efg',
+ );
+ $obj->run;
+
+=cut
+
+use Moose;
+with 'Bio::Roary::JobRunner::Role';
+
+has 'input_file' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'output_file' => ( is => 'ro', isa => 'Str', lazy => 1, builder => '_build_output_file' );
+has 'exec' => ( is => 'ro', isa => 'Str', default => 'FastTree' );
+has 'alt_exec' => ( is => 'ro', isa => 'Str', default => 'fasttree' );
+has '_logging' => ( is => 'ro', isa => 'Str', default => '2> /dev/null' );
+
+sub _build_output_file
+{
+ my ($self) = @_;
+ return $self->input_file.".newick";
+}
+
+sub _command_to_run {
+ my ($self) = @_;
+
+ my $executable = $self->_find_exe([$self->exec, $self->alt_exec]);
+ my $logging_str = "";
+ $logging_str = $self->_logging if(! $self->verbose);
+
+ return join(
+ ' ', ($executable, '-fastest', '-nt', $self->input_file, '>', $self->output_file, $logging_str)
+ );
+}
+
+sub run {
+ my ($self) = @_;
+ my @commands_to_run;
+
+ if(!defined($self->input_file) || ! ( -e $self->input_file))
+ {
+ $self->logger->error( "The input file is missing so not creating a tree" );
+ return 1;
+ }
+
+ if(-s $self->input_file < 5)
+ {
+ $self->logger->info( "The input file is too small so not creating a tree" );
+ return 1;
+ }
+
+ push(@commands_to_run, $self->_command_to_run() );
+ $self->logger->info( "Running command: " . $self->_command_to_run() );
+ my $job_runner_obj = $self->_job_runner_class->new( commands_to_run => \@commands_to_run, memory_in_mb => $self->memory_in_mb, queue => $self->_queue, cpus => $self->cpus );
+ $job_runner_obj->run();
+
+ 1;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/External/GeneAlignmentFromNucleotides.pm b/lib/Bio/Roary/External/GeneAlignmentFromNucleotides.pm
new file mode 100644
index 0000000..cc90548
--- /dev/null
+++ b/lib/Bio/Roary/External/GeneAlignmentFromNucleotides.pm
@@ -0,0 +1,138 @@
+package Bio::Roary::External::GeneAlignmentFromNucleotides;
+
+# ABSTRACT: Take in multi-FASTA files of nucleotides and align each file with PRANK or MAFFT
+
+=head1 SYNOPSIS
+
+Take in multi-FASTA files of nucleotides and align each file with PRANK or MAFFT
+
+ use Bio::Roary::External::GeneAlignmentFromNucleotides;
+
+ my $seg = Bio::Roary::External::GeneAlignmentFromNucleotides->new(
+ fasta_files => [],
+ );
+
+ $seg->run();
+
+=method output_file
+
+Returns the path to the results file
+
+=cut
+
+use Moose;
+with 'Bio::Roary::JobRunner::Role';
+
+has 'fasta_files' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'exec' => ( is => 'ro', isa => 'Str', default => 'protein_alignment_from_nucleotides' );
+has 'translation_table' => ( is => 'rw', isa => 'Int', default => 11 );
+has 'core_definition' => ( is => 'ro', isa => 'Num', default => 1 );
+has 'mafft' => ( is => 'ro', isa => 'Bool', default => 0 );
+has 'dont_delete_files' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'num_input_files' => ( is => 'ro', isa => 'Int', required => 1);
+
+# Overload Role
+has 'memory_in_mb' => ( is => 'rw', isa => 'Int', lazy => 1, builder => '_build_memory_in_mb' );
+has '_min_memory_in_mb' => ( is => 'ro', isa => 'Int', default => 1500 );
+has '_max_memory_in_mb' => ( is => 'ro', isa => 'Int', default => 60000 );
+has '_queue' => ( is => 'rw', isa => 'Str', default => 'normal' );
+has '_files_per_chunk' => ( is => 'ro', isa => 'Int', lazy => 1, builder => '_build__files_per_chunk' );
+has '_core_alignment_cmd' => ( is => 'rw', isa => 'Str', lazy_build => 1 );
+has '_dependancy_memory_in_mb' => ( is => 'ro', isa => 'Int', default => 15000 );
+
+sub _build__files_per_chunk
+{
+ my ($self) = @_;
+ if($self->num_input_files > 1000)
+ {
+ return 5;
+ }
+ elsif($self->num_input_files > 500)
+ {
+ return 7;
+ }
+ return 10;
+}
+
+sub _build_memory_in_mb {
+ my ($self) = @_;
+
+ my $largest_file_size = 1;
+ for my $file (@{$self->fasta_files})
+ {
+ my $file_size = -s $file;
+ if($file_size > $largest_file_size)
+ {
+ $largest_file_size = $file_size;
+ }
+ }
+
+ my $approx_sequence_length_of_largest_file = $largest_file_size/ $self->num_input_files;
+ my $memory_required = int((($approx_sequence_length_of_largest_file*$approx_sequence_length_of_largest_file)/1000000)*2 + $self->_min_memory_in_mb);
+
+ $memory_required = $self->_max_memory_in_mb if($memory_required > $self->_max_memory_in_mb);
+
+ return $memory_required;
+}
+
+sub _command_to_run {
+ my ( $self, $fasta_files) = @_;
+ my $verbose = "";
+ if($self->verbose)
+ {
+ $verbose = ' -v ';
+ }
+ my $mafft_str = "";
+ $mafft_str = ' --mafft ' if($self->mafft);
+ return $self->exec." ".$verbose.$mafft_str.join( " ", @{$fasta_files} );
+}
+
+sub _build__core_alignment_cmd {
+ my ( $self ) = @_;
+
+ my $core_cmd = "pan_genome_core_alignment";
+ $core_cmd .= " -cd " . ($self->core_definition*100) if ( defined $self->core_definition );
+ $core_cmd .= " --dont_delete_files " if ( defined $self->dont_delete_files && $self->dont_delete_files == 1 );
+
+ return $core_cmd;
+}
+
+sub run {
+ my ($self) = @_;
+ my @commands_to_run;
+
+ my @files_chunk;
+ for my $fasta_file ( @{ $self->fasta_files } ) {
+ push(@files_chunk,$fasta_file);
+ if(@files_chunk == $self->_files_per_chunk )
+ {
+ push(@commands_to_run, $self->_command_to_run(\@files_chunk));
+ $self->logger->info( "Running command: " . $self->_command_to_run(\@files_chunk) );
+ @files_chunk = ();
+ }
+ }
+
+ if(@files_chunk > 0)
+ {
+ push(@commands_to_run, $self->_command_to_run(\@files_chunk));
+ $self->logger->info( "Running command: " . $self->_command_to_run(\@files_chunk) );
+ }
+
+ my $job_runner_obj = $self->_job_runner_class->new(
+ commands_to_run => \@commands_to_run,
+ memory_in_mb => $self->memory_in_mb,
+ queue => $self->_queue,
+ dont_wait => 1,
+ cpus => $self->cpus
+ );
+ $job_runner_obj->run();
+
+ $job_runner_obj->memory_in_mb($self->_dependancy_memory_in_mb);
+ $self->logger->info( "Running command: " . $self->_core_alignment_cmd() );
+ $job_runner_obj->submit_dependancy_job($self->_core_alignment_cmd);
+ 1;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+1;
diff --git a/lib/Bio/Roary/External/IterativeCdhit.pm b/lib/Bio/Roary/External/IterativeCdhit.pm
new file mode 100644
index 0000000..91a1db5
--- /dev/null
+++ b/lib/Bio/Roary/External/IterativeCdhit.pm
@@ -0,0 +1,92 @@
+package Bio::Roary::External::IterativeCdhit;
+
+# ABSTRACT: Iteratively run CDhit
+
+=head1 SYNOPSIS
+
+Iteratively run CDhit
+
+ use Bio::Roary::External::IterativeCdhit;
+
+ my $seg= Bio::Roary::External::IterativeCdhit->new(
+ output_cd_hit_filename => '',
+ output_combined_filename => '',
+ number_of_input_files => 10,
+ output_filtered_clustered_fasta => '',
+ );
+
+ $seg->run();
+
+=cut
+
+use Moose;
+with 'Bio::Roary::JobRunner::Role';
+
+has 'output_cd_hit_filename' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'output_combined_filename' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'number_of_input_files' => ( is => 'ro', isa => 'Int', required => 1 );
+has 'output_filtered_clustered_fasta' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'exec' => ( is => 'ro', isa => 'Str', default => 'iterative_cdhit' );
+has '_max_cpus' => ( is => 'ro', isa => 'Int', default => 40 );
+# Overload Role
+has 'memory_in_mb' => ( is => 'ro', isa => 'Int', lazy => 1, builder => '_build_memory_in_mb' );
+
+sub _build_memory_in_mb {
+ my ($self) = @_;
+ my $filename = $self->output_combined_filename;
+ my $memory_required = 2000;
+ if ( -e $filename ) {
+ $memory_required = -s $filename;
+
+ # Convert to mb
+ $memory_required = int( $memory_required / 1000000 );
+
+ # Pentuple memory for worst case senario
+ $memory_required *= 5;
+ $memory_required = 2000 if ( $memory_required < 2000 );
+ }
+
+ return $memory_required;
+}
+
+sub _build__max_available_memory_in_mb {
+ my ($self) = @_;
+ my $memory_to_cdhit = int( $self->memory_in_mb * 0.9 );
+ return $memory_to_cdhit;
+}
+
+sub _command_to_run {
+ my ($self) = @_;
+ my $cpus = ($self->cpus > $self->_max_cpus) ? $self->_max_cpus : $self->cpus;
+
+ return join(
+ ' ',
+ (
+ $self->exec, '-c', $self->output_cd_hit_filename, '-m',
+ $self->output_combined_filename, '-n', $self->number_of_input_files, '--cpus', $cpus, '-f',
+ $self->output_filtered_clustered_fasta
+ )
+ );
+}
+
+sub run {
+ my ($self) = @_;
+ my @commands_to_run;
+ push( @commands_to_run, $self->_command_to_run );
+ $self->logger->info( "Running command: " . $self->_command_to_run() );
+
+ my $job_runner_obj = $self->_job_runner_class->new(
+ commands_to_run => \@commands_to_run,
+ memory_in_mb => $self->memory_in_mb,
+ queue => $self->_queue,
+ cpus => $self->cpus
+ );
+ $job_runner_obj->run();
+
+ 1;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/External/Mafft.pm b/lib/Bio/Roary/External/Mafft.pm
new file mode 100644
index 0000000..d54541c
--- /dev/null
+++ b/lib/Bio/Roary/External/Mafft.pm
@@ -0,0 +1,76 @@
+package Bio::Roary::External::Mafft;
+
+# ABSTRACT: Wrapper to run mafft
+
+=head1 SYNOPSIS
+
+Wrapper to run mafft
+ use Bio::Roary::External::Mafft;
+
+ my $mafft_obj = Bio::Roary::External::Mafft->new(
+ input_filename => $fasta_file,
+ output_filename => $fasta_file.'.aln',
+ job_runner => 'Local'
+ );
+ $mafft_obj->run();
+=cut
+
+use Moose;
+use File::Spec;
+with 'Bio::Roary::JobRunner::Role';
+
+has 'input_filename' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'output_filename' => ( is => 'ro', isa => 'Str', default => 'output' );
+has 'exec' => ( is => 'ro', isa => 'Str', default => 'mafft' );
+
+# Overload Role
+has 'memory_in_mb' => ( is => 'ro', isa => 'Int', lazy => 1, builder => '_build_memory_in_mb' );
+
+sub _build_memory_in_mb {
+ my ($self) = @_;
+ my $memory_required = 2000;
+ return $memory_required;
+}
+
+sub _command_to_run {
+ my ($self) = @_;
+
+ if(! -e $self->input_filename)
+ {
+ $self->logger->error( "Input file to MAFFT missing: " . $self->input_filename );
+ }
+ return join(
+ ' ',
+ (
+ $self->exec,
+ '--auto',
+ '--quiet',
+ $self->input_filename,
+ '>',
+ $self->output_filename
+ )
+ );
+}
+
+sub run {
+ my ($self) = @_;
+ my @commands_to_run;
+
+ push( @commands_to_run, $self->_command_to_run() );
+ $self->logger->info( "Running command: " . $self->_command_to_run() );
+
+ my $job_runner_obj = $self->_job_runner_class->new(
+ commands_to_run => \@commands_to_run,
+ memory_in_mb => $self->memory_in_mb,
+ queue => $self->_queue,
+ cpus => $self->cpus
+ );
+ $job_runner_obj->run();
+
+ 1;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/External/Makeblastdb.pm b/lib/Bio/Roary/External/Makeblastdb.pm
new file mode 100644
index 0000000..e1b75e3
--- /dev/null
+++ b/lib/Bio/Roary/External/Makeblastdb.pm
@@ -0,0 +1,72 @@
+package Bio::Roary::External::Makeblastdb;
+
+# ABSTRACT: Wrapper around NCBIs makeblastdb command
+
+=head1 SYNOPSIS
+
+Take in a fasta file and create a temporary blast database.
+
+ use Bio::Roary::External::Makeblastdb;
+
+ my $blast_database= Bio::Roary::External::Makeblastdb->new(
+ fasta_file => 'contigs.fa',
+ exec => 'makeblastdb'
+ );
+
+ $blast_database->run();
+
+=method output_database
+
+Returns the path to the temporary blast database files
+
+=cut
+
+use Moose;
+use File::Temp;
+use Cwd;
+with 'Bio::Roary::JobRunner::Role';
+
+has 'fasta_file' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'exec' => ( is => 'ro', isa => 'Str', default => 'makeblastdb' );
+has '_working_directory' => ( is => 'ro', isa => 'File::Temp::Dir', default => sub { File::Temp->newdir( DIR => getcwd, CLEANUP => 1 ); } );
+has '_dbtype' => ( is => 'ro', isa => 'Str', default => 'prot' );
+has '_logfile' => ( is => 'ro', isa => 'Str', default => '/dev/null' );
+has 'output_database' => ( is => 'ro', isa => 'Str', lazy => 1, builder => '_build_output_database' );
+
+# Overload Role
+has 'memory_in_mb' => ( is => 'ro', isa => 'Int', default => 4000);
+
+sub _build_output_database {
+ my ($self) = @_;
+ return join( '/', ( $self->_working_directory->dirname(), 'output_contigs' ) );
+}
+
+sub _command_to_run {
+ my ($self) = @_;
+ return join(
+ " ",
+ (
+ $self->exec,
+ '-in', $self->fasta_file,
+ '-dbtype', $self->_dbtype,
+ '-parse_seqids',
+ '-out', $self->output_database,
+ '-logfile', $self->_logfile
+ )
+ );
+}
+
+sub run {
+ my ($self) = @_;
+ my @commands_to_run;
+ push(@commands_to_run, $self->_command_to_run );
+ $self->logger->info( "Running command: " . $self->_command_to_run() );
+ my $job_runner_obj = $self->_job_runner_class->new( commands_to_run => \@commands_to_run, memory_in_mb => $self->memory_in_mb, queue => $self->_queue, cpus => $self->cpus );
+ $job_runner_obj->run();
+
+ 1;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+1;
diff --git a/lib/Bio/Roary/External/Mcl.pm b/lib/Bio/Roary/External/Mcl.pm
new file mode 100644
index 0000000..7ae30d4
--- /dev/null
+++ b/lib/Bio/Roary/External/Mcl.pm
@@ -0,0 +1,106 @@
+package Bio::Roary::External::Mcl;
+
+# ABSTRACT: Wrapper around MCL which takes in blast results and outputs clustered results
+
+=head1 SYNOPSIS
+
+Wrapper around MCL which takes in blast results and outputs clustered results
+
+ use Bio::Roary::External::Mcl;
+
+ my $mcl= Bio::Roary::External::Mcl->new(
+ blast_results => 'db',
+ mcxdeblast_exec => 'mcxdeblast',
+ mcl_exec => 'mcl',
+ output_file => 'output.groups'
+ );
+
+ $mcl->run();
+
+=cut
+
+use Moose;
+use File::Which;
+with 'Bio::Roary::JobRunner::Role';
+
+has 'blast_results' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'mcxdeblast_exec' => ( is => 'ro', isa => 'Str', default => 'mcxdeblast' );
+has '_full_mcxdeblast_exec' => ( is => 'ro', isa => 'Str', lazy => 1, builder => '_build__full_mcxdeblast_exec');
+has 'mcl_exec' => ( is => 'ro', isa => 'Str', default => 'mcl' );
+has 'output_file' => ( is => 'ro', isa => 'Str', default => 'output_groups' );
+
+has '_score' => ( is => 'ro', isa => 'Str', default => 'r' );
+
+has '_inflation_value' => ( is => 'ro', isa => 'Num', default => 1.5 );
+has '_logging' => ( is => 'ro', isa => 'Str', default => '> /dev/null 2>&1' );
+
+has 'memory_in_mb' => ( is => 'ro', isa => 'Int', lazy => 1, builder => '_build_memory_in_mb' );
+
+sub _build_memory_in_mb
+{
+ my ($self) = @_;
+ # Todo: implement this equation for memory estimation if this hardcoded value proves too unstable.
+ # http://micans.org/mcl/man/mcl.html#opt-how-much-ram
+
+ my $filename = $self->blast_results;
+ my $memory_required = 2000;
+ if(-e $filename)
+ {
+ $memory_required = -s $filename;
+ # Convert to mb
+ $memory_required = int($memory_required/1000000);
+ # increase memory for worst case senario
+ $memory_required *= 3;
+ $memory_required += 2000;
+ }
+
+ return $memory_required;
+}
+
+
+sub _build__full_mcxdeblast_exec
+{
+ my ($self) = @_;
+
+ if(-e $self->mcxdeblast_exec)
+ {
+ return $self->mcxdeblast_exec;
+ }
+
+ my $full_exec = which($self->mcxdeblast_exec);
+ if(! defined($full_exec))
+ {
+ $self->logger->error("Cannot find the mcxdeblast executable, please ensure its in your PATH") ;
+ exit();
+ }
+ return "perl $full_exec";
+}
+
+sub _command_to_run {
+ my ($self) = @_;
+ return join(
+ " ",
+ (
+ $self->_full_mcxdeblast_exec, '-m9', '--score='.$self->_score,
+ '--line-mode=abc', $self->blast_results, '2> /dev/null',
+ '|', $self->mcl_exec, '-', '--abc',
+ '-I', $self->_inflation_value, '-o', $self->output_file,
+ $self->_logging
+ )
+ );
+}
+
+sub run {
+ my ($self) = @_;
+ my @commands_to_run;
+ push(@commands_to_run, $self->_command_to_run );
+ $self->logger->info( "Running command: " . $self->_command_to_run() );
+ my $job_runner_obj = $self->_job_runner_class->new( commands_to_run => \@commands_to_run, memory_in_mb => $self->memory_in_mb, queue => $self->_queue, cpus => $self->cpus );
+ $job_runner_obj->run();
+
+ 1;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+1;
diff --git a/lib/Bio/Roary/External/PostAnalysis.pm b/lib/Bio/Roary/External/PostAnalysis.pm
new file mode 100644
index 0000000..211b746
--- /dev/null
+++ b/lib/Bio/Roary/External/PostAnalysis.pm
@@ -0,0 +1,187 @@
+package Bio::Roary::External::PostAnalysis;
+
+# ABSTRACT: Perform the post analysis
+
+=head1 SYNOPSIS
+
+Perform the post analysis
+
+ use Bio::Roary::External::PostAnalysis;
+
+ my $seg= Bio::Roary::External::PostAnalysis->new(
+ fasta_file => 'contigs.fa',
+ );
+
+ $seg->run();
+
+=cut
+
+use Moose;
+use Cwd qw(getcwd);
+with 'Bio::Roary::JobRunner::Role';
+
+has 'input_files' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'exec' => ( is => 'ro', isa => 'Str', default => 'pan_genome_post_analysis' );
+has 'fasta_files' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'output_filename' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'output_pan_geneome_filename' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'output_statistics_filename' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'clusters_filename' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'output_multifasta_files' => ( is => 'ro', isa => 'Bool', required => 1 );
+has 'dont_delete_files' => ( is => 'ro', isa => 'Bool', default => 0 );
+has 'dont_create_rplots' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'dont_split_groups' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'verbose_stats' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'translation_table' => ( is => 'rw', isa => 'Int', default => 11 );
+has 'group_limit' => ( is => 'rw', isa => 'Num', default => 50000 );
+has 'core_definition' => ( is => 'ro', isa => 'Num', default => 1.0 );
+has 'verbose' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'mafft' => ( is => 'ro', isa => 'Bool', default => 0 );
+has '_working_directory' => ( is => 'ro', isa => 'File::Temp::Dir', default => sub { File::Temp->newdir( DIR => getcwd, CLEANUP => 1 ); } );
+has '_gff_fofn' => ( is => 'ro', isa => 'Str', lazy => 1, builder => '_build__gff_fofn' );
+has '_fasta_fofn' => ( is => 'ro', isa => 'Str', lazy => 1, builder => '_build__fasta_fofn' );
+
+# Overload Role
+has 'memory_in_mb' => ( is => 'ro', isa => 'Int', lazy => 1, builder => '_build_memory_in_mb' );
+has '_minimum_memory_mb' => ( is => 'ro', isa => 'Int', default => 4000 );
+has '_memory_per_sample_mb' => ( is => 'ro', isa => 'Int', default => 30 );
+has '_queue' => ( is => 'rw', isa => 'Str', lazy => 1, builder => '_build__queue');
+
+
+sub _build__queue {
+ my ($self) = @_;
+ my $queue = 'normal';
+ my $num_samples = @{ $self->input_files };
+ if($num_samples > 200)
+ {
+ $queue = 'long';
+ }
+ elsif($num_samples > 600)
+ {
+ $queue = 'basement';
+ }
+ return $queue;
+}
+
+
+sub _build_memory_in_mb {
+ my ($self) = @_;
+ my $num_samples = @{ $self->input_files };
+
+ my $memory_required = $num_samples * $self->_memory_per_sample_mb;
+ if ( $memory_required < $self->_minimum_memory_mb ) {
+ $memory_required = $self->_minimum_memory_mb;
+ }
+
+ return $memory_required;
+}
+
+sub _build__gff_fofn
+{
+ my ($self) = @_;
+ return join('/', ($self->_working_directory, '/_gff_files'));
+}
+
+sub _build__fasta_fofn
+{
+ my ($self) = @_;
+ return join('/', ($self->_working_directory, '/_fasta_files'));
+}
+
+
+sub _output_gff_files
+{
+ my ($self) = @_;
+ open(my $out_fh, '>', $self->_gff_fofn);
+ for my $filename (@{$self->input_files})
+ {
+ print {$out_fh} $filename."\n";
+ }
+ close($out_fh);
+}
+
+sub _output_fasta_files
+{
+ my ($self) = @_;
+ open(my $out_fh, '>', $self->_fasta_fofn);
+ for my $filename (@{$self->fasta_files})
+ {
+ print {$out_fh} $filename."\n";
+ }
+ close($out_fh);
+}
+
+sub _command_to_run {
+ my ($self) = @_;
+
+ $self->_output_fasta_files;
+ $self->_output_gff_files;
+
+ my $output_multifasta_files_flag = '';
+ $output_multifasta_files_flag = '--output_multifasta_files' if(defined($self->output_multifasta_files) && $self->output_multifasta_files == 1);
+
+ my $dont_delete_files_flag = '';
+ $dont_delete_files_flag = '--dont_delete_files' if(defined($self->dont_delete_files) && $self->dont_delete_files == 1);
+
+ my $dont_create_rplots_flag = '';
+ $dont_create_rplots_flag = '--dont_create_rplots' if(defined($self->dont_create_rplots) && $self->dont_create_rplots == 1);
+
+ my $dont_split_groups_flag = '';
+ $dont_split_groups_flag = '--dont_split_groups' if ( defined $self->dont_split_groups && $self->dont_split_groups == 1 );
+
+ my $verbose_stats_flag = '';
+ $verbose_stats_flag = '--verbose_stats' if ( defined($self->verbose_stats) && $self->verbose_stats == 1 );
+
+ my $mafft_flag = '';
+ $mafft_flag = '--mafft' if ( defined($self->mafft) && $self->mafft == 1 );
+
+ my $verbose_flag = '';
+ $verbose_flag = '-v' if ( defined($self->verbose) && $self->verbose == 1 );
+
+ return join(
+ " ",
+ (
+ $self->exec,
+ '-o', $self->output_filename,
+ '-p', $self->output_pan_geneome_filename,
+ '-s', $self->output_statistics_filename,
+ '-c', $self->clusters_filename,
+ $output_multifasta_files_flag,
+ '-i', $self->_gff_fofn,
+ '-f', $self->_fasta_fofn,
+ '-t', $self->translation_table,
+ $dont_delete_files_flag,
+ $dont_create_rplots_flag,
+ $dont_split_groups_flag,
+ $verbose_stats_flag,
+ $verbose_flag,
+ $mafft_flag,
+ '-j', $self->job_runner,
+ '--processors', $self->cpus,
+ '--group_limit', $self->group_limit,
+ '-cd', ($self->core_definition*100)
+ )
+ );
+}
+
+sub run {
+ my ($self) = @_;
+
+ my @commands_to_run;
+ push( @commands_to_run, $self->_command_to_run );
+ $self->logger->info( "Running command: " . $self->_command_to_run() );
+ my $job_runner_obj = $self->_job_runner_class->new(
+ commands_to_run => \@commands_to_run,
+ memory_in_mb => $self->memory_in_mb,
+ queue => $self->_queue,
+ dont_wait => $self->dont_wait,
+ cpus => $self->cpus
+ );
+ $job_runner_obj->run();
+
+ 1;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+1;
diff --git a/lib/Bio/Roary/External/Prank.pm b/lib/Bio/Roary/External/Prank.pm
new file mode 100644
index 0000000..be40ac3
--- /dev/null
+++ b/lib/Bio/Roary/External/Prank.pm
@@ -0,0 +1,77 @@
+package Bio::Roary::External::Prank;
+
+# ABSTRACT: Wrapper to run prank
+
+=head1 SYNOPSIS
+
+Wrapper to run cd-hit
+ use Bio::Roary::External::Prank;
+
+ my $prank_obj = Bio::Roary::External::Prank->new(
+ input_filename => $fasta_file,
+ output_filename => $fasta_file.'.aln',
+ job_runner => 'Local'
+ );
+ $prank_obj->run();
+=cut
+
+use Moose;
+use File::Spec;
+with 'Bio::Roary::JobRunner::Role';
+
+has 'input_filename' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'output_filename' => ( is => 'ro', isa => 'Str', default => 'output' );
+has 'exec' => ( is => 'ro', isa => 'Str', default => 'prank' );
+
+# Overload Role
+has 'memory_in_mb' => ( is => 'ro', isa => 'Int', lazy => 1, builder => '_build_memory_in_mb' );
+
+sub _build_memory_in_mb {
+ my ($self) = @_;
+ my $memory_required = 2000;
+ return $memory_required;
+}
+
+sub _command_to_run {
+ my ($self) = @_;
+
+ if(! -e $self->input_filename)
+ {
+ $self->logger->error( "Input file to PRANK missing: " . $self->input_filename );
+ }
+
+ return join(
+ ' ',
+ (
+ $self->exec,
+ "-d=" . $self->input_filename,
+ "-o=" . $self->output_filename,
+ '-codon', '-F', '-quiet', '-once', '> /dev/null 2>&1',
+ '&&', 'mv', $self->output_filename . '*.fas',
+ $self->output_filename
+ )
+ );
+}
+
+sub run {
+ my ($self) = @_;
+ my @commands_to_run;
+
+ push( @commands_to_run, $self->_command_to_run() );
+ $self->logger->info( "Running command: " . $self->_command_to_run() );
+
+ my $job_runner_obj = $self->_job_runner_class->new(
+ commands_to_run => \@commands_to_run,
+ memory_in_mb => $self->memory_in_mb,
+ queue => $self->_queue,
+ cpus => $self->cpus
+ );
+ $job_runner_obj->run();
+
+ 1;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/ExtractCoreGenesFromSpreadsheet.pm b/lib/Bio/Roary/ExtractCoreGenesFromSpreadsheet.pm
new file mode 100644
index 0000000..9fa6fed
--- /dev/null
+++ b/lib/Bio/Roary/ExtractCoreGenesFromSpreadsheet.pm
@@ -0,0 +1,170 @@
+package Bio::Roary::ExtractCoreGenesFromSpreadsheet;
+
+# ABSTRACT: Take in a spreadsheet produced by the pipeline and identify the core genes.
+
+=head1 SYNOPSIS
+
+Take in a spreadsheet produced by the pipeline and identify the core genes.
+ use Bio::Roary::ExtractCoreGenesFromSpreadsheet;
+
+ my $obj = Bio::Roary::ExtractCoreGenesFromSpreadsheet->new(
+ spreadsheet => 'group_statistics.csv',
+ );
+ $obj->ordered_core_genes();
+
+=cut
+
+use Moose;
+use Text::CSV;
+use Bio::Roary::GroupStatistics;
+use POSIX;
+
+has 'spreadsheet' => ( is => 'ro', isa => 'Str', required => 1 );
+has '_csv_parser' => ( is => 'ro', isa => 'Text::CSV',lazy => 1, builder => '_build__csv_parser' );
+has '_input_spreadsheet_fh' => ( is => 'ro', lazy => 1, builder => '_build__input_spreadsheet_fh' );
+has 'ordered_core_genes' => ( is => 'ro', isa => 'ArrayRef', lazy => 1, builder => '_build_ordered_core_genes' );
+has 'core_definition' => ( is => 'ro', isa => 'Num', default => 1 );
+has 'sample_names' => ( is => 'rw', isa => 'ArrayRef', default => sub {[]} );
+has 'sample_names_to_genes' => ( is => 'rw', isa => 'HashRef', default => sub {{}} );
+
+has '_number_of_isolates' => ( is => 'rw', isa => 'Int');
+has '_gene_column' => ( is => 'rw', isa => 'Int');
+has '_num_isolates_column' => ( is => 'rw', isa => 'Int');
+has '_avg_sequences_per_isolate_column' => ( is => 'rw', isa => 'Int');
+has '_genome_fragement_column' => ( is => 'rw', isa => 'Int');
+has '_order_within_fragement_column' => ( is => 'rw', isa => 'Int');
+has '_min_no_isolates_for_core' => ( is => 'rw', isa => 'Num', lazy => 1, builder => '_build__min_no_isolates_for_core' );
+
+sub _build__min_no_isolates_for_core {
+ my ($self) = @_;
+ my $threshold = $self->_number_of_isolates * $self->core_definition;
+
+ return $threshold;
+}
+
+sub _build__csv_parser
+{
+ my ($self) = @_;
+ return Text::CSV->new( { binary => 1, always_quote => 1} );
+}
+
+sub _build__input_spreadsheet_fh {
+ my ($self) = @_;
+ open( my $fh, $self->spreadsheet );
+ return $fh;
+}
+
+sub _update_number_of_isolates
+{
+ my ($self, $header_row) = @_;
+ my $number_of_isolates = @{$header_row} - @{Bio::Roary::GroupStatistics->fixed_headers};
+ $self->_number_of_isolates($number_of_isolates);
+}
+
+sub _setup_column_mappings
+{
+ my ($self, $header_row) = @_;
+ # current ordering
+ my %columns_of_interest_mappings = (
+ 'Gene' => 0,
+ 'No. isolates' => 3,
+ 'Avg sequences per isolate' => 5,
+ 'Genome Fragment' => 6,
+ 'Order within Fragment' => 7,
+ 'QC' => 10,
+ );
+
+ # Dynamically overwrite the default ordering
+ for(my $i = 0; $i < @{$header_row}; $i++)
+ {
+ for my $col_name (%columns_of_interest_mappings)
+ {
+ if($header_row->[$i] eq $col_name)
+ {
+ $columns_of_interest_mappings{$col_name} = $i;
+ last;
+ }
+ }
+ }
+ $self->_gene_column($columns_of_interest_mappings{'Gene'});
+ $self->_num_isolates_column($columns_of_interest_mappings{'No. isolates'});
+ $self->_avg_sequences_per_isolate_column($columns_of_interest_mappings{'Avg sequences per isolate'});
+ $self->_genome_fragement_column($columns_of_interest_mappings{'Genome Fragment'});
+ $self->_order_within_fragement_column($columns_of_interest_mappings{'Order within Fragment'});
+ $self->_update_number_of_isolates($header_row);
+
+ # Get the sample_names
+ my @sample_names;
+ for(my $i = $self->_length_of_fixed_headers(); $i < @{$header_row}; $i++)
+ {
+ push(@sample_names,$header_row->[$i]);
+ }
+ $self->sample_names(\@sample_names);
+}
+
+sub _length_of_fixed_headers
+{
+ my ($self) = @_;
+ return @{Bio::Roary::GroupStatistics->fixed_headers()};
+}
+
+sub _populate_sample_to_gene_lookup_with_row
+{
+ my ($self, $row) = @_;
+
+ for(my $i = $self->_length_of_fixed_headers(); $i < @{$row}; $i++ )
+ {
+ if(defined($row->[$i]) && $row->[$i] ne "" )
+ {
+ my $sample_name = $self->sample_names->[$i - $self->_length_of_fixed_headers()];
+
+ $self->sample_names_to_genes->{$sample_name}->{$row->[$i]} = 1;
+ }
+ }
+ return 1;
+}
+
+
+sub _ordered_core_genes
+{
+ my ($self) = @_;
+ my %ordered_genes;
+ while ( my $row = $self->_csv_parser->getline( $self->_input_spreadsheet_fh ) )
+ {
+ next if(@{$row} < 12); # no genes in group
+ next if(!defined($row->[$self->_gene_column]) || $row->[$self->_gene_column] eq '' ); # no gene name
+ next if(!defined($row->[$self->_avg_sequences_per_isolate_column]) || $row->[$self->_avg_sequences_per_isolate_column] eq '' ); # no average
+ next if(!defined($row->[$self->_genome_fragement_column]) || $row->[$self->_genome_fragement_column] eq '' ); # fragment not defined
+
+ # next if($self->_number_of_isolates != $row->[$self->_num_isolates_column]); # if gene is not in all isolates
+ next if ( $row->[$self->_num_isolates_column] < $self->_min_no_isolates_for_core );
+ next if($row->[$self->_avg_sequences_per_isolate_column] != 1);
+ $ordered_genes{$row->[$self->_genome_fragement_column]}{$row->[$self->_order_within_fragement_column]} = $row->[$self->_gene_column];
+ $self->_populate_sample_to_gene_lookup_with_row($row);
+ }
+
+ my @ordered_core_genes ;
+ for my $fragment_key(sort {$a <=> $b } keys %ordered_genes)
+ {
+ for my $order_within_fragement(sort {$a <=> $b } keys %{$ordered_genes{$fragment_key}})
+ {
+ push(@ordered_core_genes,$ordered_genes{$fragment_key}{$order_within_fragement});
+ }
+ }
+ return \@ordered_core_genes;
+}
+
+sub _build_ordered_core_genes
+{
+ my ($self) = @_;
+ my $header_row = $self->_csv_parser->getline( $self->_input_spreadsheet_fh );
+ $self->_setup_column_mappings($header_row);
+
+ return $self->_ordered_core_genes();
+}
+
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/ExtractProteomeFromGFF.pm b/lib/Bio/Roary/ExtractProteomeFromGFF.pm
new file mode 100644
index 0000000..3f83345
--- /dev/null
+++ b/lib/Bio/Roary/ExtractProteomeFromGFF.pm
@@ -0,0 +1,197 @@
+package Bio::Roary::ExtractProteomeFromGFF;
+
+# ABSTRACT: Take in a GFF file and create protein sequences in FASTA format
+
+=head1 SYNOPSIS
+
+Take in GFF files and create protein sequences in FASTA format
+ use Bio::Roary::ExtractProteomeFromGFF;
+
+ my $obj = Bio::Roary::ExtractProteomeFromGFF->new(
+ gff_file => $fasta_file,
+ );
+ $obj->fasta_file();
+
+=cut
+
+use Moose;
+use Bio::SeqIO;
+use Cwd;
+use Bio::Roary::Exceptions;
+use File::Basename;
+use File::Temp;
+use File::Copy;
+use Bio::Tools::GFF;
+with 'Bio::Roary::JobRunner::Role';
+with 'Bio::Roary::BedFromGFFRole';
+
+has 'gff_file' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'apply_unknowns_filter' => ( is => 'rw', isa => 'Bool', default => 1 );
+has 'maximum_percentage_of_unknowns' => ( is => 'ro', isa => 'Num', default => 5 );
+has 'output_filename' => ( is => 'ro', isa => 'Str', lazy => 1, builder => '_build_output_filename' );
+has 'fasta_file' => ( is => 'ro', isa => 'Str', lazy => 1, builder => '_build_fasta_file' );
+has '_working_directory' => ( is => 'ro', isa => 'File::Temp::Dir', default => sub { File::Temp->newdir( DIR => getcwd, CLEANUP => 1 ); } );
+has '_working_directory_name' => ( is => 'ro', isa => 'Str', lazy => 1, builder => '_build__working_directory_name' );
+has 'translation_table' => ( is => 'rw', isa => 'Int', default => 11 );
+
+sub _build_fasta_file {
+ my ($self) = @_;
+ $self->_extract_nucleotide_regions;
+ $self->_convert_nucleotide_to_protein;
+ $self->_cleanup_fasta;
+ $self->_cleanup_intermediate_files;
+ $self->_filter_fasta_sequences( join('/',($self->output_directory,$self->output_filename)) );
+ return join('/',($self->output_directory,$self->output_filename));
+}
+
+sub _build__working_directory_name {
+ my ($self) = @_;
+ return $self->_working_directory->dirname();
+}
+
+sub _build_output_filename {
+ my ($self) = @_;
+ my ( $filename, $directories, $suffix ) = fileparse( $self->gff_file, qr/\.[^.]*/ );
+ return join( '/', ( $self->_working_directory_name, $filename . '.faa' ) );
+}
+
+
+
+sub _cleanup_intermediate_files {
+ my ($self) = @_;
+ unlink( $self->_unfiltered_output_filename );
+ unlink( $self->_fastatranslate_filename );
+}
+
+sub _nucleotide_fasta_file_from_gff_filename {
+ my ($self) = @_;
+ return join('/',($self->output_directory,join( '.', ( $self->output_filename, 'intermediate.fa' ) )));
+}
+
+sub _extracted_nucleotide_fasta_file_from_bed_filename {
+ my ($self) = @_;
+ return join('/',($self->output_directory,join( '.', ( $self->output_filename,'intermediate.extracted.fa' ) )));
+}
+
+sub _unfiltered_output_filename {
+ my $self = shift;
+ return join('/',($self->output_directory,join( '.', ( $self->output_filename, 'unfiltered.fa' ) )));
+}
+
+
+sub _create_nucleotide_fasta_file_from_gff {
+ my ($self) = @_;
+ my $cmd = 'sed -n \'/##FASTA/,//p\' ' . $self->gff_file . ' | grep -v \'##FASTA\' > ' . $self->_nucleotide_fasta_file_from_gff_filename;
+ $self->logger->debug($cmd);
+ system($cmd);
+}
+
+sub _extract_nucleotide_regions {
+ my ($self) = @_;
+
+ $self->_create_nucleotide_fasta_file_from_gff;
+ $self->_create_bed_file_from_gff;
+
+ my $cmd =
+ 'bedtools getfasta -s -fi '
+ . $self->_nucleotide_fasta_file_from_gff_filename
+ . ' -bed '
+ . $self->_bed_output_filename . ' -fo '
+ . $self->_extracted_nucleotide_fasta_file_from_bed_filename
+ . ' -name > /dev/null 2>&1';
+
+ $self->logger->debug($cmd);
+ system($cmd);
+ unlink( $self->_nucleotide_fasta_file_from_gff_filename );
+ unlink( $self->_bed_output_filename );
+ unlink( $self->_nucleotide_fasta_file_from_gff_filename . '.fai' );
+}
+
+sub _cleanup_fasta {
+ my $self = shift;
+ my $infile = $self->_unfiltered_output_filename;
+ my $outfile = join('/',($self->output_directory,$self->output_filename));
+ return unless ( -e $infile );
+
+ open( my $in, '<', $infile );
+ open( my $out, '>', $outfile );
+ while ( my $line = <$in> ) {
+ chomp $line;
+ $line =~ s/"//g if ( $line =~ /^>/ );
+ print $out "$line\n";
+ }
+ close $in;
+ close $out;
+}
+
+sub _fastatranslate_filename {
+ my ($self) = @_;
+ return join('/',($self->output_directory,join( '.', ( $self->output_filename, 'intermediate.translate.fa' ) )));
+}
+
+sub _fastatranslate {
+ my ( $self, $inputfile, $outputfile ) = @_;
+
+ my $input_fasta_file_obj = Bio::SeqIO->new( -file => $inputfile, -format => 'Fasta' );
+ my $output_protein_file_obj = Bio::SeqIO->new( -file => ">" . $outputfile, -format => 'Fasta', -alphabet => 'protein' );
+
+ my %protein_sequence_objs;
+ while ( my $seq = $input_fasta_file_obj->next_seq ) {
+ $seq->desc(undef);
+ my $protseq = $seq->translate( -codontable_id => $self->translation_table );
+ $output_protein_file_obj->write_seq($protseq);
+ }
+ return 1;
+}
+
+sub _convert_nucleotide_to_protein {
+ my ($self) = @_;
+ $self->_fastatranslate( $self->_extracted_nucleotide_fasta_file_from_bed_filename, $self->_unfiltered_output_filename );
+ unlink( $self->_extracted_nucleotide_fasta_file_from_bed_filename );
+}
+
+sub _does_sequence_contain_too_many_unknowns {
+ my ( $self, $sequence_obj ) = @_;
+ my $maximum_number_of_Xs = int( ( $sequence_obj->length() * $self->maximum_percentage_of_unknowns ) / 100 );
+ my $number_of_Xs_found = () = $sequence_obj->seq() =~ /X/g;
+ if ( $number_of_Xs_found > $maximum_number_of_Xs ) {
+ return 1;
+ }
+ else {
+ return 0;
+ }
+}
+
+sub _filter_fasta_sequences {
+ my ( $self, $filename ) = @_;
+ my $temp_output_file = $filename . '.tmp.filtered.fa';
+ my $out_fasta_obj = Bio::SeqIO->new( -file => ">" . $temp_output_file, -format => 'Fasta' );
+ my $fasta_obj = Bio::SeqIO->new( -file => $filename, -format => 'Fasta' );
+
+ my $sequence_found = 0;
+
+ while ( my $seq = $fasta_obj->next_seq() ) {
+ if ( $self->_does_sequence_contain_too_many_unknowns($seq) ) {
+ next;
+ }
+ $seq->desc(undef);
+ $out_fasta_obj->write_seq($seq);
+ $sequence_found = 1;
+ }
+
+ if ( $sequence_found == 0 ) {
+ $self->logger->error( "Could not extract any protein sequences from "
+ . $self->gff_file
+ . ". Does the file contain the assembly as well as the annotation?" );
+ }
+
+ # Replace the original file.
+ move( $temp_output_file, $filename );
+ return 1;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
+
diff --git a/lib/Bio/Roary/ExtractProteomeFromGFFs.pm b/lib/Bio/Roary/ExtractProteomeFromGFFs.pm
new file mode 100644
index 0000000..241d3b8
--- /dev/null
+++ b/lib/Bio/Roary/ExtractProteomeFromGFFs.pm
@@ -0,0 +1,80 @@
+package Bio::Roary::ExtractProteomeFromGFFs;
+
+# ABSTRACT: Take in GFF files and create protein sequences in FASTA format
+
+=head1 SYNOPSIS
+
+Take in GFF files and create protein sequences in FASTA format
+ use Bio::Roary::ExtractProteomeFromGFFs;
+
+ my $plot_groups_obj = Bio::Roary::ExtractProteomeFromGFFs->new(
+ gff_files => $fasta_files,
+ );
+ $plot_groups_obj->fasta_files();
+
+=cut
+
+use Moose;
+use Bio::Roary::Exceptions;
+use Bio::Roary::ExtractProteomeFromGFF;
+use File::Basename;
+use Cwd qw(getcwd);
+use File::Temp;
+with 'Bio::Roary::JobRunner::Role';
+
+has 'gff_files' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'fasta_files' => ( is => 'ro', isa => 'ArrayRef', lazy => 1, builder => '_build_fasta_files' );
+has 'fasta_files_to_gff_files' => ( is => 'ro', isa => 'HashRef', lazy => 1, builder => '_build_fasta_files_to_gff_files' );
+has 'apply_unknowns_filter' => ( is => 'rw', isa => 'Bool', default => 1 );
+has '_queue' => ( is => 'rw', isa => 'Str', default => 'small' );
+has 'translation_table' => ( is => 'rw', isa => 'Int', default => 11 );
+has 'verbose' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'working_directory' => ( is => 'ro', isa => 'File::Temp::Dir', default => sub { File::Temp->newdir( DIR => getcwd, CLEANUP => 1 ); } );
+
+sub _build__extract_proteome_objects
+{
+ my ($self) = @_;
+
+ my %extract_proteome_objects;
+ for my $filename ( @{ $self->gff_files } ) {
+ my $extract_proteome = Bio::Roary::ExtractProteomeFromGFF->new(
+ gff_file => $filename,
+ );
+ $extract_proteome_objects{ $filename } = $extract_proteome;
+ }
+ return \%extract_proteome_objects;
+}
+
+sub _build_fasta_files {
+ my ($self) = @_;
+ my @fasta_files = sort values( %{$self->fasta_files_to_gff_files} );
+ return \@fasta_files;
+}
+
+sub _build_fasta_files_to_gff_files {
+ my ($self) = @_;
+
+ my %fasta_files;
+ my @commands_to_run;
+ for my $filename ( @{ $self->gff_files } )
+ {
+ print "Extracting proteins from $filename\n" if($self->verbose);
+ my($gff_filename_without_directory, $directories, $suffix) = fileparse($filename);
+ my $output_suffix = "proteome.faa";
+
+ my $output_filename = $filename.'.'.$output_suffix;
+ $fasta_files{ $filename } = $self->working_directory.'/'.$gff_filename_without_directory.'.'.$output_suffix;
+ push(@commands_to_run, "extract_proteome_from_gff --translation_table ".$self->translation_table." --apply_unknowns_filter ".$self->apply_unknowns_filter." -d ".$self->working_directory." -o $output_suffix $filename");
+ }
+ #Farm out the computation and block until its ready
+ my $job_runner_obj = $self->_job_runner_class->new( commands_to_run => \@commands_to_run, memory_in_mb => $self->memory_in_mb, queue => $self->_queue, cpus => $self->cpus);
+ $job_runner_obj->run();
+
+ return \%fasta_files;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
+
diff --git a/lib/Bio/Roary/FilterFullClusters.pm b/lib/Bio/Roary/FilterFullClusters.pm
new file mode 100644
index 0000000..5109a7a
--- /dev/null
+++ b/lib/Bio/Roary/FilterFullClusters.pm
@@ -0,0 +1,144 @@
+package Bio::Roary::FilterFullClusters;
+
+# ABSTRACT: Take an a clusters file from CD-hit and the fasta file and output a fasta file without full clusters
+
+=head1 SYNOPSIS
+
+Take an a clusters file from CD-hit and the fasta file and output a fasta file without full clusters
+ use Bio::Roary::FilterFullClusters;
+
+ my $obj = Bio::Roary::FilterFullClusters->new(
+ clusters_filename => $cluster_file,
+ fasta_file => $fasta_file,
+ number_of_input_files => 10,
+ output_file => 'filtered_file'
+ );
+ $obj->filter_full_clusters_from_fasta();
+
+=cut
+
+use Moose;
+use Bio::SeqIO;
+with 'Bio::Roary::ClustersRole';
+
+has 'number_of_input_files' => ( is => 'ro', isa => 'Int', required => 1 );
+has 'fasta_file' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'output_file' => ( is => 'ro', isa => 'Str', required => 1 );
+has '_greater_than_or_equal' => ( is => 'ro', isa => 'Bool', default => 0 );
+has 'cdhit_input_fasta_file' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'cdhit_output_fasta_file' => ( is => 'ro', isa => 'Str', required => 1 );
+
+has 'output_groups_file' => ( is => 'ro', isa => 'Str', required => 1 );
+
+has '_full_cluster_gene_names' => ( is => 'ro', isa => 'HashRef', lazy => 1, builder => '_build__full_cluster_gene_names' );
+has '_input_seqio' => ( is => 'ro', isa => 'Bio::SeqIO', lazy => 1, builder => '_build__input_seqio' );
+has '_output_seqio' => ( is => 'ro', isa => 'Bio::SeqIO', lazy => 1, builder => '_build__output_seqio' );
+
+has '_all_full_cluster_genes' => ( is => 'ro', isa => 'HashRef', lazy => 1, builder => '_build__all_full_cluster_genes' );
+
+sub _build__full_cluster_gene_names
+{
+ my($self) = @_;
+
+ my %full_cluster_gene_names ;
+
+ for my $gene_name (keys %{$self->_clustered_genes})
+ {
+
+ if($self->_greater_than_or_equal == 0)
+ {
+ if(defined($self->_clustered_genes->{$gene_name}) && @{$self->_clustered_genes->{$gene_name}} >= ($self->number_of_input_files -1))
+ {
+ $full_cluster_gene_names{$gene_name}++;
+ }
+ }
+ else
+ {
+ if(defined($self->_clustered_genes->{$gene_name}) && @{$self->_clustered_genes->{$gene_name}} == ($self->number_of_input_files -1))
+ {
+ $full_cluster_gene_names{$gene_name}++;
+ }
+ }
+ }
+
+ return \%full_cluster_gene_names;
+}
+
+sub _build__input_seqio {
+ my ($self) = @_;
+ return Bio::SeqIO->new( -file => $self->fasta_file, -format => 'Fasta' );
+}
+
+sub _build__output_seqio {
+ my ( $self, $chunk_number ) = @_;
+ return Bio::SeqIO->new( -file => ">".$self->output_file, -format => 'Fasta' );
+}
+
+sub _build__all_full_cluster_genes
+{
+ my ($self) = @_;
+ my %full_cluster_genes;
+
+ for my $gene_name (keys %{$self->_full_cluster_gene_names})
+ {
+ $full_cluster_genes{$gene_name}++;
+ for my $cluster_gene_name (@{$self->_clustered_genes->{$gene_name}})
+ {
+ $full_cluster_genes{$cluster_gene_name}++;
+ }
+ }
+ return \%full_cluster_genes;
+}
+
+
+sub _create_groups_file
+{
+ my ($self) = @_;
+ open(my $out_fh, '>>', $self->output_groups_file);
+
+ for my $gene_name (keys %{$self->_full_cluster_gene_names})
+ {
+ print {$out_fh} $gene_name."\t". join("\t", @{$self->_clustered_genes->{$gene_name}}). "\n";
+ }
+ close($out_fh);
+}
+
+
+
+sub filter_complete_cluster_from_original_fasta
+{
+ my ($self) = @_;
+
+ my $input_seq_io = Bio::SeqIO->new( -file => $self->cdhit_input_fasta_file, -format => 'Fasta' );
+ my $output_seq_io = Bio::SeqIO->new( -file => ">".$self->cdhit_output_fasta_file, -format => 'Fasta' );
+
+ while ( my $input_seq = $input_seq_io->next_seq() )
+ {
+ unless(defined($self->_all_full_cluster_genes->{$input_seq->display_id}))
+ {
+ $output_seq_io->write_seq($input_seq);
+ }
+ }
+
+ $self->_create_groups_file;
+ return $self;
+}
+
+sub filter_full_clusters_from_fasta
+{
+ my ($self) = @_;
+
+ while ( my $input_seq = $self->_input_seqio->next_seq() ) {
+ unless(defined($self->_full_cluster_gene_names->{$input_seq->display_id}))
+ {
+ $self->_output_seqio->write_seq($input_seq);
+ }
+ }
+ return $self;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
+
diff --git a/lib/Bio/Roary/FilterUnknownsFromFasta.pm b/lib/Bio/Roary/FilterUnknownsFromFasta.pm
new file mode 100644
index 0000000..ce48f35
--- /dev/null
+++ b/lib/Bio/Roary/FilterUnknownsFromFasta.pm
@@ -0,0 +1,88 @@
+package Bio::Roary::FilterUnknownsFromFasta;
+
+# ABSTRACT: Take in fasta files, remove sequences with too many unknowns and return a list of the new files
+
+=head1 SYNOPSIS
+
+Take in fasta files, remove sequences with too many unknowns and return a list of the new files
+ use Bio::Roary::FilterUnknownsFromFasta;
+
+ my $obj = Bio::Roary::FilterUnknownsFromFasta->new(
+ fasta_files => [],
+ );
+ $obj->filtered_fasta_files();
+
+=cut
+
+use Moose;
+use Bio::SeqIO;
+use Cwd;
+use Bio::Roary::Exceptions;
+use File::Basename;
+
+has 'fasta_files' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'apply_unknowns_filter' => ( is => 'rw', isa => 'Bool', default => 1 );
+has 'maximum_percentage_of_unknowns' => ( is => 'ro', isa => 'Num', default => 5 );
+
+has 'filtered_fasta_files' => ( is => 'ro', isa => 'ArrayRef', lazy => 1, builder => '_build_filtered_fasta_files' );
+
+has 'input_fasta_to_output_fasta' => ( is => 'ro', isa => 'HashRef', default => sub {{}} );
+
+sub _build_filtered_fasta_files
+{
+ my ($self) = @_;
+
+ my @output_file_names;
+ for my $fasta_file (@{$self->fasta_files})
+ {
+ my ( $filename, $directories, $suffix ) = fileparse($fasta_file);
+ push(@output_file_names, $self->_filter_fasta_sequences_and_return_new_file($filename,$fasta_file ));
+ }
+ return \@output_file_names;
+}
+
+sub _does_sequence_contain_too_many_unknowns
+{
+ my ($self, $sequence_obj) = @_;
+ my $maximum_number_of_Xs = int(($sequence_obj->length()*$self->maximum_percentage_of_unknowns)/100);
+ my $number_of_Xs_found = () = $sequence_obj->seq() =~ /X/g;
+ if($number_of_Xs_found > $maximum_number_of_Xs)
+ {
+ return 1;
+ }
+ else
+ {
+ return 0;
+ }
+}
+
+
+sub _filter_fasta_sequences_and_return_new_file
+{
+ my ($self, $output_file, $input_file) = @_;
+ my $output_filename = $output_file.'.tmp.filtered.fa';
+ my $out_fasta_obj = Bio::SeqIO->new( -file => ">".$output_filename, -format => 'Fasta');
+ my $fasta_obj = Bio::SeqIO->new( -file => $input_file, -format => 'Fasta');
+
+ $self->input_fasta_to_output_fasta->{$input_file} = $output_filename;
+
+ while(my $seq = $fasta_obj->next_seq())
+ {
+ if($self->_does_sequence_contain_too_many_unknowns($seq))
+ {
+ next;
+ }
+ # strip out extra details put in by fastatranslate
+ $seq->description(undef);
+ $out_fasta_obj->write_seq($seq);
+ }
+ return $output_filename;
+}
+
+
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
+
diff --git a/lib/Bio/Roary/GeneNamesFromGFF.pm b/lib/Bio/Roary/GeneNamesFromGFF.pm
new file mode 100644
index 0000000..804d7ed
--- /dev/null
+++ b/lib/Bio/Roary/GeneNamesFromGFF.pm
@@ -0,0 +1,73 @@
+package Bio::Roary::GeneNamesFromGFF;
+
+# ABSTRACT: Parse a GFF and efficiently extract ID -> Gene Name
+
+=head1 SYNOPSIS
+
+Parse a GFF and efficiently extract ID -> Gene Name
+ use Bio::Roary::GeneNamesFromGFF;
+
+ my $obj = Bio::Roary::GeneNamesFromGFF->new(
+ gff_file => 'abc.gff'
+ );
+ $obj->ids_to_gene_name;
+
+=cut
+
+use Moose;
+
+use Bio::Tools::GFF;
+with 'Bio::Roary::ParseGFFAnnotationRole';
+
+has 'ids_to_gene_name' => ( is => 'ro', isa => 'HashRef', lazy => 1, builder => '_build_ids_to_gene_name' );
+has 'ids_to_product' => ( is => 'rw', isa => 'HashRef', default => sub { {} } );
+has 'ids_to_gene_size' => ( is => 'rw', isa => 'HashRef', default => sub { {} } );
+
+# Parsing with the perl GFF module is exceptionally slow.
+sub _build_ids_to_gene_name {
+ my ($self) = @_;
+ my %id_to_gene_name;
+
+ my $gffio = Bio::Tools::GFF->new( -file => $self->gff_file, -gff_version => 3 );
+ while ( my $feature = $gffio->next_feature() ) {
+ my $gene_id = $self->_get_feature_id($feature);
+ next unless ($gene_id);
+
+ if ( $feature->has_tag('gene') ) {
+ my ( $gene_name, @junk ) = $feature->get_tag_values('gene');
+ $gene_name =~ s!"!!g;
+ if ( $gene_name ne "" ) {
+ $id_to_gene_name{$gene_id} = $gene_name;
+ }
+ }
+ if ( $feature->has_tag('product') ) {
+ my ( $product, @junk ) = $feature->get_tag_values('product');
+ $self->ids_to_product->{$gene_id} = $product;
+ }
+ $self->ids_to_gene_size->{$gene_id} = $feature->end - $feature->start;
+ }
+
+ return \%id_to_gene_name;
+}
+
+sub _get_feature_id {
+ my ( $self, $feature ) = @_;
+ my ( $gene_id, @junk );
+ if ( $feature->has_tag('ID') ) {
+ ( $gene_id, @junk ) = $feature->get_tag_values('ID');
+ }
+ elsif ( $feature->has_tag('locus_tag') ) {
+ ( $gene_id, @junk ) = $feature->get_tag_values('locus_tag');
+ }
+ else {
+ return undef;
+ }
+ $gene_id =~ s!["']!!g;
+ return undef if ( $gene_id eq "" );
+ return $gene_id;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/GroupLabels.pm b/lib/Bio/Roary/GroupLabels.pm
new file mode 100644
index 0000000..bf45f36
--- /dev/null
+++ b/lib/Bio/Roary/GroupLabels.pm
@@ -0,0 +1,62 @@
+package Bio::Roary::GroupLabels;
+
+# ABSTRACT: Add labels to the groups
+
+=head1 SYNOPSIS
+
+Add labels to the groups
+ use Bio::Roary::GroupLabels;
+
+ my $obj = Bio::Roary::GroupLabels->new(
+ groups_filename => 'abc.groups',
+ output_filename => 'output.groups'
+ );
+ $obj->add_labels;
+
+=cut
+
+use Moose;
+use Bio::Roary::Exceptions;
+
+has 'groups_filename' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'output_filename' => ( is => 'ro', isa => 'Str', default => 'labelled_groups_file' );
+
+has '_input_fh' => ( is => 'ro', lazy => 1, builder => '_build__input_fh' );
+has '_output_fh' => ( is => 'ro', lazy => 1, builder => '_build__output_fh' );
+has '_group_default_prefix' => ( is => 'ro', isa => 'Str', default => 'group_' );
+
+sub _build__input_fh {
+ my ($self) = @_;
+ open( my $fh, $self->groups_filename )
+ or Bio::Roary::Exceptions::FileNotFound->throw( error => "Group file not found:" . $self->groups_filename );
+ return $fh;
+}
+
+sub _build__output_fh {
+ my ($self) = @_;
+ open( my $fh, '>', $self->output_filename )
+ or Bio::Roary::Exceptions::CouldntWriteToFile->throw(
+ error => "Couldnt write output file:" . $self->output_filename );
+ return $fh;
+}
+
+sub add_labels {
+ my ($self) = @_;
+
+ my $counter = 1;
+ my $in_fh = $self->_input_fh;
+ while (<$in_fh>) {
+ my $line = $_;
+ next if ( $line eq "" );
+ print { $self->_output_fh } $self->_group_default_prefix . $counter . ": " . $line;
+ $counter++;
+ }
+ close( $self->_input_fh );
+ close( $self->_output_fh );
+ return 1;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/GroupStatistics.pm b/lib/Bio/Roary/GroupStatistics.pm
new file mode 100644
index 0000000..6af9045
--- /dev/null
+++ b/lib/Bio/Roary/GroupStatistics.pm
@@ -0,0 +1,242 @@
+package Bio::Roary::GroupStatistics;
+
+# ABSTRACT: Add labels to the groups
+
+=head1 SYNOPSIS
+
+Add labels to the groups
+ use Bio::Roary::GroupStatistics;
+
+ my $obj = Bio::Roary::GroupStatistics->new(
+ output_filename => 'group_statitics.csv',
+ annotate_groups_obj => $annotate_groups_obj,
+ analyse_groups_obj => $analyse_groups_obj
+ );
+ $obj->create_spreadsheet;
+
+=cut
+
+use Moose;
+use POSIX;
+use Text::CSV;
+use File::Basename;
+use Bio::SeqIO;
+use Bio::Roary::Exceptions;
+use Bio::Roary::AnalyseGroups;
+use Bio::Roary::AnnotateGroups;
+use Bio::Roary::PresenceAbsenceMatrix;
+
+has 'annotate_groups_obj' => ( is => 'ro', isa => 'Bio::Roary::AnnotateGroups', required => 1 );
+has 'analyse_groups_obj' => ( is => 'ro', isa => 'Bio::Roary::AnalyseGroups', required => 1 );
+has 'output_filename' => ( is => 'ro', isa => 'Str', default => 'gene_presence_absence.csv' );
+has 'output_rtab_filename' => ( is => 'ro', isa => 'Str', default => 'gene_presence_absence.Rtab' );
+has 'groups_to_contigs' => ( is => 'ro', isa => 'Maybe[HashRef]');
+has '_output_fh' => ( is => 'ro', lazy => 1, builder => '_build__output_fh' );
+has '_text_csv_obj' => ( is => 'ro', isa => 'Text::CSV', lazy => 1, builder => '_build__text_csv_obj' );
+has '_sorted_file_names' => ( is => 'ro', isa => 'ArrayRef', lazy => 1, builder => '_build__sorted_file_names' );
+has '_groups_to_files' => ( is => 'ro', isa => 'HashRef', lazy => 1, builder => '_build__groups_to_files' );
+has '_files_to_groups' => ( is => 'ro', isa => 'HashRef', lazy => 1, builder => '_build__files_to_groups' );
+has '_num_files_in_groups' => ( is => 'ro', isa => 'HashRef', lazy => 1, builder => '_build__num_files_in_groups' );
+has '_verbose' => ( is => 'ro', isa => 'Bool', default => 0 );
+
+
+sub _build__output_fh {
+ my ($self) = @_;
+ open( my $fh, '>', $self->output_filename )
+ or Bio::Roary::Exceptions::CouldntWriteToFile->throw(
+ error => "Couldnt write output file:" . $self->output_filename );
+ return $fh;
+}
+
+sub _build__text_csv_obj {
+ my ($self) = @_;
+ return Text::CSV->new( { binary => 1, always_quote => 1, eol => "\r\n" } );
+}
+
+sub fixed_headers {
+ my ($self) = @_;
+ my @header =
+ ( 'Gene', 'Non-unique Gene name', 'Annotation', 'No. isolates', 'No. sequences', 'Avg sequences per isolate', 'Genome Fragment','Order within Fragment', 'Accessory Fragment','Accessory Order with Fragment', 'QC','Min group size nuc', 'Max group size nuc', 'Avg group size nuc' );
+ return \@header;
+}
+
+sub _sample_headers
+{
+ my ($self) = @_;
+ my @header;
+ for my $filename ( @{ $self->_sorted_file_names } ) {
+ my $filename_cpy = basename($filename);
+ $filename_cpy =~ s!\.gff\.proteome\.faa!!;
+ push( @header, $filename_cpy );
+ }
+ return \@header;
+}
+
+sub _header {
+ my ($self) = @_;
+ my @header = @{ $self->fixed_headers };
+ push( @header, @{$self->_sample_headers});
+ push( @header, 'Inference' ) if ( $self->_verbose );
+ return \@header;
+}
+
+sub _build__sorted_file_names {
+ my ($self) = @_;
+ my @sorted_file_names = sort( @{ $self->analyse_groups_obj->fasta_files } );
+ return \@sorted_file_names;
+}
+
+sub _non_unique_name_for_group {
+ my ( $self, $annotated_group_name ) = @_;
+ my $duplicate_gene_name = '';
+ my $prefix = $self->annotate_groups_obj->_group_default_prefix;
+ if ( $annotated_group_name =~ /$prefix/ ) {
+ my $non_unique_name_for_group =
+ $self->annotate_groups_obj->_consensus_gene_name_for_group($annotated_group_name);
+ if ( !( $non_unique_name_for_group =~ /$prefix/ ) ) {
+ $duplicate_gene_name = $non_unique_name_for_group;
+ }
+ }
+ return $duplicate_gene_name;
+}
+
+sub _build__groups_to_files {
+ my ($self) = @_;
+ my %groups_to_files;
+ for my $group ( @{ $self->annotate_groups_obj->_groups } ) {
+ my $genes = $self->annotate_groups_obj->_groups_to_id_names->{$group};
+ my %filenames;
+ for my $gene_name ( @{$genes} ) {
+ my $filename = $self->analyse_groups_obj->_genes_to_file->{$gene_name};
+ push( @{ $filenames{$filename} }, $gene_name );
+ }
+ $groups_to_files{$group} = \%filenames;
+ }
+
+ return \%groups_to_files;
+}
+
+sub _build__files_to_groups
+{
+ my ($self) = @_;
+ my %files_to_groups;
+
+ for my $group (keys %{$self->_groups_to_files})
+ {
+ for my $filename (keys %{$self->_groups_to_files->{$group}})
+ {
+ push(@{$files_to_groups{$filename}}, $group);
+ }
+ }
+
+ return \%files_to_groups;
+}
+
+sub _build__num_files_in_groups
+{
+ my ($self) = @_;
+ my %num_files_in_groups;
+ for my $group (@{ $self->annotate_groups_obj->_groups })
+ {
+ my $num_files = $self->analyse_groups_obj->_count_num_files_in_group( $self->annotate_groups_obj->_groups_to_id_names->{$group});
+ $num_files_in_groups{$group} = $num_files;
+ }
+ return \%num_files_in_groups;
+}
+
+sub _row {
+ my ( $self, $group ) = @_;
+ my $genes = $self->annotate_groups_obj->_groups_to_id_names->{$group};
+
+ my $num_isolates_in_group = $self->analyse_groups_obj->_count_num_files_in_group($genes);
+ my $num_sequences_in_group = $#{$genes} + 1;
+ my $avg_sequences_per_isolate = ceil( ( $num_sequences_in_group / $num_isolates_in_group ) * 100 ) / 100;
+
+ my $annotation = $self->annotate_groups_obj->consensus_product_for_id_names($genes);
+ my $annotated_group_name = $self->annotate_groups_obj->_groups_to_consensus_gene_names->{$group};
+
+ my $duplicate_gene_name = $self->_non_unique_name_for_group($annotated_group_name);
+
+ my $genome_number = '';
+ my $qc_comment = '';
+ my $order_within_fragement = '';
+ my $accessory_order_within_fragement = '';
+ my $accessory_genome_number = '';
+ if(defined($self->groups_to_contigs) && defined($self->groups_to_contigs->{$annotated_group_name}))
+ {
+ $genome_number = $self->groups_to_contigs->{$annotated_group_name}->{label};
+ $qc_comment = $self->groups_to_contigs->{$annotated_group_name}->{comment};
+ $order_within_fragement = $self->groups_to_contigs->{$annotated_group_name}->{order};
+
+ $accessory_genome_number = $self->groups_to_contigs->{$annotated_group_name}->{accessory_label};
+ $accessory_order_within_fragement = $self->groups_to_contigs->{$annotated_group_name}->{accessory_order};
+ }
+
+ my $group_size = $self->annotate_groups_obj->group_nucleotide_lengths->{$group};
+
+ my @row = (
+ $annotated_group_name, $duplicate_gene_name, $annotation,
+ $num_isolates_in_group, $num_sequences_in_group, $avg_sequences_per_isolate,$genome_number,$order_within_fragement,$accessory_genome_number,$accessory_order_within_fragement,$qc_comment,$group_size->{min}, $group_size->{max}, $group_size->{average}
+ );
+
+ for(my $i =0; $i < @row; $i++)
+ {
+ if(!defined($row[$i]))
+ {
+ $row[$i] = '';
+ }
+ }
+
+ for my $filename ( @{ $self->_sorted_file_names } ) {
+ my $group_to_file_genes = $self->_groups_to_files->{$group}->{$filename};
+
+ if ( defined($group_to_file_genes) && @{$group_to_file_genes} > 0 ) {
+
+ push( @row, join( "\t", @{$group_to_file_genes} ) );
+ next;
+ }
+ else {
+ push( @row, '' );
+ }
+ }
+
+ ## ADD INFERENCE AND FULL ANNOTATION IF VERBOSE REQUESTED ##
+ if ( $self->_verbose ){
+ my ( $full_annotation, $inference );
+ $row[2] = $self->annotate_groups_obj->full_annotation($group);
+ push( @row, $self->annotate_groups_obj->inference($group) );
+ }
+
+ return \@row;
+}
+
+sub create_rtab
+{
+ my ($self) = @_;
+ my $presence_absence_matrix_obj = Bio::Roary::PresenceAbsenceMatrix->new(
+ output_filename => $self->output_rtab_filename,
+ annotate_groups_obj => $self->annotate_groups_obj,
+ sorted_file_names => $self->_sorted_file_names,
+ groups_to_files => $self->_groups_to_files,
+ num_files_in_groups => $self->_num_files_in_groups,
+ sample_headers => $self->_sample_headers,
+ );
+ $presence_absence_matrix_obj->create_matrix_file;
+ return $self;
+}
+
+sub create_spreadsheet {
+ my ($self) = @_;
+
+ $self->_text_csv_obj->print( $self->_output_fh, $self->_header );
+
+ for my $group (sort {$self->_num_files_in_groups->{$b}<=>$self->_num_files_in_groups->{$a} || $a cmp $b} keys %{$self->_num_files_in_groups}){
+ $self->_text_csv_obj->print( $self->_output_fh, $self->_row($group) );
+ }
+ close( $self->_output_fh );
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/InflateClusters.pm b/lib/Bio/Roary/InflateClusters.pm
new file mode 100644
index 0000000..8051fc3
--- /dev/null
+++ b/lib/Bio/Roary/InflateClusters.pm
@@ -0,0 +1,109 @@
+package Bio::Roary::InflateClusters;
+
+# ABSTRACT: Take the clusters file from cd-hit and use it to inflate the output of MCL
+
+=head1 SYNOPSIS
+
+Take the clusters file from cd-hit and use it to inflate the output of MCL
+ use Bio::Roary::InflateClusters;
+
+ my $obj = Bio::Roary::InflateClusters->new(
+ clusters_filename => 'example.clstr',
+ mcl_filename => 'example.mcl',
+ output_file => 'example.output'
+ );
+ $obj->inflate;
+
+=cut
+
+use Moose;
+use Bio::Roary::Exceptions;
+with 'Bio::Roary::ClustersRole';
+
+has 'mcl_filename' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'output_file' => ( is => 'ro', isa => 'Str', default => 'inflated_results' );
+has '_mcl_fh' => ( is => 'ro',lazy => 1, builder => '_build__mcl_fh' );
+has '_output_fh' => ( is => 'ro',lazy => 1, builder => '_build__output_fh' );
+has 'cdhit_groups_filename' => ( is => 'ro', isa => 'Maybe[Str]' );
+
+sub _build__output_fh
+{
+ my($self) = @_;
+ open(my $fh, '>', $self->output_file) or Bio::Roary::Exceptions::CouldntWriteToFile->throw( error => 'Cant write to file: ' . $self->output_file );
+ return $fh;
+}
+
+sub _build__mcl_fh
+{
+ my($self) = @_;
+ open(my $fh, $self->mcl_filename) or Bio::Roary::Exceptions::FileNotFound->throw( error => 'Cant open file: ' . $self->mcl_filename );
+ return $fh;
+}
+
+sub _inflate_line
+{
+ my($self, $line) = @_;
+ my @inflated_genes;
+ chomp($line);
+ my @gene_names = split(/[\t\s]+/, $line);
+ for my $gene_name (@gene_names)
+ {
+ push(@inflated_genes, $self->_inflate_gene($gene_name));
+ }
+ return join(' ', at inflated_genes);
+}
+
+sub _inflate_gene
+{
+ my($self, $gene_name) = @_;
+ my $inflated_gene = $gene_name;
+ if(defined($self->_clustered_genes->{$gene_name}))
+ {
+ $inflated_gene = $inflated_gene."\t". join("\t",@{$self->_clustered_genes->{$gene_name}});
+ delete($self->_clustered_genes->{$gene_name});
+ }
+ return $inflated_gene;
+}
+
+sub inflate
+{
+ my($self) = @_;
+ my $mcl_fh = $self->_mcl_fh;
+
+ # Inflate genes from cdhit which were sent to mcl
+ while(<$mcl_fh>)
+ {
+ my $line = $_;
+ print { $self->_output_fh } $self->_inflate_line($line) . "\n";
+ }
+
+ # Inflate any clusters that were in the clusters file but not sent to mcl
+ for my $gene_name(keys %{$self->_clustered_genes})
+ {
+ next unless(defined($self->_clustered_genes->{$gene_name}));
+ print { $self->_output_fh } $gene_name."\t". join("\t",@{$self->_clustered_genes->{$gene_name}})."\n";
+ }
+
+ if(defined($self->cdhit_groups_filename))
+ {
+ # Add clusters which were excluded because the groups were full at the cdhit stage
+ open(my $cdhit_fh, $self->cdhit_groups_filename) or Bio::Roary::Exceptions::FileNotFound->throw( error => "CD hit group file not found: " . $self->cdhit_groups_filename);
+ while(<$cdhit_fh>)
+ {
+ my $line = $_;
+
+ if(defined($line))
+ {
+ print { $self->_output_fh } $line ;
+ }
+ }
+ }
+
+ close($self->_output_fh);
+ 1;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/IterativeCdhit.pm b/lib/Bio/Roary/IterativeCdhit.pm
new file mode 100644
index 0000000..702f9ed
--- /dev/null
+++ b/lib/Bio/Roary/IterativeCdhit.pm
@@ -0,0 +1,114 @@
+package Bio::Roary::IterativeCdhit;
+
+# ABSTRACT: Run CDhit iteratively with reducing thresholds, removing full clusters each time
+
+=head1 SYNOPSIS
+
+Run CDhit iteratively with reducing thresholds, removing full clusters each time
+ use Bio::Roary::IterativeCdhit;
+
+ my $obj = Bio::Roary::IterativeCdhit->new(
+ output_cd_hit_filename => 'output_cd_hit_filename.fa',
+ output_combined_filename => 'output_combined_filename.fa',
+ number_of_input_files => 5,
+ output_filtered_clustered_fasta= > 'output_filtered_clustered_fasta.fa',
+ );
+ $obj->run;
+
+=cut
+
+use Moose;
+use Bio::SeqIO;
+use Bio::Roary::Exceptions;
+use Bio::Roary::External::Cdhit;
+use Bio::Roary::FilterFullClusters;
+use File::Copy;
+use Log::Log4perl qw(:easy);
+# CD hit is run locally
+
+has 'output_cd_hit_filename' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'output_combined_filename' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'number_of_input_files' => ( is => 'ro', isa => 'Int', required => 1 );
+has 'output_filtered_clustered_fasta' => ( is => 'ro', isa => 'Str', required => 1 );
+
+has 'lower_bound_percentage' => ( is => 'ro', isa => 'Num', default => 0.98 );
+has 'upper_bound_percentage' => ( is => 'ro', isa => 'Num', default => 0.99 );
+has 'step_size_percentage' => ( is => 'ro', isa => 'Num', default => 0.005 );
+has 'cpus' => ( is => 'ro', isa => 'Int', default => 1 );
+has 'logger' => ( is => 'ro', lazy => 1, builder => '_build_logger');
+
+sub _build_logger
+{
+ my ($self) = @_;
+ Log::Log4perl->easy_init(level => $ERROR);
+ my $logger = get_logger();
+ return $logger;
+}
+
+
+sub run {
+ my ($self) = @_;
+
+ $self->filter_complete_clusters(
+ $self->output_cd_hit_filename,
+ 1,
+ $self->output_combined_filename,
+ $self->number_of_input_files,
+ $self->output_filtered_clustered_fasta, 1
+ );
+
+ for ( my $percent_match = $self->upper_bound_percentage ; $percent_match >= $self->lower_bound_percentage ; $percent_match -= $self->step_size_percentage ) {
+ $self->filter_complete_clusters(
+ $self->output_cd_hit_filename,
+ $percent_match,
+ $self->output_combined_filename,
+ $self->number_of_input_files,
+ $self->output_filtered_clustered_fasta, 0
+ );
+ }
+
+ my $cdhit_obj = Bio::Roary::External::Cdhit->new(
+ input_file => $self->output_combined_filename,
+ output_base => $self->output_cd_hit_filename,
+ _length_difference_cutoff => $self->lower_bound_percentage,
+ _sequence_identity_threshold => $self->lower_bound_percentage,
+ cpus => $self->cpus,
+ logger => $self->logger
+ );
+ $cdhit_obj->run();
+ return $cdhit_obj->clusters_filename;
+}
+
+sub filter_complete_clusters {
+ my ( $self, $output_cd_hit_filename, $percentage_match, $output_combined_filename, $number_of_input_files,
+ $output_filtered_clustered_fasta,
+ $greater_than_or_equal )
+ = @_;
+ my $cdhit_obj = Bio::Roary::External::Cdhit->new(
+ input_file => $output_combined_filename,
+ output_base => $output_cd_hit_filename,
+ _length_difference_cutoff => $percentage_match,
+ _sequence_identity_threshold => $percentage_match,
+ cpus => $self->cpus,
+ );
+ $cdhit_obj->run();
+
+ my $filter_clusters = Bio::Roary::FilterFullClusters->new(
+ clusters_filename => $cdhit_obj->clusters_filename,
+ fasta_file => $output_cd_hit_filename,
+ number_of_input_files => $number_of_input_files,
+ output_file => $output_filtered_clustered_fasta,
+ _greater_than_or_equal => $greater_than_or_equal,
+ cdhit_input_fasta_file => $output_combined_filename,
+ cdhit_output_fasta_file => $output_combined_filename . '.filtered',
+ output_groups_file => $output_combined_filename . '.groups'
+ );
+
+ $filter_clusters->filter_complete_cluster_from_original_fasta();
+ move( $filter_clusters->cdhit_output_fasta_file, $output_combined_filename );
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/JobRunner/Local.pm b/lib/Bio/Roary/JobRunner/Local.pm
new file mode 100644
index 0000000..b0960ea
--- /dev/null
+++ b/lib/Bio/Roary/JobRunner/Local.pm
@@ -0,0 +1,64 @@
+package Bio::Roary::JobRunner::Local;
+
+# ABSTRACT: Execute a set of commands locally
+
+=head1 SYNOPSIS
+
+ Execute a set of commands locally
+ use Bio::Roary::JobRunner::Local;
+
+ my $obj = Bio::Roary::JobRunner::Local->new(
+ commands_to_run => ['ls', 'echo "abc"'],
+ );
+ $obj->run();
+
+=cut
+
+use Moose;
+use Log::Log4perl qw(:easy);
+
+has 'commands_to_run' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'logger' => ( is => 'ro', lazy => 1, builder => '_build_logger');
+has 'verbose' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'memory_in_mb' => ( is => 'rw', isa => 'Int', default => '200' );
+
+sub run {
+ my ($self) = @_;
+
+ for my $command_to_run ( @{ $self->commands_to_run } ) {
+ $self->logger->info($command_to_run);
+ system($command_to_run );
+ }
+ 1;
+}
+
+
+sub _construct_dependancy_params
+{
+ my ($self) = @_;
+ return '';
+}
+
+sub submit_dependancy_job {
+ my ( $self,$command_to_run) = @_;
+ $self->logger->info($command_to_run);
+ system($command_to_run );
+}
+
+sub _build_logger
+{
+ my ($self) = @_;
+ my $level = $ERROR;
+ if($self->verbose)
+ {
+ $level = $DEBUG;
+ }
+ Log::Log4perl->easy_init($level);
+ my $logger = get_logger();
+ return $logger;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/JobRunner/Parallel.pm b/lib/Bio/Roary/JobRunner/Parallel.pm
new file mode 100644
index 0000000..0660384
--- /dev/null
+++ b/lib/Bio/Roary/JobRunner/Parallel.pm
@@ -0,0 +1,69 @@
+package Bio::Roary::JobRunner::Parallel;
+
+# ABSTRACT: Use GNU Parallel
+
+=head1 SYNOPSIS
+
+ Execute a set of commands using GNU parallel
+ use Bio::Roary::JobRunner::Parallel;
+
+ my $obj = Bio::Roary::JobRunner::Local->new(
+ commands_to_run => ['ls', 'echo "abc"'],
+ max_jobs => 4
+ );
+ $obj->run();
+
+=cut
+
+use Moose;
+use File::Temp qw/ tempfile /;
+use Log::Log4perl qw(:easy);
+
+has 'commands_to_run' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'cpus' => ( is => 'ro', isa => 'Int', default => 1 );
+has 'logger' => ( is => 'ro', lazy => 1, builder => '_build_logger');
+has 'verbose' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'memory_in_mb' => ( is => 'rw', isa => 'Int', default => '200' );
+
+sub run {
+ my ($self) = @_;
+
+ for my $command_to_run(@{ $self->commands_to_run })
+ {
+ $self->logger->info($command_to_run);
+ }
+ open(my $fh,"|-","parallel --gnu -j ".$self->cpus) || die "GNU Parallel failed";
+ print $fh join("\n", @{ $self->commands_to_run });
+ close $fh;
+ 1;
+}
+
+sub _construct_dependancy_params
+{
+ my ($self) = @_;
+ return '';
+}
+
+sub submit_dependancy_job {
+ my ( $self,$command_to_run) = @_;
+ $self->logger->info($command_to_run);
+ system($command_to_run );
+}
+
+sub _build_logger
+{
+ my ($self) = @_;
+ my $level = $ERROR;
+ if($self->verbose)
+ {
+ $level = $DEBUG;
+ }
+ Log::Log4perl->easy_init($level);
+ my $logger = get_logger();
+ return $logger;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/JobRunner/Role.pm b/lib/Bio/Roary/JobRunner/Role.pm
new file mode 100644
index 0000000..f8f44e0
--- /dev/null
+++ b/lib/Bio/Roary/JobRunner/Role.pm
@@ -0,0 +1,65 @@
+package Bio::Roary::JobRunner::Role;
+
+# ABSTRACT: A role to add job runner functionality
+
+=head1 SYNOPSIS
+
+A role to add job runner functionality
+ with 'Bio::Roary::JobRunner::Role';
+
+=cut
+
+use Moose::Role;
+use Log::Log4perl qw(:easy);
+use File::Spec;
+
+has 'job_runner' => ( is => 'rw', isa => 'Str', default => 'Local' );
+has '_job_runner_class' => ( is => 'ro', isa => 'Str', lazy => 1, builder => '_build__job_runner_class' );
+has 'memory_in_mb' => ( is => 'rw', isa => 'Int', default => '200' );
+has '_queue' => ( is => 'rw', isa => 'Str', default => 'normal' );
+has 'dont_wait' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'cpus' => ( is => 'ro', isa => 'Int', default => 1 );
+has 'logger' => ( is => 'ro', lazy => 1, builder => '_build_logger');
+has 'verbose' => ( is => 'rw', isa => 'Bool', default => 0 );
+
+sub _build_logger
+{
+ my ($self) = @_;
+ my $level = $ERROR;
+ if($self->verbose)
+ {
+ $level = $DEBUG;
+ }
+ Log::Log4perl->easy_init($level);
+ my $logger = get_logger();
+ return $logger;
+}
+
+sub _build__job_runner_class {
+ my ($self) = @_;
+ my $job_runner_class = "Bio::Roary::JobRunner::" . $self->job_runner;
+ eval "require $job_runner_class";
+ return $job_runner_class;
+}
+
+sub _find_exe {
+ my($self,$executables) = @_;
+
+ # If there is an explicit full path passed in, just return.
+ if($executables->[0] =~ m!/!)
+ {
+ return $executables->[0];
+ }
+
+ for my $dir (File::Spec->path) {
+ for my $exec (@{$executables})
+ {
+ my $exe = File::Spec->catfile($dir, $exec);
+ return $exe if -x $exe;
+ }
+ }
+ return $executables->[0];
+}
+
+
+1;
diff --git a/lib/Bio/Roary/LookupGeneFiles.pm b/lib/Bio/Roary/LookupGeneFiles.pm
new file mode 100644
index 0000000..7821f61
--- /dev/null
+++ b/lib/Bio/Roary/LookupGeneFiles.pm
@@ -0,0 +1,53 @@
+package Bio::Roary::LookupGeneFiles;
+
+# ABSTRACT: Take in an ordering of genes and a directory and return an ordered list of file locations
+
+=head1 SYNOPSIS
+
+Take in an ordering of genes and a directory and return an ordered list of file locations
+ use Bio::Roary::LookupGeneFiles;
+
+ my $obj = Bio::Roary::LookupGeneFiles->new(
+ multifasta_directory => 'pan_genome_sequences',
+ ordered_genes => ['gene5','gene2','gene3'],
+
+ );
+ $obj->ordered_gene_files();
+
+=cut
+
+use Moose;
+
+has 'multifasta_directory' => ( is => 'ro', isa => 'Str', default => 'pan_genome_sequences' );
+has 'ordered_genes' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+
+has 'ordered_gene_files' => ( is => 'ro', isa => 'ArrayRef', lazy => 1, builder => '_build_ordered_gene_files' );
+
+
+sub _build_ordered_gene_files
+{
+ my ($self) = @_;
+ my @gene_files;
+ for my $gene (@{$self->ordered_genes})
+ {
+ $gene =~ s!\W!_!gi;
+ my $filename = $gene.'.fa.aln';
+ my $gene_filepath = join('/',($self->multifasta_directory, $filename));
+
+ if(! -e $gene_filepath)
+ {
+ print "Core gene file missing: ". $gene_filepath."\n";
+ }
+ else
+ {
+ push(@gene_files, $gene_filepath);
+ }
+ }
+ return \@gene_files;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
+
diff --git a/lib/Bio/Roary/MergeMultifastaAlignments.pm b/lib/Bio/Roary/MergeMultifastaAlignments.pm
new file mode 100644
index 0000000..d2dd55e
--- /dev/null
+++ b/lib/Bio/Roary/MergeMultifastaAlignments.pm
@@ -0,0 +1,121 @@
+package Bio::Roary::MergeMultifastaAlignments;
+
+# ABSTRACT: Merge multifasta alignment files with equal numbers of sequences.
+
+=head1 SYNOPSIS
+
+Merge multifasta alignment files with equal numbers of sequences.So each sequence in each file gets concatenated together. It is assumed the
+sequences are in the correct order.
+ use Bio::Roary::MergeMultifastaAlignments;
+
+ my $obj = Bio::Roary::MergeMultifastaAlignments->new(
+ multifasta_files => [],
+ output_filename => 'output_merged.aln'
+ );
+ $obj->merge_files;
+
+=cut
+
+use Moose;
+use Bio::SeqIO;
+use Bio::Roary::Output::CoreGeneAlignmentCoordinatesEMBL;
+
+has 'multifasta_files' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'sample_names' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'sample_names_to_genes' => ( is => 'rw', isa => 'HashRef', required => 1 );
+has 'output_filename' => ( is => 'ro', isa => 'Str', default => 'core_alignment.aln' );
+has 'output_header_filename' => ( is => 'ro', isa => 'Str', default => 'core_alignment_header.embl' );
+has '_output_seqio_obj' => ( is => 'ro', isa => 'Bio::SeqIO', lazy => 1, builder => '_build__output_seqio_obj' );
+has '_gene_lengths' => ( is => 'rw', isa => 'HashRef', lazy => 1, builder => '_build__gene_lengths' );
+has '_gene_to_sequence' => ( is => 'rw', isa => 'HashRef', default => sub { {} } );
+has '_sorted_multifasta_files' => ( is => 'rw', isa => 'ArrayRef', lazy => 1, builder => '_build__sorted_multifasta_files' );
+
+sub BUILD {
+ my ($self) = @_;
+ $self->_gene_lengths;
+}
+
+sub _input_seq_io_obj {
+ my ( $self, $filename ) = @_;
+ return Bio::SeqIO->new( -file => $filename, -format => 'Fasta' );
+}
+
+sub _build__output_seqio_obj {
+ my ($self) = @_;
+ return Bio::SeqIO->new( -file => ">" . $self->output_filename, -format => 'Fasta' );
+}
+
+sub _build__gene_lengths {
+ my ($self) = @_;
+ my %gene_lengths;
+ for my $filename ( @{ $self->_sorted_multifasta_files } ) {
+ my $seq_io = $self->_input_seq_io_obj($filename);
+ next unless ( defined($seq_io) );
+ while ( my $seq_record = $seq_io->next_seq ) {
+
+ # Save all of the gene sequences to memory, massive speedup but a bit naughty.
+ $self->_gene_to_sequence->{$filename}->{ $seq_record->display_id } = $seq_record->seq;
+ $gene_lengths{$filename} = $seq_record->length() if ( !defined( $gene_lengths{$filename} ) );
+ }
+ }
+
+ return \%gene_lengths;
+}
+
+sub _build__sorted_multifasta_files {
+ my ($self) = @_;
+ my @sorted_gene_files = sort @{ $self->multifasta_files };
+ return \@sorted_gene_files;
+}
+
+sub _sequence_for_sample_from_gene_file {
+ my ( $self, $sample_name, $gene_file ) = @_;
+
+ # loop over this to get the geneIDs
+ for my $gene_id ( keys %{ $self->_gene_to_sequence->{$gene_file} } ) {
+ if ( defined( $self->sample_names_to_genes->{$sample_name}->{$gene_id} ) ) {
+ return $self->_gene_to_sequence->{$gene_file}->{$gene_id};
+ }
+ }
+ return $self->_padded_string_for_gene_file($gene_file);
+}
+
+sub _padded_string_for_gene_file {
+ my ( $self, $gene_file ) = @_;
+ return '' unless ( defined( $self->_gene_lengths->{$gene_file} ) );
+ return 'N' x ( $self->_gene_lengths->{$gene_file} );
+}
+
+sub _create_merged_sequence_for_sample {
+ my ( $self, $sample_name ) = @_;
+ my $merged_sequence = '';
+ for my $gene_file ( @{ $self->_sorted_multifasta_files } ) {
+ $merged_sequence .= $self->_sequence_for_sample_from_gene_file( $sample_name, $gene_file );
+ }
+ return $merged_sequence;
+}
+
+sub merge_files {
+ my ($self) = @_;
+
+ for my $sample_name ( @{ $self->sample_names } ) {
+ my $sequence = $self->_create_merged_sequence_for_sample($sample_name);
+ my $seq_io = Bio::Seq->new( -display_id => $sample_name, -seq => $sequence );
+ $self->_output_seqio_obj->write_seq($seq_io);
+ }
+
+ # Create a header file which gives the coordinates of each gene in the multifasta
+ Bio::Roary::Output::CoreGeneAlignmentCoordinatesEMBL->new(
+ multifasta_files => $self->_sorted_multifasta_files,
+ gene_lengths => $self->_gene_lengths,
+ output_filename => $self->output_header_filename
+ )->create_file();
+
+ return 1;
+}
+
+no Moose;
+ __PACKAGE__->meta->make_immutable;
+
+1;
+
diff --git a/lib/Bio/Roary/OrderGenes.pm b/lib/Bio/Roary/OrderGenes.pm
new file mode 100644
index 0000000..e4652c2
--- /dev/null
+++ b/lib/Bio/Roary/OrderGenes.pm
@@ -0,0 +1,391 @@
+package Bio::Roary::OrderGenes;
+
+# ABSTRACT: Take in GFF files and create a matrix of what genes are beside what other genes
+
+=head1 SYNOPSIS
+
+Take in the analyse groups and create a matrix of what genes are beside what other genes
+ use Bio::Roary::OrderGenes;
+
+ my $obj = Bio::Roary::OrderGenes->new(
+ analyse_groups_obj => $analyse_groups_obj,
+ gff_files => ['file1.gff','file2.gff']
+ );
+ $obj->groups_to_contigs;
+
+=cut
+
+use Moose;
+use Bio::Roary::Exceptions;
+use Bio::Roary::AnalyseGroups;
+use Bio::Roary::ContigsToGeneIDsFromGFF;
+use Graph;
+use Graph::Writer::Dot;
+use File::Basename;
+
+has 'gff_files' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'analyse_groups_obj' => ( is => 'ro', isa => 'Bio::Roary::AnalyseGroups', required => 1 );
+has 'core_definition' => ( is => 'ro', isa => 'Num', default => 1.0 );
+has 'pan_graph_filename' => ( is => 'ro', isa => 'Str', default => 'core_accessory_graph.dot' );
+has 'accessory_graph_filename' => ( is => 'ro', isa => 'Str', default => 'accessory_graph.dot' );
+has 'sample_weights' => ( is => 'ro', isa => 'Maybe[HashRef]' );
+has 'samples_to_clusters' => ( is => 'ro', isa => 'Maybe[HashRef]' );
+has 'group_order' => ( is => 'ro', isa => 'HashRef', lazy => 1, builder => '_build_group_order' );
+has 'groups_to_sample_names' => ( is => 'rw', isa => 'HashRef', default => sub { {} } );
+has 'group_graphs' => ( is => 'ro', isa => 'Graph', lazy => 1, builder => '_build_group_graphs' );
+has 'groups_to_contigs' => ( is => 'ro', isa => 'HashRef', lazy => 1, builder => '_build_groups_to_contigs' );
+has '_groups_to_file_contigs' => ( is => 'ro', isa => 'HashRef', lazy => 1, builder => '_build__groups_to_file_contigs' );
+has '_groups' => ( is => 'ro', isa => 'HashRef', lazy => 1, builder => '_build_groups' );
+has 'number_of_files' => ( is => 'ro', isa => 'Int', lazy => 1, builder => '_build_number_of_files' );
+has '_groups_qc' => ( is => 'ro', isa => 'HashRef', default => sub { {} } );
+has '_percentage_of_largest_weak_threshold' => ( is => 'ro', isa => 'Num', default => 0.9 );
+
+sub _build_number_of_files {
+ my ($self) = @_;
+ return @{ $self->gff_files };
+}
+
+sub _build_groups {
+ my ($self) = @_;
+ my %groups;
+ for my $group_name ( @{ $self->analyse_groups_obj->_groups } ) {
+ $groups{$group_name}++;
+ }
+ return \%groups;
+}
+
+sub _build__groups_to_file_contigs {
+ my ($self) = @_;
+
+ my @overlapping_hypothetical_gene_ids;
+ my %samples_to_groups_contigs;
+
+ # Open each GFF file
+ for my $filename ( @{ $self->gff_files } ) {
+ my @groups_to_contigs;
+ my $contigs_to_ids_obj = Bio::Roary::ContigsToGeneIDsFromGFF->new( gff_file => $filename );
+
+ my ( $sample_name, $directories, $suffix ) = fileparse($filename);
+ $sample_name =~ s/\.gff//gi;
+
+ # Loop over each contig in the GFF file
+ for my $contig_name ( keys %{ $contigs_to_ids_obj->contig_to_ids } ) {
+ my @groups_on_contig;
+
+ # loop over each gene in each contig in the GFF file
+ for my $gene_id ( @{ $contigs_to_ids_obj->contig_to_ids->{$contig_name} } ) {
+
+ # convert to group name
+ my $group_name = $self->analyse_groups_obj->_genes_to_groups->{$gene_id};
+ next unless ( defined($group_name) );
+
+ if ( $contigs_to_ids_obj->overlapping_hypothetical_protein_ids->{$gene_id} ) {
+ $self->_groups_qc->{$group_name} =
+'Hypothetical protein with no hits to refseq/uniprot/clusters/cdd/tigrfams/pfam overlapping another protein with hits';
+ }
+ push( @groups_on_contig, $group_name );
+ }
+ push( @groups_to_contigs, \@groups_on_contig );
+ }
+ $samples_to_groups_contigs{$sample_name} = \@groups_to_contigs;
+ }
+
+ return \%samples_to_groups_contigs;
+
+}
+
+sub _build_group_order {
+ my ($self) = @_;
+ my %group_order;
+
+ my %groups_to_sample_names;
+ for my $sample_name ( keys %{ $self->_groups_to_file_contigs } ) {
+ my $groups_to_file_contigs = $self->_groups_to_file_contigs->{$sample_name};
+ for my $groups_on_contig ( @{$groups_to_file_contigs} ) {
+ for ( my $i = 1 ; $i < @{$groups_on_contig} ; $i++ ) {
+ my $group_from = $groups_on_contig->[ $i - 1 ];
+ my $group_to = $groups_on_contig->[$i];
+
+ if ( defined( $self->sample_weights ) && $self->sample_weights->{$sample_name} ) {
+ $group_order{$group_from}{$group_to} += $self->sample_weights->{$sample_name};
+ push( @{ $groups_to_sample_names{$group_from} }, $sample_name );
+ }
+ else {
+ $group_order{$group_from}{$group_to}++;
+ }
+ }
+ if ( @{$groups_on_contig} == 1 ) {
+ my $group_from = $groups_on_contig->[0];
+ my $group_to = $groups_on_contig->[0];
+ if ( defined( $self->sample_weights ) && $self->sample_weights->{$sample_name} ) {
+ $group_order{$group_from}{$group_to} += $self->sample_weights->{$sample_name};
+ push( @{ $groups_to_sample_names{$group_from} }, $sample_name );
+ }
+ else {
+ $group_order{$group_from}{$group_to}++;
+ }
+ }
+ }
+ }
+
+ $self->groups_to_sample_names( \%groups_to_sample_names );
+ return \%group_order;
+}
+
+sub _build_group_graphs {
+ my ($self) = @_;
+ return Graph->new( undirected => 1 );
+}
+
+sub _save_graph_to_file {
+ my ( $self, $graph, $output_filename ) = @_;
+ my $writer = Graph::Writer::Dot->new();
+ $writer->write_graph( $graph, $output_filename );
+ return 1;
+}
+
+sub _add_groups_to_graph {
+ my ($self) = @_;
+
+ for my $current_group ( keys %{ $self->group_order() } ) {
+ for my $group_to ( keys %{ $self->group_order->{$current_group} } ) {
+ my $weight = 1.0 / ( $self->group_order->{$current_group}->{$group_to} );
+ $self->group_graphs->add_weighted_edge( $current_group, $group_to, $weight );
+ }
+ }
+
+}
+
+sub _reorder_connected_components {
+ my ( $self, $graph_groups ) = @_;
+ my @ordered_graph_groups;
+ my @paths_and_weights;
+
+ for my $graph_group ( @{$graph_groups} ) {
+ my %groups;
+ $groups{$_}++ for ( @{$graph_group} );
+ my $edge_sum = 0;
+
+ for my $current_group ( keys %groups ) {
+ for my $group_to ( keys %{ $self->group_order->{$current_group} } ) {
+ next unless defined( $groups{$group_to} );
+ $edge_sum += $self->group_order->{$current_group}->{$group_to};
+ }
+ }
+
+ my %samples_in_graph;
+ for my $current_group ( keys %groups ) {
+ my $sample_names = $self->groups_to_sample_names->{$current_group};
+ if ( defined($sample_names) ) {
+ for my $sample_name ( @{$sample_names} ) {
+ $samples_in_graph{$sample_name}++;
+ }
+ }
+ }
+ my @sample_names = sort keys %samples_in_graph;
+
+ if ( @{$graph_group} == 1 ) {
+
+ push(
+ @paths_and_weights,
+ {
+ path => $graph_group,
+ average_weight => $edge_sum,
+ sample_names => \@sample_names
+ }
+ );
+ }
+ else {
+ my $graph = Graph->new( undirected => 1 );
+ for my $current_group ( keys %groups ) {
+ for my $group_to ( keys %{ $self->group_order->{$current_group} } ) {
+ if ( $groups{$group_to} ) {
+ my $weight = 1 / $self->group_order->{$current_group}->{$group_to};
+ $graph->add_weighted_edge( $current_group, $group_to, $weight );
+ }
+ }
+ }
+ my $minimum_spanning_tree = $graph->minimum_spanning_tree;
+ my $dfs_obj = Graph::Traversal::DFS->new($minimum_spanning_tree);
+ my @reordered_dfs_groups = $dfs_obj->dfs;
+ push(
+ @paths_and_weights,
+ {
+ path => \@reordered_dfs_groups,
+ average_weight => $edge_sum,
+ sample_names => \@sample_names
+ }
+ );
+ }
+
+ }
+
+ return $self->_order_by_samples_and_weights( \@paths_and_weights );
+}
+
+sub _order_by_samples_and_weights {
+ my ( $self, $paths_and_weights ) = @_;
+
+ my @ordered_graph_groups;
+ if ( !defined( $self->samples_to_clusters ) ) {
+ my @ordered_paths_and_weights = sort { $a->{average_weight} <=> $b->{average_weight} } @{$paths_and_weights};
+ @ordered_graph_groups = map { $_->{path} } @ordered_paths_and_weights;
+ return \@ordered_graph_groups;
+ }
+
+ # Find the largest cluster in each graph and regroup
+ my %largest_cluster_to_paths_and_weights;
+ for my $graph_details ( @{$paths_and_weights} ) {
+ my %cluster_count;
+ for my $sample_name ( @{ $graph_details->{sample_names} } ) {
+ if ( defined( $self->samples_to_clusters->{$sample_name} ) ) {
+ $cluster_count{ $self->samples_to_clusters->{$sample_name} }++;
+ }
+ }
+ my $largest_cluster = ( sort { $cluster_count{$b} <=> $cluster_count{$a} || $a cmp $b} keys %cluster_count )[0];
+ if ( !defined($largest_cluster) ) {
+ my @ordered_paths_and_weights = sort { $b->{average_weight} <=> $a->{average_weight} } @{$paths_and_weights};
+ @ordered_graph_groups = map { $_->{path} } @ordered_paths_and_weights;
+ return \@ordered_graph_groups;
+ }
+
+ push( @{ $largest_cluster_to_paths_and_weights{$largest_cluster}{graph_details} }, $graph_details );
+ $largest_cluster_to_paths_and_weights{$largest_cluster}{largest_cluster_size} += $cluster_count{$largest_cluster};
+ }
+
+ # go through each cluster group and order by weight
+ my @clustered_ordered_graph_groups;
+ for my $cluster_name (
+ sort {
+ $largest_cluster_to_paths_and_weights{$b}->{largest_cluster_size}
+ <=> $largest_cluster_to_paths_and_weights{$a}->{largest_cluster_size}
+ } keys %largest_cluster_to_paths_and_weights
+ )
+ {
+
+ my @ordered_paths_and_weights =
+ sort { $b->{average_weight} <=> $a->{average_weight} } @{ $largest_cluster_to_paths_and_weights{$cluster_name}->{graph_details} };
+ @ordered_graph_groups = map { $_->{path} } @ordered_paths_and_weights;
+
+ for my $graph_group (@ordered_graph_groups) {
+ push( @clustered_ordered_graph_groups, $graph_group );
+ }
+ }
+ return \@clustered_ordered_graph_groups;
+}
+
+sub _build_groups_to_contigs {
+ my ($self) = @_;
+ $self->_add_groups_to_graph;
+
+ my %groups_to_contigs;
+ my $counter = 1;
+ my $overall_counter = 1;
+ my $counter_filtered = 1;
+
+ # Accessory
+ my $accessory_graph = $self->_create_accessory_graph;
+ my @group_graphs = $accessory_graph->connected_components();
+ my $reordered_graphs = $self->_reorder_connected_components( \@group_graphs );
+
+ $self->_save_graph_to_file( $accessory_graph, $self->accessory_graph_filename );
+
+ for my $contig_groups ( @{$reordered_graphs} ) {
+ my $order_counter = 1;
+
+ for my $group_name ( @{$contig_groups} ) {
+ $groups_to_contigs{$group_name}{accessory_label} = $counter;
+ $groups_to_contigs{$group_name}{accessory_order} = $order_counter;
+ $groups_to_contigs{$group_name}{'accessory_overall_order'} = $overall_counter;
+ $order_counter++;
+ $overall_counter++;
+ }
+ $counter++;
+ }
+
+ # Core + accessory
+ my @group_graphs_all = $self->group_graphs->connected_components();
+ my $reordered_graphs_all = $self->_reorder_connected_components( \@group_graphs_all );
+ $self->_save_graph_to_file( $self->group_graphs, $self->pan_graph_filename );
+
+ $overall_counter = 1;
+ $counter = 1;
+ $counter_filtered = 1;
+ for my $contig_groups ( @{$reordered_graphs_all} ) {
+ my $order_counter = 1;
+
+ for my $group_name ( @{$contig_groups} ) {
+ $groups_to_contigs{$group_name}{label} = $counter;
+ $groups_to_contigs{$group_name}{comment} = '';
+ $groups_to_contigs{$group_name}{order} = $order_counter;
+ $groups_to_contigs{$group_name}{'core_accessory_overall_order'} = $overall_counter;
+
+ if ( @{$contig_groups} <= 2 ) {
+ $groups_to_contigs{$group_name}{comment} = 'Investigate';
+ }
+ elsif ( $self->_groups_qc->{$group_name} ) {
+ $groups_to_contigs{$group_name}{comment} = $self->_groups_qc->{$group_name};
+ }
+ else {
+ $groups_to_contigs{$group_name}{'core_accessory_overall_order_filtered'} = $counter_filtered;
+ $counter_filtered++;
+ }
+ $order_counter++;
+ $overall_counter++;
+ }
+ $counter++;
+ }
+
+ $counter_filtered = 1;
+ for my $contig_groups ( @{$reordered_graphs} ) {
+ for my $group_name ( @{$contig_groups} ) {
+ if ( ( !defined( $groups_to_contigs{$group_name}{comment} ) )
+ || ( defined( $groups_to_contigs{$group_name}{comment} ) && $groups_to_contigs{$group_name}{comment} eq '' ) )
+ {
+ $groups_to_contigs{$group_name}{'accessory_overall_order_filtered'} = $counter_filtered;
+ $counter_filtered++;
+ }
+ }
+ }
+
+ return \%groups_to_contigs;
+}
+
+sub _create_accessory_graph {
+ my ($self) = @_;
+ my $graph = Graph->new( undirected => 1 );
+
+ my %core_groups;
+ my %group_freq;
+
+ for my $sample_name ( keys %{ $self->_groups_to_file_contigs } ) {
+ my $groups_to_file_contigs = $self->_groups_to_file_contigs->{$sample_name};
+
+ for my $groups_on_contig ( @{$groups_to_file_contigs} ) {
+ for my $current_group ( @{$groups_on_contig} ) {
+ $group_freq{$current_group}++;
+ }
+ }
+ }
+
+ for my $current_group ( keys %{ $self->group_order() } ) {
+ next if ( $group_freq{$current_group} >= ( $self->number_of_files * $self->core_definition ) );
+
+ for my $group_to ( keys %{ $self->group_order->{$current_group} } ) {
+ if ( $group_freq{$group_to} >= ( $self->number_of_files * $self->core_definition ) ) {
+ $graph->add_vertex($current_group);
+ }
+ else {
+ my $weight = 1.0 / ( $self->group_order->{$current_group}->{$group_to} );
+ $graph->add_weighted_edge( $current_group, $group_to, $weight );
+ }
+ }
+ }
+
+ return $graph;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/Output/BlastIdentityFrequency.pm b/lib/Bio/Roary/Output/BlastIdentityFrequency.pm
new file mode 100644
index 0000000..cf3512e
--- /dev/null
+++ b/lib/Bio/Roary/Output/BlastIdentityFrequency.pm
@@ -0,0 +1,62 @@
+package Bio::Roary::Output::BlastIdentityFrequency;
+
+# ABSTRACT: Take in blast results and find the percentage identity graph
+
+=head1 SYNOPSIS
+
+Take in blast results and find the percentage identity graph
+ use Bio::Roary::Output::BlastIdentityFrequency;
+
+ my $obj = Bio::Roary::Output::BlastIdentityFrequency->new(
+ input_filename => '_blast_results',
+ output_filename => 'blast_identity_frequency.Rtab',
+ );
+ $obj->create_file();
+
+=cut
+
+use Moose;
+use Bio::SeqIO;
+use Bio::Roary::Exceptions;
+
+has 'input_filename' => ( is => 'ro', isa => 'Str', default => '_blast_results' );
+has 'output_filename' => ( is => 'ro', isa => 'Str', default => 'blast_identity_frequency.Rtab' );
+
+has '_output_fh' => ( is => 'ro', lazy => 1, builder => '_build__output_fh' );
+has '_input_fh' => ( is => 'ro', lazy => 1, builder => '_build__input_fh' );
+
+sub _build__output_fh
+{
+ my ($self) = @_;
+ open( my $fh, '>', $self->output_filename )
+ or Bio::Roary::Exceptions::CouldntWriteToFile->throw(
+ error => "Couldnt write output file:" . $self->output_filename );
+ return $fh;
+}
+
+sub _build__input_fh
+{
+ my ($self) = @_;
+ my $input_string = 'awk \'{print $3}\' '.$self->input_filename.' | awk \'BEGIN {FS="."}; {print $1}\'| sort | uniq -c | awk \'{print $2"\t"$1}\'';
+
+ open( my $fh, '-|', $input_string ) or die "Couldnt open results file";
+ return $fh;
+}
+
+sub create_file
+{
+ my ($self) = @_;
+
+ my $input_fh = $self->_input_fh;
+ while(<$input_fh>)
+ {
+ print {$self->_output_fh} $_;
+ }
+ close($self->_input_fh);
+ close($self->_output_fh);
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/Output/CoreGeneAlignmentCoordinatesEMBL.pm b/lib/Bio/Roary/Output/CoreGeneAlignmentCoordinatesEMBL.pm
new file mode 100644
index 0000000..a2b2761
--- /dev/null
+++ b/lib/Bio/Roary/Output/CoreGeneAlignmentCoordinatesEMBL.pm
@@ -0,0 +1,81 @@
+package Bio::Roary::Output::CoreGeneAlignmentCoordinatesEMBL;
+
+# ABSTRACT: Create an embl file for the header with locations of where genes are in the multifasta alignment of core genes
+
+=head1 SYNOPSIS
+
+Create an embl file for the header with locations of where genes are in the multifasta alignment of core genes
+ use Bio::Roary::Output::CoreGeneAlignmentCoordinatesEMBL;
+
+ my $obj = Bio::Roary::Output::CoreGeneAlignmentCoordinatesEMBL->new(
+ output_filename => 'core_alignment_header.embl',
+ multifasta_files => [
+ 't/data/multifasta_files/1.aln', 't/data/multifasta_files/outof_order.aln',
+ 't/data/multifasta_files/2.aln', 't/data/multifasta_files/3.aln'
+ ],
+ gene_lengths => {
+ 't/data/multifasta_files/1.aln' => 1,
+ 't/data/multifasta_files/outof_order.aln' => 10,
+ 't/data/multifasta_files/2.aln' => 100,
+ 't/data/multifasta_files/3.aln' => 1000
+ },
+ );
+ $obj->create_file;
+
+=cut
+
+use Moose;
+use Bio::Roary::Exceptions;
+use File::Basename;
+with 'Bio::Roary::Output::EMBLHeaderCommon';
+
+has 'output_filename' => ( is => 'ro', isa => 'Str', default => 'core_alignment_header.embl' );
+has 'multifasta_files' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'gene_lengths' => ( is => 'ro', isa => 'HashRef', required => 1 );
+has '_current_coordinate' => ( is => 'rw', isa => 'Int', default => 1 );
+has '_output_fh' => ( is => 'ro', lazy => 1, builder => '_build__output_fh' );
+
+sub _build__output_fh {
+ my ($self) = @_;
+ open( my $fh, '>', $self->output_filename )
+ or Bio::Roary::Exceptions::CouldntWriteToFile->throw( error => "Couldnt write output file:" . $self->output_filename );
+ return $fh;
+}
+
+sub _gene_name_from_filename {
+ my ( $self, $filename ) = @_;
+ my $gene_name = basename($filename);
+ $gene_name =~ s!\.aln!!;
+ $gene_name =~ s!\.fa!!;
+ return $gene_name;
+}
+
+sub _header_block {
+ my ( $self, $gene_filename ) = @_;
+ my $gene_name = $self->_gene_name_from_filename($gene_filename);
+ my $gene_length = $self->gene_lengths->{$gene_filename};
+ my $end_coordinate = $self->_current_coordinate + $gene_length - 1;
+ my $annotation_type = $self->_annotation_type($gene_name);
+
+ my $tab_file_entry = join( '', ( 'FT', $annotation_type, $self->_current_coordinate, '..', $end_coordinate, "\n" ) );
+ $tab_file_entry .= "FT /label=$gene_name\n";
+ $tab_file_entry .= "FT /locus_tag=$gene_name\n";
+
+ $self->_current_coordinate( $end_coordinate + 1 );
+ return $tab_file_entry;
+}
+
+sub create_file {
+ my ($self) = @_;
+ print { $self->_output_fh } $self->_header_top;
+ for my $filename ( @{ $self->multifasta_files } ) {
+ print { $self->_output_fh } $self->_header_block($filename);
+ }
+ print { $self->_output_fh } $self->_header_bottom;
+ close( $self->_output_fh );
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/Output/DifferenceBetweenSets.pm b/lib/Bio/Roary/Output/DifferenceBetweenSets.pm
new file mode 100644
index 0000000..75aa77c
--- /dev/null
+++ b/lib/Bio/Roary/Output/DifferenceBetweenSets.pm
@@ -0,0 +1,126 @@
+package Bio::Roary::Output::DifferenceBetweenSets;
+
+# ABSTRACT: Given two sets of isolates and a group file, output whats unique in each and whats in common
+
+=head1 SYNOPSIS
+
+Given two sets of isolates and a group file, output whats unique in each and whats in common
+ use Bio::Roary::Output::DifferenceBetweenSets;
+
+ my $obj = Bio::Roary::Output::DifferenceBetweenSets->new(
+ analyse_groups => $analyse_groups,
+ input_filenames_sets =>
+ [
+ ['aaa.faa','bbb.faa'],
+ ['ccc.faa','ddd.faa']
+ ],
+ );
+ $obj->groups_set_one_unique();
+ $obj->groups_set_two_unique();
+ $obj->groups_in_common();
+
+=cut
+
+use Moose;
+use Bio::SeqIO;
+use Bio::Roary::Exceptions;
+use Bio::Roary::AnalyseGroups;
+use Bio::Roary::Output::QueryGroups;
+
+has 'analyse_groups' => ( is => 'ro', isa => 'Bio::Roary::AnalyseGroups', required => 1 );
+has 'input_filenames_sets' => ( is => 'ro', isa => 'ArrayRef[ArrayRef]', required => 1 );
+has 'output_filename_base' => ( is => 'ro', isa => 'Str', default => 'set_difference' );
+
+has '_query_groups_objs' => ( is => 'ro', isa => 'ArrayRef', lazy => 1, builder => '_build__query_groups_objs' );
+
+# TODO: update to handle more than 2 input sets
+
+sub _build__query_groups_objs {
+ my ($self) = @_;
+ my @query_groups_objs;
+ for my $file_name_set ( @{ $self->input_filenames_sets } ) {
+ push(
+ @query_groups_objs,
+ Bio::Roary::Output::QueryGroups->new(
+ analyse_groups => $self->analyse_groups,
+ input_filenames => $file_name_set
+ )
+ );
+ }
+
+ my @all_input_files = (@{ $self->input_filenames_sets->[0] },@{ $self->input_filenames_sets->[1] });
+ push(
+ @query_groups_objs,
+ Bio::Roary::Output::QueryGroups->new(
+ analyse_groups => $self->analyse_groups,
+ input_filenames => \@all_input_files
+ )
+ );
+
+
+ return \@query_groups_objs;
+}
+
+sub _subtract_arrays {
+ my ( $self, $array_1, $array_2 ) = @_;
+ my %array_1 = map { $_ => 1 } @{$array_1};
+ my @difference = grep { not $array_1{$_} } @{$array_2};
+ return \@difference;
+}
+
+sub _groups_unique {
+ my ( $self, $output_filename, $query_group1, $query_group2 ) = @_;
+ my $unique_groups = $self->_subtract_arrays( $query_group2->_groups, $query_group1->_groups );
+ $query_group1->groups_with_external_inputs( $output_filename, $unique_groups );
+}
+
+sub groups_set_one_unique_filename
+{
+ my ($self) = @_;
+ return $self->output_filename_base . '_unique_set_one';
+}
+
+sub groups_set_two_unique_filename
+{
+ my ($self) = @_;
+ return $self->output_filename_base . '_unique_set_two';
+}
+
+sub groups_in_common_filename
+{
+ my ($self) = @_;
+ return $self->output_filename_base . '_common_set';
+}
+
+
+sub groups_set_one_unique {
+ my ($self) = @_;
+ $self->_groups_unique(
+ $self->groups_set_one_unique_filename,
+ $self->_query_groups_objs->[0],
+ $self->_query_groups_objs->[1]
+ );
+}
+
+sub groups_set_two_unique {
+ my ($self) = @_;
+ $self->_groups_unique(
+ $self->groups_set_two_unique_filename,
+ $self->_query_groups_objs->[1],
+ $self->_query_groups_objs->[0]
+ );
+}
+
+sub groups_in_common {
+ my ($self) = @_;
+ my $unique_group_1 = $self->_subtract_arrays( $self->_query_groups_objs->[0]->_groups, $self->_query_groups_objs->[1]->_groups );
+ my $unique_group_2 = $self->_subtract_arrays( $self->_query_groups_objs->[1]->_groups, $self->_query_groups_objs->[0]->_groups );
+ my $common_groups_1 = $self->_subtract_arrays( $unique_group_1,$self->_query_groups_objs->[2]->_groups);
+ my $common_groups_2 = $self->_subtract_arrays( $unique_group_2,$common_groups_1);
+ $self->_query_groups_objs->[2]->groups_with_external_inputs( $self->groups_in_common_filename, $common_groups_2 );
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/Output/EMBLHeaderCommon.pm b/lib/Bio/Roary/Output/EMBLHeaderCommon.pm
new file mode 100644
index 0000000..933a51a
--- /dev/null
+++ b/lib/Bio/Roary/Output/EMBLHeaderCommon.pm
@@ -0,0 +1,41 @@
+package Bio::Roary::Output::EMBLHeaderCommon;
+
+# ABSTRACT: a role containing some common methods for embl header files
+
+=head1 SYNOPSIS
+
+a role containing some common methods for embl header files
+ with 'Bio::Roary::Output::EMBLHeaderCommon';
+
+=cut
+
+use Moose::Role;
+
+sub _header_top {
+ my ($self) = @_;
+ my $header_lines = 'ID Genome standard; DNA; PRO; 1234 BP.' . "\n";
+ $header_lines .= 'XX' . "\n";
+ $header_lines .= 'FH Key Location/Qualifiers' . "\n";
+ $header_lines .= 'FH' . "\n";
+ return $header_lines;
+}
+
+sub _header_bottom {
+ my ($self) = @_;
+ my $header_lines = 'XX' . "\n";
+ $header_lines .= 'SQ Sequence 1234 BP; 789 A; 1717 C; 1693 G; 691 T; 0 other;' . "\n";
+ $header_lines .= '//' . "\n";
+ return $header_lines;
+}
+
+sub _annotation_type {
+ my ( $self, $annotated_group_name ) = @_;
+ my $annotation_type = " feature ";
+ if ( $annotated_group_name =~ /group_/ ) {
+ $annotation_type = " misc_feature ";
+ }
+ return $annotation_type;
+}
+
+
+1;
diff --git a/lib/Bio/Roary/Output/EmblGroups.pm b/lib/Bio/Roary/Output/EmblGroups.pm
new file mode 100644
index 0000000..3612049
--- /dev/null
+++ b/lib/Bio/Roary/Output/EmblGroups.pm
@@ -0,0 +1,246 @@
+package Bio::Roary::Output::EmblGroups;
+
+# ABSTRACT: Create a tab/embl file with the features for drawing pretty pictures
+
+=head1 SYNOPSIS
+
+reate a tab/embl file with the features for drawing pretty pictures
+ use Bio::Roary::Output::EmblGroups;
+
+ my $obj = Bio::Roary::Output::EmblGroups->new(
+ output_filename => 'group_statitics.csv',
+ annotate_groups_obj => $annotate_groups_obj,
+ analyse_groups_obj => $analyse_groups_obj
+ );
+ $obj->create_file;
+
+=cut
+
+use Moose;
+use POSIX;
+use File::Basename;
+use Bio::Roary::Exceptions;
+use Bio::Roary::AnalyseGroups;
+use Bio::Roary::AnnotateGroups;
+with 'Bio::Roary::Output::EMBLHeaderCommon';
+
+has 'annotate_groups_obj' => ( is => 'ro', isa => 'Bio::Roary::AnnotateGroups', required => 1 );
+has 'analyse_groups_obj' => ( is => 'ro', isa => 'Bio::Roary::AnalyseGroups', required => 1 );
+has 'output_filename' => ( is => 'ro', isa => 'Str', default => 'core_accessory.tab' );
+has 'output_header_filename' => ( is => 'ro', isa => 'Str', lazy => 1, builder => '_build_output_header_filename' );
+has 'groups_to_contigs' => ( is => 'ro', isa => 'Maybe[HashRef]' );
+has 'ordering_key' => ( is => 'ro', isa => 'Str', default => 'core_accessory_overall_order' );
+
+has '_output_fh' => ( is => 'ro', lazy => 1, builder => '_build__output_fh' );
+has '_output_header_fh' => ( is => 'ro', lazy => 1, builder => '_build__output_header_fh' );
+has '_sorted_file_names' => ( is => 'ro', isa => 'ArrayRef', lazy => 1, builder => '_build__sorted_file_names' );
+has '_groups_to_files' => ( is => 'ro', isa => 'HashRef', lazy => 1, builder => '_build__groups_to_files' );
+has 'heatmap_lookup_table' => ( is => 'ro', isa => 'ArrayRef', lazy => 1, builder => '_build_heatmap_lookup_table' );
+
+sub _build__output_fh {
+ my ($self) = @_;
+ open( my $fh, '>', $self->output_filename )
+ or Bio::Roary::Exceptions::CouldntWriteToFile->throw( error => "Couldnt write output file:" . $self->output_filename );
+ return $fh;
+}
+
+sub _build__output_header_fh {
+ my ($self) = @_;
+ open( my $fh, '>', $self->output_header_filename )
+ or Bio::Roary::Exceptions::CouldntWriteToFile->throw( error => "Couldnt write output file:" . $self->output_filename );
+ return $fh;
+}
+
+sub _build_output_header_filename {
+ my ($self) = @_;
+ my $base_name = $self->output_filename;
+ $base_name =~ s/\.tab/.header.embl/i;
+ return $base_name;
+}
+
+sub _build__sorted_file_names {
+ my ($self) = @_;
+ my @sorted_file_names = sort( @{ $self->analyse_groups_obj->fasta_files } );
+ return \@sorted_file_names;
+}
+
+sub _build__groups_to_files {
+ my ($self) = @_;
+ my %groups_to_files;
+ for my $group ( @{ $self->annotate_groups_obj->_groups } ) {
+ my $genes = $self->annotate_groups_obj->_groups_to_id_names->{$group};
+ my %filenames;
+ for my $gene_name ( @{$genes} ) {
+ my $filename = $self->analyse_groups_obj->_genes_to_file->{$gene_name};
+ push( @{ $filenames{$filename} }, $gene_name );
+ }
+ $groups_to_files{$group} = \%filenames;
+ }
+ return \%groups_to_files;
+}
+
+sub _block {
+ my ( $self, $group ) = @_;
+ my @taxon_names_array;
+ my $annotated_group_name = $self->annotate_groups_obj->_groups_to_consensus_gene_names->{$group};
+
+ return ''
+ if (
+ !(
+ defined( $self->groups_to_contigs->{$annotated_group_name} )
+ && defined( $self->groups_to_contigs->{$annotated_group_name}->{ $self->ordering_key } )
+ )
+ );
+
+ return ''
+ if ( defined( $self->groups_to_contigs->{$annotated_group_name}->{comment} )
+ && $self->groups_to_contigs->{$annotated_group_name}->{comment} ne '' );
+
+ my $coordindates = $self->groups_to_contigs->{$annotated_group_name}->{ $self->ordering_key };
+
+ for my $filename ( @{ $self->_sorted_file_names } ) {
+ my $group_to_file_genes = $self->_groups_to_files->{$group}->{$filename};
+
+ if ( defined($group_to_file_genes) && @{$group_to_file_genes} > 0 ) {
+ my $filename_cpy = basename($filename);
+ $filename_cpy =~ s!\.gff\.proteome\.faa!!;
+ push( @taxon_names_array, $filename_cpy );
+ next;
+ }
+ }
+
+ my $colour = $self->_get_heat_map_colour( \@taxon_names_array, $self->annotate_groups_obj->_number_of_files );
+
+ my $taxon_names = join( " ", @taxon_names_array );
+
+ my $tab_file_entry = "FT variation $coordindates\n";
+ $tab_file_entry .= "FT /colour=$colour\n";
+ $tab_file_entry .= "FT /gene=$annotated_group_name\n";
+ $tab_file_entry .= "FT /taxa=\"$taxon_names\"\n";
+
+ return $tab_file_entry;
+}
+
+sub _get_heat_map_colour {
+ my ( $self, $taxon_names, $number_of_files ) = @_;
+ return $self->heatmap_lookup_table->[0] if ( @{$taxon_names} == 1 );
+ my $number_of_colours = @{ $self->heatmap_lookup_table };
+ return $self->heatmap_lookup_table->[ $number_of_colours - 1 ] if ( @{$taxon_names} == $number_of_files );
+
+ my $block_size = $number_of_files / @{ $self->heatmap_lookup_table };
+ my $colour_index = ceil( @{$taxon_names} / $block_size ) - 1;
+ return $self->heatmap_lookup_table->[$colour_index];
+}
+
+sub _build_heatmap_lookup_table {
+ my ($self) = @_;
+ return [
+ 4, # blue (RGB values: 0 0 255)
+ 5, # cyan (RGB values: 0 255 255)
+ 9, # light sky blue (RGB values: 135 206 250)
+ 8, # pale green (RGB values: 152 251 152)
+ 3, # green (RGB values: 0 255 0)
+ 7, # yellow (RGB values: 255 255 0)
+ 10, # orange (RGB values: 255 165 0)
+ 16, # light red (RGB values: 255 127 127)
+ 15, # mid red: (RGB values: 255 63 63)
+ 2, # red (RGB values: 255 0 0)
+ ];
+}
+
+sub _block_colour {
+ my ( $self, $accessory_label ) = @_;
+ my $colour = 2;
+ return $colour unless ( defined($accessory_label) );
+
+ $colour += $accessory_label % 6;
+ return $colour;
+}
+
+sub _header_block {
+ my ( $self, $group ) = @_;
+ my $annotated_group_name = $self->annotate_groups_obj->_groups_to_consensus_gene_names->{$group};
+ my $colour = 1;
+
+ return ''
+ if (
+ !(
+ defined( $self->groups_to_contigs->{$annotated_group_name} )
+ && defined( $self->groups_to_contigs->{$annotated_group_name}->{ $self->ordering_key } )
+ )
+ );
+ return ''
+ if ( defined( $self->groups_to_contigs->{$annotated_group_name}->{comment} )
+ && $self->groups_to_contigs->{$annotated_group_name}->{comment} ne '' );
+ my $coordindates = $self->groups_to_contigs->{$annotated_group_name}->{ $self->ordering_key };
+ my $annotation_type = $self->_annotation_type($annotated_group_name);
+
+ $colour = $self->_block_colour( $self->groups_to_contigs->{$annotated_group_name}->{accessory_label} );
+
+ my $tab_file_entry = "FT$annotation_type$coordindates\n";
+ $tab_file_entry .= "FT /label=$annotated_group_name\n";
+ $tab_file_entry .= "FT /locus_tag=$annotated_group_name\n";
+ $tab_file_entry .= "FT /colour=$colour\n";
+
+ return $tab_file_entry;
+}
+
+sub _fragment_blocks {
+ my ( $self, $fh ) = @_;
+ my %fragment_numbers;
+ for my $group ( @{ $self->annotate_groups_obj->_groups } ) {
+ my $annotated_group_name = $self->annotate_groups_obj->_groups_to_consensus_gene_names->{$group};
+
+ next unless ( defined( $self->groups_to_contigs->{$annotated_group_name}->{accessory_label} ) );
+ next unless ( defined( $self->groups_to_contigs->{$annotated_group_name}->{ $self->ordering_key } ) );
+ next if ( $self->groups_to_contigs->{$annotated_group_name}->{ $self->ordering_key } eq '' );
+ push(
+ @{ $fragment_numbers{ $self->groups_to_contigs->{$annotated_group_name}->{accessory_label} } },
+ $self->groups_to_contigs->{$annotated_group_name}->{ $self->ordering_key }
+ );
+ }
+
+ for my $accessory_label ( keys %fragment_numbers ) {
+ next unless ( defined( $fragment_numbers{$accessory_label} ) );
+ my @sorted_fragment = sort { $a <=> $b } @{ $fragment_numbers{$accessory_label} };
+ my $tab_file_entry = '';
+ if ( @sorted_fragment > 1 ) {
+ my $min = $sorted_fragment[0];
+ my $max = $sorted_fragment[-1];
+
+ next if ( !defined($min) || !defined($max) || $min eq '' || $max eq '' );
+ $tab_file_entry = "FT feature $min" . '..' . "$max\n";
+ }
+ elsif ( @sorted_fragment == 1 ) {
+ my $min = $sorted_fragment[0];
+ next if ( !defined($min) || $min eq '' );
+ $tab_file_entry = "FT feature $min\n";
+ }
+ else {
+ next;
+ }
+ $tab_file_entry .= "FT /colour=" . $self->_block_colour($accessory_label) . "\n";
+
+ print {$fh} $tab_file_entry;
+ }
+
+}
+
+sub create_files {
+ my ($self) = @_;
+
+ print { $self->_output_header_fh } $self->_header_top();
+ for my $group ( @{ $self->annotate_groups_obj->_groups } ) {
+ print { $self->_output_fh } $self->_block($group);
+ print { $self->_output_header_fh } $self->_header_block($group);
+ }
+ $self->_fragment_blocks( $self->_output_header_fh );
+ print { $self->_output_header_fh } $self->_header_bottom();
+ close( $self->_output_header_fh );
+ close( $self->_output_fh );
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/Output/GroupMultifasta.pm b/lib/Bio/Roary/Output/GroupMultifasta.pm
new file mode 100644
index 0000000..97204fe
--- /dev/null
+++ b/lib/Bio/Roary/Output/GroupMultifasta.pm
@@ -0,0 +1,69 @@
+package Bio::Roary::Output::GroupMultifasta;
+
+# ABSTRACT: Take in a group and create a multifasta file
+
+=head1 SYNOPSIS
+
+Take in a group and create a multifasta file
+ use Bio::Roary::Output::GroupMultifasta;
+
+ my $obj = Bio::Roary::Output::GroupMultifasta->new(
+ group_name => 'aaa',
+ analyse_groups => $analyse_groups,
+ output_filename_base => 'abc'
+ );
+ $obj->create_file();
+
+=cut
+
+use Moose;
+use Bio::SeqIO;
+use Bio::Roary::Exceptions;
+use Bio::Roary::AnalyseGroups;
+
+has 'group_name' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'analyse_groups' => ( is => 'ro', isa => 'Bio::Roary::AnalyseGroups', required => 1 );
+has 'output_filename_base' => ( is => 'ro', isa => 'Str', default => 'output_groups' );
+has '_genes' => ( is => 'ro', isa => 'ArrayRef', lazy => 1, builder => '_build__genes' );
+has '_output_seq_io' => ( is => 'ro', lazy => 1, builder => '_build__output_seq_io' );
+
+sub _build__output_seq_io {
+ my ($self) = @_;
+ my $output_name = $self->output_filename_base . '_' . $self->group_name;
+ $output_name =~ s!\W!_!g;
+ $output_name .= '.fa';
+ return Bio::SeqIO->new( -file => ">" . $output_name, -format => 'Fasta' );
+}
+
+sub _build__genes {
+ my ($self) = @_;
+ return $self->analyse_groups->_groups_to_genes->{ $self->group_name };
+}
+
+sub _lookup_sequence {
+ my ( $self, $gene, $filename ) = @_;
+ return undef if(! defined($filename));
+ my $fasta_obj = Bio::SeqIO->new( -file => $filename, -format => 'Fasta' );
+ while ( my $seq = $fasta_obj->next_seq() ) {
+ next unless ( $seq->display_id eq $gene );
+ return $seq;
+ }
+ return undef;
+}
+
+sub create_file {
+ my ($self) = @_;
+ for my $gene ( @{ $self->_genes } ) {
+ my $seq = $self->_lookup_sequence( $gene, $self->analyse_groups->_genes_to_file->{$gene} );
+ next unless ( defined($seq) );
+ $self->_output_seq_io->write_seq($seq);
+ }
+
+ 1;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
+
diff --git a/lib/Bio/Roary/Output/GroupsMultifastaNucleotide.pm b/lib/Bio/Roary/Output/GroupsMultifastaNucleotide.pm
new file mode 100644
index 0000000..0433c58
--- /dev/null
+++ b/lib/Bio/Roary/Output/GroupsMultifastaNucleotide.pm
@@ -0,0 +1,166 @@
+package Bio::Roary::Output::GroupsMultifastaNucleotide;
+
+# ABSTRACT: Take in a GFF files and a groups file and output one multifasta file per group with nucleotide sequences.
+
+=head1 SYNOPSIS
+
+Take in a GFF files and a groups file and output one multifasta file per group with nucleotide sequences.
+ use Bio::Roary::Output::GroupsMultifastas;
+
+ my $obj = Bio::Roary::Output::GroupsMultifastasNucleotide->new(
+ group_names => ['aaa','bbb'],
+ );
+ $obj->populate_files();
+
+=cut
+
+use Moose;
+use Bio::SeqIO;
+use File::Path qw(make_path);
+use File::Basename;
+use Bio::Roary::Exceptions;
+use Bio::Roary::AnalyseGroups;
+use Bio::Tools::GFF;
+with 'Bio::Roary::BedFromGFFRole';
+
+has 'gff_file' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'group_names' => ( is => 'ro', isa => 'ArrayRef', required => 0 );
+has 'output_directory' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'pan_reference_groups_seen' => ( is => 'rw', isa => 'HashRef', required => 1 );
+has 'number_of_gff_files' => ( is => 'ro', isa => 'Int', required => 1 );
+has 'pan_reference_filename' => ( is => 'ro', isa => 'Str',default => 'pan_genome_reference.fa' );
+has 'dont_delete_files' => ( is => 'ro', isa => 'Bool',default => 0 );
+has 'core_definition' => ( is => 'ro', isa => 'Num', default => 1.0 );
+
+has 'annotate_groups' => ( is => 'ro', isa => 'Bio::Roary::AnnotateGroups', required => 1 );
+has 'output_multifasta_files' => ( is => 'ro', isa => 'Bool', default => 0 );
+
+has 'fasta_file' => ( is => 'ro', isa => 'Str', lazy => 1, builder => '_build_fasta_file' );
+has '_input_seqio' => ( is => 'ro', isa => 'Bio::SeqIO', lazy => 1, builder => '_build__input_seqio' );
+
+has 'output_filename' => ( is => 'ro', isa => 'Str', lazy => 1, builder => '_build_output_filename' );
+
+sub _build_output_filename
+{
+ my ($self) = @_;
+ my ( $filename, $directories, $suffix ) = fileparse($self->gff_file);
+ return join('/',($self->output_directory, $filename.'.tmp_nuc_sequences.fa' ));
+}
+
+sub _build__input_seqio {
+ my ($self) = @_;
+ return Bio::SeqIO->new( -file => $self->fasta_file, -format => 'Fasta' );
+}
+
+sub _bed_output_filename {
+ my ($self) = @_;
+ return join( '.', ( $self->output_filename, 'intermediate.bed' ) );
+}
+
+sub populate_files {
+ my ($self) = @_;
+ while ( my $input_seq = $self->_input_seqio->next_seq() )
+ {
+ if ( $self->annotate_groups->_ids_to_groups->{$input_seq->display_id} )
+ {
+ my $current_group = $self->annotate_groups->_ids_to_groups->{$input_seq->display_id};
+ my $gene_name = $self->annotate_groups->_groups_to_consensus_gene_names->{$current_group};
+
+ if(! defined($self->pan_reference_groups_seen->{$current_group}))
+ {
+ my $pan_output_seq = $self->_pan_genome_reference_io_obj($current_group);
+ $pan_output_seq->write_seq(Bio::Seq->new( -display_id => $input_seq->display_id, -desc => ($gene_name ? $gene_name : $current_group), -seq => $input_seq->seq ) );
+ $self->pan_reference_groups_seen->{$current_group} = 1;
+ }
+
+ my $number_of_genes = @{$self->annotate_groups->_groups_to_id_names->{$current_group}};
+ # Theres no need to align noncore files
+ next if($self->dont_delete_files == 0 && $number_of_genes < ($self->core_definition * $self->number_of_gff_files ));
+
+ my $output_seq = $self->_group_seq_io_obj($current_group,$number_of_genes);
+ $output_seq->write_seq($input_seq);
+ }
+ }
+
+ unlink($self->fasta_file);
+ 1;
+}
+
+sub _group_file_name
+{
+ my ($self,$group_name,$num_group_genes) = @_;
+ my $annotated_group_name = $self->annotate_groups->_groups_to_consensus_gene_names->{$group_name};
+ $annotated_group_name =~ s!\W!_!gi;
+ my $filename = $annotated_group_name.'.fa';
+ my $group_file_name = join('/',($self->output_directory, $filename ));
+ return $group_file_name;
+}
+
+
+sub _pan_genome_reference_io_obj
+{
+ my ($self) = @_;
+ return Bio::SeqIO->new( -file => ">>".$self->pan_reference_filename, -format => 'Fasta' );
+}
+
+
+sub _group_seq_io_obj
+{
+ my ($self,$group_name,$num_group_genes) = @_;
+ my $filename = $self->_group_file_name($group_name,$num_group_genes);
+ return Bio::SeqIO->new( -file => ">>".$filename, -format => 'Fasta' );
+}
+
+
+sub _extracted_nucleotide_fasta_file_from_bed_filename {
+ my ($self) = @_;
+ return join( '.', ( $self->output_filename, 'intermediate.extracted.fa' ) );
+}
+
+
+
+sub _create_nucleotide_fasta_file_from_gff {
+ my ($self) = @_;
+ my $cmd =
+ 'sed -n \'/##FASTA/,//p\' '
+ . $self->gff_file
+ . ' | grep -v \'##FASTA\' > '
+ . $self->_nucleotide_fasta_file_from_gff_filename;
+ system($cmd);
+}
+
+sub _nucleotide_fasta_file_from_gff_filename {
+ my ($self) = @_;
+ return join( '.', ( $self->output_filename, 'intermediate.fa' ) );
+}
+
+sub _extract_nucleotide_regions {
+ my ($self) = @_;
+
+ $self->_create_nucleotide_fasta_file_from_gff;
+ $self->_create_bed_file_from_gff;
+
+ my $cmd =
+ 'bedtools getfasta -s -fi '
+ . $self->_nucleotide_fasta_file_from_gff_filename
+ . ' -bed '
+ . $self->_bed_output_filename . ' -fo '
+ . $self->_extracted_nucleotide_fasta_file_from_bed_filename
+ . ' -name > /dev/null 2>&1';
+ system($cmd);
+ unlink( $self->_nucleotide_fasta_file_from_gff_filename );
+ unlink( $self->_bed_output_filename );
+ unlink( $self->_nucleotide_fasta_file_from_gff_filename . '.fai' );
+ return $self->_extracted_nucleotide_fasta_file_from_bed_filename;
+}
+
+sub _build_fasta_file {
+ my ($self) = @_;
+ return $self->_extract_nucleotide_regions;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
+
diff --git a/lib/Bio/Roary/Output/GroupsMultifastaProtein.pm b/lib/Bio/Roary/Output/GroupsMultifastaProtein.pm
new file mode 100644
index 0000000..3b9df70
--- /dev/null
+++ b/lib/Bio/Roary/Output/GroupsMultifastaProtein.pm
@@ -0,0 +1,68 @@
+package Bio::Roary::Output::GroupsMultifastaProtein;
+
+# ABSTRACT: Take a multifasta nucleotide file and output it as proteins.
+
+=head1 SYNOPSIS
+
+Take a multifasta nucleotide file and output it as proteins.
+ use Bio::Roary::Output::GroupsMultifastaProtein;
+
+ my $obj = Bio::Roary::Output::GroupsMultifastaProtein->new(
+ nucleotide_fasta_file => 'example.fa'
+ );
+ $obj->convert_nucleotide_to_protein();
+
+=cut
+
+use Moose;
+use Bio::SeqIO;
+use File::Path qw(make_path);
+use File::Basename;
+use Bio::Roary::Exceptions;
+use Bio::Roary::AnalyseGroups;
+
+has 'nucleotide_fasta_file' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'output_filename' => ( is => 'ro', isa => 'Str', lazy => 1, builder => '_build_output_filename' );
+has '_suffix' => ( is => 'ro', isa => 'Str', default => '.faa' );
+has 'translation_table' => ( is => 'rw', isa => 'Int', default => 11 );
+
+sub _build_output_filename
+{
+ my ($self) = @_;
+ my ( $filename, $directories, $suffix ) = fileparse($self->nucleotide_fasta_file, qr/\.[^.]*/);
+
+ return join('',($directories, $filename.$self->_suffix));
+}
+
+# Read all the sequences for a gene into memory to sort them - very small files so shouldnt be a problem
+sub _fastatranslate
+{
+ my ($self) = @_;
+ my $input_fasta_file_obj = Bio::SeqIO->new(-file => $self->nucleotide_fasta_file, -format => 'Fasta' );
+ my $output_protein_file_obj = Bio::SeqIO->new(-file =>">".$self->output_filename, -format => 'Fasta', -alphabet => 'protein' );
+
+ my %protein_sequence_objs;
+ while (my $seq = $input_fasta_file_obj->next_seq){
+ $protein_sequence_objs{$seq->display_id} = $seq->translate(-codontable_id => $self->translation_table );
+ }
+
+ for my $sequence_name ( sort keys %protein_sequence_objs)
+ {
+ $output_protein_file_obj->write_seq($protein_sequence_objs{$sequence_name});
+ }
+
+ return 1;
+}
+
+sub convert_nucleotide_to_protein
+{
+ my ($self) = @_;
+ $self->_fastatranslate();
+ 1;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
+
diff --git a/lib/Bio/Roary/Output/GroupsMultifastas.pm b/lib/Bio/Roary/Output/GroupsMultifastas.pm
new file mode 100644
index 0000000..4881806
--- /dev/null
+++ b/lib/Bio/Roary/Output/GroupsMultifastas.pm
@@ -0,0 +1,46 @@
+package Bio::Roary::Output::GroupsMultifastas;
+
+# ABSTRACT: Take in a list of groups and create multifastas files for each group
+
+=head1 SYNOPSIS
+
+Take in a list of groups and create multifastas files for each group
+ use Bio::Roary::Output::GroupsMultifastas;
+
+ my $obj = Bio::Roary::Output::GroupsMultifastas->new(
+ group_names => ['aaa','bbb'],
+ analyse_groups => $analyse_groups
+ );
+ $obj->create_files();
+
+=cut
+
+use Moose;
+use Bio::Roary::Exceptions;
+use Bio::Roary::AnalyseGroups;
+use Bio::Roary::Output::GroupMultifasta;
+
+has 'group_names' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'analyse_groups' => ( is => 'ro', isa => 'Bio::Roary::AnalyseGroups', required => 1 );
+has 'output_filename_base' => ( is => 'ro', isa => 'Str', default => 'output_groups' );
+
+sub create_files {
+ my ($self) = @_;
+ for my $group_name ( @{ $self->group_names } ) {
+ # Check the group name exists
+ next unless($self->analyse_groups->_groups_to_genes->{$group_name});
+ my $group_multifasta = Bio::Roary::Output::GroupMultifasta->new(
+ group_name => $group_name,
+ analyse_groups => $self->analyse_groups,
+ output_filename_base => $self->output_filename_base
+ );
+ $group_multifasta->create_file;
+ }
+ 1;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
+
diff --git a/lib/Bio/Roary/Output/GroupsMultifastasNucleotide.pm b/lib/Bio/Roary/Output/GroupsMultifastasNucleotide.pm
new file mode 100644
index 0000000..b466905
--- /dev/null
+++ b/lib/Bio/Roary/Output/GroupsMultifastasNucleotide.pm
@@ -0,0 +1,86 @@
+
+package Bio::Roary::Output::GroupsMultifastasNucleotide;
+
+# ABSTRACT: Take in a set of GFF files and a groups file and output one multifasta file per group with nucleotide sequences.
+
+=head1 SYNOPSIS
+
+Take in a set of GFF files and a groups file and output one multifasta file per group with nucleotide sequences.
+ use Bio::Roary::Output::GroupsMultifastasNucleotide;
+
+ my $obj = Bio::Roary::Output::GroupsMultifastasNucleotide->new(
+ group_names => ['aaa','bbb'],
+ analyse_groups => $analyse_groups
+ );
+ $obj->create_files();
+
+=cut
+
+use Moose;
+use File::Path qw(make_path);
+use Bio::Roary::Exceptions;
+use Bio::Roary::AnalyseGroups;
+use Bio::Roary::Output::GroupsMultifastaNucleotide;
+
+has 'gff_files' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'group_names' => ( is => 'ro', isa => 'ArrayRef', required => 0 );
+has 'annotate_groups' => ( is => 'ro', isa => 'Bio::Roary::AnnotateGroups', required => 1 );
+has 'output_multifasta_files' => ( is => 'ro', isa => 'Bool', default => 0 );
+has 'core_definition' => ( is => 'ro', isa => 'Num', default => 1.0 );
+has 'dont_delete_files' => ( is => 'ro', isa => 'Bool', default => 0 );
+has 'output_directory' => ( is => 'ro', isa => 'Str', lazy => 1, builder => '_build_output_directory');
+has '_number_of_groups' => ( is => 'rw', isa => 'Num', lazy => 1, builder => '_build__number_of_groups' );
+has 'group_limit' => ( is => 'rw', isa => 'Num', default => 50000 );
+
+sub _build_output_directory
+{
+ my ($self) = @_;
+ my $output_directory = 'pan_genome_sequences';
+ return $output_directory;
+}
+
+sub _build__number_of_groups {
+ my $self = shift;
+
+ return $self->annotate_groups->_group_counter;
+}
+
+sub create_files {
+ my ($self) = @_;
+
+ my $num_groups = $self->_number_of_groups;
+ my $limit = $self->group_limit;
+ if ( $num_groups > $limit ){
+ print STDERR "Number of clusters ($num_groups) exceeds limit ($limit). Multifastas not created. Please check the spreadsheet for contamination from different species or increase the --group_limit parameter.\n";
+ return 0;
+ }
+
+ make_path($self->output_directory);
+ unlink('pan_genome_reference.fa');
+
+ my $number_of_gff_files = @{$self->gff_files};
+ my %pan_reference_groups_seen;
+ # if its output_multifasta_files == false then you want to create the core genome and delete all intermediate multifasta files
+ for my $gff_file ( @{ $self->gff_files } )
+ {
+ my $gff_multifasta = Bio::Roary::Output::GroupsMultifastaNucleotide->new(
+ gff_file => $gff_file,
+ group_names => $self->group_names,
+ output_directory => $self->output_directory,
+ annotate_groups => $self->annotate_groups,
+ output_multifasta_files => $self->output_multifasta_files,
+ pan_reference_groups_seen => \%pan_reference_groups_seen,
+ core_definition => $self->core_definition,
+ dont_delete_files => $self->dont_delete_files,
+ number_of_gff_files => $number_of_gff_files
+ );
+ $gff_multifasta->populate_files;
+ }
+ 1;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
+
diff --git a/lib/Bio/Roary/Output/NumberOfGroups.pm b/lib/Bio/Roary/Output/NumberOfGroups.pm
new file mode 100644
index 0000000..0dd9370
--- /dev/null
+++ b/lib/Bio/Roary/Output/NumberOfGroups.pm
@@ -0,0 +1,121 @@
+package Bio::Roary::Output::NumberOfGroups;
+
+# ABSTRACT: Create raw output files of group counts for turning into plots
+
+=head1 SYNOPSIS
+
+# ABSTRACT: Create raw output files of group counts for turning into plots
+use Bio::Roary::Output::NumberOfGroups;
+
+my $obj = Bio::Roary::Output::NumberOfGroups->new(
+ group_statistics_obj => $group_stats
+ );
+$obj->create_files();
+
+=cut
+
+use Moose;
+use List::Util qw(shuffle);
+use Bio::Roary::AnnotateGroups;
+use Bio::Roary::GroupStatistics;
+
+has 'group_statistics_obj' => ( is => 'ro', isa => 'Bio::Roary::GroupStatistics', required => 1 );
+has 'number_of_iterations' => ( is => 'ro', isa => 'Int', default => 10);
+has 'groups_to_contigs' => ( is => 'ro', isa => 'Maybe[HashRef]' );
+has 'annotate_groups_obj' => ( is => 'ro', isa => 'Bio::Roary::AnnotateGroups', required => 1 );
+has 'core_definition' => ( is => 'ro', isa => 'Num', default => 1.0 );
+
+has 'output_raw_filename_conserved_genes' => ( is => 'ro', isa => 'Str', default => 'number_of_conserved_genes.Rtab' );
+has 'output_raw_filename_unique_genes' => ( is => 'ro', isa => 'Str', default => 'number_of_unique_genes.Rtab' );
+has 'output_raw_filename_total_genes' => ( is => 'ro', isa => 'Str', default => 'number_of_genes_in_pan_genome.Rtab' );
+has 'output_raw_filename_new_genes' => ( is => 'ro', isa => 'Str', default => 'number_of_new_genes.Rtab' );
+has '_conserved_genes' => ( is => 'ro', isa => 'ArrayRef', default => sub { [] } );
+has '_unique_genes' => ( is => 'ro', isa => 'ArrayRef', default => sub { [] } );
+has '_total_genes' => ( is => 'ro', isa => 'ArrayRef', default => sub { [] } );
+has '_new_genes' => ( is => 'ro', isa => 'ArrayRef', default => sub { [] } );
+
+sub create_output_files {
+ my ($self) = @_;
+
+ for ( my $i = 0 ; $i < $self->number_of_iterations ; $i++ ) {
+ $self->_single_iteration_gene_expansion;
+ }
+
+ $self->_create_raw_output_file( $self->output_raw_filename_conserved_genes, $self->_conserved_genes );
+ $self->_create_raw_output_file( $self->output_raw_filename_unique_genes, $self->_unique_genes );
+ $self->_create_raw_output_file( $self->output_raw_filename_total_genes, $self->_total_genes );
+ $self->_create_raw_output_file( $self->output_raw_filename_new_genes, $self->_new_genes );
+ return 1;
+}
+
+sub _create_raw_output_file {
+ my ( $self, $filename, $output_data ) = @_;
+ open( my $fh, '>', $filename );
+ for my $iterations ( @{$output_data} ) {
+ print {$fh} join( "\t", @{$iterations} );
+ print {$fh} "\n";
+ }
+ close($fh);
+}
+
+sub _shuffle_input_files {
+ my ($self) = @_;
+ my @shuffled_input_files = shuffle( @{ $self->group_statistics_obj->_sorted_file_names } );
+ return \@shuffled_input_files;
+}
+
+sub _single_iteration_gene_expansion {
+ my ($self) = @_;
+ my %existing_groups;
+ my @conserved_genes_added_per_file;
+ my @unique_genes_added_per_file;
+ my @total_genes_added_per_file;
+ my @new_genes_added_per_file;
+
+ my $shuffled_input_files = $self->_shuffle_input_files();
+
+ my $files_counter = 1;
+ for my $input_file ( @{$shuffled_input_files} ) {
+ my $unique_groups_counter = 0;
+ my $total_groups_counter = 0;
+ my $new_group_counter = 0;
+ my $conserved_groups_counter = 0;
+ my $new_groups = $self->group_statistics_obj->_files_to_groups->{$input_file};
+
+ for my $group ( @{$new_groups} ) {
+ if ( !defined( $existing_groups{$group} ) ) {
+ $new_group_counter++;
+ }
+ $existing_groups{$group}++;
+ }
+
+ for my $group ( keys %existing_groups ) {
+ if ( $existing_groups{$group} >= ($files_counter*$self->core_definition) ) {
+ $conserved_groups_counter++;
+ }
+
+ if ( $existing_groups{$group} == 1 ) {
+ $unique_groups_counter++;
+ }
+ $total_groups_counter++;
+ }
+
+ push( @conserved_genes_added_per_file, $conserved_groups_counter );
+ push( @unique_genes_added_per_file, $unique_groups_counter );
+ push( @total_genes_added_per_file, $total_groups_counter );
+ push( @new_genes_added_per_file, $new_group_counter );
+ $files_counter++;
+ }
+ push( @{ $self->_conserved_genes }, \@conserved_genes_added_per_file );
+ push( @{ $self->_unique_genes }, \@unique_genes_added_per_file );
+ push( @{ $self->_total_genes }, \@total_genes_added_per_file );
+ push( @{ $self->_new_genes }, \@new_genes_added_per_file );
+
+ return;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
+
diff --git a/lib/Bio/Roary/Output/QueryGroups.pm b/lib/Bio/Roary/Output/QueryGroups.pm
new file mode 100644
index 0000000..312973d
--- /dev/null
+++ b/lib/Bio/Roary/Output/QueryGroups.pm
@@ -0,0 +1,139 @@
+package Bio::Roary::Output::QueryGroups;
+
+# ABSTRACT: Output the groups of the union of a set of input isolates
+
+=head1 SYNOPSIS
+
+Output the groups of the union of a set of input isolates
+ use Bio::Roary::Output::QueryGroups;
+
+ my $obj = Bio::Roary::Output::QueryGroups->new(
+ analyse_groups => $analyse_groups
+ );
+ $obj->groups_union();
+ $obj->groups_intersection();
+ $obj->groups_complement();
+
+=cut
+
+use Moose;
+use Bio::SeqIO;
+use Bio::Roary::Exceptions;
+use Bio::Roary::AnalyseGroups;
+use POSIX;
+
+has 'analyse_groups' => ( is => 'ro', isa => 'Bio::Roary::AnalyseGroups', required => 1 );
+has 'input_filenames' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'output_union_filename' => ( is => 'ro', isa => 'Str', default => 'union_of_groups.gg' );
+has 'output_intersection_filename' => ( is => 'ro', isa => 'Str', default => 'intersection_of_groups.gg' );
+has 'output_complement_filename' => ( is => 'ro', isa => 'Str', default => 'complement_of_groups.gg' );
+has 'core_definition' => ( is => 'ro', isa => 'Num', default => 1.0 );
+
+has '_groups_freq' => ( is => 'ro', isa => 'HashRef', lazy => 1, builder => '_build__groups_freq' );
+has '_groups_intersection' => ( is => 'ro', isa => 'ArrayRef', lazy => 1, builder => '_build__groups_intersection' );
+has '_groups_complement' => ( is => 'ro', isa => 'ArrayRef', lazy => 1, builder => '_build__groups_complement' );
+has '_groups' => ( is => 'ro', isa => 'ArrayRef', lazy => 1, builder => '_build__groups' );
+has '_number_of_isolates' => ( is => 'ro', isa => 'Int', lazy => 1, builder => '_builder__number_of_isolates' );
+has '_min_no_isolates_for_core' => ( is => 'rw', isa => 'Int', lazy_build => 1 );
+
+sub _build__min_no_isolates_for_core {
+ my ( $self ) = @_;
+ my $threshold = ceil( $self->_number_of_isolates * $self->core_definition );
+
+ return $threshold;
+}
+
+sub _builder__number_of_isolates {
+ my ($self) = @_;
+ return @{ $self->input_filenames };
+}
+
+sub _build__groups_freq {
+ my ($self) = @_;
+ my %groups_freq;
+
+ for my $filename ( @{ $self->input_filenames } ) {
+ my $genes = $self->analyse_groups->_files_to_genes->{$filename};
+
+ my %file_groups_seen;
+ for my $gene ( @{$genes} ) {
+ next if(!defined($gene));
+ next if(!defined($self->analyse_groups->_genes_to_groups->{$gene}));
+ next if(defined($file_groups_seen{$self->analyse_groups->_genes_to_groups->{$gene}}));
+
+ push(@{$groups_freq{ $self->analyse_groups->_genes_to_groups->{$gene} }}, $gene);
+ $file_groups_seen{$self->analyse_groups->_genes_to_groups->{$gene}} = 1;
+ }
+ }
+
+ return \%groups_freq;
+}
+
+sub _build__groups {
+ my ($self) = @_;
+ my %groups_freq = %{ $self->_groups_freq };
+ my @groups = sort { @{$groups_freq{$b}} <=> @{$groups_freq{$a}} } keys %groups_freq;
+ return \@groups;
+}
+
+sub _build__groups_intersection {
+ my ($self) = @_;
+ my @groups_intersection;
+
+ for my $group ( @{$self->_groups} ) {
+ if ( scalar @{$self->_groups_freq->{$group}} >= $self->_min_no_isolates_for_core ) {
+ push( @groups_intersection, $group );
+ }
+ }
+ return \@groups_intersection;
+}
+
+sub _build__groups_complement {
+ my ($self) = @_;
+ my %groups_intersection = map { $_ => 1 } @{ $self->_groups_intersection };
+ my @complement = grep { not $groups_intersection{$_} } @{ $self->_groups };
+ return \@complement;
+}
+
+sub _print_out_groups {
+ my ( $self, $filename, $groups ) = @_;
+ open( my $fh, '>', $filename )
+ or Bio::Roary::Exceptions::CouldntWriteToFile->throw( error => 'Couldnt write to file: ' . $filename );
+
+ my %groups_freq = %{ $self->_groups_freq };
+ my @sorted_groups = sort { @{$groups_freq{$b}} <=> @{$groups_freq{$a}} } @{$groups};
+
+ for my $group ( @sorted_groups ) {
+ print {$fh} $group.': '.join("\t",@{$self->_groups_freq->{$group}}) . "\n";
+ }
+ close($fh);
+ return $self;
+}
+
+sub groups_complement {
+ my ($self) = @_;
+ $self->_print_out_groups( $self->output_complement_filename, $self->_groups_complement );
+}
+
+sub groups_intersection {
+ my ($self) = @_;
+ $self->_print_out_groups( $self->output_intersection_filename, $self->_groups_intersection );
+}
+
+sub groups_union {
+ my ($self) = @_;
+ $self->_print_out_groups( $self->output_union_filename, $self->_groups );
+}
+
+sub groups_with_external_inputs
+{
+ my ($self, $output_filename,$groups) = @_;
+ $self->_print_out_groups( $output_filename, $groups );
+
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
+
diff --git a/lib/Bio/Roary/ParallelAllAgainstAllBlast.pm b/lib/Bio/Roary/ParallelAllAgainstAllBlast.pm
new file mode 100644
index 0000000..17474b0
--- /dev/null
+++ b/lib/Bio/Roary/ParallelAllAgainstAllBlast.pm
@@ -0,0 +1,143 @@
+package Bio::Roary::ParallelAllAgainstAllBlast;
+
+# ABSTRACT: Run all against all blast in parallel
+
+=head1 SYNOPSIS
+
+Run blastp in parallel over a FASTA file of proteins
+ use Bio::Roary::ParallelAllAgainstAllBlast;
+
+ my $obj = Bio::Roary::ParallelAllAgainstAllBlast->new(
+ fasta_file => 'abc.fa',
+ );
+ $obj->run();
+
+=cut
+
+use Moose;
+use Bio::Roary::Exceptions;
+use Bio::Roary::ChunkFastaFile;
+use Bio::Roary::External::Makeblastdb;
+use Bio::Roary::External::Blastp;
+use Cwd;
+use File::Temp;
+use File::Basename;
+with 'Bio::Roary::JobRunner::Role';
+
+has 'fasta_file' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'blast_results_file_name' => ( is => 'ro', isa => 'Str', lazy => 1, builder => '_build_blast_results_file_name' );
+has 'makeblastdb_exec' => ( is => 'ro', isa => 'Str', default => 'makeblastdb' );
+has 'blastp_exec' => ( is => 'ro', isa => 'Str', default => 'blastp' );
+has 'segmasker_exec' => ( is => 'ro', isa => 'Str', default => 'segmasker' );
+has 'perc_identity' => ( is => 'ro', isa => 'Num', default => 98 );
+has '_chunk_fasta_file_obj' => ( is => 'ro', isa => 'Bio::Roary::ChunkFastaFile', lazy => 1, builder => '_build__chunk_fasta_file_obj' );
+has '_sequence_file_names' => ( is => 'ro', isa => 'ArrayRef', lazy => 1, builder => '_build__sequence_file_names' );
+has '_makeblastdb_obj' => ( is => 'ro', isa => 'Bio::Roary::External::Makeblastdb', lazy => 1, builder => '_build__makeblastdb_obj' );
+has '_blast_database' => ( is => 'ro', isa => 'Str', lazy => 1, builder => '_build__blast_database' );
+has 'cpus' => ( is => 'ro', isa => 'Int', default => 1 );
+
+has '_working_directory' =>
+ ( is => 'ro', isa => 'File::Temp::Dir', default => sub { File::Temp->newdir( DIR => getcwd, CLEANUP => 1 ); } );
+has '_working_directory_name' => ( is => 'ro', isa => 'Str', lazy => 1, builder => '_build__working_directory_name' );
+
+has 'memory_in_mb' => ( is => 'ro', isa => 'Int', lazy => 1, builder => '_build_memory_in_mb' );
+
+
+sub BUILD {
+ my ($self) = @_;
+ $self->_makeblastdb_obj();
+}
+
+
+sub _build__blast_database {
+ my ($self) = @_;
+ return $self->_makeblastdb_obj->output_database;
+}
+
+sub _build__makeblastdb_obj {
+ my ($self) = @_;
+ my $blast_database =
+ Bio::Roary::External::Makeblastdb->new( fasta_file => $self->fasta_file, exec => $self->makeblastdb_exec, job_runner => $self->job_runner, cpus => $self->cpus );
+ $blast_database->run();
+ return $blast_database;
+}
+
+sub _build__chunk_fasta_file_obj {
+ my ($self) = @_;
+ return Bio::Roary::ChunkFastaFile->new( fasta_file => $self->fasta_file, );
+}
+
+sub _build__sequence_file_names {
+ my ($self) = @_;
+ return $self->_chunk_fasta_file_obj->sequence_file_names;
+}
+
+sub _build__working_directory_name {
+ my ($self) = @_;
+ return $self->_working_directory->dirname();
+}
+
+sub _build_blast_results_file_name {
+ my ($self) = @_;
+ return join( '/', ( $self->_working_directory_name, 'blast_results' ) );
+}
+
+sub _combine_blast_results {
+ my ( $self, $output_files ) = @_;
+ for my $output_file ( @{$output_files} ) {
+ Bio::Roary::Exceptions::FileNotFound->throw( error => "Cant find blast results: " . $output_file )
+ unless ( -e $output_file );
+ }
+ my $output_files_param = join( ' ', @{$output_files} );
+ system( "cat $output_files_param > " . $self->blast_results_file_name );
+ return 1;
+}
+
+sub _build_memory_in_mb
+{
+ my ($self) = @_;
+ my $filename = $self->fasta_file;
+ my $file_size = 3000;
+ if(-e $filename)
+ {
+ $file_size = -s $filename;
+ $file_size *=12;
+ $file_size = int($file_size/1000000);
+ $file_size = 3000 if($file_size < 3000);
+ }
+
+ return $file_size;
+}
+
+sub run {
+ my ($self) = @_;
+ my @expected_output_files;
+ my @commands_to_run;
+
+ for my $filename ( @{ $self->_sequence_file_names } ) {
+ my ( $filename_without_directory, $directories, $suffix ) = fileparse($filename);
+ my $output_seq_results_file =
+ join( '/', ( $self->_working_directory_name, $filename_without_directory . '.out' ) );
+
+ my $blast_database = Bio::Roary::External::Blastp->new(
+ fasta_file => $filename,
+ blast_database => $self->_blast_database,
+ exec => $self->blastp_exec,
+ output_file => $output_seq_results_file,
+ perc_identity => $self->perc_identity
+ );
+ push( @expected_output_files, $output_seq_results_file );
+ push( @commands_to_run, $blast_database->_command_to_run() );
+ $self->logger->info( "Running command: " . $blast_database->_command_to_run() );
+ }
+ my $job_runner_obj = $self->_job_runner_class->new( commands_to_run => \@commands_to_run, memory_in_mb => $self->memory_in_mb, queue => $self->_queue, cpus => $self->cpus );
+ $job_runner_obj->run();
+ $self->logger->info( "Combining blast results" );
+ $self->_combine_blast_results(\@expected_output_files);
+ return 1;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/ParseGFFAnnotationRole.pm b/lib/Bio/Roary/ParseGFFAnnotationRole.pm
new file mode 100644
index 0000000..60cb4c1
--- /dev/null
+++ b/lib/Bio/Roary/ParseGFFAnnotationRole.pm
@@ -0,0 +1,32 @@
+package Bio::Roary::ParseGFFAnnotationRole;
+
+# ABSTRACT: A role for parsing a gff file efficiently
+
+=head1 SYNOPSIS
+
+with 'Bio::Roary::ParseGFFAnnotationRole';
+
+=cut
+use Moose::Role;
+use Bio::Tools::GFF;
+
+has 'gff_file' => ( is => 'ro', isa => 'Str', required => 1 );
+
+has '_tags_to_filter' => ( is => 'ro', isa => 'Str', default => '(CDS|ncRNA|tRNA|tmRNA|rRNA)' );
+has '_gff_parser' => ( is => 'ro', isa => 'Bio::Tools::GFF', lazy => 1, builder => '_build__gff_parser' );
+has '_awk_filter' => ( is => 'ro', isa => 'Str', lazy => 1, builder => '_build__awk_filter' );
+
+sub _gff_fh_input_string {
+ my ($self) = @_;
+ return 'sed -n \'/##gff-version 3/,/##FASTA/p\' '.$self->gff_file.'| grep -v \'##FASTA\''." | " . $self->_awk_filter;
+}
+
+sub _build__awk_filter {
+ my ($self) = @_;
+ return
+ 'awk \'BEGIN {FS="\t"};{ if ($3 ~/'
+ . $self->_tags_to_filter
+ . '/) print $9;}\' ';
+}
+
+1;
diff --git a/lib/Bio/Roary/PostAnalysis.pm b/lib/Bio/Roary/PostAnalysis.pm
new file mode 100644
index 0000000..0997684
--- /dev/null
+++ b/lib/Bio/Roary/PostAnalysis.pm
@@ -0,0 +1,353 @@
+package Bio::Roary::PostAnalysis;
+
+# ABSTRACT: Post analysis of pan genomes
+
+=head1 SYNOPSIS
+
+Create a pan genome
+
+=cut
+
+use Moose;
+use File::Copy;
+use Bio::Roary::InflateClusters;
+use Bio::Roary::AnalyseGroups;
+use Bio::Roary::GroupLabels;
+use Bio::Roary::AnnotateGroups;
+use Bio::Roary::GroupStatistics;
+use Bio::Roary::Output::GroupsMultifastasNucleotide;
+use Bio::Roary::Output::NumberOfGroups;
+use Bio::Roary::OrderGenes;
+use Bio::Roary::Output::EmblGroups;
+use Bio::Roary::SplitGroups;
+use Bio::Roary::AccessoryBinaryFasta;
+use Bio::Roary::External::Fasttree;
+use Bio::Roary::AccessoryClustering;
+use Bio::Roary::AssemblyStatistics;
+use Log::Log4perl qw(:easy);
+
+has 'fasta_files' => ( is => 'rw', isa => 'ArrayRef', required => 1 );
+has 'input_files' => ( is => 'rw', isa => 'ArrayRef', required => 1 );
+has 'output_filename' => ( is => 'rw', isa => 'Str', default => 'clustered_proteins' );
+has 'output_pan_geneome_filename' => ( is => 'rw', isa => 'Str', default => 'pan_genome.fa' );
+has 'output_statistics_filename' => ( is => 'rw', isa => 'Str', default => 'gene_presence_absence.csv' );
+has 'output_multifasta_files' => ( is => 'ro', isa => 'Bool', default => 0 );
+has 'verbose_stats' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'verbose' => ( is => 'rw', isa => 'Bool', default => 0 );
+has 'cpus' => ( is => 'ro', isa => 'Int', default => 1 );
+
+has 'clusters_filename' => ( is => 'rw', isa => 'Str', required => 1 );
+has 'dont_delete_files' => ( is => 'ro', isa => 'Bool', default => 0 );
+has 'dont_split_groups' => ( is => 'ro', isa => 'Bool', default => 0 );
+has 'dont_create_rplots' => ( is => 'rw', isa => 'Bool', default => 1 );
+has 'group_limit' => ( is => 'rw', isa => 'Num', default => 50000 );
+
+has '_output_mcl_filename' => ( is => 'ro', isa => 'Str', default => '_uninflated_mcl_groups' );
+has '_output_inflate_unsplit_clusters_filename' => ( is => 'ro', isa => 'Str', default => '_inflated_unsplit_mcl_groups' );
+has '_output_inflate_clusters_filename' => ( is => 'ro', isa => 'Str', default => '_inflated_mcl_groups' );
+has '_output_group_labels_filename' => ( is => 'ro', isa => 'Str', default => '_labeled_mcl_groups' );
+has '_output_combined_filename' => ( is => 'ro', isa => 'Str', default => '_combined_files' );
+has '_input_cd_hit_groups_file' => ( is => 'ro', isa => 'Str', default => '_combined_files.groups' );
+has 'core_accessory_tab_output_filename' => ( is => 'ro', isa => 'Str', default => 'core_accessory.tab' );
+has 'accessory_tab_output_filename' => ( is => 'ro', isa => 'Str', default => 'accessory.tab' );
+has 'core_accessory_ordering_key' => ( is => 'ro', isa => 'Str', default => 'core_accessory_overall_order_filtered' );
+has 'accessory_ordering_key' => ( is => 'ro', isa => 'Str', default => 'accessory_overall_order_filtered' );
+has 'core_definition' => ( is => 'ro', isa => 'Num', default => 1.0 );
+has 'pan_genome_reference_filename' => ( is => 'ro', isa => 'Str', default => 'pan_genome_reference.fa' );
+
+has '_inflate_clusters_obj' => ( is => 'ro', isa => 'Bio::Roary::InflateClusters', lazy => 1, builder => '_build__inflate_clusters_obj' );
+has '_group_labels_obj' => ( is => 'ro', isa => 'Bio::Roary::GroupLabels', lazy => 1, builder => '_build__group_labels_obj' );
+has '_annotate_groups_obj' => ( is => 'ro', isa => 'Bio::Roary::AnnotateGroups', lazy => 1, builder => '_build__annotate_groups_obj' );
+has '_analyse_groups_obj' => ( is => 'ro', isa => 'Bio::Roary::AnalyseGroups', lazy => 1, builder => '_build__analyse_groups_obj' );
+has '_order_genes_obj' => ( is => 'ro', isa => 'Bio::Roary::OrderGenes', lazy => 1, builder => '_build__order_genes_obj' );
+has '_group_statistics_obj' => ( is => 'ro', isa => 'Bio::Roary::GroupStatistics', lazy => 1, builder => '_build__group_statistics_obj' );
+has '_number_of_groups_obj' =>
+ ( is => 'ro', isa => 'Bio::Roary::Output::NumberOfGroups', lazy => 1, builder => '_build__number_of_groups_obj' );
+has '_accessory_binary_fasta' =>
+ ( is => 'ro', isa => 'Bio::Roary::AccessoryBinaryFasta', lazy => 1, builder => '_build__accessory_binary_fasta' );
+has '_groups_multifastas_nuc_obj' =>
+ ( is => 'ro', isa => 'Bio::Roary::Output::GroupsMultifastasNucleotide', lazy => 1, builder => '_build__groups_multifastas_nuc_obj' );
+has '_split_groups_obj' => ( is => 'ro', isa => 'Bio::Roary::SplitGroups', lazy => 1, builder => '_build__split_groups_obj' );
+has '_accessory_binary_tree' =>
+ ( is => 'ro', isa => 'Bio::Roary::External::Fasttree', lazy => 1, builder => '_build__accessory_binary_tree' );
+has '_accessory_clustering' =>
+ ( is => 'ro', isa => 'Maybe[Bio::Roary::AccessoryClustering]', lazy => 1, builder => '_build__accessory_clustering' );
+has '_assembly_statistics' => ( is => 'ro', isa => 'Bio::Roary::AssemblyStatistics', lazy => 1, builder => '_build__assembly_statistics' );
+
+has 'logger' => ( is => 'ro', lazy => 1, builder => '_build_logger' );
+
+sub _build_logger {
+ my ($self) = @_;
+ Log::Log4perl->easy_init( level => $ERROR );
+ my $logger = get_logger();
+ return $logger;
+}
+
+sub run {
+ my ($self) = @_;
+
+ $self->logger->info("Reinflate clusters");
+ $self->_inflate_clusters_obj->inflate();
+
+ $self->logger->info("Split groups with paralogs");
+ ## SPLIT GROUPS WITH PARALOGS ##
+ if ( $self->dont_split_groups ) {
+ move( $self->_output_inflate_unsplit_clusters_filename, $self->_output_inflate_clusters_filename );
+ }
+ else {
+ $self->_split_groups_obj->split_groups;
+ }
+
+ $self->logger->info("Labelling the groups");
+ $self->_group_labels_obj->add_labels();
+
+ $self->logger->info("Transfering the annotation to the groups");
+ $self->_annotate_groups_obj->reannotate;
+
+ $self->logger->info("Creating accessory binary gene presence and absence fasta");
+ $self->_accessory_binary_fasta->create_accessory_binary_fasta;
+
+ $self->logger->info("Creating accessory binary gene presence and absence tree");
+ $self->_accessory_binary_tree->run;
+
+ $self->logger->info("Creating accessory gene presence and absence clusters");
+ if ( $self->_accessory_clustering ) {
+ $self->_accessory_clustering->sample_weights;
+ }
+
+ $self->logger->info("Creating the spreadsheet with gene presence and absence");
+ $self->_group_statistics_obj->create_spreadsheet;
+ $self->_group_statistics_obj->create_rtab;
+
+ $self->logger->info("Creating summary statistics of the spreadsheet");
+ $self->_assembly_statistics->create_summary_output;
+
+ $self->logger->info("Creating tab files for R");
+ $self->_number_of_groups_obj->create_output_files;
+
+ system("create_pan_genome_plots.R") unless ( $self->dont_create_rplots == 1 );
+
+ $self->logger->info("Create EMBL files");
+ $self->_create_embl_files;
+
+ my $clusters_not_exceeded = 1;
+ if ( $self->output_multifasta_files ) {
+ $self->logger->info("Creating files with the nucleotide sequences for every cluster");
+ $clusters_not_exceeded = $self->_groups_multifastas_nuc_obj->create_files();
+ }
+
+ $self->_delete_intermediate_files;
+ if ( $clusters_not_exceeded == 0 && $self->output_multifasta_files ) {
+ $self->logger->error("Exiting early because number of clusters is too high");
+ exit();
+ }
+}
+
+sub _build__assembly_statistics {
+ my ($self) = @_;
+ return Bio::Roary::AssemblyStatistics->new(
+ spreadsheet => $self->_group_statistics_obj->output_filename,
+ core_definition => $self->core_definition,
+ logger => $self->logger
+ );
+}
+
+sub _build__accessory_clustering {
+ my ($self) = @_;
+ if ( ( -e $self->_accessory_binary_fasta->output_filename ) && ( -s $self->_accessory_binary_fasta->output_filename > 5 ) ) {
+ $self->logger->info( $self->_accessory_binary_fasta->output_filename );
+ return Bio::Roary::AccessoryClustering->new(
+ input_file => $self->_accessory_binary_fasta->output_filename,
+ cpus => $self->cpus,
+ logger => $self->logger
+ );
+ }
+ else {
+ $self->logger->info("Theres no accessory binary file so skipping accessory binary clustering");
+ return undef;
+ }
+
+}
+
+sub _build__accessory_binary_tree {
+ my ($self) = @_;
+ return Bio::Roary::External::Fasttree->new(
+ input_file => $self->_accessory_binary_fasta->output_filename,
+ verbose => $self->verbose,
+ logger => $self->logger
+ );
+}
+
+sub _build__accessory_binary_fasta {
+ my ($self) = @_;
+ return Bio::Roary::AccessoryBinaryFasta->new(
+ input_files => $self->fasta_files,
+ annotate_groups_obj => $self->_annotate_groups_obj,
+ analyse_groups_obj => $self->_analyse_groups_obj,
+ logger => $self->logger
+ );
+}
+
+sub _build__split_groups_obj {
+ my ($self) = @_;
+ return Bio::Roary::SplitGroups->new(
+ groupfile => $self->_output_inflate_unsplit_clusters_filename,
+ gff_files => $self->input_files,
+ fasta_files => $self->fasta_files,
+ outfile => $self->_output_inflate_clusters_filename,
+ dont_delete => $self->dont_delete_files,
+ logger => $self->logger
+ );
+}
+
+sub _build__number_of_groups_obj {
+ my ($self) = @_;
+ return Bio::Roary::Output::NumberOfGroups->new(
+ group_statistics_obj => $self->_group_statistics_obj,
+ groups_to_contigs => $self->_order_genes_obj->groups_to_contigs,
+ annotate_groups_obj => $self->_annotate_groups_obj,
+ core_definition => $self->core_definition,
+ logger => $self->logger
+ );
+}
+
+sub _build__group_statistics_obj {
+ my ($self) = @_;
+ return Bio::Roary::GroupStatistics->new(
+ output_filename => $self->output_statistics_filename,
+ annotate_groups_obj => $self->_annotate_groups_obj,
+ analyse_groups_obj => $self->_analyse_groups_obj,
+ groups_to_contigs => $self->_order_genes_obj->groups_to_contigs,
+ _verbose => $self->verbose_stats,
+ logger => $self->logger
+ );
+}
+
+sub _build__order_genes_obj {
+ my ($self) = @_;
+ if ( defined( $self->_accessory_clustering ) ) {
+ return Bio::Roary::OrderGenes->new(
+ analyse_groups_obj => $self->_analyse_groups_obj,
+ gff_files => $self->input_files,
+ core_definition => $self->core_definition,
+ sample_weights => $self->_accessory_clustering->sample_weights,
+ samples_to_clusters => $self->_accessory_clustering->samples_to_clusters,
+ logger => $self->logger
+ );
+ }
+ else {
+ return Bio::Roary::OrderGenes->new(
+ analyse_groups_obj => $self->_analyse_groups_obj,
+ gff_files => $self->input_files,
+ core_definition => $self->core_definition,
+ logger => $self->logger
+ );
+ }
+}
+
+sub _build__group_labels_obj {
+ my ($self) = @_;
+ return Bio::Roary::GroupLabels->new(
+ groups_filename => $self->_output_inflate_clusters_filename,
+ output_filename => $self->_output_group_labels_filename,
+ logger => $self->logger
+ );
+}
+
+sub _build__annotate_groups_obj {
+ my ($self) = @_;
+ return Bio::Roary::AnnotateGroups->new(
+ gff_files => $self->input_files,
+ output_filename => $self->output_filename,
+ groups_filename => $self->_output_group_labels_filename,
+ logger => $self->logger
+ );
+}
+
+sub _build__analyse_groups_obj {
+ my ($self) = @_;
+ return Bio::Roary::AnalyseGroups->new(
+ fasta_files => $self->fasta_files,
+ groups_filename => $self->output_filename,
+ logger => $self->logger
+ );
+}
+
+sub _build__inflate_clusters_obj {
+ my ($self) = @_;
+ return Bio::Roary::InflateClusters->new(
+ clusters_filename => $self->clusters_filename,
+ cdhit_groups_filename => $self->_input_cd_hit_groups_file,
+ mcl_filename => $self->_output_mcl_filename,
+ output_file => $self->_output_inflate_unsplit_clusters_filename,
+ logger => $self->logger
+ );
+}
+
+sub _build__groups_multifastas_nuc_obj {
+ my ($self) = @_;
+ return Bio::Roary::Output::GroupsMultifastasNucleotide->new(
+ output_multifasta_files => $self->output_multifasta_files,
+ gff_files => $self->input_files,
+ annotate_groups => $self->_annotate_groups_obj,
+ group_names => $self->_analyse_groups_obj->_groups,
+ group_limit => $self->group_limit,
+ core_definition => $self->core_definition,
+ dont_delete_files => $self->dont_delete_files,
+ logger => $self->logger
+ );
+}
+
+sub _create_embl_files {
+ my ($self) = @_;
+ my $core_accessory_tab_obj = Bio::Roary::Output::EmblGroups->new(
+ output_filename => $self->core_accessory_tab_output_filename,
+ annotate_groups_obj => $self->_annotate_groups_obj,
+ analyse_groups_obj => $self->_analyse_groups_obj,
+ ordering_key => $self->core_accessory_ordering_key,
+ groups_to_contigs => $self->_order_genes_obj->groups_to_contigs,
+ logger => $self->logger
+ );
+ $core_accessory_tab_obj->create_files;
+
+ my $accessory_tab_obj = Bio::Roary::Output::EmblGroups->new(
+ output_filename => $self->accessory_tab_output_filename,
+ annotate_groups_obj => $self->_annotate_groups_obj,
+ analyse_groups_obj => $self->_analyse_groups_obj,
+ ordering_key => $self->accessory_ordering_key,
+ groups_to_contigs => $self->_order_genes_obj->groups_to_contigs,
+ logger => $self->logger
+ );
+ $accessory_tab_obj->create_files;
+}
+
+sub _delete_intermediate_files {
+ my ($self) = @_;
+ return if ( $self->dont_delete_files == 1 );
+ $self->logger->info("Cleaning up files");
+
+ for my $fasta_file ( @{ $self->fasta_files } ) {
+ unlink($fasta_file) if ( -e $fasta_file );
+ }
+
+ unlink( $self->_output_mcl_filename );
+ unlink( $self->_output_inflate_clusters_filename );
+ unlink( $self->_output_group_labels_filename );
+ unlink( $self->_output_combined_filename );
+ unlink( $self->clusters_filename );
+ unlink( $self->clusters_filename . '.clstr' );
+ unlink( $self->clusters_filename . '.bak.clstr' );
+ unlink('_gff_files');
+ unlink('_fasta_files');
+ unlink('_clustered_filtered.fa');
+ unlink( $self->_input_cd_hit_groups_file );
+ unlink('database_masking.asnb');
+ unlink('_clustered');
+ unlink('_accessory_clusters');
+ unlink('_accessory_clusters.clstr');
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/PrepareInputFiles.pm b/lib/Bio/Roary/PrepareInputFiles.pm
new file mode 100644
index 0000000..bedb9bb
--- /dev/null
+++ b/lib/Bio/Roary/PrepareInputFiles.pm
@@ -0,0 +1,116 @@
+package Bio::Roary::PrepareInputFiles;
+
+# ABSTRACT: Take in a mixture of FASTA and GFF input files and output FASTA proteomes only
+
+=head1 SYNOPSIS
+
+Take in a mixture of FASTA and GFF input files and output FASTA proteomes only
+ use Bio::Roary::PrepareInputFiles;
+
+ my $obj = Bio::Roary::PrepareInputFiles->new(
+ input_files => ['abc.gff','ddd.faa'],
+ );
+ $obj->fasta_files;
+
+=cut
+
+use Moose;
+use Bio::Roary::Exceptions;
+use Bio::Roary::ExtractProteomeFromGFFs;
+use Bio::Roary::FilterUnknownsFromFasta;
+use Cwd qw(getcwd);
+use File::Temp;
+
+has 'input_files' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'job_runner' => ( is => 'ro', isa => 'Str', default => 'Local' );
+has 'cpus' => ( is => 'ro', isa => 'Int', default => 1 );
+has '_input_gff_files' => ( is => 'ro', isa => 'Maybe[ArrayRef]', lazy => 1, builder => '_build__input_gff_files' );
+has '_input_fasta_files' => ( is => 'ro', isa => 'Maybe[ArrayRef]', lazy => 1, builder => '_build__input_fasta_files' );
+has '_input_fasta_files_filtered' =>
+ ( is => 'ro', isa => 'Maybe[ArrayRef]', lazy => 1, builder => '_build__input_fasta_files_filtered' );
+has '_input_fasta_files_filtered_obj' =>
+ ( is => 'ro', isa => 'Bio::Roary::FilterUnknownsFromFasta', lazy => 1, builder => '_build__input_fasta_files_filtered_obj' );
+
+has '_derived_fasta_files' =>
+ ( is => 'ro', isa => 'Maybe[ArrayRef]', lazy => 1, builder => '_build__derived_fasta_files' );
+has '_extract_proteome_obj' => (
+ is => 'ro',
+ isa => 'Bio::Roary::ExtractProteomeFromGFFs',
+ lazy => 1,
+ builder => '_build__extract_proteome_obj'
+);
+has 'apply_unknowns_filter' => ( is => 'rw', isa => 'Bool', default => 1 );
+has 'translation_table' => ( is => 'rw', isa => 'Int', default => 11 );
+has 'verbose' => ( is => 'rw', isa => 'Bool', default => 0 );
+has '_fasta_filter_obj' => ( is => 'ro', isa => 'Bio::Roary::FilterUnknowsFromFasta', lazy => 1, builder => '_fasta_filter_obj' );
+has 'working_directory' => ( is => 'ro', isa => 'File::Temp::Dir', default => sub { File::Temp->newdir( DIR => getcwd, CLEANUP => 1 ); } );
+
+sub _build__input_gff_files {
+ my ($self) = @_;
+ my @gff_files = grep( /\.gff$/, @{ $self->input_files } );
+ return \@gff_files;
+}
+
+sub _build__input_fasta_files {
+ my ($self) = @_;
+ my @fasta_files = grep( !/\.gff$/, @{ $self->input_files } );
+ return \@fasta_files;
+}
+
+sub _build__input_fasta_files_filtered_obj {
+ my ($self) = @_;
+ return Bio::Roary::FilterUnknownsFromFasta->new( fasta_files => $self->_input_fasta_files );
+}
+
+sub _build__input_fasta_files_filtered
+{
+ my ($self) = @_;
+ return undef if ( !defined( $self->_input_fasta_files ) );
+ return $self->_input_fasta_files_filtered_obj->filtered_fasta_files();
+}
+
+sub _build__extract_proteome_obj {
+ my ($self) = @_;
+ return Bio::Roary::ExtractProteomeFromGFFs->new(
+ gff_files => $self->_input_gff_files,
+ job_runner => $self->job_runner,
+ apply_unknowns_filter => $self->apply_unknowns_filter,
+ translation_table => $self->translation_table,
+ cpus => $self->cpus,
+ verbose => $self->verbose,
+ working_directory => $self->working_directory,
+ );
+}
+
+sub _build__derived_fasta_files {
+ my ($self) = @_;
+ return undef if ( !defined( $self->_input_gff_files ) );
+ return $self->_extract_proteome_obj->fasta_files();
+}
+
+sub fasta_files {
+ my ($self) = @_;
+ my @output_fasta_files = ( @{ $self->_input_fasta_files_filtered }, @{ $self->_derived_fasta_files } );
+ return \@output_fasta_files;
+}
+
+sub lookup_fasta_files_from_unknown_input_files {
+ my ( $self, $input_files ) = @_;
+ $self->fasta_files;
+
+ my @output_fasta_files;
+ for my $input_file ( @{$input_files} ) {
+ if ( defined( $self->_extract_proteome_obj->fasta_files_to_gff_files->{$input_file} ) ) {
+ push( @output_fasta_files, $self->_extract_proteome_obj->fasta_files_to_gff_files->{$input_file} );
+ }
+ else {
+ push( @output_fasta_files, $self->_input_fasta_files_filtered_obj->input_fasta_to_output_fasta->{$input_file} );
+ }
+ }
+ return \@output_fasta_files;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/PresenceAbsenceMatrix.pm b/lib/Bio/Roary/PresenceAbsenceMatrix.pm
new file mode 100644
index 0000000..0796aeb
--- /dev/null
+++ b/lib/Bio/Roary/PresenceAbsenceMatrix.pm
@@ -0,0 +1,84 @@
+package Bio::Roary::PresenceAbsenceMatrix;
+
+# ABSTRACT: Create a matrix with presence and absence
+
+=head1 SYNOPSIS
+
+Create a matrix with presence and absence. Since its computationally intensive to generate the inputs, calculate them once
+in the GroupStatistics module and pass them through.
+ use Bio::Roary::PresenceAbsenceMatrix;
+
+ my $obj = Bio::Roary::PresenceAbsenceMatrix->new(
+ annotate_groups_obj => $annotate_groups_obj,
+ output_filename => 'gene_presence_absence.Rtab',
+ sorted_file_names => $sorted_file_names,
+ groups_to_files => $groups_to_files,
+ num_files_in_groups => $num_files_in_groups,
+ sample_headers => $sample_headers,
+ );
+ $obj->create_matrix_file;
+
+=cut
+
+use Moose;
+use Text::CSV;
+use Bio::SeqIO;
+use Bio::Roary::Exceptions;
+use Bio::Roary::AnnotateGroups;
+
+has 'annotate_groups_obj' => ( is => 'ro', isa => 'Bio::Roary::AnnotateGroups', required => 1 );
+has 'sorted_file_names' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'groups_to_files' => ( is => 'ro', isa => 'HashRef', required => 1 );
+has 'num_files_in_groups' => ( is => 'ro', isa => 'HashRef', required => 1 );
+has 'sample_headers' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'output_filename' => ( is => 'ro', isa => 'Str', default => 'gene_presence_absence.Rtab' );
+
+has '_output_fh' => ( is => 'ro', lazy => 1, builder => '_build__output_fh' );
+has '_text_csv_obj' => ( is => 'ro', isa => 'Text::CSV', lazy => 1, builder => '_build__text_csv_obj' );
+
+sub _build__output_fh {
+ my ($self) = @_;
+ open( my $fh, '>', $self->output_filename )
+ or Bio::Roary::Exceptions::CouldntWriteToFile->throw( error => "Couldnt write output file:" . $self->output_filename );
+ return $fh;
+}
+
+sub _build__text_csv_obj {
+ my ($self) = @_;
+ return Text::CSV->new( { binary => 1, always_quote => 0, sep_char => "\t", eol => "\r\n" } );
+}
+
+sub create_matrix_file {
+ my ($self) = @_;
+
+ # Header row
+ unshift @{ $self->sample_headers }, 'Gene';
+ $self->_text_csv_obj->print( $self->_output_fh, $self->sample_headers );
+
+ for my $group ( sort { $self->num_files_in_groups->{$b} <=> $self->num_files_in_groups->{$a} || $a cmp $b }
+ keys %{ $self->num_files_in_groups } )
+ {
+ my @row;
+ my $annotated_group_name = $self->annotate_groups_obj->_groups_to_consensus_gene_names->{$group};
+ push( @row, $annotated_group_name );
+ for my $filename ( @{ $self->sorted_file_names } ) {
+ my $group_to_file_genes = $self->groups_to_files->{$group}->{$filename};
+
+ if ( defined($group_to_file_genes) && @{$group_to_file_genes} > 0 ) {
+ push( @row, 1 );
+ next;
+ }
+ else {
+ push( @row, 0 );
+ }
+ }
+ $self->_text_csv_obj->print( $self->_output_fh, \@row );
+ }
+ close( $self->_output_fh );
+ return $self;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/QC/Report.pm b/lib/Bio/Roary/QC/Report.pm
new file mode 100644
index 0000000..3baa8b2
--- /dev/null
+++ b/lib/Bio/Roary/QC/Report.pm
@@ -0,0 +1,241 @@
+package Bio::Roary::QC::Report;
+
+# ABSTRACT: generate a report based on kraken output
+
+=head1 SYNOPSIS
+
+=cut
+
+use Moose;
+use File::Temp;
+use File::Path 'rmtree';
+use Cwd;
+use File::Basename;
+with 'Bio::Roary::JobRunner::Role';
+
+has 'input_files' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'kraken_exec' => ( is => 'ro', isa => 'Str', default => 'kraken' );
+has 'kraken_report_exec' => ( is => 'ro', isa => 'Str', default => 'kraken-report' );
+has 'kraken_db' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'outfile' => ( is => 'rw', isa => 'Str', default => 'qc_report.csv' );
+has '_kraken_data' => ( is => 'rw', isa => 'ArrayRef', lazy_build => 1 );
+has '_header' => ( is => 'rw', isa => 'Str', lazy_build => 1 );
+has 'kraken_memory' => ( is => 'rw', isa => 'Int', default => 2000 );
+
+has '_tmp_directory_obj' => ( is => 'rw', lazy_build => 1 );
+has '_tmp_directory' => ( is => 'rw', lazy_build => 1, isa => 'Str', );
+
+
+sub _nuc_fasta_filename
+{
+ my ($self, $gff) = @_;
+
+ my $prefix = basename( $gff, ".gff" );
+ my $outfile = $self->_tmp_directory . "/$prefix.fna";
+ return $outfile;
+}
+
+sub _extract_nuc_fasta_cmd {
+ my ($self, $gff) = @_;
+ my $outfile = $self->_nuc_fasta_filename($gff);
+ my $cmd = "sed -n '/##FASTA/,//p' $gff | grep -v \'##FASTA\' > $outfile";
+
+ return $cmd;
+}
+
+sub _extract_nuc_files_from_all_gffs
+{
+ my ($self) = @_;
+ my @nuc_files;
+ my @commands_to_run;
+ for my $input_file(@{$self->input_files})
+ {
+ push(@nuc_files,$self->_nuc_fasta_filename($input_file));
+ push(@commands_to_run,$self->_extract_nuc_fasta_cmd($input_file));
+ }
+ my $kraken_runner_obj = $self->_job_runner_class->new(
+ commands_to_run => \@commands_to_run,
+ memory_in_mb => $self->kraken_memory,
+ verbose => $self->verbose,
+ cpus => $self->cpus
+ );
+ $kraken_runner_obj->run();
+ return \@nuc_files;
+}
+
+sub _kraken_cmd {
+ my ( $self, $a, $kraken_output ) = @_;
+
+ my $kcmd = $self->kraken_exec .
+ " --fasta-input ".
+ " --preload ".
+ " --db " . $self->kraken_db .
+ " --output $kraken_output $a > /dev/null 2>&1";
+ return $kcmd;
+}
+
+sub _kraken_report_cmd {
+ my ( $self, $k, $report_output ) = @_;
+
+ my $krcmd = $self->kraken_report_exec .
+ " --db " . $self->kraken_db .
+ " $k > $report_output";
+ return $krcmd;
+}
+
+sub _kraken_output_filename
+{
+ my ( $self, $assembly ) = @_;
+ my $kraken_output = $assembly;
+ $kraken_output =~ s/fna$/kraken/;
+ return $kraken_output;
+}
+
+sub _run_kraken_on_nuc_files
+{
+ my ( $self, $nuc_files ) = @_;
+ my @kraken_output_files;
+ my @commands_to_run;
+ for my $nuc_file(@{$nuc_files})
+ {
+ my $kraken_output = $self->_kraken_output_filename($nuc_file);
+ push(@kraken_output_files, $kraken_output );
+ push(@commands_to_run, $self->_kraken_cmd( $nuc_file, $kraken_output ));
+ }
+
+ my $kraken_runner_obj = $self->_job_runner_class->new(
+ commands_to_run => \@commands_to_run,
+ memory_in_mb => $self->kraken_memory,
+ verbose => $self->verbose,
+ cpus => $self->cpus
+ );
+ $kraken_runner_obj->run();
+
+ for my $filename(@{$nuc_files})
+ {
+ unlink($filename);
+ }
+
+ return \@kraken_output_files;
+}
+
+sub _kraken_report_output_filename
+{
+ my ( $self, $assembly ) = @_;
+ return $assembly.".report";
+}
+
+sub _run_kraken_report_on_kraken_files
+{
+ my ( $self, $kraken_files ) = @_;
+
+ my @kraken_report_output_files;
+ my @commands_to_run;
+ for my $nuc_file(@{$kraken_files})
+ {
+ my $kraken_output = $self->_kraken_report_output_filename($nuc_file);
+ push(@kraken_report_output_files, $kraken_output );
+ push(@commands_to_run, $self->_kraken_report_cmd( $nuc_file, $kraken_output ));
+ }
+
+ my $kraken_runner_obj = $self->_job_runner_class->new(
+ commands_to_run => \@commands_to_run,
+ memory_in_mb => $self->kraken_memory,
+ verbose => $self->verbose,
+ cpus => $self->cpus
+ );
+ $kraken_runner_obj->run();
+ for my $filename(@{$kraken_files})
+ {
+ unlink($filename);
+ }
+ return \@kraken_report_output_files;
+}
+
+sub _build__kraken_data {
+ my $self = shift;
+ my $nuc_files = $self->_extract_nuc_files_from_all_gffs();
+ my $kraken_files = $self->_run_kraken_on_nuc_files($nuc_files);
+ my $kraken_report_files = $self->_run_kraken_report_on_kraken_files( $kraken_files );
+
+ return $self->_parse_kraken_reports($kraken_report_files);
+}
+
+sub _parse_kraken_reports
+{
+ my ( $self, $kraken_report_files ) = @_;
+
+ my @report_rows;
+ for my $kraken_report(@{$kraken_report_files})
+ {
+ push(@report_rows, $self->_parse_kraken_report($kraken_report));
+ }
+
+ for my $kraken_report(@{$kraken_report_files})
+ {
+ unlink($kraken_report);
+ }
+
+ return \@report_rows;
+}
+
+sub _parse_kraken_report {
+ my ( $self, $kraken_report ) = @_;
+
+ # parse report
+ open( my $report_fh, '<', $kraken_report );
+
+ my $sample_name = $kraken_report;
+ $sample_name =~ s/.report$//;
+ $sample_name =~ s/.kraken$//;
+ my($sample_base_name, $dirs, $suffix) = fileparse($sample_name);
+
+ my ( $top_genus, $top_species );
+ while ( <$report_fh> ){
+ my @parts = split( "\t" );
+ chomp @parts;
+
+ $top_genus = $parts[5] if ( (! defined $top_genus) && $parts[3] eq 'G' );
+ $top_species = $parts[5] if ( (! defined $top_species) && $parts[3] eq 'S' );
+
+ last if (defined $top_genus && defined $top_species);
+ }
+ close($report_fh);
+
+ $top_genus ||= "not_found";
+ $top_genus =~ s/^\s+//g;
+ $top_species ||= "not_found";
+ $top_species =~ s/^\s+//g;
+
+ return [ $sample_base_name, $top_genus, $top_species ];
+}
+
+
+sub _build__header {
+ return join( ',', ( 'Sample', 'Genus', 'Species' ) );
+}
+
+sub _build__tmp_directory_obj {
+ return File::Temp->newdir(DIR => getcwd, CLEANUP => 1 );
+}
+
+sub _build__tmp_directory {
+ my $self = shift;
+ return $self->_tmp_directory_obj->dirname();
+}
+
+sub report {
+ my $self = shift;
+
+ open( OUTFILE, '>', $self->outfile );
+ print OUTFILE $self->_header . "\n";
+ for my $line ( @{ $self->_kraken_data } ){
+ print OUTFILE join( ',', @{ $line } ) . "\n";
+ }
+ close OUTFILE;
+}
+
+
+__PACKAGE__->meta->make_immutable;
+no Moose;
+1;
diff --git a/lib/Bio/Roary/ReformatInputGFFs.pm b/lib/Bio/Roary/ReformatInputGFFs.pm
new file mode 100644
index 0000000..86289ca
--- /dev/null
+++ b/lib/Bio/Roary/ReformatInputGFFs.pm
@@ -0,0 +1,162 @@
+package Bio::Roary::ReformatInputGFFs;
+
+# ABSTRACT: Take in gff files and add suffix where a gene id is seen twice
+
+=head1 SYNOPSIS
+
+Take in gff files and add suffix where a gene id is seen twice
+ use Bio::Roary::ReformatInputGFFs;
+
+ my $obj = Bio::Roary::PrepareInputFiles->new(
+ gff_files => ['abc.gff','ddd.faa'],
+ );
+ $obj->fix_duplicate_gene_ids;
+ $obj->fixed_gff_files;
+
+=cut
+
+use Moose;
+use Bio::Roary::Exceptions;
+use Cwd;
+use Log::Log4perl qw(:easy);
+use Bio::Tools::GFF;
+use File::Path qw(make_path);
+use File::Basename;
+
+has 'gff_files' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'logger' => ( is => 'ro', lazy => 1, builder => '_build_logger' );
+has '_tags_to_filter' => ( is => 'ro', isa => 'Str', default => '(CDS|ncRNA|tRNA|tmRNA|rRNA)' );
+has 'output_directory' => ( is => 'ro', isa => 'Str', default => 'fixed_input_files' );
+has 'suffix_counter' => ( is => 'rw', isa => 'Int', default => 1 );
+
+has 'fixed_gff_files' => ( is => 'rw', isa => 'ArrayRef', default => sub { [] } );
+
+sub _build_logger {
+ my ($self) = @_;
+ Log::Log4perl->easy_init( level => $ERROR );
+ my $logger = get_logger();
+ return $logger;
+}
+
+sub fix_duplicate_gene_ids {
+ my ($self) = @_;
+
+ my %gene_ids_seen_before;
+ for my $file ( @{ $self->gff_files } ) {
+
+ my $ids_seen = 0;
+ my $ids_from_file = $self->_get_ids_for_gff_file($file);
+
+ if ( @{$ids_from_file} < 1 ) {
+ $self->logger->warn(
+ "Input GFF file doesnt contain annotation we can use so excluding it from the analysis: $file"
+ );
+ }
+ else {
+ for my $gene_id ( @{$ids_from_file} ) {
+ if ( $gene_ids_seen_before{$gene_id} ) {
+ $self->logger->warn(
+ "Input file contains duplicate gene IDs, attempting to fix by adding a unique suffix. New GFF in the fixed_input_files directory. $file "
+ );
+ my $updated_file = $self->_add_suffix_to_gene_ids_and_return_new_file($file);
+ push( @{ $self->fixed_gff_files }, $updated_file ) if ( defined($updated_file) );
+ $ids_seen = 1;
+ last;
+ }
+ $gene_ids_seen_before{$gene_id}++;
+ }
+ if ( $ids_seen == 0 ) {
+ push( @{ $self->fixed_gff_files }, $file );
+ }
+ }
+ }
+ return 1;
+}
+
+sub _add_suffix_to_gene_ids_and_return_new_file {
+ my ( $self, $input_file ) = @_;
+ my ( $filename, $directories, $suffix ) = fileparse( $input_file, qr/\.[^.]*/ );
+ make_path( $self->output_directory ) if ( !( -d $self->output_directory ) );
+ my $output_file = $self->output_directory . '/' . $filename . $suffix;
+
+ open( my $input_gff_fh, $input_file );
+ open( my $out_gff_fh, '>', $output_file );
+
+ my $found_fasta = 0;
+ while (<$input_gff_fh>) {
+ my $line = $_;
+
+ if ( $line =~ /^\#\#FASTA/ ) {
+ $found_fasta = 1;
+ }
+
+ if ( $line =~ /\#/ || $found_fasta == 1 ) {
+ print {$out_gff_fh} $line;
+ next;
+ }
+
+ my @cells = split( /\t/, $line );
+ my @tags = split( /;/, $cells[8] );
+ my $found_id = 0;
+ for ( my $i = 0 ; $i < @tags ; $i++ ) {
+ if ( $tags[$i] =~ /^(ID=["']?)([^;"']+)(["']?)/ ) {
+ my $current_id = $2;
+ $current_id .= '___' . $self->suffix_counter;
+ $tags[$i] = $1 . $current_id . $3;
+ $self->suffix_counter( $self->suffix_counter + 1 );
+ $found_id++;
+ last;
+ }
+ }
+ if ( $found_id == 0 ) {
+ unshift( @tags, 'ID=id___' . $self->suffix_counter );
+ $self->suffix_counter( $self->suffix_counter + 1 );
+ }
+ $cells[8] = join( ';', @tags );
+ print {$out_gff_fh} join( "\t", @cells );
+ }
+
+ if ( $found_fasta == 0 ) {
+ $self->logger->warn(
+ "Input GFF file doesnt appear to have the FASTA sequence at the end of the file so is being excluded from the analysis: $input_file" );
+ return undef;
+ }
+ close($out_gff_fh);
+ close($input_gff_fh);
+ return $output_file;
+}
+
+sub _get_ids_for_gff_file {
+ my ( $self, $file ) = @_;
+ my @gene_ids;
+ my $tags_regex = $self->_tags_to_filter;
+ my $gffio = Bio::Tools::GFF->new( -file => $file, -gff_version => 3 );
+ while ( my $feature = $gffio->next_feature() ) {
+ next if !( $feature->primary_tag =~ /$tags_regex/ );
+ my $gene_id = $self->_get_feature_id($feature);
+ push( @gene_ids, $gene_id ) if ( defined($gene_id) );
+ }
+ return \@gene_ids;
+}
+
+sub _get_feature_id {
+ my ( $self, $feature ) = @_;
+ my ( $gene_id, @junk );
+ if ( $feature->has_tag('ID') ) {
+ ( $gene_id, @junk ) = $feature->get_tag_values('ID');
+ }
+ elsif ( $feature->has_tag('locus_tag') ) {
+ ( $gene_id, @junk ) = $feature->get_tag_values('locus_tag');
+ }
+ else {
+ return undef;
+ }
+ $gene_id =~ s!["']!!g;
+ return undef if ( $gene_id eq "" );
+ return $gene_id;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/ReorderSpreadsheet.pm b/lib/Bio/Roary/ReorderSpreadsheet.pm
new file mode 100644
index 0000000..87a1a39
--- /dev/null
+++ b/lib/Bio/Roary/ReorderSpreadsheet.pm
@@ -0,0 +1,133 @@
+package Bio::Roary::ReorderSpreadsheet;
+
+# ABSTRACT: Take in a tree file and a spreadsheet and output a spreadsheet with reordered columns
+
+=head1 SYNOPSIS
+
+Take in a tree file and a spreadsheet and output a spreadsheet with reordered columns
+ use Bio::Roary::ReorderSpreadsheet;
+
+ my $obj = Bio::Roary::ReorderSpreadsheet->new(
+ tree_file => $tree_file,
+ spreadsheet => 'groups.csv'
+ );
+ $obj->reorder_spreadsheet();
+
+=cut
+
+use Moose;
+use Text::CSV;
+use Bio::Roary::SampleOrder;
+use Bio::Roary::GroupStatistics;
+with 'Bio::Roary::SpreadsheetRole';
+
+has 'tree_file' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'spreadsheet' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'tree_format' => ( is => 'ro', isa => 'Str', default => 'newick' );
+has 'output_filename' => ( is => 'ro', isa => 'Str', default => 'reordered_groups_stats.csv' );
+has 'search_strategy' => ( is => 'ro', isa => 'Str', default => 'depth' );
+has 'sortby' => ( is => 'ro', isa => 'Maybe[Str]');
+
+has '_sample_order' => ( is => 'ro', isa => 'ArrayRef', lazy => 1, builder => '_build__sample_order' );
+has '_column_mappings' => ( is => 'ro', isa => 'ArrayRef', lazy => 1, builder => '_build__column_mappings' );
+
+
+sub BUILD {
+ my ($self) = @_;
+ # read the headers first
+ $self->_column_mappings;
+}
+
+
+sub reorder_spreadsheet {
+ my ($self) = @_;
+
+ # make sure the file handle is at the start
+ seek($self->_input_spreadsheet_fh ,0,0);
+ while ( my $row = $self->_csv_parser->getline( $self->_input_spreadsheet_fh ) )
+ {
+ $self->_csv_output->print($self->_output_spreadsheet_fh, $self->_remap_columns($row));
+ }
+
+ close($self->_output_spreadsheet_fh);
+ close($self->_input_spreadsheet_fh);
+ return 1;
+}
+
+sub _remap_columns
+{
+ my ($self, $row) = @_;
+
+ my @output_row;
+ for(my $output_index = 0; $output_index < @{$self->_column_mappings}; $output_index++)
+ {
+ my $input_index = $self->_column_mappings->[$output_index];
+ push(@output_row, $row->[$input_index]);
+ }
+ return \@output_row;
+}
+
+sub _column_mappings_populate_fixed_headers
+{
+ my ($self, $column_mappings,$header_row) = @_;
+ my $column_counter = 0;
+ for($column_counter = 0; $column_counter < $self->_num_fixed_headers; $column_counter++)
+ {
+ push(@{$column_mappings}, $column_counter);
+ shift(@{$header_row});
+ }
+ return $column_counter;
+}
+
+sub _build__column_mappings
+{
+ my ($self) = @_;
+ my $header_row = $self->_csv_parser->getline( $self->_input_spreadsheet_fh );
+
+ my @column_mappings;
+ my $column_counter = $self->_column_mappings_populate_fixed_headers(\@column_mappings, $header_row);
+
+ # put the input column names into an array where the key is the name and the value is the order
+ my %input_sample_order;
+ for(my $i = 0; $i < @{$header_row}; $i++)
+ {
+ $input_sample_order{$header_row->[$i]} = $i + $column_counter;
+ }
+
+ # Go through the order of the samples from the tree and see if the headers exist
+ for my $sample_name (@{$self->_sample_order})
+ {
+ if(defined($input_sample_order{$sample_name}))
+ {
+ push(@column_mappings, $input_sample_order{$sample_name});
+ delete($input_sample_order{$sample_name});
+ }
+ $column_counter++;
+ }
+
+ # Add any columns not in the tree to the end
+ for my $sample_name (keys %input_sample_order)
+ {
+ push(@column_mappings, $input_sample_order{$sample_name});
+ delete($input_sample_order{$sample_name});
+ $column_counter++;
+ }
+ return \@column_mappings;
+}
+
+sub _build__sample_order {
+ my ($self) = @_;
+ my $obj = Bio::Roary::SampleOrder->new(
+ tree_file => $self->tree_file,
+ tree_format => $self->tree_format,
+ search_strategy => $self->search_strategy,
+ sortby => $self->sortby
+ );
+ return $obj->ordered_samples();
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
+
diff --git a/lib/Bio/Roary/SampleOrder.pm b/lib/Bio/Roary/SampleOrder.pm
new file mode 100644
index 0000000..dae0ddf
--- /dev/null
+++ b/lib/Bio/Roary/SampleOrder.pm
@@ -0,0 +1,50 @@
+package Bio::Roary::SampleOrder;
+
+# ABSTRACT: Take in a tree file and return an ordering of the samples
+
+=head1 SYNOPSIS
+
+Take in a tree file and return an ordering of the samples. Defaults to depth first search
+ use Bio::Roary::SampleOrder;
+
+ my $obj = Bio::Roary::SampleOrder->new(
+ tree_file => $tree_file,
+ );
+ $obj->ordered_samples();
+
+=cut
+
+use Moose;
+use Bio::TreeIO;
+
+has 'tree_file' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'tree_format' => ( is => 'ro', isa => 'Str', default => 'newick' );
+has 'ordered_samples' => ( is => 'ro', isa => 'ArrayRef', lazy => 1, builder => '_build_ordered_samples' );
+
+# 'b|breadth' first order or 'd|depth' first order
+has 'search_strategy' => ( is => 'ro', isa => 'Str', default => 'depth' );
+has 'sortby' => (is => 'ro', isa => 'Maybe[Str]');
+
+
+sub _build_ordered_samples {
+ my ($self) = @_;
+ my $input = Bio::TreeIO->new(
+ -file => $self->tree_file,
+ -format => $self->tree_format
+ );
+ my $tree = $input->next_tree;
+ my @taxa;
+ for my $leaf_node ( $tree->get_nodes($self->search_strategy,$self->sortby) ) {
+ if($leaf_node->is_Leaf)
+ {
+ push( @taxa, $leaf_node->id );
+ }
+ }
+ return \@taxa;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
+
diff --git a/lib/Bio/Roary/SequenceLengths.pm b/lib/Bio/Roary/SequenceLengths.pm
new file mode 100644
index 0000000..6f62fe1
--- /dev/null
+++ b/lib/Bio/Roary/SequenceLengths.pm
@@ -0,0 +1,43 @@
+package Bio::Roary::SequenceLengths;
+
+# ABSTRACT: Take in a fasta file and create a hash with the length of each sequence
+
+=head1 SYNOPSIS
+
+Add labels to the groups
+ use Bio::Roary::SequenceLengths;
+
+ my $obj = Bio::Roary::SequenceLengths->new(
+ fasta_file => 'abc.fa',
+ );
+ $obj->sequence_lengths;
+
+=cut
+
+use Moose;
+use Bio::SeqIO;
+use Bio::Roary::Exceptions;
+
+has 'fasta_file' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'sequence_lengths' => ( is => 'ro', isa => 'HashRef', lazy => 1, builder => '_build_sequence_lengths' );
+has '_input_seqio' => ( is => 'ro', isa => 'Bio::SeqIO', lazy => 1, builder => '_build__input_seqio' );
+
+sub _build__input_seqio {
+ my ($self) = @_;
+ return Bio::SeqIO->new( -file => $self->fasta_file, -format => 'Fasta' );
+}
+
+sub _build_sequence_lengths {
+ my ($self) = @_;
+
+ my %sequence_lengths;
+ while ( my $input_seq = $self->_input_seqio->next_seq() ) {
+ $sequence_lengths{ $input_seq->display_id } = $input_seq->length();
+ }
+ return \%sequence_lengths;
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/SortFasta.pm b/lib/Bio/Roary/SortFasta.pm
new file mode 100644
index 0000000..85ed0e4
--- /dev/null
+++ b/lib/Bio/Roary/SortFasta.pm
@@ -0,0 +1,127 @@
+package Bio::Roary::SortFasta;
+
+# ABSTRACT: sort a fasta file by name
+
+=head1 SYNOPSIS
+
+sort a fasta file by name
+ use Bio::Roary::SortFasta;
+
+ my $obj = Bio::Roary::SortFasta->new(
+ input_filename => 'infasta.fa',
+ );
+ $obj->sort_fasta->replace_input_with_output_file;
+
+=cut
+
+use Moose;
+use File::Copy;
+use Bio::SeqIO;
+
+has 'input_filename' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'output_filename' => ( is => 'ro', isa => 'Str', lazy => 1, builder => '_build_output_filename' );
+has 'make_multiple_of_three' => ( is => 'ro', isa => 'Bool', default => 0 );
+has 'remove_nnn_from_end' => ( is => 'ro', isa => 'Bool', default => 0 );
+has 'similarity' => ( is => 'rw', isa => 'Num', default => 1 );
+has 'sequences_unaligned' => ( is => 'rw', isa => 'Bool', default => 0 );
+
+has '_input_seqio' => ( is => 'ro', isa => 'Bio::SeqIO', lazy => 1, builder => '_build__input_seqio' );
+has '_output_seqio' => ( is => 'ro', isa => 'Bio::SeqIO', lazy => 1, builder => '_build__output_seqio' );
+
+sub _build_output_filename {
+ my ($self) = @_;
+ return $self->input_filename . ".sorted.fa";
+}
+
+sub _build__input_seqio {
+ my ($self) = @_;
+ return Bio::SeqIO->new( -file => $self->input_filename, -format => 'Fasta' );
+}
+
+sub _build__output_seqio {
+ my ($self) = @_;
+ return Bio::SeqIO->new( -file => ">" . $self->output_filename, -format => 'Fasta' );
+}
+
+sub _add_padding_to_make_sequence_length_multiple_of_three {
+ my ( $self, $input_seq ) = @_;
+
+ my $seq_length = $input_seq->length();
+ if ( $seq_length % 3 == 1 ) {
+ $input_seq->seq( $input_seq->seq() . "NN" );
+ }
+ elsif ( $seq_length % 3 == 2 ) {
+ $input_seq->seq( $input_seq->seq() . "N" );
+ }
+
+ return $input_seq;
+}
+
+sub _remove_nnn_from_all_sequences {
+ my ( $self, $input_sequences ) = @_;
+
+ for my $sequence_name ( sort keys %{$input_sequences} ) {
+ my $sequence = $input_sequences->{$sequence_name}->seq();
+ $sequence =~ s/NNN$//i;
+ $input_sequences->{$sequence_name}->seq($sequence);
+ }
+ return $input_sequences;
+}
+
+sub sort_fasta {
+ my ($self) = @_;
+
+ my %input_sequences;
+
+ my $nnn_at_end_of_all_sequences = 1;
+ my $sequence;
+ my $variation_detected = 0;
+ while ( my $input_seq = $self->_input_seqio->next_seq() ) {
+ $sequence = $input_seq->seq if(!defined($sequence));
+ $self->_add_padding_to_make_sequence_length_multiple_of_three($input_seq) if ( $self->make_multiple_of_three );
+ $nnn_at_end_of_all_sequences = 0 if ( $nnn_at_end_of_all_sequences == 1 && !( $input_seq->seq() =~ /NNN$/i ) );
+ $input_sequences{ $input_seq->display_id } = $input_seq;
+
+ my $factor = $self->_percentage_similarity($sequence, $input_seq->seq);
+ if($factor < $self->similarity)
+ {
+ $self->similarity($factor);
+ }
+ }
+
+ $self->_remove_nnn_from_all_sequences( \%input_sequences ) if ( $self->remove_nnn_from_end && $nnn_at_end_of_all_sequences );
+
+ my $sequence_length = 0;
+ my $sequences_unaligned = 0;
+ for my $sequence_name ( sort keys %input_sequences ) {
+ $sequence_length = $input_sequences{$sequence_name}->length if($sequence_length == 0);
+ $self->sequences_unaligned(1) if($input_sequences{$sequence_name}->length != $sequence_length);
+ $self->_output_seqio->write_seq( $input_sequences{$sequence_name} );
+ }
+ return $self;
+}
+
+sub replace_input_with_output_file {
+ my ($self) = @_;
+ move( $self->output_filename, $self->input_filename );
+ return $self;
+}
+
+sub _percentage_similarity
+{
+ my ($self, $string1, $string2) = @_;
+ my $num_differences = 0;
+ my $string1_length = length($string1);
+ for(my $i = 0; $i < $string1_length && $i< length($string2); $i++)
+ {
+ $num_differences++ if( substr($string1, $i, 1) ne substr($string2, $i, 1));
+ }
+ return 1 if($num_differences == 0);
+ return 0 if($string1_length == 0);
+ return (1.0 - ($num_differences/$string1_length));
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+
+1;
diff --git a/lib/Bio/Roary/SplitGroups.pm b/lib/Bio/Roary/SplitGroups.pm
new file mode 100644
index 0000000..0c2a991
--- /dev/null
+++ b/lib/Bio/Roary/SplitGroups.pm
@@ -0,0 +1,324 @@
+package Bio::Roary::SplitGroups;
+
+# ABSTRACT:
+
+=head1 SYNOPSIS
+
+ use Bio::Roary::SplitGroups;
+
+=cut
+
+use Moose;
+use Bio::Roary::AnalyseGroups;
+use File::Path qw(make_path remove_tree);
+use File::Copy qw(move);
+use File::Temp;
+use File::Basename;
+use File::Slurper 'read_lines';
+use Cwd;
+
+
+has 'groupfile' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'fasta_files' => ( is => 'ro', isa => 'ArrayRef', required => 1 );
+has 'outfile' => ( is => 'ro', isa => 'Str', required => 1 );
+has 'iterations' => ( is => 'ro', isa => 'Int', default => 5 );
+has 'dont_delete' => ( is => 'ro', isa => 'Bool', default => 0 );
+
+has '_neighbourhood_size' => ( is => 'ro', isa => 'Int', default => 5 );
+
+has '_group_filelist' => ( is => 'rw', isa => 'ArrayRef', lazy_build => 1 );
+has '_tmp_dir_object' => ( is => 'ro', isa => 'File::Temp::Dir', default => sub { File::Temp->newdir( DIR => getcwd, CLEANUP => 1 ); } );
+has '_tmp_dir' => ( is => 'ro', isa => 'Str', lazy => 1, builder => '_build__tmp_dir' );
+
+has '_analyse_groups_obj' => ( is => 'ro', lazy_build => 1 );
+has '_genes_to_files' => ( is => 'ro', lazy_build => 1 );
+has '_genes_to_groups' => ( is => 'rw', isa => 'HashRef' );
+
+has '_first_gene_of_group_which_doesnt_have_paralogs' => ( is => 'rw', isa => 'HashRef', default => sub {{}} );
+
+has '_genes_to_neighbourhood' => ( is => 'rw', isa => 'HashRef', lazy => 1, builder => '_build__genes_to_neighbourhood' );
+
+
+has '_gene_files_temp_dir_obj' =>
+ ( is => 'ro', isa => 'File::Temp::Dir', default => sub { File::Temp->newdir( DIR => getcwd, CLEANUP => 1 ); } );
+
+
+has '_do_sorting' => ( is => 'rw', isa => 'Bool', default => 0 ); # set to 1 for testing only
+
+sub _build__tmp_dir {
+ my ($self) = @_;
+ return $self->_tmp_dir_object->dirname();
+}
+
+sub _build__analyse_groups_obj {
+ my ( $self ) = @_;
+
+ return Bio::Roary::AnalyseGroups->new(
+ fasta_files => $self->fasta_files,
+ groups_filename => $self->groupfile
+ );
+}
+
+sub _build__genes_to_files {
+ my ( $self ) = @_;
+ return $self->_analyse_groups_obj->_genes_to_file;
+}
+
+sub _build__group_filelist {
+ my ( $self ) = @_;
+ my $tmp = $self->_tmp_dir;
+
+ my @filelist = ( $self->groupfile );
+ for my $i ( 1..($self->iterations - 1) ){
+ push( @filelist, "$tmp/group_$i" );
+ }
+ push( @filelist, $self->outfile );
+
+ return \@filelist;
+}
+
+sub _build__genes_to_neighbourhood
+{
+ my ( $self ) = @_;
+ my %genes_to_neighbourhood;
+ for my $fasta_file( @{$self->fasta_files})
+ {
+ my ( $filename, $directories, $suffix ) = fileparse( $fasta_file, qr/\.[^.]*/ );
+ system('grep \> '.$fasta_file.'| sed \'s/>//\' >'.$self->_gene_files_temp_dir_obj."/".$filename.$suffix ) ;
+
+ my @genes = read_lines($self->_gene_files_temp_dir_obj."/".$filename.$suffix );
+
+ for(my $i =0; $i< @genes; $i++)
+ {
+ for(my $offset = 1; $offset <= $self->_neighbourhood_size; $offset++)
+ {
+ if($i -$offset >= 0)
+ {
+ push(@{$genes_to_neighbourhood{$genes[$i]}}, $genes[$i - $offset ]);
+ }
+ if($i +$offset <@genes)
+ {
+ push(@{$genes_to_neighbourhood{$genes[$i]}}, $genes[$i + $offset ]);
+ }
+ }
+ }
+ }
+ return \%genes_to_neighbourhood;
+}
+
+sub split_groups {
+ my ( $self ) = @_;
+
+ # iteratively
+ for my $x ( 0..($self->iterations - 1) ){
+ my ( $in_groups, $out_groups ) = $self->_get_files_for_iteration( $x );
+
+ # read in groups, check paralogs and split
+ my @newgroups;
+ my $any_paralogs = 0;
+ $self->_set_genes_to_groups( $in_groups );
+ open( my $group_handle, '<', $in_groups );
+ while( my $line = <$group_handle> ){
+ my @group = split( /\s+/, $line );
+
+ if($self->_first_gene_of_group_which_doesnt_have_paralogs->{$group[0]})
+ {
+ push( @newgroups, \@group );
+ }
+ elsif(@group == 1)
+ {
+ $self->_first_gene_of_group_which_doesnt_have_paralogs->{$group[0]}++;
+ push( @newgroups, \@group );
+ }
+ elsif( $self->_contains_paralogs( \@group ) ){
+ my @true_orthologs = @{ $self->_true_orthologs( \@group ) };
+ push( @newgroups, @true_orthologs);
+ $any_paralogs = 1;
+ }
+ else {
+ $self->_first_gene_of_group_which_doesnt_have_paralogs->{$group[0]}++;
+ push( @newgroups, \@group );
+ }
+ }
+ close( $group_handle );
+
+ # check if next iteration required, move output if not
+ unless ($any_paralogs){
+ move $in_groups, $self->outfile; # input file will be the same as new output file if no splitting has been performed
+ last;
+ }
+
+ # write split groups to file
+ open( my $outfile_handle, '>', $out_groups );
+ for my $g ( @newgroups ) {
+ my $group_str = join( "\t", @{ $g } ) . "\n";
+ print $outfile_handle $group_str;
+ }
+ close( $outfile_handle );
+ }
+}
+
+sub _set_genes_to_groups {
+ my ( $self, $groupfile ) = @_;
+
+ my %genes2groups;
+ my $c = 0;
+ open( my $gfh, '<', $groupfile );
+ while( my $line = <$gfh> ){
+ chomp $line;
+ my @genes = split( /\s+/, $line );
+ for my $g ( @genes ){
+ $genes2groups{$g} = $c;
+ }
+ $c++;
+ }
+ close($gfh);
+ $self->_genes_to_groups( \%genes2groups );
+}
+
+sub _update_genes_to_groups {
+ my ( $self, $groups ) = @_;
+
+ my %genes2groups = %{ $self->_genes_to_groups };
+ my $c = 1;
+ for my $g ( @{ $groups } ){
+ for my $h ( @{ $g } ){
+ $genes2groups{$h} .= ".$c";
+ }
+ $c++;
+ }
+
+ $self->_genes_to_groups( \%genes2groups );
+}
+
+sub _get_files_for_iteration {
+ my ( $self, $n ) = @_;
+ my @filelist = @{ $self->_group_filelist };
+ return ( $filelist[$n], $filelist[$n+1] );
+}
+
+sub _contains_paralogs {
+ my ( $self, $group ) = @_;
+
+ return 1 if defined $self->_find_paralogs( $group );
+ return 0;
+}
+
+sub _find_paralogs {
+ my ( $self, $group ) = @_;
+
+ my %occ;
+ for my $gene ( @{ $group } ){
+ my $gene_file = $self->_genes_to_files->{ $gene };
+ push( @{ $occ{$gene_file} }, $gene );
+ }
+
+ # pick the smallest number of paralogs
+ my $smallest_number = 1000000;
+ my $smallest_group;
+ for my $v ( values %occ ){
+ my $v_len = scalar( @{$v} );
+ if ( $v_len < $smallest_number && $v_len > 1 ){
+ $smallest_number = $v_len;
+ $smallest_group = $v;
+ }
+ }
+ return $smallest_group if ( defined $smallest_group );
+
+ return undef;
+}
+
+sub _true_orthologs {
+ my ( $self, $group ) = @_;
+
+ # first, create CGN hash for group
+ my %cgns;
+ for my $g ( @{ $group } ){
+ $cgns{$g} = $self->_parse_gene_neighbourhood( $g );
+ }
+
+ # finding paralogs in the group
+ my @paralogs = @{ $self->_find_paralogs( $group ) };
+ my @paralog_cgns_groups;
+ for my $p ( @paralogs ){
+ my %paralog_groups ;
+ for my $paralog_gene (@{$cgns{$p}})
+ {
+ my $gene_paralog_group = $self->_genes_to_groups->{$paralog_gene};
+ next unless( defined($gene_paralog_group));
+ $paralog_groups{$self->_genes_to_groups->{$paralog_gene}}++;
+ }
+ push( @paralog_cgns_groups, \%paralog_groups );
+ }
+
+ # create data structure to hold new groups
+ my @new_groups;
+ for my $p ( @paralogs ){
+ push( @new_groups, [ $p ] );
+ }
+ push( @new_groups, [] ); # extra "leftovers" array to gather genes that don't share CGN with anything
+
+ # cluster other members of the group to their closest match
+ for my $g ( @{ $group } ){
+ next if ( grep {$_ eq $g} @paralogs );
+ my $closest = $self->_closest_cgn( $cgns{$g}, \@paralog_cgns_groups );
+ push( @{ $new_groups[$closest] }, $g );
+ }
+
+ # check for "leftovers", remove if absent
+ my $last = pop @new_groups;
+ push( @new_groups, $last ) if ( @$last > 0 );
+
+ # sort
+ if ( $self->_do_sorting ){
+ my @sorted_new_groups;
+ for my $gr ( @new_groups ){
+ my @s_gr = sort @{ $gr };
+ push( @sorted_new_groups, \@s_gr );
+ }
+ return \@sorted_new_groups;
+ }
+
+ return \@new_groups;
+}
+
+sub _closest_cgn {
+ my ( $self, $cgn, $p_cgns ) = @_;
+
+ my @paralog_cgns = @{ $p_cgns };
+ my $best_score = 0;
+ my $bs_index = -1; # return -1 to add to "leftovers" array if no better score is found
+ for my $i ( 0..$#paralog_cgns ){
+ my $p_cgn = $paralog_cgns[$i];
+ my $score = $self->_shared_cgn_score( $cgn, $p_cgn );
+ if ( $score > $best_score ){
+ $best_score = $score;
+ $bs_index = $i;
+ }
+ }
+ return $bs_index;
+}
+
+sub _shared_cgn_score {
+ my ( $self, $cgn1, $cgn2 ) = @_;
+
+ my $total_shared = 0;
+ for my $i ( @{ $cgn1 } ){
+ my $input_group = $self->_genes_to_groups->{$i};
+ next unless(defined($input_group));
+ $total_shared++ if($cgn2->{$input_group});
+ }
+ my $score = $total_shared/scalar @{ $cgn1 };
+ return $score;
+}
+
+sub _parse_gene_neighbourhood {
+ my ( $self, $gene_id ) = @_;
+
+ return $self->_genes_to_neighbourhood->{$gene_id };
+
+}
+
+no Moose;
+__PACKAGE__->meta->make_immutable;
+1;
\ No newline at end of file
diff --git a/lib/Bio/Roary/SpreadsheetRole.pm b/lib/Bio/Roary/SpreadsheetRole.pm
new file mode 100644
index 0000000..467f47a
--- /dev/null
+++ b/lib/Bio/Roary/SpreadsheetRole.pm
@@ -0,0 +1,66 @@
+package Bio::Roary::SpreadsheetRole;
+
+# ABSTRACT: Read and write a spreadsheet
+
+=head1 SYNOPSIS
+
+with 'Bio::Roary::SpreadsheetRole';
+
+=cut
+use Moose::Role;
+
+has 'spreadsheet' => ( is => 'ro', isa => 'Str', required => 1 );
+has '_fixed_headers' => ( is => 'ro', isa => 'ArrayRef', lazy => 1, builder => '_build__fixed_headers' );
+has '_input_spreadsheet_fh' => ( is => 'ro', lazy => 1, builder => '_build__input_spreadsheet_fh' );
+has '_output_spreadsheet_fh' => ( is => 'ro', lazy => 1, builder => '_build__output_spreadsheet_fh' );
+has '_fixed_headers' => ( is => 'ro', isa => 'ArrayRef', lazy => 1, builder => '_build__fixed_headers' );
+has '_num_fixed_headers' => ( is => 'ro', isa => 'Int', lazy => 1, builder => '_build__num_fixed_headers' );
+has '_csv_parser' => ( is => 'ro', isa => 'Text::CSV',lazy => 1, builder => '_build__csv_parser' );
+has '_csv_output' => ( is => 'ro', isa => 'Text::CSV',lazy => 1, builder => '_build__csv_output' );
+
+sub BUILD
+{
+ my ($self) = @_;
+ $self->_input_spreadsheet_fh;
+}
+
+sub _build__fixed_headers
+{
+ my ($self) = @_;
+ my @fixed_headers = @{Bio::Roary::GroupStatistics->fixed_headers()};
+ return \@fixed_headers;
+}
+
+sub _build__csv_parser
+{
+ my ($self) = @_;
+ return Text::CSV->new( { binary => 1, always_quote => 1} );
+}
+
+sub _build__csv_output
+{
+ my ($self) = @_;
+ return Text::CSV->new( { binary => 1, always_quote => 1, eol => "\r\n"} );
+}
+
+sub _build__input_spreadsheet_fh {
+ my ($self) = @_;
+ open( my $fh, $self->spreadsheet ) or die "Couldnt open input spreadsheet: ".$self->spreadsheet ;
+ return $fh;
+}
+
+sub _build__output_spreadsheet_fh {
+ my ($self) = @_;
+ open( my $fh, '>', $self->output_filename );
+ return $fh;
+}
+
+sub _build__num_fixed_headers
+{
+ my ($self) = @_;
+ return @{$self->_fixed_headers};
+}
+
+
+
+1;
diff --git a/t/00_requires_external.t b/t/00_requires_external.t
new file mode 100755
index 0000000..b668039
--- /dev/null
+++ b/t/00_requires_external.t
@@ -0,0 +1,20 @@
+#!/usr/bin/env perl
+
+use Test::Most;
+use FindBin;
+plan tests => 8;
+bail_on_fail if 0;
+use Env::Path 'PATH';
+
+
+my $OPSYS = $^O;
+my $BINDIR = "$FindBin::RealBin/../binaries/$OPSYS";
+
+for my $dir ($BINDIR, $FindBin::RealBin) {
+ if (-d $dir) {
+ $ENV{PATH} .= ":$dir";
+ }
+}
+
+ok(scalar PATH->Whence($_), "$_ in PATH") for qw(blastp makeblastdb mcl mcxdeblast bedtools prank parallel mafft);
+
diff --git a/t/Bio/Roary/AccessoryBinaryFasta.t b/t/Bio/Roary/AccessoryBinaryFasta.t
new file mode 100755
index 0000000..435839b
--- /dev/null
+++ b/t/Bio/Roary/AccessoryBinaryFasta.t
@@ -0,0 +1,72 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use Test::Files;
+
+BEGIN { unshift( @INC, './lib' ) }
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::AccessoryBinaryFasta');
+}
+
+my $dummy_annotate_groups = Bio::Roary::AnnotateGroups->new(
+ gff_files => ['t/data/query_1.gff','t/data/query_2.gff','t/data/query_3.gff'],
+ groups_filename => 't/data/query_groups',
+);
+
+my $dummy_analyse_groups = Bio::Roary::AnalyseGroups->new(
+ fasta_files => ['t/data/query_1.fa','t/data/query_2.fa','t/data/query_3.fa'],
+ groups_filename => 't/data/query_groups'
+);
+
+
+
+ok(
+ my $obj = Bio::Roary::AccessoryBinaryFasta->new(
+ input_files => [ 't/abc/aaa', 't/abc/bbb', 't/abc/ccc', 't/abc/ddd' ],
+ groups_to_files =>
+ {
+ group_1 => { 't/abc/aaa' => [1] },
+ group_2 => { 't/abc/aaa' => [1], 't/abc/bbb' => [2] },
+ group_3 => { 't/abc/aaa' => [1], 't/abc/bbb' => [2], 't/abc/ccc' => [3] },
+ group_4 => { 't/abc/aaa' => [1], 't/abc/bbb' => [2], 't/abc/ccc' => [3], 't/abc/ddd' => [4] },
+ },
+ _lower_bound_value => 0,
+ _upper_bound_value => 4,
+ annotate_groups_obj => $dummy_annotate_groups,
+ analyse_groups_obj => $dummy_analyse_groups
+ ),
+ 'initialise accessory binary fasta file'
+);
+
+ok( $obj->create_accessory_binary_fasta(), 'create output file' );
+
+compare_ok( 'accessory_binary_genes.fa', 't/data/expected_accessory_binary_genes.fa','binary accessory fasta file created');
+
+
+ok(
+ $obj = Bio::Roary::AccessoryBinaryFasta->new(
+ input_files => [ 'aaa', 'bbb', 'ccc', 'ddd' ],
+ groups_to_files =>
+ {
+ group_1 => { 'aaa' => [1] },
+ group_2 => { 'aaa' => [1], 'bbb' => [2] },
+ group_3 => { 'aaa' => [1], 'bbb' => [2], 'ccc' => [3] },
+ group_4 => { 'aaa' => [1], 'bbb' => [2], 'ccc' => [3], 'ddd' => [4] },
+ },
+ annotate_groups_obj => $dummy_annotate_groups,
+ analyse_groups_obj => $dummy_analyse_groups
+ ),
+ 'initialise accessory binary fasta file bounded'
+);
+
+is($obj->_lower_bound_value, 1, 'lower bound value');
+is($obj->_upper_bound_value, 3, 'upper bound value');
+ok( $obj->create_accessory_binary_fasta(), 'create output file bounded' );
+
+compare_ok( 'accessory_binary_genes.fa', 't/data/expected_accessory_binary_genes_bounded.fa','binary accessory fasta file created bounded');
+
+
+done_testing();
diff --git a/t/Bio/Roary/AccessoryClustering.t b/t/Bio/Roary/AccessoryClustering.t
new file mode 100755
index 0000000..c9a3333
--- /dev/null
+++ b/t/Bio/Roary/AccessoryClustering.t
@@ -0,0 +1,104 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+
+BEGIN { unshift( @INC, './lib' ) }
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::AccessoryClustering');
+}
+
+my $identity_to_num_clusters = {
+ '1' => [ 10, 10 ],
+ '0.99' => [ 4, 5 ],
+ '0.95' => [ 2, 4 ],
+ '0.90' => [ 1, 1 ],
+};
+
+for my $percentage_identity ( keys %{$identity_to_num_clusters} ) {
+ ok(
+ my $obj = Bio::Roary::AccessoryClustering->new(
+ input_file => 't/data/input_accessory_binary.fa',
+ identity => $percentage_identity
+ ),
+ "initialise object with identity of $percentage_identity"
+ );
+ ok( my @clusters = keys %{ $obj->clusters_to_samples }, "build the clusters for $percentage_identity" );
+ ok( $obj->sample_weights, "build samples weights for $percentage_identity" );
+ ok( $obj->samples_to_clusters, "build samples to clusters for $percentage_identity" );
+
+ my $min_cluster_size = $identity_to_num_clusters->{$percentage_identity}->[0];
+ my $max_cluster_size = $identity_to_num_clusters->{$percentage_identity}->[1];
+ ok(
+ ( @clusters >= $min_cluster_size && @clusters <= $max_cluster_size ? 1 : 0 ),
+ "check number of clusters as expected, allowing for some variation for $percentage_identity"
+ );
+}
+
+my $obj = Bio::Roary::AccessoryClustering->new(
+ input_file => 't/data/input_accessory_binary.fa',
+ identity => 0.9
+);
+is_deeply(
+ $obj->samples_to_clusters,
+ {
+ 'seq6' => 'seq1',
+ 'seq3' => 'seq1',
+ 'seq7' => 'seq1',
+ 'seq9' => 'seq1',
+ 'seq10' => 'seq1',
+ 'seq2' => 'seq1',
+ 'seq8' => 'seq1',
+ 'seq1' => 'seq1',
+ 'seq4' => 'seq1',
+ 'seq5' => 'seq1'
+ },
+ 'samples to clusters'
+);
+my @sample_weights = values %{ $obj->sample_weights };
+is_deeply( \@sample_weights, [ 0.1, 0.1, 0.1, 0.1, 0.1, 0.1, 0.1, 0.1, 0.1, 0.1 ], 'sample weights' );
+
+$obj = Bio::Roary::AccessoryClustering->new(
+ input_file => 't/data/input_accessory_binary.fa',
+ identity => 1
+);
+
+is_deeply(
+ $obj->samples_to_clusters,
+ {
+ 'seq6' => 'seq6',
+ 'seq3' => 'seq3',
+ 'seq7' => 'seq7',
+ 'seq9' => 'seq9',
+ 'seq10' => 'seq10',
+ 'seq2' => 'seq2',
+ 'seq8' => 'seq8',
+ 'seq1' => 'seq1',
+ 'seq4' => 'seq4',
+ 'seq5' => 'seq5'
+ },
+ 'samples to clusters'
+);
+ at sample_weights = values %{ $obj->sample_weights };
+is_deeply( \@sample_weights, [ 1, 1, 1, 1, 1, 1, 1, 1, 1, 1 ], 'sample weights' );
+
+
+
+$obj = Bio::Roary::AccessoryClustering->new(
+ input_file => 't/data/large_accessory_binary_genes.fa'
+);
+
+ok( my @clusters = keys %{ $obj->clusters_to_samples }, "build the clusters for large_accessory_binary_genes.fa" );
+ok( $obj->sample_weights, "build samples weights for large_accessory_binary_genes.fa" );
+ok( $obj->samples_to_clusters, "build samples to clusters for large_accessory_binary_genes.fa" );
+
+ok(
+ ( @clusters >= 6 && @clusters <= 14 ? 1 : 0 ),
+ "check number of clusters as expected, allowing for some variation for large_accessory_binary_genes.fa"
+);
+
+unlink('_accessory_clusters');
+unlink('_accessory_clusters.clstr');
+done_testing();
diff --git a/t/Bio/Roary/AnalyseGroups.t b/t/Bio/Roary/AnalyseGroups.t
new file mode 100644
index 0000000..051a3e3
--- /dev/null
+++ b/t/Bio/Roary/AnalyseGroups.t
@@ -0,0 +1,70 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+
+BEGIN { unshift( @INC, './lib' ) }
+$ENV{PATH} .= ":./bin";
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::AnalyseGroups');
+}
+
+ok(
+ my $plot_groups_obj = Bio::Roary::AnalyseGroups->new(
+ fasta_files => [ 't/data/example_1.faa', 't/data/example_2.faa' ],
+ groups_filename => 't/data/example_groups'
+ ),
+ 'initialise with two fasta files'
+);
+
+is( $plot_groups_obj->_number_of_isolates, 2, 'Number of isolates' );
+
+is_deeply(
+ $plot_groups_obj->_genes_to_file,
+ {
+ '1234#10_00003' => 't/data/example_1.faa',
+ '1234#10_00017' => 't/data/example_2.faa',
+ '1234#10_00001' => 't/data/example_1.faa',
+ '1234#10_00016' => 't/data/example_2.faa',
+ '1234#10_00007' => 't/data/example_1.faa',
+ '1234#10_00006' => 't/data/example_1.faa',
+ '1234#10_00018' => 't/data/example_2.faa',
+ '1234#10_00005' => 't/data/example_1.faa',
+ '1234#10_00002' => 't/data/example_1.faa'
+ },
+ 'genes map to the correct files'
+);
+
+
+is_deeply(
+ $plot_groups_obj->_groups_to_genes,
+ {
+ 'group_3' => [ '1234#10_00005', '1234#10_00005' ],
+ 'group_5' => [ '1234#10_00016' ],
+ 'group_4' => [ '1234#10_00006', '1234#10_00007' ],
+ 'group_6' => [ '1234#10_00017' ],
+ 'group_1' => [ '1234#10_00001', '1234#10_00002' ],
+ 'group_2' => [ '1234#10_00003', '1234#10_00018', '1234#10_00005' ]
+ },
+ 'Groups to genes hash'
+);
+
+is_deeply(
+ $plot_groups_obj->_genes_to_groups,
+ {
+ '1234#10_00003' => 'group_2',
+ '1234#10_00017' => 'group_6',
+ '1234#10_00001' => 'group_1',
+ '1234#10_00016' => 'group_5',
+ '1234#10_00007' => 'group_4',
+ '1234#10_00006' => 'group_4',
+ '1234#10_00018' => 'group_2',
+ '1234#10_00005' => 'group_3',
+ '1234#10_00002' => 'group_1'
+ },
+ 'genes to groups hash'
+);
+
+done_testing();
diff --git a/t/Bio/Roary/AnnotateGroups.t b/t/Bio/Roary/AnnotateGroups.t
new file mode 100755
index 0000000..8b205da
--- /dev/null
+++ b/t/Bio/Roary/AnnotateGroups.t
@@ -0,0 +1,102 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use Moose;
+BEGIN { unshift( @INC, './t/lib' ) }
+with 'TestHelper';
+
+BEGIN { unshift( @INC, './lib' ) }
+$ENV{PATH} .= ":./bin";
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::AnnotateGroups');
+}
+
+my $obj;
+
+ok(
+ $obj = Bio::Roary::AnnotateGroups->new(
+ gff_files => [ 't/data/query_1.gff', 't/data/query_2.gff', 't/data/query_3.gff' ],
+ groups_filename => 't/data/query_groups',
+ ),
+ 'initalise'
+);
+
+ok( $obj->reannotate, 'reannotate' );
+is_deeply(
+ $obj->_ids_to_gene_size,
+ {
+ 'abc_00012' => 188,
+ '2_3' => 1001,
+ '1_1' => 959,
+ 'abc_00004' => 716,
+ '3_3' => 1001,
+ '3_2' => 725,
+ '2_2' => 725,
+ 'abc_00006' => 725,
+ 'abc_00008' => 935,
+ '1_6' => 134,
+ 'abc_00015' => 134,
+ '3_1' => 959,
+ 'abc_00014' => 134,
+ 'abc_01705' => 1556,
+ 'abc_00013' => 75,
+ 'abc_00010' => 227,
+ '1_2' => 725,
+ 'abc_00011' => 947,
+ 'abc_00016' => 686,
+ '2_7' => 134,
+ '1_3' => 1001,
+ '2_1' => 959,
+ '3_5' => 686,
+ 'abc_00002' => 146,
+ 'abc_00003' => 197
+ },
+ 'gene lengths as expected'
+);
+
+is_deeply(
+ $obj->group_nucleotide_lengths,
+ {
+ 'group_3' => {
+ 'average' => 1001,
+ 'min' => 1001,
+ 'max' => 1001
+ },
+ 'group_5' => {
+ 'average' => 686,
+ 'min' => 686,
+ 'max' => 686
+ },
+ 'group_7' => {
+ 'average' => 134,
+ 'min' => 134,
+ 'max' => 134
+ },
+ 'group_1' => {
+ 'average' => 959,
+ 'min' => 959,
+ 'max' => 959
+ },
+ 'group_6' => {
+ 'average' => 134,
+ 'min' => 134,
+ 'max' => 134
+ },
+ 'group_2' => {
+ 'average' => 725,
+ 'min' => 725,
+ 'max' => 725
+ }
+ },
+ 'group lengths'
+);
+
+compare_files( 'reannotated_groups_file', 't/data/expected_reannotated_groups_file', 'groups reannotated as expected' );
+
+unlink('reannotated_groups_file');
+
+done_testing();
+
diff --git a/t/Bio/Roary/AssemblyStatistics.t b/t/Bio/Roary/AssemblyStatistics.t
new file mode 100644
index 0000000..0bd8925
--- /dev/null
+++ b/t/Bio/Roary/AssemblyStatistics.t
@@ -0,0 +1,121 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use Test::Files;
+
+BEGIN { unshift( @INC, './lib' ) }
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::AssemblyStatistics');
+}
+
+my $obj;
+ok( $obj = Bio::Roary::AssemblyStatistics->new( spreadsheet => 't/data/input_block_spreadsheet.csv' ), 'initialise spreadsheet' );
+
+my @genes = sort keys %{ $obj->_genes_to_rows };
+is_deeply(
+ \@genes,
+ [
+ 'SBOV29371', 'SBOV38871', 'SBOV43201', 'STY3593', 'STY4162', 'bcsC_1', 'betC_2', 'comM_2',
+ 'dmsA4_1', 'dosC', 'dsbA_3', 'fadH_1', 'fimD_3', 'fliB_2', 'fliF', 'ftsN',
+ 'gatY_1', 'glfT2', 'group_1000', 'group_1001', 'group_1004', 'group_1006', 'group_1009', 'group_220',
+ 'group_277', 'group_281', 'group_283', 'group_284', 'group_288', 'hemD', 'hsrA_2', 'icsA',
+ 'kdpD', 'ligB_1', 'marT_1', 'nepI', 'rffH', 'rpoS', 'selA_1', 'speC_3',
+ 'sptP', 'srgB', 'stp', 'tmcA', 'tub', 'yadA', 'ybbW_1', 'yhaO_2',
+ 'yicJ_1', 'yigZ'
+ ],
+ 'all gene rows available'
+);
+
+is_deeply(
+ $obj->ordered_genes,
+ [
+ 'dmsA4_1', 'group_1000', 'group_1001', 'SBOV43201', 'dosC', 'stp', 'fliB_2', 'fliF',
+ 'dsbA_3', 'srgB', 'fimD_3', 'betC_2', 'tmcA', 'tub', 'rffH', 'hemD',
+ 'group_1006', 'STY3593', 'group_1004', 'yigZ', 'group_220', 'glfT2', 'kdpD', 'speC_3',
+ 'ybbW_1', 'sptP', 'SBOV29371', 'rpoS', 'fadH_1', 'yhaO_2', 'bcsC_1', 'STY4162',
+ 'yadA', 'ligB_1', 'icsA', 'marT_1', 'selA_1', 'nepI', 'gatY_1', 'SBOV38871',
+ 'group_288', 'hsrA_2', 'group_281', 'group_283', 'group_284', 'yicJ_1', 'ftsN', 'group_277',
+ 'group_1009', 'comM_2'
+ ],
+ 'ordered genes'
+);
+
+is_deeply(
+ $obj->sample_names_to_column_index,
+ {
+ 'threeblocks' => 18,
+ 'nocontigs' => 17,
+ 'contigwithgaps' => 16,
+ 'oneblock' => 14,
+ 'threeblocksinversion' => 19,
+ 'oneblockrev' => 15
+ },
+ 'sample names to column index'
+);
+
+is_deeply( $obj->_sample_statistics('oneblock'), { num_blocks => 1, largest_block_size => 50 }, 'one block' );
+is_deeply( $obj->_sample_statistics('oneblockrev'), { num_blocks => 1, largest_block_size => 50 }, 'one block reversed' );
+is_deeply(
+ $obj->_sample_statistics('contigwithgaps'),
+ { num_blocks => 1, largest_block_size => 50 },
+ 'one block where there are gaps everywhere'
+);
+is_deeply( $obj->_sample_statistics('nocontigs'), { num_blocks => 50, largest_block_size => 1 }, 'no contiguous blocks' );
+is_deeply( $obj->_sample_statistics('threeblocks'), { num_blocks => 3, largest_block_size => 21 }, 'three blocks' );
+is_deeply(
+ $obj->_sample_statistics('threeblocksinversion'),
+ { num_blocks => 3, largest_block_size => 20 },
+ 'three blocks with an inversion in the middle'
+);
+is_deeply( $obj->gene_category_count, { core => 50 }, 'Gene category counts' );
+
+# t/data/gene_category_count.csv
+ok( $obj = Bio::Roary::AssemblyStatistics->new( spreadsheet => 't/data/gene_category_count.csv' ),
+ 'initialise spreadsheet with variable numbers of genes in samples' );
+is_deeply(
+ $obj->gene_category_count,
+ {
+ 'core' => 1,
+ 'cloud' => 4,
+ 'soft_core' => 1,
+ 'shell' => 24
+ },
+ 'Categories as expected'
+);
+ok($obj->create_summary_output, 'create output file');
+compare_ok('summary_statistics.txt', 't/data/expected_summary_statistics.txt', 'summary statistics as expected');
+
+
+# t/data/gene_category_count.csv
+ok( $obj = Bio::Roary::AssemblyStatistics->new( spreadsheet => 't/data/gene_category_count.csv', core_definition => 0.9667 ),
+ 'initialise spreadsheet with core of 96.67%' );
+is_deeply(
+ $obj->gene_category_count,
+ {
+ 'core' => 1,
+ 'soft_core' => 1,
+ 'cloud' => 4,
+ 'shell' => 24
+ },
+ 'Categories as expected with cd of 96.67%'
+);
+
+# t/data/gene_category_count.csv
+ok( $obj = Bio::Roary::AssemblyStatistics->new( spreadsheet => 't/data/gene_category_count.csv', core_definition => 0.9666 ),
+ 'initialise spreadsheet with core of 96.66%' );
+is_deeply(
+ $obj->gene_category_count,
+ {
+ 'core' => 2,
+ 'cloud' => 4,
+ 'shell' => 24
+ },
+ 'Categories as expected with cd of 96.66%'
+);
+
+
+unlink('summary_statistics.txt');
+done_testing();
diff --git a/t/Bio/Roary/ChunkFastaFile.t b/t/Bio/Roary/ChunkFastaFile.t
new file mode 100644
index 0000000..fdd4d62
--- /dev/null
+++ b/t/Bio/Roary/ChunkFastaFile.t
@@ -0,0 +1,41 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use Test::Files;
+
+BEGIN { unshift( @INC, './lib' ) }
+$ENV{PATH} .= ":./bin";
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::ChunkFastaFile');
+}
+
+my $obj;
+
+
+ok($obj = Bio::Roary::ChunkFastaFile->new(
+ fasta_file => 't/data/example_1.faa',
+),'initalise object to produce a single sequence file');
+is_deeply($obj->sequence_file_names, [$obj->_working_directory_name.'/0.seq'], 'a single sequence file is created' );
+compare_ok('t/data/example_1.faa', $obj->_working_directory_name.'/0.seq', 'input and output file should be the same');
+
+ok($obj = Bio::Roary::ChunkFastaFile->new(
+ fasta_file => 't/data/example_1.faa',
+ target_chunk_size => 1,
+),'initalise object to produce one file per sequence');
+is_deeply($obj->sequence_file_names, [
+ $obj->_working_directory_name.'/0.seq',
+$obj->_working_directory_name.'/1.seq',
+$obj->_working_directory_name.'/2.seq',
+$obj->_working_directory_name.'/3.seq',
+$obj->_working_directory_name.'/4.seq',
+$obj->_working_directory_name.'/5.seq',
+],
+'a sequence file per sequence is created' );
+compare_ok('t/data/expected_0.seq',$obj->_working_directory_name.'/0.seq', 'the first sequence file is as expected');
+compare_ok('t/data/expected_5.seq', $obj->_working_directory_name.'/5.seq', 'the last sequence file is as expected');
+
+
+done_testing();
diff --git a/t/Bio/Roary/CombinedProteome.t b/t/Bio/Roary/CombinedProteome.t
new file mode 100644
index 0000000..ccbeb40
--- /dev/null
+++ b/t/Bio/Roary/CombinedProteome.t
@@ -0,0 +1,39 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use Test::Files;
+
+BEGIN { unshift( @INC, './lib' ) }
+$ENV{PATH} .= ":./bin";
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::CombinedProteome');
+}
+
+my $obj;
+
+ok(
+ $obj = Bio::Roary::CombinedProteome->new(
+ proteome_files => [ 't/data/example_1.faa', 't/data/example_2.faa' ],
+ output_filename => 'combined_proteome.fa'
+ ),
+ 'initalise object with two files'
+);
+
+ok( $obj->create_combined_proteome_file, 'Create a combined file' );
+
+compare_ok('combined_proteome.fa',
+ 't/data/expected_combined_proteome.fa',
+ 'Combined file is as expected'
+);
+unlink('combined_proteome.fa');
+
+throws_ok{
+ Bio::Roary::CombinedProteome->new(
+ proteome_files => [ 't/data/example_1.faa', 't/data/non_existant_file.faa' ],
+ output_filename => 'combined_proteome.fa')
+ } qr /Cant open file/, 'non existant files should throw an error';
+
+done_testing();
diff --git a/t/Bio/Roary/CommandLine/ExtractProteomeFromGff.t b/t/Bio/Roary/CommandLine/ExtractProteomeFromGff.t
new file mode 100644
index 0000000..76e7472
--- /dev/null
+++ b/t/Bio/Roary/CommandLine/ExtractProteomeFromGff.t
@@ -0,0 +1,28 @@
+#!/usr/bin/env perl
+use Moose;
+use Data::Dumper;
+use Cwd;
+
+BEGIN { unshift( @INC, './lib' ) }
+BEGIN { unshift( @INC, './t/lib' ) }
+with 'TestHelper';
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::CommandLine::ExtractProteomeFromGff');
+}
+my $script_name = 'Bio::Roary::CommandLine::ExtractProteomeFromGff';
+my $cwd = getcwd();
+system('touch empty_file');
+my %scripts_and_expected_files = (
+ 't/data/example_annotation.gff' =>
+ ['example_annotation.gff.proteome.faa','t/data/example_annotation.gff.proteome.faa.expected' ],
+ '-t 1 t/data/example_annotation.gff' =>
+ ['example_annotation.gff.proteome.faa','t/data/example_annotation.gff.proteome.faa.expected' ],
+ '-h' =>
+ [ 'empty_file', 't/data/empty_file' ],
+);
+
+mock_execute_script_and_check_output( $script_name, \%scripts_and_expected_files );
+
+done_testing();
diff --git a/t/Bio/Roary/CommandLine/GeneAlignmentFromNucleotides.t b/t/Bio/Roary/CommandLine/GeneAlignmentFromNucleotides.t
new file mode 100644
index 0000000..c682c32
--- /dev/null
+++ b/t/Bio/Roary/CommandLine/GeneAlignmentFromNucleotides.t
@@ -0,0 +1,41 @@
+#!/usr/bin/env perl
+use Moose;
+use Data::Dumper;
+use Cwd;
+use File::Which;
+
+BEGIN { unshift( @INC, './lib' ) }
+BEGIN { unshift( @INC, './t/lib' ) }
+with 'TestHelper';
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::CommandLine::GeneAlignmentFromNucleotides');
+}
+
+my $script_name = 'Bio::Roary::CommandLine::GeneAlignmentFromNucleotides';
+my $cwd = getcwd();
+system('touch empty_file');
+system('cp t/data/nuc_to_be_aligned.fa t/data/f.fa');
+my %scripts_and_expected_files = (
+ 't/data/f.fa' => [ 't/data/f.fa.aln', 't/data/expected_nuc_multifasta.fa.aln' ],
+ '-h' => [ 'empty_file', 't/data/empty_file' ],
+);
+
+SKIP:
+{
+ skip "prank not installed", 2 unless ( which('prank') );
+ mock_execute_script_and_check_output( $script_name, \%scripts_and_expected_files );
+}
+
+SKIP:
+{
+ skip "mafft not installed", 2 unless ( which('mafft') );
+ system('cp t/data/nuc_to_be_aligned.fa t/data/f.fa');
+ %scripts_and_expected_files = (
+ '--mafft t/data/f.fa' => [ 't/data/f.fa.aln', 't/data/expected_nuc_multifasta_mafft.fa.aln' ],
+ );
+ mock_execute_script_and_check_output( $script_name, \%scripts_and_expected_files );
+}
+
+done_testing();
diff --git a/t/Bio/Roary/CommandLine/ParallelAllAgainstAllBlastp.t b/t/Bio/Roary/CommandLine/ParallelAllAgainstAllBlastp.t
new file mode 100644
index 0000000..73040a4
--- /dev/null
+++ b/t/Bio/Roary/CommandLine/ParallelAllAgainstAllBlastp.t
@@ -0,0 +1,29 @@
+#!/usr/bin/env perl
+use Moose;
+use Data::Dumper;
+use Cwd;
+
+BEGIN { unshift( @INC, './lib' ) }
+BEGIN { unshift( @INC, './t/lib' ) }
+with 'TestHelper';
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::CommandLine::ParallelAllAgainstAllBlastp');
+}
+my $script_name = 'Bio::Roary::CommandLine::ParallelAllAgainstAllBlastp';
+my $cwd = getcwd();
+
+system('touch empty_file');
+my %scripts_and_expected_files = (
+ '-m '.$cwd.'/t/bin/dummy_makeblastdb -b '.$cwd.'/t/bin/dummy_blastp -j Local t/data/example_1.faa' =>
+ [ 'blast_results', 't/data/empty_file' ],
+ '-o different_output_filename -m '.$cwd.'/t/bin/dummy_makeblastdb -b '.$cwd.'/t/bin/dummy_blastp -j Local t/data/example_1.faa' =>
+ [ 'different_output_filename', 't/data/empty_file' ],
+ '-h' =>
+ [ 'empty_file', 't/data/empty_file' ],
+);
+
+mock_execute_script_and_check_output( $script_name, \%scripts_and_expected_files );
+
+done_testing();
\ No newline at end of file
diff --git a/t/Bio/Roary/CommandLine/QueryRoary.t b/t/Bio/Roary/CommandLine/QueryRoary.t
new file mode 100755
index 0000000..9e83f83
--- /dev/null
+++ b/t/Bio/Roary/CommandLine/QueryRoary.t
@@ -0,0 +1,71 @@
+#!/usr/bin/env perl
+use Moose;
+use Data::Dumper;
+use Cwd;
+
+BEGIN { unshift( @INC, './lib' ) }
+BEGIN { unshift( @INC, './t/lib' ) }
+with 'TestHelper';
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::CommandLine::QueryRoary');
+}
+my $script_name = 'Bio::Roary::CommandLine::QueryRoary';
+my $cwd = getcwd();
+
+system('touch empty_file');
+system('touch empty_file2');
+
+my %scripts_and_expected_files = (
+ '-g t/data/example_groups -a gene_multifasta -n group_2 t/data/example_1.faa t/data/example_2.faa' =>
+ [ 'pan_genome_results_group_2.fa', 't/data/expected_output_groups_group_2.fa' ],
+ '-g t/data/example_groups -a gene_multifasta -n group_5 t/data/example_1.faa t/data/example_2.faa ' =>
+ [ 'pan_genome_results_group_5.fa', 't/data/expected_output_groups_group_5.fa' ],
+ '-g t/data/example_groups -a gene_multifasta -n group_2,group_5 t/data/example_1.faa t/data/example_2.faa' =>
+ [ 'pan_genome_results_group_5.fa', 't/data/expected_output_groups_group_5.fa' ],
+ '-g t/data/example_groups -a gene_multifasta -n group_5,group_2 t/data/example_1.faa t/data/example_2.faa ' =>
+ [ 'pan_genome_results_group_5.fa', 't/data/expected_output_groups_group_5.fa' ],
+ '-g t/data/example_groups -a gene_multifasta -n group_5,group_2 t/data/example_1.faa t/data/example_2.faa ' =>
+ [ 'pan_genome_results_group_2.fa', 't/data/expected_output_groups_group_2.fa' ],
+ '-g t/data/example_groups -a gene_multifasta -n group_2,group_5 t/data/example_1.faa t/data/example_2.faa ' =>
+ [ 'pan_genome_results_group_2.fa', 't/data/expected_output_groups_group_2.fa' ],
+ '-g t/data/example_groups -n group_which_doesnt_exist t/data/example_1.faa t/data/example_2.faa' =>
+ [ 'empty_file', 't/data/empty_file' ],
+ '-g t/data/query_groups -a union t/data/query_1.fa t/data/query_2.fa t/data/query_3.fa' =>
+ [ 'pan_genome_results', 't/data/expected_union_of_groups.gg' ],
+ '-g t/data/query_groups -a intersection t/data/query_1.fa t/data/query_2.fa t/data/query_3.fa' =>
+ [ 'pan_genome_results', 't/data/expected_intersection_of_groups.gg' ],
+ '-g t/data/query_groups -a complement t/data/query_1.fa t/data/query_2.fa t/data/query_3.fa' =>
+ [ 'pan_genome_results', 't/data/expected_complement_of_groups.gg' ],
+ '-g t/data/query_groups -a difference -i t/data/query_1.fa -t t/data/query_2.fa,t/data/query_3.fa' =>
+ [ 'set_difference_unique_set_one', 't/data/expected_set_difference_unique_set_one' ],
+ '-g t/data/query_groups -a difference -i t/data/query_1.fa -t t/data/query_2.fa,t/data/query_3.fa' =>
+ [ 'set_difference_unique_set_two', 't/data/expected_set_difference_unique_set_two' ],
+ '-g t/data/query_groups -a difference -i t/data/query_1.fa -t t/data/query_2.fa,t/data/query_3.fa' =>
+ [ 'set_difference_common_set', 't/data/expected_set_difference_common_set' ],
+ '-g t/data/query_groups -a difference -i t/data/query_1.fa -t t/data/query_2.fa,t/data/query_3.fa ' =>
+ [ 'set_difference_unique_set_two_statistics.csv', 't/data/expected_set_difference_unique_set_two_statistics.csv' ],
+ '-g t/data/query_groups -a difference -i t/data/query_1.fa -t t/data/query_2.fa,t/data/query_3.fa ' =>
+ [ 'set_difference_unique_set_one_statistics.csv', 't/data/expected_set_difference_unique_set_one_statistics.csv' ],
+ '-g t/data/query_groups -a difference -i t/data/query_1.fa -t t/data/query_2.fa,t/data/query_3.fa ' =>
+ [ 'set_difference_common_set_statistics.csv', 't/data/expected_set_difference_common_set_statistics.csv' ],
+ '-g t/data/query_groups -a difference -i t/data/query_1.gff -t t/data/query_2.gff,t/data/query_3.gff' =>
+ [ 'set_difference_common_set_statistics.csv', 't/data/expected_gff_set_difference_common_set_statistics.csv' ],
+ '-h' => [ 'empty_file2', 't/data/empty_file' ],
+);
+
+mock_execute_script_and_check_output_sorted( $script_name, \%scripts_and_expected_files );
+
+unlink('set_difference_unique_set_two') if ( -e 'set_difference_unique_set_two' );
+unlink('set_difference_common_set') if ( -e 'set_difference_common_set' );
+unlink('pan_genome_results_group_5.fa') if ( -e 'pan_genome_results_group_5.fa' );
+unlink('gene_presence_absence.csv') if ( -e 'gene_presence_absence.csv' );
+unlink('set_difference_unique_set_two_statistics.csv') if ( -e 'set_difference_unique_set_two_statistics.csv' );
+unlink('set_difference_unique_set_one_statistics.csv') if ( -e 'set_difference_unique_set_one_statistics.csv' );
+unlink('set_difference_common_set_statistics.csv') if ( -e 'set_difference_common_set_statistics.csv' );
+unlink('pan_genome_reference.fa') if ( -e 'pan_genome_reference.fa' );
+unlink('set_difference_core_accessory_graph.dot') if ( -e 'set_difference_core_accessory_graph.dot' );
+unlink('set_difference_accessory_graph.dot') if ( -e 'set_difference_accessory_graph.dot' );
+
+done_testing();
diff --git a/t/Bio/Roary/CommandLine/Roary.t b/t/Bio/Roary/CommandLine/Roary.t
new file mode 100755
index 0000000..2e76d9b
--- /dev/null
+++ b/t/Bio/Roary/CommandLine/Roary.t
@@ -0,0 +1,322 @@
+#!/usr/bin/env perl
+use Moose;
+use Data::Dumper;
+use File::Path qw( remove_tree);
+use File::Which;
+use File::Path qw(make_path);
+use Cwd qw(abs_path getcwd);
+use File::Find::Rule;
+
+#Test changes current working directory so relative paths can get out of sync
+local $ENV{PERL5LIB} = join(':', ("$ENV{PERL5LIB}", abs_path('./lib'), abs_path('./t/lib')));
+local $ENV{PATH} = join(':', ("$ENV{PATH}", abs_path('./bin')));
+
+BEGIN { unshift( @INC, abs_path('./lib') ) }
+BEGIN { unshift( @INC, abs_path('./t/lib') ) }
+with 'TestHelper';
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::CommandLine::Roary');
+ use_ok('Bio::Roary::CommandLine::CreatePanGenome');
+ use Bio::Roary::SequenceLengths;
+}
+my $script_name = 'Bio::Roary::CommandLine::Roary';
+my $cwd = getcwd();
+
+local $ENV{PATH} = "$ENV{PATH}:./bin";
+my %scripts_and_expected_files;
+system('touch empty_file');
+cleanup_files();
+
+%scripts_and_expected_files = (
+
+ ' --dont_split_groups t/data/query_1.gff t/data/query_2.gff t/data/query_5.gff ' =>
+ [ 'gene_presence_absence.csv', 't/data/overall_gene_presence_absence.csv' ],
+ ' -j Local -t 1 --dont_split_groups t/data/query_1.gff t/data/query_2.gff t/data/query_5.gff ' =>
+ [ 'gene_presence_absence.csv', 't/data/overall_gene_presence_absence.csv' ],
+ ' -j Parallel --dont_split_groups t/data/query_1.gff t/data/query_2.gff t/data/query_5.gff ' =>
+ [ 'gene_presence_absence.csv', 't/data/overall_gene_presence_absence.csv' ],
+ ' -t 1 -j Parallel --dont_split_groups t/data/query_1.gff t/data/query_2.gff t/data/query_5.gff ' =>
+ [ 'gene_presence_absence.csv', 't/data/overall_gene_presence_absence.csv' ],
+ ' -j Local --dont_split_groups t/data/genbank_gbff/genbank1.gff t/data/genbank_gbff/genbank2.gff t/data/genbank_gbff/genbank3.gff' =>
+ [ 'gene_presence_absence.csv', 't/data/genbank_gbff/genbank_gene_presence_absence.csv' ],
+ '-h' => [ 'empty_file', 't/data/empty_file' ],
+);
+
+mock_execute_script_and_check_output_sorted( $script_name, \%scripts_and_expected_files, [ 0, 6, 7, 8, 9 ] );
+
+cleanup_files();
+
+%scripts_and_expected_files = (
+ ' -j Local --dont_split_groups t/data/query_1.gff t/data/query_2.gff t/data/query_5.gff ' =>
+ [ 'clustered_proteins', 't/data/clustered_proteins_pan_genome' ],
+ ' -j Parallel --dont_split_groups t/data/query_1.gff t/data/query_2.gff t/data/query_5.gff ' =>
+ [ 'clustered_proteins', 't/data/clustered_proteins_pan_genome' ],
+);
+
+mock_execute_script_and_check_output_sorted_groups( $script_name, \%scripts_and_expected_files, [ 0, 6, 7, 8, 9 ] );
+
+# Make sure faa files are cleaned up automatically
+ok( !( -e 'query_1.gff.proteome.faa' ), 'Check protein query_1.gff.proteome.faa is cleaned up' );
+ok( !( -e 'query_2.gff.proteome.faa' ), 'Check protein query_2.gff.proteome.faa is cleaned up' );
+ok( !( -e 'query_5.gff.proteome.faa' ), 'Check protein query_5.gff.proteome.faa is cleaned up' );
+
+cleanup_files();
+
+stderr_should_have($script_name,'-a', 'Looking for');
+
+my $current_cwd = getcwd();
+stderr_should_have($script_name,'-v --output_directory t/data/directory_which_doesnt_exist t/data/real_data_1.gff t/data/real_data_2.gff', 'Output directory created');
+ok( ( -e 't/data/directory_which_doesnt_exist/clustered_proteins' ), 'pan genome files should be in directory' );
+is(getcwd(),$current_cwd , 'current working directory should not have changed after script is finished');
+
+SKIP:
+{
+ skip "prank not installed", 11 unless ( which('prank') );
+
+ %scripts_and_expected_files =
+ ( '-j Local --dont_delete_files --dont_split_groups --output_multifasta_files t/data/real_data_1.gff t/data/real_data_2.gff' =>
+ [ 'pan_genome_sequences/mdoH.fa.aln', 't/data/mdoH.fa.aln' ], );
+ mock_execute_script_and_check_output( $script_name, \%scripts_and_expected_files );
+
+ ok( -e 'core_gene_alignment.aln', 'Core gene alignment exists' );
+
+ ok(
+ my $seq_len = Bio::Roary::SequenceLengths->new(
+ fasta_file => 'core_gene_alignment.aln',
+ ),
+ 'Check size of the core_gene_alignment.aln init'
+ );
+
+ my @keys = keys %{ $seq_len->sequence_lengths };
+ is( $seq_len->sequence_lengths->{ $keys[0] }, 64983, 'length of first sequence' );
+
+ ok( -e 'core_alignment_header.embl', 'Core gene alignment header exists' );
+
+ ok( -e 'accessory.tab' );
+ ok( -e 'core_accessory.tab' );
+ ok( -e 'number_of_conserved_genes.Rtab' );
+ ok( -e 'number_of_genes_in_pan_genome.Rtab' );
+ ok( -e 'number_of_new_genes.Rtab' );
+ ok( -e 'number_of_unique_genes.Rtab' );
+ ok( -e 'blast_identity_frequency.Rtab' );
+
+ cleanup_files();
+ %scripts_and_expected_files =
+ (
+'-j Local --output_multifasta_files t/data/core_alignment_gene_lookup/query_1.gff t/data/core_alignment_gene_lookup/query_2.gff t/data/core_alignment_gene_lookup/query_3.gff'
+ => [ 'core_gene_alignment.aln', 't/data/core_alignment_gene_lookup/expected_core_gene_alignment.aln' ], );
+ mock_execute_script_and_check_output( $script_name, \%scripts_and_expected_files );
+
+ cleanup_files();
+}
+
+SKIP:
+{
+ skip "mafft not installed", 11 unless ( which('mafft') );
+ %scripts_and_expected_files =
+ ( '-j Local --dont_delete_files --dont_split_groups --output_multifasta_files --mafft t/data/real_data_1.gff t/data/real_data_2.gff'
+ => [ 'pan_genome_sequences/mdoH.fa.aln', 't/data/mdoH_mafft.fa.aln' ], );
+ mock_execute_script_and_check_output( $script_name, \%scripts_and_expected_files );
+
+ ok( -e 'core_gene_alignment.aln', 'Core gene alignment exists' );
+}
+
+SKIP:
+{
+ skip "extended tests not run", 40 unless ( defined($ENV{ROARY_FULL_TESTS}));
+
+ %scripts_and_expected_files = (
+ '-o some_different_output t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'some_different_output', 't/data/expected_some_different_output' ],
+ '-o some_different_output -i 90 t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'some_different_output', 't/data/expected_some_different_output' ],
+ '-o some_different_output --translation_table 1 t/data/real_data_1.gff t/data/real_data_2.gff' =>
+ [ 'some_different_output', 't/data/expected_some_different_output' ],
+ '-p 2 -o some_different_output t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'some_different_output', 't/data/expected_some_different_output' ],
+ '-p 2 -i 90 t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'clustered_proteins', 't/data/expected_some_different_output' ],
+ '-i 90 t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'clustered_proteins', 't/data/expected_some_different_output' ],
+ '-p 2 --translation_table 1 t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'clustered_proteins', 't/data/expected_some_different_output' ],
+ );
+ mock_execute_script_and_check_output_sorted( $script_name, \%scripts_and_expected_files, [ 0 ] );
+
+ stderr_should_have($script_name,'-e --group_limit 10 t/data/real_data_1.gff t/data/real_data_2.gff', 'Exiting early because number of clusters is too high');
+ stderr_should_have($script_name,'-p 2 --group_limit 10 -e t/data/real_data_1.gff t/data/real_data_2.gff', 'Exiting early because number of clusters is too high');
+ stderr_should_have($script_name,'--core_definition 60 --group_limit 10 -e t/data/real_data_1.gff t/data/real_data_2.gff', 'Exiting early because number of clusters is too high');
+ stderr_should_have($script_name,'--mafft --group_limit 10 -e t/data/real_data_1.gff t/data/real_data_2.gff', 'Exiting early because number of clusters is too high');
+ stderr_should_have($script_name,'-o some_different_output --group_limit 10 -e t/data/real_data_1.gff t/data/real_data_2.gff', 'Exiting early because number of clusters is too high');
+ stderr_should_have($script_name,'--translation_table 1 --group_limit 10 -e t/data/real_data_1.gff t/data/real_data_2.gff', 'Exiting early because number of clusters is too high');
+ stderr_should_have($script_name,'--verbose_stats --group_limit 10 -e t/data/real_data_1.gff t/data/real_data_2.gff', 'Exiting early because number of clusters is too high');
+ stderr_should_not_have($script_name,'-e --group_limit 10 t/data/real_data_1.gff t/data/real_data_2.gff', 'Cant access the multifasta base directory');
+ stderr_should_have($script_name,'-v t/data/real_data_1.gff t/data/real_data_2.gff','Cleaning up files');
+ stderr_should_have($script_name,'-p 2 -v t/data/real_data_1.gff t/data/real_data_2.gff','Cleaning up files');
+ stderr_should_have($script_name,'--core_definition 60 -v t/data/real_data_1.gff t/data/real_data_2.gff','Cleaning up files');
+ stderr_should_have($script_name,'-i 90 -v t/data/real_data_1.gff t/data/real_data_2.gff','Cleaning up files');
+ stderr_should_have($script_name,'-i 30 t/data/real_data_1.gff t/data/real_data_2.gff','The percentage identity is too low');
+ stderr_should_not_have($script_name,'--dont_delete_files -v t/data/real_data_1.gff t/data/real_data_2.gff','Cleaning up files');
+ stderr_should_have($script_name,'-v --verbose_stats t/data/real_data_1.gff t/data/real_data_2.gff' ,'Cleaning up files');
+ stderr_should_have($script_name,'-v --group_limit 100000 -e t/data/real_data_1.gff t/data/real_data_2.gff' ,'Cleaning up files');
+
+ stderr_should_have($script_name,'--translation_table 1 -v t/data/real_data_1.gff t/data/real_data_2.gff' ,'Cleaning up files');
+ stderr_should_have($script_name,'-e -v t/data/real_data_1.gff t/data/real_data_2.gff','Creating files with the nucleotide sequences for every cluster');
+
+ SKIP:
+ {
+ skip "kraken not installed", 2 unless ( which('kraken') );
+ skip "kraken-report not installed", 2 unless ( which('kraken-report') );
+ stderr_should_not_have($script_name,'--group_limit 10 --qc t/data/real_data_1.gff t/data/real_data_2.gff', 'Exiting early because number of clusters is too high');
+ stderr_should_have($script_name,'-v --qc t/data/real_data_1.gff t/data/real_data_2.gff' ,'Running Kraken on each input assembly');
+ }
+
+ %scripts_and_expected_files = (
+ # output
+ '-o some_different_output -e t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'core_gene_alignment.aln', 't/data/expected_real_data_core_gene_alignment.aln' ],
+ '-o some_different_output -e --dont_delete_files t/data/real_data_1.gff t/data/real_data_2.gff' =>
+ [ 'pan_genome_sequences/mdoH.fa.aln', 't/data/mdoH.fa.aln' ],
+ '-o some_different_output --core_definition 60 t/data/real_data_1.gff t/data/real_data_2.gff' =>
+ [ 'summary_statistics.txt', 't/data/expected_core_60_summary_statistics.txt' ],
+ '-o some_different_output -e --mafft t/data/real_data_1.gff t/data/real_data_2.gff' =>
+ [ 'core_gene_alignment.aln', 't/data/expected_mafft_real_data_core_gene_alignment.aln' ],
+ # -e
+ '-e -i 95.3 t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'core_gene_alignment.aln', 't/data/expected_real_data_core_gene_alignment.aln' ],
+ '-e --translation_table 1 t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'core_gene_alignment.aln', 't/data/expected_real_data_core_gene_alignment.aln' ],
+ '-e -v t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'core_gene_alignment.aln', 't/data/expected_real_data_core_gene_alignment.aln' ],
+ '-e --verbose_stats t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'core_gene_alignment.aln', 't/data/expected_real_data_core_gene_alignment.aln' ],
+ '-e --group_limit 100000 -e t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'core_gene_alignment.aln', 't/data/expected_real_data_core_gene_alignment.aln' ],
+ '-e --qc t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'core_gene_alignment.aln', 't/data/expected_real_data_core_gene_alignment.aln' ],
+
+ # '-o some_different_output -v t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'empty_file', 't/data/empty_file' ],
+ # '-o some_different_output --verbose_stats t/data/real_data_1.gff t/data/real_data_2.gff' =>
+ # [ 'empty_file', 't/data/empty_file' ],
+ # '-o some_different_output --group_limit 100000 -e t/data/real_data_1.gff t/data/real_data_2.gff' =>
+ # [ 'empty_file', 't/data/empty_file' ],
+ # '-o some_different_output --qc t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'empty_file', 't/data/empty_file' ],
+ #
+ # # single parameters
+ '--core_definition 60 t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'summary_statistics.txt', 't/data/expected_core_60_summary_statistics.txt' ],
+ # '--translation_table 1 t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'empty_file', 't/data/empty_file' ],
+ # '--verbose_stats t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'empty_file', 't/data/empty_file' ],
+ # '--group_limit 100000 -e t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'empty_file', 't/data/empty_file' ],
+ # '--qc t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'empty_file', 't/data/empty_file' ],
+ #
+ # # Parallel
+ '-p 2 -e t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'core_gene_alignment.aln', 't/data/expected_real_data_core_gene_alignment.aln' ],
+ '-p 2 -e --dont_delete_files t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'pan_genome_sequences/mdoH.fa.aln', 't/data/mdoH.fa.aln' ],
+ '-p 2 --core_definition 60 t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'summary_statistics.txt', 't/data/expected_core_60_summary_statistics.txt' ],
+ '-p 2 -e --mafft t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'core_gene_alignment.aln', 't/data/expected_mafft_real_data_core_gene_alignment.aln' ],
+ # '-p 2 --verbose_stats t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'empty_file', 't/data/empty_file' ],
+ # '-p 2 --group_limit 100000 -e t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'empty_file', 't/data/empty_file' ],
+ # '-p 2 --qc t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'empty_file', 't/data/empty_file' ],
+ #
+ # # core definition
+ # '--core_definition 60 -e t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'empty_file', 't/data/empty_file' ],
+ # '--core_definition 60 -e --dont_delete_files t/data/real_data_1.gff t/data/real_data_2.gff' =>
+ # [ 'empty_file', 't/data/empty_file' ],
+ # '--core_definition 60 -e --mafft t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'empty_file', 't/data/empty_file' ],
+ # '--core_definition 60 -i 90 t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'empty_file', 't/data/empty_file' ],
+ # '--core_definition 60 --translation_table 1 t/data/real_data_1.gff t/data/real_data_2.gff' =>
+ # [ 'empty_file', 't/data/empty_file' ],
+ # '--core_definition 60 --verbose_stats t/data/real_data_1.gff t/data/real_data_2.gff' =>
+ # [ 'empty_file', 't/data/empty_file' ],
+ # '--core_definition 60 --group_limit 100000 -e t/data/real_data_1.gff t/data/real_data_2.gff' =>
+ # [ 'empty_file', 't/data/empty_file' ],
+ # '--core_definition 60 --qc t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'empty_file', 't/data/empty_file' ],
+ #
+ # # mafft
+ # '--mafft -i 90 t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'empty_file', 't/data/empty_file' ],
+ # '--mafft --translation_table 1 t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'empty_file', 't/data/empty_file' ],
+ # '--mafft --verbose_stats t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'empty_file', 't/data/empty_file' ],
+ # '--mafft --group_limit 100000 -e t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'empty_file', 't/data/empty_file' ],
+ # '--mafft --qc t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'empty_file', 't/data/empty_file' ],
+ #
+ #
+ # # dont_delete_files
+ # '--dont_delete_files -i 90 t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'empty_file', 't/data/empty_file' ],
+ # '--dont_delete_files --translation_table 1 t/data/real_data_1.gff t/data/real_data_2.gff' =>
+ # [ 'empty_file', 't/data/empty_file' ],
+
+ # '--dont_delete_files --verbose_stats t/data/real_data_1.gff t/data/real_data_2.gff' =>
+ # [ 'empty_file', 't/data/empty_file' ],
+ # '--dont_delete_files --group_limit 10 -e t/data/real_data_1.gff t/data/real_data_2.gff' =>
+ # [ 'empty_file', 't/data/empty_file' ],
+ # '--dont_delete_files --group_limit 100000 -e t/data/real_data_1.gff t/data/real_data_2.gff' =>
+ # [ 'empty_file', 't/data/empty_file' ],
+ # '--dont_delete_files --qc t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'empty_file', 't/data/empty_file' ],
+ #
+ # # change identity
+ # '-i 90 --translation_table 1 t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'empty_file', 't/data/empty_file' ],
+
+ # '-i 90 --verbose_stats t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'empty_file', 't/data/empty_file' ],
+ # '-i 90 --group_limit 10 -e t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'empty_file', 't/data/empty_file' ],
+ # '-i 90 --group_limit 100000 -e t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'empty_file', 't/data/empty_file' ],
+ # '-i 90 --qc t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'empty_file', 't/data/empty_file' ],
+ #
+ # # translation_table
+ # '--translation_table 1 --verbose_stats t/data/real_data_1.gff t/data/real_data_2.gff' =>
+ # [ 'empty_file', 't/data/empty_file' ],
+ # '--translation_table 1 --group_limit 100000 -e t/data/real_data_1.gff t/data/real_data_2.gff' =>
+ # [ 'empty_file', 't/data/empty_file' ],
+ # '--translation_table 1 --qc t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'empty_file', 't/data/empty_file' ],
+ #
+ #
+ # # verbose stats
+ # '--verbose_stats --group_limit 100000 -e t/data/real_data_1.gff t/data/real_data_2.gff' =>
+ # [ 'empty_file', 't/data/empty_file' ],
+ # '--verbose_stats --qc t/data/real_data_1.gff t/data/real_data_2.gff' => [ 'empty_file', 't/data/empty_file' ],
+ #
+ );
+ mock_execute_script_and_check_output( $script_name, \%scripts_and_expected_files );
+
+}
+
+cleanup_files();
+
+done_testing();
+
+sub cleanup_files {
+ remove_tree('pan_genome_sequences');
+ remove_tree('fixed_input_files');
+ remove_tree('t/data/directory_which_doesnt_exist');
+ remove_tree('locus_tags_gffs_output');
+ unlink('_blast_results');
+ unlink('_clustered');
+ unlink('_clustered.bak.clstr');
+ unlink('_clustered.clstr');
+ unlink('_combined_files');
+ unlink('_combined_files.groups');
+ unlink('_fasta_files');
+ unlink('_gff_files');
+ unlink('_inflated_mcl_groups');
+ unlink('_inflated_unsplit_mcl_groups');
+ unlink('_labeled_mcl_groups');
+ unlink('_uninflated_mcl_groups');
+ unlink('accessory.header.embl');
+ unlink('accessory.header.tab');
+ unlink('accessory.tab');
+ unlink('blast_identity_frequency.Rtab');
+ unlink('clustered_proteins');
+ unlink('core_accessory.header.embl');
+ unlink('core_accessory.header.tab');
+ unlink('core_accessory.tab');
+ unlink('core_gene_alignment.aln');
+ unlink('database_masking.asnb');
+ unlink('example_1.faa.tmp.filtered.fa');
+ unlink('example_2.faa.tmp.filtered.fa');
+ unlink('example_3.faa.tmp.filtered.fa');
+ unlink('gene_presence_absence.csv');
+ unlink('number_of_conserved_genes.Rtab');
+ unlink('number_of_genes_in_pan_genome.Rtab');
+ unlink('number_of_new_genes.Rtab');
+ unlink('number_of_unique_genes.Rtab');
+ unlink('pan_genome.fa');
+ unlink('query_1.gff.proteome.faa');
+ unlink('query_2.gff.proteome.faa');
+ unlink('query_3.gff.proteome.faa');
+ unlink('query_5.gff.proteome.faa');
+ unlink('real_data_1.gff.proteome.faa');
+ unlink('real_data_2.gff.proteome.faa');
+ unlink('pan_genome_reference.fa');
+ unlink('accessory_graph.dot');
+ unlink('core_accessory_graph.dot');
+ unlink('some_different_output');
+ unlink('core_alignment_header.embl');
+}
diff --git a/t/Bio/Roary/CommandLine/RoaryCoreAlignment.t b/t/Bio/Roary/CommandLine/RoaryCoreAlignment.t
new file mode 100644
index 0000000..cb609d1
--- /dev/null
+++ b/t/Bio/Roary/CommandLine/RoaryCoreAlignment.t
@@ -0,0 +1,27 @@
+#!/usr/bin/env perl
+use Moose;
+use Data::Dumper;
+use Cwd;
+
+BEGIN { unshift( @INC, './lib' ) }
+BEGIN { unshift( @INC, './t/lib' ) }
+with 'TestHelper';
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::CommandLine::RoaryCoreAlignment');
+}
+my $script_name = 'Bio::Roary::CommandLine::RoaryCoreAlignment';
+system('touch empty_file');
+my %scripts_and_expected_files = (
+ '-m t/data/core_alignment -s t/data/core_alignment.csv' =>
+ [ 'core_gene_alignment.aln', 't/data/expected_core_gene_alignment.aln' ],
+ '-m t/data/core_alignment -s t/data/core_alignment_core0.66.csv --core_definition 0.66' =>
+ [ 'core_gene_alignment.aln', 't/data/expected_core_gene_alignment_core0.66.aln' ],
+ '-h' =>
+ [ 'empty_file', 't/data/empty_file' ],
+);
+
+mock_execute_script_and_check_output( $script_name, \%scripts_and_expected_files );
+
+done_testing();
diff --git a/t/Bio/Roary/CommandLine/RoaryPostAnalysis.t b/t/Bio/Roary/CommandLine/RoaryPostAnalysis.t
new file mode 100755
index 0000000..68b1c86
--- /dev/null
+++ b/t/Bio/Roary/CommandLine/RoaryPostAnalysis.t
@@ -0,0 +1,108 @@
+#!/usr/bin/env perl
+use Moose;
+use Data::Dumper;
+use File::Path qw( remove_tree);
+use Cwd;
+
+BEGIN { unshift( @INC, './lib' ) }
+BEGIN { unshift( @INC, './t/lib' ) }
+with 'TestHelper';
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::CommandLine::RoaryPostAnalysis');
+}
+my $script_name = 'Bio::Roary::CommandLine::RoaryPostAnalysis';
+my $cwd = getcwd();
+
+local $ENV{PATH} = "$ENV{PATH}:./bin";
+
+system('cp t/data/post_analysis/* .');
+system('touch empty_file');
+
+my %scripts_and_expected_files = (
+ '-o clustered_proteins -p pan_genome.fa -s gene_presence_absence.csv -c _clustered.clstr -i _gff_files -f _fasta_files -j Local --dont_create_rplots --dont_split_groups' =>
+ [ 'clustered_proteins', 't/data/clustered_proteins_post_analysis' ],
+ '-h' =>
+ [ 'empty_file', 't/data/empty_file' ],
+);
+
+SKIP:
+{
+
+ skip "Tests dont take variablity into account", 2 if(1);
+ mock_execute_script_and_check_output_sorted_groups( $script_name, \%scripts_and_expected_files );
+
+ ok( -e 'number_of_unique_genes.Rtab', 'number_of_unique_genes.Rtab exists');
+ ok( -e 'number_of_new_genes.Rtab', 'number_of_new_genes exists');
+ ok( -e 'number_of_genes_in_pan_genome.Rtab', 'number_of_genes_in_pan_genome exists');
+ ok( -e 'number_of_conserved_genes.Rtab','number_of_conserved_genes');
+ ok( -e 'gene_presence_absence.csv', 'gene_presence_absence exists');
+ ok( -e 'core_accessory.tab', 'core_accessory.tab exists');
+ ok( -e 'core_accessory.header.embl','core_accessory.header.embl exists');
+ ok( -e 'accessory.tab','accessory.tab exists');
+ ok( -e 'accessory.header.embl','accessory.header.embl exists');
+ ok( -e 'summary_statistics.txt' ,'summary_statistics.txt exists');
+
+ compare_tab_files_with_variable_coordinates('accessory.header.embl', 't/data/post_analysis_expected/accessory.header.embl');
+ compare_tab_files_with_variable_coordinates('accessory.tab', 't/data/post_analysis_expected/accessory.tab');
+ compare_tab_files_with_variable_coordinates('core_accessory.header.embl', 't/data/post_analysis_expected/core_accessory.header.embl');
+ compare_tab_files_with_variable_coordinates('core_accessory.tab', 't/data/post_analysis_expected/core_accessory.tab');
+
+ cleanup_files();
+
+ system('cp t/data/post_analysis/* .');
+ system('touch empty_file');
+ %scripts_and_expected_files = (
+ '-t 1 -o clustered_proteins -p pan_genome.fa -s gene_presence_absence.csv -c _clustered.clstr -i _gff_files -f _fasta_files -j Local --dont_create_rplots --dont_split_groups' =>
+ [ 'clustered_proteins', 't/data/clustered_proteins_post_analysis' ],
+ '-h' =>
+ [ 'empty_file', 't/data/empty_file' ],
+ );
+
+ mock_execute_script_and_check_output_sorted_groups( $script_name, \%scripts_and_expected_files );
+
+ ok( -e 'number_of_unique_genes.Rtab', 'number_of_unique_genes.Rtab exists');
+ ok( -e 'number_of_new_genes.Rtab', 'number_of_new_genes exists');
+ ok( -e 'number_of_genes_in_pan_genome.Rtab', 'number_of_genes_in_pan_genome exists');
+ ok( -e 'number_of_conserved_genes.Rtab','number_of_conserved_genes');
+ ok( -e 'gene_presence_absence.csv', 'gene_presence_absence exists');
+ ok( -e 'core_accessory.tab', 'core_accessory.tab exists');
+ ok( -e 'core_accessory.header.embl','core_accessory.header.embl exists');
+ ok( -e 'accessory.tab','accessory.tab exists');
+ ok( -e 'accessory.header.embl','accessory.header.embl exists');
+
+ compare_tab_files_with_variable_coordinates('accessory.header.embl', 't/data/post_analysis_expected/accessory.header.embl');
+ compare_tab_files_with_variable_coordinates('accessory.tab', 't/data/post_analysis_expected/accessory.tab');
+ compare_tab_files_with_variable_coordinates('core_accessory.header.embl', 't/data/post_analysis_expected/core_accessory.header.embl');
+ compare_tab_files_with_variable_coordinates('core_accessory.tab', 't/data/post_analysis_expected/core_accessory.tab');
+
+}
+cleanup_files();
+done_testing();
+
+sub cleanup_files
+{
+ unlink('_clustered');
+ unlink('_clustered.bak.clstr');
+ unlink('_clustered.clstr');
+ unlink('_combined_files');
+ unlink('_combined_files.groups');
+ unlink('_fasta_files');
+ unlink('_gff_files');
+ unlink('_uninflated_mcl_groups');
+ unlink('query_1.gff.proteome.faa');
+ unlink('query_2.gff.proteome.faa');
+ unlink('query_6.gff.proteome.faa');
+ unlink('accessory.header.embl');
+ unlink('accessory.tab');
+ unlink('core_accessory.header.embl');
+ unlink('core_accessory.tab');
+ unlink('gene_presence_absence.csv');
+ unlink('number_of_unique_genes.Rtab');
+ unlink('number_of_new_genes.Rtab');
+ unlink('number_of_genes_in_pan_genome.Rtab');
+ unlink('number_of_conserved_genes.Rtab');
+}
+
+
diff --git a/t/Bio/Roary/CommandLine/RoaryReorderSpreadsheet.t b/t/Bio/Roary/CommandLine/RoaryReorderSpreadsheet.t
new file mode 100644
index 0000000..27ed114
--- /dev/null
+++ b/t/Bio/Roary/CommandLine/RoaryReorderSpreadsheet.t
@@ -0,0 +1,52 @@
+#!/usr/bin/env perl
+use Moose;
+use Data::Dumper;
+use Cwd;
+
+BEGIN { unshift( @INC, './lib' ) }
+BEGIN { unshift( @INC, './t/lib' ) }
+with 'TestHelper';
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::CommandLine::RoaryReorderSpreadsheet');
+}
+my $script_name = 'Bio::Roary::CommandLine::RoaryReorderSpreadsheet';
+system('touch empty_file');
+my %scripts_and_expected_files = (
+ '-t t/data/reorder_isolates.tre -s t/data/reorder_isolates_input.csv' =>
+ [ 'reordered_spreadsheet.csv', 't/data/reorder_isolates_expected_output.csv' ],
+ '-t t/data/reorder_isolates.tre -s t/data/reorder_isolates_input.csv -o different_output_name.csv' =>
+ [ 'different_output_name.csv', 't/data/reorder_isolates_expected_output.csv' ],
+ '-t t/data/reorder_isolates.tre -s t/data/reorder_isolates_input.csv -f newick' =>
+ [ 'reordered_spreadsheet.csv', 't/data/reorder_isolates_expected_output.csv' ],
+
+ '-t t/data/reorder_isolates.tre -s t/data/reorder_isolates_input.csv -a depth' =>
+ [ 'reordered_spreadsheet.csv', 't/data/reorder_isolates_expected_output.csv' ],
+ '-t t/data/reorder_isolates.tre -s t/data/reorder_isolates_input.csv -a depth -b height' =>
+ [ 'reordered_spreadsheet.csv', 't/data/reorder_isolates_expected_output_depth_height.csv' ],
+ '-t t/data/reorder_isolates.tre -s t/data/reorder_isolates_input.csv -a depth -b creation' =>
+ [ 'reordered_spreadsheet.csv', 't/data/reorder_isolates_expected_output_depth_creation.csv' ],
+ '-t t/data/reorder_isolates.tre -s t/data/reorder_isolates_input.csv -a depth -b alpha' =>
+ [ 'reordered_spreadsheet.csv', 't/data/reorder_isolates_expected_output_depth_alpha.csv' ],
+ '-t t/data/reorder_isolates.tre -s t/data/reorder_isolates_input.csv -a depth -b revalpha' =>
+ [ 'reordered_spreadsheet.csv', 't/data/reorder_isolates_expected_output_depth_revalpha.csv' ],
+
+ '-t t/data/reorder_isolates.tre -s t/data/reorder_isolates_input.csv -a breadth' =>
+ [ 'reordered_spreadsheet.csv', 't/data/reorder_isolates_expected_output.csv' ],
+ '-t t/data/reorder_isolates.tre -s t/data/reorder_isolates_input.csv -a breadth -b height' =>
+ [ 'reordered_spreadsheet.csv', 't/data/reorder_isolates_expected_output_breadth_height.csv' ],
+ '-t t/data/reorder_isolates.tre -s t/data/reorder_isolates_input.csv -a breadth -b creation' =>
+ [ 'reordered_spreadsheet.csv', 't/data/reorder_isolates_expected_output_breadth_creation.csv' ],
+ '-t t/data/reorder_isolates.tre -s t/data/reorder_isolates_input.csv -a breadth -b alpha' =>
+ [ 'reordered_spreadsheet.csv', 't/data/reorder_isolates_expected_output_breadth_alpha.csv' ],
+ '-t t/data/reorder_isolates.tre -s t/data/reorder_isolates_input.csv -a breadth -b revalpha' =>
+ [ 'reordered_spreadsheet.csv', 't/data/reorder_isolates_expected_output_breadth_revalpha.csv' ],
+
+ '-h' =>
+ [ 'empty_file', 't/data/empty_file' ],
+);
+
+mock_execute_script_and_check_output( $script_name, \%scripts_and_expected_files );
+
+done_testing();
diff --git a/t/Bio/Roary/CommandLine/TransferAnnotationToGroups.t b/t/Bio/Roary/CommandLine/TransferAnnotationToGroups.t
new file mode 100644
index 0000000..e56d407
--- /dev/null
+++ b/t/Bio/Roary/CommandLine/TransferAnnotationToGroups.t
@@ -0,0 +1,26 @@
+#!/usr/bin/env perl
+use Moose;
+use Data::Dumper;
+use Cwd;
+
+BEGIN { unshift( @INC, './lib' ) }
+BEGIN { unshift( @INC, './t/lib' ) }
+with 'TestHelper';
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::CommandLine::TransferAnnotationToGroups');
+}
+my $script_name = 'Bio::Roary::CommandLine::TransferAnnotationToGroups';
+my $cwd = getcwd();
+system('touch empty_file');
+my %scripts_and_expected_files = (
+ '-g t/data/query_groups t/data/query_1.gff t/data/query_2.gff t/data/query_3.gff' =>
+ [ 'reannotated_groups', 't/data/expected_reannotated_groups_file' ],
+ '-h' =>
+ [ 'empty_file', 't/data/empty_file' ],
+);
+
+mock_execute_script_and_check_output_sorted( $script_name, \%scripts_and_expected_files );
+
+done_testing();
diff --git a/t/Bio/Roary/ContigsToGeneIDsFromGFF.t b/t/Bio/Roary/ContigsToGeneIDsFromGFF.t
new file mode 100755
index 0000000..ce4c36c
--- /dev/null
+++ b/t/Bio/Roary/ContigsToGeneIDsFromGFF.t
@@ -0,0 +1,76 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+
+BEGIN { unshift( @INC, './lib' ) }
+$ENV{PATH} .= ":./bin";
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::ContigsToGeneIDsFromGFF');
+}
+
+ok(
+ my $obj = Bio::Roary::ContigsToGeneIDsFromGFF->new(
+ gff_file => 't/data/query_1.gff'
+ ),
+ 'Initialise contigs to gene ids obj'
+);
+
+is_deeply(
+ $obj->contig_to_ids,
+ {
+ 'abc|SC|contig000001' => [
+ '1_1', 'abc_00002', 'abc_00003', 'abc_00004', '1_2', 'abc_00006', '1_3', 'abc_00008',
+ 'abc_01705', 'abc_00010', 'abc_00011', 'abc_00012', 'abc_00013', 'abc_00014', '1_6', 'abc_00016'
+ ]
+ },
+ 'Contigs match expected with standard output'
+);
+
+ok(
+ $obj = Bio::Roary::ContigsToGeneIDsFromGFF->new(
+ gff_file => 't/data/query_1_alternative_patterns.gff'
+ ),
+ 'Initialise contigs to gene ids obj with alternative ID patterns'
+);
+is_deeply(
+ $obj->contig_to_ids,
+ {
+ 'abc|SC|contig000001' => [ '1_1', 'abc_00002', 'abc_00003', 'abc_00004', '1_2', 'abc_00006' ]
+ },
+ 'Contigs match expected with alternative output'
+);
+
+is_deeply(
+ $obj->_genes_annotation,
+ [
+ {
+ 'database_annotation_exists' => 1,
+ 'product' => 'superantigen-like protein',
+ 'end' => '3337',
+ 'start' => '2621',
+ 'contig' => 'abc|SC|contig000001',
+ 'id_name' => 'abc_00004'
+ },
+ {
+ 'database_annotation_exists' => 1,
+ 'product' => 'hypothetical protein',
+ 'end' => '4170',
+ 'start' => '3445',
+ 'contig' => 'abc|SC|contig000001',
+ 'id_name' => '1_2'
+ },
+ {
+ 'database_annotation_exists' => 1,
+ 'product' => 'superantigen-like protein',
+ 'end' => '4990',
+ 'start' => '4265',
+ 'contig' => 'abc|SC|contig000001',
+ 'id_name' => 'abc_00006'
+ }
+ ],
+ 'Product annotation with non standard format'
+);
+done_testing();
diff --git a/t/Bio/Roary/EmblGroups.t b/t/Bio/Roary/EmblGroups.t
new file mode 100644
index 0000000..2d3243a
--- /dev/null
+++ b/t/Bio/Roary/EmblGroups.t
@@ -0,0 +1,47 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+
+BEGIN { unshift( @INC, './lib' ) }
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::Output::EmblGroups');
+}
+
+
+my $annotate_groups = Bio::Roary::AnnotateGroups->new(
+ gff_files => ['t/data/query_1.gff','t/data/query_2.gff','t/data/query_3.gff'],
+ groups_filename => 't/data/query_groups',
+);
+
+my $analyse_groups = Bio::Roary::AnalyseGroups->new(
+ fasta_files => ['t/data/query_1.fa','t/data/query_2.fa','t/data/query_3.fa'],
+ groups_filename => 't/data/query_groups'
+);
+
+ok(my $obj = Bio::Roary::Output::EmblGroups->new(
+ output_filename => 'group_statitics.csv',
+ annotate_groups_obj => $annotate_groups,
+ analyse_groups_obj => $analyse_groups
+), 'initialise embl groups');
+
+is($obj->_get_heat_map_colour(['a','b','c','d'], 4),2, 'heatmap colour');
+is($obj->_get_heat_map_colour(['a','b','c'], 4),16, 'heatmap colour');
+is($obj->_get_heat_map_colour(['a','b'], 4),3, 'heatmap colour');
+is($obj->_get_heat_map_colour(['a'], 4),4, 'heatmap colour');
+
+
+is($obj->_get_heat_map_colour(['a','b','c','d','e','f','g','h','i','j'], 10),2, 'heatmap colour loop over each colour 10');
+is($obj->_get_heat_map_colour(['a','b','c','d','e','f','g','h','i' ], 10),15, 'heatmap colour loop over each colour 9');
+is($obj->_get_heat_map_colour(['a','b','c','d','e','f','g','h' ], 10),16, 'heatmap colour loop over each colour 8');
+is($obj->_get_heat_map_colour(['a','b','c','d','e','f','g' ], 10),10, 'heatmap colour loop over each colour 7');
+is($obj->_get_heat_map_colour(['a','b','c','d','e','f' ], 10),7, 'heatmap colour loop over each colour 6');
+is($obj->_get_heat_map_colour(['a','b','c','d','e' ], 10),3, 'heatmap colour loop over each colour 5');
+is($obj->_get_heat_map_colour(['a','b','c','d' ], 10),8, 'heatmap colour loop over each colour 4');
+is($obj->_get_heat_map_colour(['a','b','c' ], 10),9, 'heatmap colour loop over each colour 3');
+is($obj->_get_heat_map_colour(['a','b' ], 10),5, 'heatmap colour loop over each colour 2');
+is($obj->_get_heat_map_colour(['a' ], 10),4, 'heatmap colour loop over each colour 1 ');
+
+done_testing();
diff --git a/t/Bio/Roary/External/Blastp.t b/t/Bio/Roary/External/Blastp.t
new file mode 100644
index 0000000..826ad4f
--- /dev/null
+++ b/t/Bio/Roary/External/Blastp.t
@@ -0,0 +1,44 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use Cwd;
+
+
+BEGIN { unshift( @INC, './lib' ) }
+use Bio::Roary::External::Makeblastdb;
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::External::Blastp');
+}
+
+my $cwd = getcwd();
+my $obj;
+
+ok($obj = Bio::Roary::External::Blastp->new(
+ fasta_file => 't/data/some_fasta_file.fa',
+ blast_database => 'some_blast_database',
+ exec => $cwd.'/t/bin/dummy_blastp',
+),'initialise object');
+
+is($obj->_command_to_run, $cwd.'/t/bin/dummy_blastp -query t/data/some_fasta_file.fa -db some_blast_database -evalue 1e-06 -num_threads 1 -outfmt 6 -max_target_seqs 2000 | awk \'{ if ($3 > 98) print $0;}\' 2> /dev/null 1> results.out', 'Command constructed as expected');
+ok($obj->run(), 'run dummy command');
+unlink('results.out');
+
+done_testing();
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
diff --git a/t/Bio/Roary/External/Cdhit.t b/t/Bio/Roary/External/Cdhit.t
new file mode 100644
index 0000000..d64af7b
--- /dev/null
+++ b/t/Bio/Roary/External/Cdhit.t
@@ -0,0 +1,39 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use Cwd;
+
+BEGIN { unshift( @INC, './lib' ) }
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::External::Cdhit');
+}
+
+my $cwd = getcwd();
+my $obj;
+
+ok($obj = Bio::Roary::External::Cdhit->new(
+ input_file => 't/data/some_fasta_file.fa',
+ output_base => 'output',
+ exec => $cwd.'/t/bin/dummy_cd-hit',
+),'initialise object');
+
+is($obj->_command_to_run, $cwd.'/t/bin/dummy_cd-hit -i t/data/some_fasta_file.fa -o output -T 1 -M 1800 -g 1 -s 1 -d 256 -c 1 > /dev/null 2>&1', 'Command constructed as expected');
+ok($obj->run(), 'run dummy command');
+unlink('output');
+unlink('output.clstr');
+unlink('output.bak.clstr');
+
+
+ok($obj = Bio::Roary::External::Cdhit->new(
+ input_file => 't/data/some_fasta_file.fa',
+ output_base => 'output',
+ exec => $cwd.'/t/bin/dummy_cd-hit',
+ cpus => 1000
+),'initialise object with lots of threads');
+is($obj->_command_to_run, $cwd.'/t/bin/dummy_cd-hit -i t/data/some_fasta_file.fa -o output -T 40 -M 1800 -g 1 -s 1 -d 256 -c 1 > /dev/null 2>&1', 'number of threads capped at a lower level');
+
+
+done_testing();
diff --git a/t/Bio/Roary/External/CheckTools.t b/t/Bio/Roary/External/CheckTools.t
new file mode 100644
index 0000000..dddfee4
--- /dev/null
+++ b/t/Bio/Roary/External/CheckTools.t
@@ -0,0 +1,23 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use Cwd;
+use Test::Output;
+
+BEGIN { unshift( @INC, './lib' ) }
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::External::CheckTools');
+}
+ok( my $check_tools = Bio::Roary::External::CheckTools->new(), 'initialise checking for tools' );
+for my $tool ( ( 'parallel', 'blastp', 'makeblastdb', 'mcl', 'bedtools', 'prank', 'mafft', 'grep', 'sed', 'awk', ) ) {
+ my $pattern = "Looking for '$tool' - found ";
+ stderr_like { $check_tools->check_tool($tool); } qr/$pattern/, "Check for $tool";
+}
+
+stderr_like { $check_tools->check_all_tools; } qr/Looking for /, "Check for all tools";
+1;
+
+done_testing();
diff --git a/t/Bio/Roary/External/Mafft.t b/t/Bio/Roary/External/Mafft.t
new file mode 100644
index 0000000..10f702d
--- /dev/null
+++ b/t/Bio/Roary/External/Mafft.t
@@ -0,0 +1,43 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use Cwd;
+use Test::Files;
+
+BEGIN { unshift( @INC, './lib' ) }
+BEGIN {
+ use Test::Most;
+ use Bio::Roary::SortFasta;
+ use_ok('Bio::Roary::External::Mafft');
+}
+
+ok(
+ my $obj = Bio::Roary::External::Mafft->new(
+ input_filename => 't/data/mafft_input.fa',
+ output_filename => 't/data/mafft_input.fa.aln',
+ job_runner => 'Local'
+ ),
+ 'initialise mafft obj'
+);
+
+is(
+ $obj->_command_to_run,
+'mafft --auto --quiet t/data/mafft_input.fa > t/data/mafft_input.fa.aln',
+ 'Command constructed as expected'
+);
+
+ok( $obj->run(), 'run mafft' );
+
+ok(-e 't/data/mafft_input.fa.aln', 'output file exists');
+my $sort_fasta_after_revtrans = Bio::Roary::SortFasta->new(
+ input_filename => 't/data/mafft_input.fa.aln',
+ remove_nnn_from_end => 1,
+);
+$sort_fasta_after_revtrans->sort_fasta->replace_input_with_output_file;
+
+compare_ok( 't/data/mafft_input.fa.aln', 't/data/expected_mafft_input.fa.aln', "output for mafft matches" );
+
+unlink('t/data/mafft_input.fa.aln');
+
+done_testing();
diff --git a/t/Bio/Roary/External/Makeblastdb.t b/t/Bio/Roary/External/Makeblastdb.t
new file mode 100644
index 0000000..02dab30
--- /dev/null
+++ b/t/Bio/Roary/External/Makeblastdb.t
@@ -0,0 +1,32 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use Cwd;
+
+BEGIN { unshift( @INC, './lib' ) }
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::External::Makeblastdb');
+}
+
+my $cwd = getcwd();
+my $obj;
+
+ok($obj = Bio::Roary::External::Makeblastdb->new(
+ fasta_file => 't/data/some_fasta_file.fa',
+ exec => $cwd.'/t/bin/dummy_makeblastdb',
+ mask_data => 'masking_data_file'
+),'initialise object');
+
+is($obj->_command_to_run, $cwd.'/t/bin/dummy_makeblastdb -in t/data/some_fasta_file.fa -dbtype prot -parse_seqids -out '.$obj->_working_directory->dirname().'/output_contigs -logfile /dev/null', 'Command constructed as expected');
+ok($obj->run(), 'run dummy command');
+
+unlink("output_contigs.phr");
+unlink("output_contigs.pin");
+unlink("output_contigs.psq");
+
+1;
+
+done_testing();
diff --git a/t/Bio/Roary/External/Mcl.t b/t/Bio/Roary/External/Mcl.t
new file mode 100644
index 0000000..a062bcc
--- /dev/null
+++ b/t/Bio/Roary/External/Mcl.t
@@ -0,0 +1,54 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use Cwd;
+use Test::Files;
+
+BEGIN { unshift( @INC, './lib' ) }
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::External::Mcl');
+}
+
+my $cwd = getcwd();
+my $obj;
+
+
+ok(
+ $obj = Bio::Roary::External::Mcl->new(
+ blast_results => 'some_blast_results',
+ mcxdeblast_exec => $cwd . '/t/bin/dummy_mcxdeblast',
+ mcl_exec => $cwd . '/t/bin/dummy_mcl',
+ output_file => 'output.groups'
+ ),
+ 'initialise object with dummy values'
+);
+
+is(
+ $obj->_command_to_run,
+ $cwd
+ . '/t/bin/dummy_mcxdeblast -m9 --score=r --line-mode=abc some_blast_results 2> /dev/null | '
+ . $cwd
+ . '/t/bin/dummy_mcl - --abc -I 1.5 -o output.groups > /dev/null 2>&1',
+ 'Command constructed as expected'
+);
+ok( $obj->run(), 'run dummy command' );
+
+unlink('output.groups');
+
+ok(
+ $obj = Bio::Roary::External::Mcl->new(
+ blast_results => 't/data/blast_results',
+ ),
+ 'initialise object with real values'
+);
+ok( $obj->run(), 'run the real command' );
+compare_ok('output_groups', 't/data/expected_output_groups', 'outgroups as expected');
+
+unlink('output_groups');
+
+1;
+
+done_testing();
diff --git a/t/Bio/Roary/External/Prank.t b/t/Bio/Roary/External/Prank.t
new file mode 100755
index 0000000..c09fa35
--- /dev/null
+++ b/t/Bio/Roary/External/Prank.t
@@ -0,0 +1,44 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use Cwd;
+use Test::Files;
+use Bio::Roary::SortFasta;
+
+BEGIN { unshift( @INC, './lib' ) }
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::External::Prank');
+}
+
+ok(
+ my $obj = Bio::Roary::External::Prank->new(
+ input_filename => 't/data/prank_input.fa',
+ output_filename => 't/data/prank_input.fa.aln',
+ job_runner => 'Local'
+ ),
+ 'initialise prank obj'
+);
+
+is(
+ $obj->_command_to_run,
+'prank -d=t/data/prank_input.fa -o=t/data/prank_input.fa.aln -codon -F -quiet -once > /dev/null 2>&1 && mv t/data/prank_input.fa.aln*.fas t/data/prank_input.fa.aln',
+ 'Command constructed as expected'
+);
+
+ok( $obj->run(), 'run prank' );
+
+ok(-e 't/data/prank_input.fa.aln', 'output file exists');
+my $sort_fasta_after_revtrans = Bio::Roary::SortFasta->new(
+ input_filename => 't/data/prank_input.fa.aln',
+ remove_nnn_from_end => 1,
+);
+$sort_fasta_after_revtrans->sort_fasta->replace_input_with_output_file;
+
+compare_ok( 't/data/prank_input.fa.aln', 't/data/expected_prank_input.fa.aln', "output for prank matches" );
+
+unlink('t/data/prank_input.fa.aln');
+
+done_testing();
diff --git a/t/Bio/Roary/ExtractCoreGenesFromSpreadsheet.t b/t/Bio/Roary/ExtractCoreGenesFromSpreadsheet.t
new file mode 100755
index 0000000..92c747d
--- /dev/null
+++ b/t/Bio/Roary/ExtractCoreGenesFromSpreadsheet.t
@@ -0,0 +1,33 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+
+BEGIN { unshift( @INC, './lib' ) }
+$ENV{PATH} .= ":./bin";
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::ExtractCoreGenesFromSpreadsheet');
+}
+
+my $obj;
+
+ok($obj = Bio::Roary::ExtractCoreGenesFromSpreadsheet->new(
+ spreadsheet => 't/data/core_group_statistics.csv',
+),'initalise obj');
+is_deeply($obj->ordered_core_genes, ['argF','speH','group_5'], 'Correct ordering');
+is_deeply($obj->sample_names_to_genes, {
+ 'query_2' => {
+ '2_3' => 1,
+ '2_7' => 1,
+ '2_2' => 1
+ },
+ 'query_1' => {
+ '1_6' => 1,
+ '1_3' => 1,
+ '1_2' => 1
+ }
+ }, 'Correct of sample names to genes is correct');
+
+done_testing();
diff --git a/t/Bio/Roary/ExtractProteomeFromGFFs.t b/t/Bio/Roary/ExtractProteomeFromGFFs.t
new file mode 100755
index 0000000..e670f1b
--- /dev/null
+++ b/t/Bio/Roary/ExtractProteomeFromGFFs.t
@@ -0,0 +1,82 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use File::Basename;
+use Test::Files;
+
+BEGIN { unshift( @INC, './lib' ) }
+$ENV{PATH} .= ":./bin";
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::ExtractProteomeFromGFFs');
+}
+
+my $plot_groups_obj;
+
+ok(
+ $plot_groups_obj = Bio::Roary::ExtractProteomeFromGFFs->new(
+ gff_files => [ 't/data/example_annotation.gff', 't/data/example_annotation_2.gff' ],
+ ),
+ 'initialise object'
+);
+
+my @sorted_fasta_files = map { basename($_) } sort( @{ $plot_groups_obj->fasta_files() } );
+my @sorted_expected_files = sort( ( 'example_annotation.gff.proteome.faa', 'example_annotation_2.gff.proteome.faa' ) );
+
+is_deeply( \@sorted_fasta_files, \@sorted_expected_files, 'one file created' );
+
+compare_ok( $plot_groups_obj->fasta_files->[0] ,
+ 't/data/example_annotation.gff.proteome.faa.expected',
+ 'content of proteome 1 as expected'
+);
+
+unlink('example_annotation.gff.proteome.faa');
+unlink('example_annotation_2.gff.proteome.faa');
+
+ok(
+ $plot_groups_obj = Bio::Roary::ExtractProteomeFromGFFs->new(
+ gff_files => [ 't/data/genbank_gbff/genbank1.gff', 't/data/genbank_gbff/genbank2.gff', 't/data/genbank_gbff/genbank3.gff' ],
+ ),
+ 'initialise object with genbank gff files'
+);
+ at sorted_fasta_files = map { basename($_) } sort( @{ $plot_groups_obj->fasta_files() } );
+ at sorted_expected_files = sort( ( 'genbank1.gff.proteome.faa', 'genbank2.gff.proteome.faa', 'genbank3.gff.proteome.faa' ) );
+
+is_deeply( \@sorted_fasta_files, \@sorted_expected_files, 'GB files created output' );
+
+for my $full_filename ( @{ $plot_groups_obj->fasta_files() } ) {
+ my $base_filename = basename($full_filename);
+ compare_ok($full_filename,
+ 't/data/genbank_gbff/' . $base_filename . '.expected',
+ "content of proteome $full_filename as expected"
+ );
+}
+
+unlink('genbank1.gff.proteome.faa');
+unlink('genbank2.gff.proteome.faa');
+unlink('genbank3.gff.proteome.faa');
+
+ok(
+ $plot_groups_obj = Bio::Roary::ExtractProteomeFromGFFs->new(
+ gff_files => [ 't/data/locus_tag_gffs/query_1.gff', 't/data/locus_tag_gffs/query_2.gff', 't/data/locus_tag_gffs/query_3.gff' ],
+ ),
+ 'initialise object with locus tag id gff files'
+);
+ at sorted_fasta_files = map { basename($_) } sort( @{ $plot_groups_obj->fasta_files() } );
+ at sorted_expected_files = sort( ( 'query_1.gff.proteome.faa', 'query_2.gff.proteome.faa', 'query_3.gff.proteome.faa' ) );
+
+is_deeply( \@sorted_fasta_files, \@sorted_expected_files, 'locus tag id files created output' );
+
+for my $full_filename ( @{ $plot_groups_obj->fasta_files() } ) {
+ my $base_filename = basename($full_filename);
+ compare_ok($full_filename, 't/data/locus_tag_gffs/' . $base_filename . '.expected' ,
+ "content of proteome $full_filename as expected" );
+}
+
+unlink('query_1.gff.proteome.faa');
+unlink('query_2.gff.proteome.faa');
+unlink('query_3.gff.proteome.faa');
+
+done_testing();
diff --git a/t/Bio/Roary/FilterFullClusters.t b/t/Bio/Roary/FilterFullClusters.t
new file mode 100644
index 0000000..149ca5e
--- /dev/null
+++ b/t/Bio/Roary/FilterFullClusters.t
@@ -0,0 +1,36 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use Test::Files;
+
+BEGIN { unshift( @INC, './lib' ) }
+$ENV{PATH} .= ":./bin";
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::FilterFullClusters');
+}
+
+ok(my $filter_clusters = Bio::Roary::FilterFullClusters->new(
+ clusters_filename => 't/data/clusters_to_inflate',
+ fasta_file => 't/data/clusters_input.fa',
+ number_of_input_files => 6,
+ output_file => 'output_filtered.fa',
+ _greater_than_or_equal => 1,
+ cdhit_input_fasta_file => 't/data/clusters_to_inflate_original_input.fa',
+ cdhit_output_fasta_file => 'filtered_original_input.fa',
+ output_groups_file => 'output_groups',
+ ),'initialise object');
+ok($filter_clusters->filter_full_clusters_from_fasta(),'filter the clusters');
+ok($filter_clusters->filter_complete_cluster_from_original_fasta(),'filter original input and save full groups');
+
+compare_ok('output_filtered.fa', 't/data/expected_output_filtered.fa', 'content as expected');
+compare_ok('output_groups', 't/data/expected_output_groups_cdhit', 'content as expected');
+compare_ok('filtered_original_input.fa', 't/data/expected_filtered_original_input.fa', 'content as expected');
+
+unlink('output_groups');
+unlink('filtered_original_input.fa');
+unlink('output_filtered.fa');
+
+done_testing();
diff --git a/t/Bio/Roary/GeneNamesFromGFF.t b/t/Bio/Roary/GeneNamesFromGFF.t
new file mode 100755
index 0000000..8cc5cf2
--- /dev/null
+++ b/t/Bio/Roary/GeneNamesFromGFF.t
@@ -0,0 +1,94 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+
+BEGIN { unshift( @INC, './lib' ) }
+$ENV{PATH} .= ":./bin";
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::GeneNamesFromGFF');
+}
+
+my $obj;
+
+ok(
+ $obj = Bio::Roary::GeneNamesFromGFF->new(
+ gff_file => 't/data/query_1.gff'
+ ),
+ 'initialise reading GFF file'
+);
+is_deeply(
+ $obj->ids_to_gene_name,
+ {
+ '1_3' => 'argF',
+ '1_1' => 'different',
+ '1_2' => 'speH',
+ 'abc_00016' => 'yfnB',
+ 'abc_00008' => 'arcC1'
+ },
+ 'ids to gene names as expected'
+);
+
+is_deeply(
+ $obj->ids_to_gene_size,
+ {
+ 'abc_00012' => 188,
+ '1_1' => 959,
+ 'abc_00004' => 716,
+ 'abc_00006' => 725,
+ 'abc_00008' => 935,
+ '1_6' => 134,
+ 'abc_00014' => 134,
+ 'abc_01705' => 1556,
+ 'abc_00013' => 75,
+ 'abc_00010' => 227,
+ '1_2' => 725,
+ 'abc_00011' => 947,
+ 'abc_00016' => 686,
+ '1_3' => 1001,
+ 'abc_00002' => 146,
+ 'abc_00003' => 197
+ },
+ 'ids to gene lengths as expected'
+);
+
+ok(
+ $obj = Bio::Roary::GeneNamesFromGFF->new(
+ gff_file => 't/data/query_2.gff'
+ ),
+ 'initialise reading another GFF file'
+);
+is_deeply(
+ $obj->ids_to_gene_name,
+ {
+ '2_3' => 'argF',
+ '2_1' => 'hly',
+ '2_2' => 'speH',
+ 'abc_00016' => 'yfnB',
+ 'abc_00008' => 'arcC1'
+ },
+ 'ids to gene names as expected again'
+);
+
+ok(
+ $obj = Bio::Roary::GeneNamesFromGFF->new(
+ gff_file => 't/data/locus_tag_gffs/query_1.gff'
+ ),
+ 'initialise a GFF file with locus tags only'
+);
+
+is_deeply(
+ $obj->ids_to_gene_name,
+ {
+ 'abc_00005' => 'speH',
+ 'abc_00007' => 'argF',
+ 'abc_00001' => 'different',
+ 'abc_00016' => 'yfnB',
+ 'abc_00008' => 'arcC1'
+ },
+ 'ids to gene names with GFF file with locus tags only'
+);
+
+done_testing();
diff --git a/t/Bio/Roary/GroupLabels.t b/t/Bio/Roary/GroupLabels.t
new file mode 100644
index 0000000..d3fc2f0
--- /dev/null
+++ b/t/Bio/Roary/GroupLabels.t
@@ -0,0 +1,25 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use Test::Files;
+
+BEGIN { unshift( @INC, './lib' ) }
+$ENV{PATH} .= ":./bin";
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::GroupLabels');
+}
+
+ok(
+ my $obj = Bio::Roary::GroupLabels->new(
+ groups_filename => 't/data/example_groups_without_labels'
+ ),
+ 'initialise with a groups file'
+);
+ok($obj->add_labels, 'Add labels to groups');
+compare_ok($obj->output_filename, 't/data/expected_group_labels', 'groups labeled as expected');
+unlink('labelled_groups_file');
+
+done_testing();
diff --git a/t/Bio/Roary/GroupStatistics.t b/t/Bio/Roary/GroupStatistics.t
new file mode 100755
index 0000000..9ea58be
--- /dev/null
+++ b/t/Bio/Roary/GroupStatistics.t
@@ -0,0 +1,79 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use Test::Files;
+
+BEGIN { unshift( @INC, './lib' ) }
+$ENV{PATH} .= ":./bin";
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::GroupStatistics');
+}
+
+my $annotate_groups = Bio::Roary::AnnotateGroups->new(
+ gff_files => ['t/data/query_1.gff','t/data/query_2.gff','t/data/query_3.gff'],
+ groups_filename => 't/data/query_groups',
+);
+
+my $analyse_groups = Bio::Roary::AnalyseGroups->new(
+ fasta_files => ['t/data/query_1.fa','t/data/query_2.fa','t/data/query_3.fa'],
+ groups_filename => 't/data/query_groups'
+);
+
+my $obj;
+
+ok($obj = Bio::Roary::GroupStatistics->new(
+ annotate_groups_obj => $annotate_groups,
+ analyse_groups_obj => $analyse_groups
+),'Initialise group statistics object');
+ok($obj->create_spreadsheet,'Create the CSV file');
+ok(-e 'gene_presence_absence.csv', 'CSV file exists');
+compare_ok('gene_presence_absence.csv','t/data/expected_group_statitics.csv', 'Spreadsheet content as expected');
+ok($obj->create_rtab,'Create the Rtab file');
+ok(-e 'gene_presence_absence.Rtab', 'Rtab file exists');
+compare_ok('gene_presence_absence.Rtab','t/data/expected_gene_presence_and_absence.Rtab', 'Rtab matrix content as expected');
+
+unlink('gene_presence_absence.csv');
+unlink('gene_presence_absence.Rtab');
+
+############################
+
+my $annotate_groups_2 = Bio::Roary::AnnotateGroups->new(
+ gff_files => ['t/data/query_1.gff','t/data/query_2.gff','t/data/query_3.gff','t/data/query_4_missing_genes.gff'],
+ groups_filename => 't/data/query_groups_missing_genes',
+);
+
+my $analyse_groups_2 = Bio::Roary::AnalyseGroups->new(
+ fasta_files => ['t/data/query_1.fa','t/data/query_2.fa','t/data/query_3.fa','t/data/query_4_missing_genes.fa'],
+ groups_filename => 't/data/query_groups_missing_genes'
+);
+
+ok($obj = Bio::Roary::GroupStatistics->new(
+ annotate_groups_obj => $annotate_groups_2,
+ analyse_groups_obj => $analyse_groups_2,
+ output_filename => 'missing_genes_stats.csv'
+),'Initialise group statistics object where one isolate has only 1 gene');
+ok($obj->create_spreadsheet,'Create the CSV file');
+ok(-e 'missing_genes_stats.csv', 'CSV file exists');
+compare_ok('missing_genes_stats.csv','t/data/expected_group_statitics_missing_genes.csv', 'Spreadsheet content as expected with missing genes');
+
+unlink('missing_genes_stats.csv');
+
+
+## TEST VERBOSE STATS ##
+
+ok($obj = Bio::Roary::GroupStatistics->new(
+ annotate_groups_obj => $annotate_groups,
+ analyse_groups_obj => $analyse_groups,
+ _verbose => 1,
+ output_filename => 'verbose_stats.csv'
+),'Initialise group statistics object');
+ok($obj->create_spreadsheet,'Create the CSV file');
+ok(-e 'verbose_stats.csv', 'CSV file exists');
+compare_ok('verbose_stats.csv','t/data/expected_group_statitics_verbose.csv', 'Verbose spreadsheet content as expected');
+
+unlink('verbose_stats.csv');
+
+done_testing();
diff --git a/t/Bio/Roary/InflateClusters.t b/t/Bio/Roary/InflateClusters.t
new file mode 100644
index 0000000..0a2826d
--- /dev/null
+++ b/t/Bio/Roary/InflateClusters.t
@@ -0,0 +1,40 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use Test::Files;
+
+BEGIN { unshift( @INC, './lib' ) }
+$ENV{PATH} .= ":./bin";
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::InflateClusters');
+}
+
+my $obj;
+
+
+ok( $obj = Bio::Roary::InflateClusters->new(
+ clusters_filename => 't/data/clustersfile',
+ mcl_filename => 't/data/mcl_file',
+ output_file => 'example.output'
+),'initialise object');
+ok($obj->inflate,'inflate the results');
+
+compare_ok('example.output','t/data/expected_inflated_results', 'inflated results as expected');
+unlink('example.output');
+
+
+ok( $obj = Bio::Roary::InflateClusters->new(
+ clusters_filename => 't/data/clusters_to_inflate',
+ mcl_filename => 't/data/clusters_to_inflate.mcl',
+ output_file => 'example.output'
+),'initialise object');
+ok($obj->inflate,'inflate the results');
+
+compare_ok('example.output','t/data/expected_clusters_to_inflate', 'inflated results as expected');
+unlink('example.output');
+
+done_testing();
+
diff --git a/t/Bio/Roary/OrderGenes.t b/t/Bio/Roary/OrderGenes.t
new file mode 100755
index 0000000..fb780fe
--- /dev/null
+++ b/t/Bio/Roary/OrderGenes.t
@@ -0,0 +1,148 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use File::Slurper 'read_text';
+use Test::Files;
+
+BEGIN { unshift( @INC, './lib' ) }
+$ENV{PATH} .= ":./bin";
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::OrderGenes');
+ use Bio::Roary::AnalyseGroups;
+}
+
+my $no_accessory_100 = order_genes_obj( 't/data/accessory_graphs/no_accessory', 1 );
+my $no_accessory_50 = order_genes_obj( 't/data/accessory_graphs/no_accessory', 0.5 );
+
+my $one_bubble_100 = order_genes_obj( 't/data/accessory_graphs/one_bubble', 1 );
+my $one_bubble_50 = order_genes_obj( 't/data/accessory_graphs/one_bubble', 0.5 );
+
+my $one_branch_100 = order_genes_obj( 't/data/accessory_graphs/one_branch', 1 );
+my $one_branch_50 = order_genes_obj( 't/data/accessory_graphs/one_branch', 0.5 );
+
+my $two_graphs_100 = order_genes_obj( 't/data/accessory_graphs/two_graphs', 1 );
+my $two_graphs_50 = order_genes_obj( 't/data/accessory_graphs/two_graphs', 0.5 );
+
+my $single_gene_100 = order_genes_obj( 't/data/accessory_graphs/single_gene_contig', 1 );
+my $single_gene_50 = order_genes_obj( 't/data/accessory_graphs/single_gene_contig', 0.5 );
+
+my $core_deletion_100 = order_genes_obj( 't/data/accessory_graphs/core_deletion', 1 );
+my $core_deletion_50 = order_genes_obj( 't/data/accessory_graphs/core_deletion', 0.5 );
+
+my $core_island_100 = order_genes_obj( 't/data/accessory_graphs/core_island', 1 );
+my $core_island_50 = order_genes_obj( 't/data/accessory_graphs/core_island', 0.5 );
+
+cleanup();
+my $analyse_groups = Bio::Roary::AnalyseGroups->new(
+ fasta_files => [ 't/data/accessory_graphs/file_1.fa', 't/data/accessory_graphs/file_2.fa', 't/data/accessory_graphs/file_3.fa' ],
+ groups_filename => 't/data/accessory_graphs/core_island'
+);
+
+ok(
+ my $obj = Bio::Roary::OrderGenes->new(
+ analyse_groups_obj => $analyse_groups,
+ gff_files => [ 't/data/accessory_graphs/file_1.gff', 't/data/accessory_graphs/file_2.gff', 't/data/accessory_graphs/file_3.gff' ],
+ core_definition => 1,
+ sample_weights => { 'file_1' => 0.5, 'file_2' => 1, 'file_3' => 0.1 }
+ ),
+ "Initialise order genes object for sample weights"
+);
+ok( $obj->groups_to_contigs, 'build the graph for sample weights' );
+ok( -e 'core_accessory_graph.dot', 'core accessory graph created for sample weights' );
+ok( -e 'accessory_graph.dot', 'accessory graph created for sample weights' );
+
+my $actual_graph = read_text('accessory_graph.dot');
+$actual_graph =~ s/group_[\w]/group_X/gi;
+is_deeply( $actual_graph, read_text('t/data/expected_sample_weights_accessory_graph.dot'), 'graph weights changed' );
+
+# Check how the final graphs get reordered.
+
+$obj = Bio::Roary::OrderGenes->new(
+ analyse_groups_obj => $analyse_groups,
+ gff_files => [ 't/data/accessory_graphs/file_1.gff', 't/data/accessory_graphs/file_2.gff', 't/data/accessory_graphs/file_3.gff' ],
+ core_definition => 1,
+ sample_weights => { 'file_1' => 0.5, 'file_2' => 1, 'file_3' => 0.1 },
+ samples_to_clusters => { 's1' => 'c1', 's2' => 'c1', 's3' => 'c2', 's4' => 'c2' },
+);
+
+my @paths_and_weights = (
+ {
+ path => [ 'g1', 'g2' ],
+ average_weight => 3,
+ sample_names => [ 's1', 's2' ]
+ },
+ {
+ path => [ 'g5', 'g6' ],
+ average_weight => 2,
+ sample_names => [ 's3', 's4' ]
+ },
+ {
+ path => [ 'g3', 'g4' ],
+ average_weight => 1,
+ sample_names => [ 's1', 's2' ]
+ }
+);
+my @expected_path_order = ( [ 'g1', 'g2' ], [ 'g3', 'g4' ], [ 'g5', 'g6' ] );
+is_deeply( $obj->_order_by_samples_and_weights( \@paths_and_weights ), \@expected_path_order, 'graphs reordered as expected' );
+
+cleanup();
+done_testing();
+
+sub order_genes_obj {
+ my ( $groups_filename, $core_definition ) = @_;
+
+ cleanup();
+ my $analyse_groups = Bio::Roary::AnalyseGroups->new(
+ fasta_files => [ 't/data/accessory_graphs/file_1.fa', 't/data/accessory_graphs/file_2.fa', 't/data/accessory_graphs/file_3.fa' ],
+ groups_filename => $groups_filename
+ );
+
+ ok(
+ my $obj = Bio::Roary::OrderGenes->new(
+ analyse_groups_obj => $analyse_groups,
+ gff_files =>
+ [ 't/data/accessory_graphs/file_1.gff', 't/data/accessory_graphs/file_2.gff', 't/data/accessory_graphs/file_3.gff' ],
+ core_definition => $core_definition
+ ),
+ "Initialise order genes object for $groups_filename"
+ );
+
+ ok( $obj->groups_to_contigs, 'build the graph' );
+ check_all_groups_in_output_graph( $groups_filename, $obj->groups_to_contigs, $core_definition );
+ ok( -e 'core_accessory_graph.dot', 'core accessory graph created' );
+ ok( -e 'accessory_graph.dot', 'accessory graph created' );
+
+ return $obj;
+}
+
+sub check_all_groups_in_output_graph {
+ my ( $groups_filename, $groups_to_contigs, $core_definition ) = @_;
+
+ open( my $groups_in, $groups_filename );
+ while (<$groups_in>) {
+ chomp;
+ my $line = $_;
+ next if ( $line eq '' );
+ my ( $group, $attributes ) = split( ':', $line );
+ ok( ( $groups_to_contigs->{$group} ), "group $group found in file $groups_filename" );
+
+ # Check to see if the accessory groups are tagged properly
+ $attributes =~ s/ //gi;
+ my @sequence_ids = split( /\t/, $attributes );
+ if ( @sequence_ids >= 3 * $core_definition ) {
+ ok( !defined( $groups_to_contigs->{$group}->{accessory_label} ), "group $group is core so shouldnt have any accessory labels" );
+ }
+ else {
+ ok( defined( $groups_to_contigs->{$group}->{accessory_label} ), "group $group is accessory so should have accessory label" );
+ }
+ }
+}
+
+sub cleanup {
+ unlink('core_accessory_graph.dot');
+ unlink('accessory_graph.dot');
+}
+
diff --git a/t/Bio/Roary/Output/CoreGeneAlignmentCoorindatesEMBL.t b/t/Bio/Roary/Output/CoreGeneAlignmentCoorindatesEMBL.t
new file mode 100644
index 0000000..43cde31
--- /dev/null
+++ b/t/Bio/Roary/Output/CoreGeneAlignmentCoorindatesEMBL.t
@@ -0,0 +1,42 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use Test::Files;
+
+BEGIN { unshift( @INC, './lib' ) }
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::Output::CoreGeneAlignmentCoordinatesEMBL');
+}
+
+ok(
+ my $core_gene_obj = Bio::Roary::Output::CoreGeneAlignmentCoordinatesEMBL->new(
+ multifasta_files => [
+ 't/data/multifasta_files/1.fa.aln', 't/data/multifasta_files/outof_order.fa.aln',
+ 't/data/multifasta_files/2.fa.aln', 't/data/multifasta_files/3.fa.aln'
+ ],
+ gene_lengths => {
+ 't/data/multifasta_files/1.fa.aln' => 1,
+ 't/data/multifasta_files/outof_order.fa.aln' => 10,
+ 't/data/multifasta_files/2.fa.aln' => 100,
+ 't/data/multifasta_files/3.fa.aln' => 1000
+ },
+ output_filename => 'output_name.embl'
+ ),
+ 'initialise core gene obj'
+);
+
+is('efg',$core_gene_obj->_gene_name_from_filename('t/abc/efg.fa.aln'), 'Get gene name with directory');
+is('efg',$core_gene_obj->_gene_name_from_filename('efg.fa.aln'), 'Get gene name with no directory');
+is('efg',$core_gene_obj->_gene_name_from_filename('efg'), 'Get gene name where theres no extension');
+is('efg',$core_gene_obj->_gene_name_from_filename('efg.fa'), 'Get gene name with partial extension');
+
+ok($core_gene_obj->create_file,'create the embl header file');
+compare_ok('output_name.embl', 't/data/multifasta_files/expected_output.embl', 'content of embl file as expected');
+
+is(1112,$core_gene_obj->_current_coordinate,'next coordinate');
+unlink('output_name.embl');
+
+done_testing();
diff --git a/t/Bio/Roary/Output/DifferenceBetweenSets.t b/t/Bio/Roary/Output/DifferenceBetweenSets.t
new file mode 100644
index 0000000..0b89164
--- /dev/null
+++ b/t/Bio/Roary/Output/DifferenceBetweenSets.t
@@ -0,0 +1,38 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use Moose;
+BEGIN { unshift( @INC, './t/lib' ) }
+with 'TestHelper';
+
+BEGIN { unshift( @INC, './lib' ) }
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::Output::DifferenceBetweenSets');
+}
+
+my $plot_groups_obj = Bio::Roary::AnalyseGroups->new(
+ fasta_files => [ 't/data/query_1.fa', 't/data/query_2.fa','t/data/query_3.fa' ],
+ groups_filename => 't/data/query_groups'
+);
+
+ok(my $obj = Bio::Roary::Output::DifferenceBetweenSets->new(
+ analyse_groups => $plot_groups_obj,
+ input_filenames_sets => [ ['t/data/query_1.fa'], ['t/data/query_2.fa','t/data/query_3.fa'] ]
+ ),'initialise set difference obj');
+
+ok($obj->groups_set_one_unique,'create set one unique');
+ok($obj->groups_set_two_unique,'create set two unique');
+ok($obj->groups_in_common,'create common set unique');
+
+compare_files('set_difference_unique_set_one','t/data/expected_set_difference_unique_set_one','set one file content as expected');
+compare_files('set_difference_unique_set_two','t/data/expected_set_difference_unique_set_two','set two file content as expected');
+compare_files('set_difference_common_set','t/data/expected_set_difference_common_set','common set file content as expected');
+
+unlink('set_difference_unique_set_one');
+unlink('set_difference_unique_set_two');
+unlink('set_difference_common_set');
+
+done_testing();
diff --git a/t/Bio/Roary/Output/GroupsMultifastaProtein.t b/t/Bio/Roary/Output/GroupsMultifastaProtein.t
new file mode 100644
index 0000000..0042990
--- /dev/null
+++ b/t/Bio/Roary/Output/GroupsMultifastaProtein.t
@@ -0,0 +1,26 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use Test::Files;
+
+BEGIN { unshift( @INC, './lib' ) }
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::Output::GroupsMultifastaProtein');
+}
+
+ok(
+ my $obj = Bio::Roary::Output::GroupsMultifastaProtein->new(
+ nucleotide_fasta_file => 't/data/nuc_multifasta.fa',
+ ),
+ 'initialise creating the nuc fasta obj'
+);
+ok($obj->convert_nucleotide_to_protein(),'perform the conversion');
+
+compare_ok('t/data/nuc_multifasta.faa', 't/data/expected_nuc_multifasta.faa', 'File content as expected');
+
+unlink('t/data/nuc_multifasta.faa');
+
+done_testing();
diff --git a/t/Bio/Roary/Output/GroupsMultifastas.t b/t/Bio/Roary/Output/GroupsMultifastas.t
new file mode 100755
index 0000000..ed3549c
--- /dev/null
+++ b/t/Bio/Roary/Output/GroupsMultifastas.t
@@ -0,0 +1,45 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use Test::Files;
+
+BEGIN { unshift( @INC, './lib' ) }
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::Output::GroupsMultifastas');
+}
+
+my $plot_groups_obj = Bio::Roary::AnalyseGroups->new(
+ fasta_files => [ 't/data/example_1.faa', 't/data/example_2.faa' ],
+ groups_filename => 't/data/example_groups'
+);
+
+ok(
+ my $obj = Bio::Roary::Output::GroupsMultifastas->new(
+ group_names => [ 'group_2', 'group_5' ],
+ analyse_groups => $plot_groups_obj
+ ),
+ 'initialise creating multiple fastas'
+);
+
+ok( $obj->create_files(), 'Create multiple fasta files' );
+
+# Check that the files have been created
+ok( -e $obj->output_filename_base . '_group_2.fa', $obj->output_filename_base . '_group_2.fa'.' group created' );
+ok( -e $obj->output_filename_base . '_group_5.fa', $obj->output_filename_base . '_group_2.fa'.' group created' );
+
+compare_ok( $obj->output_filename_base . '_group_2.fa' ,
+ 't/data/expected_output_groups_group_2_multi.fa',
+ 'group 2 contect as expected'
+);
+compare_ok( $obj->output_filename_base . '_group_5.fa' ,
+ 't/data/expected_output_groups_group_5_multi.fa',
+ 'group 5 contect as expected'
+);
+
+unlink( $obj->output_filename_base . '_group_2.fa' );
+unlink( $obj->output_filename_base . '_group_5.fa' );
+
+done_testing();
diff --git a/t/Bio/Roary/Output/GroupsMultifastasNucleotide.t b/t/Bio/Roary/Output/GroupsMultifastasNucleotide.t
new file mode 100644
index 0000000..2665b8e
--- /dev/null
+++ b/t/Bio/Roary/Output/GroupsMultifastasNucleotide.t
@@ -0,0 +1,91 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use File::Path qw( remove_tree);
+use Data::Dumper;
+use Test::Files;
+
+BEGIN { unshift( @INC, './lib' ) }
+
+BEGIN {
+ use Test::Most;
+ use Test::Output;
+ use_ok('Bio::Roary::Output::GroupsMultifastasNucleotide');
+ use Bio::Roary::AnnotateGroups;
+ use Bio::Roary::AnalyseGroups;
+
+}
+
+cleanup_files();
+my $gff_files = [ 't/data/query_1.gff', 't/data/query_2.gff','t/data/query_3.gff' ];
+
+my $obj;
+
+my $annotate_groups = Bio::Roary::AnnotateGroups->new(
+ gff_files => $gff_files,
+ groups_filename => 't/data/query_groups_reference',
+);
+
+ok($annotate_groups->reannotate);
+
+ok(
+ $obj = Bio::Roary::Output::GroupsMultifastasNucleotide->new(
+ group_names => [ 'group_2', 'group_5' ],
+ gff_files => $gff_files,
+ annotate_groups => $annotate_groups,
+ dont_delete_files => 1,
+ ),
+ 'initialise creating multiple fastas where you dont delete non core files'
+);
+ok( $obj->create_files(), 'Create multiple fasta files where you dont delete non core files' );
+
+compare_ok('pan_genome_sequences/hly.fa', 't/data/pan_genome_sequences/hly.fa', 'Check multifasta content is correct for 3-hly.fa');
+compare_ok('pan_genome_sequences/speH.fa','t/data/pan_genome_sequences/speH.fa','Check multifasta content is correct for 2-speH.fa');
+compare_ok('pan_genome_sequences/argF.fa','t/data/pan_genome_sequences/argF.fa','Check multifasta content is correct for 2-argF.fa');
+ok(-e 'pan_genome_reference.fa','pan genome reference file created');
+compare_ok('pan_genome_reference.fa', 't/data/expected_g2_g5_pan_genome_reference.fa', 'pan genome reference as expected');
+
+cleanup_files();
+
+
+ok(
+ $obj = Bio::Roary::Output::GroupsMultifastasNucleotide->new(
+ group_names => [ 'group_2', 'group_5' ],
+ gff_files => $gff_files,
+ annotate_groups => $annotate_groups,
+ dont_delete_files => 0,
+ ),
+ 'initialise creating multiple fastas where you delete non core files'
+);
+ok( $obj->create_files(), 'Create multiple fasta files where you delete non core files' );
+
+compare_ok('pan_genome_sequences/hly.fa', 't/data/pan_genome_sequences/hly.fa' , 'Check multifasta content is correct for 3-hly.fa ');
+ok(! -e 'pan_genome_sequences/speH.fa', 'Check 2-speH.fa doesnt exist since its non core');
+ok(! -e 'pan_genome_sequences/argF.fa', 'Check 2-argF.fa doesnt exist since its non core');
+cleanup_files();
+
+
+
+# test group number limit
+ok(
+ $obj = Bio::Roary::Output::GroupsMultifastasNucleotide->new(
+ group_names => [ 'group_2', 'group_5' ],
+ gff_files => $gff_files,
+ annotate_groups => $annotate_groups,
+ group_limit => 4
+ ),
+ 'initialise creating multiple fastas'
+);
+my $exp_stderr = "Number of clusters (8) exceeds limit (4). Multifastas not created. Please check the spreadsheet for contamination from different species or increase the --group_limit parameter.\n";
+stderr_is { $obj->create_files() } $exp_stderr, 'multifasta creation fails when group limit exceeded';
+
+cleanup_files();
+
+done_testing();
+
+
+sub cleanup_files {
+ remove_tree('pan_genome_sequences');
+ unlink('reannotated_groups_file');
+ unlink('pan_genome_reference.fa');
+}
\ No newline at end of file
diff --git a/t/Bio/Roary/Output/NumberOfGroups.t b/t/Bio/Roary/Output/NumberOfGroups.t
new file mode 100644
index 0000000..549a620
--- /dev/null
+++ b/t/Bio/Roary/Output/NumberOfGroups.t
@@ -0,0 +1,71 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use Test::Files;
+
+BEGIN { unshift( @INC, './lib' ) }
+
+BEGIN {
+ use Test::Most;
+ use Bio::Roary::AnnotateGroups;
+ use Bio::Roary::AnalyseGroups;
+ use Bio::Roary::GroupStatistics;
+ use_ok('Bio::Roary::Output::NumberOfGroups');
+}
+
+my $annotate_groups = Bio::Roary::AnnotateGroups->new(
+ gff_files => ['t/data/query_1.gff','t/data/query_2.gff','t/data/query_3.gff'],
+ groups_filename => 't/data/query_groups',
+);
+
+my $analyse_groups = Bio::Roary::AnalyseGroups->new(
+ fasta_files => ['t/data/query_1.fa','t/data/query_2.fa','t/data/query_3.fa'],
+ groups_filename => 't/data/query_groups'
+);
+
+my $group_statistics = Bio::Roary::GroupStatistics->new(
+ annotate_groups_obj => $annotate_groups,
+ analyse_groups_obj => $analyse_groups
+);
+
+ok(my $obj = Bio::Roary::Output::NumberOfGroups->new(
+ group_statistics_obj => $group_statistics,
+ annotate_groups_obj => $annotate_groups
+ ),'initialise object');
+
+ok($obj->create_output_files, 'create the raw output file');
+
+ok(-e 'number_of_conserved_genes.Rtab', 'check raw output file created');
+compare_ok('t/data/expected_number_of_conserved_genes.tab', 'number_of_conserved_genes.Rtab', 'Content of total groups tab file as expected');
+unlink('number_of_conserved_genes.Rtab');
+
+ok(-e 'number_of_new_genes.Rtab', 'check raw output file created');
+compare_ok('t/data/expected_number_of_new_genes.tab', 'number_of_new_genes.Rtab', '');
+unlink('number_of_new_genes.Rtab');
+
+ok(-e 'number_of_genes_in_pan_genome.Rtab', 'check raw output file created');
+compare_ok('t/data/expected_number_of_genes_in_pan_genome.tab', 'number_of_genes_in_pan_genome.Rtab', 'Content of total groups tab file as expected');
+unlink('number_of_genes_in_pan_genome.Rtab');
+
+ok(-e 'number_of_unique_genes.Rtab', 'check raw output file created');
+compare_ok('t/data/expected_number_of_unique_genes.tab', 'number_of_unique_genes.Rtab', 'Content of unique groups tab file as expected');
+unlink('number_of_unique_genes.Rtab');
+
+
+# Vary the core
+ok($obj = Bio::Roary::Output::NumberOfGroups->new(
+ group_statistics_obj => $group_statistics,
+ annotate_groups_obj => $annotate_groups,
+ core_definition => 0.6
+ ),"initialise object with 60 percent core definition");
+ok($obj->create_output_files, 'create the raw output files for 60 percent core def');
+compare_ok('t/data/expected_number_of_conserved_genes_0.6.tab','number_of_conserved_genes.Rtab', 'Content of conserved genes with 60 percent core def');
+
+unlink('number_of_conserved_genes.Rtab');
+unlink('number_of_new_genes.Rtab');
+unlink('number_of_genes_in_pan_genome.Rtab');
+unlink('number_of_unique_genes.Rtab');
+unlink('group_statitics.csv');
+
+done_testing();
diff --git a/t/Bio/Roary/Output/QueryGroups.t b/t/Bio/Roary/Output/QueryGroups.t
new file mode 100755
index 0000000..dbc78e9
--- /dev/null
+++ b/t/Bio/Roary/Output/QueryGroups.t
@@ -0,0 +1,73 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use Moose;
+BEGIN { unshift( @INC, './t/lib' ) }
+with 'TestHelper';
+
+BEGIN { unshift( @INC, './lib' ) }
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::Output::QueryGroups');
+}
+
+my $plot_groups_obj = Bio::Roary::AnalyseGroups->new(
+ fasta_files => [ 't/data/query_1.fa', 't/data/query_2.fa','t/data/query_3.fa' ],
+ groups_filename => 't/data/query_groups'
+);
+
+my $obj;
+ok($obj = Bio::Roary::Output::QueryGroups->new(
+ analyse_groups => $plot_groups_obj,
+ input_filenames => [ 't/data/query_1.fa', 't/data/query_2.fa','t/data/query_3.fa' ]
+ ),'initialise groups query object');
+
+ok($obj->groups_union(), 'create the union file');
+ok($obj->groups_intersection(), 'create the intersection file');
+ok($obj->groups_complement(), 'create the complement file');
+
+compare_files('union_of_groups.gg','t/data/expected_union_of_groups.gg', 'contents of the union groups as expected');
+compare_files('intersection_of_groups.gg', 't/data/expected_intersection_of_groups.gg', 'contents of the intersection groups as expected');
+compare_files('complement_of_groups.gg', 't/data/expected_complement_of_groups.gg', 'contents of the complement groups as expected');
+
+######################################
+# test varying core definition
+ok($obj = Bio::Roary::Output::QueryGroups->new(
+ analyse_groups => $plot_groups_obj,
+ input_filenames => [ 't/data/query_1.fa', 't/data/query_2.fa','t/data/query_3.fa' ],
+ core_definition => 0.66
+ ),'initialise groups query object');
+
+ok($obj->groups_intersection(), 'create the intersection file');
+ok($obj->groups_complement(), 'create the complement file');
+
+compare_files('intersection_of_groups.gg', 't/data/expected_intersection_of_groups_core0.66.gg', 'contents of the intersection groups as expected');
+compare_files('complement_of_groups.gg', 't/data/expected_complement_of_groups_core0.66.gg', 'contents of the complement groups as expected');
+
+
+unlink('union_of_groups.gg');
+unlink('intersection_of_groups.gg');
+unlink('complement_of_groups.gg');
+
+######################################
+
+$plot_groups_obj = Bio::Roary::AnalyseGroups->new(
+ fasta_files => [ 't/data/query_1.fa', 't/data/query_2.fa','t/data/query_3.fa' ],
+ groups_filename => 't/data/query_groups_paralogs'
+);
+
+ok($obj = Bio::Roary::Output::QueryGroups->new(
+ analyse_groups => $plot_groups_obj,
+ input_filenames => [ 't/data/query_1.fa', 't/data/query_2.fa','t/data/query_3.fa' ]
+ ),'initialise groups query object with paralogs');
+
+ok($obj->groups_intersection(), 'create the intersection file');
+
+compare_files('intersection_of_groups.gg', 't/data/expected_intersection_of_groups_paralogs.gg', 'contents of the intersection groups with paralogs as expected');
+unlink('intersection_of_groups.gg');
+
+
+done_testing();
+
diff --git a/t/Bio/Roary/ParallelAllAgainstAllBlast.t b/t/Bio/Roary/ParallelAllAgainstAllBlast.t
new file mode 100644
index 0000000..7ffb0ca
--- /dev/null
+++ b/t/Bio/Roary/ParallelAllAgainstAllBlast.t
@@ -0,0 +1,30 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use Cwd;
+
+BEGIN { unshift( @INC, './lib' ) }
+$ENV{PATH} .= ":./bin";
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::ParallelAllAgainstAllBlast');
+}
+my $obj;
+my $cwd = getcwd();
+
+ok($obj = Bio::Roary::ParallelAllAgainstAllBlast->new(
+ fasta_file => 't/data/example_1.faa',
+ blastp_exec => $cwd.'/t/bin/dummy_blastp',
+ makeblastdb_exec => $cwd.'/t/bin/dummy_makeblastdb',
+),'initialise obj with mocked external applications');
+ok($obj->run(),'Run locally');
+ok(-e $obj->_working_directory_name.'/blast_results', 'Combined blast results');
+
+unlink('output_contigs.phr');
+unlink('output_contigs.pin');
+unlink('output_contigs.psq');
+unlink('results.out');
+
+done_testing();
diff --git a/t/Bio/Roary/PrepareInputFiles.t b/t/Bio/Roary/PrepareInputFiles.t
new file mode 100644
index 0000000..8bccdae
--- /dev/null
+++ b/t/Bio/Roary/PrepareInputFiles.t
@@ -0,0 +1,56 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use File::Basename;
+
+BEGIN { unshift( @INC, './lib' ) }
+$ENV{PATH} .= ":./bin";
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::PrepareInputFiles');
+}
+
+my $obj;
+
+ok(
+ $obj = Bio::Roary::PrepareInputFiles->new(
+ input_files => [
+ 't/data/example_annotation.gff', 't/data/example_1.faa',
+ 't/data/example_annotation_2.gff', 't/data/example_2.faa','t/data/sequences_with_unknowns.faa'
+ ],
+ ),
+ 'initalise'
+);
+
+my @sorted_fasta_files = sort map { basename($_) } sort @{$obj->fasta_files};
+my @expected_fasta_files = sort((
+ 'example_1.faa.tmp.filtered.fa',
+ 'example_2.faa.tmp.filtered.fa',
+ 'example_annotation.gff.proteome.faa',
+ 'example_annotation_2.gff.proteome.faa',
+ 'sequences_with_unknowns.faa.tmp.filtered.fa'
+));
+
+is_deeply(
+ \@sorted_fasta_files,
+ \@expected_fasta_files,
+ 'proteome extracted from gff files, input fasta files filtered'
+);
+
+my @input_files_lookup = sort map { basename($_) } @{$obj->lookup_fasta_files_from_unknown_input_files( [ 't/data/example_annotation_2.gff', 't/data/example_1.faa' ] )};
+is_deeply(
+ \@input_files_lookup,
+ ['example_1.faa.tmp.filtered.fa','example_annotation_2.gff.proteome.faa'],
+ 'previously created faa file looked up from gff filename'
+);
+
+unlink('example_annotation.gff.proteome.faa');
+unlink('example_annotation_2.gff.proteome.faa');
+unlink('sequences_with_unknowns.faa.tmp.filtered.fa');
+unlink('example_1.faa.tmp.filtered.fa');
+unlink('example_2.faa.tmp.filtered.fa');
+
+done_testing();
+
diff --git a/t/Bio/Roary/PresenceAbsenceMatrix.t b/t/Bio/Roary/PresenceAbsenceMatrix.t
new file mode 100644
index 0000000..022656b
--- /dev/null
+++ b/t/Bio/Roary/PresenceAbsenceMatrix.t
@@ -0,0 +1,97 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use Test::Files;
+
+BEGIN { unshift( @INC, './lib' ) }
+$ENV{PATH} .= ":./bin";
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::PresenceAbsenceMatrix');
+ use Bio::Roary::AnnotateGroups;
+}
+my $obj;
+my $annotate_groups = Bio::Roary::AnnotateGroups->new(
+ gff_files => [ 't/data/query_1.gff', 't/data/query_2.gff', 't/data/query_3.gff' ],
+ groups_filename => 't/data/query_groups',
+);
+
+my $sorted_file_names = [ 't/data/query_1.fa', 't/data/query_2.fa', 't/data/query_3.fa' ];
+my $groups_to_files = {
+ 'group_3' => {
+ 't/data/query_1.fa' => [ '1_3' ],
+ 't/data/query_3.fa' => [ '3_3' ]
+ },
+ 'group_5' => {
+ 't/data/query_3.fa' => [ '3_5' ]
+ },
+ 'group_7' => {
+ 't/data/query_2.fa' => [ '2_7' ]
+ },
+ 'group_4' => {
+ 't/data/query_3.fa' => [ '3_4' ],
+ 't/data/query_2.fa' => [ '2_4' ]
+ },
+ 'group_1' => {
+ 't/data/query_1.fa' => [ '1_1' ],
+ 't/data/query_3.fa' => [ '3_1' ],
+ 't/data/query_2.fa' => [ '2_1' ]
+ },
+ 'group_6' => {
+ 't/data/query_1.fa' => [ '1_6' ]
+ },
+ 'group_2' => {
+ 't/data/query_1.fa' => [ '1_2' ],
+ 't/data/query_2.fa' => [ '2_2' ]
+ }
+};
+my $num_files_in_groups = {
+ 'group_3' => 2,
+ 'group_5' => 1,
+ 'group_7' => 1,
+ 'group_4' => 2,
+ 'group_1' => 3,
+ 'group_6' => 1,
+ 'group_2' => 2
+};
+my $sample_headers = [ 'query_1.fa', 'query_2.fa', 'query_3.fa' ];
+
+ok(
+ $obj = Bio::Roary::PresenceAbsenceMatrix->new(
+ annotate_groups_obj => $annotate_groups,
+ output_filename => 'test_gene_presence_absence.Rtab',
+ sorted_file_names => $sorted_file_names,
+ groups_to_files => $groups_to_files,
+ num_files_in_groups => $num_files_in_groups,
+ sample_headers => $sample_headers,
+ ),
+ 'initialise object'
+);
+
+ok( $obj->create_matrix_file, 'create matrix file' );
+ok( -e 'test_gene_presence_absence.Rtab', 'matrix file exists' );
+compare_ok( 'test_gene_presence_absence.Rtab', 't/data/expected_gene_presence_and_absence.Rtab', 'Rtab matrix content as expected' );
+
+# one gene one group
+$groups_to_files = {'group_1' => {'t/data/query_1.fa' => [ '1_1' ]}};
+$num_files_in_groups = {'group_1' => 1};
+
+ok(
+ $obj = Bio::Roary::PresenceAbsenceMatrix->new(
+ annotate_groups_obj => $annotate_groups,
+ output_filename => 'test_gene_presence_absence.Rtab',
+ sorted_file_names => $sorted_file_names,
+ groups_to_files => $groups_to_files,
+ num_files_in_groups => $num_files_in_groups,
+ sample_headers => $sample_headers,
+ ),
+ 'initialise object one gene one group'
+);
+
+ok( $obj->create_matrix_file, 'create matrix file one gene one group' );
+compare_ok( 'test_gene_presence_absence.Rtab', 't/data/expected_one_gene_presence_and_absence.Rtab', 'Rtab matrix content as expected for one gene one group' );
+
+unlink('test_gene_presence_absence.Rtab');
+done_testing();
diff --git a/t/Bio/Roary/QC/Report.t b/t/Bio/Roary/QC/Report.t
new file mode 100755
index 0000000..4ff288c
--- /dev/null
+++ b/t/Bio/Roary/QC/Report.t
@@ -0,0 +1,100 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use Test::Files;
+use File::Which;
+
+BEGIN { unshift( @INC, './lib' ) }
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::QC::Report');
+}
+
+
+
+my $kraken_data = [
+ [ 'assembly1', 'Clostridium', 'Clostridium difficile' ],
+ [ 'assembly2', 'Escherichia', 'Escherichia coli' ],
+ [ 'assembly3', 'Streptococcus', 'Streptococcus pneumoniae' ]
+];
+
+ok(
+ my $qc_report_obj = Bio::Roary::QC::Report->new(
+ input_files => [],
+ outfile => "kraken_report.csv",
+ _kraken_data => $kraken_data,
+ kraken_db => 't/data/kraken_test/',
+ job_runner => "Local"
+ ),
+ 'QC report object created with no input gff files'
+);
+
+ok( $qc_report_obj->report, 'report generated' );
+ok( -e 'kraken_report.csv', 'report file exists' );
+
+compare_ok('kraken_report.csv',"t/data/exp_qc_report.csv", 'report file correct' );
+
+unlink('kraken_report.csv');
+
+
+ok(
+ $qc_report_obj = Bio::Roary::QC::Report->new(
+ input_files => [ 't/data/query_1.gff', 't/data/query_2.gff' ],
+ outfile => "kraken_report.csv",
+ job_runner => "Local",
+ kraken_db => 't/data/kraken_test/',
+ verbose => 0,
+ ),
+ 'QC report object created with data'
+);
+
+is( $qc_report_obj->_tmp_directory . '/abc.fna', $qc_report_obj->_nuc_fasta_filename('abc.gff'), 'filename of nuc from gff' );
+is(
+ 'sed -n \'/##FASTA/,//p\' abc.gff | grep -v \'##FASTA\' > ' . $qc_report_obj->_tmp_directory . '/abc.fna',
+ $qc_report_obj->_extract_nuc_fasta_cmd('abc.gff'),
+ 'extract nuc command'
+);
+
+ok( my $nuc_files = $qc_report_obj->_extract_nuc_files_from_all_gffs(), 'extract nuc files from gffs' );
+
+is_deeply( [ $qc_report_obj->_tmp_directory . '/query_1.fna', $qc_report_obj->_tmp_directory . '/query_2.fna' ],
+ $nuc_files, 'check extracted nuc files from gffs list' );
+
+compare_ok( $qc_report_obj->_tmp_directory . '/query_1.fna' ,
+ 't/data/expected_query_1.fna',
+ 'Check FASTA file 1 extracted as expected'
+);
+compare_ok( $qc_report_obj->_tmp_directory . '/query_2.fna' ,
+ 't/data/expected_query_2.fna',
+ 'Check FASTA file 2 extracted as expected'
+);
+
+SKIP:
+{
+
+ skip "kraken not installed", 2 unless ( which('kraken') );
+ skip "kraken-report not installed", 2 unless ( which('kraken-report') );
+
+ ok( my $kraken_files = $qc_report_obj->_run_kraken_on_nuc_files($nuc_files), 'run kraken over everything' );
+ is_deeply( [ $qc_report_obj->_tmp_directory . '/query_1.kraken', $qc_report_obj->_tmp_directory . '/query_2.kraken' ],
+ $kraken_files, 'check kraken files are created from nuc files' );
+
+ ok(my $kraken_report_files = $qc_report_obj->_run_kraken_report_on_kraken_files( $kraken_files ), 'build reports');
+ is_deeply( [ $qc_report_obj->_tmp_directory . '/query_1.kraken.report', $qc_report_obj->_tmp_directory . '/query_2.kraken.report' ],
+ $kraken_report_files, 'check kraken report files are created from kraken files' );
+
+ is_deeply([['query_1','Staphylococcus', 'Staphylococcus aureus'],['query_2','Staphylococcus', 'Staphylococcus aureus']],$qc_report_obj->_parse_kraken_reports($kraken_report_files),'check output report');
+
+
+ ok( $qc_report_obj->report, 'report generated with real data' );
+ ok( -e 'kraken_report.csv', 'report file exists with real data' );
+ compare_ok('kraken_report.csv',"t/data/exp_qc_report_real.csv", 'report file correct' );
+ unlink('kraken_report.csv');
+
+}
+
+
+done_testing();
+
diff --git a/t/Bio/Roary/ReformatInputGFFs.t b/t/Bio/Roary/ReformatInputGFFs.t
new file mode 100755
index 0000000..16ad53b
--- /dev/null
+++ b/t/Bio/Roary/ReformatInputGFFs.t
@@ -0,0 +1,69 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use File::Path qw(remove_tree);
+use Test::Files;
+
+BEGIN { unshift( @INC, './lib' ) }
+$ENV{PATH} .= ":./bin";
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::ReformatInputGFFs');
+}
+
+
+my $obj;
+remove_tree('fixed_input_files');
+ok($obj = Bio::Roary::ReformatInputGFFs->new(gff_files => ['t/data/reformat_input_gffs/query_1.gff']), 'initialise with one input gff');
+ok($obj->fix_duplicate_gene_ids, 'fix duplicates with one input gff');
+is_deeply($obj->fixed_gff_files, ['t/data/reformat_input_gffs/query_1.gff'] ,'list of gff files with one input gff, nothing should change');
+ok(!( -d 'fixed_input_files'), 'Directory shouldnt exist because there arent any fixed input files');
+
+
+ok($obj = Bio::Roary::ReformatInputGFFs->new(gff_files => ['t/data/reformat_input_gffs/query_1.gff', 't/data/reformat_input_gffs/query_2.gff',]), 'initialise with 2 input gffs');
+ok(!( -d 'fixed_input_files'), 'Directory shouldnt exist before running');
+is_deeply($obj->_get_ids_for_gff_file('t/data/reformat_input_gffs/query_1.gff'),[
+ '1_1',
+ 'abc_00002',
+ 'abc_00003',
+ 'abc_00004',
+ '1_2'
+ ],'extract ids');
+is_deeply($obj->_get_ids_for_gff_file('t/data/reformat_input_gffs/query_2.gff'),[
+ '1_1',
+ 'abc_00002',
+ 'abc_00003',
+ 'abc_00004',
+ '1_2'
+ ],'extract ids');
+ok($obj->fix_duplicate_gene_ids, 'fix duplicates with 2 input gffs');
+ok(( -d 'fixed_input_files'), 'Directory should exist because there is one gff thats fixed');
+is_deeply($obj->fixed_gff_files, ['t/data/reformat_input_gffs/query_1.gff','fixed_input_files/query_2.gff' ] ,'list of gff files one in the fixed directory');
+ok(( -e 'fixed_input_files/query_2.gff'), 'fixed file should exist');
+compare_ok('fixed_input_files/query_2.gff', 't/data/reformat_input_gffs/expected_fixed_query_2.gff', 'fixed file should have expected changes');
+remove_tree('fixed_input_files');
+
+
+ok($obj = Bio::Roary::ReformatInputGFFs->new(gff_files => ['t/data/reformat_input_gffs/query_1.gff', 't/data/reformat_input_gffs/query_2.gff', 't/data/reformat_input_gffs/query_3.gff']), 'initialise with 3 input gffs');
+ok(!( -d 'fixed_input_files'), 'Directory shouldnt exist before running');
+ok($obj->fix_duplicate_gene_ids, 'fix duplicates with 3 input gffs');
+ok(( -d 'fixed_input_files'), 'Directory should exist because there is 2 gffs thats fixed');
+is_deeply($obj->fixed_gff_files, ['t/data/reformat_input_gffs/query_1.gff','fixed_input_files/query_2.gff','fixed_input_files/query_3.gff' ] ,'list of gff files 2 in the fixed directory');
+ok(( -e 'fixed_input_files/query_2.gff'), 'fixed file should exist');
+ok(( -e 'fixed_input_files/query_3.gff'), 'fixed file should exist');
+compare_ok('fixed_input_files/query_2.gff','t/data/reformat_input_gffs/expected_fixed_query_2.gff', 'fixed file should have expected changes');
+compare_ok('fixed_input_files/query_3.gff', 't/data/reformat_input_gffs/expected_fixed_query_3.gff', 'fixed file should have expected changes');
+remove_tree('fixed_input_files');
+
+
+ok($obj = Bio::Roary::ReformatInputGFFs->new(gff_files => ['t/data/reformat_input_gffs/real_1.gff']), 'initialise with 1 gff that has shown to have a bug');
+ok(my $fixed_file = $obj->_add_suffix_to_gene_ids_and_return_new_file('t/data/reformat_input_gffs/real_1.gff'), 'fix duplicates');
+ok(( -e 'fixed_input_files/real_1.gff'), 'fixed file should exist');
+compare_ok('fixed_input_files/real_1.gff', 't/data/reformat_input_gffs/expected_real_1.gff', 'fixed file should have expected changes');
+remove_tree('fixed_input_files');
+
+
+done_testing();
+
diff --git a/t/Bio/Roary/ReorderSpreadsheet.t b/t/Bio/Roary/ReorderSpreadsheet.t
new file mode 100644
index 0000000..d080bca
--- /dev/null
+++ b/t/Bio/Roary/ReorderSpreadsheet.t
@@ -0,0 +1,36 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use Test::Files;
+
+BEGIN { unshift( @INC, './lib' ) }
+$ENV{PATH} .= ":./bin";
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::ReorderSpreadsheet');
+}
+
+ok(
+ my $obj = Bio::Roary::ReorderSpreadsheet->new(
+ tree_file => 't/data/reorder_isolates.tre',
+ spreadsheet => 't/data/reorder_isolates_input.csv',
+ output_filename => 'reorder_isolates_output.csv',
+ sortby => 'height'
+ ),
+ 'initialise reordering the spreadsheet'
+);
+
+is_deeply($obj->_column_mappings,[0,1,2,3,4,5,6,7,8,9,10,11,12,13],'Column mappings with fixed in same order and end columns ordered by tree file');
+ok( $obj->reorder_spreadsheet(), 'run the reorder method' );
+ok( -e $obj->output_filename, 'check the output file exists' );
+
+compare_ok('t/data/reorder_isolates_expected_output.csv',
+ 'reorder_isolates_output.csv',
+ 'content of the spreadsheet as expected'
+);
+
+unlink('reorder_isolates_output.csv');
+
+done_testing();
diff --git a/t/Bio/Roary/SampleOrder.t b/t/Bio/Roary/SampleOrder.t
new file mode 100644
index 0000000..4a20faa
--- /dev/null
+++ b/t/Bio/Roary/SampleOrder.t
@@ -0,0 +1,164 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+
+BEGIN { unshift( @INC, './lib' ) }
+$ENV{PATH} .= ":./bin";
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::SampleOrder');
+}
+
+ok(my $obj = Bio::Roary::SampleOrder->new(
+ tree_file => 't/data/reorder_isolates.tre',
+ ), 'initialise sample order object');
+
+is_deeply($obj->ordered_samples(),['query_1', 'query_3','query_4','query_2'],'order of sample names matches the tree');
+
+ok( $obj = Bio::Roary::SampleOrder->new(
+ tree_file => 't/data/raxml.tre',
+ ), 'initialise sample order object with raxml tree');
+
+is_deeply($obj->ordered_samples(),[
+ 'efgh_7#3',
+ 'abcd_4#15',
+ 'abcd_3#9',
+ 'abcd_4#17',
+ 'abcd_3#20',
+ 'abcd_3#96',
+ 'abcd_3#7',
+ '6753_5#30',
+ 'abcd_3#8',
+ 'abcd_3#12',
+ 'abcd_4#13',
+ 'abcd_3#4',
+ 'abcd_3#47',
+ 'abcd_4#36',
+ 'abcd_3#90',
+ 'abcd_3#45',
+ 'abcd_3#51',
+ 'abcd_3#76',
+ 'abcd_4#22',
+ 'abcd_3#94',
+ 'abcd_3#72',
+ 'abcd_3#18',
+ 'abcd_3#82',
+ 'abcd_3#88',
+ 'abcd_3#87',
+ 'abcd_3#58',
+ 'abcd_3#85',
+ 'abcd_4#24',
+ 'abcd_3#86',
+ 'abcd_4#38',
+ 'abcd_3#70',
+ 'abcd_3#89',
+ 'abcd_3#19',
+ 'abcd_3#84',
+ 'abcd_3#60',
+ 'abcd_4#21',
+ 'abcd_3#35',
+ 'abcd_3#32',
+ 'abcd_4#20',
+ 'abcd_3#11',
+ 'abcd_4#28',
+ 'abcd_4#27',
+ 'abcd_3#54',
+ 'abcd_3#53',
+ 'abcd_3#43',
+ 'abcd_3#50',
+ 'abcd_4#12',
+ 'abcd_3#15',
+ 'abcd_3#21',
+ 'abcd_3#91',
+ 'abcd_3#73',
+ 'abcd_3#61',
+ 'abcd_4#35',
+ 'abcd_3#17',
+ 'abcd_3#67',
+ 'abcd_3#27',
+ 'abcd_3#13',
+ 'abcd_3#24',
+ 'abcd_3#95',
+ 'abcd_3#23',
+ 'abcd_3#29',
+ 'abcd_3#75',
+ 'abcd_3#25',
+ 'abcd_4#16',
+ 'abcd_4#30',
+ 'abcd_4#26',
+ 'abcd_3#36',
+ 'abcd_4#25',
+ 'abcd_3#64',
+ 'abcd_3#44',
+ 'abcd_3#68',
+ 'abcd_3#69',
+ 'efgh_7#12',
+ 'abcd_3#55',
+ 'abcd_4#1',
+ 'abcd_3#56',
+ 'abcd_3#14',
+ 'abcd_4#7',
+ 'abcd_4#8',
+ 'abcd_3#26',
+ 'abcd_4#9',
+ 'abcd_4#40',
+ 'abcd_4#10',
+ 'abcd_4#6',
+ 'abcd_4#5',
+ 'abcd_3#3',
+ 'abcd_3#33',
+ 'abcd_3#28',
+ 'abcd_3#6',
+ 'abcd_3#16',
+ 'abcd_3#79',
+ 'abcd_3#77',
+ 'abcd_4#41',
+ 'abcd_4#34',
+ 'abcd_3#5',
+ 'abcd_3#74',
+ 'abcd_3#34',
+ 'abcd_3#2',
+ 'abcd_3#22',
+ 'abcd_4#32',
+ 'abcd_3#92',
+ 'abcd_4#19',
+ 'abcd_4#23',
+ 'abcd_4#18',
+ 'abcd_3#37',
+ 'abcd_3#59',
+ 'abcd_3#30',
+ 'abcd_3#1',
+ 'abcd_4#42',
+ 'abcd_3#10',
+ 'abcd_4#37',
+ 'abcd_3#81',
+ 'abcd_3#80',
+ 'abcd_3#83',
+ 'abcd_4#33',
+ 'abcd_4#31',
+ 'abcd_3#71',
+ 'abcd_3#78',
+ 'abcd_4#39',
+ 'abcd_3#41',
+ 'abcd_4#29',
+ 'abcd_4#14',
+ 'abcd_3#31',
+ 'abcd_3#93',
+ 'abcd_3#62',
+ 'abcd_3#48',
+ 'abcd_3#42',
+ 'abcd_3#52',
+ 'abcd_3#57',
+ 'abcd_3#49',
+ 'abcd_4#3',
+ 'abcd_4#2',
+ 'abcd_3#39',
+ 'abcd_3#38',
+ 'abcd_4#11',
+ '5749_2#1'
+ ],'order of sample names matches the raxml tree');
+
+
+done_testing();
diff --git a/t/Bio/Roary/SequenceLengths.t b/t/Bio/Roary/SequenceLengths.t
new file mode 100644
index 0000000..15acd8f
--- /dev/null
+++ b/t/Bio/Roary/SequenceLengths.t
@@ -0,0 +1,34 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+
+BEGIN { unshift( @INC, './lib' ) }
+$ENV{PATH} .= ":./bin";
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::SequenceLengths');
+}
+
+ok(
+ my $obj = Bio::Roary::SequenceLengths->new(
+ fasta_file => 't/data/example_1.faa',
+ ),
+ 'Initialise object'
+);
+
+is_deeply(
+ $obj->sequence_lengths,
+ {
+ '1234#10_00006' => 211,
+ '1234#10_00003' => 113,
+ '1234#10_00001' => 145,
+ '1234#10_00005' => 207,
+ '1234#10_00002' => 246,
+ '1234#10_00007' => 242
+ },
+ 'hash with lengths of each sequence'
+);
+
+done_testing();
diff --git a/t/Bio/Roary/SortFasta.t b/t/Bio/Roary/SortFasta.t
new file mode 100755
index 0000000..3450084
--- /dev/null
+++ b/t/Bio/Roary/SortFasta.t
@@ -0,0 +1,58 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use Test::Files;
+
+BEGIN { unshift( @INC, './lib' ) }
+$ENV{PATH} .= ":./bin";
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::SortFasta');
+}
+
+my $obj;
+
+
+ok( $obj = Bio::Roary::SortFasta->new(
+ input_filename => 't/data/out_of_order_fasta.fa',
+), 'initalise object');
+
+
+ok($obj->sort_fasta, 'sort the fasta file');
+ok(-e 't/data/out_of_order_fasta.fa.sorted.fa', 'the new file exists');
+
+compare_ok('t/data/out_of_order_fasta.fa.sorted.fa', 't/data/expected_out_of_order_fasta.fa.sorted.fa', 'check order of sorted fasta');
+
+
+ok( $obj = Bio::Roary::SortFasta->new(
+ input_filename => 't/data/uneven_sequences.fa',
+ make_multiple_of_three => 1,
+), 'initalise object with uneven sequences');
+
+ok($obj->sort_fasta, 'sort the fasta file');
+compare_ok($obj->output_filename, 't/data/expected_uneven_sequences.fa', "output sequences are now divisible by three");
+
+ok( $obj = Bio::Roary::SortFasta->new(
+ input_filename => 't/data/nnn_at_end.fa',
+ remove_nnn_from_end => 1,
+), 'initalise object with alignment with nnn at end ');
+ok($obj->sort_fasta, 'sort the fasta file and remove nnn at end');
+compare_ok($obj->output_filename, 't/data/expected_nnn_at_end.fa', "output sequences are now divisible by three");
+
+ok( $obj = Bio::Roary::SortFasta->new(
+ input_filename => 't/data/uneven_sequences.fa',
+ make_multiple_of_three => 1,
+ remove_nnn_from_end => 1,
+), 'initalise object with uneven sequences and remove nnn from end but nothing to remove');
+ok($obj->sort_fasta, 'sort the fasta file');
+compare_ok($obj->output_filename, 't/data/expected_uneven_sequences.fa', "output sequences are now divisible by three and no nnn removed");
+
+
+is(0,$obj->_percentage_similarity("AAA","BBB"), 'totally different');
+is(1,$obj->_percentage_similarity("AAA","AAA"), 'all the same');
+is(0.5,$obj->_percentage_similarity("AAAA","AABB"), 'half different');
+is(1,$obj->_percentage_similarity("AAAA","AAAABB"), 'first half the same');
+
+done_testing();
diff --git a/t/Bio/Roary/SplitGroups.t b/t/Bio/Roary/SplitGroups.t
new file mode 100644
index 0000000..796575f
--- /dev/null
+++ b/t/Bio/Roary/SplitGroups.t
@@ -0,0 +1,70 @@
+#!/usr/bin/env perl
+use strict;
+use warnings;
+use Data::Dumper;
+use Test::Files;
+
+BEGIN { unshift( @INC, './lib' ) }
+$ENV{PATH} .= ":./bin";
+
+BEGIN {
+ use Test::Most;
+ use_ok('Bio::Roary::SplitGroups');
+}
+
+my $obj;
+
+# test 1 - 100% shared CGN
+ok( $obj = Bio::Roary::SplitGroups->new(
+ groupfile => 't/data/split_groups/paralog_clusters1',
+ fasta_files => [ 't/data/split_groups/paralogs1.fa', 't/data/split_groups/paralogs2.fa' ],
+ outfile => 'blah.out',
+ _do_sorting => 1
+), 'initalise object');
+
+$obj->split_groups;
+ok( -e 'blah.out', 'output file exists' );
+compare_ok('blah.out','t/data/split_groups/paralog_exp_clusters1', 'split group output correct for test 1');
+
+# test 2 - partial sharing of CGN
+ok( $obj = Bio::Roary::SplitGroups->new(
+ groupfile => 't/data/split_groups/paralog_clusters2',
+ fasta_files => [ 't/data/split_groups/paralogs1.fa', 't/data/split_groups/paralogs2.fa' ],
+ outfile => 'blah2.out',
+ _do_sorting => 1
+), 'initalise object');
+
+$obj->split_groups;
+ok( -e 'blah2.out', 'output file exists' );
+compare_ok('blah2.out', 't/data/split_groups/paralog_exp_clusters2', 'split group output correct for test 2');
+
+# test 3 - one gene with no shared CGN
+ok( $obj = Bio::Roary::SplitGroups->new(
+ groupfile => 't/data/split_groups/paralog_clusters3',
+ fasta_files => [ 't/data/split_groups/paralogs1.fa', 't/data/split_groups/paralogs2.fa' ],
+ outfile => 'blah3.out',
+ _do_sorting => 1
+), 'initalise object');
+
+$obj->split_groups;
+ok( -e 'blah3.out', 'output file exists' );
+compare_ok('blah3.out', 't/data/split_groups/paralog_exp_clusters3', 'split group output correct for test 3');
+
+# test 4 - paralogs inside paralogs (inception paralog)
+ok( $obj = Bio::Roary::SplitGroups->new(
+ groupfile => 't/data/split_groups/paralog_clusters4',
+ fasta_files => [ 't/data/split_groups/paralogs1.fa', 't/data/split_groups/paralogs2.fa', 't/data/split_groups/paralogs3.fa' ],
+ outfile => 'blah4.out',
+ _do_sorting => 1
+), 'initalise object');
+
+$obj->split_groups;
+ok( -e 'blah4.out', 'output file exists' );
+compare_ok('blah4.out','t/data/split_groups/paralog_exp_clusters4', 'split group output correct for test 4');
+
+unlink( "blah.out" );
+unlink( "blah2.out" );
+unlink( "blah3.out" );
+unlink( "blah4.out" );
+
+done_testing();
diff --git a/t/bin/dummy_blastp b/t/bin/dummy_blastp
new file mode 100755
index 0000000..989625b
--- /dev/null
+++ b/t/bin/dummy_blastp
@@ -0,0 +1,16 @@
+#!/usr/bin/env perl
+use Moose;
+use Getopt::Long;
+my ($output_filename,$query,$db,$evalue,$num_threads,$outfmt,$max_target_seqs) ;
+GetOptions(
+ 'query=s' => \$query,
+ 'db=s' => \$db,
+ 'evalue=s' => \$evalue,
+ 'num_threads=s' => \$num_threads,
+ 'outfmt=s' => \$outfmt,
+ 'max_target_seqs=s' => \$max_target_seqs,
+
+);
+system("touch _blast_results");
+
+1;
\ No newline at end of file
diff --git a/t/bin/dummy_cd-hit b/t/bin/dummy_cd-hit
new file mode 100755
index 0000000..c3e21e3
--- /dev/null
+++ b/t/bin/dummy_cd-hit
@@ -0,0 +1,5 @@
+#!/usr/bin/env perl
+system("touch output");
+system("touch output.clstr");
+system("touch output.bak.clstr");
+1;
\ No newline at end of file
diff --git a/t/bin/dummy_makeblastdb b/t/bin/dummy_makeblastdb
new file mode 100755
index 0000000..885b6e4
--- /dev/null
+++ b/t/bin/dummy_makeblastdb
@@ -0,0 +1,18 @@
+#!/usr/bin/env perl
+use Moose;
+use Getopt::Long;
+my($output_filename,$dbtype,$in,$logfile,$parse_seqids,$mask_data);
+GetOptions(
+ 'o|out=s' => \$output_filename,
+ 'd|dbtype=s' => \$dbtype,
+ 'l|logfile=s' => \$logfile,
+ 'i|in=s' => \$in,
+ 'parse_seqids' => \$parse_seqids,
+ 'mask_data=s' => \$mask_data,
+);
+
+system("touch $output_filename.phr");
+system("touch $output_filename.pin");
+system("touch $output_filename.psq");
+
+1;
\ No newline at end of file
diff --git a/t/bin/dummy_mcl b/t/bin/dummy_mcl
new file mode 100755
index 0000000..0f35be9
--- /dev/null
+++ b/t/bin/dummy_mcl
@@ -0,0 +1,12 @@
+#!/usr/bin/env perl
+use Moose;
+use Getopt::Long;
+my ($output_filename,$abc_format,$inflation);
+GetOptions(
+ 'o|output=s' => \$output_filename,
+ 'i|inflation=s' => \$inflation,
+ 'a|abc' => \$abc_format
+);
+
+system("touch $output_filename");
+1;
\ No newline at end of file
diff --git a/t/bin/dummy_mcxdeblast b/t/bin/dummy_mcxdeblast
new file mode 100755
index 0000000..94a7af4
--- /dev/null
+++ b/t/bin/dummy_mcxdeblast
@@ -0,0 +1,2 @@
+#!/usr/bin/env perl
+1;
\ No newline at end of file
diff --git a/t/bin/dummy_segmasker b/t/bin/dummy_segmasker
new file mode 100755
index 0000000..1069b82
--- /dev/null
+++ b/t/bin/dummy_segmasker
@@ -0,0 +1,15 @@
+#!/usr/bin/env perl
+use Moose;
+use Getopt::Long;
+my($output_filename,$dbtype,$in,$logfile,$parse_seqids,$mask_data,$infmt,$outfmt);
+GetOptions(
+ 'o|out=s' => \$output_filename,
+ 'i|in=s' => \$in,
+ 'infmt=s' => \$infmt,
+ 'outfmt=s' => \$outfmt,
+ 'parse_seqids' => \$parse_seqids,
+ 'mask_data=s' => \$mask_data,
+);
+
+system("touch $output_filename");
+1;
\ No newline at end of file
diff --git a/t/data/accessory_graphs/core_deletion b/t/data/accessory_graphs/core_deletion
new file mode 100644
index 0000000..7ff1cab
--- /dev/null
+++ b/t/data/accessory_graphs/core_deletion
@@ -0,0 +1,8 @@
+group_A: 1_AA 2_AA 3_AA
+group_B: 1_BB 2_BB 3_BB
+group_C: 1_CC 2_CC 3_CC
+group_D: 1_DD
+group_E: 1_EE
+group_F: 1_FF
+group_G: 1_GG 2_GG 3_GG
+group_H: 1_HH 2_HH 3_HH
\ No newline at end of file
diff --git a/t/data/accessory_graphs/core_island b/t/data/accessory_graphs/core_island
new file mode 100644
index 0000000..0414a96
--- /dev/null
+++ b/t/data/accessory_graphs/core_island
@@ -0,0 +1,8 @@
+group_A: 1_core_island_A
+group_B: 1_core_island_B
+group_C: 1_core_island_C
+group_D: 1_core_island_D 2_core_island_D 3_core_island_D
+group_E: 1_core_island_E 2_core_island_E 3_core_island_E
+group_F: 1_core_island_F 2_core_island_F 3_core_island_F
+group_G: 1_core_island_G
+group_H: 1_core_island_H
\ No newline at end of file
diff --git a/t/data/accessory_graphs/file_1.fa b/t/data/accessory_graphs/file_1.fa
new file mode 100644
index 0000000..02fa631
--- /dev/null
+++ b/t/data/accessory_graphs/file_1.fa
@@ -0,0 +1,54 @@
+>1_A
+AAAA
+>1_B
+BBBB
+>1_C
+CCCC
+>1_E
+AAAA
+>1_F
+BBBB
+>1_F_insertion
+BBBB
+>1_G
+CCCC
+>1_H
+AAAA
+>1_I
+BBBB
+>1_J
+CCCC
+>1_Z
+DDDD
+>1_AA
+AAAA
+>1_BB
+AAAA
+>1_CC
+AAAA
+>1_DD
+AAAA
+>1_EE
+AAAA
+>1_FF
+AAAA
+>1_GG
+AAAA
+>1_HH
+AAAA
+>1_core_island_A
+AAAA
+>1_core_island_B
+AAAA
+>1_core_island_C
+AAAA
+>1_core_island_D
+AAAA
+>1_core_island_E
+AAAA
+>1_core_island_F
+AAAA
+>1_core_island_G
+AAAA
+>1_core_island_H
+AAAA
\ No newline at end of file
diff --git a/t/data/accessory_graphs/file_1.gff b/t/data/accessory_graphs/file_1.gff
new file mode 100644
index 0000000..cfb2f61
--- /dev/null
+++ b/t/data/accessory_graphs/file_1.gff
@@ -0,0 +1,36 @@
+##gff-version 3
+##sequence-region contig01 1 1500
+contig01 abc CDS 1 90 . - 0 ID=1_A
+contig01 abc CDS 100 190 . + 0 ID=1_B
+contig01 abc CDS 200 290 . + 0 ID=1_C
+contig01 abc CDS 300 390 . - 0 ID=1_E
+contig01 abc CDS 400 490 . + 0 ID=1_F
+contig01 abc CDS 500 590 . + 0 ID=1_F_insertion
+contig01 abc CDS 600 690 . + 0 ID=1_G
+contig01 abc CDS 700 790 . + 0 ID=1_H
+contig02 abc CDS 800 890 . + 0 ID=1_Z
+contig03 abc CDS 1 90 . - 0 ID=1_AA
+contig03 abc CDS 100 190 . + 0 ID=1_BB
+contig03 abc CDS 200 290 . + 0 ID=1_CC
+contig03 abc CDS 300 390 . - 0 ID=1_DD
+contig03 abc CDS 400 490 . + 0 ID=1_EE
+contig03 abc CDS 500 590 . + 0 ID=1_FF
+contig03 abc CDS 600 690 . + 0 ID=1_GG
+contig03 abc CDS 700 790 . + 0 ID=1_HH
+contig04 abc CDS 1 90 . - 0 ID=1_core_island_A
+contig04 abc CDS 100 190 . + 0 ID=1_core_island_B
+contig04 abc CDS 200 290 . + 0 ID=1_core_island_C
+contig04 abc CDS 300 390 . - 0 ID=1_core_island_D
+contig04 abc CDS 400 490 . + 0 ID=1_core_island_E
+contig04 abc CDS 500 590 . + 0 ID=1_core_island_F
+contig04 abc CDS 600 690 . + 0 ID=1_core_island_G
+contig04 abc CDS 700 790 . + 0 ID=1_core_island_H
+##FASTA
+>contig01
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
+>contig02
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
+>contig03
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
+>contig04
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
diff --git a/t/data/accessory_graphs/file_2.fa b/t/data/accessory_graphs/file_2.fa
new file mode 100644
index 0000000..e2a2319
--- /dev/null
+++ b/t/data/accessory_graphs/file_2.fa
@@ -0,0 +1,36 @@
+>2_A
+AAAA
+>2_B
+BBBB
+>2_C
+CCCC
+>2_E
+AAAA
+>2_F
+BBBB
+>2_G
+CCCC
+>2_H
+AAAA
+>2_I
+BBBB
+>2_J
+CCCC
+>2_Z
+DDDD
+>2_AA
+AAAA
+>2_BB
+AAAA
+>2_CC
+AAAA
+>2_GG
+AAAA
+>2_HH
+AAAA
+>2_core_island_D
+AAAA
+>2_core_island_E
+AAAA
+>2_core_island_F
+AAAA
\ No newline at end of file
diff --git a/t/data/accessory_graphs/file_2.gff b/t/data/accessory_graphs/file_2.gff
new file mode 100644
index 0000000..73ecc2f
--- /dev/null
+++ b/t/data/accessory_graphs/file_2.gff
@@ -0,0 +1,27 @@
+##gff-version 3
+##sequence-region contig01 1 1500
+contig01 abc CDS 1 90 . - 0 ID=2_A
+contig01 abc CDS 100 190 . + 0 ID=2_B
+contig01 abc CDS 200 290 . + 0 ID=2_C
+contig01 abc CDS 300 390 . - 0 ID=2_E
+contig01 abc CDS 400 490 . + 0 ID=2_F
+contig01 abc CDS 600 690 . + 0 ID=2_G
+contig01 abc CDS 700 790 . + 0 ID=2_H
+contig02 abc CDS 800 890 . + 0 ID=2_Z
+contig03 abc CDS 1 90 . - 0 ID=2_AA
+contig03 abc CDS 100 190 . + 0 ID=2_BB
+contig03 abc CDS 200 290 . + 0 ID=2_CC
+contig03 abc CDS 600 690 . + 0 ID=2_GG
+contig03 abc CDS 700 790 . + 0 ID=2_HH
+contig04 abc CDS 300 390 . - 0 ID=2_core_island_D
+contig04 abc CDS 400 490 . + 0 ID=2_core_island_E
+contig04 abc CDS 500 590 . + 0 ID=2_core_island_F
+##FASTA
+>contig01
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
+>contig02
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
+>contig03
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
+>contig04
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
diff --git a/t/data/accessory_graphs/file_3.fa b/t/data/accessory_graphs/file_3.fa
new file mode 100644
index 0000000..de397e1
--- /dev/null
+++ b/t/data/accessory_graphs/file_3.fa
@@ -0,0 +1,36 @@
+>3_A
+AAAA
+>3_B
+BBBB
+>3_C
+CCCC
+>3_E
+AAAA
+>3_F
+BBBB
+>3_G
+CCCC
+>3_H
+AAAA
+>3_I
+BBBB
+>3_J
+CCCC
+>3_Z
+DDDD
+>3_AA
+AAAA
+>3_BB
+AAAA
+>3_CC
+AAAA
+>3_GG
+AAAA
+>3_HH
+AAAA
+>3_core_island_D
+AAAA
+>3_core_island_E
+AAAA
+>3_core_island_F
+AAAA
\ No newline at end of file
diff --git a/t/data/accessory_graphs/file_3.gff b/t/data/accessory_graphs/file_3.gff
new file mode 100644
index 0000000..7682649
--- /dev/null
+++ b/t/data/accessory_graphs/file_3.gff
@@ -0,0 +1,27 @@
+##gff-version 3
+##sequence-region contig01 1 1500
+contig01 abc CDS 1 99 . - 0 ID=3_A
+contig01 abc CDS 100 199 . + 0 ID=3_B
+contig01 abc CDS 200 299 . + 0 ID=3_C
+contig01 abc CDS 300 390 . - 0 ID=3_E
+contig01 abc CDS 400 490 . + 0 ID=3_F
+contig01 abc CDS 600 690 . + 0 ID=3_G
+contig01 abc CDS 700 790 . + 0 ID=3_H
+contig02 abc CDS 800 890 . + 0 ID=3_Z
+contig03 abc CDS 1 90 . - 0 ID=3_AA
+contig03 abc CDS 100 190 . + 0 ID=3_BB
+contig03 abc CDS 200 290 . + 0 ID=3_CC
+contig03 abc CDS 600 690 . + 0 ID=3_GG
+contig03 abc CDS 700 790 . + 0 ID=3_HH
+contig04 abc CDS 300 390 . - 0 ID=3_core_island_D
+contig04 abc CDS 400 490 . + 0 ID=3_core_island_E
+contig04 abc CDS 500 590 . + 0 ID=3_core_island_F
+##FASTA
+>contig01
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
+>contig02
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
+>contig03
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
+>contig04
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
\ No newline at end of file
diff --git a/t/data/accessory_graphs/no_accessory b/t/data/accessory_graphs/no_accessory
new file mode 100644
index 0000000..71e8f20
--- /dev/null
+++ b/t/data/accessory_graphs/no_accessory
@@ -0,0 +1,3 @@
+group_A: 1_A 2_A 3_A
+group_B: 1_B 2_B 3_B
+group_C: 1_C 2_C 3_C
\ No newline at end of file
diff --git a/t/data/accessory_graphs/one_branch b/t/data/accessory_graphs/one_branch
new file mode 100644
index 0000000..d9dcdd8
--- /dev/null
+++ b/t/data/accessory_graphs/one_branch
@@ -0,0 +1,5 @@
+group_A: 1_A 2_A 3_A
+group_B1: 1_B
+group_B2: 2_B 3_B
+group_C: 1_C 2_C 3_C
+group_E: 1_E 2_E 3_E
\ No newline at end of file
diff --git a/t/data/accessory_graphs/one_bubble b/t/data/accessory_graphs/one_bubble
new file mode 100644
index 0000000..f6f0271
--- /dev/null
+++ b/t/data/accessory_graphs/one_bubble
@@ -0,0 +1,6 @@
+group_C: 1_C 2_C 3_C
+group_E: 1_E 2_E 3_E
+group_bubble_1: 1_F
+group_bubble_2: 1_F_insertion
+group_F: 2_F 3_F
+group_G: 1_G 2_G 3_G
\ No newline at end of file
diff --git a/t/data/accessory_graphs/single_gene_contig b/t/data/accessory_graphs/single_gene_contig
new file mode 100644
index 0000000..7c1cd4d
--- /dev/null
+++ b/t/data/accessory_graphs/single_gene_contig
@@ -0,0 +1 @@
+group_A: 1_Z 2_Z 3_Z
diff --git a/t/data/accessory_graphs/two_graphs b/t/data/accessory_graphs/two_graphs
new file mode 100644
index 0000000..b6c5aa5
--- /dev/null
+++ b/t/data/accessory_graphs/two_graphs
@@ -0,0 +1,4 @@
+group_A: 1_A 2_A 3_A
+group_B: 1_B 2_B 3_B
+group_G: 1_G 2_G 3_G
+group_H: 1_H 2_H 3_H
\ No newline at end of file
diff --git a/t/data/blast_results b/t/data/blast_results
new file mode 100644
index 0000000..21ebb4e
--- /dev/null
+++ b/t/data/blast_results
@@ -0,0 +1,13 @@
+1234#12_01975 1234#1_01317 100.00 60 0 0 1 60 30 89 8e-38 123
+1234#1_01317 1234#1_01317 100.00 89 0 0 1 89 1 89 1e-60 182
+1234#20_01662 1234#1_01317 100.00 37 0 0 1 37 53 89 3e-20 77.4
+1234#3_01167 1234#1_01317 98.33 60 1 0 1 60 30 89 2e-37 122
+6259_6#6_02209 6259_7#20_00601 99.71 684 2 0 1 684 1427 2110 0.0 1415
+6259_7#20_00601 6259_7#20_00601 100.00 2110 0 0 1 2110 1 2110 0.0 4335
+6593_5#7_01700 6259_7#20_00601 99.72 1057 3 0 1 1057 1054 2110 0.0 2181
+6630_2#15_02136 6259_7#20_00601 100.00 1015 0 0 1 1015 1096 2110 0.0 2104
+6630_4#12_02032 6259_7#20_00601 100.00 1046 0 0 1 1046 1065 2110 0.0 2164
+6631_2#21_02147 6259_7#20_00601 99.13 578 5 0 1 578 1533 2110 0.0 1199
+6631_4#23_02060 6259_7#20_00601 100.00 1290 0 0 1 1290 821 2110 0.0 2663
+6631_7#21_02171 6259_7#20_00601 97.37 684 0 1 1 666 1427 2110 0.0 1371
+6664_1#10_02278 6259_6#6_02209 100.00 404 0 0 1 404 281 684 0.0 838
\ No newline at end of file
diff --git a/t/data/clustered_proteins b/t/data/clustered_proteins
new file mode 100644
index 0000000..7922af2
--- /dev/null
+++ b/t/data/clustered_proteins
@@ -0,0 +1,12 @@
+speH: abc_00004 abc_00004 abc_00004 abc_00006 abc_00006 abc_00006 1_2 2_2 3_2
+group_2: abc_00014 abc_00014 abc_00014 1_6 2_7 abc_00015
+yfnB: abc_00016 abc_00016 3_5
+group_5: abc_00003 abc_00003 abc_00003
+argF: 1_3 2_3 3_3
+group_8: abc_01705 abc_01705 abc_01705
+group_9: abc_00010 abc_00010 abc_00010
+hly: 1_1 2_1 3_1
+arcC1: abc_00008 abc_00008 abc_00008
+group_10: abc_00011 abc_00011 abc_00011
+group_4: abc_00002 abc_00002 abc_00002
+group_11: abc_00012 abc_00012 abc_00012
diff --git a/t/data/clustered_proteins_pan_genome b/t/data/clustered_proteins_pan_genome
new file mode 100644
index 0000000..77d294e
--- /dev/null
+++ b/t/data/clustered_proteins_pan_genome
@@ -0,0 +1,21 @@
+group_13: abc_00014 abc_00014
+speH: 1_2 2_2
+arcC1: abc_00008 abc_00008
+group_2: abc_00002 abc_00002
+yfnB: abc_00016 abc_00016
+group_10: abc_00010 abc_00010
+group_12: abc_00012 abc_00012
+hly: 1_1 2_1
+group_6: abc_00006 abc_00006
+group_9: abc_01705 abc_01705
+group_14: 1_6 2_7
+group_3: abc_00003 abc_00003
+argF: 1_3 2_3
+group_11: abc_00011 abc_00011
+group_4: abc_00004 abc_00004
+group_18: abc_50010
+group_20: abc_50014
+group_16: abc_50002
+group_17: 3_3
+group_21: 3_5
+group_19: abc_50012
diff --git a/t/data/clustered_proteins_post_analysis b/t/data/clustered_proteins_post_analysis
new file mode 100644
index 0000000..8688f1e
--- /dev/null
+++ b/t/data/clustered_proteins_post_analysis
@@ -0,0 +1,13 @@
+group_12: abc_00002 abc_00002
+group_13: abc_00003 abc_00003
+group_5: 1_6 2_7
+hly: 1_1 2_1
+group_6: abc_01705 abc_01705
+group_8: abc_00011 abc_00011
+speH: 1_2 2_2
+group_2: abc_00004 abc_00004
+group_3: abc_00006 abc_00006
+group_7: abc_00010 abc_00010
+yfnB: abc_00016 abc_00016
+arcC1: abc_00008 abc_00008
+argF: 1_3 2_3
diff --git a/t/data/clusters_input.fa b/t/data/clusters_input.fa
new file mode 100644
index 0000000..9e028da
--- /dev/null
+++ b/t/data/clusters_input.fa
@@ -0,0 +1,20 @@
+>2363_5_03666
+AAAAAAAAAAAAAGGGGGGGGGGGGGG
+>4075_2#3_03437
+AAAAAAAAAAAAAGGGGGGGGGGGGGG
+>4075_1#8_03461
+AAAAAAAAAAAAAGGGGGGGGGGGGGG
+>2212_3_02841
+AAAAAAAAAAAAAGGGGGGGGGGGGGG
+>2363_5_00947
+AAAAAAAAAAAAAGGGGGGGGGGGGGG
+>2363_7_00085
+AAAAAAAAAAAAAGGGGGGGGGGGGGG
+>2460_2_00826
+AAAAAAAAAAAAAGGGGGGGGGGGGGG
+>4075_1#6_04091
+AAAAAAAAAAAAAGGGGGGGGGGGGGG
+>4075_1#3_04238
+AAAAAAAAAAAAAGGGGGGGGGGGGGG
+>3634_6_04078
+AAAAAAAAAAAAAGGGGGGGGGGGGGG
diff --git a/t/data/clusters_to_inflate b/t/data/clusters_to_inflate
new file mode 100644
index 0000000..e4ec02b
--- /dev/null
+++ b/t/data/clusters_to_inflate
@@ -0,0 +1,40 @@
+>Cluster 43
+0 2184aa, >2363_5_03666... *
+>Cluster 44
+0 2138aa, >4075_2#3_03437... *
+>Cluster 45
+0 2130aa, >2212_1_02994... at 99.48%
+1 2130aa, >2212_6_02081... at 99.01%
+2 2130aa, >2363_1_00606... at 99.48%
+3 2130aa, >2363_2_02124... at 99.48%
+4 2130aa, >2363_3_01371... at 99.39%
+5 2130aa, >2363_6_01272... at 99.15%
+6 2130aa, >2363_8_00966... at 99.48%
+7 2130aa, >2541_2_02425... at 99.48%
+8 2130aa, >2541_3_02449... at 99.01%
+9 2130aa, >2541_7_00441... at 99.48%
+10 2130aa, >2541_8_00644... at 99.48%
+11 2130aa, >2781_2_02909... at 99.48%
+12 2130aa, >3634_6_00968... at 99.48%
+13 2130aa, >3634_7_01056... at 99.39%
+14 2130aa, >3634_8_02606... at 99.48%
+15 2137aa, >4075_1#8_03461... *
+>Cluster 46
+0 2132aa, >2212_3_02841... *
+>Cluster 47
+0 2130aa, >2363_5_00947... *
+>Cluster 48
+0 2130aa, >2363_7_00085... *
+>Cluster 49
+0 2130aa, >2460_2_00826... *
+>Cluster 50
+0 2054aa, >4075_1#6_04091... *
+>Cluster 51
+0 2042aa, >4075_1#3_04238... *
+>Cluster 52
+0 1994aa, >2212_1_01414... at 99.75%
+1 1994aa, >2363_1_00811... at 99.95%
+2 1994aa, >2541_2_00696... at 99.95%
+3 1994aa, >2541_8_00920... at 99.95%
+4 2005aa, >3634_6_04078... *
+5 2005aa, >3634_7_00911... at 99.95%
\ No newline at end of file
diff --git a/t/data/clusters_to_inflate.mcl b/t/data/clusters_to_inflate.mcl
new file mode 100644
index 0000000..97f4006
--- /dev/null
+++ b/t/data/clusters_to_inflate.mcl
@@ -0,0 +1,4 @@
+2363_5_03666 4075_2#3_03437
+4075_1#8_03461
+2212_3_02841 2363_5_00947
+2363_7_00085 2460_2_00826 4075_1#6_04091 4075_1#3_04238 3634_6_04078
\ No newline at end of file
diff --git a/t/data/clusters_to_inflate_original_input.fa b/t/data/clusters_to_inflate_original_input.fa
new file mode 100644
index 0000000..ef3f0b4
--- /dev/null
+++ b/t/data/clusters_to_inflate_original_input.fa
@@ -0,0 +1,60 @@
+>2212_1_01414
+AAAGGGTTT
+>4075_1#3_04238
+AAAGGGTTT
+>4075_1#6_04091
+AAAGGGTTT
+>2212_1_02994
+AAAGGGTTT
+>2363_5_00947
+AAAGGGTTT
+>2363_7_00085
+AAAGGGTTT
+>2460_2_00826
+AAAGGGTTT
+>2212_3_02841
+AAAGGGTTT
+>4075_2#3_03437
+AAAGGGTTT
+>2363_5_03666
+AAAGGGTTT
+>2363_1_00811
+AAAGGGTTT
+>2212_6_02081
+AAAGGGTTT
+>2541_8_00644
+AAAGGGTTT
+>2781_2_02909
+AAAGGGTTT
+>3634_6_00968
+AAAGGGTTT
+>3634_7_01056
+AAAGGGTTT
+>3634_8_02606
+AAAGGGTTT
+>4075_1#8_03461
+AAAGGGTTT
+>2541_2_00696
+AAAGGGTTT
+>2363_1_00606
+AAAGGGTTT
+>2541_8_00920
+AAAGGGTTT
+>2363_2_02124
+AAAGGGTTT
+>3634_6_04078
+AAAGGGTTT
+>2363_3_01371
+AAAGGGTTT
+>3634_7_00911
+AAAGGGTTT
+>2363_6_01272
+AAAGGGTTT
+>2363_8_00966
+AAAGGGTTT
+>2541_2_02425
+AAAGGGTTT
+>2541_3_02449
+AAAGGGTTT
+>2541_7_00441
+AAAGGGTTT
diff --git a/t/data/clustersfile b/t/data/clustersfile
new file mode 100644
index 0000000..42b2d7f
--- /dev/null
+++ b/t/data/clustersfile
@@ -0,0 +1,33 @@
+>Cluster 1
+0 4863aa, >6259_8#9_01142... *
+>Cluster 2
+0 4666aa, >6631_2#11_00851... *
+>Cluster 3
+0 4516aa, >6631_4#5_01901... *
+>Cluster 4
+0 4230aa, >6664_1#21_00211... *
+>Cluster 5
+0 4220aa, >6259_8#13_01077... *
+>Cluster 6
+0 4201aa, >6630_4#9_00008... *
+1 4201aa, >6631_1#23_00379... at 100.00%
+2 4201aa, >6631_2#7_00715... at 99.95%
+3 4201aa, >6631_5#1_00087... at 99.95%
+4 4201aa, >6649_8#10_00838... at 99.95%
+5 4201aa, >6664_1#13_00087... at 99.95%
+>Cluster 7
+0 4195aa, >6259_5#1_00688... *
+>Cluster 8
+0 4165aa, >6259_5#8_00815... *
+>Cluster 9
+0 4153aa, >6259_7#7_02078... *
+1 4153aa, >6259_7#8_01884... at 100.00%
+2 4153aa, >6631_2#22_01965... at 99.95%
+>Cluster 10
+0 4153aa, >6631_5#24_01032... *
+>Cluster 11
+0 4124aa, >6593_5#13_00457... *
+1 4124aa, >6630_1#9_00031... at 100.00%
+2 4124aa, >6630_3#1_00008... at 100.00%
+3 4124aa, >6630_3#2_00088... at 100.00%
+4 4124aa, >6631_1#4_00087... at 100.00%
\ No newline at end of file
diff --git a/t/data/core_alignment.csv b/t/data/core_alignment.csv
new file mode 100644
index 0000000..0c0703a
--- /dev/null
+++ b/t/data/core_alignment.csv
@@ -0,0 +1,4 @@
+"Gene","Non-unique Gene name","Annotation","No. isolates","No. sequences","Avg sequences per isolate","Genome Fragment","Order within Fragment","Accessory Fragment","Accessory Order with Fragment","QC","Min group size nuc","Max group size nuc","Avg group size nuc","query_1","query_2"
+"hly","","Alpha-toxin","2","2","1","1","7",,,"",,,,"query_1_1","query_2_1"
+"speH","","hypothetical protein","2","2","1","1","11",,,"",,,,"query_1_2","query_2_2"
+"argF","","Ornithine carbamoyltransferase","2","2","1","1","6",,,"",,,,"query_1_3","query_2_3"
diff --git a/t/data/core_alignment/argF.fa.aln b/t/data/core_alignment/argF.fa.aln
new file mode 100644
index 0000000..92d144b
--- /dev/null
+++ b/t/data/core_alignment/argF.fa.aln
@@ -0,0 +1,4 @@
+>query_1_3
+AAAAA-
+>query_2_3
+CCCCC-
\ No newline at end of file
diff --git a/t/data/core_alignment/hly.fa.aln b/t/data/core_alignment/hly.fa.aln
new file mode 100644
index 0000000..e5c0a1e
--- /dev/null
+++ b/t/data/core_alignment/hly.fa.aln
@@ -0,0 +1,4 @@
+>query_1_1
+GGGGG
+>query_2_1
+TTTTT
\ No newline at end of file
diff --git a/t/data/core_alignment/speH.fa.aln b/t/data/core_alignment/speH.fa.aln
new file mode 100644
index 0000000..954f5d4
--- /dev/null
+++ b/t/data/core_alignment/speH.fa.aln
@@ -0,0 +1,4 @@
+>query_1_2
+TTTTT
+>query_2_2
+GGGGG
\ No newline at end of file
diff --git a/t/data/core_alignment_core0.66.csv b/t/data/core_alignment_core0.66.csv
new file mode 100644
index 0000000..8bbe319
--- /dev/null
+++ b/t/data/core_alignment_core0.66.csv
@@ -0,0 +1,4 @@
+"Gene","Non-unique Gene name","Annotation","No. isolates","No. sequences","Avg sequences per isolate","Genome Fragment","Order within Fragment","Accessory Fragment","Accessory Order with Fragment","QC","Min group size nuc","Max group size nuc","Avg group size nuc","query_1","query_2","query_3"
+"hly","","Alpha-toxin","1","1","1","1","7",,,"",,,,"query_1_1","",""
+"speH","","hypothetical protein","2","2","1","1","11",,,"",,,,"query_1_2","query_2_2",""
+"argF","","Ornithine carbamoyltransferase","1","1","1","1","6",,,"",,,,"","query_2_3",""
diff --git a/t/data/core_alignment_gene_lookup/expected_core_gene_alignment.aln b/t/data/core_alignment_gene_lookup/expected_core_gene_alignment.aln
new file mode 100644
index 0000000..227cd1c
--- /dev/null
+++ b/t/data/core_alignment_gene_lookup/expected_core_gene_alignment.aln
@@ -0,0 +1,45 @@
+>query_1
+ATGAATCTACCTTTACCTGATAATTATGAATTTGTGTTTTTATCTGGTGGATTATCTGGG
+CATGCTGCAATGATGTCATTTTTTAATGTTTGTGGCATTGGATATTTGTATCATCATATG
+GATTTAATGAAAAATAGATATATAGATTATTACCATTTTTCTAGGATTGAAAATTTATAT
+TCAATTATAACATATGGACAATACAGTTTAACGCAAGGAATGAATAATATAGGTAAATAT
+TTGACTTTAATTAATAAAATTCCAATTCTTTTTTTGGTAAGAGATCCCATATCAAGACTA
+AAAACCGGAGTAAATCATCCTATTCTAAATCCAAAAAGTATGAAGGAGATATGTTTAAAC
+AATGATTATAGTGATGTGTTTAAGAATAAAATGTATGTTGGCGATATTGGAAAAAATTTT
+TACTATTCAGAAAAGCCAAGCATGAAATATTTACCTAGATTGAAATATGAAAATTTGGGA
+ATATTTTTAAAACCACAAGAATTTGAGCGTTTAAAGCAAGATTCTAAGCTATTTGATGTT
+GCTAAAAGATATTTGAATAATTTTATTGAAGCTTTAGAAGAGAGAATAGACCTAGAAAAA
+GCTAAATTATTTAAAGAAAAAGACGTGTTAAACTATTTAAAAGAAAATAAAGAATTAAGA
+GTTAAGTTAAAAAACATATTAGATAAAGAACTTGTTCATATTAAACAACATCGTCCAGAT
+ATAGTAGCTTCTTGGAAATACTATCAAGAATTTGAACAAATGTGCAAGGAGTTGAATGGT
+AATATTTAG
+>query_2
+ATGAATCTACCTTTACCTGATAATTATGAATTTGTGTTTTTATCTGGTGGATTATCTGGG
+CATGCTGCAATGATGTCATTTTTTAATGTTTGTGGCATTGGATATTTGTATCATCATATG
+GATTTAATGAAAAATAGATATATAGATTATTACCATTTTTCTAGGATTGAAAATTTATAT
+TCAATTATAACATATGGACAATACAGTTTAACGCAAGGAATGAATAATATAGGTAAATAT
+TTGACTTTAATTAATNNNNNNNNNATTCTTTTTTTGGTAAGAGATCCCATATCAAGACTA
+AAAACCGGAGTAAATCATCCTATTCTAAATCCAAAAAGTATGAAGGAGATATGTTTAAAC
+AATGATTATAGTGATNNNNNNNNNAATAAAATGTATGTTGGCGATATTGGAAAAAATTTT
+TACTATTCAGAAAAGCCAAGCATGAAATATTTACCTAGATTGAAATATGAAAATTTGGGA
+ATATTTTTAAAACCACAAGAATTTGAGCGTTTAAAGCAAGATTCTAAGCTATTTGATGTT
+GCTAAAAGATATTTGAATAATTTTATTGAAGCTTTAGAAGAGAGAATAGACCTAGAAAAA
+GCTAAATTATTTAAAGAAAAAGACGTGTTAAACTATTTAAAAGAAAATAAAGAATTAAGA
+GTTAAGTTAAAAAACATATTAGATAAAGAACTTGTTCATATTAAACAACATCGTCCAGAT
+ATAGTAGCTTCTTGGAAATACTATCAAGAATTTGAACAAATGTGCAAGGAGTTGAATGGT
+AATATTTAG
+>query_3
+ATGAATCTACCTTTACCTGATAATTATGAATTTGTGTTTTTATCTGGTGGATTATCTGGG
+CATGCTGCAATGATGTCATTTTTTAATGTTTGTGGCATTGGATATTTGTATCATCATATG
+GATTTAATGAAAAATAGATATATAGATTATTACCATTTTTCTAGGATTGAAAATTTATAT
+TCAATTATAACATATGGACAATACAGTTTAACGCAAGGAATGAATAATATAGGTAAATAT
+TTGACTTTAATTAATAAAATTCCAATTCTTTTTTTGGTAAGAGATCCCATATCAAGACTA
+AAAACCGGAGTAAATCATCCTATTCTAAATCCAAAAAGTATGAAGGAGATATGTTTAAAC
+AATGATTATAGTGATGTGTTTAAGAATAAAATGTATGTTGGCGATATTGGAAAAAATTTT
+TACTATTCAGAAAAGCCAAGCATGAAATATTTACCTAGATTGAAATATGAAAATTTGGGA
+ATATTTTTAAAACCACAAGAATTCGAGCGTTTAAAGCAAGATTCTAAGCTATTTGATGTT
+GCTAAAAGATATTTGAATAATTTTATTGAAGCTTTAGAAGAGAGAATAGACCTAGAAAAA
+GCTAAATTATTTAAAGAAAAAGACGTGTTAAACTATTTAAAAGAAAATAAAGAATTAAGA
+GTTAAGTTAAAAAACATATTAGATAAAGAACTTGTTCATATTAAACAACATCGTCCAGAT
+ATAGTAGCTTCTTGGAAATACTATCAAGAATTTGAACAAATGTGCAAGGAGTTGAATGGT
+AATATTTAG
diff --git a/t/data/core_alignment_gene_lookup/query_1.gff b/t/data/core_alignment_gene_lookup/query_1.gff
new file mode 100644
index 0000000..a3dc10a
--- /dev/null
+++ b/t/data/core_alignment_gene_lookup/query_1.gff
@@ -0,0 +1,29 @@
+##gff-version 3
+##sequence-region gnl|IFR|Ef_ABC123_contig000001 1 1320
+gnl|IFR|Ef_ABC123_contig000001 Prodigal:2.6 CDS 52 513 . + 0 ID=Ef_ABC123_00010;Parent=Ef_ABC123_00010_gene;inference=ab initio prediction:Prodigal:2.6,similar to AA sequence:RefSeq:CJSA_1363;locus_tag=Ef_ABC123_00010;product=CJSA_1363 putative sugar transferase:1372570 reverse MW:76273;protein_id=gnl|IFR|Ef_ABC123_00010
+gnl|IFR|Ef_ABC123_contig000001 Prodigal:2.6 CDS 510 746 . + 0 ID=Ef_ABC123_00020;Parent=Ef_ABC123_00020_gene;inference=ab initio prediction:Prodigal:2.6,similar to AA sequence:RefSeq:CJSA_1363;locus_tag=Ef_ABC123_00020;product=CJSA_1363 putative sugar transferase:1372570 reverse MW:76273;protein_id=gnl|IFR|Ef_ABC123_00020
+gnl|IFR|Ef_ABC123_contig000001 Prodigal:2.6 CDS 878 1207 . + 0 ID=Ef_ABC123_00030;Parent=Ef_ABC123_00030_gene;inference=ab initio prediction:Prodigal:2.6,similar to AA sequence:RefSeq:A911_06907;locus_tag=Ef_ABC123_00030;product=A911_06907 putative sugar transferase:1355468 reverse MW:73559;protein_id=gnl|IFR|Ef_ABC123_00030
+##FASTA
+>gnl|IFR|Ef_ABC123_contig000001
+GAAAAAGAAAAAATAAACTATAAAAACATATCAGCTGAACTTGCTTGGGAAATGAATCTA
+CCTTTACCTGATAATTATGAATTTGTGTTTTTATCTGGTGGATTATCTGGGCATGCTGCA
+ATGATGTCATTTTTTAATGTTTGTGGCATTGGATATTTGTATCATCATATGGATTTAATG
+AAAAATAGATATATAGATTATTACCATTTTTCTAGGATTGAAAATTTATATTCAATTATA
+ACATATGGACAATACAGTTTAACGCAAGGAATGAATAATATAGGTAAATATTTGACTTTA
+ATTAATAAAATTCCAATTCTTTTTTTGGTAAGAGATCCCATATCAAGACTAAAAACCGGA
+GTAAATCATCCTATTCTAAATCCAAAAAGTATGAAGGAGATATGTTTAAACAATGATTAT
+AGTGATGTGTTTAAGAATAAAATGTATGTTGGCGATATTGGAAAAAATTTTTACTATTCA
+GAAAAGCCAAGCATGAAATATTTACCTAGATGATTAATGAAGATACAATGTATCAGACAT
+CGCTTTGCTTATTATTTTCAAATAGAGATATTACTTATATTGACATGGAAGAAATAAAAC
+CAGCAAAGGCATTCGATACAATGTGTGATTTAGCTAACAAATTTGGTTTTAAGAAACCAA
+CGGATAAAAAATTTTTTGAAGGAGTTATGAATGGAGATTTAGCAGGTTTTATACCTATTA
+ATTTATTTATTGATAAAAAAATTTAATTTATAATAACAAAGTTATTTATAAAGATAATGA
+TAGCATCCATCTTCAAATCACATCTACAAATTTAATTGAAATTTATAAACAATCTAAAGA
+ATATATCAACTTTACTAAAGAATTTTTTGATAAACCTTTGAAATATGAAAATTTGGGAAT
+ATTTTTAAAACCACAAGAATTTGAGCGTTTAAAGCAAGATTCTAAGCTATTTGATGTTGC
+TAAAAGATATTTGAATAATTTTATTGAAGCTTTAGAAGAGAGAATAGACCTAGAAAAAGC
+TAAATTATTTAAAGAAAAAGACGTGTTAAACTATTTAAAAGAAAATAAAGAATTAAGAGT
+TAAGTTAAAAAACATATTAGATAAAGAACTTGTTCATATTAAACAACATCGTCCAGATAT
+AGTAGCTTCTTGGAAATACTATCAAGAATTTGAACAAATGTGCAAGGAGTTGAATGGTAA
+TATTTAGGAGAAAGATTTGTAAATTAATAAAAAAAAGATATAATTGTGTTTAAAATTAGA
+GAAAGGAATCAATATGAAACAAGGGGATTTTACAAAAGTTGCAAAACATTATCACAATAG
\ No newline at end of file
diff --git a/t/data/core_alignment_gene_lookup/query_2.gff b/t/data/core_alignment_gene_lookup/query_2.gff
new file mode 100644
index 0000000..2638a86
--- /dev/null
+++ b/t/data/core_alignment_gene_lookup/query_2.gff
@@ -0,0 +1,29 @@
+##gff-version 3
+##sequence-region gnl|IFR|Ef_EFG123_contig000001 1 1320
+gnl|IFR|Ef_EFG123_contig000001 Prodigal:2.6 CDS 52 513 . + 0 ID=Ef_EFG123_00010;Parent=Ef_EFG123_00010_gene;inference=ab initio prediction:Prodigal:2.6,similar to AA sequence:RefSeq:CJSA_1363;locus_tag=Ef_EFG123_00010;product=CJSA_1363 putative sugar transferase:1372570 reverse MW:76273;protein_id=gnl|IFR|Ef_EFG123_00010
+gnl|IFR|Ef_EFG123_contig000001 Prodigal:2.6 CDS 510 746 . + 0 ID=Ef_EFG123_00020;Parent=Ef_EFG123_00020_gene;inference=ab initio prediction:Prodigal:2.6,similar to AA sequence:RefSeq:CJSA_1363;locus_tag=Ef_EFG123_00020;product=CJSA_1363 putative sugar transferase:1372570 reverse MW:76273;protein_id=gnl|IFR|Ef_EFG123_00020
+gnl|IFR|Ef_EFG123_contig000001 Prodigal:2.6 CDS 878 1207 . + 0 ID=Ef_EFG123_00030;Parent=Ef_EFG123_00030_gene;inference=ab initio prediction:Prodigal:2.6,similar to AA sequence:RefSeq:A911_06907;locus_tag=Ef_EFG123_00030;product=A911_06907 putative sugar transferase:1355468 reverse MW:73559;protein_id=gnl|IFR|Ef_EFG123_00030
+##FASTA
+>gnl|IFR|Ef_EFG123_contig000001
+GAAAAAGAAAAAATAAACTATAAAAACATATCAGCTGAACTTGCTTGGGAAATGAATCTA
+CCTTTACCTGATAATTATGAATTTGTGTTTTTATCTGGTGGATTATCTGGGCATGCTGCA
+ATGATGTCATTTTTTAATGTTTGTGGCATTGGATATTTGTATCATCATATGGATTTAATG
+AAAAATAGATATATAGATTATTACCATTTTTCTAGGATTGAAAATTTATATTCAATTATA
+ACATATGGACAATACAGTTTAACGCAAGGAATGAATAATATAGGTAAATATTTGACTTTA
+ATTAATAANNNNNNNATTCTTTTTTTGGTAAGAGATCCCATATCAAGACTAAAAACCGGA
+GTAAATCATCCTATTCTAAATCCAAAAAGTATGAAGGAGATATGTTTAAACAATGATTAT
+AGTGATGTNNNNNNNAATAAAATGTATGTTGGCGATATTGGAAAAAATTTTTACTATTCA
+GAAAAGCCAAGCATGAAATATTTACCTAGATGATTAATGAAGATACAATGTATCAGACAT
+CGCTTTGCNNNNNNTTTTCAAATAGAGATATTACTTATATTGACATGGAAGAAATAAAAC
+CAGCAAAGGCATTCGATACAATGTGTGATTTAGCTAACAAATTTGGTTTTAAGAAACCAA
+CGGATAAAAAATTTTTTGAAGGAGTTATGAATGGAGATTTAGCAGGTTTTATACCTATTA
+ATTTATTTNNNNNNNAAAAAATTTAATTTATAATAACAAAGTTATTTATAAAGATAATGA
+TAGCATCCATCTTCAAATCACATCTACAAATTTAATTGAAATTTATAAACAATCTAAAGA
+ATATATCAACTTTACTAAAGAATTTTTTGATAAACCTTTGAAATATGAAAATTTGGGAAT
+ATTTTTAAAACCACAAGAATTTGAGCGTTTAAAGCAAGATTCTAAGCTATTTGATGTTGC
+TAAAAGATATTTGAATAATTTTATTGAAGCTTTAGAAGAGAGAATAGACCTAGAAAAAGC
+TAAATTATTTAAAGAAAAAGACGTGTTAAACTATTTAAAAGAAAATAAAGAATTAAGAGT
+TAAGTTAAAAAACATATTAGATAAAGAACTTGTTCATATTAAACAACATCGTCCAGATAT
+AGTAGCTTCTTGGAAATACTATCAAGAATTTGAACAAATGTGCAAGGAGTTGAATGGTAA
+TATTTAGGAGAAAGATTTGTAAATTAATAAAAAAAAGATATAATTGTGTTTAAAATTAGA
+GAAAGGAATCAATATGAAACAAGGGGATTTTACAAAAGTTGCAAAACATTATCACAATAG
\ No newline at end of file
diff --git a/t/data/core_alignment_gene_lookup/query_3.gff b/t/data/core_alignment_gene_lookup/query_3.gff
new file mode 100644
index 0000000..2813d43
--- /dev/null
+++ b/t/data/core_alignment_gene_lookup/query_3.gff
@@ -0,0 +1,29 @@
+##gff-version 3
+##sequence-region gnl|IFR|Ef_HIJ123_contig000001 1 1320
+gnl|IFR|Ef_HIJ123_contig000001 Prodigal:2.6 CDS 52 513 . + 0 ID=Ef_HIJ123_00010;Parent=Ef_HIJ123_00010_gene;inference=ab initio prediction:Prodigal:2.6,similar to AA sequence:RefSeq:CJSA_1363;locus_tag=Ef_HIJ123_00010;product=CJSA_1363 putative sugar transferase:1372570 reverse MW:76273;protein_id=gnl|IFR|Ef_HIJ123_00010
+gnl|IFR|Ef_HIJ123_contig000001 Prodigal:2.6 CDS 510 746 . + 0 ID=Ef_HIJ123_00020;Parent=Ef_HIJ123_00020_gene;inference=ab initio prediction:Prodigal:2.6,similar to AA sequence:RefSeq:CJSA_1363;locus_tag=Ef_HIJ123_00020;product=CJSA_1363 putative sugar transferase:1372570 reverse MW:76273;protein_id=gnl|IFR|Ef_HIJ123_00020
+gnl|IFR|Ef_HIJ123_contig000001 Prodigal:2.6 CDS 878 1207 . + 0 ID=Ef_HIJ123_00030;Parent=Ef_HIJ123_00030_gene;inference=ab initio prediction:Prodigal:2.6,similar to AA sequence:RefSeq:A911_06907;locus_tag=Ef_HIJ123_00030;product=A911_06907 putative sugar transferase:1355468 reverse MW:73559;protein_id=gnl|IFR|Ef_HIJ123_00030
+##FASTA
+>gnl|IFR|Ef_HIJ123_contig000001
+GAAAAAGAAAAAATAAACTATAAAAACATATCAGCTGAACTTGCTTGGGAAATGAATCTA
+CCTTTACCTGATAATTATGAATTTGTGTTTTTATCTGGTGGATTATCTGGGCATGCTGCA
+ATGATGTCATTTTTTAATGTTTGTGGCATTGGATATTTGTATCATCATATGGATTTAATG
+AAAAATAGATATATAGATTATTACCATTTTTCTAGGATTGAAAATTTATATTCAATTATA
+ACATATGGACAATACAGTTTAACGCAAGGAATGAATAATATAGGTAAATATTTGACTTTA
+ATTAATAAAATTCCAATTCTTTTTTTGGTAAGAGATCCCATATCAAGACTAAAAACCGGA
+GTAAATCATCCTATTCTAAATCCAAAAAGTATGAAGGAGATATGTTTAAACAATGATTAT
+AGTGATGTGTTTAAGAATAAAATGTATGTTGGCGATATTGGAAAAAATTTTTACTATTCA
+GAAAAGCCAAGCATGAAATATTTACCTAGATGATTAATGAAGATACAATGTATCAGACAT
+CGCTTTGCTTATTATTTTCAAATAGAGATATTACTTATATTGACATGGAAGAAATAAAAC
+CAGCAAAGGCATTCGATACAATGTGTGATTCAGCTAACAAATTTGGTTTTAAGAAACCAA
+CGGATAAAAAATTTTTTGAAGGAGTTATGAATGGAGATTTAGCAGGTTTTATACCTATTA
+ATTTATTTATTGATAAAAAAATTTAATTTATAATAACAAAGTTATTTATAAAGATAATGA
+TAGCATCCATCTTCAAATCACATCTACAAATTTAATTGAAATTTATAAACAATCTAAAGA
+ATATATCAACTTTACTAAAGAATTTTTTGATAAACCTTTGAAATATGAAAATTTGGGAAT
+ATTTTTAAAACCACAAGAATTCGAGCGTTTAAAGCAAGATTCTAAGCTATTTGATGTTGC
+TAAAAGATATTTGAATAATTTTATTGAAGCTTTAGAAGAGAGAATAGACCTAGAAAAAGC
+TAAATTATTTAAAGAAAAAGACGTGTTAAACTATTTAAAAGAAAATAAAGAATTAAGAGT
+TAAGTTAAAAAACATATTAGATAAAGAACTTGTTCATATTAAACAACATCGTCCAGATAT
+AGTAGCTTCTTGGAAATACTATCAAGAATTTGAACAAATGTGCAAGGAGTTGAATGGTAA
+TATTTAGGAGAAAGATCTGTAAATTAATAAAAAAAAGATATAACTGTGTTTAAAATTAGA
+GAAAGGAATCAATATGAAACAAGGGGATTTTACAAAAGTTGCAAAACATTATCACAATAG
\ No newline at end of file
diff --git a/t/data/core_group_statistics.csv b/t/data/core_group_statistics.csv
new file mode 100644
index 0000000..842ed55
--- /dev/null
+++ b/t/data/core_group_statistics.csv
@@ -0,0 +1,11 @@
+"Gene","Non-unique Gene name","Annotation","No. isolates","No. sequences","Avg sequences per isolate","Genome Fragment","Order within Fragment","Accessory Fragment","Accessory Order with Fragment","QC","Min group size nuc","Max group size nuc","Avg group size nuc","query_1","query_2"
+"group_5","","Gonococcal growth inhibitor III","2","2","1","3","2",,,"",,,,"1_6","2_7"
+"hly","","Alpha-toxin","2","2","1.01","1","7",,,"",,,,"1_1","2_1"
+"speH","","hypothetical protein","2","2","1","1","11",,,"",,,,"1_2","2_2"
+"argF","","Ornithine carbamoyltransferase","2","2","1","1","6",,,"",,,,"1_3","2_3"
+"group_12","","hypothetical protein","1","2","2","2","8",,,"",,,,"","abc_00002 abc_00002"
+"group_13","","hypothetical protein","1","2","2","1","9",,,"",,,,"","abc_00003 abc_00003"
+"group_6","","","1","2","1.99","","","","","",,,,"","abc_01705 abc_01705"
+"group_8","","C4-dicarboxylate transporter/malic acid transport protein","1","2","2","1","3",,,"",,,,"","abc_00011 abc_00011"
+"group_2","","superantigen-like protein","1","2","2","1","10",,,"",,,,"","abc_00004 abc_00004"
+"arcC1","","Carbamate kinase 1","2","2","0.99","1","5",,,"",,,,"","abc_00008 abc_00008"
diff --git a/t/data/empty_file b/t/data/empty_file
new file mode 100644
index 0000000..e69de29
diff --git a/t/data/example_1.faa b/t/data/example_1.faa
new file mode 100644
index 0000000..d0f6304
--- /dev/null
+++ b/t/data/example_1.faa
@@ -0,0 +1,29 @@
+>1234#10_00001 nudix hydrolase
+MSKHGFFQITQKLFLRKGDELLILRDRKSGLGDLPGGRMNENEFFEDWSLSMQREIEEEL
+GSQVQIRVSTKPLFIHKHKVNEGNFPCIIIAYHADYLGGDIILSDEHDYISWEKVQTYEP
+SPLFTEYMLDAVNLYLKEYAPLVH*
+>1234#10_00002 intramembrane serine protease
+MIIKLKIILNSYLIYYFLRGQNTLIRTLLFEFPLTTFFVFLMVATFFIVNVFLPEHLIRQ
+YFLNHPGQIQPLSWIGAVFYHGNLIHLFGNMFYLFFLGRAVEYKAGKGRWLLFFFMAALI
+SSLLDSFIRGVILHDPTPVVGASGAISGIAAVAALLSPFSLRFNQRNIPFPVFLVAWIMV
+YSDITNVFTEDGVARWAHLGGFISVIFAAYFLKPTERKQLHSGFILNLIFIILTLILAFF
+YSNRS*
+>1234#10_00003 hypothetical protein
+VKTTLSGEIEKLRYEVAVKIVNLQGEVLDLRAEMKINFSEVNSKILKLQFEFEMAKIRKE
+LKTEIADLRAETKTDFLELQKSIVDIYKTISTQTRWILGVATLFAAIGKVIN*
+>1234#10_00005 imidazoleglycerol-phosphate dehydratase or histidinol-phosphatase
+LTDKLIGFYDPVRMKAERKTSETEIKLEMNLRGTGQYQFDTEIPFFEHMLSHISKHGLID
+LNLWLRGDIEIDCHHSVEDTAILMGATIHKQLGDKAGIFRYGHFTLTMDEVLTTVAVDLG
+GRYFFKYTGPELTGKFGIYDAELSLEFLQKLALNAKMNLHVVVHYGDNKHHVHESIFKAL
+GKALRMAIAQDSAAAGAIPSTKGVLE*
+>1234#10_00006 imidazole glycerol phosphate synthase subunit HisH
+MIAILDYGMGNIHSCLKAVSLYTKDFVFTKDHSTIENSKALILPGDGHFDKAMENLNSTG
+LRKTIDKHVTSGKPLFGICIGFQILFESSEEIAQGSKKEQIEGLGYIKGKIKKFHGKDFK
+VPHIGWNRLQIRRKDKSVLLKGIGDQSFFYFIHSYRPTDAEGNAITGLCDYYQEKFPAVV
+EKNNIFGTQFHPEKSHTHGLKLLENFIRFI*
+>1234#10_00007 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
+MIVIPAIDLFDNCAVRLFKGNYEEKKIYSSEPWKLAESFAKNGATLLHLVDLNGARNQLG
+VNEDSILKIRETTSLKVQLGGGIRDKEKLAYYDKIGINRFILGTAAVTNPDLLKYALDNY
+GKERVVVAVDARDGIVKIAGWEKDSGIHYRDLLERLVKAGIEHIVFTDIAQDGTLAGPNL
+EAYREILNSYPFQVIASGGIASLKDLMDLSSLKTKISLYGVITGKALYEGKLDLAKAISS
+I*
diff --git a/t/data/example_2.faa b/t/data/example_2.faa
new file mode 100644
index 0000000..f6929ec
--- /dev/null
+++ b/t/data/example_2.faa
@@ -0,0 +1,27 @@
+>1234#10_00016 hypothetical protein
+MKVTHSCLEFDSIEGLIDFAREFETGSMIRFLSPIEDNSGNVLVKEEVQVKESTLARLKD
+IKGQYTPKFEVKLNKELLEQIQNILAIKIVNQLKVTDMKFLKFMYENTNYNFKGIIRNSL
+LSKKTTLTLLKVYNQNLNFFKYISELGLLSLGIVMIPDTMRFRLLRRYAFTAGILMDVPR
+IGVDKFTKLPSDDNEKVRVAHKCSDILQKLDLIEFTYGSISNHMPLGMIEDSTSSDKAAP
+GENIDETFLDDIISNDGESDSKVDGSREDAIPEKSYDIFQALLTDALKLARYIANVSHNA
+VDKDYVMEELVYYIAYNTSKKYFDELLANPLVATFKEFEVNVKRLRKIAEVEMKCVYPPS
+AWAYPKPKSSQVLCKNKVWDCPNIVMGWDIHVITAQEAFGWVGTSLPVDNYPKCRLEEEL
+DEIMVEPEKPKKK*
+>1234#10_00017 LipL45-like lipoprotein
+MKRYLSIVILCTFAMLLLVCSTNKSSGSDQVKTESNATSARIVWLLGDVKILSDSGEKKA
+ELGASLSSTDRVVTGPNGGAEIMVADSGIIKMSKNSDIEISSLMNPNGSDTNVQVNYGKI
+VTMVKKGQKTTEFTVSTPTALAGVRGTSFLTSVESPEGSKINCAKANCTVRFAVIEGTIA
+VSKKGESSEVILSKNRELRIEKNQKLTDKLIRSLQNDSLSEMKELIVLHKNETFEYGKLV
+EELKSSSEELKILSQSGSVEEVKAAFQKREADRNNADEITKTAKAVNETKYVQQDVQKEK
+LKLNPKETF*
+>1234#10_00018 putative lipoprotein
+MDFSFNLVDNNGTVMRSTFSPIRFFTFSFLWILIDCSSVQKIENFNSVLQEPTFKSLKEE
+EAILGGSSDSDYKIRKTGNTIPVFVLSPIQTPEGMDSKLAAFLSDEVRLIWAKVKGKQVR
+IQEMSWKNPSQLSQELKRLNVDAVIKTDIREVSGKWVVNQKITDPVKEIVYGSVDGSFQS
+PKIEDELQANQAYYLKHGSGVLALDAKSSLVPIWEKSLSSGEIDSILKKSIQGYLSFSAS
+SADTEVLFQGEKIGIASFRNYPLPEGLQQIQITRPGQKDISKSLQIRSGQTISIYQEWKE
+DRTLGGVRILSFPEALQVALDGLKMGETPFYRSNLTPGAMQLELVRETENGPLVYYEGQL
+IVDADKITEIALPYKTDNLISEPEFWKLSGEKGFQAFSGKTLDFQNVSSLPPGWYGVFSA
+PFVPENMELEGIIPITAESDSGIVAISFHTSKKTISLEYEKERLSVYSFPSNGNNVGTYK
+FKKEDKEDGRPFRIITDVKEGTIRLYLGYSKVLEDRLDVSGVWRISILTRGENFSKRSPL
+RNLKIEYKGYK*
diff --git a/t/data/example_3.faa b/t/data/example_3.faa
new file mode 100644
index 0000000..3391a10
--- /dev/null
+++ b/t/data/example_3.faa
@@ -0,0 +1,43 @@
+>3333#10_00016 hypothetical protein
+MKVTHSCLEFDSIEGLIDFAREFETGSMIRFLSPIEDNSGNVLVKEEVQVKESTLARLKD
+IKGQYTPKFEVKLNKELLEQIQNILAIKIVNQLKVTDMKFLKFMYENTNYNFKGIIRNSL
+LSKKTTLTLLKVYNQNLNFFKYISELGLLSLGIVMIPDTMRFRLLRRYAFTAGILMDVPR
+IGVDKFTKLPSDDNEKVRVAHKCSDILQKLDLIEFTYGSISNHMPLGMIEDSTSSDKAAP
+GENIDETFLDDIISNDGESDSKVDGSREDAIPEKSYDIFQALLTDALKLARYIANVSHNA
+VDKDYVMEELVYYIAYNTSKKYFDELLANPLVATFKEFEVNVKRLRKIAEVEMKCVYPPS
+AWAYPKPKSSQVLCKNKVWDCPNIVMGWDIHVITAQEAFGWVGTSLPVDNYPKCRLEEEL
+DEIMVEPEKPKKK*
+>3333#10_00018 putative lipoprotein
+MDFSFNLVDNNGTVMRSTFSPIRFFTFSFLWILIDCSSVQKIENFNSVLQEPTFKSLKEE
+EAILGGSSDSDYKIRKTGNTIPVFVLSPIQTPEGMDSKLAAFLSDEVRLIWAKVKGKQVR
+IQEMSWKNPSQLSQELKRLNVDAVIKTDIREVSGKWVVNQKITDPVKEIVYGSVDGSFQS
+PKIEDELQANQAYYLKHGSGVLALDAKSSLVPIWEKSLSSGEIDSILKKSIQGYLSFSAS
+SADTEVLFQGEKIGIASFRNYPLPEGLQQIQITRPGQKDISKSLQIRSGQTISIYQEWKE
+DRTLGGVRILSFPEALQVALDGLKMGETPFYRSNLTPGAMQLELVRETENGPLVYYEGQL
+IVDADKITEIALPYKTDNLISEPEFWKLSGEKGFQAFSGKTLDFQNVSSLPPGWYGVFSA
+PFVPENMELEGIIPITAESDSGIVAISFHTSKKTISLEYEKERLSVYSFPSNGNNVGTYK
+FKKEDKEDGRPFRIITDVKEGTIRLYLGYSKVLEDRLDVSGVWRISILTRGENFSKRSPL
+RNLKIEYKGYK*
+>3333#10_00001 nudix hydrolase
+MSKHGFFQITQKLFLRKGDELLILRDRKSGLGDLPGGRMNENEFFEDWSLSMQREIEEEL
+GSQVQIRVSTKPLFIHKHKVNEGNFPCIIIAYHADYLGGDIILSDEHDYISWEKVQTYEP
+SPLFTEYMLDAVNLYLKEYAPLVH*
+>3333#10_00003 hypothetical protein
+VKTTLSGEIEKLRYEVAVKIVNLQGEVLDLRAEMKINFSEVNSKILKLQFEFEMAKIRKE
+LKTEIADLRAETKTDFLELQKSIVDIYKTISTQTRWILGVATLFAAIGKVIN*
+>3333#10_00005 imidazoleglycerol-phosphate dehydratase or histidinol-phosphatase
+LTDKLIGFYDPVRMKAERKTSETEIKLEMNLRGTGQYQFDTEIPFFEHMLSHISKHGLID
+LNLWLRGDIEIDCHHSVEDTAILMGATIHKQLGDKAGIFRYGHFTLTMDEVLTTVAVDLG
+GRYFFKYTGPELTGKFGIYDAELSLEFLQKLALNAKMNLHVVVHYGDNKHHVHESIFKAL
+GKALRMAIAQDSAAAGAIPSTKGVLE*
+>3333#10_00006 imidazole glycerol phosphate synthase subunit HisH
+MIAILDYGMGNIHSCLKAVSLYTKDFVFTKDHSTIENSKALILPGDGHFDKAMENLNSTG
+LRKTIDKHVTSGKPLFGICIGFQILFESSEEIAQGSKKEQIEGLGYIKGKIKKFHGKDFK
+VPHIGWNRLQIRRKDKSVLLKGIGDQSFFYFIHSYRPTDAEGNAITGLCDYYQEKFPAVV
+EKNNIFGTQFHPEKSHTHGLKLLENFIRFI*
+>3333#10_00007 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
+MIVIPAIDLFDNCAVRLFKGNYEEKKIYSSEPWKLAESFAKNGATLLHLVDLNGARNQLG
+VNEDSILKIRETTSLKVQLGGGIRDKEKLAYYDKIGINRFILGTAAVTNPDLLKYALDNY
+GKERVVVAVDARDGIVKIAGWEKDSGIHYRDLLERLVKAGIEHIVFTDIAQDGTLAGPNL
+EAYREILNSYPFQVIASGGIASLKDLMDLSSLKTKISLYGVITGKALYEGKLDLAKAISS
+I*
diff --git a/t/data/example_annotation.gff b/t/data/example_annotation.gff
new file mode 100644
index 0000000..ce5e1bd
--- /dev/null
+++ b/t/data/example_annotation.gff
@@ -0,0 +1,271 @@
+##gff-version 3
+##sequence-region abc|SC|contig000001 1 15000
+abc|SC|contig000001 Prodigal:2.60 CDS 172 1131 . - 0 ID=abc_00001;gene=hly;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:Q2G1X0,protein motif:TIGRFAMs:TIGR01002,protein motif:Pfam:PF07968.6;locus_tag=abc_00001;product=Alpha-toxin,beta-channel forming cytolysin,Leukocidin/Hemolysin toxin family protein;protein_id=gnl|SC|abc_00001
+abc|SC|contig000001 Prodigal:2.60 CDS 1804 1950 . + 0 ID=abc_00002;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00002;product=hypothetical protein;protein_id=gnl|SC|abc_00002
+abc|SC|contig000001 Prodigal:2.60 CDS 1934 2131 . + 0 ID=abc_00003;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00003;product=hypothetical protein;protein_id=gnl|SC|abc_00003
+abc|SC|contig000001 Prodigal:2.60 CDS 2621 3337 . - 0 ID=abc_00004;inference=ab initio prediction:Prodigal:2.60,protein motif:CLUSTERS:PRK13350,protein motif:Pfam:PF02876.11;locus_tag=abc_00004;product=superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00004
+abc|SC|contig000001 Prodigal:2.60 CDS 3445 4170 . - 0 ID=abc_00005;gene=speH;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P0C0I6,protein motif:CLUSTERS:PRK13349,protein motif:Pfam:PF02876.11;locus_tag=abc_00005;note=SPE H;product=hypothetical protein,superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00005
+abc|SC|contig000001 Prodigal:2.60 CDS 4265 4990 . - 0 ID=abc_00006;inference=ab initio prediction:Prodigal:2.60,protein motif:CLUSTERS:PRK13043,protein motif:Pfam:PF02876.11;locus_tag=abc_00006;product=superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00006
+abc|SC|contig000001 Prodigal:2.60 CDS 5428 6429 . + 0 ID=abc_00007;eC_number=2.1.3.3;gene=argF;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P99073,protein motif:CLUSTERS:PRK04284,protein motif:Cdd:COG0078,protein motif:TIGRFAMs:TIGR00658,protein motif:Pfam:PF00185.1;locus_tag=abc_00007;product=Ornithine carbamoyltransferase,ornithine carbamoyltransferase,Ornithine carbamoyltransferase,ornithine carbamoyltransferase,Aspartate/ornithine carbamoyltransferase [...]
+abc|SC|contig000001 Prodigal:2.60 CDS 6449 7384 . + 0 ID=abc_00008;eC_number=2.7.2.2;gene=arcC1;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:Q7A627,protein motif:CLUSTERS:PRK12353,protein motif:TIGRFAMs:TIGR00746,protein motif:Pfam:PF00696.22;locus_tag=abc_00008;product=Carbamate kinase 1,putative amino acid kinase,carbamate kinase,Amino acid kinase family protein;protein_id=gnl|SC|abc_00008
+abc|SC|contig000001 RNAmmer:1.2 rRNA 7556 9112 . + 0 ID=abc_01705;inference=COORDINATES:profile:RNAmmer:1.2;locus_tag=abc_01705;product=16S ribosomal RNA
+abc|SC|contig000001 Prodigal:2.60 CDS 9419 9646 . + 0 ID=abc_00010;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00010;product=hypothetical protein;protein_id=gnl|SC|abc_00010
+abc|SC|contig000001 Prodigal:2.60 CDS 9952 10899 . - 0 ID=abc_00011;inference=ab initio prediction:Prodigal:2.60,protein motif:Pfam:PF03595.11;locus_tag=abc_00011;product=C4-dicarboxylate transporter/malic acid transport protein;protein_id=gnl|SC|abc_00011
+abc|SC|contig000001 Prodigal:2.60 CDS 11148 11336 . + 0 ID=abc_00012;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00012;product=hypothetical protein;protein_id=gnl|SC|abc_00012
+abc|SC|contig000001 Aragorn:1.2.34 tRNA 11803 11878 . - 0 ID=abc_00013;inference=COORDINATES:profile:Aragorn:1.2.34;locus_tag=abc_00013;product=tRNA-Arg(tct)
+abc|SC|contig000001 Prodigal:2.60 CDS 12241 12375 . + 0 ID=abc_00014;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P11699,protein motif:Pfam:PF05480.5;locus_tag=abc_00014;product=Gonococcal growth inhibitor III,Staphylococcus haemolytic protein;protein_id=gnl|SC|abc_00014
+abc|SC|contig000001 Prodigal:2.60 CDS 12432 12566 . + 0 ID=abc_00015;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P11699,protein motif:Pfam:PF05480.5;locus_tag=abc_00015;product=Gonococcal growth inhibitor III,Staphylococcus haemolytic protein;protein_id=gnl|SC|abc_00015
+abc|SC|contig000001 Prodigal:2.60 CDS 12699 13385 . + 0 ID=abc_00016;eC_number=3.-.-.-;gene=yfnB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:O06480,protein motif:CLUSTERS:PRK09449,protein motif:TIGRFAMs:TIGR02254,protein motif:Pfam:PF00702.1;locus_tag=abc_00016;product=Putative HAD-hydrolase yfnB,dUMP phosphatase,HAD hydrolase,haloacid dehalogenase-like hydrolase;protein_id=gnl|SC|abc_00016
+##FASTA
+>abc|SC|contig000001
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
+ATACCCACCACATTTGGTGGAGAACCAAAAATTAGCCGAAAAACATCATTTCTGAAGTTA
+TCGGCTAAAGTTATAAATTATATTTATTTGTACATGAACAAATAATTTACATTAATTTGT
+CATTTCTTCTTTTTCCCAATCGATTTTATATCTTTCTGAAGAACGATCTGTCCATTTATC
+TTTAGTATTGGTACCTTTCCAATTTGTTGAAGTCCAATGCAATTGGTAGTCATCACGAAC
+TCGTTCGTATATTACATCTATATTTGTTTGTTGTTTGGATGCTTTTCTATCCATAGTAAT
+AACTGTAGCGAAGTCTGGTGAAAACCCTGAAGATAATAGAGAACTTGCTTTGTTAGGATC
+AAGGAAGTTCTCTGCTGCTTTCATAGAACCATTTCTAGTTTTCATGAAAAGTTGATTGCC
+ATATACCGGGTTCCAAGAATCTCTATCATATGGTCCCCAATTTTGATTCACCATATTGTT
+AAATATCACTTTCCAGCCTACTTTTTTATCAGTTGGGCTCTCTAAAATTGTTTTGAAATC
+AGGTTGAACATATTTCAGTGTATGACCAATCGAAACATTTGCACCAATAAGGCCGCCAAT
+TTTTCCTGTATCATCACCAGTAACATTACCGTTGAATCCATAAGTTAAAGTACTCATATA
+CTCTTTTGTATCAATCGAATTTCTTGGATAGTAATCAGATATTTGAGCTACTTCATTATC
+AGGTAGTTGCAACTGTACCTTAAAGGCTGAAGGCCAGGCTAAACCACTTTTGTTAGCACC
+TTCTTCGCTATAAACTCTATATTGACCAGCAATGGTACCTTTCGTTCTAATAACTAGCAG
+TTTTTTATTGTGATTTTTATCATCGATAAAACTATAAAATACTTTTTTGTGCATGCCATT
+TTCTTTATCATAAGTGACTAAATCACCTGTTTTTACTGTAGTATTGCTTCCAATATCTGT
+AGTACCGGTTTTAATATTAATATCAGAATCTGCGGCATTAGCGACAGGATTCATTAATAT
+GGAACCTAGCAATAGTGTTGTTGTTACTGAGCTGACTATACGTGTTTTCATTTTCATCAT
+CCTTCTATTTTTTTTAACGATTTGAGGAAACAATAATCAATATGTCAATTTAGAATATTG
+CAGTTGAGACATATCAAATATTTATAATCGTTTATATTAGTATATTTAATGTAGCAACTG
+ATAAATTACTGAGTGATGATGAGTGATTATTTTAAGAATATGTTTTTAACTTTTATTTAA
+AATTTGAAAGGAAGCATTTCAATTTCGAGGGTTAGTCAAAGTTGAATAAATTCTTTATGA
+AACAAGGAAAAGACATAGCTAATTTTATTGATTAATTTCTTTAAAACTAATGATTTGTTT
+GATTTAAAAATGTAATCGATTACAATATAAAAATACAAATATCTTAGAATTAAATCAATT
+AATTAACTATTAAATAAAAATTAAATATATATTAACTACTGTAAATTAATAAATAGAAAT
+AGAGAAAAAGGGTATTAATTATGTTTGGAATTTCGTCGGGAATAATTTTTGCCATTACAT
+AGAAATATCTAATAGATAATGAAAAAGTATCGTATGTATTTTTAATATAGTGTAAAATAT
+CATATGTAAAATAAAATGTAGATTTTTAGTTAGAGGCATTATAAGAAAATTTTGAGTATA
+GGTTAGCTTTTAATTATGAATCTTATTGAAATTTGATTAATAAATATATGATAGGGGATT
+AAAATGAAACTATTTTATATCGTATTTCTTATTATTATATGGCTGAATATATTTTTAGGA
+AATGAAATTATCCATACACTGACTGTTTTAATAACAACATTGTATATTGTTAATTCAAGA
+AAGGGGATTAAAAATGACAGAGTTGAATAATATTATAAACTCTCTTCAATCTTTGTTTGA
+GTCTGAATCAGGCTATAAAATTTCGAAAAATTCAGGAGTTCCATATCAAACAGTACAAGA
+TTTAAGAAATGGGAAAACCAAACTAGAAGATGCTAGATTTAGAACGATTATTAAACTTTA
+TAGTTACTATGTCTCATTAAAAGAACATTAATCATGGGACAATAAAGTATTGCTATAATA
+ATTGAATCATTAAATGAAGGAATAGAGCCTAAGACATAATAAATCAATGTCTTAGGCTCT
+ACAATATTATATTGGTAGTAGTTGACCGAATGAAAATGACCATGTAACAAGCATTTTTGG
+GGCCCCAACACAGAAGCTGACGAAAAGTCAGCTTACAATAATGTGCAAGTTGGGGATGGG
+CCCCAACACAGAGAATTTCAAAAAGAAATTCTACAGACAATGCAAGTTGGCGGGGCCCCA
+ACATAGAGAAATTCAAAAAGAAATTCTACAGACAATGCAAGTTGGGGAGTGACAACGAAA
+TAAATTTTATAAAATACCATTTCTGTCACATTCCTACTCCCAATTCCATTTAAATATATA
+GAAAATTTCACCTATTATATACATCATACACTTTAAAAATTATCATTTAAATAATCTGAT
+TTGGAATTAAAGTGCATGAAGTATAAGTCACCTTCATATACTAATCAAAGAGGACGTCAA
+CAGTTATTTTATTAGGATTTTTAACATAAACATTTGCTAGATCTGAATGTAATCTTTTGC
+TTAAATCAATAGTGTAGTTATTACCGCCACCGGTGATCTTAAGCTTACCTTTATTACGAT
+TTTCGGTATATAATATTTTATTTTTTATTAACGCTTCTCGTGCACGGAAATCGATTTCTT
+TCAATGTTAATACTGGTTTATTGCCTTGGTATATTTTATGCGCACCAATAATCGTTTGTA
+GTTTATCTTTGTATTGCACAAAAAGATTATAAGTTTTATCAGAAGGTTTTGCGGCTGGTG
+TAACGCCACCTGTAAATGTCTCTCTATAAGACCACCATAACTGATCAGTATCTTTGTCTT
+TTAGTCCAAACACATCTACGTAACGATCTTTTAACTGATTAATATTTCCCCAACTTTCAG
+CGCCCCATAAAGATATATGTGCTGACCATGAATATCTCTTAAGTTCAACATAAATGTTTC
+CATTATCATATTGATATAGCCATTTATTTGAAAATGAAAAATGAGGCTGTGTGTAATATT
+TAATTAATTCATTGATGTTAGTTTCATCTTGACCAATGCTATAAGCTTTAGCTTCAGAGT
+AAAAACTAAATACTGGTTTTTGATTTTGAGGTAATACAGTACCTAATAGTAATAATGTTG
+TCGTTAAAATTATATTTTTCGTGATGTTCTTACTCATTAGAACATCTCCTTTCAGAGGAA
+TCATGATACGAGGAATAAGAAATTTAAATGTGAGCGAAGTCAATATAGTATTTGCGATTA
+TTTTTATTAACTCCATTATTATTGTTAGTTTGATTTTTCGAGGATAACTTCAATTTTTGC
+ATTTTGAGGTTTTTTAACATATCTATTTGCATCAGTTGATGGCAACCTTTTACTTAAATC
+TATTGTGTAGTTATTGTCTGTACCTGTTATTTTAATTTGTCCTTTATTATAAGAATTATT
+ATATAATTTTTTACTTTTAATTAATGTTTGACGAATACGAAAATCTAATTCTTTTAAAGT
+TAAAACAGGCTTATTGCCTTCATAAACTGGAAATCCGCCAGTAAACGTTTCTGCTTTATC
+TTTATATGTTACATTCAGTTTATAGTGTTTATCGTTAGATGTTGCTGCAGGAGTAACACC
+ACCAGTAAACGTTTCTTGAGATAATGCAAAAGAATCAATGGTTTCTTGGTCTTTTATGCC
+AAAAATATCAACGCTTTTATTTCTTAATTGGTTGATATTGCCCCAACTTTCAGGTCCATA
+AACTTGAATATGACTATACCAAGAAAACTGTAACAACGTTGCATGAATCGTACCGTTATC
+TTTTTGCCATAACGTACTGTTAGAGAAGGTTAAATATTTTTGCGAGTAATATTTAGTTAA
+CTCATTAACGTTAGTTTCGTTTTGATTTATATAATAAGCTTTCGCTTCAGATGAAGAATT
+GATAGGTGTATTAGGAAATTGTGTAAATGCTGTACCTAATAGTAACAATGTTGTTGATAA
+AATAATTTTTTTCGTGATGTTATTGTTCATTCGAATTTCTCCTTTGAGTATTGTTGGAAT
+GTTTAATTATAAAAAGGGGTTAATTAGATAATTGAAATTATCCGCATTTACAAAAGGTAA
+TAGGTTAGTTAGATTTTTCGAGTATGACTTCAATTTGTGCATTTTTAGGATTTTTAACAT
+AACGGTTTGTGTCAGTTAATTTTAACTTTTTACTTAAATCAATCGTGTAATTATTTCCAT
+CAGCAGTTATCTTAATTTGACCTTTATTAAATTCTCCGTTATATAACTTTTTATTCTTTA
+TTAATGTTTGACGAATACGGAAATCTAATTCTTTTAAAGTTAATACTGGTTTATTTCCTT
+TGTAAAATTCATGTCCACCGATGATAGTTTGTTGTTTATCACTATATTTTAAAAATAGTC
+TATAAGGTTTATCAGATGAAGTAGCTGCTGGCGTAACACCACCAGTAAATGTTTCATCAT
+AAGTCCAGTAACCTTCAACTGTGTCCTCATCTTTAGTTCCAAATATATCAACGTATTTAT
+TTCTTAACTGATTAATGTTTCCCCAACTCTCGGATCCAAACACTTGAATATGACTATACC
+AAACCCACGTTTGCAATGTTGCATGAATGCTACCATTGGGCTTTTGCCATAGCCATTTTC
+CAGATAATGAAAAATGCGGCTGAGTGTAATATTTGATTAACTCATTGATATTAGTCTCGT
+TTTCACTGATATTATAGGCTTTTGCTTCAGATGAAAAACTGATTGGTGTTTTAGGAAGTT
+GTGTTGATGTGGTTCCTAAAAGTAACAATGCTGTTGATAAAACTAATTTATTCATGATGT
+TCTTTTTCATATGAAAATCTCCTTTGCGTGAATTACCCAAAGTATATAAGCTATTACACC
+GATTCGGAATTAAATAAAAGCTAAAACTATGTTAAATAAACTTAAACAGTTAGTAGTGTT
+ATTTAAGCAAAACTTATCATTTTTAAGTTTTGGACAGAAACAGTACTTAATAAAGTAGGC
+GGGAGTTATATATTAAAAACGACACGTTACAATTATTCTCTAATCAATTGCATTAAATTG
+TTTGATAATTGAATTTTCTAACTACTTGAAAAATAGTTATACTTTAAATGTAGTACTTAT
+TTTAATTATTTCCTACTACTTAAATTTAATATTAATAAAATGTTCATTTAATTATTGATA
+AAATATTACAAATTTTAATAGTAGGTTGTGTTTATTTTGTATGCGCTTACAATTTAGGTG
+TAACTAAAATAAAAGGAGTTGTTATTAATGAAAAATTTACGAAACAGAAGTTTTTTAACT
+TTATTAGACTTTTCACGACAAGAGGTAGAATTCTTATTAACACTCTCCGAGGATTTAAAA
+CGTGCTAAATATATTGGCACTGAAAAGCCTATGTTAAAAAATAAAAATATTGCACTGTTA
+TTTGAAAAAGATTCTACAAGAACGCGATGTGCATTTGAAGTTGCAGCGCATGATCAAGGT
+GCAAATGTAACTTATTTAGGCCCAACTGGATCACAAATGGGTAAAAAAGAAACAACTAAA
+GATACTGCACGTGTGCTTGGTGGAATGTATGATGGCATTGAATACCGTGGTTTTTCACAA
+AGAACAGTAGAAACTTTAGCTGAAAATTCAGGCGTACCAGTGTGGAATGGTTTAACTGAT
+GAAGATCATCCTACTCAAGTTCTTGCTGATTTCTTAACAGCAAAAGAAGTCTTAAAAAAA
+GATTATGCAGATATTAACTTTACATATGTTGGAGATGGTCGTAATAACGTTGCAAATGCA
+TTAATGCAAGGTGCTGCCATTATGGGTATGAACTTCCATTTAGTTTGTCCAAAAGAATTA
+AATCCAACAGATGAATTATTAAATCGCTGTAAAAATATTGCCGCTGAAAATGGTGGCAAC
+ATATTAATCACAGATGATATTGACCAAGGTGTAAAAGGTTCGGATGTAATTTACACTGAT
+GTTTGGGTATCAATGGGTGAACCTGATGAAGTATGGAAAGAACGACTTGAATTATTGAAA
+CCATATCAAGTAAATAAAGAAATGATGGATAAAACTGGTAATCCAAATGTTATTTTTGAG
+CATTGCTTACCATCTTTCCATAATGCTGATACGAAAATTGGTCAACAAATTTTTGAAAAA
+TATGGTATTCGAGAAATGGAAGTTACAGATGAAGTATTCGAAAGTAAAGCTTCAGTTGTA
+TTCCAAGAAGCTGAGAACAGAATGCATACAATCAAAGCAGTCATGGTTGCTACATTGGGT
+GAATTTTAAATGATATAAGGAAGTGAATATGATGGCGAAAATAGTAGTAGCATTAGGTGG
+TAATGCTTTAGGAAAATCACCTCAAGAACAACTCGAGCTTGTTAAAAATACTGCGAAATC
+ATTAGTAGGATTAATAACAAAAGGACATGAGATTGTTATTAGTCATGGTAATGGACCACA
+GGTTGGAAGCATTAATTTGGGACTTAACTATGCTGCAGAACATAACCAAGGTCCGGCATT
+TCCATTTGCTGAATGTGGCGCAATGAGTCAAGCTTACATCGGCTATCAATTACAAGAAAG
+CTTACAAAATGAATTGCATTCTATTGGAATGGATAAACAAGTGGTAACACTAGTGACACA
+AGTTGAAGTTGATGAAAATGATCCGGCATTTAACAATCCTTCAAAACCAATTGGGTTATT
+TTACAACAAAGAAGAAGCTGAACAAATTCAAAAAGAAAAAGGATTTATATTTGTTGAAGA
+TGCTGGAAGAGGATATAGACGCGTTGTTCCTTCACCACAACCCATCTCTATTATTGAATT
+AGAGAGTATTAAAACACTTATTAAAAATGATACACTCGTTATTGCTGCTGGTGGTGGAGG
+TATACCAGTAATTAGAGAGCAACATGATGGTTTTAAAGGTATTGATGCAGTTATAGACAA
+AGATAAAACAAGTGCGTTGTTGGGTGCTAATATTCAATGCGATCAATTGATTATTTTAAC
+AGCAATTGATTATGTATATATTAATTTTAACACTGAAAACCAACAGCCTTTGAAAACAAC
+AAATGTTGATGAATTAAAACGATATATAGACGAAAATCAATTTGCAAAAGGAAGTATGTT
+ACCAAAAATTGAAGCAGCCATATCATTTATTGAAAACAATCCAAAAGGAAGTGTGCTTAT
+AACATCATTAAATGAATTAGATGCTGCCTTAGAGGGTAAAGTAGGTACTGTGATTAAAAA
+GTAATTGAATTGAAACGCTTTTCAATTACTATATGTCAAATGCATGATTTTTATTATTTA
+TGTGCACCCCCTGAAAATAATGCCTCTATTTTGATGCGGGGTGCACTTTCTTAATTTATA
+TTTATAAAATCTTTAAGGTAGAAATGCTAGGTTAAATGTCGAAGGAGATGAAACCGTGGA
+AAATACAATTAATGAAAGTGAAAAGAAAAAACGATTTAAATTAAAAATGCCAGGTGCATT
+TATGATTTTATTCATTTTAACGGTTGTTGCAGTTATAGCAACATGGGTTATTCCTGCTGG
+TGCATATTCTAAACTTTCTTACGAACCTTCATCCCAAGAACTAAAGATAGTTAACCCTCA
+TAACCAAGTGAAAAAGGTTCCGGGTACGCAACAGGAACTAGACAAAATGGGGGTTAAAAT
+TAAGATTGAACAATTTAAATCAGGTGCAATTAATAAGCCAGTATCAATTCCGAATACTTA
+TGAAAGATTAAAGCAACATCCAGCTGGACCAGAACAAATAACAAGTAGCATGGTTGAAGG
+TACGATAGAAGCGGTCGATATCATGGTATTCATTCTTGTACTAGGGGGACTTATTGGCGT
+AGTTCAAGCCAGTGGTTCTTTTGAATCGGGATTGTTAGCTTTAACGAAGAAAACAAAAGG
+GCATGAATTTATGCTAATTGTGTTTGTATCAATACTAATGATTATCGGCGGGACGTTATG
+TGGTATTGAAGAAGAAGCTGTAGCATTCTATCCGATTTTAGTCCCTATATTTATAGCGTT
+AGGATACGATTCTATCGTTTCAGTTGGTGCCATATTCCTTGCCAGCTCTGTCGGTAGTAC
+ATTTTCAACTATTAACCCGTTCTCGGTTGTAATTGCCTCTAATGCCGCTGGTACAACTTT
+TACGGATGGCTTGTATTGGAGAATAGGTGCTTGTATTGTCGGTGCGATTTTTGTTATTAG
+TTATTTATATTGGTACTGTAAAAAAATTAAAAACGATCCTAAAGCGTCATATTCTTATGA
+AGACAAAGATGCTTTTGAACAGCAATGGTCTGTATTAAAAGATGACGATAGTGCCCATTT
+TACTTTGCGTAAGAAGATAATCCTTACATTATTTGTACTACCATTTCCAATTATGGTATG
+GGGAGTTATGACGCAAGGTTGGTGGTTCCCAGTTATGGCTTCAGCATTTTTAATATTTAC
+AATTATAATAATGTTTATTGCTGGGACAGGTAAATCTGGATTGGGAGAAAAAGGAACTGT
+AGATGCATTTGTCAATGGTGCATCAAGTTTAGTAGGTGTATCTTTAATTATTGGTTTAGC
+TCGAGGTATTAATTTAGTGTTGAATGAAGGTATGATTTCAGATACAATCTTACACTTTTC
+ATCATCTTTAGTTCAACATATGAGTGGACCATTATTTATCATCGTATTACTATTTATTTT
+CTTCTGTTTAGGTTTTATCGTGCCATCATCTTCTGGATTAGCGGTATTATCAATGCCTAT
+CTTTGCACCACTAGCTGATACAGTAGGTATACCAAGATTCGTCATCGTTACGACATATCA
+ATTTGGTCAATATGCGATGTTATTCTTAGCGCCGACTGGACTTGTTATGGCCACACTACA
+AATGTTAAACATGCGATATTCACATTGGTTCCGATTTGTATGGCCGGTAGTTGCTTTTGT
+ATTGATTTTCGGTGGCGGAGTACTAATTACGCAAGTACTAATTTATTCATAATTTGAAAT
+GCTATATTATAAAAATACTAATTGGGTTTTATGCATCTCGTAGGTTTGTAGAAATACTAA
+ACTAAGCGAGGTGCATTATTATTTTTGATTAAGAAAATAATGACGGTAATGATAACACTA
+GTAAGTAATTGATACAATGCTCTATTTAATAATGATATTTTTAAAATTTGTTTTTAATGT
+AATGTTAGATCTATGGTATATTATATTTATCGTGGTAAATATGTATTTGCTGTAAACAGT
+TTTTGTAACACATGACACATATGGTTGTGAAAATAGCATATATAAAGGATGGCTATAAAT
+GACACATTTGACAAAGGTTTTAGATACACTAACTGGAATATGCGTAGTATTATTATTTAG
+TAAATATTTTGTGGCGTATGCAAATATGGTGTTTGATTGGAATTTAAGATGGTATTTGCT
+AGAAAACATACCACATTTGCCAATTATATTATTTATTCTGATGTTTATTTTCGGAGTACC
+TTCTGAAATGATAAAAGATAGGCAAAGGAAAAATAACGGTGTTTAATTTATCGATATTTA
+GAGGTGATAAAATTTGTCAACTATTACAAAGACTAAAATAAAAATCTTTATTAATTATTT
+TATTGGTATATTAGCCTTGGCGTTTGCTGCTTATATATTATTTAAATAAAGGTTAGAGTG
+AAACGTGTTTATGAACTAGACGTTCTAGTATAGTTACTACAGCTTTAGTCAGAAGGTATC
+ATTGATAAGATCATATTAAATCAAAGAGGCATTGATATACACTAAAAAGAGGCAAGATTA
+CCTGCCTCTTTTTTAGTTATTAAATATGCGTGTTAATTCTTGGTAATAGTGTTACTGAGA
+CGCATTACGAAGAAATTTATCTTGATTTTCCTTTTTTAAAAAGAAGTGAAGATATCCTAT
+AAAGACTCTAAGTACTATTACAGTGGCTAATAACACTTCGATAAACAAAAGACCTTTCCA
+AATATCTGGAAACATAAGTACAGGCAAACTGTTCTTTAAAGCAGTTGCTGAGATTACTAA
+AGGGAATGTGAAAGCTGAAAATACGGGCGAAAAAGGTTCTTTTAGTAATTTAGGCAATTG
+TATAATGATATAAAAATAAAATATTTGAGCTAATATTAAAAATATAATTACGATAAAAGC
+ATTCGCCTTAGGAAAGGCTATAACATATGCTGCAGCGACTAAAGAAAATGGTGCACAAAT
+TGTCGATGTGTTCGGTTTGATTGACGTCTGCAATGGAAATGCTTTTAATCGCTTGAAAAC
+AATAGGTAAGACAATACAAGTAGCTACAAAGCCATATATTACTGTTAATTGACCTATGAA
+AAAACATCCGCTAACGGGTGCCGTCAATCCTGCGATAGCAATACCAATAAAAAGTACAGT
+CCACGAAGGATAAACATTTTCAAGTGAAAAATCTTTTAAATATTTTATTGAAAAAATAAT
+CATATGCGTCATAATTCCCACAAGGCATAAAATCCAAATAGGCGTTATTAAGCTATTGAT
+AAAAGTTATGTTACTAAAAAATGTATTTAAATAAGTAGTACCTAAAAAGCCAGACATGAA
+AAATGTTGTGAACACTGATGAAACTAGAGGACTGTTTAATTGTTCTTTCACATTATTAAA
+ATATTTGATCATAGTACATAAAAGGTGAATCCAAATCAAGAAAGCAAAGATTCCGCAAAC
+AGCGTTTAAAGTAAGAGATAAGTCTTTTAATAGATTACCCAGGCCTAATAATCCTAAGAC
+TAGTCCTGACGTTACTAGAGGTGCTTTTTGAAGTCTCATGATTTACAACCTTTCTTATGT
+GATTTTCTTCACTAATTATATCATGATAGCTATGGCCAATTAATAAGAAGAGTGTGTACT
+ATTACGTTATTAGAGTATGTATATTGGATTGATAGACACATAATTGACATTTAAATCTCA
+AAATTAATGATATTTGAGGTATGCTTTGCAACCTAAATATTGGAATATGTGGAAAAGTAA
+TTATTTAATTTAAATGATGATTGAAGATTTACAAGGGGGTGTACAAAATGAGAAATCAAA
+TTCAAAAACTATTAGACAGTGATTTGAGCAGTTTACATATATCGAAACAAACAGGAGTTC
+CACAAAGCACAATACACAGAATGAGAAAAAAAGAAAGATCATTAGACAATATGTCATTGA
+AAAACGCTGAACTACTTTATAAATTTGCCAATAGTATATTTAGCAATGAAAATTAAGAAG
+AATAATTAGTGAGTTAAATAATTAAAAAACCACGTCTCGATGGACGTGGTTATTTTTTTA
+AATGTATTTAATTATAGGATTTCGGGCCCCTGAAAAGTCCCTAAAATTTTGAATAGTATC
+AAAATCTATAGGAATAATATAATAATAAAAATCTCTACGCATGCAAATGGTGAGTGTTAA
+AAATCTTGGTGTAGTGTTGGTGTAGTTCAGGTGCAGTATAGATGAAATTTGAGCACAAAA
+TTACTTAATTAAAAATGTATAAACAAGTGTCAGACGCGTGTCAATTGTGTGTCAAAAAAT
+TCTATGACGAATAAGCATGCTTGTTTTAATTACTGTATTTTCGGGGCTTATGCGGGGGAC
+GTTTTGGTGACGCATCATACTATATTACTGAAATTCAAAACAAAAAGAGCCCCGTAATCA
+CGGAACTCTTTTGTTTGGTAATGCGTATAAAAATACCTATAAACGTCCTGGGAGGGATTC
+GAACCCCCGACCGATGGCTTAGAAGGCCATTGCTCTATCCAGCTGAGCTACCAGGACACG
+TTTAACAACACAAGAATTATTATATCTAAATGAACTTAAATTAGCAATACCTTGTAAATA
+AAAAATGTTTATATTTTTCACTATTATAGAGCTATTTATCTAAAAAGGTTCAATAAGACT
+TAAATGCGAATTCAGGCAACTTAATTGTGTTAAATACAGTTTTGAATGCCTAACTGTATT
+TCTTTTCTCTTTAAAATACAGTTAAGTACATTATAAGATGTTGTGCGGATAAACAAACTA
+ATTGCATCAAATTTATTTTAAAATAACAACAACAAAACGTTAAGCGAATAACATTTCGGT
+GATTTAAAAGCTACGCACGTTTTTGTTATCTTCAAATTTAAATTTTAAGGAGTGTTTTCA
+ATGGAAGGTTTATTTAACGCAATTAAAGATACCGTAACTGCAGCAATTAATAATGATGGC
+GCAAAATTAGGCACAAGCATTGTGAGCATCGTTGAAAATGGCGTAGGTTTATTAGGTAAA
+TTATTCGGATTCTAATTTCAATATGTTATGTAAGTAATCAGTATTATTTCAAAGGTGAGG
+GAGAGATTTAAATGACTGGACTAGCAGAAGCAATCGCAAATACTGTGCAAGCTGCACAAC
+AACATGATAGTGTGAAATTAGGCACAAGTATCGTAGACATCGTTGCTAACGGTGTGGGTT
+TACTAGGTAAATTATTTGGATTCTAATATAATAACTAATATTCTTTAAAATAAACTGGGT
+GAGCATACTTTAATGTTATGCACTCAGTTTATTTTATTTGCAGAAATTTGAGCCTCTGTT
+AAGATTTAGATACATAGACAATATAGGAGATGGGGAAATTGGGATATAAAAATATTTTGA
+TAGACTTTGATGATACAATTGTTGATTTTTATGATGCAGAAGAATGGGCGTTTCACTATA
+TGGCGAATGTTTTTAATCATAAAGCAACAAAGGATGATTTTTTAACATTTAAAAAAATCA
+ATCACCAACATTGGGAAGCTTTTCAACAAAATAAATTAACGAAGTCTGAAGTATTATCAG
+AACGATTTGTGAATTACTTCAAACATCATCAAATGGAAGTTGATGGGCATCGTGCAGATG
+TGTTATTTAGAAATGGATTAGCAGAAGCTAAAGTTAAATACTTTGATCAAACATTAGAAA
+CAATTGTCGAATTATCGAAAAGACATGATTTATATATTGTTACTAATGGTGTAACCGAAA
+CGCAAAAGAGAAGGTTAAATCAGACGCCGTTGCATAAATATATTAAAAAGATATTTATAT
+CTGAGGAAACAGGATATCAAAAACCTAATCCGGAATTTTTTAATTATGTTTTTAATGATA
+TTGGTGAGGATGAAAGACAGCACTCGATTATAGTTGGAGATTCTTTAACATCTGACATTC
+TAGGTGGAATCAATGCGGGTATAGCTACTTGCTGGTTTAATTTTAGAGGATTTGATCATA
+ATCCAGGAATTATACCTGATTATGAAATTAATTCATGGAAACAACTAAATGATATTGTAC
+GTTAAGACAAATAATTTGAAAATGATTTATATTAGCTTAAGAAAGTAATTGTAAAAACGA
+CACTACGAAAAGATGCATTTTCATGCTCGTAGTGTCGAATATTATTATCTTATGGTTTCC
+ACAATAAGACATCATGTCCCTCTATATTTTTAGCTTCCACATCTGTAAATCCATGATGTA
+AAAAGAAATCCTTAGAATCATTTCTGCCAATGGCTTTAATTGGCATATTGAAACTCTTTG
+CAAAATCAATCAATTCTGAAGCGTACCCTCTGTTTTGATATTTTGGTAATACTTCTAACT
+TCCATAATAATATATAATCTTCAAAATCTGGGAAGTAGATTTCTTCGACATCACCTTTTT
+TTAGTAATGCCATTCTAGCTCCTAATTGATCTCCGACAAATATGCCATAAAATGGTGAAT
+CTGAACTTGCATCAATCATTTGACCGTTTAACTCATTGACCATGTATAAGTCTTTGTTGC
+CAAACGCTCTAAAGTTTTCGAATAATTCGTCAGTTTTGTAATTAATTTCAAGACGTTTGA
+TTTCACTCATATTTATCTACCCCTTATTTGTTTACTACTATTATTATACATTAAACCACT
+TGTGTTTTTCATTGATTTGAAAATGTAAAACAATGAACATTATAAATTTTCCATGATTAA
+ATTGATTTTCAAGCCGTAAAATTGTCAATCACCGGTATAGACTTTATACTATAGTTTGTA
+ATCGCGTACTTAAGGAGAAAAAACATGGACTGTAAAGTAGTTAGTTTAAATGAAAAAGAT
+CAGTTTATACCAAAAATAAAGAGCAGTGACCCTGTAATAACAGGATTATTTCAATATGAT
+GCAGCTCAACAAACTAGTTTTGAAAAAAGGATGTCTAAAGAAAATAATGGAAGAGAAGCG
+GCATTAGCGAATGTTATTCGTGAATATATGAGTGATTTAAAGCTTTCAAATGAACAAGAA
+TTAAACATACAACATTTAGCTAATGGTTCAAAAGTTGTGATTGGTGGACAACAAGCAGGG
+CTTTTCGGGGGACCATTGTATACATTCCATAAAATATTTTCAATCATTACTTTATCTAAG
+GAATTAACGGATACACATAAGCAACAAGTAGTACCAGTTTTTTGGATTGCAGGAGAAGAT
+CATGATTTCGATGAAGTGAATCATACATTTGTTTATAACGAAAATCATGGGTCGCTGCAT
+AAGGTTAAATATCATACAATGGAGATGCCAGAGACGACAGTCTCTAGATATTATCCTGAT
+AAGGCTGAGTTGAAACAAACTTTAAAAACGATGTTCATTCATATGAAAGAAACTGTTCAT
+ACACAAGGTCTACTGGAGATTTGTGACAGAATTATTGACCAATATGACTCGTGGACTGAT
+ATGTTTAAAGCACTACTGCATGAAACATTTAAAGCATATGGCGTTCTATTTATAGATGCG
+CAGTTTGAGCCGTTAAGAAAAATGGAAGCGCCTATGTTTAAAAAGATTTTGAAAAAACAT
+CAGTTGCTTGATGATGCTTTTAGAGCAACACAACAACGTACTCAAAATCAAGGCTTGAAT
+GCGATGATACAAACAGATACAAATGTTCATTTATTCTTACATGATGAAAATATGCGCCAA
+TTAGTTTCGTATGATGGTAAGCATTTTAAATTAAATAAAACAGATAAGACATATATAAAG
\ No newline at end of file
diff --git a/t/data/example_annotation.gff.proteome.faa.expected b/t/data/example_annotation.gff.proteome.faa.expected
new file mode 100644
index 0000000..78f8a5d
--- /dev/null
+++ b/t/data/example_annotation.gff.proteome.faa.expected
@@ -0,0 +1,75 @@
+>abc_00001
+MKTRIVSSVTTTLLLGSILMNPVANAADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGM
+HKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNE
+VAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFK
+TILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAAENFLDPN
+KASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKW
+TDRSSERYKIDWEKEEMTN*
+>abc_00002
+MKLFYIVFLIIIWLNIFLGNEIIHTLTVLITTLYIVNSRKGIKNDRVE*
+>abc_00003
+MTELNNIINSLQSLFESESGYKISKNSGVPYQTVQDLRNGKTKLEDARFRTIIKLYSYYV
+SLKEH*
+>abc_00004
+MSKNITKNIILTTTLLLLGTVLPQNQKPVFSFYSEAKAYSIGQDETNINELIKYYTQPHF
+SFSNKWLYQYDNGNIYVELKRYSWSAHISLWGAESWGNINQLKDRYVDVFGLKDKDTDQL
+WWSYRETFTGGVTPAAKPSDKTYNLFVQYKDKLQTIIGAHKIYQGNKPVLTLKEIDFRAR
+EALIKNKILYTENRNKGKLKITGGGNNYTIDLSKRLHSDLANVYVKNPNKITVDVLFD*
+>abc_00005
+MNNNITKKIILSTTLLLLGTAFTQFPNTPINSSSEAKAYYINQNETNVNELTKYYSQKYL
+TFSNSTLWQKDNGTIHATLLQFSWYSHIQVYGPESWGNINQLRNKSVDIFGIKDQETIDS
+FALSQETFTGGVTPAATSNDKHYKLNVTYKDKAETFTGGFPVYEGNKPVLTLKELDFRIR
+QTLIKSKKLYNNSYNKGQIKITGTDNNYTIDLSKRLPSTDANRYVKKPQNAKIEVILEKS
+N*
+>abc_00006
+MKKNIMNKLVLSTALLLLGTTSTQLPKTPISFSSEAKAYNISENETNINELIKYYTQPHF
+SLSGKWLWQKPNGSIHATLQTWVWYSHIQVFGSESWGNINQLRNKYVDIFGTKDEDTVEG
+YWTYDETFTGGVTPAATSSDKPYRLFLKYSDKQQTIIGGHEFYKGNKPVLTLKELDFRIR
+QTLIKNKKLYNGEFNKGQIKITADGNNYTIDLSKKLKLTDTNRYVKNPKNAQIEVILEKS
+N*
+>abc_00007
+MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTR
+CAFEVAAHDQGANVTYLGPTGSQMGKKETTKDTARVLGGMYDGIEYRGFSQRTVETLAEN
+SGVPVWNGLTDEDHPTQVLADFLTAKEVLKKDYADINFTYVGDGRNNVANALMQGAAIMG
+MNFHLVCPKELNPTDELLNRCKNIAAENGGNILITDDIDQGVKGSDVIYTDVWVSMGEPD
+EVWKERLELLKPYQVNKEMMDKTGNPNVIFEHCLPSFHNADTKIGQQIFEKYGIREMEVT
+DEVFESKASVVFQEAENRMHTIKAVMVATLGEF*
+>abc_00008
+MMAKIVVALGGNALGKSPQEQLELVKNTAKSLVGLITKGHEIVISHGNGPQVGSINLGLN
+YAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVDENDPA
+FNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVPSPQPISIIELESIKTLIKN
+DTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDYVYINF
+NTENQQPLKTTNVDELKRYIDENQFAKGSMLPKIEAAISFIENNPKGSVLITSLNELDAA
+LEGKVGTVIKK*
+>abc_01705
+VENTINESEKKKRFKLKMPGAFMILFILTVVAVIATWVIPAGAYSKLSYEPSSQELKIVN
+PHNQVKKVPGTQQELDKMGVKIKIEQFKSGAINKPVSIPNTYERLKQHPAGPEQITSSMV
+EGTIEAVDIMVFILVLGGLIGVVQASGSFESGLLALTKKTKGHEFMLIVFVSILMIIGGT
+LCGIEEEAVAFYPILVPIFIALGYDSIVSVGAIFLASSVGSTFSTINPFSVVIASNAAGT
+TFTDGLYWRIGACIVGAIFVISYLYWYCKKIKNDPKASYSYEDKDAFEQQWSVLKDDDSA
+HFTLRKKIILTLFVLPFPIMVWGVMTQGWWFPVMASAFLIFTIIIMFIAGTGKSGLGEKG
+TVDAFVNGASSLVGVSLIIGLARGINLVLNEGMISDTILHFSSSLVQHMSGPLFIIVLLF
+IFFCLGFIVPSSSGLAVLSMPIFAPLADTVGIPRFVIVTTYQFGQYAMLFLAPTGLVMAT
+LQMLNMRYSHWFRFVWPVVAFVLIFGGGVLITQVLIYS*
+>abc_00010
+MTHLTKVLDTLTGICVVLLFSKYFVAYANMVFDWNLRWYLLENIPHLPIILFILMFIFGV
+PSEMIKDRQRKNNGV*
+>abc_00011
+MRLQKAPLVTSGLVLGLLGLGNLLKDLSLTLNAVCGIFAFLIWIHLLCTMIKYFNNVKEQ
+LNSPLVSSVFTTFFMSGFLGTTYLNTFFSNITFINSLITPIWILCLVGIMTHMIIFSIKY
+LKDFSLENVYPSWTVLFIGIAIAGLTAPVSGCFFIGQLTVIYGFVATCIVLPIVFKRLKA
+FPLQTSIKPNTSTICAPFSLVAAAYVIAFPKANAFIVIIFLILAQIFYFYIIIQLPKLLK
+EPFSPVFSAFTFPLVISATALKNSLPVLMFPDIWKGLLFIEVLLATVIVLRVFIGYLHFF
+LKKENQDKFLRNASQ*
+>abc_00012
+MRNQIQKLLDSDLSSLHISKQTGVPQSTIHRMRKKERSLDNMSLKNAELLYKFANSIFSN
+EN*
+>abc_00014
+MEGLFNAIKDTVTAAINNDGAKLGTSIVSIVENGVGLLGKLFGF*
+>abc_00015
+MTGLAEAIANTVQAAQQHDSVKLGTSIVDIVANGVGLLGKLFGF*
+>abc_00016
+LGYKNILIDFDDTIVDFYDAEEWAFHYMANVFNHKATKDDFLTFKKINHQHWEAFQQNKL
+TKSEVLSERFVNYFKHHQMEVDGHRADVLFRNGLAEAKVKYFDQTLETIVELSKRHDLYI
+VTNGVTETQKRRLNQTPLHKYIKKIFISEETGYQKPNPEFFNYVFNDIGEDERQHSIIVG
+DSLTSDILGGINAGIATCWFNFRGFDHNPGIIPDYEINSWKQLNDIVR*
diff --git a/t/data/example_annotation_2.gff b/t/data/example_annotation_2.gff
new file mode 100644
index 0000000..ce5e1bd
--- /dev/null
+++ b/t/data/example_annotation_2.gff
@@ -0,0 +1,271 @@
+##gff-version 3
+##sequence-region abc|SC|contig000001 1 15000
+abc|SC|contig000001 Prodigal:2.60 CDS 172 1131 . - 0 ID=abc_00001;gene=hly;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:Q2G1X0,protein motif:TIGRFAMs:TIGR01002,protein motif:Pfam:PF07968.6;locus_tag=abc_00001;product=Alpha-toxin,beta-channel forming cytolysin,Leukocidin/Hemolysin toxin family protein;protein_id=gnl|SC|abc_00001
+abc|SC|contig000001 Prodigal:2.60 CDS 1804 1950 . + 0 ID=abc_00002;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00002;product=hypothetical protein;protein_id=gnl|SC|abc_00002
+abc|SC|contig000001 Prodigal:2.60 CDS 1934 2131 . + 0 ID=abc_00003;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00003;product=hypothetical protein;protein_id=gnl|SC|abc_00003
+abc|SC|contig000001 Prodigal:2.60 CDS 2621 3337 . - 0 ID=abc_00004;inference=ab initio prediction:Prodigal:2.60,protein motif:CLUSTERS:PRK13350,protein motif:Pfam:PF02876.11;locus_tag=abc_00004;product=superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00004
+abc|SC|contig000001 Prodigal:2.60 CDS 3445 4170 . - 0 ID=abc_00005;gene=speH;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P0C0I6,protein motif:CLUSTERS:PRK13349,protein motif:Pfam:PF02876.11;locus_tag=abc_00005;note=SPE H;product=hypothetical protein,superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00005
+abc|SC|contig000001 Prodigal:2.60 CDS 4265 4990 . - 0 ID=abc_00006;inference=ab initio prediction:Prodigal:2.60,protein motif:CLUSTERS:PRK13043,protein motif:Pfam:PF02876.11;locus_tag=abc_00006;product=superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00006
+abc|SC|contig000001 Prodigal:2.60 CDS 5428 6429 . + 0 ID=abc_00007;eC_number=2.1.3.3;gene=argF;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P99073,protein motif:CLUSTERS:PRK04284,protein motif:Cdd:COG0078,protein motif:TIGRFAMs:TIGR00658,protein motif:Pfam:PF00185.1;locus_tag=abc_00007;product=Ornithine carbamoyltransferase,ornithine carbamoyltransferase,Ornithine carbamoyltransferase,ornithine carbamoyltransferase,Aspartate/ornithine carbamoyltransferase [...]
+abc|SC|contig000001 Prodigal:2.60 CDS 6449 7384 . + 0 ID=abc_00008;eC_number=2.7.2.2;gene=arcC1;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:Q7A627,protein motif:CLUSTERS:PRK12353,protein motif:TIGRFAMs:TIGR00746,protein motif:Pfam:PF00696.22;locus_tag=abc_00008;product=Carbamate kinase 1,putative amino acid kinase,carbamate kinase,Amino acid kinase family protein;protein_id=gnl|SC|abc_00008
+abc|SC|contig000001 RNAmmer:1.2 rRNA 7556 9112 . + 0 ID=abc_01705;inference=COORDINATES:profile:RNAmmer:1.2;locus_tag=abc_01705;product=16S ribosomal RNA
+abc|SC|contig000001 Prodigal:2.60 CDS 9419 9646 . + 0 ID=abc_00010;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00010;product=hypothetical protein;protein_id=gnl|SC|abc_00010
+abc|SC|contig000001 Prodigal:2.60 CDS 9952 10899 . - 0 ID=abc_00011;inference=ab initio prediction:Prodigal:2.60,protein motif:Pfam:PF03595.11;locus_tag=abc_00011;product=C4-dicarboxylate transporter/malic acid transport protein;protein_id=gnl|SC|abc_00011
+abc|SC|contig000001 Prodigal:2.60 CDS 11148 11336 . + 0 ID=abc_00012;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00012;product=hypothetical protein;protein_id=gnl|SC|abc_00012
+abc|SC|contig000001 Aragorn:1.2.34 tRNA 11803 11878 . - 0 ID=abc_00013;inference=COORDINATES:profile:Aragorn:1.2.34;locus_tag=abc_00013;product=tRNA-Arg(tct)
+abc|SC|contig000001 Prodigal:2.60 CDS 12241 12375 . + 0 ID=abc_00014;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P11699,protein motif:Pfam:PF05480.5;locus_tag=abc_00014;product=Gonococcal growth inhibitor III,Staphylococcus haemolytic protein;protein_id=gnl|SC|abc_00014
+abc|SC|contig000001 Prodigal:2.60 CDS 12432 12566 . + 0 ID=abc_00015;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P11699,protein motif:Pfam:PF05480.5;locus_tag=abc_00015;product=Gonococcal growth inhibitor III,Staphylococcus haemolytic protein;protein_id=gnl|SC|abc_00015
+abc|SC|contig000001 Prodigal:2.60 CDS 12699 13385 . + 0 ID=abc_00016;eC_number=3.-.-.-;gene=yfnB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:O06480,protein motif:CLUSTERS:PRK09449,protein motif:TIGRFAMs:TIGR02254,protein motif:Pfam:PF00702.1;locus_tag=abc_00016;product=Putative HAD-hydrolase yfnB,dUMP phosphatase,HAD hydrolase,haloacid dehalogenase-like hydrolase;protein_id=gnl|SC|abc_00016
+##FASTA
+>abc|SC|contig000001
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
+ATACCCACCACATTTGGTGGAGAACCAAAAATTAGCCGAAAAACATCATTTCTGAAGTTA
+TCGGCTAAAGTTATAAATTATATTTATTTGTACATGAACAAATAATTTACATTAATTTGT
+CATTTCTTCTTTTTCCCAATCGATTTTATATCTTTCTGAAGAACGATCTGTCCATTTATC
+TTTAGTATTGGTACCTTTCCAATTTGTTGAAGTCCAATGCAATTGGTAGTCATCACGAAC
+TCGTTCGTATATTACATCTATATTTGTTTGTTGTTTGGATGCTTTTCTATCCATAGTAAT
+AACTGTAGCGAAGTCTGGTGAAAACCCTGAAGATAATAGAGAACTTGCTTTGTTAGGATC
+AAGGAAGTTCTCTGCTGCTTTCATAGAACCATTTCTAGTTTTCATGAAAAGTTGATTGCC
+ATATACCGGGTTCCAAGAATCTCTATCATATGGTCCCCAATTTTGATTCACCATATTGTT
+AAATATCACTTTCCAGCCTACTTTTTTATCAGTTGGGCTCTCTAAAATTGTTTTGAAATC
+AGGTTGAACATATTTCAGTGTATGACCAATCGAAACATTTGCACCAATAAGGCCGCCAAT
+TTTTCCTGTATCATCACCAGTAACATTACCGTTGAATCCATAAGTTAAAGTACTCATATA
+CTCTTTTGTATCAATCGAATTTCTTGGATAGTAATCAGATATTTGAGCTACTTCATTATC
+AGGTAGTTGCAACTGTACCTTAAAGGCTGAAGGCCAGGCTAAACCACTTTTGTTAGCACC
+TTCTTCGCTATAAACTCTATATTGACCAGCAATGGTACCTTTCGTTCTAATAACTAGCAG
+TTTTTTATTGTGATTTTTATCATCGATAAAACTATAAAATACTTTTTTGTGCATGCCATT
+TTCTTTATCATAAGTGACTAAATCACCTGTTTTTACTGTAGTATTGCTTCCAATATCTGT
+AGTACCGGTTTTAATATTAATATCAGAATCTGCGGCATTAGCGACAGGATTCATTAATAT
+GGAACCTAGCAATAGTGTTGTTGTTACTGAGCTGACTATACGTGTTTTCATTTTCATCAT
+CCTTCTATTTTTTTTAACGATTTGAGGAAACAATAATCAATATGTCAATTTAGAATATTG
+CAGTTGAGACATATCAAATATTTATAATCGTTTATATTAGTATATTTAATGTAGCAACTG
+ATAAATTACTGAGTGATGATGAGTGATTATTTTAAGAATATGTTTTTAACTTTTATTTAA
+AATTTGAAAGGAAGCATTTCAATTTCGAGGGTTAGTCAAAGTTGAATAAATTCTTTATGA
+AACAAGGAAAAGACATAGCTAATTTTATTGATTAATTTCTTTAAAACTAATGATTTGTTT
+GATTTAAAAATGTAATCGATTACAATATAAAAATACAAATATCTTAGAATTAAATCAATT
+AATTAACTATTAAATAAAAATTAAATATATATTAACTACTGTAAATTAATAAATAGAAAT
+AGAGAAAAAGGGTATTAATTATGTTTGGAATTTCGTCGGGAATAATTTTTGCCATTACAT
+AGAAATATCTAATAGATAATGAAAAAGTATCGTATGTATTTTTAATATAGTGTAAAATAT
+CATATGTAAAATAAAATGTAGATTTTTAGTTAGAGGCATTATAAGAAAATTTTGAGTATA
+GGTTAGCTTTTAATTATGAATCTTATTGAAATTTGATTAATAAATATATGATAGGGGATT
+AAAATGAAACTATTTTATATCGTATTTCTTATTATTATATGGCTGAATATATTTTTAGGA
+AATGAAATTATCCATACACTGACTGTTTTAATAACAACATTGTATATTGTTAATTCAAGA
+AAGGGGATTAAAAATGACAGAGTTGAATAATATTATAAACTCTCTTCAATCTTTGTTTGA
+GTCTGAATCAGGCTATAAAATTTCGAAAAATTCAGGAGTTCCATATCAAACAGTACAAGA
+TTTAAGAAATGGGAAAACCAAACTAGAAGATGCTAGATTTAGAACGATTATTAAACTTTA
+TAGTTACTATGTCTCATTAAAAGAACATTAATCATGGGACAATAAAGTATTGCTATAATA
+ATTGAATCATTAAATGAAGGAATAGAGCCTAAGACATAATAAATCAATGTCTTAGGCTCT
+ACAATATTATATTGGTAGTAGTTGACCGAATGAAAATGACCATGTAACAAGCATTTTTGG
+GGCCCCAACACAGAAGCTGACGAAAAGTCAGCTTACAATAATGTGCAAGTTGGGGATGGG
+CCCCAACACAGAGAATTTCAAAAAGAAATTCTACAGACAATGCAAGTTGGCGGGGCCCCA
+ACATAGAGAAATTCAAAAAGAAATTCTACAGACAATGCAAGTTGGGGAGTGACAACGAAA
+TAAATTTTATAAAATACCATTTCTGTCACATTCCTACTCCCAATTCCATTTAAATATATA
+GAAAATTTCACCTATTATATACATCATACACTTTAAAAATTATCATTTAAATAATCTGAT
+TTGGAATTAAAGTGCATGAAGTATAAGTCACCTTCATATACTAATCAAAGAGGACGTCAA
+CAGTTATTTTATTAGGATTTTTAACATAAACATTTGCTAGATCTGAATGTAATCTTTTGC
+TTAAATCAATAGTGTAGTTATTACCGCCACCGGTGATCTTAAGCTTACCTTTATTACGAT
+TTTCGGTATATAATATTTTATTTTTTATTAACGCTTCTCGTGCACGGAAATCGATTTCTT
+TCAATGTTAATACTGGTTTATTGCCTTGGTATATTTTATGCGCACCAATAATCGTTTGTA
+GTTTATCTTTGTATTGCACAAAAAGATTATAAGTTTTATCAGAAGGTTTTGCGGCTGGTG
+TAACGCCACCTGTAAATGTCTCTCTATAAGACCACCATAACTGATCAGTATCTTTGTCTT
+TTAGTCCAAACACATCTACGTAACGATCTTTTAACTGATTAATATTTCCCCAACTTTCAG
+CGCCCCATAAAGATATATGTGCTGACCATGAATATCTCTTAAGTTCAACATAAATGTTTC
+CATTATCATATTGATATAGCCATTTATTTGAAAATGAAAAATGAGGCTGTGTGTAATATT
+TAATTAATTCATTGATGTTAGTTTCATCTTGACCAATGCTATAAGCTTTAGCTTCAGAGT
+AAAAACTAAATACTGGTTTTTGATTTTGAGGTAATACAGTACCTAATAGTAATAATGTTG
+TCGTTAAAATTATATTTTTCGTGATGTTCTTACTCATTAGAACATCTCCTTTCAGAGGAA
+TCATGATACGAGGAATAAGAAATTTAAATGTGAGCGAAGTCAATATAGTATTTGCGATTA
+TTTTTATTAACTCCATTATTATTGTTAGTTTGATTTTTCGAGGATAACTTCAATTTTTGC
+ATTTTGAGGTTTTTTAACATATCTATTTGCATCAGTTGATGGCAACCTTTTACTTAAATC
+TATTGTGTAGTTATTGTCTGTACCTGTTATTTTAATTTGTCCTTTATTATAAGAATTATT
+ATATAATTTTTTACTTTTAATTAATGTTTGACGAATACGAAAATCTAATTCTTTTAAAGT
+TAAAACAGGCTTATTGCCTTCATAAACTGGAAATCCGCCAGTAAACGTTTCTGCTTTATC
+TTTATATGTTACATTCAGTTTATAGTGTTTATCGTTAGATGTTGCTGCAGGAGTAACACC
+ACCAGTAAACGTTTCTTGAGATAATGCAAAAGAATCAATGGTTTCTTGGTCTTTTATGCC
+AAAAATATCAACGCTTTTATTTCTTAATTGGTTGATATTGCCCCAACTTTCAGGTCCATA
+AACTTGAATATGACTATACCAAGAAAACTGTAACAACGTTGCATGAATCGTACCGTTATC
+TTTTTGCCATAACGTACTGTTAGAGAAGGTTAAATATTTTTGCGAGTAATATTTAGTTAA
+CTCATTAACGTTAGTTTCGTTTTGATTTATATAATAAGCTTTCGCTTCAGATGAAGAATT
+GATAGGTGTATTAGGAAATTGTGTAAATGCTGTACCTAATAGTAACAATGTTGTTGATAA
+AATAATTTTTTTCGTGATGTTATTGTTCATTCGAATTTCTCCTTTGAGTATTGTTGGAAT
+GTTTAATTATAAAAAGGGGTTAATTAGATAATTGAAATTATCCGCATTTACAAAAGGTAA
+TAGGTTAGTTAGATTTTTCGAGTATGACTTCAATTTGTGCATTTTTAGGATTTTTAACAT
+AACGGTTTGTGTCAGTTAATTTTAACTTTTTACTTAAATCAATCGTGTAATTATTTCCAT
+CAGCAGTTATCTTAATTTGACCTTTATTAAATTCTCCGTTATATAACTTTTTATTCTTTA
+TTAATGTTTGACGAATACGGAAATCTAATTCTTTTAAAGTTAATACTGGTTTATTTCCTT
+TGTAAAATTCATGTCCACCGATGATAGTTTGTTGTTTATCACTATATTTTAAAAATAGTC
+TATAAGGTTTATCAGATGAAGTAGCTGCTGGCGTAACACCACCAGTAAATGTTTCATCAT
+AAGTCCAGTAACCTTCAACTGTGTCCTCATCTTTAGTTCCAAATATATCAACGTATTTAT
+TTCTTAACTGATTAATGTTTCCCCAACTCTCGGATCCAAACACTTGAATATGACTATACC
+AAACCCACGTTTGCAATGTTGCATGAATGCTACCATTGGGCTTTTGCCATAGCCATTTTC
+CAGATAATGAAAAATGCGGCTGAGTGTAATATTTGATTAACTCATTGATATTAGTCTCGT
+TTTCACTGATATTATAGGCTTTTGCTTCAGATGAAAAACTGATTGGTGTTTTAGGAAGTT
+GTGTTGATGTGGTTCCTAAAAGTAACAATGCTGTTGATAAAACTAATTTATTCATGATGT
+TCTTTTTCATATGAAAATCTCCTTTGCGTGAATTACCCAAAGTATATAAGCTATTACACC
+GATTCGGAATTAAATAAAAGCTAAAACTATGTTAAATAAACTTAAACAGTTAGTAGTGTT
+ATTTAAGCAAAACTTATCATTTTTAAGTTTTGGACAGAAACAGTACTTAATAAAGTAGGC
+GGGAGTTATATATTAAAAACGACACGTTACAATTATTCTCTAATCAATTGCATTAAATTG
+TTTGATAATTGAATTTTCTAACTACTTGAAAAATAGTTATACTTTAAATGTAGTACTTAT
+TTTAATTATTTCCTACTACTTAAATTTAATATTAATAAAATGTTCATTTAATTATTGATA
+AAATATTACAAATTTTAATAGTAGGTTGTGTTTATTTTGTATGCGCTTACAATTTAGGTG
+TAACTAAAATAAAAGGAGTTGTTATTAATGAAAAATTTACGAAACAGAAGTTTTTTAACT
+TTATTAGACTTTTCACGACAAGAGGTAGAATTCTTATTAACACTCTCCGAGGATTTAAAA
+CGTGCTAAATATATTGGCACTGAAAAGCCTATGTTAAAAAATAAAAATATTGCACTGTTA
+TTTGAAAAAGATTCTACAAGAACGCGATGTGCATTTGAAGTTGCAGCGCATGATCAAGGT
+GCAAATGTAACTTATTTAGGCCCAACTGGATCACAAATGGGTAAAAAAGAAACAACTAAA
+GATACTGCACGTGTGCTTGGTGGAATGTATGATGGCATTGAATACCGTGGTTTTTCACAA
+AGAACAGTAGAAACTTTAGCTGAAAATTCAGGCGTACCAGTGTGGAATGGTTTAACTGAT
+GAAGATCATCCTACTCAAGTTCTTGCTGATTTCTTAACAGCAAAAGAAGTCTTAAAAAAA
+GATTATGCAGATATTAACTTTACATATGTTGGAGATGGTCGTAATAACGTTGCAAATGCA
+TTAATGCAAGGTGCTGCCATTATGGGTATGAACTTCCATTTAGTTTGTCCAAAAGAATTA
+AATCCAACAGATGAATTATTAAATCGCTGTAAAAATATTGCCGCTGAAAATGGTGGCAAC
+ATATTAATCACAGATGATATTGACCAAGGTGTAAAAGGTTCGGATGTAATTTACACTGAT
+GTTTGGGTATCAATGGGTGAACCTGATGAAGTATGGAAAGAACGACTTGAATTATTGAAA
+CCATATCAAGTAAATAAAGAAATGATGGATAAAACTGGTAATCCAAATGTTATTTTTGAG
+CATTGCTTACCATCTTTCCATAATGCTGATACGAAAATTGGTCAACAAATTTTTGAAAAA
+TATGGTATTCGAGAAATGGAAGTTACAGATGAAGTATTCGAAAGTAAAGCTTCAGTTGTA
+TTCCAAGAAGCTGAGAACAGAATGCATACAATCAAAGCAGTCATGGTTGCTACATTGGGT
+GAATTTTAAATGATATAAGGAAGTGAATATGATGGCGAAAATAGTAGTAGCATTAGGTGG
+TAATGCTTTAGGAAAATCACCTCAAGAACAACTCGAGCTTGTTAAAAATACTGCGAAATC
+ATTAGTAGGATTAATAACAAAAGGACATGAGATTGTTATTAGTCATGGTAATGGACCACA
+GGTTGGAAGCATTAATTTGGGACTTAACTATGCTGCAGAACATAACCAAGGTCCGGCATT
+TCCATTTGCTGAATGTGGCGCAATGAGTCAAGCTTACATCGGCTATCAATTACAAGAAAG
+CTTACAAAATGAATTGCATTCTATTGGAATGGATAAACAAGTGGTAACACTAGTGACACA
+AGTTGAAGTTGATGAAAATGATCCGGCATTTAACAATCCTTCAAAACCAATTGGGTTATT
+TTACAACAAAGAAGAAGCTGAACAAATTCAAAAAGAAAAAGGATTTATATTTGTTGAAGA
+TGCTGGAAGAGGATATAGACGCGTTGTTCCTTCACCACAACCCATCTCTATTATTGAATT
+AGAGAGTATTAAAACACTTATTAAAAATGATACACTCGTTATTGCTGCTGGTGGTGGAGG
+TATACCAGTAATTAGAGAGCAACATGATGGTTTTAAAGGTATTGATGCAGTTATAGACAA
+AGATAAAACAAGTGCGTTGTTGGGTGCTAATATTCAATGCGATCAATTGATTATTTTAAC
+AGCAATTGATTATGTATATATTAATTTTAACACTGAAAACCAACAGCCTTTGAAAACAAC
+AAATGTTGATGAATTAAAACGATATATAGACGAAAATCAATTTGCAAAAGGAAGTATGTT
+ACCAAAAATTGAAGCAGCCATATCATTTATTGAAAACAATCCAAAAGGAAGTGTGCTTAT
+AACATCATTAAATGAATTAGATGCTGCCTTAGAGGGTAAAGTAGGTACTGTGATTAAAAA
+GTAATTGAATTGAAACGCTTTTCAATTACTATATGTCAAATGCATGATTTTTATTATTTA
+TGTGCACCCCCTGAAAATAATGCCTCTATTTTGATGCGGGGTGCACTTTCTTAATTTATA
+TTTATAAAATCTTTAAGGTAGAAATGCTAGGTTAAATGTCGAAGGAGATGAAACCGTGGA
+AAATACAATTAATGAAAGTGAAAAGAAAAAACGATTTAAATTAAAAATGCCAGGTGCATT
+TATGATTTTATTCATTTTAACGGTTGTTGCAGTTATAGCAACATGGGTTATTCCTGCTGG
+TGCATATTCTAAACTTTCTTACGAACCTTCATCCCAAGAACTAAAGATAGTTAACCCTCA
+TAACCAAGTGAAAAAGGTTCCGGGTACGCAACAGGAACTAGACAAAATGGGGGTTAAAAT
+TAAGATTGAACAATTTAAATCAGGTGCAATTAATAAGCCAGTATCAATTCCGAATACTTA
+TGAAAGATTAAAGCAACATCCAGCTGGACCAGAACAAATAACAAGTAGCATGGTTGAAGG
+TACGATAGAAGCGGTCGATATCATGGTATTCATTCTTGTACTAGGGGGACTTATTGGCGT
+AGTTCAAGCCAGTGGTTCTTTTGAATCGGGATTGTTAGCTTTAACGAAGAAAACAAAAGG
+GCATGAATTTATGCTAATTGTGTTTGTATCAATACTAATGATTATCGGCGGGACGTTATG
+TGGTATTGAAGAAGAAGCTGTAGCATTCTATCCGATTTTAGTCCCTATATTTATAGCGTT
+AGGATACGATTCTATCGTTTCAGTTGGTGCCATATTCCTTGCCAGCTCTGTCGGTAGTAC
+ATTTTCAACTATTAACCCGTTCTCGGTTGTAATTGCCTCTAATGCCGCTGGTACAACTTT
+TACGGATGGCTTGTATTGGAGAATAGGTGCTTGTATTGTCGGTGCGATTTTTGTTATTAG
+TTATTTATATTGGTACTGTAAAAAAATTAAAAACGATCCTAAAGCGTCATATTCTTATGA
+AGACAAAGATGCTTTTGAACAGCAATGGTCTGTATTAAAAGATGACGATAGTGCCCATTT
+TACTTTGCGTAAGAAGATAATCCTTACATTATTTGTACTACCATTTCCAATTATGGTATG
+GGGAGTTATGACGCAAGGTTGGTGGTTCCCAGTTATGGCTTCAGCATTTTTAATATTTAC
+AATTATAATAATGTTTATTGCTGGGACAGGTAAATCTGGATTGGGAGAAAAAGGAACTGT
+AGATGCATTTGTCAATGGTGCATCAAGTTTAGTAGGTGTATCTTTAATTATTGGTTTAGC
+TCGAGGTATTAATTTAGTGTTGAATGAAGGTATGATTTCAGATACAATCTTACACTTTTC
+ATCATCTTTAGTTCAACATATGAGTGGACCATTATTTATCATCGTATTACTATTTATTTT
+CTTCTGTTTAGGTTTTATCGTGCCATCATCTTCTGGATTAGCGGTATTATCAATGCCTAT
+CTTTGCACCACTAGCTGATACAGTAGGTATACCAAGATTCGTCATCGTTACGACATATCA
+ATTTGGTCAATATGCGATGTTATTCTTAGCGCCGACTGGACTTGTTATGGCCACACTACA
+AATGTTAAACATGCGATATTCACATTGGTTCCGATTTGTATGGCCGGTAGTTGCTTTTGT
+ATTGATTTTCGGTGGCGGAGTACTAATTACGCAAGTACTAATTTATTCATAATTTGAAAT
+GCTATATTATAAAAATACTAATTGGGTTTTATGCATCTCGTAGGTTTGTAGAAATACTAA
+ACTAAGCGAGGTGCATTATTATTTTTGATTAAGAAAATAATGACGGTAATGATAACACTA
+GTAAGTAATTGATACAATGCTCTATTTAATAATGATATTTTTAAAATTTGTTTTTAATGT
+AATGTTAGATCTATGGTATATTATATTTATCGTGGTAAATATGTATTTGCTGTAAACAGT
+TTTTGTAACACATGACACATATGGTTGTGAAAATAGCATATATAAAGGATGGCTATAAAT
+GACACATTTGACAAAGGTTTTAGATACACTAACTGGAATATGCGTAGTATTATTATTTAG
+TAAATATTTTGTGGCGTATGCAAATATGGTGTTTGATTGGAATTTAAGATGGTATTTGCT
+AGAAAACATACCACATTTGCCAATTATATTATTTATTCTGATGTTTATTTTCGGAGTACC
+TTCTGAAATGATAAAAGATAGGCAAAGGAAAAATAACGGTGTTTAATTTATCGATATTTA
+GAGGTGATAAAATTTGTCAACTATTACAAAGACTAAAATAAAAATCTTTATTAATTATTT
+TATTGGTATATTAGCCTTGGCGTTTGCTGCTTATATATTATTTAAATAAAGGTTAGAGTG
+AAACGTGTTTATGAACTAGACGTTCTAGTATAGTTACTACAGCTTTAGTCAGAAGGTATC
+ATTGATAAGATCATATTAAATCAAAGAGGCATTGATATACACTAAAAAGAGGCAAGATTA
+CCTGCCTCTTTTTTAGTTATTAAATATGCGTGTTAATTCTTGGTAATAGTGTTACTGAGA
+CGCATTACGAAGAAATTTATCTTGATTTTCCTTTTTTAAAAAGAAGTGAAGATATCCTAT
+AAAGACTCTAAGTACTATTACAGTGGCTAATAACACTTCGATAAACAAAAGACCTTTCCA
+AATATCTGGAAACATAAGTACAGGCAAACTGTTCTTTAAAGCAGTTGCTGAGATTACTAA
+AGGGAATGTGAAAGCTGAAAATACGGGCGAAAAAGGTTCTTTTAGTAATTTAGGCAATTG
+TATAATGATATAAAAATAAAATATTTGAGCTAATATTAAAAATATAATTACGATAAAAGC
+ATTCGCCTTAGGAAAGGCTATAACATATGCTGCAGCGACTAAAGAAAATGGTGCACAAAT
+TGTCGATGTGTTCGGTTTGATTGACGTCTGCAATGGAAATGCTTTTAATCGCTTGAAAAC
+AATAGGTAAGACAATACAAGTAGCTACAAAGCCATATATTACTGTTAATTGACCTATGAA
+AAAACATCCGCTAACGGGTGCCGTCAATCCTGCGATAGCAATACCAATAAAAAGTACAGT
+CCACGAAGGATAAACATTTTCAAGTGAAAAATCTTTTAAATATTTTATTGAAAAAATAAT
+CATATGCGTCATAATTCCCACAAGGCATAAAATCCAAATAGGCGTTATTAAGCTATTGAT
+AAAAGTTATGTTACTAAAAAATGTATTTAAATAAGTAGTACCTAAAAAGCCAGACATGAA
+AAATGTTGTGAACACTGATGAAACTAGAGGACTGTTTAATTGTTCTTTCACATTATTAAA
+ATATTTGATCATAGTACATAAAAGGTGAATCCAAATCAAGAAAGCAAAGATTCCGCAAAC
+AGCGTTTAAAGTAAGAGATAAGTCTTTTAATAGATTACCCAGGCCTAATAATCCTAAGAC
+TAGTCCTGACGTTACTAGAGGTGCTTTTTGAAGTCTCATGATTTACAACCTTTCTTATGT
+GATTTTCTTCACTAATTATATCATGATAGCTATGGCCAATTAATAAGAAGAGTGTGTACT
+ATTACGTTATTAGAGTATGTATATTGGATTGATAGACACATAATTGACATTTAAATCTCA
+AAATTAATGATATTTGAGGTATGCTTTGCAACCTAAATATTGGAATATGTGGAAAAGTAA
+TTATTTAATTTAAATGATGATTGAAGATTTACAAGGGGGTGTACAAAATGAGAAATCAAA
+TTCAAAAACTATTAGACAGTGATTTGAGCAGTTTACATATATCGAAACAAACAGGAGTTC
+CACAAAGCACAATACACAGAATGAGAAAAAAAGAAAGATCATTAGACAATATGTCATTGA
+AAAACGCTGAACTACTTTATAAATTTGCCAATAGTATATTTAGCAATGAAAATTAAGAAG
+AATAATTAGTGAGTTAAATAATTAAAAAACCACGTCTCGATGGACGTGGTTATTTTTTTA
+AATGTATTTAATTATAGGATTTCGGGCCCCTGAAAAGTCCCTAAAATTTTGAATAGTATC
+AAAATCTATAGGAATAATATAATAATAAAAATCTCTACGCATGCAAATGGTGAGTGTTAA
+AAATCTTGGTGTAGTGTTGGTGTAGTTCAGGTGCAGTATAGATGAAATTTGAGCACAAAA
+TTACTTAATTAAAAATGTATAAACAAGTGTCAGACGCGTGTCAATTGTGTGTCAAAAAAT
+TCTATGACGAATAAGCATGCTTGTTTTAATTACTGTATTTTCGGGGCTTATGCGGGGGAC
+GTTTTGGTGACGCATCATACTATATTACTGAAATTCAAAACAAAAAGAGCCCCGTAATCA
+CGGAACTCTTTTGTTTGGTAATGCGTATAAAAATACCTATAAACGTCCTGGGAGGGATTC
+GAACCCCCGACCGATGGCTTAGAAGGCCATTGCTCTATCCAGCTGAGCTACCAGGACACG
+TTTAACAACACAAGAATTATTATATCTAAATGAACTTAAATTAGCAATACCTTGTAAATA
+AAAAATGTTTATATTTTTCACTATTATAGAGCTATTTATCTAAAAAGGTTCAATAAGACT
+TAAATGCGAATTCAGGCAACTTAATTGTGTTAAATACAGTTTTGAATGCCTAACTGTATT
+TCTTTTCTCTTTAAAATACAGTTAAGTACATTATAAGATGTTGTGCGGATAAACAAACTA
+ATTGCATCAAATTTATTTTAAAATAACAACAACAAAACGTTAAGCGAATAACATTTCGGT
+GATTTAAAAGCTACGCACGTTTTTGTTATCTTCAAATTTAAATTTTAAGGAGTGTTTTCA
+ATGGAAGGTTTATTTAACGCAATTAAAGATACCGTAACTGCAGCAATTAATAATGATGGC
+GCAAAATTAGGCACAAGCATTGTGAGCATCGTTGAAAATGGCGTAGGTTTATTAGGTAAA
+TTATTCGGATTCTAATTTCAATATGTTATGTAAGTAATCAGTATTATTTCAAAGGTGAGG
+GAGAGATTTAAATGACTGGACTAGCAGAAGCAATCGCAAATACTGTGCAAGCTGCACAAC
+AACATGATAGTGTGAAATTAGGCACAAGTATCGTAGACATCGTTGCTAACGGTGTGGGTT
+TACTAGGTAAATTATTTGGATTCTAATATAATAACTAATATTCTTTAAAATAAACTGGGT
+GAGCATACTTTAATGTTATGCACTCAGTTTATTTTATTTGCAGAAATTTGAGCCTCTGTT
+AAGATTTAGATACATAGACAATATAGGAGATGGGGAAATTGGGATATAAAAATATTTTGA
+TAGACTTTGATGATACAATTGTTGATTTTTATGATGCAGAAGAATGGGCGTTTCACTATA
+TGGCGAATGTTTTTAATCATAAAGCAACAAAGGATGATTTTTTAACATTTAAAAAAATCA
+ATCACCAACATTGGGAAGCTTTTCAACAAAATAAATTAACGAAGTCTGAAGTATTATCAG
+AACGATTTGTGAATTACTTCAAACATCATCAAATGGAAGTTGATGGGCATCGTGCAGATG
+TGTTATTTAGAAATGGATTAGCAGAAGCTAAAGTTAAATACTTTGATCAAACATTAGAAA
+CAATTGTCGAATTATCGAAAAGACATGATTTATATATTGTTACTAATGGTGTAACCGAAA
+CGCAAAAGAGAAGGTTAAATCAGACGCCGTTGCATAAATATATTAAAAAGATATTTATAT
+CTGAGGAAACAGGATATCAAAAACCTAATCCGGAATTTTTTAATTATGTTTTTAATGATA
+TTGGTGAGGATGAAAGACAGCACTCGATTATAGTTGGAGATTCTTTAACATCTGACATTC
+TAGGTGGAATCAATGCGGGTATAGCTACTTGCTGGTTTAATTTTAGAGGATTTGATCATA
+ATCCAGGAATTATACCTGATTATGAAATTAATTCATGGAAACAACTAAATGATATTGTAC
+GTTAAGACAAATAATTTGAAAATGATTTATATTAGCTTAAGAAAGTAATTGTAAAAACGA
+CACTACGAAAAGATGCATTTTCATGCTCGTAGTGTCGAATATTATTATCTTATGGTTTCC
+ACAATAAGACATCATGTCCCTCTATATTTTTAGCTTCCACATCTGTAAATCCATGATGTA
+AAAAGAAATCCTTAGAATCATTTCTGCCAATGGCTTTAATTGGCATATTGAAACTCTTTG
+CAAAATCAATCAATTCTGAAGCGTACCCTCTGTTTTGATATTTTGGTAATACTTCTAACT
+TCCATAATAATATATAATCTTCAAAATCTGGGAAGTAGATTTCTTCGACATCACCTTTTT
+TTAGTAATGCCATTCTAGCTCCTAATTGATCTCCGACAAATATGCCATAAAATGGTGAAT
+CTGAACTTGCATCAATCATTTGACCGTTTAACTCATTGACCATGTATAAGTCTTTGTTGC
+CAAACGCTCTAAAGTTTTCGAATAATTCGTCAGTTTTGTAATTAATTTCAAGACGTTTGA
+TTTCACTCATATTTATCTACCCCTTATTTGTTTACTACTATTATTATACATTAAACCACT
+TGTGTTTTTCATTGATTTGAAAATGTAAAACAATGAACATTATAAATTTTCCATGATTAA
+ATTGATTTTCAAGCCGTAAAATTGTCAATCACCGGTATAGACTTTATACTATAGTTTGTA
+ATCGCGTACTTAAGGAGAAAAAACATGGACTGTAAAGTAGTTAGTTTAAATGAAAAAGAT
+CAGTTTATACCAAAAATAAAGAGCAGTGACCCTGTAATAACAGGATTATTTCAATATGAT
+GCAGCTCAACAAACTAGTTTTGAAAAAAGGATGTCTAAAGAAAATAATGGAAGAGAAGCG
+GCATTAGCGAATGTTATTCGTGAATATATGAGTGATTTAAAGCTTTCAAATGAACAAGAA
+TTAAACATACAACATTTAGCTAATGGTTCAAAAGTTGTGATTGGTGGACAACAAGCAGGG
+CTTTTCGGGGGACCATTGTATACATTCCATAAAATATTTTCAATCATTACTTTATCTAAG
+GAATTAACGGATACACATAAGCAACAAGTAGTACCAGTTTTTTGGATTGCAGGAGAAGAT
+CATGATTTCGATGAAGTGAATCATACATTTGTTTATAACGAAAATCATGGGTCGCTGCAT
+AAGGTTAAATATCATACAATGGAGATGCCAGAGACGACAGTCTCTAGATATTATCCTGAT
+AAGGCTGAGTTGAAACAAACTTTAAAAACGATGTTCATTCATATGAAAGAAACTGTTCAT
+ACACAAGGTCTACTGGAGATTTGTGACAGAATTATTGACCAATATGACTCGTGGACTGAT
+ATGTTTAAAGCACTACTGCATGAAACATTTAAAGCATATGGCGTTCTATTTATAGATGCG
+CAGTTTGAGCCGTTAAGAAAAATGGAAGCGCCTATGTTTAAAAAGATTTTGAAAAAACAT
+CAGTTGCTTGATGATGCTTTTAGAGCAACACAACAACGTACTCAAAATCAAGGCTTGAAT
+GCGATGATACAAACAGATACAAATGTTCATTTATTCTTACATGATGAAAATATGCGCCAA
+TTAGTTTCGTATGATGGTAAGCATTTTAAATTAAATAAAACAGATAAGACATATATAAAG
\ No newline at end of file
diff --git a/t/data/example_groups b/t/data/example_groups
new file mode 100644
index 0000000..adbc922
--- /dev/null
+++ b/t/data/example_groups
@@ -0,0 +1,6 @@
+group_1: 1234#10_00001 1234#10_00002
+group_2: 1234#10_00003 1234#10_00018 1234#10_00005
+group_3: 1234#10_00005 1234#10_00005
+group_4: 1234#10_00006 1234#10_00007
+group_5: 1234#10_00016
+group_6: 1234#10_00017
\ No newline at end of file
diff --git a/t/data/example_groups_without_labels b/t/data/example_groups_without_labels
new file mode 100644
index 0000000..2c56a9a
--- /dev/null
+++ b/t/data/example_groups_without_labels
@@ -0,0 +1,6 @@
+1234#10_00001 1234#10_00002
+1234#10_00003 1234#10_00018 1234#10_00005
+1234#10_00005 1234#10_00005
+1234#10_00006 1234#10_00007
+1234#10_00016
+1234#10_00017
\ No newline at end of file
diff --git a/t/data/exp_qc_report.csv b/t/data/exp_qc_report.csv
new file mode 100644
index 0000000..83477e5
--- /dev/null
+++ b/t/data/exp_qc_report.csv
@@ -0,0 +1,4 @@
+Sample,Genus,Species
+assembly1,Clostridium,Clostridium difficile
+assembly2,Escherichia,Escherichia coli
+assembly3,Streptococcus,Streptococcus pneumoniae
diff --git a/t/data/exp_qc_report_real.csv b/t/data/exp_qc_report_real.csv
new file mode 100644
index 0000000..3d18a94
--- /dev/null
+++ b/t/data/exp_qc_report_real.csv
@@ -0,0 +1,3 @@
+Sample,Genus,Species
+query_1,Staphylococcus,Staphylococcus aureus
+query_2,Staphylococcus,Staphylococcus aureus
diff --git a/t/data/expected_0.seq b/t/data/expected_0.seq
new file mode 100644
index 0000000..fcf59dd
--- /dev/null
+++ b/t/data/expected_0.seq
@@ -0,0 +1,4 @@
+>1234#10_00001 nudix hydrolase
+MSKHGFFQITQKLFLRKGDELLILRDRKSGLGDLPGGRMNENEFFEDWSLSMQREIEEEL
+GSQVQIRVSTKPLFIHKHKVNEGNFPCIIIAYHADYLGGDIILSDEHDYISWEKVQTYEP
+SPLFTEYMLDAVNLYLKEYAPLVH*
diff --git a/t/data/expected_5.seq b/t/data/expected_5.seq
new file mode 100644
index 0000000..635abbe
--- /dev/null
+++ b/t/data/expected_5.seq
@@ -0,0 +1,6 @@
+>1234#10_00007 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
+MIVIPAIDLFDNCAVRLFKGNYEEKKIYSSEPWKLAESFAKNGATLLHLVDLNGARNQLG
+VNEDSILKIRETTSLKVQLGGGIRDKEKLAYYDKIGINRFILGTAAVTNPDLLKYALDNY
+GKERVVVAVDARDGIVKIAGWEKDSGIHYRDLLERLVKAGIEHIVFTDIAQDGTLAGPNL
+EAYREILNSYPFQVIASGGIASLKDLMDLSSLKTKISLYGVITGKALYEGKLDLAKAISS
+I*
diff --git a/t/data/expected_accessory_binary_genes.fa b/t/data/expected_accessory_binary_genes.fa
new file mode 100644
index 0000000..b8b45df
--- /dev/null
+++ b/t/data/expected_accessory_binary_genes.fa
@@ -0,0 +1,8 @@
+>aaa
+AAAA
+>bbb
+CAAA
+>ccc
+CCAA
+>ddd
+CCCA
diff --git a/t/data/expected_accessory_binary_genes_bounded.fa b/t/data/expected_accessory_binary_genes_bounded.fa
new file mode 100644
index 0000000..2663ac3
--- /dev/null
+++ b/t/data/expected_accessory_binary_genes_bounded.fa
@@ -0,0 +1,8 @@
+>aaa
+AA
+>bbb
+AA
+>ccc
+CA
+>ddd
+CC
diff --git a/t/data/expected_clustered_proteins b/t/data/expected_clustered_proteins
new file mode 100644
index 0000000..6646b09
--- /dev/null
+++ b/t/data/expected_clustered_proteins
@@ -0,0 +1,9 @@
+group_5: 1234#10_00006 3333#10_00006
+group_1: 1234#10_00001 3333#10_00001
+group_6: 1234#10_00007 3333#10_00007
+group_9: 1234#10_00018 3333#10_00018
+group_3: 1234#10_00003 3333#10_00003
+group_7: 1234#10_00016 3333#10_00016
+group_4: 1234#10_00005 3333#10_00005
+group_8: 1234#10_00017
+group_2: 1234#10_00002
diff --git a/t/data/expected_clusters_to_inflate b/t/data/expected_clusters_to_inflate
new file mode 100644
index 0000000..5fc874a
--- /dev/null
+++ b/t/data/expected_clusters_to_inflate
@@ -0,0 +1,4 @@
+2363_5_03666 4075_2#3_03437
+4075_1#8_03461 2212_1_02994 2212_6_02081 2363_1_00606 2363_2_02124 2363_3_01371 2363_6_01272 2363_8_00966 2541_2_02425 2541_3_02449 2541_7_00441 2541_8_00644 2781_2_02909 3634_6_00968 3634_7_01056 3634_8_02606
+2212_3_02841 2363_5_00947
+2363_7_00085 2460_2_00826 4075_1#6_04091 4075_1#3_04238 3634_6_04078 2212_1_01414 2363_1_00811 2541_2_00696 2541_8_00920 3634_7_00911
diff --git a/t/data/expected_combined_proteome.fa b/t/data/expected_combined_proteome.fa
new file mode 100644
index 0000000..fc98fa8
--- /dev/null
+++ b/t/data/expected_combined_proteome.fa
@@ -0,0 +1,56 @@
+>1234#10_00001 nudix hydrolase
+MSKHGFFQITQKLFLRKGDELLILRDRKSGLGDLPGGRMNENEFFEDWSLSMQREIEEEL
+GSQVQIRVSTKPLFIHKHKVNEGNFPCIIIAYHADYLGGDIILSDEHDYISWEKVQTYEP
+SPLFTEYMLDAVNLYLKEYAPLVH*
+>1234#10_00002 intramembrane serine protease
+MIIKLKIILNSYLIYYFLRGQNTLIRTLLFEFPLTTFFVFLMVATFFIVNVFLPEHLIRQ
+YFLNHPGQIQPLSWIGAVFYHGNLIHLFGNMFYLFFLGRAVEYKAGKGRWLLFFFMAALI
+SSLLDSFIRGVILHDPTPVVGASGAISGIAAVAALLSPFSLRFNQRNIPFPVFLVAWIMV
+YSDITNVFTEDGVARWAHLGGFISVIFAAYFLKPTERKQLHSGFILNLIFIILTLILAFF
+YSNRS*
+>1234#10_00003 hypothetical protein
+VKTTLSGEIEKLRYEVAVKIVNLQGEVLDLRAEMKINFSEVNSKILKLQFEFEMAKIRKE
+LKTEIADLRAETKTDFLELQKSIVDIYKTISTQTRWILGVATLFAAIGKVIN*
+>1234#10_00005 imidazoleglycerol-phosphate dehydratase or histidinol-phosphatase
+LTDKLIGFYDPVRMKAERKTSETEIKLEMNLRGTGQYQFDTEIPFFEHMLSHISKHGLID
+LNLWLRGDIEIDCHHSVEDTAILMGATIHKQLGDKAGIFRYGHFTLTMDEVLTTVAVDLG
+GRYFFKYTGPELTGKFGIYDAELSLEFLQKLALNAKMNLHVVVHYGDNKHHVHESIFKAL
+GKALRMAIAQDSAAAGAIPSTKGVLE*
+>1234#10_00006 imidazole glycerol phosphate synthase subunit HisH
+MIAILDYGMGNIHSCLKAVSLYTKDFVFTKDHSTIENSKALILPGDGHFDKAMENLNSTG
+LRKTIDKHVTSGKPLFGICIGFQILFESSEEIAQGSKKEQIEGLGYIKGKIKKFHGKDFK
+VPHIGWNRLQIRRKDKSVLLKGIGDQSFFYFIHSYRPTDAEGNAITGLCDYYQEKFPAVV
+EKNNIFGTQFHPEKSHTHGLKLLENFIRFI*
+>1234#10_00007 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
+MIVIPAIDLFDNCAVRLFKGNYEEKKIYSSEPWKLAESFAKNGATLLHLVDLNGARNQLG
+VNEDSILKIRETTSLKVQLGGGIRDKEKLAYYDKIGINRFILGTAAVTNPDLLKYALDNY
+GKERVVVAVDARDGIVKIAGWEKDSGIHYRDLLERLVKAGIEHIVFTDIAQDGTLAGPNL
+EAYREILNSYPFQVIASGGIASLKDLMDLSSLKTKISLYGVITGKALYEGKLDLAKAISS
+I*
+>1234#10_00016 hypothetical protein
+MKVTHSCLEFDSIEGLIDFAREFETGSMIRFLSPIEDNSGNVLVKEEVQVKESTLARLKD
+IKGQYTPKFEVKLNKELLEQIQNILAIKIVNQLKVTDMKFLKFMYENTNYNFKGIIRNSL
+LSKKTTLTLLKVYNQNLNFFKYISELGLLSLGIVMIPDTMRFRLLRRYAFTAGILMDVPR
+IGVDKFTKLPSDDNEKVRVAHKCSDILQKLDLIEFTYGSISNHMPLGMIEDSTSSDKAAP
+GENIDETFLDDIISNDGESDSKVDGSREDAIPEKSYDIFQALLTDALKLARYIANVSHNA
+VDKDYVMEELVYYIAYNTSKKYFDELLANPLVATFKEFEVNVKRLRKIAEVEMKCVYPPS
+AWAYPKPKSSQVLCKNKVWDCPNIVMGWDIHVITAQEAFGWVGTSLPVDNYPKCRLEEEL
+DEIMVEPEKPKKK*
+>1234#10_00017 LipL45-like lipoprotein
+MKRYLSIVILCTFAMLLLVCSTNKSSGSDQVKTESNATSARIVWLLGDVKILSDSGEKKA
+ELGASLSSTDRVVTGPNGGAEIMVADSGIIKMSKNSDIEISSLMNPNGSDTNVQVNYGKI
+VTMVKKGQKTTEFTVSTPTALAGVRGTSFLTSVESPEGSKINCAKANCTVRFAVIEGTIA
+VSKKGESSEVILSKNRELRIEKNQKLTDKLIRSLQNDSLSEMKELIVLHKNETFEYGKLV
+EELKSSSEELKILSQSGSVEEVKAAFQKREADRNNADEITKTAKAVNETKYVQQDVQKEK
+LKLNPKETF*
+>1234#10_00018 putative lipoprotein
+MDFSFNLVDNNGTVMRSTFSPIRFFTFSFLWILIDCSSVQKIENFNSVLQEPTFKSLKEE
+EAILGGSSDSDYKIRKTGNTIPVFVLSPIQTPEGMDSKLAAFLSDEVRLIWAKVKGKQVR
+IQEMSWKNPSQLSQELKRLNVDAVIKTDIREVSGKWVVNQKITDPVKEIVYGSVDGSFQS
+PKIEDELQANQAYYLKHGSGVLALDAKSSLVPIWEKSLSSGEIDSILKKSIQGYLSFSAS
+SADTEVLFQGEKIGIASFRNYPLPEGLQQIQITRPGQKDISKSLQIRSGQTISIYQEWKE
+DRTLGGVRILSFPEALQVALDGLKMGETPFYRSNLTPGAMQLELVRETENGPLVYYEGQL
+IVDADKITEIALPYKTDNLISEPEFWKLSGEKGFQAFSGKTLDFQNVSSLPPGWYGVFSA
+PFVPENMELEGIIPITAESDSGIVAISFHTSKKTISLEYEKERLSVYSFPSNGNNVGTYK
+FKKEDKEDGRPFRIITDVKEGTIRLYLGYSKVLEDRLDVSGVWRISILTRGENFSKRSPL
+RNLKIEYKGYK*
diff --git a/t/data/expected_combined_proteome_with_filtering.fa b/t/data/expected_combined_proteome_with_filtering.fa
new file mode 100644
index 0000000..b037784
--- /dev/null
+++ b/t/data/expected_combined_proteome_with_filtering.fa
@@ -0,0 +1,82 @@
+>1234#10_00001 nudix hydrolase
+MSKHGFFQITQKLFLRKGDELLILRDRKSGLGDLPGGRMNENEFFEDWSLSMQREIEEEL
+GSQVQIRVSTKPLFIHKHKVNEGNFPCIIIAYHADYLGGDIILSDEHDYISWEKVQTYEP
+SPLFTEYMLDAVNLYLKEYAPLVH*
+>1234#10_00002 intramembrane serine protease
+MIIKLKIILNSYLIYYFLRGQNTLIRTLLFEFPLTTFFVFLMVATFFIVNVFLPEHLIRQ
+YFLNHPGQIQPLSWIGAVFYHGNLIHLFGNMFYLFFLGRAVEYKAGKGRWLLFFFMAALI
+SSLLDSFIRGVILHDPTPVVGASGAISGIAAVAALLSPFSLRFNQRNIPFPVFLVAWIMV
+YSDITNVFTEDGVARWAHLGGFISVIFAAYFLKPTERKQLHSGFILNLIFIILTLILAFF
+YSNRS*
+>1234#10_00003 hypothetical protein
+VKTTLSGEIEKLRYEVAVKIVNLQGEVLDLRAEMKINFSEVNSKILKLQFEFEMAKIRKE
+LKTEIADLRAETKTDFLELQKSIVDIYKTISTQTRWILGVATLFAAIGKVIN*
+>1234#10_00005 imidazoleglycerol-phosphate dehydratase or histidinol-phosphatase
+LTDKLIGFYDPVRMKAERKTSETEIKLEMNLRGTGQYQFDTEIPFFEHMLSHISKHGLID
+LNLWLRGDIEIDCHHSVEDTAILMGATIHKQLGDKAGIFRYGHFTLTMDEVLTTVAVDLG
+GRYFFKYTGPELTGKFGIYDAELSLEFLQKLALNAKMNLHVVVHYGDNKHHVHESIFKAL
+GKALRMAIAQDSAAAGAIPSTKGVLE*
+>1234#10_00006 imidazole glycerol phosphate synthase subunit HisH
+MIAILDYGMGNIHSCLKAVSLYTKDFVFTKDHSTIENSKALILPGDGHFDKAMENLNSTG
+LRKTIDKHVTSGKPLFGICIGFQILFESSEEIAQGSKKEQIEGLGYIKGKIKKFHGKDFK
+VPHIGWNRLQIRRKDKSVLLKGIGDQSFFYFIHSYRPTDAEGNAITGLCDYYQEKFPAVV
+EKNNIFGTQFHPEKSHTHGLKLLENFIRFI*
+>1234#10_00007 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
+MIVIPAIDLFDNCAVRLFKGNYEEKKIYSSEPWKLAESFAKNGATLLHLVDLNGARNQLG
+VNEDSILKIRETTSLKVQLGGGIRDKEKLAYYDKIGINRFILGTAAVTNPDLLKYALDNY
+GKERVVVAVDARDGIVKIAGWEKDSGIHYRDLLERLVKAGIEHIVFTDIAQDGTLAGPNL
+EAYREILNSYPFQVIASGGIASLKDLMDLSSLKTKISLYGVITGKALYEGKLDLAKAISS
+I*
+>1234_00186 GGDEF family protein
+MNFENEYDLEKLVNNSLDLLTIVDLSGNVLLVNPAFERTLGWKKEDLVGKDPFHLLHPED
+KESTYKEFEKLNQGLLTLSFQNRYICADGQYRYFSWTASPDLVSGLVYVTGRDITDVIES
+NRKISQLAVKLKETNDRLFEQASTDPLTKLKNRRMFNEELNNLIHACDKESHPLSLLMID
+ADHFKDYNDKFGHIAGDKVLVELASILTKTFRKKDVLARYGGEEFIAALPNTSEPEANQI
+AERLVQTVREFSWEKRSVTISVGITTYNFNPTSKSINSEYLLNLIEQADKALYCSKVSGR
+XXXXXXXXXXXXXXXXXXXYYI*
+>1234_00325 only a few unknowns so keep
+MAFDPSVPQQQAQAPAGTLLFPEGSSANTLNVLHSGTVRYLTEVPGGRKLELFKLNGANL
+TPGSVALFTSGRYPFHLQAEEACVISTYAMNRDTISKSVGSRVSLGLMVARTLLREITEL
+FKKSNQIRKITSEIEKVNDNLSILYYQFNPSVFPDIKPGSPIPEVSADVVDPVMRLCREN
+LKLFFDNGGILPDRPSPQFLEEEHESQLTRLYPEEIDFQDGEFNFIRKLVMQDPKILNVL
+FTADPSMLAYVCSKLANVLDQISGILKTCLTDLDEAFRIFFIGENSLVEKFYLILDITSS
+GYGTAPAEFVIPVLGAFAGKIEKYKNGHQALFGVPVANISPNTQAFQSKAVTLAKKMEET
+APKVQAPVTSSATAGVDVDAIRKELDNSASVIIQFSGLGAEQIKEFSALMVKVKSLKNPL
+DPEGDNRKVRRTLGRHYWDMYQECFTKYMNSNRNVPKPVELMLKYGYFDETLVDDSQIAF
+MYTQKDPANFTSNVPISLGTEWLEKVFKREVPTSLDEMGQNFFEKVKLENRNIVIKKESD
+IPPELDNPDTRLKFEFASLYEANVRLTSGSPATHFPILTKFHSQMAIDKSYVSKKILEEV
+VHELMAVDYSIFHREVIYNNNELGITKEFIQKCVIPDFILVPSIGTKVMMWQDLSIHRGA
+GSKESPGRIVLPIFAQGDLKTMVADALAAFRWELTKSILGAEWNNVGNPSITADYTDYIQ
+FFKKNKDLSMEIKEKLASDFKRFRNDRDIFANDYQLWMKYEADGVQRLNKVVRGIFYRHI
+PFSKQVRDKVAXXXXXXXXXXXXXLLPLQRSITDLLILEIENILK*
+>1234_00377 Uncharacterized protein conserved in bacteria
+MTLNEFAKNVLFGSGLEDKLFSPPVHPVDIRSFDFLNVPSLPAREKKIQISEQKSKIPRL
+EQLFNEENRIITLHHFANHELMAIELFAWAILKFQDAPSSIRFGLYRTLLEEQTHLKMYL
+SEMKKGGMELGDRPLNFIFWKQVPKMQTLEKFXXXXXXXXXXXXXXXXXF*
+>1234#10_00016 hypothetical protein
+MKVTHSCLEFDSIEGLIDFAREFETGSMIRFLSPIEDNSGNVLVKEEVQVKESTLARLKD
+IKGQYTPKFEVKLNKELLEQIQNILAIKIVNQLKVTDMKFLKFMYENTNYNFKGIIRNSL
+LSKKTTLTLLKVYNQNLNFFKYISELGLLSLGIVMIPDTMRFRLLRRYAFTAGILMDVPR
+IGVDKFTKLPSDDNEKVRVAHKCSDILQKLDLIEFTYGSISNHMPLGMIEDSTSSDKAAP
+GENIDETFLDDIISNDGESDSKVDGSREDAIPEKSYDIFQALLTDALKLARYIANVSHNA
+VDKDYVMEELVYYIAYNTSKKYFDELLANPLVATFKEFEVNVKRLRKIAEVEMKCVYPPS
+AWAYPKPKSSQVLCKNKVWDCPNIVMGWDIHVITAQEAFGWVGTSLPVDNYPKCRLEEEL
+DEIMVEPEKPKKK*
+>1234#10_00017 LipL45-like lipoprotein
+MKRYLSIVILCTFAMLLLVCSTNKSSGSDQVKTESNATSARIVWLLGDVKILSDSGEKKA
+ELGASLSSTDRVVTGPNGGAEIMVADSGIIKMSKNSDIEISSLMNPNGSDTNVQVNYGKI
+VTMVKKGQKTTEFTVSTPTALAGVRGTSFLTSVESPEGSKINCAKANCTVRFAVIEGTIA
+VSKKGESSEVILSKNRELRIEKNQKLTDKLIRSLQNDSLSEMKELIVLHKNETFEYGKLV
+EELKSSSEELKILSQSGSVEEVKAAFQKREADRNNADEITKTAKAVNETKYVQQDVQKEK
+LKLNPKETF*
+>1234#10_00018 putative lipoprotein
+MDFSFNLVDNNGTVMRSTFSPIRFFTFSFLWILIDCSSVQKIENFNSVLQEPTFKSLKEE
+EAILGGSSDSDYKIRKTGNTIPVFVLSPIQTPEGMDSKLAAFLSDEVRLIWAKVKGKQVR
+IQEMSWKNPSQLSQELKRLNVDAVIKTDIREVSGKWVVNQKITDPVKEIVYGSVDGSFQS
+PKIEDELQANQAYYLKHGSGVLALDAKSSLVPIWEKSLSSGEIDSILKKSIQGYLSFSAS
+SADTEVLFQGEKIGIASFRNYPLPEGLQQIQITRPGQKDISKSLQIRSGQTISIYQEWKE
+DRTLGGVRILSFPEALQVALDGLKMGETPFYRSNLTPGAMQLELVRETENGPLVYYEGQL
+IVDADKITEIALPYKTDNLISEPEFWKLSGEKGFQAFSGKTLDFQNVSSLPPGWYGVFSA
+PFVPENMELEGIIPITAESDSGIVAISFHTSKKTISLEYEKERLSVYSFPSNGNNVGTYK
+FKKEDKEDGRPFRIITDVKEGTIRLYLGYSKVLEDRLDVSGVWRISILTRGENFSKRSPL
+RNLKIEYKGYK*
diff --git a/t/data/expected_complement_of_groups.gg b/t/data/expected_complement_of_groups.gg
new file mode 100644
index 0000000..5efc9be
--- /dev/null
+++ b/t/data/expected_complement_of_groups.gg
@@ -0,0 +1,6 @@
+group_3: 1_3 3_3
+group_4: 2_4 3_4
+group_2: 1_2 2_2
+group_7: 2_7
+group_5: 3_5
+group_6: 1_6
diff --git a/t/data/expected_complement_of_groups_core0.66.gg b/t/data/expected_complement_of_groups_core0.66.gg
new file mode 100644
index 0000000..0028476
--- /dev/null
+++ b/t/data/expected_complement_of_groups_core0.66.gg
@@ -0,0 +1,3 @@
+group_7: 2_7
+group_5: 3_5
+group_6: 1_6
diff --git a/t/data/expected_core_60_summary_statistics.txt b/t/data/expected_core_60_summary_statistics.txt
new file mode 100644
index 0000000..40c71d8
--- /dev/null
+++ b/t/data/expected_core_60_summary_statistics.txt
@@ -0,0 +1,5 @@
+Core genes (60% <= strains <= 100%) 75
+Soft core genes (58% <= strains < 59%) 0
+Shell genes (15% <= strains < 58%) 20
+Cloud genes (0% <= strains < 15%) 0
+Total genes (0% <= strains <= 100%) 95
diff --git a/t/data/expected_core_gene_alignment.aln b/t/data/expected_core_gene_alignment.aln
new file mode 100644
index 0000000..804067d
--- /dev/null
+++ b/t/data/expected_core_gene_alignment.aln
@@ -0,0 +1,4 @@
+>query_1
+AAAAA-GGGGGTTTTT
+>query_2
+CCCCC-TTTTTGGGGG
diff --git a/t/data/expected_core_gene_alignment_core0.66.aln b/t/data/expected_core_gene_alignment_core0.66.aln
new file mode 100644
index 0000000..e542299
--- /dev/null
+++ b/t/data/expected_core_gene_alignment_core0.66.aln
@@ -0,0 +1,6 @@
+>query_1
+TTTTT
+>query_2
+GGGGG
+>query_3
+NNNNN
diff --git a/t/data/expected_create_pan_genome.fa b/t/data/expected_create_pan_genome.fa
new file mode 100644
index 0000000..7c3efb9
--- /dev/null
+++ b/t/data/expected_create_pan_genome.fa
@@ -0,0 +1,56 @@
+>1234#10_00016 (null)
+MKVTHSCLEFDSIEGLIDFAREFETGSMIRFLSPIEDNSGNVLVKEEVQVKESTLARLKD
+IKGQYTPKFEVKLNKELLEQIQNILAIKIVNQLKVTDMKFLKFMYENTNYNFKGIIRNSL
+LSKKTTLTLLKVYNQNLNFFKYISELGLLSLGIVMIPDTMRFRLLRRYAFTAGILMDVPR
+IGVDKFTKLPSDDNEKVRVAHKCSDILQKLDLIEFTYGSISNHMPLGMIEDSTSSDKAAP
+GENIDETFLDDIISNDGESDSKVDGSREDAIPEKSYDIFQALLTDALKLARYIANVSHNA
+VDKDYVMEELVYYIAYNTSKKYFDELLANPLVATFKEFEVNVKRLRKIAEVEMKCVYPPS
+AWAYPKPKSSQVLCKNKVWDCPNIVMGWDIHVITAQEAFGWVGTSLPVDNYPKCRLEEEL
+DEIMVEPEKPKKK*
+>1234#10_00017 (null)
+MKRYLSIVILCTFAMLLLVCSTNKSSGSDQVKTESNATSARIVWLLGDVKILSDSGEKKA
+ELGASLSSTDRVVTGPNGGAEIMVADSGIIKMSKNSDIEISSLMNPNGSDTNVQVNYGKI
+VTMVKKGQKTTEFTVSTPTALAGVRGTSFLTSVESPEGSKINCAKANCTVRFAVIEGTIA
+VSKKGESSEVILSKNRELRIEKNQKLTDKLIRSLQNDSLSEMKELIVLHKNETFEYGKLV
+EELKSSSEELKILSQSGSVEEVKAAFQKREADRNNADEITKTAKAVNETKYVQQDVQKEK
+LKLNPKETF*
+>1234#10_00018 (null)
+MDFSFNLVDNNGTVMRSTFSPIRFFTFSFLWILIDCSSVQKIENFNSVLQEPTFKSLKEE
+EAILGGSSDSDYKIRKTGNTIPVFVLSPIQTPEGMDSKLAAFLSDEVRLIWAKVKGKQVR
+IQEMSWKNPSQLSQELKRLNVDAVIKTDIREVSGKWVVNQKITDPVKEIVYGSVDGSFQS
+PKIEDELQANQAYYLKHGSGVLALDAKSSLVPIWEKSLSSGEIDSILKKSIQGYLSFSAS
+SADTEVLFQGEKIGIASFRNYPLPEGLQQIQITRPGQKDISKSLQIRSGQTISIYQEWKE
+DRTLGGVRILSFPEALQVALDGLKMGETPFYRSNLTPGAMQLELVRETENGPLVYYEGQL
+IVDADKITEIALPYKTDNLISEPEFWKLSGEKGFQAFSGKTLDFQNVSSLPPGWYGVFSA
+PFVPENMELEGIIPITAESDSGIVAISFHTSKKTISLEYEKERLSVYSFPSNGNNVGTYK
+FKKEDKEDGRPFRIITDVKEGTIRLYLGYSKVLEDRLDVSGVWRISILTRGENFSKRSPL
+RNLKIEYKGYK*
+>1234#10_00001 (null)
+MSKHGFFQITQKLFLRKGDELLILRDRKSGLGDLPGGRMNENEFFEDWSLSMQREIEEEL
+GSQVQIRVSTKPLFIHKHKVNEGNFPCIIIAYHADYLGGDIILSDEHDYISWEKVQTYEP
+SPLFTEYMLDAVNLYLKEYAPLVH*
+>1234#10_00002 (null)
+MIIKLKIILNSYLIYYFLRGQNTLIRTLLFEFPLTTFFVFLMVATFFIVNVFLPEHLIRQ
+YFLNHPGQIQPLSWIGAVFYHGNLIHLFGNMFYLFFLGRAVEYKAGKGRWLLFFFMAALI
+SSLLDSFIRGVILHDPTPVVGASGAISGIAAVAALLSPFSLRFNQRNIPFPVFLVAWIMV
+YSDITNVFTEDGVARWAHLGGFISVIFAAYFLKPTERKQLHSGFILNLIFIILTLILAFF
+YSNRS*
+>1234#10_00003 (null)
+VKTTLSGEIEKLRYEVAVKIVNLQGEVLDLRAEMKINFSEVNSKILKLQFEFEMAKIRKE
+LKTEIADLRAETKTDFLELQKSIVDIYKTISTQTRWILGVATLFAAIGKVIN*
+>1234#10_00005 (null)
+LTDKLIGFYDPVRMKAERKTSETEIKLEMNLRGTGQYQFDTEIPFFEHMLSHISKHGLID
+LNLWLRGDIEIDCHHSVEDTAILMGATIHKQLGDKAGIFRYGHFTLTMDEVLTTVAVDLG
+GRYFFKYTGPELTGKFGIYDAELSLEFLQKLALNAKMNLHVVVHYGDNKHHVHESIFKAL
+GKALRMAIAQDSAAAGAIPSTKGVLE*
+>1234#10_00006 (null)
+MIAILDYGMGNIHSCLKAVSLYTKDFVFTKDHSTIENSKALILPGDGHFDKAMENLNSTG
+LRKTIDKHVTSGKPLFGICIGFQILFESSEEIAQGSKKEQIEGLGYIKGKIKKFHGKDFK
+VPHIGWNRLQIRRKDKSVLLKGIGDQSFFYFIHSYRPTDAEGNAITGLCDYYQEKFPAVV
+EKNNIFGTQFHPEKSHTHGLKLLENFIRFI*
+>1234#10_00007 (null)
+MIVIPAIDLFDNCAVRLFKGNYEEKKIYSSEPWKLAESFAKNGATLLHLVDLNGARNQLG
+VNEDSILKIRETTSLKVQLGGGIRDKEKLAYYDKIGINRFILGTAAVTNPDLLKYALDNY
+GKERVVVAVDARDGIVKIAGWEKDSGIHYRDLLERLVKAGIEHIVFTDIAQDGTLAGPNL
+EAYREILNSYPFQVIASGGIASLKDLMDLSSLKTKISLYGVITGKALYEGKLDLAKAISS
+I*
diff --git a/t/data/expected_example_annotation_1.faa b/t/data/expected_example_annotation_1.faa
new file mode 100644
index 0000000..cc39033
--- /dev/null
+++ b/t/data/expected_example_annotation_1.faa
@@ -0,0 +1,30 @@
+>abc_00001 [revcomp]:[translate(1)]
+MKTRIVSSVTTTLLLGSILMNPVANAADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAAENFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTN*
+>abc_00002 [translate(1)]
+MKLFYIVFLIIIWLNIFLGNEIIHTLTVLITTLYIVNSRKGIKNDRVE*
+>abc_00003 [translate(1)]
+MTELNNIINSLQSLFESESGYKISKNSGVPYQTVQDLRNGKTKLEDARFRTIIKLYSYYVSLKEH*
+>abc_00004 [revcomp]:[translate(1)]
+MSKNITKNIILTTTLLLLGTVLPQNQKPVFSFYSEAKAYSIGQDETNINELIKYYTQPHFSFSNKWLYQYDNGNIYVELKRYSWSAHISLWGAESWGNINQLKDRYVDVFGLKDKDTDQLWWSYRETFTGGVTPAAKPSDKTYNLFVQYKDKLQTIIGAHKIYQGNKPVLTLKEIDFRAREALIKNKILYTENRNKGKLKITGGGNNYTIDLSKRLHSDLANVYVKNPNKITVDVLFD*
+>abc_00005 [revcomp]:[translate(1)]
+MNNNITKKIILSTTLLLLGTAFTQFPNTPINSSSEAKAYYINQNETNVNELTKYYSQKYLTFSNSTLWQKDNGTIHATLLQFSWYSHIQVYGPESWGNINQLRNKSVDIFGIKDQETIDSFALSQETFTGGVTPAATSNDKHYKLNVTYKDKAETFTGGFPVYEGNKPVLTLKELDFRIRQTLIKSKKLYNNSYNKGQIKITGTDNNYTIDLSKRLPSTDANRYVKKPQNAKIEVILEKSN*
+>abc_00006 [revcomp]:[translate(1)]
+MKKNIMNKLVLSTALLLLGTTSTQLPKTPISFSSEAKAYNISENETNINELIKYYTQPHFSLSGKWLWQKPNGSIHATLQTWVWYSHIQVFGSESWGNINQLRNKYVDIFGTKDEDTVEGYWTYDETFTGGVTPAATSSDKPYRLFLKYSDKQQTIIGGHEFYKGNKPVLTLKELDFRIRQTLIKNKKLYNGEFNKGQIKITADGNNYTIDLSKKLKLTDTNRYVKNPKNAQIEVILEKSN*
+>abc_00007 [translate(1)]
+MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTRCAFEVAAHDQGANVTYLGPTGSQMGKKETTKDTARVLGGMYDGIEYRGFSQRTVETLAENSGVPVWNGLTDEDHPTQVLADFLTAKEVLKKDYADINFTYVGDGRNNVANALMQGAAIMGMNFHLVCPKELNPTDELLNRCKNIAAENGGNILITDDIDQGVKGSDVIYTDVWVSMGEPDEVWKERLELLKPYQVNKEMMDKTGNPNVIFEHCLPSFHNADTKIGQQIFEKYGIREMEVTDEVFESKASVVFQEAENRMHTIKAVMVATLGEF*
+>abc_00008 [translate(1)]
+MMAKIVVALGGNALGKSPQEQLELVKNTAKSLVGLITKGHEIVISHGNGPQVGSINLGLNYAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVDENDPAFNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVPSPQPISIIELESIKTLIKNDTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDYVYINFNTENQQPLKTTNVDELKRYIDENQFAKGSMLPKIEAAISFIENNPKGSVLITSLNELDAALEGKVGTVIKK*
+>abc_01705 [translate(1)]
+VENTINESEKKKRFKLKMPGAFMILFILTVVAVIATWVIPAGAYSKLSYEPSSQELKIVNPHNQVKKVPGTQQELDKMGVKIKIEQFKSGAINKPVSIPNTYERLKQHPAGPEQITSSMVEGTIEAVDIMVFILVLGGLIGVVQASGSFESGLLALTKKTKGHEFMLIVFVSILMIIGGTLCGIEEEAVAFYPILVPIFIALGYDSIVSVGAIFLASSVGSTFSTINPFSVVIASNAAGTTFTDGLYWRIGACIVGAIFVISYLYWYCKKIKNDPKASYSYEDKDAFEQQWSVLKDDDSAHFTLRKKIILTLFVLPFPIMVWGVMTQGWWFPVMASAFLIFTIIIMFIAGTGKSGLGEKGTVDAFVNGASSLVGVSLIIGLARGINLVLNEGMISDTILHFSSSLVQHMSGPLFIIVLLFIFFCLGFIVPSSSGLAVLSMPIFAPLADTVGIPRFVIVTTYQFGQYAMLFLAPTGLVMATLQMLNMRYSHWF [...]
+>abc_00010 [translate(1)]
+MTHLTKVLDTLTGICVVLLFSKYFVAYANMVFDWNLRWYLLENIPHLPIILFILMFIFGVPSEMIKDRQRKNNGV*
+>abc_00011 [revcomp]:[translate(1)]
+MRLQKAPLVTSGLVLGLLGLGNLLKDLSLTLNAVCGIFAFLIWIHLLCTMIKYFNNVKEQLNSPLVSSVFTTFFMSGFLGTTYLNTFFSNITFINSLITPIWILCLVGIMTHMIIFSIKYLKDFSLENVYPSWTVLFIGIAIAGLTAPVSGCFFIGQLTVIYGFVATCIVLPIVFKRLKAFPLQTSIKPNTSTICAPFSLVAAAYVIAFPKANAFIVIIFLILAQIFYFYIIIQLPKLLKEPFSPVFSAFTFPLVISATALKNSLPVLMFPDIWKGLLFIEVLLATVIVLRVFIGYLHFFLKKENQDKFLRNASQ*
+>abc_00012 [translate(1)]
+MRNQIQKLLDSDLSSLHISKQTGVPQSTIHRMRKKERSLDNMSLKNAELLYKFANSIFSNEN*
+>abc_00014 [translate(1)]
+MEGLFNAIKDTVTAAINNDGAKLGTSIVSIVENGVGLLGKLFGF*
+>abc_00015 [translate(1)]
+MTGLAEAIANTVQAAQQHDSVKLGTSIVDIVANGVGLLGKLFGF*
+>abc_00016 [translate(1)]
+LGYKNILIDFDDTIVDFYDAEEWAFHYMANVFNHKATKDDFLTFKKINHQHWEAFQQNKLTKSEVLSERFVNYFKHHQMEVDGHRADVLFRNGLAEAKVKYFDQTLETIVELSKRHDLYIVTNGVTETQKRRLNQTPLHKYIKKIFISEETGYQKPNPEFFNYVFNDIGEDERQHSIIVGDSLTSDILGGINAGIATCWFNFRGFDHNPGIIPDYEINSWKQLNDIVR*
diff --git a/t/data/expected_filtered_original_input.fa b/t/data/expected_filtered_original_input.fa
new file mode 100644
index 0000000..ec8984e
--- /dev/null
+++ b/t/data/expected_filtered_original_input.fa
@@ -0,0 +1,48 @@
+>4075_1#3_04238
+AAAGGGTTT
+>4075_1#6_04091
+AAAGGGTTT
+>2212_1_02994
+AAAGGGTTT
+>2363_5_00947
+AAAGGGTTT
+>2363_7_00085
+AAAGGGTTT
+>2460_2_00826
+AAAGGGTTT
+>2212_3_02841
+AAAGGGTTT
+>4075_2#3_03437
+AAAGGGTTT
+>2363_5_03666
+AAAGGGTTT
+>2212_6_02081
+AAAGGGTTT
+>2541_8_00644
+AAAGGGTTT
+>2781_2_02909
+AAAGGGTTT
+>3634_6_00968
+AAAGGGTTT
+>3634_7_01056
+AAAGGGTTT
+>3634_8_02606
+AAAGGGTTT
+>4075_1#8_03461
+AAAGGGTTT
+>2363_1_00606
+AAAGGGTTT
+>2363_2_02124
+AAAGGGTTT
+>2363_3_01371
+AAAGGGTTT
+>2363_6_01272
+AAAGGGTTT
+>2363_8_00966
+AAAGGGTTT
+>2541_2_02425
+AAAGGGTTT
+>2541_3_02449
+AAAGGGTTT
+>2541_7_00441
+AAAGGGTTT
diff --git a/t/data/expected_g2_g5_pan_genome_reference.fa b/t/data/expected_g2_g5_pan_genome_reference.fa
new file mode 100644
index 0000000..5e6c0e7
--- /dev/null
+++ b/t/data/expected_g2_g5_pan_genome_reference.fa
@@ -0,0 +1,70 @@
+>1_1 hly
+ATGAAAACACGTATAGTCAGCTCAGTAACAACAACACTATTGCTAGGTTCCATATTAATG
+AATCCTGTCGCTAATGCCGCAGATTCTGATATTAATATTAAAACCGGTACTACAGATATT
+GGAAGCAATACTACAGTAAAAACAGGTGATTTAGTCACTTATGATAAAGAAAATGGCATG
+CACAAAAAAGTATTTTATAGTTTTATCGATGATAAAAATCACAATAAAAAACTGCTAGTT
+ATTAGAACGAAAGGTACCATTGCTGGTCAATATAGAGTTTATAGCGAAGAAGGTGCTAAC
+AAAAGTGGTTTAGCCTGGCCTTCAGCCTTTAAGGTACAGTTGCAACTACCTGATAATGAA
+GTAGCTCAAATATCTGATTACTATCCAAGAAATTCGATTGATACAAAAGAGTATATGAGT
+ACTTTAACTTATGGATTCAACGGTAATGTTACTGGTGATGATACAGGAAAAATTGGCGGC
+CTTATTGGTGCAAATGTTTCGATTGGTCATACACTGAAATATGTTCAACCTGATTTCAAA
+ACAATTTTAGAGAGCCCAACTGATAAAAAAGTAGGCTGGAAAGTGATATTTAACAATATG
+GTGAATCAAAATTGGGGACCATATGATAGAGATTCTTGGAACCCGGTATATGGCAATCAA
+CTTTTCATGAAAACTAGAAATGGTTCTATGAAAGCAGCAGAGAACTTCCTTGATCCTAAC
+AAAGCAAGTTCTCTATTATCTTCAGGGTTTTCACCAGACTTCGCTACAGTTATTACTATG
+GATAGAAAAGCATCCAAACAACAAACAAATATAGATGTAATATACGAACGAGTTCGTGAT
+GACTACCAATTGCATTGGACTTCAACAAATTGGAAAGGTACCAATACTAAAGATAAATGG
+ACAGATCGTTCTTCAGAAAGATATAAAATCGATTGGGAAAAAGAAGAAATGACAAATTAA
+>1_2 speH
+ATGAACAATAACATCACGAAAAAAATTATTTTATCAACAACATTGTTACTATTAGGTACA
+GCATTTACACAATTTCCTAATACACCTATCAATTCTTCATCTGAAGCGAAAGCTTATTAT
+ATAAATCAAAACGAAACTAACGTTAATGAGTTAACTAAATATTACTCGCAAAAATATTTA
+ACCTTCTCTAACAGTACGTTATGGCAAAAAGATAACGGTACGATTCATGCAACGTTGTTA
+CAGTTTTCTTGGTATAGTCATATTCAAGTTTATGGACCTGAAAGTTGGGGCAATATCAAC
+CAATTAAGAAATAAAAGCGTTGATATTTTTGGCATAAAAGACCAAGAAACCATTGATTCT
+TTTGCATTATCTCAAGAAACGTTTACTGGTGGTGTTACTCCTGCAGCAACATCTAACGAT
+AAACACTATAAACTGAATGTAACATATAAAGATAAAGCAGAAACGTTTACTGGCGGATTT
+CCAGTTTATGAAGGCAATAAGCCTGTTTTAACTTTAAAAGAATTAGATTTTCGTATTCGT
+CAAACATTAATTAAAAGTAAAAAATTATATAATAATTCTTATAATAAAGGACAAATTAAA
+ATAACAGGTACAGACAATAACTACACAATAGATTTAAGTAAAAGGTTGCCATCAACTGAT
+GCAAATAGATATGTTAAAAAACCTCAAAATGCAAAAATTGAAGTTATCCTCGAAAAATCA
+AACTAA
+>1_3 argF
+ATGAAAAATTTACGAAACAGAAGTTTTTTAACTTTATTAGACTTTTCACGACAAGAGGTA
+GAATTCTTATTAACACTCTCCGAGGATTTAAAACGTGCTAAATATATTGGCACTGAAAAG
+CCTATGTTAAAAAATAAAAATATTGCACTGTTATTTGAAAAAGATTCTACAAGAACGCGA
+TGTGCATTTGAAGTTGCAGCGCATGATCAAGGTGCAAATGTAACTTATTTAGGCCCAACT
+GGATCACAAATGGGTAAAAAAGAAACAACTAAAGATACTGCACGTGTGCTTGGTGGAATG
+TATGATGGCATTGAATACCGTGGTTTTTCACAAAGAACAGTAGAAACTTTAGCTGAAAAT
+TCAGGCGTACCAGTGTGGAATGGTTTAACTGATGAAGATCATCCTACTCAAGTTCTTGCT
+GATTTCTTAACAGCAAAAGAAGTCTTAAAAAAAGATTATGCAGATATTAACTTTACATAT
+GTTGGAGATGGTCGTAATAACGTTGCAAATGCATTAATGCAAGGTGCTGCCATTATGGGT
+ATGAACTTCCATTTAGTTTGTCCAAAAGAATTAAATCCAACAGATGAATTATTAAATCGC
+TGTAAAAATATTGCCGCTGAAAATGGTGGCAACATATTAATCACAGATGATATTGACCAA
+GGTGTAAAAGGTTCGGATGTAATTTACACTGATGTTTGGGTATCAATGGGTGAACCTGAT
+GAAGTATGGAAAGAACGACTTGAATTATTGAAACCATATCAAGTAAATAAAGAAATGATG
+GATAAAACTGGTAATCCAAATGTTATTTTTGAGCATTGCTTACCATCTTTCCATAATGCT
+GATACGAAAATTGGTCAACAAATTTTTGAAAAATATGGTATTCGAGAAATGGAAGTTACA
+GATGAAGTATTCGAAAGTAAAGCTTCAGTTGTATTCCAAGAAGCTGAGAACAGAATGCAT
+ACAATCAAAGCAGTCATGGTTGCTACATTGGGTGAATTTTAA
+>1_6 group_6
+ATGACTGGACTAGCAGAAGCAATCGCAAATACTGTGCAAGCTGCACAACAACATGATAGT
+GTGAAATTAGGCACAAGTATCGTAGACATCGTTGCTAACGGTGTGGGTTTACTAGGTAAA
+TTATTTGGATTCTAA
+>2_7 group_7
+ATGACTGGACTAGCAGAAGCAATCGCAAATACTGTGCAAGCTGCACAACAACATGATAGT
+GTGAAATTAGGCACAAGTATCGTAGACATCGTTGCTAACGGTGTGGGTTTACTAGGTAAA
+TTATTTGGATTCTAA
+>3_5 yfnB
+TTGGGATATAAAAATATTTTGATAGACTTTGATGATACAATTGTTGATTTTTATGATGCA
+GAAGAATGGGCGTTTCACTATATGGCGAATGTTTTTAATCATAAAGCAACAAAGGATGAT
+TTTTTAACATTTAAAAAAATCAATCACCAACATTGGGAAGCTTTTCAACAAAATAAATTA
+ACGAAGTCTGAAGTATTATCAGAACGATTTGTGAATTACTTCAAACATCATCAAATGGAA
+GTTGATGGGCATCGTGCAGATGTGTTATTTAGAAATGGATTAGCAGAAGCTAAAGTTAAA
+TACTTTGATCAAACATTAGAAACAATTGTCGAATTATCGAAAAGACATGATTTATATATT
+GTTACTAATGGTGTAACCGAAACGCAAAAGAGAAGGTTAAATCAGACGCCGTTGCATAAA
+TATATTAAAAAGATATTTATATCTGAGGAAACAGGATATCAAAAACCTAATCCGGAATTT
+TTTAATTATGTTTTTAATGATATTGGTGAGGATGAAAGACAGCACTCGATTATAGTTGGA
+GATTCTTTAACATCTGACATTCTAGGTGGAATCAATGCGGGTATAGCTACTTGCTGGTTT
+AATTTTAGAGGATTTGATCATAATCCAGGAATTATACCTGATTATGAAATTAATTCATGG
+AAACAACTAAATGATATTGTACGTTAA
diff --git a/t/data/expected_gene_presence_and_absence.Rtab b/t/data/expected_gene_presence_and_absence.Rtab
new file mode 100644
index 0000000..0d9c5ff
--- /dev/null
+++ b/t/data/expected_gene_presence_and_absence.Rtab
@@ -0,0 +1,8 @@
+Gene query_1.fa query_2.fa query_3.fa
+hly 1 1 1
+speH 1 1 0
+argF 1 0 1
+group_4 0 1 1
+yfnB 0 0 1
+group_6 1 0 0
+group_7 0 1 0
diff --git a/t/data/expected_gff_set_difference_common_set_statistics.csv b/t/data/expected_gff_set_difference_common_set_statistics.csv
new file mode 100644
index 0000000..8bdba55
--- /dev/null
+++ b/t/data/expected_gff_set_difference_common_set_statistics.csv
@@ -0,0 +1,4 @@
+"Gene","Non-unique Gene name","Annotation","No. isolates","No. sequences","Avg sequences per isolate","Genome Fragment","Order within Fragment","Accessory Fragment","Accessory Order with Fragment","QC","Min group size nuc","Max group size nuc","Avg group size nuc","query_1","query_2","query_3"
+"hly","","Alpha-toxin","3","3","1","","","","","","959","959","959","1_1","2_1","3_1"
+"speH","","hypothetical protein","2","2","1","","","","","","725","725","725","1_2","2_2",""
+"argF","","Ornithine carbamoyltransferase","2","2","1","","","","","","1001","1001","1001","1_3","","3_3"
diff --git a/t/data/expected_group_labels b/t/data/expected_group_labels
new file mode 100644
index 0000000..adbc922
--- /dev/null
+++ b/t/data/expected_group_labels
@@ -0,0 +1,6 @@
+group_1: 1234#10_00001 1234#10_00002
+group_2: 1234#10_00003 1234#10_00018 1234#10_00005
+group_3: 1234#10_00005 1234#10_00005
+group_4: 1234#10_00006 1234#10_00007
+group_5: 1234#10_00016
+group_6: 1234#10_00017
\ No newline at end of file
diff --git a/t/data/expected_group_statitics.csv b/t/data/expected_group_statitics.csv
new file mode 100644
index 0000000..588e641
--- /dev/null
+++ b/t/data/expected_group_statitics.csv
@@ -0,0 +1,8 @@
+"Gene","Non-unique Gene name","Annotation","No. isolates","No. sequences","Avg sequences per isolate","Genome Fragment","Order within Fragment","Accessory Fragment","Accessory Order with Fragment","QC","Min group size nuc","Max group size nuc","Avg group size nuc","query_1.fa","query_2.fa","query_3.fa"
+"hly","","Alpha-toxin","3","3","1","","","","","","959","959","959","1_1","2_1","3_1"
+"speH","","hypothetical protein","2","2","1","","","","","","725","725","725","1_2","2_2",""
+"argF","","Ornithine carbamoyltransferase","2","2","1","","","","","","1001","1001","1001","1_3","","3_3"
+"group_4","","","2","2","1","","","","","","","","","","2_4","3_4"
+"yfnB","","Putative HAD-hydrolase yfnB","1","1","1","","","","","","686","686","686","","","3_5"
+"group_6","","Gonococcal growth inhibitor III","1","1","1","","","","","","134","134","134","1_6","",""
+"group_7","","Gonococcal growth inhibitor III","1","1","1","","","","","","134","134","134","","2_7",""
diff --git a/t/data/expected_group_statitics_missing_genes.csv b/t/data/expected_group_statitics_missing_genes.csv
new file mode 100644
index 0000000..d23a540
--- /dev/null
+++ b/t/data/expected_group_statitics_missing_genes.csv
@@ -0,0 +1,8 @@
+"Gene","Non-unique Gene name","Annotation","No. isolates","No. sequences","Avg sequences per isolate","Genome Fragment","Order within Fragment","Accessory Fragment","Accessory Order with Fragment","QC","Min group size nuc","Max group size nuc","Avg group size nuc","query_1.fa","query_2.fa","query_3.fa","query_4_missing_genes.fa"
+"hly","","Alpha-toxin","4","4","1","","","","","","959","959","959","1_1","2_1","3_1","4_1"
+"speH","","hypothetical protein","2","2","1","","","","","","725","725","725","1_2","2_2","",""
+"argF","","Ornithine carbamoyltransferase","2","2","1","","","","","","1001","1001","1001","1_3","","3_3",""
+"group_4","","","2","2","1","","","","","","","","","","2_4","3_4",""
+"yfnB","","Putative HAD-hydrolase yfnB","1","1","1","","","","","","686","686","686","","","3_5",""
+"group_6","","Gonococcal growth inhibitor III","1","1","1","","","","","","134","134","134","1_6","","",""
+"group_7","","Gonococcal growth inhibitor III","1","1","1","","","","","","134","134","134","","2_7","",""
diff --git a/t/data/expected_group_statitics_verbose.csv b/t/data/expected_group_statitics_verbose.csv
new file mode 100644
index 0000000..6e257ae
--- /dev/null
+++ b/t/data/expected_group_statitics_verbose.csv
@@ -0,0 +1,8 @@
+"Gene","Non-unique Gene name","Annotation","No. isolates","No. sequences","Avg sequences per isolate","Genome Fragment","Order within Fragment","Accessory Fragment","Accessory Order with Fragment","QC","Min group size nuc","Max group size nuc","Avg group size nuc","query_1.fa","query_2.fa","query_3.fa","Inference"
+"hly","","Alpha-toxin,beta-channel forming cytolysin,Leukocidin/Hemolysin toxin family protein","3","3","1","","","","","","959","959","959","1_1","2_1","3_1","ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:Q2G1X0,protein motif:TIGRFAMs:TIGR01002,protein motif:Pfam:PF07968.6"
+"speH","","hypothetical protein,superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain","2","2","1","","","","","","725","725","725","1_2","2_2","","ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P0C0I6,protein motif:CLUSTERS:PRK13349,protein motif:Pfam:PF02876.11"
+"argF","","Ornithine carbamoyltransferase,ornithine carbamoyltransferase,Ornithine carbamoyltransferase,ornithine carbamoyltransferase,Aspartate/ornithine carbamoyltransferase%2C Asp/Orn binding domain","2","2","1","","","","","","1001","1001","1001","1_3","","3_3","ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P99073,protein motif:CLUSTERS:PRK04284,protein motif:Cdd:COG0078,protein motif:TIGRFAMs:TIGR00658,protein motif:Pfam:PF00185.1"
+"group_4","","","2","2","1","","","","","","","","","","2_4","3_4",
+"yfnB","","Putative HAD-hydrolase yfnB,dUMP phosphatase,HAD hydrolase,haloacid dehalogenase-like hydrolase","1","1","1","","","","","","686","686","686","","","3_5","ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:O06480,protein motif:CLUSTERS:PRK09449,protein motif:TIGRFAMs:TIGR02254,protein motif:Pfam:PF00702.1"
+"group_6","","Gonococcal growth inhibitor III,Staphylococcus haemolytic protein","1","1","1","","","","","","134","134","134","1_6","","","ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P11699,protein motif:Pfam:PF05480.5"
+"group_7","","Gonococcal growth inhibitor III,Staphylococcus haemolytic protein","1","1","1","","","","","","134","134","134","","2_7","","ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P11699,protein motif:Pfam:PF05480.5"
diff --git a/t/data/expected_inflated_results b/t/data/expected_inflated_results
new file mode 100644
index 0000000..4dbcc2e
--- /dev/null
+++ b/t/data/expected_inflated_results
@@ -0,0 +1,5 @@
+6259_8#9_01142 6631_2#11_00851 6631_4#5_01901
+6664_1#21_00211
+6259_8#13_01077
+6630_4#9_00008 6631_1#23_00379 6631_2#7_00715 6631_5#1_00087 6649_8#10_00838 6664_1#13_00087 6259_5#1_00688 6259_5#8_00815
+6259_7#7_02078 6259_7#8_01884 6631_2#22_01965 6631_5#24_01032 6593_5#13_00457 6630_1#9_00031 6630_3#1_00008 6630_3#2_00088 6631_1#4_00087
diff --git a/t/data/expected_intersection_of_groups.gg b/t/data/expected_intersection_of_groups.gg
new file mode 100644
index 0000000..66e7a90
--- /dev/null
+++ b/t/data/expected_intersection_of_groups.gg
@@ -0,0 +1 @@
+group_1: 1_1 2_1 3_1
diff --git a/t/data/expected_intersection_of_groups_core0.66.gg b/t/data/expected_intersection_of_groups_core0.66.gg
new file mode 100644
index 0000000..ea0fd7a
--- /dev/null
+++ b/t/data/expected_intersection_of_groups_core0.66.gg
@@ -0,0 +1,4 @@
+group_1: 1_1 2_1 3_1
+group_3: 1_3 3_3
+group_4: 2_4 3_4
+group_2: 1_2 2_2
diff --git a/t/data/expected_intersection_of_groups_paralogs.gg b/t/data/expected_intersection_of_groups_paralogs.gg
new file mode 100644
index 0000000..c79cc10
--- /dev/null
+++ b/t/data/expected_intersection_of_groups_paralogs.gg
@@ -0,0 +1,2 @@
+group_3: 1_3 2_4 3_3
+group_1: 1_1 2_1 3_1
diff --git a/t/data/expected_mafft_input.fa.aln b/t/data/expected_mafft_input.fa.aln
new file mode 100644
index 0000000..33a59d7
--- /dev/null
+++ b/t/data/expected_mafft_input.fa.aln
@@ -0,0 +1,66 @@
+>1111#5_04506
+------------------------------------------------------------
+------------------------------------------------------------
+------------------------------------------------------------
+------------------------------------------------------------
+------------------------------------------------------------
+------------------------------------------------------------
+------------------------------------------------------------
+---------atggcaatcaccttacgggagctggatggcctgagctatgaagagatagcg
+gctatcatggattgtccggtggggacggtgcgttcacgtatcttccgggcgcgggaagct
+attgataataaagttcaaccgcttatcaggcgttga
+>1234_8#75_04759
+atgagcgagcagttaacggaccaggtcctggttgaacgggtccagaagggagatcagaaa
+gcctttaacttactggtagtgcgctaccagcataaagtggcgagtctggtttcccgctat
+gtgccatcgggcgacgttcccgatgtcgtacaggaatcatttattaaggcctatcgcgcg
+ctggattctttccggcgggatagtgctttttatacctggttgtatcgtattgcggtcaat
+accgcgaagaactacctggttgcgcaggggcgtcgtccgccttccagtgatgtagacgcg
+attgaagcagaaaactttgaaagcggcggcgcgctgaaagaaatttcgaaccctgagaac
+ttaatgttgtcagaagaactgagacagatagttttccgaactattgagtccctcccggaa
+gatttacgtatggcaatcaccttacgggagctggatggcctgagctatgaagagatagcg
+gctatcatggattgtccggtggggacggtgcgttcacgtatcttccgggcgcgggaagct
+attgataataaagttcaaccgcttatcaggcgttga
+>Salmonella_enterica_subsp_enterica_serovar_Typhimurium_DT104_v1_02853
+atgagcgagcagttaacggaccaggtcctggttgaacgggtccagaagggagatcagaaa
+gcctttaacttactggtagtgcgctaccagcataaagtggcgagtctggtttcccgctat
+gtgccatcgggcgacgttcccgatgtcgtacaggaatcatttattaaggcctatcgcgcg
+ctggattctttccggggggatagtgctttttatacctggttgtatcgtattgcggtcaat
+accgcgaagaactacctggttgcgcaggggcgtcgtccgccttccagtgatgtagacgcg
+attgaagcagaaaactttgaaagcggcggcgcgctgaaagaaatttcgaaccctgagaac
+ttaatgttttcagaagaactgagacagatagttttccgaactattgagtccctcccggaa
+gatttacgtatggcaatcaccttacgggagctggatggcctgagctatgaagagatagcg
+gctatcatggattgtccggtggggacggtgcgttcacgtatcttccgggcgcgggaagct
+attgataataaagttcaaccgcttatcaggcgttga
+>Salmonella_enterica_subsp_enterica_serovar_Typhimurium_SL1344_v2_02736
+atgagcgagcagttaacggaccaggtcctggttgaacgggtccagaagggagatcagaaa
+gcctttaacttactggtagtgcgctaccagcataaagtggcgagtctggtttcccgctat
+gtgccatcgggcgacgttcccgatgtcgtacaggaatcatttattaaggcctatcgcgcg
+ctggattctttccggggggatagtgctttttatacctggttgtatcgtattgcggtcaat
+accgcgaagaactacctggttgcgcaggggcgtcgtccgccttccagtgatgtagacgcg
+attgaagcagaaaactttgaaagcggcggcgcgctgaaagaaatttcgaaccctgagaac
+ttaatgttgtcagaagaactgagacagatagttttccgaactattgagtccctcccggaa
+gatttacgtatggcaatcaccttacgggagctggatggcctgagctgtgaagagatagcg
+gctatcatggattgtccggtggggacggtgcgttcacgtatcttccgggcgcgggaagct
+attgataataaagttcaaccgcttatcaggcgttga
+>Salmonella_enterica_subsp_enterica_serovar_Typhimurium_str_D23580_v1_02783
+atgagcgagcagttaacggaccaggtcctggttgaacgggtccagaagggagatcagaaa
+gcctttaacttactggtagtgcgctaccagcataaagtggcgagtctggtttcccgctat
+gtgccatcgggcgacgttcccgatgtcgtacaggaatcatttattaaggcctatcgcgcg
+ctggattctttccggggggatagtgctttttatacctggttgtatcgtattgcggtcaat
+accgcgaagaactacctggttgcgcaggggcgtcgtccgccttccagtgatgtagacgcg
+attgaagcagaaaactttgaaagcggcggcgcgctgaaagaaatttcgaaccctgagaac
+ttaatgttgtcagaagaactgagacagatagttttccgaactattgagtccctcccggaa
+gatttacgtatggcaatcaccttacgggagctggatggcctgagctatgaagagatagcg
+gctatcatggattgtccggtggggacggtgcgttcacgtatcttccgggcgcgggaagct
+attgataataaagttcaaccgcttatcaggcgttga
+>Salmonella_enterica_subsp_enterica_serovar_Typhimurium_str_DT2_v1_02741
+atgagcgagcagttaacggac---gtcctggttgaacgggtccagaagggagatcagaaa
+gcctttaacttactggtagtgcgctaccagcataaagtggcgagtctggtttcccgctat
+gtgccatcgggcgacgttcccgatgtcgtacaggaatcatttattaaggcctatcgcgcg
+ctggattctttccggggggatagtgctttttatacctggttgtatcgtattgcggtcaat
+accgcgaagaactacctggttgcgcaggggcgtcgtccgccttccagtgatgtagacgcg
+attgaagcagaaaactttgaaagcggcggcgcgctgaaagaaatttcgaaccctgagaac
+ttaatgttgtcagaagaactgagacagatagttttccgaactattgagtccctcccggaa
+gatttacgtatggcaatcaccttacgggagctggatggcctgagctatgaagagatagcg
+gctatcatggattgtccggtggggacggtgcgttcacgtatcttccgggcgcgggaagct
+attgataataaagttcaaccgcttatcaggcgttga
diff --git a/t/data/expected_mafft_real_data_core_gene_alignment.aln b/t/data/expected_mafft_real_data_core_gene_alignment.aln
new file mode 100644
index 0000000..5fcda15
--- /dev/null
+++ b/t/data/expected_mafft_real_data_core_gene_alignment.aln
@@ -0,0 +1,2170 @@
+>real_data_1
+ATGAAAAAATCATTACTCGCTGTTGCTGTGGCAGGGGCTGTTTTGTTGTCATCCGCCGTA
+CAGGCGCAGACAACGCCGGAAGGTTATCAATTACAACAGGTGCTGATGATGAGCCGCCAT
+AATCTGCGGGCGCCGCTGGCGAATAATGGCAACGTACTGGCGCAGTCGACGCCGAACGCC
+TGGCCGGCGTGGGACGTTCCCGGCGGGCAACTGACGACGAAAGGCGGCGTGCTGGAAGTC
+TATATGGGACACTACACACGTGAATGGCTGGTCGCGCAGGGGCTGATACCGTCGGGAGAA
+TGTCCGGCGCCCGACACGGTATATGCCTATGCGAATAGTTTGCAGCGCACCGTCGCCACC
+GCGCAATTTTTCATTACCAGCGCTTTCCCCGGCTGTGATATTCCTGTTCATCATCAGGAA
+AAAATGGGCACTATGGACCCTACCTTCAATCCGGTGATTACCGATGATTCCGCCGCGTTC
+CGGCAACAGGCCGTACAGGCGATGGAAAAGGCGCGTAGTCAGCTACATCTTGATGAGAGT
+TATAAACTGCTTGAGCAGATAACGCATTATCAGGACTCGCCGTCCTGCAAAGAGAAGCAT
+CAGTGTTCGCTAATCGACGCGAAAGATACCTTCAGCGCGAACTATCAGCAAGAGCCTGGC
+GTGCAGGGGCCGCTGAAAGTAGGGAACTCGCTGGTGGATGCGTTTACCCTGCAATATTAC
+GAAGGCTTTCCGATGGATCAGGTCGCTTGGGGCGGGATCCACACCGATCGGCAGTGGAAG
+GTGCTGTCAAAACTGAAAAACGGCTACCAGGACAGCCTGTTTACCTCACCCACGGTGGCG
+CGCAATGTCGCTGCGCCGCTGGTAAAATATATCGATAAGGTGCTGGTTGCCGAGCGCGTT
+AGCGCGCCGAAGGTTACCGTGCTGGTGGGGCATGATTCCAATATCGCGTCGCTGCTGACG
+GCGCTGGATTTTAAACCCTATCAGCTCCATGACCAGTATGAGAGAACGCCGATTGGTGGT
+CAGCTTGTCTTCCAACGCTGGCATGACGGTAACGCTAACCGGGATTTGATGAAAATCGAG
+TATGTCTACCAGAGCGCCCGGCAGTTACGTAATGCGGAAGCGTTAACGCTCAAATCGCCT
+GCGCAAAGGGTAACGCTGGAACTGAAAGGATGTCCGGTGGATGCGAACGGCTTCTGTCCG
+CTGGATAAGTTCGATAACGTCATGAACACTGCTGCAAAATAGATGGAAAAGAATAATGAA
+GTCATTCAGACCCATCCGCTTGTAGGATGGGACATCAGCACCGTCGATAGCTATGATGCG
+CTGATGCTGCGTTTACACTACCAGACCCCAAATCGTCCGGAACCGGAAGGGACTGAAGTT
+GGTCAAACGCTCTGGTTAACGACAGATGTAGCCAGGCAATTTATTTCAATATTAGAAGCC
+GGCATCGCCAAAATAGAATCAGGCGATTACCAGGAAAACGAGTATCGTCACCATTAGATG
+GAACTTAAGGATTATTACGCCATTATGGGCGTGAAACCGACGGACGATCTCAAGACGATT
+AAGACCGCCTATCGCCGACTGGCCCGCAAGTACCATCCAGATGTCAGCAAAGAACCCGAT
+GCCGAAGCCCGTTTCAAAGAGGTTGCTGAAGCATGGGAAGTGCTGAGTGATGAGCAACGG
+CGCGCCGAGTATGACCAGTTATGGCAACACCGTAACGATCCACAATTTAATCGCCAGTTC
+CAGCAACACGAAGGCCAGCCGTATAACGCCGAAGATTTTGATGATATTTTCTCGTCTATT
+TTTGGTCAGCACGGTCGTCATTCGCACCACCGCCACGCCGCACGCGGTCATGATATCGAA
+ATTGAAGTGGCGGTATTCCTGGAAGAAACGCTGGAAGAGCACCAGCGTACGATTAGCTAT
+TCCGTCCCCGTTTATAACGCGTTCGGCCTGGTGGAGCGGGAAATTCCCAAAACATTGAAT
+GTGAAAATCCCGGCTGGCGTCAGCAACGGGCAACGAATCAGACTGAAAGGCCAGGGCACG
+CCGGGGGAAAACGGCGGACCTAATGGCGATTTATGGCTCGTTATCCATATTGCCCCGCAT
+CCGCTCTTTGATATCGTCAATCAGGATCTGGAAGTCGTCCTTCCGCTTGCCCCATGGGAG
+GCGGCGCTCGGCGCTAAGGTGTCTGTGCCAACGCTTAAAGAGCGTATTTTGCTGACCATT
+CCCCCCGGCAGCCAGGCAGGTCAGCGGCTGCGTATCAAAGGAAAAGGATTAGCCAGTAAA
+AAGCACACTGGCGATCTCTATGCCATCATCAAAATCGTTATGCCGCCGAAACCTGACGAG
+AAAACAGCTGCCCTGTGGCAACAACTGGCGGACGCGCAGTCGTCCTTTGACCCACGCCAG
+CAATGGGGGAAAGCATAAATGGCTAACATCACTGTCACCTTTACCATCACCGAATTTTGT
+TTGCACACCGGCGTGACGGAAGAGGAGCTAAACGAAATCGTCGGACTTGGCGTAATTGAG
+CCTTACGAAGACGATAACGCCGACTGGCAATTCGACGATCGCGCAGCGAGCGTGGTACAA
+CGCGCGCTACGCTTACGCGAGGAGCTGGCGCTCGACTGGCCAGGGATCGCGGTCGCGTTA
+ACGCTGCTGGAAGAGAATTCACGGCTGCGCGAAGAAAACCGGTTACTGCTGCAACGCCTT
+TCTCGCTTTATCTCGCATCCCTAAATGTCATCTTGTTGGAGATTTACGGATTCGCTAACA
+AGCCTATGGCATACTGCGTTGATGAAGATTTTATTGATTGAAGATAACCAGAAAACCATT
+GAGTGGGTACGTCAGGGACTCACGGAGGCAGGCTATGTGGTTGATTATGCCTGTGATGGA
+CGAGACGGATTACACCTAGCCCTTCAGGAACATTATTCATTGATTATTCTTGATATTATG
+CTGCCGGGGCTTGATGGATGGCAGGTTTTACGCGCGTTGCGCACTGCATATCAGCCCCCT
+GTTATTTGCCTGACGGCGCGCGACTCGGTTGAGGATCGCGTCAAAGGTCTTGAGGCGGGC
+GCTAATGATTACCTTGTTAAGCCTTTTTCCTTCGCCGAACTGCTGGCCCGGGTGAGAGCT
+CAACTCAGACAGCATGTCCCGGTCTTTACCCGACTGACGATCAATGGTCTGGACATGGAT
+GCCACAAAGCAATCGGTGTTACGAAATGGCAAACCGATTTCCCTGACCCGCAAAGAATTC
+CTGCTCCTCTGGTTACTGGCGTCCCGGGCAGGGGAAATCGTGCCCCGAACCGCGATCGCC
+AGCGAAGTTTGGGGAATTAACTTTGATAGTGAAACCAACACCGTTGATGTCGCGATTCGT
+CGGCTGCGCGCCAAAGTAGACGATCCATTTGAAAAGAAGCTCATTATGACCGTCCAGGGG
+ATGGGTTATCGATTACAGGCGGAAACGTCGCAGAATGGTTAAatgaaaaacaaattgtta
+tttatgatgttgacaatactgggtgcgcctgggattgcaaccgcgacaaattatgatctg
+gctcgttcagagtataattttgcggtaaatgaattaagcaagtcttcatttaatcaggcg
+gccattattggtcaagtcggcacggataatagtgccagagtacgccaggaaggatcaaaa
+ctattgtccgttatttcacaagaaggagaaaataatcgggcgaaagtcgaccaggcaggg
+aattataactttgcgtatattgagcaaacgggcaatgccaacgatgccagtatatcgcaa
+agcgcttacggtaatagtgcggctattatccagaaaggttctggaaataaggccaatatt
+acccagtacggtacgcagaaaacagcagttgtagtgcagaaacagtcgcatatggctatt
+cgcgtcacccaacgctaaatgcatactttattgctccttgccgcactttcaaatcagatt
+acgtttaccacgactcagcaaggcgatatttacacggtgatccctcaggtcacattaaac
+gaaccctgcgtctgtctggtgcaaattctctctgtgcgcgacggcgtcgggggacaaagc
+catacacagcaaaaacaaacgctatctttacctgctaatcaaccgattgagttgtctcgt
+cttagtgtaaatatatcttcagaggactcggttaaaattattgttactgtttcggacgga
+caatcactgcatttatcacaacaatggccgccttctgcacagtagatgtttaatgaagtc
+catagtagtcatggtcacacactattgttgatcacaaagccatctctgcaagctacggca
+ttattgcaacatttaaagcaatcgctggccataaccggaaaactgcataatattcaacgt
+tctctggaagatatctcagccggttgcattgttttaatggatatgatggaagcggataag
+aagcttatccactattggcaggataatttaagccgcaaaaacaataatataaaaacatta
+ttgttaaatacccctgacgattatccctaccgtgaaattgaaaactggcctcatattaac
+ggcgtgttttacgccactgaagaccaggaacacgtggtcagcggattacagggtattctg
+cggggcgaatgctatttttcacaaaaattagccagttacctgattacacactcaggaaat
+taccgctacaacagcaccgagtccgcattactcactcatcgcgaaaaagagatcctcaat
+aagttacgtattggtgcctctaataatgaaatcgccaggtcgctatttatcagcgagaat
+acggttaagacacatctttataatcttttcaaaaagatagctgtcaaaaatcgcacccag
+gcagtttcatgaatgaaacgctatctgacctggattgtagcagcagagttactgttcgct
+accggaaacctgcatgccaatgaagttgaagtcgaggttcccggattgttaaccgaccat
+accgtctcttcgataggacatgaattctatcgtgcattcagcgacaaatgggaaagcgaa
+tacaccggcaatctgaccattaatgaaagacccagtgcgcgttggggaagctggatcacc
+ataacggtaaatcaggacgttattttccagacctttttatttccaatgaaaagagacttc
+gagaaaaccgtcgtcttcgcattagcgcaaacagaggaagcattaaatcgccgacaaata
+gatcaaacgctattaagtacgagtgatttagcgcgtgatgaattctaaatgcgtgttaaa
+catgcagtagtgctgctcatgcttttttcgccattaacctgggctggaaatatgacgttc
+cagttccgtaatcctaactttggtggaaaccccaataacggttcctttttattgaatagc
+gcccaggcgcaaaattcatataaagaccccgcttatgataacgattttggtatcgagacc
+ccctcagcgttggataactttacgcaggctattcaatcgcaaattctgggcggcttgttg
+accaatattaataccggaaaaccaggacgtatggtgaccaatgattttattatcgatatc
+gctaatcgcgacggacagctccagctcaacgtcacggacagaaaaacgggaagaacctcg
+accatcgaagtgtcaggtttacaaactcagtcaaccgatttttaaatgccgcgcttactt
+attttggttgccgttttattgttgagcggatgcttaactgccccgccgaaacaagctgcg
+aaaccgacattaatgccccgcgcacaaagttacaaagatttgacgcacttacctgctccc
+accggtaagatctttgtttcggtatataacattcaggatgaaacgggccaatttaaacct
+tacccggcaagtaacttttccacggctgtgccgcagagcgccaccgctatgttggtcacc
+gcgctgaaagattcgcgctggtttatcccactagaacgacaaggcttacagaatcttttg
+aatgaacggaaaattattcgcgcagcccaggaaaacggcaccgtggcgatgaataaccgt
+atcccgcttcagtcgttgacggcggcaaatattatggtggaaggttctattattggttat
+gaaagtaacgtcaaatccggcggggtcggcgcaagatatttcggtattggcgccgatacg
+cagtatcagctggatcagattgctgtcaacctgcgcgtggttaacgtcagtacgggcgag
+atcctttcttcggtgaacaccagtaaaacgatcctttcctatgaagtacaggcaggcgtg
+ttccgttttattgattaccagcgcttactggaaggcgaaatcggctatacctcgaacgaa
+ccggtgatgctgtgtctgatgtcagccattgaaaccggcgttatcttcctcattaatgat
+ggtatcgatcgcggactgtgggatttgcagaataaagcggacaggcaaaatgatattctg
+gtgaaataccgtgagctgtcagtaccgccagaatcctgaATGTCTATTGCCGTAAATATG
+AATGACCCGACCAACACGGGCGTCAAAACGACGACCGGCAGCGGGTCGATGACCGGAAGC
+AACGCTGCCGATCTGCAAAGCAGTTTCCTGACCTTACTGGTCGCGCAATTGAAGAACCAG
+GACCCGACTAACCCATTACAAAATAATGAGTTAACGACACAGTTGGCGCAAATCAGTACC
+GTGAGCGGCATTGAAAAACTGAATACGACGCTGGGGGCTATTTCCGGGCAAATCGATAAT
+AGTCAGTCCCTACAGGCGACCACGCTGATTGGACATGGCGTTATGGTGCCTGGCACCACA
+ATTCTGGCGGGTAAAGGCGCGGAAGAAGGGGCCGTGACGTCCACGACGCCGTTTGGCGTG
+GAATTGCAACAGCCTGCGGACAAAGTGACGGCAACCATTACCGATAAAGATGGCCGGGTG
+GTACGGACGCTGGAGATCGGTGAGTTGCGAGCCGGGGTACACACCTTTACCTGGGATGGT
+AAGCAAACGGACGGAACAACGGTACCGAATGGTTCTTACAACATTGCGATTACCGCCAGC
+AATGGCGGGACGCAACTGGTGGCGCAGCCGCTGCAATTCGCTCTGGTACAGGGCGTGACG
+AAGGGCAGTAACGGCAACCTGTTGGATCTGGGTACCTACGGCACCACCACACTCGACGAA
+GTTCGGCAAATAATCTAAATGTCTTTTTCTCAAGCGGTTAGCGGCCTGAACGCTGCGGCC
+ACCAACCTTGATGTTATCGGTAATAACATCGCCAACTCCGCCACCTATGGCTTTAAGTCC
+GGTACGGCATCATTTGCCGATATGTTCGCCGGTTCCAAAGTGGGGTTGGGCGTAAAAGTG
+GCGGGGATTACCCAGGATTTTACCGACGGTACGACAACGAACACCGGGCGCGGGCTGGAT
+GTCGCGATTAGCCAGAACGGTTTTTTCCGCCTGGTAGACAGCAACGGTTCCGTGTTCTAT
+AGCCGCAACGGCCAGTTCAAACTGGACGAGAACCGTAACCTGGTCAATATGCAGGGGATG
+CAGTTGACCGGCTATCCGGCCACCGGTACGCCGCCGACCATTCAGCAGGGGGCGAATCCT
+GCGCCGATCACCATTCCGAACACGCTGATGGCGGCGAAATCGACCACCACCGCGTCAATG
+CAGATCAACCTGAACTCAACGGACCCTGTACCGTCTAAAACGCCCTTTAGCGTGAGTGAT
+GCGGATTCGTATAACAAAAAAGGCACCGTCACCGTTTATGACAGCCAGGGTAATGCCCAT
+GACATGAACGTCTATTTTGTGAAAACCAAAGATAATGAATGGGCTGTGTACACCCATGAC
+AGCAGCGATCCTGCAGCCACTGCGCCAACAACGGCGTCCACTACGCTGAAATTCAATGAA
+AACGGGATTCTGGAGTCTGGCGGTACGGTGAACATCACCACCGGTACGATTAATGGCGCG
+ACAGCGGCCACCTTCTCCCTCAGCTTCCTTAACTCCATGCAGCAGAACACCGGGGCTAAT
+AACATCGTCGCCACCAATCAAAACGGCTATAAGCCTGGCGACCTGGTGAGCTACCAGATT
+AACAATGATGGCACCGTGGTTGGCAACTACTCCAACGAGCAGGAGCAGGTGCTGGGGCAG
+ATTGTGCTGGCTAACTTCGCCAACAACGAAGGTCTGGCATCCCAGGGCGATAACGTCTGG
+GCGGCGACGCAGGCCTCCGGGGTAGCGCTGCTGGGGACTGCCGGTTCCGGCAACTTCGGT
+AAGCTGACGAACGGCGCGCTGGAAGCCTCTAACGTGGATTTGAGTAAAGAGCTGGTGAAT
+ATGATCGTCGCGCAGCGTAACTACCAGTCGAATGCGCAGACCATCAAAACCCAGGACCAG
+ATCCTCAATACGCTGGTTAACCTGCGCTAAATGGATCACGCAATTTATACCGCCATGGGG
+GCGGCCAGCCAGACGCTTAACCAGCAGGCGGTAACGGCCAGCAACCTGGCTAATGCCTCA
+ACGCCGGGCTTTCGCGCGCAGCTTAACGCGCTACGCGCGGTGCCCGTTGATGGCCTCTCT
+TTAGCGACGCGCACGTTGGTTACGGCGTCGACGCCGGGGGCGGATATGACCCAGGGTCAG
+TTGGACTACACTTCCCGCCCGCTGGATGTTGCGTTACAGCAGGACGGCTGGCTGGTGGTG
+CAAGCGGCGGATGGCGCTGAAGGATATACCCGTAACGGGAATATCCAGGTGGGCCCGACC
+GGGCAGTTAACCATTCAGGGACATCCGGTTATCGGCGAAGGCGGCCCGATTACCGTTCCG
+GAAGGGTCGGAAATCACCATTGCGGCAGACGGCACGATCTCCGCGCTCAATCCCGGCGAC
+CCGCCAAACACGGTGGCGCCCGTTGGGCGGCTGAAGCTGGTCAAAGCGGAAGGCAATGAG
+GTGCAGCGGAGCGATGACGGTTTATTCCGCCTTACCGCCGAGGCACAGGCTGAACGCGGG
+GCGGTACTGGCCGCCGACCCGTCAATTCGCATTATGTCGGGCGTGCTGGAGGGCAGTAAC
+GTCAAGCCGGTTGAAGCCATGACCGACATGATCGCCAACGCACGTCGTTTTGAAATGCAG
+ATGAAGGTTATCACCAGCGTAGATGAGAACGAAGGGCGAGCTAACCAACTGCTGTCGATG
+AGTTAAATGATCAGTTCATTATGGATCGCCAAAACCGGTCTGGACGCGCAGCAAACCAAT
+ATGGATGTGATTGCCAATAACCTGGCAAACGTCAGCACCAATGGTTTTAAGCGTCAGCGC
+GCGGTATTTGAAGATCTGTTGTATCAGACCATCCGCCAGCCGGGCGCGCAGTCGTCCGAG
+CAGACGACGCTGCCTTCCGGGCTGCAAATCGGTACCGGCGTGCGTCCGGTCGCCACGGAG
+CGCCTGCACAGTCAGGGGAACCTGTCGCAGACCAACAACAGTAAAGATGTGGCGATTAAA
+GGGCAGGGCTTTTTCCAGGTCATGCTGCCGGACGGTACGTCTGCCTATACCCGCGACGGC
+TCTTTCCAGGTGGATCAGAATGGTCAACTGGTGACGGCGGGCGGTTTTCAGGTGCAGCCG
+GCAATCACCATTCCGGCCAACGCGTTAAGCATCACGATTGGCCGCGACGGCGTGGTCAGC
+GTTACCCAGCAAGGGCAGGCCGCGCCGGTTCAGGTCGGGCAGCTTAACCTGACCACCTTT
+ATGAACGACACCGGTCTGGAAAGCATCGGCGAGAACCTCTATATCGAAACGCAATCGTCC
+GGCGCGCCGAACGAAAGCACGCCGGGGCTCAACGGCGCGGGGTTGTTGTATCAAGGGTAT
+GTCGAAACGTCGAACGTTAACGTGGCGGAAGAGCTGGTGAACATGATTCAGGTTCAACGC
+GCCTATGAAATTAACAGTAAAGCAGTATCGACGACCGATCAGATGCTGCAGAAACTGACG
+CAACTCTAAATGGCCCTGATGGTCGCGACGCTGACAGGATGCGCCTGGATACCCGCTAAA
+CCGCTCGTGCAGGGGGCGACCACGGCGCAGCCGATACCTGGCCCGGTACCGGTGGCGAAT
+GGCTCCATATTTCAGTCTGCGCAGCCGATTAATTATGGCTATCAGCCGCTTTTTGAAGAT
+CGTCGACCGCGTAATATCGGCGATACGCTCACGATTGTGTTACAGGAAAACGTCAGCGCC
+AGTAAAAGCTCGTCGGCAAATGCCAGCCGCGACGGCAAAACCAGCTTTGGTTTTGATACG
+GTACCGCGTTATCTGCAGGGATTATTCGGTAATTCCCGCGCGGATATGGAGGCCTCCGGC
+GGCAACTCTTTTAATGGTAAAGGCGGCGCGAATGCCAGCAATACCTTTAGCGGCACGCTG
+ACCGTGACCGTCGATCAGGTTCTGGCCAATGGCAATTTACACGTCGTGGGGGAAAAACAG
+ATCGCGATTAATCAGGGAACGGAATTCATCCGCTTCTCCGGCGTGGTAAATCCACGCACC
+ATCAGCGGTAGCAACTCTGTTCCCTCGACACAGGTGGCGGATGCGCGGATTGAATATGTC
+GGGAACGGCTATATTAACGAAGCGCAAAATATGGGCTGGCTGCAACGTTTCTTCCTTAAT
+TTGTCGCCGATGTAAGTGTTTAAAGCTCTTGCAGGAATCGTTCTGGCACTGGTTGCCACT
+CTGGCGCACGCCGAGCGTATCCGGGATCTGACCAGTGTCCAGGGAGTACGGGAAAACTCG
+CTGATCGGCTACGGGCTGGTGGTCGGGCTGGACGGTACGGGCGACCAGACGACCCAGACG
+CCATTTACCACCCAGACGCTGAATAACATGCTGTCACAACTGGGGATTACGGTCCCCACC
+GGCACCAATATGCAGTTGAAAAACGTGGCGGCGGTGATGGTGACGGCGTCGTATCCGCCT
+TTTGCGCGACAGGGACAAACGATCGATGTCGTCGTTTCCTCAATGGGGAACGCTAAAAGT
+CTGCGTGGCGGGACGTTATTAATGACGCCGTTAAAAGGGGTGGACAGCCAGGTGTATGCT
+CTGGCGCAGGGCAATATTCTGGTCGGCGGCGCGGGCGCTTCCGCAGGCGGCAGTAGCGTG
+CAGGTTAACCAGCTTAATGGCGGGCGCATCACTAATGGCGCGATTATCGAACGCGAGTTG
+CCGACTCAGTTCGGCGCTGGCAACACCATTAATCTGCAATTGAACGACGAAGATTTTACG
+ATGGCGCAGCAAATTACCGACGCCATCAACCGCGCCCGCGGTTACGGCAGCGCCACTGCG
+CTTGATGCGCGAACGGTACAGGTACGCGTGCCCAGCGGCAACAGCTCGCAGGTGCGTTTT
+CTGGCGGACATTCAAAATATGGAAGTCAACGTGACGCCGCAGGATGCAAAAGTCGTGATC
+AACTCGCGTACCGGTTCGGTGGTCATGAATCGGGAAGTCACGCTGGATAGCTGCGCTGTG
+GCGCAGGGCAATTTGTCAGTGACAGTCAATCGCCAACTCAACGTCAACCAGCCGAATACG
+CCATTTGGCGGCGGGCAGACCGTGGTGACGCCACAGACTCAGATAGATTTGCGTCAGAGC
+GGCGGATCGCTACAGAGCGTGCGTTCCAGCGCCAATCTGAACAGCGTAGTGCGCGCGCTG
+AATGCGCTTGGCGCGACGCCGATGGATCTGATGTCGATTTTGCAGTCCATGCAGAGCGCG
+GGCTGTCTACGCGCCAAACTGGAAATCATCTGAATGATCGGAGACGGTAAATTGCTGGCC
+AGCGCGGCCTGGGATGCGCAATCTCTGAACGAACTGAAAGCGAAAGCGGGCCAGGACCCG
+GCGGCGAATATCCGTCCTGTGGCCCGTCAGGTGGAAGGGATGTTTGTGCAGATGATGCTG
+AAAAGTATGCGCGAGGCTTTACCCAAAGATGGTTTATTCAGCAGCGATCAGACGCGTCTG
+TATACCAGCATGTATGACCAGCAGATCGCCCAGCAGATGACCGCCGGTAAGGGATTGGGG
+CTGGCGGATATGATGGTTAAACAGATGACGGGCGGGCAGACGATGCCTGCAGATGATGCG
+CCGCAAGTACCGCTTAAATTCTCCCTGGAGACGGTAAACAGCTATCAAAATCAGGCGCTG
+ACCCAACTGGTGCGCAAAGCCATACCGAAAACGCCGGACAGCAGCGATGCGCCGCTCTCC
+GGCGACAGTAAAGACTTTCTGGCCCGGCTTTCGCTCCCGGCGAGGCTGGCCAGCGAACAA
+AGCGGGGTGCCGCATCATCTGATTCTGGCGCAGGCGGCGCTGGAGTCCGGCTGGGGGCAG
+CGGCAAATCCTGCGGGAGAATGGCGAACCCAGCTATAACGTATTTGGCGTGAAAGCGACC
+GCCAGTTGGAAAGGGCCGGTGACGGAAATCACCACCACTGAATACGAAAATGGCGAAGCG
+AAAAAAGTGAAAGCGAAATTCCGCGTCTATAGCTCGTATCTGGAGGCGTTATCGGATTAT
+GTCGCGCTGTTAACGCGTAACCCACGCTACGCTGCCGTGACCACTGCCGCCACGGCAGAG
+CAGGGCGCAGTGGCTCTGCAAAACGCCGGATACGCCACTGACCCGAATTACGCGCGTAAA
+TTGGCCAGCATGATTCAGCAGTTGAAAGCGATGAGTGAAAAGGTCAGCAAAACCTACAGC
+GCGAATCTCGACAATCTCTTTTAAATGTCCAGCTTGATTAATCACGCCATGAGCGGACTT
+AACGCCGCGCAGGCCGCGTTAAATACGGTCAGTAATAACATCAACAATTATAACGTTGCG
+GGTTATACCCGGCAGACAACTATTCTGGCGCAGGCAAACAGTACGTTAGGGGCTGGCGGC
+TGGATAGGTAATGGCGTTTACGTTTCAGGCGTACAGCGCGAATATGATGCGTTTATCACT
+AATCAGCTACGCGGCGCGCAAAACCAGAGCAGCGGCTTAACCACGCGCTATGAACAAATG
+TCGAAAATCGACAACCTGCTGGCCGATAAATCCAGCTCACTGTCTGGCTCGCTGCAGAGT
+TTTTTTACCAGCCTGCAAACGTTAGTCAGTAATGCGGAAGATCCTGCGGCGCGTCAGGCG
+CTGATTGGTAAAGCGGAAGGGCTGGTAAACCAGTTCAAAACCACCGATCAGTATCTGCGC
+GATCAGGATAAACAGGTCAATATCGCGATTGGCTCCAGCGTGGCGCAAATCAACAATTAC
+GCGAAGCAGATAGCTAACCTGAACGATCAAATCTCCCGTATGACGGGCGTAGGCGCGGGC
+GCATCGCCGAACGACCTGCTCGATCAACGTGATCAGTTGGTTAGCGAGCTTAACAAGATC
+GTTGGCGTCGAGGTGAGTGTACAGGACGGCGGCACCTATAACCTGACGATGGCCAATGGC
+TATACGCTGGTGCAGGGGTCGACGGCGCGTCAGTTGGCGGCGGTTCCCTCCAGCGCCGAC
+CCGACGCGAACGACTGTCGCTTATGTCGATGAGGCCGCCGGTAACATCGAAATTCCGGAA
+AAGTTGCTGAACACCGGTTCGCTCGGCGGGCTACTGACGTTCCGTTCTCAGGATCTGGAT
+CAGACTCGTAATACGCTGGGCCAGTTGGCGTTGGCGTTTGCCGATGCGTTTAACGCGCAG
+CATACCAAAGGTTATGACGCCGACGGCAATAAAGGGAAAGACTTCTTTAGCATTGGCTCG
+CCGGTGGTATATAGCAACAGTAATAATGCCGATAAAACGGTATCGCTAACCGCTAAGGTG
+GTCGACAGCACGAAGGTTCAGGCGACGGATTATAAGATTGTTTTTGACGGTACAGACTGG
+CAGGTTACTCGCACTGCGGATAACACCACCTTCACGGCAACAAAAGATGCTGACGGAAAA
+CTGGAGATTGACGGTCTGAAAGTGACGGTAGGGACTGGCGCACAGAAAAACGACAGTTTT
+CTTCTCAAGCCGGTCAGCAATGCTATCGTCGACATGAACGTTAAAGTGACAAATGAAGCC
+GAGATTGCGATGGCGTCTGAGTCAAAACTCGATCCTGATGTGGATACCGGCGACAGCGAT
+AACCGCAATGGTCAGGCATTGCTGGACTTACAAAACAGCAATGTAGTGGGCGGCAACAAA
+ACCTTTAACGATGCTTACGCCACGTTGGTCAGCGATGTGGGTAACAAAACGTCAACGCTG
+AAAACCAGCAGCACCACGCAGGCGAATGTGGTTAAACAGCTTTATAAACAGCAACAGTCG
+GTTTCCGGCGTTAACCTCGACGAAGAGTACGGCAATTTGCAGCGTTATCAGCAGTATTAT
+CTGGCGAATGCGCAAGTATTGCAGACCGCGAATGCGCTGTTTGATGCGTTATTGAATATT
+CGCTAAATGCGTATCAGTACCCAGATGATGTACGAACAAAATATGAGCGGCATCACTAAT
+TCTCAGGCCGAATGGATGAAGCTGGGCGAGCAGATGTCTACCGGTAAGCGCGTTACCAAC
+CCATCTGACGATCCGATCGCCGCGTCGCAGGCGGTAGTACTCTTTCAGGCGCAGGCGCAG
+AATAGCCAGTACGCCCTGGCGCGTACGTTTGCCACCCAAAAAGTGTCGCTGGAAGAAAGC
+GTACTCAGTCAGGTGACGACGGCGATTCAAACCGCGCAGGAAAAAATCGTCTATGCCGGA
+AACGGCACGTTAAGCGACGATGACCGCGCGTCGCTGGCGACGGATTTACAGGGGATCCGC
+GATCAGCTGATGAACCTGGCAAACAGCACTGACGGCAATGGTCGCTATATCTTTGCCGGG
+TATAAAACGGAAGCGGCGCCATTCGACCAGGCGACAGGTGGTTATCATGGCGGCGAGAAA
+AGTGTTACCCAGCAGGTGGATTCCGCACGCACGATGGTAATTGGCCATACGGGAGCGCAA
+ATTTTTAATAGCATCACCAGCAATGCGGTGCCGGAACCGGATGGCTCGGACTCCGAAAAG
+AATCTGTTTGTCATGCTCGATACGGCAATTGCCGCGCTCAAGACCCCGGTGGAAGGCAAT
+GACGTGGAAAAAGAAAAAGCCGCTGCCGCCATTGATAAAACCAATCGCGGCTTAAAAAAT
+TCGCTTAATAACGTCCTGACCGTTCGTGCGGAACTGGGAACGCAACTGAGCGAACTCAGT
+ACGCTGGATTCACTGGGAAGCGACCGTGCGCTGGGACAGAAGCTACAGATGAGCAACCTG
+GTAGATGTGGACTGGAACTCGGTCATTTCCTCCTACGTCATGCAACAGGCGGCATTACAG
+GCGTCCTATAAAACGTTTACCGACATGCAGGGAATGTCGCTTTTCCAGTTGAACCGGTAA
+atggagataattttttatcacccgacatttaacgccgcctggtgggtaaatgcgctggag
+aaggctctcccacatgcgcgcgttcgtgaatggaaggtcggtgataacaaccccgcagac
+tatgcgcttgtatggcagcccccggttgaaatgctggccggaagacgcttaaaagccgtc
+tttgtgctgggcgcgggggtggatgcaattctgagtaaattaaatgcgcatccggaaatg
+ctggacgcctccattcctctattccgtctggaagataccggaatgggcctgcaaatgcag
+gagtatgccgccagccaggtattacactggttccgtcgtttcgatgattatcaggcgctg
+aaaaatcaggcgctatggaaaccgttgccggaatatacccgcgaagagtttagcgtcggt
+atcataggcgcaggggtactgggcgcaaaagtggcagaaagtctacaggcgtgggggttc
+ccgttacgttgctggagtcgtagccgcaaatcctggcctggcgtggaaagttatgtaggg
+cgtgaagaactgcgcgctttcctgaaccagacgcgggtgctgattaatctgctgccgaat
+acggcccaaacggtaggaattattaatagcgaattgttggatcaattgccggatggcgct
+tacgtgctgaatctcgcgcgcggcgttcatgttcaggaggcggatctgctggctgcgctt
+gatagcggtaagctaaaaggcgcgatgttggatgtctttagccaggaaccgttaccgcag
+gaaagtccattatggcgccatccgcgagtcgccatgacgccgcacattgcggcagtcacc
+cgtccggcggaagccatcgattatattagccgcaccattacccagctggagaagggagag
+ccggtgacggggcaggtggatcgggcgagaggatattgaATGTCCGTAATCAAGAAAAAT
+ATCCCTGCCATAGGCCTGTGTATCTGCGCTTTTTTTATCCATTCTGCGGTAGGGCAACAA
+ACGGTACAGGGCGGCGTTATCCATTTTCGCGGCGCGATTGTTGAGCCACTGTGCGATATT
+TCTACTCACGCCGAAAATATTGATTTAACCTGCCTACGCGAAGGTAAAAAGCAAATGCAC
+CGGATAGACCTTCGGCAGGCATCTGGATTACCGCAGGATATTCAGTCCATTGCGACGGTA
+CGGCTGCATTATCTCGATGCGCAAAAAAGCCTGGCGGTGATGAATATTGAGTACCGTTAA
+ATGGCAAACCATCGTGGCGGTTCCGGTAATTTTGCGGAAGACCGCGAAAGAGCATCAGAA
+GCAGGTCGTAAAAGTGGTCAGCACAGCGGGGGCAATTTTAAGAATGACCCGCAGCGTGCA
+TCCGAAGCAGGCAAAAAAGGGGGCAAAAGCAGTAACCGTAATCGCTAGATGGTAATGTCC
+GCACCAGGACACATTGTTTACAGTAGTTACAACACCCTGTACGGACATTCTCTCTCCGGT
+GGTGGTCTTGTCATCTTAAAAGCTCTCATCATTTCCCTTACTGTCCATACCCATGACGCC
+ATATGTGGTGCGCGTAGCCGTGTGTGGCGTCGTTTCAAAAAGCAAGCTAAGGCTTACAAG
+GAAGCCAACCCTCAGATGTGTGTGCGCATAATCGCGTTCAAGAGAACGCGGGTGATGTAT
+ACCTACAACTCAAGGTGCTATCCATGGGAAGACAAAAAGCAGTGAATGAAACGAATTTTC
+CTTACCTGCGCGGCGTTGTTGTTCAGCAGTCAGGCGTTGGCCGATGAGTGTGCCAGCGCC
+AGTACGCAGCTGGAAATGAATCGCTGCGCCGCCGCGCAATACCAGGCGGCAGATAAAAAG
+CTGAACGAAACCTATCAAAGCGCGATTAAGCGTGCGCAACCGCCGCAGCGTGAGCTATTG
+CAAAAAGCGCAGGTGGCATGGATTGCCCTGCGCGACGCCGATTGCGCGCTGATTCGCTCA
+GGTACGGAGGGCGGCAGCGTTCAACCCATGATCGCCAGCCAGTGCCTGACCGATAAAACG
+AACGAACGCGAAGCGTTTTTAGCCTCGCTGCTGCAATGTGAAGAGGGTGATTTGAGCTGC
+CCACTGCCGCCAGCCGGTTAAgtgcgtatattcgcggtgagcataatggtgattaccctg
+agcggctgcggcagtattatcagcagaacgatccccggacaaggacacggcaaccagtat
+taccctggcgtgcagtgggatatgcgtgattccgcatggcgctatatcactatcctcgat
+ctgcccttctcactgatcttcgatacactgctactgccgctcgatattcaccacgggcct
+tatgagtaaATGTGCCAACGTGCGATCGCCAATATTGATATCAGCAAAGAGTATGACGAA
+AGCATGGGCAGTAACGATGTGCATTATCAGTCGTTTGCTCGTATGGCGGATTTCTTTGGT
+CGTGATATGCAGGCGCATCGCCACGACCAGTTTTTTCAAATGCACTTTCTTGATACCGGG
+CAGATTGAGCTACAGCTCGACGATCATCGCTATTCGGTGCAGGCGCCGCTATTTGTGCTA
+ACGCCGCCCTCGGTGCCGCATGCTTTTATTACCGAATCGGATAGCGATGGTCATGTTCTG
+ACGGTACGCGAAGAGCTGGTTTGGCCGCTGCTGGAAGTGCTTTATCCCGGCACCAGAGAG
+GCCTTCGGCCTGCCGGGAATCTGCCTGTCGCTGGCGGATAAACTCAACGAGCTGGCGGCG
+CTCAAACATTACTGGCAGCTAATTGAGCGGGAGTCCACGGAACAACTGGCTGGCTGCGAA
+CATACCTTGGTACTACTGGCGCAGGCGGTATTTACCTTGCTGTTGCGTAATGCGAAGCTG
+GACGATCATGCCGCAACCGGGATGCGCGGTGAACTGAAACTTTTTCAGCGCTTTACCCTG
+TTAATTGACAACCACTTCCATCAGCACTGGACGGTGCCCGATTATGCCTGTGAGTTGCAT
+ATTACCGAATCTCGTTTGACCGATATTTGCCGACGTTTTGCTAATCGCCCGCCTAAACGC
+CTGATTTTTGATCGGCAATTACGCGAGGCGAAACGACTGCTGCTTTTTTCCGACAATGCT
+GTCAACGAGATCGCCTGGCAATTAGGTTTTAAAGATCCGGCTTATTTCGCCCGTTTCTTT
+AATCGCCTTGCTGGCTGTTCTCCTTCGCAGTTTCGCCAACGTGAAGTTCCTTCTTTTCTC
+AACTAAATGGGACGCACACCGGATTACAAAGCCGCCTTTGGCTGCGCTCTGGGCGCTAAC
+CCAGCCTTCTACGGCCAGTTTGAGCAGAACGCCCGTAACTGGTACACCCGTATTCAGGAG
+ACCGGCCTGTACTTTAACCATGCAATCGTCAACCCGCCCATTGACCGCCACAAACCTGCC
+GACGAAGTGAAAGACGTCTATATCAAGCTGGAGAAAGAGACGGACGCCGGGATTATTGTC
+AGCGGGGCGAAAGTTGTCGCCACTAACTCCGCCCTGACTCACTACAACATGATTGGTTTC
+GGCTCAGCCCAGGTGATGGGCGAAAACCCGGATTTTGCTCTGATGTTTGTCGCGCCAATG
+GATGCCGAAGGCGTAAAACTTATTTCGCGCGCCTCGTATGAAATGGTCGCGGGCGCGACG
+GGCTCGCCGTTTGATTATCCCCTCTCCAGCCGTTTTGATGAAAACGATGCCATTCTGGTG
+ATGGACAAGGTGCTGATCCCGTGGGAAAACGTATTAATTTACCGTGATTTCGATCGTTGT
+CGTCGCTGGACGATGGAAGGCGGCTTTGCCCGTATGTATCCACTGCAAGCCTGTGTTCGT
+CTGGCGGTAAAACTTGATTTCATTACCGCGCTGCTGAAAAAATCGCTCGAATGTACGGGT
+ACCGTAGAGTTCCGGGGCGTGCAGGCCGATCTCGGCGAAGTCGTGGCCTGGCGCAATATG
+TTCTGGGCATTGAGCGATTCTATGTGTTCTGAAGCAACCCCGTGGGTAAACGGCGCCTGG
+CTACCGGACCACGCCGCGCTGCAAACCTATCGTGTGATGGCCCCAATGGCCTACGCGAAA
+ATTAAAAATATTATTGAACGTAACGTTACCAGCGGCCTGATTTACCTGCCTTCCAGCGCC
+CGCGATCTGAATAATCCGCAAATCGACCAGTACCTGGCGAAATACGTACGCGGCTCTAAC
+GGAATGGACCATGTTGAACGTATCAAAATTCTTAAATTGATGTGGGATGCCATCGGCAGC
+GAGTTTGGCGGTCGCCATGAGCTGTACGAGATTAACTACTCGGGCAGCCAGGATGAAATT
+CGTCTGCAGTGTCTGCGTCAGGCCCAGAGCTCCGGCAATATGGATAAGATGATGGCAATG
+GTCGATCGCTGCCTCTCCGAATACGATCAGAATGGCTGGACGGTTTCGCATTTGCACAAT
+AACGACGACATCAATCAACTGGATAAGCTGCTGAAATAAATGCAAGTAGATGAACAACGT
+CTGCGTTTTCGCGATGCGATGGCAAGTCTGGCGGCAGCGGTCAACATCGTAACCACGGCG
+GGTCACGCCGGACGCTGCGGTATCACCGCAACAGCGGTTTGCTCAGTCACTGATACGCCG
+CCCTCCGTGATGGTATGTATTAATGCCAATAGCGCCATGAACCCCGTTTTTCAGGGCAAC
+GGCAGGCTGTGCATTAATGTACTTAACCATGAGCAGGAGCTGATGGCGCGCCACTTTGCC
+GGTATGACGGGGATGGCGATGGAGGAGCGTTTTCACCAGCCATGTTGGCAAAACGGGCCG
+CTGGGCCAGCCGGTACTTAACGGCGCGCTGGCCAGTCTTGAAGGCGAGATCAGCGAGGTA
+CAAACCATTGGCACGCATCTGGTGTATCTGGTGGCGATCAAAAATATTATTCTTAGCCAG
+GAGGGGCATGGCCTGATTTATTTCAAACGCCGTTTTCATCCGGTCAGACTTGAGATGGAA
+GCGCCTGTTTAAATGAAGGGTACTGTTTTCGCCGTTGCGTTAAACCATCGCAGCCAGCTT
+GATGCCTGGCAAGAGGCTTTCTCTCAGCCTCCCTATAATGCGCCGCCTAAAACCGCAGTG
+TGGTTCATCAAGCCGCGTAATACGGTGATTCGTCACGGCGAACCCATTCCTTATCCGCAG
+GGAGAAAAGGTACTGAGCGGCGCGACAGTGGCGCTCATTGTGGGGAAAACCGCCAGCCGG
+ATACGCCCTGAAGCGGCGGCGGACTATATCGCCGGGTATGCGCTGGCTAACGAGGTCAGC
+CTGCCGGAAGAGAGCTTTTATCGCCCGGCGATTAAAGCGAAATGTCGCGATGGCTTTTGC
+CCGCTGGGTGAAATGGCGCCGCTGAGTGATGTGGATAATCTCACCATTATCACTGAAATC
+AACGGACGAGAAGCGGACCACTGGAATACTGCCGATTTACAGCGTAGCGCCGCACAACTG
+CTTAGCGCGTTAAGTGAGTTCGCTACACTTAACCCTGGCGATGCGATCTTACTTGGTACG
+CCGCAGAATCGCGTTGCGCTGCGTCCCGGCGATCGGGTGCGTATTCTGGCGAAAGGTTTA
+CCCGCGCTGGAAAATCCGGTTGTCGCAGAAGATGAATTCGCCCGCCACCAGACGTTTACG
+TGGCCGCTGTCAGCGACGGGAACGTTATTTGCGCTGGGGTTGAACTACGCCGATCACGCC
+AGCGAGCTGGCATTTACGCCGCCGAAAGAGCCGCTGGTATTTATCAAAGCGCCAAACACC
+TTTACCGAACATCACCAAACGTCGGTGCGCCCGAACAACGTCGAATATATGCACTACGAA
+GCCGAGCTGGTCGTGGTGATTGGCAAAACGGCGCGTAAGGTGAGCGAAGCCGAAGCCATG
+GAGTATGTGGCCGGTTACACCGTCTGTAACGACTACGCGATCCGCGACTATCTGGAAAAC
+TACTACCGTCCGAATCTGCGGGTAAAAAGCCGCGACGGCCTGACGCCGATAGGCCCGTGG
+ATTGTGGATAAAGAGGCGGTTTCTGATCCGCACAACCTGACGTTACGCACCTTTGTCAAC
+GGTGAGCTGCGGCAGGAAGGGACGACCGCCGATCTGATCTTCAGCATCCCGTTCCTGATT
+TCTTATCTGAGCGAATTTATGACGTTGCAACCGGGCGACATGATTGCCACCGGTACGCCG
+AAAGGGCTGTCCGATGTGGTGCCGGGGGATGAAGTTGTCGTTGAAGTAGAAGGCGTGGGT
+CGCCTGGTTAACCGAATCGTCAGTGAGGAGAGCGCAAAATGAATGAAAAATGCTTTCAAA
+GACGCGTTAAAAGCGGGGCGCCCGCAAATCGGTTTGTGGCTGGGGCTTGCCAACAGTTAC
+AGCGCTGAACTGTTAGCGGGCGCCGGCTTCGACTGGCTACTGATTGACGGTGAACACGCG
+CCAAACAACGTGCAGACGGTGTTGACCCAGTTGCAGGCGATTGCGCCTTATCCCAGCCAG
+CCGGTGGTGCGTCCGTCATGGAACGATCCGGTACAGATTAAGCAACTGCTCGACGTCGGC
+GCGCAAACGCTGCTGATACCGATGGTGCAGAATGCCGATGAAGCGCGAAACGCCGTGGCG
+GCTACGCGTTATCCGCCTGCCGGTATTCGCGGCGTGGGCAGCGCGCTGGCGCGGGCATCG
+CGCTGGAATCGCATTCCGGACTATCTCCACCAGGCCAACGACGCCATGTGCGTACTGGTG
+CAGATTGAAACGCGTGAGGCGATGAGCAATCTGGCGTCAATTCTCGACGTGGATGGCATT
+GACGGCGTGTTTATTGGCCCGGCGGATCTCAGCGCCGATATGGGCTTTGCCGGCAATCCG
+CAGCACCCGGAAGTGCAGGCGGCGATTGAGAACGCCATCGTGCAGATACGCGCGGCGGGG
+AAAGCGCCGGGGATTCTGATGGCCAATGAAGCACTGGCGAAACGTTATCTGGAACTGGGG
+GCGCTATTTGTCGCCGTCGGCGTTGACACCACGCTGCTGGCGCGCGGAGCGGAGGCGCTG
+GCGGCGCGCTTTGGCGCAGAAAAAAAACTGTCCGGTGCGTCCGGCGTCTATTAAATGCAT
+GATTCATTAACCATCGCCTTGCTTCAGGCGCGCGAAGCGGCAATGACCTATTTCCGCCCC
+ATCGTTAAAAGCCACAATCTGACCGACCAGCAATGGCGCATTGTGCGAATCCTGGCCGAT
+AGCCCCTCTATGGATTTTCACGAGCTGGCCTTTCGTACCTGTATTTTGCGTCCAAGTCTG
+ACCGGAATATTGACGCGCATGGAGCGAGACGGACTGGTGTTGCGACTCAAGCCGGTTAAC
+GATCAGCGTAAGTTATATGTCATGTTGACGGAGCAGGGACAAACGTTGTACGCCCGTGCC
+CGGAGCGAGGTAGAAGAGGCTTATCGAAAAATTGAGGCCGATTTCACGCCCGAAAAAACA
+CAGCAATTGATGCTGCTGCTGGACGATCTTATTGCTCTGGGGCGCCAGCATCCTGATAGC
+GAAGCGGAAGCATAGATGAGCGACACATCATCTGCACTTCCGGAAAGCCCCGAGTCTGTC
+GGTTCGCACAACGCGCTCAGCACGGGTCAACAAACCGTCATAAATAAACTGTTCCGCCGA
+CTGATCGTATTTTTATTCGTGTTGTTTATCTTCTCGTTTTTAGACCGTATCAACATCGGT
+TTTGCCGGGTTGACGATGGGGCAGGATCTGGGGTTAAGCGCCACCATGTTTGGTCTTGCC
+ACGACGCTGTTTTACGCCACCTACGTCATTTTCGGCATTCCCAGCAACGTGATGTTGAGC
+ATCGTCGGCGCCCGCCGCTGGATTGCGACCATTATGGTGCTATGGGGCATTGCATCTACC
+GCCACGATGTTCGCGGTGGGACCGAAAAGCCTGTATGTGCTGCGAATGCTGGTGGGCATT
+ACCGAAGCGGGCTTTTTGCCAGGAATATTGCTCTATTTAACCTACTGGTTCCCGGCATTT
+TTCCGCGCCCGCGCCAACGCATTATTTATGATTGCCATGCCGGCCACTACCGCGTTGGGG
+TCAATTGTCTCCGGCTATATTTTATCGCTGGACGGCATATTCAATCTGCATGGATGGCAG
+TGGTTATTCCTGTTGGAAGGATTTCCGTCAGTTTTGTTAGGCATTATGGTCTGGTTTTAC
+CTGGATGATACCCCGGCAAAAGCCAAATGGCTGACGGCAGAGGATAAAAAATGTTTGCAG
+GAGATGATGGATAATGATCGCCTGACGCTGGTTCAGCCTGAGGGGGCCATCAGCCATAAC
+GCCATGCAGCAGCGTAGCCTGTGGCGCGAAGTATTCACGCCAATTGTACTGATGTATACG
+CTGGCCTATTTTTGCCTTACCAATACGCTTAGCGCCATTAGTATCTGGACGCCGCAAATC
+CTGAAAAGTTTTAATGAAGGCAGCAGCAATATCACCATCGGCCTGCTGGCGGCGATCCCG
+CAGATTTGTACTGTTCTGGGCATGATTTACTGGAGCCGCCATTCGGACAAACATCAGGAG
+CGTAAACACCACACTGCGTTACCGTTCCTGTTTGCCGCCGCGGGCTGGCTGCTGGCGTCG
+GCGACCGACCGTAACCTGATCCAGCTCCTGGGGATCGTGATGGCATCCACGGGTTCCTTT
+AGCGCGATGGCGATCTTCTGGACCACGCCGGATCAGTCGATCAGTTTACGCGCCAGGGCG
+ATAGGCATTGCGGTCATCAATGCCACCGGCAATATTGGCTCCGCGCTCAGCCCGGTTATG
+ATTGGCTGGCTAAAAGATATCACTGGTAGCTTCAATAGCGGACTCTGGTTTGTCGCTTCT
+CTGTTAGTCGTCGGCGCCGCCATTATCTGGCTCATTCCCATGAAAGCATCGCGTCCGCGC
+GCCACCCCTTGAATGGGCAAGTTAGCGTTAGCAGCAAAAATTACCCACGTGCCGTCGATG
+TATCTTTCTGAACTGCCAGGAAAAAATCACGGTTGTCGTCAGGCAGCCATTGATGGGCAT
+ATTGAAATTGGCAAGCGTTGCCGCGAAATGGGCGTTGACACCATTATCGTATTCGACACC
+CACTGGCTGGTGAATAGCGCTTACCACATTAATTGTGCCGACCATTTCCAGGGCGTCTAT
+ACCAGCAACGAATTGCCGCACTTTATTCGCGACATGACCTATGACTATGACGGTAATCCG
+GCGCTCGGCCATCTGATCGCCGACGAGGCGGTCAAACTGGGCGTGCGCGCCAAAGCGCAC
+AACATCCCGAGCCTGAAGCTGGAGTATGGCACGCTGGTGCCGATGCGCTACATGAACAGC
+GACAAGCACTTCAAAGTGGTCTCCATCTCGGCGTTCTGCACTGTGCATGATTTTGCCGAC
+AGCCGCAAACTGGGCGAAGCCATTCTCAAGGCGATTGAGAAATATGACGGTACCGTAGCG
+GTATTCGCCAGTGGTTCTCTGTCGCACCGTTTTATTGACGACCAACGGGCGGAAGAGGGG
+ATGAACAGCTACACCCGCGAGTTCGATCATCAAATGGACGAGCGCGTGGTCAAGCTGTGG
+CGCGAAGGCAAATTCAAGGAGTTTTGCACCATGTTGCCGGAGTACGCCGACTACTGCTAC
+GGCGAAGGCAACATGCACGACACGGTCATGCTACTGGGAATGCTGGGGTGGGACAAATAC
+GACGGCAAGGTGGAGTTCATCACCGACCTGTTCGCCAGCTCCGGTACCGGCCAGGTAAAC
+GCTGTTTTCCCGCTGCCTGCGTAAATGAAGAAAATAAATCATTGGATTAACGGCAAAAAC
+GTTGCAGGTAACGACTACTTCCAGACCACTAACCCGGCGACCGGTGATGTGCTGGCGGAA
+GTAGCCTCCGGCGGTGAAGCAGAAGTGAACCAGGCTGTCGCGGCGGCAAAAGAGGCGTTC
+CCGAAATGGGCCAACCTGCCGATGAAAGAGCGCGCGCGCCTGATGCGCCGCCTTGGCGAC
+CTGATTGACCAGCATGTGCCGGAAATCGCGGCGATGGAAACCGCCGACACCGGCCTGCCT
+ATTCACCAGACTAAAACGTGCTGAGTGCTGATCCCGCGCGCCTCGCATAACTTCGAATTC
+TTCGCCGAAGTGTGCCAGCAGATGAACGGCAAGACCTATCCGGTTGACGATAAAATGCTC
+AATTATACGCTGGTGCAGCCCGTCGGCGTCTGCGCGCTGGTGTCGCCGTGGAACGTGCCG
+TTTATGACCGCGACTTGGAAAGTTGCGCCGTGCCTGGCGCTGGGTAACACCGCGGTGCTC
+AAAATGTCCGAGCTGTCGCCGCTGACTGCCGACAGGCTGGGCGAGCTGGCACTGGAGGCA
+GGAATTCCGGCAGGCGTGCTGAACGTGGTGCAGGGCTACGGCGCGACGGCGGGCGATGCG
+CTGGTACGCCACCATGACGTGCGTGCGGTGTCGTTTACCGGCGGTACCGCCACCGGTCGC
+AATATCATGAAAAATGCCGGGCTGAAAAAATACTCGATGGAGCTGGGCGGCAAATCGCCG
+GTGCTGATTTTTGAAGACGCCGACATTGAGCGCGCGCTGGACGCCGCGCTGTTCACCATC
+TTCTCGATCAACGGCGAACGCTGCACCGCTGGGTCGCGCATCTTTATCCAGCAGAGCATT
+TACCCTGAGTTCGTGAAGCGCTTTGCCGAACGCGCGAATCGCCTGCGTGTCGGCGATCCG
+ACCGACCCGAACACCCAGGTCGGCGCGCTGATTAGCCAACAGCACTGGGAGAAAGTCTCC
+GGTTATATCCGCCTCGGCATTGAAGAGGGGGCAACGCTGCTGGCGGGCGGTGCGGAAAAA
+CCCACTGACCTGCCTGCGCATCTGAAAGGCGGTAACTTCCTGCGCCCAACCGTGCTGGCC
+GATGTCGACAACCGTATGCGCGTTGCGCAGGAAGAGATCTTTGGGCCGGTCGCCTGCCTG
+CTGCCATTCAAAGACGAAGCGGAAGGGTTACGTTTGGCGAACGATGTGGAATACGGTCTG
+GCCTCTTATATCTGGACCCAGGACGTGAGCAAAGTGTTGCGCCTGGCGCGTGGGATTGAA
+GCCGGCATGGTCTTCGTCAACACCCAGAACGTCCGCGACCTGCGCCAGCCGTTCGGCGGC
+GTGAAAGCCTCCGGTACCGGGCGCGAAGGCGGCGAATATAGCTTCGAAGTGTTTGCGGAA
+ATGAAAAACGTCTGCATCTCAATGGGCGACCATCCTATCCCAAAATGGGGAGTTTGAATG
+CCGCACTTTATTGCTGAATGTACTGAAAATATTCGCGAGCAGGCTGATTTACCAAGCCTG
+TTCAGCAAGGTAAACGAGGCGCTGGCCGCCACCGGGATTTTCCCCATCGGCGGTATCCGC
+AGTCGCGCCCACTGGCTGGATACCTGGCAGATGGCTGACGGTAAGCATGATTACGCGTTT
+GTGCATATGACGCTGAAAATCGGCGCCGGGCGCAGCCTGGAGAGCCGTCAGGAAGTCGGC
+GAAATGCTGTTTGGGCTGATTAAAGCCCACTTCGCCGACCTGATGGAGAACCGCTATCTG
+GCGCTGTCGTTTGAGATTGCCGAGTTACATCCAACGCTCAATTACAAACAAAACAACGTA
+CACGCGTTATTTAAATAGATGCTCGATAAACAGACCCATACCCTGATCGCTCAGCGACTT
+AATCAGGCTGAAAAACAGCGTGAACAGATTCGCGCAGTGTCGCTGGATTATCCCAACATC
+ACTATTGAAGATGCCTATGCCGTACAGCGTGAATGGGTCAATATCAAGATTGCCGAAGGG
+CGCACGCTCAAAGGCCACAAAATCGGCCTGACCTCAAAAGCGATGCAGGCCAGCTCGCAA
+ATCAGCGAACCGGATTACGGCGCGCTGCTTGACGATATGTTCTTCCATGACGGCGGAGAT
+ATCCCCACCGACCGTTTTATCGTCCCGCGTATTGAAGTGGAGCTGGCGTTCGTGCTGGCG
+AAACCGCTGCGCGGCCCTCACTGCACGCTGTTCGACGTCTACAACGCCACGGATTATGTG
+ATTCCGGCGCTGGAACTGATTGACGCCCGCAGCCACAACATCGACCCGGAAACCCAGCGC
+CCGCGCAAAGTGTTCGACACCATTTCCGACAACGCCGCCAACGCCGGGGTGATCCTCGGT
+GGTCGCCCCATCAAACCAGACGAGCTGGATCTGCGCTGGATCTCCGCGCTGCTCTATCGC
+AACGGCGTGATCGAAGAAACCGGCGTCGCCGCAGGCGTGCTGAATCATCCGGCCAACGGC
+GTGGCGTGGCTGGCGAACAAGCTTGCCCCCTACGATGTCCAGCTTGAAGCCGGGCAGATC
+ATCCTCGGCGGCTCGTTCACCCGCCCGGTGCCGGCGCGCAAGGGCGACACCTTCCATGTC
+GATTACGGCAACATGGGCGCGATCAGTTGCCGGTTTGTGTAAATGAGCTCTGTACCCGCG
+CCGCGTGAATATTTTCTTGACTCTATCCGCGCATGGCTGATGTTGTTAGGGATTCCCTTT
+CATATCTCGTTGATCTATTCCACTCACAGTTGGCATGTCAATAGCGCCGCGCCATCGTGG
+TGGCTAACCCTGTTTAACGATTTTATCCACGCTTTTCGTATGCAGGTGTTTTTTGTTATT
+TCTGGTTATTTTTCGTACATGTTATTTTTACGTTATCCATTAAAACACTGGTGGAAAGTA
+CGGGTAGAACGTGTGGGTATTCCCATGCTTACCGCAATCCCTTTGCTTACCTTGCCGCAA
+TTTATCCTGTTGCAATATGTCAAAGAGAAAACAGAGAACTGGCCTACACTCTCTGCCTAT
+GAAAAATATAATACGTTAGCGTGGGAACTCATTTCACATCTGTGGTTTTTACTGGTGCTG
+GTGATATTAACCACCGTCAGCATCGGGATTTTTACCTGGTTCCAAAAAAGGCAGGAAACA
+AGCAAGCCTCGTCCCGCCGCTATTTCGCTGGCCAAACTTTCGCTTATTTTTTTCCTGCTG
+GGGGTGGCGTACGCTGCTATCAGGCGCATTATATTCATCGTATATCCGGCAATCCTCAGT
+GACGGCATGTTCAATTTTATTGTGATGCAAACGCTATTTTATGTGCCGTTTTTTATTCTC
+GGCGCGTTGGCCTTCATTCACCCCGATCTGAAAGCGCGCTTCACCACGCCCTCACGCGGA
+TGCACTTTAGGCGCTGCCGTTGCTTTTATCGCGTATCTGCTGAATCAACGTTATGGGAGC
+GGCGACGCCTGGATGTACGAAACCGAATCCGTGATTACGATGGTAATGGGGCTATGGATG
+GTGAACGTGGTATTTTCACTGGGGCATCGCTTGTTAAACTTTCAGTCCGCGCGTGTCACC
+TATTTCGTGAATGCTTCGCTGTTTATTTATCTGGTGCATCATCCCTTAACGCTTTTCTTT
+GGCGCGTATATTACACCGCATATCTCCTCCAACCTGATCGGGTTCTTGTGCGGGCTGATA
+TTTGTTATGGGTATTGCGTTAATTCTGTATGAAATTCATTTACGCATCCCGCTCCTGAAA
+TTTCTCTTTTCAGGTAAACCGCCGGTAAAACAAGAAAGCCGCGCCGCGATCGGGTAGATG
+AAACATAAACGACAAATGATGAAAATGCGTTGGTTGGGCGCAGCTATTATGTTAACGCTC
+TACGCATCATCGAGCTGGGCGTTCAGTATTGATGACGTGGCAAAACAAGCTCAATCTTTA
+GCCGGGAAAGGCTATGAGGCGCCTAAAAGCAACTTGCCCTCCGTTTTCCGCGACATGAAA
+TATGCGGATTATCAGCAGATCCAGTTTAACAGCGATAAAGCCTACTGGAACAACTTAAAG
+ACCCCTTTTAAGCTCGAATTTTACCATCAGGGGATGTACTTCGATACGCCGGTCAAGATT
+AACGAAGTGACGGCGACGACGGTCAAAAGAATCAAATACAGCCCGGATTACTTCAATTTT
+GGCAATGTTCAGCACGATAAAGACACGGTAAAAGATTTAGGCTTCGCCGGGTTCAAAGTC
+CTGTACCCCATTAACAGTAAAGATAAGAACGACGAAATCGTCAGTATGCTTGGCGCCAGC
+TATTTCCGCGTTATCGGCGCAGGCCAGGTGTATGGCTTATCTGCGCGCGGCCTGGCGATT
+GATACCGCCTTACCATCTGGTGAAGAGTTTCCCCGCTTTCGCGAGTTCTGGATTGAGCGT
+CCAAAACCCACCGATAAGCGTTTGACCGTCTATGCATTACTGGATTCTCCGCGCGCGACC
+GGCGCTTACCGTTTTGTGATCATTCCTGGCCGCGATACCGTGGTGGACGTGCAGTCAAAA
+GTCTATCTGCGCGATAAGGTGGGCAAGCTGGGCGTTGCGCCATTAACCAGTATGTTCCTG
+TTTGGGCCAAACCAGCCGTCGCCGACGACCAACTATCGTCCGGAATTGCATGACTCGAAC
+GGCTTATCCATTCATGCGGGTAATGGCGAGTGGATTTGGCGTCCGCTGAACAATCCAAAA
+CACCTCGCTGTGAGCAGCTATGCGATGGAAAACCCTCAGGGATTCGGCCTGTTGCAGCGT
+GGTCGCGAGTTCTCGCGCTTTGAAGATTTAGACGATCGCTATGACCTGCGTCCAAGCGCC
+TGGATTACCCCGAAAGGCGACTGGGGCAAAGGTAAGGTTGAACTGGTTGAAATTCCGACC
+AATGATGAAACCAACGATAACATCGTCGCTTACTGGACTCCGGATCAACTGCCGGAACCG
+GGTAAAGAGATGAACTTCAAGTACACTCTGACCTTCAGCCGCGATGAAGATAAACTTCAT
+GCGCCGGATAATGCCTGGGTGCTGCAAACACGCCGCTCAACGGGCGACGTTAAACAGTCG
+AATCTGATTCGCCAGCCCGACGGCACTATTGCCTTTGTGGTGGATTTCGTTGGCGCCGAC
+ATGAAAAAACTGCCGCCGGATACGCCCGTCGCTGCACAAACCAGCATTGGCGATAACGGT
+GAAATCGTTGACAGTAATGTACGCTATAACCCAGTCACTAAAGGCTGGCGTTTAATGCTG
+CGCGTGAAAGTCAAAGACGCGAAGAAAACCACGGAAATGCGTGCCGCATTGGTGAATGCC
+GATCAGACGCTAAGTGAAACCTGGAGCTACCAGTTACCTGCCAATGAATAAatgaataaa
+acaactgagtatattgacgcactgctgctttctgaacgtgagaaagcggcattgccgaaa
+actgacatccgcgccgtgcatcaggcgctggatgccgagcatcggacttactcgcgagaa
+gacgattcaccgcagggttccgtaaaagcccgccttgaacacgcctggccggattcattg
+gcgaaggggcagttaattaaagatgatgaagggcgcgatcagttgcaggctatgccaaaa
+gcgacgcgctcttcgatgtttcctgatccctggcgaaccaacccggttggccgtttctgg
+gatcgcctgcgtgggcgggatgtaacgccgcgctatgtttctcgtctgacaaaagaagag
+caggcgagtgagcaaaaatggcgtaccgtcggcactatacgccgctatattttgttaatt
+ttgactctggcgcaaaccgtcgtcgcgacctggtatatgaagaccattctgccctatcag
+ggatgggcgctcatcaatcctatggatatggtggggcaggatatttgggtctcctttatg
+cagctcctgccctacatgctgcaaaccggtatcctgattttgtttgccgtgctgttctgc
+tgggtgtctgccggattctggacggcgctgatgggcttcctgcaactgcttatcgggcgc
+gataagtacagtatctccgcgtctacggttggcgatgagcccctcaatccggaacaccag
+acggcgctgatcatgcctatctgtaatgaagacgttagccgcgttttcgccggtctgcgc
+gcgacctgggagtccgttaaagccacaggcaacgccgcgcattttgacgtctatatcctt
+agcgatagttataacccggatatctgcgtggcggagcaaaaggcgtggatggagctcatc
+gcggaagtgcagggcgaaggccaaattttttaccgtcgccgccgccgccgtatgaaacgc
+aaaagcggcaatattgacgatttttgccgccgctggggcaatcagtacagctatatggtg
+gtgctggacgcggactcagtgatgagcggcgagtgtctgagcgggctggtgcgcctgatg
+gaagcgaaccctaacgccgggattatccagtcttcgccgaaagcgtcggggatggatact
+ctgtatgcccgctgccaacagttcgcgacccgtgtttatggaccgctgtttaccgccggg
+ctgcacttctggcagttgggggagtcgcactactgggggcacaatgccattatccgcgtg
+aagccgtttatcgagcactgcgctctggcgccgctgccgggagaaggttcgttcgccgga
+tcgattctttcccacgactttgtggaggcggcgctaatgcgtcgggcagggtggggcgtc
+tggattgcctacgatctccccggctcctatgaagagctgccgccaaacctgctggatgag
+cttaaacgcgaccgccgctggtgtcacggcaacctgatgaactttcgtctgttcctggtg
+aaaggaatgcacccggtgcatcgcgccgtgttcctgaccggggtaatgtcatacctgtcc
+gcgccgttatggtttatgttcctcgcgctttctaccgcgctgcaggtcgttcatgcgtta
+acagagccgcaatatttccttcagccgcgccagctttttccggtctggccgcagtggcgt
+ccggaactggcaatcgcgctgtttgcgtcaacgatggtgctgctgttcctgccgaagctg
+ctcagtattatgctgatctggtgtaaaggcaccaaagagtatggcggtttctggcgcgtt
+acgctgtcgctattgctggaagtgctgttctccgtgttgctggcgccggtgcgtatgctg
+tttcataccgtgtttgtggtcagcgcgttcctcggctgggaagtggtctggaactcaccg
+caacgcgacgatgattctacgccgtggggagaagcctttatgcgtcacggctctcaactg
+ctgctggggctggtctgggcggtgggtatggcgtggctggatttacgctttctgttctgg
+ctggcgccgattgtcttttcgctgattctgtcgccatttgtttcggtgatctccagtcgt
+tcaacggtaggattacgcaccaaacgctggaagctgttcctgatcccggaagagtattcg
+ccgcctcaggtgttggtcgataccgataaatatctggagatgaatcgccgccgtattctg
+gacgatggctttatgcatgcggtatttaacccgtcgcttaatgcgctggcgaccgcgatg
+gccaccgcgcgtcaccgcgccagtaaggtgctggaaatagcccgcgatcgtcatgtggag
+caggcgctaaacgaaacgccggagaaactgaaccgcgatcggcgtctggttttgctcagc
+gatccggtgacgatggcgcgtttacactatcgggtctggaatgcgccagagagatactct
+tcctgggtaaaccattatcagtctctcgtcctgaatccgcaggcgttgcagggacgaaca
+tcgtcagcgggataaatgtcgcgcgtctcgcaggcgaggaacctgggtaaatattttctt
+ctcatcgataacatgttagtggtgctgggttttttcgtcgtcttcccgctcatctctatt
+cgctttgtcgatcaaatggggtgggctgccgtaatggtagggatcgcgctcggcctgcgt
+cagtttattcaacaaggtctgggcatttttggcggcgccatcgccgatcgctttggcgcg
+aaaccgatgattgtcaccggtatgctgatgcgcgccgcaggctttgccaccatgggtatc
+gcgcatgagccctggctcttgtggttttcctgctttctttccggtctcggcggtacgctt
+ttcgacccgccgcgttcagcgctggtggtcaaattaattcgtccggagcaacggggccgc
+ttcttctctctgttgatgatgcaggacagcgcgggcgcggtgattggcgcgctgctggga
+agctggttgctacaatacgattttcgcctggtctgcgcgacgggcgctattttgttcata
+ttatgcgcccttttcaacgcatggctgcttccggcctggaagctatcaacggccagaacg
+ccggtgcgtgaaggaatgcgccgcgtcatgagcaataaaaggtttgtcacctacgtgctg
+acgctggcgggctactatatgctggcggtacaggtcatgttaatgctgccgattatggta
+aacgatatcgccggttcgcctgctgccgtgaaatggatgtacgctattgaggcgtgtctc
+tcgctgacgttgctctacccgattgcccgctggagcgaaaagcgttttcggctggagcat
+cggctgatggccggtttgctcgtcatgtcgctgagcatgctccccatcgggatggtgggc
+aatttacagcagctttttacgcttatttgcgctttctacatcggctcggttatcgccgaa
+ccggcgcgcgaaacgctcagcgcgtcgcccgcggacgcgagggcgcggggaagctatatg
+ggctttagccgtctgggattagccattggcggcgcgattagttatatcggcggcggctgg
+ttgtttgatatgggtaaagcgcttgcgcagcctgaactaccgtggatgatgctcggtatt
+atcggctttatcacctttttggctttaggctggcaatttagtcataagcgcacgccgcgc
+cggatgctggaacccggcgcctgaatgaccatgtatgccacgctggaagaagctatcgat
+gcagcccgggaagaatttctggctgaccatccaggcctcgaacaagacgaagcgaatgtg
+cagcagttcaacgttcagaaatatgtactgcaggatggggacatcatgtggcaggtcgaa
+tttttcgccgatgaaggtgaagatggcgaatgtctgccgatgctgagtggtgaagccgca
+cagagcgtgtttgacggcgattatgatgagatagagatccgccaggaatggcaggaagag
+aatactttgcatgaatgggatgaaggggaattccagcttgaacccccgcttgataccgag
+gaaggccgtactgcggcagacgaatgggatgagcgttaaATGTCACTATTAGCCAGGCTG
+GAACAAAGTGTACACGAAAACGGTGGGCTGATTGTCTCATGCCAACCGGTACCAGGCAGC
+CCTATGGATAAACCTGAAATTGTGGCTGCAATGGCACAGGCAGCGGCTTCGGCGGGTGCG
+GTCGCTGTGCGCATTGAAGGCATTGAGAATCTGCGGACTGTTCGTCCCCATCTTTCTGTT
+CCTATTATTGGGATAATTAAACGTGACCTTACAGGGTCGCCAGTCCGTATCACTCCATAT
+TTACAGGATGTTGACGCCCTGGCGCAGGCAGGTGCCGATATTATCGCTTTTGATGCCTCA
+TTCCGCTCTCGCCCGGTTGATATTGATAGTTTACTGACACGTATTCGCCTGCATGGATTA
+CTGGCGATGGCAGACTGTTCAACCGTGAATGAAGGCATAAGTTGCCATCAGAAAGGAATC
+GAATTCATTGGTACAACACTGTCTGGCTATACCGGTCCCATCACGCCGGTTGAGCCAGAT
+TTGGCAATGGTGACACAACTGAGTCATGCAGGTTGTCGTGTTATTGCCGAGGGGCGCTAT
+AACACGCCTGCACTGGCGGCCAATGCTATTGAGCATGGTGCCTGGGCAGTTACCGTTGGT
+TCCGCTATCACCCGTATCGAGCATATCTGTCAGTGGTTCAGTCACGCAGTAAAACGCTGA
+ATGAAAAATTTTAAGAAAATGATGACGCTAATGGCGCTATGTTTATCAGTTGCTATCACC
+ACATCAGGATATGCAACCACGCTTCCTGATATACCAGAACCACTGAAAAATGGTACTGGC
+GCTATTGATAATAATGGCGTGATTTATGTCGGCTTAGGTACCGCAGGGACATCCTGGTAT
+AAAATTGATCTTAAAAAGCAACATAAAGACTGGGAGCGTATAAAGTCGTTTCCTGGTGGA
+GCTCGTGAGCAATCCGTGTCGGTATTTTTAAATGATAAGCTGTATGTTTTTGGTGGCGTA
+GGGAAAAAAAACAGTGAATCACCGTTGCAGGTTTATAGCGATGTGTACAAATACTCACCG
+GTGAAAAATACATGGCAAAAAGTTGATACTATATCTCCAGTTGGATTAACAGGGCATACG
+GGAGTAAAATTAAACGAAACGATGGTACTTATTACCGGAGGGGTTAATGAGCATATCTTT
+GATAAGTATTTTATTGATATAGCGGCTGCGGATGAAAGTGAAAAAAATAAAGTCATCTAT
+AATTATTTTAATAAACCTGCCAAAGATTATTTTTTTAATAAAATCGTATTTATCTACAAT
+GCTAAAGAGAACACATGGAAGAATGCCGGTGAGCTGCCAGGCGCGGGGACGGCAGGATCG
+TCATCGGTAATGGAAAATAATTTCTTGATGCTGATTAATGGTGAGCTCAAACCGGGTTTA
+CGTACCGATGTGATTTACCGCGCCATGTGGGATAACGATAAGCTAACATGGTTGAAGAAC
+AGCCAGTTACCGCCATCGCCTGGAGAACAACAGCAGGAAGGGTTGGCCGGAGCATTTTCG
+GGCTATAGCCACGGTGTCCTGCTTGTCGGTGGTGGCGCGAATTTTCCGGGAGCAAAACAA
+AATTATACTAATGGAAAGTTTTATTCCCACGAAGGGATAAATAAAAAATGGCGAGATGAA
+GTCTATGGTTTGATTAATGGCCATTGGCAATATATGGGTAAAATGAAACAACCTCTCGGC
+TATGGTGTATCAGTAAGTTATGGTGATGAAGTTTTCCTTATTGGTGGTGAAAATGCTAAA
+GGGAAACCTGTTTCGTCTGTAACCTCCTTTACCATGCGTGATGGTAATTTATTAATAAAA
+TAAGTGATAGCAAAATTCTTCCCGTGGTATAGCGAGATAACACGTCCACAAAAAAATGCT
+TTATTTTCAGCATGGCTGGGTTACGTTTTTGATGGCTTCGACTTTATGCTGATTTTCTAC
+ATTATGTATCTGATCAAGGCTGACTTAGGATTGACAGATATGGAGGGCGCATTCCTTGCC
+ACAGCGGCCTTTATTGGGCGACCATTTGGCGGGGCGCTATTTGGTCTGCTGGCAGACAAA
+TTTGGCCGTAAGCCGTTAATGATGTGGTCGATAGTTGCCTATTCTGTAGGTACAGGGTTA
+AGTGGCCTGGCTTCCGGTGTAATTATGCTGACGCTTAGTCGTTTTATTGTCGGTATGGGG
+ATGGCGGGGAAGTATGCTTGCGCTTCTACTTATGCCGTGGAAAGTTGGCCAAAGCATTTA
+AAATCTAAAGCGAGCGCATTTCTGGTTTCAGGTTTCGGTATTGGTAACATCATAGCAGCC
+TATTTTATGCCGTCATTTGCCGAAGCGTATGGTTGGCGTGCTGCTTTTTTTGTCGGTTTG
+CTACCCGTTCTTTTAGTAATCTACATCCGGGCCAGGGCTCCTGAATCTAAAGAGTGGGAA
+GAAGCCAAACTCAGTGGTCTCGGAAAGCATTCACAAAGTGCCTGGTCAGTTTTCTCTTTG
+TCAATGAAAGGGCTATTTAATCGAGCTCAATTTCCACTGACATTATGTGTATTTATTGTT
+CTGTTCTCTATTTTCGGCGCAAACTGGCCGATCTTTGGTCTACTGCCTACATATTTGGCG
+GGAGAGGGCTTTGATACGGGCGTGGTCTCTAATTTAATGACGGCGGCGGCATTCGGCACT
+GTATTGGGAAATATCGTTTGGGGTCTGTGCGCAGATAGAATTGGTTTGAAGAAAACGTTC
+AGCATTGGTCTTCTCATGTCCTTTTTATTCATTTTCCCGTTATTCAGAATTCCGCAAGAT
+AATTATTTACTGCTGGGCGCATGTTTATTCGGTTTAATGGCGACTAACGTAGGTGTTGGC
+GGGCTGGTTCCCAAATTTCTCTACGACTACTTTCCTCTTGAGGTTCGTGGTTTGGGTACC
+GGGCTTATTTATAATCTTGCTGCGACATCAGGCACATTCAATTCAATGGCGGCGACCTGG
+CTTGGAATAACAATGGGGCTAGGCGCTGCGCTAACGTTCATTGTTGCTTTCTGGACCGCA
+ACAATTCTACTCATTATTGGCCTATCCATTCCGGATAGACTAAAAGCACGTCGTGAAAGG
+TTTCAGTCAACAAAAGAATTTTAAATGAAAAAGTATCTTGCTTTCGCCGTTACGCTGCTG
+GGTATGGGTAAAGTCATCGCCTGTACTACCCTTTTGGTAGGCAATCAGGCTTCGGCTGAC
+GGCTCCTTTATTATCGCGCGCAACGAGGATGGCTCGGCAAATAACGCCAAGCATAAGGTT
+ATTCATCCCGTCGCGTTTCATCAACAAGGCGAGTATAAAGCACATCGCAACAATTTTAGC
+TGGCCGCTTCCGGAGACAGCGATGCGCTATACGGCGATTCATGACTTTGATACTAACGAT
+AACGCCATGGGTGAAGCCGGTTTCAATTCGGCGGGCGTCGGAATGAGCGCAACGGAAACC
+ATTTACAACGGCAGAGCGGCGCTGGCTGCCGATCCTTACGTGACAAAAACGGGAATCACG
+GAAGACGCCATTGAGTCCGTGATCCTGCCAGTGGCGCAATCGGCGCGTCAGGGCGCCAAA
+TTACTGGGAGATATTATTGAACAAAAAGGCGCGGGCGAAGGTTTCGGCGTCGCGTTTATT
+GATAGCAAAGAGATATGGTATCTGGAGACGGGAAGCGGACATCAATGGCTGGCAGTACGA
+CTTCCGGCAGATAGCTATTTCGTTTCCGCCAATCAGGGACGTTTACGCCATTACGATCCG
+AATGATAACGCGAATTATATGGCGTCACCAACGTTAGTAAGCTTTGCGAAAAAGCAGGGA
+TTATATGATCCGGCCCGCGGCGAATTCGACTTTCATCAAGCCTATTCGCAGGATAACAAA
+AACGATACCACCTATAATTATCCGCGCGTCTGGACGCTACAACACCAGTTTAATCCGCAT
+CTGGATACGGTCGTTAGCGAAGGGGAAACATTTTCTGTTTTTTTAACGCCAATAACGAAG
+ATCAGCGTGGCGGCAGTAAAAAACGCGTTACGCAATCACTATCAGGGAACGTCGCACGAC
+CCTTATGCCAGTCATAATCCACAAGAACCATGGCGACCTATATCCGTTTTTCGTACCCAG
+GAGTCACATATTTTACAGGTCAGACCGAAATTACCGCAGGCTATCGGCAACGTAGAATAC
+ATCGCCTATGGAATGCCATCTCTTAGCGTCTATCTCCCCTATTACCAGGGGATGCGTCAT
+TATCAACCCGGAGATGATAAAGGAACCGATCGGGCGAGCAACGACTCTACCTACTGGACA
+TTCCGCACGCTGCAAACACTGGTTATGCAAGACTACAATACGTTTGCGCCAGATGTGCAA
+CATGCCTGGAAAACATTTGAACAGCAAACAGCTAAGCAACAGTATAAGATGGAGCAGAGC
+TATCTGAGATTATATGCGTCGCATCCGAAAGAAGCACAACGCTTACTGCAAAATTTTGAA
+GATAAAACGATGCAAAATGCGCAGACGCTCGCCCGTCGCCTGACCAATAATATTATTACG
+ACAATGACTTACCGCACAGATATGAAATATCACTTTTCAAGTACGCAGCCATAAATGGGA
+AGACAAAAAGCAGTGATCAAAGCTCGTCGTGAAGCAAAGCGTGTGTTGAGACGAGATTCG
+CGTAGTCATAAGCAACGTGAAGAAGAATCGGTCACGTCACTGGTACAGATGGGCGGAGTA
+GAAGCCATTGGCATGGCGCGCGATAGTCGCGATACCTCTCCTGTTAAGGCGCGAAATGAA
+GCACAGGCGCATTATCTGAACGCTATCGACAGTAAACAGCTTATTTTTGCGACCGGCGAA
+GCCGGCTGCGGAAAAACATGGATCAGTGCGGCAAAGGCGGCAGAAGCATTGATTCATAAG
+GACGTCGAGAGGATCATTGTGACGCGTCCGGTATTGCAGGCTGATGAAGATCTTGGTTTT
+TTGCCCGGTGATATCGCTGAAAAATTCGCGCCTTATTTTCGTCCCGTCTACGATGTCCTG
+CTTAAACGGTTGGGCGCGTCCTTTATGCAATATTGTTTGCGCCCGGAAATCGGTAAGGTA
+GAAATTGCCCCGTTCGCCTATATGCGTGGGCGTACTTTTGAAAATGCGGTCGTGATCCTC
+GACGAGGCGCAAAATGTGACTGCGGCGCAAATGAAAATGTTTTTGACGCGATTAGGCGAA
+AATGTCACGGTCATTGTCAATGGCGATATTACGCAATGCGACCTGCCGCGCGGTGTGCGT
+TCCGGGTTGAGTGATGCGTTGGAACGCTTTGAAGAAGATGAAATGGTGGGGATTGTGCAT
+TTCAACAAAGACGACTGCGTGCGCTCGGCGCTTTGTCAGCGAACGCTCCACGCATACAGC
+TAAATGGGAACCACCACGATGGGGGTTAAGCTGGACGACGCCACGCGCGAACGGATCAAA
+ATGGCCGCGTCGCGTATCGATCGCACGCCGCACTGGTTAATAAAACAGGCAATCTTTAGC
+TATCTGGACAAGCTGGAAAATAGCGATACGCTACCGGAGCTACCTGCGCTGTTTGCCGGC
+GCGGCAAATGAAAGCGAGGAGCCGGTCGCGCCGCAGGATGAGCCGCATCAGCCCTTTCTG
+GAGTTTGCCGAACAGATTCTTCCCCAATCCGTCTCTCGCGCCGCCATCACCGCCGCCTGG
+CGCCGCCCGGAAACCGATGCGGTGTCAATGCTAATGGAACAGGCGCGCCTGTCGCCGCCT
+GTCGCTGAGCAGGCGCATAAACTGGCGTATCAACTGGCGGAGAAATTGCGCAATCAAAAA
+TCCGCCAGCGGTCGCGCGGGTATGGTGCAAGGCCTGTTGCAGGAGTTTTCCCTCTCTTCG
+CAAGAAGGCGTAGCGCTGATGTGTCTGGCGGAAGCGCTGCTGCGTATTCCCGACAAAGCT
+ACGCGCGATGCGTTAATTCGCGACAAAATCAGTAATGGCAACTGGCAGTCGCATATTGGC
+CGTAGCCCGTCGCTGTTTGTAAACGCCGCCACCTGGGGGCTGCTCTTTACCGGCCGACTG
+GTCTCAACGCATAACGAAGCCAATCTTTCGCGCTCGCTGAACCGCATTATCGGCAAGAGC
+GGCGAACCGTTAATCCGCAAAGGCGTCGACATGGCGATGCGTTTAATGGGCGAGCAGTTC
+GTGACTGGCGAAACCATTGCTCAGGCGCTGGCGAATGCCCGAAAACTGGAAGAGAAAGGG
+TTCCGCTATTCTTACGATATGCTGGGCGAAGCCGCGTTAACCGCCGCCGATGCGCAGGCC
+TATATGGTCTCTTACCAGCAAGCGATTCATGCCATCGGCAAAGCGTCTAACGGTCGCGGT
+ATTTACGAAGGGCCAGGCATCTCGATTAAGCTGTCCGCCCTGCATCCACGCTATAGTCGC
+GCGCAATACGATCGGGTAATGGAGGAGCTTTATCCGCGCCTGAAATCCCTGACGCTGCTG
+GCGCGCCAGTATGATATCGGTCTCAATATCGACGCCGAAGAGGCGGATCGTCTGGAGATC
+TCGCTTGATCTGCTGGAAAAACTCTGCTTCGAACCCGAACTGGCGGGCTGGAACGGCATT
+GGCTTTGTGATTCAGGCTTACCAGAAACGCTGCCCGCTGGTCATTGATTATTTAGTCGAT
+CTGGCCTCCCGTAGCCGCCGTCGGCTGATGATTCGTCTGGTGAAAGGCGCCTACTGGGAT
+AGCGAGATCAAACGCGCGCAAATGGAAGGGCTGGAGGGCTATCCAGTTTATACCCGCAAA
+GTGTATACCGATGTCTCTTATCTGGCCTGCGCGAAAAAACTGCTCGCCGTCCCTAATCTG
+ATCTACCCGCAGTTCGCGACCCATAACGCTCACACACTGGCGGCGATTTATCATCTGGCC
+GGGCAAAATTACTATCCGGGTCAGTACGAATTCCAGTGCCTGCACGGCATGGGAGAACCG
+CTGTATGAACAGGTCACCGGTAAAGTGGGGGACGGAAAACTTAACCGTCCCTGCCGTATT
+TACGCGCCGGTGGGAACACACGAAACCCTGCTGGCCTATCTGGTACGACGCCTGCTGGAA
+AACGGCGCCAACACCTCTTTTGTCAACCGCATCGCCGATGCCACCCTACCGCTCGATGAA
+CTGGTGGCCGACCCGGTCGAGGCCGTGGAAAAACTGGCGCAGCAGGAAGGTCAGGCTGGC
+ATACCGCATCCAAAAATTCCGCTGCCGCGCGATCTGTACGGCGAAGGTCGGATAAACTCC
+GCCGGACTTGATTTAGCGAATGAACATCGCCTCGCCTCGCTTTCTTCTGCCCTGTTAAGC
+AACGCCATGCAGAAATGGCAGGCCAAACCTGTGCTGGAACAACCGGTGGCCGACGGTGAG
+ATGACGCCGGTTATCAACCCGGCGGAACCGAAAGATATTGTTGGCTGGGGACGCGAAGCG
+ACAGAAAGCGAGGTTGAACAGGCGTTGCAAAACGCGGTCAATCAGGCGCCGGTTTGGTTT
+GCGACGCCGCCGCAAGAACGCGCCGCTATTTTGCAGCGGGCGGCGGTATTGATGGAAGAC
+CAAATGCAGCAGTTGATTGGCCTGTTGGTGCGTGAAGCGGGGAAAACGTTCAGCAACGCC
+ATTGCCGAAGTGCGCGAAGCGGTAGACTTCCTCCATTATTATGCCGGTCAAGTGCGTGAC
+GATTTCGATAACGAAACGCATCGCCCGTTAGGGCCGGTGGTCTGTATCAGTCCGTGGAAC
+TTTCCGCTGGCCATTTTCACTGGCCAAATCGCCGCCGCGCTGGCGGCAGGTAACAGCGTT
+CTGGCGAAACCGGCAGAGCAGACATCGCTGATTGCCGCCCAGGGCATTGCCATTTTGCTG
+GAAGCGGGCGTACCGCCGGGCGTCGTGCAACTGTTGCCGGGACGGGGAGAAACCGTCGGC
+GCCCAGCTTACCGCCGATGCGCGTGTACGCGGCGTGATGTTTACCGGTTCCACGGAGGTC
+GCGACGTTGTTGCAGCGCAACATCGCCACGCGTCTTGACGCCCAGGGGCGCCCTATTCCG
+TTGATTGCGGAAACCGGCGGTATGAACGCTATGATTGTCGACTCTTCCGCGCTCACCGAG
+CAGGTGGTCGTGGATGTGCTGGCTTCCGCCTTCGACAGCGCCGGACAACGCTGTTCCGCG
+CTCCGCGTGCTGTGTTTGCAGGACGATATCGCCGAACATACGCTGAAAATGTTACGCGGC
+GCGATGGCGGAGTGTCGGATGGGGAATCCAGGCCGTCTGACGACCGATATCGGGCCGGTG
+ATCGATAGCGAGGCCAAAGCCAACATTGAACGTCATATCCAGACGATGCGCGCCAAAGGC
+CGCCCGGTTTTCCAGGCCGCGCGTGAAAACAGCGATGACGCGCAGGAATGGCAGACCGGT
+ACGTTTGTTATGCCCACGCTTATTGAGCTGGAAAACTTCGCAGAACTGGAAAAAGAGGTC
+TTCGGGCCCGTGCTGCACGTCGTGCGTTATAACCGTAACCAACTGGCGGAGCTTATCGAA
+CAGATTAACGCTTCCGGCTACGGGCTAACGCTGGGCGTACATACCCGTATTGATGAAACC
+ATTGCGCAAGTCACCGGTTCCGCCCATGTCGGCAACCTGTACGTTAACCGTAATATGGTG
+GGCGCGGTCGTCGGCGTCCAGCCGTTTGGCGGCGAAGGCCTGTCCGGCACCGGGCCAAAA
+GCGGGAGGGCCGCTCTATCTCTACCGCCTGCTGGCACACCGCCCGCCCAATGCGCTCAAT
+ACGACGCTGACTCGTCAGGATGCGCGTTACCCGGTGGATGCGCAGCTTAAAACCACGCTA
+CTCGCGCCGTTGACCGCTCTGACGCAATGGGCGGCGGATCGCCCGGCGCTACAGACGCTC
+TGCCGACAATTCGCCGATCTGGCGCAGGCCGGCACGCAGCGCCTGCTACCGGGGCCGACC
+GGCGAGCGTAATACCTGGACGCTGTTGCCGCGTGAACGGGTGTTATGCCTGGCTGATGAT
+GAACAGGACGCGTTGACGCAGCTTGCCGCCGTTCTCGCCGTCGGCAGTCAGGCGCTATGG
+TCAGACGACGCCTTCCACCGCGATCTGGCGAAACGTCTCCCCGCCGCCGTCGCGGCGCGT
+GTCCAGTTTGCGAAAGCGGAAACGCTGATGGCGCAGCCGTTTGACGCGGTGATTTTCCAC
+GGCGACTCCGACAAGCTGCGAACCGTGTGCGAAGCCGTCGCCGCCCGCGAAGGCGCGATA
+GTGTCGGTACAGGGGTTCGCCCGCGGCGAAAGCAATATGCTGCTGGAACGGCTCTATATT
+GAACGTTCGCTGAGCGTAAACACTGCCGCCGCTGGCGGTAATGCCAGCCTGATGACAATT
+GGCTAAATGGCTATTAGCACACCGATGTTGGTGACATTCTGTGTCTATATTTTTGGCATG
+ATATTGATTGGGTTTATCGCCTGGCGCTCAACCAAAAACTTTGATGACTATATTCTTGGC
+GGTCGCAGCCTGGGGCCGTTTGTTACGGCTTTATCAGCCGGCGCGTCGGATATGAGCGGC
+TGGCTGTTAATGGGGCTGCCTGGCGCTATCTTTCTGTCGGGGATCTCTGAAAGCTGGATC
+GCCATTGGCCTGACGTTAGGCGCATGGATTAACTGGAAGCTGGTGGCCGGGCGCCTGCGC
+GTGCATACCGAATTTAACAATAACGCGCTCACGCTGCCGGACTATTTTACCGGTCGGTTT
+GAGGATAAGAGCCGAGTCCTGCGTATTATTTCCGCGCTGGTCATTCTGCTGTTTTTCACT
+ATCTATTGCGCATCAGGTATTGTCGCTGGGGCACGACTGTTCGAAAGCACCTTCGGTATG
+AGCTATGAAACCGCACTGTGGGCGGGGGCCGCGGCAACCATTATTTATACCTTTATCGGC
+GGGTTTCTTGCCGTTAGCTGGACGGATACCGTTCAGGCCAGCCTGATGATTTTTGCGTTA
+ATCCTGACGCCGGTGATGGTTATTGTCGGCGTAGGCGGTTTTAGCGAGTCGCTGGAAGTG
+ATCAAGCAAAAGAGCATCGAGAATGTCGACATGCTCAAGGGGCTGAATTTTGTCGCTATT
+ATTTCTCTGATGGGCTGGGGGCTGGGTTACTTCGGTCAGCCGCATATCCTGGCGCGCTTT
+ATGGCGGCGGATTCCCATCACAGTATTGTTCATGCGCGTCGTATCAGTATGACCTGGATG
+ATTCTGTGTCTGGCGGGCGCGGTGGCGGTGGGCTTCTTTGGCATTGCGTACTTTAACAAT
+AACCCCGCGCTGGCCGGGGCGGTGAACCAAAACTCAGAACGCGTATTTATTGAACTGGCG
+CAGATCCTGTTTAACCCGTGGATTGCCGGTGTTCTGCTGTCTGCTATCCTGGCGGCGGTG
+ATGTCGACGTTGAGCTGTCAGTTGCTGGTATGCTCCAGCGCGATTACGGAAGATTTATAT
+AAGGCTTTTCTGCGTAAAAGCGCCAGCCAGCAAGAGCTGGTATGGGTAGGGCGAGTGATG
+GTGCTGGTGGTAGCGCTGATCGCCATTGCGCTGGCGGCGAATCCTGATAACCGTGTGCTG
+GGGCTGGTGAGCTACGCCTGGGCTGGATTCGGCGCGGCATTTGGACCTGTTGTCCTGTTT
+TCTGTGATGTGGTCGCGTATGACACGTAACGGCGCGCTGGCGGGAATGATTATTGGCGCG
+GTGACGGTTATCGTCTGGAAACAATATGGCTGGCTGGATCTGTATGAGATTATCCCTGGC
+TTCATTTTCGGCAGCCTGGGGATCGTAATCTTTAGCCTGCTTGGCAAAGCGCCGACAGCA
+ACGATGCAGGAACGCTTTGCAAAAGCGGACGCGCATTATCATTCCGCGCCGCCGTCGAAG
+CTACAGGCGGAATAAATGGCGGGTAAACTGCGGCGTTGGCTGCGTGAAGCCGCGGTTTTT
+CTGGCGCTCCTCATCGCGATAATGGTGGTCATGGACGTCTGGCGCGCGCCGCAGGCGCCT
+CCGGCGTTTGCCGCGACACCATTACATACGCTGACGGGAGAGTCGACAACTCTGGCGACC
+TTGAGCGAGGAACGCCCCGTACTGCTCTATTTTTGGGCCAGCTGGTGCGGGGTATGCCGC
+TTTACCACGCCTGCGGTCGCTCACCTGGCGGCGGAAGGGGAAAACGTCATGACCGTTGCG
+CTCCGCTCCGGCGGTGATGCTGAGGTTGCCCGCTGGCTGGCGCGCAAGGGCGTTGACTTC
+CCGGTCGTCAATGATGCTAACGGCGCCTTATCCGCTGGCTGGGAAATCAGCGTGACGCCA
+ACGCTGGTGGTGGTTTCACAAGGTCGGGTTGTGTTCACCACCAGCGGCTGGACCAGCTAT
+TGGGGCATGAAGCTTCGGCTGTGGTGGGCAAAAACGTTCTGAATGATGAAAAAAAGCGTC
+GCTATGCTGGCGGTTTGTATGCTGGCGCAAAGCCACCTTGCCATTGCTGCCGGTGCTCCT
+GCGCCTCAAGAGATCAACATTGTTTTACTGGGCACCAAAGGCGGGCCTTCTTTGCTCAAT
+ACAGCCAGACTACCGCAAGCGACGGCGCTCACTATCGGCGATAAGATATGGCTGATAGAT
+GCCGGCTACGGCGCCAGTCTGCAACTGGTGAAAAATGGCATTCCACTGCGCAACATCAAT
+ACTATTTTGCTCACCCATCTGCACAGCGACCACATACTGGATTATCCTTCCTTGCTGATG
+AATGCCTGGGCAAGTGGCCTGAAAGACCATACCATACAGGTTTATGGCCCGCCGGGAACC
+CAGGCGATGACGAAGGCTAGCTGGAAGGTCTTTGACAGGGATATCACGTTACGCATGGAA
+GAAGAGGGGAAACCCGATCCGCGCAACCTGGTTAAGGCGACCGATATCGGCCAGGGCGTC
+ATCTATAAAGATGAACTGGTCACAATAAGCGCGCTGAAAGTGCCTCATTCCCCTTTCCCG
+GACGGTGAAGCGTTTGCTTACCGTTTTGATACTCAGGGTAAGCGAATCGTCTTCTCTGGC
+GATACGTCCTGGTTTCCTCCGCTTGCAACGTTTGCCCAGGGGGCGGATATCCTGGTACAT
+GAGGCGGTACATGTCCCTTCGGTAGCAAAACTGGCTAATAGTATTGGCAACGGAAAAACG
+CTGGCTGAAGCGATTGCGTCGCATCACACCACGATTGAAGATGTCGGTAAGATTGCTCGC
+GAGGCCCACGTGAAAAAACTGGTGTTAAGTCATCTGGTGCCTGCGACGGTTGCGGATGAC
+GTCTGGCAACAGGAAGCCATGAAAAATTACCCGGGCCCTGTCATTGTCGGTCATGACAAT
+ATGACGATAAGCGTACCGTAAATGTCGCAACGCACAGAGAAAAAAATCGGGAAACGTTCG
+CAGGCCACCGGTGCAAAACGGCAGCTTATCTTAACCGCCGCGCTTGCCGTTTTTTCCCAG
+TATGGCATTCATGGCGCGCGTCTTGAACAGGTCGCCGAGCGGGCAGGCGTCTCCAAAACC
+AATCTGCTTTATTATTATCCCTCGAAAGAGGCGCTGTATGTCGCGGTAATGCGACAGATT
+CTGGATGTCTGGTTGGCGCCGCTCAAGGCGTTTCGCGCAGAATTTTCCCCTCTGGAGGCC
+ATCAAAGAGTATATCCGTCTCAAGCTGGAGGTTTCGCGTGATTATCCGCAGGCGTCGCGG
+CTCTTCTGCATGGAGATGCTGGCGGGCGCGCCGCTCTTAATGGATGAACTGACCGGCGAT
+CTAAAAGCGTTGATAGATGAAAAATCCGCGCTGATTGCCGGATGGGTGCACAGCGGGAAA
+CTCGCGCCCGTTTCTCCGCATCATTTGATCTTCATGATTTGGGCCGCCACGCAACATTAC
+GCCGATTTCGCCCCTCAGGTTGAAGCGGTAACCGGCGCGACGCTTCGCGATGAAGCCTTT
+TTCAACCAAACGGTCGAAAGCGTTCAGCGCATTATTATTGAAGGGATTCGCGTGCGTTAA
+ATGGCGAAACAACAACGGATGGGCTGGTGGTTTCTTTGCCTTGCATGTGTCGTGGTAATG
+GTTTGTACCGCGCAACGCATGGCGGGCCTGCACGCCTTGCAGATGCAGGCGACGGCCTCT
+GCTGCGGTGGTCAGCGCTCCCTCCTCGACAGATGACGGCTCGCCGGTCACTCCCTGCGAA
+TTAAGCGCCAAGTCGCTGCTGGCGGCGCCTCCAGTACTCTTTGAAGGTGCTATCCTTGCG
+CTTTATCTACTGCTTTCCTTACTGGCGCCTGTCCGGGTCATGCGCCTGCCGTTTTCGCCT
+CCACGGGCTATTTCGCCGCCCACATTACGGGTACATCTACGATTTTGTGTCTTCCGTGAA
+TGAATGATGATTTTATTCAGGCGGATACTGTTCTGCCTGTTATGGCTTTGGCTGCCCGTC
+TCCTGGGCGGCGGAAAGCGGCTGGCTGCGTTCGCCCGATAACGACCATGCCAGCATACGG
+CTACGTGCCGATACGTCCGCTAACAGTGAGACCCGGCTGTTGCTGGATGTCAAACTGGAA
+AACGGCTGGAAAACCTACTGGCGCGCGCCGGGGGAAGGGGGCGTGGCACCCTCTATCGCC
+TGGAAAGGCGACATGCCTGAGGTAAGCTGGTTCTGGCCAACCCCCTCGCGCTTTGATGTG
+GCGAATATCACCACCCAGGGATATCACGACGAGGTGACCTTTCCGATGATCGTGCGCGGT
+ACGCCGCCGGCGACCTTGCGCGGTGTGTTGACGTTATCAACCTGCAGCAATGTTTGTCTG
+TTGACCGATTACCCCTTTTCCGTGACGCCCACTGTGCAGAATGCCGATTTTGCCCATGAC
+TATGCGCGGGCGATGGGTAAAGTTCCGCTCCGCAGTGGGCTAACGGACTCGCTTGACGTT
+GGCTATCGCCCGGGAGAACTGGTGGTCACTGCTACGCGAGCGGCGGGCTGGTCATCGCCC
+GGGCTCTATCTTGACACCATAGATGACGTCGATTTTGCGAAGCCTCGCCTGCGCGTAGAG
+GGCGACAGGTTACAGGCGACGGTGCCGGTGACGGACAGTTGGGGCGAAAAGGCGCCCGAT
+TTGCGCGACAAATCGCTGACCCTCGTGTTAGCCGATGGCGCTATCGCCCAGGAGAGCACG
+CAAACCATTGGCGCTGCGCCAGCGCAAACGCCGGACAATGCGGCGCTACCTTTCTGGCAA
+GTTGTAATGATGGCGCTAATCGGCGGACTGATTCTTAATTTAATGCCCTGCGTACTGCCT
+GTTCTGGGCATGAAACTTGGCTCTATTTTATTGGTAGAGGAAAAAAGCCGCTCTCACATC
+AGGCGACAATTTTTGGCTTCGGTCGCCGGTATCATTGCGTCATTTATGGCGCTGGCGGCG
+TTTATGACCCTCCTTCGCCTGTCAAACCATGCGCTGGCCTGGGGAGTCCAGTTCCAGAAT
+GCATGGTTTATTGGTTTTATGGCGCTGGTGATGTTGTTGTTTAGCGCCAGCCTGTTCGGG
+CTTTTTGAGTTCAGGCTTCCCTCATCTATGACCACGAAACTGGCCACTTACGGCGGTAAC
+GGTATGTCGGGACATTTCTGGCAGGGGGCGTTCGCCACGCTGCTGGCGACGCCTTGTAGC
+GCGCCGTTTCTGGGCACGGCGGTCGCGGTGGCGCTCACGGCGTCGCTGCCGACGCTGTGG
+GGGCTGTTCCTTGCGCTTGGCCTGGGAATGAGCGCGCCGTGGCTACTGGTCGCGATACGA
+CCAGGGCTTGCGCTACGTTTACCGCGCCCCGGGCGTTGGATGAATGTCCTGCGCAGGATC
+CTCGGTCTGATGATGCTGGGGTCGGCTATCTGGCTGGCGACGTTACTCCTGCCGCATTTC
+GGCTTCACTGCGTCAAAGAGCGCGCAAGACACGGTTCAGTGGCAACCGTTGAGTGAACAG
+GCAATCCAGTCGGCGCTGGCGCAGCATAAGCGGGTATTTGTCGATGTCACTGCGGACTGG
+TGTATTACCTGTAAAGTGAATAAATACAACGTCCTGCAAAAAGAGGATGTGCAGGCCGCC
+TTGCAACAGCCGGATGTTGTGGCGCTGCGGGGAGACTGGACGCTGCCGTCCGATGCCATT
+ACAGATTTTCTGAAAACGCGCGGCCAGGTCGCCGTGCCGTTTAATCAGGTATATGGCCCC
+GGTTTGCCGGAAGGGGAGGCACTGCCCACTTTGCTGACCCGCGATGCGGTATTACAAACG
+TTGAAAAAAGCGAAAGGAATAACCCAATGAATGAAATACATGATTGTTTTACTGCTGGCG
+CTGTTTTCGACGCTGAGCATCGCGCAAGAAACCGCTCCTTTTACGCCGGATCAGGAAAAG
+CAGATTAAAAATCTGATCCATGCGGCGTTGTTTAACGATCCTGCCAGCCCGCGGATAGGC
+GCTAAACACCCTAAGCTGACGCTGGTGAACTTTACGGATTACAACTGCCCGTACTGCAAA
+CAGCTCGATCCGATGCTGGAAAAGATTGTGCAGAAATATCCTGACGTTGCGGTCATTATT
+AAACCGCTGCCATTCAAAGGAGAGAGTTCCATACTGGCGGCGCGTATTGCGCTGACCACC
+TGGCGCGATCATCCGCAACAGTTCCTCGCGCTACATGAAAAACTTATGCAAAAGCGCGGT
+TACCATACGGATGACAGTATTAAACAGGCCCAGCAGAAAGCAGGGGCGACGCCAGTGACG
+CTGGATGAAAAAAGCATGGAAACGATACGCACTAATTTGCAGTTGGCAAGACTGGTCGAC
+GTGCAAGGAACGCCAGCGACGATCATTGGCGACGAGCTGATTCCGGGCGCAGTGCCCTGG
+GATACGCTGGAAGCGGTGGTGAAAGAAAAACTGGCGGCTGCCAATGGCGGGTAAatgatt
+acacattctttcggcatcgttaattattttgtattatttggctacctcctggccatgatg
+ttagtcggtgtctatttttccagacggcaaaaaacagcagacgattattttcgcggtggt
+ggccgggttcctggttgggcggctggggtcagtgtatttgctactacgttaagctcaatt
+acatttatgtcaattcctgccaaagcgtttacttccgactggacgtttatcattggtcag
+tatctggctatcgcaattttaccgctggttttttatttctatattccgttttttcggaaa
+ttgaaagtcacatcagcctatgaatatctcgaagcacggttcgatgtgcgctgccgtctg
+ttcgccagcatgtcatttatgttgtttcatattggacgtatcgccattatcactttcctc
+accgtgctggccttgcgccccttcatcgctatagacccggtgattttggtactgttgatt
+agtgtgatgtgtatcatttatacctggatgggggggaattgaatggaaagtctattaaat
+cgtttatatgacgcgttaggcctggatgcgccagaagatgagccactgcttatcattgat
+gatgggatacaggtttattttaatgaatccgatcatacactggaaatgtgctgtcccttt
+atgccactgcctgacgacactctgactttgcagcattttttacgtcttaactacgccagc
+gccgtcactatcggcgctgatgcagacaatactgctttagtggcgctttatcgcttgccg
+caaaccagtaccgaagaagaggcgctcactggttttgaattattcatttcaaacgtgaag
+caattgaaagagcattatgcataaATGAAATACGACCTTATTATTATCGGCAGCGGTTCG
+GTTGGCGCCGCCGCTGGTTATTACGCCACCCGCGCCGGGCTAAAGGTCCTGATGACCGAT
+GCGCATATGCCGCCTTATCAACAGGGCAGCCACCACGGCGATACCCGTCTTATCCGCCAC
+GCTTATGGTGAAGGCGAAAAATATGTCCCGCTGGTGCTTCGCGCCCAGACGCTTTGGGAT
+GAGCTCTCCACACACAATGAAGAGCCTATTTTTGTCCGCTCCGGCGTCGTCAACCTCGGC
+CCGGCCGATTCCGCTTTCTTAGCCAACGTCGCACGAAGCGCGCAACAGTGGCAATTGAAC
+GTCGAGCGCCTGGACGCGACGGCCCTCATGACGCGCTGGCCGGAAATTCGCGTGCCCGAT
+AATTATATCGGGCTGTTTGAAGCTGACTCCGGTTTCCTGCGCAGCGAATTAGCCATTACC
+ACATGGCTTCGTCTGGCCCGAGAGGCAGGCTGCGCACAGCTATTCAACAGCCCGGTAAGC
+CATATTCACCATGATGATAACGGTGTGACGATAGAGACGAGTGAAGGCTGCTACCACGCC
+AGCAAAGCGCTGATTAGCGCGGGCACCTGGGTCAAAACGCTGGTACCGGAGCTGCCCGTT
+CAGCCCGTACGTAAAGTTTTTGCCTGGTTTAAGGCGGATGGACGTTACAGCACTAAAAAC
+CGCTTTCCGGCCTTTACCGGCGAAATGCCCAACGGCGATCACTATTACGGTTTCCCGGCG
+GAGAACGACGAGTTAAAAATCGGCAAACACAATGGCGGGCAGCGAATACAGGCACCGGAA
+GAGCGCAAGCCCTTTGCCGCCGTTGCCAGCGATGGCGCGGAAGCATTTCCTTTCCTGCGT
+AACGTACTGCCGGGTATCGGCGGTTGTTTACATGGGGCGGCATGTACCTATGATAATTCG
+CCGGACGAGGATTTTATTATCGATACGCTGCCTGGCCATGAGAATACGCTTGTCATCACT
+GGACTCAGCGGACATGGTTTTAAATTCGCCCCGGTGTTAGGAGAAATCGCTGCGGATTTT
+GCGTTGGGAAAAACGCCCTCCTTTGATCTGACGCCGTTCCGGCTTTCCCGTTTTAGCCAA
+TAAatgcaaatacagagcttctatcactcagcttcactaaaaacccaggaggcttttaaa
+agcctacaaaaaaccttatacaacggaatgcagattctctcaggccagggcaaagcgccg
+gctaaagcgcccgacgctcgcccggaaattattgtcctgcgagaacctggcgcgacatgg
+gggaattatctacagcatcagaagacgtctaaccactcgctgcataacctctataactta
+cagcgcgatcttcttaccgtcgcggcaaccgttctgggtaaacaagacccggttctaacg
+tcaatggcaaaccaaatggagttagccaaagttaaagcggaccggccagcaacaaaacaa
+gaagaagctgcggcaaaagcattgaagaaaaatcttatcgaacttattgcagcacgcact
+cagcagcaaaatggcttacctgcaaaagaagctcatcgctttgcggcagtagcgtttaga
+gatgctcaggtcaagcagctcaataaccagccctggcaaaccataaaaaatacactcacg
+cataacgggcatcactataccaacacgcagctccctgccgcagagatgaaaatcggcgca
+aaagatatctttcccagtgcttatgagggaaagggcgtatgcagttgggataccaagaat
+attcatcacgccaataatttgtggatgtccacggtgagtgtgcatgaggacggtaaagat
+aaaacgcttttttgcgggatacgtcatggtgtgctttccccctatcatgaaaaagatccg
+cttctgcgtcaggccggcgctgaaaacaaagccaaagaagtattagctgcggcacttttt
+agtaaacctgagttgcttaacagagccttagagggcgaagcggtaagcctgaaactggta
+tccgtcgggttactcaccgcgtcgaatattttcggcaaagagggaactatggtcgaggat
+caaatgcgcgcatggcaatcgttgacccagccgggaaaaatgattcatttaaaaatccgc
+aataaagatggcgatctacagacggtaaaaataaaaccggacgtcgccgcatttaatgtg
+ggtgttaatgagctggcgctcaagctcggctttggccttaaagcatcagatagctataat
+gccgaagcgctacatcagttattaggcaatgatttacgccctgaagccagaccaggtggc
+tgggttggcgaatggctggcgcaatacccggataattatgaggtcgtcaatacattagcg
+cgccagattaaggatatctggaaaaataaccaacatcataaagatggcggcgaaccctat
+aaactcgcacaacgccttgccatgttagcccatgaaattgacgcggtgcccgcctggaat
+tgtaaaagcggcaaagatcgtacagggatgatggattcagaaatcaagcgagagctcatt
+tctttccatcagacccatatgttaagtgcgcctggtagtcttccggatagcggtggacag
+aaaattttccaaaaagtattactgaatagcggtaacctggagattcagaaacaaaatacg
+ggcggggcgggaaacaaagtaatgaaaaatttatcgccagaggtgctcaatctttcctat
+caaaaacgagttggggatgaaaatatttggcagtcagtaaaaggtatttcttcattaatc
+acatcttgaATGAAACGATATATACTGGCTACCGCGATAGCGTCTCTTGTTGCAGCCCCG
+GCAATGGCGCTGGCCGCTGGCAGCAATATTCTCAGCGTACATATTCTCGATCAGCAAACA
+GGCAAACCAGCGCCCGGCGTGGAGGTGGTACTGGAGCAGAAAAAGGATAACGGATGGACG
+CAATTAAACACCGGGCATACCGACCAGGATGGACGAATTAAAGCACTGTGGCCCGAAAAA
+GCTGCCGCGCCGGGGGATTATCGCGTTATTTTTAAAACCGGCCAGTATTTTGAAAGTAAA
+AAACTGGACACGTTTTTCCCGGAGATTCCCGTCGAGTTTCATATCAGCAAAACGAATGAG
+CACTATCATGTGCCGCTGTTATTAAGTCAGTATGGTTATTCAACCTATCGCGGGAGCTAA
+ATGGCAAAGATTCTGGTGCTCTATTATTCCATGTACGGACACATTGAAACCATGGCGCAC
+GCGGTGGCGGAAGGGGCAAAGAAAGTCGACGGCGCAGAGGTCATTATAAAGCGTGTGCCA
+GAAACAATGCCGCCTGAAATCTTCGCAAAAGCTGGCGGTAAAACGCAAAACGCACCGGTT
+GCCACCCCACAGGAGCTGGCGGATTACGATGCCATTATTTTTGGTACGCCAACCCGGTTT
+GGCAATATGTCAGGCCAGATGCGTACCTTCCTGGACCAAACCGGCGGACTGTGGGCATCC
+GGCGCGCTATACGGCAAGCTCGGCGGCGTGTTCAGTTCTACCGGAACGGGCGGCGGCCAG
+GAGCAGACCATCACCTCGACCTGGACTACGCTTGCCCATCATGGGATGGTGATTGTCCCG
+ATAGGCTATTCCGCACAGGAACTGTTTGACGTCTCCCAGGTTCGCGGCGGTACGCCTTAC
+GGCGCAACGACTATCGCTGGAGGCGACGGTTCACGTCAACCAAGCCAGGAGGAACTCTCT
+ATCGCTCGCTATCAGGGGGAATACGTCGCCGGTCTGGCAGTCAAACTCAACGGCTAAatg
+gagcctcaacccccacgtcttaaacccggaaaaatccttgacactctgggtgctatgcaa
+aaaagcctgacacgtgcctcccagcgtattgcgcaatatattttagccttccccagacag
+gtgacacagtcatctattgccgatttgtcgcgcgacacacaggccggagaagccacggtt
+attcgcttttgtcgcaccctgggctataaaggttttcaggattttaaaatggacctggcc
+attgaacttgccactaccgagtctgatgacagtagtcctctactggatgccgaagttagc
+gaatccgacgatgcccacgccattggtttaaaattgcagaacaccattagtaatgtatta
+tctgaaacgctaaatctgcttgatatgcaacaggttctcggtgtcgtggacgccctacgt
+cactgtcactcagtttatatctttggtgtgggctcatcggggatcacggcgctggatatg
+aaacacaagctaatgcgtattggtttacggggcgatgcggtaagcaataaccattttatg
+tacatgcaggctacgctattaaaagcaggcgatgtcgcgatgggtgtcagtcactcgggc
+acatcgccagaaacagtgcattcactccgattggcccgacaggctggcgccaccacagtc
+gccattacccataatctgggttctccattatgtgaagaggccgatttttgcctgatcaat
+ggtaatcggcaaggaatgttgcagggtgactcgatcggtacgaaagccgcgcagcttttc
+gtctttgacctgctctatacccttcttgtacagtcctcgccggaacaggcccgagaaagc
+aaattacggacaatgaatgccctggacatgacaaaataaATGAAGAAACTGCCCGGCTTT
+ACGCAAGATTACTTACTCAGCAAGGCGACGACCCTGCCTGATAAAACACGCCTGGAGCGT
+GCCGTTGAACCGCTATGCGCGCGCCATCCCGGAGAGTGCGGCATTCTTGCGCTGGATAAC
+AGTCTGGACGCTTTTGCCGCCCGCTACCGCCTGACCGAAATGGCGGCGCGGACGCTGGAT
+GTGCAGTATTATATTTGGGAAGACGATATGTCCGGGCGGCTGCTCTTTTCGGTTCTGCTG
+TCGGCGGCGAAGCGCGGCGTTCATGTTCGTCTGCTGCTGGATGATAACAATACGCCTGGT
+CTGGATGATACGTTGCGCTTGCTGGATAGCCATCCTAATATCGAAGTTCGTCTGTTTAAT
+CCTTTCTCTTTTCGTACGCTACGCGCGCTGGGATATTTGACGGATTTTGCGCGGCTGAAT
+CGGCGGATGCACAATAAAAGTTACACTGCCGACGGCGTAGTGACGCTGGTCGGTGGGCGC
+AACATCGGCGATGCCTATTTCGGCGCTGGCGAGGAGCCGCTATTTTCCGATCTGGACGTG
+ATGGCCATTGGCCCGGTGGTCAATGATGTCGCCAATGATTTTGAACGTTACTGGCGCTGT
+AGTTCAGTGTCGACATTGCAGCAAGTATTATCCCTTTCTGAGCAGGAACTGACGCAGCGT
+ATCGAACTTCCCGAATCCTGGTATAACGATGAGATCACCCGCCGTTATCTGCATAAGCTG
+GAAACCAGCCAGTTTATGGCGGATCTCGATCGCGGAACGTTGCCGCTGATTTGGGCAAAA
+ACACGCTTGCTTAGCGATGACCCTTCTAAAGGCGAGGGGAAGGCGCAGCGCCATTCGCTT
+CTTCCGCAGCGATTATTTGACGTGATGGGGTCGCCGACGGAGCGTATCGACATTATTTCC
+GCTTACTTTGTCCCTACGCGCGCAGGCGTGGCGCAGTTGCTTAATCTGGTCAGGAAAGGT
+GTGAAGATCGCCATCTTAACTAACTCTCTGGCGGCCAACGATGTGGCGGTCGTTCACGCA
+GGGTACGCGCGCTGGCGCAAGAAATTACTGCGCTATGGCGTGGAGCTCTACGAACTGAAA
+CCGACCCGCGAACATGAAACCGCCGTACATGATCGCGGACTCACCGGGAACTCAGGTTCC
+AGCTTACATGCTAAAACGTTCAGTATTGATGGTAGTAAGGTGTTTATCGGGTCGCTTAAT
+TTTGATCCCCGTTCAACGCTTTTAAATACCGAAATGGGCTTTGTCATTGAAAGTGAAACG
+CTGGCGACGCTTATTCATAAGCGTTTTACGCAGAGCCAACGCGATGCGGCCTGGCAACTG
+CGGCTGGATCGCTGGGGACGAATTAACTGGATCGATCGTCAGCAAGAAGAGGAAAAGGTG
+TTAAAGAAAGAACCCGCTACGCGTTTCTGGCAGCGAGTTCTGGTACGGTTGGCGGCAATT
+TTACCTGTGGAATGGTTGCTGTGAATGCCAACTCAAGAAGCAAAAGCGCACCGCGTCGGC
+GAATGGGCAAGCCTGCGTAATACGTCGCCGGAAATTGCCGAAGCCATTTTTGAAGTCGCT
+CACTATGACGAGAAACTGGCAGAAAAAATATGGGAAGAAGGTAGCGATGAGGTGCTGATC
+AAAGCCTTTGAGAAAACGGACAAAGACTCGCTCTTCTGGGGCGAACAAGTCATCGAACGT
+AAGAACGTATAAatgtatcccgttgacctgcatatgcataccgtcgccagcactcatgcc
+tacagtactctgagcgattatatcgcggaagccaaacgcaaaggcattaaactttttgcg
+attaccgatcatggtccggacatggaagatgcgccgcatcactggcattttattaacatg
+cgcatctggccgcgtctggttgacggcgtggggatactgcgtggcattgaggcgaatatc
+aagaatattaacggtgaaattgattgttccggaaagatgttcgactcgctggatctgatt
+atcgcaggctttcatgagcccgtttttgcgccgcatgataaagaaaccaatactcaggcg
+atgatcgcgaccatcgccagcggcaaggtgcatataattagtcaccccggaaatccaaag
+tatccagtggaggttaaagccatcgcgcaggcggcggcgaaacaccatgtagcgctggaa
+atcaacaactcttcttttctgcattcgcgtaaaggaagcgaagataattgccgcgcggtc
+gctgccgccgtacgcgatgcgggaggctgggtagcgttaggctctgattcccatacggcc
+tttacgcttggcgatttcaccgaatgccggaaaattctggatgcggtgaattttccggaa
+gatcgaatcctgaacgtctctccgcagcgcttactggcctttctcgaatcacgcggtatg
+gcgcctgtaccggaatttgccgaactttaaatgaatgagttttcaatcctgtgccgtgtg
+ctgggatcgttgttttaccgccaaccgcaagatcctttactggttccgctgtttacgtta
+atccgtgaaggtaaactggcggcaaactggccgctggagcaggatgacatgctggcgcgt
+ttacagaaaagctgcgatatcacgcagatttccactgattacaatgcgttatttgttggg
+gaagagtgcgcggtagcgccataccgcagtgcgtgggtcgaaggcgcggaagagtctgag
+gtgcgcgcttttttaacgtcgcgagggatgccgctggccgatacgcctgccgatcacatt
+ggcactttattgctcgcggcctcctggctggaagatcagtctgccgaagatgaaagtgaa
+gcgctggaaaccttatttgccgattatctgcttccctggtgcaataccttcctcggtaaa
+gttgaagcccatgccgttacgccattctggcgcactctggcgccgctaacgcgtgatgcg
+ataggggccatgtgggatgaacttcaggaagaagatgaagaataaatgatgcgcgccatg
+aacatacttctttctattgctatcactacgggcatcctttctggaatatggggatgggtg
+gccgtctccctggggttactaagctgggccggttttttaggctgtacggcttatttcgcc
+tgtccgcagggcggctttaagggattgttgatttccgcctgtacgctgttaagcggtatg
+gtgtgggcgctggtcattattcacggtagcgcgttggcgccgcatctggaaattgtcagt
+tacgtgttgacggggatcgtggcattcctgatgtgtatccaggcaaagcagctattgctt
+tcttttgttccgggaacatttatcggcgcctgcgcgacatttgcagggcagggtgactgg
+cggttggtattaccgtcgctggcgctggggctaatctttggctatgccatgaaaaatagt
+gggctatggctggcatcacgccgcgagcaacattcagcgaatacggcggtcacaaaataa
+ATGAAAAAAAACCTGCTGGGATTCACCCTCGCATCCTTGTTATTCACGACCGGTTCCGCC
+GTGGCGGCGGAGTATAAAATTGATAAAGAAGGCCAACATGCGTTCGTCAATTTCCGCATC
+CAGCATCTGGGCTACAGCTGGCTATACGGCACCTTTAAAGATTTCGACGGCACGTTCACT
+TTTGACGAAAAAAATCCGTCAGCAGACAAAGTGAATGTGACCATTAACACCAATAGCGTC
+GACACTAACCATGCCGAACGTGACAAACACCTGCGTAGCGCGGAGTTTCTTAATGTTGCG
+AAATTCCCGCAGGCAACCTTCACCTCTACCAGCGTGAAAAAAGAGGGCGATGAACTGGAT
+ATTACCGGCAATCTGACGCTCAATGGCGTGACTAAACCGGTGACGCTGGAAGCGAAGCTG
+ATGGGCCAGGGCGACGATCCGTGGGGCGGTAAGCGCGCGGGCTTTGAGGCCGAAGGAAAA
+ATTAAGCTGAAAGATTTCAATATAACTACCGATCTCGGCCCAGCCTCACAAGAGGTGGAG
+CTTATCATCTCAGTAGAAGGCGTTCAGCAGAAGTAAATGTTACTGATGATGGCGCTGATC
+GTGCGTATTATCTGGCGGCTTTATTCTCCGCCGCCCGTTGCGTTGACCAGCTATTCCCGT
+TTAACGCGCATTGGCGCCGCCGCGGGTCATATCCTTCTGTATCTCCTGCTCTTTGCGATA
+ATCATTAGCGGCTACCTGATTTCCACCGCCGACGGTAAACCGATTAGCGTCTTTGGCTGG
+TTTGAGATTCCGGCCACGCTTACGGACGCGGGCGCGCAGGCTGACATCGCCGGAACACTG
+CATCTGTGGTTTGCCTGGTCGCTGGTCATTATCTCGCTCTCGCATGGGGTTATGGCGCTA
+AAACACCATTTCATCGATAAAGACGACACACTGAAACGTATGACAGGAATGTCGTCATCT
+GACTATGGAGCTCAAAAATGAATGGTTAAGTTATCAATGACGCTGCGCCTGACAATTTCT
+TTTATCGCCATACTTATCCTCGCCTGTACCGGCATTAGCTGGACGCTCTATAACGCGCTG
+AGCAAAGAATTAACGTATCGGGATGATATGACGCTAATAAATCGGGCGGCGCAAATGCAG
+CAACTGTTACTGGATGGCGCCAGGCCGGAAAATCTGCCGCTCTATTTCAATCGGATGGTG
+GATACGAAGCAGGATATCTTATTGATCCACTCAGCAACAGGCCATAATGTTGCGATTAAT
+CATAGCGGCATCCCCGACCAACGCTTTAACGAGATTCCGCTGGCTAAAAACATCACCCGC
+GAAACCTTATTTCGCCAGGCGGTACAAGGCACGGAGCTGACCGCGGTACGAGTAAACGCC
+AGAAGCGGCGATAACCCGCTGACCCTTACTATTGCCAGGCTGGCGACGGAAAGGCGGCAA
+ATGCTGGCGCAATATCGCCGCAACAGTTTGCTGATTAGCCTTATCGCGATCCTCGTCTGT
+TCGGCGCTCAGTCCATTAGTCATCAGAAACGGGCTGCGGGCCATTACGTCGCTCAGCCGA
+CTCACCGCGGCGACAGATAGCGGCACACTTCGCCAGCCGCTGGCGGAACAGGCGTTACCC
+GTCGAGCTCAGGCCGCTTGGGCAAGCGCTAAATACCATGCGCCAGAAGCTTTCCGACGAT
+TTTGAACGCCTGAACCAATTTGCCGACGATCTGGCGCATGAGCTGCGCACGCCGGTTAAT
+ATTTTACTGGGGAAGAATCAGGTTATGCTGAGTCAGGAACGCAGCGCCGAAGAGTATCAA
+CAAGCCCTTGTCGATAATATTGAAGAGCTGGAGGGACTGTCGCGACTGACAGAAAATATT
+CTCTTTCTGGCACGCGCGGAGCACCAGAATATAGCGGTAAAAAAACAGCCTGTTTCGCTC
+AATGCGCTGGTCGAAAATATGCTGGATTATCTTAGCCCCCTTGCCGAAGAGAAGCACATC
+TGTTTTATAAATCAATGTCAGGGAACGGTATGGGCTGACGAAATATTATTACAAAGAGTG
+CTCTCAAACCTGCTGACGAATGCCATCCGTTATTCTGATGAAAACGCCGTGATACGTATT
+GAAAGCGCTTATGATGATAACGTTGCAGAAATTCGGGTCGCTAATCCGGGCAGCCCCACC
+GCCGATGCGGATAAGCTTTTCCGGCGTTTTTGGCGAGGAGATAATGCCCGCTACACTGCC
+GGTTTCGGCCTGGGGTTATCGTTAGTTAACGCGATTGCCCTATTGCACGGTGGCTCGGCA
+TCTTACCGCTATGCCGATGAACATAATATCTTTTCGGTTCGTCTGCCTGATAGCGGTGAT
+AGCTAAgtgatatgtctcaaagtccagggcggcattggtgaaatttttacggtgacgcag
+caggcggataaattctttccggctacgcagttccactggagctggacggaaagcacagta
+cctgtattgatgattggttttctgtttgccaatattcagcaatttactgccagtcaggat
+gtggtccaacgctatatcgtgactgactccatagaggaaacgaagaaaacattacttaca
+aatgccaaactggttgctgtgatccctgttttcttttttgctatcggctcggcattattt
+gtctactatcagcaacatccacaattattaccggcgggattcaacactggcggcattttg
+cccttattcgtggtcaccgaaatgccagtcggcattgcagggttgataatctccgctatt
+ttcgctgccgcgcagtccagcatctccagcagcttaaacagcatttccagttgttttaat
+tccgatatctatcagcgtttgagtcataaaaaaggaacgccagaaaaccgtatgaaaata
+gctaagttagttattctggtcgcgggcctgataagtagcgcggcctcggtatggctggtc
+atggccgatgaatcagaaatctgggatgcatttaatagtctgataggtctgatgggaggg
+ccaatgaccggtctgttcatgctgggcattttctttaaacgagcaaatgccgggagtgcg
+gttttaggaattattatcagcgtcattaccgtgctgggcacacgctatgccactgacctt
+aacttcttcttttatggggtcattggctcgctaagcgtggtgatcagcggcgttattttc
+gccccgttatttgccccggcaccgccattgacgctggatgaaaaacctgaaccaaaggtg
+acattatgaATGAAAATCAACAGATATCTTCTGGGTATGGTTTCGTTTATAGCATTTTCA
+TCATATCTACAAGCGGCAACCCTTGATTATCGGCATGAATATGCTGATAGAACCAGAATT
+AATAAAGACCGTATTGCTATAATTGAAAAGCTTCCTAACGGCATTGGTTTTTATGTCGAT
+GCCAGCGTTAAATCGGGAGGAGTAGATGGTGAGCAGGATAAGCATTTAAGCGATCTCGTC
+GCAAACGCTATAGAACTGGGCGTAAGTTATAATTATAAAGTTACGGACCATTTTGTTTTG
+CAGCCTGGATTTATATTTGAAAGCGGTCCAGACACTTCAATTTATAAGCCTTATTTAAGG
+GCGCAATATAATTTTGATTCTGGTGTTTATATGGCTGGTCGTTACCGTTATGACTATGCA
+AGGAAGACAGCTAACTATAATGATGATGAGAAAACGAATAGATTTGATACTTATATAGGT
+TATGTTTTTGATGAGTTGAAATTGGAATATAAATTTACCTGGATGGATAGCGATCAAATT
+AAATTTGATAACAAAAAAACAAACTATGAACATAATGTGGCTTTAGCCTGGAAACTGAAT
+AAGTCATTTACACCATACGTTGAGGTCGGAAATGTAGCGGTGAGAAATAATACCGATGAG
+AGACAGACCCGTTATCGCGTTGGATTACAATACCACTTTTGAATGACGAAATACGGTGTT
+ATAGGTACAGGTTATTTTGGCGCTGAACTGGCGCGATTTATGTCTAAGGTTGAAGGGGCG
+AAAATCACTGCGATTTACGATCCGGTAAATGCGGCTCCGATAGCGAAAGAGCTGAACTGT
+GTCGCCACTTCAACGATGGAGGCGCTTTGTACCCATCCTGATGTGGATTGCGTAATTATT
+GCTTCACCAAATTACTTACATAAAGCGCCGGTCATTGCGGCGGCTAAAGCGGGTAAACAC
+GTGTTTTGTGAAAAACCTATCGCCTTAAATTACCAGGATTGTAAGGATATGGTTGATGCC
+TGCAAAGAAGCTGGTGTTACCTTTATGGCGGGTCACGTTATGAACTTTTTTCACGGGGTT
+CGCCACGCTAAAGCGCTCATCAAAGCCGGTGAAATCGGTGAAGTTACACAAGTTCACACT
+AAACGTAATGGTTTTGAAGACGTGCAGGATGAGATCTCATGGAAGAAGATTCGCGCAAAG
+TCAGGTGGGCATCTGTACCATCACATTCACGAGCTAGATTGTACACTGTTCATCATGGAT
+GAAACCCCATCCCTGGTTTCAATGGCGGCGGGGAATGTTGCGCACAAAGGTGAAAAATTT
+GGTGATGAAGATGATGTTGTCCTAATCACCCTTGAGTTTGAAAGCGGTCGTTTCGCGACA
+CTTCAGTGGGGATCATCGTTCCACTACCCTGAGCACTATGTATTAATTGAGGGCACGACA
+GGTGCAATTCTCATTGATATGCAAAACACGGCTGGTTATCTAATAAAAGCGGGCAAAAAA
+ACACACTTTCTTGTGCATGAAAGCCAGGCGGAGGATGATGATCGTCGCAACGGTAACATA
+TCCAGCGAGATGGATGGCGCAATCGCTTATGGTAAACCCGGTAAACGTACGCCGATGTGG
+CTCTCATCAATTATGAAACTGGAGATGCAGTACTTGCATGATGTGATAAACGGTCTGGAG
+CCAGGCGAGGAGTTTGCTAAATTGCTAACGGGAGAAGCGGCGACAAATGCCATTGCTACC
+GCTGATGCTGCGACGCTTTCTTCAAACGAGGGGCGCAAAGTTAAACTCACTGAAATTCTT
+GGCTAAATGACATCACGTCTTCAGGTCATACAGGGTGATATCACTCAACTTAGCGTCGAT
+GCGATTGTGAATGCCGCTAACGCATCATTAATGGGCGGCGGTGGCGTAGACGGCGCAATT
+CATCGCGCGGCGGGGCCGGCATTGCTGGACGCCTGTAAACTCATCCGTCAGCAACAGGGC
+GAATGTCAGACGGGACATGCGGTTATCACGCCTGCTGGCAAGCTTTCGGCAAAGGCGGTT
+ATTCACACAGTGGGGCCCGTCTGGCGAGGCGGCGAACACCAGGAAGCTGAGCTACTCGAA
+GAGGCATACCGGAATTGTTTGCTGCTTGCCGAGGCGAATCACTTTCGTTCCATCGCTTTT
+CCGGCAATCAGTACCGGCGTTTATGGCTATCCACGCGCCCAGGCCGCTGAAGTCGCCGTC
+AGGACGGTTTCAGATTTTATTACCCGTTACGCTCTGCCTGAACAGGTATACTTTGTCTGT
+TATGATGAAGAAACTGCCCGGCTTTACGCAAGATTACTTACTCAGCAAGGCGACGACCCT
+GCCTGA
+>real_data_2
+ATGAAAAAATCATTACTCGCTGTTGCTGTGGCAGGGGCTGTTTTGTTGTCATCCGCCGTA
+CAGGCGCAGACAACGCCGGAAGGTTATCAATTACAACAGGTGCTGATGATGAGCCGCCAT
+AATCTGCGGGCGCCGCTGGCGAATAATGGCAACGTACTGGCGCAGTCGACGCCGAACGCC
+TGGCCGGCGTGGGACGTTCCCGGCGGGCAACTGACGACGAAAGGCGGCGTGCTGGAAGTC
+TATATGGGACACTACACACGTGAATGGCTGGTCGCGCAGGGGCTGATACCGTCGGGAGAA
+TGTCCGGCGCCCGACACGGTATATGCCTATGCGAATAGTTTGCAGCGCACCGTCGCCACC
+GCGCAATTTTTCATTACCAGCGCTTTCCCCGGCTGTGATATTCCTGTTCATCATCAGGAA
+AAAATGGGCACTATGGACCCTACCTTCAATCCGGTGATTACCGATGATTCCGCCGCGTTC
+CGGCAACAGGCCGTACAGGCGATGGAAAAGGCGCGTAGTCAGCTACATCTTGATGAGAGT
+TATAAACTGCTTGAGCAGATAACGCATTATCAGGACTCGCCGTCCTGCAAAGAGAAGCAT
+CAGTGTTCGCTAATCGACGCGAAAGATACCTTCAGCGCGAACTATCAGCAAGAGCCTGGC
+GTGCAGGGGCCGCTGAAAGTAGGGAACTCGCTGGTGGATGCGTTTACCCTGCAATATTAC
+GAAGGCTTTCCGATGGATCAGGTCGCTTGGGGCGGGATCCACACCGATCGGCAGTGGAAG
+GTGCTGTCAAAACTGAAAAACGGCTACCAGGACAGCCTGTTTACCTCACCCACGGTGGCG
+CGCAATGTCGCTGCGCCGCTGGTAAAATATATCGATAAGGTGCTGGTTGCCGAGCGCGTT
+AGCGCGCCGAAGGTTACCGTGCTGGTGGGGCATGATTCCAATATCGCGTCGCTGCTGACG
+GCGCTGGATTTTAAACCCTATCAGCTCCATGACCAGTATGAGAGAACGCCGATTGGTGGT
+CAGCTTGTCTTCCAACGCTGGCATGACGGTAACGCTAACCGGGATTTGATGAAAATCGAG
+TATGTCTACCAGAGCGCCCGGCAGTTACGTAATGCGGAAGCGTTAACGCTCAAATCGCCT
+GCGCAAAGGGTAACGCTGGAACTGAAAGGATGTCCGGTGGATGCGAACGGCTTCTGTCCG
+CTGGATAAGTTCGATAACGTCATGAACACTGCTGCAAAATAGATGGAAAAGAATAATGAA
+GTCATTCAGACCCATCCGCTTGTAGGATGGGACATCAGCACCGTCGATAGCTATGATGCG
+CTGATGCTGCGTTTACACTACCAGACCCCAAATCGTCCGGAACCGGAAGGGACTGAAGTT
+GGTCAAACGCTCTGGTTAACGACAGATGTAGCCAGGCAATTTATTTCAATATTAGAAGCC
+GGCATCGCCAAAATAGAATCAGGCGATTACCAGGAAAACGAGTATCGTCACCATTAGATG
+GAACTTAAGGATTATTACGCCATTATGGGCGTGAAACCGACGGACGATCTCAAGACGATT
+AAGACCGCCTATCGCCGACTGGCCCGCAAGTACCATCCAGATGTCAGCAAAGAACCCGAT
+GCCGAAGCCCGTTTCAAAGAGGTTGCTGAAGCATGGGAAGTGCTGAGTGATGAGCAACGG
+CGCGCCGAGTATGACCAGTTATGGCAACACCGTAACGATCCACAATTTAATCGCCAGTTC
+CAGCAACACGAAGGCCAGCCGTATAACGCCGAAGATTTTGATGATATTTTCTCGTCTATT
+TTTGGTCAGCACGGTCGTCATTCGCACCACCGCCACGCCGCACGCGGTCATGATATCGAA
+ATTGAAGTGGCGGTATTCCTGGAAGAAACGCTGGAAGAGCACCAGCGTACGATTAGCTAT
+TCCGTCCCCGTTTATAACGCGTTCGGCCTGGTGGAGCGGGAAATTCCCAAAACATTGAAT
+GTGAAAATCCCGGCTGGCGTCAGCAACGGGCAACGAATCAGACTGAAAGGCCAGGGCACG
+CCGGGGGAAAACGGCGGACCTAATGGCGATTTATGGCTCGTTATCCATATTGCCCCGCAT
+CCGCTCTTTGATATCGTCAATCAGGATCTGGAAGTCGTCCTTCCGCTTGCCCCATGGGAG
+GCGGCGCTCGGCGCTAAGGTGTCTGTGCCAACGCTTAAAGAGCGTATTTTGCTGACCATT
+CCCCCCGGCAGCCAGGCAGGTCAGCGGCTGCGTATCAAAGGAAAAGGATTAGCCAGTAAA
+AAGCACACTGGCGATCTCTATGCCATCATCAAAATCGTTATGCCGCCGAAACCTGACGAG
+AAAACAGCTGCCCTGTGGCAACAACTGGCGGACGCGCAGTCGTCCTTTGACCCACGCCAG
+CAATGGGGGAAAGCATAAATGGCTAACATCACTGTCACCTTTACCATCACCGAATTTTGT
+TTGCACACCGGCGTGACGGAAGAGGAGCTAAACGAAATCGTCGGACTTGGCGTAATTGAG
+CCTTACGAAGACGATAACGCCGACTGGCAATTCGACGATCGCGCAGCGAGCGTGGTACAA
+CGCGCGCTACGCTTACGCGAGGAGCTGGCGCTCGACTGGCCAGGGATCGCGGTCGCGTTA
+ACGCTGCTGGAAGAGAATTCACGGCTGCGCGAAGAAAACCGGTTACTGCTGCAACGCCTT
+TCTCGCTTTATCTCGCATCCCTAAATGTCATCTTGTTGGAGATTTACGGATTCGCTAACA
+AGCCTATGGCATACTGCGTTGATGAAGATTTTATTGATTGAAGATAACCAGAAAACCATT
+GAGTGGGTACGTCAGGGACTCACGGAGGCAGGCTATGTGGTTGATTATGCCTGTGATGGA
+CGAGACGGATTACACCTAGCCCTTCAGGAACATTATTCATTGATTATTCTTGATATTATG
+CTGCCGGGGCTTGATGGATGGCAGGTTTTACGCGCGTTGCGCACTGCATATCAGCCCCCT
+GTTATTTGCCTGACGGCGCGCGACTCGGTTGAGGATCGCGTCAAAGGTCTTGAGGCGGGC
+GCTAATGATTACCTTGTTAAGCCTTTTTCCTTCGCCGAACTGCTGGCCCGGGTGAGAGCT
+CAACTCAGACAGCATGTCCCGGTCTTTACCCGACTGACGATCAATGGTCTGGACATGGAT
+GCCACAAAGCAATCGGTGTTACGAAATGGCAAACCGATTTCCCTGACCCGCAAAGAATTC
+CTGCTCCTCTGGTTACTGGCGTCCCGGGCAGGGGAAATCGTGCCCCGAACCGCGATCGCC
+AGCGAAGTTTGGGGAATTAACTTTGATAGTGAAACCAACACCGTTGATGTCGCGATTCGT
+CGGCTGCGCGCCAAAGTAGACGATCCATTTGAAAAGAAGCTCATTATGACCGTCCAGGGG
+ATGGGTTATCGATTACAGGCGGAAACGTCGCAGAATGGTTAAatgaaaaacaaattgtta
+tttatgatgttggcaatactgggtgcgcctgggattgcaaccgcgacaaattatgatctg
+gctcgttcagaggataattttgcggtaaatgaattaagcaagtcttcatttaatcaggcg
+gccattattggtgaagtcggcacggataatagtgccagagtacgccaggaaggatcaaaa
+ctattgtccgttgtttcacaagaaggagaaaataatcgggcgaaagtcgaccaggcaggg
+aattataactttgcgtatattgagcaaacgggcaatgccaacgatgccagtatatcgcaa
+agcgcttacggtgatagtgcggctattatccagaaaggttctggaaataaggccaatatt
+acccagtacggtgcgcagaaaacagcagttgtagtgcagaaacagtcgcatatggctatt
+cgcgtcacccaaggctaaatgcatactttattgctccttgccgcactttcaaatgagatt
+acgtttaccacgactcagcaaggcgatatttacacggtgatccctcaggtcacagtaaac
+gaaccctgcgtctgtctggtgcaaattctctctgtgcgcgacggcgtcgggggagaaagc
+catacacagcaaaaacaaacgctatctttacctgctaatcaaccgattgagttggctcgt
+cttagtgtaaatatatcttcagaggactcggttaaaattattgttactgtttcggacgga
+caatcactgcatttatcacaacaatggccgccttctgcacagtagatgtttaatgaagtc
+catagtagtcatggtcacacactattgttgatcacaaagccatctctgcaagctacggca
+ttattgcaacatttaaagcaatcgctggccataaccggacaactgcataatattcaacgt
+tctctggaagatatctcagccggttgcattgttttaatgcatatgatggaagcggataag
+aagcttatccactattggcaggataatttaagccgcaaacacaataatataaaaacatta
+ttgttaaatacccctgacgattatccctaccgtgaaattcaaaactggcctcatattaac
+ggcgtgttttacgccactgaagaccaggaacacgtggtccgcggattacagggtattctg
+cggggcgaatgctatttttcacaaaaattagccagttacctgattacacactcaggaaat
+taccgctacaacagcaccgagtccgcattactcactcatcgcgaaaaagagatcctcaat
+aagttacgtattggtgcctctaataatgaaatcgccaggccgctatttatcagcgagaat
+acggttaagacacatctttataatcttttcaaaaagatacctgtcaaaaatcgcacccag
+gcagtttcatgaatgaaacgctatctgacctggattgtagcagcagagttactgttcgct
+accggaaacctccatgccaatgaagttgaagtcgaggttcccggattgttaaccgaccat
+accgtctcttccataggacatgaattctatcgtgcattcagcgacaaatgggaaagcgaa
+tacaccggcaacctgaccattaatgaaagacccagtgcgcgttggggaagctggatcacc
+ataacggtaaaccaggacgttattttccagacctttttatttccaatgaaaagagacttc
+gagaaaaccgtcgtcttcgcattagcgcaaacagaggaagcattaaatcgccgacaaata
+gatcaaacgctcttaagtacgagtgatttagcgcgtgatgaattctaaatgcgtgttaaa
+catgcagtagtgctgctcatgcttttttcgccattaacctgggctcgaaatatgacgttc
+cagttccgtaatcctaactttggtggaaaccccaataacggttcccttttattgaatagc
+gcccaggcgcaaaattcatataaagaccccgcttatgataacgatcttggtatcgagacc
+ccctcagcgttggataactttacgcaggctattcaatcgcaaattctgggcggcttgttg
+accaatattaataccggaaaaccaggacgtatggtgaccaatgatcttattatcgatatc
+gctaatcgcgacggacagctccagctcaacgtcacggacagaaaaccgggaagaacctcg
+accatcgaagtgtcaggtttacaaactcagtcaaccgatttttaaatgccgcgcttactt
+attttggttgccgttttatcgttgagcggatgcttaactgccccgccgaaacaagctgcg
+aaaccgacattaatgccccccgcacaaagttacaaagatttgacgcacttacctgctccc
+accggtaagatctttgtttcggtatataacattcaggatgaaacgggccaatttaaacct
+tacccggcaagtaacttttccacggctgtgccgcagagcgccaccgctatgttggtcacc
+gcgctgaaagattcgcgctcgtttatcccactagaacgacaaggcttacagaatcttttg
+aatgaacggaaaattattcccgcagcccaggaaaacggcaccgtggcgatgaataaccgt
+atcccgcttcagtcgttgacggcggcaaatattatggtggaaggttctattattggttat
+gaaagtaacgtcaaatccgccggggtcggcgcaagatatttcggtattggcgccgatacg
+cagtatcagctggatcagactgctgtcaacctgcgcgtggttaacgtcagtacgggcgag
+atcctttcttcggtgaacaccagtaaaacgatcctttcctatgaagtacaggcaggcgtg
+ttccgttttattgattacccgcgcttactggaaggcgaaatcggctatacctcgaacgaa
+ccggtgatgctgtgtctgacgtcagccattgaaaccggcgttatcttcctcattaatgat
+ggtatcgatcgcggactgtcggatttgcagaataaagcggacaggcaaaatgatattctg
+gtgaaataccgtgagctgtcagtaccgccagaatcctgaATGTCTATTGCCGTAAATATG
+AATGACCCGACCAACACGGGCGTCAAAACGACGACCGGCAGCGGGTCGATGACCGGAAGC
+AACGCTGCCGATCTGCAAAGCAGTTTCCTGACCTTACTGGTCGCGCAATTGAAGAACCAG
+GACCCGACTAACCCATTACAAAATAATGAGTTAACGACACAGTTGGCGCAAATCAGTACC
+GTGAGCGGCATTGAAAAACTGAATACGACGCTGGGGGCTATTTCCGGGCAAATCGATAAT
+AGTCAGTCCCTACAGGCGACCACGCTGATTGGACATGGCGTTATGGTGCCTGGCACCACA
+ATTCTGGCGGGTAAAGGCGCGGAAGAAGGGGCCGTGACGTCCACGACGCCGTTTGGCGTG
+GAATTGCAACAGCCTGCGGACAAAGTGACGGCAACCATTACCGATAAAGATGGCCGGGTG
+GTACGGACGCTGGAGATCGGTGAGTTGCGAGCCGGGGTACACACCTTTACCTGGGATGGT
+AAGCAAACGGACGGAACAACGGTACCGAATGGTTCTTACAACATTGCGATTACCGCCAGC
+AATGGCGGGACGCAACTGGTGGCGCAGCCGCTGCAATTCGCTCTGGTACAGGGCGTGACG
+AAGGGCAGTAACGGCAACCTGTTGGATCTGGGTACCTACGGCACCACCACACTCGACGAA
+GTTCGGCAAATAATCTAAATGTCTTTTTCTCAAGCGGTTAGCGGCCTGAACGCTGCGGCC
+ACCAACCTTGATGTTATCGGTAATAACATCGCCAACTCCGCCACCTATGGCTTTAAGTCC
+GGTACGGCATCATTTGCCGATATGTTCGCCGGTTCCAAAGTGGGGTTGGGCGTAAAAGTG
+GCGGGGATTACCCAGGATTTTACCGACGGTACGACAACGAACACCGGGCGCGGGCTGGAT
+GTCGCGATTAGCCAGAACGGTTTTTTCCGCCTGGTAGACAGCAACGGTTCCGTGTTCTAT
+AGCCGCAACGGCCAGTTCAAACTGGACGAGAACCGTAACCTGGTCAATATGCAGGGGATG
+CAGTTGACCGGCTATCCGGCCACCGGTACGCCGCCGACCATTCAGCAGGGGGCGAATCCT
+GCGCCGATCACCATTCCGAACACGCTGATGGCGGCGAAATCGACCACCACCGCGTCAATG
+CAGATCAACCTGAACTCAACGGACCCTGTACCGTCTAAAACGCCCTTTAGCGTGAGTGAT
+GCGGATTCGTATAACAAAAAAGGCACCGTCACCGTTTATGACAGCCAGGGTAATGCCCAT
+GACATGAACGTCTATTTTGTGAAAACCAAAGATAATGAATGGGCTGTGTACACCCATGAC
+AGCAGCGATCCTGCAGCCACTGCGCCAACAACGGCGTCCACTACGCTGAAATTCAATGAA
+AACGGGATTCTGGAGTCTGGCGGTACGGTGAACATCACCACCGGTACGATTAATGGCGCG
+ACAGCGGCCACCTTCTCCCTCAGCTTCCTTAACTCCATGCAGCAGAACACCGGGGCTAAT
+AACATCGTCGCCACCAATCAAAACGGCTATAAGCCTGGCGACCTGGTGAGCTACCAGATT
+AACAATGATGGCACCGTGGTTGGCAACTACTCCAACGAGCAGGAGCAGGTGCTGGGGCAG
+ATTGTGCTGGCTAACTTCGCCAACAACGAAGGTCTGGCATCCCAGGGCGATAACGTCTGG
+GCGGCGACGCAGGCCTCCGGGGTAGCGCTGCTGGGGACTGCCGGTTCCGGCAACTTCGGT
+AAGCTGACGAACGGCGCGCTGGAAGCCTCTAACGTGGATTTGAGTAAAGAGCTGGTGAAT
+ATGATCGTCGCGCAGCGTAACTACCAGTCGAATGCGCAGACCATCAAAACCCAGGACCAG
+ATCCTCAATACGCTGGTTAACCTGCGCTAAATGGATCACGCAATTTATACCGCCATGGGG
+GCGGCCAGCCAGACGCTTAACCAGCAGGCGGTAACGGCCAGCAACCTGGCTAATGCCTCA
+ACGCCGGGCTTTCGCGCGCAGCTTAACGCGCTACGCGCGGTGCCCGTTGATGGCCTCTCT
+TTAGCGACGCGCACGTTGGTTACGGCGTCGACGCCGGGGGCGGATATGACCCAGGGTCAG
+TTGGACTACACTTCCCGCCCGCTGGATGTTGCGTTACAGCAGGACGGCTGGCTGGTGGTG
+CAAGCGGCGGATGGCGCTGAAGGATATACCCGTAACGGGAATATCCAGGTGGGCCCGACC
+GGGCAGTTAACCATTCAGGGACATCCGGTTATCGGCGAAGGCGGCCCGATTACCGTTCCG
+GAAGGGTCGGAAATCACCATTGCGGCAGACGGCACGATCTCCGCGCTCAATCCCGGCGAC
+CCGCCAAACACGGTGGCGCCCGTTGGGCGGCTGAAGCTGGTCAAAGCGGAAGGCAATGAG
+GTGCAGCGGAGCGATGACGGTTTATTCCGCCTTACCGCCGAGGCACAGGCTGAACGCGGG
+GCGGTACTGGCCGCCGACCCGTCAATTCGCATTATGTCGGGCGTGCTGGAGGGCAGTAAC
+GTCAAGCCGGTTGAAGCCATGACCGACATGATCGCCAACGCACGTCGTTTTGAAATGCAG
+ATGAAGGTTATCACCAGCGTAGATGAGAACGAAGGGCGAGCTAACCAACTGCTGTCGATG
+AGTTAAATGATCAGTTCATTATGGATCGCCAAAACCGGTCTGGACGCGCAGCAAACCAAT
+ATGGATGTGATTGCCAATAACCTGGCAAACGTCAGCACCAATGGTTTTAAGCGTCAGCGC
+GCGGTATTTGAAGATCTGTTGTATCAGACCATCCGCCAGCCGGGCGCGCAGTCGTCCGAG
+CAGACGACGCTGCCTTCCGGGCTGCAAATCGGTACCGGCGTGCGTCCGGTCGCCACGGAG
+CGCCTGCACAGTCAGGGGAACCTGTCGCAGACCAACAACAGTAAAGATGTGGCGATTAAA
+GGGCAGGGCTTTTTCCAGGTCATGCTGCCGGACGGTACGTCTGCCTATACCCGCGACGGC
+TCTTTCCAGGTGGATCAGAATGGTCAACTGGTGACGGCGGGCGGTTTTCAGGTGCAGCCG
+GCAATCACCATTCCGGCCAACGCGTTAAGCATCACGATTGGCCGCGACGGCGTGGTCAGC
+GTTACCCAGCAAGGGCAGGCCGCGCCGGTTCAGGTCGGGCAGCTTAACCTGACCACCTTT
+ATGAACGACACCGGTCTGGAAAGCATCGGCGAGAACCTCTATATCGAAACGCAATCGTCC
+GGCGCGCCGAACGAAAGCACGCCGGGGCTCAACGGCGCGGGGTTGTTGTATCAAGGGTAT
+GTCGAAACGTCGAACGTTAACGTGGCGGAAGAGCTGGTGAACATGATTCAGGTTCAACGC
+GCCTATGAAATTAACAGTAAAGCAGTATCGACGACCGATCAGATGCTGCAGAAACTGACG
+CAACTCTAAATGGCCCTGATGGTCGCGACGCTGACAGGATGCGCCTGGATACCCGCTAAA
+CCGCTCGTGCAGGGGGCGACCACGGCGCAGCCGATACCTGGCCCGGTACCGGTGGCGAAT
+GGCTCCATATTTCAGTCTGCGCAGCCGATTAATTATGGCTATCAGCCGCTTTTTGAAGAT
+CGTCGACCGCGTAATATCGGCGATACGCTCACGATTGTGTTACAGGAAAACGTCAGCGCC
+AGTAAAAGCTCGTCGGCAAATGCCAGCCGCGACGGCAAAACCAGCTTTGGTTTTGATACG
+GTACCGCGTTATCTGCAGGGATTATTCGGTAATTCCCGCGCGGATATGGAGGCCTCCGGC
+GGCAACTCTTTTAATGGTAAAGGCGGCGCGAATGCCAGCAATACCTTTAGCGGCACGCTG
+ACCGTGACCGTCGATCAGGTTCTGGCCAATGGCAATTTACACGTCGTGGGGGAAAAACAG
+ATCGCGATTAATCAGGGAACGGAATTCATCCGCTTCTCCGGCGTGGTAAATCCACGCACC
+ATCAGCGGTAGCAACTCTGTTCCCTCGACACAGGTGGCGGATGCGCGGATTGAATATGTC
+GGGAACGGCTATATTAACGAAGCGCAAAATATGGGCTGGCTGCAACGTTTCTTCCTTAAT
+TTGTCGCCGATGTAAGTGTTTAAAGCTCTTGCAGGAATCGTTCTGGCACTGGTTGCCACT
+CTGGCGCACGCCGAGCGTATCCGGGATCTGACCAGTGTCCAGGGAGTACGGGAAAACTCG
+CTGATCGGCTACGGGCTGGTGGTCGGGCTGGACGGTACGGGCGACCAGACGACCCAGACG
+CCATTTACCACCCAGACGCTGAATAACATGCTGTCACAACTGGGGATTACGGTCCCCACC
+GGCACCAATATGCAGTTGAAAAACGTGGCGGCGGTGATGGTGACGGCGTCGTATCCGCCT
+TTTGCGCGACAGGGACAAACGATCGATGTCGTCGTTTCCTCAATGGGGAACGCTAAAAGT
+CTGCGTGGCGGGACGTTATTAATGACGCCGTTAAAAGGGGTGGACAGCCAGGTGTATGCT
+CTGGCGCAGGGCAATATTCTGGTCGGCGGCGCGGGCGCTTCCGCAGGCGGCAGTAGCGTG
+CAGGTTAACCAGCTTAATGGCGGGCGCATCACTAATGGCGCGATTATCGAACGCGAGTTG
+CCGACTCAGTTCGGCGCTGGCAACACCATTAATCTGCAATTGAACGACGAAGATTTTACG
+ATGGCGCAGCAAATTACCGACGCCATCAACCGCGCCCGCGGTTACGGCAGCGCCACTGCG
+CTTGATGCGCGAACGGTACAGGTACGCGTGCCCAGCGGCAACAGCTCGCAGGTGCGTTTT
+CTGGCGGACATTCAAAATATGGAAGTCAACGTGACGCCGCAGGATGCAAAAGTCGTGATC
+AACTCGCGTACCGGTTCGGTGGTCATGAATCGGGAAGTCACGCTGGATAGCTGCGCTGTG
+GCGCAGGGCAATTTGTCAGTGACAGTCAATCGCCAACTCAACGTCAACCAGCCGAATACG
+CCATTTGGCGGCGGGCAGACCGTGGTGACGCCACAGACTCAGATAGATTTGCGTCAGAGC
+GGCGGATCGCTACAGAGCGTGCGTTCCAGCGCCAATCTGAACAGCGTAGTGCGCGCGCTG
+AATGCGCTTGGCGCGACGCCGATGGATCTGATGTCGATTTTGCAGTCCATGCAGAGCGCG
+GGCTGTCTACGCGCCAAACTGGAAATCATCTGAATGATCGGAGACGGTAAATTGCTGGCC
+AGCGCGGCCTGGGATGCGCAATCTCTGAACGAACTGAAAGCGAAAGCGGGCCAGGACCCG
+GCGGCGAATATCCGTCCTGTGGCCCGTCAGGTGGAAGGGATGTTTGTGCAGATGATGCTG
+AAAAGTATGCGCGAGGCTTTACCCAAAGATGGTTTATTCAGCAGCGATCAGACGCGTCTG
+TATACCAGCATGTATGACCAGCAGATCGCCCAGCAGATGACCGCCGGTAAGGGATTGGGG
+CTGGCGGATATGATGGTTAAACAGATGACGGGCGGGCAGACGATGCCTGCAGATGATGCG
+CCGCAAGTACCGCTTAAATTCTCCCTGGAGACGGTAAACAGCTATCAAAATCAGGCGCTG
+ACCCAACTGGTGCGCAAAGCCATACCGAAAACGCCGGACAGCAGCGATGCGCCGCTCTCC
+GGCGACAGTAAAGACTTTCTGGCCCGGCTTTCGCTCCCGGCGAGGCTGGCCAGCGAACAA
+AGCGGGGTGCCGCATCATCTGATTCTGGCGCAGGCGGCGCTGGAGTCCGGCTGGGGGCAG
+CGGCAAATCCTGCGGGAGAATGGCGAACCCAGCTATAACGTATTTGGCGTGAAAGCGACC
+GCCAGTTGGAAAGGGCCGGTGACGGAAATCACCACCACTGAATACGAAAATGGCGAAGCG
+AAAAAAGTGAAAGCGAAATTCCGCGTCTATAGCTCGTATCTGGAGGCGTTATCGGATTAT
+GTCGCGCTGTTAACGCGTAACCCACGCTACGCTGCCGTGACCACTGCCGCCACGGCAGAG
+CAGGGCGCAGTGGCTCTGCAAAACGCCGGATACGCCACTGACCCGAATTACGCGCGTAAA
+TTGGCCAGCATGATTCAGCAGTTGAAAGCGATGAGTGAAAAGGTCAGCAAAACCTACAGC
+GCGAATCTCGACAATCTCTTTTAAATGTCCAGCTTGATTAATCACGCCATGAGCGGACTT
+AACGCCGCGCAGGCCGCGTTAAATACGGTCAGTAATAACATCAACAATTATAACGTTGCG
+GGTTATACCCGGCAGACAACTATTCTGGCGCAGGCAAACAGTACGTTAGGGGCTGGCGGC
+TGGATAGGTAATGGCGTTTACGTTTCAGGCGTACAGCGCGAATATGATGCGTTTATCACT
+AATCAGCTACGCGGCGCGCAAAACCAGAGCAGCGGCTTAACCACGCGCTATGAACAAATG
+TCGAAAATCGACAACCTGCTGGCCGATAAATCCAGCTCACTGTCTGGCTCGCTGCAGAGT
+TTTTTTACCAGCCTGCAAACGTTAGTCAGTAATGCGGAAGATCCTGCGGCGCGTCAGGCG
+CTGATTGGTAAAGCGGAAGGGCTGGTAAACCAGTTCAAAACCACCGATCAGTATCTGCGC
+GATCAGGATAAACAGGTCAATATCGCGATTGGCTCCAGCGTGGCGCAAATCAACAATTAC
+GCGAAGCAGATAGCTAACCTGAACGATCAAATCTCCCGTATGACGGGCGTAGGCGCGGGC
+GCATCGCCGAACGACCTGCTCGATCAACGTGATCAGTTGGTTAGCGAGCTTAACAAGATC
+GTTGGCGTCGAGGTGAGTGTACAGGACGGCGGCACCTATAACCTGACGATGGCCAATGGC
+TATACGCTGGTGCAGGGGTCGACGGCGCGTCAGTTGGCGGCGGTTCCCTCCAGCGCCGAC
+CCGACGCGAACGACTGTCGCTTATGTCGATGAGGCCGCCGGTAACATCGAAATTCCGGAA
+AAGTTGCTGAACACCGGTTCGCTCGGCGGGCTACTGACGTTCCGTTCTCAGGATCTGGAT
+CAGACTCGTAATACGCTGGGCCAGTTGGCGTTGGCGTTTGCCGATGCGTTTAACGCGCAG
+CATACCAAAGGTTATGACGCCGACGGCAATAAAGGGAAAGACTTCTTTAGCATTGGCTCG
+CCGGTGGTATATAGCAACAGTAATAATGCCGATAAAACGGTATCGCTAACCGCTAAGGTG
+GTCGACAGCACGAAGGTTCAGGCGACGGATTATAAGATTGTTTTTGACGGTACAGACTGG
+CAGGTTACTCGCACTGCGGATAACACCACCTTCACGGCAACAAAAGATGCTGACGGAAAA
+CTGGAGATTGACGGTCTGAAAGTGACGGTAGGGACTGGCGCACAGAAAAACGACAGTTTT
+CTTCTCAAGCCGGTCAGCAATGCTATCGTCGACATGAACGTTAAAGTGACAAATGAAGCC
+GAGATTGCGATGGCGTCTGAGTCAAAACTCGATCCTGATGTGGATACCGGCGACAGCGAT
+AACCGCAATGGTCAGGCATTGCTGGACTTACAAAACAGCAATGTAGTGGGCGGCAACAAA
+ACCTTTAACGATGCTTACGCCACGTTGGTCAGCGATGTGGGTAACAAAACGTCAACGCTG
+AAAACCAGCAGCACCACGCAGGCGAATGTGGTTAAACAGCTTTATAAACAGCAACAGTCG
+GTTTCCGGCGTTAACCTCGACGAAGAGTACGGCAATTTGCAGCGTTATCAGCAGTATTAT
+CTGGCGAATGCGCAAGTATTGCAGACCGCGAATGCGCTGTTTGATGCGTTATTGAATATT
+CGCTAAATGCGTATCAGTACCCAGATGATGTACGAACAAAATATGAGCGGCATCACTAAT
+TCTCAGGCCGAATGGATGAAGCTGGGCGAGCAGATGTCTACCGGTAAGCGCGTTACCAAC
+CCATCTGACGATCCGATCGCCGCGTCGCAGGCGGTAGTACTCTTTCAGGCGCAGGCGCAG
+AATAGCCAGTACGCCCTGGCGCGTACGTTTGCCACCCAAAAAGTGTCGCTGGAAGAAAGC
+GTACTCAGTCAGGTGACGACGGCGATTCAAACCGCGCAGGAAAAAATCGTCTATGCCGGA
+AACGGCACGTTAAGCGACGATGACCGCGCGTCGCTGGCGACGGATTTACAGGGGATCCGC
+GATCAGCTGATGAACCTGGCAAACAGCACTGACGGCAATGGTCGCTATATCTTTGCCGGG
+TATAAAACGGAAGCGGCGCCATTCGACCAGGCGACAGGTGGTTATCATGGCGGCGAGAAA
+AGTGTTACCCAGCAGGTGGATTCCGCACGCACGATGGTAATTGGCCATACGGGAGCGCAA
+ATTTTTAATAGCATCACCAGCAATGCGGTGCCGGAACCGGATGGCTCGGACTCCGAAAAG
+AATCTGTTTGTCATGCTCGATACGGCAATTGCCGCGCTCAAGACCCCGGTGGAAGGCAAT
+GACGTGGAAAAAGAAAAAGCCGCTGCCGCCATTGATAAAACCAATCGCGGCTTAAAAAAT
+TCGCTTAATAACGTCCTGACCGTTCGTGCGGAACTGGGAACGCAACTGAGCGAACTCAGT
+ACGCTGGATTCACTGGGAAGCGACCGTGCGCTGGGACAGAAGCTACAGATGAGCAACCTG
+GTAGATGTGGACTGGAACTCGGTCATTTCCTCCTACGTCATGCAACAGGCGGCATTACAG
+GCGTCCTATAAAACGTTTACCGACATGCAGGGAATGTCGCTTTTCCAGTTGAACCGGTAA
+atggagataattttttatcacccgacatttaacgccgcctggtgggtaaatgcgctggag
+aaggctctcccacatgcgcgcgttcgtgaatggaaggtcggtgataacaaccccgcagac
+tatgcgcttgtatggcagcccccggttgaaatgctggccggaagacgcttaaaagccgtc
+tttgtgctgggcgcgggggtggatgcaattctgagtaaattaaatgcgcatccggaaatg
+ctggacgcctccattcctctattccgtctggaagataccggaatgggcctgcaaatgcag
+gagtatgccgccagccaggtattacactggttccgtcgtttcgatgattatcaggcgctg
+aaaaatcaggcgctatggaaaccgttgccggaatatacccgcgaagagtttagcgtcggt
+atcataggcgcaggggtactgggcgcaaaagtggcagaaagtctacaggcgtgggggttc
+ccgttacgttgctggagtcgtagccgcaaatcctggcctggcgtggaaagttatgtaggg
+cgtgaagaactgcgcgctttcctgaaccagacgcgggtgctgattaatctgctgccgaat
+acggcccaaacggtaggaattattaatagcgaattgttggatcaattgccggatggcgct
+tacgtgctgaatctcgcgcgcggcgttcatgttcaggaggcggatctgctggctgcgctt
+gatagcggtaagctaaaaggcgcgatgttggatgtctttagccaggaaccgttaccgcag
+gaaagtccattatggcgccatccgcgagtcgccatgacgccgcacattgcggcagtcacc
+cgtccggcggaagccatcgattatattagccgcaccattacccagctggagaagggagag
+ccggtgacggggcaggtggatcgggcgagaggatattggATGTCCGTAATCAAGAAAAAT
+ATCCCTGCCATAGGCCTGTGTATCTGCGCTTTTTTTATCCATTCTGCGGTAGGGCAACAA
+ACGGTACAGGGCGGCGTTATCCATTTTCGCGGCGCGATTGTTGAGCCACTGTGCGATATT
+TCTACTCACGCCGAAAATATTGATTTAACCTGCCTACGCGAAGGTAAAAAGCAAATGCAC
+CGGATAGACCTTCGGCAGGCATCTGGATTACCGCAGGATATTCAGTCCATTGCGACGGTA
+CGGCTGCATTATCTCGATGCGCAAAAAAGCCTGGCGGTGATGAATATTGAGTACCGTTAA
+ATGGCAAACCATCGTGGCGGTTCCGGTAATTTTGCGGAAGACCGCGAAAGAGCATCAGAA
+GCAGGTCGTAAAAGTGGTCAGCACAGCGGGGGCAATTTTAAGAATGACCCGCAGCGTGCA
+TCCGAAGCAGGCAAAAAAGGGGGCAAAAGCAGTAACCGTAATCGCTAGATGGTAATGTCC
+GCACCAGGACACATTGTTTACAGTAGTTACAACACCCTGTACGGACATTCTCTCTCCGGT
+GGTGGTCTTGTCATCTTAAAAGCTCTCATCATTTCCCTTACTGTCCATACCCATGACGCC
+ATATGTGGTGCGCGTAGCCGTGTGTGGCGTCGTTTCAAAAAGCAAGCTAAGGCTTACAAG
+GAAGCCAACCCTCAGATGTGTGTGCGCATAATCGCGTTCAAGAGAACGCGGGTGATGTAT
+ACCTACAACTCAAGGTGCTATCCATGGGAAGACAAAAAGCAGTGAATGAAACGAATTTTC
+CTTACCTGCGCGGCGTTGTTGTTCAGCAGTCAGGCGTTGGCCGATGAGTGTGCCAGCGCC
+AGTACGCAGCTGGAAATGAATCGCTGCGCCGCCGCGCAATACCAGGCGGCAGATAAAAAG
+CTGAACGAAACCTATCAAAGCGCGATTAAGCGTGCGCAACCGCCGCAGCGTGAGCTATTG
+CAAAAAGCGCAGGTGGCATGGATTGCCCTGCGCGACGCCGATTGCGCGCTGATTCGCTCA
+GGTACGGAGGGCGGCAGCGTTCAACCCATGATCGCCAGCCAGTGCCTGACCGATAAAACG
+AACGAACGCGAAGCGTTTTTAGCCTCGCTGCTGCAATGTGAAGAGGGTGATTTGAGCTGC
+CCACTGCCGCCAGCCGGTTAAgtgcgtatattcgcggtgagcataatggtgattaccctg
+agcggctgcggcagtattatcagcagaacgatccccggacaaggacacggcaaccagtat
+taccctggcgtgcagttggatatgcgtgattccgcatggcgctatatcactatcctcgat
+ctgcccttctcactgatcttcgatacactgctactgccgctcgatattcaccacgggcct
+tatgagtaaATGTGCCAACGTGCGATCGCCAATATTGATATCAGCAAAGAGTATGACGAA
+AGCATGGGCAGTAACGATGTGCATTATCAGTCGTTTGCTCGTATGGCGGATTTCTTTGGT
+CGTGATATGCAGGCGCATCGCCACGACCAGTTTTTTCAAATGCACTTTCTTGATACCGGG
+CAGATTGAGCTACAGCTCGACGATCATCGCTATTCGGTGCAGGCGCCGCTATTTGTGCTA
+ACGCCGCCCTCGGTGCCGCATGCTTTTATTACCGAATCGGATAGCGATGGTCATGTTCTG
+ACGGTACGCGAAGAGCTGGTTTGGCCGCTGCTGGAAGTGCTTTATCCCGGCACCAGAGAG
+GCCTTCGGCCTGCCGGGAATCTGCCTGTCGCTGGCGGATAAACTCAACGAGCTGGCGGCG
+CTCAAACATTACTGGCAGCTAATTGAGCGGGAGTCCACGGAACAACTGGCTGGCTGCGAA
+CATACCTTGGTACTACTGGCGCAGGCGGTATTTACCTTGCTGTTGCGTAATGCGAAGCTG
+GACGATCATGCCGCAACCGGGATGCGCGGTGAACTGAAACTTTTTCAGCGCTTTACCCTG
+TTAATTGACAACCACTTCCATCAGCACTGGACGGTGCCCGATTATGCCTGTGAGTTGCAT
+ATTACCGAATCTCGTTTGACCGATATTTGCCGACGTTTTGCTAATCGCCCGCCTAAACGC
+CTGATTTTTGATCGGCAATTACGCGAGGCGAAACGACTGCTGCTTTTTTCCGACAATGCT
+GTCAACGAGATCGCCTGGCAATTAGGTTTTAAAGATCCGGCTTATTTCGCCCGTTTCTTT
+AATCGCCTTGCTGGCTGTTCTCCTTCGCAGTTTCGCCAACGTGAAGTTCCTTCTTTTCTC
+AACTAAATGGGACGCACACCGGATTACAAAGCCGCCTTTGGCTGCGCTCTGGGCGCTAAC
+CCAGCCTTCTACGGCCAGTTTGAGCAGAACGCCCGTAACTGGTACACCCGTATTCAGGAG
+ACCGGCCTGTACTTTAACCATGCAATCGTCAACCCGCCCATTGACCGCCACAAACCTGCC
+GACGAAGTGAAAGACGTCTATATCAAGCTGGAGAAAGAGACGGACGCCGGGATTATTGTC
+AGCGGGGCGAAAGTTGTCGCCACTAACTCCGCCCTGACTCACTACAACATGATTGGTTTC
+GGCTCAGCCCAGGTGATGGGCGAAAACCCGGATTTTGCTCTGATGTTTGTCGCGCCAATG
+GATGCCGAAGGCGTAAAACTTATTTCGCGCGCCTCGTATGAAATGGTCGCGGGCGCGACG
+GGCTCGCCGTTTGATTATCCCCTCTCCAGCCGTTTTGATGAAAACGATGCCATTCTGGTG
+ATGGACAAGGTGCTGATCCCGTGGGAAAACGTATTAATTTACCGTGATTTCGATCGTTGT
+CGTCGCTGGACGATGGAAGGCGGCTTTGCCCGTATGTATCCACTGCAAGCCTGTGTTCGT
+CTGGCGGTAAAACTTGATTTCATTACCGCGCTGCTGAAAAAATCGCTCGAATGTACGGGT
+ACCGTAGAGTTCCGGGGCGTGCAGGCCGATCTCGGCGAAGTCGTGGCCTGGCGCAATATG
+TTCTGGGCATTGAGCGATTCTATGTGTTCTGAAGCAACCCCGTGGGTAAACGGCGCCTGG
+CTACCGGACCACGCCGCGCTGCAAACCTATCGTGTGATGGCCCCAATGGCCTACGCGAAA
+ATTAAAAATATTATTGAACGTAACGTTACCAGCGGCCTGATTTACCTGCCTTCCAGCGCC
+CGCGATCTGAATAATCCGCAAATCGACCAGTACCTGGCGAAATACGTACGCGGCTCTAAC
+GGAATGGACCATGTTGAACGTATCAAAATTCTTAAATTGATGTGGGATGCCATCGGCAGC
+GAGTTTGGCGGTCGCCATGAGCTGTACGAGATTAACTACTCGGGCAGCCAGGATGAAATT
+CGTCTGCAGTGTCTGCGTCAGGCCCAGAGCTCCGGCAATATGGATAAGATGATGGCAATG
+GTCGATCGCTGCCTCTCCGAATACGATCAGAATGGCTGGACGGTTTCGCATTTGCACAAT
+AACGACGACATCAATCAACTGGATAAGCTGCTGAAATAAATGCAAGTAGATGAACAACGT
+CTGCGTTTTCGCGATGCGATGGCAAGTCTGGCGGCAGCGGTCAACATCGTAACCACGGCG
+GGTCACGCCGGACGCTGCGGTATCACCGCAACAGCGGTTTGCTCAGTCACTGATACGCCG
+CCCTCCGTGATGGTATGTATTAATGCCAATAGCGCCATGAACCCCGTTTTTCAGGGCAAC
+GGCAGGCTGTGCATTAATGTACTTAACCATGAGCAGGAGCTGATGGCGCGCCACTTTGCC
+GGTATGACGGGGATGGCGATGGAGGAGCGTTTTCACCAGCCATGTTGGCAAAACGGGCCG
+CTGGGCCAGCCGGTACTTAACGGCGCGCTGGCCAGTCTTGAAGGCGAGATCAGCGAGGTA
+CAAACCATTGGCACGCATCTGGTGTATCTGGTGGCGATCAAAAATATTATTCTTAGCCAG
+GAGGGGCATGGCCTGATTTATTTCAAACGCCGTTTTCATCCGGTCAGACTTGAGATGGAA
+GCGCCTGTTTAAATGAAGGGTACTGTTTTCGCCGTTGCGTTAAACCATCGCAGCCAGCTT
+GATGCCTGGCAAGAGGCTTTCTCTCAGCCTCCCTATAATGCGCCGCCTAAAACCGCAGTG
+TGGTTCATCAAGCCGCGTAATACGGTGATTCGTCACGGCGAACCCATTCCTTATCCGCAG
+GGAGAAAAGGTACTGAGCGGCGCGACAGTGGCGCTCATTGTGGGGAAAACCGCCAGCCGG
+ATACGCCCTGAAGCGGCGGCGGACTATATCGCCGGGTATGCGCTGGCTAACGAGGTCAGC
+CTGCCGGAAGAGAGCTTTTATCGCCCGGCGATTAAAGCGAAATGTCGCGATGGCTTTTGC
+CCGCTGGGTGAAATGGCGCCGCTGAGTGATGTGGATAATCTCACCATTATCACTGAAATC
+AACGGACGAGAAGCGGACCACTGGAATACTGCCGATTTACAGCGTAGCGCCGCACAACTG
+CTTAGCGCGTTAAGTGAGTTCGCTACACTTAACCCTGGCGATGCGATCTTACTTGGTACG
+CCGCAGAATCGCGTTGCGCTGCGTCCCGGCGATCGGGTGCGTATTCTGGCGAAAGGTTTA
+CCCGCGCTGGAAAATCCGGTTGTCGCAGAAGATGAATTCGCCCGCCACCAGACGTTTACG
+TGGCCGCTGTCAGCGACGGGAACGTTATTTGCGCTGGGGTTGAACTACGCCGATCACGCC
+AGCGAGCTGGCATTTACGCCGCCGAAAGAGCCGCTGGTATTTATCAAAGCGCCAAACACC
+TTTACCGAACATCACCAAACGTCGGTGCGCCCGAACAACGTCGAATATATGCACTACGAA
+GCCGAGCTGGTCGTGGTGATTGGCAAAACGGCGCGTAAGGTGAGCGAAGCCGAAGCCATG
+GAGTATGTGGCCGGTTACACCGTCTGTAACGACTACGCGATCCGCGACTATCTGGAAAAC
+TACTACCGTCCGAATCTGCGGGTAAAAAGCCGCGACGGCCTGACGCCGATAGGCCCGTGG
+ATTGTGGATAAAGAGGCGGTTTCTGATCCGCACAACCTGACGTTACGCACCTTTGTCAAC
+GGTGAGCTGCGGCAGGAAGGGACGACCGCCGATCTGATCTTCAGCATCCCGTTCCTGATT
+TCTTATCTGAGCGAATTTATGACGTTGCAACCGGGCGACATGATTGCCACCGGTACGCCG
+AAAGGGCTGTCCGATGTGGTGCCGGGGGATGAAGTTGTCGTTGAAGTAGAAGGCGTGGGT
+CGCCTGGTTAACCGAATCGTCAGTGAGGAGAGCGCAAAATGAATGAAAAATGCTTTCAAA
+GACGCGTTAAAAGCGGGGCGCCCGCAAATCGGTTTGTGGCTGGGGCTTGCCAACAGTTAC
+AGCGCTGAACTGTTAGCGGGCGCCGGCTTCGACTGGCTACTGATTGACGGTGAACACGCG
+CCAAACAACGTGCAGACGGTGTTGACCCAGTTGCAGGCGATTGCGCCTTATCCCAGCCAG
+CCGGTGGTGCGTCCGTCATGGAACGATCCGGTACAGATTAAGCAACTGCTCGACGTCGGC
+GCGCAAACGCTGCTGATACCGATGGTGCAGAATGCCGATGAAGCGCGAAACGCCGTGGCG
+GCTACGCGTTATCCGCCTGCCGGTATTCGCGGCGTGGGCAGCGCGCTGGCGCGGGCATCG
+CGCTGGAATCGCATTCCGGACTATCTCCACCAGGCCAACGACGCCATGTGCGTACTGGTG
+CAGATTGAAACGCGTGAGGCGATGAGCAATCTGGCGTCAATTCTCGACGTGGATGGCATT
+GACGGCGTGTTTATTGGCCCGGCGGATCTCAGCGCCGATATGGGCTTTGCCGGCAATCCG
+CAGCACCCGGAAGTGCAGGCGGCGATTGAGAACGCCATCGTGCAGATACGCGCGGCGGGG
+AAAGCGCCGGGGATTCTGATGGCCAATGAAGCACTGGCGAAACGTTATCTGGAACTGGGG
+GCGCTATTTGTCGCCGTCGGCGTTGACACCACGCTGCTGGCGCGCGGAGCGGAGGCGCTG
+GCGGCGCGCTTTGGCGCAGAAAAAAAACTGTCCGGTGCGTCCGGCGTCTATTAAATGCAT
+GATTCATTAACCATCGCCTTGCTTCAGGCGCGCGAAGCGGCAATGACCTATTTCCGCCCC
+ATCGTTAAAAGCCACAATCTGACCGACCAGCAATGGCGCATTGTGCGAATCCTGGCCGAT
+AGCCCCTCTATGGATTTTCACGAGCTGGCCTTTCGTACCTGTATTTTGCGTCCAAGTCTG
+ACCGGAATATTGACGCGCATGGAGCGAGACGGACTGGTGTTGCGACTCAAGCCGGTTAAC
+GATCAGCGTAAGTTATATGTCATGTTGACGGAGCAGGGACAAACGTTGTACGCCCGTGCC
+CGGAGCGAGGTAGAAGAGGCTTATCGAAAAATTGAGGCCGATTTCACGCCCGAAAAAACA
+CAGCAATTGATGCTGCTGCTGGACGATCTTATTGCTCTGGGGCGCCAGCATCCTGATAGC
+GAAGCGGAAGCATAGATGAGCGACACATCATCTGCACTTCCGGAAAGCCCCGAGTCTGTC
+GGTTCGCACAACGCGCTCAGCACGGGTCAACAAACCGTCATAAATAAACTGTTCCGCCGA
+CTGATCGTATTTTTATTCGTGTTGTTTATCTTCTCGTTTTTAGACCGTATCAACATCGGT
+TTTGCCGGGTTGACGATGGGGCAGGATCTGGGGTTAAGCGCCACCATGTTTGGTCTTGCC
+ACGACGCTGTTTTACGCCACCTACGTCATTTTCGGCATTCCCAGCAACGTGATGTTGAGC
+ATCGTCGGCGCCCGCCGCTGGATTGCGACCATTATGGTGCTATGGGGCATTGCATCTACC
+GCCACGATGTTCGCGGTGGGACCGAAAAGCCTGTATGTGCTGCGAATGCTGGTGGGCATT
+ACCGAAGCGGGCTTTTTGCCAGGAATATTGCTCTATTTAACCTACTGGTTCCCGGCATTT
+TTCCGCGCCCGCGCCAACGCATTATTTATGATTGCCATGCCGGCCACTACCGCGTTGGGG
+TCAATTGTCTCCGGCTATATTTTATCGCTGGACGGCATATTCAATCTGCATGGATGGCAG
+TGGTTATTCCTGTTGGAAGGATTTCCGTCAGTTTTGTTAGGCATTATGGTCTGGTTTTAC
+CTGGATGATACCCCGGCAAAAGCCAAATGGCTGACGGCAGAGGATAAAAAATGTTTGCAG
+GAGATGATGGATAATGATCGCCTGACGCTGGTTCAGCCTGAGGGGGCCATCAGCCATAAC
+GCCATGCAGCAGCGTAGCCTGTGGCGCGAAGTATTCACGCCAATTGTACTGATGTATACG
+CTGGCCTATTTTTGCCTTACCAATACGCTTAGCGCCATTAGTATCTGGACGCCGCAAATC
+CTGAAAAGTTTTAATGAAGGCAGCAGCAATATCACCATCGGCCTGCTGGCGGCGATCCCG
+CAGATTTGTACTGTTCTGGGCATGATTTACTGGAGCCGCCATTCGGACAAACATCAGGAG
+CGTAAACACCACACTGCGTTACCGTTCCTGTTTGCCGCCGCGGGCTGGCTGCTGGCGTCG
+GCGACCGACCGTAACCTGATCCAGCTCCTGGGGATCGTGATGGCATCCACGGGTTCCTTT
+AGCGCGATGGCGATCTTCTGGACCACGCCGGATCAGTCGATCAGTTTACGCGCCAGGGCG
+ATAGGCATTGCGGTCATCAATGCCACCGGCAATATTGGCTCCGCGCTCAGCCCGGTTATG
+ATTGGCTGGCTAAAAGATATCACTGGTAGCTTCAATAGCGGACTCTGGTTTGTCGCTTCT
+CTGTTAGTCGTCGGCGCCGCCATTATCTGGCTCATTCCCATGAAAGCATCGCGTCCGCGC
+GCCACCCCTTGAATGGGCAAGTTAGCGTTAGCAGCAAAAATTACCCACGTGCCGTCGATG
+TATCTTTCTGAACTGCCAGGAAAAAATCACGGTTGTCGTCAGGCAGCCATTGATGGGCAT
+ATTGAAATTGGCAAGCGTTGCCGCGAAATGGGCGTTGACACCATTATCGTATTCGACACC
+CACTGGCTGGTGAATAGCGCTTACCACATTAATTGTGCCGACCATTTCCAGGGCGTCTAT
+ACCAGCAACGAATTGCCGCACTTTATTCGCGACATGACCTATGACTATGACGGTAATCCG
+GCGCTCGGCCATCTGATCGCCGACGAGGCGGTCAAACTGGGCGTGCGCGCCAAAGCGCAC
+AACATCCCGAGCCTGAAGCTGGAGTATGGCACGCTGGTGCCGATGCGCTACATGAACAGC
+GACAAGCACTTCAAAGTGGTCTCCATCTCGGCGTTCTGCACTGTGCATGATTTTGCCGAC
+AGCCGCAAACTGGGCGAAGCCATTCTCAAGGCGATTGAGAAATATGACGGTACCGTAGCG
+GTATTCGCCAGTGGTTCTCTGTCGCACCGTTTTATTGACGACCAACGGGCGGAAGAGGGG
+ATGAACAGCTACACCCGCGAGTTCGATCATCAAATGGACGAGCGCGTGGTCAAGCTGTGG
+CGCGAAGGCAAATTCAAGGAGTTTTGCACCATGTTGCCGGAGTACGCCGACTACTGCTAC
+GGCGAAGGCAACATGCACGACACGGTCATGCTACTGGGAATGCTGGGGTGGGACAAATAC
+GACGGCAAGGTGGAGTTCATCACCGACCTGTTCGCCAGCTCCGGTACCGGCCAGGTAAAC
+GCTGTTTTCCCGCTGCCTGCGTAAATGAAGAAAATAAATCATTGGATTAACGGCAAAAAC
+GTTGCAGGTAACGACTACTTCCAGACCACTAACCCGGCGACCGGTGATGTGCTGGCGGAA
+GTAGCCTCCGGCGGTGAAGCAGAAGTGAACCAGGCTGTCGCGGCGGCAAAAGAGGCGTTC
+CCGAAATGGGCCAACCTGCCGATGAAAGAGCGCGCGCGCCTGATGCGCCGCCTTGGCGAC
+CTGATTGACCAGCATGTGCCGGAAATCGCGGCGATGGAAACCGCCGACACCGGCCTGCCT
+ATTCACCAGACTAAAACGTGCTGAGTGCTGATCCCGCGCGCCTCGCATAACTTCGAATTC
+TTCGCCGAAGTGTGCCAGCAGATGAACGGCAAGACCTATCCGGTTGACGATAAAATGCTC
+AATTATACGCTGGTGCAGCCCGTCGGCGTCTGCGCGCTGGTGTCGCCGTGGAACGTGCCG
+TTTATGACCGCGACTTGGAAAGTTGCGCCGTGCCTGGCGCTGGGTAACACCGCGGTGCTC
+AAAATGTCCGAGCTGTCGCCGCTGACTGCCGACAGGCTGGGCGAGCTGGCACTGGAGGCA
+GGAATTCCGGCAGGCGTGCTGAACGTGGTGCAGGGCTACGGCGCGACGGCGGGCGATGCG
+CTGGTACGCCACCATGACGTGCGTGCGGTGTCGTTTACCGGCGGTACCGCCACCGGTCGC
+AATATCATGAAAAATGCCGGGCTGAAAAAATACTCGATGGAGCTGGGCGGCAAATCGCCG
+GTGCTGATTTTTGAAGACGCCGACATTGAGCGCGCGCTGGACGCCGCGCTGTTCACCATC
+TTCTCGATCAACGGCGAACGCTGCACCGCTGGGTCGCGCATCTTTATCCAGCAGAGCATT
+TACCCTGAGTTCGTGAAGCGCTTTGCCGAACGCGCGAATCGCCTGCGTGTCGGCGATCCG
+ACCGACCCGAACACCCAGGTCGGCGCGCTGATTAGCCAACAGCACTGGGAGAAAGTCTCC
+GGTTATATCCGCCTCGGCATTGAAGAGGGGGCAACGCTGCTGGCGGGCGGTGCGGAAAAA
+CCCACTGACCTGCCTGCGCATCTGAAAGGCGGTAACTTCCTGCGCCCAACCGTGCTGGCC
+GATGTCGACAACCGTATGCGCGTTGCGCAGGAAGAGATCTTTGGGCCGGTCGCCTGCCTG
+CTGCCATTCAAAGACGAAGCGGAAGGGTTACGTTTGGCGAACGATGTGGAATACGGTCTG
+GCCTCTTATATCTGGACCCAGGACGTGAGCAAAGTGTTGCGCCTGGCGCGTGGGATTGAA
+GCCGGCATGGTCTTCGTCAACACCCAGAACGTCCGCGACCTGCGCCAGCCGTTCGGCGGC
+GTGAAAGCCTCCGGTACCGGGCGCGAAGGCGGCGAATATAGCTTCGAAGTGTTTGCGGAA
+ATGAAAAACGTCTGCATCTCAATGGGCGACCATCCTATCCCAAAATGGGGAGTTTGAATG
+CCGCACTTTATTGCTGAATGTACTGAAAATATTCGCGAGCAGGCTGATTTACCAAGCCTG
+TTCAGCAAGGTAAACGAGGCGCTGGCCGCCACCGGGATTTTCCCCATCGGCGGTATCCGC
+AGTCGCGCCCACTGGCTGGATACCTGGCAGATGGCTGACGGTAAGCATGATTACGCGTTT
+GTGCATATGACGCTGAAAATCGGCGCCGGGCGCAGCCTGGAGAGCCGTCAGGAAGTCGGC
+GAAATGCTGTTTGGGCTGATTAAAGCCCACTTCGCCGACCTGATGGAGAACCGCTATCTG
+GCGCTGTCGTTTGAGATTGCCGAGTTACATCCAACGCTCAATTACAAACAAAACAACGTA
+CACGCGTTATTTAAATAGATGCTCGATAAACAGACCCATACCCTGATCGCTCAGCGACTT
+AATCAGGCTGAAAAACAGCGTGAACAGATTCGCGCAGTGTCGCTGGATTATCCCAACATC
+ACTATTGAAGATGCCTATGCCGTACAGCGTGAATGGGTCAATATCAAGATTGCCGAAGGG
+CGCACGCTCAAAGGCCACAAAATCGGCCTGACCTCAAAAGCGATGCAGGCCAGCTCGCAA
+ATCAGCGAACCGGATTACGGCGCGCTGCTTGACGATATGTTCTTCCATGACGGCGGAGAT
+ATCCCCACCGACCGTTTTATCGTCCCGCGTATTGAAGTGGAGCTGGCGTTCGTGCTGGCG
+AAACCGCTGCGCGGCCCTCACTGCACGCTGTTCGACGTCTACAACGCCACGGATTATGTG
+ATTCCGGCGCTGGAACTGATTGACGCCCGCAGCCACAACATCGACCCGGAAACCCAGCGC
+CCGCGCAAAGTGTTCGACACCATTTCCGACAACGCCGCCAACGCCGGGGTGATCCTCGGT
+GGTCGCCCCATCAAACCAGACGAGCTGGATCTGCGCTGGATCTCCGCGCTGCTCTATCGC
+AACGGCGTGATCGAAGAAACCGGCGTCGCCGCAGGCGTGCTGAATCATCCGGCCAACGGC
+GTGGCGTGGCTGGCGAACAAGCTTGCCCCCTACGATGTCCAGCTTGAAGCCGGGCAGATC
+ATCCTCGGCGGCTCGTTCACCCGCCCGGTGCCGGCGCGCAAGGGCGACACCTTCCATGTC
+GATTACGGCAACATGGGCGCGATCAGTTGCCGGTTTGTGTAAATGAGCTCTGTACCCGCG
+CCGCGTGAATATTTTCTTGACTCTATCCGCGCATGGCTGATGTTGTTAGGGATTCCCTTT
+CATATCTCGTTGATCTATTCCACTCACAGTTGGCATGTCAATAGCGCCGCGCCATCGTGG
+TGGCTAACCCTGTTTAACGATTTTATCCACGCTTTTCGTATGCAGGTGTTTTTTGTTATT
+TCTGGTTATTTTTCGTACATGTTATTTTTACGTTATCCATTAAAACACTGGTGGAAAGTA
+CGGGTAGAACGTGTGGGTATTCCCATGCTTACCGCAATCCCTTTGCTTACCTTGCCGCAA
+TTTATCCTGTTGCAATATGTCAAAGAGAAAACAGAGAACTGGCCTACACTCTCTGCCTAT
+GAAAAATATAATACGTTAGCGTGGGAACTCATTTCACATCTGTGGTTTTTACTGGTGCTG
+GTGATATTAACCACCGTCAGCATCGGGATTTTTACCTGGTTCCAAAAAAGGCAGGAAACA
+AGCAAGCCTCGTCCCGCCGCTATTTCGCTGGCCAAACTTTCGCTTATTTTTTTCCTGCTG
+GGGGTGGCGTACGCTGCTATCAGGCGCATTATATTCATCGTATATCCGGCAATCCTCAGT
+GACGGCATGTTCAATTTTATTGTGATGCAAACGCTATTTTATGTGCCGTTTTTTATTCTC
+GGCGCGTTGGCCTTCATTCACCCCGATCTGAAAGCGCGCTTCACCACGCCCTCACGCGGA
+TGCACTTTAGGCGCTGCCGTTGCTTTTATCGCGTATCTGCTGAATCAACGTTATGGGAGC
+GGCGACGCCTGGATGTACGAAACCGAATCCGTGATTACGATGGTAATGGGGCTATGGATG
+GTGAACGTGGTATTTTCACTGGGGCATCGCTTGTTAAACTTTCAGTCCGCGCGTGTCACC
+TATTTCGTGAATGCTTCGCTGTTTATTTATCTGGTGCATCATCCCTTAACGCTTTTCTTT
+GGCGCGTATATTACACCGCATATCTCCTCCAACCTGATCGGGTTCTTGTGCGGGCTGATA
+TTTGTTATGGGTATTGCGTTAATTCTGTATGAAATTCATTTACGCATCCCGCTCCTGAAA
+TTTCTCTTTTCAGGTAAACCGCCGGTAAAACAAGAAAGCCGCGCCGCGATCGGGTAGATG
+AAACATAAACGACAAATGATGAAAATGCGTTGGTTGGGCGCAGCTATTATGTTAACGCTC
+TACGCATCATCGAGCTGGGCGTTCAGTATTGATGACGTGGCAAAACAAGCTCAATCTTTA
+GCCGGGAAAGGCTATGAGGCGCCTAAAAGCAACTTGCCCTCCGTTTTCCGCGACATGAAA
+TATGCGGATTATCAGCAGATCCAGTTTAACAGCGATAAAGCCTACTGGAACAACTTAAAG
+ACCCCTTTTAAGCTCGAATTTTACCATCAGGGGATGTACTTCGATACGCCGGTCAAGATT
+AACGAAGTGACGGCGACGACGGTCAAAAGAATCAAATACAGCCCGGATTACTTCAATTTT
+GGCAATGTTCAGCACGATAAAGACACGGTAAAAGATTTAGGCTTCGCCGGGTTCAAAGTC
+CTGTACCCCATTAACAGTAAAGATAAGAACGACGAAATCGTCAGTATGCTTGGCGCCAGC
+TATTTCCGCGTTATCGGCGCAGGCCAGGTGTATGGCTTATCTGCGCGCGGCCTGGCGATT
+GATACCGCCTTACCATCTGGTGAAGAGTTTCCCCGCTTTCGCGAGTTCTGGATTGAGCGT
+CCAAAACCCACCGATAAGCGTTTGACCGTCTATGCATTACTGGATTCTCCGCGCGCGACC
+GGCGCTTACCGTTTTGTGATCATTCCTGGCCGCGATACCGTGGTGGACGTGCAGTCAAAA
+GTCTATCTGCGCGATAAGGTGGGCAAGCTGGGCGTTGCGCCATTAACCAGTATGTTCCTG
+TTTGGGCCAAACCAGCCGTCGCCGACGACCAACTATCGTCCGGAATTGCATGACTCGAAC
+GGCTTATCCATTCATGCGGGTAATGGCGAGTGGATTTGGCGTCCGCTGAACAATCCAAAA
+CACCTCGCTGTGAGCAGCTATGCGATGGAAAACCCTCAGGGATTCGGCCTGTTGCAGCGT
+GGTCGCGAGTTCTCGCGCTTTGAAGATTTAGACGATCGCTATGACCTGCGTCCAAGCGCC
+TGGATTACCCCGAAAGGCGACTGGGGCAAAGGTAAGGTTGAACTGGTTGAAATTCCGACC
+AATGATGAAACCAACGATAACATCGTCGCTTACTGGACTCCGGATCAACTGCCGGAACCG
+GGTAAAGAGATGAACTTCAAGTACACTCTGACCTTCAGCCGCGATGAAGATAAACTTCAT
+GCGCCGGATAATGCCTGGGTGCTGCAAACACGCCGCTCAACGGGCGACGTTAAACAGTCG
+AATCTGATTCGCCAGCCCGACGGCACTATTGCCTTTGTGGTGGATTTCGTTGGCGCCGAC
+ATGAAAAAACTGCCGCCGGATACGCCCGTCGCTGCACAAACCAGCATTGGCGATAACGGT
+GAAATCGTTGACAGTAATGTACGCTATAACCCAGTCACTAAAGGCTGGCGTTTAATGCTG
+CGCGTGAAAGTCAAAGACGCGAAGAAAACCACGGAAATGCGTGCCGCATTGGTGAATGCC
+GATCAGACGCTAAGTGAAACCTGGAGCTACCAGTTACCTGCCAATGAATAAatgaataaa
+acaactgagtatattgacgcactgctgctttctgaacgtgagaaagcggcattgccgaaa
+actgacatccgcgccgtgcatcaggcgctggatgccgagcatcggacttactcgcgagaa
+gacgattcaccgcagggttccgtaaaagcccgccttgaacacgcctggccggattcattg
+gcgaaggggcagttaattaaagatgatgaagggcgcgatcagttgcaggctatgccaaaa
+gcgacgcgctcttcgatgtttcctgatccctggcgaaccaacccggttggccgtttctgg
+gatcgcctgcgtgggcgggatgttacgccgcgctatgtttctcgtctgacaaaagaagag
+caggcgagtgagcaaaaatggcgtaccgtcggcactatacgccgctatattttgttaatt
+ttgactctggcgcaaaccgtcgttgcgacctggtatatgaagaccattctgccctatcag
+ggatgggcgctcatcaatcctattgatatggtggggcaggatatttgggtctcctttatg
+cagctcctgccctacatgctgcataccggtatcctgattttgtttgccgtgctgttctgc
+tgggtgtctgccggattctggactgcgctgatgggcttcctgcaactgcttatcgggcgc
+gataagtacagtatctccgcgtctacggttggcgatgagcccctcaatccggaacaccag
+acggcgctgatcatgcctatctgtaatgaagacgttagccgcgttttcgccggtctgcgc
+gcgacctgggagtccgttaaagctacaggcaacgccgcgcattttgacgtctatatcctt
+agcgatagttataacccggatatttgcgtggcggagcaaaaggcgtggatggagctcatc
+gcggaagtgcagggcgaaggccatattttttaccgtcgccgccgccgccgtatgaaacgc
+aaaagcggcaatattgacgatttttgccgccgctggggcaatcagtacagctatatggtg
+gtgctggacgcggactcagtgattagcggcgagtgtctgagcgggctggtgcgcctgatg
+gaagcgaaccctaacgccgggattatccagtcttcgccgaaagcgtcggggatggatact
+ctgtatgcccgctgccaacagtttgcgacccgtgtttatggaccgctgtttaccgccggg
+ctgcacttctggcagttgggggattcgcactactgggggcacaatgccattatccgcgtg
+aagccgtttatcgagcactgcgctctggcgccgctgccgggagaaggttcgttcgccgga
+tcgattctttcccacgactttgttgaggcggcgctaatgcgtcgggcagggtggggcgtc
+tggattgcctacgatctccccggttcctatgaagagctgccgccaaacctgctggatgag
+cttaaacgcgaccgccgctggtgtcacggcaacctgatgaactttcgtctgttcctggtg
+aaaggaatgcacccggtgcatcgtgccgtgttcctgaccggggtaatgtcatacctgtcc
+gcgccgttatggtttatgttccttgcgctttctaccgcgctgcaggtcgttcatgcgtta
+acagagccgcaatatttccttcatccgcgccagctttttccggtctggccgcagtggcgt
+ccggaactggcaatcgcgctgtttgcgtcaacgatggtgctgctgttcctgccgaagctg
+ctcagtattatgctgatctggtgtaaaggcaccaaagagtatggcggtttctggcgcgtt
+acgctgtcgctattgctggaagttctgttctccgtgttgctggcgccggtgcgtatgctg
+tttcataccgtgtttgtggtcagtgcgttcctcggctgggaagtggtctggaactcaccg
+caacgcgacgatgattctacgccttggggagaagcctttatgcgtcacggctctcaactg
+ctgctggggctggtctgggcggttggtatggcgtggctggatttacgctttctgttctgg
+ctggcgccgattgtcttttcgcttattctgtcgccatttgtttcggtgatctccagtcgt
+tcaacggtaggattacgcaccaatcgctggaagctgttcctgatcccggaagagtattcg
+ccgcctcaggtgttggtcgatactgataaatatctggagatgaatcgccgccgtattctg
+gacgatggctttatgcatgcggtttttaacccgtcgcttaatgcgctggcgaccgcgatg
+gccaccgcgcgtcaccgcgccagtaaggtgctggaaatagcccgcgatcgtcatgtggag
+caggcgctaaacgaaacgccggataaactgaaccgcgatcggcgtctggttttgctcagc
+gatccggtgacgatggcgcgttttcactatcgggtctggaatgcgccagagagatactct
+tcctgggtaaaccattatcagtctctcgtcctgaatccgcaggcgttgcagggacgaaca
+tcgtcagcgggataaatgtcgcgcgtctcgnnggcgaggaacctgggtaaatattttctt
+ctcatcgataacatgttagtggtgctgggtnntttcgtcgtcttcccgctcatctctatt
+cgctttgtcgatcaaatggggtgggctgccnnaatggtagggatcgcgctcggcctgcgt
+cagtttattcaacaaggtctgggcatttttnncggcgccatcgccgatcgctttggcgcg
+aaaccgatgattgtcaccggtatgctgatgnncgccgcaggctttgccaccatgggtatc
+gcgcatgagccctggctcttgtggttttccnnctttctttccggtctcggcggtacgctt
+ttcgacccgccgcgttcagcgctggtggtcnnattaattcgtccggagcaacggggccgc
+ttcttctctctgttgatgatgcaggacagcnngggcgcggtgattggcgcgctgctggga
+agctggttgctacaatacgattttcgcctgnnctgcgcgacgggcgctattttgttcata
+ttatgcgcccttttcaacgcatggctgcttnnggcctggaagctatcaacggccagaacg
+ccggtgcgtgaaggaatgcgccgcgtcatgnncaataaaaggtttgtcacctacgtgctg
+acgctggcgggctactatatgctggcggtannggtcatgttaatgctgccgattatggta
+aacgatatcgccggttcgcctgctgccgtgnnatggatgtacgctattgaggcgtgtctc
+tcgctgacgttgctctacccgattgcccgcnngagcgaaaagcgttttcggctggagcat
+cggctgatggccggtttgctcgtcatgtcgnngagcatgctccccatcgggatggtgggc
+aatttacagcagctttttacgcttatttgcnntttctacatcggctcggttatcgccgaa
+ccggcgcgcgaaacgctcagcgcgtcgcccnnggacgcgagggcgcggggaagctatatg
+ggctttagccgtctgggattagccattggcnncgcgattagttatatcggcggcggctgg
+ttgtttgatatgggtaaagcgcttgcgcagnntgaactaccgtggatgatgctcggtatt
+atcggctttatcacctttttggctttaggcnngcaatttagtcataagcgcacgccgcgc
+cggatgctggaacccggcgcctgaatgaccaagtatgccacgctggaagaagctatcgat
+gcagcccgggaagaatttctggctgaccatcaaggcctcgaacaagacgaagcgaatgtg
+cagcagttcaacgttcagaaatatgtactgcaggatggggacatcatgtggcaggtcgaa
+tttttcgccgatgaaggtgaagatggcgaatatctgccgatgctgagtggtgaagccgca
+cagagcgtgtttgacggcgattatgatgagaaagagatccgccaggaatggcaggaagag
+aatactttgcatgaatgggatgaaggggaataccagcttgaacccccgcttgataccgag
+gaaggccgtactgcggcagacgaatgggatgagcgttaaATGTCACTATTAGCCAGGCTG
+GAACAAAGTGTACACGAAAACGGTGGGCTGATTGTCTCATGCCAACCGGTACCAGGCAGC
+CCTATGGATAAACCTGAAATTGTGGCTGCAATGGCACAGGCAGCGGCTTCGGCGGGTGCG
+GTCGCTGTGCGCATTGAAGGCATTGAGAATCTGCGGACTGTTCGTCCCCATCTTTCTGTT
+CCTATTATTGGGATAATTAAACGTGACCTTACAGGGTCGCCAGTCCGTATCACTCCATAT
+TTACAGGATGTTGACGCCCTGGCGCAGGCAGGTGCCGATATTATCGCTTTTGATGCCTCA
+TTCCGCTCTCGCCCGGTTGATATTGATAGTTTACTGACACGTATTCGCCTGCATGGATTA
+CTGGCGATGGCAGACTGTTCAACCGTGAATGAAGGCATAAGTTGCCATCAGAAAGGAATC
+GAATTCATTGGTACAACACTGTCTGGCTATACCGGTCCCATCACGCCGGTTGAGCCAGAT
+TTGGCAATGGTGACACAACTGAGTCATGCAGGTTGTCGTGTTATTGCCGAGGGGCGCTAT
+AACACGCCTGCACTGGCGGCCAATGCTATTGAGCATGGTGCCTGGGCAGTTACCGTTGGT
+TCCGCTATCACCCGTATCGAGCATATCTGTCAGTGGTTCAGTCACGCAGTAAAACGCTGA
+ATGAAAAATTTTAAGAAAATGATGACGCTAATGGCGCTATGTTTATCAGTTGCTATCACC
+ACATCAGGATATGCAACCACGCTTCCTGATATACCAGAACCACTGAAAAATGGTACTGGC
+GCTATTGATAATAATGGCGTGATTTATGTCGGCTTAGGTACCGCAGGGACATCCTGGTAT
+AAAATTGATCTTAAAAAGCAACATAAAGACTGGGAGCGTATAAAGTCGTTTCCTGGTGGA
+GCTCGTGAGCAATCCGTGTCGGTATTTTTAAATGATAAGCTGTATGTTTTTGGTGGCGTA
+GGGAAAAAAAACAGTGAATCACCGTTGCAGGTTTATAGCGATGTGTACAAATACTCACCG
+GTGAAAAATACATGGCAAAAAGTTGATACTATATCTCCAGTTGGATTAACAGGGCATACG
+GGAGTAAAATTAAACGAAACGATGGTACTTATTACCGGAGGGGTTAATGAGCATATCTTT
+GATAAGTATTTTATTGATATAGCGGCTGCGGATGAAAGTGAAAAAAATAAAGTCATCTAT
+AATTATTTTAATAAACCTGCCAAAGATTATTTTTTTAATAAAATCGTATTTATCTACAAT
+GCTAAAGAGAACACATGGAAGAATGCCGGTGAGCTGCCAGGCGCGGGGACGGCAGGATCG
+TCATCGGTAATGGAAAATAATTTCTTGATGCTGATTAATGGTGAGCTCAAACCGGGTTTA
+CGTACCGATGTGATTTACCGCGCCATGTGGGATAACGATAAGCTAACATGGTTGAAGAAC
+AGCCAGTTACCGCCATCGCCTGGAGAACAACAGCAGGAAGGGTTGGCCGGAGCATTTTCG
+GGCTATAGCCACGGTGTCCTGCTTGTCGGTGGTGGCGCGAATTTTCCGGGAGCAAAACAA
+AATTATACTAATGGAAAGTTTTATTCCCACGAAGGGATAAATAAAAAATGGCGAGATGAA
+GTCTATGGTTTGATTAATGGCCATTGGCAATATATGGGTAAAATGAAACAACCTCTCGGC
+TATGGTGTATCAGTAAGTTATGGTGATGAAGTTTTCCTTATTGGTGGTGAAAATGCTAAA
+GGGAAACCTGTTTCGTCTGTAACCTCCTTTACCATGCGTGATGGTAATTTATTAATAAAA
+TAAGTGATAGCAAAATTCTTCCCGTGGTATAGCGAGATAACACGTCCACAAAAAAATGCT
+TTATTTTCAGCATGGCTGGGTTACGTTTTTGATGGCTTCGACTTTATGCTGATTTTCTAC
+ATTATGTATCTGATCAAGGCTGACTTAGGATTGACAGATATGGAGGGCGCATTCCTTGCC
+ACAGCGGCCTTTATTGGGCGACCATTTGGCGGGGCGCTATTTGGTCTGCTGGCAGACAAA
+TTTGGCCGTAAGCCGTTAATGATGTGGTCGATAGTTGCCTATTCTGTAGGTACAGGGTTA
+AGTGGCCTGGCTTCCGGTGTAATTATGCTGACGCTTAGTCGTTTTATTGTCGGTATGGGG
+ATGGCGGGGAAGTATGCTTGCGCTTCTACTTATGCCGTGGAAAGTTGGCCAAAGCATTTA
+AAATCTAAAGCGAGCGCATTTCTGGTTTCAGGTTTCGGTATTGGTAACATCATAGCAGCC
+TATTTTATGCCGTCATTTGCCGAAGCGTATGGTTGGCGTGCTGCTTTTTTTGTCGGTTTG
+CTACCCGTTCTTTTAGTAATCTACATCCGGGCCAGGGCTCCTGAATCTAAAGAGTGGGAA
+GAAGCCAAACTCAGTGGTCTCGGAAAGCATTCACAAAGTGCCTGGTCAGTTTTCTCTTTG
+TCAATGAAAGGGCTATTTAATCGAGCTCAATTTCCACTGACATTATGTGTATTTATTGTT
+CTGTTCTCTATTTTCGGCGCAAACTGGCCGATCTTTGGTCTACTGCCTACATATTTGGCG
+GGAGAGGGCTTTGATACGGGCGTGGTCTCTAATTTAATGACGGCGGCGGCATTCGGCACT
+GTATTGGGAAATATCGTTTGGGGTCTGTGCGCAGATAGAATTGGTTTGAAGAAAACGTTC
+AGCATTGGTCTTCTCATGTCCTTTTTATTCATTTTCCCGTTATTCAGAATTCCGCAAGAT
+AATTATTTACTGCTGGGCGCATGTTTATTCGGTTTAATGGCGACTAACGTAGGTGTTGGC
+GGGCTGGTTCCCAAATTTCTCTACGACTACTTTCCTCTTGAGGTTCGTGGTTTGGGTACC
+GGGCTTATTTATAATCTTGCTGCGACATCAGGCACATTCAATTCAATGGCGGCGACCTGG
+CTTGGAATAACAATGGGGCTAGGCGCTGCGCTAACGTTCATTGTTGCTTTCTGGACCGCA
+ACAATTCTACTCATTATTGGCCTATCCATTCCGGATAGACTAAAAGCACGTCGTGAAAGG
+TTTCAGTCAACAAAAGAATTTTAAATGAAAAAGTATCTTGCTTTCGCCGTTACGCTGCTG
+GGTATGGGTAAAGTCATCGCCTGTACTACCCTTTTGGTAGGCAATCAGGCTTCGGCTGAC
+GGCTCCTTTATTATCGCGCGCAACGAGGATGGCTCGGCAAATAACGCCAAGCATAAGGTT
+ATTCATCCCGTCGCGTTTCATCAACAAGGCGAGTATAAAGCACATCGCAACAATTTTAGC
+TGGCCGCTTCCGGAGACAGCGATGCGCTATACGGCGATTCATGACTTTGATACTAACGAT
+AACGCCATGGGTGAAGCCGGTTTCAATTCGGCGGGCGTCGGAATGAGCGCAACGGAAACC
+ATTTACAACGGCAGAGCGGCGCTGGCTGCCGATCCTTACGTGACAAAAACGGGAATCACG
+GAAGACGCCATTGAGTCCGTGATCCTGCCAGTGGCGCAATCGGCGCGTCAGGGCGCCAAA
+TTACTGGGAGATATTATTGAACAAAAAGGCGCGGGCGAAGGTTTCGGCGTCGCGTTTATT
+GATAGCAAAGAGATATGGTATCTGGAGACGGGAAGCGGACATCAATGGCTGGCAGTACGA
+CTTCCGGCAGATAGCTATTTCGTTTCCGCCAATCAGGGACGTTTACGCCATTACGATCCG
+AATGATAACGCGAATTATATGGCGTCACCAACGTTAGTAAGCTTTGCGAAAAAGCAGGGA
+TTATATGATCCGGCCCGCGGCGAATTCGACTTTCATCAAGCCTATTCGCAGGATAACAAA
+AACGATACCACCTATAATTATCCGCGCGTCTGGACGCTACAACACCAGTTTAATCCGCAT
+CTGGATACGGTCGTTAGCGAAGGGGAAACATTTTCTGTTTTTTTAACGCCAATAACGAAG
+ATCAGCGTGGCGGCAGTAAAAAACGCGTTACGCAATCACTATCAGGGAACGTCGCACGAC
+CCTTATGCCAGTCATAATCCACAAGAACCATGGCGACCTATATCCGTTTTTCGTACCCAG
+GAGTCACATATTTTACAGGTCAGACCGAAATTACCGCAGGCTATCGGCAACGTAGAATAC
+ATCGCCTATGGAATGCCATCTCTTAGCGTCTATCTCCCCTATTACCAGGGGATGCGTCAT
+TATCAACCCGGAGATGATAAAGGAACCGATCGGGCGAGCAACGACTCTACCTACTGGACA
+TTCCGCACGCTGCAAACACTGGTTATGCAAGACTACAATACGTTTGCGCCAGATGTGCAA
+CATGCCTGGAAAACATTTGAACAGCAAACAGCTAAGCAACAGTATAAGATGGAGCAGAGC
+TATCTGAGATTATATGCGTCGCATCCGAAAGAAGCACAACGCTTACTGCAAAATTTTGAA
+GATAAAACGATGCAAAATGCGCAGACGCTCGCCCGTCGCCTGACCAATAATATTATTACG
+ACAATGACTTACCGCACAGATATGAAATATCACTTTTCAAGTACGCAGCCATAAATGGGA
+AGACAAAAAGCAGTGATCAAAGCTCGTCGTGAAGCAAAGCGTGTGTTGAGACGAGATTCG
+CGTAGTCATAAGCAACGTGAAGAAGAATCGGTCACGTCACTGGTACAGATGGGCGGAGTA
+GAAGCCATTGGCATGGCGCGCGATAGTCGCGATACCTCTCCTGTTAAGGCGCGAAATGAA
+GCACAGGCGCATTATCTGAACGCTATCGACAGTAAACAGCTTATTTTTGCGACCGGCGAA
+GCCGGCTGCGGAAAAACATGGATCAGTGCGGCAAAGGCGGCAGAAGCATTGATTCATAAG
+GACGTCGAGAGGATCATTGTGACGCGTCCGGTATTGCAGGCTGATGAAGATCTTGGTTTT
+TTGCCCGGTGATATCGCTGAAAAATTCGCGCCTTATTTTCGTCCCGTCTACGATGTCCTG
+CTTAAACGGTTGGGCGCGTCCTTTATGCAATATTGTTTGCGCCCGGAAATCGGTAAGGTA
+GAAATTGCCCCGTTCGCCTATATGCGTGGGCGTACTTTTGAAAATGCGGTCGTGATCCTC
+GACGAGGCGCAAAATGTGACTGCGGCGCAAATGAAAATGTTTTTGACGCGATTAGGCGAA
+AATGTCACGGTCATTGTCAATGGCGATATTACGCAATGCGACCTGCCGCGCGGTGTGCGT
+TCCGGGTTGAGTGATGCGTTGGAACGCTTTGAAGAAGATGAAATGGTGGGGATTGTGCAT
+TTCAACAAAGACGACTGCGTGCGCTCGGCGCTTTGTCAGCGAACGCTCCACGCATACAGC
+TAAATGGGAACCACCACGATGGGGGTTAAGCTGGACGACGCCACGCGCGAACGGATCAAA
+ATGGCCGCGTCGCGTATCGATCGCACGCCGCACTGGTTAATAAAACAGGCAATCTTTAGC
+TATCTGGACAAGCTGGAAAATAGCGATACGCTACCGGAGCTACCTGCGCTGTTTGCCGGC
+GCGGCAAATGAAAGCGAGGAGCCGGTCGCGCCGCAGGATGAGCCGCATCAGCCCTTTCTG
+GAGTTTGCCGAACAGATTCTTCCCCAATCCGTCTCTCGCGCCGCCATCACCGCCGCCTGG
+CGCCGCCCGGAAACCGATGCGGTGTCAATGCTAATGGAACAGGCGCGCCTGTCGCCGCCT
+GTCGCTGAGCAGGCGCATAAACTGGCGTATCAACTGGCGGAGAAATTGCGCAATCAAAAA
+TCCGCCAGCGGTCGCGCGGGTATGGTGCAAGGCCTGTTGCAGGAGTTTTCCCTCTCTTCG
+CAAGAAGGCGTAGCGCTGATGTGTCTGGCGGAAGCGCTGCTGCGTATTCCCGACAAAGCT
+ACGCGCGATGCGTTAATTCGCGACAAAATCAGTAATGGCAACTGGCAGTCGCATATTGGC
+CGTAGCCCGTCGCTGTTTGTAAACGCCGCCACCTGGGGGCTGCTCTTTACCGGCCGACTG
+GTCTCAACGCATAACGAAGCCAATCTTTCGCGCTCGCTGAACCGCATTATCGGCAAGAGC
+GGCGAACCGTTAATCCGCAAAGGCGTCGACATGGCGATGCGTTTAATGGGCGAGCAGTTC
+GTGACTGGCGAAACCATTGCTCAGGCGCTGGCGAATGCCCGAAAACTGGAAGAGAAAGGG
+TTCCGCTATTCTTACGATATGCTGGGCGAAGCCGCGTTAACCGCCGCCGATGCGCAGGCC
+TATATGGTCTCTTACCAGCAAGCGATTCATGCCATCGGCAAAGCGTCTAACGGTCGCGGT
+ATTTACGAAGGGCCAGGCATCTCGATTAAGCTGTCCGCCCTGCATCCACGCTATAGTCGC
+GCGCAATACGATCGGGTAATGGAGGAGCTTTATCCGCGCCTGAAATCCCTGACGCTGCTG
+GCGCGCCAGTATGATATCGGTCTCAATATCGACGCCGAAGAGGCGGATCGTCTGGAGATC
+TCGCTTGATCTGCTGGAAAAACTCTGCTTCGAACCCGAACTGGCGGGCTGGAACGGCATT
+GGCTTTGTGATTCAGGCTTACCAGAAACGCTGCCCGCTGGTCATTGATTATTTAGTCGAT
+CTGGCCTCCCGTAGCCGCCGTCGGCTGATGATTCGTCTGGTGAAAGGCGCCTACTGGGAT
+AGCGAGATCAAACGCGCGCAAATGGAAGGGCTGGAGGGCTATCCAGTTTATACCCGCAAA
+GTGTATACCGATGTCTCTTATCTGGCCTGCGCGAAAAAACTGCTCGCCGTCCCTAATCTG
+ATCTACCCGCAGTTCGCGACCCATAACGCTCACACACTGGCGGCGATTTATCATCTGGCC
+GGGCAAAATTACTATCCGGGTCAGTACGAATTCCAGTGCCTGCACGGCATGGGAGAACCG
+CTGTATGAACAGGTCACCGGTAAAGTGGGGGACGGAAAACTTAACCGTCCCTGCCGTATT
+TACGCGCCGGTGGGAACACACGAAACCCTGCTGGCCTATCTGGTACGACGCCTGCTGGAA
+AACGGCGCCAACACCTCTTTTGTCAACCGCATCGCCGATGCCACCCTACCGCTCGATGAA
+CTGGTGGCCGACCCGGTCGAGGCCGTGGAAAAACTGGCGCAGCAGGAAGGTCAGGCTGGC
+ATACCGCATCCAAAAATTCCGCTGCCGCGCGATCTGTACGGCGAAGGTCGGATAAACTCC
+GCCGGACTTGATTTAGCGAATGAACATCGCCTCGCCTCGCTTTCTTCTGCCCTGTTAAGC
+AACGCCATGCAGAAATGGCAGGCCAAACCTGTGCTGGAACAACCGGTGGCCGACGGTGAG
+ATGACGCCGGTTATCAACCCGGCGGAACCGAAAGATATTGTTGGCTGGGGACGCGAAGCG
+ACAGAAAGCGAGGTTGAACAGGCGTTGCAAAACGCGGTCAATCAGGCGCCGGTTTGGTTT
+GCGACGCCGCCGCAAGAACGCGCCGCTATTTTGCAGCGGGCGGCGGTATTGATGGAAGAC
+CAAATGCAGCAGTTGATTGGCCTGTTGGTGCGTGAAGCGGGGAAAACGTTCAGCAACGCC
+ATTGCCGAAGTGCGCGAAGCGGTAGACTTCCTCCATTATTATGCCGGTCAAGTGCGTGAC
+GATTTCGATAACGAAACGCATCGCCCGTTAGGGCCGGTGGTCTGTATCAGTCCGTGGAAC
+TTTCCGCTGGCCATTTTCACTGGCCAAATCGCCGCCGCGCTGGCGGCAGGTAACAGCGTT
+CTGGCGAAACCGGCAGAGCAGACATCGCTGATTGCCGCCCAGGGCATTGCCATTTTGCTG
+GAAGCGGGCGTACCGCCGGGCGTCGTGCAACTGTTGCCGGGACGGGGAGAAACCGTCGGC
+GCCCAGCTTACCGCCGATGCGCGTGTACGCGGCGTGATGTTTACCGGTTCCACGGAGGTC
+GCGACGTTGTTGCAGCGCAACATCGCCACGCGTCTTGACGCCCAGGGGCGCCCTATTCCG
+TTGATTGCGGAAACCGGCGGTATGAACGCTATGATTGTCGACTCTTCCGCGCTCACCGAG
+CAGGTGGTCGTGGATGTGCTGGCTTCCGCCTTCGACAGCGCCGGACAACGCTGTTCCGCG
+CTCCGCGTGCTGTGTTTGCAGGACGATATCGCCGAACATACGCTGAAAATGTTACGCGGC
+GCGATGGCGGAGTGTCGGATGGGGAATCCAGGCCGTCTGACGACCGATATCGGGCCGGTG
+ATCGATAGCGAGGCCAAAGCCAACATTGAACGTCATATCCAGACGATGCGCGCCAAAGGC
+CGCCCGGTTTTCCAGGCCGCGCGTGAAAACAGCGATGACGCGCAGGAATGGCAGACCGGT
+ACGTTTGTTATGCCCACGCTTATTGAGCTGGAAAACTTCGCAGAACTGGAAAAAGAGGTC
+TTCGGGCCCGTGCTGCACGTCGTGCGTTATAACCGTAACCAACTGGCGGAGCTTATCGAA
+CAGATTAACGCTTCCGGCTACGGGCTAACGCTGGGCGTACATACCCGTATTGATGAAACC
+ATTGCGCAAGTCACCGGTTCCGCCCATGTCGGCAACCTGTACGTTAACCGTAATATGGTG
+GGCGCGGTCGTCGGCGTCCAGCCGTTTGGCGGCGAAGGCCTGTCCGGCACCGGGCCAAAA
+GCGGGAGGGCCGCTCTATCTCTACCGCCTGCTGGCACACCGCCCGCCCAATGCGCTCAAT
+ACGACGCTGACTCGTCAGGATGCGCGTTACCCGGTGGATGCGCAGCTTAAAACCACGCTA
+CTCGCGCCGTTGACCGCTCTGACGCAATGGGCGGCGGATCGCCCGGCGCTACAGACGCTC
+TGCCGACAATTCGCCGATCTGGCGCAGGCCGGCACGCAGCGCCTGCTACCGGGGCCGACC
+GGCGAGCGTAATACCTGGACGCTGTTGCCGCGTGAACGGGTGTTATGCCTGGCTGATGAT
+GAACAGGACGCGTTGACGCAGCTTGCCGCCGTTCTCGCCGTCGGCAGTCAGGCGCTATGG
+TCAGACGACGCCTTCCACCGCGATCTGGCGAAACGTCTCCCCGCCGCCGTCGCGGCGCGT
+GTCCAGTTTGCGAAAGCGGAAACGCTGATGGCGCAGCCGTTTGACGCGGTGATTTTCCAC
+GGCGACTCCGACAAGCTGCGAACCGTGTGCGAAGCCGTCGCCGCCCGCGAAGGCGCGATA
+GTGTCGGTACAGGGGTTCGCCCGCGGCGAAAGCAATATGCTGCTGGAACGGCTCTATATT
+GAACGTTCGCTGAGCGTAAACACTGCCGCCGCTGGCGGTAATGCCAGCCTGATGACAATT
+GGCTAAATGGCTATTAGCACACCGATGTTGGTGACATTCTGTGTCTATATTTTTGGCATG
+ATATTGATTGGGTTTATCGCCTGGCGCTCAACCAAAAACTTTGATGACTATATTCTTGGC
+GGTCGCAGCCTGGGGCCGTTTGTTACGGCTTTATCAGCCGGCGCGTCGGATATGAGCGGC
+TGGCTGTTAATGGGGCTGCCTGGCGCTATCTTTCTGTCGGGGATCTCTGAAAGCTGGATC
+GCCATTGGCCTGACGTTAGGCGCATGGATTAACTGGAAGCTGGTGGCCGGGCGCCTGCGC
+GTGCATACCGAATTTAACAATAACGCGCTCACGCTGCCGGACTATTTTACCGGTCGGTTT
+GAGGATAAGAGCCGAGTCCTGCGTATTATTTCCGCGCTGGTCATTCTGCTGTTTTTCACT
+ATCTATTGCGCATCAGGTATTGTCGCTGGGGCACGACTGTTCGAAAGCACCTTCGGTATG
+AGCTATGAAACCGCACTGTGGGCGGGGGCCGCGGCAACCATTATTTATACCTTTATCGGC
+GGGTTTCTTGCCGTTAGCTGGACGGATACCGTTCAGGCCAGCCTGATGATTTTTGCGTTA
+ATCCTGACGCCGGTGATGGTTATTGTCGGCGTAGGCGGTTTTAGCGAGTCGCTGGAAGTG
+ATCAAGCAAAAGAGCATCGAGAATGTCGACATGCTCAAGGGGCTGAATTTTGTCGCTATT
+ATTTCTCTGATGGGCTGGGGGCTGGGTTACTTCGGTCAGCCGCATATCCTGGCGCGCTTT
+ATGGCGGCGGATTCCCATCACAGTATTGTTCATGCGCGTCGTATCAGTATGACCTGGATG
+ATTCTGTGTCTGGCGGGCGCGGTGGCGGTGGGCTTCTTTGGCATTGCGTACTTTAACAAT
+AACCCCGCGCTGGCCGGGGCGGTGAACCAAAACTCAGAACGCGTATTTATTGAACTGGCG
+CAGATCCTGTTTAACCCGTGGATTGCCGGTGTTCTGCTGTCTGCTATCCTGGCGGCGGTG
+ATGTCGACGTTGAGCTGTCAGTTGCTGGTATGCTCCAGCGCGATTACGGAAGATTTATAT
+AAGGCTTTTCTGCGTAAAAGCGCCAGCCAGCAAGAGCTGGTATGGGTAGGGCGAGTGATG
+GTGCTGGTGGTAGCGCTGATCGCCATTGCGCTGGCGGCGAATCCTGATAACCGTGTGCTG
+GGGCTGGTGAGCTACGCCTGGGCTGGATTCGGCGCGGCATTTGGACCTGTTGTCCTGTTT
+TCTGTGATGTGGTCGCGTATGACACGTAACGGCGCGCTGGCGGGAATGATTATTGGCGCG
+GTGACGGTTATCGTCTGGAAACAATATGGCTGGCTGGATCTGTATGAGATTATCCCTGGC
+TTCATTTTCGGCAGCCTGGGGATCGTAATCTTTAGCCTGCTTGGCAAAGCGCCGACAGCA
+ACGATGCAGGAACGCTTTGCAAAAGCGGACGCGCATTATCATTCCGCGCCGCCGTCGAAG
+CTACAGGCGGAATAAATGGCGGGTAAACTGCGGCGTTGGCTGCGTGAAGCCGCGGTTTTT
+CTGGCGCTCCTCATCGCGATAATGGTGGTCATGGACGTCTGGCGCGCGCCGCAGGCGCCT
+CCGGCGTTTGCCGCGACACCATTACATACGCTGACGGGAGAGTCGACAACTCTGGCGACC
+TTGAGCGAGGAACGCCCCGTACTGCTCTATTTTTGGGCCAGCTGGTGCGGGGTATGCCGC
+TTTACCACGCCTGCGGTCGCTCACCTGGCGGCGGAAGGGGAAAACGTCATGACCGTTGCG
+CTCCGCTCCGGCGGTGATGCTGAGGTTGCCCGCTGGCTGGCGCGCAAGGGCGTTGACTTC
+CCGGTCGTCAATGATGCTAACGGCGCCTTATCCGCTGGCTGGGAAATCAGCGTGACGCCA
+ACGCTGGTGGTGGTTTCACAAGGTCGGGTTGTGTTCACCACCAGCGGCTGGACCAGCTAT
+TGGGGCATGAAGCTTCGGCTGTGGTGGGCAAAAACGTTCTGAATGATGAAAAAAAGCGTC
+GCTATGCTGGCGGTTTGTATGCTGGCGCAAAGCCACCTTGCCATTGCTGCCGGTGCTCCT
+GCGCCTCAAGAGATCAACATTGTTTTACTGGGCACCAAAGGCGGGCCTTCTTTGCTCAAT
+ACAGCCAGACTACCGCAAGCGACGGCGCTCACTATCGGCGATAAGATATGGCTGATAGAT
+GCCGGCTACGGCGCCAGTCTGCAACTGGTGAAAAATGGCATTCCACTGCGCAACATCAAT
+ACTATTTTGCTCACCCATCTGCACAGCGACCACATACTGGATTATCCTTCCTTGCTGATG
+AATGCCTGGGCAAGTGGCCTGAAAGACCATACCATACAGGTTTATGGCCCGCCGGGAACC
+CAGGCGATGACGAAGGCTAGCTGGAAGGTCTTTGACAGGGATATCACGTTACGCATGGAA
+GAAGAGGGGAAACCCGATCCGCGCAACCTGGTTAAGGCGACCGATATCGGCCAGGGCGTC
+ATCTATAAAGATGAACTGGTCACAATAAGCGCGCTGAAAGTGCCTCATTCCCCTTTCCCG
+GACGGTGAAGCGTTTGCTTACCGTTTTGATACTCAGGGTAAGCGAATCGTCTTCTCTGGC
+GATACGTCCTGGTTTCCTCCGCTTGCAACGTTTGCCCAGGGGGCGGATATCCTGGTACAT
+GAGGCGGTACATGTCCCTTCGGTAGCAAAACTGGCTAATAGTATTGGCAACGGAAAAACG
+CTGGCTGAAGCGATTGCGTCGCATCACACCACGATTGAAGATGTCGGTAAGATTGCTCGC
+GAGGCCCACGTGAAAAAACTGGTGTTAAGTCATCTGGTGCCTGCGACGGTTGCGGATGAC
+GTCTGGCAACAGGAAGCCATGAAAAATTACCCGGGCCCTGTCATTGTCGGTCATGACAAT
+ATGACGATAAGCGTACCGTAAATGTCGCAACGCACAGAGAAAAAAATCGGGAAACGTTCG
+CAGGCCACCGGTGCAAAACGGCAGCTTATCTTAACCGCCGCGCTTGCCGTTTTTTCCCAG
+TATGGCATTCATGGCGCGCGTCTTGAACAGGTCGCCGAGCGGGCAGGCGTCTCCAAAACC
+AATCTGCTTTATTATTATCCCTCGAAAGAGGCGCTGTATGTCGCGGTAATGCGACAGATT
+CTGGATGTCTGGTTGGCGCCGCTCAAGGCGTTTCGCGCAGAATTTTCCCCTCTGGAGGCC
+ATCAAAGAGTATATCCGTCTCAAGCTGGAGGTTTCGCGTGATTATCCGCAGGCGTCGCGG
+CTCTTCTGCATGGAGATGCTGGCGGGCGCGCCGCTCTTAATGGATGAACTGACCGGCGAT
+CTAAAAGCGTTGATAGATGAAAAATCCGCGCTGATTGCCGGATGGGTGCACAGCGGGAAA
+CTCGCGCCCGTTTCTCCGCATCATTTGATCTTCATGATTTGGGCCGCCACGCAACATTAC
+GCCGATTTCGCCCCTCAGGTTGAAGCGGTAACCGGCGCGACGCTTCGCGATGAAGCCTTT
+TTCAACCAAACGGTCGAAAGCGTTCAGCGCATTATTATTGAAGGGATTCGCGTGCGTTAA
+ATGGCGAAACAACAACGGATGGGCTGGTGGTTTCTTTGCCTTGCATGTGTCGTGGTAATG
+GTTTGTACCGCGCAACGCATGGCGGGCCTGCACGCCTTGCAGATGCAGGCGACGGCCTCT
+GCTGCGGTGGTCAGCGCTCCCTCCTCGACAGATGACGGCTCGCCGGTCACTCCCTGCGAA
+TTAAGCGCCAAGTCGCTGCTGGCGGCGCCTCCAGTACTCTTTGAAGGTGCTATCCTTGCG
+CTTTATCTACTGCTTTCCTTACTGGCGCCTGTCCGGGTCATGCGCCTGCCGTTTTCGCCT
+CCACGGGCTATTTCGCCGCCCACATTACGGGTACATCTACGATTTTGTGTCTTCCGTGAA
+TGAATGATGATTTTATTCAGGCGGATACTGTTCTGCCTGTTATGGCTTTGGCTGCCCGTC
+TCCTGGGCGGCGGAAAGCGGCTGGCTGCGTTCGCCCGATAACGACCATGCCAGCATACGG
+CTACGTGCCGATACGTCCGCTAACAGTGAGACCCGGCTGTTGCTGGATGTCAAACTGGAA
+AACGGCTGGAAAACCTACTGGCGCGCGCCGGGGGAAGGGGGCGTGGCACCCTCTATCGCC
+TGGAAAGGCGACATGCCTGAGGTAAGCTGGTTCTGGCCAACCCCCTCGCGCTTTGATGTG
+GCGAATATCACCACCCAGGGATATCACGACGAGGTGACCTTTCCGATGATCGTGCGCGGT
+ACGCCGCCGGCGACCTTGCGCGGTGTGTTGACGTTATCAACCTGCAGCAATGTTTGTCTG
+TTGACCGATTACCCCTTTTCCGTGACGCCCACTGTGCAGAATGCCGATTTTGCCCATGAC
+TATGCGCGGGCGATGGGTAAAGTTCCGCTCCGCAGTGGGCTAACGGACTCGCTTGACGTT
+GGCTATCGCCCGGGAGAACTGGTGGTCACTGCTACGCGAGCGGCGGGCTGGTCATCGCCC
+GGGCTCTATCTTGACACCATAGATGACGTCGATTTTGCGAAGCCTCGCCTGCGCGTAGAG
+GGCGACAGGTTACAGGCGACGGTGCCGGTGACGGACAGTTGGGGCGAAAAGGCGCCCGAT
+TTGCGCGACAAATCGCTGACCCTCGTGTTAGCCGATGGCGCTATCGCCCAGGAGAGCACG
+CAAACCATTGGCGCTGCGCCAGCGCAAACGCCGGACAATGCGGCGCTACCTTTCTGGCAA
+GTTGTAATGATGGCGCTAATCGGCGGACTGATTCTTAATTTAATGCCCTGCGTACTGCCT
+GTTCTGGGCATGAAACTTGGCTCTATTTTATTGGTAGAGGAAAAAAGCCGCTCTCACATC
+AGGCGACAATTTTTGGCTTCGGTCGCCGGTATCATTGCGTCATTTATGGCGCTGGCGGCG
+TTTATGACCCTCCTTCGCCTGTCAAACCATGCGCTGGCCTGGGGAGTCCAGTTCCAGAAT
+GCATGGTTTATTGGTTTTATGGCGCTGGTGATGTTGTTGTTTAGCGCCAGCCTGTTCGGG
+CTTTTTGAGTTCAGGCTTCCCTCATCTATGACCACGAAACTGGCCACTTACGGCGGTAAC
+GGTATGTCGGGACATTTCTGGCAGGGGGCGTTCGCCACGCTGCTGGCGACGCCTTGTAGC
+GCGCCGTTTCTGGGCACGGCGGTCGCGGTGGCGCTCACGGCGTCGCTGCCGACGCTGTGG
+GGGCTGTTCCTTGCGCTTGGCCTGGGAATGAGCGCGCCGTGGCTACTGGTCGCGATACGA
+CCAGGGCTTGCGCTACGTTTACCGCGCCCCGGGCGTTGGATGAATGTCCTGCGCAGGATC
+CTCGGTCTGATGATGCTGGGGTCGGCTATCTGGCTGGCGACGTTACTCCTGCCGCATTTC
+GGCTTCACTGCGTCAAAGAGCGCGCAAGACACGGTTCAGTGGCAACCGTTGAGTGAACAG
+GCAATCCAGTCGGCGCTGGCGCAGCATAAGCGGGTATTTGTCGATGTCACTGCGGACTGG
+TGTATTACCTGTAAAGTGAATAAATACAACGTCCTGCAAAAAGAGGATGTGCAGGCCGCC
+TTGCAACAGCCGGATGTTGTGGCGCTGCGGGGAGACTGGACGCTGCCGTCCGATGCCATT
+ACAGATTTTCTGAAAACGCGCGGCCAGGTCGCCGTGCCGTTTAATCAGGTATATGGCCCC
+GGTTTGCCGGAAGGGGAGGCACTGCCCACTTTGCTGACCCGCGATGCGGTATTACAAACG
+TTGAAAAAAGCGAAAGGAATAACCCAATGAATGAAATACATGATTGTTTTACTGCTGGCG
+CTGTTTTCGACGCTGAGCATCGCGCAAGAAACCGCTCCTTTTACGCCGGATCAGGAAAAG
+CAGATTAAAAATCTGATCCATGCGGCGTTGTTTAACGATCCTGCCAGCCCGCGGATAGGC
+GCTAAACACCCTAAGCTGACGCTGGTGAACTTTACGGATTACAACTGCCCGTACTGCAAA
+CAGCTCGATCCGATGCTGGAAAAGATTGTGCAGAAATATCCTGACGTTGCGGTCATTATT
+AAACCGCTGCCATTCAAAGGAGAGAGTTCCATACTGGCGGCGCGTATTGCGCTGACCACC
+TGGCGCGATCATCCGCAACAGTTCCTCGCGCTACATGAAAAACTTATGCAAAAGCGCGGT
+TACCATACGGATGACAGTATTAAACAGGCCCAGCAGAAAGCAGGGGCGACGCCAGTGACG
+CTGGATGAAAAAAGCATGGAAACGATACGCACTAATTTGCAGTTGGCAAGACTGGTCGAC
+GTGCAAGGAACGCCAGCGACGATCATTGGCGACGAGCTGATTCCGGGCGCAGTGCCCTGG
+GATACGCTGGAAGCGGTGGTGAAAGAAAAACTGGCGGCTGCCAATGGCGGGTAAatgatt
+gcacattctttcggcatcgttaattattttgtattatttggctacctcctggccatgatg
+gtagtcggtgtctatttttccagacggcaaaaaacagcagacgattattttcgcggtggt
+ggccgggttcctggttgggcggctggggtcagtgtatttgctactacgttaagctcaatt
+gcatttatgtcaattcctgccaaagcgtttacttccgactggacgtttatcattggtcag
+gatctggctatcgcaattttaccgctggttttttatttctatattccgttttttcggaaa
+gtgaaagtcacatcagcctatgaatatctcgaagcacggttcgatgtgcgctgccgtctg
+gtcgccagcatgtcatttatgttgtttcatattggacgtatcgccattatcactttcctc
+gccgtgctggccttgcgccccttcatcgctatagacccggtgattttggtactgttgatt
+ggtgtgatgtgtatcatttatacctggatgggggggaattgaatggaaagtctattaaat
+cgtttatatgacgcgttaggcctggatgcgccagaagttgagccactgcttatcattgat
+gatgggatacaggtttattttaatgaatccgatcatatactggaaatgtgctgtcccttt
+atgccactgcctgacgacactctgactttgcagcattttttacgtcttaactacgccagc
+gccgtcactatcggcgctgatgcagacaatactgctttagtggcgctttatcgcttgccg
+caaaccagtaccgaagaagaggcgctcactggttttgtattattcatttcaaacgtgaag
+caattgaaagagcattatgcataaATGAAATACGACCTTATTATTATCGGCAGCGGTTCG
+GTTGGCGCCGCCGCTGGTTATTACGCCACCCGCGCCGGGCTAAAGGTCCTGATGACCGAT
+GCGCATATGCCGCCTTATCAACAGGGCAGCCACCACGGCGATACCCGTCTTATCCGCCAC
+GCTTATGGTGAAGGCGAAAAATATGTCCCGCTGGTGCTTCGCGCCCAGACGCTTTGGGAT
+GAGCTCTCCACACACAATGAAGAGCCTATTTTTGTCCGCTCCGGCGTCGTCAACCTCGGC
+CCGGCCGATTCCGCTTTCTTAGCCAACGTCGCACGAAGCGCGCAACAGTGGCAATTGAAC
+GTCGAGCGCCTGGACGCGACGGCCCTCATGACGCGCTGGCCGGAAATTCGCGTGCCCGAT
+AATTATATCGGGCTGTTTGAAGCTGACTCCGGTTTCCTGCGCAGCGAATTAGCCATTACC
+ACATGGCTTCGTCTGGCCCGAGAGGCAGGCTGCGCACAGCTATTCAACAGCCCGGTAAGC
+CATATTCACCATGATGATAACGGTGTGACGATAGAGACGAGTGAAGGCTGCTACCACGCC
+AGCAAAGCGCTGATTAGCGCGGGCACCTGGGTCAAAACGCTGGTACCGGAGCTGCCCGTT
+CAGCCCGTACGTAAAGTTTTTGCCTGGTTTAAGGCGGATGGACGTTACAGCACTAAAAAC
+CGCTTTCCGGCCTTTACCGGCGAAATGCCCAACGGCGATCACTATTACGGTTTCCCGGCG
+GAGAACGACGAGTTAAAAATCGGCAAACACAATGGCGGGCAGCGAATACAGGCACCGGAA
+GAGCGCAAGCCCTTTGCCGCCGTTGCCAGCGATGGCGCGGAAGCATTTCCTTTCCTGCGT
+AACGTACTGCCGGGTATCGGCGGTTGTTTACATGGGGCGGCATGTACCTATGATAATTCG
+CCGGACGAGGATTTTATTATCGATACGCTGCCTGGCCATGAGAATACGCTTGTCATCACT
+GGACTCAGCGGACATGGTTTTAAATTCGCCCCGGTGTTAGGAGAAATCGCTGCGGATTTT
+GCGTTGGGAAAAACGCCCTCCTTTGATCTGACGCCGTTCCGGCTTTCCCGTTTTAGCCAA
+TAAatgcaaatacagagcttctatcactcagcttcactaaaaacccaggaggcttttaaa
+agcctacaaaaaaccttatacaacggaatgcagattctctcaggccagggcaaagcgccg
+gctaaagcgcccgacgctcgcccggaaattattgtcctgcgagaacctggcgcgacatgg
+gggaattatctacagcatcagaagacgtctaaccactcgctgcataacctctataactta
+cagcgcgatcttcttaccgtcgcggcaaccgttctgggtaaacaagacccggttctaacg
+tcaatggcaaaccaaatggagttagccaaagttaaagcggaccggccagcaacaaaacaa
+gaagaagctgcggcaaaagcattgaagaaaaatcttatcgaacttattgcagcacgcact
+cagcagcaaaatggcttacctgcaaaagaagctcatcgctttgcggcagtagcgtttaga
+gatgctcaggtcaagcagctcaataaccagccctggcaaaccataaaaaatacactcacg
+cataacgggcatcactataccaacacgcagctccctgccgcagagatgaaaatcggcgca
+aaagatatctttcccagtgcttatgagggaaagggcgtatgcagttgggataccaagaat
+attcatcacgccaataatttgtggatgtccacggtgagtgtgcatgaggacggtaaagat
+aaaacgcttttttgcgggatacgtcatggtgtgctttccccctatcatgaaaaagatccg
+cttctgcgtcaggccggcgctgaaaacaaagccaaagaagtattagctgcggcacttttt
+agtaaacctgagttgcttaacagagccttagagggcgaagcggtaagcctgaaactggta
+tccgtcgggttactcaccgcgtcgaatattttcggcaaagagggaactatggtcgaggat
+caaatgcgcgcatggcaatcgttgacccagccgggaaaaatgattcatttaaaaatccgc
+aataaagatggcgatctacagacggtaaaaataaaaccggacgtcgccgcatttaatgtg
+ggtgttaatgagctggcgctcaagctcggctttggccttaaagcatcagatagctataat
+gccgaagcgctacatcagttattaggcaatgatttacgccctgaagccagaccaggtggc
+tgggttggcgaatggctggcgcaatacccggataattatgaggtcgtcaatacattagcg
+cgccagattaaggatatctggaaaaataaccaacatcataaagatggcggcgaaccctat
+aaactcgcacaacgccttgccatgttagcccatgaaattgacgcggtgcccgcctggaat
+tgtaaaagcggcaaagatcgtacagggatgatggattcagaaatcaagcgagagctcatt
+tctttccatcagacccatatgttaagtgcgcctggtagtcttccggatagcggtggacag
+aaaattttccaaaaagtattactgaatagcggtaacctggagattcagaaacaaaatacg
+ggcggggcgggaaacaaagtaatgaaaaatttatcgccagaggtgctcaatctttcctat
+caaaaacgagttggggatgataatatttggcagtcagtaaaaggtatttcttcattaatc
+acatcttgaATGAAACGATATATACTGGCTACCGCGATAGCGTCTCTTGTTGCAGCCCCG
+GCAATGGCGCTGGCCGCTGGCAGCAATATTCTCAGCGTACATATTCTCGATCAGCAAACA
+GGCAAACCAGCGCCCGGCGTGGAGGTGGTACTGGAGCAGAAAAAGGATAACGGATGGACG
+CAATTAAACACCGGGCATACCGACCAGGATGGACGAATTAAAGCACTGTGGCCCGAAAAA
+GCTGCCGCGCCGGGGGATTATCGCGTTATTTTTAAAACCGGCCAGTATTTTGAAAGTAAA
+AAACTGGACACGTTTTTCCCGGAGATTCCCGTCGAGTTTCATATCAGCAAAACGAATGAG
+CACTATCATGTGCCGCTGTTATTAAGTCAGTATGGTTATTCAACCTATCGCGGGAGCTAA
+ATGGCAAAGATTCTGGTGCTCTATTATTCCATGTACGGACACATTGAAACCATGGCGCAC
+GCGGTGGCGGAAGGGGCAAAGAAAGTCGACGGCGCAGAGGTCATTATAAAGCGTGTGCCA
+GAAACAATGCCGCCTGAAATCTTCGCAAAAGCTGGCGGTAAAACGCAAAACGCACCGGTT
+GCCACCCCACAGGAGCTGGCGGATTACGATGCCATTATTTTTGGTACGCCAACCCGGTTT
+GGCAATATGTCAGGCCAGATGCGTACCTTCCTGGACCAAACCGGCGGACTGTGGGCATCC
+GGCGCGCTATACGGCAAGCTCGGCGGCGTGTTCAGTTCTACCGGAACGGGCGGCGGCCAG
+GAGCAGACCATCACCTCGACCTGGACTACGCTTGCCCATCATGGGATGGTGATTGTCCCG
+ATAGGCTATTCCGCACAGGAACTGTTTGACGTCTCCCAGGTTCGCGGCGGTACGCCTTAC
+GGCGCAACGACTATCGCTGGAGGCGACGGTTCACGTCAACCAAGCCAGGAGGAACTCTCT
+ATCGCTCGCTATCAGGGGGAATACGTCGCCGGTCTGGCAGTCAAACTCAACGGCTAAatg
+gagcctcaacccccacgtctgaaacccggaaaaatccttgacactctgggtgctatgcaa
+aaaagcctgacacgtgcctcgcagcgtattgcgcaatatattttagccttccccagacag
+gtgacacagtcatctattgcggatttgtcgcgcgacacacaggccggagaagccacggtt
+attcgcttttgtcgcaccctgggctataaaggttttcaggattttaaaatggacctggcc
+attgaacttgccactaccgagtctgatgacagtagtcctctactggatgccgaagttagc
+gaatccgacgatgcccacgcgattggtttaaaattgcagaacaccattagtaatgtatta
+tctgaaacgctaaatctgctggatatgcaacaggttctcggtgtcgtggacgccctacgt
+cactgtcactcagtttatatgtttggtgtgggctcatcggggatcacggcgctggatatg
+aaacacaagctaatgcgtatgggtttacggggcgatgcggtaagcaataaccattttatg
+tacatgcaggctacgctattgaaagcaggcgatgtcgcgatgggtgtcagtcactcgggc
+acatcgccagaaacagtgcattcactccgattggcccgacaggctggcgccaccacagtc
+gccattacccataatctgggttctccattatgtgaagaggccgatttttgcctgatcaat
+ggtaatcggcaaggaatgttgcagggtgactcgatcggtacgaaagccgcgcagcttttc
+gtctttgacctgctctatacccttcttgtacagtcctcgccggaacaggcccgagaaagc
+aaattacggacaatgaatgccctggacatgacaaaataaATGAAGAAACTGCCCGGCTTT
+ACGCAAGATTACTTACTCAGCAAGGCGACGACCCTGCCTGATAAAACACGCCTGGAGCGT
+GCCGTTGAACCGCTATGCGCGCGCCATCCCGGAGAGTGCGGCATTCTTGCGCTGGATAAC
+AGTCTGGACGCTTTTGCCGCCCGCTACCGCCTGACCGAAATGGCGGCGCGGACGCTGGAT
+GTGCAGTATTATATTTGGGAAGACGATATGTCCGGGCGGCTGCTCTTTTCGGTTCTGCTG
+TCGGCGGCGAAGCGCGGCGTTCATGTTCGTCTGCTGCTGGATGATAACAATACGCCTGGT
+CTGGATGATACGTTGCGCTTGCTGGATAGCCATCCTAATATCGAAGTTCGTCTGTTTAAT
+CCTTTCTCTTTTCGTACGCTACGCGCGCTGGGATATTTGACGGATTTTGCGCGGCTGAAT
+CGGCGGATGCACAATAAAAGTTACACTGCCGACGGCGTAGTGACGCTGGTCGGTGGGCGC
+AACATCGGCGATGCCTATTTCGGCGCTGGCGAGGAGCCGCTATTTTCCGATCTGGACGTG
+ATGGCCATTGGCCCGGTGGTCAATGATGTCGCCAATGATTTTGAACGTTACTGGCGCTGT
+AGTTCAGTGTCGACATTGCAGCAAGTATTATCCCTTTCTGAGCAGGAACTGACGCAGCGT
+ATCGAACTTCCCGAATCCTGGTATAACGATGAGATCACCCGCCGTTATCTGCATAAGCTG
+GAAACCAGCCAGTTTATGGCGGATCTCGATCGCGGAACGTTGCCGCTGATTTGGGCAAAA
+ACACGCTTGCTTAGCGATGACCCTTCTAAAGGCGAGGGGAAGGCGCAGCGCCATTCGCTT
+CTTCCGCAGCGATTATTTGACGTGATGGGGTCGCCGACGGAGCGTATCGACATTATTTCC
+GCTTACTTTGTCCCTACGCGCGCAGGCGTGGCGCAGTTGCTTAATCTGGTCAGGAAAGGT
+GTGAAGATCGCCATCTTAACTAACTCTCTGGCGGCCAACGATGTGGCGGTCGTTCACGCA
+GGGTACGCGCGCTGGCGCAAGAAATTACTGCGCTATGGCGTGGAGCTCTACGAACTGAAA
+CCGACCCGCGAACATGAAACCGCCGTACATGATCGCGGACTCACCGGGAACTCAGGTTCC
+AGCTTACATGCTAAAACGTTCAGTATTGATGGTAGTAAGGTGTTTATCGGGTCGCTTAAT
+TTTGATCCCCGTTCAACGCTTTTAAATACCGAAATGGGCTTTGTCATTGAAAGTGAAACG
+CTGGCGACGCTTATTCATAAGCGTTTTACGCAGAGCCAACGCGATGCGGCCTGGCAACTG
+CGGCTGGATCGCTGGGGACGAATTAACTGGATCGATCGTCAGCAAGAAGAGGAAAAGGTG
+TTAAAGAAAGAACCCGCTACGCGTTTCTGGCAGCGAGTTCTGGTACGGTTGGCGGCAATT
+TTACCTGTGGAATGGTTGCTGTGAATGCCAACTCAAGAAGCAAAAGCGCACCGCGTCGGC
+GAATGGGCAAGCCTGCGTAATACGTCGCCGGAAATTGCCGAAGCCATTTTTGAAGTCGCT
+CACTATGACGAGAAACTGGCAGAAAAAATATGGGAAGAAGGTAGCGATGAGGTGCTGATC
+AAAGCCTTTGAGAAAACGGACAAAGACTCGCTCTTCTGGGGCGAACAAGTCATCGAACGT
+AAGAACGTATAAatgtatcccgttgacctgcatatgcataccgtcgcgagcactcatgcc
+tacagtactctgagcgattatatcgcggaagccaaacgcaaaggcatgaaactttttgcg
+attaccgatcatggtccggacatggaagatgcgccgcatcactggcagtttattaacatg
+cgcatctggccgcgtctggttgacggcgtggggatactgcgtggcatggaggcgaatatc
+aagaatattaacggtgaaattgattgttccggaaagatgttcgactcgctggatctgatt
+atcgcaggctttcatgagcccgtttttgcgccgcatgataaagaaacgaatactcaggcg
+atgatcgcgaccatcgccagcggcaaggtgcatataattagtcacccgggaaatccaaag
+tatccagtggaggttaaagccatcgcgcaggcggcggcgaaacaccaggtagcgctggaa
+atcaacaactcttcttttctgcattcgcgtaaaggaagcgaagataagtgccgcgcggtc
+gctgccgccgtacgcgatgcgggaggctgggtagcgttaggctctgagtcccatacggcc
+tttacgcttggcgatttcaccgaatgccggaaaattctggatgcggtgaattttccggaa
+gatcgaatcctgaacgtctctccgcagcgcttactggcctttctcgagtcacgcggtatg
+gcgcctgtaccggaatttgccgaactttaaatgaatgagttttcaatcctgtgccgtgtg
+ctgggatcgttgttttaccgccaagcgcaagatcctttactggttccgctgtttacgtta
+atccgtgaaggtaaactggcggcagactggccgctggagcaggatgacatgctggcgcgt
+ttacagaaaagctgcgatatcacggagatttccactgattacaatgcgttatttgttggg
+gaagagtgcgcggtagcgccatacggcagtgcgtgggtcgaaggcgcggaagagtctgag
+gtgcgcgcttttttaacgtcgcgagggatgccgctggccgatacgcctgccgatcacatt
+ggcactttattgctcgcggcctccgggctggaagatcagtctgccgaagatgaaagtgaa
+gcgctggaaaccttatttgccgatgatctgcttccctggtgcaataccttcctcggtaaa
+gttgaagcccatgccgttacgccagtctggcgcactctggcgccgctaacgcgtgatgcg
+ataggggccatgtgggatgaacttgaggaagaagatgaagaataaatgatgcgcgcgatg
+aacatacttctttctattgctatcactacgggcatcctttctggaatatggggatgggtg
+gccgtctccctggggttactaagctgggccggttttttaggctgtacggcttatttggcc
+tgtccgcagggcggctttaagggattgttgatttccgcctgtacgctgttaagcgggatg
+gtgtgggcgctggtcattattcacggtagcgcgttggcgccgcatctggaaattgtgagt
+tacgtgttgacggggatcgtggcattcctgatgtgtatccaggcaaagcagctattgctt
+tcttttgttccgggaacatttatcggcgcctgcgcgacatttgcagggcagggtgagtgg
+cggttggtattaccgtcgctggcgctggggctaatctttggctatgccatgaaaaagagt
+gggctatggctggcatcacgccgcgagcaacattcagcgaatacggcggtcacaaagtaa
+ATGAAAAAAAACCTGCTGGGATTCACCCTCGCATCCTTGTTATTCACGACCGGTTCCGCC
+GTGGCGGCGGAGTATAAAATTGATAAAGAAGGCCAACATGCGTTCGTCAATTTCCGCATC
+CAGCATCTGGGCTACAGCTGGCTATACGGCACCTTTAAAGATTTCGACGGCACGTTCACT
+TTTGACGAAAAAAATCCGTCAGCAGACAAAGTGAATGTGACCATTAACACCAATAGCGTC
+GACACTAACCATGCCGAACGTGACAAACACCTGCGTAGCGCGGAGTTTCTTAATGTTGCG
+AAATTCCCGCAGGCAACCTTCACCTCTACCAGCGTGAAAAAAGAGGGCGATGAACTGGAT
+ATTACCGGCAATCTGACGCTCAATGGCGTGACTAAACCGGTGACGCTGGAAGCGAAGCTG
+ATGGGCCAGGGCGACGATCCGTGGGGCGGTAAGCGCGCGGGCTTTGAGGCCGAAGGAAAA
+ATTAAGCTGAAAGATTTCAATATAACTACCGATCTCGGCCCAGCCTCACAAGAGGTGGAG
+CTTATCATCTCAGTAGAAGGCGTTCAGCAGAAGTAAATGTTACTGATGATGGCGCTGATC
+GTGCGTATTATCTGGCGGCTTTATTCTCCGCCGCCCGTTGCGTTGACCAGCTATTCCCGT
+TTAACGCGCATTGGCGCCGCCGCGGGTCATATCCTTCTGTATCTCCTGCTCTTTGCGATA
+ATCATTAGCGGCTACCTGATTTCCACCGCCGACGGTAAACCGATTAGCGTCTTTGGCTGG
+TTTGAGATTCCGGCCACGCTTACGGACGCGGGCGCGCAGGCTGACATCGCCGGAACACTG
+CATCTGTGGTTTGCCTGGTCGCTGGTCATTATCTCGCTCTCGCATGGGGTTATGGCGCTA
+AAACACCATTTCATCGATAAAGACGACACACTGAAACGTATGACAGGAATGTCGTCATCT
+GACTATGGAGCTCAAAAATGAATGGTTAAGTTATCAATGACGCTGCGCCTGACAATTTCT
+TTTATCGCCATACTTATCCTCGCCTGTACCGGCATTAGCTGGACGCTCTATAACGCGCTG
+AGCAAAGAATTAACGTATCGGGATGATATGACGCTAATAAATCGGGCGGCGCAAATGCAG
+CAACTGTTACTGGATGGCGCCAGGCCGGAAAATCTGCCGCTCTATTTCAATCGGATGGTG
+GATACGAAGCAGGATATCTTATTGATCCACTCAGCAACAGGCCATAATGTTGCGATTAAT
+CATAGCGGCATCCCCGACCAACGCTTTAACGAGATTCCGCTGGCTAAAAACATCACCCGC
+GAAACCTTATTTCGCCAGGCGGTACAAGGCACGGAGCTGACCGCGGTACGAGTAAACGCC
+AGAAGCGGCGATAACCCGCTGACCCTTACTATTGCCAGGCTGGCGACGGAAAGGCGGCAA
+ATGCTGGCGCAATATCGCCGCAACAGTTTGCTGATTAGCCTTATCGCGATCCTCGTCTGT
+TCGGCGCTCAGTCCATTAGTCATCAGAAACGGGCTGCGGGCCATTACGTCGCTCAGCCGA
+CTCACCGCGGCGACAGATAGCGGCACACTTCGCCAGCCGCTGGCGGAACAGGCGTTACCC
+GTCGAGCTCAGGCCGCTTGGGCAAGCGCTAAATACCATGCGCCAGAAGCTTTCCGACGAT
+TTTGAACGCCTGAACCAATTTGCCGACGATCTGGCGCATGAGCTGCGCACGCCGGTTAAT
+ATTTTACTGGGGAAGAATCAGGTTATGCTGAGTCAGGAACGCAGCGCCGAAGAGTATCAA
+CAAGCCCTTGTCGATAATATTGAAGAGCTGGAGGGACTGTCGCGACTGACAGAAAATATT
+CTCTTTCTGGCACGCGCGGAGCACCAGAATATAGCGGTAAAAAAACAGCCTGTTTCGCTC
+AATGCGCTGGTCGAAAATATGCTGGATTATCTTAGCCCCCTTGCCGAAGAGAAGCACATC
+TGTTTTATAAATCAATGTCAGGGAACGGTATGGGCTGACGAAATATTATTACAAAGAGTG
+CTCTCAAACCTGCTGACGAATGCCATCCGTTATTCTGATGAAAACGCCGTGATACGTATT
+GAAAGCGCTTATGATGATAACGTTGCAGAAATTCGGGTCGCTAATCCGGGCAGCCCCACC
+GCCGATGCGGATAAGCTTTTCCGGCGTTTTTGGCGAGGAGATAATGCCCGCTACACTGCC
+GGTTTCGGCCTGGGGTTATCGTTAGTTAACGCGATTGCCCTATTGCACGGTGGCTCGGCA
+TCTTACCGCTATGCCGATGAACATAATATCTTTTCGGTTCGTCTGCCTGATAGCGGTGAT
+AGCTAAgtgatatgtctgaaagtccagggcggcattggtgaaatttttacggtgacgcag
+caggcggataaattcttgccggctacgcagttccactggagctggacggaaagcacagta
+cctgtattgatgattgggtttctgtttgccaatattcagcaatttactgccagtcaggat
+gtggtccaacgctatatggtgactgactccatagaggaaacgaagaaaacattacttaca
+aatgccaaactggttgcggtgatccctgttttcttttttgctatcggctcggcattattt
+gtctactatcagcaacagccacaattattaccggcgggattcaacactggcggcattttg
+cccttattcgtggtcacggaaatgccagtcggcattgcagggttgataatctccgctatt
+ttcgctgccgcgcagtcgagcatctccagcagcttaaacagcatttccagttgttttaat
+tccgatatctatcagcggttgagtcataaaaaaggaacgccagaaaaccgtatgaaaata
+gctaagttagttattctggtcgcgggcctgataagtagcgcggcctcggtatggctggtc
+atggccgatgaatcagagatctgggatgcatttaatagtctgataggtctgatgggaggg
+ccaatgaccggtctgttgatgctgggcattttctttaaacgagcaaatgccgggagtgcg
+gttttaggaattattatgagcgtcattaccgtgctgggcacacgctatgccactgacctt
+aacttcttcttttatggggtcattggctcgctaagcgtggtgatcagcggcgttattttc
+gccccgttatttgccccggcaccgccattgacgctggatgaaaaacctgaaccaaaggtg
+acattatgaATGAAAATCAACAGATATCTTCTGGGTATGGTTTCGTTTATAGCATTTTCA
+TCATATCTACAAGCGGCAACCCTTGATTATCGGCATGAATATGCTGATAGAACCAGAATT
+AATAAAGACCGTATTGCTATAATTGAAAAGCTTCCTAACGGCATTGGTTTTTATGTCGAT
+GCCAGCGTTAAATCGGGAGGAGTAGATGGTGAGCAGGATAAGCATTTAAGCGATCTCGTC
+GCAAACGCTATAGAACTGGGCGTAAGTTATAATTATAAAGTTACGGACCATTTTGTTTTG
+CAGCCTGGATTTATATTTGAAAGCGGTCCAGACACTTCAATTTATAAGCCTTATTTAAGG
+GCGCAATATAATTTTGATTCTGGTGTTTATATGGCTGGTCGTTACCGTTATGACTATGCA
+AGGAAGACAGCTAACTATAATGATGATGAGAAAACGAATAGATTTGATACTTATATAGGT
+TATGTTTTTGATGAGTTGAAATTGGAATATAAATTTACCTGGATGGATAGCGATCAAATT
+AAATTTGATAACAAAAAAACAAACTATGAACATAATGTGGCTTTAGCCTGGAAACTGAAT
+AAGTCATTTACACCATACGTTGAGGTCGGAAATGTAGCGGTGAGAAATAATACCGATGAG
+AGACAGACCCGTTATCGCGTTGGATTACAATACCACTTTTGAATGACGAAATACGGTGTT
+ATAGGTACAGGTTATTTTGGCGCTGAACTGGCGCGATTTATGTCTAAGGTTGAAGGGGCG
+AAAATCACTGCGATTTACGATCCGGTAAATGCGGCTCCGATAGCGAAAGAGCTGAACTGT
+GTCGCCACTTCAACGATGGAGGCGCTTTGTACCCATCCTGATGTGGATTGCGTAATTATT
+GCTTCACCAAATTACTTACATAAAGCGCCGGTCATTGCGGCGGCTAAAGCGGGTAAACAC
+GTGTTTTGTGAAAAACCTATCGCCTTAAATTACCAGGATTGTAAGGATATGGTTGATGCC
+TGCAAAGAAGCTGGTGTTACCTTTATGGCGGGTCACGTTATGAACTTTTTTCACGGGGTT
+CGCCACGCTAAAGCGCTCATCAAAGCCGGTGAAATCGGTGAAGTTACACAAGTTCACACT
+AAACGTAATGGTTTTGAAGACGTGCAGGATGAGATCTCATGGAAGAAGATTCGCGCAAAG
+TCAGGTGGGCATCTGTACCATCACATTCACGAGCTAGATTGTACACTGTTCATCATGGAT
+GAAACCCCATCCCTGGTTTCAATGGCGGCGGGGAATGTTGCGCACAAAGGTGAAAAATTT
+GGTGATGAAGATGATGTTGTCCTAATCACCCTTGAGTTTGAAAGCGGTCGTTTCGCGACA
+CTTCAGTGGGGATCATCGTTCCACTACCCTGAGCACTATGTATTAATTGAGGGCACGACA
+GGTGCAATTCTCATTGATATGCAAAACACGGCTGGTTATCTAATAAAAGCGGGCAAAAAA
+ACACACTTTCTTGTGCATGAAAGCCAGGCGGAGGATGATGATCGTCGCAACGGTAACATA
+TCCAGCGAGATGGATGGCGCAATCGCTTATGGTAAACCCGGTAAACGTACGCCGATGTGG
+CTCTCATCAATTATGAAACTGGAGATGCAGTACTTGCATGATGTGATAAACGGTCTGGAG
+CCAGGCGAGGAGTTTGCTAAATTGCTAACGGGAGAAGCGGCGACAAATGCCATTGCTACC
+GCTGATGCTGCGACGCTTTCTTCAAACGAGGGGCGCAAAGTTAAACTCACTGAAATTCTT
+GGCTAAATGACATCACGTCTTCAGGTCATACAGGGTGATATCACTCAACTTAGCGTCGAT
+GCGATTGTGAATGCCGCTAACGCATCATTAATGGGCGGCGGTGGCGTAGACGGCGCAATT
+CATCGCGCGGCGGGGCCGGCATTGCTGGACGCCTGTAAACTCATCCGTCAGCAACAGGGC
+GAATGTCAGACGGGACATGCGGTTATCACGCCTGCTGGCAAGCTTTCGGCAAAGGCGGTT
+ATTCACACAGTGGGGCCCGTCTGGCGAGGCGGCGAACACCAGGAAGCTGAGCTACTCGAA
+GAGGCATACCGGAATTGTTTGCTGCTTGCCGAGGCGAATCACTTTCGTTCCATCGCTTTT
+CCGGCAATCAGTACCGGCGTTTATGGCTATCCACGCGCCCAGGCCGCTGAAGTCGCCGTC
+AGGACGGTTTCAGATTTTATTACCCGTTACGCTCTGCCTGAACAGGTATACTTTGTCTGT
+TATGATGAAGAAACTGCCCGGCTTTACGCAAGATTACTTACTCAGCAAGGCGACGACCCT
+GCCTGA
diff --git a/t/data/expected_nnn_at_end.fa b/t/data/expected_nnn_at_end.fa
new file mode 100644
index 0000000..87b65fc
--- /dev/null
+++ b/t/data/expected_nnn_at_end.fa
@@ -0,0 +1,8 @@
+>1
+AAA
+>2
+AAACCC
+>3
+AAACCCGGG
+>4
+AAACCCGGGTTT
diff --git a/t/data/expected_nuc_multifasta.fa.aln b/t/data/expected_nuc_multifasta.fa.aln
new file mode 100644
index 0000000..1548ce8
--- /dev/null
+++ b/t/data/expected_nuc_multifasta.fa.aln
@@ -0,0 +1,90 @@
+>1
+ATGCAAATACAGAGCTTCTATCACTCAGCTTCACTAAAAACCCAGGAGGCTTTTAAAAGC
+CTACAAAAAACCTTATACAACGGAATGCAGATTCTCTCAGGCCAGGGCAAAGCGCCGGCT
+AAAGCGCCCGACGCTCGCCCGGAAATTATTGTCCTGCGAGAACCTGGCGCGACATGGGGG
+AATTATCTACAGCATCAGAAGACGTCTAACCACTCGCTGCATAACCTCTATAACTTACAG
+CGCGATCTTCTTACCGTCGCGGCAACCGTTCTGGGTAAACAAGACCCGGTTCTAACGTCA
+ATGGCAAACCAAATGGAGTTAGCCAAAGTTAAAGCGGACCGGCCAGCAACAAAACAAGAA
+GAAGCTGCGGCAAAAGCATTGAAGAAAAATCTTATCGAACTTATTGCAGCACGCACTCAG
+CAGCAAAATGGCTTACCTGCAAAAGAAGCTCATCGCTTTGCGGCAGTAGCGTTTAGAGAT
+GCTCAGGTCAAGCAGCTCAATAACCAGCCCTGGCAAACCATAAAAAATACACTCACGCAT
+AACGGGCATCACTATACCAACACGCAGCTCCCTGCCGCAGAGATGAAAATCGGCGCAAAA
+GATATCTTTCCCAGTGCTTATGAGGGAAAGGGCGTATGCAGTTGGGATACCAAGAATATT
+CATCACGCCAATAATTTGTGGATGTCCACGGTGAGTGTGCATGAGGACGGTAAAGATAAA
+ACGCTTTTTTGCGGGATACGTCATGGTGTGCTTTCCCCCTATCATGAAAAAGATCCGCTT
+CTGCGTCAGGCCGGCGCTGAAAACAAAGCCAAAGAAGTATTAGCTGCGGCACTTTTTAGT
+AAACCTGAGTTGCTTAACAGAGCCTTAGAGGGCGAAGCGGTAAGCCTGAAACTGGTATCC
+GTCGGGTTACTCACCGCGTCGAATATTTTCGGCAAAGAGGGAACTATGGTCGAGGATCAA
+ATGCGCGCATGGCAATCGTTGACCCAGCCGGGAAAAATGATTCATTTAAAAATCCGCAAT
+AAAGATGGCGATCTACAGACGGTAAAAATAAAACCGGACGTCGCCGCATTTAATGTGGGT
+GTTAATGAGCTGGCGCTCAAGCTCGGCTTTGGCCTTAAAGCATCAGATAGCTATAATGCC
+GAAGCGCTGCATCAGTTATTAGGCAATGATTTACGCCCTGAAGCCAGACCAGGTGGCTGG
+GTTGGCGAATGGCTGGCGCAATACCCGGATAATTATGAGGTCGTCAATACATTAGCGCGC
+CAGATTAAGGATATCTGGAAAAATAACCAACATCATAAAGATGGCGGCGAACCCTATAAA
+CTCGCACAACGCCTTGCCATGTTAGCCCATGAAATTGACGCGGTGCCCGCCTGGAATTGT
+AAAAGCGGCAAAGATCGTACAGGGATGATGGATTCAGAAATCAAGCGAGAGCTCATTTCT
+TTCCATCAGACCCATATGTTAAGTGCGCCTGGTAGTCTTCCGGATAGCGGTGGACAGAAA
+ATTTTCCAAAAAGTATTACTGAATAGCGGTAACCTGGAGATTCAGAAACAAAATACGGGC
+GGGGCGGGAAACAAAGTAATGAAAAATTTATCGCCAGAGGTGCTCAATCTTTCCTATCAA
+AAACGAGTTGGGGATGAAAATATTTGGCGTCAG------NNNAATATTTCTTCATTAATC
+ACATCT
+>2
+ATGCAAATACAGAGCTTCTATCACTCAGCTTCACTAAAAACCCAGGAGGCTTTTAAAAGC
+CTACAAAAAACCTTATACAACGGAATGCAGATTCTCTCAGGCCAGGGCAAAGCGCCGGCT
+AAAGCGCCCGACGCTCGCCCGGAAATTATTGTCCTGCGAGAACCTGGCGCGACATGGGGG
+AATTATCTACAGCATCAGAAGACGTCTAACCACTCGCTGCATAACCTCTATAACTTACAG
+CGCGATCTTCTTACCGTCGCGGCAACCGTTCTGGGTAAACAAGACCCGGTTCTAACGTCA
+ATGGCAAACCAAATGGAGTTAGCCAAAGTTAAAGCGGACCGGCCAGCAACAAAACAAGAA
+GAAGCTGCGGCAAAAGCATTGAAGAAAAATCTTATCGAACTTATTGCAGCACGCACTCAG
+CAGCAAAATGGCTTACCTGCAAAAGAAGCTCATCGCTTTGCGGCAGTAGCGTTTAGAGAT
+GCTCAGGTCAAGCAGCTCAATAACCAGCCCTGGCAAACCATAAAAAATACACTCACGCAT
+AACGGGCATCACTATACCAACACGCAGCTCCCT---GCAGAGATGAAAATCGGCGCAAAA
+GATATCTTTCCCAGTGCTTATGAGGGAAAGGGCGTATGCAGTTGGGATACCAAGAATATT
+CATCACGCCAATAATTTGTGGGTGTCCACGGTGAGTGTGCATGAGGACGGTAAAGATAAA
+ACGCTTTTTTGCGGGATACGTCATGGTGTGCTTTCCCCCTATCATGAAAAAGATCCGCTT
+CTGCGTCAGGCCGGCGCTGAAAACAAAGCCAAAGAAGTATTAGCTGCGGCACTTTTTAGT
+AAACCTGAGTTGCTTAACAGAGCCTTAGAGGGCGAAGCGGTAAGCCTGAAACTGGTATCC
+GTCGGGTTACTCACCGCGTCGAATATTTTCGGCAAAGAGGGAACTATGGTCGAGGATCAA
+ATGCGCGCATGGCAATCGTTGACCCAGCCGGGAAAAATGATTCATTTAAAAATCCGCAAT
+AAAGATGGCGATCTACAGACGGTAAAAATAAAACCGGACGTCGCCGCATTTAATGTGGGT
+GTTAATGAGCTGGCGCTCAAGCTCGGCTTTGGCCTTAAAGCATCAGATAGCTATAATGCC
+GAAGCGCTACATCAGTTATTAGGCAATGATTTACGCCCTGAAGCCAGACCAGGTGGCTGG
+GTTGGCGAATGGCTGGCGCAATACCCGGATAATTATGAGGTCGTCAATACATTAGCGCGC
+CAGATTAAGGATATCTGGAAAAATAACCAACATCATAAAGATGGCGGCGAACCCTATAAA
+CTCGCACAACGCCTTGCCATGTTAGCCCATGAAATTGACGCGGTGCCCGCCTGGAATTGT
+AAAAGCGGCAAAGATCGTACAGGGATGATGGATTCAGAAATCAAGCGAGAGCTCATTTCT
+TTCCATCAGACCCATATGTTAAGTGCGCCTGGTAGTCTTCCGGATAGCGGTGGACAGAAA
+ATTTTCCAAAAAGTATTACTGAATAGCGGTAACCTGGAGATTCAGAAACAAAATACGGGC
+GGGGCGGGAAACAAAGTAATGAAAAATTTATCGCCAGAGGTGCTCAATCTTTCCTATCAA
+AAACGAGTTGGGGATGAAAATATTTGG---CAGTCAGTAAAAGGTATTTCTTCATTAATC
+ACATCT
+>3
+ATGCAAATACAGAGCTTCTATCACTCAGCTTCACTAAAAACCCAGGAGGCTTTTAAAAGC
+CTACAAAAAACCTTATACAACGGAATGCAGATTCTCTCAGGCCAGGGCAAAGCGCCGGCT
+AAAGCGCCCGACGCTCGCCCGGAAATTATTGTCCTGCGAGAACCTGGCGCGACATGGGGG
+AATTATCTACAGCATCAGAAGACGTCTAACCACTCGCTGCATAACCTCTATAACTTACAG
+CGCGATCTTCTTACCGTCGCGGCAACCGTTCTGGGTAAACAAGACCCGGTTCTAACGTCA
+ATGGCAAACCAAATGGAGTTAGCCAAGGTTAAAGCGGACCGGCCAGCAACAAAACAAGAA
+GAAGCTGCGGCAAAAGCATTGAAGAAAAATCTTATCGAACTTATTGCAGCACGCACTCAG
+CAGCAAAATGGCTTACCTGCAAAAGAAGCTCATCGCTTTGCGGCAGTAGCGTTTAGAGAT
+GCTCAGGTCAAGCAGCTCAATAACCAGCCCTGGCAAACCATAAAAAATACACTCACGCAT
+AACGGGCATCACTATACCAACACGCAGCTCCCTGCCGCAGAGATGAAAATCGGCGCAAAA
+GATATCTTTCCCAGTGCTTATGAGGGAAAGGGCGTATGCAGTTGGGATACCAAGAATATT
+CATCACGCCAATAATTTGTGGATGTCCACGGTGAGTGTGCATGAGGACGGTAAAGATAAA
+ACGCTTTTTTGCGGGATACGTCATGGTGTGCTTTCCCCCTATCATGAAAAAGATCCGCTT
+CTGCGTCAGGCCGGCGCTGAAAACAAAGCCAAAGAAGTATTAGCTGCGGCACTTTTTAGT
+AAACCTGAGTTGCTTAACAGAGCCTTAGAGGGCGAAGCGGTAAGCCTGAAACTGGTATCC
+GTCGGGTTACTCACCGCGTCGAATATTTTCGGCAAAGAGGGAACTATGGTCGAGGATCAA
+ATGCGCGCATGGCAATCGTTGACCCAGCCGGGAAAAATGATTCATTTAAAAATCCGCAAT
+AAAGATGGCGATCTACAGACGGTAAAAATAAAACCGGACGTCGCCGCATTTAATGTGGGT
+GTTAATGAGCTGGCGCTCAAGCTCGGCTTTGGCCTTAAAGCATCAGATAGCTATAATGCC
+GAAGCGCTACATCAGTTATTAGGCAATGATTTACGCCCTGAAGCCAGACCAGGTGGCTGG
+GTTGGCGAATGGCTGGCGCAATACCCGGATAATTATGAGGTCGTCAATACATTAGCGCGC
+CAGATTAAGGATATCTGGAAAAATAACCAACATCATAAAGATGGCGGCGAACCCTATAAA
+CTCGCACAACGCCTTGCCATGTTAGCCCATGAAATTGACGCGGTGCCCGCCTGGAATTGT
+AAAAGCGGCAAAGATCGTACAGGGATGATGGATTCAGAAATCAAGCGAGAGCTCATTTCT
+TTCCATCAGACCCATATGTTAAGTGCGCCTGGTAGTCTTCCGGATAGCGGTGGACAGAAA
+ATTTTCCAAAAAGTATTACTGAATAGCGGTAACCTGGAGATTCAGAAACAAAATACGGGC
+GGGGCGGGAAACAAAGTAATGAAAAATTTATCGCCAGAGGTGCTCAATCTTTCCTATCAA
+AAACGAGTTGGGGATGAAAATATTTGG---CAGTCAGTAAAAGGTATTTCTTCATTAATC
+ACATCT
diff --git a/t/data/expected_nuc_multifasta.faa b/t/data/expected_nuc_multifasta.faa
new file mode 100644
index 0000000..951f61b
--- /dev/null
+++ b/t/data/expected_nuc_multifasta.faa
@@ -0,0 +1,48 @@
+>AAAA#74_01075
+CQYHLF*PYWRALPPLLARFLAFLAKNRLTACWLFRWASPQGSCCSSR*WRCCPPR*IPR
+GCRLYWATGCLLSACWATSGWIVCFLTLIRRIWCKKGSSRFPAR*NALRFY*RSALACTT
+FRKESPPLSLPAAILNWVSASHWRWRCTIFLKGWRLPARFMPRRAQNVPRFFGPVSPAWR
+KFLAACWRG*FWAAWFHRSLWRLSWQQSPALWWRSPSMN*CRWQKRSILTITPAMVCFAV
+CPSWGSVSSFCRR*VSV
+>BBBB#75_01314
+MSVPLILTLLAGAATFIGAFLGVLGQKPSNRVLAFSLGFAAGIMLLISLMDAARRVRYRG
+DVACTGLRDVYYRPVGLLRAGSSASSRSSAGSGAKKAAAASRLDKTHCDFIDARH*PAQL
+SGRNRHLCHCQQQS*TGFRHRTGGGVAQYS*RAGGCRPGLCRDGLKTYRDFLGRYLRHGG
+NSWRRAGVADFGQPGFTDRYGGYHGSSRRHYGGALRR*TDAVGKRDRS*Q*PQLWCALRY
+VHHGAQSRHFADDRYRL
+>CCCC#76_00877
+MSVPLILTLLAGAATFIGAFLGVLGQKPSNRVLAFSLGFAAGIMLLISLMEMLPAALDTE
+GMSPVLGYGSLLSACWATSGWIVCFLTLIRRIWCKKGSSRFPAR*NALRFY*RSALACTT
+FRKESPLSLPAAILNWVSASHWRWRCTIFLKGWRLPARFMPRRAQNVPRFFGPVSPAWRK
+FLAACWRG*FWAAWFHRSLWRLSWQQSPALWWRSPSMN*CRWQKRSILTITPAMVCFAVC
+PSWGSVSSFCRR*VSV
+>DDDD#77_01105
+MSVPLILTLLAGAATFIGAFLGVLGQKPSNRVLAFSLGFAAGIMLLISLMEMLPAALDTE
+GMSPVLGYGMFIIGLLGYFGLDRLLPHAHPQDLVQKRQQPLPGSIKRTAILLTLGISLHN
+FPEGIATFVTASSNLELGFGIALAVALHNIPEGLAVAGPVYAATGSKRTAIFWAGISGMA
+EILGGVLAWLILGSLVSPIVMAAIMAAVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCG
+MSIMGLSLVILQTIGIG*
+>EEEE
+MSVPLILTLLAGAATFIGAFLGVLGQKPSNRVLAFSLGFAAGIMLLISLMEMLPAALDTE
+GMSPVLGYGMFIIGLLGYFGLDRLLPHAHPQDLVQKRQQPLPGSIKRTAILLTLGISLHN
+FPEGIATFVTASSNLELGFGIALAVALHNIPEGLAVAGPVYAATGSKRTAIFWAGISGMA
+EILGVLAWLILGSLVSPIVMAAIMAAVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCGM
+SIMGLSLVILQTIGIG*
+>FFFF
+MSVPLILTLLAGAATFIGAFLGVLGQKPSNRVLAFSLGFAAGIMLLISLMEMLPAALDTE
+GMSPVLGYGMFIIGLLGYFGLDRLLPHAHPQDLVQKRQQPLPGSIKRTAILLTLGISLHN
+FPEGIATFVTASSNLELGFGIALAVALHNIPEGLAVAGPVYAATGSKRTAIFWAGISGMA
+EILGGVLAWLILGSLAPIVMAAIMAAVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCGM
+SIMGLSLVILQTIGIG*
+>GGGG
+MSVPLILTLLAGAATFIGAFLGVLGQKPSNRVLAFSLGFAAGIMLLISLMEMLPAALDTE
+GMSPVLGYGMFIIGLLGYFGLDRLLPHAHPQDLVQKRQQPLPGSIKRTAILLTLGISLHN
+FPEGIATFVTASSNLELGFGIALGWRCTIFLKGWRLPARFMPRRAQNVPRFFGPVSPAWR
+KFLAACWRG*FWAAWFHRSLWRLSWQQSPALWWRSPMN*CRWQKRSILTITPAMVCFAVC
+PSWGSVSSFCRR*VSV
+>HHHH
+MSVPLILTLLAGAATFIGAFLGVLGQKPSNRVLAFSLGFAAGIMLLISLMEMLPAALDTE
+GMSPVLGYGMFIIGLLGYFGLDRLLPHASAGSGAKKAAAASRLDKTHCDFIDARH*PAQL
+SGRNRHLCHCQQQS*TGFRHRTGGGVAQYS*RAGGCRPGLCRDGLKTYRDFLGRYLRHGG
+NSWRRAGVADFGQPGFTDRYGGYHGSSRRHYGGALRR*TDAVGKRDRS*Q*PQLWCALRY
+VHHGAQSRHFADDRYRL
diff --git a/t/data/expected_nuc_multifasta_mafft.fa.aln b/t/data/expected_nuc_multifasta_mafft.fa.aln
new file mode 100644
index 0000000..3001679
--- /dev/null
+++ b/t/data/expected_nuc_multifasta_mafft.fa.aln
@@ -0,0 +1,90 @@
+>1
+atgcaaatacagagcttctatcactcagcttcactaaaaacccaggaggcttttaaaagc
+ctacaaaaaaccttatacaacggaatgcagattctctcaggccagggcaaagcgccggct
+aaagcgcccgacgctcgcccggaaattattgtcctgcgagaacctggcgcgacatggggg
+aattatctacagcatcagaagacgtctaaccactcgctgcataacctctataacttacag
+cgcgatcttcttaccgtcgcggcaaccgttctgggtaaacaagacccggttctaacgtca
+atggcaaaccaaatggagttagccaaagttaaagcggaccggccagcaacaaaacaagaa
+gaagctgcggcaaaagcattgaagaaaaatcttatcgaacttattgcagcacgcactcag
+cagcaaaatggcttacctgcaaaagaagctcatcgctttgcggcagtagcgtttagagat
+gctcaggtcaagcagctcaataaccagccctggcaaaccataaaaaatacactcacgcat
+aacgggcatcactataccaacacgcagctccctgccgcagagatgaaaatcggcgcaaaa
+gatatctttcccagtgcttatgagggaaagggcgtatgcagttgggataccaagaatatt
+catcacgccaataatttgtggatgtccacggtgagtgtgcatgaggacggtaaagataaa
+acgcttttttgcgggatacgtcatggtgtgctttccccctatcatgaaaaagatccgctt
+ctgcgtcaggccggcgctgaaaacaaagccaaagaagtattagctgcggcactttttagt
+aaacctgagttgcttaacagagccttagagggcgaagcggtaagcctgaaactggtatcc
+gtcgggttactcaccgcgtcgaatattttcggcaaagagggaactatggtcgaggatcaa
+atgcgcgcatggcaatcgttgacccagccgggaaaaatgattcatttaaaaatccgcaat
+aaagatggcgatctacagacggtaaaaataaaaccggacgtcgccgcatttaatgtgggt
+gttaatgagctggcgctcaagctcggctttggccttaaagcatcagatagctataatgcc
+gaagcgctgcatcagttattaggcaatgatttacgccctgaagccagaccaggtggctgg
+gttggcgaatggctggcgcaatacccggataattatgaggtcgtcaatacattagcgcgc
+cagattaaggatatctggaaaaataaccaacatcataaagatggcggcgaaccctataaa
+ctcgcacaacgccttgccatgttagcccatgaaattgacgcggtgcccgcctggaattgt
+aaaagcggcaaagatcgtacagggatgatggattcagaaatcaagcgagagctcatttct
+ttccatcagacccatatgttaagtgcgcctggtagtcttccggatagcggtggacagaaa
+attttccaaaaagtattactgaatagcggtaacctggagattcagaaacaaaatacgggc
+ggggcgggaaacaaagtaatgaaaaatttatcgccagaggtgctcaatctttcctatcaa
+aaacgagttggggatgaaaatatttggc-gtcagtaaaa--tatttcttcattaatcaca
+tct
+>2
+atgcaaatacagagcttctatcactcagcttcactaaaaacccaggaggcttttaaaagc
+ctacaaaaaaccttatacaacggaatgcagattctctcaggccagggcaaagcgccggct
+aaagcgcccgacgctcgcccggaaattattgtcctgcgagaacctggcgcgacatggggg
+aattatctacagcatcagaagacgtctaaccactcgctgcataacctctataacttacag
+cgcgatcttcttaccgtcgcggcaaccgttctgggtaaacaagacccggttctaacgtca
+atggcaaaccaaatggagttagccaaagttaaagcggaccggccagcaacaaaacaagaa
+gaagctgcggcaaaagcattgaagaaaaatcttatcgaacttattgcagcacgcactcag
+cagcaaaatggcttacctgcaaaagaagctcatcgctttgcggcagtagcgtttagagat
+gctcaggtcaagcagctcaataaccagccctggcaaaccataaaaaatacactcacgcat
+aacgggcatcactataccaacacgcagctccct---gcagagatgaaaatcggcgcaaaa
+gatatctttcccagtgcttatgagggaaagggcgtatgcagttgggataccaagaatatt
+catcacgccaataatttgtgggtgtccacggtgagtgtgcatgaggacggtaaagataaa
+acgcttttttgcgggatacgtcatggtgtgctttccccctatcatgaaaaagatccgctt
+ctgcgtcaggccggcgctgaaaacaaagccaaagaagtattagctgcggcactttttagt
+aaacctgagttgcttaacagagccttagagggcgaagcggtaagcctgaaactggtatcc
+gtcgggttactcaccgcgtcgaatattttcggcaaagagggaactatggtcgaggatcaa
+atgcgcgcatggcaatcgttgacccagccgggaaaaatgattcatttaaaaatccgcaat
+aaagatggcgatctacagacggtaaaaataaaaccggacgtcgccgcatttaatgtgggt
+gttaatgagctggcgctcaagctcggctttggccttaaagcatcagatagctataatgcc
+gaagcgctacatcagttattaggcaatgatttacgccctgaagccagaccaggtggctgg
+gttggcgaatggctggcgcaatacccggataattatgaggtcgtcaatacattagcgcgc
+cagattaaggatatctggaaaaataaccaacatcataaagatggcggcgaaccctataaa
+ctcgcacaacgccttgccatgttagcccatgaaattgacgcggtgcccgcctggaattgt
+aaaagcggcaaagatcgtacagggatgatggattcagaaatcaagcgagagctcatttct
+ttccatcagacccatatgttaagtgcgcctggtagtcttccggatagcggtggacagaaa
+attttccaaaaagtattactgaatagcggtaacctggagattcagaaacaaaatacgggc
+ggggcgggaaacaaagtaatgaaaaatttatcgccagaggtgctcaatctttcctatcaa
+aaacgagttggggatgaaaatatttggcagtcagtaaaaggtatttcttcattaatcaca
+tct
+>3
+atgcaaatacagagcttctatcactcagcttcactaaaaacccaggaggcttttaaaagc
+ctacaaaaaaccttatacaacggaatgcagattctctcaggccagggcaaagcgccggct
+aaagcgcccgacgctcgcccggaaattattgtcctgcgagaacctggcgcgacatggggg
+aattatctacagcatcagaagacgtctaaccactcgctgcataacctctataacttacag
+cgcgatcttcttaccgtcgcggcaaccgttctgggtaaacaagacccggttctaacgtca
+atggcaaaccaaatggagttagccaaggttaaagcggaccggccagcaacaaaacaagaa
+gaagctgcggcaaaagcattgaagaaaaatcttatcgaacttattgcagcacgcactcag
+cagcaaaatggcttacctgcaaaagaagctcatcgctttgcggcagtagcgtttagagat
+gctcaggtcaagcagctcaataaccagccctggcaaaccataaaaaatacactcacgcat
+aacgggcatcactataccaacacgcagctccctgccgcagagatgaaaatcggcgcaaaa
+gatatctttcccagtgcttatgagggaaagggcgtatgcagttgggataccaagaatatt
+catcacgccaataatttgtggatgtccacggtgagtgtgcatgaggacggtaaagataaa
+acgcttttttgcgggatacgtcatggtgtgctttccccctatcatgaaaaagatccgctt
+ctgcgtcaggccggcgctgaaaacaaagccaaagaagtattagctgcggcactttttagt
+aaacctgagttgcttaacagagccttagagggcgaagcggtaagcctgaaactggtatcc
+gtcgggttactcaccgcgtcgaatattttcggcaaagagggaactatggtcgaggatcaa
+atgcgcgcatggcaatcgttgacccagccgggaaaaatgattcatttaaaaatccgcaat
+aaagatggcgatctacagacggtaaaaataaaaccggacgtcgccgcatttaatgtgggt
+gttaatgagctggcgctcaagctcggctttggccttaaagcatcagatagctataatgcc
+gaagcgctacatcagttattaggcaatgatttacgccctgaagccagaccaggtggctgg
+gttggcgaatggctggcgcaatacccggataattatgaggtcgtcaatacattagcgcgc
+cagattaaggatatctggaaaaataaccaacatcataaagatggcggcgaaccctataaa
+ctcgcacaacgccttgccatgttagcccatgaaattgacgcggtgcccgcctggaattgt
+aaaagcggcaaagatcgtacagggatgatggattcagaaatcaagcgagagctcatttct
+ttccatcagacccatatgttaagtgcgcctggtagtcttccggatagcggtggacagaaa
+attttccaaaaagtattactgaatagcggtaacctggagattcagaaacaaaatacgggc
+ggggcgggaaacaaagtaatgaaaaatttatcgccagaggtgctcaatctttcctatcaa
+aaacgagttggggatgaaaatatttggcagtcagtaaaaggtatttcttcattaatcaca
+tct
diff --git a/t/data/expected_number_of_conserved_genes.tab b/t/data/expected_number_of_conserved_genes.tab
new file mode 100644
index 0000000..6957be8
--- /dev/null
+++ b/t/data/expected_number_of_conserved_genes.tab
@@ -0,0 +1,10 @@
+4 2 1
+4 2 1
+4 2 1
+4 2 1
+4 2 1
+4 2 1
+4 2 1
+4 2 1
+4 2 1
+4 2 1
diff --git a/t/data/expected_number_of_conserved_genes_0.6.tab b/t/data/expected_number_of_conserved_genes_0.6.tab
new file mode 100644
index 0000000..e3b3694
--- /dev/null
+++ b/t/data/expected_number_of_conserved_genes_0.6.tab
@@ -0,0 +1,10 @@
+4 2 4
+4 2 4
+4 2 4
+4 2 4
+4 2 4
+4 2 4
+4 2 4
+4 2 4
+4 2 4
+4 2 4
diff --git a/t/data/expected_number_of_genes_in_pan_genome.tab b/t/data/expected_number_of_genes_in_pan_genome.tab
new file mode 100644
index 0000000..bef0a4c
--- /dev/null
+++ b/t/data/expected_number_of_genes_in_pan_genome.tab
@@ -0,0 +1,10 @@
+4 6 7
+4 6 7
+4 6 7
+4 6 7
+4 6 7
+4 6 7
+4 6 7
+4 6 7
+4 6 7
+4 6 7
diff --git a/t/data/expected_number_of_new_genes.tab b/t/data/expected_number_of_new_genes.tab
new file mode 100644
index 0000000..6957be8
--- /dev/null
+++ b/t/data/expected_number_of_new_genes.tab
@@ -0,0 +1,10 @@
+4 2 1
+4 2 1
+4 2 1
+4 2 1
+4 2 1
+4 2 1
+4 2 1
+4 2 1
+4 2 1
+4 2 1
diff --git a/t/data/expected_number_of_unique_genes.tab b/t/data/expected_number_of_unique_genes.tab
new file mode 100644
index 0000000..66c0f85
--- /dev/null
+++ b/t/data/expected_number_of_unique_genes.tab
@@ -0,0 +1,10 @@
+4 4 3
+4 4 3
+4 4 3
+4 4 3
+4 4 3
+4 4 3
+4 4 3
+4 4 3
+4 4 3
+4 4 3
diff --git a/t/data/expected_one_gene_presence_and_absence.Rtab b/t/data/expected_one_gene_presence_and_absence.Rtab
new file mode 100644
index 0000000..79db304
--- /dev/null
+++ b/t/data/expected_one_gene_presence_and_absence.Rtab
@@ -0,0 +1,2 @@
+Gene Gene query_1.fa query_2.fa query_3.fa
+hly 1 0 0
diff --git a/t/data/expected_out_of_order_fasta.fa.sorted.fa b/t/data/expected_out_of_order_fasta.fa.sorted.fa
new file mode 100644
index 0000000..56ce040
--- /dev/null
+++ b/t/data/expected_out_of_order_fasta.fa.sorted.fa
@@ -0,0 +1,10 @@
+>1111
+AAAAAAA
+>2222
+TTTTTTT
+>3333
+GGGGGGG
+>4444
+CCCCCCC
+>5555
+AAAAAAA
diff --git a/t/data/expected_output_core_missing_genes.aln b/t/data/expected_output_core_missing_genes.aln
new file mode 100644
index 0000000..22e00d6
--- /dev/null
+++ b/t/data/expected_output_core_missing_genes.aln
@@ -0,0 +1,10 @@
+>111
+AAAANNNNNNNGGNNNNNXXXXXXX
+>222
+AAAACCCCCCCGGTTTTTXXXXXXX
+>333
+AAAACCCCCCCGGNNNNNXXXXXXX
+>444
+AAAACCCCCCCGGTTTTTXXXXXXX
+>555
+AAAACCCCCCCNNNNNNNXXXXXXX
diff --git a/t/data/expected_output_filtered.fa b/t/data/expected_output_filtered.fa
new file mode 100644
index 0000000..e4321b8
--- /dev/null
+++ b/t/data/expected_output_filtered.fa
@@ -0,0 +1,18 @@
+>2363_5_03666
+AAAAAAAAAAAAAGGGGGGGGGGGGGG
+>4075_2#3_03437
+AAAAAAAAAAAAAGGGGGGGGGGGGGG
+>4075_1#8_03461
+AAAAAAAAAAAAAGGGGGGGGGGGGGG
+>2212_3_02841
+AAAAAAAAAAAAAGGGGGGGGGGGGGG
+>2363_5_00947
+AAAAAAAAAAAAAGGGGGGGGGGGGGG
+>2363_7_00085
+AAAAAAAAAAAAAGGGGGGGGGGGGGG
+>2460_2_00826
+AAAAAAAAAAAAAGGGGGGGGGGGGGG
+>4075_1#6_04091
+AAAAAAAAAAAAAGGGGGGGGGGGGGG
+>4075_1#3_04238
+AAAAAAAAAAAAAGGGGGGGGGGGGGG
diff --git a/t/data/expected_output_groups b/t/data/expected_output_groups
new file mode 100644
index 0000000..726ff09
--- /dev/null
+++ b/t/data/expected_output_groups
@@ -0,0 +1,2 @@
+6259_6#6_02209 6259_7#20_00601 6593_5#7_01700 6630_2#15_02136 6630_4#12_02032 6631_2#21_02147 6631_4#23_02060 6631_7#21_02171 6664_1#10_02278
+1234#12_01975 1234#1_01317 1234#20_01662 1234#3_01167
diff --git a/t/data/expected_output_groups_cdhit b/t/data/expected_output_groups_cdhit
new file mode 100644
index 0000000..6e492aa
--- /dev/null
+++ b/t/data/expected_output_groups_cdhit
@@ -0,0 +1 @@
+3634_6_04078 2212_1_01414 2363_1_00811 2541_2_00696 2541_8_00920 3634_7_00911
diff --git a/t/data/expected_output_groups_group_2.fa b/t/data/expected_output_groups_group_2.fa
new file mode 100644
index 0000000..48be2fc
--- /dev/null
+++ b/t/data/expected_output_groups_group_2.fa
@@ -0,0 +1,19 @@
+>1234#10_00003
+VKTTLSGEIEKLRYEVAVKIVNLQGEVLDLRAEMKINFSEVNSKILKLQFEFEMAKIRKE
+LKTEIADLRAETKTDFLELQKSIVDIYKTISTQTRWILGVATLFAAIGKVIN*
+>1234#10_00018
+MDFSFNLVDNNGTVMRSTFSPIRFFTFSFLWILIDCSSVQKIENFNSVLQEPTFKSLKEE
+EAILGGSSDSDYKIRKTGNTIPVFVLSPIQTPEGMDSKLAAFLSDEVRLIWAKVKGKQVR
+IQEMSWKNPSQLSQELKRLNVDAVIKTDIREVSGKWVVNQKITDPVKEIVYGSVDGSFQS
+PKIEDELQANQAYYLKHGSGVLALDAKSSLVPIWEKSLSSGEIDSILKKSIQGYLSFSAS
+SADTEVLFQGEKIGIASFRNYPLPEGLQQIQITRPGQKDISKSLQIRSGQTISIYQEWKE
+DRTLGGVRILSFPEALQVALDGLKMGETPFYRSNLTPGAMQLELVRETENGPLVYYEGQL
+IVDADKITEIALPYKTDNLISEPEFWKLSGEKGFQAFSGKTLDFQNVSSLPPGWYGVFSA
+PFVPENMELEGIIPITAESDSGIVAISFHTSKKTISLEYEKERLSVYSFPSNGNNVGTYK
+FKKEDKEDGRPFRIITDVKEGTIRLYLGYSKVLEDRLDVSGVWRISILTRGENFSKRSPL
+RNLKIEYKGYK*
+>1234#10_00005
+LTDKLIGFYDPVRMKAERKTSETEIKLEMNLRGTGQYQFDTEIPFFEHMLSHISKHGLID
+LNLWLRGDIEIDCHHSVEDTAILMGATIHKQLGDKAGIFRYGHFTLTMDEVLTTVAVDLG
+GRYFFKYTGPELTGKFGIYDAELSLEFLQKLALNAKMNLHVVVHYGDNKHHVHESIFKAL
+GKALRMAIAQDSAAAGAIPSTKGVLE*
diff --git a/t/data/expected_output_groups_group_2_multi.fa b/t/data/expected_output_groups_group_2_multi.fa
new file mode 100644
index 0000000..e06ec9f
--- /dev/null
+++ b/t/data/expected_output_groups_group_2_multi.fa
@@ -0,0 +1,19 @@
+>1234#10_00003 hypothetical protein
+VKTTLSGEIEKLRYEVAVKIVNLQGEVLDLRAEMKINFSEVNSKILKLQFEFEMAKIRKE
+LKTEIADLRAETKTDFLELQKSIVDIYKTISTQTRWILGVATLFAAIGKVIN*
+>1234#10_00018 putative lipoprotein
+MDFSFNLVDNNGTVMRSTFSPIRFFTFSFLWILIDCSSVQKIENFNSVLQEPTFKSLKEE
+EAILGGSSDSDYKIRKTGNTIPVFVLSPIQTPEGMDSKLAAFLSDEVRLIWAKVKGKQVR
+IQEMSWKNPSQLSQELKRLNVDAVIKTDIREVSGKWVVNQKITDPVKEIVYGSVDGSFQS
+PKIEDELQANQAYYLKHGSGVLALDAKSSLVPIWEKSLSSGEIDSILKKSIQGYLSFSAS
+SADTEVLFQGEKIGIASFRNYPLPEGLQQIQITRPGQKDISKSLQIRSGQTISIYQEWKE
+DRTLGGVRILSFPEALQVALDGLKMGETPFYRSNLTPGAMQLELVRETENGPLVYYEGQL
+IVDADKITEIALPYKTDNLISEPEFWKLSGEKGFQAFSGKTLDFQNVSSLPPGWYGVFSA
+PFVPENMELEGIIPITAESDSGIVAISFHTSKKTISLEYEKERLSVYSFPSNGNNVGTYK
+FKKEDKEDGRPFRIITDVKEGTIRLYLGYSKVLEDRLDVSGVWRISILTRGENFSKRSPL
+RNLKIEYKGYK*
+>1234#10_00005 imidazoleglycerol-phosphate dehydratase or histidinol-phosphatase
+LTDKLIGFYDPVRMKAERKTSETEIKLEMNLRGTGQYQFDTEIPFFEHMLSHISKHGLID
+LNLWLRGDIEIDCHHSVEDTAILMGATIHKQLGDKAGIFRYGHFTLTMDEVLTTVAVDLG
+GRYFFKYTGPELTGKFGIYDAELSLEFLQKLALNAKMNLHVVVHYGDNKHHVHESIFKAL
+GKALRMAIAQDSAAAGAIPSTKGVLE*
diff --git a/t/data/expected_output_groups_group_5.fa b/t/data/expected_output_groups_group_5.fa
new file mode 100644
index 0000000..4ff2725
--- /dev/null
+++ b/t/data/expected_output_groups_group_5.fa
@@ -0,0 +1,9 @@
+>1234#10_00016
+MKVTHSCLEFDSIEGLIDFAREFETGSMIRFLSPIEDNSGNVLVKEEVQVKESTLARLKD
+IKGQYTPKFEVKLNKELLEQIQNILAIKIVNQLKVTDMKFLKFMYENTNYNFKGIIRNSL
+LSKKTTLTLLKVYNQNLNFFKYISELGLLSLGIVMIPDTMRFRLLRRYAFTAGILMDVPR
+IGVDKFTKLPSDDNEKVRVAHKCSDILQKLDLIEFTYGSISNHMPLGMIEDSTSSDKAAP
+GENIDETFLDDIISNDGESDSKVDGSREDAIPEKSYDIFQALLTDALKLARYIANVSHNA
+VDKDYVMEELVYYIAYNTSKKYFDELLANPLVATFKEFEVNVKRLRKIAEVEMKCVYPPS
+AWAYPKPKSSQVLCKNKVWDCPNIVMGWDIHVITAQEAFGWVGTSLPVDNYPKCRLEEEL
+DEIMVEPEKPKKK*
diff --git a/t/data/expected_output_groups_group_5_multi.fa b/t/data/expected_output_groups_group_5_multi.fa
new file mode 100644
index 0000000..7d344e3
--- /dev/null
+++ b/t/data/expected_output_groups_group_5_multi.fa
@@ -0,0 +1,9 @@
+>1234#10_00016 hypothetical protein
+MKVTHSCLEFDSIEGLIDFAREFETGSMIRFLSPIEDNSGNVLVKEEVQVKESTLARLKD
+IKGQYTPKFEVKLNKELLEQIQNILAIKIVNQLKVTDMKFLKFMYENTNYNFKGIIRNSL
+LSKKTTLTLLKVYNQNLNFFKYISELGLLSLGIVMIPDTMRFRLLRRYAFTAGILMDVPR
+IGVDKFTKLPSDDNEKVRVAHKCSDILQKLDLIEFTYGSISNHMPLGMIEDSTSSDKAAP
+GENIDETFLDDIISNDGESDSKVDGSREDAIPEKSYDIFQALLTDALKLARYIANVSHNA
+VDKDYVMEELVYYIAYNTSKKYFDELLANPLVATFKEFEVNVKRLRKIAEVEMKCVYPPS
+AWAYPKPKSSQVLCKNKVWDCPNIVMGWDIHVITAQEAFGWVGTSLPVDNYPKCRLEEEL
+DEIMVEPEKPKKK*
diff --git a/t/data/expected_output_merged.aln b/t/data/expected_output_merged.aln
new file mode 100644
index 0000000..100dd07
--- /dev/null
+++ b/t/data/expected_output_merged.aln
@@ -0,0 +1,8 @@
+>1111_1#1
+AAAAA-CCCC----TTTTTTTTTTTTTTT
+>2222_2#2
+CCCCC-AAAA----AAAAAAAAAAAAAAA
+>3333_3#3
+TTTTT-GGGG----CCCCCCCCCCCCCCC
+>4444_4#4
+GGGGG-TTTT----GGGGGGGGGGGGGGG
diff --git a/t/data/expected_output_merged_sparse.aln b/t/data/expected_output_merged_sparse.aln
new file mode 100644
index 0000000..ae71404
--- /dev/null
+++ b/t/data/expected_output_merged_sparse.aln
@@ -0,0 +1,8 @@
+>1111_1#1
+CCCC-----AAAA-AAAAA--AAAA-
+>2222_2#2
+AAAA-----TTTT-CCCCC--TTTT-
+>3333_3#3
+GGGG----NNNNNNTTTTT-NNNNNN
+>4444_4#4
+TTTT-----CCCC-GGGGG--CCCC-
diff --git a/t/data/expected_pan_genome.fa b/t/data/expected_pan_genome.fa
new file mode 100644
index 0000000..5354813
--- /dev/null
+++ b/t/data/expected_pan_genome.fa
@@ -0,0 +1,33 @@
+>1234#10_00016
+MKVTHSCLEFDSIEGLIDFAREFETGSMIRFLSPIEDNSGNVLVKEEVQVKESTLARLKD
+IKGQYTPKFEVKLNKELLEQIQNILAIKIVNQLKVTDMKFLKFMYENTNYNFKGIIRNSL
+LSKKTTLTLLKVYNQNLNFFKYISELGLLSLGIVMIPDTMRFRLLRRYAFTAGILMDVPR
+IGVDKFTKLPSDDNEKVRVAHKCSDILQKLDLIEFTYGSISNHMPLGMIEDSTSSDKAAP
+GENIDETFLDDIISNDGESDSKVDGSREDAIPEKSYDIFQALLTDALKLARYIANVSHNA
+VDKDYVMEELVYYIAYNTSKKYFDELLANPLVATFKEFEVNVKRLRKIAEVEMKCVYPPS
+AWAYPKPKSSQVLCKNKVWDCPNIVMGWDIHVITAQEAFGWVGTSLPVDNYPKCRLEEEL
+DEIMVEPEKPKKK*
+>1234#10_00017
+MKRYLSIVILCTFAMLLLVCSTNKSSGSDQVKTESNATSARIVWLLGDVKILSDSGEKKA
+ELGASLSSTDRVVTGPNGGAEIMVADSGIIKMSKNSDIEISSLMNPNGSDTNVQVNYGKI
+VTMVKKGQKTTEFTVSTPTALAGVRGTSFLTSVESPEGSKINCAKANCTVRFAVIEGTIA
+VSKKGESSEVILSKNRELRIEKNQKLTDKLIRSLQNDSLSEMKELIVLHKNETFEYGKLV
+EELKSSSEELKILSQSGSVEEVKAAFQKREADRNNADEITKTAKAVNETKYVQQDVQKEK
+LKLNPKETF*
+>1234#10_00001
+MSKHGFFQITQKLFLRKGDELLILRDRKSGLGDLPGGRMNENEFFEDWSLSMQREIEEEL
+GSQVQIRVSTKPLFIHKHKVNEGNFPCIIIAYHADYLGGDIILSDEHDYISWEKVQTYEP
+SPLFTEYMLDAVNLYLKEYAPLVH*
+>1234#10_00003
+VKTTLSGEIEKLRYEVAVKIVNLQGEVLDLRAEMKINFSEVNSKILKLQFEFEMAKIRKE
+LKTEIADLRAETKTDFLELQKSIVDIYKTISTQTRWILGVATLFAAIGKVIN*
+>1234#10_00005
+LTDKLIGFYDPVRMKAERKTSETEIKLEMNLRGTGQYQFDTEIPFFEHMLSHISKHGLID
+LNLWLRGDIEIDCHHSVEDTAILMGATIHKQLGDKAGIFRYGHFTLTMDEVLTTVAVDLG
+GRYFFKYTGPELTGKFGIYDAELSLEFLQKLALNAKMNLHVVVHYGDNKHHVHESIFKAL
+GKALRMAIAQDSAAAGAIPSTKGVLE*
+>1234#10_00006
+MIAILDYGMGNIHSCLKAVSLYTKDFVFTKDHSTIENSKALILPGDGHFDKAMENLNSTG
+LRKTIDKHVTSGKPLFGICIGFQILFESSEEIAQGSKKEQIEGLGYIKGKIKKFHGKDFK
+VPHIGWNRLQIRRKDKSVLLKGIGDQSFFYFIHSYRPTDAEGNAITGLCDYYQEKFPAVV
+EKNNIFGTQFHPEKSHTHGLKLLENFIRFI*
diff --git a/t/data/expected_pan_genome_one_gene_per_fasta.fa b/t/data/expected_pan_genome_one_gene_per_fasta.fa
new file mode 100644
index 0000000..b788b9b
--- /dev/null
+++ b/t/data/expected_pan_genome_one_gene_per_fasta.fa
@@ -0,0 +1,33 @@
+>1234#10_00001 nudix hydrolase
+MSKHGFFQITQKLFLRKGDELLILRDRKSGLGDLPGGRMNENEFFEDWSLSMQREIEEEL
+GSQVQIRVSTKPLFIHKHKVNEGNFPCIIIAYHADYLGGDIILSDEHDYISWEKVQTYEP
+SPLFTEYMLDAVNLYLKEYAPLVH*
+>1234#10_00003 hypothetical protein
+VKTTLSGEIEKLRYEVAVKIVNLQGEVLDLRAEMKINFSEVNSKILKLQFEFEMAKIRKE
+LKTEIADLRAETKTDFLELQKSIVDIYKTISTQTRWILGVATLFAAIGKVIN*
+>1234#10_00005 imidazoleglycerol-phosphate dehydratase or histidinol-phosphatase
+LTDKLIGFYDPVRMKAERKTSETEIKLEMNLRGTGQYQFDTEIPFFEHMLSHISKHGLID
+LNLWLRGDIEIDCHHSVEDTAILMGATIHKQLGDKAGIFRYGHFTLTMDEVLTTVAVDLG
+GRYFFKYTGPELTGKFGIYDAELSLEFLQKLALNAKMNLHVVVHYGDNKHHVHESIFKAL
+GKALRMAIAQDSAAAGAIPSTKGVLE*
+>1234#10_00006 imidazole glycerol phosphate synthase subunit HisH
+MIAILDYGMGNIHSCLKAVSLYTKDFVFTKDHSTIENSKALILPGDGHFDKAMENLNSTG
+LRKTIDKHVTSGKPLFGICIGFQILFESSEEIAQGSKKEQIEGLGYIKGKIKKFHGKDFK
+VPHIGWNRLQIRRKDKSVLLKGIGDQSFFYFIHSYRPTDAEGNAITGLCDYYQEKFPAVV
+EKNNIFGTQFHPEKSHTHGLKLLENFIRFI*
+>1234#10_00016 hypothetical protein
+MKVTHSCLEFDSIEGLIDFAREFETGSMIRFLSPIEDNSGNVLVKEEVQVKESTLARLKD
+IKGQYTPKFEVKLNKELLEQIQNILAIKIVNQLKVTDMKFLKFMYENTNYNFKGIIRNSL
+LSKKTTLTLLKVYNQNLNFFKYISELGLLSLGIVMIPDTMRFRLLRRYAFTAGILMDVPR
+IGVDKFTKLPSDDNEKVRVAHKCSDILQKLDLIEFTYGSISNHMPLGMIEDSTSSDKAAP
+GENIDETFLDDIISNDGESDSKVDGSREDAIPEKSYDIFQALLTDALKLARYIANVSHNA
+VDKDYVMEELVYYIAYNTSKKYFDELLANPLVATFKEFEVNVKRLRKIAEVEMKCVYPPS
+AWAYPKPKSSQVLCKNKVWDCPNIVMGWDIHVITAQEAFGWVGTSLPVDNYPKCRLEEEL
+DEIMVEPEKPKKK*
+>1234#10_00017 LipL45-like lipoprotein
+MKRYLSIVILCTFAMLLLVCSTNKSSGSDQVKTESNATSARIVWLLGDVKILSDSGEKKA
+ELGASLSSTDRVVTGPNGGAEIMVADSGIIKMSKNSDIEISSLMNPNGSDTNVQVNYGKI
+VTMVKKGQKTTEFTVSTPTALAGVRGTSFLTSVESPEGSKINCAKANCTVRFAVIEGTIA
+VSKKGESSEVILSKNRELRIEKNQKLTDKLIRSLQNDSLSEMKELIVLHKNETFEYGKLV
+EELKSSSEELKILSQSGSVEEVKAAFQKREADRNNADEITKTAKAVNETKYVQQDVQKEK
+LKLNPKETF*
diff --git a/t/data/expected_pan_genome_reference.fa b/t/data/expected_pan_genome_reference.fa
new file mode 100644
index 0000000..61a7a0d
--- /dev/null
+++ b/t/data/expected_pan_genome_reference.fa
@@ -0,0 +1,1466 @@
+>11111_1#11_04055
+ATGCTTCCGGTCACCTACAGATTAATACCTCAAAGCGGAGTATCCACATATGGATTAAAT
+ACCGCAGATACACCTGTTTTCCCCGATATTCCCGAACATGCACCAAACCCCTCACGGCTA
+CGCCTTGCTCATGACAGCCTTGCCATAAACAGTGAATTCCGTCTGGAGCCAGAGTGTGTG
+GTGGAGTACCTTATCTCAGGCGCGGGTGGAATAGACCCTGATACAGAAATTGATGACGAC
+ACTTATGACGAATGCTACGATGAACTATCCTCCGTACTTCAAAATGCGTATACCCAAAGC
+GAAACATTCCGCAGACTGATGAATTACGCATATGAAAAAGAACTACATGATGTGGAGCAG
+CGCTGGCTACCGGGGGCAGGCGAAGCCTTTGAAACTACCGTGGCTCAGGAACACTTCAAA
+CTTTCAGAAGGCAGGAAAGTTATTTGTCTCAATCTGGACGATTCTGATGATTCATATACC
+GAACATTATGAAAGTAACGAAGGAAGACAACTTTTTGACACAAAACGTTCATTTACTCAT
+GAAGTTGTACATGCACTGACCCATCTTCAGGATAAAGAAGAAAATCATCCAAGAGGCCCT
+GTTGTCGAATATACCAACATTATTCTGAAAGAGATGGGGCATCCTTCACCTCCCAGAATG
+GTCTACATCTTCAATAAATAG
+>11111_1#11_04056
+ATGCCAATAACTAACGCGTCCCCAGAAAATATATTAAGATATTTGCATGCGGCCGGTACC
+GGTACGAAAGAAGCAATGAAAAGTGCAACTTCACCACGCGGTATACTGGAATGGTTTGTC
+AATTTTTTTACCTGTGGTGGAGTAAGAAGAAGCAATGAAAGATGCTTTTGGGAGGTAATT
+GGAAAACTGACCACATCATTATTATATGTAAATAAAGATGCTTTCTTCGATGGTAATAAA
+ATATTTCTGGAGGATGTCAACGGGTGTACTATATGTCTGTCATGTGGAGCAGCATCCGAA
+AATACGGATCCCATGGTCACTATTGAAGTGAACAAAAATGGAAAAACTGTAACGGATAAA
+GTTGATAGTGAGAGATTTTGGAATGTATGTCGAATGTTAAAACTGATGAGTAAACATAAT
+ATACAACAGCCTGATTCACTTATAACCGAGGATGGTTTTCTGAACCTGCGCGGAGTAAAC
+CTAGCTCATAAAGATTTCCAGGGAGAAGATTTGTCAGACATAGATGCTTCTAATGCAGAT
+TTCCGTGAAACAAATCTATCTAATGTAAATTTAGTCGGTGCAAATTTGTGTTGTGCAAAT
+CTACACGCTGTAAATCTAATGGGTTCAAACATGACTAAAGCAAACCTGACTCACGCAGAC
+CTGACTTGCGCTAACATGTCCGGTGTAAACTTAACCGCTGCAATTCTATTCGGCTCAGAC
+TTAACTGACACCAAACTAAATGGTGCAAAATTAGATAAGATAGCTCTAACTTTAGCGAAA
+GCATTAACAGGAGCCGATCTGACAGGTAGTCAACATACCCCTACTCCACTCCCGGATTAC
+AATGATAAAACGCTTTTCCCCCATCCAATATTTTAG
+>11111_1#11_04058
+ATGGAAAGTCTATTAAATCGTTTATATGACGCGTTAGGCCTGGATGCGCCAGAAGATGAG
+CCACTGCTTATCATTGATGATGGGATACAGGTTTATTTTAATGAATCCGATCATACACTG
+GAAATGTGCTGTCCCTTTATGCCACTGCCTGACGACACTCTGACTTTGCAGCATTTTTTA
+CGTCTTAACTACGCCAGCGCCGTCACTATCGGCGCTGATGCAGACAATACTGCTTTAGTG
+GCGCTTTATCGCTTGCCGCAAACCAGTACCGAAGAAGAGGCGCTCACTGGTTTTGAATTA
+TTCATTTCAAACGTGAAGCAATTGAAAGAGCATTATGCATAA
+>11111_1#11_04059
+ATGCAAATACAGAGCTTCTATCACTCAGCTTCACTAAAAACCCAGGAGGCTTTTAAAAGC
+CTACAAAAAACCTTATACAACGGAATGCAGATTCTCTCAGGCCAGGGCAAAGCGCCGGCT
+AAAGCGCCCGACGCTCGCCCGGAAATTATTGTCCTGCGAGAACCTGGCGCGACATGGGGG
+AATTATCTACAGCATCAGAAGACGTCTAACCACTCGCTGCATAACCTCTATAACTTACAG
+CGCGATCTTCTTACCGTCGCGGCAACCGTTCTGGGTAAACAAGACCCGGTTCTAACGTCA
+ATGGCAAACCAAATGGAGTTAGCCAAAGTTAAAGCGGACCGGCCAGCAACAAAACAAGAA
+GAAGCTGCGGCAAAAGCATTGAAGAAAAATCTTATCGAACTTATTGCAGCACGCACTCAG
+CAGCAAAATGGCTTACCTGCAAAAGAAGCTCATCGCTTTGCGGCAGTAGCGTTTAGAGAT
+GCTCAGGTCAAGCAGCTCAATAACCAGCCCTGGCAAACCATAAAAAATACACTCACGCAT
+AACGGGCATCACTATACCAACACGCAGCTCCCTGCCGCAGAGATGAAAATCGGCGCAAAA
+GATATCTTTCCCAGTGCTTATGAGGGAAAGGGCGTATGCAGTTGGGATACCAAGAATATT
+CATCACGCCAATAATTTGTGGATGTCCACGGTGAGTGTGCATGAGGACGGTAAAGATAAA
+ACGCTTTTTTGCGGGATACGTCATGGTGTGCTTTCCCCCTATCATGAAAAAGATCCGCTT
+CTGCGTCAGGCCGGCGCTGAAAACAAAGCCAAAGAAGTATTAGCTGCGGCACTTTTTAGT
+AAACCTGAGTTGCTTAACAGAGCCTTAGAGGGCGAAGCGGTAAGCCTGAAACTGGTATCC
+GTCGGGTTACTCACCGCGTCGAATATTTTCGGCAAAGAGGGAACTATGGTCGAGGATCAA
+ATGCGCGCATGGCAATCGTTGACCCAGCCGGGAAAAATGATTCATTTAAAAATCCGCAAT
+AAAGATGGCGATCTACAGACGGTAAAAATAAAACCGGACGTCGCCGCATTTAATGTGGGT
+GTTAATGAGCTGGCGCTCAAGCTCGGCTTTGGCCTTAAAGCATCAGATAGCTATAATGCC
+GAAGCGCTACATCAGTTATTAGGCAATGATTTACGCCCTGAAGCCAGACCAGGTGGCTGG
+GTTGGCGAATGGCTGGCGCAATACCCGGATAATTATGAGGTCGTCAATACATTAGCGCGC
+CAGATTAAGGATATCTGGAAAAATAACCAACATCATAAAGATGGCGGCGAACCCTATAAA
+CTCGCACAACGCCTTGCCATGTTAGCCCATGAAATTGACGCGGTGCCCGCCTGGAATTGT
+AAAAGCGGCAAAGATCGTACAGGGATGATGGATTCAGAAATCAAGCGAGAGCTCATTTCT
+TTCCATCAGACCCATATGTTAAGTGCGCCTGGTAGTCTTCCGGATAGCGGTGGACAGAAA
+ATTTTCCAAAAAGTATTACTGAATAGCGGTAACCTGGAGATTCAGAAACAAAATACGGGC
+GGGGCGGGAAACAAAGTAATGAAAAATTTATCGCCAGAGGTGCTCAATCTTTCCTATCAA
+AAACGAGTTGGGGATGAAAATATTTGGCAGTCAGTAAAAGGTATTTCTTCATTAATCACA
+TCTTGA
+>11111_1#11_04060
+ATGAAAAAGTATCTTGCTTTCGCCGTTACGCTGCTGGGTATGGGTAAAGTCATCGCCTGT
+ACTACCCTTTTGGTAGGCAATCAGGCTTCGGCTGACGGCTCCTTTATTATCGCGCGCAAC
+GAGGATGGCTCGGCAAATAACGCCAAGCATAAGGTTATTCATCCCGTCGCGTTTCATCAA
+CAAGGCGAGTATAAAGCACATCGCAACAATTTTAGCTGGCCGCTTCCGGAGACAGCGATG
+CGCTATACGGCGATTCATGACTTTGATACTAACGATAACGCCATGGGTGAAGCCGGTTTC
+AATTCGGCGGGCGTCGGAATGAGCGCAACGGAAACCATTTACAACGGCAGAGCGGCGCTG
+GCTGCCGATCCTTACGTGACAAAAACGGGAATCACGGAAGACGCCATTGAGTCCGTGATC
+CTGCCAGTGGCGCAATCGGCGCGTCAGGGCGCCAAATTACTGGGAGATATTATTGAACAA
+AAAGGCGCGGGCGAAGGTTTCGGCGTCGCGTTTATTGATAGCAAAGAGATATGGTATCTG
+GAGACGGGAAGCGGACATCAATGGCTGGCAGTACGACTTCCGGCAGATAGCTATTTCGTT
+TCCGCCAATCAGGGACGTTTACGCCATTACGATCCGAATGATAACGCGAATTATATGGCG
+TCACCAACGTTAGTAAGCTTTGCGAAAAAGCAGGGATTATATGATCCGGCCCGCGGCGAA
+TTCGACTTTCATCAAGCCTATTCGCAGGATAACAAAAACGATACCACCTATAATTATCCG
+CGCGTCTGGACGCTACAACACCAGTTTAATCCGCATCTGGATACGGTCGTTAGCGAAGGG
+GAAACATTTTCTGTTTTTTTAACGCCAATAACGAAGATCAGCGTGGCGGCAGTAAAAAAC
+GCGTTACGCAATCACTATCAGGGAACGTCGCACGACCCTTATGCCAGTCATAATCCACAA
+GAACCATGGCGACCTATATCCGTTTTTCGTACCCAGGAGTCACATATTTTACAGGTCAGA
+CCGAAATTACCGCAGGCTATCGGCAACGTAGAATACATCGCCTATGGAATGCCATCTCTT
+AGCGTCTATCTCCCCTATTACCAGGGGATGCGTCATTATCAACCCGGAGATGATAAAGGA
+ACCGATCGGGCGAGCAACGACTCTACCTACTGGACATTCCGCACGCTGCAAACACTGGTT
+ATGCAAGACTACAATACGTTTGCGCCAGATGTGCAACATGCCTGGAAAACATTTGAACAG
+CAAACAGCTAAGCAACAGTATAAGATGGAGCAGAGCTATCTGAGATTATATGCGTCGCAT
+CCGAAAGAAGCACAACGCTTACTGCAAAATTTTGAAGATAAAACGATGCAAAATGCGCAG
+ACGCTCGCCCGTCGCCTGACCAATAATATTATTACGACAATGACTTACCGCACAGATATG
+AAATATCACTTTTCAAGTACGCAGCCATAA
+>11111_1#11_04061
+ATGGTTAAGTTATCAATGACGCTGCGCCTGACAATTTCTTTTATCGCCATACTTATCCTC
+GCCTGTACCGGCATTAGCTGGACGCTCTATAACGCGCTGAGCAAAGAATTAACGTATCGG
+GATGATATGACGCTAATAAATCGGGCGGCGCAAATGCAGCAACTGTTACTGGATGGCGCC
+AGGCCGGAAAATCTGCCGCTCTATTTCAATCGGATGGTGGATACGAAGCAGGATATCTTA
+TTGATCCACTCAGCAACAGGCCATAATGTTGCGATTAATCATAGCGGCATCCCCGACCAA
+CGCTTTAACGAGATTCCGCTGGCTAAAAACATCACCCGCGAAACCTTATTTCGCCAGGCG
+GTACAAGGCACGGAGCTGACCGCGGTACGAGTAAACGCCAGAAGCGGCGATAACCCGCTG
+ACCCTTACTATTGCCAGGCTGGCGACGGAAAGGCGGCAAATGCTGGCGCAATATCGCCGC
+AACAGTTTGCTGATTAGCCTTATCGCGATCCTCGTCTGTTCGGCGCTCAGTCCATTAGTC
+ATCAGAAACGGGCTGCGGGCCATTACGTCGCTCAGCCGACTCACCGCGGCGACAGATAGC
+GGCACACTTCGCCAGCCGCTGGCGGAACAGGCGTTACCCGTCGAGCTCAGGCCGCTTGGG
+CAAGCGCTAAATACCATGCGCCAGAAGCTTTCCGACGATTTTGAACGCCTGAACCAATTT
+GCCGACGATCTGGCGCATGAGCTGCGCACGCCGGTTAATATTTTACTGGGGAAGAATCAG
+GTTATGCTGAGTCAGGAACGCAGCGCCGAAGAGTATCAACAAGCCCTTGTCGATAATATT
+GAAGAGCTGGAGGGACTGTCGCGACTGACAGAAAATATTCTCTTTCTGGCACGCGCGGAG
+CACCAGAATATAGCGGTAAAAAAACAGCCTGTTTCGCTCAATGCGCTGGTCGAAAATATG
+CTGGATTATCTTAGCCCCCTTGCCGAAGAGAAGCACATCTGTTTTATAAATCAATGTCAG
+GGAACGGTATGGGCTGACGAAATATTATTACAAAGAGTGCTCTCAAACCTGCTGACGAAT
+GCCATCCGTTATTCTGATGAAAACGCCGTGATACGTATTGAAAGCGCTTATGATGATAAC
+GTTGCAGAAATTCGGGTCGCTAATCCGGGCAGCCCCACCGCCGATGCGGATAAGCTTTTC
+CGGCGTTTTTGGCGAGGAGATAATGCCCGCTACACTGCCGGTTTCGGCCTGGGGTTATCG
+TTAGTTAACGCGATTGCCCTATTGCACGGTGGCTCGGCATCTTACCGCTATGCCGATGAA
+CATAATATCTTTTCGGTTCGTCTGCCTGATAGCGGTGATAGCTAA
+>11111_1#11_04062
+ATGTCATCTTGTTGGAGATTTACGGATTCGCTAACAAGCCTATGGCATACTGCGTTGATG
+AAGATTTTATTGATTGAAGATAACCAGAAAACCATTGAGTGGGTACGTCAGGGACTCACG
+GAGGCAGGCTATGTGGTTGATTATGCCTGTGATGGACGAGACGGATTACACCTAGCCCTT
+CAGGAACATTATTCATTGATTATTCTTGATATTATGCTGCCGGGGCTTGATGGATGGCAG
+GTTTTACGCGCGTTGCGCACTGCATATCAGCCCCCTGTTATTTGCCTGACGGCGCGCGAC
+TCGGTTGAGGATCGCGTCAAAGGTCTTGAGGCGGGCGCTAATGATTACCTTGTTAAGCCT
+TTTTCCTTCGCCGAACTGCTGGCCCGGGTGAGAGCTCAACTCAGACAGCATGTCCCGGTC
+TTTACCCGACTGACGATCAATGGTCTGGACATGGATGCCACAAAGCAATCGGTGTTACGA
+AATGGCAAACCGATTTCCCTGACCCGCAAAGAATTCCTGCTCCTCTGGTTACTGGCGTCC
+CGGGCAGGGGAAATCGTGCCCCGAACCGCGATCGCCAGCGAAGTTTGGGGAATTAACTTT
+GATAGTGAAACCAACACCGTTGATGTCGCGATTCGTCGGCTGCGCGCCAAAGTAGACGAT
+CCATTTGAAAAGAAGCTCATTATGACCGTCCAGGGGATGGGTTATCGATTACAGGCGGAA
+ACGTCGCAGAATGGTTAA
+>11111_1#11_04063
+ATGAAACGATATATACTGGCTACCGCGATAGCGTCTCTTGTTGCAGCCCCGGCAATGGCG
+CTGGCCGCTGGCAGCAATATTCTCAGCGTACATATTCTCGATCAGCAAACAGGCAAACCA
+GCGCCCGGCGTGGAGGTGGTACTGGAGCAGAAAAAGGATAACGGATGGACGCAATTAAAC
+ACCGGGCATACCGACCAGGATGGACGAATTAAAGCACTGTGGCCCGAAAAAGCTGCCGCG
+CCGGGGGATTATCGCGTTATTTTTAAAACCGGCCAGTATTTTGAAAGTAAAAAACTGGAC
+ACGTTTTTCCCGGAGATTCCCGTCGAGTTTCATATCAGCAAAACGAATGAGCACTATCAT
+GTGCCGCTGTTATTAAGTCAGTATGGTTATTCAACCTATCGCGGGAGCTAA
+>11111_1#11_04064
+ATGCAAGTAGATGAACAACGTCTGCGTTTTCGCGATGCGATGGCAAGTCTGGCGGCAGCG
+GTCAACATCGTAACCACGGCGGGTCACGCCGGACGCTGCGGTATCACCGCAACAGCGGTT
+TGCTCAGTCACTGATACGCCGCCCTCCGTGATGGTATGTATTAATGCCAATAGCGCCATG
+AACCCCGTTTTTCAGGGCAACGGCAGGCTGTGCATTAATGTACTTAACCATGAGCAGGAG
+CTGATGGCGCGCCACTTTGCCGGTATGACGGGGATGGCGATGGAGGAGCGTTTTCACCAG
+CCATGTTGGCAAAACGGGCCGCTGGGCCAGCCGGTACTTAACGGCGCGCTGGCCAGTCTT
+GAAGGCGAGATCAGCGAGGTACAAACCATTGGCACGCATCTGGTGTATCTGGTGGCGATC
+AAAAATATTATTCTTAGCCAGGAGGGGCATGGCCTGATTTATTTCAAACGCCGTTTTCAT
+CCGGTCAGACTTGAGATGGAAGCGCCTGTTTAA
+>11111_1#11_04065
+ATGGGACGCACACCGGATTACAAAGCCGCCTTTGGCTGCGCTCTGGGCGCTAACCCAGCC
+TTCTACGGCCAGTTTGAGCAGAACGCCCGTAACTGGTACACCCGTATTCAGGAGACCGGC
+CTGTACTTTAACCATGCAATCGTCAACCCGCCCATTGACCGCCACAAACCTGCCGACGAA
+GTGAAAGACGTCTATATCAAGCTGGAGAAAGAGACGGACGCCGGGATTATTGTCAGCGGG
+GCGAAAGTTGTCGCCACTAACTCCGCCCTGACTCACTACAACATGATTGGTTTCGGCTCA
+GCCCAGGTGATGGGCGAAAACCCGGATTTTGCTCTGATGTTTGTCGCGCCAATGGATGCC
+GAAGGCGTAAAACTTATTTCGCGCGCCTCGTATGAAATGGTCGCGGGCGCGACGGGCTCG
+CCGTTTGATTATCCCCTCTCCAGCCGTTTTGATGAAAACGATGCCATTCTGGTGATGGAC
+AAGGTGCTGATCCCGTGGGAAAACGTATTAATTTACCGTGATTTCGATCGTTGTCGTCGC
+TGGACGATGGAAGGCGGCTTTGCCCGTATGTATCCACTGCAAGCCTGTGTTCGTCTGGCG
+GTAAAACTTGATTTCATTACCGCGCTGCTGAAAAAATCGCTCGAATGTACGGGTACCGTA
+GAGTTCCGGGGCGTGCAGGCCGATCTCGGCGAAGTCGTGGCCTGGCGCAATATGTTCTGG
+GCATTGAGCGATTCTATGTGTTCTGAAGCAACCCCGTGGGTAAACGGCGCCTGGCTACCG
+GACCACGCCGCGCTGCAAACCTATCGTGTGATGGCCCCAATGGCCTACGCGAAAATTAAA
+AATATTATTGAACGTAACGTTACCAGCGGCCTGATTTACCTGCCTTCCAGCGCCCGCGAT
+CTGAATAATCCGCAAATCGACCAGTACCTGGCGAAATACGTACGCGGCTCTAACGGAATG
+GACCATGTTGAACGTATCAAAATTCTTAAATTGATGTGGGATGCCATCGGCAGCGAGTTT
+GGCGGTCGCCATGAGCTGTACGAGATTAACTACTCGGGCAGCCAGGATGAAATTCGTCTG
+CAGTGTCTGCGTCAGGCCCAGAGCTCCGGCAATATGGATAAGATGATGGCAATGGTCGAT
+CGCTGCCTCTCCGAATACGATCAGAATGGCTGGACGGTTTCGCATTTGCACAATAACGAC
+GACATCAATCAACTGGATAAGCTGCTGAAATAA
+>11111_1#11_04066
+ATGCATGATTCATTAACCATCGCCTTGCTTCAGGCGCGCGAAGCGGCAATGACCTATTTC
+CGCCCCATCGTTAAAAGCCACAATCTGACCGACCAGCAATGGCGCATTGTGCGAATCCTG
+GCCGATAGCCCCTCTATGGATTTTCACGAGCTGGCCTTTCGTACCTGTATTTTGCGTCCA
+AGTCTGACCGGAATATTGACGCGCATGGAGCGAGACGGACTGGTGTTGCGACTCAAGCCG
+GTTAACGATCAGCGTAAGTTATATGTCATGTTGACGGAGCAGGGACAAACGTTGTACGCC
+CGTGCCCGGAGCGAGGTAGAAGAGGCTTATCGAAAAATTGAGGCCGATTTCACGCCCGAA
+AAAACACAGCAATTGATGCTGCTGCTGGACGATCTTATTGCTCTGGGGCGCCAGCATCCT
+GATAGCGAAGCGGAAGCATAG
+>11111_1#11_04067
+ATGAAGGGTACTGTTTTCGCCGTTGCGTTAAACCATCGCAGCCAGCTTGATGCCTGGCAA
+GAGGCTTTCTCTCAGCCTCCCTATAATGCGCCGCCTAAAACCGCAGTGTGGTTCATCAAG
+CCGCGTAATACGGTGATTCGTCACGGCGAACCCATTCCTTATCCGCAGGGAGAAAAGGTA
+CTGAGCGGCGCGACAGTGGCGCTCATTGTGGGGAAAACCGCCAGCCGGATACGCCCTGAA
+GCGGCGGCGGACTATATCGCCGGGTATGCGCTGGCTAACGAGGTCAGCCTGCCGGAAGAG
+AGCTTTTATCGCCCGGCGATTAAAGCGAAATGTCGCGATGGCTTTTGCCCGCTGGGTGAA
+ATGGCGCCGCTGAGTGATGTGGATAATCTCACCATTATCACTGAAATCAACGGACGAGAA
+GCGGACCACTGGAATACTGCCGATTTACAGCGTAGCGCCGCACAACTGCTTAGCGCGTTA
+AGTGAGTTCGCTACACTTAACCCTGGCGATGCGATCTTACTTGGTACGCCGCAGAATCGC
+GTTGCGCTGCGTCCCGGCGATCGGGTGCGTATTCTGGCGAAAGGTTTACCCGCGCTGGAA
+AATCCGGTTGTCGCAGAAGATGAATTCGCCCGCCACCAGACGTTTACGTGGCCGCTGTCA
+GCGACGGGAACGTTATTTGCGCTGGGGTTGAACTACGCCGATCACGCCAGCGAGCTGGCA
+TTTACGCCGCCGAAAGAGCCGCTGGTATTTATCAAAGCGCCAAACACCTTTACCGAACAT
+CACCAAACGTCGGTGCGCCCGAACAACGTCGAATATATGCACTACGAAGCCGAGCTGGTC
+GTGGTGATTGGCAAAACGGCGCGTAAGGTGAGCGAAGCCGAAGCCATGGAGTATGTGGCC
+GGTTACACCGTCTGTAACGACTACGCGATCCGCGACTATCTGGAAAACTACTACCGTCCG
+AATCTGCGGGTAAAAAGCCGCGACGGCCTGACGCCGATAGGCCCGTGGATTGTGGATAAA
+GAGGCGGTTTCTGATCCGCACAACCTGACGTTACGCACCTTTGTCAACGGTGAGCTGCGG
+CAGGAAGGGACGACCGCCGATCTGATCTTCAGCATCCCGTTCCTGATTTCTTATCTGAGC
+GAATTTATGACGTTGCAACCGGGCGACATGATTGCCACCGGTACGCCGAAAGGGCTGTCC
+GATGTGGTGCCGGGGGATGAAGTTGTCGTTGAAGTAGAAGGCGTGGGTCGCCTGGTTAAC
+CGAATCGTCAGTGAGGAGAGCGCAAAATGA
+>11111_1#11_04068
+ATGAAGAAAATAAATCATTGGATTAACGGCAAAAACGTTGCAGGTAACGACTACTTCCAG
+ACCACTAACCCGGCGACCGGTGATGTGCTGGCGGAAGTAGCCTCCGGCGGTGAAGCAGAA
+GTGAACCAGGCTGTCGCGGCGGCAAAAGAGGCGTTCCCGAAATGGGCCAACCTGCCGATG
+AAAGAGCGCGCGCGCCTGATGCGCCGCCTTGGCGACCTGATTGACCAGCATGTGCCGGAA
+ATCGCGGCGATGGAAACCGCCGACACCGGCCTGCCTATTCACCAGACTAAAACGTGCTGA
+>11111_1#11_04069
+GTGCTGATCCCGCGCGCCTCGCATAACTTCGAATTCTTCGCCGAAGTGTGCCAGCAGATG
+AACGGCAAGACCTATCCGGTTGACGATAAAATGCTCAATTATACGCTGGTGCAGCCCGTC
+GGCGTCTGCGCGCTGGTGTCGCCGTGGAACGTGCCGTTTATGACCGCGACTTGGAAAGTT
+GCGCCGTGCCTGGCGCTGGGTAACACCGCGGTGCTCAAAATGTCCGAGCTGTCGCCGCTG
+ACTGCCGACAGGCTGGGCGAGCTGGCACTGGAGGCAGGAATTCCGGCAGGCGTGCTGAAC
+GTGGTGCAGGGCTACGGCGCGACGGCGGGCGATGCGCTGGTACGCCACCATGACGTGCGT
+GCGGTGTCGTTTACCGGCGGTACCGCCACCGGTCGCAATATCATGAAAAATGCCGGGCTG
+AAAAAATACTCGATGGAGCTGGGCGGCAAATCGCCGGTGCTGATTTTTGAAGACGCCGAC
+ATTGAGCGCGCGCTGGACGCCGCGCTGTTCACCATCTTCTCGATCAACGGCGAACGCTGC
+ACCGCTGGGTCGCGCATCTTTATCCAGCAGAGCATTTACCCTGAGTTCGTGAAGCGCTTT
+GCCGAACGCGCGAATCGCCTGCGTGTCGGCGATCCGACCGACCCGAACACCCAGGTCGGC
+GCGCTGATTAGCCAACAGCACTGGGAGAAAGTCTCCGGTTATATCCGCCTCGGCATTGAA
+GAGGGGGCAACGCTGCTGGCGGGCGGTGCGGAAAAACCCACTGACCTGCCTGCGCATCTG
+AAAGGCGGTAACTTCCTGCGCCCAACCGTGCTGGCCGATGTCGACAACCGTATGCGCGTT
+GCGCAGGAAGAGATCTTTGGGCCGGTCGCCTGCCTGCTGCCATTCAAAGACGAAGCGGAA
+GGGTTACGTTTGGCGAACGATGTGGAATACGGTCTGGCCTCTTATATCTGGACCCAGGAC
+GTGAGCAAAGTGTTGCGCCTGGCGCGTGGGATTGAAGCCGGCATGGTCTTCGTCAACACC
+CAGAACGTCCGCGACCTGCGCCAGCCGTTCGGCGGCGTGAAAGCCTCCGGTACCGGGCGC
+GAAGGCGGCGAATATAGCTTCGAAGTGTTTGCGGAAATGAAAAACGTCTGCATCTCAATG
+GGCGACCATCCTATCCCAAAATGGGGAGTTTGA
+>11111_1#11_04070
+ATGGGCAAGTTAGCGTTAGCAGCAAAAATTACCCACGTGCCGTCGATGTATCTTTCTGAA
+CTGCCAGGAAAAAATCACGGTTGTCGTCAGGCAGCCATTGATGGGCATATTGAAATTGGC
+AAGCGTTGCCGCGAAATGGGCGTTGACACCATTATCGTATTCGACACCCACTGGCTGGTG
+AATAGCGCTTACCACATTAATTGTGCCGACCATTTCCAGGGCGTCTATACCAGCAACGAA
+TTGCCGCACTTTATTCGCGACATGACCTATGACTATGACGGTAATCCGGCGCTCGGCCAT
+CTGATCGCCGACGAGGCGGTCAAACTGGGCGTGCGCGCCAAAGCGCACAACATCCCGAGC
+CTGAAGCTGGAGTATGGCACGCTGGTGCCGATGCGCTACATGAACAGCGACAAGCACTTC
+AAAGTGGTCTCCATCTCGGCGTTCTGCACTGTGCATGATTTTGCCGACAGCCGCAAACTG
+GGCGAAGCCATTCTCAAGGCGATTGAGAAATATGACGGTACCGTAGCGGTATTCGCCAGT
+GGTTCTCTGTCGCACCGTTTTATTGACGACCAACGGGCGGAAGAGGGGATGAACAGCTAC
+ACCCGCGAGTTCGATCATCAAATGGACGAGCGCGTGGTCAAGCTGTGGCGCGAAGGCAAA
+TTCAAGGAGTTTTGCACCATGTTGCCGGAGTACGCCGACTACTGCTACGGCGAAGGCAAC
+ATGCACGACACGGTCATGCTACTGGGAATGCTGGGGTGGGACAAATACGACGGCAAGGTG
+GAGTTCATCACCGACCTGTTCGCCAGCTCCGGTACCGGCCAGGTAAACGCTGTTTTCCCG
+CTGCCTGCGTAA
+>11111_1#11_04071
+ATGCCGCACTTTATTGCTGAATGTACTGAAAATATTCGCGAGCAGGCTGATTTACCAAGC
+CTGTTCAGCAAGGTAAACGAGGCGCTGGCCGCCACCGGGATTTTCCCCATCGGCGGTATC
+CGCAGTCGCGCCCACTGGCTGGATACCTGGCAGATGGCTGACGGTAAGCATGATTACGCG
+TTTGTGCATATGACGCTGAAAATCGGCGCCGGGCGCAGCCTGGAGAGCCGTCAGGAAGTC
+GGCGAAATGCTGTTTGGGCTGATTAAAGCCCACTTCGCCGACCTGATGGAGAACCGCTAT
+CTGGCGCTGTCGTTTGAGATTGCCGAGTTACATCCAACGCTCAATTACAAACAAAACAAC
+GTACACGCGTTATTTAAATAG
+>11111_1#11_04072
+ATGCTCGATAAACAGACCCATACCCTGATCGCTCAGCGACTTAATCAGGCTGAAAAACAG
+CGTGAACAGATTCGCGCAGTGTCGCTGGATTATCCCAACATCACTATTGAAGATGCCTAT
+GCCGTACAGCGTGAATGGGTCAATATCAAGATTGCCGAAGGGCGCACGCTCAAAGGCCAC
+AAAATCGGCCTGACCTCAAAAGCGATGCAGGCCAGCTCGCAAATCAGCGAACCGGATTAC
+GGCGCGCTGCTTGACGATATGTTCTTCCATGACGGCGGAGATATCCCCACCGACCGTTTT
+ATCGTCCCGCGTATTGAAGTGGAGCTGGCGTTCGTGCTGGCGAAACCGCTGCGCGGCCCT
+CACTGCACGCTGTTCGACGTCTACAACGCCACGGATTATGTGATTCCGGCGCTGGAACTG
+ATTGACGCCCGCAGCCACAACATCGACCCGGAAACCCAGCGCCCGCGCAAAGTGTTCGAC
+ACCATTTCCGACAACGCCGCCAACGCCGGGGTGATCCTCGGTGGTCGCCCCATCAAACCA
+GACGAGCTGGATCTGCGCTGGATCTCCGCGCTGCTCTATCGCAACGGCGTGATCGAAGAA
+ACCGGCGTCGCCGCAGGCGTGCTGAATCATCCGGCCAACGGCGTGGCGTGGCTGGCGAAC
+AAGCTTGCCCCCTACGATGTCCAGCTTGAAGCCGGGCAGATCATCCTCGGCGGCTCGTTC
+ACCCGCCCGGTGCCGGCGCGCAAGGGCGACACCTTCCATGTCGATTACGGCAACATGGGC
+GCGATCAGTTGCCGGTTTGTGTAA
+>11111_1#11_04073
+ATGAAAAATGCTTTCAAAGACGCGTTAAAAGCGGGGCGCCCGCAAATCGGTTTGTGGCTG
+GGGCTTGCCAACAGTTACAGCGCTGAACTGTTAGCGGGCGCCGGCTTCGACTGGCTACTG
+ATTGACGGTGAACACGCGCCAAACAACGTGCAGACGGTGTTGACCCAGTTGCAGGCGATT
+GCGCCTTATCCCAGCCAGCCGGTGGTGCGTCCGTCATGGAACGATCCGGTACAGATTAAG
+CAACTGCTCGACGTCGGCGCGCAAACGCTGCTGATACCGATGGTGCAGAATGCCGATGAA
+GCGCGAAACGCCGTGGCGGCTACGCGTTATCCGCCTGCCGGTATTCGCGGCGTGGGCAGC
+GCGCTGGCGCGGGCATCGCGCTGGAATCGCATTCCGGACTATCTCCACCAGGCCAACGAC
+GCCATGTGCGTACTGGTGCAGATTGAAACGCGTGAGGCGATGAGCAATCTGGCGTCAATT
+CTCGACGTGGATGGCATTGACGGCGTGTTTATTGGCCCGGCGGATCTCAGCGCCGATATG
+GGCTTTGCCGGCAATCCGCAGCACCCGGAAGTGCAGGCGGCGATTGAGAACGCCATCGTG
+CAGATACGCGCGGCGGGGAAAGCGCCGGGGATTCTGATGGCCAATGAAGCACTGGCGAAA
+CGTTATCTGGAACTGGGGGCGCTATTTGTCGCCGTCGGCGTTGACACCACGCTGCTGGCG
+CGCGGAGCGGAGGCGCTGGCGGCGCGCTTTGGCGCAGAAAAAAAACTGTCCGGTGCGTCC
+GGCGTCTATTAA
+>11111_1#11_04074
+ATGAGCGACACATCATCTGCACTTCCGGAAAGCCCCGAGTCTGTCGGTTCGCACAACGCG
+CTCAGCACGGGTCAACAAACCGTCATAAATAAACTGTTCCGCCGACTGATCGTATTTTTA
+TTCGTGTTGTTTATCTTCTCGTTTTTAGACCGTATCAACATCGGTTTTGCCGGGTTGACG
+ATGGGGCAGGATCTGGGGTTAAGCGCCACCATGTTTGGTCTTGCCACGACGCTGTTTTAC
+GCCACCTACGTCATTTTCGGCATTCCCAGCAACGTGATGTTGAGCATCGTCGGCGCCCGC
+CGCTGGATTGCGACCATTATGGTGCTATGGGGCATTGCATCTACCGCCACGATGTTCGCG
+GTGGGACCGAAAAGCCTGTATGTGCTGCGAATGCTGGTGGGCATTACCGAAGCGGGCTTT
+TTGCCAGGAATATTGCTCTATTTAACCTACTGGTTCCCGGCATTTTTCCGCGCCCGCGCC
+AACGCATTATTTATGATTGCCATGCCGGCCACTACCGCGTTGGGGTCAATTGTCTCCGGC
+TATATTTTATCGCTGGACGGCATATTCAATCTGCATGGATGGCAGTGGTTATTCCTGTTG
+GAAGGATTTCCGTCAGTTTTGTTAGGCATTATGGTCTGGTTTTACCTGGATGATACCCCG
+GCAAAAGCCAAATGGCTGACGGCAGAGGATAAAAAATGTTTGCAGGAGATGATGGATAAT
+GATCGCCTGACGCTGGTTCAGCCTGAGGGGGCCATCAGCCATAACGCCATGCAGCAGCGT
+AGCCTGTGGCGCGAAGTATTCACGCCAATTGTACTGATGTATACGCTGGCCTATTTTTGC
+CTTACCAATACGCTTAGCGCCATTAGTATCTGGACGCCGCAAATCCTGAAAAGTTTTAAT
+GAAGGCAGCAGCAATATCACCATCGGCCTGCTGGCGGCGATCCCGCAGATTTGTACTGTT
+CTGGGCATGATTTACTGGAGCCGCCATTCGGACAAACATCAGGAGCGTAAACACCACACT
+GCGTTACCGTTCCTGTTTGCCGCCGCGGGCTGGCTGCTGGCGTCGGCGACCGACCGTAAC
+CTGATCCAGCTCCTGGGGATCGTGATGGCATCCACGGGTTCCTTTAGCGCGATGGCGATC
+TTCTGGACCACGCCGGATCAGTCGATCAGTTTACGCGCCAGGGCGATAGGCATTGCGGTC
+ATCAATGCCACCGGCAATATTGGCTCCGCGCTCAGCCCGGTTATGATTGGCTGGCTAAAA
+GATATCACTGGTAGCTTCAATAGCGGACTCTGGTTTGTCGCTTCTCTGTTAGTCGTCGGC
+GCCGCCATTATCTGGCTCATTCCCATGAAAGCATCGCGTCCGCGCGCCACCCCTTGA
+>11111_1#11_04075
+ATGTGCCAACGTGCGATCGCCAATATTGATATCAGCAAAGAGTATGACGAAAGCATGGGC
+AGTAACGATGTGCATTATCAGTCGTTTGCTCGTATGGCGGATTTCTTTGGTCGTGATATG
+CAGGCGCATCGCCACGACCAGTTTTTTCAAATGCACTTTCTTGATACCGGGCAGATTGAG
+CTACAGCTCGACGATCATCGCTATTCGGTGCAGGCGCCGCTATTTGTGCTAACGCCGCCC
+TCGGTGCCGCATGCTTTTATTACCGAATCGGATAGCGATGGTCATGTTCTGACGGTACGC
+GAAGAGCTGGTTTGGCCGCTGCTGGAAGTGCTTTATCCCGGCACCAGAGAGGCCTTCGGC
+CTGCCGGGAATCTGCCTGTCGCTGGCGGATAAACTCAACGAGCTGGCGGCGCTCAAACAT
+TACTGGCAGCTAATTGAGCGGGAGTCCACGGAACAACTGGCTGGCTGCGAACATACCTTG
+GTACTACTGGCGCAGGCGGTATTTACCTTGCTGTTGCGTAATGCGAAGCTGGACGATCAT
+GCCGCAACCGGGATGCGCGGTGAACTGAAACTTTTTCAGCGCTTTACCCTGTTAATTGAC
+AACCACTTCCATCAGCACTGGACGGTGCCCGATTATGCCTGTGAGTTGCATATTACCGAA
+TCTCGTTTGACCGATATTTGCCGACGTTTTGCTAATCGCCCGCCTAAACGCCTGATTTTT
+GATCGGCAATTACGCGAGGCGAAACGACTGCTGCTTTTTTCCGACAATGCTGTCAACGAG
+ATCGCCTGGCAATTAGGTTTTAAAGATCCGGCTTATTTCGCCCGTTTCTTTAATCGCCTT
+GCTGGCTGTTCTCCTTCGCAGTTTCGCCAACGTGAAGTTCCTTCTTTTCTCAACTAA
+>11111_1#11_04076
+ATGATGAAAAAAAGCGTCGCTATGCTGGCGGTTTGTATGCTGGCGCAAAGCCACCTTGCC
+ATTGCTGCCGGTGCTCCTGCGCCTCAAGAGATCAACATTGTTTTACTGGGCACCAAAGGC
+GGGCCTTCTTTGCTCAATACAGCCAGACTACCGCAAGCGACGGCGCTCACTATCGGCGAT
+AAGATATGGCTGATAGATGCCGGCTACGGCGCCAGTCTGCAACTGGTGAAAAATGGCATT
+CCACTGCGCAACATCAATACTATTTTGCTCACCCATCTGCACAGCGACCACATACTGGAT
+TATCCTTCCTTGCTGATGAATGCCTGGGCAAGTGGCCTGAAAGACCATACCATACAGGTT
+TATGGCCCGCCGGGAACCCAGGCGATGACGAAGGCTAGCTGGAAGGTCTTTGACAGGGAT
+ATCACGTTACGCATGGAAGAAGAGGGGAAACCCGATCCGCGCAACCTGGTTAAGGCGACC
+GATATCGGCCAGGGCGTCATCTATAAAGATGAACTGGTCACAATAAGCGCGCTGAAAGTG
+CCTCATTCCCCTTTCCCGGACGGTGAAGCGTTTGCTTACCGTTTTGATACTCAGGGTAAG
+CGAATCGTCTTCTCTGGCGATACGTCCTGGTTTCCTCCGCTTGCAACGTTTGCCCAGGGG
+GCGGATATCCTGGTACATGAGGCGGTACATGTCCCTTCGGTAGCAAAACTGGCTAATAGT
+ATTGGCAACGGAAAAACGCTGGCTGAAGCGATTGCGTCGCATCACACCACGATTGAAGAT
+GTCGGTAAGATTGCTCGCGAGGCCCACGTGAAAAAACTGGTGTTAAGTCATCTGGTGCCT
+GCGACGGTTGCGGATGACGTCTGGCAACAGGAAGCCATGAAAAATTACCCGGGCCCTGTC
+ATTGTCGGTCATGACAATATGACGATAAGCGTACCGTAA
+>11111_1#11_04077
+ATGGCTAACATCACTGTCACCTTTACCATCACCGAATTTTGTTTGCACACCGGCGTGACG
+GAAGAGGAGCTAAACGAAATCGTCGGACTTGGCGTAATTGAGCCTTACGAAGACGATAAC
+GCCGACTGGCAATTCGACGATCGCGCAGCGAGCGTGGTACAACGCGCGCTACGCTTACGC
+GAGGAGCTGGCGCTCGACTGGCCAGGGATCGCGGTCGCGTTAACGCTGCTGGAAGAGAAT
+TCACGGCTGCGCGAAGAAAACCGGTTACTGCTGCAACGCCTTTCTCGCTTTATCTCGCAT
+CCCTAA
+>11111_1#11_04078
+ATGGAACTTAAGGATTATTACGCCATTATGGGCGTGAAACCGACGGACGATCTCAAGACG
+ATTAAGACCGCCTATCGCCGACTGGCCCGCAAGTACCATCCAGATGTCAGCAAAGAACCC
+GATGCCGAAGCCCGTTTCAAAGAGGTTGCTGAAGCATGGGAAGTGCTGAGTGATGAGCAA
+CGGCGCGCCGAGTATGACCAGTTATGGCAACACCGTAACGATCCACAATTTAATCGCCAG
+TTCCAGCAACACGAAGGCCAGCCGTATAACGCCGAAGATTTTGATGATATTTTCTCGTCT
+ATTTTTGGTCAGCACGGTCGTCATTCGCACCACCGCCACGCCGCACGCGGTCATGATATC
+GAAATTGAAGTGGCGGTATTCCTGGAAGAAACGCTGGAAGAGCACCAGCGTACGATTAGC
+TATTCCGTCCCCGTTTATAACGCGTTCGGCCTGGTGGAGCGGGAAATTCCCAAAACATTG
+AATGTGAAAATCCCGGCTGGCGTCAGCAACGGGCAACGAATCAGACTGAAAGGCCAGGGC
+ACGCCGGGGGAAAACGGCGGACCTAATGGCGATTTATGGCTCGTTATCCATATTGCCCCG
+CATCCGCTCTTTGATATCGTCAATCAGGATCTGGAAGTCGTCCTTCCGCTTGCCCCATGG
+GAGGCGGCGCTCGGCGCTAAGGTGTCTGTGCCAACGCTTAAAGAGCGTATTTTGCTGACC
+ATTCCCCCCGGCAGCCAGGCAGGTCAGCGGCTGCGTATCAAAGGAAAAGGATTAGCCAGT
+AAAAAGCACACTGGCGATCTCTATGCCATCATCAAAATCGTTATGCCGCCGAAACCTGAC
+GAGAAAACAGCTGCCCTGTGGCAACAACTGGCGGACGCGCAGTCGTCCTTTGACCCACGC
+CAGCAATGGGGGAAAGCATAA
+>11111_1#11_04079
+ATGGCGAAACAACAACGGATGGGCTGGTGGTTTCTTTGCCTTGCATGTGTCGTGGTAATG
+GTTTGTACCGCGCAACGCATGGCGGGCCTGCACGCCTTGCAGATGCAGGCGACGGCCTCT
+GCTGCGGTGGTCAGCGCTCCCTCCTCGACAGATGACGGCTCGCCGGTCACTCCCTGCGAA
+TTAAGCGCCAAGTCGCTGCTGGCGGCGCCTCCAGTACTCTTTGAAGGTGCTATCCTTGCG
+CTTTATCTACTGCTTTCCTTACTGGCGCCTGTCCGGGTCATGCGCCTGCCGTTTTCGCCT
+CCACGGGCTATTTCGCCGCCCACATTACGGGTACATCTACGATTTTGTGTCTTCCGTGAA
+TGA
+>11111_1#11_04080
+ATGATGATTTTATTCAGGCGGATACTGTTCTGCCTGTTATGGCTTTGGCTGCCCGTCTCC
+TGGGCGGCGGAAAGCGGCTGGCTGCGTTCGCCCGATAACGACCATGCCAGCATACGGCTA
+CGTGCCGATACGTCCGCTAACAGTGAGACCCGGCTGTTGCTGGATGTCAAACTGGAAAAC
+GGCTGGAAAACCTACTGGCGCGCGCCGGGGGAAGGGGGCGTGGCACCCTCTATCGCCTGG
+AAAGGCGACATGCCTGAGGTAAGCTGGTTCTGGCCAACCCCCTCGCGCTTTGATGTGGCG
+AATATCACCACCCAGGGATATCACGACGAGGTGACCTTTCCGATGATCGTGCGCGGTACG
+CCGCCGGCGACCTTGCGCGGTGTGTTGACGTTATCAACCTGCAGCAATGTTTGTCTGTTG
+ACCGATTACCCCTTTTCCGTGACGCCCACTGTGCAGAATGCCGATTTTGCCCATGACTAT
+GCGCGGGCGATGGGTAAAGTTCCGCTCCGCAGTGGGCTAACGGACTCGCTTGACGTTGGC
+TATCGCCCGGGAGAACTGGTGGTCACTGCTACGCGAGCGGCGGGCTGGTCATCGCCCGGG
+CTCTATCTTGACACCATAGATGACGTCGATTTTGCGAAGCCTCGCCTGCGCGTAGAGGGC
+GACAGGTTACAGGCGACGGTGCCGGTGACGGACAGTTGGGGCGAAAAGGCGCCCGATTTG
+CGCGACAAATCGCTGACCCTCGTGTTAGCCGATGGCGCTATCGCCCAGGAGAGCACGCAA
+ACCATTGGCGCTGCGCCAGCGCAAACGCCGGACAATGCGGCGCTACCTTTCTGGCAAGTT
+GTAATGATGGCGCTAATCGGCGGACTGATTCTTAATTTAATGCCCTGCGTACTGCCTGTT
+CTGGGCATGAAACTTGGCTCTATTTTATTGGTAGAGGAAAAAAGCCGCTCTCACATCAGG
+CGACAATTTTTGGCTTCGGTCGCCGGTATCATTGCGTCATTTATGGCGCTGGCGGCGTTT
+ATGACCCTCCTTCGCCTGTCAAACCATGCGCTGGCCTGGGGAGTCCAGTTCCAGAATGCA
+TGGTTTATTGGTTTTATGGCGCTGGTGATGTTGTTGTTTAGCGCCAGCCTGTTCGGGCTT
+TTTGAGTTCAGGCTTCCCTCATCTATGACCACGAAACTGGCCACTTACGGCGGTAACGGT
+ATGTCGGGACATTTCTGGCAGGGGGCGTTCGCCACGCTGCTGGCGACGCCTTGTAGCGCG
+CCGTTTCTGGGCACGGCGGTCGCGGTGGCGCTCACGGCGTCGCTGCCGACGCTGTGGGGG
+CTGTTCCTTGCGCTTGGCCTGGGAATGAGCGCGCCGTGGCTACTGGTCGCGATACGACCA
+GGGCTTGCGCTACGTTTACCGCGCCCCGGGCGTTGGATGAATGTCCTGCGCAGGATCCTC
+GGTCTGATGATGCTGGGGTCGGCTATCTGGCTGGCGACGTTACTCCTGCCGCATTTCGGC
+TTCACTGCGTCAAAGAGCGCGCAAGACACGGTTCAGTGGCAACCGTTGAGTGAACAGGCA
+ATCCAGTCGGCGCTGGCGCAGCATAAGCGGGTATTTGTCGATGTCACTGCGGACTGGTGT
+ATTACCTGTAAAGTGAATAAATACAACGTCCTGCAAAAAGAGGATGTGCAGGCCGCCTTG
+CAACAGCCGGATGTTGTGGCGCTGCGGGGAGACTGGACGCTGCCGTCCGATGCCATTACA
+GATTTTCTGAAAACGCGCGGCCAGGTCGCCGTGCCGTTTAATCAGGTATATGGCCCCGGT
+TTGCCGGAAGGGGAGGCACTGCCCACTTTGCTGACCCGCGATGCGGTATTACAAACGTTG
+AAAAAAGCGAAAGGAATAACCCAATGA
+>11111_1#11_04081
+ATGAAATACATGATTGTTTTACTGCTGGCGCTGTTTTCGACGCTGAGCATCGCGCAAGAA
+ACCGCTCCTTTTACGCCGGATCAGGAAAAGCAGATTAAAAATCTGATCCATGCGGCGTTG
+TTTAACGATCCTGCCAGCCCGCGGATAGGCGCTAAACACCCTAAGCTGACGCTGGTGAAC
+TTTACGGATTACAACTGCCCGTACTGCAAACAGCTCGATCCGATGCTGGAAAAGATTGTG
+CAGAAATATCCTGACGTTGCGGTCATTATTAAACCGCTGCCATTCAAAGGAGAGAGTTCC
+ATACTGGCGGCGCGTATTGCGCTGACCACCTGGCGCGATCATCCGCAACAGTTCCTCGCG
+CTACATGAAAAACTTATGCAAAAGCGCGGTTACCATACGGATGACAGTATTAAACAGGCC
+CAGCAGAAAGCAGGGGCGACGCCAGTGACGCTGGATGAAAAAAGCATGGAAACGATACGC
+ACTAATTTGCAGTTGGCAAGACTGGTCGACGTGCAAGGAACGCCAGCGACGATCATTGGC
+GACGAGCTGATTCCGGGCGCAGTGCCCTGGGATACGCTGGAAGCGGTGGTGAAAGAAAAA
+CTGGCGGCTGCCAATGGCGGGTAA
+>11111_1#11_04082
+ATGGCGGGTAAACTGCGGCGTTGGCTGCGTGAAGCCGCGGTTTTTCTGGCGCTCCTCATC
+GCGATAATGGTGGTCATGGACGTCTGGCGCGCGCCGCAGGCGCCTCCGGCGTTTGCCGCG
+ACACCATTACATACGCTGACGGGAGAGTCGACAACTCTGGCGACCTTGAGCGAGGAACGC
+CCCGTACTGCTCTATTTTTGGGCCAGCTGGTGCGGGGTATGCCGCTTTACCACGCCTGCG
+GTCGCTCACCTGGCGGCGGAAGGGGAAAACGTCATGACCGTTGCGCTCCGCTCCGGCGGT
+GATGCTGAGGTTGCCCGCTGGCTGGCGCGCAAGGGCGTTGACTTCCCGGTCGTCAATGAT
+GCTAACGGCGCCTTATCCGCTGGCTGGGAAATCAGCGTGACGCCAACGCTGGTGGTGGTT
+TCACAAGGTCGGGTTGTGTTCACCACCAGCGGCTGGACCAGCTATTGGGGCATGAAGCTT
+CGGCTGTGGTGGGCAAAAACGTTCTGA
+>11111_1#11_04083
+ATGAAAAAATCATTACTCGCTGTTGCTGTGGCAGGGGCTGTTTTGTTGTCATCCGCCGTA
+CAGGCGCAGACAACGCCGGAAGGTTATCAATTACAACAGGTGCTGATGATGAGCCGCCAT
+AATCTGCGGGCGCCGCTGGCGAATAATGGCAACGTACTGGCGCAGTCGACGCCGAACGCC
+TGGCCGGCGTGGGACGTTCCCGGCGGGCAACTGACGACGAAAGGCGGCGTGCTGGAAGTC
+TATATGGGACACTACACACGTGAATGGCTGGTCGCGCAGGGGCTGATACCGTCGGGAGAA
+TGTCCGGCGCCCGACACGGTATATGCCTATGCGAATAGTTTGCAGCGCACCGTCGCCACC
+GCGCAATTTTTCATTACCAGCGCTTTCCCCGGCTGTGATATTCCTGTTCATCATCAGGAA
+AAAATGGGCACTATGGACCCTACCTTCAATCCGGTGATTACCGATGATTCCGCCGCGTTC
+CGGCAACAGGCCGTACAGGCGATGGAAAAGGCGCGTAGTCAGCTACATCTTGATGAGAGT
+TATAAACTGCTTGAGCAGATAACGCATTATCAGGACTCGCCGTCCTGCAAAGAGAAGCAT
+CAGTGTTCGCTAATCGACGCGAAAGATACCTTCAGCGCGAACTATCAGCAAGAGCCTGGC
+GTGCAGGGGCCGCTGAAAGTAGGGAACTCGCTGGTGGATGCGTTTACCCTGCAATATTAC
+GAAGGCTTTCCGATGGATCAGGTCGCTTGGGGCGGGATCCACACCGATCGGCAGTGGAAG
+GTGCTGTCAAAACTGAAAAACGGCTACCAGGACAGCCTGTTTACCTCACCCACGGTGGCG
+CGCAATGTCGCTGCGCCGCTGGTAAAATATATCGATAAGGTGCTGGTTGCCGAGCGCGTT
+AGCGCGCCGAAGGTTACCGTGCTGGTGGGGCATGATTCCAATATCGCGTCGCTGCTGACG
+GCGCTGGATTTTAAACCCTATCAGCTCCATGACCAGTATGAGAGAACGCCGATTGGTGGT
+CAGCTTGTCTTCCAACGCTGGCATGACGGTAACGCTAACCGGGATTTGATGAAAATCGAG
+TATGTCTACCAGAGCGCCCGGCAGTTACGTAATGCGGAAGCGTTAACGCTCAAATCGCCT
+GCGCAAAGGGTAACGCTGGAACTGAAAGGATGTCCGGTGGATGCGAACGGCTTCTGTCCG
+CTGGATAAGTTCGATAACGTCATGAACACTGCTGCAAAATAG
+>11111_1#11_04084
+ATGCCAACTCAAGAAGCAAAAGCGCACCGCGTCGGCGAATGGGCAAGCCTGCGTAATACG
+TCGCCGGAAATTGCCGAAGCCATTTTTGAAGTCGCTCACTATGACGAGAAACTGGCAGAA
+AAAATATGGGAAGAAGGTAGCGATGAGGTGCTGATCAAAGCCTTTGAGAAAACGGACAAA
+GACTCGCTCTTCTGGGGCGAACAAGTCATCGAACGTAAGAACGTATAA
+>11111_1#11_04085
+ATGGCAAAGATTCTGGTGCTCTATTATTCCATGTACGGACACATTGAAACCATGGCGCAC
+GCGGTGGCGGAAGGGGCAAAGAAAGTCGACGGCGCAGAGGTCATTATAAAGCGTGTGCCA
+GAAACAATGCCGCCTGAAATCTTCGCAAAAGCTGGCGGTAAAACGCAAAACGCACCGGTT
+GCCACCCCACAGGAGCTGGCGGATTACGATGCCATTATTTTTGGTACGCCAACCCGGTTT
+GGCAATATGTCAGGCCAGATGCGTACCTTCCTGGACCAAACCGGCGGACTGTGGGCATCC
+GGCGCGCTATACGGCAAGCTCGGCGGCGTGTTCAGTTCTACCGGAACGGGCGGCGGCCAG
+GAGCAGACCATCACCTCGACCTGGACTACGCTTGCCCATCATGGGATGGTGATTGTCCCG
+ATAGGCTATTCCGCACAGGAACTGTTTGACGTCTCCCAGGTTCGCGGCGGTACGCCTTAC
+GGCGCAACGACTATCGCTGGAGGCGACGGTTCACGTCAACCAAGCCAGGAGGAACTCTCT
+ATCGCTCGCTATCAGGGGGAATACGTCGCCGGTCTGGCAGTCAAACTCAACGGCTAA
+>11111_1#11_04086
+ATGGCAAACCATCGTGGCGGTTCCGGTAATTTTGCGGAAGACCGCGAAAGAGCATCAGAA
+GCAGGTCGTAAAAGTGGTCAGCACAGCGGGGGCAATTTTAAGAATGACCCGCAGCGTGCA
+TCCGAAGCAGGCAAAAAAGGGGGCAAAAGCAGTAACCGTAATCGCTAG
+>11111_1#11_04087
+ATGTCGCAACGCACAGAGAAAAAAATCGGGAAACGTTCGCAGGCCACCGGTGCAAAACGG
+CAGCTTATCTTAACCGCCGCGCTTGCCGTTTTTTCCCAGTATGGCATTCATGGCGCGCGT
+CTTGAACAGGTCGCCGAGCGGGCAGGCGTCTCCAAAACCAATCTGCTTTATTATTATCCC
+TCGAAAGAGGCGCTGTATGTCGCGGTAATGCGACAGATTCTGGATGTCTGGTTGGCGCCG
+CTCAAGGCGTTTCGCGCAGAATTTTCCCCTCTGGAGGCCATCAAAGAGTATATCCGTCTC
+AAGCTGGAGGTTTCGCGTGATTATCCGCAGGCGTCGCGGCTCTTCTGCATGGAGATGCTG
+GCGGGCGCGCCGCTCTTAATGGATGAACTGACCGGCGATCTAAAAGCGTTGATAGATGAA
+AAATCCGCGCTGATTGCCGGATGGGTGCACAGCGGGAAACTCGCGCCCGTTTCTCCGCAT
+CATTTGATCTTCATGATTTGGGCCGCCACGCAACATTACGCCGATTTCGCCCCTCAGGTT
+GAAGCGGTAACCGGCGCGACGCTTCGCGATGAAGCCTTTTTCAACCAAACGGTCGAAAGC
+GTTCAGCGCATTATTATTGAAGGGATTCGCGTGCGTTAA
+>11111_1#11_04088
+ATGAAACGAATTTTCCTTACCTGCGCGGCGTTGTTGTTCAGCAGTCAGGCGTTGGCCGAT
+GAGTGTGCCAGCGCCAGTACGCAGCTGGAAATGAATCGCTGCGCCGCCGCGCAATACCAG
+GCGGCAGATAAAAAGCTGAACGAAACCTATCAAAGCGCGATTAAGCGTGCGCAACCGCCG
+CAGCGTGAGCTATTGCAAAAAGCGCAGGTGGCATGGATTGCCCTGCGCGACGCCGATTGC
+GCGCTGATTCGCTCAGGTACGGAGGGCGGCAGCGTTCAACCCATGATCGCCAGCCAGTGC
+CTGACCGATAAAACGAACGAACGCGAAGCGTTTTTAGCCTCGCTGCTGCAATGTGAAGAG
+GGTGATTTGAGCTGCCCACTGCCGCCAGCCGGTTAA
+>11111_1#11_04089
+ATGGGAACCACCACGATGGGGGTTAAGCTGGACGACGCCACGCGCGAACGGATCAAAATG
+GCCGCGTCGCGTATCGATCGCACGCCGCACTGGTTAATAAAACAGGCAATCTTTAGCTAT
+CTGGACAAGCTGGAAAATAGCGATACGCTACCGGAGCTACCTGCGCTGTTTGCCGGCGCG
+GCAAATGAAAGCGAGGAGCCGGTCGCGCCGCAGGATGAGCCGCATCAGCCCTTTCTGGAG
+TTTGCCGAACAGATTCTTCCCCAATCCGTCTCTCGCGCCGCCATCACCGCCGCCTGGCGC
+CGCCCGGAAACCGATGCGGTGTCAATGCTAATGGAACAGGCGCGCCTGTCGCCGCCTGTC
+GCTGAGCAGGCGCATAAACTGGCGTATCAACTGGCGGAGAAATTGCGCAATCAAAAATCC
+GCCAGCGGTCGCGCGGGTATGGTGCAAGGCCTGTTGCAGGAGTTTTCCCTCTCTTCGCAA
+GAAGGCGTAGCGCTGATGTGTCTGGCGGAAGCGCTGCTGCGTATTCCCGACAAAGCTACG
+CGCGATGCGTTAATTCGCGACAAAATCAGTAATGGCAACTGGCAGTCGCATATTGGCCGT
+AGCCCGTCGCTGTTTGTAAACGCCGCCACCTGGGGGCTGCTCTTTACCGGCCGACTGGTC
+TCAACGCATAACGAAGCCAATCTTTCGCGCTCGCTGAACCGCATTATCGGCAAGAGCGGC
+GAACCGTTAATCCGCAAAGGCGTCGACATGGCGATGCGTTTAATGGGCGAGCAGTTCGTG
+ACTGGCGAAACCATTGCTCAGGCGCTGGCGAATGCCCGAAAACTGGAAGAGAAAGGGTTC
+CGCTATTCTTACGATATGCTGGGCGAAGCCGCGTTAACCGCCGCCGATGCGCAGGCCTAT
+ATGGTCTCTTACCAGCAAGCGATTCATGCCATCGGCAAAGCGTCTAACGGTCGCGGTATT
+TACGAAGGGCCAGGCATCTCGATTAAGCTGTCCGCCCTGCATCCACGCTATAGTCGCGCG
+CAATACGATCGGGTAATGGAGGAGCTTTATCCGCGCCTGAAATCCCTGACGCTGCTGGCG
+CGCCAGTATGATATCGGTCTCAATATCGACGCCGAAGAGGCGGATCGTCTGGAGATCTCG
+CTTGATCTGCTGGAAAAACTCTGCTTCGAACCCGAACTGGCGGGCTGGAACGGCATTGGC
+TTTGTGATTCAGGCTTACCAGAAACGCTGCCCGCTGGTCATTGATTATTTAGTCGATCTG
+GCCTCCCGTAGCCGCCGTCGGCTGATGATTCGTCTGGTGAAAGGCGCCTACTGGGATAGC
+GAGATCAAACGCGCGCAAATGGAAGGGCTGGAGGGCTATCCAGTTTATACCCGCAAAGTG
+TATACCGATGTCTCTTATCTGGCCTGCGCGAAAAAACTGCTCGCCGTCCCTAATCTGATC
+TACCCGCAGTTCGCGACCCATAACGCTCACACACTGGCGGCGATTTATCATCTGGCCGGG
+CAAAATTACTATCCGGGTCAGTACGAATTCCAGTGCCTGCACGGCATGGGAGAACCGCTG
+TATGAACAGGTCACCGGTAAAGTGGGGGACGGAAAACTTAACCGTCCCTGCCGTATTTAC
+GCGCCGGTGGGAACACACGAAACCCTGCTGGCCTATCTGGTACGACGCCTGCTGGAAAAC
+GGCGCCAACACCTCTTTTGTCAACCGCATCGCCGATGCCACCCTACCGCTCGATGAACTG
+GTGGCCGACCCGGTCGAGGCCGTGGAAAAACTGGCGCAGCAGGAAGGTCAGGCTGGCATA
+CCGCATCCAAAAATTCCGCTGCCGCGCGATCTGTACGGCGAAGGTCGGATAAACTCCGCC
+GGACTTGATTTAGCGAATGAACATCGCCTCGCCTCGCTTTCTTCTGCCCTGTTAAGCAAC
+GCCATGCAGAAATGGCAGGCCAAACCTGTGCTGGAACAACCGGTGGCCGACGGTGAGATG
+ACGCCGGTTATCAACCCGGCGGAACCGAAAGATATTGTTGGCTGGGGACGCGAAGCGACA
+GAAAGCGAGGTTGAACAGGCGTTGCAAAACGCGGTCAATCAGGCGCCGGTTTGGTTTGCG
+ACGCCGCCGCAAGAACGCGCCGCTATTTTGCAGCGGGCGGCGGTATTGATGGAAGACCAA
+ATGCAGCAGTTGATTGGCCTGTTGGTGCGTGAAGCGGGGAAAACGTTCAGCAACGCCATT
+GCCGAAGTGCGCGAAGCGGTAGACTTCCTCCATTATTATGCCGGTCAAGTGCGTGACGAT
+TTCGATAACGAAACGCATCGCCCGTTAGGGCCGGTGGTCTGTATCAGTCCGTGGAACTTT
+CCGCTGGCCATTTTCACTGGCCAAATCGCCGCCGCGCTGGCGGCAGGTAACAGCGTTCTG
+GCGAAACCGGCAGAGCAGACATCGCTGATTGCCGCCCAGGGCATTGCCATTTTGCTGGAA
+GCGGGCGTACCGCCGGGCGTCGTGCAACTGTTGCCGGGACGGGGAGAAACCGTCGGCGCC
+CAGCTTACCGCCGATGCGCGTGTACGCGGCGTGATGTTTACCGGTTCCACGGAGGTCGCG
+ACGTTGTTGCAGCGCAACATCGCCACGCGTCTTGACGCCCAGGGGCGCCCTATTCCGTTG
+ATTGCGGAAACCGGCGGTATGAACGCTATGATTGTCGACTCTTCCGCGCTCACCGAGCAG
+GTGGTCGTGGATGTGCTGGCTTCCGCCTTCGACAGCGCCGGACAACGCTGTTCCGCGCTC
+CGCGTGCTGTGTTTGCAGGACGATATCGCCGAACATACGCTGAAAATGTTACGCGGCGCG
+ATGGCGGAGTGTCGGATGGGGAATCCAGGCCGTCTGACGACCGATATCGGGCCGGTGATC
+GATAGCGAGGCCAAAGCCAACATTGAACGTCATATCCAGACGATGCGCGCCAAAGGCCGC
+CCGGTTTTCCAGGCCGCGCGTGAAAACAGCGATGACGCGCAGGAATGGCAGACCGGTACG
+TTTGTTATGCCCACGCTTATTGAGCTGGAAAACTTCGCAGAACTGGAAAAAGAGGTCTTC
+GGGCCCGTGCTGCACGTCGTGCGTTATAACCGTAACCAACTGGCGGAGCTTATCGAACAG
+ATTAACGCTTCCGGCTACGGGCTAACGCTGGGCGTACATACCCGTATTGATGAAACCATT
+GCGCAAGTCACCGGTTCCGCCCATGTCGGCAACCTGTACGTTAACCGTAATATGGTGGGC
+GCGGTCGTCGGCGTCCAGCCGTTTGGCGGCGAAGGCCTGTCCGGCACCGGGCCAAAAGCG
+GGAGGGCCGCTCTATCTCTACCGCCTGCTGGCACACCGCCCGCCCAATGCGCTCAATACG
+ACGCTGACTCGTCAGGATGCGCGTTACCCGGTGGATGCGCAGCTTAAAACCACGCTACTC
+GCGCCGTTGACCGCTCTGACGCAATGGGCGGCGGATCGCCCGGCGCTACAGACGCTCTGC
+CGACAATTCGCCGATCTGGCGCAGGCCGGCACGCAGCGCCTGCTACCGGGGCCGACCGGC
+GAGCGTAATACCTGGACGCTGTTGCCGCGTGAACGGGTGTTATGCCTGGCTGATGATGAA
+CAGGACGCGTTGACGCAGCTTGCCGCCGTTCTCGCCGTCGGCAGTCAGGCGCTATGGTCA
+GACGACGCCTTCCACCGCGATCTGGCGAAACGTCTCCCCGCCGCCGTCGCGGCGCGTGTC
+CAGTTTGCGAAAGCGGAAACGCTGATGGCGCAGCCGTTTGACGCGGTGATTTTCCACGGC
+GACTCCGACAAGCTGCGAACCGTGTGCGAAGCCGTCGCCGCCCGCGAAGGCGCGATAGTG
+TCGGTACAGGGGTTCGCCCGCGGCGAAAGCAATATGCTGCTGGAACGGCTCTATATTGAA
+CGTTCGCTGAGCGTAAACACTGCCGCCGCTGGCGGTAATGCCAGCCTGATGACAATTGGC
+TAA
+>11111_1#11_04090
+ATGGCTATTAGCACACCGATGTTGGTGACATTCTGTGTCTATATTTTTGGCATGATATTG
+ATTGGGTTTATCGCCTGGCGCTCAACCAAAAACTTTGATGACTATATTCTTGGCGGTCGC
+AGCCTGGGGCCGTTTGTTACGGCTTTATCAGCCGGCGCGTCGGATATGAGCGGCTGGCTG
+TTAATGGGGCTGCCTGGCGCTATCTTTCTGTCGGGGATCTCTGAAAGCTGGATCGCCATT
+GGCCTGACGTTAGGCGCATGGATTAACTGGAAGCTGGTGGCCGGGCGCCTGCGCGTGCAT
+ACCGAATTTAACAATAACGCGCTCACGCTGCCGGACTATTTTACCGGTCGGTTTGAGGAT
+AAGAGCCGAGTCCTGCGTATTATTTCCGCGCTGGTCATTCTGCTGTTTTTCACTATCTAT
+TGCGCATCAGGTATTGTCGCTGGGGCACGACTGTTCGAAAGCACCTTCGGTATGAGCTAT
+GAAACCGCACTGTGGGCGGGGGCCGCGGCAACCATTATTTATACCTTTATCGGCGGGTTT
+CTTGCCGTTAGCTGGACGGATACCGTTCAGGCCAGCCTGATGATTTTTGCGTTAATCCTG
+ACGCCGGTGATGGTTATTGTCGGCGTAGGCGGTTTTAGCGAGTCGCTGGAAGTGATCAAG
+CAAAAGAGCATCGAGAATGTCGACATGCTCAAGGGGCTGAATTTTGTCGCTATTATTTCT
+CTGATGGGCTGGGGGCTGGGTTACTTCGGTCAGCCGCATATCCTGGCGCGCTTTATGGCG
+GCGGATTCCCATCACAGTATTGTTCATGCGCGTCGTATCAGTATGACCTGGATGATTCTG
+TGTCTGGCGGGCGCGGTGGCGGTGGGCTTCTTTGGCATTGCGTACTTTAACAATAACCCC
+GCGCTGGCCGGGGCGGTGAACCAAAACTCAGAACGCGTATTTATTGAACTGGCGCAGATC
+CTGTTTAACCCGTGGATTGCCGGTGTTCTGCTGTCTGCTATCCTGGCGGCGGTGATGTCG
+ACGTTGAGCTGTCAGTTGCTGGTATGCTCCAGCGCGATTACGGAAGATTTATATAAGGCT
+TTTCTGCGTAAAAGCGCCAGCCAGCAAGAGCTGGTATGGGTAGGGCGAGTGATGGTGCTG
+GTGGTAGCGCTGATCGCCATTGCGCTGGCGGCGAATCCTGATAACCGTGTGCTGGGGCTG
+GTGAGCTACGCCTGGGCTGGATTCGGCGCGGCATTTGGACCTGTTGTCCTGTTTTCTGTG
+ATGTGGTCGCGTATGACACGTAACGGCGCGCTGGCGGGAATGATTATTGGCGCGGTGACG
+GTTATCGTCTGGAAACAATATGGCTGGCTGGATCTGTATGAGATTATCCCTGGCTTCATT
+TTCGGCAGCCTGGGGATCGTAATCTTTAGCCTGCTTGGCAAAGCGCCGACAGCAACGATG
+CAGGAACGCTTTGCAAAAGCGGACGCGCATTATCATTCCGCGCCGCCGTCGAAGCTACAG
+GCGGAATAA
+>11111_1#11_04091
+ATGGTAATGTCCGCACCAGGACACATTGTTTACAGTAGTTACAACACCCTGTACGGACAT
+TCTCTCTCCGGTGGTGGTCTTGTCATCTTAAAAGCTCTCATCATTTCCCTTACTGTCCAT
+ACCCATGACGCCATATGTGGTGCGCGTAGCCGTGTGTGGCGTCGTTTCAAAAAGCAAGCT
+AAGGCTTACAAGGAAGCCAACCCTCAGATGTGTGTGCGCATAATCGCGTTCAAGAGAACG
+CGGGTGATGTATACCTACAACTCAAGGTGCTATCCATGGGAAGACAAAAAGCAGTGA
+>11111_1#11_04092
+ATGGGAAGACAAAAAGCAGTGATCAAAGCTCGTCGTGAAGCAAAGCGTGTGTTGAGACGA
+GATTCGCGTAGTCATAAGCAACGTGAAGAAGAATCGGTCACGTCACTGGTACAGATGGGC
+GGAGTAGAAGCCATTGGCATGGCGCGCGATAGTCGCGATACCTCTCCTGTTAAGGCGCGA
+AATGAAGCACAGGCGCATTATCTGAACGCTATCGACAGTAAACAGCTTATTTTTGCGACC
+GGCGAAGCCGGCTGCGGAAAAACATGGATCAGTGCGGCAAAGGCGGCAGAAGCATTGATT
+CATAAGGACGTCGAGAGGATCATTGTGACGCGTCCGGTATTGCAGGCTGATGAAGATCTT
+GGTTTTTTGCCCGGTGATATCGCTGAAAAATTCGCGCCTTATTTTCGTCCCGTCTACGAT
+GTCCTGCTTAAACGGTTGGGCGCGTCCTTTATGCAATATTGTTTGCGCCCGGAAATCGGT
+AAGGTAGAAATTGCCCCGTTCGCCTATATGCGTGGGCGTACTTTTGAAAATGCGGTCGTG
+ATCCTCGACGAGGCGCAAAATGTGACTGCGGCGCAAATGAAAATGTTTTTGACGCGATTA
+GGCGAAAATGTCACGGTCATTGTCAATGGCGATATTACGCAATGCGACCTGCCGCGCGGT
+GTGCGTTCCGGGTTGAGTGATGCGTTGGAACGCTTTGAAGAAGATGAAATGGTGGGGATT
+GTGCATTTCAACAAAGACGACTGCGTGCGCTCGGCGCTTTGTCAGCGAACGCTCCACGCA
+TACAGCTAA
+>11111_1#11_04093
+ATGGAGCCTCAACCCCCACGTCTTAAACCCGGAAAAATCCTTGACACTCTGGGTGCTATG
+CAAAAAAGCCTGACACGTGCCTCCCAGCGTATTGCGCAATATATTTTAGCCTTCCCCAGA
+CAGGTGACACAGTCATCTATTGCCGATTTGTCGCGCGACACACAGGCCGGAGAAGCCACG
+GTTATTCGCTTTTGTCGCACCCTGGGCTATAAAGGTTTTCAGGATTTTAAAATGGACCTG
+GCCATTGAACTTGCCACTACCGAGTCTGATGACAGTAGTCCTCTACTGGATGCCGAAGTT
+AGCGAATCCGACGATGCCCACGCCATTGGTTTAAAATTGCAGAACACCATTAGTAATGTA
+TTATCTGAAACGCTAAATCTGCTTGATATGCAACAGGTTCTCGGTGTCGTGGACGCCCTA
+CGTCACTGTCACTCAGTTTATATCTTTGGTGTGGGCTCATCGGGGATCACGGCGCTGGAT
+ATGAAACACAAGCTAATGCGTATTGGTTTACGGGGCGATGCGGTAAGCAATAACCATTTT
+ATGTACATGCAGGCTACGCTATTAAAAGCAGGCGATGTCGCGATGGGTGTCAGTCACTCG
+GGCACATCGCCAGAAACAGTGCATTCACTCCGATTGGCCCGACAGGCTGGCGCCACCACA
+GTCGCCATTACCCATAATCTGGGTTCTCCATTATGTGAAGAGGCCGATTTTTGCCTGATC
+AATGGTAATCGGCAAGGAATGTTGCAGGGTGACTCGATCGGTACGAAAGCCGCGCAGCTT
+TTCGTCTTTGACCTGCTCTATACCCTTCTTGTACAGTCCTCGCCGGAACAGGCCCGAGAA
+AGCAAATTACGGACAATGAATGCCCTGGACATGACAAAATAA
+>11111_1#11_04095
+GTGATATGTCTCAAAGTCCAGGGCGGCATTGGTGAAATTTTTACGGTGACGCAGCAGGCG
+GATAAATTCTTTCCGGCTACGCAGTTCCACTGGAGCTGGACGGAAAGCACAGTACCTGTA
+TTGATGATTGGTTTTCTGTTTGCCAATATTCAGCAATTTACTGCCAGTCAGGATGTGGTC
+CAACGCTATATCGTGACTGACTCCATAGAGGAAACGAAGAAAACATTACTTACAAATGCC
+AAACTGGTTGCTGTGATCCCTGTTTTCTTTTTTGCTATCGGCTCGGCATTATTTGTCTAC
+TATCAGCAACATCCACAATTATTACCGGCGGGATTCAACACTGGCGGCATTTTGCCCTTA
+TTCGTGGTCACCGAAATGCCAGTCGGCATTGCAGGGTTGATAATCTCCGCTATTTTCGCT
+GCCGCGCAGTCCAGCATCTCCAGCAGCTTAAACAGCATTTCCAGTTGTTTTAATTCCGAT
+ATCTATCAGCGTTTGAGTCATAAAAAAGGAACGCCAGAAAACCGTATGAAAATAGCTAAG
+TTAGTTATTCTGGTCGCGGGCCTGATAAGTAGCGCGGCCTCGGTATGGCTGGTCATGGCC
+GATGAATCAGAAATCTGGGATGCATTTAATAGTCTGATAGGTCTGATGGGAGGGCCAATG
+ACCGGTCTGTTCATGCTGGGCATTTTCTTTAAACGAGCAAATGCCGGGAGTGCGGTTTTA
+GGAATTATTATCAGCGTCATTACCGTGCTGGGCACACGCTATGCCACTGACCTTAACTTC
+TTCTTTTATGGGGTCATTGGCTCGCTAAGCGTGGTGATCAGCGGCGTTATTTTCGCCCCG
+TTATTTGCCCCGGCACCGCCATTGACGCTGGATGAAAAACCTGAACCAAAGGTGACATTA
+TGA
+>11111_1#11_04096
+ATGATTACACATTCTTTCGGCATCGTTAATTATTTTGTATTATTTGGCTACCTCCTGGCC
+ATGATGTTAGTCGGTGTCTATTTTTCCAGACGGCAAAAAACAGCAGACGATTATTTTCGC
+GGTGGTGGCCGGGTTCCTGGTTGGGCGGCTGGGGTCAGTGTATTTGCTACTACGTTAAGC
+TCAATTACATTTATGTCAATTCCTGCCAAAGCGTTTACTTCCGACTGGACGTTTATCATT
+GGTCAGTATCTGGCTATCGCAATTTTACCGCTGGTTTTTTATTTCTATATTCCGTTTTTT
+CGGAAATTGAAAGTCACATCAGCCTATGAATATCTCGAAGCACGGTTCGATGTGCGCTGC
+CGTCTGTTCGCCAGCATGTCATTTATGTTGTTTCATATTGGACGTATCGCCATTATCACT
+TTCCTCACCGTGCTGGCCTTGCGCCCCTTCATCGCTATAGACCCGGTGATTTTGGTACTG
+TTGATTAGTGTGATGTGTATCATTTATACCTGGATGGGGGGGAATTGA
+>11111_1#11_04097
+ATGTCACTATTAGCCAGGCTGGAACAAAGTGTACACGAAAACGGTGGGCTGATTGTCTCA
+TGCCAACCGGTACCAGGCAGCCCTATGGATAAACCTGAAATTGTGGCTGCAATGGCACAG
+GCAGCGGCTTCGGCGGGTGCGGTCGCTGTGCGCATTGAAGGCATTGAGAATCTGCGGACT
+GTTCGTCCCCATCTTTCTGTTCCTATTATTGGGATAATTAAACGTGACCTTACAGGGTCG
+CCAGTCCGTATCACTCCATATTTACAGGATGTTGACGCCCTGGCGCAGGCAGGTGCCGAT
+ATTATCGCTTTTGATGCCTCATTCCGCTCTCGCCCGGTTGATATTGATAGTTTACTGACA
+CGTATTCGCCTGCATGGATTACTGGCGATGGCAGACTGTTCAACCGTGAATGAAGGCATA
+AGTTGCCATCAGAAAGGAATCGAATTCATTGGTACAACACTGTCTGGCTATACCGGTCCC
+ATCACGCCGGTTGAGCCAGATTTGGCAATGGTGACACAACTGAGTCATGCAGGTTGTCGT
+GTTATTGCCGAGGGGCGCTATAACACGCCTGCACTGGCGGCCAATGCTATTGAGCATGGT
+GCCTGGGCAGTTACCGTTGGTTCCGCTATCACCCGTATCGAGCATATCTGTCAGTGGTTC
+AGTCACGCAGTAAAACGCTGA
+>11111_1#11_04098
+ATGAAAAATTTTAAGAAAATGATGACGCTAATGGCGCTATGTTTATCAGTTGCTATCACC
+ACATCAGGATATGCAACCACGCTTCCTGATATACCAGAACCACTGAAAAATGGTACTGGC
+GCTATTGATAATAATGGCGTGATTTATGTCGGCTTAGGTACCGCAGGGACATCCTGGTAT
+AAAATTGATCTTAAAAAGCAACATAAAGACTGGGAGCGTATAAAGTCGTTTCCTGGTGGA
+GCTCGTGAGCAATCCGTGTCGGTATTTTTAAATGATAAGCTGTATGTTTTTGGTGGCGTA
+GGGAAAAAAAACAGTGAATCACCGTTGCAGGTTTATAGCGATGTGTACAAATACTCACCG
+GTGAAAAATACATGGCAAAAAGTTGATACTATATCTCCAGTTGGATTAACAGGGCATACG
+GGAGTAAAATTAAACGAAACGATGGTACTTATTACCGGAGGGGTTAATGAGCATATCTTT
+GATAAGTATTTTATTGATATAGCGGCTGCGGATGAAAGTGAAAAAAATAAAGTCATCTAT
+AATTATTTTAATAAACCTGCCAAAGATTATTTTTTTAATAAAATCGTATTTATCTACAAT
+GCTAAAGAGAACACATGGAAGAATGCCGGTGAGCTGCCAGGCGCGGGGACGGCAGGATCG
+TCATCGGTAATGGAAAATAATTTCTTGATGCTGATTAATGGTGAGCTCAAACCGGGTTTA
+CGTACCGATGTGATTTACCGCGCCATGTGGGATAACGATAAGCTAACATGGTTGAAGAAC
+AGCCAGTTACCGCCATCGCCTGGAGAACAACAGCAGGAAGGGTTGGCCGGAGCATTTTCG
+GGCTATAGCCACGGTGTCCTGCTTGTCGGTGGTGGCGCGAATTTTCCGGGAGCAAAACAA
+AATTATACTAATGGAAAGTTTTATTCCCACGAAGGGATAAATAAAAAATGGCGAGATGAA
+GTCTATGGTTTGATTAATGGCCATTGGCAATATATGGGTAAAATGAAACAACCTCTCGGC
+TATGGTGTATCAGTAAGTTATGGTGATGAAGTTTTCCTTATTGGTGGTGAAAATGCTAAA
+GGGAAACCTGTTTCGTCTGTAACCTCCTTTACCATGCGTGATGGTAATTTATTAATAAAA
+TAA
+>11111_1#11_04099
+ATGAAAATCAACAGATATCTTCTGGGTATGGTTTCGTTTATAGCATTTTCATCATATCTA
+CAAGCGGCAACCCTTGATTATCGGCATGAATATGCTGATAGAACCAGAATTAATAAAGAC
+CGTATTGCTATAATTGAAAAGCTTCCTAACGGCATTGGTTTTTATGTCGATGCCAGCGTT
+AAATCGGGAGGAGTAGATGGTGAGCAGGATAAGCATTTAAGCGATCTCGTCGCAAACGCT
+ATAGAACTGGGCGTAAGTTATAATTATAAAGTTACGGACCATTTTGTTTTGCAGCCTGGA
+TTTATATTTGAAAGCGGTCCAGACACTTCAATTTATAAGCCTTATTTAAGGGCGCAATAT
+AATTTTGATTCTGGTGTTTATATGGCTGGTCGTTACCGTTATGACTATGCAAGGAAGACA
+GCTAACTATAATGATGATGAGAAAACGAATAGATTTGATACTTATATAGGTTATGTTTTT
+GATGAGTTGAAATTGGAATATAAATTTACCTGGATGGATAGCGATCAAATTAAATTTGAT
+AACAAAAAAACAAACTATGAACATAATGTGGCTTTAGCCTGGAAACTGAATAAGTCATTT
+ACACCATACGTTGAGGTCGGAAATGTAGCGGTGAGAAATAATACCGATGAGAGACAGACC
+CGTTATCGCGTTGGATTACAATACCACTTTTGA
+>11111_1#11_04100
+GTGATAGCAAAATTCTTCCCGTGGTATAGCGAGATAACACGTCCACAAAAAAATGCTTTA
+TTTTCAGCATGGCTGGGTTACGTTTTTGATGGCTTCGACTTTATGCTGATTTTCTACATT
+ATGTATCTGATCAAGGCTGACTTAGGATTGACAGATATGGAGGGCGCATTCCTTGCCACA
+GCGGCCTTTATTGGGCGACCATTTGGCGGGGCGCTATTTGGTCTGCTGGCAGACAAATTT
+GGCCGTAAGCCGTTAATGATGTGGTCGATAGTTGCCTATTCTGTAGGTACAGGGTTAAGT
+GGCCTGGCTTCCGGTGTAATTATGCTGACGCTTAGTCGTTTTATTGTCGGTATGGGGATG
+GCGGGGAAGTATGCTTGCGCTTCTACTTATGCCGTGGAAAGTTGGCCAAAGCATTTAAAA
+TCTAAAGCGAGCGCATTTCTGGTTTCAGGTTTCGGTATTGGTAACATCATAGCAGCCTAT
+TTTATGCCGTCATTTGCCGAAGCGTATGGTTGGCGTGCTGCTTTTTTTGTCGGTTTGCTA
+CCCGTTCTTTTAGTAATCTACATCCGGGCCAGGGCTCCTGAATCTAAAGAGTGGGAAGAA
+GCCAAACTCAGTGGTCTCGGAAAGCATTCACAAAGTGCCTGGTCAGTTTTCTCTTTGTCA
+ATGAAAGGGCTATTTAATCGAGCTCAATTTCCACTGACATTATGTGTATTTATTGTTCTG
+TTCTCTATTTTCGGCGCAAACTGGCCGATCTTTGGTCTACTGCCTACATATTTGGCGGGA
+GAGGGCTTTGATACGGGCGTGGTCTCTAATTTAATGACGGCGGCGGCATTCGGCACTGTA
+TTGGGAAATATCGTTTGGGGTCTGTGCGCAGATAGAATTGGTTTGAAGAAAACGTTCAGC
+ATTGGTCTTCTCATGTCCTTTTTATTCATTTTCCCGTTATTCAGAATTCCGCAAGATAAT
+TATTTACTGCTGGGCGCATGTTTATTCGGTTTAATGGCGACTAACGTAGGTGTTGGCGGG
+CTGGTTCCCAAATTTCTCTACGACTACTTTCCTCTTGAGGTTCGTGGTTTGGGTACCGGG
+CTTATTTATAATCTTGCTGCGACATCAGGCACATTCAATTCAATGGCGGCGACCTGGCTT
+GGAATAACAATGGGGCTAGGCGCTGCGCTAACGTTCATTGTTGCTTTCTGGACCGCAACA
+ATTCTACTCATTATTGGCCTATCCATTCCGGATAGACTAAAAGCACGTCGTGAAAGGTTT
+CAGTCAACAAAAGAATTTTAA
+>11111_1#11_04101
+ATGACGAAATACGGTGTTATAGGTACAGGTTATTTTGGCGCTGAACTGGCGCGATTTATG
+TCTAAGGTTGAAGGGGCGAAAATCACTGCGATTTACGATCCGGTAAATGCGGCTCCGATA
+GCGAAAGAGCTGAACTGTGTCGCCACTTCAACGATGGAGGCGCTTTGTACCCATCCTGAT
+GTGGATTGCGTAATTATTGCTTCACCAAATTACTTACATAAAGCGCCGGTCATTGCGGCG
+GCTAAAGCGGGTAAACACGTGTTTTGTGAAAAACCTATCGCCTTAAATTACCAGGATTGT
+AAGGATATGGTTGATGCCTGCAAAGAAGCTGGTGTTACCTTTATGGCGGGTCACGTTATG
+AACTTTTTTCACGGGGTTCGCCACGCTAAAGCGCTCATCAAAGCCGGTGAAATCGGTGAA
+GTTACACAAGTTCACACTAAACGTAATGGTTTTGAAGACGTGCAGGATGAGATCTCATGG
+AAGAAGATTCGCGCAAAGTCAGGTGGGCATCTGTACCATCACATTCACGAGCTAGATTGT
+ACACTGTTCATCATGGATGAAACCCCATCCCTGGTTTCAATGGCGGCGGGGAATGTTGCG
+CACAAAGGTGAAAAATTTGGTGATGAAGATGATGTTGTCCTAATCACCCTTGAGTTTGAA
+AGCGGTCGTTTCGCGACACTTCAGTGGGGATCATCGTTCCACTACCCTGAGCACTATGTA
+TTAATTGAGGGCACGACAGGTGCAATTCTCATTGATATGCAAAACACGGCTGGTTATCTA
+ATAAAAGCGGGCAAAAAAACACACTTTCTTGTGCATGAAAGCCAGGCGGAGGATGATGAT
+CGTCGCAACGGTAACATATCCAGCGAGATGGATGGCGCAATCGCTTATGGTAAACCCGGT
+AAACGTACGCCGATGTGGCTCTCATCAATTATGAAACTGGAGATGCAGTACTTGCATGAT
+GTGATAAACGGTCTGGAGCCAGGCGAGGAGTTTGCTAAATTGCTAACGGGAGAAGCGGCG
+ACAAATGCCATTGCTACCGCTGATGCTGCGACGCTTTCTTCAAACGAGGGGCGCAAAGTT
+AAACTCACTGAAATTCTTGGCTAA
+>11111_1#11_04103
+ATGGAGATAATTTTTTATCACCCGACATTTAACGCCGCCTGGTGGGTAAATGCGCTGGAG
+AAGGCTCTCCCACATGCGCGCGTTCGTGAATGGAAGGTCGGTGATAACAACCCCGCAGAC
+TATGCGCTTGTATGGCAGCCCCCGGTTGAAATGCTGGCCGGAAGACGCTTAAAAGCCGTC
+TTTGTGCTGGGCGCGGGGGTGGATGCAATTCTGAGTAAATTAAATGCGCATCCGGAAATG
+CTGGACGCCTCCATTCCTCTATTCCGTCTGGAAGATACCGGAATGGGCCTGCAAATGCAG
+GAGTATGCCGCCAGCCAGGTATTACACTGGTTCCGTCGTTTCGATGATTATCAGGCGCTG
+AAAAATCAGGCGCTATGGAAACCGTTGCCGGAATATACCCGCGAAGAGTTTAGCGTCGGT
+ATCATAGGCGCAGGGGTACTGGGCGCAAAAGTGGCAGAAAGTCTACAGGCGTGGGGGTTC
+CCGTTACGTTGCTGGAGTCGTAGCCGCAAATCCTGGCCTGGCGTGGAAAGTTATGTAGGG
+CGTGAAGAACTGCGCGCTTTCCTGAACCAGACGCGGGTGCTGATTAATCTGCTGCCGAAT
+ACGGCCCAAACGGTAGGAATTATTAATAGCGAATTGTTGGATCAATTGCCGGATGGCGCT
+TACGTGCTGAATCTCGCGCGCGGCGTTCATGTTCAGGAGGCGGATCTGCTGGCTGCGCTT
+GATAGCGGTAAGCTAAAAGGCGCGATGTTGGATGTCTTTAGCCAGGAACCGTTACCGCAG
+GAAAGTCCATTATGGCGCCATCCGCGAGTCGCCATGACGCCGCACATTGCGGCAGTCACC
+CGTCCGGCGGAAGCCATCGATTATATTAGCCGCACCATTACCCAGCTGGAGAAGGGAGAG
+CCGGTGACGGGGCAGGTGGATCGGGCGAGAGGATATTGA
+>11111_1#11_04104
+ATGTATCCCGTTGACCTGCATATGCATACCGTCGCCAGCACTCATGCCTACAGTACTCTG
+AGCGATTATATCGCGGAAGCCAAACGCAAAGGCATTAAACTTTTTGCGATTACCGATCAT
+GGTCCGGACATGGAAGATGCGCCGCATCACTGGCATTTTATTAACATGCGCATCTGGCCG
+CGTCTGGTTGACGGCGTGGGGATACTGCGTGGCATTGAGGCGAATATCAAGAATATTAAC
+GGTGAAATTGATTGTTCCGGAAAGATGTTCGACTCGCTGGATCTGATTATCGCAGGCTTT
+CATGAGCCCGTTTTTGCGCCGCATGATAAAGAAACCAATACTCAGGCGATGATCGCGACC
+ATCGCCAGCGGCAAGGTGCATATAATTAGTCACCCCGGAAATCCAAAGTATCCAGTGGAG
+GTTAAAGCCATCGCGCAGGCGGCGGCGAAACACCATGTAGCGCTGGAAATCAACAACTCT
+TCTTTTCTGCATTCGCGTAAAGGAAGCGAAGATAATTGCCGCGCGGTCGCTGCCGCCGTA
+CGCGATGCGGGAGGCTGGGTAGCGTTAGGCTCTGATTCCCATACGGCCTTTACGCTTGGC
+GATTTCACCGAATGCCGGAAAATTCTGGATGCGGTGAATTTTCCGGAAGATCGAATCCTG
+AACGTCTCTCCGCAGCGCTTACTGGCCTTTCTCGAATCACGCGGTATGGCGCCTGTACCG
+GAATTTGCCGAACTTTAA
+>11111_1#11_04105
+ATGAATGAGTTTTCAATCCTGTGCCGTGTGCTGGGATCGTTGTTTTACCGCCAACCGCAA
+GATCCTTTACTGGTTCCGCTGTTTACGTTAATCCGTGAAGGTAAACTGGCGGCAAACTGG
+CCGCTGGAGCAGGATGACATGCTGGCGCGTTTACAGAAAAGCTGCGATATCACGCAGATT
+TCCACTGATTACAATGCGTTATTTGTTGGGGAAGAGTGCGCGGTAGCGCCATACCGCAGT
+GCGTGGGTCGAAGGCGCGGAAGAGTCTGAGGTGCGCGCTTTTTTAACGTCGCGAGGGATG
+CCGCTGGCCGATACGCCTGCCGATCACATTGGCACTTTATTGCTCGCGGCCTCCTGGCTG
+GAAGATCAGTCTGCCGAAGATGAAAGTGAAGCGCTGGAAACCTTATTTGCCGATTATCTG
+CTTCCCTGGTGCAATACCTTCCTCGGTAAAGTTGAAGCCCATGCCGTTACGCCATTCTGG
+CGCACTCTGGCGCCGCTAACGCGTGATGCGATAGGGGCCATGTGGGATGAACTTCAGGAA
+GAAGATGAAGAATAA
+>11111_1#11_04106
+ATGATGCGCGCCATGAACATACTTCTTTCTATTGCTATCACTACGGGCATCCTTTCTGGA
+ATATGGGGATGGGTGGCCGTCTCCCTGGGGTTACTAAGCTGGGCCGGTTTTTTAGGCTGT
+ACGGCTTATTTCGCCTGTCCGCAGGGCGGCTTTAAGGGATTGTTGATTTCCGCCTGTACG
+CTGTTAAGCGGTATGGTGTGGGCGCTGGTCATTATTCACGGTAGCGCGTTGGCGCCGCAT
+CTGGAAATTGTCAGTTACGTGTTGACGGGGATCGTGGCATTCCTGATGTGTATCCAGGCA
+AAGCAGCTATTGCTTTCTTTTGTTCCGGGAACATTTATCGGCGCCTGCGCGACATTTGCA
+GGGCAGGGTGACTGGCGGTTGGTATTACCGTCGCTGGCGCTGGGGCTAATCTTTGGCTAT
+GCCATGAAAAATAGTGGGCTATGGCTGGCATCACGCCGCGAGCAACATTCAGCGAATACG
+GCGGTCACAAAATAA
+>11111_1#11_04107
+ATGCCGCGCTTACTTATTTTGGTTGCCGTTTTATTGTTGAGCGGATGCTTAACTGCCCCG
+CCGAAACAAGCTGCGAAACCGACATTAATGCCCCGCGCACAAAGTTACAAAGATTTGACG
+CACTTACCTGCTCCCACCGGTAAGATCTTTGTTTCGGTATATAACATTCAGGATGAAACG
+GGCCAATTTAAACCTTACCCGGCAAGTAACTTTTCCACGGCTGTGCCGCAGAGCGCCACC
+GCTATGTTGGTCACCGCGCTGAAAGATTCGCGCTGGTTTATCCCACTAGAACGACAAGGC
+TTACAGAATCTTTTGAATGAACGGAAAATTATTCGCGCAGCCCAGGAAAACGGCACCGTG
+GCGATGAATAACCGTATCCCGCTTCAGTCGTTGACGGCGGCAAATATTATGGTGGAAGGT
+TCTATTATTGGTTATGAAAGTAACGTCAAATCCGGCGGGGTCGGCGCAAGATATTTCGGT
+ATTGGCGCCGATACGCAGTATCAGCTGGATCAGATTGCTGTCAACCTGCGCGTGGTTAAC
+GTCAGTACGGGCGAGATCCTTTCTTCGGTGAACACCAGTAAAACGATCCTTTCCTATGAA
+GTACAGGCAGGCGTGTTCCGTTTTATTGATTACCAGCGCTTACTGGAAGGCGAAATCGGC
+TATACCTCGAACGAACCGGTGATGCTGTGTCTGATGTCAGCCATTGAAACCGGCGTTATC
+TTCCTCATTAATGATGGTATCGATCGCGGACTGTGGGATTTGCAGAATAAAGCGGACAGG
+CAAAATGATATTCTGGTGAAATACCGTGAGCTGTCAGTACCGCCAGAATCCTGA
+>11111_1#11_04108
+ATGCGTGTTAAACATGCAGTAGTGCTGCTCATGCTTTTTTCGCCATTAACCTGGGCTGGA
+AATATGACGTTCCAGTTCCGTAATCCTAACTTTGGTGGAAACCCCAATAACGGTTCCTTT
+TTATTGAATAGCGCCCAGGCGCAAAATTCATATAAAGACCCCGCTTATGATAACGATTTT
+GGTATCGAGACCCCCTCAGCGTTGGATAACTTTACGCAGGCTATTCAATCGCAAATTCTG
+GGCGGCTTGTTGACCAATATTAATACCGGAAAACCAGGACGTATGGTGACCAATGATTTT
+ATTATCGATATCGCTAATCGCGACGGACAGCTCCAGCTCAACGTCACGGACAGAAAAACG
+GGAAGAACCTCGACCATCGAAGTGTCAGGTTTACAAACTCAGTCAACCGATTTTTAA
+>11111_1#11_04109
+ATGAAACGCTATCTGACCTGGATTGTAGCAGCAGAGTTACTGTTCGCTACCGGAAACCTG
+CATGCCAATGAAGTTGAAGTCGAGGTTCCCGGATTGTTAACCGACCATACCGTCTCTTCG
+ATAGGACATGAATTCTATCGTGCATTCAGCGACAAATGGGAAAGCGAATACACCGGCAAT
+CTGACCATTAATGAAAGACCCAGTGCGCGTTGGGGAAGCTGGATCACCATAACGGTAAAT
+CAGGACGTTATTTTCCAGACCTTTTTATTTCCAATGAAAAGAGACTTCGAGAAAACCGTC
+GTCTTCGCATTAGCGCAAACAGAGGAAGCATTAAATCGCCGACAAATAGATCAAACGCTA
+TTAAGTACGAGTGATTTAGCGCGTGATGAATTCTAA
+>11111_1#11_04110
+ATGTTTAATGAAGTCCATAGTAGTCATGGTCACACACTATTGTTGATCACAAAGCCATCT
+CTGCAAGCTACGGCATTATTGCAACATTTAAAGCAATCGCTGGCCATAACCGGAAAACTG
+CATAATATTCAACGTTCTCTGGAAGATATCTCAGCCGGTTGCATTGTTTTAATGGATATG
+ATGGAAGCGGATAAGAAGCTTATCCACTATTGGCAGGATAATTTAAGCCGCAAAAACAAT
+AATATAAAAACATTATTGTTAAATACCCCTGACGATTATCCCTACCGTGAAATTGAAAAC
+TGGCCTCATATTAACGGCGTGTTTTACGCCACTGAAGACCAGGAACACGTGGTCAGCGGA
+TTACAGGGTATTCTGCGGGGCGAATGCTATTTTTCACAAAAATTAGCCAGTTACCTGATT
+ACACACTCAGGAAATTACCGCTACAACAGCACCGAGTCCGCATTACTCACTCATCGCGAA
+AAAGAGATCCTCAATAAGTTACGTATTGGTGCCTCTAATAATGAAATCGCCAGGTCGCTA
+TTTATCAGCGAGAATACGGTTAAGACACATCTTTATAATCTTTTCAAAAAGATAGCTGTC
+AAAAATCGCACCCAGGCAGTTTCATGA
+>11111_1#11_04111
+ATGAAAAACAAATTGTTATTTATGATGTTGACAATACTGGGTGCGCCTGGGATTGCAACC
+GCGACAAATTATGATCTGGCTCGTTCAGAGTATAATTTTGCGGTAAATGAATTAAGCAAG
+TCTTCATTTAATCAGGCGGCCATTATTGGTCAAGTCGGCACGGATAATAGTGCCAGAGTA
+CGCCAGGAAGGATCAAAACTATTGTCCGTTATTTCACAAGAAGGAGAAAATAATCGGGCG
+AAAGTCGACCAGGCAGGGAATTATAACTTTGCGTATATTGAGCAAACGGGCAATGCCAAC
+GATGCCAGTATATCGCAAAGCGCTTACGGTAATAGTGCGGCTATTATCCAGAAAGGTTCT
+GGAAATAAGGCCAATATTACCCAGTACGGTACGCAGAAAACAGCAGTTGTAGTGCAGAAA
+CAGTCGCATATGGCTATTCGCGTCACCCAACGCTAA
+>11111_1#11_04112
+ATGAAACTTTTAAAAGTGGCAGCATTCGCAGCAATCGTAGTTTCTGGCAGTGCTCTGGCT
+GGCGTCGTTCCACAATGGGGCGGCGGCGGTAATCATAACGGCGGCGGCAATAGTTCCGGG
+CCGGATTCCACGTTGAGCATTTATCAGTACGGTTCCGCTAACGCTGCGCTTGCTCTGCAA
+AGCGATGCCCGTAAATCTGAAACGACCATTACCCAGAGCGGTTATGGTAACGGCGCCGAT
+GTAGGCCAGGGTGCGGATAACAGTACTATTGAACTGACTCAGAATGGTTTCAGAAACAAT
+GCCACCATCGACCAGTGGAACGCTAAAAACTCCGATATTACTGTCGGTCAATACGGCGGT
+AATAACGCCGCGCTGGTTAATCAGACCGCATCTGATTCCAGCGTAATGGTGCGTCAGGTT
+GGTTTTGGCAACAACGCCACGGCTAACCAGTATTAA
+>11111_1#11_04113
+ATGCATACTTTATTGCTCCTTGCCGCACTTTCAAATCAGATTACGTTTACCACGACTCAG
+CAAGGCGATATTTACACGGTGATCCCTCAGGTCACATTAAACGAACCCTGCGTCTGTCTG
+GTGCAAATTCTCTCTGTGCGCGACGGCGTCGGGGGACAAAGCCATACACAGCAAAAACAA
+ACGCTATCTTTACCTGCTAATCAACCGATTGAGTTGTCTCGTCTTAGTGTAAATATATCT
+TCAGAGGACTCGGTTAAAATTATTGTTACTGTTTCGGACGGACAATCACTGCATTTATCA
+CAACAATGGCCGCCTTCTGCACAGTAG
+>11111_1#11_04114
+ATGTCCGTAATCAAGAAAAATATCCCTGCCATAGGCCTGTGTATCTGCGCTTTTTTTATC
+CATTCTGCGGTAGGGCAACAAACGGTACAGGGCGGCGTTATCCATTTTCGCGGCGCGATT
+GTTGAGCCACTGTGCGATATTTCTACTCACGCCGAAAATATTGATTTAACCTGCCTACGC
+GAAGGTAAAAAGCAAATGCACCGGATAGACCTTCGGCAGGCATCTGGATTACCGCAGGAT
+ATTCAGTCCATTGCGACGGTACGGCTGCATTATCTCGATGCGCAAAAAAGCCTGGCGGTG
+ATGAATATTGAGTACCGTTAA
+>11111_1#11_04115
+ATGACATCACGTCTTCAGGTCATACAGGGTGATATCACTCAACTTAGCGTCGATGCGATT
+GTGAATGCCGCTAACGCATCATTAATGGGCGGCGGTGGCGTAGACGGCGCAATTCATCGC
+GCGGCGGGGCCGGCATTGCTGGACGCCTGTAAACTCATCCGTCAGCAACAGGGCGAATGT
+CAGACGGGACATGCGGTTATCACGCCTGCTGGCAAGCTTTCGGCAAAGGCGGTTATTCAC
+ACAGTGGGGCCCGTCTGGCGAGGCGGCGAACACCAGGAAGCTGAGCTACTCGAAGAGGCA
+TACCGGAATTGTTTGCTGCTTGCCGAGGCGAATCACTTTCGTTCCATCGCTTTTCCGGCA
+ATCAGTACCGGCGTTTATGGCTATCCACGCGCCCAGGCCGCTGAAGTCGCCGTCAGGACG
+GTTTCAGATTTTATTACCCGTTACGCTCTGCCTGAACAGGTATACTTTGTCTGTTATGAT
+GAAGAAACTGCCCGGCTTTACGCAAGATTACTTACTCAGCAAGGCGACGACCCTGCCTGA
+>11111_1#11_04116
+ATGAAGAAACTGCCCGGCTTTACGCAAGATTACTTACTCAGCAAGGCGACGACCCTGCCT
+GATAAAACACGCCTGGAGCGTGCCGTTGAACCGCTATGCGCGCGCCATCCCGGAGAGTGC
+GGCATTCTTGCGCTGGATAACAGTCTGGACGCTTTTGCCGCCCGCTACCGCCTGACCGAA
+ATGGCGGCGCGGACGCTGGATGTGCAGTATTATATTTGGGAAGACGATATGTCCGGGCGG
+CTGCTCTTTTCGGTTCTGCTGTCGGCGGCGAAGCGCGGCGTTCATGTTCGTCTGCTGCTG
+GATGATAACAATACGCCTGGTCTGGATGATACGTTGCGCTTGCTGGATAGCCATCCTAAT
+ATCGAAGTTCGTCTGTTTAATCCTTTCTCTTTTCGTACGCTACGCGCGCTGGGATATTTG
+ACGGATTTTGCGCGGCTGAATCGGCGGATGCACAATAAAAGTTACACTGCCGACGGCGTA
+GTGACGCTGGTCGGTGGGCGCAACATCGGCGATGCCTATTTCGGCGCTGGCGAGGAGCCG
+CTATTTTCCGATCTGGACGTGATGGCCATTGGCCCGGTGGTCAATGATGTCGCCAATGAT
+TTTGAACGTTACTGGCGCTGTAGTTCAGTGTCGACATTGCAGCAAGTATTATCCCTTTCT
+GAGCAGGAACTGACGCAGCGTATCGAACTTCCCGAATCCTGGTATAACGATGAGATCACC
+CGCCGTTATCTGCATAAGCTGGAAACCAGCCAGTTTATGGCGGATCTCGATCGCGGAACG
+TTGCCGCTGATTTGGGCAAAAACACGCTTGCTTAGCGATGACCCTTCTAAAGGCGAGGGG
+AAGGCGCAGCGCCATTCGCTTCTTCCGCAGCGATTATTTGACGTGATGGGGTCGCCGACG
+GAGCGTATCGACATTATTTCCGCTTACTTTGTCCCTACGCGCGCAGGCGTGGCGCAGTTG
+CTTAATCTGGTCAGGAAAGGTGTGAAGATCGCCATCTTAACTAACTCTCTGGCGGCCAAC
+GATGTGGCGGTCGTTCACGCAGGGTACGCGCGCTGGCGCAAGAAATTACTGCGCTATGGC
+GTGGAGCTCTACGAACTGAAACCGACCCGCGAACATGAAACCGCCGTACATGATCGCGGA
+CTCACCGGGAACTCAGGTTCCAGCTTACATGCTAAAACGTTCAGTATTGATGGTAGTAAG
+GTGTTTATCGGGTCGCTTAATTTTGATCCCCGTTCAACGCTTTTAAATACCGAAATGGGC
+TTTGTCATTGAAAGTGAAACGCTGGCGACGCTTATTCATAAGCGTTTTACGCAGAGCCAA
+CGCGATGCGGCCTGGCAACTGCGGCTGGATCGCTGGGGACGAATTAACTGGATCGATCGT
+CAGCAAGAAGAGGAAAAGGTGTTAAAGAAAGAACCCGCTACGCGTTTCTGGCAGCGAGTT
+CTGGTACGGTTGGCGGCAATTTTACCTGTGGAATGGTTGCTGTGA
+>11111_1#11_04117
+ATGAGCTCTGTACCCGCGCCGCGTGAATATTTTCTTGACTCTATCCGCGCATGGCTGATG
+TTGTTAGGGATTCCCTTTCATATCTCGTTGATCTATTCCACTCACAGTTGGCATGTCAAT
+AGCGCCGCGCCATCGTGGTGGCTAACCCTGTTTAACGATTTTATCCACGCTTTTCGTATG
+CAGGTGTTTTTTGTTATTTCTGGTTATTTTTCGTACATGTTATTTTTACGTTATCCATTA
+AAACACTGGTGGAAAGTACGGGTAGAACGTGTGGGTATTCCCATGCTTACCGCAATCCCT
+TTGCTTACCTTGCCGCAATTTATCCTGTTGCAATATGTCAAAGAGAAAACAGAGAACTGG
+CCTACACTCTCTGCCTATGAAAAATATAATACGTTAGCGTGGGAACTCATTTCACATCTG
+TGGTTTTTACTGGTGCTGGTGATATTAACCACCGTCAGCATCGGGATTTTTACCTGGTTC
+CAAAAAAGGCAGGAAACAAGCAAGCCTCGTCCCGCCGCTATTTCGCTGGCCAAACTTTCG
+CTTATTTTTTTCCTGCTGGGGGTGGCGTACGCTGCTATCAGGCGCATTATATTCATCGTA
+TATCCGGCAATCCTCAGTGACGGCATGTTCAATTTTATTGTGATGCAAACGCTATTTTAT
+GTGCCGTTTTTTATTCTCGGCGCGTTGGCCTTCATTCACCCCGATCTGAAAGCGCGCTTC
+ACCACGCCCTCACGCGGATGCACTTTAGGCGCTGCCGTTGCTTTTATCGCGTATCTGCTG
+AATCAACGTTATGGGAGCGGCGACGCCTGGATGTACGAAACCGAATCCGTGATTACGATG
+GTAATGGGGCTATGGATGGTGAACGTGGTATTTTCACTGGGGCATCGCTTGTTAAACTTT
+CAGTCCGCGCGTGTCACCTATTTCGTGAATGCTTCGCTGTTTATTTATCTGGTGCATCAT
+CCCTTAACGCTTTTCTTTGGCGCGTATATTACACCGCATATCTCCTCCAACCTGATCGGG
+TTCTTGTGCGGGCTGATATTTGTTATGGGTATTGCGTTAATTCTGTATGAAATTCATTTA
+CGCATCCCGCTCCTGAAATTTCTCTTTTCAGGTAAACCGCCGGTAAAACAAGAAAGCCGC
+GCCGCGATCGGGTAG
+>11111_1#11_04118
+ATGAAACATAAACGACAAATGATGAAAATGCGTTGGTTGGGCGCAGCTATTATGTTAACG
+CTCTACGCATCATCGAGCTGGGCGTTCAGTATTGATGACGTGGCAAAACAAGCTCAATCT
+TTAGCCGGGAAAGGCTATGAGGCGCCTAAAAGCAACTTGCCCTCCGTTTTCCGCGACATG
+AAATATGCGGATTATCAGCAGATCCAGTTTAACAGCGATAAAGCCTACTGGAACAACTTA
+AAGACCCCTTTTAAGCTCGAATTTTACCATCAGGGGATGTACTTCGATACGCCGGTCAAG
+ATTAACGAAGTGACGGCGACGACGGTCAAAAGAATCAAATACAGCCCGGATTACTTCAAT
+TTTGGCAATGTTCAGCACGATAAAGACACGGTAAAAGATTTAGGCTTCGCCGGGTTCAAA
+GTCCTGTACCCCATTAACAGTAAAGATAAGAACGACGAAATCGTCAGTATGCTTGGCGCC
+AGCTATTTCCGCGTTATCGGCGCAGGCCAGGTGTATGGCTTATCTGCGCGCGGCCTGGCG
+ATTGATACCGCCTTACCATCTGGTGAAGAGTTTCCCCGCTTTCGCGAGTTCTGGATTGAG
+CGTCCAAAACCCACCGATAAGCGTTTGACCGTCTATGCATTACTGGATTCTCCGCGCGCG
+ACCGGCGCTTACCGTTTTGTGATCATTCCTGGCCGCGATACCGTGGTGGACGTGCAGTCA
+AAAGTCTATCTGCGCGATAAGGTGGGCAAGCTGGGCGTTGCGCCATTAACCAGTATGTTC
+CTGTTTGGGCCAAACCAGCCGTCGCCGACGACCAACTATCGTCCGGAATTGCATGACTCG
+AACGGCTTATCCATTCATGCGGGTAATGGCGAGTGGATTTGGCGTCCGCTGAACAATCCA
+AAACACCTCGCTGTGAGCAGCTATGCGATGGAAAACCCTCAGGGATTCGGCCTGTTGCAG
+CGTGGTCGCGAGTTCTCGCGCTTTGAAGATTTAGACGATCGCTATGACCTGCGTCCAAGC
+GCCTGGATTACCCCGAAAGGCGACTGGGGCAAAGGTAAGGTTGAACTGGTTGAAATTCCG
+ACCAATGATGAAACCAACGATAACATCGTCGCTTACTGGACTCCGGATCAACTGCCGGAA
+CCGGGTAAAGAGATGAACTTCAAGTACACTCTGACCTTCAGCCGCGATGAAGATAAACTT
+CATGCGCCGGATAATGCCTGGGTGCTGCAAACACGCCGCTCAACGGGCGACGTTAAACAG
+TCGAATCTGATTCGCCAGCCCGACGGCACTATTGCCTTTGTGGTGGATTTCGTTGGCGCC
+GACATGAAAAAACTGCCGCCGGATACGCCCGTCGCTGCACAAACCAGCATTGGCGATAAC
+GGTGAAATCGTTGACAGTAATGTACGCTATAACCCAGTCACTAAAGGCTGGCGTTTAATG
+CTGCGCGTGAAAGTCAAAGACGCGAAGAAAACCACGGAAATGCGTGCCGCATTGGTGAAT
+GCCGATCAGACGCTAAGTGAAACCTGGAGCTACCAGTTACCTGCCAATGAATAA
+>11111_1#11_04119
+ATGAATAAAACAACTGAGTATATTGACGCACTGCTGCTTTCTGAACGTGAGAAAGCGGCA
+TTGCCGAAAACTGACATCCGCGCCGTGCATCAGGCGCTGGATGCCGAGCATCGGACTTAC
+TCGCGAGAAGACGATTCACCGCAGGGTTCCGTAAAAGCCCGCCTTGAACACGCCTGGCCG
+GATTCATTGGCGAAGGGGCAGTTAATTAAAGATGATGAAGGGCGCGATCAGTTGCAGGCT
+ATGCCAAAAGCGACGCGCTCTTCGATGTTTCCTGATCCCTGGCGAACCAACCCGGTTGGC
+CGTTTCTGGGATCGCCTGCGTGGGCGGGATGTAACGCCGCGCTATGTTTCTCGTCTGACA
+AAAGAAGAGCAGGCGAGTGAGCAAAAATGGCGTACCGTCGGCACTATACGCCGCTATATT
+TTGTTAATTTTGACTCTGGCGCAAACCGTCGTCGCGACCTGGTATATGAAGACCATTCTG
+CCCTATCAGGGATGGGCGCTCATCAATCCTATGGATATGGTGGGGCAGGATATTTGGGTC
+TCCTTTATGCAGCTCCTGCCCTACATGCTGCAAACCGGTATCCTGATTTTGTTTGCCGTG
+CTGTTCTGCTGGGTGTCTGCCGGATTCTGGACGGCGCTGATGGGCTTCCTGCAACTGCTT
+ATCGGGCGCGATAAGTACAGTATCTCCGCGTCTACGGTTGGCGATGAGCCCCTCAATCCG
+GAACACCAGACGGCGCTGATCATGCCTATCTGTAATGAAGACGTTAGCCGCGTTTTCGCC
+GGTCTGCGCGCGACCTGGGAGTCCGTTAAAGCCACAGGCAACGCCGCGCATTTTGACGTC
+TATATCCTTAGCGATAGTTATAACCCGGATATCTGCGTGGCGGAGCAAAAGGCGTGGATG
+GAGCTCATCGCGGAAGTGCAGGGCGAAGGCCAAATTTTTTACCGTCGCCGCCGCCGCCGT
+ATGAAACGCAAAAGCGGCAATATTGACGATTTTTGCCGCCGCTGGGGCAATCAGTACAGC
+TATATGGTGGTGCTGGACGCGGACTCAGTGATGAGCGGCGAGTGTCTGAGCGGGCTGGTG
+CGCCTGATGGAAGCGAACCCTAACGCCGGGATTATCCAGTCTTCGCCGAAAGCGTCGGGG
+ATGGATACTCTGTATGCCCGCTGCCAACAGTTCGCGACCCGTGTTTATGGACCGCTGTTT
+ACCGCCGGGCTGCACTTCTGGCAGTTGGGGGAGTCGCACTACTGGGGGCACAATGCCATT
+ATCCGCGTGAAGCCGTTTATCGAGCACTGCGCTCTGGCGCCGCTGCCGGGAGAAGGTTCG
+TTCGCCGGATCGATTCTTTCCCACGACTTTGTGGAGGCGGCGCTAATGCGTCGGGCAGGG
+TGGGGCGTCTGGATTGCCTACGATCTCCCCGGCTCCTATGAAGAGCTGCCGCCAAACCTG
+CTGGATGAGCTTAAACGCGACCGCCGCTGGTGTCACGGCAACCTGATGAACTTTCGTCTG
+TTCCTGGTGAAAGGAATGCACCCGGTGCATCGCGCCGTGTTCCTGACCGGGGTAATGTCA
+TACCTGTCCGCGCCGTTATGGTTTATGTTCCTCGCGCTTTCTACCGCGCTGCAGGTCGTT
+CATGCGTTAACAGAGCCGCAATATTTCCTTCAGCCGCGCCAGCTTTTTCCGGTCTGGCCG
+CAGTGGCGTCCGGAACTGGCAATCGCGCTGTTTGCGTCAACGATGGTGCTGCTGTTCCTG
+CCGAAGCTGCTCAGTATTATGCTGATCTGGTGTAAAGGCACCAAAGAGTATGGCGGTTTC
+TGGCGCGTTACGCTGTCGCTATTGCTGGAAGTGCTGTTCTCCGTGTTGCTGGCGCCGGTG
+CGTATGCTGTTTCATACCGTGTTTGTGGTCAGCGCGTTCCTCGGCTGGGAAGTGGTCTGG
+AACTCACCGCAACGCGACGATGATTCTACGCCGTGGGGAGAAGCCTTTATGCGTCACGGC
+TCTCAACTGCTGCTGGGGCTGGTCTGGGCGGTGGGTATGGCGTGGCTGGATTTACGCTTT
+CTGTTCTGGCTGGCGCCGATTGTCTTTTCGCTGATTCTGTCGCCATTTGTTTCGGTGATC
+TCCAGTCGTTCAACGGTAGGATTACGCACCAAACGCTGGAAGCTGTTCCTGATCCCGGAA
+GAGTATTCGCCGCCTCAGGTGTTGGTCGATACCGATAAATATCTGGAGATGAATCGCCGC
+CGTATTCTGGACGATGGCTTTATGCATGCGGTATTTAACCCGTCGCTTAATGCGCTGGCG
+ACCGCGATGGCCACCGCGCGTCACCGCGCCAGTAAGGTGCTGGAAATAGCCCGCGATCGT
+CATGTGGAGCAGGCGCTAAACGAAACGCCGGAGAAACTGAACCGCGATCGGCGTCTGGTT
+TTGCTCAGCGATCCGGTGACGATGGCGCGTTTACACTATCGGGTCTGGAATGCGCCAGAG
+AGATACTCTTCCTGGGTAAACCATTATCAGTCTCTCGTCCTGAATCCGCAGGCGTTGCAG
+GGACGAACATCGTCAGCGGGATAA
+>11111_1#11_04120
+GTGCGTATATTCGCGGTGAGCATAATGGTGATTACCCTGAGCGGCTGCGGCAGTATTATC
+AGCAGAACGATCCCCGGACAAGGACACGGCAACCAGTATTACCCTGGCGTGCAGTGGGAT
+ATGCGTGATTCCGCATGGCGCTATATCACTATCCTCGATCTGCCCTTCTCACTGATCTTC
+GATACACTGCTACTGCCGCTCGATATTCACCACGGGCCTTATGAGTAA
+>11111_1#11_04121
+ATGACCATGTATGCCACGCTGGAAGAAGCTATCGATGCAGCCCGGGAAGAATTTCTGGCT
+GACCATCCAGGCCTCGAACAAGACGAAGCGAATGTGCAGCAGTTCAACGTTCAGAAATAT
+GTACTGCAGGATGGGGACATCATGTGGCAGGTCGAATTTTTCGCCGATGAAGGTGAAGAT
+GGCGAATGTCTGCCGATGCTGAGTGGTGAAGCCGCACAGAGCGTGTTTGACGGCGATTAT
+GATGAGATAGAGATCCGCCAGGAATGGCAGGAAGAGAATACTTTGCATGAATGGGATGAA
+GGGGAATTCCAGCTTGAACCCCCGCTTGATACCGAGGAAGGCCGTACTGCGGCAGACGAA
+TGGGATGAGCGTTAA
+>11111_1#11_04122
+ATGTCACCCTCTGATGTCCCCATAAACTGGAAACGCAATCTAACCGTTACCTGGCTGGGC
+TGTTTTTTAACCGGCGCGGCATTCAGTCTGGTCATGCCTTTTCTCCCTCTCTACGTTGAG
+CAACTCGGCGTAACAGGCCATAGCGCGCTCAACATGTGGTCCGGGCTGGTCTTTAGTATT
+ACGTTCCTCTTTTCAGCTATCGCTTCCCCTTTTTGGGGCGGTCTGGCGGATCGTAAAGGG
+CGTAAGATCATACTGTTGCGTTCCGCTCTCGGCATGGCCATTGTGATGCTGTTAATGGGC
+ATGGCGCAAAATATCTGGCAATTTCTGATCCTCCGCGCGTTATTAGGCCTGCTGGGCGGA
+TTTATTCCCAACGCCAATGCGCTCATCGCCACTCAGGTGCCGCGCCACAAAAGCGGCTGG
+GCGTTAGGGACGCTCTCTACTGGCGGCGTCAGCGGCGCTCTGCTTGGCCCACTTGCGGGC
+GGTCTGCTCGCCGACCATTACGGCCTTCGCCCGGTCTTTTTTATTACCGCCAGCGTTTTG
+TTTATCTGTTTTCTGCTCACCTTCTTTTTTATTCGCGAGAATTTCCTGCCGGTGAGCAAA
+AAAGAGATGCTTCACGTTCGGGAAGTGGTCGCCTCGTTAAAAAATCCCCGCCTGGTGTTA
+AGCCTGTTTGTCACCACGCTGATTATTCAGGTGGCGACGGGGTCTATTGCGCCCATCCTG
+ACGCTCTATGTGCGCGAACTCGCGGGAAATGTCAGTAATATTGCGTTCATTAGCGGGATG
+ATAGCGTCCGTTCCCGGCGTGGCGGCATTACTTAGCGCCCCCCGGCTCGGCAAGCTCGGC
+GACAGAATTGGCCCGGAAAAGATCCTTATCGTCGCGCTGATTATTTCCGTACTGCTGCTG
+ATTCCAATGTCTTTTGTGCAAACGCCGTGGCAGCTCGCGCTATTGCGGTTTCTGCTTGGC
+GCGGCGGATGGCGCGCTGCTGCCAGCCGTTCAAACTCTGCTGGTTTACAACTCTACCAAC
+CAGATAGCCGGGCGCATATTCAGTTACAACCAATCTTTCCGCGATATCGGCAACGTCACC
+GGCCCTCTCATGGGTGCCGCAATTTCCGCGAGCTATGGCTTCCGCGCCGTATTCTGCGTC
+ACGGCAGGCGTGGTGTTGTTCAATGCTATCTATTCATGGAACAGCTTACGACGGCGCAGA
+CTGGCAATAGAATGA
+>11111_1#11_04123
+ATGACGAAGTTGCCTAAGTTCTCCGTGGCCTTACTGCACCCGCGCTATTGGTTAACCTGG
+TTGGGTATAGGCGCGCTTTGGTTGGTCGTGCAACTCCCCTACCCGGTCATCTATAAATTG
+GGTTGCGCATTGGGCCACCTGGCGCGACGCGTAATGAAACGCCGCGCGAAAATCGCCTAT
+CGCAACCTTGAATTATGCTTTCCGGAAATGAGCGCGCAGGAACGCCACACCATGGTGGTC
+AAAAACTTTGAATCCGTCGGTATGGGCGTGATGGAAACCGGCATGGCCTGGTTCTGGCCC
+GATCGGCGAGTGAACCGCTGGATGGAAGCGAGCGGTCTGGAGCATATCCGTGAAGTTAAG
+GCGCAGGGGCTGGGGTTCATTCTGGTAGGAATACATTTCCTTACCCTTGAGTTTGGCGCC
+CGCATGTTTGGTATGCATAACCCGGGTATCGGCGTTTATCGCCCGAATGATAATCCGTTG
+CTCGACTGGTTACAGACCTGGGGGCGCTTACGCTCCAATAAATCGATGTTGGATCGCAAA
+GATCTGAAAGGTATGGTTAAGGCATTGAAAAGCGGCGAATTGATCTGGTATGCGCCGGAT
+CACGATTATGGCCCGCGCGCCAGCGTCTTTGTACCGTTATTCGCCGTCGACCAGGCCGCT
+ACGACCTCCGGTACCTGGATGCTCGCGCGCATGTCTAAAGCCTGTATTATCCCCTCCGTG
+CCTCGCCGTAAACCCGACGGGAAAGGCTACGAACTGATCATCCTTCCTGCGGAATATTCG
+CCTCCGCTGGAGAGCGCAGAAGCGACTGCCGCATGGATGAATAAGATTGTTGAGCAGTGC
+ATTATGATGGCGCCAGAGCAGTATATGTGGCTGCATCGCCGCTTTAAAACTCGCCCTGAA
+GGCGTACCGTCGCGCTATTGA
+>11111_1#11_04124
+ATGCCAGTGTTACACAACCGCATCTCTAATGACGAGCTGAAAGCCAAAATGCTGGCGGAA
+AGCGAGCCGCGTACGACAATTTCTTTTTATAAATATTTCACTATCGCCTCGCCGCAACAG
+ACGCGGGACGCGTTGTATCAGGTGTTTACGGCGTTGGACGTTTTTGGTCGCGTTTACCTG
+GCGCATGAGGGCATCAATGCGCAAATCAGCGTGCCGCAAAGCAAGGTTGAGACCTTTCGT
+CAACAGCTTTATACGTTCGACCCCGCGCTGGACGGGGTGCGTTTAAATATCGCGCTGGAG
+GATGACGGAAAGTCATTTTGGGTGCTGCGTATGAAAGTTCGCGACCGTATCGTCGCTGAC
+GGTATTGACGATCCGAGTTTTGACGCCAGTAATGTCGGCGATTATCTGAAGGCGGCAGAT
+GTGAATGCGATGCTGGACGATCCTGACGCGGTCTTTATTGATATGCGCAACCACTATGAG
+TATGAAGTCGGCCATTTCGAAAATGCTCTGGAAATCCCGGCGGATACGTTTCGTGAACAG
+TTGCCAAAAGCGGTTGAAATGCTGCGGGAACATGCAGATAAAAAGATAGTGATGTACTGT
+ACCGGCGGTATTCGTTGTGAGAAAGCCAGCGCCTGGATGAAACACAACGGTTTCAATAAA
+GTCTGGCATATTGAGGGTGGCATCATTGAGTACGCCCGTCGCGCGCGCGAGCAGGGGCTT
+CCCGTTCGCTTTATCGGCAAAAACTTTGTATTTGATGAGCGAATGGGCGAGCGCATCTCG
+GATGAGGTTATCGCGCATTGCCATCAGTGCGGCGTGTCCTGCGATAGCCATACCAACTGC
+AAAAACGACGGTTGCCATCTGCTGTTTATCCAGTGTCCGCAGTGCGCCAGTAAATTTAAC
+GGCTGCTGTAGTGAACAATGCTGTGAAGAGTTGGCCTTGCCGGAGGAAGAACAGCGCCGA
+CGTCGCGCGGGTCGTGAGAACGGCAACAAAATTTTTAATAAATCGCGGGGTCGGCTTAAT
+AGCAAACTGAGCATTCCCGATCCGGCTGAGTAA
+>11111_1#11_04125
+ATGAAAAAAAACCTGCTGGGATTCACCCTCGCATCCTTGTTATTCACGACCGGTTCCGCC
+GTGGCGGCGGAGTATAAAATTGATAAAGAAGGCCAACATGCGTTCGTCAATTTCCGCATC
+CAGCATCTGGGCTACAGCTGGCTATACGGCACCTTTAAAGATTTCGACGGCACGTTCACT
+TTTGACGAAAAAAATCCGTCAGCAGACAAAGTGAATGTGACCATTAACACCAATAGCGTC
+GACACTAACCATGCCGAACGTGACAAACACCTGCGTAGCGCGGAGTTTCTTAATGTTGCG
+AAATTCCCGCAGGCAACCTTCACCTCTACCAGCGTGAAAAAAGAGGGCGATGAACTGGAT
+ATTACCGGCAATCTGACGCTCAATGGCGTGACTAAACCGGTGACGCTGGAAGCGAAGCTG
+ATGGGCCAGGGCGACGATCCGTGGGGCGGTAAGCGCGCGGGCTTTGAGGCCGAAGGAAAA
+ATTAAGCTGAAAGATTTCAATATAACTACCGATCTCGGCCCAGCCTCACAAGAGGTGGAG
+CTTATCATCTCAGTAGAAGGCGTTCAGCAGAAGTAA
+>11111_1#11_04126
+ATGTTACTGATGATGGCGCTGATCGTGCGTATTATCTGGCGGCTTTATTCTCCGCCGCCC
+GTTGCGTTGACCAGCTATTCCCGTTTAACGCGCATTGGCGCCGCCGCGGGTCATATCCTT
+CTGTATCTCCTGCTCTTTGCGATAATCATTAGCGGCTACCTGATTTCCACCGCCGACGGT
+AAACCGATTAGCGTCTTTGGCTGGTTTGAGATTCCGGCCACGCTTACGGACGCGGGCGCG
+CAGGCTGACATCGCCGGAACACTGCATCTGTGGTTTGCCTGGTCGCTGGTCATTATCTCG
+CTCTCGCATGGGGTTATGGCGCTAAAACACCATTTCATCGATAAAGACGACACACTGAAA
+CGTATGACAGGAATGTCGTCATCTGACTATGGAGCTCAAAAATGA
+>11111_1#11_04128
+ATGAAATACGACCTTATTATTATCGGCAGCGGTTCGGTTGGCGCCGCCGCTGGTTATTAC
+GCCACCCGCGCCGGGCTAAAGGTCCTGATGACCGATGCGCATATGCCGCCTTATCAACAG
+GGCAGCCACCACGGCGATACCCGTCTTATCCGCCACGCTTATGGTGAAGGCGAAAAATAT
+GTCCCGCTGGTGCTTCGCGCCCAGACGCTTTGGGATGAGCTCTCCACACACAATGAAGAG
+CCTATTTTTGTCCGCTCCGGCGTCGTCAACCTCGGCCCGGCCGATTCCGCTTTCTTAGCC
+AACGTCGCACGAAGCGCGCAACAGTGGCAATTGAACGTCGAGCGCCTGGACGCGACGGCC
+CTCATGACGCGCTGGCCGGAAATTCGCGTGCCCGATAATTATATCGGGCTGTTTGAAGCT
+GACTCCGGTTTCCTGCGCAGCGAATTAGCCATTACCACATGGCTTCGTCTGGCCCGAGAG
+GCAGGCTGCGCACAGCTATTCAACAGCCCGGTAAGCCATATTCACCATGATGATAACGGT
+GTGACGATAGAGACGAGTGAAGGCTGCTACCACGCCAGCAAAGCGCTGATTAGCGCGGGC
+ACCTGGGTCAAAACGCTGGTACCGGAGCTGCCCGTTCAGCCCGTACGTAAAGTTTTTGCC
+TGGTTTAAGGCGGATGGACGTTACAGCACTAAAAACCGCTTTCCGGCCTTTACCGGCGAA
+ATGCCCAACGGCGATCACTATTACGGTTTCCCGGCGGAGAACGACGAGTTAAAAATCGGC
+AAACACAATGGCGGGCAGCGAATACAGGCACCGGAAGAGCGCAAGCCCTTTGCCGCCGTT
+GCCAGCGATGGCGCGGAAGCATTTCCTTTCCTGCGTAACGTACTGCCGGGTATCGGCGGT
+TGTTTACATGGGGCGGCATGTACCTATGATAATTCGCCGGACGAGGATTTTATTATCGAT
+ACGCTGCCTGGCCATGAGAATACGCTTGTCATCACTGGACTCAGCGGACATGGTTTTAAA
+TTCGCCCCGGTGTTAGGAGAAATCGCTGCGGATTTTGCGTTGGGAAAAACGCCCTCCTTT
+GATCTGACGCCGTTCCGGCTTTCCCGTTTTAGCCAATAA
+>11111_1#11_04129
+ATGGAAAAGAATAATGAAGTCATTCAGACCCATCCGCTTGTAGGATGGGACATCAGCACC
+GTCGATAGCTATGATGCGCTGATGCTGCGTTTACACTACCAGACCCCAAATCGTCCGGAA
+CCGGAAGGGACTGAAGTTGGTCAAACGCTCTGGTTAACGACAGATGTAGCCAGGCAATTT
+ATTTCAATATTAGAAGCCGGCATCGCCAAAATAGAATCAGGCGATTACCAGGAAAACGAG
+TATCGTCACCATTAG
+>11111_1#11_04131
+ATGACTGCACCATCCCAGGTTTTAAAGATCCGCCGCCCGGACGACTGGCACGTTCACCTT
+CGCGATGGCGACATGTTAAAAACGGTCGTACCCTATACCAGCGAAATTTATGGTCGCGCT
+ATCGTGATGCCGAACCTGGCGTCCCCCATTACGACCGTTGATGCAGCGATCGCCTACCGC
+CAGCGTATTCTCGATGCGGTGCCCGCCGGGCATGATTTCACGCCGTTAATGACCTGCTAT
+TTAACGGATTCGCTCGATGCCGATGAACTGGAGCGTGGTTTCCATGAAGGCGTGTTTACT
+GCGGCCAAGCTTTACCCGGCCAATGCCACCACTAACTCCAGTCATGGCGTAACGTCAGTC
+GACGCTATCATGCCGGTACTGGAGCGGATGGAAAAACTCGGAATGCCATTGCTGGTCCAC
+GGTGAGGTGACCCATGCGGATGTTGATATCTTCGATCGCGAAGCGCGTTTTATCGACACC
+GTAATGGAACCGCTACGCCAGCGTCTGACCGCGCTTAAAGTGGTCTTTGAACACATCACA
+ACCAAAGATGCCGCGCAGTATGTACGTGACGGCAGCTACAACCTGGCGGCGACCATTACG
+CCTCAACATTTAATGTTTAACCGTAATGATATGCTGGTTGGCGGCATTCGTCCTCACCTG
+TACTGTCTGCCGATTCTGAAACGCAATATTCACCAGCAGGCGTTACGCGACCTGGTCGCC
+AGTGGTTTTACGCGCGCCTTCCTGGGGACGGATTCAGCGCCGCATTCACGTCATCGTAAA
+GAGACCCGTTGCGGCTGCGCCGGTTGTTTCAACGCCCCCTCCGCTCTTGGCAGTTATGCC
+GCCGTGTTTGAGGAAATGAACGCGCTGGCGCACTTTGAAGCGTTCTGTTCACTGAATGGC
+CCGCAATTCTATGGCCTGCCGGTGAATACGGGGTGGGTGGAACTGGTTCGCGATGAACAA
+CAGATACCGGAAAATATCGCGCTGGCTGATGATTCGCTGGTGCCTTTTTTAGCGGGTGAA
+ACAGTACGCTGGTCAGTAAAAAAATAA
+>11111_1#11_04132
+ATGTCCGCTGGCGCGACATGCTGCTTTGTGTCAAGATTAGGGCACAGGCAACATGCTAAG
+GAACGCCATGAAAAAGTTTTTTTTGCCGCTGCGCTGGTAGTTAGCGGCCTGTTAGTGGGT
+TGTAATCAACTTACGCAATACACCATTAGCGAACAAGAAATCAATCAAGCGCTTGAAAAA
+CGGAATAATTTCTCAAAAGATATTGGTCTGCCTGGCATTGCCGACGCGCATATCGTATTG
+ACTAACCTTGCCAGCCAGATTGGTCGGGAAGAGCCTAATAAAGTCACCCTTACTGGCGAT
+GCCAGGCTGGATATGAATTCCCTGTTTGGCAGTCAAAAAGCGACGATGAAACTCAAGCTA
+AAAGCCCTGCCGGTCTTTGATAAAGAAAAAGGCGCCATCTATCTTCAGGAGATGGAAGTA
+GTAGACGCCACCGTGACGCCGGAGAAAATGCAATCAGTGCTACAAACGCTCCTGCCCTAT
+TTAAATCAGTCTTTACGTAGCTACTTTAACCAGCGGCCCGCTTACGTGTTGCGTGAGGAC
+AGTAGTAAAGGCGAAGCGTTAGCGAAGAAACTCGCGAAAGGCATTGAAGTTAAACCTGGT
+GAAATCGTTATTCCTTTCACCAATTGA
+>11111_1#11_04133
+GTGAAGCTTTATATTTACGATCATTGCCCTTTCTGCGTTAAAGCCCGCATGATTTTCGGC
+CTGAAGAACATCCCCGTTGAACTTAACGTGTTACAAAATGACGACGAGGCGACGCCCACC
+CGGATGATTGGTCAAAAGATGGTGCCCATCCTGCAAAAAGATGATAGTCGCTACCTTCCT
+GAAAGTATGGATATTGTACATTATGTCGACAACCTCGACGGCAAACCGCTGTTAACCGGG
+AAACGTAATCCAGCCATTGAAGAGTGGTTGCGCAAAGTTAACGGTTACGTTAATCAGCTA
+CTGCTGCCGCGATTTGCAAAATCCGCTTTCGATGAATTTTCTACCCCTGCGGCGCGCCAG
+TATTTTATCCGCAAAAAAGAGGCCTCATCTGGCAGTTTTGACAACCATCTTGCGCACTCT
+GCCGGACTGATTAAAAAGATCGGCGATGATTTACGTTTGCTGGATAAACTCATCGTACAG
+CCTAACGCCGTTAACGGCGAATTATCGGAAGATGATATTCATCTGTTTCCGCTTCTGCGT
+AATCTGACGCTGGTCGCCGGTATTCACTGGCCGACAAAAGTCGCGGACTATCGCGATAAT
+ATGGCTAAGCAGACGCAAATTAATTTACTCTCCTCAATGGCTATCTAA
+>11111_1#11_04134
+ATGTCGCGCGTCTCGCAGGCGAGGAACCTGGGTAAATATTTTCTTCTCATCGATAACATG
+TTAGTGGTGCTGGGTTTTTTCGTCGTCTTCCCGCTCATCTCTATTCGCTTTGTCGATCAA
+ATGGGGTGGGCTGCCGTAATGGTAGGGATCGCGCTCGGCCTGCGTCAGTTTATTCAACAA
+GGTCTGGGCATTTTTGGCGGCGCCATCGCCGATCGCTTTGGCGCGAAACCGATGATTGTC
+ACCGGTATGCTGATGCGCGCCGCAGGCTTTGCCACCATGGGTATCGCGCATGAGCCCTGG
+CTCTTGTGGTTTTCCTGCTTTCTTTCCGGTCTCGGCGGTACGCTTTTCGACCCGCCGCGT
+TCAGCGCTGGTGGTCAAATTAATTCGTCCGGAGCAACGGGGCCGCTTCTTCTCTCTGTTG
+ATGATGCAGGACAGCGCGGGCGCGGTGATTGGCGCGCTGCTGGGAAGCTGGTTGCTACAA
+TACGATTTTCGCCTGGTCTGCGCGACGGGCGCTATTTTGTTCATATTATGCGCCCTTTTC
+AACGCATGGCTGCTTCCGGCCTGGAAGCTATCAACGGCCAGAACGCCGGTGCGTGAAGGA
+ATGCGCCGCGTCATGAGCAATAAAAGGTTTGTCACCTACGTGCTGACGCTGGCGGGCTAC
+TATATGCTGGCGGTACAGGTCATGTTAATGCTGCCGATTATGGTAAACGATATCGCCGGT
+TCGCCTGCTGCCGTGAAATGGATGTACGCTATTGAGGCGTGTCTCTCGCTGACGTTGCTC
+TACCCGATTGCCCGCTGGAGCGAAAAGCGTTTTCGGCTGGAGCATCGGCTGATGGCCGGT
+TTGCTCGTCATGTCGCTGAGCATGCTCCCCATCGGGATGGTGGGCAATTTACAGCAGCTT
+TTTACGCTTATTTGCGCTTTCTACATCGGCTCGGTTATCGCCGAACCGGCGCGCGAAACG
+CTCAGCGCGTCGCCCGCGGACGCGAGGGCGCGGGGAAGCTATATGGGCTTTAGCCGTCTG
+GGATTAGCCATTGGCGGCGCGATTAGTTATATCGGCGGCGGCTGGTTGTTTGATATGGGT
+AAAGCGCTTGCGCAGCCTGAACTACCGTGGATGATGCTCGGTATTATCGGCTTTATCACC
+TTTTTGGCTTTAGGCTGGCAATTTAGTCATAAGCGCACGCCGCGCCGGATGCTGGAACCC
+GGCGCCTGA
+>11111_1#11_04135
+ATGTTTGGCTATCGCAGTAACGTGCCAAAAGTGCGCTTAACCACCGATCGTCTGGTGGTA
+CGTTTAGTGCATGAGCGTGATGCCTGGCGTCTGGCCGATTATTACGCGGAAAATCGTCAT
+TTTTTAAAACCCTGGGAACCGGTCCGTGATGAAAGTCATTGTTATCCTTCAGGATGGCAG
+GCGCGTCTGGGAATGATCGGTGAATTTCACAAACAGGGCTCCGCCTTCTATTTCGCGCTA
+CTTGATCCGGAAGAAAAAGAAATTATCGGCGTGGCGAATTTTTCCAATGTGGTGCGCGGT
+TCTTTTCATGCCTGTTATCTGGGCTATTCCATTGCGCAAGAGTGGCAGGGGCAAGGGCTG
+ATGTTTGAAGCCTTAACCGCTGCGATTCGCTATATGCAGCGCACTCAGCATATCCACCGT
+ATCATGGCGAACTATATGCCGCACAACAAACGTAGCGGCGCGTTGCTGGCGCGGCTTGGC
+TTTGAAAAAGAAGGCTATGCGAAAGATTACCTGTTGATTGATGGACAATGGCGCGACCAT
+GTCCTGACGGCGTTAACCACGCCGTTATGGACGCCGGGGCGTTGA
+>11111_1#11_04136
+ATGAAATATGAATTAACCGCCACTGAAGCGCGAGTGATTGGCTGTCTGCTGGAAAAGCAG
+GTGACAACGCCGGAACAGTATCCGCTTTCCGTCAACGGGGTGGTGACAGCCTGTAATCAG
+AAAACCAACCGTGAACCGGTGATGAACCTGACGGAACAAGAGGTACAAGAACAGCTCGAT
+AACCTGGTGAAACGCCACTTTTTGCGTACGGTCAGCGGGTTTGGCAACCGCGTCACCAAA
+TATGAACAGCGCTTCTGTAATTCCGAATTTGGCGATCTGAAACTTAGCGCGGCGGAAGTG
+GCGCTCGTCACTACGTTGCTGCTGCGCGGCGCGCAAACGCCCGGCGAGTTGCGTAGCCGG
+GCGTCGCGGATGCATGAATTCAGCGATATGGCGGAAGTTGAATCCACGCTGGAACGGCTT
+GCCAGTCGTGAGGACGGCCCGTATGTCGTCCGTCTGGCGCGTGAACCGGGTAAGCGCGAA
+AGCCGCTATATGCACCTTTTTTGCGGCGACGTCGATGAACTGTCTCTCCAGACGTCTGCG
+CCGGAAAGTGCGTCGGGCGATCTTCAGTCGCGCGTCGAAGCGCTGGAAAGCGAAGTGGCG
+GAGTTAAAGCAGCGGCTGGATTCTTTGTTAGCTCACCTGGGAGAGTAA
+>11111_1#11_04137
+GTGAGAACATTACGGATTGGCATTGTCGTGTTAGGTGGTATTGCGCAGAAGGCCTGGCTG
+CCGGTATTAACCAACACCGCCGGATGGACGTTACAGGGCGCCTGGTCTCCTTCGCGGGAT
+AAAGCCTTACGTATTTGCGAAAGCTGGCGCATACCGTATGTGGATTCGCTGGCGAATTTA
+GCGTCCGGCTGCGATGCGGTCTTCGTCCACTCCAGTACCGCAAGCCATTATGCCGTGGTC
+AGCGAACTTCTCAACGCTGGCGTCCATGTCTGCGTGGATAAACCGCTGGCGGAAAATCTA
+CGTGATGCCGAACGGCTGGTGGCGCTGGCGGCGCAAAAAAAATTGACGCTGATGGTTGGC
+TTTAATCGCCGTTTCGCGCCGCTGTACCGCGAACTGAAGACGCGCCTCGGCACTGCGGCG
+TCACTGCGTATGGATAAACATCGTACCGATAGCATCGGGCCGCATGACTTACGTTTTACT
+TTGCTCGATGACTATCTGCATGTCGTGGATACCGTTCTGTGGCTGGCGGGCGGCGAGGCG
+CGCCTTGCCAGCGGCACGTTGCTCACCAGCGAGTCCGGCGAAATGTGCTATGCGGAACAT
+CATTTTTCCGCCGACAAATTACAAATTACCACCAGTATGCACCGGCGCGCCGGAAGTCAG
+CGTGAATCGGTCCAGGCCGTCACCGATGGCGGGCTGTATGACGTGACGGATATGCGTGAA
+TGGCGCGAAGAGCGCGGGCAGGGTATTCTCATCAAACCCATTCCGGGTTGGCAAACAACG
+CTTGAGCAGCGTGGTTTTGTCGGATGCGCGCGGCATTTCATTGACTGCGTACAAAATCAG
+ACGGTTCCGGAAACGGCGGGGGAGCAGGCGATTTTGGCCCAGCGCGTCGTGGAGGCGCTG
+TGGCGGGACGCCATCAGCGAATAA
+>11111_1#11_04138
+ATGCAGGAGTTTTACGCCAGGGTCTGGAATACAAAAGAAATGAATTTATTGAAATCGCTG
+GCTGCCGTCAGCTCGATGACTATGTTTTCACGCGTGTTGGGCTTTGCCCGTGATGCGATT
+GTCGCCAGAATTTTTGGCGCAGGGATGGCGACCGACGCCTTTTTTGTGGCGTTTAAACTT
+CCCAATCTACTACGCCGGATCTTTGCCGAAGGCGCTTTTTCTCAGGCCTTTGTGCCTATC
+CTGGCGGAATATAAGAGCAAGCAGGGTGAAGAAGCGACGCGGATCTTTGTCGCTTACGTT
+TCCGGCCTGTTGACGCTGGCATTGGCCGTCGTGACGGTGGCCGGTATGCTGGCCGCCCCG
+TGGGTGATTATGGTAACCGCGCCGGGTTTTGCCGATACTGCGGATAAATTTGCGCTGACG
+ACGCAACTGCTGCGGATTACGTTTCCCTATATTCTGCTGATCTCGCTGGCTTCACTGGTT
+GGCGCCATTCTCAACACCTGGAATCGCTTCTCTATTCCCGCTTTTGCGCCGACATTTCTT
+AATATCAGTATGATCGGTTTTGCATTATTCGCCGCGCCATACTTTAATCCGCCGGTGCTG
+GCGTTAGCCTGGGCAGTCACCGTCGGCGGCGTGCTGCAACTGGTGTATCAACTTCCGTAT
+TTGAAAAAGATCGGTATGCTGGTGCTGCCGCGCATTAACTTTCACGACACCGGGGCGATG
+CGGGTGGTCAAACAGATGGGGCCGGCGATTTTGGGCGTTTCCGTCAGTCAGATCTCCCTT
+ATCATCAATACCATTTTCGCCTCGTTTCTGGCCTCCGGCTCGGTCTCATGGTTGTACTAT
+GCCGATCGGTTGATGGAGTTCCCGTCCGGCGTGCTGGGCGTGGCGTTGGGGACCATCCTG
+TTGCCGTCATTGTCGAAAAGCTTTGCCAGCGGCAATCATGATGAGTACTGCCGCCTGATG
+GACTGGGGGCTGCGTTTGTGCTTTTTACTGGCGTTGCCGAGCGCGGTAGCGCTAGGCATT
+CTGGCGAAGCCGCTGACGGTCTCGCTGTTTCAGTACGGTAAATTCACCGCCTTTGATGCG
+GCGATGACGCAGCGGGCGTTAATCGCCTATTCGGTGGGGCTGATTGGCTTGATCGTCGTA
+AAAGTGCTGGCCCCGGGCTTCTATTCTCGCCAGGATATTAAAACGCCGGTGAAAATCGCC
+ATCGTGACGTTAATCATGACGCAGTTAATGAACCTGGCGTTTATTGGACCGCTGAAACAC
+GCCGGGCTGTCGCTCTCTATTGGTCTGGCGGCATGTCTCAATGCGTCGCTGCTGTACTGG
+CAACTGCGCAAACAGAATATCTTTACGCCACAACCGGGGTGGATGTGGTTCCTGATGCGT
+CTGATCATTTCCGTACTGGTAATGGCCGCCGTGTTGTTCGGCGTGTTGCATATTATGCCG
+GAGTGGTCGCAAGGGTCGATGCTATGGCGTTTGCTGCGTTTGATGGCGGTAGTGATCGCG
+GGTATCGCGGCCTATTTCGCCGCGCTTGCCGTGCTGGGCTTTAAAGTGAAAGAGTTTGTT
+CGCCGGACGGCGTAA
+>11111_1#11_04139
+ATGACTCGTTTGTCAGAAATACTTGACCAGATGACCACCGTCCTGAATGACCTGAAGACG
+GTGATGGACGCCGAGCAACAACAGCTTTCCGTAGGCCAGATTAACGGCAGCCAGCTACAG
+CGTATTACAGAAGAAAAAAGCTCGTTGCTGGCGACGCTGGATTATCTGGAACAACAGCGC
+CGTCTGGAGCAGAACGCGCAGCGTAGCGCAAACGATGACATTGCAGAGCGCTGGCAGGCG
+ATTACCGAAAAAACGCAGCATCTGCGCGACCTCAACCAGCACAACGGCTGGCTGCTGGAA
+GGGCAAATCGAGCGTAATCAACAGGCGCTGGAGGTGCTGAAACCTCACCAGGAGCCGACC
+TTGTACGGGGCTGACGGTCAGACTTCCGTCTCTCACCGCGGCGGTAAAAAAATATCTATC
+TAA
+>11111_1#11_04140
+ATGAGCATTGACCGTACCTCACCTTTGAAACCCGTTAGCACTGTCCAGACGCGCGAAACC
+AGCGACACGCCGGTACAAAAAACGCGTCAGGAAAAAACGTCCGCCGCGACGAGCGCCAGC
+GTAACGTTAAGCGACGCGCAAGCGAAGCTTATGCAGCCAGGCGTCAGCGACATTAATATG
+GAACGCGTCGAAGCATTAAAAACGGCTATCCGTAACGGTGAGTTAAAAATGGATACGGGA
+AAAATAGCAGACTCGCTCATTCGCGAGGCGCAGAGCTACTTACAGAATAAATAA
+>11111_1#11_04141
+ATGCAAACGTTAAAACGAGGATTCGCCGTGGCGGCTTTGCTGTTCAGCCCCCTGACAATG
+GCGCAGGACATCAACGCCCAGCTGACCACGTGGTTTTCCCAGCGTCTGGCTGGCTTCAGC
+GACGAGGTGGTTGTCACGCTCCGTTCACCGCCCAATCTGCTACCGAGCTGCGAGCAGCCA
+GCCTTCAGCATGACGGGCAGCGCGAAGCTGTGGGGCAACGTCAATGTGGTGGCGCGCTGC
+GCCAATGAAAAACGTTATTTGCAGGTGAATGTGCAAGCGACCGGCAATTATGTCGCCGTA
+GCCGCGCCCGTCGCGCGCGGCGGAAAATTGACGCCGGCCAACGTCACGCTAAAACGTGGC
+AGACTGGATCAGTTACCGCCGCGGACGGTACTGGATATCCGTCAGATTCAGGATGCCGTC
+AGTTTGCGCGATCTCGCTCCCGGGCAGCCGGTACAGCTTACGATGATACGTCAGGCCTGG
+CGTGTCAAAGCGGGTCAACGAGTACAGGTCATCGCCAATGGCGAGGGGTTTAGCGTCAAT
+GCGGAAGGTCAGGCGATGAATAATGCCGCCGTCGCGCAAAATGCGCGCGTGCGCATGACA
+TCGGGTCAAATCGTGAGTGGAACCGTCGATTCTGATGGGAATATTCTTATTAACCTATAA
+>11111_1#11_04142
+ATGCTCGACAGGCTCGATGCCGCCTTACGATTTCAGCAGGAAGCGCTAAATCTGCGCGCG
+CAACGTCAGGAAATATTAGCGGCGAATATCGCCAATGCCGATACGCCGGGGTATCAGGCG
+CGCGATATTGATTTTGCCAGTGAGTTAAAAAAAGTGATGGTGCGCGGACGGGAAGAAACC
+GGCGGCGTCGCGTTGTCGTTGACTTCTTCTCGCCATATTCCCGCCCAGGCGGTCTCTTCT
+CCCGCAGTGGATCTGCTTTACCGCGTACCCGATCAGCCTTCTTTGGATGGTAACACCGTA
+GATATGGACAGGGAACGTACGCAGTTTGCGGATAACAGTCTCAAATATCAGATGGGGCTT
+ACCGTTCTGGGTAGCCAACTCAAAGGCATGATGAATGTGCTACAGGGAGGAAACTAA
+>11111_1#11_04143
+GTGGCGCTGTTAAACATTTTTGATATTGCCGGATCGGCGCTTGCCGCACAGTCCAAGCGG
+TTGAACGTTGCGGCCAGTAACCTTGCGAATGCGGATAGCGTCACCGGCCCGGACGGACAG
+CCTTATCGCGCCAAACAGGTGGTTTTTCAGGTGGACGCCGCGCCGGGTCAAGCCACTGGC
+GGGGTAAAGGTCGCCAGCGTGATTGAAAGTCAGGCACCGGAAAAGCTGGTTTATGAGCCA
+GGCAATCCGCTGGCGGACGCTAATGGTTACGTCAAAATGCCCAACGTCGATGTGGTCGGC
+GAAATGGTCAACACGATGTCAGCCTCGCGCAGCTATCAGGCAAATATCGAAGTCCTGAAT
+ACCGTAAAAAGCATGATGCTTAAAACGCTGACATTAGGCCAGTAA
+>11111_1#11_04144
+ATGTCTATTGCCGTAAATATGAATGACCCGACCAACACGGGCGTCAAAACGACGACCGGC
+AGCGGGTCGATGACCGGAAGCAACGCTGCCGATCTGCAAAGCAGTTTCCTGACCTTACTG
+GTCGCGCAATTGAAGAACCAGGACCCGACTAACCCATTACAAAATAATGAGTTAACGACA
+CAGTTGGCGCAAATCAGTACCGTGAGCGGCATTGAAAAACTGAATACGACGCTGGGGGCT
+ATTTCCGGGCAAATCGATAATAGTCAGTCCCTACAGGCGACCACGCTGATTGGACATGGC
+GTTATGGTGCCTGGCACCACAATTCTGGCGGGTAAAGGCGCGGAAGAAGGGGCCGTGACG
+TCCACGACGCCGTTTGGCGTGGAATTGCAACAGCCTGCGGACAAAGTGACGGCAACCATT
+ACCGATAAAGATGGCCGGGTGGTACGGACGCTGGAGATCGGTGAGTTGCGAGCCGGGGTA
+CACACCTTTACCTGGGATGGTAAGCAAACGGACGGAACAACGGTACCGAATGGTTCTTAC
+AACATTGCGATTACCGCCAGCAATGGCGGGACGCAACTGGTGGCGCAGCCGCTGCAATTC
+GCTCTGGTACAGGGCGTGACGAAGGGCAGTAACGGCAACCTGTTGGATCTGGGTACCTAC
+GGCACCACCACACTCGACGAAGTTCGGCAAATAATCTAA
+>11111_1#11_04145
+ATGTCTTTTTCTCAAGCGGTTAGCGGCCTGAACGCTGCGGCCACCAACCTTGATGTTATC
+GGTAATAACATCGCCAACTCCGCCACCTATGGCTTTAAGTCCGGTACGGCATCATTTGCC
+GATATGTTCGCCGGTTCCAAAGTGGGGTTGGGCGTAAAAGTGGCGGGGATTACCCAGGAT
+TTTACCGACGGTACGACAACGAACACCGGGCGCGGGCTGGATGTCGCGATTAGCCAGAAC
+GGTTTTTTCCGCCTGGTAGACAGCAACGGTTCCGTGTTCTATAGCCGCAACGGCCAGTTC
+AAACTGGACGAGAACCGTAACCTGGTCAATATGCAGGGGATGCAGTTGACCGGCTATCCG
+GCCACCGGTACGCCGCCGACCATTCAGCAGGGGGCGAATCCTGCGCCGATCACCATTCCG
+AACACGCTGATGGCGGCGAAATCGACCACCACCGCGTCAATGCAGATCAACCTGAACTCA
+ACGGACCCTGTACCGTCTAAAACGCCCTTTAGCGTGAGTGATGCGGATTCGTATAACAAA
+AAAGGCACCGTCACCGTTTATGACAGCCAGGGTAATGCCCATGACATGAACGTCTATTTT
+GTGAAAACCAAAGATAATGAATGGGCTGTGTACACCCATGACAGCAGCGATCCTGCAGCC
+ACTGCGCCAACAACGGCGTCCACTACGCTGAAATTCAATGAAAACGGGATTCTGGAGTCT
+GGCGGTACGGTGAACATCACCACCGGTACGATTAATGGCGCGACAGCGGCCACCTTCTCC
+CTCAGCTTCCTTAACTCCATGCAGCAGAACACCGGGGCTAATAACATCGTCGCCACCAAT
+CAAAACGGCTATAAGCCTGGCGACCTGGTGAGCTACCAGATTAACAATGATGGCACCGTG
+GTTGGCAACTACTCCAACGAGCAGGAGCAGGTGCTGGGGCAGATTGTGCTGGCTAACTTC
+GCCAACAACGAAGGTCTGGCATCCCAGGGCGATAACGTCTGGGCGGCGACGCAGGCCTCC
+GGGGTAGCGCTGCTGGGGACTGCCGGTTCCGGCAACTTCGGTAAGCTGACGAACGGCGCG
+CTGGAAGCCTCTAACGTGGATTTGAGTAAAGAGCTGGTGAATATGATCGTCGCGCAGCGT
+AACTACCAGTCGAATGCGCAGACCATCAAAACCCAGGACCAGATCCTCAATACGCTGGTT
+AACCTGCGCTAA
+>11111_1#11_04146
+ATGGATCACGCAATTTATACCGCCATGGGGGCGGCCAGCCAGACGCTTAACCAGCAGGCG
+GTAACGGCCAGCAACCTGGCTAATGCCTCAACGCCGGGCTTTCGCGCGCAGCTTAACGCG
+CTACGCGCGGTGCCCGTTGATGGCCTCTCTTTAGCGACGCGCACGTTGGTTACGGCGTCG
+ACGCCGGGGGCGGATATGACCCAGGGTCAGTTGGACTACACTTCCCGCCCGCTGGATGTT
+GCGTTACAGCAGGACGGCTGGCTGGTGGTGCAAGCGGCGGATGGCGCTGAAGGATATACC
+CGTAACGGGAATATCCAGGTGGGCCCGACCGGGCAGTTAACCATTCAGGGACATCCGGTT
+ATCGGCGAAGGCGGCCCGATTACCGTTCCGGAAGGGTCGGAAATCACCATTGCGGCAGAC
+GGCACGATCTCCGCGCTCAATCCCGGCGACCCGCCAAACACGGTGGCGCCCGTTGGGCGG
+CTGAAGCTGGTCAAAGCGGAAGGCAATGAGGTGCAGCGGAGCGATGACGGTTTATTCCGC
+CTTACCGCCGAGGCACAGGCTGAACGCGGGGCGGTACTGGCCGCCGACCCGTCAATTCGC
+ATTATGTCGGGCGTGCTGGAGGGCAGTAACGTCAAGCCGGTTGAAGCCATGACCGACATG
+ATCGCCAACGCACGTCGTTTTGAAATGCAGATGAAGGTTATCACCAGCGTAGATGAGAAC
+GAAGGGCGAGCTAACCAACTGCTGTCGATGAGTTAA
+>11111_1#11_04147
+ATGATCAGTTCATTATGGATCGCCAAAACCGGTCTGGACGCGCAGCAAACCAATATGGAT
+GTGATTGCCAATAACCTGGCAAACGTCAGCACCAATGGTTTTAAGCGTCAGCGCGCGGTA
+TTTGAAGATCTGTTGTATCAGACCATCCGCCAGCCGGGCGCGCAGTCGTCCGAGCAGACG
+ACGCTGCCTTCCGGGCTGCAAATCGGTACCGGCGTGCGTCCGGTCGCCACGGAGCGCCTG
+CACAGTCAGGGGAACCTGTCGCAGACCAACAACAGTAAAGATGTGGCGATTAAAGGGCAG
+GGCTTTTTCCAGGTCATGCTGCCGGACGGTACGTCTGCCTATACCCGCGACGGCTCTTTC
+CAGGTGGATCAGAATGGTCAACTGGTGACGGCGGGCGGTTTTCAGGTGCAGCCGGCAATC
+ACCATTCCGGCCAACGCGTTAAGCATCACGATTGGCCGCGACGGCGTGGTCAGCGTTACC
+CAGCAAGGGCAGGCCGCGCCGGTTCAGGTCGGGCAGCTTAACCTGACCACCTTTATGAAC
+GACACCGGTCTGGAAAGCATCGGCGAGAACCTCTATATCGAAACGCAATCGTCCGGCGCG
+CCGAACGAAAGCACGCCGGGGCTCAACGGCGCGGGGTTGTTGTATCAAGGGTATGTCGAA
+ACGTCGAACGTTAACGTGGCGGAAGAGCTGGTGAACATGATTCAGGTTCAACGCGCCTAT
+GAAATTAACAGTAAAGCAGTATCGACGACCGATCAGATGCTGCAGAAACTGACGCAACTC
+TAA
+>11111_1#11_04148
+ATGGCCCTGATGGTCGCGACGCTGACAGGATGCGCCTGGATACCCGCTAAACCGCTCGTG
+CAGGGGGCGACCACGGCGCAGCCGATACCTGGCCCGGTACCGGTGGCGAATGGCTCCATA
+TTTCAGTCTGCGCAGCCGATTAATTATGGCTATCAGCCGCTTTTTGAAGATCGTCGACCG
+CGTAATATCGGCGATACGCTCACGATTGTGTTACAGGAAAACGTCAGCGCCAGTAAAAGC
+TCGTCGGCAAATGCCAGCCGCGACGGCAAAACCAGCTTTGGTTTTGATACGGTACCGCGT
+TATCTGCAGGGATTATTCGGTAATTCCCGCGCGGATATGGAGGCCTCCGGCGGCAACTCT
+TTTAATGGTAAAGGCGGCGCGAATGCCAGCAATACCTTTAGCGGCACGCTGACCGTGACC
+GTCGATCAGGTTCTGGCCAATGGCAATTTACACGTCGTGGGGGAAAAACAGATCGCGATT
+AATCAGGGAACGGAATTCATCCGCTTCTCCGGCGTGGTAAATCCACGCACCATCAGCGGT
+AGCAACTCTGTTCCCTCGACACAGGTGGCGGATGCGCGGATTGAATATGTCGGGAACGGC
+TATATTAACGAAGCGCAAAATATGGGCTGGCTGCAACGTTTCTTCCTTAATTTGTCGCCG
+ATGTAA
+>11111_1#11_04149
+GTGTTTAAAGCTCTTGCAGGAATCGTTCTGGCACTGGTTGCCACTCTGGCGCACGCCGAG
+CGTATCCGGGATCTGACCAGTGTCCAGGGAGTACGGGAAAACTCGCTGATCGGCTACGGG
+CTGGTGGTCGGGCTGGACGGTACGGGCGACCAGACGACCCAGACGCCATTTACCACCCAG
+ACGCTGAATAACATGCTGTCACAACTGGGGATTACGGTCCCCACCGGCACCAATATGCAG
+TTGAAAAACGTGGCGGCGGTGATGGTGACGGCGTCGTATCCGCCTTTTGCGCGACAGGGA
+CAAACGATCGATGTCGTCGTTTCCTCAATGGGGAACGCTAAAAGTCTGCGTGGCGGGACG
+TTATTAATGACGCCGTTAAAAGGGGTGGACAGCCAGGTGTATGCTCTGGCGCAGGGCAAT
+ATTCTGGTCGGCGGCGCGGGCGCTTCCGCAGGCGGCAGTAGCGTGCAGGTTAACCAGCTT
+AATGGCGGGCGCATCACTAATGGCGCGATTATCGAACGCGAGTTGCCGACTCAGTTCGGC
+GCTGGCAACACCATTAATCTGCAATTGAACGACGAAGATTTTACGATGGCGCAGCAAATT
+ACCGACGCCATCAACCGCGCCCGCGGTTACGGCAGCGCCACTGCGCTTGATGCGCGAACG
+GTACAGGTACGCGTGCCCAGCGGCAACAGCTCGCAGGTGCGTTTTCTGGCGGACATTCAA
+AATATGGAAGTCAACGTGACGCCGCAGGATGCAAAAGTCGTGATCAACTCGCGTACCGGT
+TCGGTGGTCATGAATCGGGAAGTCACGCTGGATAGCTGCGCTGTGGCGCAGGGCAATTTG
+TCAGTGACAGTCAATCGCCAACTCAACGTCAACCAGCCGAATACGCCATTTGGCGGCGGG
+CAGACCGTGGTGACGCCACAGACTCAGATAGATTTGCGTCAGAGCGGCGGATCGCTACAG
+AGCGTGCGTTCCAGCGCCAATCTGAACAGCGTAGTGCGCGCGCTGAATGCGCTTGGCGCG
+ACGCCGATGGATCTGATGTCGATTTTGCAGTCCATGCAGAGCGCGGGCTGTCTACGCGCC
+AAACTGGAAATCATCTGA
+>11111_1#11_04150
+ATGATCGGAGACGGTAAATTGCTGGCCAGCGCGGCCTGGGATGCGCAATCTCTGAACGAA
+CTGAAAGCGAAAGCGGGCCAGGACCCGGCGGCGAATATCCGTCCTGTGGCCCGTCAGGTG
+GAAGGGATGTTTGTGCAGATGATGCTGAAAAGTATGCGCGAGGCTTTACCCAAAGATGGT
+TTATTCAGCAGCGATCAGACGCGTCTGTATACCAGCATGTATGACCAGCAGATCGCCCAG
+CAGATGACCGCCGGTAAGGGATTGGGGCTGGCGGATATGATGGTTAAACAGATGACGGGC
+GGGCAGACGATGCCTGCAGATGATGCGCCGCAAGTACCGCTTAAATTCTCCCTGGAGACG
+GTAAACAGCTATCAAAATCAGGCGCTGACCCAACTGGTGCGCAAAGCCATACCGAAAACG
+CCGGACAGCAGCGATGCGCCGCTCTCCGGCGACAGTAAAGACTTTCTGGCCCGGCTTTCG
+CTCCCGGCGAGGCTGGCCAGCGAACAAAGCGGGGTGCCGCATCATCTGATTCTGGCGCAG
+GCGGCGCTGGAGTCCGGCTGGGGGCAGCGGCAAATCCTGCGGGAGAATGGCGAACCCAGC
+TATAACGTATTTGGCGTGAAAGCGACCGCCAGTTGGAAAGGGCCGGTGACGGAAATCACC
+ACCACTGAATACGAAAATGGCGAAGCGAAAAAAGTGAAAGCGAAATTCCGCGTCTATAGC
+TCGTATCTGGAGGCGTTATCGGATTATGTCGCGCTGTTAACGCGTAACCCACGCTACGCT
+GCCGTGACCACTGCCGCCACGGCAGAGCAGGGCGCAGTGGCTCTGCAAAACGCCGGATAC
+GCCACTGACCCGAATTACGCGCGTAAATTGGCCAGCATGATTCAGCAGTTGAAAGCGATG
+AGTGAAAAGGTCAGCAAAACCTACAGCGCGAATCTCGACAATCTCTTTTAA
+>11111_1#11_04151
+ATGTCCAGCTTGATTAATCACGCCATGAGCGGACTTAACGCCGCGCAGGCCGCGTTAAAT
+ACGGTCAGTAATAACATCAACAATTATAACGTTGCGGGTTATACCCGGCAGACAACTATT
+CTGGCGCAGGCAAACAGTACGTTAGGGGCTGGCGGCTGGATAGGTAATGGCGTTTACGTT
+TCAGGCGTACAGCGCGAATATGATGCGTTTATCACTAATCAGCTACGCGGCGCGCAAAAC
+CAGAGCAGCGGCTTAACCACGCGCTATGAACAAATGTCGAAAATCGACAACCTGCTGGCC
+GATAAATCCAGCTCACTGTCTGGCTCGCTGCAGAGTTTTTTTACCAGCCTGCAAACGTTA
+GTCAGTAATGCGGAAGATCCTGCGGCGCGTCAGGCGCTGATTGGTAAAGCGGAAGGGCTG
+GTAAACCAGTTCAAAACCACCGATCAGTATCTGCGCGATCAGGATAAACAGGTCAATATC
+GCGATTGGCTCCAGCGTGGCGCAAATCAACAATTACGCGAAGCAGATAGCTAACCTGAAC
+GATCAAATCTCCCGTATGACGGGCGTAGGCGCGGGCGCATCGCCGAACGACCTGCTCGAT
+CAACGTGATCAGTTGGTTAGCGAGCTTAACAAGATCGTTGGCGTCGAGGTGAGTGTACAG
+GACGGCGGCACCTATAACCTGACGATGGCCAATGGCTATACGCTGGTGCAGGGGTCGACG
+GCGCGTCAGTTGGCGGCGGTTCCCTCCAGCGCCGACCCGACGCGAACGACTGTCGCTTAT
+GTCGATGAGGCCGCCGGTAACATCGAAATTCCGGAAAAGTTGCTGAACACCGGTTCGCTC
+GGCGGGCTACTGACGTTCCGTTCTCAGGATCTGGATCAGACTCGTAATACGCTGGGCCAG
+TTGGCGTTGGCGTTTGCCGATGCGTTTAACGCGCAGCATACCAAAGGTTATGACGCCGAC
+GGCAATAAAGGGAAAGACTTCTTTAGCATTGGCTCGCCGGTGGTATATAGCAACAGTAAT
+AATGCCGATAAAACGGTATCGCTAACCGCTAAGGTGGTCGACAGCACGAAGGTTCAGGCG
+ACGGATTATAAGATTGTTTTTGACGGTACAGACTGGCAGGTTACTCGCACTGCGGATAAC
+ACCACCTTCACGGCAACAAAAGATGCTGACGGAAAACTGGAGATTGACGGTCTGAAAGTG
+ACGGTAGGGACTGGCGCACAGAAAAACGACAGTTTTCTTCTCAAGCCGGTCAGCAATGCT
+ATCGTCGACATGAACGTTAAAGTGACAAATGAAGCCGAGATTGCGATGGCGTCTGAGTCA
+AAACTCGATCCTGATGTGGATACCGGCGACAGCGATAACCGCAATGGTCAGGCATTGCTG
+GACTTACAAAACAGCAATGTAGTGGGCGGCAACAAAACCTTTAACGATGCTTACGCCACG
+TTGGTCAGCGATGTGGGTAACAAAACGTCAACGCTGAAAACCAGCAGCACCACGCAGGCG
+AATGTGGTTAAACAGCTTTATAAACAGCAACAGTCGGTTTCCGGCGTTAACCTCGACGAA
+GAGTACGGCAATTTGCAGCGTTATCAGCAGTATTATCTGGCGAATGCGCAAGTATTGCAG
+ACCGCGAATGCGCTGTTTGATGCGTTATTGAATATTCGCTAA
+>11111_1#11_04152
+ATGCGTATCAGTACCCAGATGATGTACGAACAAAATATGAGCGGCATCACTAATTCTCAG
+GCCGAATGGATGAAGCTGGGCGAGCAGATGTCTACCGGTAAGCGCGTTACCAACCCATCT
+GACGATCCGATCGCCGCGTCGCAGGCGGTAGTACTCTTTCAGGCGCAGGCGCAGAATAGC
+CAGTACGCCCTGGCGCGTACGTTTGCCACCCAAAAAGTGTCGCTGGAAGAAAGCGTACTC
+AGTCAGGTGACGACGGCGATTCAAACCGCGCAGGAAAAAATCGTCTATGCCGGAAACGGC
+ACGTTAAGCGACGATGACCGCGCGTCGCTGGCGACGGATTTACAGGGGATCCGCGATCAG
+CTGATGAACCTGGCAAACAGCACTGACGGCAATGGTCGCTATATCTTTGCCGGGTATAAA
+ACGGAAGCGGCGCCATTCGACCAGGCGACAGGTGGTTATCATGGCGGCGAGAAAAGTGTT
+ACCCAGCAGGTGGATTCCGCACGCACGATGGTAATTGGCCATACGGGAGCGCAAATTTTT
+AATAGCATCACCAGCAATGCGGTGCCGGAACCGGATGGCTCGGACTCCGAAAAGAATCTG
+TTTGTCATGCTCGATACGGCAATTGCCGCGCTCAAGACCCCGGTGGAAGGCAATGACGTG
+GAAAAAGAAAAAGCCGCTGCCGCCATTGATAAAACCAATCGCGGCTTAAAAAATTCGCTT
+AATAACGTCCTGACCGTTCGTGCGGAACTGGGAACGCAACTGAGCGAACTCAGTACGCTG
+GATTCACTGGGAAGCGACCGTGCGCTGGGACAGAAGCTACAGATGAGCAACCTGGTAGAT
+GTGGACTGGAACTCGGTCATTTCCTCCTACGTCATGCAACAGGCGGCATTACAGGCGTCC
+TATAAAACGTTTACCGACATGCAGGGAATGTCGCTTTTCCAGTTGAACCGGTAA
+>22222_2#22_04112
+ATGAAACTTTTAAGAGTGGCAGCATTCGCAGCAATCGTAGTTTCTGGCAGTGCTCTGGCT
+GGCGTCGTTCCACGATGGGGCGGCGGCGGTAATCATAACGGCGGCGGCAATAGTTCCGGG
+CCGGATTCCACGTGGAGCATTTATCAGTACGGTTCCGCTAACGCTGCGCTTGCTCTGCAA
+AGCGATGCCCGTAGATCTGAAACGACCATTACCCAGAGCGGTTATGGTAACGGCGCCGAT
+GTAGGCCAGGGTGGGGATAACAGTACTATTGAACTGACTCAGAATGGTTTCAGAAACAAT
+GCCACCATCGACCGGTGGAACGCTAAAAACTCCGATATTACTGTCGGTCAATACGGCGGT
+AATAACGCCGCGCGGGTTAATCAGACCGCATCTGATTCCAGCGTAATGGTGCGTCAGGTT
+GGTTTTGGCAACAGCGCCACGGCTAACCAGTATTAA
+>22222_2#22_04141
+ATGCAAACGTTAAAACNNGGATTCGCCGTGGCGGCTTTGCTGTTCAGCCCCCTGACAATG
+GCGCAGGACATCAACGNNCAGCTGACCACGTGGTTTTCCCAGCGTCTGGCTGGCTTCAGC
+GACGAGGTGGTTGTCANNCTCCGTTCACCGCCCAATCTGCTACCGAGCTGCGAGCAGCCA
+GCCTTCAGCATGACGGNNAGCGCGAAGCTGTGGGGCAACGTCAATGTGGTGGCGCGCTGC
+GCCAATGAAAAACGTTNNTTGCAGGTGAATGTGCAAGCGACCGGCAATTATGTCGCCGTA
+GCCGCGCCCGTCGCGCNNGGCGGAAAATTGACGCCGGCCAACGTCACGCTAAAACGTGGC
+AGACTGGATCAGTTACNNCCGCGGACGGTACTGGATATCCGTCAGATTCAGGATGCCGTC
+AGTTTGCGCGATCTCGNNCCCGGGCAGCCGGTACAGCTTACGATGATACGTCAGGCCTGG
+CGTGTCAAAGCGGGTCNNCGAGTACAGGTCATCGCCAATGGCGAGGGGTTTAGCGTCAAT
+GCGGAAGGTCAGGCGANNAATAATGCCGCCGTCGCGCAAAATGCGCGCGTGCGCATGACA
+TCGGGTCAAATCGTGANNGGAACCGTCGATTCTGATGGGAATATTCTTATTAACCTATAA
diff --git a/t/data/expected_prank_input.fa.aln b/t/data/expected_prank_input.fa.aln
new file mode 100644
index 0000000..d500851
--- /dev/null
+++ b/t/data/expected_prank_input.fa.aln
@@ -0,0 +1,66 @@
+>1111#5_04506
+------------------------------------------------------------
+------------------------------------------------------------
+------------------------------------------------------------
+------------------------------------------------------------
+------------------------------------------------------------
+------------------------------------------------------------
+------------------------------------------------------------
+---------ATGGCAATCACCTTACGGGAGCTGGATGGCCTGAGCTATGAAGAGATAGCG
+GCTATCATGGATTGTCCGGTGGGGACGGTGCGTTCACGTATCTTCCGGGCGCGGGAAGCT
+ATTGATAATAAAGTTCAACCGCTTATCAGGCGT
+>1234_8#75_04759
+ATGAGCGAGCAGTTAACGGACCAGGTCCTGGTTGAACGGGTCCAGAAGGGAGATCAGAAA
+GCCTTTAACTTACTGGTAGTGCGCTACCAGCATAAAGTGGCGAGTCTGGTTTCCCGCTAT
+GTGCCATCGGGCGACGTTCCCGATGTCGTACAGGAATCATTTATTAAGGCCTATCGCGCG
+CTGGATTCTTTCCGGCGGGATAGTGCTTTTTATACCTGGTTGTATCGTATTGCGGTCAAT
+ACCGCGAAGAACTACCTGGTTGCGCAGGGGCGTCGTCCGCCTTCCAGTGATGTAGACGCG
+ATTGAAGCAGAAAACTTTGAAAGCGGCGGCGCGCTGAAAGAAATTTCGAACCCTGAGAAC
+TTAATGTTGTCAGAAGAACTGAGACAGATAGTTTTCCGAACTATTGAGTCCCTCCCGGAA
+GATTTACGTATGGCAATCACCTTACGGGAGCTGGATGGCCTGAGCTATGAAGAGATAGCG
+GCTATCATGGATTGTCCGGTGGGGACGGTGCGTTCACGTATCTTCCGGGCGCGGGAAGCT
+ATTGATAATAAAGTTCAACCGCTTATCAGGCGT
+>Salmonella_enterica_subsp_enterica_serovar_Typhimurium_DT104_v1_02853
+ATGAGCGAGCAGTTAACGGACCAGGTCCTGGTTGAACGGGTCCAGAAGGGAGATCAGAAA
+GCCTTTAACTTACTGGTAGTGCGCTACCAGCATAAAGTGGCGAGTCTGGTTTCCCGCTAT
+GTGCCATCGGGCGACGTTCCCGATGTCGTACAGGAATCATTTATTAAGGCCTATCGCGCG
+CTGGATTCTTTCCGGGGGGATAGTGCTTTTTATACCTGGTTGTATCGTATTGCGGTCAAT
+ACCGCGAAGAACTACCTGGTTGCGCAGGGGCGTCGTCCGCCTTCCAGTGATGTAGACGCG
+ATTGAAGCAGAAAACTTTGAAAGCGGCGGCGCGCTGAAAGAAATTTCGAACCCTGAGAAC
+TTAATGTTTTCAGAAGAACTGAGACAGATAGTTTTCCGAACTATTGAGTCCCTCCCGGAA
+GATTTACGTATGGCAATCACCTTACGGGAGCTGGATGGCCTGAGCTATGAAGAGATAGCG
+GCTATCATGGATTGTCCGGTGGGGACGGTGCGTTCACGTATCTTCCGGGCGCGGGAAGCT
+ATTGATAATAAAGTTCAACCGCTTATCAGGCGT
+>Salmonella_enterica_subsp_enterica_serovar_Typhimurium_SL1344_v2_02736
+ATGAGCGAGCAGTTAACGGACCAGGTCCTGGTTGAACGGGTCCAGAAGGGAGATCAGAAA
+GCCTTTAACTTACTGGTAGTGCGCTACCAGCATAAAGTGGCGAGTCTGGTTTCCCGCTAT
+GTGCCATCGGGCGACGTTCCCGATGTCGTACAGGAATCATTTATTAAGGCCTATCGCGCG
+CTGGATTCTTTCCGGGGGGATAGTGCTTTTTATACCTGGTTGTATCGTATTGCGGTCAAT
+ACCGCGAAGAACTACCTGGTTGCGCAGGGGCGTCGTCCGCCTTCCAGTGATGTAGACGCG
+ATTGAAGCAGAAAACTTTGAAAGCGGCGGCGCGCTGAAAGAAATTTCGAACCCTGAGAAC
+TTAATGTTGTCAGAAGAACTGAGACAGATAGTTTTCCGAACTATTGAGTCCCTCCCGGAA
+GATTTACGTATGGCAATCACCTTACGGGAGCTGGATGGCCTGAGCTGTGAAGAGATAGCG
+GCTATCATGGATTGTCCGGTGGGGACGGTGCGTTCACGTATCTTCCGGGCGCGGGAAGCT
+ATTGATAATAAAGTTCAACCGCTTATCAGGCGT
+>Salmonella_enterica_subsp_enterica_serovar_Typhimurium_str_D23580_v1_02783
+ATGAGCGAGCAGTTAACGGACCAGGTCCTGGTTGAACGGGTCCAGAAGGGAGATCAGAAA
+GCCTTTAACTTACTGGTAGTGCGCTACCAGCATAAAGTGGCGAGTCTGGTTTCCCGCTAT
+GTGCCATCGGGCGACGTTCCCGATGTCGTACAGGAATCATTTATTAAGGCCTATCGCGCG
+CTGGATTCTTTCCGGGGGGATAGTGCTTTTTATACCTGGTTGTATCGTATTGCGGTCAAT
+ACCGCGAAGAACTACCTGGTTGCGCAGGGGCGTCGTCCGCCTTCCAGTGATGTAGACGCG
+ATTGAAGCAGAAAACTTTGAAAGCGGCGGCGCGCTGAAAGAAATTTCGAACCCTGAGAAC
+TTAATGTTGTCAGAAGAACTGAGACAGATAGTTTTCCGAACTATTGAGTCCCTCCCGGAA
+GATTTACGTATGGCAATCACCTTACGGGAGCTGGATGGCCTGAGCTATGAAGAGATAGCG
+GCTATCATGGATTGTCCGGTGGGGACGGTGCGTTCACGTATCTTCCGGGCGCGGGAAGCT
+ATTGATAATAAAGTTCAACCGCTTATCAGGCGT
+>Salmonella_enterica_subsp_enterica_serovar_Typhimurium_str_DT2_v1_02741
+ATGAGCGAGCAGTTAACGGAC---GTCCTGGTTGAACGGGTCCAGAAGGGAGATCAGAAA
+GCCTTTAACTTACTGGTAGTGCGCTACCAGCATAAAGTGGCGAGTCTGGTTTCCCGCTAT
+GTGCCATCGGGCGACGTTCCCGATGTCGTACAGGAATCATTTATTAAGGCCTATCGCGCG
+CTGGATTCTTTCCGGGGGGATAGTGCTTTTTATACCTGGTTGTATCGTATTGCGGTCAAT
+ACCGCGAAGAACTACCTGGTTGCGCAGGGGCGTCGTCCGCCTTCCAGTGATGTAGACGCG
+ATTGAAGCAGAAAACTTTGAAAGCGGCGGCGCGCTGAAAGAAATTTCGAACCCTGAGAAC
+TTAATGTTGTCAGAAGAACTGAGACAGATAGTTTTCCGAACTATTGAGTCCCTCCCGGAA
+GATTTACGTATGGCAATCACCTTACGGGAGCTGGATGGCCTGAGCTATGAAGAGATAGCG
+GCTATCATGGATTGTCCGGTGGGGACGGTGCGTTCACGTATCTTCCGGGCGCGGGAAGCT
+ATTGATAATAAAGTTCAACCGCTTATCAGGCGT
diff --git a/t/data/expected_query_1.fna b/t/data/expected_query_1.fna
new file mode 100644
index 0000000..70ca9a0
--- /dev/null
+++ b/t/data/expected_query_1.fna
@@ -0,0 +1,252 @@
+>abc|SC|contig000001
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
+ATACCCACCACATTTGGTGGAGAACCAAAAATTAGCCGAAAAACATCATTTCTGAAGTTA
+TCGGCTAAAGTTATAAATTATATTTATTTGTACATGAACAAATAATTTACATTAATTTGT
+CATTTCTTCTTTTTCCCAATCGATTTTATATCTTTCTGAAGAACGATCTGTCCATTTATC
+TTTAGTATTGGTACCTTTCCAATTTGTTGAAGTCCAATGCAATTGGTAGTCATCACGAAC
+TCGTTCGTATATTACATCTATATTTGTTTGTTGTTTGGATGCTTTTCTATCCATAGTAAT
+AACTGTAGCGAAGTCTGGTGAAAACCCTGAAGATAATAGAGAACTTGCTTTGTTAGGATC
+AAGGAAGTTCTCTGCTGCTTTCATAGAACCATTTCTAGTTTTCATGAAAAGTTGATTGCC
+ATATACCGGGTTCCAAGAATCTCTATCATATGGTCCCCAATTTTGATTCACCATATTGTT
+AAATATCACTTTCCAGCCTACTTTTTTATCAGTTGGGCTCTCTAAAATTGTTTTGAAATC
+AGGTTGAACATATTTCAGTGTATGACCAATCGAAACATTTGCACCAATAAGGCCGCCAAT
+TTTTCCTGTATCATCACCAGTAACATTACCGTTGAATCCATAAGTTAAAGTACTCATATA
+CTCTTTTGTATCAATCGAATTTCTTGGATAGTAATCAGATATTTGAGCTACTTCATTATC
+AGGTAGTTGCAACTGTACCTTAAAGGCTGAAGGCCAGGCTAAACCACTTTTGTTAGCACC
+TTCTTCGCTATAAACTCTATATTGACCAGCAATGGTACCTTTCGTTCTAATAACTAGCAG
+TTTTTTATTGTGATTTTTATCATCGATAAAACTATAAAATACTTTTTTGTGCATGCCATT
+TTCTTTATCATAAGTGACTAAATCACCTGTTTTTACTGTAGTATTGCTTCCAATATCTGT
+AGTACCGGTTTTAATATTAATATCAGAATCTGCGGCATTAGCGACAGGATTCATTAATAT
+GGAACCTAGCAATAGTGTTGTTGTTACTGAGCTGACTATACGTGTTTTCATTTTCATCAT
+CCTTCTATTTTTTTTAACGATTTGAGGAAACAATAATCAATATGTCAATTTAGAATATTG
+CAGTTGAGACATATCAAATATTTATAATCGTTTATATTAGTATATTTAATGTAGCAACTG
+ATAAATTACTGAGTGATGATGAGTGATTATTTTAAGAATATGTTTTTAACTTTTATTTAA
+AATTTGAAAGGAAGCATTTCAATTTCGAGGGTTAGTCAAAGTTGAATAAATTCTTTATGA
+AACAAGGAAAAGACATAGCTAATTTTATTGATTAATTTCTTTAAAACTAATGATTTGTTT
+GATTTAAAAATGTAATCGATTACAATATAAAAATACAAATATCTTAGAATTAAATCAATT
+AATTAACTATTAAATAAAAATTAAATATATATTAACTACTGTAAATTAATAAATAGAAAT
+AGAGAAAAAGGGTATTAATTATGTTTGGAATTTCGTCGGGAATAATTTTTGCCATTACAT
+AGAAATATCTAATAGATAATGAAAAAGTATCGTATGTATTTTTAATATAGTGTAAAATAT
+CATATGTAAAATAAAATGTAGATTTTTAGTTAGAGGCATTATAAGAAAATTTTGAGTATA
+GGTTAGCTTTTAATTATGAATCTTATTGAAATTTGATTAATAAATATATGATAGGGGATT
+AAAATGAAACTATTTTATATCGTATTTCTTATTATTATATGGCTGAATATATTTTTAGGA
+AATGAAATTATCCATACACTGACTGTTTTAATAACAACATTGTATATTGTTAATTCAAGA
+AAGGGGATTAAAAATGACAGAGTTGAATAATATTATAAACTCTCTTCAATCTTTGTTTGA
+GTCTGAATCAGGCTATAAAATTTCGAAAAATTCAGGAGTTCCATATCAAACAGTACAAGA
+TTTAAGAAATGGGAAAACCAAACTAGAAGATGCTAGATTTAGAACGATTATTAAACTTTA
+TAGTTACTATGTCTCATTAAAAGAACATTAATCATGGGACAATAAAGTATTGCTATAATA
+ATTGAATCATTAAATGAAGGAATAGAGCCTAAGACATAATAAATCAATGTCTTAGGCTCT
+ACAATATTATATTGGTAGTAGTTGACCGAATGAAAATGACCATGTAACAAGCATTTTTGG
+GGCCCCAACACAGAAGCTGACGAAAAGTCAGCTTACAATAATGTGCAAGTTGGGGATGGG
+CCCCAACACAGAGAATTTCAAAAAGAAATTCTACAGACAATGCAAGTTGGCGGGGCCCCA
+ACATAGAGAAATTCAAAAAGAAATTCTACAGACAATGCAAGTTGGGGAGTGACAACGAAA
+TAAATTTTATAAAATACCATTTCTGTCACATTCCTACTCCCAATTCCATTTAAATATATA
+GAAAATTTCACCTATTATATACATCATACACTTTAAAAATTATCATTTAAATAATCTGAT
+TTGGAATTAAAGTGCATGAAGTATAAGTCACCTTCATATACTAATCAAAGAGGACGTCAA
+CAGTTATTTTATTAGGATTTTTAACATAAACATTTGCTAGATCTGAATGTAATCTTTTGC
+TTAAATCAATAGTGTAGTTATTACCGCCACCGGTGATCTTAAGCTTACCTTTATTACGAT
+TTTCGGTATATAATATTTTATTTTTTATTAACGCTTCTCGTGCACGGAAATCGATTTCTT
+TCAATGTTAATACTGGTTTATTGCCTTGGTATATTTTATGCGCACCAATAATCGTTTGTA
+GTTTATCTTTGTATTGCACAAAAAGATTATAAGTTTTATCAGAAGGTTTTGCGGCTGGTG
+TAACGCCACCTGTAAATGTCTCTCTATAAGACCACCATAACTGATCAGTATCTTTGTCTT
+TTAGTCCAAACACATCTACGTAACGATCTTTTAACTGATTAATATTTCCCCAACTTTCAG
+CGCCCCATAAAGATATATGTGCTGACCATGAATATCTCTTAAGTTCAACATAAATGTTTC
+CATTATCATATTGATATAGCCATTTATTTGAAAATGAAAAATGAGGCTGTGTGTAATATT
+TAATTAATTCATTGATGTTAGTTTCATCTTGACCAATGCTATAAGCTTTAGCTTCAGAGT
+AAAAACTAAATACTGGTTTTTGATTTTGAGGTAATACAGTACCTAATAGTAATAATGTTG
+TCGTTAAAATTATATTTTTCGTGATGTTCTTACTCATTAGAACATCTCCTTTCAGAGGAA
+TCATGATACGAGGAATAAGAAATTTAAATGTGAGCGAAGTCAATATAGTATTTGCGATTA
+TTTTTATTAACTCCATTATTATTGTTAGTTTGATTTTTCGAGGATAACTTCAATTTTTGC
+ATTTTGAGGTTTTTTAACATATCTATTTGCATCAGTTGATGGCAACCTTTTACTTAAATC
+TATTGTGTAGTTATTGTCTGTACCTGTTATTTTAATTTGTCCTTTATTATAAGAATTATT
+ATATAATTTTTTACTTTTAATTAATGTTTGACGAATACGAAAATCTAATTCTTTTAAAGT
+TAAAACAGGCTTATTGCCTTCATAAACTGGAAATCCGCCAGTAAACGTTTCTGCTTTATC
+TTTATATGTTACATTCAGTTTATAGTGTTTATCGTTAGATGTTGCTGCAGGAGTAACACC
+ACCAGTAAACGTTTCTTGAGATAATGCAAAAGAATCAATGGTTTCTTGGTCTTTTATGCC
+AAAAATATCAACGCTTTTATTTCTTAATTGGTTGATATTGCCCCAACTTTCAGGTCCATA
+AACTTGAATATGACTATACCAAGAAAACTGTAACAACGTTGCATGAATCGTACCGTTATC
+TTTTTGCCATAACGTACTGTTAGAGAAGGTTAAATATTTTTGCGAGTAATATTTAGTTAA
+CTCATTAACGTTAGTTTCGTTTTGATTTATATAATAAGCTTTCGCTTCAGATGAAGAATT
+GATAGGTGTATTAGGAAATTGTGTAAATGCTGTACCTAATAGTAACAATGTTGTTGATAA
+AATAATTTTTTTCGTGATGTTATTGTTCATTCGAATTTCTCCTTTGAGTATTGTTGGAAT
+GTTTAATTATAAAAAGGGGTTAATTAGATAATTGAAATTATCCGCATTTACAAAAGGTAA
+TAGGTTAGTTAGATTTTTCGAGTATGACTTCAATTTGTGCATTTTTAGGATTTTTAACAT
+AACGGTTTGTGTCAGTTAATTTTAACTTTTTACTTAAATCAATCGTGTAATTATTTCCAT
+CAGCAGTTATCTTAATTTGACCTTTATTAAATTCTCCGTTATATAACTTTTTATTCTTTA
+TTAATGTTTGACGAATACGGAAATCTAATTCTTTTAAAGTTAATACTGGTTTATTTCCTT
+TGTAAAATTCATGTCCACCGATGATAGTTTGTTGTTTATCACTATATTTTAAAAATAGTC
+TATAAGGTTTATCAGATGAAGTAGCTGCTGGCGTAACACCACCAGTAAATGTTTCATCAT
+AAGTCCAGTAACCTTCAACTGTGTCCTCATCTTTAGTTCCAAATATATCAACGTATTTAT
+TTCTTAACTGATTAATGTTTCCCCAACTCTCGGATCCAAACACTTGAATATGACTATACC
+AAACCCACGTTTGCAATGTTGCATGAATGCTACCATTGGGCTTTTGCCATAGCCATTTTC
+CAGATAATGAAAAATGCGGCTGAGTGTAATATTTGATTAACTCATTGATATTAGTCTCGT
+TTTCACTGATATTATAGGCTTTTGCTTCAGATGAAAAACTGATTGGTGTTTTAGGAAGTT
+GTGTTGATGTGGTTCCTAAAAGTAACAATGCTGTTGATAAAACTAATTTATTCATGATGT
+TCTTTTTCATATGAAAATCTCCTTTGCGTGAATTACCCAAAGTATATAAGCTATTACACC
+GATTCGGAATTAAATAAAAGCTAAAACTATGTTAAATAAACTTAAACAGTTAGTAGTGTT
+ATTTAAGCAAAACTTATCATTTTTAAGTTTTGGACAGAAACAGTACTTAATAAAGTAGGC
+GGGAGTTATATATTAAAAACGACACGTTACAATTATTCTCTAATCAATTGCATTAAATTG
+TTTGATAATTGAATTTTCTAACTACTTGAAAAATAGTTATACTTTAAATGTAGTACTTAT
+TTTAATTATTTCCTACTACTTAAATTTAATATTAATAAAATGTTCATTTAATTATTGATA
+AAATATTACAAATTTTAATAGTAGGTTGTGTTTATTTTGTATGCGCTTACAATTTAGGTG
+TAACTAAAATAAAAGGAGTTGTTATTAATGAAAAATTTACGAAACAGAAGTTTTTTAACT
+TTATTAGACTTTTCACGACAAGAGGTAGAATTCTTATTAACACTCTCCGAGGATTTAAAA
+CGTGCTAAATATATTGGCACTGAAAAGCCTATGTTAAAAAATAAAAATATTGCACTGTTA
+TTTGAAAAAGATTCTACAAGAACGCGATGTGCATTTGAAGTTGCAGCGCATGATCAAGGT
+GCAAATGTAACTTATTTAGGCCCAACTGGATCACAAATGGGTAAAAAAGAAACAACTAAA
+GATACTGCACGTGTGCTTGGTGGAATGTATGATGGCATTGAATACCGTGGTTTTTCACAA
+AGAACAGTAGAAACTTTAGCTGAAAATTCAGGCGTACCAGTGTGGAATGGTTTAACTGAT
+GAAGATCATCCTACTCAAGTTCTTGCTGATTTCTTAACAGCAAAAGAAGTCTTAAAAAAA
+GATTATGCAGATATTAACTTTACATATGTTGGAGATGGTCGTAATAACGTTGCAAATGCA
+TTAATGCAAGGTGCTGCCATTATGGGTATGAACTTCCATTTAGTTTGTCCAAAAGAATTA
+AATCCAACAGATGAATTATTAAATCGCTGTAAAAATATTGCCGCTGAAAATGGTGGCAAC
+ATATTAATCACAGATGATATTGACCAAGGTGTAAAAGGTTCGGATGTAATTTACACTGAT
+GTTTGGGTATCAATGGGTGAACCTGATGAAGTATGGAAAGAACGACTTGAATTATTGAAA
+CCATATCAAGTAAATAAAGAAATGATGGATAAAACTGGTAATCCAAATGTTATTTTTGAG
+CATTGCTTACCATCTTTCCATAATGCTGATACGAAAATTGGTCAACAAATTTTTGAAAAA
+TATGGTATTCGAGAAATGGAAGTTACAGATGAAGTATTCGAAAGTAAAGCTTCAGTTGTA
+TTCCAAGAAGCTGAGAACAGAATGCATACAATCAAAGCAGTCATGGTTGCTACATTGGGT
+GAATTTTAAATGATATAAGGAAGTGAATATGATGGCGAAAATAGTAGTAGCATTAGGTGG
+TAATGCTTTAGGAAAATCACCTCAAGAACAACTCGAGCTTGTTAAAAATACTGCGAAATC
+ATTAGTAGGATTAATAACAAAAGGACATGAGATTGTTATTAGTCATGGTAATGGACCACA
+GGTTGGAAGCATTAATTTGGGACTTAACTATGCTGCAGAACATAACCAAGGTCCGGCATT
+TCCATTTGCTGAATGTGGCGCAATGAGTCAAGCTTACATCGGCTATCAATTACAAGAAAG
+CTTACAAAATGAATTGCATTCTATTGGAATGGATAAACAAGTGGTAACACTAGTGACACA
+AGTTGAAGTTGATGAAAATGATCCGGCATTTAACAATCCTTCAAAACCAATTGGGTTATT
+TTACAACAAAGAAGAAGCTGAACAAATTCAAAAAGAAAAAGGATTTATATTTGTTGAAGA
+TGCTGGAAGAGGATATAGACGCGTTGTTCCTTCACCACAACCCATCTCTATTATTGAATT
+AGAGAGTATTAAAACACTTATTAAAAATGATACACTCGTTATTGCTGCTGGTGGTGGAGG
+TATACCAGTAATTAGAGAGCAACATGATGGTTTTAAAGGTATTGATGCAGTTATAGACAA
+AGATAAAACAAGTGCGTTGTTGGGTGCTAATATTCAATGCGATCAATTGATTATTTTAAC
+AGCAATTGATTATGTATATATTAATTTTAACACTGAAAACCAACAGCCTTTGAAAACAAC
+AAATGTTGATGAATTAAAACGATATATAGACGAAAATCAATTTGCAAAAGGAAGTATGTT
+ACCAAAAATTGAAGCAGCCATATCATTTATTGAAAACAATCCAAAAGGAAGTGTGCTTAT
+AACATCATTAAATGAATTAGATGCTGCCTTAGAGGGTAAAGTAGGTACTGTGATTAAAAA
+GTAATTGAATTGAAACGCTTTTCAATTACTATATGTCAAATGCATGATTTTTATTATTTA
+TGTGCACCCCCTGAAAATAATGCCTCTATTTTGATGCGGGGTGCACTTTCTTAATTTATA
+TTTATAAAATCTTTAAGGTAGAAATGCTAGGTTAAATGTCGAAGGAGATGAAACCGTGGA
+AAATACAATTAATGAAAGTGAAAAGAAAAAACGATTTAAATTAAAAATGCCAGGTGCATT
+TATGATTTTATTCATTTTAACGGTTGTTGCAGTTATAGCAACATGGGTTATTCCTGCTGG
+TGCATATTCTAAACTTTCTTACGAACCTTCATCCCAAGAACTAAAGATAGTTAACCCTCA
+TAACCAAGTGAAAAAGGTTCCGGGTACGCAACAGGAACTAGACAAAATGGGGGTTAAAAT
+TAAGATTGAACAATTTAAATCAGGTGCAATTAATAAGCCAGTATCAATTCCGAATACTTA
+TGAAAGATTAAAGCAACATCCAGCTGGACCAGAACAAATAACAAGTAGCATGGTTGAAGG
+TACGATAGAAGCGGTCGATATCATGGTATTCATTCTTGTACTAGGGGGACTTATTGGCGT
+AGTTCAAGCCAGTGGTTCTTTTGAATCGGGATTGTTAGCTTTAACGAAGAAAACAAAAGG
+GCATGAATTTATGCTAATTGTGTTTGTATCAATACTAATGATTATCGGCGGGACGTTATG
+TGGTATTGAAGAAGAAGCTGTAGCATTCTATCCGATTTTAGTCCCTATATTTATAGCGTT
+AGGATACGATTCTATCGTTTCAGTTGGTGCCATATTCCTTGCCAGCTCTGTCGGTAGTAC
+ATTTTCAACTATTAACCCGTTCTCGGTTGTAATTGCCTCTAATGCCGCTGGTACAACTTT
+TACGGATGGCTTGTATTGGAGAATAGGTGCTTGTATTGTCGGTGCGATTTTTGTTATTAG
+TTATTTATATTGGTACTGTAAAAAAATTAAAAACGATCCTAAAGCGTCATATTCTTATGA
+AGACAAAGATGCTTTTGAACAGCAATGGTCTGTATTAAAAGATGACGATAGTGCCCATTT
+TACTTTGCGTAAGAAGATAATCCTTACATTATTTGTACTACCATTTCCAATTATGGTATG
+GGGAGTTATGACGCAAGGTTGGTGGTTCCCAGTTATGGCTTCAGCATTTTTAATATTTAC
+AATTATAATAATGTTTATTGCTGGGACAGGTAAATCTGGATTGGGAGAAAAAGGAACTGT
+AGATGCATTTGTCAATGGTGCATCAAGTTTAGTAGGTGTATCTTTAATTATTGGTTTAGC
+TCGAGGTATTAATTTAGTGTTGAATGAAGGTATGATTTCAGATACAATCTTACACTTTTC
+ATCATCTTTAGTTCAACATATGAGTGGACCATTATTTATCATCGTATTACTATTTATTTT
+CTTCTGTTTAGGTTTTATCGTGCCATCATCTTCTGGATTAGCGGTATTATCAATGCCTAT
+CTTTGCACCACTAGCTGATACAGTAGGTATACCAAGATTCGTCATCGTTACGACATATCA
+ATTTGGTCAATATGCGATGTTATTCTTAGCGCCGACTGGACTTGTTATGGCCACACTACA
+AATGTTAAACATGCGATATTCACATTGGTTCCGATTTGTATGGCCGGTAGTTGCTTTTGT
+ATTGATTTTCGGTGGCGGAGTACTAATTACGCAAGTACTAATTTATTCATAATTTGAAAT
+GCTATATTATAAAAATACTAATTGGGTTTTATGCATCTCGTAGGTTTGTAGAAATACTAA
+ACTAAGCGAGGTGCATTATTATTTTTGATTAAGAAAATAATGACGGTAATGATAACACTA
+GTAAGTAATTGATACAATGCTCTATTTAATAATGATATTTTTAAAATTTGTTTTTAATGT
+AATGTTAGATCTATGGTATATTATATTTATCGTGGTAAATATGTATTTGCTGTAAACAGT
+TTTTGTAACACATGACACATATGGTTGTGAAAATAGCATATATAAAGGATGGCTATAAAT
+GACACATTTGACAAAGGTTTTAGATACACTAACTGGAATATGCGTAGTATTATTATTTAG
+TAAATATTTTGTGGCGTATGCAAATATGGTGTTTGATTGGAATTTAAGATGGTATTTGCT
+AGAAAACATACCACATTTGCCAATTATATTATTTATTCTGATGTTTATTTTCGGAGTACC
+TTCTGAAATGATAAAAGATAGGCAAAGGAAAAATAACGGTGTTTAATTTATCGATATTTA
+GAGGTGATAAAATTTGTCAACTATTACAAAGACTAAAATAAAAATCTTTATTAATTATTT
+TATTGGTATATTAGCCTTGGCGTTTGCTGCTTATATATTATTTAAATAAAGGTTAGAGTG
+AAACGTGTTTATGAACTAGACGTTCTAGTATAGTTACTACAGCTTTAGTCAGAAGGTATC
+ATTGATAAGATCATATTAAATCAAAGAGGCATTGATATACACTAAAAAGAGGCAAGATTA
+CCTGCCTCTTTTTTAGTTATTAAATATGCGTGTTAATTCTTGGTAATAGTGTTACTGAGA
+CGCATTACGAAGAAATTTATCTTGATTTTCCTTTTTTAAAAAGAAGTGAAGATATCCTAT
+AAAGACTCTAAGTACTATTACAGTGGCTAATAACACTTCGATAAACAAAAGACCTTTCCA
+AATATCTGGAAACATAAGTACAGGCAAACTGTTCTTTAAAGCAGTTGCTGAGATTACTAA
+AGGGAATGTGAAAGCTGAAAATACGGGCGAAAAAGGTTCTTTTAGTAATTTAGGCAATTG
+TATAATGATATAAAAATAAAATATTTGAGCTAATATTAAAAATATAATTACGATAAAAGC
+ATTCGCCTTAGGAAAGGCTATAACATATGCTGCAGCGACTAAAGAAAATGGTGCACAAAT
+TGTCGATGTGTTCGGTTTGATTGACGTCTGCAATGGAAATGCTTTTAATCGCTTGAAAAC
+AATAGGTAAGACAATACAAGTAGCTACAAAGCCATATATTACTGTTAATTGACCTATGAA
+AAAACATCCGCTAACGGGTGCCGTCAATCCTGCGATAGCAATACCAATAAAAAGTACAGT
+CCACGAAGGATAAACATTTTCAAGTGAAAAATCTTTTAAATATTTTATTGAAAAAATAAT
+CATATGCGTCATAATTCCCACAAGGCATAAAATCCAAATAGGCGTTATTAAGCTATTGAT
+AAAAGTTATGTTACTAAAAAATGTATTTAAATAAGTAGTACCTAAAAAGCCAGACATGAA
+AAATGTTGTGAACACTGATGAAACTAGAGGACTGTTTAATTGTTCTTTCACATTATTAAA
+ATATTTGATCATAGTACATAAAAGGTGAATCCAAATCAAGAAAGCAAAGATTCCGCAAAC
+AGCGTTTAAAGTAAGAGATAAGTCTTTTAATAGATTACCCAGGCCTAATAATCCTAAGAC
+TAGTCCTGACGTTACTAGAGGTGCTTTTTGAAGTCTCATGATTTACAACCTTTCTTATGT
+GATTTTCTTCACTAATTATATCATGATAGCTATGGCCAATTAATAAGAAGAGTGTGTACT
+ATTACGTTATTAGAGTATGTATATTGGATTGATAGACACATAATTGACATTTAAATCTCA
+AAATTAATGATATTTGAGGTATGCTTTGCAACCTAAATATTGGAATATGTGGAAAAGTAA
+TTATTTAATTTAAATGATGATTGAAGATTTACAAGGGGGTGTACAAAATGAGAAATCAAA
+TTCAAAAACTATTAGACAGTGATTTGAGCAGTTTACATATATCGAAACAAACAGGAGTTC
+CACAAAGCACAATACACAGAATGAGAAAAAAAGAAAGATCATTAGACAATATGTCATTGA
+AAAACGCTGAACTACTTTATAAATTTGCCAATAGTATATTTAGCAATGAAAATTAAGAAG
+AATAATTAGTGAGTTAAATAATTAAAAAACCACGTCTCGATGGACGTGGTTATTTTTTTA
+AATGTATTTAATTATAGGATTTCGGGCCCCTGAAAAGTCCCTAAAATTTTGAATAGTATC
+AAAATCTATAGGAATAATATAATAATAAAAATCTCTACGCATGCAAATGGTGAGTGTTAA
+AAATCTTGGTGTAGTGTTGGTGTAGTTCAGGTGCAGTATAGATGAAATTTGAGCACAAAA
+TTACTTAATTAAAAATGTATAAACAAGTGTCAGACGCGTGTCAATTGTGTGTCAAAAAAT
+TCTATGACGAATAAGCATGCTTGTTTTAATTACTGTATTTTCGGGGCTTATGCGGGGGAC
+GTTTTGGTGACGCATCATACTATATTACTGAAATTCAAAACAAAAAGAGCCCCGTAATCA
+CGGAACTCTTTTGTTTGGTAATGCGTATAAAAATACCTATAAACGTCCTGGGAGGGATTC
+GAACCCCCGACCGATGGCTTAGAAGGCCATTGCTCTATCCAGCTGAGCTACCAGGACACG
+TTTAACAACACAAGAATTATTATATCTAAATGAACTTAAATTAGCAATACCTTGTAAATA
+AAAAATGTTTATATTTTTCACTATTATAGAGCTATTTATCTAAAAAGGTTCAATAAGACT
+TAAATGCGAATTCAGGCAACTTAATTGTGTTAAATACAGTTTTGAATGCCTAACTGTATT
+TCTTTTCTCTTTAAAATACAGTTAAGTACATTATAAGATGTTGTGCGGATAAACAAACTA
+ATTGCATCAAATTTATTTTAAAATAACAACAACAAAACGTTAAGCGAATAACATTTCGGT
+GATTTAAAAGCTACGCACGTTTTTGTTATCTTCAAATTTAAATTTTAAGGAGTGTTTTCA
+ATGGAAGGTTTATTTAACGCAATTAAAGATACCGTAACTGCAGCAATTAATAATGATGGC
+GCAAAATTAGGCACAAGCATTGTGAGCATCGTTGAAAATGGCGTAGGTTTATTAGGTAAA
+TTATTCGGATTCTAATTTCAATATGTTATGTAAGTAATCAGTATTATTTCAAAGGTGAGG
+GAGAGATTTAAATGACTGGACTAGCAGAAGCAATCGCAAATACTGTGCAAGCTGCACAAC
+AACATGATAGTGTGAAATTAGGCACAAGTATCGTAGACATCGTTGCTAACGGTGTGGGTT
+TACTAGGTAAATTATTTGGATTCTAATATAATAACTAATATTCTTTAAAATAAACTGGGT
+GAGCATACTTTAATGTTATGCACTCAGTTTATTTTATTTGCAGAAATTTGAGCCTCTGTT
+AAGATTTAGATACATAGACAATATAGGAGATGGGGAAATTGGGATATAAAAATATTTTGA
+TAGACTTTGATGATACAATTGTTGATTTTTATGATGCAGAAGAATGGGCGTTTCACTATA
+TGGCGAATGTTTTTAATCATAAAGCAACAAAGGATGATTTTTTAACATTTAAAAAAATCA
+ATCACCAACATTGGGAAGCTTTTCAACAAAATAAATTAACGAAGTCTGAAGTATTATCAG
+AACGATTTGTGAATTACTTCAAACATCATCAAATGGAAGTTGATGGGCATCGTGCAGATG
+TGTTATTTAGAAATGGATTAGCAGAAGCTAAAGTTAAATACTTTGATCAAACATTAGAAA
+CAATTGTCGAATTATCGAAAAGACATGATTTATATATTGTTACTAATGGTGTAACCGAAA
+CGCAAAAGAGAAGGTTAAATCAGACGCCGTTGCATAAATATATTAAAAAGATATTTATAT
+CTGAGGAAACAGGATATCAAAAACCTAATCCGGAATTTTTTAATTATGTTTTTAATGATA
+TTGGTGAGGATGAAAGACAGCACTCGATTATAGTTGGAGATTCTTTAACATCTGACATTC
+TAGGTGGAATCAATGCGGGTATAGCTACTTGCTGGTTTAATTTTAGAGGATTTGATCATA
+ATCCAGGAATTATACCTGATTATGAAATTAATTCATGGAAACAACTAAATGATATTGTAC
+GTTAAGACAAATAATTTGAAAATGATTTATATTAGCTTAAGAAAGTAATTGTAAAAACGA
+CACTACGAAAAGATGCATTTTCATGCTCGTAGTGTCGAATATTATTATCTTATGGTTTCC
+ACAATAAGACATCATGTCCCTCTATATTTTTAGCTTCCACATCTGTAAATCCATGATGTA
+AAAAGAAATCCTTAGAATCATTTCTGCCAATGGCTTTAATTGGCATATTGAAACTCTTTG
+CAAAATCAATCAATTCTGAAGCGTACCCTCTGTTTTGATATTTTGGTAATACTTCTAACT
+TCCATAATAATATATAATCTTCAAAATCTGGGAAGTAGATTTCTTCGACATCACCTTTTT
+TTAGTAATGCCATTCTAGCTCCTAATTGATCTCCGACAAATATGCCATAAAATGGTGAAT
+CTGAACTTGCATCAATCATTTGACCGTTTAACTCATTGACCATGTATAAGTCTTTGTTGC
+CAAACGCTCTAAAGTTTTCGAATAATTCGTCAGTTTTGTAATTAATTTCAAGACGTTTGA
+TTTCACTCATATTTATCTACCCCTTATTTGTTTACTACTATTATTATACATTAAACCACT
+TGTGTTTTTCATTGATTTGAAAATGTAAAACAATGAACATTATAAATTTTCCATGATTAA
+ATTGATTTTCAAGCCGTAAAATTGTCAATCACCGGTATAGACTTTATACTATAGTTTGTA
+ATCGCGTACTTAAGGAGAAAAAACATGGACTGTAAAGTAGTTAGTTTAAATGAAAAAGAT
+CAGTTTATACCAAAAATAAAGAGCAGTGACCCTGTAATAACAGGATTATTTCAATATGAT
+GCAGCTCAACAAACTAGTTTTGAAAAAAGGATGTCTAAAGAAAATAATGGAAGAGAAGCG
+GCATTAGCGAATGTTATTCGTGAATATATGAGTGATTTAAAGCTTTCAAATGAACAAGAA
+TTAAACATACAACATTTAGCTAATGGTTCAAAAGTTGTGATTGGTGGACAACAAGCAGGG
+CTTTTCGGGGGACCATTGTATACATTCCATAAAATATTTTCAATCATTACTTTATCTAAG
+GAATTAACGGATACACATAAGCAACAAGTAGTACCAGTTTTTTGGATTGCAGGAGAAGAT
+CATGATTTCGATGAAGTGAATCATACATTTGTTTATAACGAAAATCATGGGTCGCTGCAT
+AAGGTTAAATATCATACAATGGAGATGCCAGAGACGACAGTCTCTAGATATTATCCTGAT
+AAGGCTGAGTTGAAACAAACTTTAAAAACGATGTTCATTCATATGAAAGAAACTGTTCAT
+ACACAAGGTCTACTGGAGATTTGTGACAGAATTATTGACCAATATGACTCGTGGACTGAT
+ATGTTTAAAGCACTACTGCATGAAACATTTAAAGCATATGGCGTTCTATTTATAGATGCG
+CAGTTTGAGCCGTTAAGAAAAATGGAAGCGCCTATGTTTAAAAAGATTTTGAAAAAACAT
+CAGTTGCTTGATGATGCTTTTAGAGCAACACAACAACGTACTCAAAATCAAGGCTTGAAT
+GCGATGATACAAACAGATACAAATGTTCATTTATTCTTACATGATGAAAATATGCGCCAA
+TTAGTTTCGTATGATGGTAAGCATTTTAAATTAAATAAAACAGATAAGACATATATAAAG
diff --git a/t/data/expected_query_2.fna b/t/data/expected_query_2.fna
new file mode 100644
index 0000000..70ca9a0
--- /dev/null
+++ b/t/data/expected_query_2.fna
@@ -0,0 +1,252 @@
+>abc|SC|contig000001
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
+ATACCCACCACATTTGGTGGAGAACCAAAAATTAGCCGAAAAACATCATTTCTGAAGTTA
+TCGGCTAAAGTTATAAATTATATTTATTTGTACATGAACAAATAATTTACATTAATTTGT
+CATTTCTTCTTTTTCCCAATCGATTTTATATCTTTCTGAAGAACGATCTGTCCATTTATC
+TTTAGTATTGGTACCTTTCCAATTTGTTGAAGTCCAATGCAATTGGTAGTCATCACGAAC
+TCGTTCGTATATTACATCTATATTTGTTTGTTGTTTGGATGCTTTTCTATCCATAGTAAT
+AACTGTAGCGAAGTCTGGTGAAAACCCTGAAGATAATAGAGAACTTGCTTTGTTAGGATC
+AAGGAAGTTCTCTGCTGCTTTCATAGAACCATTTCTAGTTTTCATGAAAAGTTGATTGCC
+ATATACCGGGTTCCAAGAATCTCTATCATATGGTCCCCAATTTTGATTCACCATATTGTT
+AAATATCACTTTCCAGCCTACTTTTTTATCAGTTGGGCTCTCTAAAATTGTTTTGAAATC
+AGGTTGAACATATTTCAGTGTATGACCAATCGAAACATTTGCACCAATAAGGCCGCCAAT
+TTTTCCTGTATCATCACCAGTAACATTACCGTTGAATCCATAAGTTAAAGTACTCATATA
+CTCTTTTGTATCAATCGAATTTCTTGGATAGTAATCAGATATTTGAGCTACTTCATTATC
+AGGTAGTTGCAACTGTACCTTAAAGGCTGAAGGCCAGGCTAAACCACTTTTGTTAGCACC
+TTCTTCGCTATAAACTCTATATTGACCAGCAATGGTACCTTTCGTTCTAATAACTAGCAG
+TTTTTTATTGTGATTTTTATCATCGATAAAACTATAAAATACTTTTTTGTGCATGCCATT
+TTCTTTATCATAAGTGACTAAATCACCTGTTTTTACTGTAGTATTGCTTCCAATATCTGT
+AGTACCGGTTTTAATATTAATATCAGAATCTGCGGCATTAGCGACAGGATTCATTAATAT
+GGAACCTAGCAATAGTGTTGTTGTTACTGAGCTGACTATACGTGTTTTCATTTTCATCAT
+CCTTCTATTTTTTTTAACGATTTGAGGAAACAATAATCAATATGTCAATTTAGAATATTG
+CAGTTGAGACATATCAAATATTTATAATCGTTTATATTAGTATATTTAATGTAGCAACTG
+ATAAATTACTGAGTGATGATGAGTGATTATTTTAAGAATATGTTTTTAACTTTTATTTAA
+AATTTGAAAGGAAGCATTTCAATTTCGAGGGTTAGTCAAAGTTGAATAAATTCTTTATGA
+AACAAGGAAAAGACATAGCTAATTTTATTGATTAATTTCTTTAAAACTAATGATTTGTTT
+GATTTAAAAATGTAATCGATTACAATATAAAAATACAAATATCTTAGAATTAAATCAATT
+AATTAACTATTAAATAAAAATTAAATATATATTAACTACTGTAAATTAATAAATAGAAAT
+AGAGAAAAAGGGTATTAATTATGTTTGGAATTTCGTCGGGAATAATTTTTGCCATTACAT
+AGAAATATCTAATAGATAATGAAAAAGTATCGTATGTATTTTTAATATAGTGTAAAATAT
+CATATGTAAAATAAAATGTAGATTTTTAGTTAGAGGCATTATAAGAAAATTTTGAGTATA
+GGTTAGCTTTTAATTATGAATCTTATTGAAATTTGATTAATAAATATATGATAGGGGATT
+AAAATGAAACTATTTTATATCGTATTTCTTATTATTATATGGCTGAATATATTTTTAGGA
+AATGAAATTATCCATACACTGACTGTTTTAATAACAACATTGTATATTGTTAATTCAAGA
+AAGGGGATTAAAAATGACAGAGTTGAATAATATTATAAACTCTCTTCAATCTTTGTTTGA
+GTCTGAATCAGGCTATAAAATTTCGAAAAATTCAGGAGTTCCATATCAAACAGTACAAGA
+TTTAAGAAATGGGAAAACCAAACTAGAAGATGCTAGATTTAGAACGATTATTAAACTTTA
+TAGTTACTATGTCTCATTAAAAGAACATTAATCATGGGACAATAAAGTATTGCTATAATA
+ATTGAATCATTAAATGAAGGAATAGAGCCTAAGACATAATAAATCAATGTCTTAGGCTCT
+ACAATATTATATTGGTAGTAGTTGACCGAATGAAAATGACCATGTAACAAGCATTTTTGG
+GGCCCCAACACAGAAGCTGACGAAAAGTCAGCTTACAATAATGTGCAAGTTGGGGATGGG
+CCCCAACACAGAGAATTTCAAAAAGAAATTCTACAGACAATGCAAGTTGGCGGGGCCCCA
+ACATAGAGAAATTCAAAAAGAAATTCTACAGACAATGCAAGTTGGGGAGTGACAACGAAA
+TAAATTTTATAAAATACCATTTCTGTCACATTCCTACTCCCAATTCCATTTAAATATATA
+GAAAATTTCACCTATTATATACATCATACACTTTAAAAATTATCATTTAAATAATCTGAT
+TTGGAATTAAAGTGCATGAAGTATAAGTCACCTTCATATACTAATCAAAGAGGACGTCAA
+CAGTTATTTTATTAGGATTTTTAACATAAACATTTGCTAGATCTGAATGTAATCTTTTGC
+TTAAATCAATAGTGTAGTTATTACCGCCACCGGTGATCTTAAGCTTACCTTTATTACGAT
+TTTCGGTATATAATATTTTATTTTTTATTAACGCTTCTCGTGCACGGAAATCGATTTCTT
+TCAATGTTAATACTGGTTTATTGCCTTGGTATATTTTATGCGCACCAATAATCGTTTGTA
+GTTTATCTTTGTATTGCACAAAAAGATTATAAGTTTTATCAGAAGGTTTTGCGGCTGGTG
+TAACGCCACCTGTAAATGTCTCTCTATAAGACCACCATAACTGATCAGTATCTTTGTCTT
+TTAGTCCAAACACATCTACGTAACGATCTTTTAACTGATTAATATTTCCCCAACTTTCAG
+CGCCCCATAAAGATATATGTGCTGACCATGAATATCTCTTAAGTTCAACATAAATGTTTC
+CATTATCATATTGATATAGCCATTTATTTGAAAATGAAAAATGAGGCTGTGTGTAATATT
+TAATTAATTCATTGATGTTAGTTTCATCTTGACCAATGCTATAAGCTTTAGCTTCAGAGT
+AAAAACTAAATACTGGTTTTTGATTTTGAGGTAATACAGTACCTAATAGTAATAATGTTG
+TCGTTAAAATTATATTTTTCGTGATGTTCTTACTCATTAGAACATCTCCTTTCAGAGGAA
+TCATGATACGAGGAATAAGAAATTTAAATGTGAGCGAAGTCAATATAGTATTTGCGATTA
+TTTTTATTAACTCCATTATTATTGTTAGTTTGATTTTTCGAGGATAACTTCAATTTTTGC
+ATTTTGAGGTTTTTTAACATATCTATTTGCATCAGTTGATGGCAACCTTTTACTTAAATC
+TATTGTGTAGTTATTGTCTGTACCTGTTATTTTAATTTGTCCTTTATTATAAGAATTATT
+ATATAATTTTTTACTTTTAATTAATGTTTGACGAATACGAAAATCTAATTCTTTTAAAGT
+TAAAACAGGCTTATTGCCTTCATAAACTGGAAATCCGCCAGTAAACGTTTCTGCTTTATC
+TTTATATGTTACATTCAGTTTATAGTGTTTATCGTTAGATGTTGCTGCAGGAGTAACACC
+ACCAGTAAACGTTTCTTGAGATAATGCAAAAGAATCAATGGTTTCTTGGTCTTTTATGCC
+AAAAATATCAACGCTTTTATTTCTTAATTGGTTGATATTGCCCCAACTTTCAGGTCCATA
+AACTTGAATATGACTATACCAAGAAAACTGTAACAACGTTGCATGAATCGTACCGTTATC
+TTTTTGCCATAACGTACTGTTAGAGAAGGTTAAATATTTTTGCGAGTAATATTTAGTTAA
+CTCATTAACGTTAGTTTCGTTTTGATTTATATAATAAGCTTTCGCTTCAGATGAAGAATT
+GATAGGTGTATTAGGAAATTGTGTAAATGCTGTACCTAATAGTAACAATGTTGTTGATAA
+AATAATTTTTTTCGTGATGTTATTGTTCATTCGAATTTCTCCTTTGAGTATTGTTGGAAT
+GTTTAATTATAAAAAGGGGTTAATTAGATAATTGAAATTATCCGCATTTACAAAAGGTAA
+TAGGTTAGTTAGATTTTTCGAGTATGACTTCAATTTGTGCATTTTTAGGATTTTTAACAT
+AACGGTTTGTGTCAGTTAATTTTAACTTTTTACTTAAATCAATCGTGTAATTATTTCCAT
+CAGCAGTTATCTTAATTTGACCTTTATTAAATTCTCCGTTATATAACTTTTTATTCTTTA
+TTAATGTTTGACGAATACGGAAATCTAATTCTTTTAAAGTTAATACTGGTTTATTTCCTT
+TGTAAAATTCATGTCCACCGATGATAGTTTGTTGTTTATCACTATATTTTAAAAATAGTC
+TATAAGGTTTATCAGATGAAGTAGCTGCTGGCGTAACACCACCAGTAAATGTTTCATCAT
+AAGTCCAGTAACCTTCAACTGTGTCCTCATCTTTAGTTCCAAATATATCAACGTATTTAT
+TTCTTAACTGATTAATGTTTCCCCAACTCTCGGATCCAAACACTTGAATATGACTATACC
+AAACCCACGTTTGCAATGTTGCATGAATGCTACCATTGGGCTTTTGCCATAGCCATTTTC
+CAGATAATGAAAAATGCGGCTGAGTGTAATATTTGATTAACTCATTGATATTAGTCTCGT
+TTTCACTGATATTATAGGCTTTTGCTTCAGATGAAAAACTGATTGGTGTTTTAGGAAGTT
+GTGTTGATGTGGTTCCTAAAAGTAACAATGCTGTTGATAAAACTAATTTATTCATGATGT
+TCTTTTTCATATGAAAATCTCCTTTGCGTGAATTACCCAAAGTATATAAGCTATTACACC
+GATTCGGAATTAAATAAAAGCTAAAACTATGTTAAATAAACTTAAACAGTTAGTAGTGTT
+ATTTAAGCAAAACTTATCATTTTTAAGTTTTGGACAGAAACAGTACTTAATAAAGTAGGC
+GGGAGTTATATATTAAAAACGACACGTTACAATTATTCTCTAATCAATTGCATTAAATTG
+TTTGATAATTGAATTTTCTAACTACTTGAAAAATAGTTATACTTTAAATGTAGTACTTAT
+TTTAATTATTTCCTACTACTTAAATTTAATATTAATAAAATGTTCATTTAATTATTGATA
+AAATATTACAAATTTTAATAGTAGGTTGTGTTTATTTTGTATGCGCTTACAATTTAGGTG
+TAACTAAAATAAAAGGAGTTGTTATTAATGAAAAATTTACGAAACAGAAGTTTTTTAACT
+TTATTAGACTTTTCACGACAAGAGGTAGAATTCTTATTAACACTCTCCGAGGATTTAAAA
+CGTGCTAAATATATTGGCACTGAAAAGCCTATGTTAAAAAATAAAAATATTGCACTGTTA
+TTTGAAAAAGATTCTACAAGAACGCGATGTGCATTTGAAGTTGCAGCGCATGATCAAGGT
+GCAAATGTAACTTATTTAGGCCCAACTGGATCACAAATGGGTAAAAAAGAAACAACTAAA
+GATACTGCACGTGTGCTTGGTGGAATGTATGATGGCATTGAATACCGTGGTTTTTCACAA
+AGAACAGTAGAAACTTTAGCTGAAAATTCAGGCGTACCAGTGTGGAATGGTTTAACTGAT
+GAAGATCATCCTACTCAAGTTCTTGCTGATTTCTTAACAGCAAAAGAAGTCTTAAAAAAA
+GATTATGCAGATATTAACTTTACATATGTTGGAGATGGTCGTAATAACGTTGCAAATGCA
+TTAATGCAAGGTGCTGCCATTATGGGTATGAACTTCCATTTAGTTTGTCCAAAAGAATTA
+AATCCAACAGATGAATTATTAAATCGCTGTAAAAATATTGCCGCTGAAAATGGTGGCAAC
+ATATTAATCACAGATGATATTGACCAAGGTGTAAAAGGTTCGGATGTAATTTACACTGAT
+GTTTGGGTATCAATGGGTGAACCTGATGAAGTATGGAAAGAACGACTTGAATTATTGAAA
+CCATATCAAGTAAATAAAGAAATGATGGATAAAACTGGTAATCCAAATGTTATTTTTGAG
+CATTGCTTACCATCTTTCCATAATGCTGATACGAAAATTGGTCAACAAATTTTTGAAAAA
+TATGGTATTCGAGAAATGGAAGTTACAGATGAAGTATTCGAAAGTAAAGCTTCAGTTGTA
+TTCCAAGAAGCTGAGAACAGAATGCATACAATCAAAGCAGTCATGGTTGCTACATTGGGT
+GAATTTTAAATGATATAAGGAAGTGAATATGATGGCGAAAATAGTAGTAGCATTAGGTGG
+TAATGCTTTAGGAAAATCACCTCAAGAACAACTCGAGCTTGTTAAAAATACTGCGAAATC
+ATTAGTAGGATTAATAACAAAAGGACATGAGATTGTTATTAGTCATGGTAATGGACCACA
+GGTTGGAAGCATTAATTTGGGACTTAACTATGCTGCAGAACATAACCAAGGTCCGGCATT
+TCCATTTGCTGAATGTGGCGCAATGAGTCAAGCTTACATCGGCTATCAATTACAAGAAAG
+CTTACAAAATGAATTGCATTCTATTGGAATGGATAAACAAGTGGTAACACTAGTGACACA
+AGTTGAAGTTGATGAAAATGATCCGGCATTTAACAATCCTTCAAAACCAATTGGGTTATT
+TTACAACAAAGAAGAAGCTGAACAAATTCAAAAAGAAAAAGGATTTATATTTGTTGAAGA
+TGCTGGAAGAGGATATAGACGCGTTGTTCCTTCACCACAACCCATCTCTATTATTGAATT
+AGAGAGTATTAAAACACTTATTAAAAATGATACACTCGTTATTGCTGCTGGTGGTGGAGG
+TATACCAGTAATTAGAGAGCAACATGATGGTTTTAAAGGTATTGATGCAGTTATAGACAA
+AGATAAAACAAGTGCGTTGTTGGGTGCTAATATTCAATGCGATCAATTGATTATTTTAAC
+AGCAATTGATTATGTATATATTAATTTTAACACTGAAAACCAACAGCCTTTGAAAACAAC
+AAATGTTGATGAATTAAAACGATATATAGACGAAAATCAATTTGCAAAAGGAAGTATGTT
+ACCAAAAATTGAAGCAGCCATATCATTTATTGAAAACAATCCAAAAGGAAGTGTGCTTAT
+AACATCATTAAATGAATTAGATGCTGCCTTAGAGGGTAAAGTAGGTACTGTGATTAAAAA
+GTAATTGAATTGAAACGCTTTTCAATTACTATATGTCAAATGCATGATTTTTATTATTTA
+TGTGCACCCCCTGAAAATAATGCCTCTATTTTGATGCGGGGTGCACTTTCTTAATTTATA
+TTTATAAAATCTTTAAGGTAGAAATGCTAGGTTAAATGTCGAAGGAGATGAAACCGTGGA
+AAATACAATTAATGAAAGTGAAAAGAAAAAACGATTTAAATTAAAAATGCCAGGTGCATT
+TATGATTTTATTCATTTTAACGGTTGTTGCAGTTATAGCAACATGGGTTATTCCTGCTGG
+TGCATATTCTAAACTTTCTTACGAACCTTCATCCCAAGAACTAAAGATAGTTAACCCTCA
+TAACCAAGTGAAAAAGGTTCCGGGTACGCAACAGGAACTAGACAAAATGGGGGTTAAAAT
+TAAGATTGAACAATTTAAATCAGGTGCAATTAATAAGCCAGTATCAATTCCGAATACTTA
+TGAAAGATTAAAGCAACATCCAGCTGGACCAGAACAAATAACAAGTAGCATGGTTGAAGG
+TACGATAGAAGCGGTCGATATCATGGTATTCATTCTTGTACTAGGGGGACTTATTGGCGT
+AGTTCAAGCCAGTGGTTCTTTTGAATCGGGATTGTTAGCTTTAACGAAGAAAACAAAAGG
+GCATGAATTTATGCTAATTGTGTTTGTATCAATACTAATGATTATCGGCGGGACGTTATG
+TGGTATTGAAGAAGAAGCTGTAGCATTCTATCCGATTTTAGTCCCTATATTTATAGCGTT
+AGGATACGATTCTATCGTTTCAGTTGGTGCCATATTCCTTGCCAGCTCTGTCGGTAGTAC
+ATTTTCAACTATTAACCCGTTCTCGGTTGTAATTGCCTCTAATGCCGCTGGTACAACTTT
+TACGGATGGCTTGTATTGGAGAATAGGTGCTTGTATTGTCGGTGCGATTTTTGTTATTAG
+TTATTTATATTGGTACTGTAAAAAAATTAAAAACGATCCTAAAGCGTCATATTCTTATGA
+AGACAAAGATGCTTTTGAACAGCAATGGTCTGTATTAAAAGATGACGATAGTGCCCATTT
+TACTTTGCGTAAGAAGATAATCCTTACATTATTTGTACTACCATTTCCAATTATGGTATG
+GGGAGTTATGACGCAAGGTTGGTGGTTCCCAGTTATGGCTTCAGCATTTTTAATATTTAC
+AATTATAATAATGTTTATTGCTGGGACAGGTAAATCTGGATTGGGAGAAAAAGGAACTGT
+AGATGCATTTGTCAATGGTGCATCAAGTTTAGTAGGTGTATCTTTAATTATTGGTTTAGC
+TCGAGGTATTAATTTAGTGTTGAATGAAGGTATGATTTCAGATACAATCTTACACTTTTC
+ATCATCTTTAGTTCAACATATGAGTGGACCATTATTTATCATCGTATTACTATTTATTTT
+CTTCTGTTTAGGTTTTATCGTGCCATCATCTTCTGGATTAGCGGTATTATCAATGCCTAT
+CTTTGCACCACTAGCTGATACAGTAGGTATACCAAGATTCGTCATCGTTACGACATATCA
+ATTTGGTCAATATGCGATGTTATTCTTAGCGCCGACTGGACTTGTTATGGCCACACTACA
+AATGTTAAACATGCGATATTCACATTGGTTCCGATTTGTATGGCCGGTAGTTGCTTTTGT
+ATTGATTTTCGGTGGCGGAGTACTAATTACGCAAGTACTAATTTATTCATAATTTGAAAT
+GCTATATTATAAAAATACTAATTGGGTTTTATGCATCTCGTAGGTTTGTAGAAATACTAA
+ACTAAGCGAGGTGCATTATTATTTTTGATTAAGAAAATAATGACGGTAATGATAACACTA
+GTAAGTAATTGATACAATGCTCTATTTAATAATGATATTTTTAAAATTTGTTTTTAATGT
+AATGTTAGATCTATGGTATATTATATTTATCGTGGTAAATATGTATTTGCTGTAAACAGT
+TTTTGTAACACATGACACATATGGTTGTGAAAATAGCATATATAAAGGATGGCTATAAAT
+GACACATTTGACAAAGGTTTTAGATACACTAACTGGAATATGCGTAGTATTATTATTTAG
+TAAATATTTTGTGGCGTATGCAAATATGGTGTTTGATTGGAATTTAAGATGGTATTTGCT
+AGAAAACATACCACATTTGCCAATTATATTATTTATTCTGATGTTTATTTTCGGAGTACC
+TTCTGAAATGATAAAAGATAGGCAAAGGAAAAATAACGGTGTTTAATTTATCGATATTTA
+GAGGTGATAAAATTTGTCAACTATTACAAAGACTAAAATAAAAATCTTTATTAATTATTT
+TATTGGTATATTAGCCTTGGCGTTTGCTGCTTATATATTATTTAAATAAAGGTTAGAGTG
+AAACGTGTTTATGAACTAGACGTTCTAGTATAGTTACTACAGCTTTAGTCAGAAGGTATC
+ATTGATAAGATCATATTAAATCAAAGAGGCATTGATATACACTAAAAAGAGGCAAGATTA
+CCTGCCTCTTTTTTAGTTATTAAATATGCGTGTTAATTCTTGGTAATAGTGTTACTGAGA
+CGCATTACGAAGAAATTTATCTTGATTTTCCTTTTTTAAAAAGAAGTGAAGATATCCTAT
+AAAGACTCTAAGTACTATTACAGTGGCTAATAACACTTCGATAAACAAAAGACCTTTCCA
+AATATCTGGAAACATAAGTACAGGCAAACTGTTCTTTAAAGCAGTTGCTGAGATTACTAA
+AGGGAATGTGAAAGCTGAAAATACGGGCGAAAAAGGTTCTTTTAGTAATTTAGGCAATTG
+TATAATGATATAAAAATAAAATATTTGAGCTAATATTAAAAATATAATTACGATAAAAGC
+ATTCGCCTTAGGAAAGGCTATAACATATGCTGCAGCGACTAAAGAAAATGGTGCACAAAT
+TGTCGATGTGTTCGGTTTGATTGACGTCTGCAATGGAAATGCTTTTAATCGCTTGAAAAC
+AATAGGTAAGACAATACAAGTAGCTACAAAGCCATATATTACTGTTAATTGACCTATGAA
+AAAACATCCGCTAACGGGTGCCGTCAATCCTGCGATAGCAATACCAATAAAAAGTACAGT
+CCACGAAGGATAAACATTTTCAAGTGAAAAATCTTTTAAATATTTTATTGAAAAAATAAT
+CATATGCGTCATAATTCCCACAAGGCATAAAATCCAAATAGGCGTTATTAAGCTATTGAT
+AAAAGTTATGTTACTAAAAAATGTATTTAAATAAGTAGTACCTAAAAAGCCAGACATGAA
+AAATGTTGTGAACACTGATGAAACTAGAGGACTGTTTAATTGTTCTTTCACATTATTAAA
+ATATTTGATCATAGTACATAAAAGGTGAATCCAAATCAAGAAAGCAAAGATTCCGCAAAC
+AGCGTTTAAAGTAAGAGATAAGTCTTTTAATAGATTACCCAGGCCTAATAATCCTAAGAC
+TAGTCCTGACGTTACTAGAGGTGCTTTTTGAAGTCTCATGATTTACAACCTTTCTTATGT
+GATTTTCTTCACTAATTATATCATGATAGCTATGGCCAATTAATAAGAAGAGTGTGTACT
+ATTACGTTATTAGAGTATGTATATTGGATTGATAGACACATAATTGACATTTAAATCTCA
+AAATTAATGATATTTGAGGTATGCTTTGCAACCTAAATATTGGAATATGTGGAAAAGTAA
+TTATTTAATTTAAATGATGATTGAAGATTTACAAGGGGGTGTACAAAATGAGAAATCAAA
+TTCAAAAACTATTAGACAGTGATTTGAGCAGTTTACATATATCGAAACAAACAGGAGTTC
+CACAAAGCACAATACACAGAATGAGAAAAAAAGAAAGATCATTAGACAATATGTCATTGA
+AAAACGCTGAACTACTTTATAAATTTGCCAATAGTATATTTAGCAATGAAAATTAAGAAG
+AATAATTAGTGAGTTAAATAATTAAAAAACCACGTCTCGATGGACGTGGTTATTTTTTTA
+AATGTATTTAATTATAGGATTTCGGGCCCCTGAAAAGTCCCTAAAATTTTGAATAGTATC
+AAAATCTATAGGAATAATATAATAATAAAAATCTCTACGCATGCAAATGGTGAGTGTTAA
+AAATCTTGGTGTAGTGTTGGTGTAGTTCAGGTGCAGTATAGATGAAATTTGAGCACAAAA
+TTACTTAATTAAAAATGTATAAACAAGTGTCAGACGCGTGTCAATTGTGTGTCAAAAAAT
+TCTATGACGAATAAGCATGCTTGTTTTAATTACTGTATTTTCGGGGCTTATGCGGGGGAC
+GTTTTGGTGACGCATCATACTATATTACTGAAATTCAAAACAAAAAGAGCCCCGTAATCA
+CGGAACTCTTTTGTTTGGTAATGCGTATAAAAATACCTATAAACGTCCTGGGAGGGATTC
+GAACCCCCGACCGATGGCTTAGAAGGCCATTGCTCTATCCAGCTGAGCTACCAGGACACG
+TTTAACAACACAAGAATTATTATATCTAAATGAACTTAAATTAGCAATACCTTGTAAATA
+AAAAATGTTTATATTTTTCACTATTATAGAGCTATTTATCTAAAAAGGTTCAATAAGACT
+TAAATGCGAATTCAGGCAACTTAATTGTGTTAAATACAGTTTTGAATGCCTAACTGTATT
+TCTTTTCTCTTTAAAATACAGTTAAGTACATTATAAGATGTTGTGCGGATAAACAAACTA
+ATTGCATCAAATTTATTTTAAAATAACAACAACAAAACGTTAAGCGAATAACATTTCGGT
+GATTTAAAAGCTACGCACGTTTTTGTTATCTTCAAATTTAAATTTTAAGGAGTGTTTTCA
+ATGGAAGGTTTATTTAACGCAATTAAAGATACCGTAACTGCAGCAATTAATAATGATGGC
+GCAAAATTAGGCACAAGCATTGTGAGCATCGTTGAAAATGGCGTAGGTTTATTAGGTAAA
+TTATTCGGATTCTAATTTCAATATGTTATGTAAGTAATCAGTATTATTTCAAAGGTGAGG
+GAGAGATTTAAATGACTGGACTAGCAGAAGCAATCGCAAATACTGTGCAAGCTGCACAAC
+AACATGATAGTGTGAAATTAGGCACAAGTATCGTAGACATCGTTGCTAACGGTGTGGGTT
+TACTAGGTAAATTATTTGGATTCTAATATAATAACTAATATTCTTTAAAATAAACTGGGT
+GAGCATACTTTAATGTTATGCACTCAGTTTATTTTATTTGCAGAAATTTGAGCCTCTGTT
+AAGATTTAGATACATAGACAATATAGGAGATGGGGAAATTGGGATATAAAAATATTTTGA
+TAGACTTTGATGATACAATTGTTGATTTTTATGATGCAGAAGAATGGGCGTTTCACTATA
+TGGCGAATGTTTTTAATCATAAAGCAACAAAGGATGATTTTTTAACATTTAAAAAAATCA
+ATCACCAACATTGGGAAGCTTTTCAACAAAATAAATTAACGAAGTCTGAAGTATTATCAG
+AACGATTTGTGAATTACTTCAAACATCATCAAATGGAAGTTGATGGGCATCGTGCAGATG
+TGTTATTTAGAAATGGATTAGCAGAAGCTAAAGTTAAATACTTTGATCAAACATTAGAAA
+CAATTGTCGAATTATCGAAAAGACATGATTTATATATTGTTACTAATGGTGTAACCGAAA
+CGCAAAAGAGAAGGTTAAATCAGACGCCGTTGCATAAATATATTAAAAAGATATTTATAT
+CTGAGGAAACAGGATATCAAAAACCTAATCCGGAATTTTTTAATTATGTTTTTAATGATA
+TTGGTGAGGATGAAAGACAGCACTCGATTATAGTTGGAGATTCTTTAACATCTGACATTC
+TAGGTGGAATCAATGCGGGTATAGCTACTTGCTGGTTTAATTTTAGAGGATTTGATCATA
+ATCCAGGAATTATACCTGATTATGAAATTAATTCATGGAAACAACTAAATGATATTGTAC
+GTTAAGACAAATAATTTGAAAATGATTTATATTAGCTTAAGAAAGTAATTGTAAAAACGA
+CACTACGAAAAGATGCATTTTCATGCTCGTAGTGTCGAATATTATTATCTTATGGTTTCC
+ACAATAAGACATCATGTCCCTCTATATTTTTAGCTTCCACATCTGTAAATCCATGATGTA
+AAAAGAAATCCTTAGAATCATTTCTGCCAATGGCTTTAATTGGCATATTGAAACTCTTTG
+CAAAATCAATCAATTCTGAAGCGTACCCTCTGTTTTGATATTTTGGTAATACTTCTAACT
+TCCATAATAATATATAATCTTCAAAATCTGGGAAGTAGATTTCTTCGACATCACCTTTTT
+TTAGTAATGCCATTCTAGCTCCTAATTGATCTCCGACAAATATGCCATAAAATGGTGAAT
+CTGAACTTGCATCAATCATTTGACCGTTTAACTCATTGACCATGTATAAGTCTTTGTTGC
+CAAACGCTCTAAAGTTTTCGAATAATTCGTCAGTTTTGTAATTAATTTCAAGACGTTTGA
+TTTCACTCATATTTATCTACCCCTTATTTGTTTACTACTATTATTATACATTAAACCACT
+TGTGTTTTTCATTGATTTGAAAATGTAAAACAATGAACATTATAAATTTTCCATGATTAA
+ATTGATTTTCAAGCCGTAAAATTGTCAATCACCGGTATAGACTTTATACTATAGTTTGTA
+ATCGCGTACTTAAGGAGAAAAAACATGGACTGTAAAGTAGTTAGTTTAAATGAAAAAGAT
+CAGTTTATACCAAAAATAAAGAGCAGTGACCCTGTAATAACAGGATTATTTCAATATGAT
+GCAGCTCAACAAACTAGTTTTGAAAAAAGGATGTCTAAAGAAAATAATGGAAGAGAAGCG
+GCATTAGCGAATGTTATTCGTGAATATATGAGTGATTTAAAGCTTTCAAATGAACAAGAA
+TTAAACATACAACATTTAGCTAATGGTTCAAAAGTTGTGATTGGTGGACAACAAGCAGGG
+CTTTTCGGGGGACCATTGTATACATTCCATAAAATATTTTCAATCATTACTTTATCTAAG
+GAATTAACGGATACACATAAGCAACAAGTAGTACCAGTTTTTTGGATTGCAGGAGAAGAT
+CATGATTTCGATGAAGTGAATCATACATTTGTTTATAACGAAAATCATGGGTCGCTGCAT
+AAGGTTAAATATCATACAATGGAGATGCCAGAGACGACAGTCTCTAGATATTATCCTGAT
+AAGGCTGAGTTGAAACAAACTTTAAAAACGATGTTCATTCATATGAAAGAAACTGTTCAT
+ACACAAGGTCTACTGGAGATTTGTGACAGAATTATTGACCAATATGACTCGTGGACTGAT
+ATGTTTAAAGCACTACTGCATGAAACATTTAAAGCATATGGCGTTCTATTTATAGATGCG
+CAGTTTGAGCCGTTAAGAAAAATGGAAGCGCCTATGTTTAAAAAGATTTTGAAAAAACAT
+CAGTTGCTTGATGATGCTTTTAGAGCAACACAACAACGTACTCAAAATCAAGGCTTGAAT
+GCGATGATACAAACAGATACAAATGTTCATTTATTCTTACATGATGAAAATATGCGCCAA
+TTAGTTTCGTATGATGGTAAGCATTTTAAATTAAATAAAACAGATAAGACATATATAAAG
diff --git a/t/data/expected_real_data_core_gene_alignment.aln b/t/data/expected_real_data_core_gene_alignment.aln
new file mode 100644
index 0000000..f2bc3fa
--- /dev/null
+++ b/t/data/expected_real_data_core_gene_alignment.aln
@@ -0,0 +1,2168 @@
+>real_data_1
+ATGAAAAAATCATTACTCGCTGTTGCTGTGGCAGGGGCTGTTTTGTTGTCATCCGCCGTA
+CAGGCGCAGACAACGCCGGAAGGTTATCAATTACAACAGGTGCTGATGATGAGCCGCCAT
+AATCTGCGGGCGCCGCTGGCGAATAATGGCAACGTACTGGCGCAGTCGACGCCGAACGCC
+TGGCCGGCGTGGGACGTTCCCGGCGGGCAACTGACGACGAAAGGCGGCGTGCTGGAAGTC
+TATATGGGACACTACACACGTGAATGGCTGGTCGCGCAGGGGCTGATACCGTCGGGAGAA
+TGTCCGGCGCCCGACACGGTATATGCCTATGCGAATAGTTTGCAGCGCACCGTCGCCACC
+GCGCAATTTTTCATTACCAGCGCTTTCCCCGGCTGTGATATTCCTGTTCATCATCAGGAA
+AAAATGGGCACTATGGACCCTACCTTCAATCCGGTGATTACCGATGATTCCGCCGCGTTC
+CGGCAACAGGCCGTACAGGCGATGGAAAAGGCGCGTAGTCAGCTACATCTTGATGAGAGT
+TATAAACTGCTTGAGCAGATAACGCATTATCAGGACTCGCCGTCCTGCAAAGAGAAGCAT
+CAGTGTTCGCTAATCGACGCGAAAGATACCTTCAGCGCGAACTATCAGCAAGAGCCTGGC
+GTGCAGGGGCCGCTGAAAGTAGGGAACTCGCTGGTGGATGCGTTTACCCTGCAATATTAC
+GAAGGCTTTCCGATGGATCAGGTCGCTTGGGGCGGGATCCACACCGATCGGCAGTGGAAG
+GTGCTGTCAAAACTGAAAAACGGCTACCAGGACAGCCTGTTTACCTCACCCACGGTGGCG
+CGCAATGTCGCTGCGCCGCTGGTAAAATATATCGATAAGGTGCTGGTTGCCGAGCGCGTT
+AGCGCGCCGAAGGTTACCGTGCTGGTGGGGCATGATTCCAATATCGCGTCGCTGCTGACG
+GCGCTGGATTTTAAACCCTATCAGCTCCATGACCAGTATGAGAGAACGCCGATTGGTGGT
+CAGCTTGTCTTCCAACGCTGGCATGACGGTAACGCTAACCGGGATTTGATGAAAATCGAG
+TATGTCTACCAGAGCGCCCGGCAGTTACGTAATGCGGAAGCGTTAACGCTCAAATCGCCT
+GCGCAAAGGGTAACGCTGGAACTGAAAGGATGTCCGGTGGATGCGAACGGCTTCTGTCCG
+CTGGATAAGTTCGATAACGTCATGAACACTGCTGCAAAATAGATGGAAAAGAATAATGAA
+GTCATTCAGACCCATCCGCTTGTAGGATGGGACATCAGCACCGTCGATAGCTATGATGCG
+CTGATGCTGCGTTTACACTACCAGACCCCAAATCGTCCGGAACCGGAAGGGACTGAAGTT
+GGTCAAACGCTCTGGTTAACGACAGATGTAGCCAGGCAATTTATTTCAATATTAGAAGCC
+GGCATCGCCAAAATAGAATCAGGCGATTACCAGGAAAACGAGTATCGTCACCATTAGATG
+GAACTTAAGGATTATTACGCCATTATGGGCGTGAAACCGACGGACGATCTCAAGACGATT
+AAGACCGCCTATCGCCGACTGGCCCGCAAGTACCATCCAGATGTCAGCAAAGAACCCGAT
+GCCGAAGCCCGTTTCAAAGAGGTTGCTGAAGCATGGGAAGTGCTGAGTGATGAGCAACGG
+CGCGCCGAGTATGACCAGTTATGGCAACACCGTAACGATCCACAATTTAATCGCCAGTTC
+CAGCAACACGAAGGCCAGCCGTATAACGCCGAAGATTTTGATGATATTTTCTCGTCTATT
+TTTGGTCAGCACGGTCGTCATTCGCACCACCGCCACGCCGCACGCGGTCATGATATCGAA
+ATTGAAGTGGCGGTATTCCTGGAAGAAACGCTGGAAGAGCACCAGCGTACGATTAGCTAT
+TCCGTCCCCGTTTATAACGCGTTCGGCCTGGTGGAGCGGGAAATTCCCAAAACATTGAAT
+GTGAAAATCCCGGCTGGCGTCAGCAACGGGCAACGAATCAGACTGAAAGGCCAGGGCACG
+CCGGGGGAAAACGGCGGACCTAATGGCGATTTATGGCTCGTTATCCATATTGCCCCGCAT
+CCGCTCTTTGATATCGTCAATCAGGATCTGGAAGTCGTCCTTCCGCTTGCCCCATGGGAG
+GCGGCGCTCGGCGCTAAGGTGTCTGTGCCAACGCTTAAAGAGCGTATTTTGCTGACCATT
+CCCCCCGGCAGCCAGGCAGGTCAGCGGCTGCGTATCAAAGGAAAAGGATTAGCCAGTAAA
+AAGCACACTGGCGATCTCTATGCCATCATCAAAATCGTTATGCCGCCGAAACCTGACGAG
+AAAACAGCTGCCCTGTGGCAACAACTGGCGGACGCGCAGTCGTCCTTTGACCCACGCCAG
+CAATGGGGGAAAGCATAAATGGCTAACATCACTGTCACCTTTACCATCACCGAATTTTGT
+TTGCACACCGGCGTGACGGAAGAGGAGCTAAACGAAATCGTCGGACTTGGCGTAATTGAG
+CCTTACGAAGACGATAACGCCGACTGGCAATTCGACGATCGCGCAGCGAGCGTGGTACAA
+CGCGCGCTACGCTTACGCGAGGAGCTGGCGCTCGACTGGCCAGGGATCGCGGTCGCGTTA
+ACGCTGCTGGAAGAGAATTCACGGCTGCGCGAAGAAAACCGGTTACTGCTGCAACGCCTT
+TCTCGCTTTATCTCGCATCCCTAAATGTCATCTTGTTGGAGATTTACGGATTCGCTAACA
+AGCCTATGGCATACTGCGTTGATGAAGATTTTATTGATTGAAGATAACCAGAAAACCATT
+GAGTGGGTACGTCAGGGACTCACGGAGGCAGGCTATGTGGTTGATTATGCCTGTGATGGA
+CGAGACGGATTACACCTAGCCCTTCAGGAACATTATTCATTGATTATTCTTGATATTATG
+CTGCCGGGGCTTGATGGATGGCAGGTTTTACGCGCGTTGCGCACTGCATATCAGCCCCCT
+GTTATTTGCCTGACGGCGCGCGACTCGGTTGAGGATCGCGTCAAAGGTCTTGAGGCGGGC
+GCTAATGATTACCTTGTTAAGCCTTTTTCCTTCGCCGAACTGCTGGCCCGGGTGAGAGCT
+CAACTCAGACAGCATGTCCCGGTCTTTACCCGACTGACGATCAATGGTCTGGACATGGAT
+GCCACAAAGCAATCGGTGTTACGAAATGGCAAACCGATTTCCCTGACCCGCAAAGAATTC
+CTGCTCCTCTGGTTACTGGCGTCCCGGGCAGGGGAAATCGTGCCCCGAACCGCGATCGCC
+AGCGAAGTTTGGGGAATTAACTTTGATAGTGAAACCAACACCGTTGATGTCGCGATTCGT
+CGGCTGCGCGCCAAAGTAGACGATCCATTTGAAAAGAAGCTCATTATGACCGTCCAGGGG
+ATGGGTTATCGATTACAGGCGGAAACGTCGCAGAATGGTTAAATGAAAAACAAATTGTTA
+TTTATGATGTTGACAATACTGGGTGCGCCTGGGATTGCAACCGCGACAAATTATGATCTG
+GCTCGTTCAGAGTATAATTTTGCGGTAAATGAATTAAGCAAGTCTTCATTTAATCAGGCG
+GCCATTATTGGTCAAGTCGGCACGGATAATAGTGCCAGAGTACGCCAGGAAGGATCAAAA
+CTATTGTCCGTTATTTCACAAGAAGGAGAAAATAATCGGGCGAAAGTCGACCAGGCAGGG
+AATTATAACTTTGCGTATATTGAGCAAACGGGCAATGCCAACGATGCCAGTATATCGCAA
+AGCGCTTACGGTAATAGTGCGGCTATTATCCAGAAAGGTTCTGGAAATAAGGCCAATATT
+ACCCAGTACGGTACGCAGAAAACAGCAGTTGTAGTGCAGAAACAGTCGCATATGGCTATT
+CGCGTCACCCAACGCATGCATACTTTATTGCTCCTTGCCGCACTTTCAAATCAGATTACG
+TTTACCACGACTCAGCAAGGCGATATTTACACGGTGATCCCTCAGGTCACATTAAACGAA
+CCCTGCGTCTGTCTGGTGCAAATTCTCTCTGTGCGCGACGGCGTCGGGGGACAAAGCCAT
+ACACAGCAAAAACAAACGCTATCTTTACCTGCTAATCAACCGATTGAGTTGTCTCGTCTT
+AGTGTAAATATATCTTCAGAGGACTCGGTTAAAATTATTGTTACTGTTTCGGACGGACAA
+TCACTGCATTTATCACAACAATGGCCGCCTTCTGCACAGATGTTTAATGAAGTCCATAGT
+AGTCATGGTCACACACTATTGTTGATCACAAAGCCATCTCTGCAAGCTACGGCATTATTG
+CAACATTTAAAGCAATCGCTGGCCATAACCGGAAAACTGCATAATATTCAACGTTCTCTG
+GAAGATATCTCAGCCGGTTGCATTGTTTTAATGGATATGATGGAAGCGGATAAGAAGCTT
+ATCCACTATTGGCAGGATAATTTAAGCCGCAAAAACAATAATATAAAAACATTATTGTTA
+AATACCCCTGACGATTATCCCTACCGTGAAATTGAAAACTGGCCTCATATTAACGGCGTG
+TTTTACGCCACTGAAGACCAGGAACACGTGGTCAGCGGATTACAGGGTATTCTGCGGGGC
+GAATGCTATTTTTCACAAAAATTAGCCAGTTACCTGATTACACACTCAGGAAATTACCGC
+TACAACAGCACCGAGTCCGCATTACTCACTCATCGCGAAAAAGAGATCCTCAATAAGTTA
+CGTATTGGTGCCTCTAATAATGAAATCGCCAGGTCGCTATTTATCAGCGAGAATACGGTT
+AAGACACATCTTTATAATCTTTTCAAAAAGATAGCTGTCAAAAATCGCACCCAGGCAGTT
+TCAATGAAACGCTATCTGACCTGGATTGTAGCAGCAGAGTTACTGTTCGCTACCGGAAAC
+CTGCATGCCAATGAAGTTGAAGTCGAGGTTCCCGGATTGTTAACCGACCATACCGTCTCT
+TCGATAGGACATGAATTCTATCGTGCATTCAGCGACAAATGGGAAAGCGAATACACCGGC
+AATCTGACCATTAATGAAAGACCCAGTGCGCGTTGGGGAAGCTGGATCACCATAACGGTA
+AATCAGGACGTTATTTTCCAGACCTTTTTATTTCCAATGAAAAGAGACTTCGAGAAAACC
+GTCGTCTTCGCATTAGCGCAAACAGAGGAAGCATTAAATCGCCGACAAATAGATCAAACG
+CTATTAAGTACGAGTGATTTAGCGCGTGATGAATTCATGCGTGTTAAACATGCAGTAGTG
+CTGCTCATGCTTTTTTCGCCATTAACCTGGGCTGGAAATATGACGTTCCAGTTCCGTAAT
+CCTAACTTTGGTGGAAACCCCAATAACGGTTCCTTTTTATTGAATAGCGCCCAGGCGCAA
+AATTCATATAAAGACCCCGCTTATGATAACGATTTTGGTATCGAGACCCCCTCAGCGTTG
+GATAACTTTACGCAGGCTATTCAATCGCAAATTCTGGGCGGCTTGTTGACCAATATTAAT
+ACCGGAAAACCAGGACGTATGGTGACCAATGATTTTATTATCGATATCGCTAATCGCGAC
+GGACAGCTCCAGCTCAACGTCACGGACAGAAAAACGGGAAGAACCTCGACCATCGAAGTG
+TCAGGTTTACAAACTCAGTCAACCGATTTTATGCCGCGCTTACTTATTTTGGTTGCCGTT
+TTATTGTTGAGCGGATGCTTAACTGCCCCGCCGAAACAAGCTGCGAAACCGACATTAATG
+CCCCGCGCACAAAGTTACAAAGATTTGACGCACTTACCTGCTCCCACCGGTAAGATCTTT
+GTTTCGGTATATAACATTCAGGATGAAACGGGCCAATTTAAACCTTACCCGGCAAGTAAC
+TTTTCCACGGCTGTGCCGCAGAGCGCCACCGCTATGTTGGTCACCGCGCTGAAAGATTCG
+CGCTGGTTTATCCCACTAGAACGACAAGGCTTACAGAATCTTTTGAATGAACGGAAAATT
+ATTCGCGCAGCCCAGGAAAACGGCACCGTGGCGATGAATAACCGTATCCCGCTTCAGTCG
+TTGACGGCGGCAAATATTATGGTGGAAGGTTCTATTATTGGTTATGAAAGTAACGTCAAA
+TCCGGCGGGGTCGGCGCAAGATATTTCGGTATTGGCGCCGATACGCAGTATCAGCTGGAT
+CAGATTGCTGTCAACCTGCGCGTGGTTAACGTCAGTACGGGCGAGATCCTTTCTTCGGTG
+AACACCAGTAAAACGATCCTTTCCTATGAAGTACAGGCAGGCGTGTTCCGTTTTATTGAT
+TACCAGCGCTTACTGGAAGGCGAAATCGGCTATACCTCGAACGAACCGGTGATGCTGTGT
+CTGATGTCAGCCATTGAAACCGGCGTTATCTTCCTCATTAATGATGGTATCGATCGCGGA
+CTGTGGGATTTGCAGAATAAAGCGGACAGGCAAAATGATATTCTGGTGAAATACCGTGAG
+CTGTCAGTACCGCCAGAATCCATGTCTATTGCCGTAAATATGAATGACCCGACCAACACG
+GGCGTCAAAACGACGACCGGCAGCGGGTCGATGACCGGAAGCAACGCTGCCGATCTGCAA
+AGCAGTTTCCTGACCTTACTGGTCGCGCAATTGAAGAACCAGGACCCGACTAACCCATTA
+CAAAATAATGAGTTAACGACACAGTTGGCGCAAATCAGTACCGTGAGCGGCATTGAAAAA
+CTGAATACGACGCTGGGGGCTATTTCCGGGCAAATCGATAATAGTCAGTCCCTACAGGCG
+ACCACGCTGATTGGACATGGCGTTATGGTGCCTGGCACCACAATTCTGGCGGGTAAAGGC
+GCGGAAGAAGGGGCCGTGACGTCCACGACGCCGTTTGGCGTGGAATTGCAACAGCCTGCG
+GACAAAGTGACGGCAACCATTACCGATAAAGATGGCCGGGTGGTACGGACGCTGGAGATC
+GGTGAGTTGCGAGCCGGGGTACACACCTTTACCTGGGATGGTAAGCAAACGGACGGAACA
+ACGGTACCGAATGGTTCTTACAACATTGCGATTACCGCCAGCAATGGCGGGACGCAACTG
+GTGGCGCAGCCGCTGCAATTCGCTCTGGTACAGGGCGTGACGAAGGGCAGTAACGGCAAC
+CTGTTGGATCTGGGTACCTACGGCACCACCACACTCGACGAAGTTCGGCAAATAATCTAA
+ATGTCTTTTTCTCAAGCGGTTAGCGGCCTGAACGCTGCGGCCACCAACCTTGATGTTATC
+GGTAATAACATCGCCAACTCCGCCACCTATGGCTTTAAGTCCGGTACGGCATCATTTGCC
+GATATGTTCGCCGGTTCCAAAGTGGGGTTGGGCGTAAAAGTGGCGGGGATTACCCAGGAT
+TTTACCGACGGTACGACAACGAACACCGGGCGCGGGCTGGATGTCGCGATTAGCCAGAAC
+GGTTTTTTCCGCCTGGTAGACAGCAACGGTTCCGTGTTCTATAGCCGCAACGGCCAGTTC
+AAACTGGACGAGAACCGTAACCTGGTCAATATGCAGGGGATGCAGTTGACCGGCTATCCG
+GCCACCGGTACGCCGCCGACCATTCAGCAGGGGGCGAATCCTGCGCCGATCACCATTCCG
+AACACGCTGATGGCGGCGAAATCGACCACCACCGCGTCAATGCAGATCAACCTGAACTCA
+ACGGACCCTGTACCGTCTAAAACGCCCTTTAGCGTGAGTGATGCGGATTCGTATAACAAA
+AAAGGCACCGTCACCGTTTATGACAGCCAGGGTAATGCCCATGACATGAACGTCTATTTT
+GTGAAAACCAAAGATAATGAATGGGCTGTGTACACCCATGACAGCAGCGATCCTGCAGCC
+ACTGCGCCAACAACGGCGTCCACTACGCTGAAATTCAATGAAAACGGGATTCTGGAGTCT
+GGCGGTACGGTGAACATCACCACCGGTACGATTAATGGCGCGACAGCGGCCACCTTCTCC
+CTCAGCTTCCTTAACTCCATGCAGCAGAACACCGGGGCTAATAACATCGTCGCCACCAAT
+CAAAACGGCTATAAGCCTGGCGACCTGGTGAGCTACCAGATTAACAATGATGGCACCGTG
+GTTGGCAACTACTCCAACGAGCAGGAGCAGGTGCTGGGGCAGATTGTGCTGGCTAACTTC
+GCCAACAACGAAGGTCTGGCATCCCAGGGCGATAACGTCTGGGCGGCGACGCAGGCCTCC
+GGGGTAGCGCTGCTGGGGACTGCCGGTTCCGGCAACTTCGGTAAGCTGACGAACGGCGCG
+CTGGAAGCCTCTAACGTGGATTTGAGTAAAGAGCTGGTGAATATGATCGTCGCGCAGCGT
+AACTACCAGTCGAATGCGCAGACCATCAAAACCCAGGACCAGATCCTCAATACGCTGGTT
+AACCTGCGCTAAATGGATCACGCAATTTATACCGCCATGGGGGCGGCCAGCCAGACGCTT
+AACCAGCAGGCGGTAACGGCCAGCAACCTGGCTAATGCCTCAACGCCGGGCTTTCGCGCG
+CAGCTTAACGCGCTACGCGCGGTGCCCGTTGATGGCCTCTCTTTAGCGACGCGCACGTTG
+GTTACGGCGTCGACGCCGGGGGCGGATATGACCCAGGGTCAGTTGGACTACACTTCCCGC
+CCGCTGGATGTTGCGTTACAGCAGGACGGCTGGCTGGTGGTGCAAGCGGCGGATGGCGCT
+GAAGGATATACCCGTAACGGGAATATCCAGGTGGGCCCGACCGGGCAGTTAACCATTCAG
+GGACATCCGGTTATCGGCGAAGGCGGCCCGATTACCGTTCCGGAAGGGTCGGAAATCACC
+ATTGCGGCAGACGGCACGATCTCCGCGCTCAATCCCGGCGACCCGCCAAACACGGTGGCG
+CCCGTTGGGCGGCTGAAGCTGGTCAAAGCGGAAGGCAATGAGGTGCAGCGGAGCGATGAC
+GGTTTATTCCGCCTTACCGCCGAGGCACAGGCTGAACGCGGGGCGGTACTGGCCGCCGAC
+CCGTCAATTCGCATTATGTCGGGCGTGCTGGAGGGCAGTAACGTCAAGCCGGTTGAAGCC
+ATGACCGACATGATCGCCAACGCACGTCGTTTTGAAATGCAGATGAAGGTTATCACCAGC
+GTAGATGAGAACGAAGGGCGAGCTAACCAACTGCTGTCGATGAGTTAAATGATCAGTTCA
+TTATGGATCGCCAAAACCGGTCTGGACGCGCAGCAAACCAATATGGATGTGATTGCCAAT
+AACCTGGCAAACGTCAGCACCAATGGTTTTAAGCGTCAGCGCGCGGTATTTGAAGATCTG
+TTGTATCAGACCATCCGCCAGCCGGGCGCGCAGTCGTCCGAGCAGACGACGCTGCCTTCC
+GGGCTGCAAATCGGTACCGGCGTGCGTCCGGTCGCCACGGAGCGCCTGCACAGTCAGGGG
+AACCTGTCGCAGACCAACAACAGTAAAGATGTGGCGATTAAAGGGCAGGGCTTTTTCCAG
+GTCATGCTGCCGGACGGTACGTCTGCCTATACCCGCGACGGCTCTTTCCAGGTGGATCAG
+AATGGTCAACTGGTGACGGCGGGCGGTTTTCAGGTGCAGCCGGCAATCACCATTCCGGCC
+AACGCGTTAAGCATCACGATTGGCCGCGACGGCGTGGTCAGCGTTACCCAGCAAGGGCAG
+GCCGCGCCGGTTCAGGTCGGGCAGCTTAACCTGACCACCTTTATGAACGACACCGGTCTG
+GAAAGCATCGGCGAGAACCTCTATATCGAAACGCAATCGTCCGGCGCGCCGAACGAAAGC
+ACGCCGGGGCTCAACGGCGCGGGGTTGTTGTATCAAGGGTATGTCGAAACGTCGAACGTT
+AACGTGGCGGAAGAGCTGGTGAACATGATTCAGGTTCAACGCGCCTATGAAATTAACAGT
+AAAGCAGTATCGACGACCGATCAGATGCTGCAGAAACTGACGCAACTCTAAATGGCCCTG
+ATGGTCGCGACGCTGACAGGATGCGCCTGGATACCCGCTAAACCGCTCGTGCAGGGGGCG
+ACCACGGCGCAGCCGATACCTGGCCCGGTACCGGTGGCGAATGGCTCCATATTTCAGTCT
+GCGCAGCCGATTAATTATGGCTATCAGCCGCTTTTTGAAGATCGTCGACCGCGTAATATC
+GGCGATACGCTCACGATTGTGTTACAGGAAAACGTCAGCGCCAGTAAAAGCTCGTCGGCA
+AATGCCAGCCGCGACGGCAAAACCAGCTTTGGTTTTGATACGGTACCGCGTTATCTGCAG
+GGATTATTCGGTAATTCCCGCGCGGATATGGAGGCCTCCGGCGGCAACTCTTTTAATGGT
+AAAGGCGGCGCGAATGCCAGCAATACCTTTAGCGGCACGCTGACCGTGACCGTCGATCAG
+GTTCTGGCCAATGGCAATTTACACGTCGTGGGGGAAAAACAGATCGCGATTAATCAGGGA
+ACGGAATTCATCCGCTTCTCCGGCGTGGTAAATCCACGCACCATCAGCGGTAGCAACTCT
+GTTCCCTCGACACAGGTGGCGGATGCGCGGATTGAATATGTCGGGAACGGCTATATTAAC
+GAAGCGCAAAATATGGGCTGGCTGCAACGTTTCTTCCTTAATTTGTCGCCGATGTAAGTG
+TTTAAAGCTCTTGCAGGAATCGTTCTGGCACTGGTTGCCACTCTGGCGCACGCCGAGCGT
+ATCCGGGATCTGACCAGTGTCCAGGGAGTACGGGAAAACTCGCTGATCGGCTACGGGCTG
+GTGGTCGGGCTGGACGGTACGGGCGACCAGACGACCCAGACGCCATTTACCACCCAGACG
+CTGAATAACATGCTGTCACAACTGGGGATTACGGTCCCCACCGGCACCAATATGCAGTTG
+AAAAACGTGGCGGCGGTGATGGTGACGGCGTCGTATCCGCCTTTTGCGCGACAGGGACAA
+ACGATCGATGTCGTCGTTTCCTCAATGGGGAACGCTAAAAGTCTGCGTGGCGGGACGTTA
+TTAATGACGCCGTTAAAAGGGGTGGACAGCCAGGTGTATGCTCTGGCGCAGGGCAATATT
+CTGGTCGGCGGCGCGGGCGCTTCCGCAGGCGGCAGTAGCGTGCAGGTTAACCAGCTTAAT
+GGCGGGCGCATCACTAATGGCGCGATTATCGAACGCGAGTTGCCGACTCAGTTCGGCGCT
+GGCAACACCATTAATCTGCAATTGAACGACGAAGATTTTACGATGGCGCAGCAAATTACC
+GACGCCATCAACCGCGCCCGCGGTTACGGCAGCGCCACTGCGCTTGATGCGCGAACGGTA
+CAGGTACGCGTGCCCAGCGGCAACAGCTCGCAGGTGCGTTTTCTGGCGGACATTCAAAAT
+ATGGAAGTCAACGTGACGCCGCAGGATGCAAAAGTCGTGATCAACTCGCGTACCGGTTCG
+GTGGTCATGAATCGGGAAGTCACGCTGGATAGCTGCGCTGTGGCGCAGGGCAATTTGTCA
+GTGACAGTCAATCGCCAACTCAACGTCAACCAGCCGAATACGCCATTTGGCGGCGGGCAG
+ACCGTGGTGACGCCACAGACTCAGATAGATTTGCGTCAGAGCGGCGGATCGCTACAGAGC
+GTGCGTTCCAGCGCCAATCTGAACAGCGTAGTGCGCGCGCTGAATGCGCTTGGCGCGACG
+CCGATGGATCTGATGTCGATTTTGCAGTCCATGCAGAGCGCGGGCTGTCTACGCGCCAAA
+CTGGAAATCATCTGAATGATCGGAGACGGTAAATTGCTGGCCAGCGCGGCCTGGGATGCG
+CAATCTCTGAACGAACTGAAAGCGAAAGCGGGCCAGGACCCGGCGGCGAATATCCGTCCT
+GTGGCCCGTCAGGTGGAAGGGATGTTTGTGCAGATGATGCTGAAAAGTATGCGCGAGGCT
+TTACCCAAAGATGGTTTATTCAGCAGCGATCAGACGCGTCTGTATACCAGCATGTATGAC
+CAGCAGATCGCCCAGCAGATGACCGCCGGTAAGGGATTGGGGCTGGCGGATATGATGGTT
+AAACAGATGACGGGCGGGCAGACGATGCCTGCAGATGATGCGCCGCAAGTACCGCTTAAA
+TTCTCCCTGGAGACGGTAAACAGCTATCAAAATCAGGCGCTGACCCAACTGGTGCGCAAA
+GCCATACCGAAAACGCCGGACAGCAGCGATGCGCCGCTCTCCGGCGACAGTAAAGACTTT
+CTGGCCCGGCTTTCGCTCCCGGCGAGGCTGGCCAGCGAACAAAGCGGGGTGCCGCATCAT
+CTGATTCTGGCGCAGGCGGCGCTGGAGTCCGGCTGGGGGCAGCGGCAAATCCTGCGGGAG
+AATGGCGAACCCAGCTATAACGTATTTGGCGTGAAAGCGACCGCCAGTTGGAAAGGGCCG
+GTGACGGAAATCACCACCACTGAATACGAAAATGGCGAAGCGAAAAAAGTGAAAGCGAAA
+TTCCGCGTCTATAGCTCGTATCTGGAGGCGTTATCGGATTATGTCGCGCTGTTAACGCGT
+AACCCACGCTACGCTGCCGTGACCACTGCCGCCACGGCAGAGCAGGGCGCAGTGGCTCTG
+CAAAACGCCGGATACGCCACTGACCCGAATTACGCGCGTAAATTGGCCAGCATGATTCAG
+CAGTTGAAAGCGATGAGTGAAAAGGTCAGCAAAACCTACAGCGCGAATCTCGACAATCTC
+TTTTAAATGTCCAGCTTGATTAATCACGCCATGAGCGGACTTAACGCCGCGCAGGCCGCG
+TTAAATACGGTCAGTAATAACATCAACAATTATAACGTTGCGGGTTATACCCGGCAGACA
+ACTATTCTGGCGCAGGCAAACAGTACGTTAGGGGCTGGCGGCTGGATAGGTAATGGCGTT
+TACGTTTCAGGCGTACAGCGCGAATATGATGCGTTTATCACTAATCAGCTACGCGGCGCG
+CAAAACCAGAGCAGCGGCTTAACCACGCGCTATGAACAAATGTCGAAAATCGACAACCTG
+CTGGCCGATAAATCCAGCTCACTGTCTGGCTCGCTGCAGAGTTTTTTTACCAGCCTGCAA
+ACGTTAGTCAGTAATGCGGAAGATCCTGCGGCGCGTCAGGCGCTGATTGGTAAAGCGGAA
+GGGCTGGTAAACCAGTTCAAAACCACCGATCAGTATCTGCGCGATCAGGATAAACAGGTC
+AATATCGCGATTGGCTCCAGCGTGGCGCAAATCAACAATTACGCGAAGCAGATAGCTAAC
+CTGAACGATCAAATCTCCCGTATGACGGGCGTAGGCGCGGGCGCATCGCCGAACGACCTG
+CTCGATCAACGTGATCAGTTGGTTAGCGAGCTTAACAAGATCGTTGGCGTCGAGGTGAGT
+GTACAGGACGGCGGCACCTATAACCTGACGATGGCCAATGGCTATACGCTGGTGCAGGGG
+TCGACGGCGCGTCAGTTGGCGGCGGTTCCCTCCAGCGCCGACCCGACGCGAACGACTGTC
+GCTTATGTCGATGAGGCCGCCGGTAACATCGAAATTCCGGAAAAGTTGCTGAACACCGGT
+TCGCTCGGCGGGCTACTGACGTTCCGTTCTCAGGATCTGGATCAGACTCGTAATACGCTG
+GGCCAGTTGGCGTTGGCGTTTGCCGATGCGTTTAACGCGCAGCATACCAAAGGTTATGAC
+GCCGACGGCAATAAAGGGAAAGACTTCTTTAGCATTGGCTCGCCGGTGGTATATAGCAAC
+AGTAATAATGCCGATAAAACGGTATCGCTAACCGCTAAGGTGGTCGACAGCACGAAGGTT
+CAGGCGACGGATTATAAGATTGTTTTTGACGGTACAGACTGGCAGGTTACTCGCACTGCG
+GATAACACCACCTTCACGGCAACAAAAGATGCTGACGGAAAACTGGAGATTGACGGTCTG
+AAAGTGACGGTAGGGACTGGCGCACAGAAAAACGACAGTTTTCTTCTCAAGCCGGTCAGC
+AATGCTATCGTCGACATGAACGTTAAAGTGACAAATGAAGCCGAGATTGCGATGGCGTCT
+GAGTCAAAACTCGATCCTGATGTGGATACCGGCGACAGCGATAACCGCAATGGTCAGGCA
+TTGCTGGACTTACAAAACAGCAATGTAGTGGGCGGCAACAAAACCTTTAACGATGCTTAC
+GCCACGTTGGTCAGCGATGTGGGTAACAAAACGTCAACGCTGAAAACCAGCAGCACCACG
+CAGGCGAATGTGGTTAAACAGCTTTATAAACAGCAACAGTCGGTTTCCGGCGTTAACCTC
+GACGAAGAGTACGGCAATTTGCAGCGTTATCAGCAGTATTATCTGGCGAATGCGCAAGTA
+TTGCAGACCGCGAATGCGCTGTTTGATGCGTTATTGAATATTCGCTAAATGCGTATCAGT
+ACCCAGATGATGTACGAACAAAATATGAGCGGCATCACTAATTCTCAGGCCGAATGGATG
+AAGCTGGGCGAGCAGATGTCTACCGGTAAGCGCGTTACCAACCCATCTGACGATCCGATC
+GCCGCGTCGCAGGCGGTAGTACTCTTTCAGGCGCAGGCGCAGAATAGCCAGTACGCCCTG
+GCGCGTACGTTTGCCACCCAAAAAGTGTCGCTGGAAGAAAGCGTACTCAGTCAGGTGACG
+ACGGCGATTCAAACCGCGCAGGAAAAAATCGTCTATGCCGGAAACGGCACGTTAAGCGAC
+GATGACCGCGCGTCGCTGGCGACGGATTTACAGGGGATCCGCGATCAGCTGATGAACCTG
+GCAAACAGCACTGACGGCAATGGTCGCTATATCTTTGCCGGGTATAAAACGGAAGCGGCG
+CCATTCGACCAGGCGACAGGTGGTTATCATGGCGGCGAGAAAAGTGTTACCCAGCAGGTG
+GATTCCGCACGCACGATGGTAATTGGCCATACGGGAGCGCAAATTTTTAATAGCATCACC
+AGCAATGCGGTGCCGGAACCGGATGGCTCGGACTCCGAAAAGAATCTGTTTGTCATGCTC
+GATACGGCAATTGCCGCGCTCAAGACCCCGGTGGAAGGCAATGACGTGGAAAAAGAAAAA
+GCCGCTGCCGCCATTGATAAAACCAATCGCGGCTTAAAAAATTCGCTTAATAACGTCCTG
+ACCGTTCGTGCGGAACTGGGAACGCAACTGAGCGAACTCAGTACGCTGGATTCACTGGGA
+AGCGACCGTGCGCTGGGACAGAAGCTACAGATGAGCAACCTGGTAGATGTGGACTGGAAC
+TCGGTCATTTCCTCCTACGTCATGCAACAGGCGGCATTACAGGCGTCCTATAAAACGTTT
+ACCGACATGCAGGGAATGTCGCTTTTCCAGTTGAACCGGTAAATGGAGATAATTTTTTAT
+CACCCGACATTTAACGCCGCCTGGTGGGTAAATGCGCTGGAGAAGGCTCTCCCACATGCG
+CGCGTTCGTGAATGGAAGGTCGGTGATAACAACCCCGCAGACTATGCGCTTGTATGGCAG
+CCCCCGGTTGAAATGCTGGCCGGAAGACGCTTAAAAGCCGTCTTTGTGCTGGGCGCGGGG
+GTGGATGCAATTCTGAGTAAATTAAATGCGCATCCGGAAATGCTGGACGCCTCCATTCCT
+CTATTCCGTCTGGAAGATACCGGAATGGGCCTGCAAATGCAGGAGTATGCCGCCAGCCAG
+GTATTACACTGGTTCCGTCGTTTCGATGATTATCAGGCGCTGAAAAATCAGGCGCTATGG
+AAACCGTTGCCGGAATATACCCGCGAAGAGTTTAGCGTCGGTATCATAGGCGCAGGGGTA
+CTGGGCGCAAAAGTGGCAGAAAGTCTACAGGCGTGGGGGTTCCCGTTACGTTGCTGGAGT
+CGTAGCCGCAAATCCTGGCCTGGCGTGGAAAGTTATGTAGGGCGTGAAGAACTGCGCGCT
+TTCCTGAACCAGACGCGGGTGCTGATTAATCTGCTGCCGAATACGGCCCAAACGGTAGGA
+ATTATTAATAGCGAATTGTTGGATCAATTGCCGGATGGCGCTTACGTGCTGAATCTCGCG
+CGCGGCGTTCATGTTCAGGAGGCGGATCTGCTGGCTGCGCTTGATAGCGGTAAGCTAAAA
+GGCGCGATGTTGGATGTCTTTAGCCAGGAACCGTTACCGCAGGAAAGTCCATTATGGCGC
+CATCCGCGAGTCGCCATGACGCCGCACATTGCGGCAGTCACCCGTCCGGCGGAAGCCATC
+GATTATATTAGCCGCACCATTACCCAGCTGGAGAAGGGAGAGCCGGTGACGGGGCAGGTG
+GATCGGGCGAGAGGATAT---ATGTCCGTAATCAAGAAAAATATCCCTGCCATAGGCCTG
+TGTATCTGCGCTTTTTTTATCCATTCTGCGGTAGGGCAACAAACGGTACAGGGCGGCGTT
+ATCCATTTTCGCGGCGCGATTGTTGAGCCACTGTGCGATATTTCTACTCACGCCGAAAAT
+ATTGATTTAACCTGCCTACGCGAAGGTAAAAAGCAAATGCACCGGATAGACCTTCGGCAG
+GCATCTGGATTACCGCAGGATATTCAGTCCATTGCGACGGTACGGCTGCATTATCTCGAT
+GCGCAAAAAAGCCTGGCGGTGATGAATATTGAGTACCGTTAAATGGCAAACCATCGTGGC
+GGTTCCGGTAATTTTGCGGAAGACCGCGAAAGAGCATCAGAAGCAGGTCGTAAAAGTGGT
+CAGCACAGCGGGGGCAATTTTAAGAATGACCCGCAGCGTGCATCCGAAGCAGGCAAAAAA
+GGGGGCAAAAGCAGTAACCGTAATCGCTAGATGGTAATGTCCGCACCAGGACACATTGTT
+TACAGTAGTTACAACACCCTGTACGGACATTCTCTCTCCGGTGGTGGTCTTGTCATCTTA
+AAAGCTCTCATCATTTCCCTTACTGTCCATACCCATGACGCCATATGTGGTGCGCGTAGC
+CGTGTGTGGCGTCGTTTCAAAAAGCAAGCTAAGGCTTACAAGGAAGCCAACCCTCAGATG
+TGTGTGCGCATAATCGCGTTCAAGAGAACGCGGGTGATGTATACCTACAACTCAAGGTGC
+TATCCATGGGAAGACAAAAAGCAGTGAATGAAACGAATTTTCCTTACCTGCGCGGCGTTG
+TTGTTCAGCAGTCAGGCGTTGGCCGATGAGTGTGCCAGCGCCAGTACGCAGCTGGAAATG
+AATCGCTGCGCCGCCGCGCAATACCAGGCGGCAGATAAAAAGCTGAACGAAACCTATCAA
+AGCGCGATTAAGCGTGCGCAACCGCCGCAGCGTGAGCTATTGCAAAAAGCGCAGGTGGCA
+TGGATTGCCCTGCGCGACGCCGATTGCGCGCTGATTCGCTCAGGTACGGAGGGCGGCAGC
+GTTCAACCCATGATCGCCAGCCAGTGCCTGACCGATAAAACGAACGAACGCGAAGCGTTT
+TTAGCCTCGCTGCTGCAATGTGAAGAGGGTGATTTGAGCTGCCCACTGCCGCCAGCCGGT
+TAAGTGCGTATATTCGCGGTGAGCATAATGGTGATTACCCTGAGCGGCTGCGGCAGTATT
+ATCAGCAGAACGATCCCCGGACAAGGACACGGCAACCAGTATTACCCTGGCGTGCAGTGG
+GATATGCGTGATTCCGCATGGCGCTATATCACTATCCTCGATCTGCCCTTCTCACTGATC
+TTCGATACACTGCTACTGCCGCTCGATATTCACCACGGGCCTTATGAGATGTGCCAACGT
+GCGATCGCCAATATTGATATCAGCAAAGAGTATGACGAAAGCATGGGCAGTAACGATGTG
+CATTATCAGTCGTTTGCTCGTATGGCGGATTTCTTTGGTCGTGATATGCAGGCGCATCGC
+CACGACCAGTTTTTTCAAATGCACTTTCTTGATACCGGGCAGATTGAGCTACAGCTCGAC
+GATCATCGCTATTCGGTGCAGGCGCCGCTATTTGTGCTAACGCCGCCCTCGGTGCCGCAT
+GCTTTTATTACCGAATCGGATAGCGATGGTCATGTTCTGACGGTACGCGAAGAGCTGGTT
+TGGCCGCTGCTGGAAGTGCTTTATCCCGGCACCAGAGAGGCCTTCGGCCTGCCGGGAATC
+TGCCTGTCGCTGGCGGATAAACTCAACGAGCTGGCGGCGCTCAAACATTACTGGCAGCTA
+ATTGAGCGGGAGTCCACGGAACAACTGGCTGGCTGCGAACATACCTTGGTACTACTGGCG
+CAGGCGGTATTTACCTTGCTGTTGCGTAATGCGAAGCTGGACGATCATGCCGCAACCGGG
+ATGCGCGGTGAACTGAAACTTTTTCAGCGCTTTACCCTGTTAATTGACAACCACTTCCAT
+CAGCACTGGACGGTGCCCGATTATGCCTGTGAGTTGCATATTACCGAATCTCGTTTGACC
+GATATTTGCCGACGTTTTGCTAATCGCCCGCCTAAACGCCTGATTTTTGATCGGCAATTA
+CGCGAGGCGAAACGACTGCTGCTTTTTTCCGACAATGCTGTCAACGAGATCGCCTGGCAA
+TTAGGTTTTAAAGATCCGGCTTATTTCGCCCGTTTCTTTAATCGCCTTGCTGGCTGTTCT
+CCTTCGCAGTTTCGCCAACGTGAAGTTCCTTCTTTTCTCAACTAAATGGGACGCACACCG
+GATTACAAAGCCGCCTTTGGCTGCGCTCTGGGCGCTAACCCAGCCTTCTACGGCCAGTTT
+GAGCAGAACGCCCGTAACTGGTACACCCGTATTCAGGAGACCGGCCTGTACTTTAACCAT
+GCAATCGTCAACCCGCCCATTGACCGCCACAAACCTGCCGACGAAGTGAAAGACGTCTAT
+ATCAAGCTGGAGAAAGAGACGGACGCCGGGATTATTGTCAGCGGGGCGAAAGTTGTCGCC
+ACTAACTCCGCCCTGACTCACTACAACATGATTGGTTTCGGCTCAGCCCAGGTGATGGGC
+GAAAACCCGGATTTTGCTCTGATGTTTGTCGCGCCAATGGATGCCGAAGGCGTAAAACTT
+ATTTCGCGCGCCTCGTATGAAATGGTCGCGGGCGCGACGGGCTCGCCGTTTGATTATCCC
+CTCTCCAGCCGTTTTGATGAAAACGATGCCATTCTGGTGATGGACAAGGTGCTGATCCCG
+TGGGAAAACGTATTAATTTACCGTGATTTCGATCGTTGTCGTCGCTGGACGATGGAAGGC
+GGCTTTGCCCGTATGTATCCACTGCAAGCCTGTGTTCGTCTGGCGGTAAAACTTGATTTC
+ATTACCGCGCTGCTGAAAAAATCGCTCGAATGTACGGGTACCGTAGAGTTCCGGGGCGTG
+CAGGCCGATCTCGGCGAAGTCGTGGCCTGGCGCAATATGTTCTGGGCATTGAGCGATTCT
+ATGTGTTCTGAAGCAACCCCGTGGGTAAACGGCGCCTGGCTACCGGACCACGCCGCGCTG
+CAAACCTATCGTGTGATGGCCCCAATGGCCTACGCGAAAATTAAAAATATTATTGAACGT
+AACGTTACCAGCGGCCTGATTTACCTGCCTTCCAGCGCCCGCGATCTGAATAATCCGCAA
+ATCGACCAGTACCTGGCGAAATACGTACGCGGCTCTAACGGAATGGACCATGTTGAACGT
+ATCAAAATTCTTAAATTGATGTGGGATGCCATCGGCAGCGAGTTTGGCGGTCGCCATGAG
+CTGTACGAGATTAACTACTCGGGCAGCCAGGATGAAATTCGTCTGCAGTGTCTGCGTCAG
+GCCCAGAGCTCCGGCAATATGGATAAGATGATGGCAATGGTCGATCGCTGCCTCTCCGAA
+TACGATCAGAATGGCTGGACGGTTTCGCATTTGCACAATAACGACGACATCAATCAACTG
+GATAAGCTGCTGAAATAAATGCAAGTAGATGAACAACGTCTGCGTTTTCGCGATGCGATG
+GCAAGTCTGGCGGCAGCGGTCAACATCGTAACCACGGCGGGTCACGCCGGACGCTGCGGT
+ATCACCGCAACAGCGGTTTGCTCAGTCACTGATACGCCGCCCTCCGTGATGGTATGTATT
+AATGCCAATAGCGCCATGAACCCCGTTTTTCAGGGCAACGGCAGGCTGTGCATTAATGTA
+CTTAACCATGAGCAGGAGCTGATGGCGCGCCACTTTGCCGGTATGACGGGGATGGCGATG
+GAGGAGCGTTTTCACCAGCCATGTTGGCAAAACGGGCCGCTGGGCCAGCCGGTACTTAAC
+GGCGCGCTGGCCAGTCTTGAAGGCGAGATCAGCGAGGTACAAACCATTGGCACGCATCTG
+GTGTATCTGGTGGCGATCAAAAATATTATTCTTAGCCAGGAGGGGCATGGCCTGATTTAT
+TTCAAACGCCGTTTTCATCCGGTCAGACTTGAGATGGAAGCGCCTGTTTAAATGAAGGGT
+ACTGTTTTCGCCGTTGCGTTAAACCATCGCAGCCAGCTTGATGCCTGGCAAGAGGCTTTC
+TCTCAGCCTCCCTATAATGCGCCGCCTAAAACCGCAGTGTGGTTCATCAAGCCGCGTAAT
+ACGGTGATTCGTCACGGCGAACCCATTCCTTATCCGCAGGGAGAAAAGGTACTGAGCGGC
+GCGACAGTGGCGCTCATTGTGGGGAAAACCGCCAGCCGGATACGCCCTGAAGCGGCGGCG
+GACTATATCGCCGGGTATGCGCTGGCTAACGAGGTCAGCCTGCCGGAAGAGAGCTTTTAT
+CGCCCGGCGATTAAAGCGAAATGTCGCGATGGCTTTTGCCCGCTGGGTGAAATGGCGCCG
+CTGAGTGATGTGGATAATCTCACCATTATCACTGAAATCAACGGACGAGAAGCGGACCAC
+TGGAATACTGCCGATTTACAGCGTAGCGCCGCACAACTGCTTAGCGCGTTAAGTGAGTTC
+GCTACACTTAACCCTGGCGATGCGATCTTACTTGGTACGCCGCAGAATCGCGTTGCGCTG
+CGTCCCGGCGATCGGGTGCGTATTCTGGCGAAAGGTTTACCCGCGCTGGAAAATCCGGTT
+GTCGCAGAAGATGAATTCGCCCGCCACCAGACGTTTACGTGGCCGCTGTCAGCGACGGGA
+ACGTTATTTGCGCTGGGGTTGAACTACGCCGATCACGCCAGCGAGCTGGCATTTACGCCG
+CCGAAAGAGCCGCTGGTATTTATCAAAGCGCCAAACACCTTTACCGAACATCACCAAACG
+TCGGTGCGCCCGAACAACGTCGAATATATGCACTACGAAGCCGAGCTGGTCGTGGTGATT
+GGCAAAACGGCGCGTAAGGTGAGCGAAGCCGAAGCCATGGAGTATGTGGCCGGTTACACC
+GTCTGTAACGACTACGCGATCCGCGACTATCTGGAAAACTACTACCGTCCGAATCTGCGG
+GTAAAAAGCCGCGACGGCCTGACGCCGATAGGCCCGTGGATTGTGGATAAAGAGGCGGTT
+TCTGATCCGCACAACCTGACGTTACGCACCTTTGTCAACGGTGAGCTGCGGCAGGAAGGG
+ACGACCGCCGATCTGATCTTCAGCATCCCGTTCCTGATTTCTTATCTGAGCGAATTTATG
+ACGTTGCAACCGGGCGACATGATTGCCACCGGTACGCCGAAAGGGCTGTCCGATGTGGTG
+CCGGGGGATGAAGTTGTCGTTGAAGTAGAAGGCGTGGGTCGCCTGGTTAACCGAATCGTC
+AGTGAGGAGAGCGCAAAATGAATGAAAAATGCTTTCAAAGACGCGTTAAAAGCGGGGCGC
+CCGCAAATCGGTTTGTGGCTGGGGCTTGCCAACAGTTACAGCGCTGAACTGTTAGCGGGC
+GCCGGCTTCGACTGGCTACTGATTGACGGTGAACACGCGCCAAACAACGTGCAGACGGTG
+TTGACCCAGTTGCAGGCGATTGCGCCTTATCCCAGCCAGCCGGTGGTGCGTCCGTCATGG
+AACGATCCGGTACAGATTAAGCAACTGCTCGACGTCGGCGCGCAAACGCTGCTGATACCG
+ATGGTGCAGAATGCCGATGAAGCGCGAAACGCCGTGGCGGCTACGCGTTATCCGCCTGCC
+GGTATTCGCGGCGTGGGCAGCGCGCTGGCGCGGGCATCGCGCTGGAATCGCATTCCGGAC
+TATCTCCACCAGGCCAACGACGCCATGTGCGTACTGGTGCAGATTGAAACGCGTGAGGCG
+ATGAGCAATCTGGCGTCAATTCTCGACGTGGATGGCATTGACGGCGTGTTTATTGGCCCG
+GCGGATCTCAGCGCCGATATGGGCTTTGCCGGCAATCCGCAGCACCCGGAAGTGCAGGCG
+GCGATTGAGAACGCCATCGTGCAGATACGCGCGGCGGGGAAAGCGCCGGGGATTCTGATG
+GCCAATGAAGCACTGGCGAAACGTTATCTGGAACTGGGGGCGCTATTTGTCGCCGTCGGC
+GTTGACACCACGCTGCTGGCGCGCGGAGCGGAGGCGCTGGCGGCGCGCTTTGGCGCAGAA
+AAAAAACTGTCCGGTGCGTCCGGCGTCTATTAAATGCATGATTCATTAACCATCGCCTTG
+CTTCAGGCGCGCGAAGCGGCAATGACCTATTTCCGCCCCATCGTTAAAAGCCACAATCTG
+ACCGACCAGCAATGGCGCATTGTGCGAATCCTGGCCGATAGCCCCTCTATGGATTTTCAC
+GAGCTGGCCTTTCGTACCTGTATTTTGCGTCCAAGTCTGACCGGAATATTGACGCGCATG
+GAGCGAGACGGACTGGTGTTGCGACTCAAGCCGGTTAACGATCAGCGTAAGTTATATGTC
+ATGTTGACGGAGCAGGGACAAACGTTGTACGCCCGTGCCCGGAGCGAGGTAGAAGAGGCT
+TATCGAAAAATTGAGGCCGATTTCACGCCCGAAAAAACACAGCAATTGATGCTGCTGCTG
+GACGATCTTATTGCTCTGGGGCGCCAGCATCCTGATAGCGAAGCGGAAGCATAGATGAGC
+GACACATCATCTGCACTTCCGGAAAGCCCCGAGTCTGTCGGTTCGCACAACGCGCTCAGC
+ACGGGTCAACAAACCGTCATAAATAAACTGTTCCGCCGACTGATCGTATTTTTATTCGTG
+TTGTTTATCTTCTCGTTTTTAGACCGTATCAACATCGGTTTTGCCGGGTTGACGATGGGG
+CAGGATCTGGGGTTAAGCGCCACCATGTTTGGTCTTGCCACGACGCTGTTTTACGCCACC
+TACGTCATTTTCGGCATTCCCAGCAACGTGATGTTGAGCATCGTCGGCGCCCGCCGCTGG
+ATTGCGACCATTATGGTGCTATGGGGCATTGCATCTACCGCCACGATGTTCGCGGTGGGA
+CCGAAAAGCCTGTATGTGCTGCGAATGCTGGTGGGCATTACCGAAGCGGGCTTTTTGCCA
+GGAATATTGCTCTATTTAACCTACTGGTTCCCGGCATTTTTCCGCGCCCGCGCCAACGCA
+TTATTTATGATTGCCATGCCGGCCACTACCGCGTTGGGGTCAATTGTCTCCGGCTATATT
+TTATCGCTGGACGGCATATTCAATCTGCATGGATGGCAGTGGTTATTCCTGTTGGAAGGA
+TTTCCGTCAGTTTTGTTAGGCATTATGGTCTGGTTTTACCTGGATGATACCCCGGCAAAA
+GCCAAATGGCTGACGGCAGAGGATAAAAAATGTTTGCAGGAGATGATGGATAATGATCGC
+CTGACGCTGGTTCAGCCTGAGGGGGCCATCAGCCATAACGCCATGCAGCAGCGTAGCCTG
+TGGCGCGAAGTATTCACGCCAATTGTACTGATGTATACGCTGGCCTATTTTTGCCTTACC
+AATACGCTTAGCGCCATTAGTATCTGGACGCCGCAAATCCTGAAAAGTTTTAATGAAGGC
+AGCAGCAATATCACCATCGGCCTGCTGGCGGCGATCCCGCAGATTTGTACTGTTCTGGGC
+ATGATTTACTGGAGCCGCCATTCGGACAAACATCAGGAGCGTAAACACCACACTGCGTTA
+CCGTTCCTGTTTGCCGCCGCGGGCTGGCTGCTGGCGTCGGCGACCGACCGTAACCTGATC
+CAGCTCCTGGGGATCGTGATGGCATCCACGGGTTCCTTTAGCGCGATGGCGATCTTCTGG
+ACCACGCCGGATCAGTCGATCAGTTTACGCGCCAGGGCGATAGGCATTGCGGTCATCAAT
+GCCACCGGCAATATTGGCTCCGCGCTCAGCCCGGTTATGATTGGCTGGCTAAAAGATATC
+ACTGGTAGCTTCAATAGCGGACTCTGGTTTGTCGCTTCTCTGTTAGTCGTCGGCGCCGCC
+ATTATCTGGCTCATTCCCATGAAAGCATCGCGTCCGCGCGCCACCCCTTGAATGGGCAAG
+TTAGCGTTAGCAGCAAAAATTACCCACGTGCCGTCGATGTATCTTTCTGAACTGCCAGGA
+AAAAATCACGGTTGTCGTCAGGCAGCCATTGATGGGCATATTGAAATTGGCAAGCGTTGC
+CGCGAAATGGGCGTTGACACCATTATCGTATTCGACACCCACTGGCTGGTGAATAGCGCT
+TACCACATTAATTGTGCCGACCATTTCCAGGGCGTCTATACCAGCAACGAATTGCCGCAC
+TTTATTCGCGACATGACCTATGACTATGACGGTAATCCGGCGCTCGGCCATCTGATCGCC
+GACGAGGCGGTCAAACTGGGCGTGCGCGCCAAAGCGCACAACATCCCGAGCCTGAAGCTG
+GAGTATGGCACGCTGGTGCCGATGCGCTACATGAACAGCGACAAGCACTTCAAAGTGGTC
+TCCATCTCGGCGTTCTGCACTGTGCATGATTTTGCCGACAGCCGCAAACTGGGCGAAGCC
+ATTCTCAAGGCGATTGAGAAATATGACGGTACCGTAGCGGTATTCGCCAGTGGTTCTCTG
+TCGCACCGTTTTATTGACGACCAACGGGCGGAAGAGGGGATGAACAGCTACACCCGCGAG
+TTCGATCATCAAATGGACGAGCGCGTGGTCAAGCTGTGGCGCGAAGGCAAATTCAAGGAG
+TTTTGCACCATGTTGCCGGAGTACGCCGACTACTGCTACGGCGAAGGCAACATGCACGAC
+ACGGTCATGCTACTGGGAATGCTGGGGTGGGACAAATACGACGGCAAGGTGGAGTTCATC
+ACCGACCTGTTCGCCAGCTCCGGTACCGGCCAGGTAAACGCTGTTTTCCCGCTGCCTGCG
+TAAATGAAGAAAATAAATCATTGGATTAACGGCAAAAACGTTGCAGGTAACGACTACTTC
+CAGACCACTAACCCGGCGACCGGTGATGTGCTGGCGGAAGTAGCCTCCGGCGGTGAAGCA
+GAAGTGAACCAGGCTGTCGCGGCGGCAAAAGAGGCGTTCCCGAAATGGGCCAACCTGCCG
+ATGAAAGAGCGCGCGCGCCTGATGCGCCGCCTTGGCGACCTGATTGACCAGCATGTGCCG
+GAAATCGCGGCGATGGAAACCGCCGACACCGGCCTGCCTATTCACCAGACTAAAACGTGC
+TGAGTGCTGATCCCGCGCGCCTCGCATAACTTCGAATTCTTCGCCGAAGTGTGCCAGCAG
+ATGAACGGCAAGACCTATCCGGTTGACGATAAAATGCTCAATTATACGCTGGTGCAGCCC
+GTCGGCGTCTGCGCGCTGGTGTCGCCGTGGAACGTGCCGTTTATGACCGCGACTTGGAAA
+GTTGCGCCGTGCCTGGCGCTGGGTAACACCGCGGTGCTCAAAATGTCCGAGCTGTCGCCG
+CTGACTGCCGACAGGCTGGGCGAGCTGGCACTGGAGGCAGGAATTCCGGCAGGCGTGCTG
+AACGTGGTGCAGGGCTACGGCGCGACGGCGGGCGATGCGCTGGTACGCCACCATGACGTG
+CGTGCGGTGTCGTTTACCGGCGGTACCGCCACCGGTCGCAATATCATGAAAAATGCCGGG
+CTGAAAAAATACTCGATGGAGCTGGGCGGCAAATCGCCGGTGCTGATTTTTGAAGACGCC
+GACATTGAGCGCGCGCTGGACGCCGCGCTGTTCACCATCTTCTCGATCAACGGCGAACGC
+TGCACCGCTGGGTCGCGCATCTTTATCCAGCAGAGCATTTACCCTGAGTTCGTGAAGCGC
+TTTGCCGAACGCGCGAATCGCCTGCGTGTCGGCGATCCGACCGACCCGAACACCCAGGTC
+GGCGCGCTGATTAGCCAACAGCACTGGGAGAAAGTCTCCGGTTATATCCGCCTCGGCATT
+GAAGAGGGGGCAACGCTGCTGGCGGGCGGTGCGGAAAAACCCACTGACCTGCCTGCGCAT
+CTGAAAGGCGGTAACTTCCTGCGCCCAACCGTGCTGGCCGATGTCGACAACCGTATGCGC
+GTTGCGCAGGAAGAGATCTTTGGGCCGGTCGCCTGCCTGCTGCCATTCAAAGACGAAGCG
+GAAGGGTTACGTTTGGCGAACGATGTGGAATACGGTCTGGCCTCTTATATCTGGACCCAG
+GACGTGAGCAAAGTGTTGCGCCTGGCGCGTGGGATTGAAGCCGGCATGGTCTTCGTCAAC
+ACCCAGAACGTCCGCGACCTGCGCCAGCCGTTCGGCGGCGTGAAAGCCTCCGGTACCGGG
+CGCGAAGGCGGCGAATATAGCTTCGAAGTGTTTGCGGAAATGAAAAACGTCTGCATCTCA
+ATGGGCGACCATCCTATCCCAAAATGGGGAGTTTGAATGCCGCACTTTATTGCTGAATGT
+ACTGAAAATATTCGCGAGCAGGCTGATTTACCAAGCCTGTTCAGCAAGGTAAACGAGGCG
+CTGGCCGCCACCGGGATTTTCCCCATCGGCGGTATCCGCAGTCGCGCCCACTGGCTGGAT
+ACCTGGCAGATGGCTGACGGTAAGCATGATTACGCGTTTGTGCATATGACGCTGAAAATC
+GGCGCCGGGCGCAGCCTGGAGAGCCGTCAGGAAGTCGGCGAAATGCTGTTTGGGCTGATT
+AAAGCCCACTTCGCCGACCTGATGGAGAACCGCTATCTGGCGCTGTCGTTTGAGATTGCC
+GAGTTACATCCAACGCTCAATTACAAACAAAACAACGTACACGCGTTATTTAAATAGATG
+CTCGATAAACAGACCCATACCCTGATCGCTCAGCGACTTAATCAGGCTGAAAAACAGCGT
+GAACAGATTCGCGCAGTGTCGCTGGATTATCCCAACATCACTATTGAAGATGCCTATGCC
+GTACAGCGTGAATGGGTCAATATCAAGATTGCCGAAGGGCGCACGCTCAAAGGCCACAAA
+ATCGGCCTGACCTCAAAAGCGATGCAGGCCAGCTCGCAAATCAGCGAACCGGATTACGGC
+GCGCTGCTTGACGATATGTTCTTCCATGACGGCGGAGATATCCCCACCGACCGTTTTATC
+GTCCCGCGTATTGAAGTGGAGCTGGCGTTCGTGCTGGCGAAACCGCTGCGCGGCCCTCAC
+TGCACGCTGTTCGACGTCTACAACGCCACGGATTATGTGATTCCGGCGCTGGAACTGATT
+GACGCCCGCAGCCACAACATCGACCCGGAAACCCAGCGCCCGCGCAAAGTGTTCGACACC
+ATTTCCGACAACGCCGCCAACGCCGGGGTGATCCTCGGTGGTCGCCCCATCAAACCAGAC
+GAGCTGGATCTGCGCTGGATCTCCGCGCTGCTCTATCGCAACGGCGTGATCGAAGAAACC
+GGCGTCGCCGCAGGCGTGCTGAATCATCCGGCCAACGGCGTGGCGTGGCTGGCGAACAAG
+CTTGCCCCCTACGATGTCCAGCTTGAAGCCGGGCAGATCATCCTCGGCGGCTCGTTCACC
+CGCCCGGTGCCGGCGCGCAAGGGCGACACCTTCCATGTCGATTACGGCAACATGGGCGCG
+ATCAGTTGCCGGTTTGTGTAAATGAGCTCTGTACCCGCGCCGCGTGAATATTTTCTTGAC
+TCTATCCGCGCATGGCTGATGTTGTTAGGGATTCCCTTTCATATCTCGTTGATCTATTCC
+ACTCACAGTTGGCATGTCAATAGCGCCGCGCCATCGTGGTGGCTAACCCTGTTTAACGAT
+TTTATCCACGCTTTTCGTATGCAGGTGTTTTTTGTTATTTCTGGTTATTTTTCGTACATG
+TTATTTTTACGTTATCCATTAAAACACTGGTGGAAAGTACGGGTAGAACGTGTGGGTATT
+CCCATGCTTACCGCAATCCCTTTGCTTACCTTGCCGCAATTTATCCTGTTGCAATATGTC
+AAAGAGAAAACAGAGAACTGGCCTACACTCTCTGCCTATGAAAAATATAATACGTTAGCG
+TGGGAACTCATTTCACATCTGTGGTTTTTACTGGTGCTGGTGATATTAACCACCGTCAGC
+ATCGGGATTTTTACCTGGTTCCAAAAAAGGCAGGAAACAAGCAAGCCTCGTCCCGCCGCT
+ATTTCGCTGGCCAAACTTTCGCTTATTTTTTTCCTGCTGGGGGTGGCGTACGCTGCTATC
+AGGCGCATTATATTCATCGTATATCCGGCAATCCTCAGTGACGGCATGTTCAATTTTATT
+GTGATGCAAACGCTATTTTATGTGCCGTTTTTTATTCTCGGCGCGTTGGCCTTCATTCAC
+CCCGATCTGAAAGCGCGCTTCACCACGCCCTCACGCGGATGCACTTTAGGCGCTGCCGTT
+GCTTTTATCGCGTATCTGCTGAATCAACGTTATGGGAGCGGCGACGCCTGGATGTACGAA
+ACCGAATCCGTGATTACGATGGTAATGGGGCTATGGATGGTGAACGTGGTATTTTCACTG
+GGGCATCGCTTGTTAAACTTTCAGTCCGCGCGTGTCACCTATTTCGTGAATGCTTCGCTG
+TTTATTTATCTGGTGCATCATCCCTTAACGCTTTTCTTTGGCGCGTATATTACACCGCAT
+ATCTCCTCCAACCTGATCGGGTTCTTGTGCGGGCTGATATTTGTTATGGGTATTGCGTTA
+ATTCTGTATGAAATTCATTTACGCATCCCGCTCCTGAAATTTCTCTTTTCAGGTAAACCG
+CCGGTAAAACAAGAAAGCCGCGCCGCGATCGGGTAGATGAAACATAAACGACAAATGATG
+AAAATGCGTTGGTTGGGCGCAGCTATTATGTTAACGCTCTACGCATCATCGAGCTGGGCG
+TTCAGTATTGATGACGTGGCAAAACAAGCTCAATCTTTAGCCGGGAAAGGCTATGAGGCG
+CCTAAAAGCAACTTGCCCTCCGTTTTCCGCGACATGAAATATGCGGATTATCAGCAGATC
+CAGTTTAACAGCGATAAAGCCTACTGGAACAACTTAAAGACCCCTTTTAAGCTCGAATTT
+TACCATCAGGGGATGTACTTCGATACGCCGGTCAAGATTAACGAAGTGACGGCGACGACG
+GTCAAAAGAATCAAATACAGCCCGGATTACTTCAATTTTGGCAATGTTCAGCACGATAAA
+GACACGGTAAAAGATTTAGGCTTCGCCGGGTTCAAAGTCCTGTACCCCATTAACAGTAAA
+GATAAGAACGACGAAATCGTCAGTATGCTTGGCGCCAGCTATTTCCGCGTTATCGGCGCA
+GGCCAGGTGTATGGCTTATCTGCGCGCGGCCTGGCGATTGATACCGCCTTACCATCTGGT
+GAAGAGTTTCCCCGCTTTCGCGAGTTCTGGATTGAGCGTCCAAAACCCACCGATAAGCGT
+TTGACCGTCTATGCATTACTGGATTCTCCGCGCGCGACCGGCGCTTACCGTTTTGTGATC
+ATTCCTGGCCGCGATACCGTGGTGGACGTGCAGTCAAAAGTCTATCTGCGCGATAAGGTG
+GGCAAGCTGGGCGTTGCGCCATTAACCAGTATGTTCCTGTTTGGGCCAAACCAGCCGTCG
+CCGACGACCAACTATCGTCCGGAATTGCATGACTCGAACGGCTTATCCATTCATGCGGGT
+AATGGCGAGTGGATTTGGCGTCCGCTGAACAATCCAAAACACCTCGCTGTGAGCAGCTAT
+GCGATGGAAAACCCTCAGGGATTCGGCCTGTTGCAGCGTGGTCGCGAGTTCTCGCGCTTT
+GAAGATTTAGACGATCGCTATGACCTGCGTCCAAGCGCCTGGATTACCCCGAAAGGCGAC
+TGGGGCAAAGGTAAGGTTGAACTGGTTGAAATTCCGACCAATGATGAAACCAACGATAAC
+ATCGTCGCTTACTGGACTCCGGATCAACTGCCGGAACCGGGTAAAGAGATGAACTTCAAG
+TACACTCTGACCTTCAGCCGCGATGAAGATAAACTTCATGCGCCGGATAATGCCTGGGTG
+CTGCAAACACGCCGCTCAACGGGCGACGTTAAACAGTCGAATCTGATTCGCCAGCCCGAC
+GGCACTATTGCCTTTGTGGTGGATTTCGTTGGCGCCGACATGAAAAAACTGCCGCCGGAT
+ACGCCCGTCGCTGCACAAACCAGCATTGGCGATAACGGTGAAATCGTTGACAGTAATGTA
+CGCTATAACCCAGTCACTAAAGGCTGGCGTTTAATGCTGCGCGTGAAAGTCAAAGACGCG
+AAGAAAACCACGGAAATGCGTGCCGCATTGGTGAATGCCGATCAGACGCTAAGTGAAACC
+TGGAGCTACCAGTTACCTGCCAATGAATAAATGAATAAAACAACTGAGTATATTGACGCA
+CTGCTGCTTTCTGAACGTGAGAAAGCGGCATTGCCGAAAACTGACATCCGCGCCGTGCAT
+CAGGCGCTGGATGCCGAGCATCGGACTTACTCGCGAGAAGACGATTCACCGCAGGGTTCC
+GTAAAAGCCCGCCTTGAACACGCCTGGCCGGATTCATTGGCGAAGGGGCAGTTAATTAAA
+GATGATGAAGGGCGCGATCAGTTGCAGGCTATGCCAAAAGCGACGCGCTCTTCGATGTTT
+CCTGATCCCTGGCGAACCAACCCGGTTGGCCGTTTCTGGGATCGCCTGCGTGGGCGGGAT
+GTAACGCCGCGCTATGTTTCTCGTCTGACAAAAGAAGAGCAGGCGAGTGAGCAAAAATGG
+CGTACCGTCGGCACTATACGCCGCTATATTTTGTTAATTTTGACTCTGGCGCAAACCGTC
+GTCGCGACCTGGTATATGAAGACCATTCTGCCCTATCAGGGATGGGCGCTCATCAATCCT
+ATGGATATGGTGGGGCAGGATATTTGGGTCTCCTTTATGCAGCTCCTGCCCTACATGCTG
+CAAACCGGTATCCTGATTTTGTTTGCCGTGCTGTTCTGCTGGGTGTCTGCCGGATTCTGG
+ACGGCGCTGATGGGCTTCCTGCAACTGCTTATCGGGCGCGATAAGTACAGTATCTCCGCG
+TCTACGGTTGGCGATGAGCCCCTCAATCCGGAACACCAGACGGCGCTGATCATGCCTATC
+TGTAATGAAGACGTTAGCCGCGTTTTCGCCGGTCTGCGCGCGACCTGGGAGTCCGTTAAA
+GCCACAGGCAACGCCGCGCATTTTGACGTCTATATCCTTAGCGATAGTTATAACCCGGAT
+ATCTGCGTGGCGGAGCAAAAGGCGTGGATGGAGCTCATCGCGGAAGTGCAGGGCGAAGGC
+CAAATTTTTTACCGTCGCCGCCGCCGCCGTATGAAACGCAAAAGCGGCAATATTGACGAT
+TTTTGCCGCCGCTGGGGCAATCAGTACAGCTATATGGTGGTGCTGGACGCGGACTCAGTG
+ATGAGCGGCGAGTGTCTGAGCGGGCTGGTGCGCCTGATGGAAGCGAACCCTAACGCCGGG
+ATTATCCAGTCTTCGCCGAAAGCGTCGGGGATGGATACTCTGTATGCCCGCTGCCAACAG
+TTCGCGACCCGTGTTTATGGACCGCTGTTTACCGCCGGGCTGCACTTCTGGCAGTTGGGG
+GAGTCGCACTACTGGGGGCACAATGCCATTATCCGCGTGAAGCCGTTTATCGAGCACTGC
+GCTCTGGCGCCGCTGCCGGGAGAAGGTTCGTTCGCCGGATCGATTCTTTCCCACGACTTT
+GTGGAGGCGGCGCTAATGCGTCGGGCAGGGTGGGGCGTCTGGATTGCCTACGATCTCCCC
+GGCTCCTATGAAGAGCTGCCGCCAAACCTGCTGGATGAGCTTAAACGCGACCGCCGCTGG
+TGTCACGGCAACCTGATGAACTTTCGTCTGTTCCTGGTGAAAGGAATGCACCCGGTGCAT
+CGCGCCGTGTTCCTGACCGGGGTAATGTCATACCTGTCCGCGCCGTTATGGTTTATGTTC
+CTCGCGCTTTCTACCGCGCTGCAGGTCGTTCATGCGTTAACAGAGCCGCAATATTTCCTT
+CAGCCGCGCCAGCTTTTTCCGGTCTGGCCGCAGTGGCGTCCGGAACTGGCAATCGCGCTG
+TTTGCGTCAACGATGGTGCTGCTGTTCCTGCCGAAGCTGCTCAGTATTATGCTGATCTGG
+TGTAAAGGCACCAAAGAGTATGGCGGTTTCTGGCGCGTTACGCTGTCGCTATTGCTGGAA
+GTGCTGTTCTCCGTGTTGCTGGCGCCGGTGCGTATGCTGTTTCATACCGTGTTTGTGGTC
+AGCGCGTTCCTCGGCTGGGAAGTGGTCTGGAACTCACCGCAACGCGACGATGATTCTACG
+CCGTGGGGAGAAGCCTTTATGCGTCACGGCTCTCAACTGCTGCTGGGGCTGGTCTGGGCG
+GTGGGTATGGCGTGGCTGGATTTACGCTTTCTGTTCTGGCTGGCGCCGATTGTCTTTTCG
+CTGATTCTGTCGCCATTTGTTTCGGTGATCTCCAGTCGTTCAACGGTAGGATTACGCACC
+AAACGCTGGAAGCTGTTCCTGATCCCGGAAGAGTATTCGCCGCCTCAGGTGTTGGTCGAT
+ACCGATAAATATCTGGAGATGAATCGCCGCCGTATTCTGGACGATGGCTTTATGCATGCG
+GTATTTAACCCGTCGCTTAATGCGCTGGCGACCGCGATGGCCACCGCGCGTCACCGCGCC
+AGTAAGGTGCTGGAAATAGCCCGCGATCGTCATGTGGAGCAGGCGCTAAACGAAACGCCG
+GAGAAACTGAACCGCGATCGGCGTCTGGTTTTGCTCAGCGATCCGGTGACGATGGCGCGT
+TTACACTATCGGGTCTGGAATGCGCCAGAGAGATACTCTTCCTGGGTAAACCATTATCAG
+TCTCTCGTCCTGAATCCGCAGGCGTTGCAGGGACGAACATCGTCAGCGGGAATGTCGCGC
+GTCTCGCAGGCGAGGAACCTGGGTAAATATTTTCTTCTCATCGATAACATGTTAGTGGTG
+CTGGGTTTTTTCGTCGTCTTCCCGCTCATCTCTATTCGCTTTGTCGATCAAATGGGGTGG
+GCTGCCGTAATGGTAGGGATCGCGCTCGGCCTGCGTCAGTTTATTCAACAAGGTCTGGGC
+ATTTTTGGCGGCGCCATCGCCGATCGCTTTGGCGCGAAACCGATGATTGTCACCGGTATG
+CTGATGCGCGCCGCAGGCTTTGCCACCATGGGTATCGCGCATGAGCCCTGGCTCTTGTGG
+TTTTCCTGCTTTCTTTCCGGTCTCGGCGGTACGCTTTTCGACCCGCCGCGTTCAGCGCTG
+GTGGTCAAATTAATTCGTCCGGAGCAACGGGGCCGCTTCTTCTCTCTGTTGATGATGCAG
+GACAGCGCGGGCGCGGTGATTGGCGCGCTGCTGGGAAGCTGGTTGCTACAATACGATTTT
+CGCCTGGTCTGCGCGACGGGCGCTATTTTGTTCATATTATGCGCCCTTTTCAACGCATGG
+CTGCTTCCGGCCTGGAAGCTATCAACGGCCAGAACGCCGGTGCGTGAAGGAATGCGCCGC
+GTCATGAGCAATAAAAGGTTTGTCACCTACGTGCTGACGCTGGCGGGCTACTATATGCTG
+GCGGTACAGGTCATGTTAATGCTGCCGATTATGGTAAACGATATCGCCGGTTCGCCTGCT
+GCCGTGAAATGGATGTACGCTATTGAGGCGTGTCTCTCGCTGACGTTGCTCTACCCGATT
+GCCCGCTGGAGCGAAAAGCGTTTTCGGCTGGAGCATCGGCTGATGGCCGGTTTGCTCGTC
+ATGTCGCTGAGCATGCTCCCCATCGGGATGGTGGGCAATTTACAGCAGCTTTTTACGCTT
+ATTTGCGCTTTCTACATCGGCTCGGTTATCGCCGAACCGGCGCGCGAAACGCTCAGCGCG
+TCGCCCGCGGACGCGAGGGCGCGGGGAAGCTATATGGGCTTTAGCCGTCTGGGATTAGCC
+ATTGGCGGCGCGATTAGTTATATCGGCGGCGGCTGGTTGTTTGATATGGGTAAAGCGCTT
+GCGCAGCCTGAACTACCGTGGATGATGCTCGGTATTATCGGCTTTATCACCTTTTTGGCT
+TTAGGCTGGCAATTTAGTCATAAGCGCACGCCGCGCCGGATGCTGGAACCCGGCGCCATG
+ACCATGTATGCCACGCTGGAAGAAGCTATCGATGCAGCCCGGGAAGAATTTCTGGCTGAC
+CATCCAGGCCTCGAACAAGACGAAGCGAATGTGCAGCAGTTCAACGTTCAGAAATATGTA
+CTGCAGGATGGGGACATCATGTGGCAGGTCGAATTTTTCGCCGATGAAGGTGAAGATGGC
+GAATGTCTGCCGATGCTGAGTGGTGAAGCCGCACAGAGCGTGTTTGACGGCGATTATGAT
+GAGATAGAGATCCGCCAGGAATGGCAGGAAGAGAATACTTTGCATGAATGGGATGAAGGG
+GAATTCCAGCTTGAACCCCCGCTTGATACCGAGGAAGGCCGTACTGCGGCAGACGAATGG
+GATGAGCGTATGTCACTATTAGCCAGGCTGGAACAAAGTGTACACGAAAACGGTGGGCTG
+ATTGTCTCATGCCAACCGGTACCAGGCAGCCCTATGGATAAACCTGAAATTGTGGCTGCA
+ATGGCACAGGCAGCGGCTTCGGCGGGTGCGGTCGCTGTGCGCATTGAAGGCATTGAGAAT
+CTGCGGACTGTTCGTCCCCATCTTTCTGTTCCTATTATTGGGATAATTAAACGTGACCTT
+ACAGGGTCGCCAGTCCGTATCACTCCATATTTACAGGATGTTGACGCCCTGGCGCAGGCA
+GGTGCCGATATTATCGCTTTTGATGCCTCATTCCGCTCTCGCCCGGTTGATATTGATAGT
+TTACTGACACGTATTCGCCTGCATGGATTACTGGCGATGGCAGACTGTTCAACCGTGAAT
+GAAGGCATAAGTTGCCATCAGAAAGGAATCGAATTCATTGGTACAACACTGTCTGGCTAT
+ACCGGTCCCATCACGCCGGTTGAGCCAGATTTGGCAATGGTGACACAACTGAGTCATGCA
+GGTTGTCGTGTTATTGCCGAGGGGCGCTATAACACGCCTGCACTGGCGGCCAATGCTATT
+GAGCATGGTGCCTGGGCAGTTACCGTTGGTTCCGCTATCACCCGTATCGAGCATATCTGT
+CAGTGGTTCAGTCACGCAGTAAAACGCTGAATGAAAAATTTTAAGAAAATGATGACGCTA
+ATGGCGCTATGTTTATCAGTTGCTATCACCACATCAGGATATGCAACCACGCTTCCTGAT
+ATACCAGAACCACTGAAAAATGGTACTGGCGCTATTGATAATAATGGCGTGATTTATGTC
+GGCTTAGGTACCGCAGGGACATCCTGGTATAAAATTGATCTTAAAAAGCAACATAAAGAC
+TGGGAGCGTATAAAGTCGTTTCCTGGTGGAGCTCGTGAGCAATCCGTGTCGGTATTTTTA
+AATGATAAGCTGTATGTTTTTGGTGGCGTAGGGAAAAAAAACAGTGAATCACCGTTGCAG
+GTTTATAGCGATGTGTACAAATACTCACCGGTGAAAAATACATGGCAAAAAGTTGATACT
+ATATCTCCAGTTGGATTAACAGGGCATACGGGAGTAAAATTAAACGAAACGATGGTACTT
+ATTACCGGAGGGGTTAATGAGCATATCTTTGATAAGTATTTTATTGATATAGCGGCTGCG
+GATGAAAGTGAAAAAAATAAAGTCATCTATAATTATTTTAATAAACCTGCCAAAGATTAT
+TTTTTTAATAAAATCGTATTTATCTACAATGCTAAAGAGAACACATGGAAGAATGCCGGT
+GAGCTGCCAGGCGCGGGGACGGCAGGATCGTCATCGGTAATGGAAAATAATTTCTTGATG
+CTGATTAATGGTGAGCTCAAACCGGGTTTACGTACCGATGTGATTTACCGCGCCATGTGG
+GATAACGATAAGCTAACATGGTTGAAGAACAGCCAGTTACCGCCATCGCCTGGAGAACAA
+CAGCAGGAAGGGTTGGCCGGAGCATTTTCGGGCTATAGCCACGGTGTCCTGCTTGTCGGT
+GGTGGCGCGAATTTTCCGGGAGCAAAACAAAATTATACTAATGGAAAGTTTTATTCCCAC
+GAAGGGATAAATAAAAAATGGCGAGATGAAGTCTATGGTTTGATTAATGGCCATTGGCAA
+TATATGGGTAAAATGAAACAACCTCTCGGCTATGGTGTATCAGTAAGTTATGGTGATGAA
+GTTTTCCTTATTGGTGGTGAAAATGCTAAAGGGAAACCTGTTTCGTCTGTAACCTCCTTT
+ACCATGCGTGATGGTAATTTATTAATAAAATAAGTGATAGCAAAATTCTTCCCGTGGTAT
+AGCGAGATAACACGTCCACAAAAAAATGCTTTATTTTCAGCATGGCTGGGTTACGTTTTT
+GATGGCTTCGACTTTATGCTGATTTTCTACATTATGTATCTGATCAAGGCTGACTTAGGA
+TTGACAGATATGGAGGGCGCATTCCTTGCCACAGCGGCCTTTATTGGGCGACCATTTGGC
+GGGGCGCTATTTGGTCTGCTGGCAGACAAATTTGGCCGTAAGCCGTTAATGATGTGGTCG
+ATAGTTGCCTATTCTGTAGGTACAGGGTTAAGTGGCCTGGCTTCCGGTGTAATTATGCTG
+ACGCTTAGTCGTTTTATTGTCGGTATGGGGATGGCGGGGAAGTATGCTTGCGCTTCTACT
+TATGCCGTGGAAAGTTGGCCAAAGCATTTAAAATCTAAAGCGAGCGCATTTCTGGTTTCA
+GGTTTCGGTATTGGTAACATCATAGCAGCCTATTTTATGCCGTCATTTGCCGAAGCGTAT
+GGTTGGCGTGCTGCTTTTTTTGTCGGTTTGCTACCCGTTCTTTTAGTAATCTACATCCGG
+GCCAGGGCTCCTGAATCTAAAGAGTGGGAAGAAGCCAAACTCAGTGGTCTCGGAAAGCAT
+TCACAAAGTGCCTGGTCAGTTTTCTCTTTGTCAATGAAAGGGCTATTTAATCGAGCTCAA
+TTTCCACTGACATTATGTGTATTTATTGTTCTGTTCTCTATTTTCGGCGCAAACTGGCCG
+ATCTTTGGTCTACTGCCTACATATTTGGCGGGAGAGGGCTTTGATACGGGCGTGGTCTCT
+AATTTAATGACGGCGGCGGCATTCGGCACTGTATTGGGAAATATCGTTTGGGGTCTGTGC
+GCAGATAGAATTGGTTTGAAGAAAACGTTCAGCATTGGTCTTCTCATGTCCTTTTTATTC
+ATTTTCCCGTTATTCAGAATTCCGCAAGATAATTATTTACTGCTGGGCGCATGTTTATTC
+GGTTTAATGGCGACTAACGTAGGTGTTGGCGGGCTGGTTCCCAAATTTCTCTACGACTAC
+TTTCCTCTTGAGGTTCGTGGTTTGGGTACCGGGCTTATTTATAATCTTGCTGCGACATCA
+GGCACATTCAATTCAATGGCGGCGACCTGGCTTGGAATAACAATGGGGCTAGGCGCTGCG
+CTAACGTTCATTGTTGCTTTCTGGACCGCAACAATTCTACTCATTATTGGCCTATCCATT
+CCGGATAGACTAAAAGCACGTCGTGAAAGGTTTCAGTCAACAAAAGAATTTTAAATGAAA
+AAGTATCTTGCTTTCGCCGTTACGCTGCTGGGTATGGGTAAAGTCATCGCCTGTACTACC
+CTTTTGGTAGGCAATCAGGCTTCGGCTGACGGCTCCTTTATTATCGCGCGCAACGAGGAT
+GGCTCGGCAAATAACGCCAAGCATAAGGTTATTCATCCCGTCGCGTTTCATCAACAAGGC
+GAGTATAAAGCACATCGCAACAATTTTAGCTGGCCGCTTCCGGAGACAGCGATGCGCTAT
+ACGGCGATTCATGACTTTGATACTAACGATAACGCCATGGGTGAAGCCGGTTTCAATTCG
+GCGGGCGTCGGAATGAGCGCAACGGAAACCATTTACAACGGCAGAGCGGCGCTGGCTGCC
+GATCCTTACGTGACAAAAACGGGAATCACGGAAGACGCCATTGAGTCCGTGATCCTGCCA
+GTGGCGCAATCGGCGCGTCAGGGCGCCAAATTACTGGGAGATATTATTGAACAAAAAGGC
+GCGGGCGAAGGTTTCGGCGTCGCGTTTATTGATAGCAAAGAGATATGGTATCTGGAGACG
+GGAAGCGGACATCAATGGCTGGCAGTACGACTTCCGGCAGATAGCTATTTCGTTTCCGCC
+AATCAGGGACGTTTACGCCATTACGATCCGAATGATAACGCGAATTATATGGCGTCACCA
+ACGTTAGTAAGCTTTGCGAAAAAGCAGGGATTATATGATCCGGCCCGCGGCGAATTCGAC
+TTTCATCAAGCCTATTCGCAGGATAACAAAAACGATACCACCTATAATTATCCGCGCGTC
+TGGACGCTACAACACCAGTTTAATCCGCATCTGGATACGGTCGTTAGCGAAGGGGAAACA
+TTTTCTGTTTTTTTAACGCCAATAACGAAGATCAGCGTGGCGGCAGTAAAAAACGCGTTA
+CGCAATCACTATCAGGGAACGTCGCACGACCCTTATGCCAGTCATAATCCACAAGAACCA
+TGGCGACCTATATCCGTTTTTCGTACCCAGGAGTCACATATTTTACAGGTCAGACCGAAA
+TTACCGCAGGCTATCGGCAACGTAGAATACATCGCCTATGGAATGCCATCTCTTAGCGTC
+TATCTCCCCTATTACCAGGGGATGCGTCATTATCAACCCGGAGATGATAAAGGAACCGAT
+CGGGCGAGCAACGACTCTACCTACTGGACATTCCGCACGCTGCAAACACTGGTTATGCAA
+GACTACAATACGTTTGCGCCAGATGTGCAACATGCCTGGAAAACATTTGAACAGCAAACA
+GCTAAGCAACAGTATAAGATGGAGCAGAGCTATCTGAGATTATATGCGTCGCATCCGAAA
+GAAGCACAACGCTTACTGCAAAATTTTGAAGATAAAACGATGCAAAATGCGCAGACGCTC
+GCCCGTCGCCTGACCAATAATATTATTACGACAATGACTTACCGCACAGATATGAAATAT
+CACTTTTCAAGTACGCAGCCATAAATGGGAAGACAAAAAGCAGTGATCAAAGCTCGTCGT
+GAAGCAAAGCGTGTGTTGAGACGAGATTCGCGTAGTCATAAGCAACGTGAAGAAGAATCG
+GTCACGTCACTGGTACAGATGGGCGGAGTAGAAGCCATTGGCATGGCGCGCGATAGTCGC
+GATACCTCTCCTGTTAAGGCGCGAAATGAAGCACAGGCGCATTATCTGAACGCTATCGAC
+AGTAAACAGCTTATTTTTGCGACCGGCGAAGCCGGCTGCGGAAAAACATGGATCAGTGCG
+GCAAAGGCGGCAGAAGCATTGATTCATAAGGACGTCGAGAGGATCATTGTGACGCGTCCG
+GTATTGCAGGCTGATGAAGATCTTGGTTTTTTGCCCGGTGATATCGCTGAAAAATTCGCG
+CCTTATTTTCGTCCCGTCTACGATGTCCTGCTTAAACGGTTGGGCGCGTCCTTTATGCAA
+TATTGTTTGCGCCCGGAAATCGGTAAGGTAGAAATTGCCCCGTTCGCCTATATGCGTGGG
+CGTACTTTTGAAAATGCGGTCGTGATCCTCGACGAGGCGCAAAATGTGACTGCGGCGCAA
+ATGAAAATGTTTTTGACGCGATTAGGCGAAAATGTCACGGTCATTGTCAATGGCGATATT
+ACGCAATGCGACCTGCCGCGCGGTGTGCGTTCCGGGTTGAGTGATGCGTTGGAACGCTTT
+GAAGAAGATGAAATGGTGGGGATTGTGCATTTCAACAAAGACGACTGCGTGCGCTCGGCG
+CTTTGTCAGCGAACGCTCCACGCATACAGCTAAATGGGAACCACCACGATGGGGGTTAAG
+CTGGACGACGCCACGCGCGAACGGATCAAAATGGCCGCGTCGCGTATCGATCGCACGCCG
+CACTGGTTAATAAAACAGGCAATCTTTAGCTATCTGGACAAGCTGGAAAATAGCGATACG
+CTACCGGAGCTACCTGCGCTGTTTGCCGGCGCGGCAAATGAAAGCGAGGAGCCGGTCGCG
+CCGCAGGATGAGCCGCATCAGCCCTTTCTGGAGTTTGCCGAACAGATTCTTCCCCAATCC
+GTCTCTCGCGCCGCCATCACCGCCGCCTGGCGCCGCCCGGAAACCGATGCGGTGTCAATG
+CTAATGGAACAGGCGCGCCTGTCGCCGCCTGTCGCTGAGCAGGCGCATAAACTGGCGTAT
+CAACTGGCGGAGAAATTGCGCAATCAAAAATCCGCCAGCGGTCGCGCGGGTATGGTGCAA
+GGCCTGTTGCAGGAGTTTTCCCTCTCTTCGCAAGAAGGCGTAGCGCTGATGTGTCTGGCG
+GAAGCGCTGCTGCGTATTCCCGACAAAGCTACGCGCGATGCGTTAATTCGCGACAAAATC
+AGTAATGGCAACTGGCAGTCGCATATTGGCCGTAGCCCGTCGCTGTTTGTAAACGCCGCC
+ACCTGGGGGCTGCTCTTTACCGGCCGACTGGTCTCAACGCATAACGAAGCCAATCTTTCG
+CGCTCGCTGAACCGCATTATCGGCAAGAGCGGCGAACCGTTAATCCGCAAAGGCGTCGAC
+ATGGCGATGCGTTTAATGGGCGAGCAGTTCGTGACTGGCGAAACCATTGCTCAGGCGCTG
+GCGAATGCCCGAAAACTGGAAGAGAAAGGGTTCCGCTATTCTTACGATATGCTGGGCGAA
+GCCGCGTTAACCGCCGCCGATGCGCAGGCCTATATGGTCTCTTACCAGCAAGCGATTCAT
+GCCATCGGCAAAGCGTCTAACGGTCGCGGTATTTACGAAGGGCCAGGCATCTCGATTAAG
+CTGTCCGCCCTGCATCCACGCTATAGTCGCGCGCAATACGATCGGGTAATGGAGGAGCTT
+TATCCGCGCCTGAAATCCCTGACGCTGCTGGCGCGCCAGTATGATATCGGTCTCAATATC
+GACGCCGAAGAGGCGGATCGTCTGGAGATCTCGCTTGATCTGCTGGAAAAACTCTGCTTC
+GAACCCGAACTGGCGGGCTGGAACGGCATTGGCTTTGTGATTCAGGCTTACCAGAAACGC
+TGCCCGCTGGTCATTGATTATTTAGTCGATCTGGCCTCCCGTAGCCGCCGTCGGCTGATG
+ATTCGTCTGGTGAAAGGCGCCTACTGGGATAGCGAGATCAAACGCGCGCAAATGGAAGGG
+CTGGAGGGCTATCCAGTTTATACCCGCAAAGTGTATACCGATGTCTCTTATCTGGCCTGC
+GCGAAAAAACTGCTCGCCGTCCCTAATCTGATCTACCCGCAGTTCGCGACCCATAACGCT
+CACACACTGGCGGCGATTTATCATCTGGCCGGGCAAAATTACTATCCGGGTCAGTACGAA
+TTCCAGTGCCTGCACGGCATGGGAGAACCGCTGTATGAACAGGTCACCGGTAAAGTGGGG
+GACGGAAAACTTAACCGTCCCTGCCGTATTTACGCGCCGGTGGGAACACACGAAACCCTG
+CTGGCCTATCTGGTACGACGCCTGCTGGAAAACGGCGCCAACACCTCTTTTGTCAACCGC
+ATCGCCGATGCCACCCTACCGCTCGATGAACTGGTGGCCGACCCGGTCGAGGCCGTGGAA
+AAACTGGCGCAGCAGGAAGGTCAGGCTGGCATACCGCATCCAAAAATTCCGCTGCCGCGC
+GATCTGTACGGCGAAGGTCGGATAAACTCCGCCGGACTTGATTTAGCGAATGAACATCGC
+CTCGCCTCGCTTTCTTCTGCCCTGTTAAGCAACGCCATGCAGAAATGGCAGGCCAAACCT
+GTGCTGGAACAACCGGTGGCCGACGGTGAGATGACGCCGGTTATCAACCCGGCGGAACCG
+AAAGATATTGTTGGCTGGGGACGCGAAGCGACAGAAAGCGAGGTTGAACAGGCGTTGCAA
+AACGCGGTCAATCAGGCGCCGGTTTGGTTTGCGACGCCGCCGCAAGAACGCGCCGCTATT
+TTGCAGCGGGCGGCGGTATTGATGGAAGACCAAATGCAGCAGTTGATTGGCCTGTTGGTG
+CGTGAAGCGGGGAAAACGTTCAGCAACGCCATTGCCGAAGTGCGCGAAGCGGTAGACTTC
+CTCCATTATTATGCCGGTCAAGTGCGTGACGATTTCGATAACGAAACGCATCGCCCGTTA
+GGGCCGGTGGTCTGTATCAGTCCGTGGAACTTTCCGCTGGCCATTTTCACTGGCCAAATC
+GCCGCCGCGCTGGCGGCAGGTAACAGCGTTCTGGCGAAACCGGCAGAGCAGACATCGCTG
+ATTGCCGCCCAGGGCATTGCCATTTTGCTGGAAGCGGGCGTACCGCCGGGCGTCGTGCAA
+CTGTTGCCGGGACGGGGAGAAACCGTCGGCGCCCAGCTTACCGCCGATGCGCGTGTACGC
+GGCGTGATGTTTACCGGTTCCACGGAGGTCGCGACGTTGTTGCAGCGCAACATCGCCACG
+CGTCTTGACGCCCAGGGGCGCCCTATTCCGTTGATTGCGGAAACCGGCGGTATGAACGCT
+ATGATTGTCGACTCTTCCGCGCTCACCGAGCAGGTGGTCGTGGATGTGCTGGCTTCCGCC
+TTCGACAGCGCCGGACAACGCTGTTCCGCGCTCCGCGTGCTGTGTTTGCAGGACGATATC
+GCCGAACATACGCTGAAAATGTTACGCGGCGCGATGGCGGAGTGTCGGATGGGGAATCCA
+GGCCGTCTGACGACCGATATCGGGCCGGTGATCGATAGCGAGGCCAAAGCCAACATTGAA
+CGTCATATCCAGACGATGCGCGCCAAAGGCCGCCCGGTTTTCCAGGCCGCGCGTGAAAAC
+AGCGATGACGCGCAGGAATGGCAGACCGGTACGTTTGTTATGCCCACGCTTATTGAGCTG
+GAAAACTTCGCAGAACTGGAAAAAGAGGTCTTCGGGCCCGTGCTGCACGTCGTGCGTTAT
+AACCGTAACCAACTGGCGGAGCTTATCGAACAGATTAACGCTTCCGGCTACGGGCTAACG
+CTGGGCGTACATACCCGTATTGATGAAACCATTGCGCAAGTCACCGGTTCCGCCCATGTC
+GGCAACCTGTACGTTAACCGTAATATGGTGGGCGCGGTCGTCGGCGTCCAGCCGTTTGGC
+GGCGAAGGCCTGTCCGGCACCGGGCCAAAAGCGGGAGGGCCGCTCTATCTCTACCGCCTG
+CTGGCACACCGCCCGCCCAATGCGCTCAATACGACGCTGACTCGTCAGGATGCGCGTTAC
+CCGGTGGATGCGCAGCTTAAAACCACGCTACTCGCGCCGTTGACCGCTCTGACGCAATGG
+GCGGCGGATCGCCCGGCGCTACAGACGCTCTGCCGACAATTCGCCGATCTGGCGCAGGCC
+GGCACGCAGCGCCTGCTACCGGGGCCGACCGGCGAGCGTAATACCTGGACGCTGTTGCCG
+CGTGAACGGGTGTTATGCCTGGCTGATGATGAACAGGACGCGTTGACGCAGCTTGCCGCC
+GTTCTCGCCGTCGGCAGTCAGGCGCTATGGTCAGACGACGCCTTCCACCGCGATCTGGCG
+AAACGTCTCCCCGCCGCCGTCGCGGCGCGTGTCCAGTTTGCGAAAGCGGAAACGCTGATG
+GCGCAGCCGTTTGACGCGGTGATTTTCCACGGCGACTCCGACAAGCTGCGAACCGTGTGC
+GAAGCCGTCGCCGCCCGCGAAGGCGCGATAGTGTCGGTACAGGGGTTCGCCCGCGGCGAA
+AGCAATATGCTGCTGGAACGGCTCTATATTGAACGTTCGCTGAGCGTAAACACTGCCGCC
+GCTGGCGGTAATGCCAGCCTGATGACAATTGGCTAAATGGCTATTAGCACACCGATGTTG
+GTGACATTCTGTGTCTATATTTTTGGCATGATATTGATTGGGTTTATCGCCTGGCGCTCA
+ACCAAAAACTTTGATGACTATATTCTTGGCGGTCGCAGCCTGGGGCCGTTTGTTACGGCT
+TTATCAGCCGGCGCGTCGGATATGAGCGGCTGGCTGTTAATGGGGCTGCCTGGCGCTATC
+TTTCTGTCGGGGATCTCTGAAAGCTGGATCGCCATTGGCCTGACGTTAGGCGCATGGATT
+AACTGGAAGCTGGTGGCCGGGCGCCTGCGCGTGCATACCGAATTTAACAATAACGCGCTC
+ACGCTGCCGGACTATTTTACCGGTCGGTTTGAGGATAAGAGCCGAGTCCTGCGTATTATT
+TCCGCGCTGGTCATTCTGCTGTTTTTCACTATCTATTGCGCATCAGGTATTGTCGCTGGG
+GCACGACTGTTCGAAAGCACCTTCGGTATGAGCTATGAAACCGCACTGTGGGCGGGGGCC
+GCGGCAACCATTATTTATACCTTTATCGGCGGGTTTCTTGCCGTTAGCTGGACGGATACC
+GTTCAGGCCAGCCTGATGATTTTTGCGTTAATCCTGACGCCGGTGATGGTTATTGTCGGC
+GTAGGCGGTTTTAGCGAGTCGCTGGAAGTGATCAAGCAAAAGAGCATCGAGAATGTCGAC
+ATGCTCAAGGGGCTGAATTTTGTCGCTATTATTTCTCTGATGGGCTGGGGGCTGGGTTAC
+TTCGGTCAGCCGCATATCCTGGCGCGCTTTATGGCGGCGGATTCCCATCACAGTATTGTT
+CATGCGCGTCGTATCAGTATGACCTGGATGATTCTGTGTCTGGCGGGCGCGGTGGCGGTG
+GGCTTCTTTGGCATTGCGTACTTTAACAATAACCCCGCGCTGGCCGGGGCGGTGAACCAA
+AACTCAGAACGCGTATTTATTGAACTGGCGCAGATCCTGTTTAACCCGTGGATTGCCGGT
+GTTCTGCTGTCTGCTATCCTGGCGGCGGTGATGTCGACGTTGAGCTGTCAGTTGCTGGTA
+TGCTCCAGCGCGATTACGGAAGATTTATATAAGGCTTTTCTGCGTAAAAGCGCCAGCCAG
+CAAGAGCTGGTATGGGTAGGGCGAGTGATGGTGCTGGTGGTAGCGCTGATCGCCATTGCG
+CTGGCGGCGAATCCTGATAACCGTGTGCTGGGGCTGGTGAGCTACGCCTGGGCTGGATTC
+GGCGCGGCATTTGGACCTGTTGTCCTGTTTTCTGTGATGTGGTCGCGTATGACACGTAAC
+GGCGCGCTGGCGGGAATGATTATTGGCGCGGTGACGGTTATCGTCTGGAAACAATATGGC
+TGGCTGGATCTGTATGAGATTATCCCTGGCTTCATTTTCGGCAGCCTGGGGATCGTAATC
+TTTAGCCTGCTTGGCAAAGCGCCGACAGCAACGATGCAGGAACGCTTTGCAAAAGCGGAC
+GCGCATTATCATTCCGCGCCGCCGTCGAAGCTACAGGCGGAATAAATGGCGGGTAAACTG
+CGGCGTTGGCTGCGTGAAGCCGCGGTTTTTCTGGCGCTCCTCATCGCGATAATGGTGGTC
+ATGGACGTCTGGCGCGCGCCGCAGGCGCCTCCGGCGTTTGCCGCGACACCATTACATACG
+CTGACGGGAGAGTCGACAACTCTGGCGACCTTGAGCGAGGAACGCCCCGTACTGCTCTAT
+TTTTGGGCCAGCTGGTGCGGGGTATGCCGCTTTACCACGCCTGCGGTCGCTCACCTGGCG
+GCGGAAGGGGAAAACGTCATGACCGTTGCGCTCCGCTCCGGCGGTGATGCTGAGGTTGCC
+CGCTGGCTGGCGCGCAAGGGCGTTGACTTCCCGGTCGTCAATGATGCTAACGGCGCCTTA
+TCCGCTGGCTGGGAAATCAGCGTGACGCCAACGCTGGTGGTGGTTTCACAAGGTCGGGTT
+GTGTTCACCACCAGCGGCTGGACCAGCTATTGGGGCATGAAGCTTCGGCTGTGGTGGGCA
+AAAACGTTCTGAATGATGAAAAAAAGCGTCGCTATGCTGGCGGTTTGTATGCTGGCGCAA
+AGCCACCTTGCCATTGCTGCCGGTGCTCCTGCGCCTCAAGAGATCAACATTGTTTTACTG
+GGCACCAAAGGCGGGCCTTCTTTGCTCAATACAGCCAGACTACCGCAAGCGACGGCGCTC
+ACTATCGGCGATAAGATATGGCTGATAGATGCCGGCTACGGCGCCAGTCTGCAACTGGTG
+AAAAATGGCATTCCACTGCGCAACATCAATACTATTTTGCTCACCCATCTGCACAGCGAC
+CACATACTGGATTATCCTTCCTTGCTGATGAATGCCTGGGCAAGTGGCCTGAAAGACCAT
+ACCATACAGGTTTATGGCCCGCCGGGAACCCAGGCGATGACGAAGGCTAGCTGGAAGGTC
+TTTGACAGGGATATCACGTTACGCATGGAAGAAGAGGGGAAACCCGATCCGCGCAACCTG
+GTTAAGGCGACCGATATCGGCCAGGGCGTCATCTATAAAGATGAACTGGTCACAATAAGC
+GCGCTGAAAGTGCCTCATTCCCCTTTCCCGGACGGTGAAGCGTTTGCTTACCGTTTTGAT
+ACTCAGGGTAAGCGAATCGTCTTCTCTGGCGATACGTCCTGGTTTCCTCCGCTTGCAACG
+TTTGCCCAGGGGGCGGATATCCTGGTACATGAGGCGGTACATGTCCCTTCGGTAGCAAAA
+CTGGCTAATAGTATTGGCAACGGAAAAACGCTGGCTGAAGCGATTGCGTCGCATCACACC
+ACGATTGAAGATGTCGGTAAGATTGCTCGCGAGGCCCACGTGAAAAAACTGGTGTTAAGT
+CATCTGGTGCCTGCGACGGTTGCGGATGACGTCTGGCAACAGGAAGCCATGAAAAATTAC
+CCGGGCCCTGTCATTGTCGGTCATGACAATATGACGATAAGCGTACCGTAAATGTCGCAA
+CGCACAGAGAAAAAAATCGGGAAACGTTCGCAGGCCACCGGTGCAAAACGGCAGCTTATC
+TTAACCGCCGCGCTTGCCGTTTTTTCCCAGTATGGCATTCATGGCGCGCGTCTTGAACAG
+GTCGCCGAGCGGGCAGGCGTCTCCAAAACCAATCTGCTTTATTATTATCCCTCGAAAGAG
+GCGCTGTATGTCGCGGTAATGCGACAGATTCTGGATGTCTGGTTGGCGCCGCTCAAGGCG
+TTTCGCGCAGAATTTTCCCCTCTGGAGGCCATCAAAGAGTATATCCGTCTCAAGCTGGAG
+GTTTCGCGTGATTATCCGCAGGCGTCGCGGCTCTTCTGCATGGAGATGCTGGCGGGCGCG
+CCGCTCTTAATGGATGAACTGACCGGCGATCTAAAAGCGTTGATAGATGAAAAATCCGCG
+CTGATTGCCGGATGGGTGCACAGCGGGAAACTCGCGCCCGTTTCTCCGCATCATTTGATC
+TTCATGATTTGGGCCGCCACGCAACATTACGCCGATTTCGCCCCTCAGGTTGAAGCGGTA
+ACCGGCGCGACGCTTCGCGATGAAGCCTTTTTCAACCAAACGGTCGAAAGCGTTCAGCGC
+ATTATTATTGAAGGGATTCGCGTGCGTTAAATGGCGAAACAACAACGGATGGGCTGGTGG
+TTTCTTTGCCTTGCATGTGTCGTGGTAATGGTTTGTACCGCGCAACGCATGGCGGGCCTG
+CACGCCTTGCAGATGCAGGCGACGGCCTCTGCTGCGGTGGTCAGCGCTCCCTCCTCGACA
+GATGACGGCTCGCCGGTCACTCCCTGCGAATTAAGCGCCAAGTCGCTGCTGGCGGCGCCT
+CCAGTACTCTTTGAAGGTGCTATCCTTGCGCTTTATCTACTGCTTTCCTTACTGGCGCCT
+GTCCGGGTCATGCGCCTGCCGTTTTCGCCTCCACGGGCTATTTCGCCGCCCACATTACGG
+GTACATCTACGATTTTGTGTCTTCCGTGAATGAATGATGATTTTATTCAGGCGGATACTG
+TTCTGCCTGTTATGGCTTTGGCTGCCCGTCTCCTGGGCGGCGGAAAGCGGCTGGCTGCGT
+TCGCCCGATAACGACCATGCCAGCATACGGCTACGTGCCGATACGTCCGCTAACAGTGAG
+ACCCGGCTGTTGCTGGATGTCAAACTGGAAAACGGCTGGAAAACCTACTGGCGCGCGCCG
+GGGGAAGGGGGCGTGGCACCCTCTATCGCCTGGAAAGGCGACATGCCTGAGGTAAGCTGG
+TTCTGGCCAACCCCCTCGCGCTTTGATGTGGCGAATATCACCACCCAGGGATATCACGAC
+GAGGTGACCTTTCCGATGATCGTGCGCGGTACGCCGCCGGCGACCTTGCGCGGTGTGTTG
+ACGTTATCAACCTGCAGCAATGTTTGTCTGTTGACCGATTACCCCTTTTCCGTGACGCCC
+ACTGTGCAGAATGCCGATTTTGCCCATGACTATGCGCGGGCGATGGGTAAAGTTCCGCTC
+CGCAGTGGGCTAACGGACTCGCTTGACGTTGGCTATCGCCCGGGAGAACTGGTGGTCACT
+GCTACGCGAGCGGCGGGCTGGTCATCGCCCGGGCTCTATCTTGACACCATAGATGACGTC
+GATTTTGCGAAGCCTCGCCTGCGCGTAGAGGGCGACAGGTTACAGGCGACGGTGCCGGTG
+ACGGACAGTTGGGGCGAAAAGGCGCCCGATTTGCGCGACAAATCGCTGACCCTCGTGTTA
+GCCGATGGCGCTATCGCCCAGGAGAGCACGCAAACCATTGGCGCTGCGCCAGCGCAAACG
+CCGGACAATGCGGCGCTACCTTTCTGGCAAGTTGTAATGATGGCGCTAATCGGCGGACTG
+ATTCTTAATTTAATGCCCTGCGTACTGCCTGTTCTGGGCATGAAACTTGGCTCTATTTTA
+TTGGTAGAGGAAAAAAGCCGCTCTCACATCAGGCGACAATTTTTGGCTTCGGTCGCCGGT
+ATCATTGCGTCATTTATGGCGCTGGCGGCGTTTATGACCCTCCTTCGCCTGTCAAACCAT
+GCGCTGGCCTGGGGAGTCCAGTTCCAGAATGCATGGTTTATTGGTTTTATGGCGCTGGTG
+ATGTTGTTGTTTAGCGCCAGCCTGTTCGGGCTTTTTGAGTTCAGGCTTCCCTCATCTATG
+ACCACGAAACTGGCCACTTACGGCGGTAACGGTATGTCGGGACATTTCTGGCAGGGGGCG
+TTCGCCACGCTGCTGGCGACGCCTTGTAGCGCGCCGTTTCTGGGCACGGCGGTCGCGGTG
+GCGCTCACGGCGTCGCTGCCGACGCTGTGGGGGCTGTTCCTTGCGCTTGGCCTGGGAATG
+AGCGCGCCGTGGCTACTGGTCGCGATACGACCAGGGCTTGCGCTACGTTTACCGCGCCCC
+GGGCGTTGGATGAATGTCCTGCGCAGGATCCTCGGTCTGATGATGCTGGGGTCGGCTATC
+TGGCTGGCGACGTTACTCCTGCCGCATTTCGGCTTCACTGCGTCAAAGAGCGCGCAAGAC
+ACGGTTCAGTGGCAACCGTTGAGTGAACAGGCAATCCAGTCGGCGCTGGCGCAGCATAAG
+CGGGTATTTGTCGATGTCACTGCGGACTGGTGTATTACCTGTAAAGTGAATAAATACAAC
+GTCCTGCAAAAAGAGGATGTGCAGGCCGCCTTGCAACAGCCGGATGTTGTGGCGCTGCGG
+GGAGACTGGACGCTGCCGTCCGATGCCATTACAGATTTTCTGAAAACGCGCGGCCAGGTC
+GCCGTGCCGTTTAATCAGGTATATGGCCCCGGTTTGCCGGAAGGGGAGGCACTGCCCACT
+TTGCTGACCCGCGATGCGGTATTACAAACGTTGAAAAAAGCGAAAGGAATAACCCAATGA
+ATGAAATACATGATTGTTTTACTGCTGGCGCTGTTTTCGACGCTGAGCATCGCGCAAGAA
+ACCGCTCCTTTTACGCCGGATCAGGAAAAGCAGATTAAAAATCTGATCCATGCGGCGTTG
+TTTAACGATCCTGCCAGCCCGCGGATAGGCGCTAAACACCCTAAGCTGACGCTGGTGAAC
+TTTACGGATTACAACTGCCCGTACTGCAAACAGCTCGATCCGATGCTGGAAAAGATTGTG
+CAGAAATATCCTGACGTTGCGGTCATTATTAAACCGCTGCCATTCAAAGGAGAGAGTTCC
+ATACTGGCGGCGCGTATTGCGCTGACCACCTGGCGCGATCATCCGCAACAGTTCCTCGCG
+CTACATGAAAAACTTATGCAAAAGCGCGGTTACCATACGGATGACAGTATTAAACAGGCC
+CAGCAGAAAGCAGGGGCGACGCCAGTGACGCTGGATGAAAAAAGCATGGAAACGATACGC
+ACTAATTTGCAGTTGGCAAGACTGGTCGACGTGCAAGGAACGCCAGCGACGATCATTGGC
+GACGAGCTGATTCCGGGCGCAGTGCCCTGGGATACGCTGGAAGCGGTGGTGAAAGAAAAA
+CTGGCGGCTGCCAATGGCGGGTAAATGATTACACATTCTTTCGGCATCGTTAATTATTTT
+GTATTATTTGGCTACCTCCTGGCCATGATGTTAGTCGGTGTCTATTTTTCCAGACGGCAA
+AAAACAGCAGACGATTATTTTCGCGGTGGTGGCCGGGTTCCTGGTTGGGCGGCTGGGGTC
+AGTGTATTTGCTACTACGTTAAGCTCAATTACATTTATGTCAATTCCTGCCAAAGCGTTT
+ACTTCCGACTGGACGTTTATCATTGGTCAGTATCTGGCTATCGCAATTTTACCGCTGGTT
+TTTTATTTCTATATTCCGTTTTTTCGGAAATTGAAAGTCACATCAGCCTATGAATATCTC
+GAAGCACGGTTCGATGTGCGCTGCCGTCTGTTCGCCAGCATGTCATTTATGTTGTTTCAT
+ATTGGACGTATCGCCATTATCACTTTCCTCACCGTGCTGGCCTTGCGCCCCTTCATCGCT
+ATAGACCCGGTGATTTTGGTACTGTTGATTAGTGTGATGTGTATCATTTATACCTGGATG
+GGGGGGAATATGGAAAGTCTATTAAATCGTTTATATGACGCGTTAGGCCTGGATGCGCCA
+GAAGATGAGCCACTGCTTATCATTGATGATGGGATACAGGTTTATTTTAATGAATCCGAT
+CATACACTGGAAATGTGCTGTCCCTTTATGCCACTGCCTGACGACACTCTGACTTTGCAG
+CATTTTTTACGTCTTAACTACGCCAGCGCCGTCACTATCGGCGCTGATGCAGACAATACT
+GCTTTAGTGGCGCTTTATCGCTTGCCGCAAACCAGTACCGAAGAAGAGGCGCTCACTGGT
+TTTGAATTATTCATTTCAAACGTGAAGCAATTGAAAGAGCATTATGCAATGAAATACGAC
+CTTATTATTATCGGCAGCGGTTCGGTTGGCGCCGCCGCTGGTTATTACGCCACCCGCGCC
+GGGCTAAAGGTCCTGATGACCGATGCGCATATGCCGCCTTATCAACAGGGCAGCCACCAC
+GGCGATACCCGTCTTATCCGCCACGCTTATGGTGAAGGCGAAAAATATGTCCCGCTGGTG
+CTTCGCGCCCAGACGCTTTGGGATGAGCTCTCCACACACAATGAAGAGCCTATTTTTGTC
+CGCTCCGGCGTCGTCAACCTCGGCCCGGCCGATTCCGCTTTCTTAGCCAACGTCGCACGA
+AGCGCGCAACAGTGGCAATTGAACGTCGAGCGCCTGGACGCGACGGCCCTCATGACGCGC
+TGGCCGGAAATTCGCGTGCCCGATAATTATATCGGGCTGTTTGAAGCTGACTCCGGTTTC
+CTGCGCAGCGAATTAGCCATTACCACATGGCTTCGTCTGGCCCGAGAGGCAGGCTGCGCA
+CAGCTATTCAACAGCCCGGTAAGCCATATTCACCATGATGATAACGGTGTGACGATAGAG
+ACGAGTGAAGGCTGCTACCACGCCAGCAAAGCGCTGATTAGCGCGGGCACCTGGGTCAAA
+ACGCTGGTACCGGAGCTGCCCGTTCAGCCCGTACGTAAAGTTTTTGCCTGGTTTAAGGCG
+GATGGACGTTACAGCACTAAAAACCGCTTTCCGGCCTTTACCGGCGAAATGCCCAACGGC
+GATCACTATTACGGTTTCCCGGCGGAGAACGACGAGTTAAAAATCGGCAAACACAATGGC
+GGGCAGCGAATACAGGCACCGGAAGAGCGCAAGCCCTTTGCCGCCGTTGCCAGCGATGGC
+GCGGAAGCATTTCCTTTCCTGCGTAACGTACTGCCGGGTATCGGCGGTTGTTTACATGGG
+GCGGCATGTACCTATGATAATTCGCCGGACGAGGATTTTATTATCGATACGCTGCCTGGC
+CATGAGAATACGCTTGTCATCACTGGACTCAGCGGACATGGTTTTAAATTCGCCCCGGTG
+TTAGGAGAAATCGCTGCGGATTTTGCGTTGGGAAAAACGCCCTCCTTTGATCTGACGCCG
+TTCCGGCTTTCCCGTTTTAGCCAATAAATGCAAATACAGAGCTTCTATCACTCAGCTTCA
+CTAAAAACCCAGGAGGCTTTTAAAAGCCTACAAAAAACCTTATACAACGGAATGCAGATT
+CTCTCAGGCCAGGGCAAAGCGCCGGCTAAAGCGCCCGACGCTCGCCCGGAAATTATTGTC
+CTGCGAGAACCTGGCGCGACATGGGGGAATTATCTACAGCATCAGAAGACGTCTAACCAC
+TCGCTGCATAACCTCTATAACTTACAGCGCGATCTTCTTACCGTCGCGGCAACCGTTCTG
+GGTAAACAAGACCCGGTTCTAACGTCAATGGCAAACCAAATGGAGTTAGCCAAAGTTAAA
+GCGGACCGGCCAGCAACAAAACAAGAAGAAGCTGCGGCAAAAGCATTGAAGAAAAATCTT
+ATCGAACTTATTGCAGCACGCACTCAGCAGCAAAATGGCTTACCTGCAAAAGAAGCTCAT
+CGCTTTGCGGCAGTAGCGTTTAGAGATGCTCAGGTCAAGCAGCTCAATAACCAGCCCTGG
+CAAACCATAAAAAATACACTCACGCATAACGGGCATCACTATACCAACACGCAGCTCCCT
+GCCGCAGAGATGAAAATCGGCGCAAAAGATATCTTTCCCAGTGCTTATGAGGGAAAGGGC
+GTATGCAGTTGGGATACCAAGAATATTCATCACGCCAATAATTTGTGGATGTCCACGGTG
+AGTGTGCATGAGGACGGTAAAGATAAAACGCTTTTTTGCGGGATACGTCATGGTGTGCTT
+TCCCCCTATCATGAAAAAGATCCGCTTCTGCGTCAGGCCGGCGCTGAAAACAAAGCCAAA
+GAAGTATTAGCTGCGGCACTTTTTAGTAAACCTGAGTTGCTTAACAGAGCCTTAGAGGGC
+GAAGCGGTAAGCCTGAAACTGGTATCCGTCGGGTTACTCACCGCGTCGAATATTTTCGGC
+AAAGAGGGAACTATGGTCGAGGATCAAATGCGCGCATGGCAATCGTTGACCCAGCCGGGA
+AAAATGATTCATTTAAAAATCCGCAATAAAGATGGCGATCTACAGACGGTAAAAATAAAA
+CCGGACGTCGCCGCATTTAATGTGGGTGTTAATGAGCTGGCGCTCAAGCTCGGCTTTGGC
+CTTAAAGCATCAGATAGCTATAATGCCGAAGCGCTACATCAGTTATTAGGCAATGATTTA
+CGCCCTGAAGCCAGACCAGGTGGCTGGGTTGGCGAATGGCTGGCGCAATACCCGGATAAT
+TATGAGGTCGTCAATACATTAGCGCGCCAGATTAAGGATATCTGGAAAAATAACCAACAT
+CATAAAGATGGCGGCGAACCCTATAAACTCGCACAACGCCTTGCCATGTTAGCCCATGAA
+ATTGACGCGGTGCCCGCCTGGAATTGTAAAAGCGGCAAAGATCGTACAGGGATGATGGAT
+TCAGAAATCAAGCGAGAGCTCATTTCTTTCCATCAGACCCATATGTTAAGTGCGCCTGGT
+AGTCTTCCGGATAGCGGTGGACAGAAAATTTTCCAAAAAGTATTACTGAATAGCGGTAAC
+CTGGAGATTCAGAAACAAAATACGGGCGGGGCGGGAAACAAAGTAATGAAAAATTTATCG
+CCAGAGGTGCTCAATCTTTCCTATCAAAAACGAGTTGGGGATGAAAATATTTGGCAGTCA
+GTAAAAGGTATTTCTTCATTAATCACATCTATGAAACGATATATACTGGCTACCGCGATA
+GCGTCTCTTGTTGCAGCCCCGGCAATGGCGCTGGCCGCTGGCAGCAATATTCTCAGCGTA
+CATATTCTCGATCAGCAAACAGGCAAACCAGCGCCCGGCGTGGAGGTGGTACTGGAGCAG
+AAAAAGGATAACGGATGGACGCAATTAAACACCGGGCATACCGACCAGGATGGACGAATT
+AAAGCACTGTGGCCCGAAAAAGCTGCCGCGCCGGGGGATTATCGCGTTATTTTTAAAACC
+GGCCAGTATTTTGAAAGTAAAAAACTGGACACGTTTTTCCCGGAGATTCCCGTCGAGTTT
+CATATCAGCAAAACGAATGAGCACTATCATGTGCCGCTGTTATTAAGTCAGTATGGTTAT
+TCAACCTATCGCGGGAGCTAAATGGCAAAGATTCTGGTGCTCTATTATTCCATGTACGGA
+CACATTGAAACCATGGCGCACGCGGTGGCGGAAGGGGCAAAGAAAGTCGACGGCGCAGAG
+GTCATTATAAAGCGTGTGCCAGAAACAATGCCGCCTGAAATCTTCGCAAAAGCTGGCGGT
+AAAACGCAAAACGCACCGGTTGCCACCCCACAGGAGCTGGCGGATTACGATGCCATTATT
+TTTGGTACGCCAACCCGGTTTGGCAATATGTCAGGCCAGATGCGTACCTTCCTGGACCAA
+ACCGGCGGACTGTGGGCATCCGGCGCGCTATACGGCAAGCTCGGCGGCGTGTTCAGTTCT
+ACCGGAACGGGCGGCGGCCAGGAGCAGACCATCACCTCGACCTGGACTACGCTTGCCCAT
+CATGGGATGGTGATTGTCCCGATAGGCTATTCCGCACAGGAACTGTTTGACGTCTCCCAG
+GTTCGCGGCGGTACGCCTTACGGCGCAACGACTATCGCTGGAGGCGACGGTTCACGTCAA
+CCAAGCCAGGAGGAACTCTCTATCGCTCGCTATCAGGGGGAATACGTCGCCGGTCTGGCA
+GTCAAACTCAACGGCTAAATGGAGCCTCAACCCCCACGTCTTAAACCCGGAAAAATCCTT
+GACACTCTGGGTGCTATGCAAAAAAGCCTGACACGTGCCTCCCAGCGTATTGCGCAATAT
+ATTTTAGCCTTCCCCAGACAGGTGACACAGTCATCTATTGCCGATTTGTCGCGCGACACA
+CAGGCCGGAGAAGCCACGGTTATTCGCTTTTGTCGCACCCTGGGCTATAAAGGTTTTCAG
+GATTTTAAAATGGACCTGGCCATTGAACTTGCCACTACCGAGTCTGATGACAGTAGTCCT
+CTACTGGATGCCGAAGTTAGCGAATCCGACGATGCCCACGCCATTGGTTTAAAATTGCAG
+AACACCATTAGTAATGTATTATCTGAAACGCTAAATCTGCTTGATATGCAACAGGTTCTC
+GGTGTCGTGGACGCCCTACGTCACTGTCACTCAGTTTATATCTTTGGTGTGGGCTCATCG
+GGGATCACGGCGCTGGATATGAAACACAAGCTAATGCGTATTGGTTTACGGGGCGATGCG
+GTAAGCAATAACCATTTTATGTACATGCAGGCTACGCTATTAAAAGCAGGCGATGTCGCG
+ATGGGTGTCAGTCACTCGGGCACATCGCCAGAAACAGTGCATTCACTCCGATTGGCCCGA
+CAGGCTGGCGCCACCACAGTCGCCATTACCCATAATCTGGGTTCTCCATTATGTGAAGAG
+GCCGATTTTTGCCTGATCAATGGTAATCGGCAAGGAATGTTGCAGGGTGACTCGATCGGT
+ACGAAAGCCGCGCAGCTTTTCGTCTTTGACCTGCTCTATACCCTTCTTGTACAGTCCTCG
+CCGGAACAGGCCCGAGAAAGCAAATTACGGACAATGAATGCCCTGGACATGACAAAAATG
+AAGAAACTGCCCGGCTTTACGCAAGATTACTTACTCAGCAAGGCGACGACCCTGCCTGAT
+AAAACACGCCTGGAGCGTGCCGTTGAACCGCTATGCGCGCGCCATCCCGGAGAGTGCGGC
+ATTCTTGCGCTGGATAACAGTCTGGACGCTTTTGCCGCCCGCTACCGCCTGACCGAAATG
+GCGGCGCGGACGCTGGATGTGCAGTATTATATTTGGGAAGACGATATGTCCGGGCGGCTG
+CTCTTTTCGGTTCTGCTGTCGGCGGCGAAGCGCGGCGTTCATGTTCGTCTGCTGCTGGAT
+GATAACAATACGCCTGGTCTGGATGATACGTTGCGCTTGCTGGATAGCCATCCTAATATC
+GAAGTTCGTCTGTTTAATCCTTTCTCTTTTCGTACGCTACGCGCGCTGGGATATTTGACG
+GATTTTGCGCGGCTGAATCGGCGGATGCACAATAAAAGTTACACTGCCGACGGCGTAGTG
+ACGCTGGTCGGTGGGCGCAACATCGGCGATGCCTATTTCGGCGCTGGCGAGGAGCCGCTA
+TTTTCCGATCTGGACGTGATGGCCATTGGCCCGGTGGTCAATGATGTCGCCAATGATTTT
+GAACGTTACTGGCGCTGTAGTTCAGTGTCGACATTGCAGCAAGTATTATCCCTTTCTGAG
+CAGGAACTGACGCAGCGTATCGAACTTCCCGAATCCTGGTATAACGATGAGATCACCCGC
+CGTTATCTGCATAAGCTGGAAACCAGCCAGTTTATGGCGGATCTCGATCGCGGAACGTTG
+CCGCTGATTTGGGCAAAAACACGCTTGCTTAGCGATGACCCTTCTAAAGGCGAGGGGAAG
+GCGCAGCGCCATTCGCTTCTTCCGCAGCGATTATTTGACGTGATGGGGTCGCCGACGGAG
+CGTATCGACATTATTTCCGCTTACTTTGTCCCTACGCGCGCAGGCGTGGCGCAGTTGCTT
+AATCTGGTCAGGAAAGGTGTGAAGATCGCCATCTTAACTAACTCTCTGGCGGCCAACGAT
+GTGGCGGTCGTTCACGCAGGGTACGCGCGCTGGCGCAAGAAATTACTGCGCTATGGCGTG
+GAGCTCTACGAACTGAAACCGACCCGCGAACATGAAACCGCCGTACATGATCGCGGACTC
+ACCGGGAACTCAGGTTCCAGCTTACATGCTAAAACGTTCAGTATTGATGGTAGTAAGGTG
+TTTATCGGGTCGCTTAATTTTGATCCCCGTTCAACGCTTTTAAATACCGAAATGGGCTTT
+GTCATTGAAAGTGAAACGCTGGCGACGCTTATTCATAAGCGTTTTACGCAGAGCCAACGC
+GATGCGGCCTGGCAACTGCGGCTGGATCGCTGGGGACGAATTAACTGGATCGATCGTCAG
+CAAGAAGAGGAAAAGGTGTTAAAGAAAGAACCCGCTACGCGTTTCTGGCAGCGAGTTCTG
+GTACGGTTGGCGGCAATTTTACCTGTGGAATGGTTGCTGTGAATGCCAACTCAAGAAGCA
+AAAGCGCACCGCGTCGGCGAATGGGCAAGCCTGCGTAATACGTCGCCGGAAATTGCCGAA
+GCCATTTTTGAAGTCGCTCACTATGACGAGAAACTGGCAGAAAAAATATGGGAAGAAGGT
+AGCGATGAGGTGCTGATCAAAGCCTTTGAGAAAACGGACAAAGACTCGCTCTTCTGGGGC
+GAACAAGTCATCGAACGTAAGAACGTATAAATGTATCCCGTTGACCTGCATATGCATACC
+GTCGCCAGCACTCATGCCTACAGTACTCTGAGCGATTATATCGCGGAAGCCAAACGCAAA
+GGCATTAAACTTTTTGCGATTACCGATCATGGTCCGGACATGGAAGATGCGCCGCATCAC
+TGGCATTTTATTAACATGCGCATCTGGCCGCGTCTGGTTGACGGCGTGGGGATACTGCGT
+GGCATTGAGGCGAATATCAAGAATATTAACGGTGAAATTGATTGTTCCGGAAAGATGTTC
+GACTCGCTGGATCTGATTATCGCAGGCTTTCATGAGCCCGTTTTTGCGCCGCATGATAAA
+GAAACCAATACTCAGGCGATGATCGCGACCATCGCCAGCGGCAAGGTGCATATAATTAGT
+CACCCCGGAAATCCAAAGTATCCAGTGGAGGTTAAAGCCATCGCGCAGGCGGCGGCGAAA
+CACCATGTAGCGCTGGAAATCAACAACTCTTCTTTTCTGCATTCGCGTAAAGGAAGCGAA
+GATAATTGCCGCGCGGTCGCTGCCGCCGTACGCGATGCGGGAGGCTGGGTAGCGTTAGGC
+TCTGATTCCCATACGGCCTTTACGCTTGGCGATTTCACCGAATGCCGGAAAATTCTGGAT
+GCGGTGAATTTTCCGGAAGATCGAATCCTGAACGTCTCTCCGCAGCGCTTACTGGCCTTT
+CTCGAATCACGCGGTATGGCGCCTGTACCGGAATTTGCCGAACTTATGAATGAGTTTTCA
+ATCCTGTGCCGTGTGCTGGGATCGTTGTTTTACCGCCAACCGCAAGATCCTTTACTGGTT
+CCGCTGTTTACGTTAATCCGTGAAGGTAAACTGGCGGCAAACTGGCCGCTGGAGCAGGAT
+GACATGCTGGCGCGTTTACAGAAAAGCTGCGATATCACGCAGATTTCCACTGATTACAAT
+GCGTTATTTGTTGGGGAAGAGTGCGCGGTAGCGCCATACCGCAGTGCGTGGGTCGAAGGC
+GCGGAAGAGTCTGAGGTGCGCGCTTTTTTAACGTCGCGAGGGATGCCGCTGGCCGATACG
+CCTGCCGATCACATTGGCACTTTATTGCTCGCGGCCTCCTGGCTGGAAGATCAGTCTGCC
+GAAGATGAAAGTGAAGCGCTGGAAACCTTATTTGCCGATTATCTGCTTCCCTGGTGCAAT
+ACCTTCCTCGGTAAAGTTGAAGCCCATGCCGTTACGCCATTCTGGCGCACTCTGGCGCCG
+CTAACGCGTGATGCGATAGGGGCCATGTGGGATGAACTTCAGGAAGAAGATGAAGAAATG
+ATGCGCGCCATGAACATACTTCTTTCTATTGCTATCACTACGGGCATCCTTTCTGGAATA
+TGGGGATGGGTGGCCGTCTCCCTGGGGTTACTAAGCTGGGCCGGTTTTTTAGGCTGTACG
+GCTTATTTCGCCTGTCCGCAGGGCGGCTTTAAGGGATTGTTGATTTCCGCCTGTACGCTG
+TTAAGCGGTATGGTGTGGGCGCTGGTCATTATTCACGGTAGCGCGTTGGCGCCGCATCTG
+GAAATTGTCAGTTACGTGTTGACGGGGATCGTGGCATTCCTGATGTGTATCCAGGCAAAG
+CAGCTATTGCTTTCTTTTGTTCCGGGAACATTTATCGGCGCCTGCGCGACATTTGCAGGG
+CAGGGTGACTGGCGGTTGGTATTACCGTCGCTGGCGCTGGGGCTAATCTTTGGCTATGCC
+ATGAAAAATAGTGGGCTATGGCTGGCATCACGCCGCGAGCAACATTCAGCGAATACGGCG
+GTCACAAAAATGAAAAAAAACCTGCTGGGATTCACCCTCGCATCCTTGTTATTCACGACC
+GGTTCCGCCGTGGCGGCGGAGTATAAAATTGATAAAGAAGGCCAACATGCGTTCGTCAAT
+TTCCGCATCCAGCATCTGGGCTACAGCTGGCTATACGGCACCTTTAAAGATTTCGACGGC
+ACGTTCACTTTTGACGAAAAAAATCCGTCAGCAGACAAAGTGAATGTGACCATTAACACC
+AATAGCGTCGACACTAACCATGCCGAACGTGACAAACACCTGCGTAGCGCGGAGTTTCTT
+AATGTTGCGAAATTCCCGCAGGCAACCTTCACCTCTACCAGCGTGAAAAAAGAGGGCGAT
+GAACTGGATATTACCGGCAATCTGACGCTCAATGGCGTGACTAAACCGGTGACGCTGGAA
+GCGAAGCTGATGGGCCAGGGCGACGATCCGTGGGGCGGTAAGCGCGCGGGCTTTGAGGCC
+GAAGGAAAAATTAAGCTGAAAGATTTCAATATAACTACCGATCTCGGCCCAGCCTCACAA
+GAGGTGGAGCTTATCATCTCAGTAGAAGGCGTTCAGCAGAAGTAAATGTTACTGATGATG
+GCGCTGATCGTGCGTATTATCTGGCGGCTTTATTCTCCGCCGCCCGTTGCGTTGACCAGC
+TATTCCCGTTTAACGCGCATTGGCGCCGCCGCGGGTCATATCCTTCTGTATCTCCTGCTC
+TTTGCGATAATCATTAGCGGCTACCTGATTTCCACCGCCGACGGTAAACCGATTAGCGTC
+TTTGGCTGGTTTGAGATTCCGGCCACGCTTACGGACGCGGGCGCGCAGGCTGACATCGCC
+GGAACACTGCATCTGTGGTTTGCCTGGTCGCTGGTCATTATCTCGCTCTCGCATGGGGTT
+ATGGCGCTAAAACACCATTTCATCGATAAAGACGACACACTGAAACGTATGACAGGAATG
+TCGTCATCTGACTATGGAGCTCAAAAATGAATGGTTAAGTTATCAATGACGCTGCGCCTG
+ACAATTTCTTTTATCGCCATACTTATCCTCGCCTGTACCGGCATTAGCTGGACGCTCTAT
+AACGCGCTGAGCAAAGAATTAACGTATCGGGATGATATGACGCTAATAAATCGGGCGGCG
+CAAATGCAGCAACTGTTACTGGATGGCGCCAGGCCGGAAAATCTGCCGCTCTATTTCAAT
+CGGATGGTGGATACGAAGCAGGATATCTTATTGATCCACTCAGCAACAGGCCATAATGTT
+GCGATTAATCATAGCGGCATCCCCGACCAACGCTTTAACGAGATTCCGCTGGCTAAAAAC
+ATCACCCGCGAAACCTTATTTCGCCAGGCGGTACAAGGCACGGAGCTGACCGCGGTACGA
+GTAAACGCCAGAAGCGGCGATAACCCGCTGACCCTTACTATTGCCAGGCTGGCGACGGAA
+AGGCGGCAAATGCTGGCGCAATATCGCCGCAACAGTTTGCTGATTAGCCTTATCGCGATC
+CTCGTCTGTTCGGCGCTCAGTCCATTAGTCATCAGAAACGGGCTGCGGGCCATTACGTCG
+CTCAGCCGACTCACCGCGGCGACAGATAGCGGCACACTTCGCCAGCCGCTGGCGGAACAG
+GCGTTACCCGTCGAGCTCAGGCCGCTTGGGCAAGCGCTAAATACCATGCGCCAGAAGCTT
+TCCGACGATTTTGAACGCCTGAACCAATTTGCCGACGATCTGGCGCATGAGCTGCGCACG
+CCGGTTAATATTTTACTGGGGAAGAATCAGGTTATGCTGAGTCAGGAACGCAGCGCCGAA
+GAGTATCAACAAGCCCTTGTCGATAATATTGAAGAGCTGGAGGGACTGTCGCGACTGACA
+GAAAATATTCTCTTTCTGGCACGCGCGGAGCACCAGAATATAGCGGTAAAAAAACAGCCT
+GTTTCGCTCAATGCGCTGGTCGAAAATATGCTGGATTATCTTAGCCCCCTTGCCGAAGAG
+AAGCACATCTGTTTTATAAATCAATGTCAGGGAACGGTATGGGCTGACGAAATATTATTA
+CAAAGAGTGCTCTCAAACCTGCTGACGAATGCCATCCGTTATTCTGATGAAAACGCCGTG
+ATACGTATTGAAAGCGCTTATGATGATAACGTTGCAGAAATTCGGGTCGCTAATCCGGGC
+AGCCCCACCGCCGATGCGGATAAGCTTTTCCGGCGTTTTTGGCGAGGAGATAATGCCCGC
+TACACTGCCGGTTTCGGCCTGGGGTTATCGTTAGTTAACGCGATTGCCCTATTGCACGGT
+GGCTCGGCATCTTACCGCTATGCCGATGAACATAATATCTTTTCGGTTCGTCTGCCTGAT
+AGCGGTGATAGCTAAGTGATATGTCTCAAAGTCCAGGGCGGCATTGGTGAAATTTTTACG
+GTGACGCAGCAGGCGGATAAATTCTTTCCGGCTACGCAGTTCCACTGGAGCTGGACGGAA
+AGCACAGTACCTGTATTGATGATTGGTTTTCTGTTTGCCAATATTCAGCAATTTACTGCC
+AGTCAGGATGTGGTCCAACGCTATATCGTGACTGACTCCATAGAGGAAACGAAGAAAACA
+TTACTTACAAATGCCAAACTGGTTGCTGTGATCCCTGTTTTCTTTTTTGCTATCGGCTCG
+GCATTATTTGTCTACTATCAGCAACATCCACAATTATTACCGGCGGGATTCAACACTGGC
+GGCATTTTGCCCTTATTCGTGGTCACCGAAATGCCAGTCGGCATTGCAGGGTTGATAATC
+TCCGCTATTTTCGCTGCCGCGCAGTCCAGCATCTCCAGCAGCTTAAACAGCATTTCCAGT
+TGTTTTAATTCCGATATCTATCAGCGTTTGAGTCATAAAAAAGGAACGCCAGAAAACCGT
+ATGAAAATAGCTAAGTTAGTTATTCTGGTCGCGGGCCTGATAAGTAGCGCGGCCTCGGTA
+TGGCTGGTCATGGCCGATGAATCAGAAATCTGGGATGCATTTAATAGTCTGATAGGTCTG
+ATGGGAGGGCCAATGACCGGTCTGTTCATGCTGGGCATTTTCTTTAAACGAGCAAATGCC
+GGGAGTGCGGTTTTAGGAATTATTATCAGCGTCATTACCGTGCTGGGCACACGCTATGCC
+ACTGACCTTAACTTCTTCTTTTATGGGGTCATTGGCTCGCTAAGCGTGGTGATCAGCGGC
+GTTATTTTCGCCCCGTTATTTGCCCCGGCACCGCCATTGACGCTGGATGAAAAACCTGAA
+CCAAAGGTGACATTAATGAAAATCAACAGATATCTTCTGGGTATGGTTTCGTTTATAGCA
+TTTTCATCATATCTACAAGCGGCAACCCTTGATTATCGGCATGAATATGCTGATAGAACC
+AGAATTAATAAAGACCGTATTGCTATAATTGAAAAGCTTCCTAACGGCATTGGTTTTTAT
+GTCGATGCCAGCGTTAAATCGGGAGGAGTAGATGGTGAGCAGGATAAGCATTTAAGCGAT
+CTCGTCGCAAACGCTATAGAACTGGGCGTAAGTTATAATTATAAAGTTACGGACCATTTT
+GTTTTGCAGCCTGGATTTATATTTGAAAGCGGTCCAGACACTTCAATTTATAAGCCTTAT
+TTAAGGGCGCAATATAATTTTGATTCTGGTGTTTATATGGCTGGTCGTTACCGTTATGAC
+TATGCAAGGAAGACAGCTAACTATAATGATGATGAGAAAACGAATAGATTTGATACTTAT
+ATAGGTTATGTTTTTGATGAGTTGAAATTGGAATATAAATTTACCTGGATGGATAGCGAT
+CAAATTAAATTTGATAACAAAAAAACAAACTATGAACATAATGTGGCTTTAGCCTGGAAA
+CTGAATAAGTCATTTACACCATACGTTGAGGTCGGAAATGTAGCGGTGAGAAATAATACC
+GATGAGAGACAGACCCGTTATCGCGTTGGATTACAATACCACTTTTGAATGACGAAATAC
+GGTGTTATAGGTACAGGTTATTTTGGCGCTGAACTGGCGCGATTTATGTCTAAGGTTGAA
+GGGGCGAAAATCACTGCGATTTACGATCCGGTAAATGCGGCTCCGATAGCGAAAGAGCTG
+AACTGTGTCGCCACTTCAACGATGGAGGCGCTTTGTACCCATCCTGATGTGGATTGCGTA
+ATTATTGCTTCACCAAATTACTTACATAAAGCGCCGGTCATTGCGGCGGCTAAAGCGGGT
+AAACACGTGTTTTGTGAAAAACCTATCGCCTTAAATTACCAGGATTGTAAGGATATGGTT
+GATGCCTGCAAAGAAGCTGGTGTTACCTTTATGGCGGGTCACGTTATGAACTTTTTTCAC
+GGGGTTCGCCACGCTAAAGCGCTCATCAAAGCCGGTGAAATCGGTGAAGTTACACAAGTT
+CACACTAAACGTAATGGTTTTGAAGACGTGCAGGATGAGATCTCATGGAAGAAGATTCGC
+GCAAAGTCAGGTGGGCATCTGTACCATCACATTCACGAGCTAGATTGTACACTGTTCATC
+ATGGATGAAACCCCATCCCTGGTTTCAATGGCGGCGGGGAATGTTGCGCACAAAGGTGAA
+AAATTTGGTGATGAAGATGATGTTGTCCTAATCACCCTTGAGTTTGAAAGCGGTCGTTTC
+GCGACACTTCAGTGGGGATCATCGTTCCACTACCCTGAGCACTATGTATTAATTGAGGGC
+ACGACAGGTGCAATTCTCATTGATATGCAAAACACGGCTGGTTATCTAATAAAAGCGGGC
+AAAAAAACACACTTTCTTGTGCATGAAAGCCAGGCGGAGGATGATGATCGTCGCAACGGT
+AACATATCCAGCGAGATGGATGGCGCAATCGCTTATGGTAAACCCGGTAAACGTACGCCG
+ATGTGGCTCTCATCAATTATGAAACTGGAGATGCAGTACTTGCATGATGTGATAAACGGT
+CTGGAGCCAGGCGAGGAGTTTGCTAAATTGCTAACGGGAGAAGCGGCGACAAATGCCATT
+GCTACCGCTGATGCTGCGACGCTTTCTTCAAACGAGGGGCGCAAAGTTAAACTCACTGAA
+ATTCTTGGCTAAATGACATCACGTCTTCAGGTCATACAGGGTGATATCACTCAACTTAGC
+GTCGATGCGATTGTGAATGCCGCTAACGCATCATTAATGGGCGGCGGTGGCGTAGACGGC
+GCAATTCATCGCGCGGCGGGGCCGGCATTGCTGGACGCCTGTAAACTCATCCGTCAGCAA
+CAGGGCGAATGTCAGACGGGACATGCGGTTATCACGCCTGCTGGCAAGCTTTCGGCAAAG
+GCGGTTATTCACACAGTGGGGCCCGTCTGGCGAGGCGGCGAACACCAGGAAGCTGAGCTA
+CTCGAAGAGGCATACCGGAATTGTTTGCTGCTTGCCGAGGCGAATCACTTTCGTTCCATC
+GCTTTTCCGGCAATCAGTACCGGCGTTTATGGCTATCCACGCGCCCAGGCCGCTGAAGTC
+GCCGTCAGGACGGTTTCAGATTTTATTACCCGTTACGCTCTGCCTGAACAGGTATACTTT
+GTCTGTTATGATGAAGAAACTGCCCGGCTTTACGCAAGATTACTTACTCAGCAAGGCGAC
+GACCCTGCCTGA
+>real_data_2
+ATGAAAAAATCATTACTCGCTGTTGCTGTGGCAGGGGCTGTTTTGTTGTCATCCGCCGTA
+CAGGCGCAGACAACGCCGGAAGGTTATCAATTACAACAGGTGCTGATGATGAGCCGCCAT
+AATCTGCGGGCGCCGCTGGCGAATAATGGCAACGTACTGGCGCAGTCGACGCCGAACGCC
+TGGCCGGCGTGGGACGTTCCCGGCGGGCAACTGACGACGAAAGGCGGCGTGCTGGAAGTC
+TATATGGGACACTACACACGTGAATGGCTGGTCGCGCAGGGGCTGATACCGTCGGGAGAA
+TGTCCGGCGCCCGACACGGTATATGCCTATGCGAATAGTTTGCAGCGCACCGTCGCCACC
+GCGCAATTTTTCATTACCAGCGCTTTCCCCGGCTGTGATATTCCTGTTCATCATCAGGAA
+AAAATGGGCACTATGGACCCTACCTTCAATCCGGTGATTACCGATGATTCCGCCGCGTTC
+CGGCAACAGGCCGTACAGGCGATGGAAAAGGCGCGTAGTCAGCTACATCTTGATGAGAGT
+TATAAACTGCTTGAGCAGATAACGCATTATCAGGACTCGCCGTCCTGCAAAGAGAAGCAT
+CAGTGTTCGCTAATCGACGCGAAAGATACCTTCAGCGCGAACTATCAGCAAGAGCCTGGC
+GTGCAGGGGCCGCTGAAAGTAGGGAACTCGCTGGTGGATGCGTTTACCCTGCAATATTAC
+GAAGGCTTTCCGATGGATCAGGTCGCTTGGGGCGGGATCCACACCGATCGGCAGTGGAAG
+GTGCTGTCAAAACTGAAAAACGGCTACCAGGACAGCCTGTTTACCTCACCCACGGTGGCG
+CGCAATGTCGCTGCGCCGCTGGTAAAATATATCGATAAGGTGCTGGTTGCCGAGCGCGTT
+AGCGCGCCGAAGGTTACCGTGCTGGTGGGGCATGATTCCAATATCGCGTCGCTGCTGACG
+GCGCTGGATTTTAAACCCTATCAGCTCCATGACCAGTATGAGAGAACGCCGATTGGTGGT
+CAGCTTGTCTTCCAACGCTGGCATGACGGTAACGCTAACCGGGATTTGATGAAAATCGAG
+TATGTCTACCAGAGCGCCCGGCAGTTACGTAATGCGGAAGCGTTAACGCTCAAATCGCCT
+GCGCAAAGGGTAACGCTGGAACTGAAAGGATGTCCGGTGGATGCGAACGGCTTCTGTCCG
+CTGGATAAGTTCGATAACGTCATGAACACTGCTGCAAAATAGATGGAAAAGAATAATGAA
+GTCATTCAGACCCATCCGCTTGTAGGATGGGACATCAGCACCGTCGATAGCTATGATGCG
+CTGATGCTGCGTTTACACTACCAGACCCCAAATCGTCCGGAACCGGAAGGGACTGAAGTT
+GGTCAAACGCTCTGGTTAACGACAGATGTAGCCAGGCAATTTATTTCAATATTAGAAGCC
+GGCATCGCCAAAATAGAATCAGGCGATTACCAGGAAAACGAGTATCGTCACCATTAGATG
+GAACTTAAGGATTATTACGCCATTATGGGCGTGAAACCGACGGACGATCTCAAGACGATT
+AAGACCGCCTATCGCCGACTGGCCCGCAAGTACCATCCAGATGTCAGCAAAGAACCCGAT
+GCCGAAGCCCGTTTCAAAGAGGTTGCTGAAGCATGGGAAGTGCTGAGTGATGAGCAACGG
+CGCGCCGAGTATGACCAGTTATGGCAACACCGTAACGATCCACAATTTAATCGCCAGTTC
+CAGCAACACGAAGGCCAGCCGTATAACGCCGAAGATTTTGATGATATTTTCTCGTCTATT
+TTTGGTCAGCACGGTCGTCATTCGCACCACCGCCACGCCGCACGCGGTCATGATATCGAA
+ATTGAAGTGGCGGTATTCCTGGAAGAAACGCTGGAAGAGCACCAGCGTACGATTAGCTAT
+TCCGTCCCCGTTTATAACGCGTTCGGCCTGGTGGAGCGGGAAATTCCCAAAACATTGAAT
+GTGAAAATCCCGGCTGGCGTCAGCAACGGGCAACGAATCAGACTGAAAGGCCAGGGCACG
+CCGGGGGAAAACGGCGGACCTAATGGCGATTTATGGCTCGTTATCCATATTGCCCCGCAT
+CCGCTCTTTGATATCGTCAATCAGGATCTGGAAGTCGTCCTTCCGCTTGCCCCATGGGAG
+GCGGCGCTCGGCGCTAAGGTGTCTGTGCCAACGCTTAAAGAGCGTATTTTGCTGACCATT
+CCCCCCGGCAGCCAGGCAGGTCAGCGGCTGCGTATCAAAGGAAAAGGATTAGCCAGTAAA
+AAGCACACTGGCGATCTCTATGCCATCATCAAAATCGTTATGCCGCCGAAACCTGACGAG
+AAAACAGCTGCCCTGTGGCAACAACTGGCGGACGCGCAGTCGTCCTTTGACCCACGCCAG
+CAATGGGGGAAAGCATAAATGGCTAACATCACTGTCACCTTTACCATCACCGAATTTTGT
+TTGCACACCGGCGTGACGGAAGAGGAGCTAAACGAAATCGTCGGACTTGGCGTAATTGAG
+CCTTACGAAGACGATAACGCCGACTGGCAATTCGACGATCGCGCAGCGAGCGTGGTACAA
+CGCGCGCTACGCTTACGCGAGGAGCTGGCGCTCGACTGGCCAGGGATCGCGGTCGCGTTA
+ACGCTGCTGGAAGAGAATTCACGGCTGCGCGAAGAAAACCGGTTACTGCTGCAACGCCTT
+TCTCGCTTTATCTCGCATCCCTAAATGTCATCTTGTTGGAGATTTACGGATTCGCTAACA
+AGCCTATGGCATACTGCGTTGATGAAGATTTTATTGATTGAAGATAACCAGAAAACCATT
+GAGTGGGTACGTCAGGGACTCACGGAGGCAGGCTATGTGGTTGATTATGCCTGTGATGGA
+CGAGACGGATTACACCTAGCCCTTCAGGAACATTATTCATTGATTATTCTTGATATTATG
+CTGCCGGGGCTTGATGGATGGCAGGTTTTACGCGCGTTGCGCACTGCATATCAGCCCCCT
+GTTATTTGCCTGACGGCGCGCGACTCGGTTGAGGATCGCGTCAAAGGTCTTGAGGCGGGC
+GCTAATGATTACCTTGTTAAGCCTTTTTCCTTCGCCGAACTGCTGGCCCGGGTGAGAGCT
+CAACTCAGACAGCATGTCCCGGTCTTTACCCGACTGACGATCAATGGTCTGGACATGGAT
+GCCACAAAGCAATCGGTGTTACGAAATGGCAAACCGATTTCCCTGACCCGCAAAGAATTC
+CTGCTCCTCTGGTTACTGGCGTCCCGGGCAGGGGAAATCGTGCCCCGAACCGCGATCGCC
+AGCGAAGTTTGGGGAATTAACTTTGATAGTGAAACCAACACCGTTGATGTCGCGATTCGT
+CGGCTGCGCGCCAAAGTAGACGATCCATTTGAAAAGAAGCTCATTATGACCGTCCAGGGG
+ATGGGTTATCGATTACAGGCGGAAACGTCGCAGAATGGTTAAATGAAAAACAAATTGTTA
+TTTATGATGTTGGCAATACTGGGTGCGCCTGGGATTGCAACCGCGACAAATTATGATCTG
+GCTCGTTCAGAGGATAATTTTGCGGTAAATGAATTAAGCAAGTCTTCATTTAATCAGGCG
+GCCATTATTGGTGAAGTCGGCACGGATAATAGTGCCAGAGTACGCCAGGAAGGATCAAAA
+CTATTGTCCGTTGTTTCACAAGAAGGAGAAAATAATCGGGCGAAAGTCGACCAGGCAGGG
+AATTATAACTTTGCGTATATTGAGCAAACGGGCAATGCCAACGATGCCAGTATATCGCAA
+AGCGCTTACGGTGATAGTGCGGCTATTATCCAGAAAGGTTCTGGAAATAAGGCCAATATT
+ACCCAGTACGGTGCGCAGAAAACAGCAGTTGTAGTGCAGAAACAGTCGCATATGGCTATT
+CGCGTCACCCAAGGCATGCATACTTTATTGCTCCTTGCCGCACTTTCAAATGAGATTACG
+TTTACCACGACTCAGCAAGGCGATATTTACACGGTGATCCCTCAGGTCACAGTAAACGAA
+CCCTGCGTCTGTCTGGTGCAAATTCTCTCTGTGCGCGACGGCGTCGGGGGAGAAAGCCAT
+ACACAGCAAAAACAAACGCTATCTTTACCTGCTAATCAACCGATTGAGTTGGCTCGTCTT
+AGTGTAAATATATCTTCAGAGGACTCGGTTAAAATTATTGTTACTGTTTCGGACGGACAA
+TCACTGCATTTATCACAACAATGGCCGCCTTCTGCACAGATGTTTAATGAAGTCCATAGT
+AGTCATGGTCACACACTATTGTTGATCACAAAGCCATCTCTGCAAGCTACGGCATTATTG
+CAACATTTAAAGCAATCGCTGGCCATAACCGGACAACTGCATAATATTCAACGTTCTCTG
+GAAGATATCTCAGCCGGTTGCATTGTTTTAATGCATATGATGGAAGCGGATAAGAAGCTT
+ATCCACTATTGGCAGGATAATTTAAGCCGCAAACACAATAATATAAAAACATTATTGTTA
+AATACCCCTGACGATTATCCCTACCGTGAAATTCAAAACTGGCCTCATATTAACGGCGTG
+TTTTACGCCACTGAAGACCAGGAACACGTGGTCCGCGGATTACAGGGTATTCTGCGGGGC
+GAATGCTATTTTTCACAAAAATTAGCCAGTTACCTGATTACACACTCAGGAAATTACCGC
+TACAACAGCACCGAGTCCGCATTACTCACTCATCGCGAAAAAGAGATCCTCAATAAGTTA
+CGTATTGGTGCCTCTAATAATGAAATCGCCAGGCCGCTATTTATCAGCGAGAATACGGTT
+AAGACACATCTTTATAATCTTTTCAAAAAGATACCTGTCAAAAATCGCACCCAGGCAGTT
+TCAATGAAACGCTATCTGACCTGGATTGTAGCAGCAGAGTTACTGTTCGCTACCGGAAAC
+CTCCATGCCAATGAAGTTGAAGTCGAGGTTCCCGGATTGTTAACCGACCATACCGTCTCT
+TCCATAGGACATGAATTCTATCGTGCATTCAGCGACAAATGGGAAAGCGAATACACCGGC
+AACCTGACCATTAATGAAAGACCCAGTGCGCGTTGGGGAAGCTGGATCACCATAACGGTA
+AACCAGGACGTTATTTTCCAGACCTTTTTATTTCCAATGAAAAGAGACTTCGAGAAAACC
+GTCGTCTTCGCATTAGCGCAAACAGAGGAAGCATTAAATCGCCGACAAATAGATCAAACG
+CTCTTAAGTACGAGTGATTTAGCGCGTGATGAATTCATGCGTGTTAAACATGCAGTAGTG
+CTGCTCATGCTTTTTTCGCCATTAACCTGGGCTCGAAATATGACGTTCCAGTTCCGTAAT
+CCTAACTTTGGTGGAAACCCCAATAACGGTTCCCTTTTATTGAATAGCGCCCAGGCGCAA
+AATTCATATAAAGACCCCGCTTATGATAACGATCTTGGTATCGAGACCCCCTCAGCGTTG
+GATAACTTTACGCAGGCTATTCAATCGCAAATTCTGGGCGGCTTGTTGACCAATATTAAT
+ACCGGAAAACCAGGACGTATGGTGACCAATGATCTTATTATCGATATCGCTAATCGCGAC
+GGACAGCTCCAGCTCAACGTCACGGACAGAAAACCGGGAAGAACCTCGACCATCGAAGTG
+TCAGGTTTACAAACTCAGTCAACCGATTTTATGCCGCGCTTACTTATTTTGGTTGCCGTT
+TTATCGTTGAGCGGATGCTTAACTGCCCCGCCGAAACAAGCTGCGAAACCGACATTAATG
+CCCCCCGCACAAAGTTACAAAGATTTGACGCACTTACCTGCTCCCACCGGTAAGATCTTT
+GTTTCGGTATATAACATTCAGGATGAAACGGGCCAATTTAAACCTTACCCGGCAAGTAAC
+TTTTCCACGGCTGTGCCGCAGAGCGCCACCGCTATGTTGGTCACCGCGCTGAAAGATTCG
+CGCTCGTTTATCCCACTAGAACGACAAGGCTTACAGAATCTTTTGAATGAACGGAAAATT
+ATTCCCGCAGCCCAGGAAAACGGCACCGTGGCGATGAATAACCGTATCCCGCTTCAGTCG
+TTGACGGCGGCAAATATTATGGTGGAAGGTTCTATTATTGGTTATGAAAGTAACGTCAAA
+TCCGCCGGGGTCGGCGCAAGATATTTCGGTATTGGCGCCGATACGCAGTATCAGCTGGAT
+CAGACTGCTGTCAACCTGCGCGTGGTTAACGTCAGTACGGGCGAGATCCTTTCTTCGGTG
+AACACCAGTAAAACGATCCTTTCCTATGAAGTACAGGCAGGCGTGTTCCGTTTTATTGAT
+TACCCGCGCTTACTGGAAGGCGAAATCGGCTATACCTCGAACGAACCGGTGATGCTGTGT
+CTGACGTCAGCCATTGAAACCGGCGTTATCTTCCTCATTAATGATGGTATCGATCGCGGA
+CTGTCGGATTTGCAGAATAAAGCGGACAGGCAAAATGATATTCTGGTGAAATACCGTGAG
+CTGTCAGTACCGCCAGAATCCATGTCTATTGCCGTAAATATGAATGACCCGACCAACACG
+GGCGTCAAAACGACGACCGGCAGCGGGTCGATGACCGGAAGCAACGCTGCCGATCTGCAA
+AGCAGTTTCCTGACCTTACTGGTCGCGCAATTGAAGAACCAGGACCCGACTAACCCATTA
+CAAAATAATGAGTTAACGACACAGTTGGCGCAAATCAGTACCGTGAGCGGCATTGAAAAA
+CTGAATACGACGCTGGGGGCTATTTCCGGGCAAATCGATAATAGTCAGTCCCTACAGGCG
+ACCACGCTGATTGGACATGGCGTTATGGTGCCTGGCACCACAATTCTGGCGGGTAAAGGC
+GCGGAAGAAGGGGCCGTGACGTCCACGACGCCGTTTGGCGTGGAATTGCAACAGCCTGCG
+GACAAAGTGACGGCAACCATTACCGATAAAGATGGCCGGGTGGTACGGACGCTGGAGATC
+GGTGAGTTGCGAGCCGGGGTACACACCTTTACCTGGGATGGTAAGCAAACGGACGGAACA
+ACGGTACCGAATGGTTCTTACAACATTGCGATTACCGCCAGCAATGGCGGGACGCAACTG
+GTGGCGCAGCCGCTGCAATTCGCTCTGGTACAGGGCGTGACGAAGGGCAGTAACGGCAAC
+CTGTTGGATCTGGGTACCTACGGCACCACCACACTCGACGAAGTTCGGCAAATAATCTAA
+ATGTCTTTTTCTCAAGCGGTTAGCGGCCTGAACGCTGCGGCCACCAACCTTGATGTTATC
+GGTAATAACATCGCCAACTCCGCCACCTATGGCTTTAAGTCCGGTACGGCATCATTTGCC
+GATATGTTCGCCGGTTCCAAAGTGGGGTTGGGCGTAAAAGTGGCGGGGATTACCCAGGAT
+TTTACCGACGGTACGACAACGAACACCGGGCGCGGGCTGGATGTCGCGATTAGCCAGAAC
+GGTTTTTTCCGCCTGGTAGACAGCAACGGTTCCGTGTTCTATAGCCGCAACGGCCAGTTC
+AAACTGGACGAGAACCGTAACCTGGTCAATATGCAGGGGATGCAGTTGACCGGCTATCCG
+GCCACCGGTACGCCGCCGACCATTCAGCAGGGGGCGAATCCTGCGCCGATCACCATTCCG
+AACACGCTGATGGCGGCGAAATCGACCACCACCGCGTCAATGCAGATCAACCTGAACTCA
+ACGGACCCTGTACCGTCTAAAACGCCCTTTAGCGTGAGTGATGCGGATTCGTATAACAAA
+AAAGGCACCGTCACCGTTTATGACAGCCAGGGTAATGCCCATGACATGAACGTCTATTTT
+GTGAAAACCAAAGATAATGAATGGGCTGTGTACACCCATGACAGCAGCGATCCTGCAGCC
+ACTGCGCCAACAACGGCGTCCACTACGCTGAAATTCAATGAAAACGGGATTCTGGAGTCT
+GGCGGTACGGTGAACATCACCACCGGTACGATTAATGGCGCGACAGCGGCCACCTTCTCC
+CTCAGCTTCCTTAACTCCATGCAGCAGAACACCGGGGCTAATAACATCGTCGCCACCAAT
+CAAAACGGCTATAAGCCTGGCGACCTGGTGAGCTACCAGATTAACAATGATGGCACCGTG
+GTTGGCAACTACTCCAACGAGCAGGAGCAGGTGCTGGGGCAGATTGTGCTGGCTAACTTC
+GCCAACAACGAAGGTCTGGCATCCCAGGGCGATAACGTCTGGGCGGCGACGCAGGCCTCC
+GGGGTAGCGCTGCTGGGGACTGCCGGTTCCGGCAACTTCGGTAAGCTGACGAACGGCGCG
+CTGGAAGCCTCTAACGTGGATTTGAGTAAAGAGCTGGTGAATATGATCGTCGCGCAGCGT
+AACTACCAGTCGAATGCGCAGACCATCAAAACCCAGGACCAGATCCTCAATACGCTGGTT
+AACCTGCGCTAAATGGATCACGCAATTTATACCGCCATGGGGGCGGCCAGCCAGACGCTT
+AACCAGCAGGCGGTAACGGCCAGCAACCTGGCTAATGCCTCAACGCCGGGCTTTCGCGCG
+CAGCTTAACGCGCTACGCGCGGTGCCCGTTGATGGCCTCTCTTTAGCGACGCGCACGTTG
+GTTACGGCGTCGACGCCGGGGGCGGATATGACCCAGGGTCAGTTGGACTACACTTCCCGC
+CCGCTGGATGTTGCGTTACAGCAGGACGGCTGGCTGGTGGTGCAAGCGGCGGATGGCGCT
+GAAGGATATACCCGTAACGGGAATATCCAGGTGGGCCCGACCGGGCAGTTAACCATTCAG
+GGACATCCGGTTATCGGCGAAGGCGGCCCGATTACCGTTCCGGAAGGGTCGGAAATCACC
+ATTGCGGCAGACGGCACGATCTCCGCGCTCAATCCCGGCGACCCGCCAAACACGGTGGCG
+CCCGTTGGGCGGCTGAAGCTGGTCAAAGCGGAAGGCAATGAGGTGCAGCGGAGCGATGAC
+GGTTTATTCCGCCTTACCGCCGAGGCACAGGCTGAACGCGGGGCGGTACTGGCCGCCGAC
+CCGTCAATTCGCATTATGTCGGGCGTGCTGGAGGGCAGTAACGTCAAGCCGGTTGAAGCC
+ATGACCGACATGATCGCCAACGCACGTCGTTTTGAAATGCAGATGAAGGTTATCACCAGC
+GTAGATGAGAACGAAGGGCGAGCTAACCAACTGCTGTCGATGAGTTAAATGATCAGTTCA
+TTATGGATCGCCAAAACCGGTCTGGACGCGCAGCAAACCAATATGGATGTGATTGCCAAT
+AACCTGGCAAACGTCAGCACCAATGGTTTTAAGCGTCAGCGCGCGGTATTTGAAGATCTG
+TTGTATCAGACCATCCGCCAGCCGGGCGCGCAGTCGTCCGAGCAGACGACGCTGCCTTCC
+GGGCTGCAAATCGGTACCGGCGTGCGTCCGGTCGCCACGGAGCGCCTGCACAGTCAGGGG
+AACCTGTCGCAGACCAACAACAGTAAAGATGTGGCGATTAAAGGGCAGGGCTTTTTCCAG
+GTCATGCTGCCGGACGGTACGTCTGCCTATACCCGCGACGGCTCTTTCCAGGTGGATCAG
+AATGGTCAACTGGTGACGGCGGGCGGTTTTCAGGTGCAGCCGGCAATCACCATTCCGGCC
+AACGCGTTAAGCATCACGATTGGCCGCGACGGCGTGGTCAGCGTTACCCAGCAAGGGCAG
+GCCGCGCCGGTTCAGGTCGGGCAGCTTAACCTGACCACCTTTATGAACGACACCGGTCTG
+GAAAGCATCGGCGAGAACCTCTATATCGAAACGCAATCGTCCGGCGCGCCGAACGAAAGC
+ACGCCGGGGCTCAACGGCGCGGGGTTGTTGTATCAAGGGTATGTCGAAACGTCGAACGTT
+AACGTGGCGGAAGAGCTGGTGAACATGATTCAGGTTCAACGCGCCTATGAAATTAACAGT
+AAAGCAGTATCGACGACCGATCAGATGCTGCAGAAACTGACGCAACTCTAAATGGCCCTG
+ATGGTCGCGACGCTGACAGGATGCGCCTGGATACCCGCTAAACCGCTCGTGCAGGGGGCG
+ACCACGGCGCAGCCGATACCTGGCCCGGTACCGGTGGCGAATGGCTCCATATTTCAGTCT
+GCGCAGCCGATTAATTATGGCTATCAGCCGCTTTTTGAAGATCGTCGACCGCGTAATATC
+GGCGATACGCTCACGATTGTGTTACAGGAAAACGTCAGCGCCAGTAAAAGCTCGTCGGCA
+AATGCCAGCCGCGACGGCAAAACCAGCTTTGGTTTTGATACGGTACCGCGTTATCTGCAG
+GGATTATTCGGTAATTCCCGCGCGGATATGGAGGCCTCCGGCGGCAACTCTTTTAATGGT
+AAAGGCGGCGCGAATGCCAGCAATACCTTTAGCGGCACGCTGACCGTGACCGTCGATCAG
+GTTCTGGCCAATGGCAATTTACACGTCGTGGGGGAAAAACAGATCGCGATTAATCAGGGA
+ACGGAATTCATCCGCTTCTCCGGCGTGGTAAATCCACGCACCATCAGCGGTAGCAACTCT
+GTTCCCTCGACACAGGTGGCGGATGCGCGGATTGAATATGTCGGGAACGGCTATATTAAC
+GAAGCGCAAAATATGGGCTGGCTGCAACGTTTCTTCCTTAATTTGTCGCCGATGTAAGTG
+TTTAAAGCTCTTGCAGGAATCGTTCTGGCACTGGTTGCCACTCTGGCGCACGCCGAGCGT
+ATCCGGGATCTGACCAGTGTCCAGGGAGTACGGGAAAACTCGCTGATCGGCTACGGGCTG
+GTGGTCGGGCTGGACGGTACGGGCGACCAGACGACCCAGACGCCATTTACCACCCAGACG
+CTGAATAACATGCTGTCACAACTGGGGATTACGGTCCCCACCGGCACCAATATGCAGTTG
+AAAAACGTGGCGGCGGTGATGGTGACGGCGTCGTATCCGCCTTTTGCGCGACAGGGACAA
+ACGATCGATGTCGTCGTTTCCTCAATGGGGAACGCTAAAAGTCTGCGTGGCGGGACGTTA
+TTAATGACGCCGTTAAAAGGGGTGGACAGCCAGGTGTATGCTCTGGCGCAGGGCAATATT
+CTGGTCGGCGGCGCGGGCGCTTCCGCAGGCGGCAGTAGCGTGCAGGTTAACCAGCTTAAT
+GGCGGGCGCATCACTAATGGCGCGATTATCGAACGCGAGTTGCCGACTCAGTTCGGCGCT
+GGCAACACCATTAATCTGCAATTGAACGACGAAGATTTTACGATGGCGCAGCAAATTACC
+GACGCCATCAACCGCGCCCGCGGTTACGGCAGCGCCACTGCGCTTGATGCGCGAACGGTA
+CAGGTACGCGTGCCCAGCGGCAACAGCTCGCAGGTGCGTTTTCTGGCGGACATTCAAAAT
+ATGGAAGTCAACGTGACGCCGCAGGATGCAAAAGTCGTGATCAACTCGCGTACCGGTTCG
+GTGGTCATGAATCGGGAAGTCACGCTGGATAGCTGCGCTGTGGCGCAGGGCAATTTGTCA
+GTGACAGTCAATCGCCAACTCAACGTCAACCAGCCGAATACGCCATTTGGCGGCGGGCAG
+ACCGTGGTGACGCCACAGACTCAGATAGATTTGCGTCAGAGCGGCGGATCGCTACAGAGC
+GTGCGTTCCAGCGCCAATCTGAACAGCGTAGTGCGCGCGCTGAATGCGCTTGGCGCGACG
+CCGATGGATCTGATGTCGATTTTGCAGTCCATGCAGAGCGCGGGCTGTCTACGCGCCAAA
+CTGGAAATCATCTGAATGATCGGAGACGGTAAATTGCTGGCCAGCGCGGCCTGGGATGCG
+CAATCTCTGAACGAACTGAAAGCGAAAGCGGGCCAGGACCCGGCGGCGAATATCCGTCCT
+GTGGCCCGTCAGGTGGAAGGGATGTTTGTGCAGATGATGCTGAAAAGTATGCGCGAGGCT
+TTACCCAAAGATGGTTTATTCAGCAGCGATCAGACGCGTCTGTATACCAGCATGTATGAC
+CAGCAGATCGCCCAGCAGATGACCGCCGGTAAGGGATTGGGGCTGGCGGATATGATGGTT
+AAACAGATGACGGGCGGGCAGACGATGCCTGCAGATGATGCGCCGCAAGTACCGCTTAAA
+TTCTCCCTGGAGACGGTAAACAGCTATCAAAATCAGGCGCTGACCCAACTGGTGCGCAAA
+GCCATACCGAAAACGCCGGACAGCAGCGATGCGCCGCTCTCCGGCGACAGTAAAGACTTT
+CTGGCCCGGCTTTCGCTCCCGGCGAGGCTGGCCAGCGAACAAAGCGGGGTGCCGCATCAT
+CTGATTCTGGCGCAGGCGGCGCTGGAGTCCGGCTGGGGGCAGCGGCAAATCCTGCGGGAG
+AATGGCGAACCCAGCTATAACGTATTTGGCGTGAAAGCGACCGCCAGTTGGAAAGGGCCG
+GTGACGGAAATCACCACCACTGAATACGAAAATGGCGAAGCGAAAAAAGTGAAAGCGAAA
+TTCCGCGTCTATAGCTCGTATCTGGAGGCGTTATCGGATTATGTCGCGCTGTTAACGCGT
+AACCCACGCTACGCTGCCGTGACCACTGCCGCCACGGCAGAGCAGGGCGCAGTGGCTCTG
+CAAAACGCCGGATACGCCACTGACCCGAATTACGCGCGTAAATTGGCCAGCATGATTCAG
+CAGTTGAAAGCGATGAGTGAAAAGGTCAGCAAAACCTACAGCGCGAATCTCGACAATCTC
+TTTTAAATGTCCAGCTTGATTAATCACGCCATGAGCGGACTTAACGCCGCGCAGGCCGCG
+TTAAATACGGTCAGTAATAACATCAACAATTATAACGTTGCGGGTTATACCCGGCAGACA
+ACTATTCTGGCGCAGGCAAACAGTACGTTAGGGGCTGGCGGCTGGATAGGTAATGGCGTT
+TACGTTTCAGGCGTACAGCGCGAATATGATGCGTTTATCACTAATCAGCTACGCGGCGCG
+CAAAACCAGAGCAGCGGCTTAACCACGCGCTATGAACAAATGTCGAAAATCGACAACCTG
+CTGGCCGATAAATCCAGCTCACTGTCTGGCTCGCTGCAGAGTTTTTTTACCAGCCTGCAA
+ACGTTAGTCAGTAATGCGGAAGATCCTGCGGCGCGTCAGGCGCTGATTGGTAAAGCGGAA
+GGGCTGGTAAACCAGTTCAAAACCACCGATCAGTATCTGCGCGATCAGGATAAACAGGTC
+AATATCGCGATTGGCTCCAGCGTGGCGCAAATCAACAATTACGCGAAGCAGATAGCTAAC
+CTGAACGATCAAATCTCCCGTATGACGGGCGTAGGCGCGGGCGCATCGCCGAACGACCTG
+CTCGATCAACGTGATCAGTTGGTTAGCGAGCTTAACAAGATCGTTGGCGTCGAGGTGAGT
+GTACAGGACGGCGGCACCTATAACCTGACGATGGCCAATGGCTATACGCTGGTGCAGGGG
+TCGACGGCGCGTCAGTTGGCGGCGGTTCCCTCCAGCGCCGACCCGACGCGAACGACTGTC
+GCTTATGTCGATGAGGCCGCCGGTAACATCGAAATTCCGGAAAAGTTGCTGAACACCGGT
+TCGCTCGGCGGGCTACTGACGTTCCGTTCTCAGGATCTGGATCAGACTCGTAATACGCTG
+GGCCAGTTGGCGTTGGCGTTTGCCGATGCGTTTAACGCGCAGCATACCAAAGGTTATGAC
+GCCGACGGCAATAAAGGGAAAGACTTCTTTAGCATTGGCTCGCCGGTGGTATATAGCAAC
+AGTAATAATGCCGATAAAACGGTATCGCTAACCGCTAAGGTGGTCGACAGCACGAAGGTT
+CAGGCGACGGATTATAAGATTGTTTTTGACGGTACAGACTGGCAGGTTACTCGCACTGCG
+GATAACACCACCTTCACGGCAACAAAAGATGCTGACGGAAAACTGGAGATTGACGGTCTG
+AAAGTGACGGTAGGGACTGGCGCACAGAAAAACGACAGTTTTCTTCTCAAGCCGGTCAGC
+AATGCTATCGTCGACATGAACGTTAAAGTGACAAATGAAGCCGAGATTGCGATGGCGTCT
+GAGTCAAAACTCGATCCTGATGTGGATACCGGCGACAGCGATAACCGCAATGGTCAGGCA
+TTGCTGGACTTACAAAACAGCAATGTAGTGGGCGGCAACAAAACCTTTAACGATGCTTAC
+GCCACGTTGGTCAGCGATGTGGGTAACAAAACGTCAACGCTGAAAACCAGCAGCACCACG
+CAGGCGAATGTGGTTAAACAGCTTTATAAACAGCAACAGTCGGTTTCCGGCGTTAACCTC
+GACGAAGAGTACGGCAATTTGCAGCGTTATCAGCAGTATTATCTGGCGAATGCGCAAGTA
+TTGCAGACCGCGAATGCGCTGTTTGATGCGTTATTGAATATTCGCTAAATGCGTATCAGT
+ACCCAGATGATGTACGAACAAAATATGAGCGGCATCACTAATTCTCAGGCCGAATGGATG
+AAGCTGGGCGAGCAGATGTCTACCGGTAAGCGCGTTACCAACCCATCTGACGATCCGATC
+GCCGCGTCGCAGGCGGTAGTACTCTTTCAGGCGCAGGCGCAGAATAGCCAGTACGCCCTG
+GCGCGTACGTTTGCCACCCAAAAAGTGTCGCTGGAAGAAAGCGTACTCAGTCAGGTGACG
+ACGGCGATTCAAACCGCGCAGGAAAAAATCGTCTATGCCGGAAACGGCACGTTAAGCGAC
+GATGACCGCGCGTCGCTGGCGACGGATTTACAGGGGATCCGCGATCAGCTGATGAACCTG
+GCAAACAGCACTGACGGCAATGGTCGCTATATCTTTGCCGGGTATAAAACGGAAGCGGCG
+CCATTCGACCAGGCGACAGGTGGTTATCATGGCGGCGAGAAAAGTGTTACCCAGCAGGTG
+GATTCCGCACGCACGATGGTAATTGGCCATACGGGAGCGCAAATTTTTAATAGCATCACC
+AGCAATGCGGTGCCGGAACCGGATGGCTCGGACTCCGAAAAGAATCTGTTTGTCATGCTC
+GATACGGCAATTGCCGCGCTCAAGACCCCGGTGGAAGGCAATGACGTGGAAAAAGAAAAA
+GCCGCTGCCGCCATTGATAAAACCAATCGCGGCTTAAAAAATTCGCTTAATAACGTCCTG
+ACCGTTCGTGCGGAACTGGGAACGCAACTGAGCGAACTCAGTACGCTGGATTCACTGGGA
+AGCGACCGTGCGCTGGGACAGAAGCTACAGATGAGCAACCTGGTAGATGTGGACTGGAAC
+TCGGTCATTTCCTCCTACGTCATGCAACAGGCGGCATTACAGGCGTCCTATAAAACGTTT
+ACCGACATGCAGGGAATGTCGCTTTTCCAGTTGAACCGGTAAATGGAGATAATTTTTTAT
+CACCCGACATTTAACGCCGCCTGGTGGGTAAATGCGCTGGAGAAGGCTCTCCCACATGCG
+CGCGTTCGTGAATGGAAGGTCGGTGATAACAACCCCGCAGACTATGCGCTTGTATGGCAG
+CCCCCGGTTGAAATGCTGGCCGGAAGACGCTTAAAAGCCGTCTTTGTGCTGGGCGCGGGG
+GTGGATGCAATTCTGAGTAAATTAAATGCGCATCCGGAAATGCTGGACGCCTCCATTCCT
+CTATTCCGTCTGGAAGATACCGGAATGGGCCTGCAAATGCAGGAGTATGCCGCCAGCCAG
+GTATTACACTGGTTCCGTCGTTTCGATGATTATCAGGCGCTGAAAAATCAGGCGCTATGG
+AAACCGTTGCCGGAATATACCCGCGAAGAGTTTAGCGTCGGTATCATAGGCGCAGGGGTA
+CTGGGCGCAAAAGTGGCAGAAAGTCTACAGGCGTGGGGGTTCCCGTTACGTTGCTGGAGT
+CGTAGCCGCAAATCCTGGCCTGGCGTGGAAAGTTATGTAGGGCGTGAAGAACTGCGCGCT
+TTCCTGAACCAGACGCGGGTGCTGATTAATCTGCTGCCGAATACGGCCCAAACGGTAGGA
+ATTATTAATAGCGAATTGTTGGATCAATTGCCGGATGGCGCTTACGTGCTGAATCTCGCG
+CGCGGCGTTCATGTTCAGGAGGCGGATCTGCTGGCTGCGCTTGATAGCGGTAAGCTAAAA
+GGCGCGATGTTGGATGTCTTTAGCCAGGAACCGTTACCGCAGGAAAGTCCATTATGGCGC
+CATCCGCGAGTCGCCATGACGCCGCACATTGCGGCAGTCACCCGTCCGGCGGAAGCCATC
+GATTATATTAGCCGCACCATTACCCAGCTGGAGAAGGGAGAGCCGGTGACGGGGCAGGTG
+GATCGGGCGAGAGGATATTGGATGTCCGTAATCAAGAAAAATATCCCTGCCATAGGCCTG
+TGTATCTGCGCTTTTTTTATCCATTCTGCGGTAGGGCAACAAACGGTACAGGGCGGCGTT
+ATCCATTTTCGCGGCGCGATTGTTGAGCCACTGTGCGATATTTCTACTCACGCCGAAAAT
+ATTGATTTAACCTGCCTACGCGAAGGTAAAAAGCAAATGCACCGGATAGACCTTCGGCAG
+GCATCTGGATTACCGCAGGATATTCAGTCCATTGCGACGGTACGGCTGCATTATCTCGAT
+GCGCAAAAAAGCCTGGCGGTGATGAATATTGAGTACCGTTAAATGGCAAACCATCGTGGC
+GGTTCCGGTAATTTTGCGGAAGACCGCGAAAGAGCATCAGAAGCAGGTCGTAAAAGTGGT
+CAGCACAGCGGGGGCAATTTTAAGAATGACCCGCAGCGTGCATCCGAAGCAGGCAAAAAA
+GGGGGCAAAAGCAGTAACCGTAATCGCTAGATGGTAATGTCCGCACCAGGACACATTGTT
+TACAGTAGTTACAACACCCTGTACGGACATTCTCTCTCCGGTGGTGGTCTTGTCATCTTA
+AAAGCTCTCATCATTTCCCTTACTGTCCATACCCATGACGCCATATGTGGTGCGCGTAGC
+CGTGTGTGGCGTCGTTTCAAAAAGCAAGCTAAGGCTTACAAGGAAGCCAACCCTCAGATG
+TGTGTGCGCATAATCGCGTTCAAGAGAACGCGGGTGATGTATACCTACAACTCAAGGTGC
+TATCCATGGGAAGACAAAAAGCAGTGAATGAAACGAATTTTCCTTACCTGCGCGGCGTTG
+TTGTTCAGCAGTCAGGCGTTGGCCGATGAGTGTGCCAGCGCCAGTACGCAGCTGGAAATG
+AATCGCTGCGCCGCCGCGCAATACCAGGCGGCAGATAAAAAGCTGAACGAAACCTATCAA
+AGCGCGATTAAGCGTGCGCAACCGCCGCAGCGTGAGCTATTGCAAAAAGCGCAGGTGGCA
+TGGATTGCCCTGCGCGACGCCGATTGCGCGCTGATTCGCTCAGGTACGGAGGGCGGCAGC
+GTTCAACCCATGATCGCCAGCCAGTGCCTGACCGATAAAACGAACGAACGCGAAGCGTTT
+TTAGCCTCGCTGCTGCAATGTGAAGAGGGTGATTTGAGCTGCCCACTGCCGCCAGCCGGT
+TAAGTGCGTATATTCGCGGTGAGCATAATGGTGATTACCCTGAGCGGCTGCGGCAGTATT
+ATCAGCAGAACGATCCCCGGACAAGGACACGGCAACCAGTATTACCCTGGCGTGCAGTTG
+GATATGCGTGATTCCGCATGGCGCTATATCACTATCCTCGATCTGCCCTTCTCACTGATC
+TTCGATACACTGCTACTGCCGCTCGATATTCACCACGGGCCTTATGAGATGTGCCAACGT
+GCGATCGCCAATATTGATATCAGCAAAGAGTATGACGAAAGCATGGGCAGTAACGATGTG
+CATTATCAGTCGTTTGCTCGTATGGCGGATTTCTTTGGTCGTGATATGCAGGCGCATCGC
+CACGACCAGTTTTTTCAAATGCACTTTCTTGATACCGGGCAGATTGAGCTACAGCTCGAC
+GATCATCGCTATTCGGTGCAGGCGCCGCTATTTGTGCTAACGCCGCCCTCGGTGCCGCAT
+GCTTTTATTACCGAATCGGATAGCGATGGTCATGTTCTGACGGTACGCGAAGAGCTGGTT
+TGGCCGCTGCTGGAAGTGCTTTATCCCGGCACCAGAGAGGCCTTCGGCCTGCCGGGAATC
+TGCCTGTCGCTGGCGGATAAACTCAACGAGCTGGCGGCGCTCAAACATTACTGGCAGCTA
+ATTGAGCGGGAGTCCACGGAACAACTGGCTGGCTGCGAACATACCTTGGTACTACTGGCG
+CAGGCGGTATTTACCTTGCTGTTGCGTAATGCGAAGCTGGACGATCATGCCGCAACCGGG
+ATGCGCGGTGAACTGAAACTTTTTCAGCGCTTTACCCTGTTAATTGACAACCACTTCCAT
+CAGCACTGGACGGTGCCCGATTATGCCTGTGAGTTGCATATTACCGAATCTCGTTTGACC
+GATATTTGCCGACGTTTTGCTAATCGCCCGCCTAAACGCCTGATTTTTGATCGGCAATTA
+CGCGAGGCGAAACGACTGCTGCTTTTTTCCGACAATGCTGTCAACGAGATCGCCTGGCAA
+TTAGGTTTTAAAGATCCGGCTTATTTCGCCCGTTTCTTTAATCGCCTTGCTGGCTGTTCT
+CCTTCGCAGTTTCGCCAACGTGAAGTTCCTTCTTTTCTCAACTAAATGGGACGCACACCG
+GATTACAAAGCCGCCTTTGGCTGCGCTCTGGGCGCTAACCCAGCCTTCTACGGCCAGTTT
+GAGCAGAACGCCCGTAACTGGTACACCCGTATTCAGGAGACCGGCCTGTACTTTAACCAT
+GCAATCGTCAACCCGCCCATTGACCGCCACAAACCTGCCGACGAAGTGAAAGACGTCTAT
+ATCAAGCTGGAGAAAGAGACGGACGCCGGGATTATTGTCAGCGGGGCGAAAGTTGTCGCC
+ACTAACTCCGCCCTGACTCACTACAACATGATTGGTTTCGGCTCAGCCCAGGTGATGGGC
+GAAAACCCGGATTTTGCTCTGATGTTTGTCGCGCCAATGGATGCCGAAGGCGTAAAACTT
+ATTTCGCGCGCCTCGTATGAAATGGTCGCGGGCGCGACGGGCTCGCCGTTTGATTATCCC
+CTCTCCAGCCGTTTTGATGAAAACGATGCCATTCTGGTGATGGACAAGGTGCTGATCCCG
+TGGGAAAACGTATTAATTTACCGTGATTTCGATCGTTGTCGTCGCTGGACGATGGAAGGC
+GGCTTTGCCCGTATGTATCCACTGCAAGCCTGTGTTCGTCTGGCGGTAAAACTTGATTTC
+ATTACCGCGCTGCTGAAAAAATCGCTCGAATGTACGGGTACCGTAGAGTTCCGGGGCGTG
+CAGGCCGATCTCGGCGAAGTCGTGGCCTGGCGCAATATGTTCTGGGCATTGAGCGATTCT
+ATGTGTTCTGAAGCAACCCCGTGGGTAAACGGCGCCTGGCTACCGGACCACGCCGCGCTG
+CAAACCTATCGTGTGATGGCCCCAATGGCCTACGCGAAAATTAAAAATATTATTGAACGT
+AACGTTACCAGCGGCCTGATTTACCTGCCTTCCAGCGCCCGCGATCTGAATAATCCGCAA
+ATCGACCAGTACCTGGCGAAATACGTACGCGGCTCTAACGGAATGGACCATGTTGAACGT
+ATCAAAATTCTTAAATTGATGTGGGATGCCATCGGCAGCGAGTTTGGCGGTCGCCATGAG
+CTGTACGAGATTAACTACTCGGGCAGCCAGGATGAAATTCGTCTGCAGTGTCTGCGTCAG
+GCCCAGAGCTCCGGCAATATGGATAAGATGATGGCAATGGTCGATCGCTGCCTCTCCGAA
+TACGATCAGAATGGCTGGACGGTTTCGCATTTGCACAATAACGACGACATCAATCAACTG
+GATAAGCTGCTGAAATAAATGCAAGTAGATGAACAACGTCTGCGTTTTCGCGATGCGATG
+GCAAGTCTGGCGGCAGCGGTCAACATCGTAACCACGGCGGGTCACGCCGGACGCTGCGGT
+ATCACCGCAACAGCGGTTTGCTCAGTCACTGATACGCCGCCCTCCGTGATGGTATGTATT
+AATGCCAATAGCGCCATGAACCCCGTTTTTCAGGGCAACGGCAGGCTGTGCATTAATGTA
+CTTAACCATGAGCAGGAGCTGATGGCGCGCCACTTTGCCGGTATGACGGGGATGGCGATG
+GAGGAGCGTTTTCACCAGCCATGTTGGCAAAACGGGCCGCTGGGCCAGCCGGTACTTAAC
+GGCGCGCTGGCCAGTCTTGAAGGCGAGATCAGCGAGGTACAAACCATTGGCACGCATCTG
+GTGTATCTGGTGGCGATCAAAAATATTATTCTTAGCCAGGAGGGGCATGGCCTGATTTAT
+TTCAAACGCCGTTTTCATCCGGTCAGACTTGAGATGGAAGCGCCTGTTTAAATGAAGGGT
+ACTGTTTTCGCCGTTGCGTTAAACCATCGCAGCCAGCTTGATGCCTGGCAAGAGGCTTTC
+TCTCAGCCTCCCTATAATGCGCCGCCTAAAACCGCAGTGTGGTTCATCAAGCCGCGTAAT
+ACGGTGATTCGTCACGGCGAACCCATTCCTTATCCGCAGGGAGAAAAGGTACTGAGCGGC
+GCGACAGTGGCGCTCATTGTGGGGAAAACCGCCAGCCGGATACGCCCTGAAGCGGCGGCG
+GACTATATCGCCGGGTATGCGCTGGCTAACGAGGTCAGCCTGCCGGAAGAGAGCTTTTAT
+CGCCCGGCGATTAAAGCGAAATGTCGCGATGGCTTTTGCCCGCTGGGTGAAATGGCGCCG
+CTGAGTGATGTGGATAATCTCACCATTATCACTGAAATCAACGGACGAGAAGCGGACCAC
+TGGAATACTGCCGATTTACAGCGTAGCGCCGCACAACTGCTTAGCGCGTTAAGTGAGTTC
+GCTACACTTAACCCTGGCGATGCGATCTTACTTGGTACGCCGCAGAATCGCGTTGCGCTG
+CGTCCCGGCGATCGGGTGCGTATTCTGGCGAAAGGTTTACCCGCGCTGGAAAATCCGGTT
+GTCGCAGAAGATGAATTCGCCCGCCACCAGACGTTTACGTGGCCGCTGTCAGCGACGGGA
+ACGTTATTTGCGCTGGGGTTGAACTACGCCGATCACGCCAGCGAGCTGGCATTTACGCCG
+CCGAAAGAGCCGCTGGTATTTATCAAAGCGCCAAACACCTTTACCGAACATCACCAAACG
+TCGGTGCGCCCGAACAACGTCGAATATATGCACTACGAAGCCGAGCTGGTCGTGGTGATT
+GGCAAAACGGCGCGTAAGGTGAGCGAAGCCGAAGCCATGGAGTATGTGGCCGGTTACACC
+GTCTGTAACGACTACGCGATCCGCGACTATCTGGAAAACTACTACCGTCCGAATCTGCGG
+GTAAAAAGCCGCGACGGCCTGACGCCGATAGGCCCGTGGATTGTGGATAAAGAGGCGGTT
+TCTGATCCGCACAACCTGACGTTACGCACCTTTGTCAACGGTGAGCTGCGGCAGGAAGGG
+ACGACCGCCGATCTGATCTTCAGCATCCCGTTCCTGATTTCTTATCTGAGCGAATTTATG
+ACGTTGCAACCGGGCGACATGATTGCCACCGGTACGCCGAAAGGGCTGTCCGATGTGGTG
+CCGGGGGATGAAGTTGTCGTTGAAGTAGAAGGCGTGGGTCGCCTGGTTAACCGAATCGTC
+AGTGAGGAGAGCGCAAAATGAATGAAAAATGCTTTCAAAGACGCGTTAAAAGCGGGGCGC
+CCGCAAATCGGTTTGTGGCTGGGGCTTGCCAACAGTTACAGCGCTGAACTGTTAGCGGGC
+GCCGGCTTCGACTGGCTACTGATTGACGGTGAACACGCGCCAAACAACGTGCAGACGGTG
+TTGACCCAGTTGCAGGCGATTGCGCCTTATCCCAGCCAGCCGGTGGTGCGTCCGTCATGG
+AACGATCCGGTACAGATTAAGCAACTGCTCGACGTCGGCGCGCAAACGCTGCTGATACCG
+ATGGTGCAGAATGCCGATGAAGCGCGAAACGCCGTGGCGGCTACGCGTTATCCGCCTGCC
+GGTATTCGCGGCGTGGGCAGCGCGCTGGCGCGGGCATCGCGCTGGAATCGCATTCCGGAC
+TATCTCCACCAGGCCAACGACGCCATGTGCGTACTGGTGCAGATTGAAACGCGTGAGGCG
+ATGAGCAATCTGGCGTCAATTCTCGACGTGGATGGCATTGACGGCGTGTTTATTGGCCCG
+GCGGATCTCAGCGCCGATATGGGCTTTGCCGGCAATCCGCAGCACCCGGAAGTGCAGGCG
+GCGATTGAGAACGCCATCGTGCAGATACGCGCGGCGGGGAAAGCGCCGGGGATTCTGATG
+GCCAATGAAGCACTGGCGAAACGTTATCTGGAACTGGGGGCGCTATTTGTCGCCGTCGGC
+GTTGACACCACGCTGCTGGCGCGCGGAGCGGAGGCGCTGGCGGCGCGCTTTGGCGCAGAA
+AAAAAACTGTCCGGTGCGTCCGGCGTCTATTAAATGCATGATTCATTAACCATCGCCTTG
+CTTCAGGCGCGCGAAGCGGCAATGACCTATTTCCGCCCCATCGTTAAAAGCCACAATCTG
+ACCGACCAGCAATGGCGCATTGTGCGAATCCTGGCCGATAGCCCCTCTATGGATTTTCAC
+GAGCTGGCCTTTCGTACCTGTATTTTGCGTCCAAGTCTGACCGGAATATTGACGCGCATG
+GAGCGAGACGGACTGGTGTTGCGACTCAAGCCGGTTAACGATCAGCGTAAGTTATATGTC
+ATGTTGACGGAGCAGGGACAAACGTTGTACGCCCGTGCCCGGAGCGAGGTAGAAGAGGCT
+TATCGAAAAATTGAGGCCGATTTCACGCCCGAAAAAACACAGCAATTGATGCTGCTGCTG
+GACGATCTTATTGCTCTGGGGCGCCAGCATCCTGATAGCGAAGCGGAAGCATAGATGAGC
+GACACATCATCTGCACTTCCGGAAAGCCCCGAGTCTGTCGGTTCGCACAACGCGCTCAGC
+ACGGGTCAACAAACCGTCATAAATAAACTGTTCCGCCGACTGATCGTATTTTTATTCGTG
+TTGTTTATCTTCTCGTTTTTAGACCGTATCAACATCGGTTTTGCCGGGTTGACGATGGGG
+CAGGATCTGGGGTTAAGCGCCACCATGTTTGGTCTTGCCACGACGCTGTTTTACGCCACC
+TACGTCATTTTCGGCATTCCCAGCAACGTGATGTTGAGCATCGTCGGCGCCCGCCGCTGG
+ATTGCGACCATTATGGTGCTATGGGGCATTGCATCTACCGCCACGATGTTCGCGGTGGGA
+CCGAAAAGCCTGTATGTGCTGCGAATGCTGGTGGGCATTACCGAAGCGGGCTTTTTGCCA
+GGAATATTGCTCTATTTAACCTACTGGTTCCCGGCATTTTTCCGCGCCCGCGCCAACGCA
+TTATTTATGATTGCCATGCCGGCCACTACCGCGTTGGGGTCAATTGTCTCCGGCTATATT
+TTATCGCTGGACGGCATATTCAATCTGCATGGATGGCAGTGGTTATTCCTGTTGGAAGGA
+TTTCCGTCAGTTTTGTTAGGCATTATGGTCTGGTTTTACCTGGATGATACCCCGGCAAAA
+GCCAAATGGCTGACGGCAGAGGATAAAAAATGTTTGCAGGAGATGATGGATAATGATCGC
+CTGACGCTGGTTCAGCCTGAGGGGGCCATCAGCCATAACGCCATGCAGCAGCGTAGCCTG
+TGGCGCGAAGTATTCACGCCAATTGTACTGATGTATACGCTGGCCTATTTTTGCCTTACC
+AATACGCTTAGCGCCATTAGTATCTGGACGCCGCAAATCCTGAAAAGTTTTAATGAAGGC
+AGCAGCAATATCACCATCGGCCTGCTGGCGGCGATCCCGCAGATTTGTACTGTTCTGGGC
+ATGATTTACTGGAGCCGCCATTCGGACAAACATCAGGAGCGTAAACACCACACTGCGTTA
+CCGTTCCTGTTTGCCGCCGCGGGCTGGCTGCTGGCGTCGGCGACCGACCGTAACCTGATC
+CAGCTCCTGGGGATCGTGATGGCATCCACGGGTTCCTTTAGCGCGATGGCGATCTTCTGG
+ACCACGCCGGATCAGTCGATCAGTTTACGCGCCAGGGCGATAGGCATTGCGGTCATCAAT
+GCCACCGGCAATATTGGCTCCGCGCTCAGCCCGGTTATGATTGGCTGGCTAAAAGATATC
+ACTGGTAGCTTCAATAGCGGACTCTGGTTTGTCGCTTCTCTGTTAGTCGTCGGCGCCGCC
+ATTATCTGGCTCATTCCCATGAAAGCATCGCGTCCGCGCGCCACCCCTTGAATGGGCAAG
+TTAGCGTTAGCAGCAAAAATTACCCACGTGCCGTCGATGTATCTTTCTGAACTGCCAGGA
+AAAAATCACGGTTGTCGTCAGGCAGCCATTGATGGGCATATTGAAATTGGCAAGCGTTGC
+CGCGAAATGGGCGTTGACACCATTATCGTATTCGACACCCACTGGCTGGTGAATAGCGCT
+TACCACATTAATTGTGCCGACCATTTCCAGGGCGTCTATACCAGCAACGAATTGCCGCAC
+TTTATTCGCGACATGACCTATGACTATGACGGTAATCCGGCGCTCGGCCATCTGATCGCC
+GACGAGGCGGTCAAACTGGGCGTGCGCGCCAAAGCGCACAACATCCCGAGCCTGAAGCTG
+GAGTATGGCACGCTGGTGCCGATGCGCTACATGAACAGCGACAAGCACTTCAAAGTGGTC
+TCCATCTCGGCGTTCTGCACTGTGCATGATTTTGCCGACAGCCGCAAACTGGGCGAAGCC
+ATTCTCAAGGCGATTGAGAAATATGACGGTACCGTAGCGGTATTCGCCAGTGGTTCTCTG
+TCGCACCGTTTTATTGACGACCAACGGGCGGAAGAGGGGATGAACAGCTACACCCGCGAG
+TTCGATCATCAAATGGACGAGCGCGTGGTCAAGCTGTGGCGCGAAGGCAAATTCAAGGAG
+TTTTGCACCATGTTGCCGGAGTACGCCGACTACTGCTACGGCGAAGGCAACATGCACGAC
+ACGGTCATGCTACTGGGAATGCTGGGGTGGGACAAATACGACGGCAAGGTGGAGTTCATC
+ACCGACCTGTTCGCCAGCTCCGGTACCGGCCAGGTAAACGCTGTTTTCCCGCTGCCTGCG
+TAAATGAAGAAAATAAATCATTGGATTAACGGCAAAAACGTTGCAGGTAACGACTACTTC
+CAGACCACTAACCCGGCGACCGGTGATGTGCTGGCGGAAGTAGCCTCCGGCGGTGAAGCA
+GAAGTGAACCAGGCTGTCGCGGCGGCAAAAGAGGCGTTCCCGAAATGGGCCAACCTGCCG
+ATGAAAGAGCGCGCGCGCCTGATGCGCCGCCTTGGCGACCTGATTGACCAGCATGTGCCG
+GAAATCGCGGCGATGGAAACCGCCGACACCGGCCTGCCTATTCACCAGACTAAAACGTGC
+TGAGTGCTGATCCCGCGCGCCTCGCATAACTTCGAATTCTTCGCCGAAGTGTGCCAGCAG
+ATGAACGGCAAGACCTATCCGGTTGACGATAAAATGCTCAATTATACGCTGGTGCAGCCC
+GTCGGCGTCTGCGCGCTGGTGTCGCCGTGGAACGTGCCGTTTATGACCGCGACTTGGAAA
+GTTGCGCCGTGCCTGGCGCTGGGTAACACCGCGGTGCTCAAAATGTCCGAGCTGTCGCCG
+CTGACTGCCGACAGGCTGGGCGAGCTGGCACTGGAGGCAGGAATTCCGGCAGGCGTGCTG
+AACGTGGTGCAGGGCTACGGCGCGACGGCGGGCGATGCGCTGGTACGCCACCATGACGTG
+CGTGCGGTGTCGTTTACCGGCGGTACCGCCACCGGTCGCAATATCATGAAAAATGCCGGG
+CTGAAAAAATACTCGATGGAGCTGGGCGGCAAATCGCCGGTGCTGATTTTTGAAGACGCC
+GACATTGAGCGCGCGCTGGACGCCGCGCTGTTCACCATCTTCTCGATCAACGGCGAACGC
+TGCACCGCTGGGTCGCGCATCTTTATCCAGCAGAGCATTTACCCTGAGTTCGTGAAGCGC
+TTTGCCGAACGCGCGAATCGCCTGCGTGTCGGCGATCCGACCGACCCGAACACCCAGGTC
+GGCGCGCTGATTAGCCAACAGCACTGGGAGAAAGTCTCCGGTTATATCCGCCTCGGCATT
+GAAGAGGGGGCAACGCTGCTGGCGGGCGGTGCGGAAAAACCCACTGACCTGCCTGCGCAT
+CTGAAAGGCGGTAACTTCCTGCGCCCAACCGTGCTGGCCGATGTCGACAACCGTATGCGC
+GTTGCGCAGGAAGAGATCTTTGGGCCGGTCGCCTGCCTGCTGCCATTCAAAGACGAAGCG
+GAAGGGTTACGTTTGGCGAACGATGTGGAATACGGTCTGGCCTCTTATATCTGGACCCAG
+GACGTGAGCAAAGTGTTGCGCCTGGCGCGTGGGATTGAAGCCGGCATGGTCTTCGTCAAC
+ACCCAGAACGTCCGCGACCTGCGCCAGCCGTTCGGCGGCGTGAAAGCCTCCGGTACCGGG
+CGCGAAGGCGGCGAATATAGCTTCGAAGTGTTTGCGGAAATGAAAAACGTCTGCATCTCA
+ATGGGCGACCATCCTATCCCAAAATGGGGAGTTTGAATGCCGCACTTTATTGCTGAATGT
+ACTGAAAATATTCGCGAGCAGGCTGATTTACCAAGCCTGTTCAGCAAGGTAAACGAGGCG
+CTGGCCGCCACCGGGATTTTCCCCATCGGCGGTATCCGCAGTCGCGCCCACTGGCTGGAT
+ACCTGGCAGATGGCTGACGGTAAGCATGATTACGCGTTTGTGCATATGACGCTGAAAATC
+GGCGCCGGGCGCAGCCTGGAGAGCCGTCAGGAAGTCGGCGAAATGCTGTTTGGGCTGATT
+AAAGCCCACTTCGCCGACCTGATGGAGAACCGCTATCTGGCGCTGTCGTTTGAGATTGCC
+GAGTTACATCCAACGCTCAATTACAAACAAAACAACGTACACGCGTTATTTAAATAGATG
+CTCGATAAACAGACCCATACCCTGATCGCTCAGCGACTTAATCAGGCTGAAAAACAGCGT
+GAACAGATTCGCGCAGTGTCGCTGGATTATCCCAACATCACTATTGAAGATGCCTATGCC
+GTACAGCGTGAATGGGTCAATATCAAGATTGCCGAAGGGCGCACGCTCAAAGGCCACAAA
+ATCGGCCTGACCTCAAAAGCGATGCAGGCCAGCTCGCAAATCAGCGAACCGGATTACGGC
+GCGCTGCTTGACGATATGTTCTTCCATGACGGCGGAGATATCCCCACCGACCGTTTTATC
+GTCCCGCGTATTGAAGTGGAGCTGGCGTTCGTGCTGGCGAAACCGCTGCGCGGCCCTCAC
+TGCACGCTGTTCGACGTCTACAACGCCACGGATTATGTGATTCCGGCGCTGGAACTGATT
+GACGCCCGCAGCCACAACATCGACCCGGAAACCCAGCGCCCGCGCAAAGTGTTCGACACC
+ATTTCCGACAACGCCGCCAACGCCGGGGTGATCCTCGGTGGTCGCCCCATCAAACCAGAC
+GAGCTGGATCTGCGCTGGATCTCCGCGCTGCTCTATCGCAACGGCGTGATCGAAGAAACC
+GGCGTCGCCGCAGGCGTGCTGAATCATCCGGCCAACGGCGTGGCGTGGCTGGCGAACAAG
+CTTGCCCCCTACGATGTCCAGCTTGAAGCCGGGCAGATCATCCTCGGCGGCTCGTTCACC
+CGCCCGGTGCCGGCGCGCAAGGGCGACACCTTCCATGTCGATTACGGCAACATGGGCGCG
+ATCAGTTGCCGGTTTGTGTAAATGAGCTCTGTACCCGCGCCGCGTGAATATTTTCTTGAC
+TCTATCCGCGCATGGCTGATGTTGTTAGGGATTCCCTTTCATATCTCGTTGATCTATTCC
+ACTCACAGTTGGCATGTCAATAGCGCCGCGCCATCGTGGTGGCTAACCCTGTTTAACGAT
+TTTATCCACGCTTTTCGTATGCAGGTGTTTTTTGTTATTTCTGGTTATTTTTCGTACATG
+TTATTTTTACGTTATCCATTAAAACACTGGTGGAAAGTACGGGTAGAACGTGTGGGTATT
+CCCATGCTTACCGCAATCCCTTTGCTTACCTTGCCGCAATTTATCCTGTTGCAATATGTC
+AAAGAGAAAACAGAGAACTGGCCTACACTCTCTGCCTATGAAAAATATAATACGTTAGCG
+TGGGAACTCATTTCACATCTGTGGTTTTTACTGGTGCTGGTGATATTAACCACCGTCAGC
+ATCGGGATTTTTACCTGGTTCCAAAAAAGGCAGGAAACAAGCAAGCCTCGTCCCGCCGCT
+ATTTCGCTGGCCAAACTTTCGCTTATTTTTTTCCTGCTGGGGGTGGCGTACGCTGCTATC
+AGGCGCATTATATTCATCGTATATCCGGCAATCCTCAGTGACGGCATGTTCAATTTTATT
+GTGATGCAAACGCTATTTTATGTGCCGTTTTTTATTCTCGGCGCGTTGGCCTTCATTCAC
+CCCGATCTGAAAGCGCGCTTCACCACGCCCTCACGCGGATGCACTTTAGGCGCTGCCGTT
+GCTTTTATCGCGTATCTGCTGAATCAACGTTATGGGAGCGGCGACGCCTGGATGTACGAA
+ACCGAATCCGTGATTACGATGGTAATGGGGCTATGGATGGTGAACGTGGTATTTTCACTG
+GGGCATCGCTTGTTAAACTTTCAGTCCGCGCGTGTCACCTATTTCGTGAATGCTTCGCTG
+TTTATTTATCTGGTGCATCATCCCTTAACGCTTTTCTTTGGCGCGTATATTACACCGCAT
+ATCTCCTCCAACCTGATCGGGTTCTTGTGCGGGCTGATATTTGTTATGGGTATTGCGTTA
+ATTCTGTATGAAATTCATTTACGCATCCCGCTCCTGAAATTTCTCTTTTCAGGTAAACCG
+CCGGTAAAACAAGAAAGCCGCGCCGCGATCGGGTAGATGAAACATAAACGACAAATGATG
+AAAATGCGTTGGTTGGGCGCAGCTATTATGTTAACGCTCTACGCATCATCGAGCTGGGCG
+TTCAGTATTGATGACGTGGCAAAACAAGCTCAATCTTTAGCCGGGAAAGGCTATGAGGCG
+CCTAAAAGCAACTTGCCCTCCGTTTTCCGCGACATGAAATATGCGGATTATCAGCAGATC
+CAGTTTAACAGCGATAAAGCCTACTGGAACAACTTAAAGACCCCTTTTAAGCTCGAATTT
+TACCATCAGGGGATGTACTTCGATACGCCGGTCAAGATTAACGAAGTGACGGCGACGACG
+GTCAAAAGAATCAAATACAGCCCGGATTACTTCAATTTTGGCAATGTTCAGCACGATAAA
+GACACGGTAAAAGATTTAGGCTTCGCCGGGTTCAAAGTCCTGTACCCCATTAACAGTAAA
+GATAAGAACGACGAAATCGTCAGTATGCTTGGCGCCAGCTATTTCCGCGTTATCGGCGCA
+GGCCAGGTGTATGGCTTATCTGCGCGCGGCCTGGCGATTGATACCGCCTTACCATCTGGT
+GAAGAGTTTCCCCGCTTTCGCGAGTTCTGGATTGAGCGTCCAAAACCCACCGATAAGCGT
+TTGACCGTCTATGCATTACTGGATTCTCCGCGCGCGACCGGCGCTTACCGTTTTGTGATC
+ATTCCTGGCCGCGATACCGTGGTGGACGTGCAGTCAAAAGTCTATCTGCGCGATAAGGTG
+GGCAAGCTGGGCGTTGCGCCATTAACCAGTATGTTCCTGTTTGGGCCAAACCAGCCGTCG
+CCGACGACCAACTATCGTCCGGAATTGCATGACTCGAACGGCTTATCCATTCATGCGGGT
+AATGGCGAGTGGATTTGGCGTCCGCTGAACAATCCAAAACACCTCGCTGTGAGCAGCTAT
+GCGATGGAAAACCCTCAGGGATTCGGCCTGTTGCAGCGTGGTCGCGAGTTCTCGCGCTTT
+GAAGATTTAGACGATCGCTATGACCTGCGTCCAAGCGCCTGGATTACCCCGAAAGGCGAC
+TGGGGCAAAGGTAAGGTTGAACTGGTTGAAATTCCGACCAATGATGAAACCAACGATAAC
+ATCGTCGCTTACTGGACTCCGGATCAACTGCCGGAACCGGGTAAAGAGATGAACTTCAAG
+TACACTCTGACCTTCAGCCGCGATGAAGATAAACTTCATGCGCCGGATAATGCCTGGGTG
+CTGCAAACACGCCGCTCAACGGGCGACGTTAAACAGTCGAATCTGATTCGCCAGCCCGAC
+GGCACTATTGCCTTTGTGGTGGATTTCGTTGGCGCCGACATGAAAAAACTGCCGCCGGAT
+ACGCCCGTCGCTGCACAAACCAGCATTGGCGATAACGGTGAAATCGTTGACAGTAATGTA
+CGCTATAACCCAGTCACTAAAGGCTGGCGTTTAATGCTGCGCGTGAAAGTCAAAGACGCG
+AAGAAAACCACGGAAATGCGTGCCGCATTGGTGAATGCCGATCAGACGCTAAGTGAAACC
+TGGAGCTACCAGTTACCTGCCAATGAATAAATGAATAAAACAACTGAGTATATTGACGCA
+CTGCTGCTTTCTGAACGTGAGAAAGCGGCATTGCCGAAAACTGACATCCGCGCCGTGCAT
+CAGGCGCTGGATGCCGAGCATCGGACTTACTCGCGAGAAGACGATTCACCGCAGGGTTCC
+GTAAAAGCCCGCCTTGAACACGCCTGGCCGGATTCATTGGCGAAGGGGCAGTTAATTAAA
+GATGATGAAGGGCGCGATCAGTTGCAGGCTATGCCAAAAGCGACGCGCTCTTCGATGTTT
+CCTGATCCCTGGCGAACCAACCCGGTTGGCCGTTTCTGGGATCGCCTGCGTGGGCGGGAT
+GTTACGCCGCGCTATGTTTCTCGTCTGACAAAAGAAGAGCAGGCGAGTGAGCAAAAATGG
+CGTACCGTCGGCACTATACGCCGCTATATTTTGTTAATTTTGACTCTGGCGCAAACCGTC
+GTTGCGACCTGGTATATGAAGACCATTCTGCCCTATCAGGGATGGGCGCTCATCAATCCT
+ATTGATATGGTGGGGCAGGATATTTGGGTCTCCTTTATGCAGCTCCTGCCCTACATGCTG
+CATACCGGTATCCTGATTTTGTTTGCCGTGCTGTTCTGCTGGGTGTCTGCCGGATTCTGG
+ACTGCGCTGATGGGCTTCCTGCAACTGCTTATCGGGCGCGATAAGTACAGTATCTCCGCG
+TCTACGGTTGGCGATGAGCCCCTCAATCCGGAACACCAGACGGCGCTGATCATGCCTATC
+TGTAATGAAGACGTTAGCCGCGTTTTCGCCGGTCTGCGCGCGACCTGGGAGTCCGTTAAA
+GCTACAGGCAACGCCGCGCATTTTGACGTCTATATCCTTAGCGATAGTTATAACCCGGAT
+ATTTGCGTGGCGGAGCAAAAGGCGTGGATGGAGCTCATCGCGGAAGTGCAGGGCGAAGGC
+CATATTTTTTACCGTCGCCGCCGCCGCCGTATGAAACGCAAAAGCGGCAATATTGACGAT
+TTTTGCCGCCGCTGGGGCAATCAGTACAGCTATATGGTGGTGCTGGACGCGGACTCAGTG
+ATTAGCGGCGAGTGTCTGAGCGGGCTGGTGCGCCTGATGGAAGCGAACCCTAACGCCGGG
+ATTATCCAGTCTTCGCCGAAAGCGTCGGGGATGGATACTCTGTATGCCCGCTGCCAACAG
+TTTGCGACCCGTGTTTATGGACCGCTGTTTACCGCCGGGCTGCACTTCTGGCAGTTGGGG
+GATTCGCACTACTGGGGGCACAATGCCATTATCCGCGTGAAGCCGTTTATCGAGCACTGC
+GCTCTGGCGCCGCTGCCGGGAGAAGGTTCGTTCGCCGGATCGATTCTTTCCCACGACTTT
+GTTGAGGCGGCGCTAATGCGTCGGGCAGGGTGGGGCGTCTGGATTGCCTACGATCTCCCC
+GGTTCCTATGAAGAGCTGCCGCCAAACCTGCTGGATGAGCTTAAACGCGACCGCCGCTGG
+TGTCACGGCAACCTGATGAACTTTCGTCTGTTCCTGGTGAAAGGAATGCACCCGGTGCAT
+CGTGCCGTGTTCCTGACCGGGGTAATGTCATACCTGTCCGCGCCGTTATGGTTTATGTTC
+CTTGCGCTTTCTACCGCGCTGCAGGTCGTTCATGCGTTAACAGAGCCGCAATATTTCCTT
+CATCCGCGCCAGCTTTTTCCGGTCTGGCCGCAGTGGCGTCCGGAACTGGCAATCGCGCTG
+TTTGCGTCAACGATGGTGCTGCTGTTCCTGCCGAAGCTGCTCAGTATTATGCTGATCTGG
+TGTAAAGGCACCAAAGAGTATGGCGGTTTCTGGCGCGTTACGCTGTCGCTATTGCTGGAA
+GTTCTGTTCTCCGTGTTGCTGGCGCCGGTGCGTATGCTGTTTCATACCGTGTTTGTGGTC
+AGTGCGTTCCTCGGCTGGGAAGTGGTCTGGAACTCACCGCAACGCGACGATGATTCTACG
+CCTTGGGGAGAAGCCTTTATGCGTCACGGCTCTCAACTGCTGCTGGGGCTGGTCTGGGCG
+GTTGGTATGGCGTGGCTGGATTTACGCTTTCTGTTCTGGCTGGCGCCGATTGTCTTTTCG
+CTTATTCTGTCGCCATTTGTTTCGGTGATCTCCAGTCGTTCAACGGTAGGATTACGCACC
+AATCGCTGGAAGCTGTTCCTGATCCCGGAAGAGTATTCGCCGCCTCAGGTGTTGGTCGAT
+ACTGATAAATATCTGGAGATGAATCGCCGCCGTATTCTGGACGATGGCTTTATGCATGCG
+GTTTTTAACCCGTCGCTTAATGCGCTGGCGACCGCGATGGCCACCGCGCGTCACCGCGCC
+AGTAAGGTGCTGGAAATAGCCCGCGATCGTCATGTGGAGCAGGCGCTAAACGAAACGCCG
+GATAAACTGAACCGCGATCGGCGTCTGGTTTTGCTCAGCGATCCGGTGACGATGGCGCGT
+TTTCACTATCGGGTCTGGAATGCGCCAGAGAGATACTCTTCCTGGGTAAACCATTATCAG
+TCTCTCGTCCTGAATCCGCAGGCGTTGCAGGGACGAACATCGTCAGCGGGAATGTCGCGC
+GTCTCGNNNGCGAGGAACCTGGGTAAATATTTTCTTCTCATCGATAACATGTTAGTGGTG
+CTGGGTNNNTTCGTCGTCTTCCCGCTCATCTCTATTCGCTTTGTCGATCAAATGGGGTGG
+GCTGCCNNNATGGTAGGGATCGCGCTCGGCCTGCGTCAGTTTATTCAACAAGGTCTGGGC
+ATTTTTNNNGGCGCCATCGCCGATCGCTTTGGCGCGAAACCGATGATTGTCACCGGTATG
+CTGATGNNNGCCGCAGGCTTTGCCACCATGGGTATCGCGCATGAGCCCTGGCTCTTGTGG
+TTTTCCNNNTTTCTTTCCGGTCTCGGCGGTACGCTTTTCGACCCGCCGCGTTCAGCGCTG
+GTGGTCNNNTTAATTCGTCCGGAGCAACGGGGCCGCTTCTTCTCTCTGTTGATGATGCAG
+GACAGCNNNGGCGCGGTGATTGGCGCGCTGCTGGGAAGCTGGTTGCTACAATACGATTTT
+CGCCTGNNNTGCGCGACGGGCGCTATTTTGTTCATATTATGCGCCCTTTTCAACGCATGG
+CTGCTTNNNGCCTGGAAGCTATCAACGGCCAGAACGCCGGTGCGTGAAGGAATGCGCCGC
+GTCATGNNNAATAAAAGGTTTGTCACCTACGTGCTGACGCTGGCGGGCTACTATATGCTG
+GCGGTANNNGTCATGTTAATGCTGCCGATTATGGTAAACGATATCGCCGGTTCGCCTGCT
+GCCGTGNNNTGGATGTACGCTATTGAGGCGTGTCTCTCGCTGACGTTGCTCTACCCGATT
+GCCCGCNNNAGCGAAAAGCGTTTTCGGCTGGAGCATCGGCTGATGGCCGGTTTGCTCGTC
+ATGTCGNNNAGCATGCTCCCCATCGGGATGGTGGGCAATTTACAGCAGCTTTTTACGCTT
+ATTTGCNNNTTCTACATCGGCTCGGTTATCGCCGAACCGGCGCGCGAAACGCTCAGCGCG
+TCGCCCNNNGACGCGAGGGCGCGGGGAAGCTATATGGGCTTTAGCCGTCTGGGATTAGCC
+ATTGGCNNNGCGATTAGTTATATCGGCGGCGGCTGGTTGTTTGATATGGGTAAAGCGCTT
+GCGCAGNNNGAACTACCGTGGATGATGCTCGGTATTATCGGCTTTATCACCTTTTTGGCT
+TTAGGCNNNCAATTTAGTCATAAGCGCACGCCGCGCCGGATGCTGGAACCCGGCGCCATG
+ACCAAGTATGCCACGCTGGAAGAAGCTATCGATGCAGCCCGGGAAGAATTTCTGGCTGAC
+CATCAAGGCCTCGAACAAGACGAAGCGAATGTGCAGCAGTTCAACGTTCAGAAATATGTA
+CTGCAGGATGGGGACATCATGTGGCAGGTCGAATTTTTCGCCGATGAAGGTGAAGATGGC
+GAATATCTGCCGATGCTGAGTGGTGAAGCCGCACAGAGCGTGTTTGACGGCGATTATGAT
+GAGAAAGAGATCCGCCAGGAATGGCAGGAAGAGAATACTTTGCATGAATGGGATGAAGGG
+GAATACCAGCTTGAACCCCCGCTTGATACCGAGGAAGGCCGTACTGCGGCAGACGAATGG
+GATGAGCGTATGTCACTATTAGCCAGGCTGGAACAAAGTGTACACGAAAACGGTGGGCTG
+ATTGTCTCATGCCAACCGGTACCAGGCAGCCCTATGGATAAACCTGAAATTGTGGCTGCA
+ATGGCACAGGCAGCGGCTTCGGCGGGTGCGGTCGCTGTGCGCATTGAAGGCATTGAGAAT
+CTGCGGACTGTTCGTCCCCATCTTTCTGTTCCTATTATTGGGATAATTAAACGTGACCTT
+ACAGGGTCGCCAGTCCGTATCACTCCATATTTACAGGATGTTGACGCCCTGGCGCAGGCA
+GGTGCCGATATTATCGCTTTTGATGCCTCATTCCGCTCTCGCCCGGTTGATATTGATAGT
+TTACTGACACGTATTCGCCTGCATGGATTACTGGCGATGGCAGACTGTTCAACCGTGAAT
+GAAGGCATAAGTTGCCATCAGAAAGGAATCGAATTCATTGGTACAACACTGTCTGGCTAT
+ACCGGTCCCATCACGCCGGTTGAGCCAGATTTGGCAATGGTGACACAACTGAGTCATGCA
+GGTTGTCGTGTTATTGCCGAGGGGCGCTATAACACGCCTGCACTGGCGGCCAATGCTATT
+GAGCATGGTGCCTGGGCAGTTACCGTTGGTTCCGCTATCACCCGTATCGAGCATATCTGT
+CAGTGGTTCAGTCACGCAGTAAAACGCTGAATGAAAAATTTTAAGAAAATGATGACGCTA
+ATGGCGCTATGTTTATCAGTTGCTATCACCACATCAGGATATGCAACCACGCTTCCTGAT
+ATACCAGAACCACTGAAAAATGGTACTGGCGCTATTGATAATAATGGCGTGATTTATGTC
+GGCTTAGGTACCGCAGGGACATCCTGGTATAAAATTGATCTTAAAAAGCAACATAAAGAC
+TGGGAGCGTATAAAGTCGTTTCCTGGTGGAGCTCGTGAGCAATCCGTGTCGGTATTTTTA
+AATGATAAGCTGTATGTTTTTGGTGGCGTAGGGAAAAAAAACAGTGAATCACCGTTGCAG
+GTTTATAGCGATGTGTACAAATACTCACCGGTGAAAAATACATGGCAAAAAGTTGATACT
+ATATCTCCAGTTGGATTAACAGGGCATACGGGAGTAAAATTAAACGAAACGATGGTACTT
+ATTACCGGAGGGGTTAATGAGCATATCTTTGATAAGTATTTTATTGATATAGCGGCTGCG
+GATGAAAGTGAAAAAAATAAAGTCATCTATAATTATTTTAATAAACCTGCCAAAGATTAT
+TTTTTTAATAAAATCGTATTTATCTACAATGCTAAAGAGAACACATGGAAGAATGCCGGT
+GAGCTGCCAGGCGCGGGGACGGCAGGATCGTCATCGGTAATGGAAAATAATTTCTTGATG
+CTGATTAATGGTGAGCTCAAACCGGGTTTACGTACCGATGTGATTTACCGCGCCATGTGG
+GATAACGATAAGCTAACATGGTTGAAGAACAGCCAGTTACCGCCATCGCCTGGAGAACAA
+CAGCAGGAAGGGTTGGCCGGAGCATTTTCGGGCTATAGCCACGGTGTCCTGCTTGTCGGT
+GGTGGCGCGAATTTTCCGGGAGCAAAACAAAATTATACTAATGGAAAGTTTTATTCCCAC
+GAAGGGATAAATAAAAAATGGCGAGATGAAGTCTATGGTTTGATTAATGGCCATTGGCAA
+TATATGGGTAAAATGAAACAACCTCTCGGCTATGGTGTATCAGTAAGTTATGGTGATGAA
+GTTTTCCTTATTGGTGGTGAAAATGCTAAAGGGAAACCTGTTTCGTCTGTAACCTCCTTT
+ACCATGCGTGATGGTAATTTATTAATAAAATAAGTGATAGCAAAATTCTTCCCGTGGTAT
+AGCGAGATAACACGTCCACAAAAAAATGCTTTATTTTCAGCATGGCTGGGTTACGTTTTT
+GATGGCTTCGACTTTATGCTGATTTTCTACATTATGTATCTGATCAAGGCTGACTTAGGA
+TTGACAGATATGGAGGGCGCATTCCTTGCCACAGCGGCCTTTATTGGGCGACCATTTGGC
+GGGGCGCTATTTGGTCTGCTGGCAGACAAATTTGGCCGTAAGCCGTTAATGATGTGGTCG
+ATAGTTGCCTATTCTGTAGGTACAGGGTTAAGTGGCCTGGCTTCCGGTGTAATTATGCTG
+ACGCTTAGTCGTTTTATTGTCGGTATGGGGATGGCGGGGAAGTATGCTTGCGCTTCTACT
+TATGCCGTGGAAAGTTGGCCAAAGCATTTAAAATCTAAAGCGAGCGCATTTCTGGTTTCA
+GGTTTCGGTATTGGTAACATCATAGCAGCCTATTTTATGCCGTCATTTGCCGAAGCGTAT
+GGTTGGCGTGCTGCTTTTTTTGTCGGTTTGCTACCCGTTCTTTTAGTAATCTACATCCGG
+GCCAGGGCTCCTGAATCTAAAGAGTGGGAAGAAGCCAAACTCAGTGGTCTCGGAAAGCAT
+TCACAAAGTGCCTGGTCAGTTTTCTCTTTGTCAATGAAAGGGCTATTTAATCGAGCTCAA
+TTTCCACTGACATTATGTGTATTTATTGTTCTGTTCTCTATTTTCGGCGCAAACTGGCCG
+ATCTTTGGTCTACTGCCTACATATTTGGCGGGAGAGGGCTTTGATACGGGCGTGGTCTCT
+AATTTAATGACGGCGGCGGCATTCGGCACTGTATTGGGAAATATCGTTTGGGGTCTGTGC
+GCAGATAGAATTGGTTTGAAGAAAACGTTCAGCATTGGTCTTCTCATGTCCTTTTTATTC
+ATTTTCCCGTTATTCAGAATTCCGCAAGATAATTATTTACTGCTGGGCGCATGTTTATTC
+GGTTTAATGGCGACTAACGTAGGTGTTGGCGGGCTGGTTCCCAAATTTCTCTACGACTAC
+TTTCCTCTTGAGGTTCGTGGTTTGGGTACCGGGCTTATTTATAATCTTGCTGCGACATCA
+GGCACATTCAATTCAATGGCGGCGACCTGGCTTGGAATAACAATGGGGCTAGGCGCTGCG
+CTAACGTTCATTGTTGCTTTCTGGACCGCAACAATTCTACTCATTATTGGCCTATCCATT
+CCGGATAGACTAAAAGCACGTCGTGAAAGGTTTCAGTCAACAAAAGAATTTTAAATGAAA
+AAGTATCTTGCTTTCGCCGTTACGCTGCTGGGTATGGGTAAAGTCATCGCCTGTACTACC
+CTTTTGGTAGGCAATCAGGCTTCGGCTGACGGCTCCTTTATTATCGCGCGCAACGAGGAT
+GGCTCGGCAAATAACGCCAAGCATAAGGTTATTCATCCCGTCGCGTTTCATCAACAAGGC
+GAGTATAAAGCACATCGCAACAATTTTAGCTGGCCGCTTCCGGAGACAGCGATGCGCTAT
+ACGGCGATTCATGACTTTGATACTAACGATAACGCCATGGGTGAAGCCGGTTTCAATTCG
+GCGGGCGTCGGAATGAGCGCAACGGAAACCATTTACAACGGCAGAGCGGCGCTGGCTGCC
+GATCCTTACGTGACAAAAACGGGAATCACGGAAGACGCCATTGAGTCCGTGATCCTGCCA
+GTGGCGCAATCGGCGCGTCAGGGCGCCAAATTACTGGGAGATATTATTGAACAAAAAGGC
+GCGGGCGAAGGTTTCGGCGTCGCGTTTATTGATAGCAAAGAGATATGGTATCTGGAGACG
+GGAAGCGGACATCAATGGCTGGCAGTACGACTTCCGGCAGATAGCTATTTCGTTTCCGCC
+AATCAGGGACGTTTACGCCATTACGATCCGAATGATAACGCGAATTATATGGCGTCACCA
+ACGTTAGTAAGCTTTGCGAAAAAGCAGGGATTATATGATCCGGCCCGCGGCGAATTCGAC
+TTTCATCAAGCCTATTCGCAGGATAACAAAAACGATACCACCTATAATTATCCGCGCGTC
+TGGACGCTACAACACCAGTTTAATCCGCATCTGGATACGGTCGTTAGCGAAGGGGAAACA
+TTTTCTGTTTTTTTAACGCCAATAACGAAGATCAGCGTGGCGGCAGTAAAAAACGCGTTA
+CGCAATCACTATCAGGGAACGTCGCACGACCCTTATGCCAGTCATAATCCACAAGAACCA
+TGGCGACCTATATCCGTTTTTCGTACCCAGGAGTCACATATTTTACAGGTCAGACCGAAA
+TTACCGCAGGCTATCGGCAACGTAGAATACATCGCCTATGGAATGCCATCTCTTAGCGTC
+TATCTCCCCTATTACCAGGGGATGCGTCATTATCAACCCGGAGATGATAAAGGAACCGAT
+CGGGCGAGCAACGACTCTACCTACTGGACATTCCGCACGCTGCAAACACTGGTTATGCAA
+GACTACAATACGTTTGCGCCAGATGTGCAACATGCCTGGAAAACATTTGAACAGCAAACA
+GCTAAGCAACAGTATAAGATGGAGCAGAGCTATCTGAGATTATATGCGTCGCATCCGAAA
+GAAGCACAACGCTTACTGCAAAATTTTGAAGATAAAACGATGCAAAATGCGCAGACGCTC
+GCCCGTCGCCTGACCAATAATATTATTACGACAATGACTTACCGCACAGATATGAAATAT
+CACTTTTCAAGTACGCAGCCATAAATGGGAAGACAAAAAGCAGTGATCAAAGCTCGTCGT
+GAAGCAAAGCGTGTGTTGAGACGAGATTCGCGTAGTCATAAGCAACGTGAAGAAGAATCG
+GTCACGTCACTGGTACAGATGGGCGGAGTAGAAGCCATTGGCATGGCGCGCGATAGTCGC
+GATACCTCTCCTGTTAAGGCGCGAAATGAAGCACAGGCGCATTATCTGAACGCTATCGAC
+AGTAAACAGCTTATTTTTGCGACCGGCGAAGCCGGCTGCGGAAAAACATGGATCAGTGCG
+GCAAAGGCGGCAGAAGCATTGATTCATAAGGACGTCGAGAGGATCATTGTGACGCGTCCG
+GTATTGCAGGCTGATGAAGATCTTGGTTTTTTGCCCGGTGATATCGCTGAAAAATTCGCG
+CCTTATTTTCGTCCCGTCTACGATGTCCTGCTTAAACGGTTGGGCGCGTCCTTTATGCAA
+TATTGTTTGCGCCCGGAAATCGGTAAGGTAGAAATTGCCCCGTTCGCCTATATGCGTGGG
+CGTACTTTTGAAAATGCGGTCGTGATCCTCGACGAGGCGCAAAATGTGACTGCGGCGCAA
+ATGAAAATGTTTTTGACGCGATTAGGCGAAAATGTCACGGTCATTGTCAATGGCGATATT
+ACGCAATGCGACCTGCCGCGCGGTGTGCGTTCCGGGTTGAGTGATGCGTTGGAACGCTTT
+GAAGAAGATGAAATGGTGGGGATTGTGCATTTCAACAAAGACGACTGCGTGCGCTCGGCG
+CTTTGTCAGCGAACGCTCCACGCATACAGCTAAATGGGAACCACCACGATGGGGGTTAAG
+CTGGACGACGCCACGCGCGAACGGATCAAAATGGCCGCGTCGCGTATCGATCGCACGCCG
+CACTGGTTAATAAAACAGGCAATCTTTAGCTATCTGGACAAGCTGGAAAATAGCGATACG
+CTACCGGAGCTACCTGCGCTGTTTGCCGGCGCGGCAAATGAAAGCGAGGAGCCGGTCGCG
+CCGCAGGATGAGCCGCATCAGCCCTTTCTGGAGTTTGCCGAACAGATTCTTCCCCAATCC
+GTCTCTCGCGCCGCCATCACCGCCGCCTGGCGCCGCCCGGAAACCGATGCGGTGTCAATG
+CTAATGGAACAGGCGCGCCTGTCGCCGCCTGTCGCTGAGCAGGCGCATAAACTGGCGTAT
+CAACTGGCGGAGAAATTGCGCAATCAAAAATCCGCCAGCGGTCGCGCGGGTATGGTGCAA
+GGCCTGTTGCAGGAGTTTTCCCTCTCTTCGCAAGAAGGCGTAGCGCTGATGTGTCTGGCG
+GAAGCGCTGCTGCGTATTCCCGACAAAGCTACGCGCGATGCGTTAATTCGCGACAAAATC
+AGTAATGGCAACTGGCAGTCGCATATTGGCCGTAGCCCGTCGCTGTTTGTAAACGCCGCC
+ACCTGGGGGCTGCTCTTTACCGGCCGACTGGTCTCAACGCATAACGAAGCCAATCTTTCG
+CGCTCGCTGAACCGCATTATCGGCAAGAGCGGCGAACCGTTAATCCGCAAAGGCGTCGAC
+ATGGCGATGCGTTTAATGGGCGAGCAGTTCGTGACTGGCGAAACCATTGCTCAGGCGCTG
+GCGAATGCCCGAAAACTGGAAGAGAAAGGGTTCCGCTATTCTTACGATATGCTGGGCGAA
+GCCGCGTTAACCGCCGCCGATGCGCAGGCCTATATGGTCTCTTACCAGCAAGCGATTCAT
+GCCATCGGCAAAGCGTCTAACGGTCGCGGTATTTACGAAGGGCCAGGCATCTCGATTAAG
+CTGTCCGCCCTGCATCCACGCTATAGTCGCGCGCAATACGATCGGGTAATGGAGGAGCTT
+TATCCGCGCCTGAAATCCCTGACGCTGCTGGCGCGCCAGTATGATATCGGTCTCAATATC
+GACGCCGAAGAGGCGGATCGTCTGGAGATCTCGCTTGATCTGCTGGAAAAACTCTGCTTC
+GAACCCGAACTGGCGGGCTGGAACGGCATTGGCTTTGTGATTCAGGCTTACCAGAAACGC
+TGCCCGCTGGTCATTGATTATTTAGTCGATCTGGCCTCCCGTAGCCGCCGTCGGCTGATG
+ATTCGTCTGGTGAAAGGCGCCTACTGGGATAGCGAGATCAAACGCGCGCAAATGGAAGGG
+CTGGAGGGCTATCCAGTTTATACCCGCAAAGTGTATACCGATGTCTCTTATCTGGCCTGC
+GCGAAAAAACTGCTCGCCGTCCCTAATCTGATCTACCCGCAGTTCGCGACCCATAACGCT
+CACACACTGGCGGCGATTTATCATCTGGCCGGGCAAAATTACTATCCGGGTCAGTACGAA
+TTCCAGTGCCTGCACGGCATGGGAGAACCGCTGTATGAACAGGTCACCGGTAAAGTGGGG
+GACGGAAAACTTAACCGTCCCTGCCGTATTTACGCGCCGGTGGGAACACACGAAACCCTG
+CTGGCCTATCTGGTACGACGCCTGCTGGAAAACGGCGCCAACACCTCTTTTGTCAACCGC
+ATCGCCGATGCCACCCTACCGCTCGATGAACTGGTGGCCGACCCGGTCGAGGCCGTGGAA
+AAACTGGCGCAGCAGGAAGGTCAGGCTGGCATACCGCATCCAAAAATTCCGCTGCCGCGC
+GATCTGTACGGCGAAGGTCGGATAAACTCCGCCGGACTTGATTTAGCGAATGAACATCGC
+CTCGCCTCGCTTTCTTCTGCCCTGTTAAGCAACGCCATGCAGAAATGGCAGGCCAAACCT
+GTGCTGGAACAACCGGTGGCCGACGGTGAGATGACGCCGGTTATCAACCCGGCGGAACCG
+AAAGATATTGTTGGCTGGGGACGCGAAGCGACAGAAAGCGAGGTTGAACAGGCGTTGCAA
+AACGCGGTCAATCAGGCGCCGGTTTGGTTTGCGACGCCGCCGCAAGAACGCGCCGCTATT
+TTGCAGCGGGCGGCGGTATTGATGGAAGACCAAATGCAGCAGTTGATTGGCCTGTTGGTG
+CGTGAAGCGGGGAAAACGTTCAGCAACGCCATTGCCGAAGTGCGCGAAGCGGTAGACTTC
+CTCCATTATTATGCCGGTCAAGTGCGTGACGATTTCGATAACGAAACGCATCGCCCGTTA
+GGGCCGGTGGTCTGTATCAGTCCGTGGAACTTTCCGCTGGCCATTTTCACTGGCCAAATC
+GCCGCCGCGCTGGCGGCAGGTAACAGCGTTCTGGCGAAACCGGCAGAGCAGACATCGCTG
+ATTGCCGCCCAGGGCATTGCCATTTTGCTGGAAGCGGGCGTACCGCCGGGCGTCGTGCAA
+CTGTTGCCGGGACGGGGAGAAACCGTCGGCGCCCAGCTTACCGCCGATGCGCGTGTACGC
+GGCGTGATGTTTACCGGTTCCACGGAGGTCGCGACGTTGTTGCAGCGCAACATCGCCACG
+CGTCTTGACGCCCAGGGGCGCCCTATTCCGTTGATTGCGGAAACCGGCGGTATGAACGCT
+ATGATTGTCGACTCTTCCGCGCTCACCGAGCAGGTGGTCGTGGATGTGCTGGCTTCCGCC
+TTCGACAGCGCCGGACAACGCTGTTCCGCGCTCCGCGTGCTGTGTTTGCAGGACGATATC
+GCCGAACATACGCTGAAAATGTTACGCGGCGCGATGGCGGAGTGTCGGATGGGGAATCCA
+GGCCGTCTGACGACCGATATCGGGCCGGTGATCGATAGCGAGGCCAAAGCCAACATTGAA
+CGTCATATCCAGACGATGCGCGCCAAAGGCCGCCCGGTTTTCCAGGCCGCGCGTGAAAAC
+AGCGATGACGCGCAGGAATGGCAGACCGGTACGTTTGTTATGCCCACGCTTATTGAGCTG
+GAAAACTTCGCAGAACTGGAAAAAGAGGTCTTCGGGCCCGTGCTGCACGTCGTGCGTTAT
+AACCGTAACCAACTGGCGGAGCTTATCGAACAGATTAACGCTTCCGGCTACGGGCTAACG
+CTGGGCGTACATACCCGTATTGATGAAACCATTGCGCAAGTCACCGGTTCCGCCCATGTC
+GGCAACCTGTACGTTAACCGTAATATGGTGGGCGCGGTCGTCGGCGTCCAGCCGTTTGGC
+GGCGAAGGCCTGTCCGGCACCGGGCCAAAAGCGGGAGGGCCGCTCTATCTCTACCGCCTG
+CTGGCACACCGCCCGCCCAATGCGCTCAATACGACGCTGACTCGTCAGGATGCGCGTTAC
+CCGGTGGATGCGCAGCTTAAAACCACGCTACTCGCGCCGTTGACCGCTCTGACGCAATGG
+GCGGCGGATCGCCCGGCGCTACAGACGCTCTGCCGACAATTCGCCGATCTGGCGCAGGCC
+GGCACGCAGCGCCTGCTACCGGGGCCGACCGGCGAGCGTAATACCTGGACGCTGTTGCCG
+CGTGAACGGGTGTTATGCCTGGCTGATGATGAACAGGACGCGTTGACGCAGCTTGCCGCC
+GTTCTCGCCGTCGGCAGTCAGGCGCTATGGTCAGACGACGCCTTCCACCGCGATCTGGCG
+AAACGTCTCCCCGCCGCCGTCGCGGCGCGTGTCCAGTTTGCGAAAGCGGAAACGCTGATG
+GCGCAGCCGTTTGACGCGGTGATTTTCCACGGCGACTCCGACAAGCTGCGAACCGTGTGC
+GAAGCCGTCGCCGCCCGCGAAGGCGCGATAGTGTCGGTACAGGGGTTCGCCCGCGGCGAA
+AGCAATATGCTGCTGGAACGGCTCTATATTGAACGTTCGCTGAGCGTAAACACTGCCGCC
+GCTGGCGGTAATGCCAGCCTGATGACAATTGGCTAAATGGCTATTAGCACACCGATGTTG
+GTGACATTCTGTGTCTATATTTTTGGCATGATATTGATTGGGTTTATCGCCTGGCGCTCA
+ACCAAAAACTTTGATGACTATATTCTTGGCGGTCGCAGCCTGGGGCCGTTTGTTACGGCT
+TTATCAGCCGGCGCGTCGGATATGAGCGGCTGGCTGTTAATGGGGCTGCCTGGCGCTATC
+TTTCTGTCGGGGATCTCTGAAAGCTGGATCGCCATTGGCCTGACGTTAGGCGCATGGATT
+AACTGGAAGCTGGTGGCCGGGCGCCTGCGCGTGCATACCGAATTTAACAATAACGCGCTC
+ACGCTGCCGGACTATTTTACCGGTCGGTTTGAGGATAAGAGCCGAGTCCTGCGTATTATT
+TCCGCGCTGGTCATTCTGCTGTTTTTCACTATCTATTGCGCATCAGGTATTGTCGCTGGG
+GCACGACTGTTCGAAAGCACCTTCGGTATGAGCTATGAAACCGCACTGTGGGCGGGGGCC
+GCGGCAACCATTATTTATACCTTTATCGGCGGGTTTCTTGCCGTTAGCTGGACGGATACC
+GTTCAGGCCAGCCTGATGATTTTTGCGTTAATCCTGACGCCGGTGATGGTTATTGTCGGC
+GTAGGCGGTTTTAGCGAGTCGCTGGAAGTGATCAAGCAAAAGAGCATCGAGAATGTCGAC
+ATGCTCAAGGGGCTGAATTTTGTCGCTATTATTTCTCTGATGGGCTGGGGGCTGGGTTAC
+TTCGGTCAGCCGCATATCCTGGCGCGCTTTATGGCGGCGGATTCCCATCACAGTATTGTT
+CATGCGCGTCGTATCAGTATGACCTGGATGATTCTGTGTCTGGCGGGCGCGGTGGCGGTG
+GGCTTCTTTGGCATTGCGTACTTTAACAATAACCCCGCGCTGGCCGGGGCGGTGAACCAA
+AACTCAGAACGCGTATTTATTGAACTGGCGCAGATCCTGTTTAACCCGTGGATTGCCGGT
+GTTCTGCTGTCTGCTATCCTGGCGGCGGTGATGTCGACGTTGAGCTGTCAGTTGCTGGTA
+TGCTCCAGCGCGATTACGGAAGATTTATATAAGGCTTTTCTGCGTAAAAGCGCCAGCCAG
+CAAGAGCTGGTATGGGTAGGGCGAGTGATGGTGCTGGTGGTAGCGCTGATCGCCATTGCG
+CTGGCGGCGAATCCTGATAACCGTGTGCTGGGGCTGGTGAGCTACGCCTGGGCTGGATTC
+GGCGCGGCATTTGGACCTGTTGTCCTGTTTTCTGTGATGTGGTCGCGTATGACACGTAAC
+GGCGCGCTGGCGGGAATGATTATTGGCGCGGTGACGGTTATCGTCTGGAAACAATATGGC
+TGGCTGGATCTGTATGAGATTATCCCTGGCTTCATTTTCGGCAGCCTGGGGATCGTAATC
+TTTAGCCTGCTTGGCAAAGCGCCGACAGCAACGATGCAGGAACGCTTTGCAAAAGCGGAC
+GCGCATTATCATTCCGCGCCGCCGTCGAAGCTACAGGCGGAATAAATGGCGGGTAAACTG
+CGGCGTTGGCTGCGTGAAGCCGCGGTTTTTCTGGCGCTCCTCATCGCGATAATGGTGGTC
+ATGGACGTCTGGCGCGCGCCGCAGGCGCCTCCGGCGTTTGCCGCGACACCATTACATACG
+CTGACGGGAGAGTCGACAACTCTGGCGACCTTGAGCGAGGAACGCCCCGTACTGCTCTAT
+TTTTGGGCCAGCTGGTGCGGGGTATGCCGCTTTACCACGCCTGCGGTCGCTCACCTGGCG
+GCGGAAGGGGAAAACGTCATGACCGTTGCGCTCCGCTCCGGCGGTGATGCTGAGGTTGCC
+CGCTGGCTGGCGCGCAAGGGCGTTGACTTCCCGGTCGTCAATGATGCTAACGGCGCCTTA
+TCCGCTGGCTGGGAAATCAGCGTGACGCCAACGCTGGTGGTGGTTTCACAAGGTCGGGTT
+GTGTTCACCACCAGCGGCTGGACCAGCTATTGGGGCATGAAGCTTCGGCTGTGGTGGGCA
+AAAACGTTCTGAATGATGAAAAAAAGCGTCGCTATGCTGGCGGTTTGTATGCTGGCGCAA
+AGCCACCTTGCCATTGCTGCCGGTGCTCCTGCGCCTCAAGAGATCAACATTGTTTTACTG
+GGCACCAAAGGCGGGCCTTCTTTGCTCAATACAGCCAGACTACCGCAAGCGACGGCGCTC
+ACTATCGGCGATAAGATATGGCTGATAGATGCCGGCTACGGCGCCAGTCTGCAACTGGTG
+AAAAATGGCATTCCACTGCGCAACATCAATACTATTTTGCTCACCCATCTGCACAGCGAC
+CACATACTGGATTATCCTTCCTTGCTGATGAATGCCTGGGCAAGTGGCCTGAAAGACCAT
+ACCATACAGGTTTATGGCCCGCCGGGAACCCAGGCGATGACGAAGGCTAGCTGGAAGGTC
+TTTGACAGGGATATCACGTTACGCATGGAAGAAGAGGGGAAACCCGATCCGCGCAACCTG
+GTTAAGGCGACCGATATCGGCCAGGGCGTCATCTATAAAGATGAACTGGTCACAATAAGC
+GCGCTGAAAGTGCCTCATTCCCCTTTCCCGGACGGTGAAGCGTTTGCTTACCGTTTTGAT
+ACTCAGGGTAAGCGAATCGTCTTCTCTGGCGATACGTCCTGGTTTCCTCCGCTTGCAACG
+TTTGCCCAGGGGGCGGATATCCTGGTACATGAGGCGGTACATGTCCCTTCGGTAGCAAAA
+CTGGCTAATAGTATTGGCAACGGAAAAACGCTGGCTGAAGCGATTGCGTCGCATCACACC
+ACGATTGAAGATGTCGGTAAGATTGCTCGCGAGGCCCACGTGAAAAAACTGGTGTTAAGT
+CATCTGGTGCCTGCGACGGTTGCGGATGACGTCTGGCAACAGGAAGCCATGAAAAATTAC
+CCGGGCCCTGTCATTGTCGGTCATGACAATATGACGATAAGCGTACCGTAAATGTCGCAA
+CGCACAGAGAAAAAAATCGGGAAACGTTCGCAGGCCACCGGTGCAAAACGGCAGCTTATC
+TTAACCGCCGCGCTTGCCGTTTTTTCCCAGTATGGCATTCATGGCGCGCGTCTTGAACAG
+GTCGCCGAGCGGGCAGGCGTCTCCAAAACCAATCTGCTTTATTATTATCCCTCGAAAGAG
+GCGCTGTATGTCGCGGTAATGCGACAGATTCTGGATGTCTGGTTGGCGCCGCTCAAGGCG
+TTTCGCGCAGAATTTTCCCCTCTGGAGGCCATCAAAGAGTATATCCGTCTCAAGCTGGAG
+GTTTCGCGTGATTATCCGCAGGCGTCGCGGCTCTTCTGCATGGAGATGCTGGCGGGCGCG
+CCGCTCTTAATGGATGAACTGACCGGCGATCTAAAAGCGTTGATAGATGAAAAATCCGCG
+CTGATTGCCGGATGGGTGCACAGCGGGAAACTCGCGCCCGTTTCTCCGCATCATTTGATC
+TTCATGATTTGGGCCGCCACGCAACATTACGCCGATTTCGCCCCTCAGGTTGAAGCGGTA
+ACCGGCGCGACGCTTCGCGATGAAGCCTTTTTCAACCAAACGGTCGAAAGCGTTCAGCGC
+ATTATTATTGAAGGGATTCGCGTGCGTTAAATGGCGAAACAACAACGGATGGGCTGGTGG
+TTTCTTTGCCTTGCATGTGTCGTGGTAATGGTTTGTACCGCGCAACGCATGGCGGGCCTG
+CACGCCTTGCAGATGCAGGCGACGGCCTCTGCTGCGGTGGTCAGCGCTCCCTCCTCGACA
+GATGACGGCTCGCCGGTCACTCCCTGCGAATTAAGCGCCAAGTCGCTGCTGGCGGCGCCT
+CCAGTACTCTTTGAAGGTGCTATCCTTGCGCTTTATCTACTGCTTTCCTTACTGGCGCCT
+GTCCGGGTCATGCGCCTGCCGTTTTCGCCTCCACGGGCTATTTCGCCGCCCACATTACGG
+GTACATCTACGATTTTGTGTCTTCCGTGAATGAATGATGATTTTATTCAGGCGGATACTG
+TTCTGCCTGTTATGGCTTTGGCTGCCCGTCTCCTGGGCGGCGGAAAGCGGCTGGCTGCGT
+TCGCCCGATAACGACCATGCCAGCATACGGCTACGTGCCGATACGTCCGCTAACAGTGAG
+ACCCGGCTGTTGCTGGATGTCAAACTGGAAAACGGCTGGAAAACCTACTGGCGCGCGCCG
+GGGGAAGGGGGCGTGGCACCCTCTATCGCCTGGAAAGGCGACATGCCTGAGGTAAGCTGG
+TTCTGGCCAACCCCCTCGCGCTTTGATGTGGCGAATATCACCACCCAGGGATATCACGAC
+GAGGTGACCTTTCCGATGATCGTGCGCGGTACGCCGCCGGCGACCTTGCGCGGTGTGTTG
+ACGTTATCAACCTGCAGCAATGTTTGTCTGTTGACCGATTACCCCTTTTCCGTGACGCCC
+ACTGTGCAGAATGCCGATTTTGCCCATGACTATGCGCGGGCGATGGGTAAAGTTCCGCTC
+CGCAGTGGGCTAACGGACTCGCTTGACGTTGGCTATCGCCCGGGAGAACTGGTGGTCACT
+GCTACGCGAGCGGCGGGCTGGTCATCGCCCGGGCTCTATCTTGACACCATAGATGACGTC
+GATTTTGCGAAGCCTCGCCTGCGCGTAGAGGGCGACAGGTTACAGGCGACGGTGCCGGTG
+ACGGACAGTTGGGGCGAAAAGGCGCCCGATTTGCGCGACAAATCGCTGACCCTCGTGTTA
+GCCGATGGCGCTATCGCCCAGGAGAGCACGCAAACCATTGGCGCTGCGCCAGCGCAAACG
+CCGGACAATGCGGCGCTACCTTTCTGGCAAGTTGTAATGATGGCGCTAATCGGCGGACTG
+ATTCTTAATTTAATGCCCTGCGTACTGCCTGTTCTGGGCATGAAACTTGGCTCTATTTTA
+TTGGTAGAGGAAAAAAGCCGCTCTCACATCAGGCGACAATTTTTGGCTTCGGTCGCCGGT
+ATCATTGCGTCATTTATGGCGCTGGCGGCGTTTATGACCCTCCTTCGCCTGTCAAACCAT
+GCGCTGGCCTGGGGAGTCCAGTTCCAGAATGCATGGTTTATTGGTTTTATGGCGCTGGTG
+ATGTTGTTGTTTAGCGCCAGCCTGTTCGGGCTTTTTGAGTTCAGGCTTCCCTCATCTATG
+ACCACGAAACTGGCCACTTACGGCGGTAACGGTATGTCGGGACATTTCTGGCAGGGGGCG
+TTCGCCACGCTGCTGGCGACGCCTTGTAGCGCGCCGTTTCTGGGCACGGCGGTCGCGGTG
+GCGCTCACGGCGTCGCTGCCGACGCTGTGGGGGCTGTTCCTTGCGCTTGGCCTGGGAATG
+AGCGCGCCGTGGCTACTGGTCGCGATACGACCAGGGCTTGCGCTACGTTTACCGCGCCCC
+GGGCGTTGGATGAATGTCCTGCGCAGGATCCTCGGTCTGATGATGCTGGGGTCGGCTATC
+TGGCTGGCGACGTTACTCCTGCCGCATTTCGGCTTCACTGCGTCAAAGAGCGCGCAAGAC
+ACGGTTCAGTGGCAACCGTTGAGTGAACAGGCAATCCAGTCGGCGCTGGCGCAGCATAAG
+CGGGTATTTGTCGATGTCACTGCGGACTGGTGTATTACCTGTAAAGTGAATAAATACAAC
+GTCCTGCAAAAAGAGGATGTGCAGGCCGCCTTGCAACAGCCGGATGTTGTGGCGCTGCGG
+GGAGACTGGACGCTGCCGTCCGATGCCATTACAGATTTTCTGAAAACGCGCGGCCAGGTC
+GCCGTGCCGTTTAATCAGGTATATGGCCCCGGTTTGCCGGAAGGGGAGGCACTGCCCACT
+TTGCTGACCCGCGATGCGGTATTACAAACGTTGAAAAAAGCGAAAGGAATAACCCAATGA
+ATGAAATACATGATTGTTTTACTGCTGGCGCTGTTTTCGACGCTGAGCATCGCGCAAGAA
+ACCGCTCCTTTTACGCCGGATCAGGAAAAGCAGATTAAAAATCTGATCCATGCGGCGTTG
+TTTAACGATCCTGCCAGCCCGCGGATAGGCGCTAAACACCCTAAGCTGACGCTGGTGAAC
+TTTACGGATTACAACTGCCCGTACTGCAAACAGCTCGATCCGATGCTGGAAAAGATTGTG
+CAGAAATATCCTGACGTTGCGGTCATTATTAAACCGCTGCCATTCAAAGGAGAGAGTTCC
+ATACTGGCGGCGCGTATTGCGCTGACCACCTGGCGCGATCATCCGCAACAGTTCCTCGCG
+CTACATGAAAAACTTATGCAAAAGCGCGGTTACCATACGGATGACAGTATTAAACAGGCC
+CAGCAGAAAGCAGGGGCGACGCCAGTGACGCTGGATGAAAAAAGCATGGAAACGATACGC
+ACTAATTTGCAGTTGGCAAGACTGGTCGACGTGCAAGGAACGCCAGCGACGATCATTGGC
+GACGAGCTGATTCCGGGCGCAGTGCCCTGGGATACGCTGGAAGCGGTGGTGAAAGAAAAA
+CTGGCGGCTGCCAATGGCGGGTAAATGATTGCACATTCTTTCGGCATCGTTAATTATTTT
+GTATTATTTGGCTACCTCCTGGCCATGATGGTAGTCGGTGTCTATTTTTCCAGACGGCAA
+AAAACAGCAGACGATTATTTTCGCGGTGGTGGCCGGGTTCCTGGTTGGGCGGCTGGGGTC
+AGTGTATTTGCTACTACGTTAAGCTCAATTGCATTTATGTCAATTCCTGCCAAAGCGTTT
+ACTTCCGACTGGACGTTTATCATTGGTCAGGATCTGGCTATCGCAATTTTACCGCTGGTT
+TTTTATTTCTATATTCCGTTTTTTCGGAAAGTGAAAGTCACATCAGCCTATGAATATCTC
+GAAGCACGGTTCGATGTGCGCTGCCGTCTGGTCGCCAGCATGTCATTTATGTTGTTTCAT
+ATTGGACGTATCGCCATTATCACTTTCCTCGCCGTGCTGGCCTTGCGCCCCTTCATCGCT
+ATAGACCCGGTGATTTTGGTACTGTTGATTGGTGTGATGTGTATCATTTATACCTGGATG
+GGGGGGAATATGGAAAGTCTATTAAATCGTTTATATGACGCGTTAGGCCTGGATGCGCCA
+GAAGTTGAGCCACTGCTTATCATTGATGATGGGATACAGGTTTATTTTAATGAATCCGAT
+CATATACTGGAAATGTGCTGTCCCTTTATGCCACTGCCTGACGACACTCTGACTTTGCAG
+CATTTTTTACGTCTTAACTACGCCAGCGCCGTCACTATCGGCGCTGATGCAGACAATACT
+GCTTTAGTGGCGCTTTATCGCTTGCCGCAAACCAGTACCGAAGAAGAGGCGCTCACTGGT
+TTTGTATTATTCATTTCAAACGTGAAGCAATTGAAAGAGCATTATGCAATGAAATACGAC
+CTTATTATTATCGGCAGCGGTTCGGTTGGCGCCGCCGCTGGTTATTACGCCACCCGCGCC
+GGGCTAAAGGTCCTGATGACCGATGCGCATATGCCGCCTTATCAACAGGGCAGCCACCAC
+GGCGATACCCGTCTTATCCGCCACGCTTATGGTGAAGGCGAAAAATATGTCCCGCTGGTG
+CTTCGCGCCCAGACGCTTTGGGATGAGCTCTCCACACACAATGAAGAGCCTATTTTTGTC
+CGCTCCGGCGTCGTCAACCTCGGCCCGGCCGATTCCGCTTTCTTAGCCAACGTCGCACGA
+AGCGCGCAACAGTGGCAATTGAACGTCGAGCGCCTGGACGCGACGGCCCTCATGACGCGC
+TGGCCGGAAATTCGCGTGCCCGATAATTATATCGGGCTGTTTGAAGCTGACTCCGGTTTC
+CTGCGCAGCGAATTAGCCATTACCACATGGCTTCGTCTGGCCCGAGAGGCAGGCTGCGCA
+CAGCTATTCAACAGCCCGGTAAGCCATATTCACCATGATGATAACGGTGTGACGATAGAG
+ACGAGTGAAGGCTGCTACCACGCCAGCAAAGCGCTGATTAGCGCGGGCACCTGGGTCAAA
+ACGCTGGTACCGGAGCTGCCCGTTCAGCCCGTACGTAAAGTTTTTGCCTGGTTTAAGGCG
+GATGGACGTTACAGCACTAAAAACCGCTTTCCGGCCTTTACCGGCGAAATGCCCAACGGC
+GATCACTATTACGGTTTCCCGGCGGAGAACGACGAGTTAAAAATCGGCAAACACAATGGC
+GGGCAGCGAATACAGGCACCGGAAGAGCGCAAGCCCTTTGCCGCCGTTGCCAGCGATGGC
+GCGGAAGCATTTCCTTTCCTGCGTAACGTACTGCCGGGTATCGGCGGTTGTTTACATGGG
+GCGGCATGTACCTATGATAATTCGCCGGACGAGGATTTTATTATCGATACGCTGCCTGGC
+CATGAGAATACGCTTGTCATCACTGGACTCAGCGGACATGGTTTTAAATTCGCCCCGGTG
+TTAGGAGAAATCGCTGCGGATTTTGCGTTGGGAAAAACGCCCTCCTTTGATCTGACGCCG
+TTCCGGCTTTCCCGTTTTAGCCAATAAATGCAAATACAGAGCTTCTATCACTCAGCTTCA
+CTAAAAACCCAGGAGGCTTTTAAAAGCCTACAAAAAACCTTATACAACGGAATGCAGATT
+CTCTCAGGCCAGGGCAAAGCGCCGGCTAAAGCGCCCGACGCTCGCCCGGAAATTATTGTC
+CTGCGAGAACCTGGCGCGACATGGGGGAATTATCTACAGCATCAGAAGACGTCTAACCAC
+TCGCTGCATAACCTCTATAACTTACAGCGCGATCTTCTTACCGTCGCGGCAACCGTTCTG
+GGTAAACAAGACCCGGTTCTAACGTCAATGGCAAACCAAATGGAGTTAGCCAAAGTTAAA
+GCGGACCGGCCAGCAACAAAACAAGAAGAAGCTGCGGCAAAAGCATTGAAGAAAAATCTT
+ATCGAACTTATTGCAGCACGCACTCAGCAGCAAAATGGCTTACCTGCAAAAGAAGCTCAT
+CGCTTTGCGGCAGTAGCGTTTAGAGATGCTCAGGTCAAGCAGCTCAATAACCAGCCCTGG
+CAAACCATAAAAAATACACTCACGCATAACGGGCATCACTATACCAACACGCAGCTCCCT
+GCCGCAGAGATGAAAATCGGCGCAAAAGATATCTTTCCCAGTGCTTATGAGGGAAAGGGC
+GTATGCAGTTGGGATACCAAGAATATTCATCACGCCAATAATTTGTGGATGTCCACGGTG
+AGTGTGCATGAGGACGGTAAAGATAAAACGCTTTTTTGCGGGATACGTCATGGTGTGCTT
+TCCCCCTATCATGAAAAAGATCCGCTTCTGCGTCAGGCCGGCGCTGAAAACAAAGCCAAA
+GAAGTATTAGCTGCGGCACTTTTTAGTAAACCTGAGTTGCTTAACAGAGCCTTAGAGGGC
+GAAGCGGTAAGCCTGAAACTGGTATCCGTCGGGTTACTCACCGCGTCGAATATTTTCGGC
+AAAGAGGGAACTATGGTCGAGGATCAAATGCGCGCATGGCAATCGTTGACCCAGCCGGGA
+AAAATGATTCATTTAAAAATCCGCAATAAAGATGGCGATCTACAGACGGTAAAAATAAAA
+CCGGACGTCGCCGCATTTAATGTGGGTGTTAATGAGCTGGCGCTCAAGCTCGGCTTTGGC
+CTTAAAGCATCAGATAGCTATAATGCCGAAGCGCTACATCAGTTATTAGGCAATGATTTA
+CGCCCTGAAGCCAGACCAGGTGGCTGGGTTGGCGAATGGCTGGCGCAATACCCGGATAAT
+TATGAGGTCGTCAATACATTAGCGCGCCAGATTAAGGATATCTGGAAAAATAACCAACAT
+CATAAAGATGGCGGCGAACCCTATAAACTCGCACAACGCCTTGCCATGTTAGCCCATGAA
+ATTGACGCGGTGCCCGCCTGGAATTGTAAAAGCGGCAAAGATCGTACAGGGATGATGGAT
+TCAGAAATCAAGCGAGAGCTCATTTCTTTCCATCAGACCCATATGTTAAGTGCGCCTGGT
+AGTCTTCCGGATAGCGGTGGACAGAAAATTTTCCAAAAAGTATTACTGAATAGCGGTAAC
+CTGGAGATTCAGAAACAAAATACGGGCGGGGCGGGAAACAAAGTAATGAAAAATTTATCG
+CCAGAGGTGCTCAATCTTTCCTATCAAAAACGAGTTGGGGATGATAATATTTGGCAGTCA
+GTAAAAGGTATTTCTTCATTAATCACATCTATGAAACGATATATACTGGCTACCGCGATA
+GCGTCTCTTGTTGCAGCCCCGGCAATGGCGCTGGCCGCTGGCAGCAATATTCTCAGCGTA
+CATATTCTCGATCAGCAAACAGGCAAACCAGCGCCCGGCGTGGAGGTGGTACTGGAGCAG
+AAAAAGGATAACGGATGGACGCAATTAAACACCGGGCATACCGACCAGGATGGACGAATT
+AAAGCACTGTGGCCCGAAAAAGCTGCCGCGCCGGGGGATTATCGCGTTATTTTTAAAACC
+GGCCAGTATTTTGAAAGTAAAAAACTGGACACGTTTTTCCCGGAGATTCCCGTCGAGTTT
+CATATCAGCAAAACGAATGAGCACTATCATGTGCCGCTGTTATTAAGTCAGTATGGTTAT
+TCAACCTATCGCGGGAGCTAAATGGCAAAGATTCTGGTGCTCTATTATTCCATGTACGGA
+CACATTGAAACCATGGCGCACGCGGTGGCGGAAGGGGCAAAGAAAGTCGACGGCGCAGAG
+GTCATTATAAAGCGTGTGCCAGAAACAATGCCGCCTGAAATCTTCGCAAAAGCTGGCGGT
+AAAACGCAAAACGCACCGGTTGCCACCCCACAGGAGCTGGCGGATTACGATGCCATTATT
+TTTGGTACGCCAACCCGGTTTGGCAATATGTCAGGCCAGATGCGTACCTTCCTGGACCAA
+ACCGGCGGACTGTGGGCATCCGGCGCGCTATACGGCAAGCTCGGCGGCGTGTTCAGTTCT
+ACCGGAACGGGCGGCGGCCAGGAGCAGACCATCACCTCGACCTGGACTACGCTTGCCCAT
+CATGGGATGGTGATTGTCCCGATAGGCTATTCCGCACAGGAACTGTTTGACGTCTCCCAG
+GTTCGCGGCGGTACGCCTTACGGCGCAACGACTATCGCTGGAGGCGACGGTTCACGTCAA
+CCAAGCCAGGAGGAACTCTCTATCGCTCGCTATCAGGGGGAATACGTCGCCGGTCTGGCA
+GTCAAACTCAACGGCTAAATGGAGCCTCAACCCCCACGTCTGAAACCCGGAAAAATCCTT
+GACACTCTGGGTGCTATGCAAAAAAGCCTGACACGTGCCTCGCAGCGTATTGCGCAATAT
+ATTTTAGCCTTCCCCAGACAGGTGACACAGTCATCTATTGCGGATTTGTCGCGCGACACA
+CAGGCCGGAGAAGCCACGGTTATTCGCTTTTGTCGCACCCTGGGCTATAAAGGTTTTCAG
+GATTTTAAAATGGACCTGGCCATTGAACTTGCCACTACCGAGTCTGATGACAGTAGTCCT
+CTACTGGATGCCGAAGTTAGCGAATCCGACGATGCCCACGCGATTGGTTTAAAATTGCAG
+AACACCATTAGTAATGTATTATCTGAAACGCTAAATCTGCTGGATATGCAACAGGTTCTC
+GGTGTCGTGGACGCCCTACGTCACTGTCACTCAGTTTATATGTTTGGTGTGGGCTCATCG
+GGGATCACGGCGCTGGATATGAAACACAAGCTAATGCGTATGGGTTTACGGGGCGATGCG
+GTAAGCAATAACCATTTTATGTACATGCAGGCTACGCTATTGAAAGCAGGCGATGTCGCG
+ATGGGTGTCAGTCACTCGGGCACATCGCCAGAAACAGTGCATTCACTCCGATTGGCCCGA
+CAGGCTGGCGCCACCACAGTCGCCATTACCCATAATCTGGGTTCTCCATTATGTGAAGAG
+GCCGATTTTTGCCTGATCAATGGTAATCGGCAAGGAATGTTGCAGGGTGACTCGATCGGT
+ACGAAAGCCGCGCAGCTTTTCGTCTTTGACCTGCTCTATACCCTTCTTGTACAGTCCTCG
+CCGGAACAGGCCCGAGAAAGCAAATTACGGACAATGAATGCCCTGGACATGACAAAAATG
+AAGAAACTGCCCGGCTTTACGCAAGATTACTTACTCAGCAAGGCGACGACCCTGCCTGAT
+AAAACACGCCTGGAGCGTGCCGTTGAACCGCTATGCGCGCGCCATCCCGGAGAGTGCGGC
+ATTCTTGCGCTGGATAACAGTCTGGACGCTTTTGCCGCCCGCTACCGCCTGACCGAAATG
+GCGGCGCGGACGCTGGATGTGCAGTATTATATTTGGGAAGACGATATGTCCGGGCGGCTG
+CTCTTTTCGGTTCTGCTGTCGGCGGCGAAGCGCGGCGTTCATGTTCGTCTGCTGCTGGAT
+GATAACAATACGCCTGGTCTGGATGATACGTTGCGCTTGCTGGATAGCCATCCTAATATC
+GAAGTTCGTCTGTTTAATCCTTTCTCTTTTCGTACGCTACGCGCGCTGGGATATTTGACG
+GATTTTGCGCGGCTGAATCGGCGGATGCACAATAAAAGTTACACTGCCGACGGCGTAGTG
+ACGCTGGTCGGTGGGCGCAACATCGGCGATGCCTATTTCGGCGCTGGCGAGGAGCCGCTA
+TTTTCCGATCTGGACGTGATGGCCATTGGCCCGGTGGTCAATGATGTCGCCAATGATTTT
+GAACGTTACTGGCGCTGTAGTTCAGTGTCGACATTGCAGCAAGTATTATCCCTTTCTGAG
+CAGGAACTGACGCAGCGTATCGAACTTCCCGAATCCTGGTATAACGATGAGATCACCCGC
+CGTTATCTGCATAAGCTGGAAACCAGCCAGTTTATGGCGGATCTCGATCGCGGAACGTTG
+CCGCTGATTTGGGCAAAAACACGCTTGCTTAGCGATGACCCTTCTAAAGGCGAGGGGAAG
+GCGCAGCGCCATTCGCTTCTTCCGCAGCGATTATTTGACGTGATGGGGTCGCCGACGGAG
+CGTATCGACATTATTTCCGCTTACTTTGTCCCTACGCGCGCAGGCGTGGCGCAGTTGCTT
+AATCTGGTCAGGAAAGGTGTGAAGATCGCCATCTTAACTAACTCTCTGGCGGCCAACGAT
+GTGGCGGTCGTTCACGCAGGGTACGCGCGCTGGCGCAAGAAATTACTGCGCTATGGCGTG
+GAGCTCTACGAACTGAAACCGACCCGCGAACATGAAACCGCCGTACATGATCGCGGACTC
+ACCGGGAACTCAGGTTCCAGCTTACATGCTAAAACGTTCAGTATTGATGGTAGTAAGGTG
+TTTATCGGGTCGCTTAATTTTGATCCCCGTTCAACGCTTTTAAATACCGAAATGGGCTTT
+GTCATTGAAAGTGAAACGCTGGCGACGCTTATTCATAAGCGTTTTACGCAGAGCCAACGC
+GATGCGGCCTGGCAACTGCGGCTGGATCGCTGGGGACGAATTAACTGGATCGATCGTCAG
+CAAGAAGAGGAAAAGGTGTTAAAGAAAGAACCCGCTACGCGTTTCTGGCAGCGAGTTCTG
+GTACGGTTGGCGGCAATTTTACCTGTGGAATGGTTGCTGTGAATGCCAACTCAAGAAGCA
+AAAGCGCACCGCGTCGGCGAATGGGCAAGCCTGCGTAATACGTCGCCGGAAATTGCCGAA
+GCCATTTTTGAAGTCGCTCACTATGACGAGAAACTGGCAGAAAAAATATGGGAAGAAGGT
+AGCGATGAGGTGCTGATCAAAGCCTTTGAGAAAACGGACAAAGACTCGCTCTTCTGGGGC
+GAACAAGTCATCGAACGTAAGAACGTATAAATGTATCCCGTTGACCTGCATATGCATACC
+GTCGCGAGCACTCATGCCTACAGTACTCTGAGCGATTATATCGCGGAAGCCAAACGCAAA
+GGCATGAAACTTTTTGCGATTACCGATCATGGTCCGGACATGGAAGATGCGCCGCATCAC
+TGGCAGTTTATTAACATGCGCATCTGGCCGCGTCTGGTTGACGGCGTGGGGATACTGCGT
+GGCATGGAGGCGAATATCAAGAATATTAACGGTGAAATTGATTGTTCCGGAAAGATGTTC
+GACTCGCTGGATCTGATTATCGCAGGCTTTCATGAGCCCGTTTTTGCGCCGCATGATAAA
+GAAACGAATACTCAGGCGATGATCGCGACCATCGCCAGCGGCAAGGTGCATATAATTAGT
+CACCCGGGAAATCCAAAGTATCCAGTGGAGGTTAAAGCCATCGCGCAGGCGGCGGCGAAA
+CACCAGGTAGCGCTGGAAATCAACAACTCTTCTTTTCTGCATTCGCGTAAAGGAAGCGAA
+GATAAGTGCCGCGCGGTCGCTGCCGCCGTACGCGATGCGGGAGGCTGGGTAGCGTTAGGC
+TCTGAGTCCCATACGGCCTTTACGCTTGGCGATTTCACCGAATGCCGGAAAATTCTGGAT
+GCGGTGAATTTTCCGGAAGATCGAATCCTGAACGTCTCTCCGCAGCGCTTACTGGCCTTT
+CTCGAGTCACGCGGTATGGCGCCTGTACCGGAATTTGCCGAACTTATGAATGAGTTTTCA
+ATCCTGTGCCGTGTGCTGGGATCGTTGTTTTACCGCCAAGCGCAAGATCCTTTACTGGTT
+CCGCTGTTTACGTTAATCCGTGAAGGTAAACTGGCGGCAGACTGGCCGCTGGAGCAGGAT
+GACATGCTGGCGCGTTTACAGAAAAGCTGCGATATCACGGAGATTTCCACTGATTACAAT
+GCGTTATTTGTTGGGGAAGAGTGCGCGGTAGCGCCATACGGCAGTGCGTGGGTCGAAGGC
+GCGGAAGAGTCTGAGGTGCGCGCTTTTTTAACGTCGCGAGGGATGCCGCTGGCCGATACG
+CCTGCCGATCACATTGGCACTTTATTGCTCGCGGCCTCCGGGCTGGAAGATCAGTCTGCC
+GAAGATGAAAGTGAAGCGCTGGAAACCTTATTTGCCGATGATCTGCTTCCCTGGTGCAAT
+ACCTTCCTCGGTAAAGTTGAAGCCCATGCCGTTACGCCAGTCTGGCGCACTCTGGCGCCG
+CTAACGCGTGATGCGATAGGGGCCATGTGGGATGAACTTGAGGAAGAAGATGAAGAAATG
+ATGCGCGCGATGAACATACTTCTTTCTATTGCTATCACTACGGGCATCCTTTCTGGAATA
+TGGGGATGGGTGGCCGTCTCCCTGGGGTTACTAAGCTGGGCCGGTTTTTTAGGCTGTACG
+GCTTATTTGGCCTGTCCGCAGGGCGGCTTTAAGGGATTGTTGATTTCCGCCTGTACGCTG
+TTAAGCGGGATGGTGTGGGCGCTGGTCATTATTCACGGTAGCGCGTTGGCGCCGCATCTG
+GAAATTGTGAGTTACGTGTTGACGGGGATCGTGGCATTCCTGATGTGTATCCAGGCAAAG
+CAGCTATTGCTTTCTTTTGTTCCGGGAACATTTATCGGCGCCTGCGCGACATTTGCAGGG
+CAGGGTGAGTGGCGGTTGGTATTACCGTCGCTGGCGCTGGGGCTAATCTTTGGCTATGCC
+ATGAAAAAGAGTGGGCTATGGCTGGCATCACGCCGCGAGCAACATTCAGCGAATACGGCG
+GTCACAAAGATGAAAAAAAACCTGCTGGGATTCACCCTCGCATCCTTGTTATTCACGACC
+GGTTCCGCCGTGGCGGCGGAGTATAAAATTGATAAAGAAGGCCAACATGCGTTCGTCAAT
+TTCCGCATCCAGCATCTGGGCTACAGCTGGCTATACGGCACCTTTAAAGATTTCGACGGC
+ACGTTCACTTTTGACGAAAAAAATCCGTCAGCAGACAAAGTGAATGTGACCATTAACACC
+AATAGCGTCGACACTAACCATGCCGAACGTGACAAACACCTGCGTAGCGCGGAGTTTCTT
+AATGTTGCGAAATTCCCGCAGGCAACCTTCACCTCTACCAGCGTGAAAAAAGAGGGCGAT
+GAACTGGATATTACCGGCAATCTGACGCTCAATGGCGTGACTAAACCGGTGACGCTGGAA
+GCGAAGCTGATGGGCCAGGGCGACGATCCGTGGGGCGGTAAGCGCGCGGGCTTTGAGGCC
+GAAGGAAAAATTAAGCTGAAAGATTTCAATATAACTACCGATCTCGGCCCAGCCTCACAA
+GAGGTGGAGCTTATCATCTCAGTAGAAGGCGTTCAGCAGAAGTAAATGTTACTGATGATG
+GCGCTGATCGTGCGTATTATCTGGCGGCTTTATTCTCCGCCGCCCGTTGCGTTGACCAGC
+TATTCCCGTTTAACGCGCATTGGCGCCGCCGCGGGTCATATCCTTCTGTATCTCCTGCTC
+TTTGCGATAATCATTAGCGGCTACCTGATTTCCACCGCCGACGGTAAACCGATTAGCGTC
+TTTGGCTGGTTTGAGATTCCGGCCACGCTTACGGACGCGGGCGCGCAGGCTGACATCGCC
+GGAACACTGCATCTGTGGTTTGCCTGGTCGCTGGTCATTATCTCGCTCTCGCATGGGGTT
+ATGGCGCTAAAACACCATTTCATCGATAAAGACGACACACTGAAACGTATGACAGGAATG
+TCGTCATCTGACTATGGAGCTCAAAAATGAATGGTTAAGTTATCAATGACGCTGCGCCTG
+ACAATTTCTTTTATCGCCATACTTATCCTCGCCTGTACCGGCATTAGCTGGACGCTCTAT
+AACGCGCTGAGCAAAGAATTAACGTATCGGGATGATATGACGCTAATAAATCGGGCGGCG
+CAAATGCAGCAACTGTTACTGGATGGCGCCAGGCCGGAAAATCTGCCGCTCTATTTCAAT
+CGGATGGTGGATACGAAGCAGGATATCTTATTGATCCACTCAGCAACAGGCCATAATGTT
+GCGATTAATCATAGCGGCATCCCCGACCAACGCTTTAACGAGATTCCGCTGGCTAAAAAC
+ATCACCCGCGAAACCTTATTTCGCCAGGCGGTACAAGGCACGGAGCTGACCGCGGTACGA
+GTAAACGCCAGAAGCGGCGATAACCCGCTGACCCTTACTATTGCCAGGCTGGCGACGGAA
+AGGCGGCAAATGCTGGCGCAATATCGCCGCAACAGTTTGCTGATTAGCCTTATCGCGATC
+CTCGTCTGTTCGGCGCTCAGTCCATTAGTCATCAGAAACGGGCTGCGGGCCATTACGTCG
+CTCAGCCGACTCACCGCGGCGACAGATAGCGGCACACTTCGCCAGCCGCTGGCGGAACAG
+GCGTTACCCGTCGAGCTCAGGCCGCTTGGGCAAGCGCTAAATACCATGCGCCAGAAGCTT
+TCCGACGATTTTGAACGCCTGAACCAATTTGCCGACGATCTGGCGCATGAGCTGCGCACG
+CCGGTTAATATTTTACTGGGGAAGAATCAGGTTATGCTGAGTCAGGAACGCAGCGCCGAA
+GAGTATCAACAAGCCCTTGTCGATAATATTGAAGAGCTGGAGGGACTGTCGCGACTGACA
+GAAAATATTCTCTTTCTGGCACGCGCGGAGCACCAGAATATAGCGGTAAAAAAACAGCCT
+GTTTCGCTCAATGCGCTGGTCGAAAATATGCTGGATTATCTTAGCCCCCTTGCCGAAGAG
+AAGCACATCTGTTTTATAAATCAATGTCAGGGAACGGTATGGGCTGACGAAATATTATTA
+CAAAGAGTGCTCTCAAACCTGCTGACGAATGCCATCCGTTATTCTGATGAAAACGCCGTG
+ATACGTATTGAAAGCGCTTATGATGATAACGTTGCAGAAATTCGGGTCGCTAATCCGGGC
+AGCCCCACCGCCGATGCGGATAAGCTTTTCCGGCGTTTTTGGCGAGGAGATAATGCCCGC
+TACACTGCCGGTTTCGGCCTGGGGTTATCGTTAGTTAACGCGATTGCCCTATTGCACGGT
+GGCTCGGCATCTTACCGCTATGCCGATGAACATAATATCTTTTCGGTTCGTCTGCCTGAT
+AGCGGTGATAGCTAAGTGATATGTCTGAAAGTCCAGGGCGGCATTGGTGAAATTTTTACG
+GTGACGCAGCAGGCGGATAAATTCTTGCCGGCTACGCAGTTCCACTGGAGCTGGACGGAA
+AGCACAGTACCTGTATTGATGATTGGGTTTCTGTTTGCCAATATTCAGCAATTTACTGCC
+AGTCAGGATGTGGTCCAACGCTATATGGTGACTGACTCCATAGAGGAAACGAAGAAAACA
+TTACTTACAAATGCCAAACTGGTTGCGGTGATCCCTGTTTTCTTTTTTGCTATCGGCTCG
+GCATTATTTGTCTACTATCAGCAACAGCCACAATTATTACCGGCGGGATTCAACACTGGC
+GGCATTTTGCCCTTATTCGTGGTCACGGAAATGCCAGTCGGCATTGCAGGGTTGATAATC
+TCCGCTATTTTCGCTGCCGCGCAGTCGAGCATCTCCAGCAGCTTAAACAGCATTTCCAGT
+TGTTTTAATTCCGATATCTATCAGCGGTTGAGTCATAAAAAAGGAACGCCAGAAAACCGT
+ATGAAAATAGCTAAGTTAGTTATTCTGGTCGCGGGCCTGATAAGTAGCGCGGCCTCGGTA
+TGGCTGGTCATGGCCGATGAATCAGAGATCTGGGATGCATTTAATAGTCTGATAGGTCTG
+ATGGGAGGGCCAATGACCGGTCTGTTGATGCTGGGCATTTTCTTTAAACGAGCAAATGCC
+GGGAGTGCGGTTTTAGGAATTATTATGAGCGTCATTACCGTGCTGGGCACACGCTATGCC
+ACTGACCTTAACTTCTTCTTTTATGGGGTCATTGGCTCGCTAAGCGTGGTGATCAGCGGC
+GTTATTTTCGCCCCGTTATTTGCCCCGGCACCGCCATTGACGCTGGATGAAAAACCTGAA
+CCAAAGGTGACATTAATGAAAATCAACAGATATCTTCTGGGTATGGTTTCGTTTATAGCA
+TTTTCATCATATCTACAAGCGGCAACCCTTGATTATCGGCATGAATATGCTGATAGAACC
+AGAATTAATAAAGACCGTATTGCTATAATTGAAAAGCTTCCTAACGGCATTGGTTTTTAT
+GTCGATGCCAGCGTTAAATCGGGAGGAGTAGATGGTGAGCAGGATAAGCATTTAAGCGAT
+CTCGTCGCAAACGCTATAGAACTGGGCGTAAGTTATAATTATAAAGTTACGGACCATTTT
+GTTTTGCAGCCTGGATTTATATTTGAAAGCGGTCCAGACACTTCAATTTATAAGCCTTAT
+TTAAGGGCGCAATATAATTTTGATTCTGGTGTTTATATGGCTGGTCGTTACCGTTATGAC
+TATGCAAGGAAGACAGCTAACTATAATGATGATGAGAAAACGAATAGATTTGATACTTAT
+ATAGGTTATGTTTTTGATGAGTTGAAATTGGAATATAAATTTACCTGGATGGATAGCGAT
+CAAATTAAATTTGATAACAAAAAAACAAACTATGAACATAATGTGGCTTTAGCCTGGAAA
+CTGAATAAGTCATTTACACCATACGTTGAGGTCGGAAATGTAGCGGTGAGAAATAATACC
+GATGAGAGACAGACCCGTTATCGCGTTGGATTACAATACCACTTTTGAATGACGAAATAC
+GGTGTTATAGGTACAGGTTATTTTGGCGCTGAACTGGCGCGATTTATGTCTAAGGTTGAA
+GGGGCGAAAATCACTGCGATTTACGATCCGGTAAATGCGGCTCCGATAGCGAAAGAGCTG
+AACTGTGTCGCCACTTCAACGATGGAGGCGCTTTGTACCCATCCTGATGTGGATTGCGTA
+ATTATTGCTTCACCAAATTACTTACATAAAGCGCCGGTCATTGCGGCGGCTAAAGCGGGT
+AAACACGTGTTTTGTGAAAAACCTATCGCCTTAAATTACCAGGATTGTAAGGATATGGTT
+GATGCCTGCAAAGAAGCTGGTGTTACCTTTATGGCGGGTCACGTTATGAACTTTTTTCAC
+GGGGTTCGCCACGCTAAAGCGCTCATCAAAGCCGGTGAAATCGGTGAAGTTACACAAGTT
+CACACTAAACGTAATGGTTTTGAAGACGTGCAGGATGAGATCTCATGGAAGAAGATTCGC
+GCAAAGTCAGGTGGGCATCTGTACCATCACATTCACGAGCTAGATTGTACACTGTTCATC
+ATGGATGAAACCCCATCCCTGGTTTCAATGGCGGCGGGGAATGTTGCGCACAAAGGTGAA
+AAATTTGGTGATGAAGATGATGTTGTCCTAATCACCCTTGAGTTTGAAAGCGGTCGTTTC
+GCGACACTTCAGTGGGGATCATCGTTCCACTACCCTGAGCACTATGTATTAATTGAGGGC
+ACGACAGGTGCAATTCTCATTGATATGCAAAACACGGCTGGTTATCTAATAAAAGCGGGC
+AAAAAAACACACTTTCTTGTGCATGAAAGCCAGGCGGAGGATGATGATCGTCGCAACGGT
+AACATATCCAGCGAGATGGATGGCGCAATCGCTTATGGTAAACCCGGTAAACGTACGCCG
+ATGTGGCTCTCATCAATTATGAAACTGGAGATGCAGTACTTGCATGATGTGATAAACGGT
+CTGGAGCCAGGCGAGGAGTTTGCTAAATTGCTAACGGGAGAAGCGGCGACAAATGCCATT
+GCTACCGCTGATGCTGCGACGCTTTCTTCAAACGAGGGGCGCAAAGTTAAACTCACTGAA
+ATTCTTGGCTAAATGACATCACGTCTTCAGGTCATACAGGGTGATATCACTCAACTTAGC
+GTCGATGCGATTGTGAATGCCGCTAACGCATCATTAATGGGCGGCGGTGGCGTAGACGGC
+GCAATTCATCGCGCGGCGGGGCCGGCATTGCTGGACGCCTGTAAACTCATCCGTCAGCAA
+CAGGGCGAATGTCAGACGGGACATGCGGTTATCACGCCTGCTGGCAAGCTTTCGGCAAAG
+GCGGTTATTCACACAGTGGGGCCCGTCTGGCGAGGCGGCGAACACCAGGAAGCTGAGCTA
+CTCGAAGAGGCATACCGGAATTGTTTGCTGCTTGCCGAGGCGAATCACTTTCGTTCCATC
+GCTTTTCCGGCAATCAGTACCGGCGTTTATGGCTATCCACGCGCCCAGGCCGCTGAAGTC
+GCCGTCAGGACGGTTTCAGATTTTATTACCCGTTACGCTCTGCCTGAACAGGTATACTTT
+GTCTGTTATGATGAAGAAACTGCCCGGCTTTACGCAAGATTACTTACTCAGCAAGGCGAC
+GACCCTGCCTGA
diff --git a/t/data/expected_reannotated_groups_file b/t/data/expected_reannotated_groups_file
new file mode 100644
index 0000000..aa08715
--- /dev/null
+++ b/t/data/expected_reannotated_groups_file
@@ -0,0 +1,7 @@
+hly: 1_1 2_1 3_1
+argF: 1_3 3_3
+group_4: 2_4 3_4
+speH: 1_2 2_2
+yfnB: 3_5
+group_7: 2_7
+group_6: 1_6
diff --git a/t/data/expected_sample_weights_accessory_graph.dot b/t/data/expected_sample_weights_accessory_graph.dot
new file mode 100644
index 0000000..d88fd4f
--- /dev/null
+++ b/t/data/expected_sample_weights_accessory_graph.dot
@@ -0,0 +1,15 @@
+digraph g
+{
+
+ /* list of nodes */
+ "group_X";
+ "group_X";
+ "group_X";
+ "group_X";
+ "group_X";
+
+ /* list of edges */
+ "group_X" -> "group_X" [weight = "2"];
+ "group_X" -> "group_X" [weight = "2"];
+ "group_X" -> "group_X" [weight = "2"];
+}
diff --git a/t/data/expected_sample_weights_core_accessory_graph.dot b/t/data/expected_sample_weights_core_accessory_graph.dot
new file mode 100644
index 0000000..6f187a6
--- /dev/null
+++ b/t/data/expected_sample_weights_core_accessory_graph.dot
@@ -0,0 +1,22 @@
+digraph g
+{
+
+ /* list of nodes */
+ "group_A";
+ "group_B";
+ "group_C";
+ "group_D";
+ "group_E";
+ "group_F";
+ "group_G";
+ "group_H";
+
+ /* list of edges */
+ "group_A" -> "group_B" [weight = "2"];
+ "group_C" -> "group_B" [weight = "2"];
+ "group_C" -> "group_D" [weight = "2"];
+ "group_E" -> "group_D" [weight = "0.625"];
+ "group_E" -> "group_F" [weight = "0.625"];
+ "group_F" -> "group_G" [weight = "2"];
+ "group_G" -> "group_H" [weight = "2"];
+}
diff --git a/t/data/expected_set_difference_common_set b/t/data/expected_set_difference_common_set
new file mode 100644
index 0000000..c38f7c4
--- /dev/null
+++ b/t/data/expected_set_difference_common_set
@@ -0,0 +1,3 @@
+group_1: 1_1 2_1 3_1
+group_3: 1_3 3_3
+group_2: 1_2 2_2
diff --git a/t/data/expected_set_difference_common_set_statistics.csv b/t/data/expected_set_difference_common_set_statistics.csv
new file mode 100644
index 0000000..bcf3868
--- /dev/null
+++ b/t/data/expected_set_difference_common_set_statistics.csv
@@ -0,0 +1,4 @@
+"Gene","Non-unique Gene name","Annotation","No. isolates","No. sequences","Avg sequences per isolate","Genome Fragment","Order within Fragment","Accessory Fragment","Accessory Order with Fragment","QC","Min group size nuc","Max group size nuc","Avg group size nuc","query_1.fa.tmp.filtered.fa","query_2.fa.tmp.filtered.fa","query_3.fa.tmp.filtered.fa"
+"group_1","","","3","3","1","","","","","","","","","1_1","2_1","3_1"
+"group_2","","","2","2","1","","","","","","","","","1_2","2_2",""
+"group_3","","","2","2","1","","","","","","","","","1_3","","3_3"
diff --git a/t/data/expected_set_difference_unique_set_one b/t/data/expected_set_difference_unique_set_one
new file mode 100644
index 0000000..d72c802
--- /dev/null
+++ b/t/data/expected_set_difference_unique_set_one
@@ -0,0 +1 @@
+group_6: 1_6
diff --git a/t/data/expected_set_difference_unique_set_one_statistics.csv b/t/data/expected_set_difference_unique_set_one_statistics.csv
new file mode 100644
index 0000000..9dbe73c
--- /dev/null
+++ b/t/data/expected_set_difference_unique_set_one_statistics.csv
@@ -0,0 +1,2 @@
+"Gene","Non-unique Gene name","Annotation","No. isolates","No. sequences","Avg sequences per isolate","Genome Fragment","Order within Fragment","Accessory Fragment","Accessory Order with Fragment","QC","Min group size nuc","Max group size nuc","Avg group size nuc","query_1.fa.tmp.filtered.fa","query_2.fa.tmp.filtered.fa","query_3.fa.tmp.filtered.fa"
+"group_6","","","1","1","1","","","","","","","","","1_6","",""
diff --git a/t/data/expected_set_difference_unique_set_two b/t/data/expected_set_difference_unique_set_two
new file mode 100644
index 0000000..9b9fe13
--- /dev/null
+++ b/t/data/expected_set_difference_unique_set_two
@@ -0,0 +1,3 @@
+group_4: 2_4 3_4
+group_7: 2_7
+group_5: 3_5
diff --git a/t/data/expected_set_difference_unique_set_two_statistics.csv b/t/data/expected_set_difference_unique_set_two_statistics.csv
new file mode 100644
index 0000000..3e0c956
--- /dev/null
+++ b/t/data/expected_set_difference_unique_set_two_statistics.csv
@@ -0,0 +1,4 @@
+"Gene","Non-unique Gene name","Annotation","No. isolates","No. sequences","Avg sequences per isolate","Genome Fragment","Order within Fragment","Accessory Fragment","Accessory Order with Fragment","QC","Min group size nuc","Max group size nuc","Avg group size nuc","query_1.fa.tmp.filtered.fa","query_2.fa.tmp.filtered.fa","query_3.fa.tmp.filtered.fa"
+"group_4","","","2","2","1","","","","","","","","","","2_4","3_4"
+"group_5","","","1","1","1","","","","","","","","","","","3_5"
+"group_7","","","1","1","1","","","","","","","","","","2_7",""
diff --git a/t/data/expected_some_different_output b/t/data/expected_some_different_output
new file mode 100644
index 0000000..b2fe49b
--- /dev/null
+++ b/t/data/expected_some_different_output
@@ -0,0 +1,95 @@
+csgE: 11111_1#11_04109 22222_2#22_04109
+flgJ: 11111_1#11_04150 22222_2#22_04150
+hpaA: 11111_1#11_04075 22222_2#22_04075
+sopB: 11111_1#11_04059 22222_2#22_04059
+csgG: 11111_1#11_04107 22222_2#22_04107
+hpcB: 11111_1#11_04070 22222_2#22_04070
+ycdZ: 11111_1#11_04106 22222_2#22_04106
+uraH: 11111_1#11_04063 22222_2#22_04063
+yceJ: 11111_1#11_04126 22222_2#22_04126
+flgL: 11111_1#11_04152 22222_2#22_04152
+ybhO_2: 11111_1#11_04116 22222_2#22_04116
+msyB: 11111_1#11_04121 22222_2#22_04121
+hpaI: 11111_1#11_04073 22222_2#22_04073
+yedV: 11111_1#11_04061 22222_2#22_04061
+mdoC: 11111_1#11_04117 22222_2#22_04117
+nanE: 11111_1#11_04097 22222_2#22_04097
+csgF: 11111_1#11_04108 22222_2#22_04108
+sigE: 11111_1#11_04058 22222_2#22_04058
+flgE: 11111_1#11_04145 22222_2#22_04145
+hpcD: 11111_1#11_04071 22222_2#22_04071
+hpaX: 11111_1#11_04074 22222_2#22_04074
+mdtH: 11111_1#11_04134 22222_2#22_04134
+yccJ: 11111_1#11_04084 22222_2#22_04084
+yjhC: 11111_1#11_04101 22222_2#22_04101
+ghrA: 22222_2#22_04103 11111_1#11_04103
+csgB: 11111_1#11_04111 22222_2#22_04111
+wrbA: 11111_1#11_04085 22222_2#22_04085
+sglT: 11111_1#11_04096 22222_2#22_04096
+cbpM: 11111_1#11_04077 22222_2#22_04077
+flgI: 11111_1#11_04149 22222_2#22_04149
+hpaR: 11111_1#11_04066 22222_2#22_04066
+hpcC_1: 11111_1#11_04068 22222_2#22_04068
+copR: 11111_1#11_04062 22222_2#22_04062
+agp: 11111_1#11_04083 22222_2#22_04083
+hpaB: 11111_1#11_04065 22222_2#22_04065
+group_33: 11111_1#11_04114 22222_2#22_04114
+mdoH: 11111_1#11_04119 22222_2#22_04119
+flgD: 11111_1#11_04144 22222_2#22_04144
+cbpA: 11111_1#11_04078 22222_2#22_04078
+putA: 11111_1#11_04089 22222_2#22_04089
+hpaC: 11111_1#11_04064 22222_2#22_04064
+flgG: 11111_1#11_04147 22222_2#22_04147
+rutR: 11111_1#11_04087 22222_2#22_04087
+flgK: 11111_1#11_04151 22222_2#22_04151
+group_56: 11111_1#11_04088 22222_2#22_04088
+pepD_2: 11111_1#11_04060 22222_2#22_04060
+csgC: 11111_1#11_04113 22222_2#22_04113
+csgD: 11111_1#11_04110 22222_2#22_04110
+hpcG: 11111_1#11_04072 22222_2#22_04072
+ycdY: 11111_1#11_04105 22222_2#22_04105
+scsC: 11111_1#11_04081 22222_2#22_04081
+flgF: 11111_1#11_04146 22222_2#22_04146
+phoH: 11111_1#11_04092 22222_2#22_04092
+flgH: 11111_1#11_04148 22222_2#22_04148
+group_52: 11111_1#11_04091 22222_2#22_04091
+resA: 11111_1#11_04082 22222_2#22_04082
+yceI_2: 11111_1#11_04125 22222_2#22_04125
+bssS: 11111_1#11_04129 22222_2#22_04129
+yidK: 11111_1#11_04095 22222_2#22_04095
+group_47: 11111_1#11_04086 22222_2#22_04086
+mdoG: 11111_1#11_04118 22222_2#22_04118
+yiiy: 11111_1#11_04099 22222_2#22_04099
+solA: 11111_1#11_04128 22222_2#22_04128
+group_93: 11111_1#11_04120 22222_2#22_04120
+scsB: 11111_1#11_04080 22222_2#22_04080
+ymdB: 11111_1#11_04115 22222_2#22_04115
+ybbH_2: 11111_1#11_04093 22222_2#22_04093
+putP: 11111_1#11_04090 22222_2#22_04090
+hpaG: 11111_1#11_04067 22222_2#22_04067
+nanM: 11111_1#11_04098 22222_2#22_04098
+scsA: 11111_1#11_04079 22222_2#22_04079
+rnz: 11111_1#11_04076 22222_2#22_04076
+ycdX: 11111_1#11_04104 22222_2#22_04104
+nanT_3: 11111_1#11_04100 22222_2#22_04100
+hpcC_2: 11111_1#11_04069 22222_2#22_04069
+flgA: 11111_1#11_04141
+grxB: 11111_1#11_04133
+mviN: 11111_1#11_04138
+group_12: 11111_1#11_04055
+yceH: 11111_1#11_04136
+pipB2_2: 11111_1#11_04056
+flgC: 11111_1#11_04143
+yceE: 11111_1#11_04122
+htrB_2: 11111_1#11_04123
+mviM: 11111_1#11_04137
+csgA: 22222_2#22_04112
+flgN: 11111_1#11_04139
+rimJ: 11111_1#11_04135
+flgB: 11111_1#11_04142
+group_31: 22222_2#22_04141
+group_14: 11111_1#11_04112
+yceB: 11111_1#11_04132
+pyrC: 11111_1#11_04131
+flgM: 11111_1#11_04140
+group_17: 11111_1#11_04124
diff --git a/t/data/expected_summary_statistics.txt b/t/data/expected_summary_statistics.txt
new file mode 100644
index 0000000..cd3d36c
--- /dev/null
+++ b/t/data/expected_summary_statistics.txt
@@ -0,0 +1,5 @@
+Core genes (99% <= strains <= 100%) 1
+Soft core genes (95% <= strains < 99%) 1
+Shell genes (15% <= strains < 95%) 24
+Cloud genes (0% <= strains < 15%) 4
+Total genes (0% <= strains <= 100%) 30
diff --git a/t/data/expected_uneven_sequences.fa b/t/data/expected_uneven_sequences.fa
new file mode 100644
index 0000000..c9f0e0c
--- /dev/null
+++ b/t/data/expected_uneven_sequences.fa
@@ -0,0 +1,18 @@
+>1
+aNN
+>2
+aaN
+>3
+aaa
+>4
+aaaaNN
+>5
+aaaaaN
+>6
+aaaaaa
+>7
+aaaaaaaNN
+>8
+aaaaaaaaN
+>9
+aaaaaaaaa
diff --git a/t/data/expected_union_of_groups.gg b/t/data/expected_union_of_groups.gg
new file mode 100644
index 0000000..b6c4dd7
--- /dev/null
+++ b/t/data/expected_union_of_groups.gg
@@ -0,0 +1,7 @@
+group_1: 1_1 2_1 3_1
+group_3: 1_3 3_3
+group_4: 2_4 3_4
+group_2: 1_2 2_2
+group_7: 2_7
+group_5: 3_5
+group_6: 1_6
diff --git a/t/data/genbank_gbff/genbank1.gff b/t/data/genbank_gbff/genbank1.gff
new file mode 100644
index 0000000..d89711b
--- /dev/null
+++ b/t/data/genbank_gbff/genbank1.gff
@@ -0,0 +1,195 @@
+##gff-version 3
+##sequence-region CVAX01000001 1 489098
+# conversion-by bp_genbank2gff3.pl
+# organism Salmonella enterica subsp. enterica serovar Typhi
+# Note Salmonella enterica subsp. enterica serovar Typhi genome assembly 10426_1#28, scaffold ERS325254SCcontig000001, whole genome shotgun sequence.
+# date 02-APR-2015
+CVAX01000001 GenBank region 1 489098 . + 1 ID=CVAX01000001;Dbxref=BioProject:PRJEB3215,taxon:90370;Name=CVAX01000001;Note=Salmonella enterica subsp. enterica serovar Typhi genome assembly 10426_1#28%2C scaffold ERS325254SCcontig000001%2C whole genome shotgun sequence.;collection_date=1994;country=Viet Nam;date=02-APR-2015;isolation_source=Not known;mol_type=genomic DNA;organism=Salmonella enterica subsp. enterica serovar Typhi;serovar=H58;strain=dtc71
+CVAX01000001 GenBank gene 358 1212 . - 1 ID=ERS325254_00002;Name=kdsA;locus_tag=ERS325254_00002
+CVAX01000001 GenBank mRNA 358 1212 . - 1 ID=ERS325254_00002.t01;Parent=ERS325254_00002
+CVAX01000001 GenBank CDS 358 1212 . - 1 ID=ERS325254_00002.p01;Parent=ERS325254_00002.t01;Dbxref=GI:804224942;eC_number=2.5.1.55;Name=kdsA;codon_start=1;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004730486.1;locus_tag=ERS325254_00002;product=2-dehydro-3-deoxyphosphooctonate aldolase;protein_id=CQU24961.1;transl_table=11;translation=length.284
+CVAX01000001 GenBank exon 358 1212 . - 1 Parent=ERS325254_00002.t01
+CVAX01000001 GenBank gene 1250 2059 . - 1 ID=ERS325254_00003;Name=ERS325254_00003
+CVAX01000001 GenBank mRNA 1250 2059 . - 1 ID=ERS325254_00003.t01;Parent=ERS325254_00003
+CVAX01000001 GenBank CDS 1250 2059 . - 1 ID=ERS325254_00003.p01;Parent=ERS325254_00003.t01;Dbxref=GI:804224943;Name=ERS325254_00003;codon_start=1;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004730487.1;product=regulator;protein_id=CQU25012.1;transl_table=11;translation=length.269
+CVAX01000001 GenBank exon 1250 2059 . - 1 Parent=ERS325254_00003.t01
+CVAX01000001 GenBank gene 2063 2452 . - 1 ID=ERS325254_00004;Name=sirB2;locus_tag=ERS325254_00004
+CVAX01000001 GenBank mRNA 2063 2452 . - 1 ID=ERS325254_00004.t01;Parent=ERS325254_00004
+CVAX01000001 GenBank CDS 2063 2452 . - 1 ID=ERS325254_00004.p01;Parent=ERS325254_00004.t01;Dbxref=GI:804224944;Name=sirB2;codon_start=1;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004730488.1;locus_tag=ERS325254_00004;product=regulator;protein_id=CQU25030.1;transl_table=11;translation=length.129
+CVAX01000001 GenBank exon 2063 2452 . - 1 Parent=ERS325254_00004.t01
+CVAX01000001 GenBank gene 2449 3282 . - 1 ID=ERS325254_00005;Name=prmC;locus_tag=ERS325254_00005
+CVAX01000001 GenBank mRNA 2449 3282 . - 1 ID=ERS325254_00005.t01;Parent=ERS325254_00005
+CVAX01000001 GenBank CDS 2449 3282 . - 1 ID=ERS325254_00005.p01;Parent=ERS325254_00005.t01;Dbxref=GI:804224945;eC_number=2.1.1.-;Name=prmC;codon_start=1;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_001570225.1;locus_tag=ERS325254_00005;product=N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase;protein_id=CQU25049.1;transl_table=11;translation=length.277
+CVAX01000001 GenBank exon 2449 3282 . - 1 Parent=ERS325254_00005.t01
+CVAX01000001 GenBank gene 3282 4364 . - 1 ID=ERS325254_00006;Name=prfA;locus_tag=ERS325254_00006
+CVAX01000001 GenBank mRNA 3282 4364 . - 1 ID=ERS325254_00006.t01;Parent=ERS325254_00006
+CVAX01000001 GenBank CDS 3282 4364 . - 1 ID=ERS325254_00006.p01;Parent=ERS325254_00006.t01;Dbxref=GI:804224946;Name=prfA;codon_start=1;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004730490.1;locus_tag=ERS325254_00006;product=peptide chain release factor 1 (RF-1);protein_id=CQU25068.1;transl_table=11;translation=length.360
+CVAX01000001 GenBank exon 3282 4364 . - 1 Parent=ERS325254_00006.t01
+CVAX01000001 GenBank gene 4405 5661 . - 1 ID=ERS325254_00007;Name=hemA;locus_tag=ERS325254_00007
+CVAX01000001 GenBank mRNA 4405 5661 . - 1 ID=ERS325254_00007.t01;Parent=ERS325254_00007
+CVAX01000001 GenBank CDS 4405 5661 . - 1 ID=ERS325254_00007.p01;Parent=ERS325254_00007.t01;Dbxref=GI:804224947;eC_number=1.2.1.70;Name=hemA;codon_start=1;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004730491.1;locus_tag=ERS325254_00007;product=glutamyl-tRNA reductase;protein_id=CQU25084.1;transl_table=11;translation=length.418
+CVAX01000001 GenBank exon 4405 5661 . - 1 Parent=ERS325254_00007.t01
+CVAX01000001 GenBank gene 5975 6598 . + 1 ID=ERS325254_00008;Name=hemM;locus_tag=ERS325254_00008
+CVAX01000001 GenBank mRNA 5975 6598 . + 1 ID=ERS325254_00008.t01;Parent=ERS325254_00008
+CVAX01000001 GenBank CDS 5975 6598 . + 1 ID=ERS325254_00008.p01;Parent=ERS325254_00008.t01;Dbxref=GI:804224948;Name=hemM;codon_start=1;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004730492.1;locus_tag=ERS325254_00008;product=outer membrane lipoprotein;protein_id=CQU25103.1;transl_table=11;translation=length.207
+CVAX01000001 GenBank exon 5975 6598 . + 1 Parent=ERS325254_00008.t01
+CVAX01000001 GenBank gene 6595 7446 . + 1 ID=ERS325254_00009;Name=ipk;locus_tag=ERS325254_00009
+CVAX01000001 GenBank mRNA 6595 7446 . + 1 ID=ERS325254_00009.t01;Parent=ERS325254_00009
+CVAX01000001 GenBank CDS 6595 7446 . + 1 ID=ERS325254_00009.p01;Parent=ERS325254_00009.t01;Dbxref=GI:804224949;eC_number=2.7.1.-,2.7.1.148;Name=ipk;codon_start=1;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004730493.1;locus_tag=ERS325254_00009;product=isopentenyl monophosphate kinase;protein_id=CQU25122.1;transl_table=11;translation=length.283
+CVAX01000001 GenBank exon 6595 7446 . + 1 Parent=ERS325254_00009.t01
+##FASTA
+>CVAX01000001
+GCTTCCAGAATTCGTACGTTTTTCCATTCACACAATTTTCTTAATATGCTGCCTACTGCC
+CTACGCTTCTCTCCATAGAACGCTTGTCTTCGGTATTTGGGCGCGAAAACTATGTGATAT
+TTACAGTTCCATCGGGTGTGCGCTAAGCTCTTTTCGTCCCCCATTGGGACCCCCTTTTGA
+TTTCTTGTTGAACTTTTGCAGTCGCCAGACCGCAAGATGTTTTAACAAATCAAAAGGGGT
+TTTAATAACTGGCTTAAAGCTGAAAGCTTTCCGGAACCCCCAGCCTAGCTGGGGGTTTTC
+CATAGACAAAAAAGCCGGATAGTATCTTATCCGGCCTACACAAGCTAAAAACCGCAATCA
+GTTCTCGGTATCCAGCTCGTCGAAGCTTTTCACCAAATCATCAATCGCTTTTATCTGGGT
+CAGGAACTGCTCCAGTTTCGCCAGCGGCAGCGCGGAAGGACCGTCGCACTTCGCGTTAGC
+CGGGTCCGGATGCGACTCCAGGAACAGGCCCGCCAGACCGACAGCCATACCGGCGCGCGC
+CAGCTCGGTCACCTGACCACGACGACCGCCCGAGGCAGCGCCAAATGGGTCGCGGCATTG
+CAGCGCATGGGTAACGTCGAAAATCACCGGCGAGTTGCCGGAGACCTTTTTCATCACGCT
+AAAGCCCAGCATATCCACCACCAGGTTGTCATAACCGAAGTTCGCGCCGCGATCGCACAG
+AATCACCTTATCGTTACCGCCCTCATGGAACTTATCCACGATATTGCCCATCTGACCCGG
+GCTTACAAACTGCGGCTTTTTCACGTTAATCACAGCGCCGGTTTTCGCCATCGCTTCCAC
+CAGGTCGGTCTGGCGCGCCAAAAACGCCGGGAGCTGAATCACGTCAACCACATCAGCCAC
+AGGCTGCGCCTGGCTGGCTTCATGGACGTCAGTGATCACTTTTACGCCAAATGTCTGTTT
+GAGTTCCTGGAAGATTTTCATCCCTTCTTCCAGACCCGGCCCACGGTAAGAGTGAATAGA
+GGAACGGTTGGCTTTATCAAAAGAGGCCTTGAACACGTAAGGAATACCCAGCTTCTGGGT
+AACGGTTACGTAGTGCTCACAAATGCGCATTGCCAGATCGCGTGACTCCAGCACGTTCAT
+ACCGCCAAACAGCACAAACGGCAGGTCATTTGCCACCTTAATGTCGCCAATGTTAACCAC
+TTTTTGTTTCATAGGATCGCCTTACACTTATAGGTAAAATGTCGGTTAATTAATGTAGAA
+CAATTTGCTTGTGCGCAATGGTGTTGATCTGCGCACGAATCATTTCGCTGATCGGGTCTT
+CCGGACACTGTTCAACGAAGTAGCTTAAATCAGTCAGCGCAACGTGTTCACACTCAAGCT
+GCGCGTAGATCAACCCGCGGTCACGGATTTCGTAAGGATCTTCCGGGTTAAATTGCAACA
+ATGCTTCGCTAACGCGCAGCGCCAGCTCCATTTGCCGTTCCTCCATCAGCGAGGATTTCA
+GCGTATCCAGTAGCTTACGAATCACTTCGGCGTTATCCGCTTCGTCCAAATCTTCGTTAA
+ACAACTCGGCGACCGGACTAATATTGCCTTTTAACCAGACTTCGAGGGTATGTTCATCAA
+GCGTTTCACCGTTGAACGGGTTAATCAGCCACATTTCTCCTTCCAGCGATTCAATACGCA
+AAATCAGCTGCGTTGGGAAGATAACGGGCACCAACGGCAAATCAAGACGGTTTGCTATCC
+ATAATAAAATAGCGCCCAACGATACAGCGCTCCCCTGGCGTTTTTTCAGGACTTTATCGA
+GCCATAAAGCATCAGAAAGACGGTAGACGCCGCGGGAATCCGTGAACCCCCACTCGCCGT
+AAAAAAGTGCCAGCAATTTTTCCAGTTGCTCATCCTGAGACAGGAGCTGGCTAATTTCTT
+CCTGCGCCAGACTGACCAGACGTTCCAGTTCGTCGTAGACAAACTGCGTGGGAAAATCCA
+GGCGAATCATCTCTGATGCCAGGATCATGCCATCACACAGCGGCGCATTGTTAAATTCGA
+AATCAGCTAACGACCTCATGACTTACCCCAGTAACGGTATTTTTGTGGTGGCGAGTTTAA
+TGATGATGTACAGCACCACCAGCGCCAGCGGGAAAGCGATAAAACGCGCCTGCTGGCTGC
+GCGCCTGACGATAATCAAGCGCAATAAAACCCAAAACGATGTAGATGATAACGCCAAACA
+GTTTTTCAGTCAGCCATGAGCCCGACTCCGTGAATGGCAGGATGTGCGTTTTAACGATTA
+ACCCAATACCGCTAAGCAGTAACAGGGTATCTATGACGGGAGGCACGATTCGTGTCCAGC
+GCGCGGCGGCCAACGCATGGCCGCAATAGCGCCACCAGTAACGAGCGACAAACAAACTGA
+CGGAGAGCGCAACACAAATAAGATGAAGCGTGAGCAACATTGCAATTGTCATGGCGTAAA
+ACGCCCGCAGGCCACGCGTTCATTGCCACCATAATCACGACACGTTTCTACATCCGTGTA
+ACCAGACCGCCTGAAAGCCGCTCTTACCGCTTCGCCCTGCCGCCAACCGTGTTCCAGCAG
+CAGGAAGCCGCCGGGCGTTAACATCTGGCGGGCATTATCGATAATATGCGTAAGATCCGC
+CATACCGTTTTCGTCCGCCACCAACGCTGAGCGCGGTTCAAAGCGTACATCGCCTTCGCT
+AAGGTGCGGGTCCTGCGCGTCAATGTAGGGCGGATTGCTGACAATCATGTCGAACTGCTG
+CCCCGATAGTGCGCTGAACCAACAACTTTGCAGTATACGCACATTCCGGATAGCCAAATG
+TTCCGCGTTGCGTATCGCCAGCGCAACCGCATCAGGCATACGATCGACCGCAGTCACCTC
+GCAATCCGGTCGCTCGCAGGCCAGCGCCAGCGCAATCGCGCCGGTTCCGGTGCCTAAATC
+CAGAATACGACAGGTTTTGACCGGCAATCGCGCCAACGCCTGTTCAACCAGACATTCGGT
+ATCCGGGCGCGGGATTAGCGTGGCGGGAGAAACGAAGAGCGGCAGCGACCAAAATTCGCG
+TAAGCCCGTCAGGTACGCAATGGGTTCGCCCTGTTTACGCCGCTGCAGCAGCTCCGCGAG
+CTGTTGTTGCTGGACATCGGTAAGCGGCGTTTCGCCAAAGGCCATGATATACGTCCGCCT
+CTTGCCCGTAACGTACTCAAGCAGGATCTCGGCGTCGCGCCGGGGGCTGTCGCTGTCCCG
+GAGCTGGTTTACCGCCTCATGTAGCCAGTGCTGAAAATCCATTATTCCTGCTCGGACAAC
+GCGGCTAACAGGTCAGCCTGGTGTTCCTGAACAATCGGCTCAATCAGCATATCCAGCTTA
+CCTTCCATCGTTTCATCAAGGCGATATAACGTCAGATTAATACGATGATCGGTCACGCGC
+CCCTGCGGGAAATTATAGGTCCGGTTACGATCGCTGCGATCGCCGCTGCCAAGCAGGTTG
+CGGCGCGTTGACGCCTCGGCCTGCTGGCGTTTTGCCGTTTCGGCGGCGTGAATGCGCGCC
+CCGAGCACCGAGAGCGCTTTCGCTTTGTTTTTATGCTGCGAACGCTCGTCCTGGCATTCC
+ACCACGATGCCGGTCGGCAAGTGGGTAATACGGATAGCGGAGTCGGTGGTGTTAACGTGC
+TGACCGCCCGCGCCGGAAGAACGAAACGTATCAATGCGCAGATCCGCCGGGTTAATATCC
+GGCAGCTCGGCTTCCGGCAGCTCCGGCATCACGGCGACGGTACAGGCGGAGGTATGGATA
+CGCCCCTGCGACTCGGTCGCCGGAACACGCTGTACGCGGTGTCCGCCGGACTCAAATTTC
+AGTCGGCCATACACGCCGTCGCCGCTGATTTTGGCGATGATCTCTTTATAACCGCCATGC
+TCGCCTTCGCTCATGCTCATGATCTCCACGCGCCAGCGGCGCGCTTCGGCATAACGGCTG
+TACATGCGGAACAGATCGCCGGCAAACAGCGCGGCTTCGTCGCCGCCAGTGCCGGCGCGA
+ACCTCAAGGAACGCGTTTCGTTCATCGTCCGGATCTTTCGGCAGCAGCAGTACCTGTAAC
+TGTTGCTCCAGTTGTTCGCTTTTTTCTTTCGCTTCGCGCAGTTCTTCCTGCGCCATTTCC
+CGCATTTCAGGATCGTCGAGCATCATCTGAGCCGTCTCGATATCGTCCTGAACCTGTTGC
+CAGTCCGTAAAACAGCGAGAAACGTCGCTTAATTGCGCATATTCGCGCGACAATGCGCGA
+AAGCGGTCCTGGTCGGCGATAATTCCCGCATCGCCCAGCAACGCCTGAACTTCCTCATGG
+CGTTCGTGCAGGGCTTCCAGTTTGGCAACGATAGAAGGCTTCATAGGCGTAAATTCACCC
+TGTAAAAAAGTGTGGTGTGTGCTGCTACTCCAGCCCGAGGCTGTCGCGCAGAATATTCAG
+GCGTTCGTCATCCCCGTCACGGGCAGCCTGTTGAAGTGATTTCGTTGGCGCATGAATCAG
+GCGGTTGGTCAGTTTCCATGCCAGATCCTGCAAGATGGCTTGCGCATCACCGCCCTGTTG
+AAGGGCCGACAGCGCTTTGGTAGTCAGTTCGTCACGAATCTGCTCCGACTGACTACGGTA
+TTCCCGAATGGTCTCGCTGGCCCCCTGGGCGCGTAGCCAGGCCATAAACTCGCTGGCTTC
+CTGCTCAACAATCGTTTCCGCTTCCACCGCCGCAGCCTGACGCTGCGCCAGATTATGCGA
+AATGATGCTCTGTAAATCATCGACGCTATAAAGATAAGCGTTCGCCAGTTTGCCGACTTC
+CGGCTCAACGTCGCGCGGTACGGCGATATCCACCAGCAGCATCGGCTGGTTGCGACGGCT
+TTTTAATGCGCGCTCCACCATGCCTTTACCGATAATCGGCAGCGGGCTGGCGGTCGAACT
+GATGATAATATCGGCATCCTGCAAGCGGGCGTCGATATCGCTGAGCGAGATAACCTCAGC
+GCCAACCTCATCCGCCAGGGCTTGCGCGCGCTCGCGGGTTCGGTTGGCGATAATCATCTT
+TTGTACTTTATGCTCGCGCAGGTGACGCGCCACCAGTTCAATAGTTTCGCCCGCGCCAAC
+TAACAGTACAGTGACCGTCGAGAGCGATTCAAAGATTTGGCGGGCGAGCGTACAGGCGGC
+AAACGCGACGGAGACGGCGCTGGCGCCGATATCGGTTTCAGTCCGCACTCGCTTGGCGAC
+GGAAAAAGACTTCTGAAACATTCGCTCCAGCGCGCTGGCGTTAAGGTGGCCTTTTTGCGA
+ATCCGCAAACGCTTTTTTCACCTGACCGAGGATTTGCGGTTCGCCCAGCACCAGTGAATC
+CAGACCGCTGGCGACGCGCATCAGGTGGCTGACGGCGTCATTGTCCTGATGCCAGTACAG
+ACTGTTGCGCAGATCGTCCTCGTTCAGGTTATGGTAATCGCATAACCAGCGGATCAGCGC
+TTCTTGCAGGTTATCCTGCTCTTCCACGCTCAAATACAGCTCTGTACGGTTACAGGTTGA
+CAGCACGACCCCGCCCTGCACCATTGGCTGCGCAAGCAGGCTGTCCAGCGCCTGATCAAG
+CGTGTCCGGCGAAAACGTTACGCGTTCTCGCAGCGATACAGGTGCCGTTTTATGGTTAAT
+ACCGAGTGCTAAAAGGGTCATGTCTGCGGGAGTAGTACCAGCGTTGATATGGTTAGTCTG
+CTTGCATCATACAGGATGCGCGTGGTCAATAAAAGAGAGAGCCCCCTTTTGGAGTAATTG
+GCAGCGCTCGCTAATTTGATGATTTAAGACAACTTGAAAGTAGACGATGTCACCAGGCGG
+CGCTAGCATTAAAGGCTATAACTGTAACCGATAGCAAAAATTTGCCGAATCGCGGCGCGA
+ACGTTTTTACAGCTTGCCGGTTCAGTTTTCAGGCCTGATAAGCGTAACGCCTTCAGGCAA
+TTATTGCACCGTATCACAAGGATTCGTCATCACTATGACCCTGCCCGATTTTCGCCTGAT
+TCGTCTACTGCCGTTAGCAAGCCTGGTTCTCACCGCCTGTACGCTTCCTGGGCATAAAGG
+CCCGGGCAAGAGCCCGGATTCCCCTCAGTGGCGCCAGCATCAGCAAGAGGTGCGTCATCT
+GAATCAATACCAGACGCGCGGCGCCTTTGCTTACATCTCAGATGATCAGAAAGTCTATGC
+GCGCTTCTTCTGGCAACAGACCGGACAGGATCGCTACCGCCTGCTGCTTACCAACCCGCT
+GGGCAGCACCGAGCTGGAGCTTAACGCCCAGCCGGGCAACGTCCAGTTGGTGGATAACAA
+AGGCCAGCGTTATACCGCCGATGACGCCGAAGAGATGATCGGCAAACTCACCGGGATGCC
+GATTCCGTTAAACAGCCTGCGGCAGTGGATCCTCGGTCTGCCTGGCGATGCCACCGACTA
+CAAACTGGACGACCAGTACCGCCTGAGCGAAGTGAACTACCACCAGGATGGTAAAAACTG
+GAAAGTGGTTTACGGTGGCTATGACAGCAAAACGCAGCCTGCCATGCCAGCCAATATGGA
+GCTTTCAGATGGCAGTCAGCGCATTAAGCTGAAAATGGATAACTGGATTGTGAAATGATG
+ACCCATTGGCCTTCTCCGGCAAAATTAAATCTGTTTTTATATATCACCGGACAGCGTGCA
+GACGGCTACCACACGCTGCAGACGCTGTTTCAGTTTCTGGATTATGGCGACACACTCCAC
+ATCGAACCGCGTCACGATGGCGAAATCCATTTATTAACGCCGGTAACCGGCGTTGAAAAT
+GAAGACAATCTGATCGTCCGCGCCGCGCGGCTGTTGATGAAAGTCGCCTCGGAGAGTGGA
+CGCCTGCCCGCCGGAAGCGGCGCGGATATCAGCATTGAGAAGCGCCTTCCCATGGGCGGC
+GGTCTGGGTGGCGGCTCGTCTAACGCCGCGACCGTTCTGGTGGCGCTCAATCATCTTTGG
+CAATGCGGGCTTTCCATTGATGAACTGGCGACGCTCGGCCTGACGCTCGGCGCCGACGTC
+CCGGTCTTTGTTCGTGGCCACGCCGCGTTTGCCGAAGGCGTAGGCGAAATATTAACGCCG
+GTGAATCCGCCGGAAAAATGGTATCTGGTCGCGCACCCTGGCGTAAGCATTCCGACGCCA
+GTTATCTTTAAAGATCCTCAATTGCCGCGTAATACGCCAAAAAGGTCAATAGATACGTTA
+CTAAAATGTGAATTCAGCAATGATTGCGAGGTTATCGCAAGAAAACGTTTTCGCGAGGTT
+GATGCGGCGCTTTCCTGGCTGTTAGAATACGCGCCGTCGCGCCTGACTGGGACAGGGGCC
+TGTGTCTTTGCTGAATTCGATACAGAGTCTTGTGCTCGCCAGGTGCTTGAGCAAGCCCCG
+GAATGGCTCAATGCTTTTGTGGCGAAGGGTGTTAACCTTTCCCCATTGCATCGAGAGTTA
+CTCTAACGCATTCGGGTTTCAGGAAGATGGCGAAATGACGAGTCGCCGGTCATATATGCC
+GTATTTGACCGGTGTGAGGCATTGATACCAGCGCACATGAAACGTGAATGAAGACGAGTA
+AGCCGGGCAAGCTGAGCTTCGGTGACAACGTCACCTTGTTCCAGACGTTGCATCGCGCTC
+TTTAATACACCGCCTGGATAGGATTTTGCCTGGCCCGCACAGTTTTCGGCAGATTCTTTC
+CACCAATGGACGCATGCCTGAGGTTCTTCTCGTGCCTGATATGAAGCTTTTTGCTGGTAA
+CGCCACCCCGGAACTAGCACAACGTATTGCCAACCGCCTGTACACTTCTCTCGGCGACGC
+CGCCGTAGGTCGCTTTAGCGACGGCGAAGTCAGCGTACAAATCAACGAAAATGTACGCGG
+TGGTGATATTTTCATCATCCAGTCCACTTGTGCCCCAACCAACGACAACCTGATGGAATT
+GGTCGTTATGGTTGATGCCCTGCGTCGTGCTTCCGCAGGTCGTATCACCGCCGTTATCCC
+CTACTTTGGCTATGCACGTCAGGACCGTCGCGTACGTTCCGCCCGTGTGCCGATTACCGC
+AAAAGTTGTCGCTGACTTCCTGTCCAGCGTCGGCGTTGACCGCGTTCTCACCGTAGATCT
+GCATGCTGAACAGATCCAGGGCTTCTTTGACGTTCCGGTTGATAACGTGTTCGGTAGCCC
+AATCCTGCTCGAAGATATGCTGCAACTGAATCTGGATAACCCAATCGTGGTTTCCCCGGA
+TATTGGCGGCGTGGTTCGTGCCCGCGCTATCGCTAAGCTGCTGAACGATACCGATATGGC
+TATCATTGATAAACGTCGTCCGCGCGCGAACGTTTCTCAGGTGATGCACATCATCGGCGA
+CGTCGCTGGCCGTGACTGCGTGCTGGTTGATGATATGATCGATACCGGCGGTACTCTGTG
+CAAAGCAGCAGAAGCATTGAAAGAACGTGGCGCTAAACGCGTGTTTGCCTACGCGACGCA
+CCCGATCTTCTCAGGCAATGCGGCAAACAACCTGCGCAACTCCGTTATTGACGAAGTCGT
+TGTCTGTGACACCATTCCGCTGACCGACGAAATCAAAGCGCTGCCGAACGTGCGTACTTT
+GACCCTGTCAGGTATGCTGGCCGAAGCGATTCGCCGTATCAGCAACGAAGAATCGATTTC
+CGCCATGTTCGAGCATTGATCGAACCCGGATCTGAAACCCGCTGCGGCGGGTTTTTTTGT
+CTGTAACACCCTTTTATATGACTTATGCCTCCTTCACCTGCCATTTAGTTGACAGATGAT
+GCGCTCATGGATGAAACATTATTGTGAACAAATTATTTTCCTCACATGTGATGCCTTTCC
+GCGCTCTCATCGATGCTTGCTGGAAAGAAAAATATACCGCCTCCCGGTTCACCCGTGATG
+TGATAGCCGGGATCACCGTCGGGATTATTGCTATCCCGCTGGCGATGGCGCTGGCAATTG
+GCAGTGGCGTTGCGCCGCAGTATGGCCTCTATACCTCCGCTGTCGCCGGGATCGTGATCG
+CGCTAACCGGCGGCTCGCGCTTTAGCGTTTCCGGCCCTACCGCCGCGTTTGTGGTGATTT
+TGTATCCGGTGTCGCAACAGTTTGGTCTGGCGGGCCTACTGGTCGCCACGCTGATGTCGG
+GCTTCTTCCTGATCCTTTTCGGCCTGGCGAGACTGGGGCGATTGATTGAATATATCCCGG
+TGTCGGTCACGTTGGGTTTTACCTCAGGGATTGGTATTACCATCGGTACCATGCAGATTA
\ No newline at end of file
diff --git a/t/data/genbank_gbff/genbank1.gff.proteome.faa.expected b/t/data/genbank_gbff/genbank1.gff.proteome.faa.expected
new file mode 100644
index 0000000..20955ec
--- /dev/null
+++ b/t/data/genbank_gbff/genbank1.gff.proteome.faa.expected
@@ -0,0 +1,49 @@
+>ERS325254_00002.p01
+MKQKVVNIGDIKVANDLPFVLFGGMNVLESRDLAMRICEHYVTVTQKLGIPYVFKASFDK
+ANRSSIHSYRGPGLEEGMKIFQELKQTFGVKVITDVHEASQAQPVADVVDVIQLPAFLAR
+QTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFHEGGNDKVILCDRGANFGYDNLVVD
+MLGFSVMKKVSGNSPVIFDVTHALQCRDPFGAASGGRRGQVTELARAGMAVGLAGLFLES
+HPDPANAKCDGPSALPLAKLEQFLTQIKAIDDLVKSFDELDTEN*
+>ERS325254_00003.p01
+MRSLADFEFNNAPLCDGMILASEMIRLDFPTQFVYDELERLVSLAQEEISQLLSQDEQLE
+KLLALFYGEWGFTDSRGVYRLSDALWLDKVLKKRQGSAVSLGAILLWIANRLDLPLVPVI
+FPTQLILRIESLEGEMWLINPFNGETLDEHTLEVWLKGNISPVAELFNEDLDEADNAEVI
+RKLLDTLKSSLMEERQMELALRVSEALLQFNPEDPYEIRDRGLIYAQLECEHVALTDLSY
+FVEQCPEDPISEMIRAQINTIAHKQIVLH*
+>ERS325254_00004.p01
+MTIAMLLTLHLICVALSVSLFVARYWWRYCGHALAAARWTRIVPPVIDTLLLLSGIGLIV
+KTHILPFTESGSWLTEKLFGVIIYIVLGFIALDYRQARSQQARFIAFPLALVVLYIIIKL
+ATTKIPLLG*
+>ERS325254_00005.p01
+MDFQHWLHEAVNQLRDSDSPRRDAEILLEYVTGKRRTYIMAFGETPLTDVQQQQLAELLQ
+RRKQGEPIAYLTGLREFWSLPLFVSPATLIPRPDTECLVEQALARLPVKTCRILDLGTGT
+GAIALALACERPDCEVTAVDRMPDAVALAIRNAEHLAIRNVRILQSCWFSALSGQQFDMI
+VSNPPYIDAQDPHLSEGDVRFEPRSALVADENGMADLTHIIDNARQMLTPGGFLLLEHGW
+RQGEAVRAAFRRSGYTDVETCRDYGGNERVACGRFTP*
+>ERS325254_00006.p01
+MKPSIVAKLEALHERHEEVQALLGDAGIIADQDRFRALSREYAQLSDVSRCFTDWQQVQD
+DIETAQMMLDDPEMREMAQEELREAKEKSEQLEQQLQVLLLPKDPDDERNAFLEVRAGTG
+GDEAALFAGDLFRMYSRYAEARRWRVEIMSMSEGEHGGYKEIIAKISGDGVYGRLKFESG
+GHRVQRVPATESQGRIHTSACTVAVMPELPEAELPDINPADLRIDTFRSSGAGGQHVNTT
+DSAIRITHLPTGIVVECQDERSQHKNKAKALSVLGARIHAAETAKRQQAEASTRRNLLGS
+GDRSDRNRTYNFPQGRVTDHRINLTLYRLDETMEGKLDMLIEPIVQEHQADLLAALSEQE
+*
+>ERS325254_00007.p01
+MTLLALGINHKTAPVSLRERVTFSPDTLDQALDSLLAQPMVQGGVVLSTCNRTELYLSVE
+EQDNLQEALIRWLCDYHNLNEDDLRNSLYWHQDNDAVSHLMRVASGLDSLVLGEPQILGQ
+VKKAFADSQKGHLNASALERMFQKSFSVAKRVRTETDIGASAVSVAFAACTLARQIFESL
+STVTVLLVGAGETIELVARHLREHKVQKMIIANRTRERAQALADEVGAEVISLSDIDARL
+QDADIIISSTASPLPIIGKGMVERALKSRRNQPMLLVDIAVPRDVEPEVGKLANAYLYSV
+DDLQSIISHNLAQRQAAAVEAETIVEQEASEFMAWLRAQGASETIREYRSQSEQIRDELT
+TKALSALQQGGDAQAILQDLAWKLTNRLIHAPTKSLQQAARDGDDERLNILRDSLGLE*
+>ERS325254_00008.p01
+MTLPDFRLIRLLPLASLVLTACTLPGHKGPGKSPDSPQWRQHQQEVRHLNQYQTRGAFAY
+ISDDQKVYARFFWQQTGQDRYRLLLTNPLGSTELELNAQPGNVQLVDNKGQRYTADDAEE
+MIGKLTGMPIPLNSLRQWILGLPGDATDYKLDDQYRLSEVNYHQDGKNWKVVYGGYDSKT
+QPAMPANMELSDGSQRIKLKMDNWIVK*
+>ERS325254_00009.p01
+MMTHWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTLHIEPRHDGEIHLLTPVTGV
+ENEDNLIVRAARLLMKVASESGRLPAGSGADISIEKRLPMGGGLGGGSSNAATVLVALNH
+LWQCGLSIDELATLGLTLGADVPVFVRGHAAFAEGVGEILTPVNPPEKWYLVAHPGVSIP
+TPVIFKDPQLPRNTPKRSIDTLLKCEFSNDCEVIARKRFREVDAALSWLLEYAPSRLTGT
+GACVFAEFDTESCARQVLEQAPEWLNAFVAKGVNLSPLHRELL*
diff --git a/t/data/genbank_gbff/genbank2.gff b/t/data/genbank_gbff/genbank2.gff
new file mode 100644
index 0000000..2904c83
--- /dev/null
+++ b/t/data/genbank_gbff/genbank2.gff
@@ -0,0 +1,282 @@
+##gff-version 3
+##sequence-region CVBR01000001 1 488985
+# conversion-by bp_genbank2gff3.pl
+# organism Salmonella enterica subsp. enterica serovar Typhi
+# Note Salmonella enterica subsp. enterica serovar Typhi genome assembly 10426_1#57, scaffold ERS325340SCcontig000001, whole genome shotgun sequence.
+# date 02-APR-2015
+CVBR01000001 GenBank region 1 488985 . + 1 ID=CVBR01000001;Dbxref=BioProject:PRJEB3215,taxon:90370;Name=CVBR01000001;Note=Salmonella enterica subsp. enterica serovar Typhi genome assembly 10426_1#57%2C scaffold ERS325340SCcontig000001%2C whole genome shotgun sequence.;collection_date=1994;country=Viet Nam;date=02-APR-2015;isolation_source=Not known;mol_type=genomic DNA;organism=Salmonella enterica subsp. enterica serovar Typhi;serovar=H58;strain=ct1-65
+CVBR01000001 GenBank gene 79 726 . - 1 ID=ERS325340_00001;Name=narL_1;locus_tag=ERS325340_00001
+CVBR01000001 GenBank mRNA 79 726 . - 1 ID=ERS325340_00001.t01;Parent=ERS325340_00001
+CVBR01000001 GenBank CDS 79 726 . - 1 ID=ERS325340_00001.p01;Parent=ERS325340_00001.t01;Dbxref=GI:804333227;Name=narL_1;codon_start=1;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002147204.1;locus_tag=ERS325340_00001;product=transcriptional regulator NarP;protein_id=CQU31315.1;transl_table=11;translation=length.215
+CVBR01000001 GenBank exon 79 726 . - 1 Parent=ERS325340_00001.t01
+CVBR01000001 GenBank gene 2716 3507 . + 1 ID=ERS325340_00003;Name=ERS325340_00003
+CVBR01000001 GenBank mRNA 2716 3507 . + 1 ID=ERS325340_00003.t01;Parent=ERS325340_00003
+CVBR01000001 GenBank CDS 2716 3507 . + 1 ID=ERS325340_00003.p01;Parent=ERS325340_00003.t01;Dbxref=GI:804333228;Name=ERS325340_00003;codon_start=1;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002041506.1;product=side tail fiber protein;protein_id=CQU31351.1;transl_table=11;translation=length.263
+CVBR01000001 GenBank exon 2716 3507 . + 1 Parent=ERS325340_00003.t01
+CVBR01000001 GenBank gene 4176 6542 . + 1 ID=ERS325340_00004;Name=sspH2;locus_tag=ERS325340_00004
+CVBR01000001 GenBank mRNA 4176 6542 . + 1 ID=ERS325340_00004.t01;Parent=ERS325340_00004
+CVBR01000001 GenBank CDS 4176 6542 . + 1 ID=ERS325340_00004.p01;Parent=ERS325340_00004.t01;Dbxref=GI:804333229;eC_number=6.3.2.-;Name=sspH2;codon_start=1;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002244314.1;locus_tag=ERS325340_00004;product=secreted effector protein;protein_id=CQU31395.1;transl_table=11;translation=length.788
+CVBR01000001 GenBank exon 4176 6542 . + 1 Parent=ERS325340_00004.t01
+CVBR01000001 GenBank gene 7163 7239 . - 1 ID=ERS325340_00005;Name=ERS325340_00005
+CVBR01000001 GenBank tRNA 7163 7239 . - 1 ID=ERS325340_00005.r01;Parent=ERS325340_00005;Name=ERS325340_00005;inference=COORDINATES: profile:Aragorn:1.2.36;product=tRNA-Pro
+CVBR01000001 GenBank exon 7163 7239 . - 1 Parent=ERS325340_00005.r01;Name=ERS325340_00005
+##FASTA
+>CVBR01000001
+TAGAGCGCAGTATCCGGCTGGCGCAGGAGAAATAAGACCCTGACGGCCCGGTGGCGTGGC
+GCCACCGGGCCTGGCTTGTTACTGCATTCCGCGTGTTTGTAAAAATAGAATGGTCGCCGC
+GACGCGCGAGCGCACGTTTAGCTTGCGAAGTAGATTACGAATGTGCACCTTAACCGTCTG
+CTCAGAAATATTCAGTACTGACGCAATCTGTTTGTTAGAAAGCCCCTGCGCCAGCTCATG
+CAAGACATCTAACTCTCGTTCGGTCAGGATACTAAAGGGATCTTCCTGCGCGCCAAACCG
+TTCACGCTCACGCAGATATTCATTGACCCGATCGCTAAAGACTTTACCGCCGTTAGCGCC
+TTTGCGAATGGCCTCCAGCAGCACTTCCGGATCGCTATCTTTGAGCAGATAACCGTCGGC
+GCCGGCGTCGATCAGCGCGTAGATGTCGCTGGCGGAATCCGAGACGGTAAGAATAATAAT
+TTGCGCCGTCACACCATCCCGGCGTAGCGCGTTCAGGGTATCTAACCCGCTCAGACCTTT
+CATATTCAGATCCAGCAGGATCAGATCGGGCTCAATGCGATTCGCCAGATCGATCGCACT
+CGCCCCGTCACCCGCTTCGGCAACGACATAAAAAGCCGGGTCCAGTTCCAGTAATTGACG
+AATACCTCGCCGCATAAGTGGATGGTCGTCCACAATAAGCACCTGAAAAGGTGTTACTTC
+AGGCATGCTATATCTCCTGAGTTTTATTAGAATGATTATTGTTTTCAGCGCGGAAATCGT
+CCAGATTTGCCACATTGTCAAGCGCGTAAATTTTACCTTAATTAGTGCATGGGTAAGTAG
+TAAAACCTGTGACAGGCGAGTCATTAGCTGAACGATAGAAAGGATAAAACAACCTGTTGT
+GAGAGAAAACAGAATACTCCCTGAAGTTGAATACTGGTCTGGACGCTTTTTTCGGACAAT
+GTGACATAACAGAAGTGTGGCATATGTAGCTGCGCCCTTGCGTCCGTAAGTCCAGACTAT
+CTTTACTGGCAGGAAATTCCTTATTAAAAGTCATAGCGTCTAAAGATTTTCATTATTAAC
+AAATTATTTTAATTGAATTTATTTATGGTTTTATTAATGCCAATGAAATACATCTGAGCA
+GAACGAATAAACCGCGACATCTGTTAAATTAAATATTAAGTCAATAGCAGAGGTATTTTT
+ATGCGATAAAGAGATTCTGACGATATTCTTATCATAAATGAAAATGTGGTCAGGAATGAG
+CGTCATTCACTTATAACTTATCCTGGATGTGCCTGAACAACACTCGCGGCGTTTTGAGCA
+CCCGTTGGGGCGACTCAAGGGGAGAACGTAGTGTGGATGCTATATCAGCCGTTTCTGTGA
+GCGTAAGCGTGGCGTAGAAAATTTTAAATATGTTAGCCGGTTAAAAATAACTATTGACAT
+TGAAATGGTGGTGGAGTGTATATGAAGAGAATATTTATATATCTATTATTACCTTGTGCA
+TTCGCATGTTCTGCTAATGATAATGTTTTTTTGGCAAGGGCAACAAGCATCAGATCTCTT
+TTGCTGCGGGAGAAAGTATAAGAAGAGGAGGGGTTGAGCACTTATATACGGCTTTTCTGA
+CATACAGTGAACCCAGCGATTTTTTCTTTTTACAGGCAAGAAATAATCTGGAGTTAGGAG
+GATTTAAGGCTAAGGGTAGCGATGATTGCAGTAAACATTCTGGCAGCGTTCCCTGTAATA
+AATATAACCAGGGCGTATTGGGTATCTCGAAGGATGTGGCGCTGGTTCATTTCGCTGGTA
+TCTATACCGGTATTGGTCTGGGGGCTTATATAAAATCTAAGTCGCGAGATGATATGCGTG
+TCAATTCTGCATTTACCTTTGGAGAAAAAGCGTTTCTTGGCTGGAACTTTGGGGCTTTTT
+CTACAGAAGCTTATATCCGGCATTTCTCGAATGGATCACTTACGGATAAAAATTCAGGGC
+ATAATTTTGTAGGTGCTTCAATTAGTTATAATTTCTGAAGTTGAATAACAATTAGCGAGT
+TGCTGGCTGAAGGAGTAATTAATCACCGTACGTTGTCTACAAAACGTGTTGTGAATAGCC
+GATCGTTATCGACCCTATGGCGACAGGGAGGCTAATTGTTAGCGACAAAGGCGTGGTAGG
+CCGTTTACCTTACCAGAACGTTTTATTATTGCTGCGACAGATTGCTTACTCATTTACCTG
+CCACTGCAAACATTTTTTCCAGTATAGGGTGTAGATGCGCTTTTTCTGTTTTAGTACAAA
+CATGGTTTACGTTAGTTGCCTGCATTGACTTTACTGTGACCACTGCACAGGAAAGATGTC
+CAATCAGTTCATGCAAAATCAGTTCATGCAAAATAACGTCTCTGGCATCAGCTAACTTTT
+TAATTGTAGGCATAAAAAAACCAGCCCTGACAGGCTGGTTTTCAAGGGGAATTTTGGTCG
+GCAGCTTCATCCGCAGCATCTGCGGAGAGCAGCGCAGGTACGGCGACCACAAAAGCCGGG
+GAGGCATCAGCCAGCGCGGCGTCGGCTGACACAGCCAGAACGGCGGCAGCCGCCTCGTCA
+TCAGCATCGTAGGCATCCACCCACGCCGCCGCATCTGATACCAGCGCATCACTGGCAGCG
+CAAAGCAGAGCTGCAGCCGGAGAATCGGCAACCAGAGCCGAAGAGGCCGCGAAACGGGCC
+GAGGATATCGCAGACGTGATTTCCCTGGAAGATGCAAGCCTGACGAAAAAAGGTATCGTT
+AAATTAAGCAGTGCCACGGACAGTGACAGCGAAGCGCTGGCGGCCACACCAAAGGCGGTA
+AAAACCGTTATGGGTGAGGTACGGACCAAAGCGCCGCTGGACAGCCCGGCATTCACTGGA
+ACGCCGACCACACCGACGCCGCCAGGCGATGCTAAAGGGCTTCAGACAACAAACGCGGAG
+TTTGTCCGCAAACTGATTGCCGCGCTGGTTGGTTCCGTACTGGAGCCACTGGACACCCTG
+CAGGAACTGGCTGACGCGTTGGGAAATGATCCGAACTTTGCCACCACGGTACTGAATAAA
+CTGGCGGGCAAGCAGCCGCTGGACGAAACCCTGACGGCGCTGTCAGGAAAAAGCGTTGAC
+GGTCTTATCGAATACGTTGGTTTGCGAGAAACCATAAGTCGTGCCGCCGATGCATTACAA
+AAATCACAGAATGGCGGCGATATTCCGGACAAGGATTTGTTTGTGCGTCGTATCGGTGCC
+GCGCGAGCGTTTGATGGCGCAGTTATTATCGGCTGTGATGATAATCCGTGGACGACGGCG
+GAGTTTATCGTCTGGCTGGAGTCTCAGGGCGCATTCAATCACCCTTACTGGATGTGTCGT
+GGCTCCTGGTCTTACGCTTATAACAAAATCATCACGGATACTGGCTGCGGTAATATCTGT
+CTCGCTGGCGCAGTGATTGAGGTAATGGGAGTGCGTGGCGCGATGACTATTCGGGTGACA
+ACGTCCCATTCAGTATCTGGTTGGTGATACGTGGGTGACAGCCCCAAGTGTATAAGAAGG
+AATAATTATGACAGCGGAAAAAAAATAAAAAGAACAAACAGTTTTTAAATATTAAAAATT
+TCATTCCGTATGCACCGGAACCAGATGACACATTATTCGCCGATGCGGCGTATCTTAAAT
+CAGAGGATGGTCAGGACTGGTATGGGTGCCAGCAATTATTTTCAGCAGACACGCTGAAAA
+TTACCTACGACGATAACGATGTTATTACGTGTATTACGCGTGATGTTTCCGGGCTGTGGC
+CTGCTGGCCAGAGCGTTGCAGAGTTGCCTGATACGGATGAAAACCGTCGCGCTGATATTC
+ATGCTGCTGGCAGTTTAAAGACGGTAAAGTCGTTCAAAGGGTTTATTCGCCGGAAGAGCT
+GCGCAGGCAGGCAGAATCGAAAATTGAACGCCCGGGCGTTGATACCGGATGATCTGGTCA
+TCGTGGAAAGCGACCCTGAAAAAATCGACACTTTAGCTGTAAAATGACAGTCCCGCCATC
+CGGTCATCATAACGGATTTTTCTTCTGCACCTTCTGAAGCCCGCCATGTCAGGACGACCA
+TGAATCCGCCGATAACCTTATTGTGAAATTAAGACCAGGAAGAGATGATGTCTGCCGGAC
+AGATACTATATGTAAATTTATAAAGGTTTTTTGTTATGCCCTTTCATATTGGAAGCGGAT
+GTCTTCCCGCCACCATCAGTAATCGCCGCATTTATCGTATTGCCTGGTCTGATACCCCCC
+CTGAAATGAGTTCCTGGGAAAAAATGAAGGAATTTTTTTGCTCAACGCACCAGACTGAAG
+CGCTGGAGTGCATCTGGACGATTTGTCACCCGCCGGCCGGAACGACGCGGGAGGATGTGA
+TCAACAGATTTGAACTGCTCAGGACGCTCGCGTATGCCGGATGGGAGGAAAGCATTCATT
+CCGGCCAGCACGGGGAAAATTACTTCTGTATTCTGGATGAAGACAGTCAGGAGATATTGT
+CAGTCACCCTTGATGATGCCGGGAACTATACCGTAAATTGCCAGGGGTACAGTGAAACAC
+ATCGCCTCACCCTGGACACAGCACAGGGTGAGGAGGGCACAGGACACGCGGAAGGGGCAT
+CCGGGACATTCAGGACATCCTTCCTCCCTGCCACAACGGCTCCACAGACGCCAGCAGAGT
+ATGATGCTGTCTGGTCAGCGTGGAGAAGGGCTGCACCCGCAGAAGAGTCACGCGGCCGTG
+CAGCAGCGGTACAGAAAATGCGTGCCTGCCTGAATAATGGCAATGCAGTGCTTAACGTGG
+GAGAATCAGGTCTTACCACCTTGCCAGACTGTTTACCCGCGCATATTACCACACTGGTTA
+TTCCTGATAATAATCTGACCAGCCTGCCGGCGCTGCCGCCAGAACTGCGGACGCTGGAGG
+TCTCTGGTAACCAGCTGACTAGCCTGCCGGTGCTGCCGCCAGGACTACTGGAACTGTCGA
+TCTTTAGTAACCCGCTGACCCACCTGCCGGCGCTGCCGTCAGGACTATGTAAGCTGTGGA
+TCTTTGGTAATCAACTGACCAGCCTGCCGGTGTTGCCGCCAGGGCTACAGGAGCTGTCGG
+TATCTGATAACCAACTGGCCAGCCTGCCGGCGCTGCCGTCAGAATTATGTAAGCTGTGGG
+CCTATAATAACCAGCTGACCAGCCTGCCGACGTTGCCGTCAGGGCTACAGGAGCTGTCGG
+TATCTGATAACCAACTGGCCAGCTTGCCGACGCTGCCGTCAGAATTATATAAGCTGTGGG
+CCTATAATAATCGGCTGACCAGCCTGCCGGCGTTGCCGTCAGGACTGAAGGAGCTGATTG
+TATCTGGTAACCGGCTGACCAGTCTGCCGGTGCTGCCGTCAGAACTGAAGGAGCTGATGG
+TATCTGGTAACCGGCTGACCAGCCTGCCGATGCTGCCGTCAGGACTACTGTCGCTGTCGG
+TCTATCGTAACCAGCTGACCCGCCTGCCGGAAAGTCTCATTCATCTGTCTTCAGAGACAA
+CCGTAAATCTGGAAGGGAACCCACTGTCTGAACGTACTTTGCAGGCGCTGCGGGAGATCA
+CCAGCGCGCCTGGCTATTCAGGCCCCATAATACGATTCGATATGGCGGGAGCCTCCGCCC
+CCCGGGAAACTCGGGCACTGCACCTGGCGGCCGCTGACTGGCTGGTGCCTGCCCGGGAGG
+GGGAACCGGCTCCTGCAGACAGATGGCATATGTTCGGACAGGAAGATAACGCCGACGCCT
+TCAGCCTCTTCCTGGACAGACTGAGTGAGACGGAAAACTTCATAAAGGACGCGGGGTTTA
+AGGCACAGATATCGTCCTGGCTGGCACAACTGGCTGAAGATGAGGCGTTGAGAGCAAACA
+CCTTTGCTATGGCAACAGAGGCAACCTCAAGCTGCGAGGACCGGGTCACATTTTTTTTGC
+ACCAGATGAAGAACGTACAGCTGGTACATAATGCAGAAAAAGGGCAATACGATAACGATC
+TCGCGGCGCTGGTTGCCACGGGGCGTGAGATGTTCCGTCTGGGAAAACTGGAACAGATTG
+CCCGGGAAAAGGTCAGAACGCTGGCTCTCGTTGATGAAATTGAGGTCTGGCTGGCGTATC
+AGAATAAGCTGAAGAAATCACTCGGGCTGACCAGCGTGACGTCAGAAATGCGTTTCTTTG
+ACGTATCCGGCGTGACGGTTACAGACCTTCAGGACGCGGAGCTTCAGGTGAAAGCCGCTG
+AAAAAAGCGAGTTCAGGGAGTGGATACTGCAGTGGGGGCCGTTACACAGAGTGCTGGAGC
+GCAAAGCGCCGAAACGCGTTAACGCGCTTCGTGAAAAGCAAATATCGGATTATGAGGAAA
+CGTACCGGATGCTGTCTGACACAGAGCTGAGACCGTCTGGGCTGGTCGGTAATACCGATG
+CAGAGCGCACTATCGGAGCAAGAGCGATGGAGAGCGCGAAAAAGACATTTTTGGATGGCC
+TGCGACCTCTTGTGGAGGAGATGCTGGGGAGCTATCTGAACGTTCAGTGGCGTCGTAACT
+GATGCACCAGGTGAATGAGGTGCGGTGCGACAAAGATATTCCCGGACGAACAACATCAGA
+CAGTACGGATGATGTACAGGTGAAATAGGGGAGACTTCTTCAGTCAGGGCGCGGCGCAAC
+TTTTTCGATGATAACGCGCCGCGCGCCGGTAGCGAGAAGCCGATGGAAGTACTGGATCAC
+CTGAATGCAAAGAAGGGCAGGGGAAAGCTGTACTTTGCCGGGGAGGGTATCCAGCAACAG
+TGGGCTATGAAGAGAAACATACTGTCATCCCGATATACCACCCGCTATGAAGACCTGCTT
+CAGGTTAAGTGACAGGTTTACCCTGATTTTCAAATTTCTGATGTGATGGTGTGCCGCAGC
+CACATTGTATGCAAGAACGGGCTGCGGCAAACTGGCGATCGTTCGATAGTGCGTGTATTG
+AATAGTTACCAGTCGTGGCGGATTCTACTGGTTAAGGATGACTAATCAATGTATTTAAGT
+CATCTGTTCAACTTTTCGCGTTGGAGGGAGCTTGAAGTCAATTTGCAGTGACCTTCGATA
+GCTATTTCACCATCATTTCACCATTTGCAAATTGGATATATAAAAAAACCAGCCCTGGCA
+GGCTGGCTTTTAAGGGGAATTTTGGTCGGCACGAGAGGATTTGAACCTCCGACCCCCGAC
+ACCCCATGACGGTGCGCTACCAGGCTGCGCTACGTGCCGACTTGTGGGTGCTAATACTAC
+CTCTTTCCAACGCGAATGCAAGGGGAAACGGTGCTAACTGATTTATAATTAATCAGTTAG
+CGATAAAACGTTTCTCTTCTGTTAGCACTTGCAGCAGCAGACTGAGCTGCGGCTTCTGAT
+CTTTGATCTTCTCGCCGTGTAAGTCATAGGTCTGATAATGACCGTTATTATTGAGCACCA
+GGGTCATTTGCGGCGTCGTGATTGCCAGCGTACTGCCGTCTGCCGCCGTTACCCAGTTAT
+GACGACGTGGAACGGTAAAGATGTCCTGGCCCTGTGAATATTCGTTCGCTGGCGTGCTGA
+CATGTAACAGGCGTTGCATCAACGTGGTCATCACATCGGTATGATCGGTAAGCACATTAA
+TACGCTGCGCAGGCGTCCCCGGCCAGTGGATCACCAGCGGTACTTGCAGATGACCTTGCG
+ACCAGTCGAAGCGATTTTCTTCCGGCGTCAACGGTATGCCGCGTCCTGCGGTAATGATCA
+CGACAGTATTGTCGAATTTACCGGCCTCTCGCAGCGCGTTCAGAACCCGATTGATTTGCG
+CATCCACGTCGCTGGCGGCACTGGCGTAACGCTTAACAAAATTTTTCTGGTTACTGTCAT
+CAATGTTAGTACCGTTAAACGATATCCATGAGAACCAGCGGTTATCTTCCTGTGCGTAGC
+GCCCAAGCCAGTCTATCCACTGGCTGGCCGTTTGCGCATCAGACTGCGTTTGCGCTGCCG
+GCATCGAGAAATCGGACAGTAATGCCTGACGATAAAGCGGGCTGGCGAAGCCATCCGAAG
+AAAACAGTCCCAGTTGGTAGCCTTGCTGATTCAACGCGGTAATGAGCGCCGCAGGCGTTC
+TGGTGGATAACACGCCATCCATATAGCCTGGCGATATGCCATAGAACAGGCCGAAAATAC
+CGTTATCAGTGGTATTCCCTGAACTCATATGACGGGTGAAGTCGATGTTTTGCTCGGCAA
+ATGTAGCCAGCTCCGGCATCTGCTTCTCAAAGCGAGAATAGTTCAGGCCGTCTACGGTAA
+TGAGCAGCACATTCTGACCGGTGCCCATATCGCGATAGTGCAAATTGCTGAGCGGGTACT
+GAACGGAGACCGCTTCCGGATTGCCTTGCTCTACCAGACGGCGCTGATATTCCTGCGCAT
+CCAGCAGACCGTGTTTTTCAAGAAAACGTCGCGCCGTCATCGGATAAGAGAGCGGCAGGT
+TTGCCCGCTGCATGGTAATCGGCCGGTAAAAATTAGCGTCTGCCCAGATGTAGATAAGAT
+GCGATGCGATAAAGGAGACGAAAAAGAATGCCGCAAGCGGCCTTGCGAAATGGCGGCGGC
+GCGTGAGACTGCGCAGCTTTTGCCAACTCCATGTCGCAAATAGCATCTCAATCAATAAGA
+TAACTGGCACGCTAATAAACATAAGCTGCCAGTCGCGCGCCATTTCGTTCTGGTCAGGGT
+TGATGACCAGTTCCCAGACAATGGGGTTAAGATGCAGGTGAAAACGGGTAAAGACTTCGC
+TGTCGATAAGCAACAACGTCATACCCGCGGTCGCCAGAATGGCTGATAAAAACCGCATCA
+GCCGCTGGGACATCACGATAAACGTGAGCGGAAAAAGAATAAGCAAATAGGTGGCGAACA
+CCAGAAAGCTAAAGTGCCCGACAATGCTCAGGTAGGAGTATATGCGACCCGCAAGCGTTG
+TCGGCCAGTCGGCGACAAACAGGTAACGGCTGCCGAGCAACGTAGCCAACAGTATATTGA
+ACAGAGCGAACCAGTGCCCCCAGCTAACCATCTGGGAGACTTTTTCACGGTAGCGCTGAC
+GATGAGTTACCATACCTGTCGCTTGTTTCTCCGGAGTCGGCTTTTTAGTGCGCGTTGTCT
+TCGCTAATCGAAGACTGCAAGGCGCGGGCAAAAGAGTTCGCAATCGCCTGGCGTTGAGCC
+GGCGCCACGCTGGTGTTGATAAGGTTGGTGACCATATTTCCCAGTACCATCAGGGAAAGA
+TCGGTCGGCGCCTTATGTTTTTCCAGTACACTGAGCAGTTCGCTCAGCAGTTGTTCAACA
+TGTTCATCACTATAGCGGGAGAGTTGTGGCATAAATCAAAATCTGTTTGTTCATGAAAGG
+GCAACATATTACCGTAGCAACAGTTTTTTTTCTGCATTTTTATCCCCTAAATCATTCGCG
+TTACGGATAACGCCTGAAATGACAGGGCGATTGCTTGCGTCTTCCGGCAGGCGGTGGTTG
+AATACCGCCCGGTCTTAAAGGAGAGTTTATCATGAGTCTGGATATCAACCAGATTGCCCT
+GCACCAGCTTATCAAGCGCGATGAGCAAAATCTTGAGCTGGTCTTGCGCGATTCATTGCT
+GGAGCCGACAACCACCGTTGTCGAGATGGTGGCTGAACTGCATCGGGTCTATAGCGCCAA
+GAATAAGGCGTATGGCCTGTTTAATGAAGAGAGTGAACTGGCGCAAGCGCTGCGGTTGCA
+ACGTCAGGGGGAAGAAGATTTTCTTGCCTTTAGCCGGGCGGCGACCGGACGCCTGCGTGA
+CGAACTGGCGAAATATCCCTTTGCGGACGGCGGCATTGTATTGTTCTGCCATTATCGTTA
+CCTGGCGGTGGAGTATCTGCTGGTTACGGTACTGAACAACCTGAGCAGTATGCGGGTCAA
+TGAAAATCTGGACATTAACCCGACGCATTATCTTGATATCAACCATGCGGATATCGTGGC
+GCGTATCGATCTTACCGAGTGGGAAACTAATCCGCAATCGACCCGCTACCTGACGTTCCT
+GAAAGGTCGGGTAGGGCGCAAGGTCGCTGACTTCTTTATGGATTTCCTCGGCGCCAGCGA
+AGGGTTGAACGCCAAAGCGCAGAATCGCGGCCTGTTGCAGGCAGTGGATGATTTCACCGC
+AGAAGCGCAGTTGGATAAAGCAGAACGTCAGAACGTGCGTCAGCAGGTGTACAGCTACTG
+CAACGAGCAGTTACAAGCCGGGGAAGAGATTGAGCTGGAATCGCTGTCTAAAGAGCTTTC
+CGGCGTCAGTGAAGTCAGCTTCAGCGAATTTACCGCCGAAAAAGGCTATGAGCTGGAAGA
+GAGCTTCCCGGCAGATCGCAGTACGCTACGCCAGTTAACCAAATATGCCGGCAGCGGCGG
+CGGGTTAACGATTAACTTTGATGCGATGCTACTGGGCGAGCGGATTTTCTGGGACCCGGC
+GACCGATACCCTGACTATCAAAGGGACGCCGCCGAATTTGCGCGATCAGTTGCAGCGACG
+CACGTCGGGCGGGAAATAAAGGCATACGACATAAAAGGACGCCGTAGTGAGTAAAGGAAT
+ACGTCAGAGGCCGCCTGTTAATTTCAGTTTATTTCGGCAGGTTTTGTATGCGCACATTGT
+CGCATTTTTGATGATGTTGATGCTCGGCATGGTGTTCACCGTTCTCTCGTTGGTACTGTT
+TTATACTTATGGCGCCAACTGGTTACTGAGCTTGTTCATATGCCCGCTGTTCTTGTTAAG
+TGGTTTATTCATTACTGGATTTGCTTTTAAATCAACCTGGTCCAGCATACGTTACTATTA
+CGACAAGGGGCAGTTGAAACGGTATGGACTCAATCTTGATGCAACTTTGACGCATAAAGA
+GAAGGTGGAAATACGCATCGATAATGCAAAGCGTCAAGTGCGTGTAGATGAACTGGAACT
+CCATGTCTTATTTGATTTTCAGTTTGATAGCAAGACATGGAGCTGCGGCGACTTACTGAC
+CAATGAAAAGGTATTTGATGCGTTGAATGATGGGCAAACGATACCAATACGAATTTTGCC
+ATGGAAACCGGAAAGTGCCAGCGTTCGTCAACGGGCATTATTCAATCGGCTTAAAGGTAT
+GAATACCGCGGCGGAAACTACAGATCCTCGATTAGGGGAGGCGCTAATTGAATGTGGCGA
+GGTGTAAGAAAGCAGAAAAGCAAAGTGGGTTCTCGTTGCTCTGCATGTCGTCAAATTCAA
+TTAAACGCATAAAAAAACCCCGCCGGGGCGGGGTTTTTCTTCAACTTCCAGGCGATTACG
+CGCGAACGAAGTCGATGTGAGTCAGCTTCGGTTTGTAAGCGTGACGCTGTACAGCCTGAG
+CTTTAACTTTTACTTCTTTACCGTCAACAACGAGGGTCAGAACTTCGCTGTAGAATTCAG
+CTTTAGCTTGCATGTTCATCACCTGGTCGTGGTCCAGTTCGATAGCAATCGGGGCTTCAG
+AACCGCCGTAGATGATTGCCGGGAACTTGTTAGCGGCGCGCAGGCGGCGGCTCGCACCCT
+TACCCTGCTCTTTACGTACTTCTGCGTTGATAGTAAACATTTAAATCTCTCTTTAATAAT
+TCCTGCTACAGGCGACCCAGCAACAGGTAAGTGATCTGCTTTGCGTATGCAAAGGCGGGC
+GGGATTCTATACTCAAATCGCCGTTACATCAATGAAAAGTACAATTAACCACGTAATTCG
+TGCGCCCGGCGGAAGCGGCCTTCATAGTCGAACACTTTTTCACGCACCTGCCAGTACTGG
+CCTTTCATCCGCGCGACCACAAAATCGGGATGCCGCAACAGCGCCTGCTGCGCGACAATA
+TCCGCCGCCGTGATCCAGCGTAAAGGAACGCCGGGCGTGCGCGTATGCGGGCGAATAAAT
+AGCTGTTCGAAAGCGGTACGCTGGGCGGGCGTGTGCAAGCGGAAGCGCTCACTGACATCC
+GCGCCGTCCTCGTCATAGTAAGTGATTTTCAGCCATTCGCCTTTCTCATCCTGCCCATGC
+TGCATCGTCATTCCGCTACAGCGCAGGACTAACGCATCCTTGAGCCTGAGCGCCGCTTTT
+AACATATCGTCCGGGTCGACCAGAATGGCGTCACATTCCCGGCAGCGTCGGGCGGCAATA
+TCGTTTTCGGCATTACACTGCGGGCAGTTTTTGAAGCGAAAGCGAAAATCGCACTGCTCG
+CGATGGCCGTCGTCATCCTCAAACCAGCCCTGGCAGCGACGGCCAAAGTGTTCAATCAGC
+GTGCCGTCGGCAGTGGTTTTCCCCCAGAAGGTGTTGGCAAAGCCGCAGGCCGGGCAAAAT
+ACCTGGACAGGGACGTTATCGCTTTTTCCCTTCGGGCTACCGACCTCCGGGGCATACAGG
+TCGTGCGGGTTGCCTGCGTAATCAAGAATCAGGCAATCGGTCTTTCCCGGCGCAAGGCGC
+AGACCACGCCCGACAATTTGTTGGTAAAGACTAACTGACTCCGTGGGACGTAGAATCGCG
+ATGAGATCAACGTGTGGGGCGTCAAAGCCGGTGGTCAGTACCGAGACGTTAACCAGATAG
+CGAAAACGCTGCGCCTTGAAATTATCAATCAGCGCGTCGCGCTCGGGCCCTGGCGTATCG
+CCGGTAATCAGCGCCGCGTCGTCCGCCGGAAGCAGACCGACAATCTCTTTCGCATGTTCG
+ACCGTGGCGGCGAAAATCATCACGCCTTTGCGCGTTTGCGCAAATTCCATAATCTGGCTG
+ATGATGTGCGGCGTAATCCGCTGCTGCTTTTTCAGCTCGCGGTTCAGGTCGGCTTCGCTG
+AACAGCCCATTGCTTTGGGCCTGCAGGCGGCTGAAATCGTATTGGACCACTGGCATATCA
+AGCCGCTCAGGCGGCGTCAGATAGCCGTGTTTAATCATATAGCGCAGCGGCAGTTCATAA
+ATACAGTCGCGAAACAGAGCGTTGTCGTTGCCGCGCACCATACCGTGATAATGAAATTGA
+TAAATCCAGCCTTTTCCGAGGCGAAAAGGCGTGGCGGTGAGTCCAAGCAGACGTAAGTGA
+GGATTAACTTTACTCAGGTGAGTGAGGATTTGCTGATACTGACTGTCTTCATCGTCACCG
+ATGCGGTGGCATTCATCGACAATCAACAGCGAAAACTCCTCCTGGAAGGCGTCAAGATTA
+CGCGCCACCGACTGTACGCTGCCGAACACGACTTTGCCCTGACTCTCTTTACGTTTGAGT
+CCGGCGGCGAAAATATCCGCTTCCAGCCCCAGCGCGCAATATTTGGCGTGGTTCTGCGCG
+ACCAGCTCTTTCACATGCGCCAGCACCAGTACCCGTCCGCGGGCGACGCGCGCCAGTTCG
+GCGATCACCAGGCTTTTACCTGCGCCGGTCGGCAGAACAATCACGGCGGGCGTACGGTGG
+CGGCGAAAGTGGCTGAGCGTGGCGTCTACGGCTTCTTGCTGGTAGGGGCGGAGTGTAAAA
+ATCATGGTCTCACTACGTTAAACGGTTCCGGGAATAGTATGCCATGAATCATTTCCCTTG
+AGGGATATAGTTAGCCCGCTATACTGAGCGGATAGCAATTCCCTTTTTTCGGGTAGAATG
+CCCGATTTCCGTATTATTACAGGCTAAATCACACACATGCGACTTGATAAATTTATCGCT
+CAGCAGCTTGGCGTCAGCCGCGCTATTGCCGGGCGTGAAATTCGTGGTAACCGCGTTACC
+GTCGATGGCGACATCATTAAAAATGCGGCCTTCAAACTGCTCCCGGAACATGCGGTTGCG
+TATGACGGCAATCCCTTAGCGCAGCAACACGGGCCACGCTATTTTATGCTTAACAAGCCG
+CAGGGATACGTTTGTTCAACCGATGATCCCGATCATCCAACGGTGCTGTATTTCCTGGAT
+GAGCCGGTGGCGTATAAGCTGCATGCCGCAGGACGTCTGGATATCGATACTACCGGTCTG
+GTGTTAATGACAGATGACGGTCAGTGGTCGCACCGCATTACGTCGCCGCGCCATCACTGT
+GAAAAAACCTATCTGGTGACCCTGGAGTCGCCGGTGGCCGACGATACGGCAGCGCAATTT
+GCGAAAGGCGTGCAGTTGCATAATGAAAAAGATCTCACTAAACCCGCTACGCTGGAGGTG
+ATAACACCTGTGCAGGTCCGTCTGACCATCAGCGAAGGCCGTTATCATCAGGTGAAGCGG
+ATGTTTGCCGCAGTAGGCAATCGCGTTGTGGAACTGCACCGCGAACGGATTGGCGCCATT
+ACGCTGGATGAGAATCTGGCTCCCGGCGAGTACCGCCCGTTGACTGAAGAAGAAATCGCC
+AGCGTCGGCTAACTATCTCGTTAAATTCAGGAGTTCGATGTGACCACCCGGCAGCACTCT
+TCCTTTGCCATTGTCTTTATTCTTGGCCTGTTGGCCATGTTAATGCCGCTGTCGATTGAT
+ATGTATCTTCCAGCGCTGCCGGTGATTTCTGCGCAATTCGGCGTGCCTGCCGGTAGCGCG
+CAGATGACGCTCAGCACCTATATTCTGGGGTTTGCGCTGGGTCAGCTTATCTATGGACCG
+ATGGCGGATAGCCTCGGGCGTAAGCCGGTCATCCTGGGCGGGACGCTGGTATTTGCCGCT
+GCGGCGGTCGCCTGTGCGTTGGCGCAGACTATCGATCAACTGATCGTGATGCGTTTCTTT
+CACGGTTTGGTGGCTGCGGCGGCAAGCGTCGTCATCAATGCGCTGATGCGGGATATTTAT
+CCAAAGGAAGAGTTTTCGCGCATGATGTCATTTGTCATGCTGGTCACTACGATAGCGCCG
+TTAATGGCGCCCATTGTTGGCGGCTGGGTGTTGGTATGGTTAAGCTGGCACTATATCTTC
+TGGATACTGGCTATTGCGGCGATTCTGGCGTCAGTCATGATCTTTGCTTTGATTAAAGAG
+ACGCTGCCCGTTGAGCGGCGTCAGCCTTTTCATATTCGTACCACAATAGGTAACTTTGCC
+GCGTTGTTTCGCCACAAACGCGTACTGAGCTATATGCTGGCGAGCGGGTTCAGTTTTGCC
+GGTATGTTCTCTTTTTTGAGCGCGGGGCCGTTTGTCTATATCGAAATTAATCATGTTCCG
+CCGCAGGATTTCGGCTACTACTTCGCGTTGAACATCGTATTTCTGTTTGTGATGACGATT
+ATCAACAGCCGTTTTGTCAGACGGGTAGGGGCGCTAAACATGTTTCGGGCCGGGCTATGG
+ATTCAGTTTGCGATGGCGGTGTGGATGGTTTTCAGCGCGCTGATGGGCATTGGATTCTGG
+GCGCTGGTGGTTGGCGTTGCGGCGTTTGTCGGCTGTGTGTCGATGGTTTCGTCCAATGCG
+ATGGCGGTCATTTTGGATGAGTTTCCGCATATGGCCGGAACGGCGTCTTCGTTGGCGGGC
+ACTTTCCGCTTTGGTATTGGCGCTATCGTCGGCGCGTTGCTGTCGCTGGCTACCTTTAAC
+AGTGCGTGGCCGATGATCTGGTCGATTGCGCTTTGCGCCGCCTGTTCCATTCTGTTTTAT
diff --git a/t/data/genbank_gbff/genbank2.gff.proteome.faa.expected b/t/data/genbank_gbff/genbank2.gff.proteome.faa.expected
new file mode 100644
index 0000000..7805e26
--- /dev/null
+++ b/t/data/genbank_gbff/genbank2.gff.proteome.faa.expected
@@ -0,0 +1,26 @@
+>ERS325340_00001.p01
+MPEVTPFQVLIVDDHPLMRRGIRQLLELDPAFYVVAEAGDGASAIDLANRIEPDLILLDL
+NMKGLSGLDTLNALRRDGVTAQIIILTVSDSASDIYALIDAGADGYLLKDSDPEVLLEAI
+RKGANGGKVFSDRVNEYLRERERFGAQEDPFSILTERELDVLHELAQGLSNKQIASVLNI
+SEQTVKVHIRNLLRKLNVRSRVAATILFLQTRGMQ*
+>ERS325340_00003.p01
+VISLEDASLTKKGIVKLSSATDSDSEALAATPKAVKTVMGEVRTKAPLDSPAFTGTPTTP
+TPPGDAKGLQTTNAEFVRKLIAALVGSVLEPLDTLQELADALGNDPNFATTVLNKLAGKQ
+PLDETLTALSGKSVDGLIEYVGLRETISRAADALQKSQNGGDIPDKDLFVRRIGAARAFD
+GAVIIGCDDNPWTTAEFIVWLESQGAFNHPYWMCRGSWSYAYNKIITDTGCGNICLAGAV
+IEVMGVRGAMTIRVTTSHSVSGW*
+>ERS325340_00004.p01
+MPFHIGSGCLPATISNRRIYRIAWSDTPPEMSSWEKMKEFFCSTHQTEALECIWTICHPP
+AGTTREDVINRFELLRTLAYAGWEESIHSGQHGENYFCILDEDSQEILSVTLDDAGNYTV
+NCQGYSETHRLTLDTAQGEEGTGHAEGASGTFRTSFLPATTAPQTPAEYDAVWSAWRRAA
+PAEESRGRAAAVQKMRACLNNGNAVLNVGESGLTTLPDCLPAHITTLVIPDNNLTSLPAL
+PPELRTLEVSGNQLTSLPVLPPGLLELSIFSNPLTHLPALPSGLCKLWIFGNQLTSLPVL
+PPGLQELSVSDNQLASLPALPSELCKLWAYNNQLTSLPTLPSGLQELSVSDNQLASLPTL
+PSELYKLWAYNNRLTSLPALPSGLKELIVSGNRLTSLPVLPSELKELMVSGNRLTSLPML
+PSGLLSLSVYRNQLTRLPESLIHLSSETTVNLEGNPLSERTLQALREITSAPGYSGPIIR
+FDMAGASAPRETRALHLAAADWLVPAREGEPAPADRWHMFGQEDNADAFSLFLDRLSETE
+NFIKDAGFKAQISSWLAQLAEDEALRANTFAMATEATSSCEDRVTFFLHQMKNVQLVHNA
+EKGQYDNDLAALVATGREMFRLGKLEQIAREKVRTLALVDEIEVWLAYQNKLKKSLGLTS
+VTSEMRFFDVSGVTVTDLQDAELQVKAAEKSEFREWILQWGPLHRVLERKAPKRVNALRE
+KQISDYEETYRMLSDTELRPSGLVGNTDAERTIGARAMESAKKTFLDGLRPLVEEMLGSY
+LNVQWRRN*
diff --git a/t/data/genbank_gbff/genbank3.gff b/t/data/genbank_gbff/genbank3.gff
new file mode 100644
index 0000000..a3ec219
--- /dev/null
+++ b/t/data/genbank_gbff/genbank3.gff
@@ -0,0 +1,282 @@
+##gff-version 3
+##sequence-region CVBT01000001 1 489157
+# conversion-by bp_genbank2gff3.pl
+# organism Salmonella enterica subsp. enterica serovar Typhi
+# Note Salmonella enterica subsp. enterica serovar Typhi genome assembly 10426_1#50, scaffold ERS325326SCcontig000001, whole genome shotgun sequence.
+# date 02-APR-2015
+CVBT01000001 GenBank region 1 489157 . + 1 ID=CVBT01000001;Dbxref=BioProject:PRJEB3215,taxon:90370;Name=CVBT01000001;Note=Salmonella enterica subsp. enterica serovar Typhi genome assembly 10426_1#50%2C scaffold ERS325326SCcontig000001%2C whole genome shotgun sequence.;collection_date=1997;country=Viet Nam;date=02-APR-2015;isolation_source=Not known;mol_type=genomic DNA;organism=Salmonella enterica subsp. enterica serovar Typhi;serovar=H58;strain=ipt76
+CVBT01000001 GenBank gene 83 730 . - 1 ID=ERS325326_00001;Name=narL_1;locus_tag=ERS325326_00001
+CVBT01000001 GenBank mRNA 83 730 . - 1 ID=ERS325326_00001.t01;Parent=ERS325326_00001
+CVBT01000001 GenBank CDS 83 730 . - 1 ID=ERS325326_00001.p01;Parent=ERS325326_00001.t01;Dbxref=GI:804342840;Name=narL_1;codon_start=1;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002147204.1;locus_tag=ERS325326_00001;product=transcriptional regulator NarP;protein_id=CQU32483.1;transl_table=11;translation=length.215
+CVBT01000001 GenBank exon 83 730 . - 1 Parent=ERS325326_00001.t01
+CVBT01000001 GenBank gene 2720 3511 . + 1 ID=ERS325326_00003;Name=ERS325326_00003
+CVBT01000001 GenBank mRNA 2720 3511 . + 1 ID=ERS325326_00003.t01;Parent=ERS325326_00003
+CVBT01000001 GenBank CDS 2720 3511 . + 1 ID=ERS325326_00003.p01;Parent=ERS325326_00003.t01;Dbxref=GI:804342841;Name=ERS325326_00003;codon_start=1;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002041506.1;product=side tail fiber protein;protein_id=CQU32522.1;transl_table=11;translation=length.263
+CVBT01000001 GenBank exon 2720 3511 . + 1 Parent=ERS325326_00003.t01
+CVBT01000001 GenBank gene 4180 6546 . + 1 ID=ERS325326_00004;Name=sspH2;locus_tag=ERS325326_00004
+CVBT01000001 GenBank mRNA 4180 6546 . + 1 ID=ERS325326_00004.t01;Parent=ERS325326_00004
+CVBT01000001 GenBank CDS 4180 6546 . + 1 ID=ERS325326_00004.p01;Parent=ERS325326_00004.t01;Dbxref=GI:804342842;eC_number=6.3.2.-;Name=sspH2;codon_start=1;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002244314.1;locus_tag=ERS325326_00004;product=secreted effector protein;protein_id=CQU32561.1;transl_table=11;translation=length.788
+CVBT01000001 GenBank exon 4180 6546 . + 1 Parent=ERS325326_00004.t01
+CVBT01000001 GenBank gene 7167 7243 . - 1 ID=ERS325326_00005;Name=ERS325326_00005
+CVBT01000001 GenBank tRNA 7167 7243 . - 1 ID=ERS325326_00005.r01;Parent=ERS325326_00005;Name=ERS325326_00005;inference=COORDINATES: profile:Aragorn:1.2.36;product=tRNA-Pro
+CVBT01000001 GenBank exon 7167 7243 . - 1 Parent=ERS325326_00005.r01;Name=ERS325326_00005
+##FASTA
+>CVBT01000001
+GTGATAGAGCGCAGTATCCGGCTGGCGCAGGAGAAATAAGACCCTGACGGCCCGGTGGCG
+TGGCGCCACCGGGCCTGGCTTGTTACTGCATTCCGCGTGTTTGTAAAAATAGAATGGTCG
+CCGCGACGCGCGAGCGCACGTTTAGCTTGCGAAGTAGATTACGAATGTGCACCTTAACCG
+TCTGCTCAGAAATATTCAGTACTGACGCAATCTGTTTGTTAGAAAGCCCCTGCGCCAGCT
+CATGCAAGACATCTAACTCTCGTTCGGTCAGGATACTAAAGGGATCTTCCTGCGCGCCAA
+ACCGTTCACGCTCACGCAGATATTCATTGACCCGATCGCTAAAGACTTTACCGCCGTTAG
+CGCCTTTGCGAATGGCCTCCAGCAGCACTTCCGGATCGCTATCTTTGAGCAGATAACCGT
+CGGCGCCGGCGTCGATCAGCGCGTAGATGTCGCTGGCGGAATCCGAGACGGTAAGAATAA
+TAATTTGCGCCGTCACACCATCCCGGCGTAGCGCGTTCAGGGTATCTAACCCGCTCAGAC
+CTTTCATATTCAGATCCAGCAGGATCAGATCGGGCTCAATGCGATTCGCCAGATCGATCG
+CACTCGCCCCGTCACCCGCTTCGGCAACGACATAAAAAGCCGGGTCCAGTTCCAGTAATT
+GACGAATACCTCGCCGCATAAGTGGATGGTCGTCCACAATAAGCACCTGAAAAGGTGTTA
+CTTCAGGCATGCTATATCTCCTGAGTTTTATTAGAATGATTATTGTTTTCAGCGCGGAAA
+TCGTCCAGATTTGCCACATTGTCAAGCGCGTAAATTTTACCTTAATTAGTGCATGGGTAA
+GTAGTAAAACCTGTGACAGGCGAGTCATTAGCTGAACGATAGAAAGGATAAAACAACCTG
+TTGTGAGAGAAAACAGAATACTCCCTGAAGTTGAATACTGGTCTGGACGCTTTTTTCGGA
+CAATGTGACATAACAGAAGTGTGGCATATGTAGCTGCGCCCTTGCGTCCGTAAGTCCAGA
+CTATCTTTACTGGCAGGAAATTCCTTATTAAAAGTCATAGCGTCTAAAGATTTTCATTAT
+TAACAAATTATTTTAATTGAATTTATTTATGGTTTTATTAATGCCAATGAAATACATCTG
+AGCAGAACGAATAAACCGCGACATCTGTTAAATTAAATATTAAGTCAATAGCAGAGGTAT
+TTTTATGCGATAAAGAGATTCTGACGATATTCTTATCATAAATGAAAATGTGGTCAGGAA
+TGAGCGTCATTCACTTATAACTTATCCTGGATGTGCCTGAACAACACTCGCGGCGTTTTG
+AGCACCCGTTGGGGCGACTCAAGGGGAGAACGTAGTGTGGATGCTATATCAGCCGTTTCT
+GTGAGCGTAAGCGTGGCGTAGAAAATTTTAAATATGTTAGCCGGTTAAAAATAACTATTG
+ACATTGAAATGGTGGTGGAGTGTATATGAAGAGAATATTTATATATCTATTATTACCTTG
+TGCATTCGCATGTTCTGCTAATGATAATGTTTTTTTGGCAAGGGCAACAAGCATCAGATC
+TCTTTTGCTGCGGGAGAAAGTATAAGAAGAGGAGGGGTTGAGCACTTATATACGGCTTTT
+CTGACATACAGTGAACCCAGCGATTTTTTCTTTTTACAGGCAAGAAATAATCTGGAGTTA
+GGAGGATTTAAGGCTAAGGGTAGCGATGATTGCAGTAAACATTCTGGCAGCGTTCCCTGT
+AATAAATATAACCAGGGCGTATTGGGTATCTCGAAGGATGTGGCGCTGGTTCATTTCGCT
+GGTATCTATACCGGTATTGGTCTGGGGGCTTATATAAAATCTAAGTCGCGAGATGATATG
+CGTGTCAATTCTGCATTTACCTTTGGAGAAAAAGCGTTTCTTGGCTGGAACTTTGGGGCT
+TTTTCTACAGAAGCTTATATCCGGCATTTCTCGAATGGATCACTTACGGATAAAAATTCA
+GGGCATAATTTTGTAGGTGCTTCAATTAGTTATAATTTCTGAAGTTGAATAACAATTAGC
+GAGTTGCTGGCTGAAGGAGTAATTAATCACCGTACGTTGTCTACAAAACGTGTTGTGAAT
+AGCCGATCGTTATCGACCCTATGGCGACAGGGAGGCTAATTGTTAGCGACAAAGGCGTGG
+TAGGCCGTTTACCTTACCAGAACGTTTTATTATTGCTGCGACAGATTGCTTACTCATTTA
+CCTGCCACTGCAAACATTTTTTCCAGTATAGGGTGTAGATGCGCTTTTTCTGTTTTAGTA
+CAAACATGGTTTACGTTAGTTGCCTGCATTGACTTTACTGTGACCACTGCACAGGAAAGA
+TGTCCAATCAGTTCATGCAAAATCAGTTCATGCAAAATAACGTCTCTGGCATCAGCTAAC
+TTTTTAATTGTAGGCATAAAAAAACCAGCCCTGACAGGCTGGTTTTCAAGGGGAATTTTG
+GTCGGCAGCTTCATCCGCAGCATCTGCGGAGAGCAGCGCAGGTACGGCGACCACAAAAGC
+CGGGGAGGCATCAGCCAGCGCGGCGTCGGCTGACACAGCCAGAACGGCGGCAGCCGCCTC
+GTCATCAGCATCGTAGGCATCCACCCACGCCGCCGCATCTGATACCAGCGCATCACTGGC
+AGCGCAAAGCAGAGCTGCAGCCGGAGAATCGGCAACCAGAGCCGAAGAGGCCGCGAAACG
+GGCCGAGGATATCGCAGACGTGATTTCCCTGGAAGATGCAAGCCTGACGAAAAAAGGTAT
+CGTTAAATTAAGCAGTGCCACGGACAGTGACAGCGAAGCGCTGGCGGCCACACCAAAGGC
+GGTAAAAACCGTTATGGGTGAGGTACGGACCAAAGCGCCGCTGGACAGCCCGGCATTCAC
+TGGAACGCCGACCACACCGACGCCGCCAGGCGATGCTAAAGGGCTTCAGACAACAAACGC
+GGAGTTTGTCCGCAAACTGATTGCCGCGCTGGTTGGTTCCGTACTGGAGCCACTGGACAC
+CCTGCAGGAACTGGCTGACGCGTTGGGAAATGATCCGAACTTTGCCACCACGGTACTGAA
+TAAACTGGCGGGCAAGCAGCCGCTGGACGAAACCCTGACGGCGCTGTCAGGAAAAAGCGT
+TGACGGTCTTATCGAATACGTTGGTTTGCGAGAAACCATAAGTCGTGCCGCCGATGCATT
+ACAAAAATCACAGAATGGCGGCGATATTCCGGACAAGGATTTGTTTGTGCGTCGTATCGG
+TGCCGCGCGAGCGTTTGATGGCGCAGTTATTATCGGCTGTGATGATAATCCGTGGACGAC
+GGCGGAGTTTATCGTCTGGCTGGAGTCTCAGGGCGCATTCAATCACCCTTACTGGATGTG
+TCGTGGCTCCTGGTCTTACGCTTATAACAAAATCATCACGGATACTGGCTGCGGTAATAT
+CTGTCTCGCTGGCGCAGTGATTGAGGTAATGGGAGTGCGTGGCGCGATGACTATTCGGGT
+GACAACGTCCCATTCAGTATCTGGTTGGTGATACGTGGGTGACAGCCCCAAGTGTATAAG
+AAGGAATAATTATGACAGCGGAAAAAAAATAAAAAGAACAAACAGTTTTTAAATATTAAA
+AATTTCATTCCGTATGCACCGGAACCAGATGACACATTATTCGCCGATGCGGCGTATCTT
+AAATCAGAGGATGGTCAGGACTGGTATGGGTGCCAGCAATTATTTTCAGCAGACACGCTG
+AAAATTACCTACGACGATAACGATGTTATTACGTGTATTACGCGTGATGTTTCCGGGCTG
+TGGCCTGCTGGCCAGAGCGTTGCAGAGTTGCCTGATACGGATGAAAACCGTCGCGCTGAT
+ATTCATGCTGCTGGCAGTTTAAAGACGGTAAAGTCGTTCAAAGGGTTTATTCGCCGGAAG
+AGCTGCGCAGGCAGGCAGAATCGAAAATTGAACGCCCGGGCGTTGATACCGGATGATCTG
+GTCATCGTGGAAAGCGACCCTGAAAAAATCGACACTTTAGCTGTAAAATGACAGTCCCGC
+CATCCGGTCATCATAACGGATTTTTCTTCTGCACCTTCTGAAGCCCGCCATGTCAGGACG
+ACCATGAATCCGCCGATAACCTTATTGTGAAATTAAGACCAGGAAGAGATGATGTCTGCC
+GGACAGATACTATATGTAAATTTATAAAGGTTTTTTGTTATGCCCTTTCATATTGGAAGC
+GGATGTCTTCCCGCCACCATCAGTAATCGCCGCATTTATCGTATTGCCTGGTCTGATACC
+CCCCCTGAAATGAGTTCCTGGGAAAAAATGAAGGAATTTTTTTGCTCAACGCACCAGACT
+GAAGCGCTGGAGTGCATCTGGACGATTTGTCACCCGCCGGCCGGAACGACGCGGGAGGAT
+GTGATCAACAGATTTGAACTGCTCAGGACGCTCGCGTATGCCGGATGGGAGGAAAGCATT
+CATTCCGGCCAGCACGGGGAAAATTACTTCTGTATTCTGGATGAAGACAGTCAGGAGATA
+TTGTCAGTCACCCTTGATGATGCCGGGAACTATACCGTAAATTGCCAGGGGTACAGTGAA
+ACACATCGCCTCACCCTGGACACAGCACAGGGTGAGGAGGGCACAGGACACGCGGAAGGG
+GCATCCGGGACATTCAGGACATCCTTCCTCCCTGCCACAACGGCTCCACAGACGCCAGCA
+GAGTATGATGCTGTCTGGTCAGCGTGGAGAAGGGCTGCACCCGCAGAAGAGTCACGCGGC
+CGTGCAGCAGCGGTACAGAAAATGCGTGCCTGCCTGAATAATGGCAATGCAGTGCTTAAC
+GTGGGAGAATCAGGTCTTACCACCTTGCCAGACTGTTTACCCGCGCATATTACCACACTG
+GTTATTCCTGATAATAATCTGACCAGCCTGCCGGCGCTGCCGCCAGAACTGCGGACGCTG
+GAGGTCTCTGGTAACCAGCTGACTAGCCTGCCGGTGCTGCCGCCAGGACTACTGGAACTG
+TCGATCTTTAGTAACCCGCTGACCCACCTGCCGGCGCTGCCGTCAGGACTATGTAAGCTG
+TGGATCTTTGGTAATCAACTGACCAGCCTGCCGGTGTTGCCGCCAGGGCTACAGGAGCTG
+TCGGTATCTGATAACCAACTGGCCAGCCTGCCGGCGCTGCCGTCAGAATTATGTAAGCTG
+TGGGCCTATAATAACCAGCTGACCAGCCTGCCGACGTTGCCGTCAGGGCTACAGGAGCTG
+TCGGTATCTGATAACCAACTGGCCAGCTTGCCGACGCTGCCGTCAGAATTATATAAGCTG
+TGGGCCTATAATAATCGGCTGACCAGCCTGCCGGCGTTGCCGTCAGGACTGAAGGAGCTG
+ATTGTATCTGGTAACCGGCTGACCAGTCTGCCGGTGCTGCCGTCAGAACTGAAGGAGCTG
+ATGGTATCTGGTAACCGGCTGACCAGCCTGCCGATGCTGCCGTCAGGACTACTGTCGCTG
+TCGGTCTATCGTAACCAGCTGACCCGCCTGCCGGAAAGTCTCATTCATCTGTCTTCAGAG
+ACAACCGTAAATCTGGAAGGGAACCCACTGTCTGAACGTACTTTGCAGGCGCTGCGGGAG
+ATCACCAGCGCGCCTGGCTATTCAGGCCCCATAATACGATTCGATATGGCGGGAGCCTCC
+GCCCCCCGGGAAACTCGGGCACTGCACCTGGCGGCCGCTGACTGGCTGGTGCCTGCCCGG
+GAGGGGGAACCGGCTCCTGCAGACAGATGGCATATGTTCGGACAGGAAGATAACGCCGAC
+GCCTTCAGCCTCTTCCTGGACAGACTGAGTGAGACGGAAAACTTCATAAAGGACGCGGGG
+TTTAAGGCACAGATATCGTCCTGGCTGGCACAACTGGCTGAAGATGAGGCGTTGAGAGCA
+AACACCTTTGCTATGGCAACAGAGGCAACCTCAAGCTGCGAGGACCGGGTCACATTTTTT
+TTGCACCAGATGAAGAACGTACAGCTGGTACATAATGCAGAAAAAGGGCAATACGATAAC
+GATCTCGCGGCGCTGGTTGCCACGGGGCGTGAGATGTTCCGTCTGGGAAAACTGGAACAG
+ATTGCCCGGGAAAAGGTCAGAACGCTGGCTCTCGTTGATGAAATTGAGGTCTGGCTGGCG
+TATCAGAATAAGCTGAAGAAATCACTCGGGCTGACCAGCGTGACGTCAGAAATGCGTTTC
+TTTGACGTATCCGGCGTGACGGTTACAGACCTTCAGGACGCGGAGCTTCAGGTGAAAGCC
+GCTGAAAAAAGCGAGTTCAGGGAGTGGATACTGCAGTGGGGGCCGTTACACAGAGTGCTG
+GAGCGCAAAGCGCCGAAACGCGTTAACGCGCTTCGTGAAAAGCAAATATCGGATTATGAG
+GAAACGTACCGGATGCTGTCTGACACAGAGCTGAGACCGTCTGGGCTGGTCGGTAATACC
+GATGCAGAGCGCACTATCGGAGCAAGAGCGATGGAGAGCGCGAAAAAGACATTTTTGGAT
+GGCCTGCGACCTCTTGTGGAGGAGATGCTGGGGAGCTATCTGAACGTTCAGTGGCGTCGT
+AACTGATGCACCAGGTGAATGAGGTGCGGTGCGACAAAGATATTCCCGGACGAACAACAT
+CAGACAGTACGGATGATGTACAGGTGAAATAGGGGAGACTTCTTCAGTCAGGGCGCGGCG
+CAACTTTTTCGATGATAACGCGCCGCGCGCCGGTAGCGAGAAGCCGATGGAAGTACTGGA
+TCACCTGAATGCAAAGAAGGGCAGGGGAAAGCTGTACTTTGCCGGGGAGGGTATCCAGCA
+ACAGTGGGCTATGAAGAGAAACATACTGTCATCCCGATATACCACCCGCTATGAAGACCT
+GCTTCAGGTTAAGTGACAGGTTTACCCTGATTTTCAAATTTCTGATGTGATGGTGTGCCG
+CAGCCACATTGTATGCAAGAACGGGCTGCGGCAAACTGGCGATCGTTCGATAGTGCGTGT
+ATTGAATAGTTACCAGTCGTGGCGGATTCTACTGGTTAAGGATGACTAATCAATGTATTT
+AAGTCATCTGTTCAACTTTTCGCGTTGGAGGGAGCTTGAAGTCAATTTGCAGTGACCTTC
+GATAGCTATTTCACCATCATTTCACCATTTGCAAATTGGATATATAAAAAAACCAGCCCT
+GGCAGGCTGGCTTTTAAGGGGAATTTTGGTCGGCACGAGAGGATTTGAACCTCCGACCCC
+CGACACCCCATGACGGTGCGCTACCAGGCTGCGCTACGTGCCGACTTGTGGGTGCTAATA
+CTACCTCTTTCCAACGCGAATGCAAGGGGAAACGGTGCTAACTGATTTATAATTAATCAG
+TTAGCGATAAAACGTTTCTCTTCTGTTAGCACTTGCAGCAGCAGACTGAGCTGCGGCTTC
+TGATCTTTGATCTTCTCGCCGTGTAAGTCATAGGTCTGATAATGACCGTTATTATTGAGC
+ACCAGGGTCATTTGCGGCGTCGTGATTGCCAGCGTACTGCCGTCTGCCGCCGTTACCCAG
+TTATGACGACGTGGAACGGTAAAGATGTCCTGGCCCTGTGAATATTCGTTCGCTGGCGTG
+CTGACATGTAACAGGCGTTGCATCAACGTGGTCATCACATCGGTATGATCGGTAAGCACA
+TTAATACGCTGCGCAGGCGTCCCCGGCCAGTGGATCACCAGCGGTACTTGCAGATGACCT
+TGCGACCAGTCGAAGCGATTTTCTTCCGGCGTCAACGGTATGCCGCGTCCTGCGGTAATG
+ATCACGACAGTATTGTCGAATTTACCGGCCTCTCGCAGCGCGTTCAGAACCCGATTGATT
+TGCGCATCCACGTCGCTGGCGGCACTGGCGTAACGCTTAACAAAATTTTTCTGGTTACTG
+TCATCAATGTTAGTACCGTTAAACGATATCCATGAGAACCAGCGGTTATCTTCCTGTGCG
+TAGCGCCCAAGCCAGTCTATCCACTGGCTGGCCGTTTGCGCATCAGACTGCGTTTGCGCT
+GCCGGCATCGAGAAATCGGACAGTAATGCCTGACGATAAAGCGGGCTGGCGAAGCCATCC
+GAAGAAAACAGTCCCAGTTGGTAGCCTTGCTGATTCAACGCGGTAATGAGCGCCGCAGGC
+GTTCTGGTGGATAACACGCCATCCATATAGCCTGGCGATATGCCATAGAACAGGCCGAAA
+ATACCGTTATCAGTGGTATTCCCTGAACTCATATGACGGGTGAAGTCGATGTTTTGCTCG
+GCAAATGTAGCCAGCTCCGGCATCTGCTTCTCAAAGCGAGAATAGTTCAGGCCGTCTACG
+GTAATGAGCAGCACATTCTGACCGGTGCCCATATCGCGATAGTGCAAATTGCTGAGCGGG
+TACTGAACGGAGACCGCTTCCGGATTGCCTTGCTCTACCAGACGGCGCTGATATTCCTGC
+GCATCCAGCAGACCGTGTTTTTCAAGAAAACGTCGCGCCGTCATCGGATAAGAGAGCGGC
+AGGTTTGCCCGCTGCATGGTAATCGGCCGGTAAAAATTAGCGTCTGCCCAGATGTAGATA
+AGATGCGATGCGATAAAGGAGACGAAAAAGAATGCCGCAAGCGGCCTTGCGAAATGGCGG
+CGGCGCGTGAGACTGCGCAGCTTTTGCCAACTCCATGTCGCAAATAGCATCTCAATCAAT
+AAGATAACTGGCACGCTAATAAACATAAGCTGCCAGTCGCGCGCCATTTCGTTCTGGTCA
+GGGTTGATGACCAGTTCCCAGACAATGGGGTTAAGATGCAGGTGAAAACGGGTAAAGACT
+TCGCTGTCGATAAGCAACAACGTCATACCCGCGGTCGCCAGAATGGCTGATAAAAACCGC
+ATCAGCCGCTGGGACATCACGATAAACGTGAGCGGAAAAAGAATAAGCAAATAGGTGGCG
+AACACCAGAAAGCTAAAGTGCCCGACAATGCTCAGGTAGGAGTATATGCGACCCGCAAGC
+GTTGTCGGCCAGTCGGCGACAAACAGGTAACGGCTGCCGAGCAACGTAGCCAACAGTATA
+TTGAACAGAGCGAACCAGTGCCCCCAGCTAACCATCTGGGAGACTTTTTCACGGTAGCGC
+TGACGATGAGTTACCATACCTGTCGCTTGTTTCTCCGGAGTCGGCTTTTTAGTGCGCGTT
+GTCTTCGCTAATCGAAGACTGCAAGGCGCGGGCAAAAGAGTTCGCAATCGCCTGGCGTTG
+AGCCGGCGCCACGCTGGTGTTGATAAGGTTGGTGACCATATTTCCCAGTACCATCAGGGA
+AAGATCGGTCGGCGCCTTATGTTTTTCCAGTACACTGAGCAGTTCGCTCAGCAGTTGTTC
+AACATGTTCATCACTATAGCGGGAGAGTTGTGGCATAAATCAAAATCTGTTTGTTCATGA
+AAGGGCAACATATTACCGTAGCAACAGTTTTTTTTCTGCATTTTTATCCCCTAAATCATT
+CGCGTTACGGATAACGCCTGAAATGACAGGGCGATTGCTTGCGTCTTCCGGCAGGCGGTG
+GTTGAATACCGCCCGGTCTTAAAGGAGAGTTTATCATGAGTCTGGATATCAACCAGATTG
+CCCTGCACCAGCTTATCAAGCGCGATGAGCAAAATCTTGAGCTGGTCTTGCGCGATTCAT
+TGCTGGAGCCGACAACCACCGTTGTCGAGATGGTGGCTGAACTGCATCGGGTCTATAGCG
+CCAAGAATAAGGCGTATGGCCTGTTTAATGAAGAGAGTGAACTGGCGCAAGCGCTGCGGT
+TGCAACGTCAGGGGGAAGAAGATTTTCTTGCCTTTAGCCGGGCGGCGACCGGACGCCTGC
+GTGACGAACTGGCGAAATATCCCTTTGCGGACGGCGGCATTGTATTGTTCTGCCATTATC
+GTTACCTGGCGGTGGAGTATCTGCTGGTTACGGTACTGAACAACCTGAGCAGTATGCGGG
+TCAATGAAAATCTGGACATTAACCCGACGCATTATCTTGATATCAACCATGCGGATATCG
+TGGCGCGTATCGATCTTACCGAGTGGGAAACTAATCCGCAATCGACCCGCTACCTGACGT
+TCCTGAAAGGTCGGGTAGGGCGCAAGGTCGCTGACTTCTTTATGGATTTCCTCGGCGCCA
+GCGAAGGGTTGAACGCCAAAGCGCAGAATCGCGGCCTGTTGCAGGCAGTGGATGATTTCA
+CCGCAGAAGCGCAGTTGGATAAAGCAGAACGTCAGAACGTGCGTCAGCAGGTGTACAGCT
+ACTGCAACGAGCAGTTACAAGCCGGGGAAGAGATTGAGCTGGAATCGCTGTCTAAAGAGC
+TTTCCGGCGTCAGTGAAGTCAGCTTCAGCGAATTTACCGCCGAAAAAGGCTATGAGCTGG
+AAGAGAGCTTCCCGGCAGATCGCAGTACGCTACGCCAGTTAACCAAATATGCCGGCAGCG
+GCGGCGGGTTAACGATTAACTTTGATGCGATGCTACTGGGCGAGCGGATTTTCTGGGACC
+CGGCGACCGATACCCTGACTATCAAAGGGACGCCGCCGAATTTGCGCGATCAGTTGCAGC
+GACGCACGTCGGGCGGGAAATAAAGGCATACGACATAAAAGGACGCCGTAGTGAGTAAAG
+GAATACGTCAGAGGCCGCCTGTTAATTTCAGTTTATTTCGGCAGGTTTTGTATGCGCACA
+TTGTCGCATTTTTGATGATGTTGATGCTCGGCATGGTGTTCACCGTTCTCTCGTTGGTAC
+TGTTTTATACTTATGGCGCCAACTGGTTACTGAGCTTGTTCATATGCCCGCTGTTCTTGT
+TAAGTGGTTTATTCATTACTGGATTTGCTTTTAAATCAACCTGGTCCAGCATACGTTACT
+ATTACGACAAGGGGCAGTTGAAACGGTATGGACTCAATCTTGATGCAACTTTGACGCATA
+AAGAGAAGGTGGAAATACGCATCGATAATGCAAAGCGTCAAGTGCGTGTAGATGAACTGG
+AACTCCATGTCTTATTTGATTTTCAGTTTGATAGCAAGACATGGAGCTGCGGCGACTTAC
+TGACCAATGAAAAGGTATTTGATGCGTTGAATGATGGGCAAACGATACCAATACGAATTT
+TGCCATGGAAACCGGAAAGTGCCAGCGTTCGTCAACGGGCATTATTCAATCGGCTTAAAG
+GTATGAATACCGCGGCGGAAACTACAGATCCTCGATTAGGGGAGGCGCTAATTGAATGTG
+GCGAGGTGTAAGAAAGCAGAAAAGCAAAGTGGGTTCTCGTTGCTCTGCATGTCGTCAAAT
+TCAATTAAACGCATAAAAAAACCCCGCCGGGGCGGGGTTTTTCTTCAACTTCCAGGCGAT
+TACGCGCGAACGAAGTCGATGTGAGTCAGCTTCGGTTTGTAAGCGTGACGCTGTACAGCC
+TGAGCTTTAACTTTTACTTCTTTACCGTCAACAACGAGGGTCAGAACTTCGCTGTAGAAT
+TCAGCTTTAGCTTGCATGTTCATCACCTGGTCGTGGTCCAGTTCGATAGCAATCGGGGCT
+TCAGAACCGCCGTAGATGATTGCCGGGAACTTGTTAGCGGCGCGCAGGCGGCGGCTCGCA
+CCCTTACCCTGCTCTTTACGTACTTCTGCGTTGATAGTAAACATTTAAATCTCTCTTTAA
+TAATTCCTGCTACAGGCGACCCAGCAACAGGTAAGTGATCTGCTTTGCGTATGCAAAGGC
+GGGCGGGATTCTATACTCAAATCGCCGTTACATCAATGAAAAGTACAATTAACCACGTAA
+TTCGTGCGCCCGGCGGAAGCGGCCTTCATAGTCGAACACTTTTTCACGCACCTGCCAGTA
+CTGGCCTTTCATCCGCGCGACCACAAAATCGGGATGCCGCAACAGCGCCTGCTGCGCGAC
+AATATCCGCCGCCGTGATCCAGCGTAAAGGAACGCCGGGCGTGCGCGTATGCGGGCGAAT
+AAATAGCTGTTCGAAAGCGGTACGCTGGGCGGGCGTGTGCAAGCGGAAGCGCTCACTGAC
+ATCCGCGCCGTCCTCGTCATAGTAAGTGATTTTCAGCCATTCGCCTTTCTCATCCTGCCC
+ATGCTGCATCGTCATTCCGCTACAGCGCAGGACTAACGCATCCTTGAGCCTGAGCGCCGC
+TTTTAACATATCGTCCGGGTCGACCAGAATGGCGTCACATTCCCGGCAGCGTCGGGCGGC
+AATATCGTTTTCGGCATTACACTGCGGGCAGTTTTTGAAGCGAAAGCGAAAATCGCACTG
+CTCGCGATGGCCGTCGTCATCCTCAAACCAGCCCTGGCAGCGACGGCCAAAGTGTTCAAT
+CAGCGTGCCGTCGGCAGTGGTTTTCCCCCAGAAGGTGTTGGCAAAGCCGCAGGCCGGGCA
+AAATACCTGGACAGGGACGTTATCGCTTTTTCCCTTCGGGCTACCGACCTCCGGGGCATA
+CAGGTCGTGCGGGTTGCCTGCGTAATCAAGAATCAGGCAATCGGTCTTTCCCGGCGCAAG
+GCGCAGACCACGCCCGACAATTTGTTGGTAAAGACTAACTGACTCCGTGGGACGTAGAAT
+CGCGATGAGATCAACGTGTGGGGCGTCAAAGCCGGTGGTCAGTACCGAGACGTTAACCAG
+ATAGCGAAAACGCTGCGCCTTGAAATTATCAATCAGCGCGTCGCGCTCGGGCCCTGGCGT
+ATCGCCGGTAATCAGCGCCGCGTCGTCCGCCGGAAGCAGACCGACAATCTCTTTCGCATG
+TTCGACCGTGGCGGCGAAAATCATCACGCCTTTGCGCGTTTGCGCAAATTCCATAATCTG
+GCTGATGATGTGCGGCGTAATCCGCTGCTGCTTTTTCAGCTCGCGGTTCAGGTCGGCTTC
+GCTGAACAGCCCATTGCTTTGGGCCTGCAGGCGGCTGAAATCGTATTGGACCACTGGCAT
+ATCAAGCCGCTCAGGCGGCGTCAGATAGCCGTGTTTAATCATATAGCGCAGCGGCAGTTC
+ATAAATACAGTCGCGAAACAGAGCGTTGTCGTTGCCGCGCACCATACCGTGATAATGAAA
+TTGATAAATCCAGCCTTTTCCGAGGCGAAAAGGCGTGGCGGTGAGTCCAAGCAGACGTAA
+GTGAGGATTAACTTTACTCAGGTGAGTGAGGATTTGCTGATACTGACTGTCTTCATCGTC
+ACCGATGCGGTGGCATTCATCGACAATCAACAGCGAAAACTCCTCCTGGAAGGCGTCAAG
+ATTACGCGCCACCGACTGTACGCTGCCGAACACGACTTTGCCCTGACTCTCTTTACGTTT
+GAGTCCGGCGGCGAAAATATCCGCTTCCAGCCCCAGCGCGCAATATTTGGCGTGGTTCTG
+CGCGACCAGCTCTTTCACATGCGCCAGCACCAGTACCCGTCCGCGGGCGACGCGCGCCAG
+TTCGGCGATCACCAGGCTTTTACCTGCGCCGGTCGGCAGAACAATCACGGCGGGCGTACG
+GTGGCGGCGAAAGTGGCTGAGCGTGGCGTCTACGGCTTCTTGCTGGTAGGGGCGGAGTGT
+AAAAATCATGGTCTCACTACGTTAAACGGTTCCGGGAATAGTATGCCATGAATCATTTCC
+CTTGAGGGATATAGTTAGCCCGCTATACTGAGCGGATAGCAATTCCCTTTTTTCGGGTAG
+AATGCCCGATTTCCGTATTATTACAGGCTAAATCACACACATGCGACTTGATAAATTTAT
+CGCTCAGCAGCTTGGCGTCAGCCGCGCTATTGCCGGGCGTGAAATTCGTGGTAACCGCGT
+TACCGTCGATGGCGACATCATTAAAAATGCGGCCTTCAAACTGCTCCCGGAACATGCGGT
+TGCGTATGACGGCAATCCCTTAGCGCAGCAACACGGGCCACGCTATTTTATGCTTAACAA
+GCCGCAGGGATACGTTTGTTCAACCGATGATCCCGATCATCCAACGGTGCTGTATTTCCT
+GGATGAGCCGGTGGCGTATAAGCTGCATGCCGCAGGACGTCTGGATATCGATACTACCGG
+TCTGGTGTTAATGACAGATGACGGTCAGTGGTCGCACCGCATTACGTCGCCGCGCCATCA
+CTGTGAAAAAACCTATCTGGTGACCCTGGAGTCGCCGGTGGCCGACGATACGGCAGCGCA
+ATTTGCGAAAGGCGTGCAGTTGCATAATGAAAAAGATCTCACTAAACCCGCTACGCTGGA
+GGTGATAACACCTGTGCAGGTCCGTCTGACCATCAGCGAAGGCCGTTATCATCAGGTGAA
+GCGGATGTTTGCCGCAGTAGGCAATCGCGTTGTGGAACTGCACCGCGAACGGATTGGCGC
+CATTACGCTGGATGAGAATCTGGCTCCCGGCGAGTACCGCCCGTTGACTGAAGAAGAAAT
+CGCCAGCGTCGGCTAACTATCTCGTTAAATTCAGGAGTTCGATGTGACCACCCGGCAGCA
+CTCTTCCTTTGCCATTGTCTTTATTCTTGGCCTGTTGGCCATGTTAATGCCGCTGTCGAT
+TGATATGTATCTTCCAGCGCTGCCGGTGATTTCTGCGCAATTCGGCGTGCCTGCCGGTAG
+CGCGCAGATGACGCTCAGCACCTATATTCTGGGGTTTGCGCTGGGTCAGCTTATCTATGG
+ACCGATGGCGGATAGCCTCGGGCGTAAGCCGGTCATCCTGGGCGGGACGCTGGTATTTGC
+CGCTGCGGCGGTCGCCTGTGCGTTGGCGCAGACTATCGATCAACTGATCGTGATGCGTTT
+CTTTCACGGTTTGGTGGCTGCGGCGGCAAGCGTCGTCATCAATGCGCTGATGCGGGATAT
+TTATCCAAAGGAAGAGTTTTCGCGCATGATGTCATTTGTCATGCTGGTCACTACGATAGC
+GCCGTTAATGGCGCCCATTGTTGGCGGCTGGGTGTTGGTATGGTTAAGCTGGCACTATAT
+CTTCTGGATACTGGCTATTGCGGCGATTCTGGCGTCAGTCATGATCTTTGCTTTGATTAA
+AGAGACGCTGCCCGTTGAGCGGCGTCAGCCTTTTCATATTCGTACCACAATAGGTAACTT
+TGCCGCGTTGTTTCGCCACAAACGCGTACTGAGCTATATGCTGGCGAGCGGGTTCAGTTT
+TGCCGGTATGTTCTCTTTTTTGAGCGCGGGGCCGTTTGTCTATATCGAAATTAATCATGT
+TCCGCCGCAGGATTTCGGCTACTACTTCGCGTTGAACATCGTATTTCTGTTTGTGATGAC
+GATTATCAACAGCCGTTTTGTCAGACGGGTAGGGGCGCTAAACATGTTTCGGGCCGGGCT
+ATGGATTCAGTTTGCGATGGCGGTGTGGATGGTTTTCAGCGCGCTGATGGGCATTGGATT
+CTGGGCGCTGGTGGTTGGCGTTGCGGCGTTTGTCGGCTGTGTGTCGATGGTTTCGTCCAA
+TGCGATGGCGGTCATTTTGGATGAGTTTCCGCATATGGCCGGAACGGCGTCTTCGTTGGC
+GGGCACTTTCCGCTTTGGTATTGGCGCTATCGTCGGCGCGTTGCTGTCGCTGGCTACCTT
+TAACAGTGCGTGGCCGATGATCTGGTCGATTGCGCTTTGCGCCGCCTGTTCCATTCTGTT
\ No newline at end of file
diff --git a/t/data/genbank_gbff/genbank3.gff.proteome.faa.expected b/t/data/genbank_gbff/genbank3.gff.proteome.faa.expected
new file mode 100644
index 0000000..0a7d914
--- /dev/null
+++ b/t/data/genbank_gbff/genbank3.gff.proteome.faa.expected
@@ -0,0 +1,26 @@
+>ERS325326_00001.p01
+MPEVTPFQVLIVDDHPLMRRGIRQLLELDPAFYVVAEAGDGASAIDLANRIEPDLILLDL
+NMKGLSGLDTLNALRRDGVTAQIIILTVSDSASDIYALIDAGADGYLLKDSDPEVLLEAI
+RKGANGGKVFSDRVNEYLRERERFGAQEDPFSILTERELDVLHELAQGLSNKQIASVLNI
+SEQTVKVHIRNLLRKLNVRSRVAATILFLQTRGMQ*
+>ERS325326_00003.p01
+VISLEDASLTKKGIVKLSSATDSDSEALAATPKAVKTVMGEVRTKAPLDSPAFTGTPTTP
+TPPGDAKGLQTTNAEFVRKLIAALVGSVLEPLDTLQELADALGNDPNFATTVLNKLAGKQ
+PLDETLTALSGKSVDGLIEYVGLRETISRAADALQKSQNGGDIPDKDLFVRRIGAARAFD
+GAVIIGCDDNPWTTAEFIVWLESQGAFNHPYWMCRGSWSYAYNKIITDTGCGNICLAGAV
+IEVMGVRGAMTIRVTTSHSVSGW*
+>ERS325326_00004.p01
+MPFHIGSGCLPATISNRRIYRIAWSDTPPEMSSWEKMKEFFCSTHQTEALECIWTICHPP
+AGTTREDVINRFELLRTLAYAGWEESIHSGQHGENYFCILDEDSQEILSVTLDDAGNYTV
+NCQGYSETHRLTLDTAQGEEGTGHAEGASGTFRTSFLPATTAPQTPAEYDAVWSAWRRAA
+PAEESRGRAAAVQKMRACLNNGNAVLNVGESGLTTLPDCLPAHITTLVIPDNNLTSLPAL
+PPELRTLEVSGNQLTSLPVLPPGLLELSIFSNPLTHLPALPSGLCKLWIFGNQLTSLPVL
+PPGLQELSVSDNQLASLPALPSELCKLWAYNNQLTSLPTLPSGLQELSVSDNQLASLPTL
+PSELYKLWAYNNRLTSLPALPSGLKELIVSGNRLTSLPVLPSELKELMVSGNRLTSLPML
+PSGLLSLSVYRNQLTRLPESLIHLSSETTVNLEGNPLSERTLQALREITSAPGYSGPIIR
+FDMAGASAPRETRALHLAAADWLVPAREGEPAPADRWHMFGQEDNADAFSLFLDRLSETE
+NFIKDAGFKAQISSWLAQLAEDEALRANTFAMATEATSSCEDRVTFFLHQMKNVQLVHNA
+EKGQYDNDLAALVATGREMFRLGKLEQIAREKVRTLALVDEIEVWLAYQNKLKKSLGLTS
+VTSEMRFFDVSGVTVTDLQDAELQVKAAEKSEFREWILQWGPLHRVLERKAPKRVNALRE
+KQISDYEETYRMLSDTELRPSGLVGNTDAERTIGARAMESAKKTFLDGLRPLVEEMLGSY
+LNVQWRRN*
diff --git a/t/data/genbank_gbff/genbank_gene_presence_absence.csv b/t/data/genbank_gbff/genbank_gene_presence_absence.csv
new file mode 100644
index 0000000..a3e7826
--- /dev/null
+++ b/t/data/genbank_gbff/genbank_gene_presence_absence.csv
@@ -0,0 +1,12 @@
+"Gene","Non-unique Gene name","Annotation","No. isolates","No. sequences","Avg sequences per isolate","Genome Fragment","Order within Fragment","Accessory Fragment","Accessory Order with Fragment","QC","Min group size nuc","Max group size nuc","Avg group size nuc","genbank1","genbank2","genbank3"
+"group_10","","side tail fiber protein","2","2","1","2","3","2","2","","791","791","791","","ERS325340_00003.p01","ERS325326_00003.p01"
+"group_11","","secreted effector protein","2","2","1","2","1","2","1","","2366","2366","2366","","ERS325340_00004.p01","ERS325326_00004.p01"
+"group_9","","transcriptional regulator NarP","2","2","1","2","2","2","3","","647","647","647","","ERS325340_00001.p01","ERS325326_00001.p01"
+"group_1","","2-dehydro-3-deoxyphosphooctonate aldolase","1","1","1","1","1","1","1","","854","854","854","ERS325254_00002.p01","",""
+"group_2","","regulator","1","1","1","1","2","1","8","","809","809","809","ERS325254_00003.p01","",""
+"group_3","","regulator","1","1","1","1","8","1","7","","389","389","389","ERS325254_00004.p01","",""
+"group_4","","N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase","1","1","1","1","7","1","6","","833","833","833","ERS325254_00005.p01","",""
+"group_5","","peptide chain release factor 1 (RF-1)","1","1","1","1","6","1","5","","1082","1082","1082","ERS325254_00006.p01","",""
+"group_6","","glutamyl-tRNA reductase","1","1","1","1","5","1","4","","1256","1256","1256","ERS325254_00007.p01","",""
+"group_7","","outer membrane lipoprotein","1","1","1","1","4","1","3","","623","623","623","ERS325254_00008.p01","",""
+"group_8","","isopentenyl monophosphate kinase","1","1","1","1","3","1","2","","851","851","851","ERS325254_00009.p01","",""
diff --git a/t/data/gene_category_count.csv b/t/data/gene_category_count.csv
new file mode 100644
index 0000000..ef92db9
--- /dev/null
+++ b/t/data/gene_category_count.csv
@@ -0,0 +1 @@
+Gene,Non-unique Gene name,Annotation,No. isolates,No. sequences,Avg sequences per isolate,Genome Fragment,Order within Fragment,Accessory Fragment,Accessory Order with Fragment,QC,"Min group size nuc","Max group size nuc","Avg group size nuc",sample1,sample2,sample3,sample4,sample5,sample6,sample7,sample8,sample9,sample10,sample11,sample12,sample13,sample14,sample15,sample16,sample17,sample18,sample19,sample20,sample21,sample22,sample23,sample24,sample25,sample26,sample27,sample28,sample [...]
bcsC_1,,cellulose synthase subunit BcsC,9,9,1,11,5692,,,,,,,sample1_001,sample2_001,sample3_001,sample4_001,sample5_001,sample6_001,sample7_001,sample8_001,sample9_001,sample10_001,sample11_001,sample12_001,sample13_001,sample14_001,sample15_001,sample16_001,sample17_001,sample18_001,sample19_001,sample20_001,sample21_001,sample22_001,sample23_001,sample24_001,sample25_001,sample26_001,sample27_001,sample28_001,sample29_001,sample30_001
betC_2,,sulfatase,9,9,1,11,1876,,,,,,,,sample2_002,sample3_002,sample4_002,sample5_002,sample6_002,sample7_002,sample8_002,sample9_002,sample10_002,sample11_002,sample12_002,sample13_002,sample14_002,sample15_002,sample16_002,sample17_002,sample18_002,sample19_002,sample20_002,sample21_002,sample22_002,sample23_002,sample24_002,sample25_002,sample26_002,sample27_002,sample28_002,sample29_002,sample30_002
comM_2,,putative ATP-dependent protease,9,9,1,11,6422,,,,,,,,,sample3_003,sample4_003,sample5_003,sample6_003,sample7_003,sample8_003,sample9_003,sample10_003,sample11_003,sample12_003,sample13_003,sample14_003,sample15_003,sample16_003,sample17_003,sample18_003,sample19_003,sample20_003,sample21_003,sample22_003,sample23_003,sample24_003,sample25_003,sample26_003,sample27_003,sample28_003,sample29_003,sample30_003
dmsA4_1,,anaerobic dimethyl sulfoxide reductase subunit A,9,9,1,11,540,,,,,,,,,,sample4_004,sample5_004,sample6_004,sample7_004,sample8_004,sample9_004,sample10_004,sample11_004,sample12_004,sample13_004,sample14_004,sample15_004,sample16_004,sample17_004,sample18_004,sample19_004,sample20_004,sample21_004,sample22_004,sample23_004,sample24_004,sample25_004,sample26_004,sample27_004,sample28_004,sample29_004,sample30_004
dosC,,diguanylate cylase,9,9,1,11,909,,,,,,,,,,,sample5_005,sample6_005,sample7_005,sample8_005,sample9_005,sample10_005,sample11_005,sample12_005,sample13_005,sample14_005,sample15_005,sample16_005,sample17_005,sample18_005,sample19_005,sample20_005,sample21_005,sample22_005,sample23_005,sample24_005,sample25_005,sample26_005,sample27_005,sample28_005,sample29_005,sample30_005
dsbA_3,,Thiol:disulfide interchange protein,9,9,1,11,1676,,,,,,,,,,,,sample6_006,sample7_006,sample8_006,sample9_006,sample10_006,sample11_006,sample12_006,sample13_006,sample14_006,sample15_006,sample16_006,sample17_006,sample18_006,sample19_006,sample20_006,sample21_006,sample22_006,sample23_006,sample24_006,sample25_006,sample26_006,sample27_006,sample28_006,sample29_006,sample30_006
fadH_1,,2 4-dienoyl-CoA reductase,9,9,1,11,5287,,,,,,,,,,,,,sample7_007,sample8_007,sample9_007,sample10_007,sample11_007,sample12_007,sample13_007,sample14_007,sample15_007,sample16_007,sample17_007,sample18_007,sample19_007,sample20_007,sample21_007,sample22_007,sample23_007,sample24_007,sample25_007,sample26_007,sample27_007,sample28_007,sample29_007,sample30_007
fimD_3,,outer membrane usher protein FimD,9,9,1,11,1813,,,,,,,,,,,,,,sample8_008,sample9_008,sample10_008,sample11_008,sample12_008,sample13_008,sample14_008,sample15_008,sample16_008,sample17_008,sample18_008,sample19_008,sample20_008,sample21_008,sample22_008,sample23_008,sample24_008,sample25_008,sample26_008,sample27_008,sample28_008,sample29_008,sample30_008
fliB_2,,lysine-N-methylase,9,9,1,11,1159,,,,,,,,,,,,,,,sample9_009,sample10_009,sample11_009,sample12_009,sample13_009,sample14_009,sample15_009,sample16_009,sample17_009,sample18_009,sample19_009,sample20_009,sample21_009,sample22_009,sample23_009,sample24_009,sample25_009,sample26_009,sample27_009,sample28_009,sample29_009,sample30_009
fliF,,flagellar MS-ring protein,9,9,1,11,1176,,,,,,,,,,,,,,,,sample10_010,sample11_010,sample12_010,sample13_010,sample14_010,sample15_010,sample16_010,sample17_010,sample18_010,sample19_010,sample20_010,sample21_010,sample22_010,sample23_010,sample24_010,sample25_010,sample26_010,sample27_010,sample28_010,sample29_010,sample30_010
ftsN,,cell division protein FtsN,9,9,1,11,6144,,,,,,,,,,,,,,,,,sample11_011,sample12_011,sample13_011,sample14_011,sample15_011,sample16_011,sample17_011,sample18_011,sample19_011,sample20_011,sample21_011,sample22_011,sample23_011,sample24_011,sample25_011,sample26_011,sample27_011,sample28_011,sample29_011,sample30_011
gatY_1,,fructose-bisphosphate aldolase,9,9,1,11,5872,,,,,,,,,,,,,,,,,,sample12_012,sample13_012,sample14_012,sample15_012,sample16_012,sample17_012,sample18_012,sample19_012,sample20_012,sample21_012,sample22_012,sample23_012,sample24_012,sample25_012,sample26_012,sample27_012,sample28_012,sample29_012,sample30_012
glfT2,,glycosyltransferase cell wall biogenesis,9,9,1,11,4176,,,,,,,,,,,,,,,,,,,sample13_013,sample14_013,sample15_013,sample16_013,sample17_013,sample18_013,sample19_013,sample20_013,sample21_013,sample22_013,sample23_013,sample24_013,sample25_013,sample26_013,sample27_013,sample28_013,sample29_013,sample30_013
group_1000,,membrane protein,9,9,1,11,593,,,,,,,,,,,,,,,,,,,,sample14_014,sample15_014,sample16_014,sample17_014,sample18_014,sample19_014,sample20_014,sample21_014,sample22_014,sample23_014,sample24_014,sample25_014,sample26_014,sample27_014,sample28_014,sample29_014,sample30_014
group_1001,,lipoprotein,9,9,1,11,597,,,,,,,,,,,,,,,,,,,,,sample15_015,sample16_015,sample17_015,sample18_015,sample19_015,sample20_015,sample21_015,sample22_015,sample23_015,sample24_015,sample25_015,sample26_015,sample27_015,sample28_015,sample29_015,sample30_015
group_1004,,arylsulfate sulfotransferase,9,9,1,11,2834,,,,,,,,,,,,,,,,,,,,,,sample16_016,sample17_016,sample18_016,sample19_016,sample20_016,sample21_016,sample22_016,sample23_016,sample24_016,sample25_016,sample26_016,sample27_016,sample28_016,sample29_016,sample30_016
group_1006,,putative inner membrane protein,9,9,1,11,2791,,,,,,,,,,,,,,,,,,,,,,,sample17_017,sample18_017,sample19_017,sample20_017,sample21_017,sample22_017,sample23_017,sample24_017,sample25_017,sample26_017,sample27_017,sample28_017,sample29_017,sample30_017
group_1009,,Phage-like protein,9,9,1,11,6416,,,,,,,,,,,,,,,,,,,,,,,,sample18_018,sample19_018,sample20_018,sample21_018,sample22_018,sample23_018,sample24_018,sample25_018,sample26_018,sample27_018,sample28_018,sample29_018,sample30_018
group_220,,putative glycosyl transferase,9,9,1,11,4174,,,,,,,,,,,,,,,,,,,,,,,,,sample19_019,sample20_019,sample21_019,sample22_019,sample23_019,sample24_019,sample25_019,sample26_019,sample27_019,sample28_019,sample29_019,sample30_019
group_277,,arylsulfate sulfotransferase,9,9,1,11,6149,,,,,,,,,,,,,,,,,,,,,,,,,,sample20_020,sample21_020,sample22_020,sample23_020,sample24_020,sample25_020,sample26_020,sample27_020,sample28_020,sample29_020,sample30_020
group_281,,transport system periplasmic binding protein,9,9,1,11,6046,,,,,,,,,,,,,,,,,,,,,,,,,,,sample21_021,sample22_021,sample23_021,sample24_021,sample25_021,sample26_021,sample27_021,sample28_021,sample29_021,sample30_021
group_283,,periplasmic protein,9,9,1,11,6091,,,,,,,,,,,,,,,,,,,,,,,,,,,,sample22_022,sample23_022,sample24_022,sample25_022,sample26_022,sample27_022,sample28_022,sample29_022,sample30_022
group_284,hemN_2,coproporphyrinogen III oxidase,9,9,1,11,6093,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sample23_023,sample24_023,sample25_023,sample26_023,sample27_023,sample28_023,sample29_023,sample30_023
group_288,,permease,9,9,1,11,5969,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sample24_024,sample25_024,sample26_024,sample27_024,sample28_024,sample29_024,sample30_024
hemD,,uroporphyrinogen III synthase,9,9,1,11,2788,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sample25_025,sample26_025,sample27_025,sample28_025,sample29_025,sample30_025
hsrA_2,,Inner membrane transport protein YieO,9,9,1,11,5993,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sample26_026,sample27_026,sample28_026,sample29_026,sample30_026
icsA,,autotransporter MisL,9,9,1,11,5845,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sample27_027,sample28_027,sample29_027,sample30_027
kdpD,,sensor protein KdpD,9,9,1,11,4196,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sample28_028,sample29_028,sample30_028
ligB_1,,NAD-dependent DNA ligase LigB,9,9,1,11,5819,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sample29_029,sample30_029
marT_1,,putative transcriptional regulator MarT,9,9,1,11,5849,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,sample30_030
,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
\ No newline at end of file
diff --git a/t/data/group_1.fa.aln b/t/data/group_1.fa.aln
new file mode 100644
index 0000000..6f6e678
--- /dev/null
+++ b/t/data/group_1.fa.aln
@@ -0,0 +1,84 @@
+>abc_00004
+ATGAGTAAGAACATCACGAAAAATATAATTTTAACGACAACATTATTACTATTAGGTACT
+GTATTACCTCAAAATCAAAAACCAGTATTTAGTTTTTACTCTGAAGCTAAAGCTTATAGC
+ATTGGTCAAGATGAAACTAACATCAATGAATTAATTAAATATTACACACAGCCTCATTTT
+TCATTTTCAAATAAATGGCTATATCAATATGATAATGGAAACATTTATGTTGAACTTAAG
+AGATATTCATGGTCAGCACATATATCTTTATGGGGCGCTGAAAGTTGGGGAAATATTAAT
+CAGTTAAAAGATCGTTACGTAGATGTGTTTGGACTAAAAGACAAAGATACTGATCAGTTA
+TGGTGGTCTTATAGAGAGACATTTACAGGTGGCGTTACACCAGCCGCAAAACCTTCTGAT
+AAAACTTATAATCTTTTTGTGCAATACAAAGATAAACTACAAACGATTATTGGTGCGCAT
+AAAATATACCAAGGCAATAAACCAGTATTAACATTGAAAGAAATCGATTTCCGTGCACGA
+GAAGCGTTAATAAAAAATAAAATATTATATACCGAAAATCGTAATAAAGGTAAGCTTAAG
+ATCACCGGTGGCGGTAATAACTACACTATTGATTTAAGCAAAAGATTACATTCAGATCTA
+GCAAATGTTTATGTTAAAAATCCTAATAAAATAACTGTTGACGTC---CTC------TTT
+GATTAG
+>abc_00004
+ATGAGTAAGAACATCACGAAAAATATAATTTTAACGACAACATTATTACTATTAGGTACT
+GTATTACCTCAAAATCAAAAACCAGTATTTAGTTTTTACTCTGAAGCTAAAGCTTATAGC
+ATTGGTCAAGATGAAACTAACATCAATGAATTAATTAAATATTACACACAGCCTCATTTT
+TCATTTTCAAATAAATGGCTATATCAATATGATAATGGAAACATTTATGTTGAACTTAAG
+AGATATTCATGGTCAGCACATATATCTTTATGGGGCGCTGAAAGTTGGGGAAATATTAAT
+CAGTTAAAAGATCGTTACGTAGATGTGTTTGGACTAAAAGACAAAGATACTGATCAGTTA
+TGGTGGTCTTATAGAGAGACATTTACAGGTGGCGTTACACCAGCCGCAAAACCTTCTGAT
+AAAACTTATAATCTTTTTGTGCAATACAAAGATAAACTACAAACGATTATTGGTGCGCAT
+AAAATATACCAAGGCAATAAACCAGTATTAACATTGAAAGAAATCGATTTCCGTGCACGA
+GAAGCGTTAATAAAAAATAAAATATTATATACCGAAAATCGTAATAAAGGTAAGCTTAAG
+ATCACCGGTGGCGGTAATAACTACACTATTGATTTAAGCAAAAGATTACATTCAGATCTA
+GCAAATGTTTATGTTAAAAATCCTAATAAAATAACTGTTGACGTC---CTC------TTT
+GATTAG
+>abc_00004
+ATGAGTAAGAACATCACGAAAAATATAATTTTAACGACAACATTATTACTATTAGGTACT
+GTATTACCTCAAAATCAAAAACCAGTATTTAGTTTTTACTCTGAAGCTAAAGCTTATAGC
+ATTGGTCAAGATGAAACTAACATCAATGAATTAATTAAATATTACACACAGCCTCATTTT
+TCATTTTCAAATAAATGGCTATATCAATATGATAATGGAAACATTTATGTTGAACTTAAG
+AGATATTCATGGTCAGCACATATATCTTTATGGGGCGCTGAAAGTTGGGGAAATATTAAT
+CAGTTAAAAGATCGTTACGTAGATGTGTTTGGACTAAAAGACAAAGATACTGATCAGTTA
+TGGTGGTCTTATAGAGAGACATTTACAGGTGGCGTTACACCAGCCGCAAAACCTTCTGAT
+AAAACTTATAATCTTTTTGTGCAATACAAAGATAAACTACAAACGATTATTGGTGCGCAT
+AAAATATACCAAGGCAATAAACCAGTATTAACATTGAAAGAAATCGATTTCCGTGCACGA
+GAAGCGTTAATAAAAAATAAAATATTATATACCGAAAATCGTAATAAAGGTAAGCTTAAG
+ATCACCGGTGGCGGTAATAACTACACTATTGATTTAAGCAAAAGATTACATTCAGATCTA
+GCAAATGTTTATGTTAAAAATCCTAATAAAATAACTGTTGACGTC---CTC------TTT
+GATTAG
+>abc_00006
+ATGAAAAAGAACATCATGAATAAATTAGTTTTATCAACAGCATTGTTACTTTTAGGAACC
+ACATCAACACAACTTCCTAAAACACCAATCAGTTTTTCATCTGAAGCAAAAGCCTATAAT
+ATCAGTGAAAACGAGACTAATATCAATGAGTTAATCAAATATTACACTCAGCCGCATTTT
+TCATTATCTGGAAAATGGCTATGGCAAAAGCCCAATGGTAGCATTCATGCAACATTGCAA
+ACGTGGGTTTGGTATAGTCATATTCAAGTGTTTGGATCCGAGAGTTGGGGAAACATTAAT
+CAGTTAAGAAATAAATACGTTGATATATTTGGAACTAAAGATGAGGACACAGTTGAAGGT
+TACTGGACTTATGATGAAACATTTACTGGTGGTGTTACGCCAGCAGCTACTTCATCTGAT
+AAACCTTATAGACTATTTTTAAAATATAGTGATAAACAACAAACTATCATCGGTGGACAT
+GAATTTTACAAAGGAAATAAACCAGTATTAACTTTAAAAGAATTAGATTTCCGTATTCGT
+CAAACATTAATAAAGAATAAAAAGTTATATAACGGAGAATTTAATAAAGGTCAAATTAAG
+ATAACTGCTGATGGAAATAATTACACGATTGATTTAAGTAAAAAGTTAAAATTAACTGAC
+ACAAACCGTTATGTTAAAAATCCTAAAAATGCACAAATTGAAGTCATACTCGAAAAATCT
+AACTAA
+>abc_00006
+ATGAAAAAGAACATCATGAATAAATTAGTTTTATCAACAGCATTGTTACTTTTAGGAACC
+ACATCAACACAACTTCCTAAAACACCAATCAGTTTTTCATCTGAAGCAAAAGCCTATAAT
+ATCAGTGAAAACGAGACTAATATCAATGAGTTAATCAAATATTACACTCAGCCGCATTTT
+TCATTATCTGGAAAATGGCTATGGCAAAAGCCCAATGGTAGCATTCATGCAACATTGCAA
+ACGTGGGTTTGGTATAGTCATATTCAAGTGTTTGGATCCGAGAGTTGGGGAAACATTAAT
+CAGTTAAGAAATAAATACGTTGATATATTTGGAACTAAAGATGAGGACACAGTTGAAGGT
+TACTGGACTTATGATGAAACATTTACTGGTGGTGTTACGCCAGCAGCTACTTCATCTGAT
+AAACCTTATAGACTATTTTTAAAATATAGTGATAAACAACAAACTATCATCGGTGGACAT
+GAATTTTACAAAGGAAATAAACCAGTATTAACTTTAAAAGAATTAGATTTCCGTATTCGT
+CAAACATTAATAAAGAATAAAAAGTTATATAACGGAGAATTTAATAAAGGTCAAATTAAG
+ATAACTGCTGATGGAAATAATTACACGATTGATTTAAGTAAAAAGTTAAAATTAACTGAC
+ACAAACCGTTATGTTAAAAATCCTAAAAATGCACAAATTGAAGTCATACTCGAAAAATCT
+AACTAA
+>abc_00006
+ATGAAAAAGAACATCATGAATAAATTAGTTTTATCAACAGCATTGTTACTTTTAGGAACC
+ACATCAACACAACTTCCTAAAACACCAATCAGTTTTTCATCTGAAGCAAAAGCCTATAAT
+ATCAGTGAAAACGAGACTAATATCAATGAGTTAATCAAATATTACACTCAGCCGCATTTT
+TCATTATCTGGAAAATGGCTATGGCAAAAGCCCAATGGTAGCATTCATGCAACATTGCAA
+ACGTGGGTTTGGTATAGTCATATTCAAGTGTTTGGATCCGAGAGTTGGGGAAACATTAAT
+CAGTTAAGAAATAAATACGTTGATATATTTGGAACTAAAGATGAGGACACAGTTGAAGGT
+TACTGGACTTATGATGAAACATTTACTGGTGGTGTTACGCCAGCAGCTACTTCATCTGAT
+AAACCTTATAGACTATTTTTAAAATATAGTGATAAACAACAAACTATCATCGGTGGACAT
+GAATTTTACAAAGGAAATAAACCAGTATTAACTTTAAAAGAATTAGATTTCCGTATTCGT
+CAAACATTAATAAAGAATAAAAAGTTATATAACGGAGAATTTAATAAAGGTCAAATTAAG
+ATAACTGCTGATGGAAATAATTACACGATTGATTTAAGTAAAAAGTTAAAATTAACTGAC
+ACAAACCGTTATGTTAAAAATCCTAAAAATGCACAAATTGAAGTCATACTCGAAAAATCT
+AACTAA
diff --git a/t/data/group_9.fa b/t/data/group_9.fa
new file mode 100644
index 0000000..f1e867b
--- /dev/null
+++ b/t/data/group_9.fa
@@ -0,0 +1,15 @@
+>abc_00010
+ATGACACATTTGACAAAGGTTTTAGATACACTAACTGGAATATGCGTAGTATTATTATTT
+AGTAAATATTTTGTGGCGTATGCAAATATGGTGTTTGATTGGAATTTAAGATGGTATTTG
+CTAGAAAACATACCACATTTGCCAATTATATTATTTATTCTGATGTTTATTTTCGGAGTA
+CCTTCTGAAATGATAAAAGATAGGCAAAGGAAAAATAACGGTGTTTAA
+>abc_00010
+ATGACACATTTGACAAAGGTTTTAGATACACTAACTGGAATATGCGTAGTATTATTATTT
+AGTAAATATTTTGTGGCGTATGCAAATATGGTGTTTGATTGGAATTTAAGATGGTATTTG
+CTAGAAAACATACCACATTTGCCAATTATATTATTTATTCTGATGTTTATTTTCGGAGTA
+CCTTCTGAAATGATAAAAGATAGGCAAAGGAAAAATAACGGTGTTTAA
+>abc_00010
+ATGACACATTTGACAAAGGTTTTAGATACACTAACTGGAATATGCGTAGTATTATTATTT
+AGTAAATATTTTGTGGCGTATGCAAATATGGTGTTTGATTGGAATTTAAGATGGTATTTG
+CTAGAAAACATACCACATTTGCCAATTATATTATTTATTCTGATGTTTATTTTCGGAGTA
+CCTTCTGAAATGATAAAAGATAGGCAAAGGAAAAATAACGGTGTTTAA
diff --git a/t/data/input_accessory_binary.fa b/t/data/input_accessory_binary.fa
new file mode 100644
index 0000000..ae3b208
--- /dev/null
+++ b/t/data/input_accessory_binary.fa
@@ -0,0 +1,20 @@
+>seq1
+AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
+>seq2
+AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAC
+>seq3
+AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACC
+>seq4
+AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACCC
+>seq5
+AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACCCC
+>seq6
+AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACCCCC
+>seq7
+AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACCCCCC
+>seq8
+AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACCCCCCC
+>seq9
+AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACCCCCCCC
+>seq10
+AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACCCCCCCCC
diff --git a/t/data/input_block_spreadsheet.csv b/t/data/input_block_spreadsheet.csv
new file mode 100644
index 0000000..1ebd7ca
--- /dev/null
+++ b/t/data/input_block_spreadsheet.csv
@@ -0,0 +1,52 @@
+"Gene","Non-unique Gene name","Annotation","No. isolates","No. sequences","Avg sequences per isolate","Genome Fragment","Order within Fragment","Accessory Fragment","Accessory Order with Fragment","QC","Min group size nuc","Max group size nuc","Avg group size nuc","oneblock","oneblockrev","contigwithgaps","nocontigs","threeblocks","threeblocksinversion"
+"bcsC_1","","cellulose synthase subunit BcsC","9","9","1","11","5692","","","",,,,"oneblock_0031","oneblockrev_0020","contigwithgaps_0121","nocontigs_0331","threeblocks_0131","threeblocksinversion_0031"
+"betC_2","","sulfatase","9","9","1","11","1876","","","",,,,"oneblock_0012","oneblockrev_0039","contigwithgaps_0045","nocontigs_0122","threeblocks_0112","threeblocksinversion_0029"
+"comM_2","","putative ATP-dependent protease","9","9","1","11","6422","","","",,,,"oneblock_0050","oneblockrev_0001","contigwithgaps_0197","nocontigs_0540","threeblocks_0250","threeblocksinversion_0050"
+"dmsA4_1","","anaerobic dimethyl sulfoxide reductase subunit A","9","9","1","11","540","","","",,,,"oneblock_0001","oneblockrev_0050","contigwithgaps_0001","nocontigs_0001","threeblocks_0001","threeblocksinversion_0001"
+"dosC","","diguanylate cylase","9","9","1","11","909","","","",,,,"oneblock_0005","oneblockrev_0046","contigwithgaps_0017","nocontigs_0045","threeblocks_0005","threeblocksinversion_0005"
+"dsbA_3","","Thiol:disulfide interchange protein","9","9","1","11","1676","","","",,,,"oneblock_0009","oneblockrev_0042","contigwithgaps_0033","nocontigs_0089","threeblocks_0009","threeblocksinversion_0009"
+"fadH_1","","2 4-dienoyl-CoA reductase","9","9","1","11","5287","","","",,,,"oneblock_0029","oneblockrev_0022","contigwithgaps_0113","nocontigs_0309","threeblocks_0129","threeblocksinversion_0012"
+"fimD_3","","outer membrane usher protein FimD","9","9","1","11","1813","","","",,,,"oneblock_0011","oneblockrev_0040","contigwithgaps_0041","nocontigs_0111","threeblocks_0111","threeblocksinversion_0030"
+"fliB_2","","lysine-N-methylase","9","9","1","11","1159","","","",,,,"oneblock_0007","oneblockrev_0044","contigwithgaps_0025","nocontigs_0067","threeblocks_0007","threeblocksinversion_0007"
+"fliF","","flagellar MS-ring protein","9","9","1","11","1176","","","",,,,"oneblock_0008","oneblockrev_0043","contigwithgaps_0029","nocontigs_0078","threeblocks_0008","threeblocksinversion_0008"
+"ftsN","","cell division protein FtsN","9","9","1","11","6144","","","",,,,"oneblock_0047","oneblockrev_0004","contigwithgaps_0185","nocontigs_0507","threeblocks_0247","threeblocksinversion_0047"
+"gatY_1","","fructose-bisphosphate aldolase","9","9","1","11","5872","","","",,,,"oneblock_0039","oneblockrev_0012","contigwithgaps_0153","nocontigs_0419","threeblocks_0239","threeblocksinversion_0039"
+"glfT2","","glycosyltransferase cell wall biogenesis","9","9","1","11","4176","","","",,,,"oneblock_0022","oneblockrev_0029","contigwithgaps_0085","nocontigs_0232","threeblocks_0122","threeblocksinversion_0019"
+"group_1000","","membrane protein","9","9","1","11","593","","","",,,,"oneblock_0002","oneblockrev_0049","contigwithgaps_0005","nocontigs_0012","threeblocks_0002","threeblocksinversion_0002"
+"group_1001","","lipoprotein","9","9","1","11","597","","","",,,,"oneblock_0003","oneblockrev_0048","contigwithgaps_0009","nocontigs_0023","threeblocks_0003","threeblocksinversion_0003"
+"group_1004","","arylsulfate sulfotransferase","9","9","1","11","2834","","","",,,,"oneblock_0019","oneblockrev_0032","contigwithgaps_0073","nocontigs_0199","threeblocks_0119","threeblocksinversion_0022"
+"group_1006","","putative inner membrane protein","9","9","1","11","2791","","","",,,,"oneblock_0017","oneblockrev_0034","contigwithgaps_0065","nocontigs_0177","threeblocks_0117","threeblocksinversion_0024"
+"group_1009","","Phage-like protein","9","9","1","11","6416","","","",,,,"oneblock_0049","oneblockrev_0002","contigwithgaps_0193","nocontigs_0529","threeblocks_0249","threeblocksinversion_0049"
+"group_220","","putative glycosyl transferase","9","9","1","11","4174","","","",,,,"oneblock_0021","oneblockrev_0030","contigwithgaps_0081","nocontigs_0221","threeblocks_0121","threeblocksinversion_0020"
+"group_277","","arylsulfate sulfotransferase","9","9","1","11","6149","","","",,,,"oneblock_0048","oneblockrev_0003","contigwithgaps_0189","nocontigs_0518","threeblocks_0248","threeblocksinversion_0048"
+"group_281","","transport system periplasmic binding protein","9","9","1","11","6046","","","",,,,"oneblock_0043","oneblockrev_0008","contigwithgaps_0169","nocontigs_0463","threeblocks_0243","threeblocksinversion_0043"
+"group_283","","periplasmic protein","9","9","1","11","6091","","","",,,,"oneblock_0044","oneblockrev_0007","contigwithgaps_0173","nocontigs_0474","threeblocks_0244","threeblocksinversion_0044"
+"group_284","hemN_2","coproporphyrinogen III oxidase","9","9","1","11","6093","","","",,,,"oneblock_0045","oneblockrev_0006","contigwithgaps_0177","nocontigs_0485","threeblocks_0245","threeblocksinversion_0045"
+"group_288","","permease","9","9","1","11","5969","","","",,,,"oneblock_0041","oneblockrev_0010","contigwithgaps_0161","nocontigs_0441","threeblocks_0241","threeblocksinversion_0041"
+"hemD","","uroporphyrinogen III synthase","9","9","1","11","2788","","","",,,,"oneblock_0016","oneblockrev_0035","contigwithgaps_0061","nocontigs_0166","threeblocks_0116","threeblocksinversion_0025"
+"hsrA_2","","Inner membrane transport protein YieO","9","9","1","11","5993","","","",,,,"oneblock_0042","oneblockrev_0009","contigwithgaps_0165","nocontigs_0452","threeblocks_0242","threeblocksinversion_0042"
+"icsA","","autotransporter MisL","9","9","1","11","5845","","","",,,,"oneblock_0035","oneblockrev_0016","contigwithgaps_0137","nocontigs_0375","threeblocks_0235","threeblocksinversion_0035"
+"kdpD","","sensor protein KdpD","9","9","1","11","4196","","","",,,,"oneblock_0023","oneblockrev_0028","contigwithgaps_0089","nocontigs_0243","threeblocks_0123","threeblocksinversion_0018"
+"ligB_1","","NAD-dependent DNA ligase LigB","9","9","1","11","5819","","","",,,,"oneblock_0034","oneblockrev_0017","contigwithgaps_0133","nocontigs_0364","threeblocks_0234","threeblocksinversion_0034"
+"marT_1","","putative transcriptional regulator MarT","9","9","1","11","5849","","","",,,,"oneblock_0036","oneblockrev_0015","contigwithgaps_0141","nocontigs_0386","threeblocks_0236","threeblocksinversion_0036"
+"nepI","","inner membrane transport protein","9","9","1","11","5866","","","",,,,"oneblock_0038","oneblockrev_0013","contigwithgaps_0149","nocontigs_0408","threeblocks_0238","threeblocksinversion_0038"
+"rffH","","glucose-1-phosphate thymidylyltransferase","9","9","1","11","2778","","","",,,,"oneblock_0015","oneblockrev_0036","contigwithgaps_0057","nocontigs_0155","threeblocks_0115","threeblocksinversion_0026"
+"rpoS","","RNA polymerase sigma factor RpoS","9","9","1","11","4905","","","",,,,"oneblock_0028","oneblockrev_0023","contigwithgaps_0109","nocontigs_0298","threeblocks_0128","threeblocksinversion_0013"
+"SBOV29371","","putative cytoplasmic protein","9","9","1","11","4890","","","",,,,"oneblock_0027","oneblockrev_0024","contigwithgaps_0105","nocontigs_0287","threeblocks_0127","threeblocksinversion_0014"
+"SBOV38871","","integral membrane protein","9","9","1","11","5890","","","",,,,"oneblock_0040","oneblockrev_0011","contigwithgaps_0157","nocontigs_0430","threeblocks_0240","threeblocksinversion_0040"
+"SBOV43201","","putative cytoplasmic protein","9","9","1","11","611","","","",,,,"oneblock_0004","oneblockrev_0047","contigwithgaps_0013","nocontigs_0034","threeblocks_0004","threeblocksinversion_0004"
+"selA_1","","transferase","9","9","1","11","5858","","","",,,,"oneblock_0037","oneblockrev_0014","contigwithgaps_0145","nocontigs_0397","threeblocks_0237","threeblocksinversion_0037"
+"speC_3","","Ornithine decarboxylase inducible","9","9","1","11","4201","","","",,,,"oneblock_0024","oneblockrev_0027","contigwithgaps_0093","nocontigs_0254","threeblocks_0124","threeblocksinversion_0017"
+"sptP","sptx","pathogenicity island 1 effector protein StpP","9","9","1","11","4859","","","",,,,"oneblock_0026","oneblockrev_0025","contigwithgaps_0101","nocontigs_0276","threeblocks_0126","threeblocksinversion_0015"
+"srgB","","putative outer membrane protein","9","9","1","11","1678","","","",,,,"oneblock_0010","oneblockrev_0041","contigwithgaps_0037","nocontigs_0100","threeblocks_0010","threeblocksinversion_0010"
+"stp","","export protein","9","9","1","11","1037","","","",,,,"oneblock_0006","oneblockrev_0045","contigwithgaps_0021","nocontigs_0056","threeblocks_0006","threeblocksinversion_0006"
+"STY3593","","putative regulatory protein","9","9","1","11","2820","","","",,,,"oneblock_0018","oneblockrev_0033","contigwithgaps_0069","nocontigs_0188","threeblocks_0118","threeblocksinversion_0023"
+"STY4162","","putative membrane protein","9","9","1","11","5712","","","",,,,"oneblock_0032","oneblockrev_0019","contigwithgaps_0125","nocontigs_0342","threeblocks_0232","threeblocksinversion_0032"
+"tmcA","","methionine tRNA cytidine acetyltransferase","9","9","1","11","2199","","","",,,,"oneblock_0013","oneblockrev_0038","contigwithgaps_0049","nocontigs_0133","threeblocks_0113","threeblocksinversion_0028"
+"tub","","permease","9","9","1","11","2418","","","",,,,"oneblock_0014","oneblockrev_0037","contigwithgaps_0053","nocontigs_0144","threeblocks_0114","threeblocksinversion_0027"
+"yadA","","membrane protein","9","9","1","11","5768","","","",,,,"oneblock_0033","oneblockrev_0018","contigwithgaps_0129","nocontigs_0353","threeblocks_0233","threeblocksinversion_0033"
+"ybbW_1","","allantoin permease","9","9","1","11","4372","","","",,,,"oneblock_0025","oneblockrev_0026","contigwithgaps_0097","nocontigs_0265","threeblocks_0125","threeblocksinversion_0016"
+"yhaO_2","","membrane protein","9","9","1","11","5310","","","",,,,"oneblock_0030","oneblockrev_0021","contigwithgaps_0117","nocontigs_0320","threeblocks_0130","threeblocksinversion_0011"
+"yicJ_1","","sodium:galactoside symporter","9","9","1","11","6117","","","",,,,"oneblock_0046","oneblockrev_0005","contigwithgaps_0181","nocontigs_0496","threeblocks_0246","threeblocksinversion_0046"
+"yigZ","","protein co-occurring with transport systems","9","9","1","11","2838","","","",,,,"oneblock_0020","oneblockrev_0031","contigwithgaps_0077","nocontigs_0210","threeblocks_0120","threeblocksinversion_0021"
+,
\ No newline at end of file
diff --git a/t/data/kraken_report.txt b/t/data/kraken_report.txt
new file mode 100644
index 0000000..d1c2053
--- /dev/null
+++ b/t/data/kraken_report.txt
@@ -0,0 +1,19 @@
+ 0.39 86 86 U 0 unclassified
+ 99.61 21911 0 - 1 root
+ 99.61 21911 0 - 131567 cellular organisms
+ 99.61 21911 3 D 2 Bacteria
+ 99.60 21908 1 P 1224 Proteobacteria
+ 99.59 21907 9 C 28211 Alphaproteobacteria
+ 99.55 21898 11 O 356 Rhizobiales
+ 99.50 21887 25 F 118882 Brucellaceae
+ 99.39 21862 20467 G 234 Brucella
+ 6.28 1381 1349 S 120577 Brucella ceti
+ 0.10 21 21 - 1423891 Brucella ceti TE10759-12
+ 0.05 11 11 - 1407053 Brucella ceti TE28753-12
+ 0.04 9 0 S 120576 Brucella pinnipedialis
+ 0.04 9 9 - 520461 Brucella pinnipedialis B2/94
+ 0.01 3 0 S 444163 Brucella microti
+ 0.01 3 3 - 568815 Brucella microti CCM 4915
+ 0.00 1 0 S 236 Brucella ovis
+ 0.00 1 1 - 444178 Brucella ovis ATCC 25840
+ 0.00 1 1 S 29461 Brucella suis
\ No newline at end of file
diff --git a/t/data/kraken_test/database.idx b/t/data/kraken_test/database.idx
new file mode 100644
index 0000000..79a2451
Binary files /dev/null and b/t/data/kraken_test/database.idx differ
diff --git a/t/data/kraken_test/database.jdb b/t/data/kraken_test/database.jdb
new file mode 100644
index 0000000..f9ed7b5
Binary files /dev/null and b/t/data/kraken_test/database.jdb differ
diff --git a/t/data/kraken_test/database.kdb b/t/data/kraken_test/database.kdb
new file mode 100644
index 0000000..14a89d0
Binary files /dev/null and b/t/data/kraken_test/database.kdb differ
diff --git a/t/data/kraken_test/taxonomy/names.dmp b/t/data/kraken_test/taxonomy/names.dmp
new file mode 100644
index 0000000..120d91a
--- /dev/null
+++ b/t/data/kraken_test/taxonomy/names.dmp
@@ -0,0 +1,77 @@
+1 | all | | synonym |
+1 | root | | scientific name |
+2 | Bacteria | Bacteria <prokaryote> | scientific name |
+2 | Monera | Monera <Bacteria> | in-part |
+2 | Procaryotae | Procaryotae <Bacteria> | in-part |
+2 | Prokaryota | Prokaryota <Bacteria> | in-part |
+2 | Prokaryotae | Prokaryotae <Bacteria> | in-part |
+2 | bacteria | bacteria <blast2> | blast name |
+2 | eubacteria | | genbank common name |
+2 | not Bacteria Haeckel 1894 | | synonym |
+2 | prokaryote | prokaryote <Bacteria> | in-part |
+2 | prokaryotes | prokaryotes <Bacteria> | in-part |
+1239 | Bacillus/Clostridium group | | synonym |
+1239 | Clostridium group firmicutes | | synonym |
+1239 | Firmacutes | | synonym |
+1239 | Firmicutes | | scientific name |
+1239 | Firmicutes corrig. Gibbons and Murray 1978 | | authority |
+1239 | Gram positive bacteria | | misspelling |
+1239 | Gram-positive bacteria | | genbank common name |
+1239 | Low G+C firmicutes | | synonym |
+1239 | clostridial firmicutes | | synonym |
+1239 | firmicutes | firmicutes <blast1239> | blast name |
+1239 | low G+C Gram-positive bacteria | | common name |
+1239 | low GC Gram+ | low GC gram-positives<blast31968> | common name |
+1279 | "Aurococcus" Winslow and Rogers 1906 | | authority |
+1279 | Aurococcus | | synonym |
+1279 | Staphylococcus | | scientific name |
+1279 | Staphylococcus Rosenbach 1884 | | authority |
+1280 | "Micrococcus aureus" (Rosenbach 1884) Zopf 1885 | | authority |
+1280 | "Micrococcus pyogenes" Lehmann and Neumann 1896 | | authority |
+1280 | "Staphlococcus pyogenes citreus" Passet 1885 | | authority |
+1280 | "Staphylococcus pyogenes aureus" Rosenbach 1884 | | authority |
+1280 | ATCC 12600 | | type material |
+1280 | ATCC 12600-U | | type material |
+1280 | CCM 885 | | type material |
+1280 | CCUG 1800 | | type material |
+1280 | CIP 65.8 | | type material |
+1280 | DSM 20231 | | type material |
+1280 | HAMBI 66 | | type material |
+1280 | JCM 20624 | | type material |
+1280 | Micrococcus aureus | | synonym |
+1280 | Micrococcus pyogenes | | synonym |
+1280 | NBRC 100910 | | type material |
+1280 | NCAIM B.01065 | | type material |
+1280 | NCCB 72047 | | type material |
+1280 | NCTC 8532 | | type material |
+1280 | Staphilococcus aureus | | misspelling |
+1280 | Staphlococcus pyogenes citreus | | synonym |
+1280 | Staphylococcus aureus | | scientific name |
+1280 | Staphylococcus aureus Rosenbach 1884 | | authority |
+1280 | Staphylococcus pyogenes aureus | | synonym |
+1280 | Staphylococus aureus | | misspelling |
+1280 | Streptococcus aureus | | misnomer |
+1385 | Bacillales | | scientific name |
+1385 | Bacillales Prevot 1953 | | authority |
+1385 | Bacillus/Staphylococcus group | | synonym |
+46170 | Staphylococcus aureus aureus | | equivalent name |
+46170 | Staphylococcus aureus subsp. aureus | | scientific name |
+46170 | Staphylococcus aureus subsp. aureus Rosenbach 1884 | | authority |
+90964 | Staphylococcaceae | | scientific name |
+90964 | Staphylococcaceae Schleifer and Bell 2010 | | authority |
+90964 | Staphylococceae | | includes |
+90964 | Staphylococceae Prevot 1940 | | includes |
+90964 | Staphylococcus group | | synonym |
+91061 | Bacilli | | scientific name |
+91061 | Bacilli Ludwig et al. 2010 | | authority |
+91061 | Bacillus/Lactobacillus/Streptococcus group | | synonym |
+91061 | Firmibacteria | | synonym |
+91061 | Firmibacteria Murray 1988 | | authority |
+131567 | biota | | synonym |
+131567 | cellular organisms | | scientific name |
+663951 | Staphylococcus aureus subsp. aureus 0528 | | misspelling |
+663951 | Staphylococcus aureus subsp. aureus 0582 | | synonym |
+663951 | Staphylococcus aureus subsp. aureus TW20 | | scientific name |
+663951 | Staphylococcus aureus subsp. aureus str. TW20 | | equivalent name |
+663951 | Staphylococcus aureus subsp. aureus strain TW20 | | equivalent name |
+2000000000 | Staphylococcus aureus | | scientific name |
diff --git a/t/data/kraken_test/taxonomy/nodes.dmp b/t/data/kraken_test/taxonomy/nodes.dmp
new file mode 100644
index 0000000..77545e1
--- /dev/null
+++ b/t/data/kraken_test/taxonomy/nodes.dmp
@@ -0,0 +1,12 @@
+1 | 1 | no rank | | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |
+2 | 131567 | superkingdom | | 0 | 0 | 11 | 0 | 0 | 0 | 0 | 0 | |
+1239 | 2 | phylum | | 0 | 1 | 11 | 1 | 0 | 1 | 0 | 0 | |
+1279 | 90964 | genus | | 0 | 1 | 11 | 1 | 0 | 1 | 0 | 0 | |
+1280 | 1279 | species | SA | 0 | 1 | 11 | 1 | 0 | 1 | 1 | 0 | |
+1385 | 91061 | order | | 0 | 1 | 11 | 1 | 0 | 1 | 0 | 0 | |
+46170 | 1280 | subspecies | SA | 0 | 1 | 11 | 1 | 0 | 1 | 1 | 0 | |
+90964 | 1385 | family | | 0 | 1 | 11 | 1 | 0 | 1 | 1 | 0 | |
+91061 | 1239 | class | | 0 | 1 | 11 | 1 | 0 | 1 | 0 | 0 | |
+131567 | 1 | no rank | | 8 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | |
+663951 | 46170 | no rank | | 0 | 1 | 11 | 1 | 0 | 1 | 1 | 0 | |
+2000000000 | 663951 | no rank | HI | 9 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | |
diff --git a/t/data/large_accessory_binary_genes.fa b/t/data/large_accessory_binary_genes.fa
new file mode 100644
index 0000000..b5bf343
--- /dev/null
+++ b/t/data/large_accessory_binary_genes.fa
@@ -0,0 +1,94 @@
+>4976_2#9
+CCCCCCCCCCCCCCCACCCCCCAACCCCCCCCCCCCACCCACCCCCCCCCCCCCCCCCCCCCCAACAAAACACACCAACAACCACACAACAAACCAACAACACCCAAACAACACAACACACCAAAAACCCAAACCCAACACAACCAAACCACAACACACCCAACACCCACCAAACCCCCAACCACCCCCCACCCCCACACAACACCCACCAAACCCAACCCACCCCCACCCACCCAACCCCCCCAACACCCACAACACCCACCACCAACCCCACCCCCCCCCACCACCCCACACCCCCCCACCCCCCCCACCCCCCCCCCCCCACCCCCCCAAACCACCACAACACAACCACCACCCCAACACCACACCCCCCCCCCAAACCCCCCCCCCACCCCCACCCCCCCCCCCCCCCCCCACACCCCCCCCCCCACCCCACCCACCCACACCCACCCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCCACCCC [...]
+>4976_3#1
+CCAACACACCACCCCCCCCCCCCACCCCCCCCCCCCAACCCACCCCCACCCCCCCCCCCCCCCAACAAAACCCCCACCCCACACCAACCACAAACAAAACCACCCAAACAAAAACACACACAACCAACACCAACCCCCCAACCCCAAACCACAACCAACACCACCCCAACCACACCCCCCCCCACCCCCCACCCCCACACAACACCCACCACCACCAACCCACCCCCACCCACCCCACCCACCCAACACCCACACAACCCACCCACCCACCACCACCCCCCCCCCACCCCACACCCCCCCCCCCCCCCAACCCCCCCCCCCCCCCCCCCCCCCACCCACACACAACAACCCCCCCCCCAACACCACACCCCCCCCCCCAACCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCACACCCCCCCCCCCCCCCCAACCACCCACAACCACCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC [...]
+>4976_3#10
+CCCACACACAACCCCCCAACCCCCACCCCCCCCCCCACCCCACCCCCACCCCCCCCACCCCCCAACAAAACCCCCACCCCACCACAACCACAACCAACACCACCCAAACAACACCACAAACACCCAACACCAACCCCACACACCAAAACCACAAACAACCACACCCCCACCACACCCCCCCCCACCCCCCACCCCCACACAACACCCACCACCACCAACCCACCCCCACCCACCCCCCCCACCCAACACCCACACAACCCACCCCCACACCCACACCCCCCCCCCACCCCACACCCCCCCCCCCCCCCAACCCCCCCCCCCCCCCCCCCCCCCACCACCACACAACAACCCCCCCCCCAACACCACACCCACCCCCCCAACCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCACCACCCCCCCCCCCCCCCACCCACCCACACCCCCCCCCCCACCCCCCCCCACCCCCCCCCCCCCCCCCCCCCCCCC [...]
+>4976_3#2
+ACACAACACACCCCCCCCCACCCACCCCCCCCCCCCACCCCACCCCCACCCCCCCCCCCCCCCAACAAAACCCCCACCCCACACCACACACAACCAACACCACCCAAACAAAACCACAAACAACCACAACCAACCCCCCACACCCAAAACACAACCAACACCACCCCAACCACACCCCCCCCCACCCCCCACCCCCACACAACACCCACCACCACCAACCCACCCCCACCCACCCCACCCACCCAACACCCACACAACCCACCCACCCACCACCACCCCCCCCCCACCCCACACCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCCCCCACCCACACACAACAACACCCCCCCCAACACCACACCCCCCCCCCCAACCCCCCCCCCCCCCACACCCCCCCCCCCCCCCCCCACACCCCCCCCCCCCCCCCACCCACCCACACCCACCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC [...]
+>4976_3#3
+CCCCCCCCCCCCCCCACAACCCAACAAAAACACCCCACCCACCCCCACCCCCCCCCCCCCCCCAACAACACCCCCCCCCAACCACACACCAAACCAACACAACCCAAACAACACAAAACACCAAAAACCCAAACCCAACACCACCAAACCACAACACACCCAACACCCACCAAACCCCCAACCACCCCCCACCCCCACACAACACCCACCAAACCCAACCCACCCCCACCCACCCCACCCCCCCACCCCCCCCCCCACCCACCACCAACCCCACCCCCCCCCCCCACCCCACACCCCCCCACCCCCCCCACCCCCCCCCCCCCACCCCCCCAAACCACCACAACACAACCACCACCCCAACACAACACCCCCCCCCCAAACCCCCCCCCCCCCCCAACCCCCCCCCCCCCCCCCCACACCCCCCCCCCCACCCCACCCACCCACCACCACCCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCCACCCC [...]
+>4976_6#8
+CCCACACACCCCCACCCAACCCCCACCCCCCCCCCCACCCCACCCCCACCCCCCCCCCCCCCCAACAAAACCCCCACCCCACCACAACCACAACCAACACCAACCAAACAACACCACAAACACCCAACACCAACCCCACACACCCAAACCACAACCAACCACACCCCCACCACACCCCCCCCCACCCCCCACCCCCACACAACACCCACCACCACCAACCCACCCCCACCCACCCCCCCCACCCAACACCCACACAACCCACCCCCACACCCACACCCCCCCCCCACCCCACACCCCCCCCCCCCCCCAACCCCCCCCCCCCCCCCCCCCCCCACCACCACACAACAACCCCCCCCCCAACACCACACCCCCCCCCCCAACCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCACCACCCCCCCCCCCCCCCACCCACCCACACCCCCCCCCCCACCCCCCCCCACCCCCCCCCCCCCCCCCCCCCCCCC [...]
+>4976_7#3
+CCCACAAACCCCACCCCCACCCCACCACACCCACAAAACCCACCCCCACCCCCCCCCCCCCCCAACAAAAACCCCACCCCACCACAACCACAACCAACACCACCCAAACAACAACACAAACCACCAACACCAACCCCACACACCCAAACCACAACCAACCCAACCCCCACCACACCCCCCCCCCACCCCCACCCCCACACAACACCCACCACCACCAACCCACCCCCACCCACCCCACCCCCCCAACACCCACACAACCCCCACCCCCACCCACACCCCCCCCCCACCCCACACCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCCCCCACCACAACAACAAAACACCCCCCCCAACACCACACCCCCCCCCCCAACCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCACACCCCCCCCCCCCCCCCACCCACCCAAACCCACCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC [...]
+>4976_7#4
+CCAACACACCCACCCCCCCCCACACCCCCCCCCCCCAAAACACCCCCACCCCCCCCCCCCCCCAACAAAACCCCCACCCCACCACAACCCAAACCAACACCACCCAAACAACACCACAAACCACCAACACAAACCCCAAACACCCAAACCACAAAACACCACACCCCAACCACACCCCCCCCCACCCCCCACCCCCACACAACACCCACCACACCCAACCCACCCCCACCCACCCCACCCCCCCAACACCCACACAACCCACCCCCACACCACCACCCCCCCCCCACCCCACACCCCCCCCCCCCCCCAACCCCCCCCCCCCCCCCCCCCCCCACCACCACACAACAACCCCCCCCCCAACACCACACCCCCCCCCCCAACCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCACCACCCCCCCCCCCCCCCAACCCCCCACAACCACCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC [...]
+>4976_7#5
+ACCACAACACACCCCCCCACCCCCACCCCCCCACACAACCCACCCCCACCCCCCCCCCCCCCCAACAAAACCCCCACCCCACCACAACCACAACCAAAACCACCCAAACAACAACACACACCACCAACACCAACCCCACACACCCAAACCACAACAACAACCACCCCCACCACACCCCCCCCCACCCCCCACCCCCACACAACACCCACCACACCCAACCCACCCCCACCCACCCCACCCCCCCAACACCCACACAACCCACACCCCCACCACCACCCCCCCCCCACCCCACACCCCCCCCCCCCCCCAACCCCCCCCCCCCCCCCCCCCCCCACCCACACACAACAACACCCCCCCCAACACCACACCCCCCCCCCCAACCCCCCCCCCCCCCAACCCCCCCCCCCACCCCCCCACCACCCCCCCCCCCCCCCACCCACCCACAACCACCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC [...]
+>4976_7#6
+CCCCCCCCCCCCCCCCCAACCCAACCCCCCCCCCCCACCCACACCCCACCCCCCCCACCCCCCAACAACACACACCACAAACCACACACCAAACCAACAAAACCCAAACAACACAACACACCAAAAACCCAAACCCAACACAAACAAACCACAACACACCCAACACCCACCAAACCCCCAACCACCCCCCACCCCCACACAACACCCACCAAACCCAACCCACCCCCACCCACCCCACCCCCCCAACACCCACAACACCCACCACCAACCCACCCCCCCCCCCCCACCCCACACCACCCCACCCCCCCCACCCCCCCCCCCCCACCCCCCCCCACCACCACAACACAACCACCACCCCAACACCACACCCCCCCCCCAAACCCCCCCCCCACCCCAACCCCCCCCCCCCCCCCCCACACCCCCCCCCCCACCCCACCCACCCACCACCACCCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCCACCCC [...]
+>4976_7#7
+CCCCCCCACACCCCCCCCCCCCCACCCCCAACCCCCACCCACCAAACAAAACACCCCCCCCCCAACAACACCCCCACCCCCCCACACACACAACCAACCCCACACAACAAACACAACACACCACCAACCCAAACCAACCACACACAAACCACAACACACCACACACCCACCAAACCCCCACCCACCCCCCACCCCCACACAACACCCACCACCACCAACCCCACCCCACCCACCCAACCACCCCAACACCCACACAACCCACCCACCCCCCACCCCCCCCCCACCACCCCACACCCCCCCCCCCCCCCCACCCCCCCCCCCCCACCCCCCCCCACCCACACAACACACCCCCCCACCCAACACCACACCCCCCCCCCCAACCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCACACCCCCCCCCCCCCCCCACCAACACACCACCACCCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCCACCCC [...]
+>4976_7#8
+CCCCCCCACACCCCCCCCCCCCCACCAAACCCCCCCACCCACCCCACCAACCCACCCCCCCCCAACAAAACCCCCCCCCCCCACCACAAACAAACAACACCACCAAACAAACACAACACACCACCAACCCAAACCCAACACACACAAACCACAACACACCACACACCAACCAAACCCCCACCCAACCCCCACCCCCACACAACACCCACCACCACCAACCCCACCCCACCCACCCAACCCCCCCAACACCCACACAACCCACACCCCCCCCACACCCCCCCCCCCACCCCACACCCCCCCCCCCCCCCCACCCCCCCCCCCCCACCCCCCCCCACCACCACAACACACCCCCCCACCCAACACCACACCCCCCCCCCCAACCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCACACCCCCCCCCCCCCCCCACCCACCCAACACCACCCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCCACCCC [...]
+>4976_7#9
+CCCCCCCCCCCCCCCCCCCCCCAACCAAACCCCCCCACCCACCACCCAACCCCCACACCCCCCAACAACACCCCCCCCCCACCACACACCAAACCAACAACACCCAAACAACACAACACACCAAAAACCCAAACCCAACACACACAAACCACAACACACCCAACACCCACCAAACCCCCAACCACCCCCCACCCCCACACAACACCCACCACACCCAACCCACCCCCACCCACCCAACCCCCCCAACACCCACAACACCCACCACCACACCCACCCCCCCCCCCCACCCCACACCCCCCCACCCCCCCCACCCCCCCCCCCCCACCCCCCCCCACCACCCAAACACAACCCCCACCCCAACACAACACCCCCCCCCCAAACCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCACACCCCCCCCCCCACCCCACCCACCCACCACCACCCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCCACCCC [...]
+>5103_7#1
+CCCCCCCCCCCCCCCACCCAAAAAACCCCAAAAACCAAAAACCCCCCCCCCCCCCCCACCCCCAACAACACAAACCACACACCACACACCAAACCAACAACACCCAAAAACAACAACACACCAAAAACCCAAACCCAACACAACCAAACCACAACACAAAAAACACCAACAAAACCCCCAACCACCCCCCACCCCCACACAACAACCAACAAACCCAACCCACCCCCACCCACCCCACCCCCCCAACACCCACAACACCCACCAACAAACCCACCCCCCCCCCCCACCCCACACCCACCCACCCCCCCCACCCCCCCCCCCCCACCCCCCCCCACCACCCAAAAACAACCCCCACCACAACAACACCCCCCACCCCCAAACCCCCCCCCCACCCCCCCCCCCCCCCCACCCCCCCACAACCCCCCCCCCACCCCACCCACCCACCACCACCCCCCCACCCCCCCCCACCCCCCCCCCCCCCCCCCCCACCCC [...]
+>5103_7#10
+CCAACACACCCCACCCCCCCCACACCCCCCCCCCCCAAAACACCCCCACCCCCCCCCCCCCCCAACAAAACCCCCACCCCACCACAACCCAAACCAACACCACCCAAACAACACCACAAACCACCAACACAAACCCCAAACACCCAAACCACAACCAACCACACCCCACCCACACCCCCCCCCACCCCCCACCCCCACACAACACCCACACCACCCAACCCACCCCCACCCACCCCACCCCCCCAACACCCACACAACCCACCCCCACACCACCACCCCCCCCCCAACCCACACCCCCCCCCCCCCCCAACCCCCCCCCCCCCCCCCCCCCCCACCACCACACAACAACCCCCCCCCCAACACCACCCCCCACCCCCCAACCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCACCACCCCCCCCCCCCCCCAACCCCCCACAACCACCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCACCCC [...]
+>5103_7#8
+CCCACACCAACCCCACCAACCCCCACCCCCCCCCCCACCCCACCCCCACCCCCCCCCCCCCCCAACAAAACCCCCACCCCACCACAACCACAACCAACCCCAACCAAACAACACCACAAACACCCAACACCAACCCCACACACCCAAACCACAACCAACCACACCCCCACCACACCCCCCCCCACCCCCCACCCCCACACAACACCCACCACCACCAACCCACCCCCACCCACCCCCCCCACCCAACACCCACACAACCCACCCCCACACCCACACCCCCCCCCCACCCCACACCCCCCCCCCCCCCCAACCCCCCCCCCCCCCCCCCCCCCCACCACCACACAACAACCCCCCCCCCAACACCACACCCACCCCCCCAACCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCACCACCCCCCCCCCCCCCCACCCACCCACACCCCCCCCCCCACCCCCCCCCACCCCCCCCCCCCCCCCCCCCCCCCC [...]
+>5103_7#9
+CAAAAACACCACCCCCCCCACCCACCAAACCCCCCCAACCCACCCCCACCCCCCCCCCCCCCCAACAAACACCCCACCCCACACCAACCACAAACAACACCACCCAAACAAAAACACACACAACCAACACCAACCCCCCACACCCAACACACAACCAACACCACCCCCACCACACCCCCCCCCACCCCCCACCCCCACACAACAACCACCACCACCAACCCACCCCCACCCACCCCACCCACCCAACACCCACACAACCCACCCACCCACCACCACCCCCCCCCCACCCCACACCCCCCCCCCCCCCCAACCCCCCCCCCCCCCCCCCCCCCCACCCACACACAACAACACCCCCCCCAACACAACACCCCCCCCCCCAACCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCAACCCCCCCCCCCCCCCCACCCACCCACACCCACCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC [...]
+>5116_2#1
+CCCACACCACCCCCACCAACCCCCACCCCCCCCCCCACCCCACCCCCACCCCCCCCACCCCCCAACAAAACCCCCACCCCACCACAACCACAACCAACACCACCCAAACAACACCACAAACACCCAACACCAACCCCACACACCAAAACCACAACCAACCACACCCCCACCACACCCCCCCCCACCCCCCACCCCCACACAACACCCACCACCACCAACCCACCCCCACCCACCCCCCCCACCCAACACCCACACAACCCACCCCCACACCCACACCCCCCCCCCACCCCACACCCCCCCCCCCCCCCAACCCCCCCCCCCCCCCCCCCCCCCACCACCACACAACAACCCCCCCCCCAACACCACACCCCCCCCCCCAACCCCCCCCCCCCCCCAACCCCCCCCCCCCCCCCCCACCACCCCCCCCCCCCCCCACCCACCCACACCCCCCCCCCCACCCCCCCCCACCCCCCCCCCCCCCCCCCCCCCCCC [...]
+>5116_2#11
+CCAACACACCCAACCCCCCCACCACCCCCCCCCCCCAAAACACCCCCACCCCCCCCCCCCCCCAACAAAACCCCCACCCCACCACAACCCAAACCAACACCACCCAAACAACACCACAAACCACCAACACAAACCCCAAACACCCAAACCACAACCAACCACACCCCAACCACACCCCCCCCCACCCCCCACCCCCACAAAACACCCACCACACCCAACCCACCCCCACCCACCCCACCCCCCCAACACCCACACAACCCACCCCCACACCACCACCCCCCCCCCACCCCACACCCCCCCCCCCCCCCAACCCCCCCCCCCCCCCCCCCCCCCACCACCACACAACAACCCCCCCCCCAACACCACACCCCCCCCCCCAACCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCACCACCCCCCCCCCCCCCCAACCCCCCACAACCACCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCACCCC [...]
+>5116_2#2
+CCCCCCCCCCCCCCCACCCCCCAACCCCCCCCCACCACCCACCCCCCACACCCCCCCCCCCCCAACAAAACAACCCAACCACCACACACCAAACCAACAACACCCAAACAACACAACACACCAAAAACCCAAACCCAACACAACCAAACCACAACACACCCAACACCAACCAAACCCCCAACCACCCCCCACCCCCACACAACACCCACCAAACCCAACCCACCCCCACCCACCCCACCACCCCAACACCCACAACACCCACCACCAACCCCACCCCCCCCCCCCACCCCACACCCCCCCACCCCCCCCACCCCCCCCCCCCCACCCCCCCAAACCACCACAACACAACCACCACCCCAACACCACACCCCCCCCCCAAACCCCCCCCCCACCCCCACCCCCCCCCCCCCCCCCCACACCCCCCCCCCCACCCCACCCACCCACCACCACCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCACCCC [...]
+>5116_2#3
+CCCCCCCCCCCCCCCCCCCACCAACCAAACCCCCCCACCCACACCCCAACCCCCAACCCCCCCAACAACACAACACAACCACCACACAACAAACCAACACCACCCAAACAACACCACACACCAAAAACCCAAACCCAACACAACCAAACCACAACACACCCAACACCCACCAAACCCCCAACCACCCCCCACCCCCACACAACAACCACCAAACCCAACCCACCCCCACCCACCCCACCCCCCCAACACCCCCAACACCCACCACCAACCCCACCCCCCCCCCCCACCCCACACCCCCCCACCCCCCCCACCCCCCCCCCCCCACCCCCCCCCACCACCACAACACAACCCCCCCCCCAACACCACACCCCCCCCCCAAACCCCCCCCCCACCCCCACCCCCCCCCCCCCCCCCCACACCCCCCCCCCCCCCCCACCCACCCAACACCACCCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCCACCCC [...]
+>5116_2#4
+ACCCCCCCCCCCCCCACCCCCCAACACCCCCCCCCCACAAACCCCCCCCCCCCCCCCACCCCCAACAAAACACACCAACAACCACACACCAAACCAACAACACCCAAACAACACAACACACCAAAAACCCAAACCCAACACAACCAAACCACAACACACCCAACACCCACCAAACCCCCAACCACCCCCCACCCCCACACAACACCCACCAAACCCAACCCACCCCCACCCACCCCACCCCCCCAACACCCACAACACCCACCACCAACCACACCCCCCCCCACCACCCCACACCCCCCCACCCCCCCCACCCCCCCCCCCCCACCCCCCCAAACCACCACAACACAACCACCACCCCAACACCACACCCCCCCCCCAAACCCCCCCCCCACCCCCACCCCCCCCCCCCCCCCCCACACCCCCCCCCCCACCCCACCCACCCACACACACCCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCCACCCC [...]
+>5116_3#7
+CCCCCCCACACCCCCCCCCCCCCACCCCCAACCCCCACCCACCAAACAAAACACCCCCCCCCCAACAACACCCCCACCCCCCCACACACACAACCAACCCCACACAACAAACACAACACACCACCAACCCAAACCAACCACACACAAACCACAACACACCACACACCCACCAAACCCCCACCCACCCCCCACCCCCACACAACACCCACCACCACCAACCCCACCCCACCCACCCAACCACCCCAACACCCACACAACCCACCCACCCCCCACCCCCCCCCCCCCACCCCACACCCCCCCCCCCCCCCCACCCCCCCCCCCCCACCCCCCCCCACCCACACAACACACCCCCCCACCCAACACCACACCCCCCCCCCCAACCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCACACCCCCCCCCCCCCCCCACCAACACACCACCACCCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCCACCCC [...]
+>5116_3#8
+CCAACACACACCCCCCCCACCCCCACCCCCCCACCCAACCCACCCCCACCCCCCCCCCCCCCCAACAAAACCCCCACCCCACCACAACCACAACCAACACCACCCAAACAACAACACACACCACCAACACCAACCCCACACACCCAAACCACAACAACAACCACCCCCACCACACCCCCCCCCACCCCCCACCCCCACACAACACCCACCACCACCAACCCACCCCCACCCACCCCACCCCCCCAACACCCACACAACCCCCACCCCCACCCACACCCCCCCCCCACACCACACCCCCCCCCCCCCCCAACCCCCCCCCCCCCCCCCCCCCCCACCCACACACAACAACCCCCCCCCCAACACCACACCCCCCCCCCCAACCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCCAAACCCCCCCCCCCCCCCCACCCACCCACACCCACCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC [...]
+>5116_3#9
+CCAACACACCCACCCCCCCCCCCACCCCCCCCCCCCAACCCACCCCCACCCCCCCCCCCCCCCAACAAAACCCCCACCCCACACCAACCACAAACAACACCACCCAAACAAAAACACACACAACCAACCCAAACCCCCCACACCCAAACCAAAACCAACACCACCCCCACCACACCCCCCCCCACCCCCCACCCCCACACAACACCCACCACCACCAACCCACCCCCACCCACCCCACCCACCCAACACCCACACAACCCACCCACCCACCACCACCCCCCCCCCACCCCACACCCCCCCCCCCCCCCAACCCCCCCCCCCCCCCCCCCCCCCACCCACACACAACAACCCCCCCCCCAACACCACACCCCCCCCCCCAACCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCACACCCCCCCCCCCCCCCCAACCACCCACAACCACCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC [...]
+>5139_5#3
+CCCCCCCCCCCCCCCCCCCACCCCCCCCCAACCCCCCCCCCCCCCCCCCCCCCACCCACCCCCCCCCCCCCCCCCCCCCCAAACCCCCCCCCCCACACCCCCCCCCCCCCCCCCCACCCCCCCCCCACCCCCCCCCACCCCCCCCCCACCCCCCCCCCCCCCACCCCACCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCAACCCCCCCCCCCCCCCCACCACCCCCCCCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCACCCCCACCCCACCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCACCCCACCCCCCCCCCCCCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCCCCCCC [...]
+>5749_7#1
+CCCCCCCCCCCCCCCCCAACCCAACCCCCAACCCCCACAAACCCCCACCCCCCCCCCCCCCCCAACAACACACAACAACAAACACACACCAAACCAACAACACCCCAACAACACAACACACCAACAACCCAAACCCAACACAACCAAACCACAACACACCCAAAAAACAACAAAAACAAAAAAACAAAAAAAACAAACACAACACCCACCACACCCAACCCACCCCCACCCACCCCACCCCCCCAACACCCACAAAACCCACCACCAACCCCACCCCCCCCCCCCACCCCACACCCACCCACCCCCCCCACCCCCCCCCCCCCACCCCCCCCCACCACCACAACACAACCCCCCCCCCAACACCACACCCCCCCCCCAAACCCCCCCCCCACCCCAACCCCCCCCCCCCCCCCCCACACCCCCCCCCCCCCCCCACCCACCCACCACCACCCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCCACCCC [...]
+>5749_7#2
+CCAACACACCAACCCCCCCCACCACCCCCCCCCCCAAAAACACCCCCACCCCCCCCACCCCCCAACAAAACCCCCACCCCACCACAACCCAAACCAACACCACCCAAACAACACCCAAAACCACCAACCACAACCCCAAACACCCAAACCACAACCAACCACACCCCAACCACACCCCCCCCCACCCCCCACCCCCAAAAAACACCCACACCACCCAACCCACCCCCACCCACCCCACCCCCCCAACACCCACACAACCCACCCCCACACCACCACCCCCCCCCCACCCCACACCCCCCCCCCCCCCCAACCCCCCCCCCCCCCCCCCCCCCCACCACCACACAACAACCCCCCCCCCAACACCACACCCCCCCCCCCAACCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCACCACCCCCCCCCCCCCCCAACCCCCCACAACCACCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCACCCC [...]
+>5749_7#3
+CCCCCCCCCCCCCCCCCCCCCCAACCCCCACCCCCCACCCACACCCCCACCCCCACACCCCCCAACAACACACAACACACACCACACACCAAACCAACACCACCCAAACAACACAACACACCAACAAACCAAACCCAACACAACCAAACCACAACACACCCAACACCCAACAAAACCCCAAAACAAAAACACCCCCACACACAACCAACCAAACAAAACAAACAAACAAAAAAAACAACCCACAAAAACCCACAACACCCACCACCAACCCCACCCCCCCCCCCCACCCCACACCCCCCCACCCCCCCCACCCCCCCCCCCCCACCCCCCCCCACCACCACAACACAACCCCCCCCCCAACACCACACCCCCCCCCCAAACCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCACACCCCCCCCCCCACCCCACCCACCCACCACCACCCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCCACCCC [...]
+>5749_7#4
+CCCCCCCCCCCCCCCCCCCCCCAACACCCACACCCCACAAACCACCACCCCCCCCCCCCCCCCAACAACACACCACAAACACCACACACCAAACAAACAAAACCCCAACAACACAACACACCAACAACCCAAACCCAACACAACCAAACCACAACACACCCAAAAAACACCAAACACAAAACCACCCCCCACCCCCACACAACACCCACCACACCCAACCCACCCCCACCCACCCCACCCCCCCAACAAAAAAAACACCCACCACCAACCACACCCCCCCCCCCCACCCCACCCCCCCCCACCCCCCCCACCCCCCCCCCCCCACCCCCCCAAACCACCACAACACAACCCCCACCCCAACACCACACCCCCCCCCCAAACCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCACACCCCCCCCCCCCCCCCACCCACCCACCAACACCCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCCACCCC [...]
+>5749_7#5
+CCCACACCAACCCACCCAACCCCCACCCCCCCCCCCACCCCACCCCCACCCCCCCCCCCCCCCAACAAAACCCCCACCCCACCACAACCACAACCAACACCAACCAAACAACACCACACACACCCAACACCAACACCACACACCCAAACCAAAACCAACCACACCCCCACCACACCCCCCCCCACCCCCCACCCCCACACAACACCCACCACCACCAACCCACCCCCACCCACCCCCCCCACCCAACACCCACACAACCCACCCCCACACCACCACCCCCCCCCCACCCCACACCCCCCCCCCCCCCCAACCCCCCCCCCCCCCCCCCCCCCCACCACCACACAACAACCCCCCCCCCAACACCACACCCCCCCCCCCAACCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCACCACCCCCCCCCCCCCCCACCCACCCACACCCCCCCCCCCACCCCCCCCCACCCCCCCCCCCCCCCCCCCCCCCCC [...]
+>8016_2#61
+CCCCCCCCCCCCCCCCCAACCCAACCCCCCCCCACCACCCACCACCCAACCCCCCCCCCCCCCAACAACACCCCCCCCCAACCACACACCAAACCAACACCACCCAAACAACACCACACACCAACAACCCAAACCCAACACAACCAAACCACAACACACCCAACACCCACCAAACCCCCACCCACCCCACACCCCCACACAACACCAACCAAACCCAACCCACCCCCAAACACACCACCCCCCCAACACCCACAACAAAAAACACAAACCCCACCCCCCCCCCCCACCCCACACCCCCCCACCCCCCCCACCCCCCCCCCCCCACCCCCCCAAACCACCACAACACAACCACCACCCCAACACCACACCCCCCCCCCAAACCCCCCCCCCCCCCCAACCCCCCCCCCCCCCCCCCACACCCCCCCCCCCACCCCACCCACCCACCACCACCCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCCACCCC [...]
+>8016_2#62
+CCCCCCCCCCCCCCCCCCCCCCAACAAAACCCCCCCACAAACCCCCCCACCCCCCAACCCCCCAACAACACACCACACACACCACACAACAAACCAACAAAACCCAAACAACACAACACACCAACAACCCAAACCCAACACAAACAAACCACAACACACCCAACACCCACCAAACCCCCAACCACCCCCCACCCCCACACAACACCCACCAAACCCAACCCACCCCCACCAAACCCACCCCCCCAACACCCAAAACACCCACCACAAACAACACCCCCCCCCCCCACCCCACACCACCCCACCCCCCCCACCCCCCCCCCCCCACCCCCCCCCACCACCACAACACAACCACCACCCCAACACAACACCCCCCCCCCAAACCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCACACCCCCCCCCCCACCCCACCCACCCACCACCACCCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCCACCCC [...]
+>8016_2#65
+CCAACACACCACCCCCCCCCCACACCCCCCCCCCCCAAAACACCCCCACCCCCCCCCCCCCCCAACAAAACCCCCACCCCACCACAACCCAAACCAACACCACCCAAACAACACCACAAACCACCAACACACACCCCAAACACCCAAACCACAACCAACCACACCCCAACCACACCCCCCCCCACCCCCCACCCCCAAACAACACCCACACCACCCAACCCACCCCCACCCACCCCACCCCACCAACACCCACACAAAAAACCCCCACACCACCACAAAAAACAAAACCCACACCCCCCCCCCCCCCCAACCCCCCCCCCCCCCCCCCCCCCCACCACCACAACCAAACCCCCCCCCCAACACCACACCCCCCCCCCCAACCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCACCACCCCCCCCCCCCCCCAACCCCCCACAACCACCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCACCCC [...]
+>8016_2#72
+CAAAAACCACACCCCCCCCACCCACCAAACCCCCCCAACCCACCCCCACCCCCCCCCCCCCCCAACAAACACCCCACCCCACACAAACCACAAACAACACCACCCAAACAAAAACACACACAACCAACACCAACCCCCCACACCCAAACCACAACCAACACCACCCCCACCACACCCCCCCCCACCCCCCACCCCCAAACAACAACCACCACCACCAACCCACCCCCACCCACCCCACCCACCCAACACCCACACAACCCACCCACCCACCACCACCCCCCCCCCACCCCACACCCCCCCCCCCCCCCAACCCCCCCCCCCCCCCCCCCCCCCACCCACACACAACAACACCCCCCCCAACACAACACCCCCCCCCCCAACCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCACCACCCCCCCCCCCCCCCACCCACCCACACCCACCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC [...]
+>8016_2#73
+CCCACACCAACCCCCCCCCCCCCACCCCCCCCCCCCAACCCACCCCCACCCCCCCCCCCCCCCAACAAAACCCCCACCCCACACCAACCACAAACAACACCACCCAAACAAAAACACACACAACCAACACCAACCCCCCACACCCAAACCACAACCAACACCACCCCAACCACACCCCCCCCCACCCCCCACCCCCAAACAACACCCACCACCACCAACCCACCCCCACCCACCCCACCCACCCAACACCCACACAACCCACCCACCCACCACCACCCCCCCCCCACCAAACACCCCCCCCCCCCCCCAACCCCCCCCCCCCCCCCCCCCCCCACCCACACACAACAACCCCCCCCCCAACACCACACCCCCCCCCCCAACCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCACACCCCCCCCCCCCCCCCAACCACCCACAACCACCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC [...]
+>8016_2#74
+ACAACACCAACCCCCCCCCCCCCACCCCCCCCCCCCAACCCACCCCCACCCCCCCCCCCCCCCAACAAAACCCCCACCCCACACCAACCACAAACAACACCACCCAAACAAAAACACACACAACCAACACCAACCCCCCACACCCAAACCACAACCAACACCACCCCCACCACACCCCCCCCCACCCCCCACCCCCAAACAACACCCACCACCACCAACCCACCCCCACCCACCCCACCCACCCAACACCCACACAACCCACCCACCCACCACCACCCCCCCCCCACCAAACACCCCCCCCCCCCCCCAACCCCCCCCCCCCCCCCCCCCCCCACCCACACACAACAACCCCCCCCCCAACACCACACCCCCCCCCCCAACCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCACACCCCCCCCCCCCCCCCAACCACCCACAACCACCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC [...]
+>8016_2#75
+CCCCCCCACACCCCCCCCCCCCCACCAAAAACCCCCACCCACCACACAAAAACACCCCCCCCCAACAACACCCCCACCCCCCCACACACACAACCACACCCACACAACAAACACAACACACCACCAACCCAAACCAACCACACACAAACCACAACACACCACACACCCACCAAACCCCCACCCACCCCCCACCCCCACACAAAACCCACCACCACCAACCCCACCCCACCCACCCAACCACCCCAACACCAACACAACCCACCCACCCCCCACACCCCCCCCCCCACCCCAAAAACAAAACAAAAAAACAAAAAAAACAAAAAAAAAAAAAAAACCACCACAACACACCCCCCCACCCAACACAACACCCCACCCCCCAACCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCACACCCCCCCCCCCCCCCCACCCACACACCACCACCCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCCACCCC [...]
+>8016_2#76
+CCCCCCCACACCCCCCCCCCCCCACCCCCCCCCCCCACCCACCCCACACCCACACCCCCCCCCAACAAAACACACAACACCCACCACACACAACCAACCCCACCAAACAAACACAACACACCACCAACCCAAACCCAACACACACAAACCACAACACACCACACACCAACCAAACCCCCACCCACCCCCCACCCCCACACAACACCCACCACCACCAACCCCACCCCACCCACCCAACCCCCCCAACAAACACACAACCCACCCACCCCCCACCCACCCCCCCCCACCCCACACCCCCACCCCCCCCCCACCACAACCAAAAAAAAAAACACCAAAACCACAACACACACCAACAACAAACACCACACCCCCCCCCCCAACCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCACACCCCCCCCCCCCCCCCACCCACCCACCACCACCCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCCACCCC [...]
+>8016_2#77
+CCCCCCCACACCCCCCCAACCCCACCAAACCCCCCCACAAACCACACAAAACAACCCCCCCCCAACAACACCCCCCCCCCCCCAAACACCAAACCAACCCCACACAACAAACACAACACACCACCAACCCAAACCAAACACACACAAACCACAACACACCACACACCAACCAAACCCCCACCCACCCCCCACCCCCACACAACACCCACCACCACCAACCCCACCCCACCCACCCAACCACCCCAACACCCACAACACCCACCCACCCCAACAACCCCCCCCCCCACCCCACAAACCCAACAAAAACCCAAAAAAAACCAAAAAAAAAAAACCACCAACACAACACACCCCCCCACCCAAAACAAAAAAACCAAAAACAAAAAACCCCCCCCCCCAACCCCCCCCCCCCCCCCCCACACCCCCCCCCCCCCCCCACCCACCCACACCCACCCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCCACCCC [...]
+>8016_2#78
+CCCCCCCACACCCCCCCAACCCCACCCCCCCCCCCCACAAACCAAACAAACCACCCCCCCCCCAACAAAACCCCCCCCCACCCAAACACACAACCACACCCACACAACAAACACAACACACCACCAACCCAAACCAACCACACACAAACCACAACACACCACACACCAACCAAACCCCCACCCACCCCCCACCCCCACACAACACCCACCACCACCAACCCCACCCCACCCACCCAACCACCCCAACACCCACACAACCCAACCACCCCCCACCCACCCCCCCCAACCCCAAACCCCACACCCCCAAACAAAACAACCCAAAAAAAAAAAACCAAAACCACAACACACACCACCACCAAAAACCAAACAACCAACAACAAAAACAAAAAACAAACAAAAAAAAAAAACAAAAAAAACACAAAAAAAAAACAAAAACAAAACAACCACAACCCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCCACCCC [...]
+>8016_2#79
+ACCCCCCACACCCCCCCCCCCCCACCAAACCCCCCCACAAACCACACAAAAAACCCCCCCCCCAACAAAACCCCCCCCCCCCCAAACAAAAAACCACACCCACACAACAAACACAACACACCACCAACCCAAACCAACCACACACAAACCACAACACACCACACACCCACCAAACCCCCACCCACCCCCCACCCCCACACAACACCCACCACCACCAACCCCACCCCACCCACCCAACCCCCCCAACACCCACACAACCCACACCCCCCCCACCCACCCCCCACCACCCCACACCCCACACCCCCAAACACCACAACCCAAAAAAAAAACACCACCAACACAACACACACCACCAAAAAAACACAAACAACCCAACCCAAAAAAAAAAACCCCCCCAAAAAAAAAAACAAAAAAAACACAAAAAAAAAACAAAAACAAAAAAAACAAAACCCCCCCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCCACCCC [...]
+>8016_2#81
+ACAAAACCAACCCCCCCAACCCCAACACACCCCCCCACCCAACCCCCACCCCCCCCCCAAAAAAAAAAAACCCCCCCCCCACCAAAACCACAACCAACACCACCCAAACAAAAACACACACCACCAACACCACACCCCCAAACCCAAACCACAACCAACCCCCCCCCCCCCACACCCCCCCCCACCCCCCACCCCCACACAACACCCCACACAACCAACCCACCAAAACCCACCCCACACCCAACACACCCACACAACCCACCCCCACACCACCACAACAAACACACCCCACCCCCCCCCCCCCCCCCAACCCCCCCCCCCCCCCCCCCCCAAACCACAACAACCAAACACCCCCCCCAACACCACACCCACCCCCCCAACCCCCCCCCCCCCCCAACCCCCCCCCCCCCCCCCCACACCCCCCCCCCCCCCCCACCCACCCAAAACCAAACACAACAAAAAAAAAACAAAAAAAAAAAAAAAAAAACAAAA [...]
+>8016_2#82
+ACCACACAAACCCCCCCAACCCCACACCCCCCCCCCACCCAACCCCCACCCCCCCCCCACCCCAACAAAACACACCACACACCAAACACACAAACAACACCACCCAAACAAAAACACACAACACCAACAACAAAACCCCAAACCCAAACCACAACCAACACCCCACCCCCAACACCACCCCCCACCCCCAAAAAAAACACCCAACACACAACACAAAAAAAAAAAAAACCCACCCCACACCCAAAAAACACACAACACCCACCCCCCCACCAACACAACAAACACACCCCACCCCCCCCCCCCCCCCCAACCCCCCCACCCCCCCCCCCCCAAACCACCACAACCAAACACCACCCCCAACACCACAACCAACCCCACAACCCCCCCCCCCCCACAACCCCCCCCCCCCCCCCCCACACCCCCCCCCCCCCCCCACCCACCCACAACCACAAAAAACAAAACAAAAAACCCCCCCCCCCCCAACCCCCCCAC [...]
+>8016_2#83
+ACCACCACAACCCCCCCCCCCCCACACCCCCCCCCCACAAAACCCCCACCCCCCCCCCAACAAAACAAAACACACCACACACCAAACACACAAACAACACCACCCAAACAAAAACACACAACACCAACAACAAAACCCCAAACCCAAACAACAACCAACCCACCACCCCCCACACCACCCCCCACCCCCAAACAAAACACCCAACACACAACACAAAAAAAACAAAAACCCACCCCACACCCAAAAAACACACACAACCCACCCCCCCACCAACACAACAACCCCACCCCACCCCCCCCCCCCCCCCCAACCCCCCCACCCCCCCCCCCCCAAAAAACCAAAACCAAACACCACCCCCAACACCACACAAAACCCCCCAACCCCCCCCCCCCCACCACCCCCCCCCCCCCCCCCCACACCCCCCCCCCCCCCCCACCCACCCACAACCACAAAAAACACAACAAAAAACCCCACCCCCCCCAACCCCACCCC [...]
+>8016_2#85
+ACAAAACAAACCCCCCACCCCCCAACACACCCCCCCACCCAACCCCCACCCCCCCCCCACCCCAAAAAAACCCCCCCCCCACCAAAAACACAACCAACACCACCCAAACAAAAACACACACCACCACAACCAACCCCAAAAACCCAAACCACCACCAACCCCACCCCCCCCACACCCCCCCCCACCCCCAAAACCAACACAACACACCACACAACCAACCCACCACAACCCACCACAACCCCCAAACACCCCCACAACCCACCCCCACACCACCACCAAAAACACACCCCACCCCCCCCCCCCCCCCCAACCCCCCCCCCCCCCCCCCCCCCCAAAACCACAACCAAACACCCCCCCCAACACCACACCCAACCCCCCAACCCCCCCCCACAACCCACCCCCCCCCCCCCCCCCCACACCCCCCCCCCCCCCCCACCCACCCCACCCCCAACACAACAAAAACCCACCAAAAAAAAAAAAAAAAAAAAAACA [...]
+>8016_2#86
+ACCACACCACCCCCCCACCCCCCACACCCCCCACCCACACCACCCCCACCCCCCCCCCAAACAAACAAAACACACCACACACAAAAACCACAACCAACACCCCACAAACAAAACCACACCCCACCAACACCCCCACCCCAAACCCAAACAACAACCAACACCCCACCCACCACACCCCCCCCCACCCCCAAAACCAACACCACACACCACACACCCCACCAACACCAACCCACCACACACCCAAAACACACACACAACCCACCCCCCCACCACCACCCCCCACACCCACCACCCCCCCCCCCCCCCCCAACCCCCCCACCCCCCCCCCCCCAAACCACCACAACCAAACACCACCCCCAACACCACACCCAACCCCCCAACCCCCCCCCACAACCCACCCCCCCCCCCCCCCCCCACACCCCCCCCCCCCCCCCACCCACCCACAACCACAACACCCCCCCCCCCCACCCCCCCCCCCCCCCCCCCCCCCCC [...]
diff --git a/t/data/locus_tag_gffs/query_1.gff b/t/data/locus_tag_gffs/query_1.gff
new file mode 100644
index 0000000..2c5c8fb
--- /dev/null
+++ b/t/data/locus_tag_gffs/query_1.gff
@@ -0,0 +1,271 @@
+##gff-version 3
+##sequence-region abc|SC|contig000001 1 15000
+abc|SC|contig000001 Prodigal:2.60 CDS 172 1131 . - 0 gene=different;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:Q2G1X0,protein motif:TIGRFAMs:TIGR01002,protein motif:Pfam:PF07968.6;locus_tag=abc_00001;product=Alpha-toxin,beta-channel forming cytolysin,Leukocidin/Hemolysin toxin family protein;protein_id=gnl|SC|abc_00001
+abc|SC|contig000001 Prodigal:2.60 CDS 1804 1950 . + 0 inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00002;product=hypothetical protein;protein_id=gnl|SC|abc_00002
+abc|SC|contig000001 Prodigal:2.60 CDS 1934 2131 . + 0 inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00003;product=hypothetical protein;protein_id=gnl|SC|abc_00003
+abc|SC|contig000001 Prodigal:2.60 CDS 2621 3337 . - 0 inference=ab initio prediction:Prodigal:2.60,protein motif:CLUSTERS:PRK13350,protein motif:Pfam:PF02876.11;locus_tag=abc_00004;product=superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00004
+abc|SC|contig000001 Prodigal:2.60 CDS 3445 4170 . - 0 gene=speH;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P0C0I6,protein motif:CLUSTERS:PRK13349,protein motif:Pfam:PF02876.11;locus_tag=abc_00005;note=SPE H;product=hypothetical protein,superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00005
+abc|SC|contig000001 Prodigal:2.60 CDS 4265 4990 . - 0 inference=ab initio prediction:Prodigal:2.60,protein motif:CLUSTERS:PRK13043,protein motif:Pfam:PF02876.11;locus_tag=abc_00006;product=superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00006
+abc|SC|contig000001 Prodigal:2.60 CDS 5428 6429 . + 0 eC_number=2.1.3.3;gene=argF;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P99073,protein motif:CLUSTERS:PRK04284,protein motif:Cdd:COG0078,protein motif:TIGRFAMs:TIGR00658,protein motif:Pfam:PF00185.1;locus_tag=abc_00007;product=Ornithine carbamoyltransferase,ornithine carbamoyltransferase,Ornithine carbamoyltransferase,ornithine carbamoyltransferase,Aspartate/ornithine carbamoyltransferase%2C Asp/Orn b [...]
+abc|SC|contig000001 Prodigal:2.60 CDS 6449 7384 . + 0 eC_number=2.7.2.2;gene=arcC1;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:Q7A627,protein motif:CLUSTERS:PRK12353,protein motif:TIGRFAMs:TIGR00746,protein motif:Pfam:PF00696.22;locus_tag=abc_00008;product=Carbamate kinase 1,putative amino acid kinase,carbamate kinase,Amino acid kinase family protein;protein_id=gnl|SC|abc_00008
+abc|SC|contig000001 RNAmmer:1.2 rRNA 7556 9112 . + 0 inference=COORDINATES:profile:RNAmmer:1.2;locus_tag=abc_01705;product=16S ribosomal RNA
+abc|SC|contig000001 Prodigal:2.60 CDS 9419 9646 . + 0 inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00010;product=hypothetical protein;protein_id=gnl|SC|abc_00010
+abc|SC|contig000001 Prodigal:2.60 CDS 9952 10899 . - 0 inference=ab initio prediction:Prodigal:2.60,protein motif:Pfam:PF03595.11;locus_tag=abc_00011;product=C4-dicarboxylate transporter/malic acid transport protein;protein_id=gnl|SC|abc_00011
+abc|SC|contig000001 Prodigal:2.60 CDS 11148 11336 . + 0 inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00012;product=hypothetical protein;protein_id=gnl|SC|abc_00012
+abc|SC|contig000001 Aragorn:1.2.34 tRNA 11803 11878 . - 0 inference=COORDINATES:profile:Aragorn:1.2.34;locus_tag=abc_00013;product=tRNA-Arg(tct)
+abc|SC|contig000001 Prodigal:2.60 CDS 12241 12375 . + 0 inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P11699,protein motif:Pfam:PF05480.5;locus_tag=abc_00014;product=Gonococcal growth inhibitor III,Staphylococcus haemolytic protein;protein_id=gnl|SC|abc_00014
+abc|SC|contig000001 Prodigal:2.60 CDS 12432 12566 . + 0 inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P11699,protein motif:Pfam:PF05480.5;locus_tag=abc_00015;product=Gonococcal growth inhibitor III,Staphylococcus haemolytic protein;protein_id=gnl|SC|abc_00015
+abc|SC|contig000001 Prodigal:2.60 CDS 12699 13385 . + 0 eC_number=3.-.-.-;gene=yfnB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:O06480,protein motif:CLUSTERS:PRK09449,protein motif:TIGRFAMs:TIGR02254,protein motif:Pfam:PF00702.1;locus_tag=abc_00016;product=Putative HAD-hydrolase yfnB,dUMP phosphatase,HAD hydrolase,haloacid dehalogenase-like hydrolase;protein_id=gnl|SC|abc_00016
+##FASTA
+>abc|SC|contig000001
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
+ATACCCACCACATTTGGTGGAGAACCAAAAATTAGCCGAAAAACATCATTTCTGAAGTTA
+TCGGCTAAAGTTATAAATTATATTTATTTGTACATGAACAAATAATTTACATTAATTTGT
+CATTTCTTCTTTTTCCCAATCGATTTTATATCTTTCTGAAGAACGATCTGTCCATTTATC
+TTTAGTATTGGTACCTTTCCAATTTGTTGAAGTCCAATGCAATTGGTAGTCATCACGAAC
+TCGTTCGTATATTACATCTATATTTGTTTGTTGTTTGGATGCTTTTCTATCCATAGTAAT
+AACTGTAGCGAAGTCTGGTGAAAACCCTGAAGATAATAGAGAACTTGCTTTGTTAGGATC
+AAGGAAGTTCTCTGCTGCTTTCATAGAACCATTTCTAGTTTTCATGAAAAGTTGATTGCC
+ATATACCGGGTTCCAAGAATCTCTATCATATGGTCCCCAATTTTGATTCACCATATTGTT
+AAATATCACTTTCCAGCCTACTTTTTTATCAGTTGGGCTCTCTAAAATTGTTTTGAAATC
+AGGTTGAACATATTTCAGTGTATGACCAATCGAAACATTTGCACCAATAAGGCCGCCAAT
+TTTTCCTGTATCATCACCAGTAACATTACCGTTGAATCCATAAGTTAAAGTACTCATATA
+CTCTTTTGTATCAATCGAATTTCTTGGATAGTAATCAGATATTTGAGCTACTTCATTATC
+AGGTAGTTGCAACTGTACCTTAAAGGCTGAAGGCCAGGCTAAACCACTTTTGTTAGCACC
+TTCTTCGCTATAAACTCTATATTGACCAGCAATGGTACCTTTCGTTCTAATAACTAGCAG
+TTTTTTATTGTGATTTTTATCATCGATAAAACTATAAAATACTTTTTTGTGCATGCCATT
+TTCTTTATCATAAGTGACTAAATCACCTGTTTTTACTGTAGTATTGCTTCCAATATCTGT
+AGTACCGGTTTTAATATTAATATCAGAATCTGCGGCATTAGCGACAGGATTCATTAATAT
+GGAACCTAGCAATAGTGTTGTTGTTACTGAGCTGACTATACGTGTTTTCATTTTCATCAT
+CCTTCTATTTTTTTTAACGATTTGAGGAAACAATAATCAATATGTCAATTTAGAATATTG
+CAGTTGAGACATATCAAATATTTATAATCGTTTATATTAGTATATTTAATGTAGCAACTG
+ATAAATTACTGAGTGATGATGAGTGATTATTTTAAGAATATGTTTTTAACTTTTATTTAA
+AATTTGAAAGGAAGCATTTCAATTTCGAGGGTTAGTCAAAGTTGAATAAATTCTTTATGA
+AACAAGGAAAAGACATAGCTAATTTTATTGATTAATTTCTTTAAAACTAATGATTTGTTT
+GATTTAAAAATGTAATCGATTACAATATAAAAATACAAATATCTTAGAATTAAATCAATT
+AATTAACTATTAAATAAAAATTAAATATATATTAACTACTGTAAATTAATAAATAGAAAT
+AGAGAAAAAGGGTATTAATTATGTTTGGAATTTCGTCGGGAATAATTTTTGCCATTACAT
+AGAAATATCTAATAGATAATGAAAAAGTATCGTATGTATTTTTAATATAGTGTAAAATAT
+CATATGTAAAATAAAATGTAGATTTTTAGTTAGAGGCATTATAAGAAAATTTTGAGTATA
+GGTTAGCTTTTAATTATGAATCTTATTGAAATTTGATTAATAAATATATGATAGGGGATT
+AAAATGAAACTATTTTATATCGTATTTCTTATTATTATATGGCTGAATATATTTTTAGGA
+AATGAAATTATCCATACACTGACTGTTTTAATAACAACATTGTATATTGTTAATTCAAGA
+AAGGGGATTAAAAATGACAGAGTTGAATAATATTATAAACTCTCTTCAATCTTTGTTTGA
+GTCTGAATCAGGCTATAAAATTTCGAAAAATTCAGGAGTTCCATATCAAACAGTACAAGA
+TTTAAGAAATGGGAAAACCAAACTAGAAGATGCTAGATTTAGAACGATTATTAAACTTTA
+TAGTTACTATGTCTCATTAAAAGAACATTAATCATGGGACAATAAAGTATTGCTATAATA
+ATTGAATCATTAAATGAAGGAATAGAGCCTAAGACATAATAAATCAATGTCTTAGGCTCT
+ACAATATTATATTGGTAGTAGTTGACCGAATGAAAATGACCATGTAACAAGCATTTTTGG
+GGCCCCAACACAGAAGCTGACGAAAAGTCAGCTTACAATAATGTGCAAGTTGGGGATGGG
+CCCCAACACAGAGAATTTCAAAAAGAAATTCTACAGACAATGCAAGTTGGCGGGGCCCCA
+ACATAGAGAAATTCAAAAAGAAATTCTACAGACAATGCAAGTTGGGGAGTGACAACGAAA
+TAAATTTTATAAAATACCATTTCTGTCACATTCCTACTCCCAATTCCATTTAAATATATA
+GAAAATTTCACCTATTATATACATCATACACTTTAAAAATTATCATTTAAATAATCTGAT
+TTGGAATTAAAGTGCATGAAGTATAAGTCACCTTCATATACTAATCAAAGAGGACGTCAA
+CAGTTATTTTATTAGGATTTTTAACATAAACATTTGCTAGATCTGAATGTAATCTTTTGC
+TTAAATCAATAGTGTAGTTATTACCGCCACCGGTGATCTTAAGCTTACCTTTATTACGAT
+TTTCGGTATATAATATTTTATTTTTTATTAACGCTTCTCGTGCACGGAAATCGATTTCTT
+TCAATGTTAATACTGGTTTATTGCCTTGGTATATTTTATGCGCACCAATAATCGTTTGTA
+GTTTATCTTTGTATTGCACAAAAAGATTATAAGTTTTATCAGAAGGTTTTGCGGCTGGTG
+TAACGCCACCTGTAAATGTCTCTCTATAAGACCACCATAACTGATCAGTATCTTTGTCTT
+TTAGTCCAAACACATCTACGTAACGATCTTTTAACTGATTAATATTTCCCCAACTTTCAG
+CGCCCCATAAAGATATATGTGCTGACCATGAATATCTCTTAAGTTCAACATAAATGTTTC
+CATTATCATATTGATATAGCCATTTATTTGAAAATGAAAAATGAGGCTGTGTGTAATATT
+TAATTAATTCATTGATGTTAGTTTCATCTTGACCAATGCTATAAGCTTTAGCTTCAGAGT
+AAAAACTAAATACTGGTTTTTGATTTTGAGGTAATACAGTACCTAATAGTAATAATGTTG
+TCGTTAAAATTATATTTTTCGTGATGTTCTTACTCATTAGAACATCTCCTTTCAGAGGAA
+TCATGATACGAGGAATAAGAAATTTAAATGTGAGCGAAGTCAATATAGTATTTGCGATTA
+TTTTTATTAACTCCATTATTATTGTTAGTTTGATTTTTCGAGGATAACTTCAATTTTTGC
+ATTTTGAGGTTTTTTAACATATCTATTTGCATCAGTTGATGGCAACCTTTTACTTAAATC
+TATTGTGTAGTTATTGTCTGTACCTGTTATTTTAATTTGTCCTTTATTATAAGAATTATT
+ATATAATTTTTTACTTTTAATTAATGTTTGACGAATACGAAAATCTAATTCTTTTAAAGT
+TAAAACAGGCTTATTGCCTTCATAAACTGGAAATCCGCCAGTAAACGTTTCTGCTTTATC
+TTTATATGTTACATTCAGTTTATAGTGTTTATCGTTAGATGTTGCTGCAGGAGTAACACC
+ACCAGTAAACGTTTCTTGAGATAATGCAAAAGAATCAATGGTTTCTTGGTCTTTTATGCC
+AAAAATATCAACGCTTTTATTTCTTAATTGGTTGATATTGCCCCAACTTTCAGGTCCATA
+AACTTGAATATGACTATACCAAGAAAACTGTAACAACGTTGCATGAATCGTACCGTTATC
+TTTTTGCCATAACGTACTGTTAGAGAAGGTTAAATATTTTTGCGAGTAATATTTAGTTAA
+CTCATTAACGTTAGTTTCGTTTTGATTTATATAATAAGCTTTCGCTTCAGATGAAGAATT
+GATAGGTGTATTAGGAAATTGTGTAAATGCTGTACCTAATAGTAACAATGTTGTTGATAA
+AATAATTTTTTTCGTGATGTTATTGTTCATTCGAATTTCTCCTTTGAGTATTGTTGGAAT
+GTTTAATTATAAAAAGGGGTTAATTAGATAATTGAAATTATCCGCATTTACAAAAGGTAA
+TAGGTTAGTTAGATTTTTCGAGTATGACTTCAATTTGTGCATTTTTAGGATTTTTAACAT
+AACGGTTTGTGTCAGTTAATTTTAACTTTTTACTTAAATCAATCGTGTAATTATTTCCAT
+CAGCAGTTATCTTAATTTGACCTTTATTAAATTCTCCGTTATATAACTTTTTATTCTTTA
+TTAATGTTTGACGAATACGGAAATCTAATTCTTTTAAAGTTAATACTGGTTTATTTCCTT
+TGTAAAATTCATGTCCACCGATGATAGTTTGTTGTTTATCACTATATTTTAAAAATAGTC
+TATAAGGTTTATCAGATGAAGTAGCTGCTGGCGTAACACCACCAGTAAATGTTTCATCAT
+AAGTCCAGTAACCTTCAACTGTGTCCTCATCTTTAGTTCCAAATATATCAACGTATTTAT
+TTCTTAACTGATTAATGTTTCCCCAACTCTCGGATCCAAACACTTGAATATGACTATACC
+AAACCCACGTTTGCAATGTTGCATGAATGCTACCATTGGGCTTTTGCCATAGCCATTTTC
+CAGATAATGAAAAATGCGGCTGAGTGTAATATTTGATTAACTCATTGATATTAGTCTCGT
+TTTCACTGATATTATAGGCTTTTGCTTCAGATGAAAAACTGATTGGTGTTTTAGGAAGTT
+GTGTTGATGTGGTTCCTAAAAGTAACAATGCTGTTGATAAAACTAATTTATTCATGATGT
+TCTTTTTCATATGAAAATCTCCTTTGCGTGAATTACCCAAAGTATATAAGCTATTACACC
+GATTCGGAATTAAATAAAAGCTAAAACTATGTTAAATAAACTTAAACAGTTAGTAGTGTT
+ATTTAAGCAAAACTTATCATTTTTAAGTTTTGGACAGAAACAGTACTTAATAAAGTAGGC
+GGGAGTTATATATTAAAAACGACACGTTACAATTATTCTCTAATCAATTGCATTAAATTG
+TTTGATAATTGAATTTTCTAACTACTTGAAAAATAGTTATACTTTAAATGTAGTACTTAT
+TTTAATTATTTCCTACTACTTAAATTTAATATTAATAAAATGTTCATTTAATTATTGATA
+AAATATTACAAATTTTAATAGTAGGTTGTGTTTATTTTGTATGCGCTTACAATTTAGGTG
+TAACTAAAATAAAAGGAGTTGTTATTAATGAAAAATTTACGAAACAGAAGTTTTTTAACT
+TTATTAGACTTTTCACGACAAGAGGTAGAATTCTTATTAACACTCTCCGAGGATTTAAAA
+CGTGCTAAATATATTGGCACTGAAAAGCCTATGTTAAAAAATAAAAATATTGCACTGTTA
+TTTGAAAAAGATTCTACAAGAACGCGATGTGCATTTGAAGTTGCAGCGCATGATCAAGGT
+GCAAATGTAACTTATTTAGGCCCAACTGGATCACAAATGGGTAAAAAAGAAACAACTAAA
+GATACTGCACGTGTGCTTGGTGGAATGTATGATGGCATTGAATACCGTGGTTTTTCACAA
+AGAACAGTAGAAACTTTAGCTGAAAATTCAGGCGTACCAGTGTGGAATGGTTTAACTGAT
+GAAGATCATCCTACTCAAGTTCTTGCTGATTTCTTAACAGCAAAAGAAGTCTTAAAAAAA
+GATTATGCAGATATTAACTTTACATATGTTGGAGATGGTCGTAATAACGTTGCAAATGCA
+TTAATGCAAGGTGCTGCCATTATGGGTATGAACTTCCATTTAGTTTGTCCAAAAGAATTA
+AATCCAACAGATGAATTATTAAATCGCTGTAAAAATATTGCCGCTGAAAATGGTGGCAAC
+ATATTAATCACAGATGATATTGACCAAGGTGTAAAAGGTTCGGATGTAATTTACACTGAT
+GTTTGGGTATCAATGGGTGAACCTGATGAAGTATGGAAAGAACGACTTGAATTATTGAAA
+CCATATCAAGTAAATAAAGAAATGATGGATAAAACTGGTAATCCAAATGTTATTTTTGAG
+CATTGCTTACCATCTTTCCATAATGCTGATACGAAAATTGGTCAACAAATTTTTGAAAAA
+TATGGTATTCGAGAAATGGAAGTTACAGATGAAGTATTCGAAAGTAAAGCTTCAGTTGTA
+TTCCAAGAAGCTGAGAACAGAATGCATACAATCAAAGCAGTCATGGTTGCTACATTGGGT
+GAATTTTAAATGATATAAGGAAGTGAATATGATGGCGAAAATAGTAGTAGCATTAGGTGG
+TAATGCTTTAGGAAAATCACCTCAAGAACAACTCGAGCTTGTTAAAAATACTGCGAAATC
+ATTAGTAGGATTAATAACAAAAGGACATGAGATTGTTATTAGTCATGGTAATGGACCACA
+GGTTGGAAGCATTAATTTGGGACTTAACTATGCTGCAGAACATAACCAAGGTCCGGCATT
+TCCATTTGCTGAATGTGGCGCAATGAGTCAAGCTTACATCGGCTATCAATTACAAGAAAG
+CTTACAAAATGAATTGCATTCTATTGGAATGGATAAACAAGTGGTAACACTAGTGACACA
+AGTTGAAGTTGATGAAAATGATCCGGCATTTAACAATCCTTCAAAACCAATTGGGTTATT
+TTACAACAAAGAAGAAGCTGAACAAATTCAAAAAGAAAAAGGATTTATATTTGTTGAAGA
+TGCTGGAAGAGGATATAGACGCGTTGTTCCTTCACCACAACCCATCTCTATTATTGAATT
+AGAGAGTATTAAAACACTTATTAAAAATGATACACTCGTTATTGCTGCTGGTGGTGGAGG
+TATACCAGTAATTAGAGAGCAACATGATGGTTTTAAAGGTATTGATGCAGTTATAGACAA
+AGATAAAACAAGTGCGTTGTTGGGTGCTAATATTCAATGCGATCAATTGATTATTTTAAC
+AGCAATTGATTATGTATATATTAATTTTAACACTGAAAACCAACAGCCTTTGAAAACAAC
+AAATGTTGATGAATTAAAACGATATATAGACGAAAATCAATTTGCAAAAGGAAGTATGTT
+ACCAAAAATTGAAGCAGCCATATCATTTATTGAAAACAATCCAAAAGGAAGTGTGCTTAT
+AACATCATTAAATGAATTAGATGCTGCCTTAGAGGGTAAAGTAGGTACTGTGATTAAAAA
+GTAATTGAATTGAAACGCTTTTCAATTACTATATGTCAAATGCATGATTTTTATTATTTA
+TGTGCACCCCCTGAAAATAATGCCTCTATTTTGATGCGGGGTGCACTTTCTTAATTTATA
+TTTATAAAATCTTTAAGGTAGAAATGCTAGGTTAAATGTCGAAGGAGATGAAACCGTGGA
+AAATACAATTAATGAAAGTGAAAAGAAAAAACGATTTAAATTAAAAATGCCAGGTGCATT
+TATGATTTTATTCATTTTAACGGTTGTTGCAGTTATAGCAACATGGGTTATTCCTGCTGG
+TGCATATTCTAAACTTTCTTACGAACCTTCATCCCAAGAACTAAAGATAGTTAACCCTCA
+TAACCAAGTGAAAAAGGTTCCGGGTACGCAACAGGAACTAGACAAAATGGGGGTTAAAAT
+TAAGATTGAACAATTTAAATCAGGTGCAATTAATAAGCCAGTATCAATTCCGAATACTTA
+TGAAAGATTAAAGCAACATCCAGCTGGACCAGAACAAATAACAAGTAGCATGGTTGAAGG
+TACGATAGAAGCGGTCGATATCATGGTATTCATTCTTGTACTAGGGGGACTTATTGGCGT
+AGTTCAAGCCAGTGGTTCTTTTGAATCGGGATTGTTAGCTTTAACGAAGAAAACAAAAGG
+GCATGAATTTATGCTAATTGTGTTTGTATCAATACTAATGATTATCGGCGGGACGTTATG
+TGGTATTGAAGAAGAAGCTGTAGCATTCTATCCGATTTTAGTCCCTATATTTATAGCGTT
+AGGATACGATTCTATCGTTTCAGTTGGTGCCATATTCCTTGCCAGCTCTGTCGGTAGTAC
+ATTTTCAACTATTAACCCGTTCTCGGTTGTAATTGCCTCTAATGCCGCTGGTACAACTTT
+TACGGATGGCTTGTATTGGAGAATAGGTGCTTGTATTGTCGGTGCGATTTTTGTTATTAG
+TTATTTATATTGGTACTGTAAAAAAATTAAAAACGATCCTAAAGCGTCATATTCTTATGA
+AGACAAAGATGCTTTTGAACAGCAATGGTCTGTATTAAAAGATGACGATAGTGCCCATTT
+TACTTTGCGTAAGAAGATAATCCTTACATTATTTGTACTACCATTTCCAATTATGGTATG
+GGGAGTTATGACGCAAGGTTGGTGGTTCCCAGTTATGGCTTCAGCATTTTTAATATTTAC
+AATTATAATAATGTTTATTGCTGGGACAGGTAAATCTGGATTGGGAGAAAAAGGAACTGT
+AGATGCATTTGTCAATGGTGCATCAAGTTTAGTAGGTGTATCTTTAATTATTGGTTTAGC
+TCGAGGTATTAATTTAGTGTTGAATGAAGGTATGATTTCAGATACAATCTTACACTTTTC
+ATCATCTTTAGTTCAACATATGAGTGGACCATTATTTATCATCGTATTACTATTTATTTT
+CTTCTGTTTAGGTTTTATCGTGCCATCATCTTCTGGATTAGCGGTATTATCAATGCCTAT
+CTTTGCACCACTAGCTGATACAGTAGGTATACCAAGATTCGTCATCGTTACGACATATCA
+ATTTGGTCAATATGCGATGTTATTCTTAGCGCCGACTGGACTTGTTATGGCCACACTACA
+AATGTTAAACATGCGATATTCACATTGGTTCCGATTTGTATGGCCGGTAGTTGCTTTTGT
+ATTGATTTTCGGTGGCGGAGTACTAATTACGCAAGTACTAATTTATTCATAATTTGAAAT
+GCTATATTATAAAAATACTAATTGGGTTTTATGCATCTCGTAGGTTTGTAGAAATACTAA
+ACTAAGCGAGGTGCATTATTATTTTTGATTAAGAAAATAATGACGGTAATGATAACACTA
+GTAAGTAATTGATACAATGCTCTATTTAATAATGATATTTTTAAAATTTGTTTTTAATGT
+AATGTTAGATCTATGGTATATTATATTTATCGTGGTAAATATGTATTTGCTGTAAACAGT
+TTTTGTAACACATGACACATATGGTTGTGAAAATAGCATATATAAAGGATGGCTATAAAT
+GACACATTTGACAAAGGTTTTAGATACACTAACTGGAATATGCGTAGTATTATTATTTAG
+TAAATATTTTGTGGCGTATGCAAATATGGTGTTTGATTGGAATTTAAGATGGTATTTGCT
+AGAAAACATACCACATTTGCCAATTATATTATTTATTCTGATGTTTATTTTCGGAGTACC
+TTCTGAAATGATAAAAGATAGGCAAAGGAAAAATAACGGTGTTTAATTTATCGATATTTA
+GAGGTGATAAAATTTGTCAACTATTACAAAGACTAAAATAAAAATCTTTATTAATTATTT
+TATTGGTATATTAGCCTTGGCGTTTGCTGCTTATATATTATTTAAATAAAGGTTAGAGTG
+AAACGTGTTTATGAACTAGACGTTCTAGTATAGTTACTACAGCTTTAGTCAGAAGGTATC
+ATTGATAAGATCATATTAAATCAAAGAGGCATTGATATACACTAAAAAGAGGCAAGATTA
+CCTGCCTCTTTTTTAGTTATTAAATATGCGTGTTAATTCTTGGTAATAGTGTTACTGAGA
+CGCATTACGAAGAAATTTATCTTGATTTTCCTTTTTTAAAAAGAAGTGAAGATATCCTAT
+AAAGACTCTAAGTACTATTACAGTGGCTAATAACACTTCGATAAACAAAAGACCTTTCCA
+AATATCTGGAAACATAAGTACAGGCAAACTGTTCTTTAAAGCAGTTGCTGAGATTACTAA
+AGGGAATGTGAAAGCTGAAAATACGGGCGAAAAAGGTTCTTTTAGTAATTTAGGCAATTG
+TATAATGATATAAAAATAAAATATTTGAGCTAATATTAAAAATATAATTACGATAAAAGC
+ATTCGCCTTAGGAAAGGCTATAACATATGCTGCAGCGACTAAAGAAAATGGTGCACAAAT
+TGTCGATGTGTTCGGTTTGATTGACGTCTGCAATGGAAATGCTTTTAATCGCTTGAAAAC
+AATAGGTAAGACAATACAAGTAGCTACAAAGCCATATATTACTGTTAATTGACCTATGAA
+AAAACATCCGCTAACGGGTGCCGTCAATCCTGCGATAGCAATACCAATAAAAAGTACAGT
+CCACGAAGGATAAACATTTTCAAGTGAAAAATCTTTTAAATATTTTATTGAAAAAATAAT
+CATATGCGTCATAATTCCCACAAGGCATAAAATCCAAATAGGCGTTATTAAGCTATTGAT
+AAAAGTTATGTTACTAAAAAATGTATTTAAATAAGTAGTACCTAAAAAGCCAGACATGAA
+AAATGTTGTGAACACTGATGAAACTAGAGGACTGTTTAATTGTTCTTTCACATTATTAAA
+ATATTTGATCATAGTACATAAAAGGTGAATCCAAATCAAGAAAGCAAAGATTCCGCAAAC
+AGCGTTTAAAGTAAGAGATAAGTCTTTTAATAGATTACCCAGGCCTAATAATCCTAAGAC
+TAGTCCTGACGTTACTAGAGGTGCTTTTTGAAGTCTCATGATTTACAACCTTTCTTATGT
+GATTTTCTTCACTAATTATATCATGATAGCTATGGCCAATTAATAAGAAGAGTGTGTACT
+ATTACGTTATTAGAGTATGTATATTGGATTGATAGACACATAATTGACATTTAAATCTCA
+AAATTAATGATATTTGAGGTATGCTTTGCAACCTAAATATTGGAATATGTGGAAAAGTAA
+TTATTTAATTTAAATGATGATTGAAGATTTACAAGGGGGTGTACAAAATGAGAAATCAAA
+TTCAAAAACTATTAGACAGTGATTTGAGCAGTTTACATATATCGAAACAAACAGGAGTTC
+CACAAAGCACAATACACAGAATGAGAAAAAAAGAAAGATCATTAGACAATATGTCATTGA
+AAAACGCTGAACTACTTTATAAATTTGCCAATAGTATATTTAGCAATGAAAATTAAGAAG
+AATAATTAGTGAGTTAAATAATTAAAAAACCACGTCTCGATGGACGTGGTTATTTTTTTA
+AATGTATTTAATTATAGGATTTCGGGCCCCTGAAAAGTCCCTAAAATTTTGAATAGTATC
+AAAATCTATAGGAATAATATAATAATAAAAATCTCTACGCATGCAAATGGTGAGTGTTAA
+AAATCTTGGTGTAGTGTTGGTGTAGTTCAGGTGCAGTATAGATGAAATTTGAGCACAAAA
+TTACTTAATTAAAAATGTATAAACAAGTGTCAGACGCGTGTCAATTGTGTGTCAAAAAAT
+TCTATGACGAATAAGCATGCTTGTTTTAATTACTGTATTTTCGGGGCTTATGCGGGGGAC
+GTTTTGGTGACGCATCATACTATATTACTGAAATTCAAAACAAAAAGAGCCCCGTAATCA
+CGGAACTCTTTTGTTTGGTAATGCGTATAAAAATACCTATAAACGTCCTGGGAGGGATTC
+GAACCCCCGACCGATGGCTTAGAAGGCCATTGCTCTATCCAGCTGAGCTACCAGGACACG
+TTTAACAACACAAGAATTATTATATCTAAATGAACTTAAATTAGCAATACCTTGTAAATA
+AAAAATGTTTATATTTTTCACTATTATAGAGCTATTTATCTAAAAAGGTTCAATAAGACT
+TAAATGCGAATTCAGGCAACTTAATTGTGTTAAATACAGTTTTGAATGCCTAACTGTATT
+TCTTTTCTCTTTAAAATACAGTTAAGTACATTATAAGATGTTGTGCGGATAAACAAACTA
+ATTGCATCAAATTTATTTTAAAATAACAACAACAAAACGTTAAGCGAATAACATTTCGGT
+GATTTAAAAGCTACGCACGTTTTTGTTATCTTCAAATTTAAATTTTAAGGAGTGTTTTCA
+ATGGAAGGTTTATTTAACGCAATTAAAGATACCGTAACTGCAGCAATTAATAATGATGGC
+GCAAAATTAGGCACAAGCATTGTGAGCATCGTTGAAAATGGCGTAGGTTTATTAGGTAAA
+TTATTCGGATTCTAATTTCAATATGTTATGTAAGTAATCAGTATTATTTCAAAGGTGAGG
+GAGAGATTTAAATGACTGGACTAGCAGAAGCAATCGCAAATACTGTGCAAGCTGCACAAC
+AACATGATAGTGTGAAATTAGGCACAAGTATCGTAGACATCGTTGCTAACGGTGTGGGTT
+TACTAGGTAAATTATTTGGATTCTAATATAATAACTAATATTCTTTAAAATAAACTGGGT
+GAGCATACTTTAATGTTATGCACTCAGTTTATTTTATTTGCAGAAATTTGAGCCTCTGTT
+AAGATTTAGATACATAGACAATATAGGAGATGGGGAAATTGGGATATAAAAATATTTTGA
+TAGACTTTGATGATACAATTGTTGATTTTTATGATGCAGAAGAATGGGCGTTTCACTATA
+TGGCGAATGTTTTTAATCATAAAGCAACAAAGGATGATTTTTTAACATTTAAAAAAATCA
+ATCACCAACATTGGGAAGCTTTTCAACAAAATAAATTAACGAAGTCTGAAGTATTATCAG
+AACGATTTGTGAATTACTTCAAACATCATCAAATGGAAGTTGATGGGCATCGTGCAGATG
+TGTTATTTAGAAATGGATTAGCAGAAGCTAAAGTTAAATACTTTGATCAAACATTAGAAA
+CAATTGTCGAATTATCGAAAAGACATGATTTATATATTGTTACTAATGGTGTAACCGAAA
+CGCAAAAGAGAAGGTTAAATCAGACGCCGTTGCATAAATATATTAAAAAGATATTTATAT
+CTGAGGAAACAGGATATCAAAAACCTAATCCGGAATTTTTTAATTATGTTTTTAATGATA
+TTGGTGAGGATGAAAGACAGCACTCGATTATAGTTGGAGATTCTTTAACATCTGACATTC
+TAGGTGGAATCAATGCGGGTATAGCTACTTGCTGGTTTAATTTTAGAGGATTTGATCATA
+ATCCAGGAATTATACCTGATTATGAAATTAATTCATGGAAACAACTAAATGATATTGTAC
+GTTAAGACAAATAATTTGAAAATGATTTATATTAGCTTAAGAAAGTAATTGTAAAAACGA
+CACTACGAAAAGATGCATTTTCATGCTCGTAGTGTCGAATATTATTATCTTATGGTTTCC
+ACAATAAGACATCATGTCCCTCTATATTTTTAGCTTCCACATCTGTAAATCCATGATGTA
+AAAAGAAATCCTTAGAATCATTTCTGCCAATGGCTTTAATTGGCATATTGAAACTCTTTG
+CAAAATCAATCAATTCTGAAGCGTACCCTCTGTTTTGATATTTTGGTAATACTTCTAACT
+TCCATAATAATATATAATCTTCAAAATCTGGGAAGTAGATTTCTTCGACATCACCTTTTT
+TTAGTAATGCCATTCTAGCTCCTAATTGATCTCCGACAAATATGCCATAAAATGGTGAAT
+CTGAACTTGCATCAATCATTTGACCGTTTAACTCATTGACCATGTATAAGTCTTTGTTGC
+CAAACGCTCTAAAGTTTTCGAATAATTCGTCAGTTTTGTAATTAATTTCAAGACGTTTGA
+TTTCACTCATATTTATCTACCCCTTATTTGTTTACTACTATTATTATACATTAAACCACT
+TGTGTTTTTCATTGATTTGAAAATGTAAAACAATGAACATTATAAATTTTCCATGATTAA
+ATTGATTTTCAAGCCGTAAAATTGTCAATCACCGGTATAGACTTTATACTATAGTTTGTA
+ATCGCGTACTTAAGGAGAAAAAACATGGACTGTAAAGTAGTTAGTTTAAATGAAAAAGAT
+CAGTTTATACCAAAAATAAAGAGCAGTGACCCTGTAATAACAGGATTATTTCAATATGAT
+GCAGCTCAACAAACTAGTTTTGAAAAAAGGATGTCTAAAGAAAATAATGGAAGAGAAGCG
+GCATTAGCGAATGTTATTCGTGAATATATGAGTGATTTAAAGCTTTCAAATGAACAAGAA
+TTAAACATACAACATTTAGCTAATGGTTCAAAAGTTGTGATTGGTGGACAACAAGCAGGG
+CTTTTCGGGGGACCATTGTATACATTCCATAAAATATTTTCAATCATTACTTTATCTAAG
+GAATTAACGGATACACATAAGCAACAAGTAGTACCAGTTTTTTGGATTGCAGGAGAAGAT
+CATGATTTCGATGAAGTGAATCATACATTTGTTTATAACGAAAATCATGGGTCGCTGCAT
+AAGGTTAAATATCATACAATGGAGATGCCAGAGACGACAGTCTCTAGATATTATCCTGAT
+AAGGCTGAGTTGAAACAAACTTTAAAAACGATGTTCATTCATATGAAAGAAACTGTTCAT
+ACACAAGGTCTACTGGAGATTTGTGACAGAATTATTGACCAATATGACTCGTGGACTGAT
+ATGTTTAAAGCACTACTGCATGAAACATTTAAAGCATATGGCGTTCTATTTATAGATGCG
+CAGTTTGAGCCGTTAAGAAAAATGGAAGCGCCTATGTTTAAAAAGATTTTGAAAAAACAT
+CAGTTGCTTGATGATGCTTTTAGAGCAACACAACAACGTACTCAAAATCAAGGCTTGAAT
+GCGATGATACAAACAGATACAAATGTTCATTTATTCTTACATGATGAAAATATGCGCCAA
+TTAGTTTCGTATGATGGTAAGCATTTTAAATTAAATAAAACAGATAAGACATATATAAAG
\ No newline at end of file
diff --git a/t/data/locus_tag_gffs/query_1.gff.proteome.faa.expected b/t/data/locus_tag_gffs/query_1.gff.proteome.faa.expected
new file mode 100644
index 0000000..78f8a5d
--- /dev/null
+++ b/t/data/locus_tag_gffs/query_1.gff.proteome.faa.expected
@@ -0,0 +1,75 @@
+>abc_00001
+MKTRIVSSVTTTLLLGSILMNPVANAADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGM
+HKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNE
+VAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFK
+TILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAAENFLDPN
+KASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKW
+TDRSSERYKIDWEKEEMTN*
+>abc_00002
+MKLFYIVFLIIIWLNIFLGNEIIHTLTVLITTLYIVNSRKGIKNDRVE*
+>abc_00003
+MTELNNIINSLQSLFESESGYKISKNSGVPYQTVQDLRNGKTKLEDARFRTIIKLYSYYV
+SLKEH*
+>abc_00004
+MSKNITKNIILTTTLLLLGTVLPQNQKPVFSFYSEAKAYSIGQDETNINELIKYYTQPHF
+SFSNKWLYQYDNGNIYVELKRYSWSAHISLWGAESWGNINQLKDRYVDVFGLKDKDTDQL
+WWSYRETFTGGVTPAAKPSDKTYNLFVQYKDKLQTIIGAHKIYQGNKPVLTLKEIDFRAR
+EALIKNKILYTENRNKGKLKITGGGNNYTIDLSKRLHSDLANVYVKNPNKITVDVLFD*
+>abc_00005
+MNNNITKKIILSTTLLLLGTAFTQFPNTPINSSSEAKAYYINQNETNVNELTKYYSQKYL
+TFSNSTLWQKDNGTIHATLLQFSWYSHIQVYGPESWGNINQLRNKSVDIFGIKDQETIDS
+FALSQETFTGGVTPAATSNDKHYKLNVTYKDKAETFTGGFPVYEGNKPVLTLKELDFRIR
+QTLIKSKKLYNNSYNKGQIKITGTDNNYTIDLSKRLPSTDANRYVKKPQNAKIEVILEKS
+N*
+>abc_00006
+MKKNIMNKLVLSTALLLLGTTSTQLPKTPISFSSEAKAYNISENETNINELIKYYTQPHF
+SLSGKWLWQKPNGSIHATLQTWVWYSHIQVFGSESWGNINQLRNKYVDIFGTKDEDTVEG
+YWTYDETFTGGVTPAATSSDKPYRLFLKYSDKQQTIIGGHEFYKGNKPVLTLKELDFRIR
+QTLIKNKKLYNGEFNKGQIKITADGNNYTIDLSKKLKLTDTNRYVKNPKNAQIEVILEKS
+N*
+>abc_00007
+MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTR
+CAFEVAAHDQGANVTYLGPTGSQMGKKETTKDTARVLGGMYDGIEYRGFSQRTVETLAEN
+SGVPVWNGLTDEDHPTQVLADFLTAKEVLKKDYADINFTYVGDGRNNVANALMQGAAIMG
+MNFHLVCPKELNPTDELLNRCKNIAAENGGNILITDDIDQGVKGSDVIYTDVWVSMGEPD
+EVWKERLELLKPYQVNKEMMDKTGNPNVIFEHCLPSFHNADTKIGQQIFEKYGIREMEVT
+DEVFESKASVVFQEAENRMHTIKAVMVATLGEF*
+>abc_00008
+MMAKIVVALGGNALGKSPQEQLELVKNTAKSLVGLITKGHEIVISHGNGPQVGSINLGLN
+YAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVDENDPA
+FNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVPSPQPISIIELESIKTLIKN
+DTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDYVYINF
+NTENQQPLKTTNVDELKRYIDENQFAKGSMLPKIEAAISFIENNPKGSVLITSLNELDAA
+LEGKVGTVIKK*
+>abc_01705
+VENTINESEKKKRFKLKMPGAFMILFILTVVAVIATWVIPAGAYSKLSYEPSSQELKIVN
+PHNQVKKVPGTQQELDKMGVKIKIEQFKSGAINKPVSIPNTYERLKQHPAGPEQITSSMV
+EGTIEAVDIMVFILVLGGLIGVVQASGSFESGLLALTKKTKGHEFMLIVFVSILMIIGGT
+LCGIEEEAVAFYPILVPIFIALGYDSIVSVGAIFLASSVGSTFSTINPFSVVIASNAAGT
+TFTDGLYWRIGACIVGAIFVISYLYWYCKKIKNDPKASYSYEDKDAFEQQWSVLKDDDSA
+HFTLRKKIILTLFVLPFPIMVWGVMTQGWWFPVMASAFLIFTIIIMFIAGTGKSGLGEKG
+TVDAFVNGASSLVGVSLIIGLARGINLVLNEGMISDTILHFSSSLVQHMSGPLFIIVLLF
+IFFCLGFIVPSSSGLAVLSMPIFAPLADTVGIPRFVIVTTYQFGQYAMLFLAPTGLVMAT
+LQMLNMRYSHWFRFVWPVVAFVLIFGGGVLITQVLIYS*
+>abc_00010
+MTHLTKVLDTLTGICVVLLFSKYFVAYANMVFDWNLRWYLLENIPHLPIILFILMFIFGV
+PSEMIKDRQRKNNGV*
+>abc_00011
+MRLQKAPLVTSGLVLGLLGLGNLLKDLSLTLNAVCGIFAFLIWIHLLCTMIKYFNNVKEQ
+LNSPLVSSVFTTFFMSGFLGTTYLNTFFSNITFINSLITPIWILCLVGIMTHMIIFSIKY
+LKDFSLENVYPSWTVLFIGIAIAGLTAPVSGCFFIGQLTVIYGFVATCIVLPIVFKRLKA
+FPLQTSIKPNTSTICAPFSLVAAAYVIAFPKANAFIVIIFLILAQIFYFYIIIQLPKLLK
+EPFSPVFSAFTFPLVISATALKNSLPVLMFPDIWKGLLFIEVLLATVIVLRVFIGYLHFF
+LKKENQDKFLRNASQ*
+>abc_00012
+MRNQIQKLLDSDLSSLHISKQTGVPQSTIHRMRKKERSLDNMSLKNAELLYKFANSIFSN
+EN*
+>abc_00014
+MEGLFNAIKDTVTAAINNDGAKLGTSIVSIVENGVGLLGKLFGF*
+>abc_00015
+MTGLAEAIANTVQAAQQHDSVKLGTSIVDIVANGVGLLGKLFGF*
+>abc_00016
+LGYKNILIDFDDTIVDFYDAEEWAFHYMANVFNHKATKDDFLTFKKINHQHWEAFQQNKL
+TKSEVLSERFVNYFKHHQMEVDGHRADVLFRNGLAEAKVKYFDQTLETIVELSKRHDLYI
+VTNGVTETQKRRLNQTPLHKYIKKIFISEETGYQKPNPEFFNYVFNDIGEDERQHSIIVG
+DSLTSDILGGINAGIATCWFNFRGFDHNPGIIPDYEINSWKQLNDIVR*
diff --git a/t/data/locus_tag_gffs/query_2.gff b/t/data/locus_tag_gffs/query_2.gff
new file mode 100644
index 0000000..8428774
--- /dev/null
+++ b/t/data/locus_tag_gffs/query_2.gff
@@ -0,0 +1,271 @@
+##gff-version 3
+##sequence-region abc|SC|contig000001 1 15000
+abc|SC|contig000001 Prodigal:2.60 CDS 172 1131 . - 0 gene=hly;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:Q2G1X0,protein motif:TIGRFAMs:TIGR01002,protein motif:Pfam:PF07968.6;locus_tag="zzz_00001";product=Alpha-toxin,beta-channel forming cytolysin,Leukocidin/Hemolysin toxin family protein;protein_id=gnl|SC|abc_00001
+abc|SC|contig000001 Prodigal:2.60 CDS 1804 1950 . + 0 inference=ab initio prediction:Prodigal:2.60;locus_tag="zzz_00002";product=hypothetical protein;protein_id=gnl|SC|abc_00002
+abc|SC|contig000001 Prodigal:2.60 CDS 1934 2131 . + 0 inference=ab initio prediction:Prodigal:2.60;locus_tag="zzz_00003";product=hypothetical protein;protein_id=gnl|SC|abc_00003
+abc|SC|contig000001 Prodigal:2.60 CDS 2621 3337 . - 0 inference=ab initio prediction:Prodigal:2.60,protein motif:CLUSTERS:PRK13350,protein motif:Pfam:PF02876.11;locus_tag="zzz_00004";product=superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00004
+abc|SC|contig000001 Prodigal:2.60 CDS 3445 4170 . - 0 gene=speH;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P0C0I6,protein motif:CLUSTERS:PRK13349,protein motif:Pfam:PF02876.11;locus_tag=zzz_00005;note=SPE H;product=hypothetical protein,superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00005
+abc|SC|contig000001 Prodigal:2.60 CDS 4265 4990 . - 0 inference=ab initio prediction:Prodigal:2.60,protein motif:CLUSTERS:PRK13043,protein motif:Pfam:PF02876.11;locus_tag="zzz_00006"";product=superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00006
+abc|SC|contig000001 Prodigal:2.60 CDS 5428 6429 . + 0 eC_number=2.1.3.3;gene=argF;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P99073,protein motif:CLUSTERS:PRK04284,protein motif:Cdd:COG0078,protein motif:TIGRFAMs:TIGR00658,protein motif:Pfam:PF00185.1;locus_tag=zzz_00007;product=Ornithine carbamoyltransferase,ornithine carbamoyltransferase,Ornithine carbamoyltransferase,ornithine carbamoyltransferase,Aspartate/ornithine carbamoyltransferase%2C Asp/Orn b [...]
+abc|SC|contig000001 Prodigal:2.60 CDS 6449 7384 . + 0 eC_number=2.7.2.2;gene=arcC1;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:Q7A627,protein motif:CLUSTERS:PRK12353,protein motif:TIGRFAMs:TIGR00746,protein motif:Pfam:PF00696.22;locus_tag=zzz_00008;product=Carbamate kinase 1,putative amino acid kinase,carbamate kinase,Amino acid kinase family protein;protein_id=gnl|SC|abc_00008
+abc|SC|contig000001 RNAmmer:1.2 rRNA 7556 9112 . + 0 inference=COORDINATES:profile:RNAmmer:1.2;locus_tag="zzz_01705";product=16S ribosomal RNA
+abc|SC|contig000001 Prodigal:2.60 CDS 9419 9646 . + 0 inference=ab initio prediction:Prodigal:2.60;locus_tag="zzz_00010";product=hypothetical protein;protein_id=gnl|SC|abc_00010
+abc|SC|contig000001 Prodigal:2.60 CDS 9952 10899 . - 0 inference=ab initio prediction:Prodigal:2.60,protein motif:Pfam:PF03595.11;locus_tag="zzz_00011";product=C4-dicarboxylate transporter/malic acid transport protein;protein_id=gnl|SC|abc_00011
+abc|SC|contig000001 Prodigal:2.60 CDS 11148 11336 . + 0 inference=ab initio prediction:Prodigal:2.60;locus_tag="zzz_00012";product=hypothetical protein;protein_id=gnl|SC|abc_00012
+abc|SC|contig000001 Aragorn:1.2.34 tRNA 11803 11878 . - 0 inference=COORDINATES:profile:Aragorn:1.2.34;locus_tag="zzz_00013";product=tRNA-Arg(tct)
+abc|SC|contig000001 Prodigal:2.60 CDS 12241 12375 . + 0 inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P11699,protein motif:Pfam:PF05480.5;locus_tag="zzz_00014";product=Gonococcal growth inhibitor III,Staphylococcus haemolytic protein;protein_id=gnl|SC|abc_00014
+abc|SC|contig000001 Prodigal:2.60 CDS 12432 12566 . + 0 inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P11699,protein motif:Pfam:PF05480.5;locus_tag="zzz_00015";product=Gonococcal growth inhibitor III,Staphylococcus haemolytic protein;protein_id=gnl|SC|abc_00015
+abc|SC|contig000001 Prodigal:2.60 CDS 12699 13385 . + 0 eC_number=3.-.-.-;gene=yfnB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:O06480,protein motif:CLUSTERS:PRK09449,protein motif:TIGRFAMs:TIGR02254,protein motif:Pfam:PF00702.1;locus_tag="zzz_00016";product=Putative HAD-hydrolase yfnB,dUMP phosphatase,HAD hydrolase,haloacid dehalogenase-like hydrolase;protein_id=gnl|SC|abc_00016
+##FASTA
+>abc|SC|contig000001
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
+ATACCCACCACATTTGGTGGAGAACCAAAAATTAGCCGAAAAACATCATTTCTGAAGTTA
+TCGGCTAAAGTTATAAATTATATTTATTTGTACATGAACAAATAATTTACATTAATTTGT
+CATTTCTTCTTTTTCCCAATCGATTTTATATCTTTCTGAAGAACGATCTGTCCATTTATC
+TTTAGTATTGGTACCTTTCCAATTTGTTGAAGTCCAATGCAATTGGTAGTCATCACGAAC
+TCGTTCGTATATTACATCTATATTTGTTTGTTGTTTGGATGCTTTTCTATCCATAGTAAT
+AACTGTAGCGAAGTCTGGTGAAAACCCTGAAGATAATAGAGAACTTGCTTTGTTAGGATC
+AAGGAAGTTCTCTGCTGCTTTCATAGAACCATTTCTAGTTTTCATGAAAAGTTGATTGCC
+ATATACCGGGTTCCAAGAATCTCTATCATATGGTCCCCAATTTTGATTCACCATATTGTT
+AAATATCACTTTCCAGCCTACTTTTTTATCAGTTGGGCTCTCTAAAATTGTTTTGAAATC
+AGGTTGAACATATTTCAGTGTATGACCAATCGAAACATTTGCACCAATAAGGCCGCCAAT
+TTTTCCTGTATCATCACCAGTAACATTACCGTTGAATCCATAAGTTAAAGTACTCATATA
+CTCTTTTGTATCAATCGAATTTCTTGGATAGTAATCAGATATTTGAGCTACTTCATTATC
+AGGTAGTTGCAACTGTACCTTAAAGGCTGAAGGCCAGGCTAAACCACTTTTGTTAGCACC
+TTCTTCGCTATAAACTCTATATTGACCAGCAATGGTACCTTTCGTTCTAATAACTAGCAG
+TTTTTTATTGTGATTTTTATCATCGATAAAACTATAAAATACTTTTTTGTGCATGCCATT
+TTCTTTATCATAAGTGACTAAATCACCTGTTTTTACTGTAGTATTGCTTCCAATATCTGT
+AGTACCGGTTTTAATATTAATATCAGAATCTGCGGCATTAGCGACAGGATTCATTAATAT
+GGAACCTAGCAATAGTGTTGTTGTTACTGAGCTGACTATACGTGTTTTCATTTTCATCAT
+CCTTCTATTTTTTTTAACGATTTGAGGAAACAATAATCAATATGTCAATTTAGAATATTG
+CAGTTGAGACATATCAAATATTTATAATCGTTTATATTAGTATATTTAATGTAGCAACTG
+ATAAATTACTGAGTGATGATGAGTGATTATTTTAAGAATATGTTTTTAACTTTTATTTAA
+AATTTGAAAGGAAGCATTTCAATTTCGAGGGTTAGTCAAAGTTGAATAAATTCTTTATGA
+AACAAGGAAAAGACATAGCTAATTTTATTGATTAATTTCTTTAAAACTAATGATTTGTTT
+GATTTAAAAATGTAATCGATTACAATATAAAAATACAAATATCTTAGAATTAAATCAATT
+AATTAACTATTAAATAAAAATTAAATATATATTAACTACTGTAAATTAATAAATAGAAAT
+AGAGAAAAAGGGTATTAATTATGTTTGGAATTTCGTCGGGAATAATTTTTGCCATTACAT
+AGAAATATCTAATAGATAATGAAAAAGTATCGTATGTATTTTTAATATAGTGTAAAATAT
+CATATGTAAAATAAAATGTAGATTTTTAGTTAGAGGCATTATAAGAAAATTTTGAGTATA
+GGTTAGCTTTTAATTATGAATCTTATTGAAATTTGATTAATAAATATATGATAGGGGATT
+AAAATGAAACTATTTTATATCGTATTTCTTATTATTATATGGCTGAATATATTTTTAGGA
+AATGAAATTATCCATACACTGACTGTTTTAATAACAACATTGTATATTGTTAATTCAAGA
+AAGGGGATTAAAAATGACAGAGTTGAATAATATTATAAACTCTCTTCAATCTTTGTTTGA
+GTCTGAATCAGGCTATAAAATTTCGAAAAATTCAGGAGTTCCATATCAAACAGTACAAGA
+TTTAAGAAATGGGAAAACCAAACTAGAAGATGCTAGATTTAGAACGATTATTAAACTTTA
+TAGTTACTATGTCTCATTAAAAGAACATTAATCATGGGACAATAAAGTATTGCTATAATA
+ATTGAATCATTAAATGAAGGAATAGAGCCTAAGACATAATAAATCAATGTCTTAGGCTCT
+ACAATATTATATTGGTAGTAGTTGACCGAATGAAAATGACCATGTAACAAGCATTTTTGG
+GGCCCCAACACAGAAGCTGACGAAAAGTCAGCTTACAATAATGTGCAAGTTGGGGATGGG
+CCCCAACACAGAGAATTTCAAAAAGAAATTCTACAGACAATGCAAGTTGGCGGGGCCCCA
+ACATAGAGAAATTCAAAAAGAAATTCTACAGACAATGCAAGTTGGGGAGTGACAACGAAA
+TAAATTTTATAAAATACCATTTCTGTCACATTCCTACTCCCAATTCCATTTAAATATATA
+GAAAATTTCACCTATTATATACATCATACACTTTAAAAATTATCATTTAAATAATCTGAT
+TTGGAATTAAAGTGCATGAAGTATAAGTCACCTTCATATACTAATCAAAGAGGACGTCAA
+CAGTTATTTTATTAGGATTTTTAACATAAACATTTGCTAGATCTGAATGTAATCTTTTGC
+TTAAATCAATAGTGTAGTTATTACCGCCACCGGTGATCTTAAGCTTACCTTTATTACGAT
+TTTCGGTATATAATATTTTATTTTTTATTAACGCTTCTCGTGCACGGAAATCGATTTCTT
+TCAATGTTAATACTGGTTTATTGCCTTGGTATATTTTATGCGCACCAATAATCGTTTGTA
+GTTTATCTTTGTATTGCACAAAAAGATTATAAGTTTTATCAGAAGGTTTTGCGGCTGGTG
+TAACGCCACCTGTAAATGTCTCTCTATAAGACCACCATAACTGATCAGTATCTTTGTCTT
+TTAGTCCAAACACATCTACGTAACGATCTTTTAACTGATTAATATTTCCCCAACTTTCAG
+CGCCCCATAAAGATATATGTGCTGACCATGAATATCTCTTAAGTTCAACATAAATGTTTC
+CATTATCATATTGATATAGCCATTTATTTGAAAATGAAAAATGAGGCTGTGTGTAATATT
+TAATTAATTCATTGATGTTAGTTTCATCTTGACCAATGCTATAAGCTTTAGCTTCAGAGT
+AAAAACTAAATACTGGTTTTTGATTTTGAGGTAATACAGTACCTAATAGTAATAATGTTG
+TCGTTAAAATTATATTTTTCGTGATGTTCTTACTCATTAGAACATCTCCTTTCAGAGGAA
+TCATGATACGAGGAATAAGAAATTTAAATGTGAGCGAAGTCAATATAGTATTTGCGATTA
+TTTTTATTAACTCCATTATTATTGTTAGTTTGATTTTTCGAGGATAACTTCAATTTTTGC
+ATTTTGAGGTTTTTTAACATATCTATTTGCATCAGTTGATGGCAACCTTTTACTTAAATC
+TATTGTGTAGTTATTGTCTGTACCTGTTATTTTAATTTGTCCTTTATTATAAGAATTATT
+ATATAATTTTTTACTTTTAATTAATGTTTGACGAATACGAAAATCTAATTCTTTTAAAGT
+TAAAACAGGCTTATTGCCTTCATAAACTGGAAATCCGCCAGTAAACGTTTCTGCTTTATC
+TTTATATGTTACATTCAGTTTATAGTGTTTATCGTTAGATGTTGCTGCAGGAGTAACACC
+ACCAGTAAACGTTTCTTGAGATAATGCAAAAGAATCAATGGTTTCTTGGTCTTTTATGCC
+AAAAATATCAACGCTTTTATTTCTTAATTGGTTGATATTGCCCCAACTTTCAGGTCCATA
+AACTTGAATATGACTATACCAAGAAAACTGTAACAACGTTGCATGAATCGTACCGTTATC
+TTTTTGCCATAACGTACTGTTAGAGAAGGTTAAATATTTTTGCGAGTAATATTTAGTTAA
+CTCATTAACGTTAGTTTCGTTTTGATTTATATAATAAGCTTTCGCTTCAGATGAAGAATT
+GATAGGTGTATTAGGAAATTGTGTAAATGCTGTACCTAATAGTAACAATGTTGTTGATAA
+AATAATTTTTTTCGTGATGTTATTGTTCATTCGAATTTCTCCTTTGAGTATTGTTGGAAT
+GTTTAATTATAAAAAGGGGTTAATTAGATAATTGAAATTATCCGCATTTACAAAAGGTAA
+TAGGTTAGTTAGATTTTTCGAGTATGACTTCAATTTGTGCATTTTTAGGATTTTTAACAT
+AACGGTTTGTGTCAGTTAATTTTAACTTTTTACTTAAATCAATCGTGTAATTATTTCCAT
+CAGCAGTTATCTTAATTTGACCTTTATTAAATTCTCCGTTATATAACTTTTTATTCTTTA
+TTAATGTTTGACGAATACGGAAATCTAATTCTTTTAAAGTTAATACTGGTTTATTTCCTT
+TGTAAAATTCATGTCCACCGATGATAGTTTGTTGTTTATCACTATATTTTAAAAATAGTC
+TATAAGGTTTATCAGATGAAGTAGCTGCTGGCGTAACACCACCAGTAAATGTTTCATCAT
+AAGTCCAGTAACCTTCAACTGTGTCCTCATCTTTAGTTCCAAATATATCAACGTATTTAT
+TTCTTAACTGATTAATGTTTCCCCAACTCTCGGATCCAAACACTTGAATATGACTATACC
+AAACCCACGTTTGCAATGTTGCATGAATGCTACCATTGGGCTTTTGCCATAGCCATTTTC
+CAGATAATGAAAAATGCGGCTGAGTGTAATATTTGATTAACTCATTGATATTAGTCTCGT
+TTTCACTGATATTATAGGCTTTTGCTTCAGATGAAAAACTGATTGGTGTTTTAGGAAGTT
+GTGTTGATGTGGTTCCTAAAAGTAACAATGCTGTTGATAAAACTAATTTATTCATGATGT
+TCTTTTTCATATGAAAATCTCCTTTGCGTGAATTACCCAAAGTATATAAGCTATTACACC
+GATTCGGAATTAAATAAAAGCTAAAACTATGTTAAATAAACTTAAACAGTTAGTAGTGTT
+ATTTAAGCAAAACTTATCATTTTTAAGTTTTGGACAGAAACAGTACTTAATAAAGTAGGC
+GGGAGTTATATATTAAAAACGACACGTTACAATTATTCTCTAATCAATTGCATTAAATTG
+TTTGATAATTGAATTTTCTAACTACTTGAAAAATAGTTATACTTTAAATGTAGTACTTAT
+TTTAATTATTTCCTACTACTTAAATTTAATATTAATAAAATGTTCATTTAATTATTGATA
+AAATATTACAAATTTTAATAGTAGGTTGTGTTTATTTTGTATGCGCTTACAATTTAGGTG
+TAACTAAAATAAAAGGAGTTGTTATTAATGAAAAATTTACGAAACAGAAGTTTTTTAACT
+TTATTAGACTTTTCACGACAAGAGGTAGAATTCTTATTAACACTCTCCGAGGATTTAAAA
+CGTGCTAAATATATTGGCACTGAAAAGCCTATGTTAAAAAATAAAAATATTGCACTGTTA
+TTTGAAAAAGATTCTACAAGAACGCGATGTGCATTTGAAGTTGCAGCGCATGATCAAGGT
+GCAAATGTAACTTATTTAGGCCCAACTGGATCACAAATGGGTAAAAAAGAAACAACTAAA
+GATACTGCACGTGTGCTTGGTGGAATGTATGATGGCATTGAATACCGTGGTTTTTCACAA
+AGAACAGTAGAAACTTTAGCTGAAAATTCAGGCGTACCAGTGTGGAATGGTTTAACTGAT
+GAAGATCATCCTACTCAAGTTCTTGCTGATTTCTTAACAGCAAAAGAAGTCTTAAAAAAA
+GATTATGCAGATATTAACTTTACATATGTTGGAGATGGTCGTAATAACGTTGCAAATGCA
+TTAATGCAAGGTGCTGCCATTATGGGTATGAACTTCCATTTAGTTTGTCCAAAAGAATTA
+AATCCAACAGATGAATTATTAAATCGCTGTAAAAATATTGCCGCTGAAAATGGTGGCAAC
+ATATTAATCACAGATGATATTGACCAAGGTGTAAAAGGTTCGGATGTAATTTACACTGAT
+GTTTGGGTATCAATGGGTGAACCTGATGAAGTATGGAAAGAACGACTTGAATTATTGAAA
+CCATATCAAGTAAATAAAGAAATGATGGATAAAACTGGTAATCCAAATGTTATTTTTGAG
+CATTGCTTACCATCTTTCCATAATGCTGATACGAAAATTGGTCAACAAATTTTTGAAAAA
+TATGGTATTCGAGAAATGGAAGTTACAGATGAAGTATTCGAAAGTAAAGCTTCAGTTGTA
+TTCCAAGAAGCTGAGAACAGAATGCATACAATCAAAGCAGTCATGGTTGCTACATTGGGT
+GAATTTTAAATGATATAAGGAAGTGAATATGATGGCGAAAATAGTAGTAGCATTAGGTGG
+TAATGCTTTAGGAAAATCACCTCAAGAACAACTCGAGCTTGTTAAAAATACTGCGAAATC
+ATTAGTAGGATTAATAACAAAAGGACATGAGATTGTTATTAGTCATGGTAATGGACCACA
+GGTTGGAAGCATTAATTTGGGACTTAACTATGCTGCAGAACATAACCAAGGTCCGGCATT
+TCCATTTGCTGAATGTGGCGCAATGAGTCAAGCTTACATCGGCTATCAATTACAAGAAAG
+CTTACAAAATGAATTGCATTCTATTGGAATGGATAAACAAGTGGTAACACTAGTGACACA
+AGTTGAAGTTGATGAAAATGATCCGGCATTTAACAATCCTTCAAAACCAATTGGGTTATT
+TTACAACAAAGAAGAAGCTGAACAAATTCAAAAAGAAAAAGGATTTATATTTGTTGAAGA
+TGCTGGAAGAGGATATAGACGCGTTGTTCCTTCACCACAACCCATCTCTATTATTGAATT
+AGAGAGTATTAAAACACTTATTAAAAATGATACACTCGTTATTGCTGCTGGTGGTGGAGG
+TATACCAGTAATTAGAGAGCAACATGATGGTTTTAAAGGTATTGATGCAGTTATAGACAA
+AGATAAAACAAGTGCGTTGTTGGGTGCTAATATTCAATGCGATCAATTGATTATTTTAAC
+AGCAATTGATTATGTATATATTAATTTTAACACTGAAAACCAACAGCCTTTGAAAACAAC
+AAATGTTGATGAATTAAAACGATATATAGACGAAAATCAATTTGCAAAAGGAAGTATGTT
+ACCAAAAATTGAAGCAGCCATATCATTTATTGAAAACAATCCAAAAGGAAGTGTGCTTAT
+AACATCATTAAATGAATTAGATGCTGCCTTAGAGGGTAAAGTAGGTACTGTGATTAAAAA
+GTAATTGAATTGAAACGCTTTTCAATTACTATATGTCAAATGCATGATTTTTATTATTTA
+TGTGCACCCCCTGAAAATAATGCCTCTATTTTGATGCGGGGTGCACTTTCTTAATTTATA
+TTTATAAAATCTTTAAGGTAGAAATGCTAGGTTAAATGTCGAAGGAGATGAAACCGTGGA
+AAATACAATTAATGAAAGTGAAAAGAAAAAACGATTTAAATTAAAAATGCCAGGTGCATT
+TATGATTTTATTCATTTTAACGGTTGTTGCAGTTATAGCAACATGGGTTATTCCTGCTGG
+TGCATATTCTAAACTTTCTTACGAACCTTCATCCCAAGAACTAAAGATAGTTAACCCTCA
+TAACCAAGTGAAAAAGGTTCCGGGTACGCAACAGGAACTAGACAAAATGGGGGTTAAAAT
+TAAGATTGAACAATTTAAATCAGGTGCAATTAATAAGCCAGTATCAATTCCGAATACTTA
+TGAAAGATTAAAGCAACATCCAGCTGGACCAGAACAAATAACAAGTAGCATGGTTGAAGG
+TACGATAGAAGCGGTCGATATCATGGTATTCATTCTTGTACTAGGGGGACTTATTGGCGT
+AGTTCAAGCCAGTGGTTCTTTTGAATCGGGATTGTTAGCTTTAACGAAGAAAACAAAAGG
+GCATGAATTTATGCTAATTGTGTTTGTATCAATACTAATGATTATCGGCGGGACGTTATG
+TGGTATTGAAGAAGAAGCTGTAGCATTCTATCCGATTTTAGTCCCTATATTTATAGCGTT
+AGGATACGATTCTATCGTTTCAGTTGGTGCCATATTCCTTGCCAGCTCTGTCGGTAGTAC
+ATTTTCAACTATTAACCCGTTCTCGGTTGTAATTGCCTCTAATGCCGCTGGTACAACTTT
+TACGGATGGCTTGTATTGGAGAATAGGTGCTTGTATTGTCGGTGCGATTTTTGTTATTAG
+TTATTTATATTGGTACTGTAAAAAAATTAAAAACGATCCTAAAGCGTCATATTCTTATGA
+AGACAAAGATGCTTTTGAACAGCAATGGTCTGTATTAAAAGATGACGATAGTGCCCATTT
+TACTTTGCGTAAGAAGATAATCCTTACATTATTTGTACTACCATTTCCAATTATGGTATG
+GGGAGTTATGACGCAAGGTTGGTGGTTCCCAGTTATGGCTTCAGCATTTTTAATATTTAC
+AATTATAATAATGTTTATTGCTGGGACAGGTAAATCTGGATTGGGAGAAAAAGGAACTGT
+AGATGCATTTGTCAATGGTGCATCAAGTTTAGTAGGTGTATCTTTAATTATTGGTTTAGC
+TCGAGGTATTAATTTAGTGTTGAATGAAGGTATGATTTCAGATACAATCTTACACTTTTC
+ATCATCTTTAGTTCAACATATGAGTGGACCATTATTTATCATCGTATTACTATTTATTTT
+CTTCTGTTTAGGTTTTATCGTGCCATCATCTTCTGGATTAGCGGTATTATCAATGCCTAT
+CTTTGCACCACTAGCTGATACAGTAGGTATACCAAGATTCGTCATCGTTACGACATATCA
+ATTTGGTCAATATGCGATGTTATTCTTAGCGCCGACTGGACTTGTTATGGCCACACTACA
+AATGTTAAACATGCGATATTCACATTGGTTCCGATTTGTATGGCCGGTAGTTGCTTTTGT
+ATTGATTTTCGGTGGCGGAGTACTAATTACGCAAGTACTAATTTATTCATAATTTGAAAT
+GCTATATTATAAAAATACTAATTGGGTTTTATGCATCTCGTAGGTTTGTAGAAATACTAA
+ACTAAGCGAGGTGCATTATTATTTTTGATTAAGAAAATAATGACGGTAATGATAACACTA
+GTAAGTAATTGATACAATGCTCTATTTAATAATGATATTTTTAAAATTTGTTTTTAATGT
+AATGTTAGATCTATGGTATATTATATTTATCGTGGTAAATATGTATTTGCTGTAAACAGT
+TTTTGTAACACATGACACATATGGTTGTGAAAATAGCATATATAAAGGATGGCTATAAAT
+GACACATTTGACAAAGGTTTTAGATACACTAACTGGAATATGCGTAGTATTATTATTTAG
+TAAATATTTTGTGGCGTATGCAAATATGGTGTTTGATTGGAATTTAAGATGGTATTTGCT
+AGAAAACATACCACATTTGCCAATTATATTATTTATTCTGATGTTTATTTTCGGAGTACC
+TTCTGAAATGATAAAAGATAGGCAAAGGAAAAATAACGGTGTTTAATTTATCGATATTTA
+GAGGTGATAAAATTTGTCAACTATTACAAAGACTAAAATAAAAATCTTTATTAATTATTT
+TATTGGTATATTAGCCTTGGCGTTTGCTGCTTATATATTATTTAAATAAAGGTTAGAGTG
+AAACGTGTTTATGAACTAGACGTTCTAGTATAGTTACTACAGCTTTAGTCAGAAGGTATC
+ATTGATAAGATCATATTAAATCAAAGAGGCATTGATATACACTAAAAAGAGGCAAGATTA
+CCTGCCTCTTTTTTAGTTATTAAATATGCGTGTTAATTCTTGGTAATAGTGTTACTGAGA
+CGCATTACGAAGAAATTTATCTTGATTTTCCTTTTTTAAAAAGAAGTGAAGATATCCTAT
+AAAGACTCTAAGTACTATTACAGTGGCTAATAACACTTCGATAAACAAAAGACCTTTCCA
+AATATCTGGAAACATAAGTACAGGCAAACTGTTCTTTAAAGCAGTTGCTGAGATTACTAA
+AGGGAATGTGAAAGCTGAAAATACGGGCGAAAAAGGTTCTTTTAGTAATTTAGGCAATTG
+TATAATGATATAAAAATAAAATATTTGAGCTAATATTAAAAATATAATTACGATAAAAGC
+ATTCGCCTTAGGAAAGGCTATAACATATGCTGCAGCGACTAAAGAAAATGGTGCACAAAT
+TGTCGATGTGTTCGGTTTGATTGACGTCTGCAATGGAAATGCTTTTAATCGCTTGAAAAC
+AATAGGTAAGACAATACAAGTAGCTACAAAGCCATATATTACTGTTAATTGACCTATGAA
+AAAACATCCGCTAACGGGTGCCGTCAATCCTGCGATAGCAATACCAATAAAAAGTACAGT
+CCACGAAGGATAAACATTTTCAAGTGAAAAATCTTTTAAATATTTTATTGAAAAAATAAT
+CATATGCGTCATAATTCCCACAAGGCATAAAATCCAAATAGGCGTTATTAAGCTATTGAT
+AAAAGTTATGTTACTAAAAAATGTATTTAAATAAGTAGTACCTAAAAAGCCAGACATGAA
+AAATGTTGTGAACACTGATGAAACTAGAGGACTGTTTAATTGTTCTTTCACATTATTAAA
+ATATTTGATCATAGTACATAAAAGGTGAATCCAAATCAAGAAAGCAAAGATTCCGCAAAC
+AGCGTTTAAAGTAAGAGATAAGTCTTTTAATAGATTACCCAGGCCTAATAATCCTAAGAC
+TAGTCCTGACGTTACTAGAGGTGCTTTTTGAAGTCTCATGATTTACAACCTTTCTTATGT
+GATTTTCTTCACTAATTATATCATGATAGCTATGGCCAATTAATAAGAAGAGTGTGTACT
+ATTACGTTATTAGAGTATGTATATTGGATTGATAGACACATAATTGACATTTAAATCTCA
+AAATTAATGATATTTGAGGTATGCTTTGCAACCTAAATATTGGAATATGTGGAAAAGTAA
+TTATTTAATTTAAATGATGATTGAAGATTTACAAGGGGGTGTACAAAATGAGAAATCAAA
+TTCAAAAACTATTAGACAGTGATTTGAGCAGTTTACATATATCGAAACAAACAGGAGTTC
+CACAAAGCACAATACACAGAATGAGAAAAAAAGAAAGATCATTAGACAATATGTCATTGA
+AAAACGCTGAACTACTTTATAAATTTGCCAATAGTATATTTAGCAATGAAAATTAAGAAG
+AATAATTAGTGAGTTAAATAATTAAAAAACCACGTCTCGATGGACGTGGTTATTTTTTTA
+AATGTATTTAATTATAGGATTTCGGGCCCCTGAAAAGTCCCTAAAATTTTGAATAGTATC
+AAAATCTATAGGAATAATATAATAATAAAAATCTCTACGCATGCAAATGGTGAGTGTTAA
+AAATCTTGGTGTAGTGTTGGTGTAGTTCAGGTGCAGTATAGATGAAATTTGAGCACAAAA
+TTACTTAATTAAAAATGTATAAACAAGTGTCAGACGCGTGTCAATTGTGTGTCAAAAAAT
+TCTATGACGAATAAGCATGCTTGTTTTAATTACTGTATTTTCGGGGCTTATGCGGGGGAC
+GTTTTGGTGACGCATCATACTATATTACTGAAATTCAAAACAAAAAGAGCCCCGTAATCA
+CGGAACTCTTTTGTTTGGTAATGCGTATAAAAATACCTATAAACGTCCTGGGAGGGATTC
+GAACCCCCGACCGATGGCTTAGAAGGCCATTGCTCTATCCAGCTGAGCTACCAGGACACG
+TTTAACAACACAAGAATTATTATATCTAAATGAACTTAAATTAGCAATACCTTGTAAATA
+AAAAATGTTTATATTTTTCACTATTATAGAGCTATTTATCTAAAAAGGTTCAATAAGACT
+TAAATGCGAATTCAGGCAACTTAATTGTGTTAAATACAGTTTTGAATGCCTAACTGTATT
+TCTTTTCTCTTTAAAATACAGTTAAGTACATTATAAGATGTTGTGCGGATAAACAAACTA
+ATTGCATCAAATTTATTTTAAAATAACAACAACAAAACGTTAAGCGAATAACATTTCGGT
+GATTTAAAAGCTACGCACGTTTTTGTTATCTTCAAATTTAAATTTTAAGGAGTGTTTTCA
+ATGGAAGGTTTATTTAACGCAATTAAAGATACCGTAACTGCAGCAATTAATAATGATGGC
+GCAAAATTAGGCACAAGCATTGTGAGCATCGTTGAAAATGGCGTAGGTTTATTAGGTAAA
+TTATTCGGATTCTAATTTCAATATGTTATGTAAGTAATCAGTATTATTTCAAAGGTGAGG
+GAGAGATTTAAATGACTGGACTAGCAGAAGCAATCGCAAATACTGTGCAAGCTGCACAAC
+AACATGATAGTGTGAAATTAGGCACAAGTATCGTAGACATCGTTGCTAACGGTGTGGGTT
+TACTAGGTAAATTATTTGGATTCTAATATAATAACTAATATTCTTTAAAATAAACTGGGT
+GAGCATACTTTAATGTTATGCACTCAGTTTATTTTATTTGCAGAAATTTGAGCCTCTGTT
+AAGATTTAGATACATAGACAATATAGGAGATGGGGAAATTGGGATATAAAAATATTTTGA
+TAGACTTTGATGATACAATTGTTGATTTTTATGATGCAGAAGAATGGGCGTTTCACTATA
+TGGCGAATGTTTTTAATCATAAAGCAACAAAGGATGATTTTTTAACATTTAAAAAAATCA
+ATCACCAACATTGGGAAGCTTTTCAACAAAATAAATTAACGAAGTCTGAAGTATTATCAG
+AACGATTTGTGAATTACTTCAAACATCATCAAATGGAAGTTGATGGGCATCGTGCAGATG
+TGTTATTTAGAAATGGATTAGCAGAAGCTAAAGTTAAATACTTTGATCAAACATTAGAAA
+CAATTGTCGAATTATCGAAAAGACATGATTTATATATTGTTACTAATGGTGTAACCGAAA
+CGCAAAAGAGAAGGTTAAATCAGACGCCGTTGCATAAATATATTAAAAAGATATTTATAT
+CTGAGGAAACAGGATATCAAAAACCTAATCCGGAATTTTTTAATTATGTTTTTAATGATA
+TTGGTGAGGATGAAAGACAGCACTCGATTATAGTTGGAGATTCTTTAACATCTGACATTC
+TAGGTGGAATCAATGCGGGTATAGCTACTTGCTGGTTTAATTTTAGAGGATTTGATCATA
+ATCCAGGAATTATACCTGATTATGAAATTAATTCATGGAAACAACTAAATGATATTGTAC
+GTTAAGACAAATAATTTGAAAATGATTTATATTAGCTTAAGAAAGTAATTGTAAAAACGA
+CACTACGAAAAGATGCATTTTCATGCTCGTAGTGTCGAATATTATTATCTTATGGTTTCC
+ACAATAAGACATCATGTCCCTCTATATTTTTAGCTTCCACATCTGTAAATCCATGATGTA
+AAAAGAAATCCTTAGAATCATTTCTGCCAATGGCTTTAATTGGCATATTGAAACTCTTTG
+CAAAATCAATCAATTCTGAAGCGTACCCTCTGTTTTGATATTTTGGTAATACTTCTAACT
+TCCATAATAATATATAATCTTCAAAATCTGGGAAGTAGATTTCTTCGACATCACCTTTTT
+TTAGTAATGCCATTCTAGCTCCTAATTGATCTCCGACAAATATGCCATAAAATGGTGAAT
+CTGAACTTGCATCAATCATTTGACCGTTTAACTCATTGACCATGTATAAGTCTTTGTTGC
+CAAACGCTCTAAAGTTTTCGAATAATTCGTCAGTTTTGTAATTAATTTCAAGACGTTTGA
+TTTCACTCATATTTATCTACCCCTTATTTGTTTACTACTATTATTATACATTAAACCACT
+TGTGTTTTTCATTGATTTGAAAATGTAAAACAATGAACATTATAAATTTTCCATGATTAA
+ATTGATTTTCAAGCCGTAAAATTGTCAATCACCGGTATAGACTTTATACTATAGTTTGTA
+ATCGCGTACTTAAGGAGAAAAAACATGGACTGTAAAGTAGTTAGTTTAAATGAAAAAGAT
+CAGTTTATACCAAAAATAAAGAGCAGTGACCCTGTAATAACAGGATTATTTCAATATGAT
+GCAGCTCAACAAACTAGTTTTGAAAAAAGGATGTCTAAAGAAAATAATGGAAGAGAAGCG
+GCATTAGCGAATGTTATTCGTGAATATATGAGTGATTTAAAGCTTTCAAATGAACAAGAA
+TTAAACATACAACATTTAGCTAATGGTTCAAAAGTTGTGATTGGTGGACAACAAGCAGGG
+CTTTTCGGGGGACCATTGTATACATTCCATAAAATATTTTCAATCATTACTTTATCTAAG
+GAATTAACGGATACACATAAGCAACAAGTAGTACCAGTTTTTTGGATTGCAGGAGAAGAT
+CATGATTTCGATGAAGTGAATCATACATTTGTTTATAACGAAAATCATGGGTCGCTGCAT
+AAGGTTAAATATCATACAATGGAGATGCCAGAGACGACAGTCTCTAGATATTATCCTGAT
+AAGGCTGAGTTGAAACAAACTTTAAAAACGATGTTCATTCATATGAAAGAAACTGTTCAT
+ACACAAGGTCTACTGGAGATTTGTGACAGAATTATTGACCAATATGACTCGTGGACTGAT
+ATGTTTAAAGCACTACTGCATGAAACATTTAAAGCATATGGCGTTCTATTTATAGATGCG
+CAGTTTGAGCCGTTAAGAAAAATGGAAGCGCCTATGTTTAAAAAGATTTTGAAAAAACAT
+CAGTTGCTTGATGATGCTTTTAGAGCAACACAACAACGTACTCAAAATCAAGGCTTGAAT
+GCGATGATACAAACAGATACAAATGTTCATTTATTCTTACATGATGAAAATATGCGCCAA
+TTAGTTTCGTATGATGGTAAGCATTTTAAATTAAATAAAACAGATAAGACATATATAAAG
\ No newline at end of file
diff --git a/t/data/locus_tag_gffs/query_2.gff.proteome.faa.expected b/t/data/locus_tag_gffs/query_2.gff.proteome.faa.expected
new file mode 100644
index 0000000..4950fa7
--- /dev/null
+++ b/t/data/locus_tag_gffs/query_2.gff.proteome.faa.expected
@@ -0,0 +1,75 @@
+>zzz_00001
+MKTRIVSSVTTTLLLGSILMNPVANAADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGM
+HKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNE
+VAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFK
+TILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAAENFLDPN
+KASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKW
+TDRSSERYKIDWEKEEMTN*
+>zzz_00002
+MKLFYIVFLIIIWLNIFLGNEIIHTLTVLITTLYIVNSRKGIKNDRVE*
+>zzz_00003
+MTELNNIINSLQSLFESESGYKISKNSGVPYQTVQDLRNGKTKLEDARFRTIIKLYSYYV
+SLKEH*
+>zzz_00004
+MSKNITKNIILTTTLLLLGTVLPQNQKPVFSFYSEAKAYSIGQDETNINELIKYYTQPHF
+SFSNKWLYQYDNGNIYVELKRYSWSAHISLWGAESWGNINQLKDRYVDVFGLKDKDTDQL
+WWSYRETFTGGVTPAAKPSDKTYNLFVQYKDKLQTIIGAHKIYQGNKPVLTLKEIDFRAR
+EALIKNKILYTENRNKGKLKITGGGNNYTIDLSKRLHSDLANVYVKNPNKITVDVLFD*
+>zzz_00005
+MNNNITKKIILSTTLLLLGTAFTQFPNTPINSSSEAKAYYINQNETNVNELTKYYSQKYL
+TFSNSTLWQKDNGTIHATLLQFSWYSHIQVYGPESWGNINQLRNKSVDIFGIKDQETIDS
+FALSQETFTGGVTPAATSNDKHYKLNVTYKDKAETFTGGFPVYEGNKPVLTLKELDFRIR
+QTLIKSKKLYNNSYNKGQIKITGTDNNYTIDLSKRLPSTDANRYVKKPQNAKIEVILEKS
+N*
+>zzz_00006
+MKKNIMNKLVLSTALLLLGTTSTQLPKTPISFSSEAKAYNISENETNINELIKYYTQPHF
+SLSGKWLWQKPNGSIHATLQTWVWYSHIQVFGSESWGNINQLRNKYVDIFGTKDEDTVEG
+YWTYDETFTGGVTPAATSSDKPYRLFLKYSDKQQTIIGGHEFYKGNKPVLTLKELDFRIR
+QTLIKNKKLYNGEFNKGQIKITADGNNYTIDLSKKLKLTDTNRYVKNPKNAQIEVILEKS
+N*
+>zzz_00007
+MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTR
+CAFEVAAHDQGANVTYLGPTGSQMGKKETTKDTARVLGGMYDGIEYRGFSQRTVETLAEN
+SGVPVWNGLTDEDHPTQVLADFLTAKEVLKKDYADINFTYVGDGRNNVANALMQGAAIMG
+MNFHLVCPKELNPTDELLNRCKNIAAENGGNILITDDIDQGVKGSDVIYTDVWVSMGEPD
+EVWKERLELLKPYQVNKEMMDKTGNPNVIFEHCLPSFHNADTKIGQQIFEKYGIREMEVT
+DEVFESKASVVFQEAENRMHTIKAVMVATLGEF*
+>zzz_00008
+MMAKIVVALGGNALGKSPQEQLELVKNTAKSLVGLITKGHEIVISHGNGPQVGSINLGLN
+YAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVDENDPA
+FNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVPSPQPISIIELESIKTLIKN
+DTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDYVYINF
+NTENQQPLKTTNVDELKRYIDENQFAKGSMLPKIEAAISFIENNPKGSVLITSLNELDAA
+LEGKVGTVIKK*
+>zzz_01705
+VENTINESEKKKRFKLKMPGAFMILFILTVVAVIATWVIPAGAYSKLSYEPSSQELKIVN
+PHNQVKKVPGTQQELDKMGVKIKIEQFKSGAINKPVSIPNTYERLKQHPAGPEQITSSMV
+EGTIEAVDIMVFILVLGGLIGVVQASGSFESGLLALTKKTKGHEFMLIVFVSILMIIGGT
+LCGIEEEAVAFYPILVPIFIALGYDSIVSVGAIFLASSVGSTFSTINPFSVVIASNAAGT
+TFTDGLYWRIGACIVGAIFVISYLYWYCKKIKNDPKASYSYEDKDAFEQQWSVLKDDDSA
+HFTLRKKIILTLFVLPFPIMVWGVMTQGWWFPVMASAFLIFTIIIMFIAGTGKSGLGEKG
+TVDAFVNGASSLVGVSLIIGLARGINLVLNEGMISDTILHFSSSLVQHMSGPLFIIVLLF
+IFFCLGFIVPSSSGLAVLSMPIFAPLADTVGIPRFVIVTTYQFGQYAMLFLAPTGLVMAT
+LQMLNMRYSHWFRFVWPVVAFVLIFGGGVLITQVLIYS*
+>zzz_00010
+MTHLTKVLDTLTGICVVLLFSKYFVAYANMVFDWNLRWYLLENIPHLPIILFILMFIFGV
+PSEMIKDRQRKNNGV*
+>zzz_00011
+MRLQKAPLVTSGLVLGLLGLGNLLKDLSLTLNAVCGIFAFLIWIHLLCTMIKYFNNVKEQ
+LNSPLVSSVFTTFFMSGFLGTTYLNTFFSNITFINSLITPIWILCLVGIMTHMIIFSIKY
+LKDFSLENVYPSWTVLFIGIAIAGLTAPVSGCFFIGQLTVIYGFVATCIVLPIVFKRLKA
+FPLQTSIKPNTSTICAPFSLVAAAYVIAFPKANAFIVIIFLILAQIFYFYIIIQLPKLLK
+EPFSPVFSAFTFPLVISATALKNSLPVLMFPDIWKGLLFIEVLLATVIVLRVFIGYLHFF
+LKKENQDKFLRNASQ*
+>zzz_00012
+MRNQIQKLLDSDLSSLHISKQTGVPQSTIHRMRKKERSLDNMSLKNAELLYKFANSIFSN
+EN*
+>zzz_00014
+MEGLFNAIKDTVTAAINNDGAKLGTSIVSIVENGVGLLGKLFGF*
+>zzz_00015
+MTGLAEAIANTVQAAQQHDSVKLGTSIVDIVANGVGLLGKLFGF*
+>zzz_00016
+LGYKNILIDFDDTIVDFYDAEEWAFHYMANVFNHKATKDDFLTFKKINHQHWEAFQQNKL
+TKSEVLSERFVNYFKHHQMEVDGHRADVLFRNGLAEAKVKYFDQTLETIVELSKRHDLYI
+VTNGVTETQKRRLNQTPLHKYIKKIFISEETGYQKPNPEFFNYVFNDIGEDERQHSIIVG
+DSLTSDILGGINAGIATCWFNFRGFDHNPGIIPDYEINSWKQLNDIVR*
diff --git a/t/data/locus_tag_gffs/query_3.gff b/t/data/locus_tag_gffs/query_3.gff
new file mode 100644
index 0000000..b4b0cc0
--- /dev/null
+++ b/t/data/locus_tag_gffs/query_3.gff
@@ -0,0 +1,271 @@
+##gff-version 3
+##sequence-region abc|SC|contig000001 1 15000
+abc|SC|contig000001 Prodigal:2.60 CDS 172 1131 . - 0 gene=hly;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:Q2G1X0,protein motif:TIGRFAMs:TIGR01002,protein motif:Pfam:PF07968.6;locus_tag=xxx_00001;product=Alpha-toxin,beta-channel forming cytolysin,Leukocidin/Hemolysin toxin family protein;protein_id=gnl|SC|abc_00001
+abc|SC|contig000001 Prodigal:2.60 CDS 1804 1950 . + 0 inference=ab initio prediction:Prodigal:2.60;locus_tag=xxx_00002;product=hypothetical protein;protein_id=gnl|SC|abc_00002
+abc|SC|contig000001 Prodigal:2.60 CDS 1934 2131 . + 0 inference=ab initio prediction:Prodigal:2.60;locus_tag=xxx_00003;product=hypothetical protein;protein_id=gnl|SC|abc_00003
+abc|SC|contig000001 Prodigal:2.60 CDS 2621 3337 . - 0 inference=ab initio prediction:Prodigal:2.60,protein motif:CLUSTERS:PRK13350,protein motif:Pfam:PF02876.11;locus_tag=xxx_00004;product=superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00004
+abc|SC|contig000001 Prodigal:2.60 CDS 3445 4170 . - 0 gene=speH;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P0C0I6,protein motif:CLUSTERS:PRK13349,protein motif:Pfam:PF02876.11;locus_tag=xxx_00005;note=SPE H;product=hypothetical protein,superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00005
+abc|SC|contig000001 Prodigal:2.60 CDS 4265 4990 . - 0 inference=ab initio prediction:Prodigal:2.60,protein motif:CLUSTERS:PRK13043,protein motif:Pfam:PF02876.11;locus_tag=xxx_00006;product=superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00006
+abc|SC|contig000001 Prodigal:2.60 CDS 5428 6429 . + 0 eC_number=2.1.3.3;gene=argF;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P99073,protein motif:CLUSTERS:PRK04284,protein motif:Cdd:COG0078,protein motif:TIGRFAMs:TIGR00658,protein motif:Pfam:PF00185.1;locus_tag=xxx_00007;product=Ornithine carbamoyltransferase,ornithine carbamoyltransferase,Ornithine carbamoyltransferase,ornithine carbamoyltransferase,Aspartate/ornithine carbamoyltransferase%2C Asp/Orn b [...]
+abc|SC|contig000001 Prodigal:2.60 CDS 6449 7384 . + 0 eC_number=2.7.2.2;gene=arcC1;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:Q7A627,protein motif:CLUSTERS:PRK12353,protein motif:TIGRFAMs:TIGR00746,protein motif:Pfam:PF00696.22;locus_tag=xxx_00008;product=Carbamate kinase 1,putative amino acid kinase,carbamate kinase,Amino acid kinase family protein;protein_id=gnl|SC|abc_00008
+abc|SC|contig000001 RNAmmer:1.2 rRNA 7556 9112 . + 0 inference=COORDINATES:profile:RNAmmer:1.2;locus_tag=xxx_01705;product=16S ribosomal RNA
+abc|SC|contig000001 Prodigal:2.60 CDS 9419 9646 . + 0 inference=ab initio prediction:Prodigal:2.60;locus_tag=xxx_00010;product=hypothetical protein;protein_id=gnl|SC|abc_00010
+abc|SC|contig000001 Prodigal:2.60 CDS 9952 10899 . - 0 inference=ab initio prediction:Prodigal:2.60,protein motif:Pfam:PF03595.11;locus_tag=xxx_00011;product=C4-dicarboxylate transporter/malic acid transport protein;protein_id=gnl|SC|abc_00011
+abc|SC|contig000001 Prodigal:2.60 CDS 11148 11336 . + 0 inference=ab initio prediction:Prodigal:2.60;locus_tag=xxx_00012;product=hypothetical protein;protein_id=gnl|SC|abc_00012
+abc|SC|contig000001 Aragorn:1.2.34 tRNA 11803 11878 . - 0 inference=COORDINATES:profile:Aragorn:1.2.34;locus_tag=xxx_00013;product=tRNA-Arg(tct)
+abc|SC|contig000001 Prodigal:2.60 CDS 12241 12375 . + 0 inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P11699,protein motif:Pfam:PF05480.5;locus_tag=xxx_00014;product=Gonococcal growth inhibitor III,Staphylococcus haemolytic protein;protein_id=gnl|SC|abc_00014
+abc|SC|contig000001 Prodigal:2.60 CDS 12432 12566 . + 0 inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P11699,protein motif:Pfam:PF05480.5;locus_tag=xxx_00015;product=Gonococcal growth inhibitor III,Staphylococcus haemolytic protein;protein_id=gnl|SC|abc_00015
+abc|SC|contig000001 Prodigal:2.60 CDS 12699 13385 . + 0 eC_number=3.-.-.-;gene=yfnB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:O06480,protein motif:CLUSTERS:PRK09449,protein motif:TIGRFAMs:TIGR02254,protein motif:Pfam:PF00702.1;locus_tag=xxx_00016;product=Putative HAD-hydrolase yfnB,dUMP phosphatase,HAD hydrolase,haloacid dehalogenase-like hydrolase;protein_id=gnl|SC|abc_00016
+##FASTA
+>abc|SC|contig000001
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
+ATACCCACCACATTTGGTGGAGAACCAAAAATTAGCCGAAAAACATCATTTCTGAAGTTA
+TCGGCTAAAGTTATAAATTATATTTATTTGTACATGAACAAATAATTTACATTAATTTGT
+CATTTCTTCTTTTTCCCAATCGATTTTATATCTTTCTGAAGAACGATCTGTCCATTTATC
+TTTAGTATTGGTACCTTTCCAATTTGTTGAAGTCCAATGCAATTGGTAGTCATCACGAAC
+TCGTTCGTATATTACATCTATATTTGTTTGTTGTTTGGATGCTTTTCTATCCATAGTAAT
+AACTGTAGCGAAGTCTGGTGAAAACCCTGAAGATAATAGAGAACTTGCTTTGTTAGGATC
+AAGGAAGTTCTCTGCTGCTTTCATAGAACCATTTCTAGTTTTCATGAAAAGTTGATTGCC
+ATATACCGGGTTCCAAGAATCTCTATCATATGGTCCCCAATTTTGATTCACCATATTGTT
+AAATATCACTTTCCAGCCTACTTTTTTATCAGTTGGGCTCTCTAAAATTGTTTTGAAATC
+AGGTTGAACATATTTCAGTGTATGACCAATCGAAACATTTGCACCAATAAGGCCGCCAAT
+TTTTCCTGTATCATCACCAGTAACATTACCGTTGAATCCATAAGTTAAAGTACTCATATA
+CTCTTTTGTATCAATCGAATTTCTTGGATAGTAATCAGATATTTGAGCTACTTCATTATC
+AGGTAGTTGCAACTGTACCTTAAAGGCTGAAGGCCAGGCTAAACCACTTTTGTTAGCACC
+TTCTTCGCTATAAACTCTATATTGACCAGCAATGGTACCTTTCGTTCTAATAACTAGCAG
+TTTTTTATTGTGATTTTTATCATCGATAAAACTATAAAATACTTTTTTGTGCATGCCATT
+TTCTTTATCATAAGTGACTAAATCACCTGTTTTTACTGTAGTATTGCTTCCAATATCTGT
+AGTACCGGTTTTAATATTAATATCAGAATCTGCGGCATTAGCGACAGGATTCATTAATAT
+GGAACCTAGCAATAGTGTTGTTGTTACTGAGCTGACTATACGTGTTTTCATTTTCATCAT
+CCTTCTATTTTTTTTAACGATTTGAGGAAACAATAATCAATATGTCAATTTAGAATATTG
+CAGTTGAGACATATCAAATATTTATAATCGTTTATATTAGTATATTTAATGTAGCAACTG
+ATAAATTACTGAGTGATGATGAGTGATTATTTTAAGAATATGTTTTTAACTTTTATTTAA
+AATTTGAAAGGAAGCATTTCAATTTCGAGGGTTAGTCAAAGTTGAATAAATTCTTTATGA
+AACAAGGAAAAGACATAGCTAATTTTATTGATTAATTTCTTTAAAACTAATGATTTGTTT
+GATTTAAAAATGTAATCGATTACAATATAAAAATACAAATATCTTAGAATTAAATCAATT
+AATTAACTATTAAATAAAAATTAAATATATATTAACTACTGTAAATTAATAAATAGAAAT
+AGAGAAAAAGGGTATTAATTATGTTTGGAATTTCGTCGGGAATAATTTTTGCCATTACAT
+AGAAATATCTAATAGATAATGAAAAAGTATCGTATGTATTTTTAATATAGTGTAAAATAT
+CATATGTAAAATAAAATGTAGATTTTTAGTTAGAGGCATTATAAGAAAATTTTGAGTATA
+GGTTAGCTTTTAATTATGAATCTTATTGAAATTTGATTAATAAATATATGATAGGGGATT
+AAAATGAAACTATTTTATATCGTATTTCTTATTATTATATGGCTGAATATATTTTTAGGA
+AATGAAATTATCCATACACTGACTGTTTTAATAACAACATTGTATATTGTTAATTCAAGA
+AAGGGGATTAAAAATGACAGAGTTGAATAATATTATAAACTCTCTTCAATCTTTGTTTGA
+GTCTGAATCAGGCTATAAAATTTCGAAAAATTCAGGAGTTCCATATCAAACAGTACAAGA
+TTTAAGAAATGGGAAAACCAAACTAGAAGATGCTAGATTTAGAACGATTATTAAACTTTA
+TAGTTACTATGTCTCATTAAAAGAACATTAATCATGGGACAATAAAGTATTGCTATAATA
+ATTGAATCATTAAATGAAGGAATAGAGCCTAAGACATAATAAATCAATGTCTTAGGCTCT
+ACAATATTATATTGGTAGTAGTTGACCGAATGAAAATGACCATGTAACAAGCATTTTTGG
+GGCCCCAACACAGAAGCTGACGAAAAGTCAGCTTACAATAATGTGCAAGTTGGGGATGGG
+CCCCAACACAGAGAATTTCAAAAAGAAATTCTACAGACAATGCAAGTTGGCGGGGCCCCA
+ACATAGAGAAATTCAAAAAGAAATTCTACAGACAATGCAAGTTGGGGAGTGACAACGAAA
+TAAATTTTATAAAATACCATTTCTGTCACATTCCTACTCCCAATTCCATTTAAATATATA
+GAAAATTTCACCTATTATATACATCATACACTTTAAAAATTATCATTTAAATAATCTGAT
+TTGGAATTAAAGTGCATGAAGTATAAGTCACCTTCATATACTAATCAAAGAGGACGTCAA
+CAGTTATTTTATTAGGATTTTTAACATAAACATTTGCTAGATCTGAATGTAATCTTTTGC
+TTAAATCAATAGTGTAGTTATTACCGCCACCGGTGATCTTAAGCTTACCTTTATTACGAT
+TTTCGGTATATAATATTTTATTTTTTATTAACGCTTCTCGTGCACGGAAATCGATTTCTT
+TCAATGTTAATACTGGTTTATTGCCTTGGTATATTTTATGCGCACCAATAATCGTTTGTA
+GTTTATCTTTGTATTGCACAAAAAGATTATAAGTTTTATCAGAAGGTTTTGCGGCTGGTG
+TAACGCCACCTGTAAATGTCTCTCTATAAGACCACCATAACTGATCAGTATCTTTGTCTT
+TTAGTCCAAACACATCTACGTAACGATCTTTTAACTGATTAATATTTCCCCAACTTTCAG
+CGCCCCATAAAGATATATGTGCTGACCATGAATATCTCTTAAGTTCAACATAAATGTTTC
+CATTATCATATTGATATAGCCATTTATTTGAAAATGAAAAATGAGGCTGTGTGTAATATT
+TAATTAATTCATTGATGTTAGTTTCATCTTGACCAATGCTATAAGCTTTAGCTTCAGAGT
+AAAAACTAAATACTGGTTTTTGATTTTGAGGTAATACAGTACCTAATAGTAATAATGTTG
+TCGTTAAAATTATATTTTTCGTGATGTTCTTACTCATTAGAACATCTCCTTTCAGAGGAA
+TCATGATACGAGGAATAAGAAATTTAAATGTGAGCGAAGTCAATATAGTATTTGCGATTA
+TTTTTATTAACTCCATTATTATTGTTAGTTTGATTTTTCGAGGATAACTTCAATTTTTGC
+ATTTTGAGGTTTTTTAACATATCTATTTGCATCAGTTGATGGCAACCTTTTACTTAAATC
+TATTGTGTAGTTATTGTCTGTACCTGTTATTTTAATTTGTCCTTTATTATAAGAATTATT
+ATATAATTTTTTACTTTTAATTAATGTTTGACGAATACGAAAATCTAATTCTTTTAAAGT
+TAAAACAGGCTTATTGCCTTCATAAACTGGAAATCCGCCAGTAAACGTTTCTGCTTTATC
+TTTATATGTTACATTCAGTTTATAGTGTTTATCGTTAGATGTTGCTGCAGGAGTAACACC
+ACCAGTAAACGTTTCTTGAGATAATGCAAAAGAATCAATGGTTTCTTGGTCTTTTATGCC
+AAAAATATCAACGCTTTTATTTCTTAATTGGTTGATATTGCCCCAACTTTCAGGTCCATA
+AACTTGAATATGACTATACCAAGAAAACTGTAACAACGTTGCATGAATCGTACCGTTATC
+TTTTTGCCATAACGTACTGTTAGAGAAGGTTAAATATTTTTGCGAGTAATATTTAGTTAA
+CTCATTAACGTTAGTTTCGTTTTGATTTATATAATAAGCTTTCGCTTCAGATGAAGAATT
+GATAGGTGTATTAGGAAATTGTGTAAATGCTGTACCTAATAGTAACAATGTTGTTGATAA
+AATAATTTTTTTCGTGATGTTATTGTTCATTCGAATTTCTCCTTTGAGTATTGTTGGAAT
+GTTTAATTATAAAAAGGGGTTAATTAGATAATTGAAATTATCCGCATTTACAAAAGGTAA
+TAGGTTAGTTAGATTTTTCGAGTATGACTTCAATTTGTGCATTTTTAGGATTTTTAACAT
+AACGGTTTGTGTCAGTTAATTTTAACTTTTTACTTAAATCAATCGTGTAATTATTTCCAT
+CAGCAGTTATCTTAATTTGACCTTTATTAAATTCTCCGTTATATAACTTTTTATTCTTTA
+TTAATGTTTGACGAATACGGAAATCTAATTCTTTTAAAGTTAATACTGGTTTATTTCCTT
+TGTAAAATTCATGTCCACCGATGATAGTTTGTTGTTTATCACTATATTTTAAAAATAGTC
+TATAAGGTTTATCAGATGAAGTAGCTGCTGGCGTAACACCACCAGTAAATGTTTCATCAT
+AAGTCCAGTAACCTTCAACTGTGTCCTCATCTTTAGTTCCAAATATATCAACGTATTTAT
+TTCTTAACTGATTAATGTTTCCCCAACTCTCGGATCCAAACACTTGAATATGACTATACC
+AAACCCACGTTTGCAATGTTGCATGAATGCTACCATTGGGCTTTTGCCATAGCCATTTTC
+CAGATAATGAAAAATGCGGCTGAGTGTAATATTTGATTAACTCATTGATATTAGTCTCGT
+TTTCACTGATATTATAGGCTTTTGCTTCAGATGAAAAACTGATTGGTGTTTTAGGAAGTT
+GTGTTGATGTGGTTCCTAAAAGTAACAATGCTGTTGATAAAACTAATTTATTCATGATGT
+TCTTTTTCATATGAAAATCTCCTTTGCGTGAATTACCCAAAGTATATAAGCTATTACACC
+GATTCGGAATTAAATAAAAGCTAAAACTATGTTAAATAAACTTAAACAGTTAGTAGTGTT
+ATTTAAGCAAAACTTATCATTTTTAAGTTTTGGACAGAAACAGTACTTAATAAAGTAGGC
+GGGAGTTATATATTAAAAACGACACGTTACAATTATTCTCTAATCAATTGCATTAAATTG
+TTTGATAATTGAATTTTCTAACTACTTGAAAAATAGTTATACTTTAAATGTAGTACTTAT
+TTTAATTATTTCCTACTACTTAAATTTAATATTAATAAAATGTTCATTTAATTATTGATA
+AAATATTACAAATTTTAATAGTAGGTTGTGTTTATTTTGTATGCGCTTACAATTTAGGTG
+TAACTAAAATAAAAGGAGTTGTTATTAATGAAAAATTTACGAAACAGAAGTTTTTTAACT
+TTATTAGACTTTTCACGACAAGAGGTAGAATTCTTATTAACACTCTCCGAGGATTTAAAA
+CGTGCTAAATATATTGGCACTGAAAAGCCTATGTTAAAAAATAAAAATATTGCACTGTTA
+TTTGAAAAAGATTCTACAAGAACGCGATGTGCATTTGAAGTTGCAGCGCATGATCAAGGT
+GCAAATGTAACTTATTTAGGCCCAACTGGATCACAAATGGGTAAAAAAGAAACAACTAAA
+GATACTGCACGTGTGCTTGGTGGAATGTATGATGGCATTGAATACCGTGGTTTTTCACAA
+AGAACAGTAGAAACTTTAGCTGAAAATTCAGGCGTACCAGTGTGGAATGGTTTAACTGAT
+GAAGATCATCCTACTCAAGTTCTTGCTGATTTCTTAACAGCAAAAGAAGTCTTAAAAAAA
+GATTATGCAGATATTAACTTTACATATGTTGGAGATGGTCGTAATAACGTTGCAAATGCA
+TTAATGCAAGGTGCTGCCATTATGGGTATGAACTTCCATTTAGTTTGTCCAAAAGAATTA
+AATCCAACAGATGAATTATTAAATCGCTGTAAAAATATTGCCGCTGAAAATGGTGGCAAC
+ATATTAATCACAGATGATATTGACCAAGGTGTAAAAGGTTCGGATGTAATTTACACTGAT
+GTTTGGGTATCAATGGGTGAACCTGATGAAGTATGGAAAGAACGACTTGAATTATTGAAA
+CCATATCAAGTAAATAAAGAAATGATGGATAAAACTGGTAATCCAAATGTTATTTTTGAG
+CATTGCTTACCATCTTTCCATAATGCTGATACGAAAATTGGTCAACAAATTTTTGAAAAA
+TATGGTATTCGAGAAATGGAAGTTACAGATGAAGTATTCGAAAGTAAAGCTTCAGTTGTA
+TTCCAAGAAGCTGAGAACAGAATGCATACAATCAAAGCAGTCATGGTTGCTACATTGGGT
+GAATTTTAAATGATATAAGGAAGTGAATATGATGGCGAAAATAGTAGTAGCATTAGGTGG
+TAATGCTTTAGGAAAATCACCTCAAGAACAACTCGAGCTTGTTAAAAATACTGCGAAATC
+ATTAGTAGGATTAATAACAAAAGGACATGAGATTGTTATTAGTCATGGTAATGGACCACA
+GGTTGGAAGCATTAATTTGGGACTTAACTATGCTGCAGAACATAACCAAGGTCCGGCATT
+TCCATTTGCTGAATGTGGCGCAATGAGTCAAGCTTACATCGGCTATCAATTACAAGAAAG
+CTTACAAAATGAATTGCATTCTATTGGAATGGATAAACAAGTGGTAACACTAGTGACACA
+AGTTGAAGTTGATGAAAATGATCCGGCATTTAACAATCCTTCAAAACCAATTGGGTTATT
+TTACAACAAAGAAGAAGCTGAACAAATTCAAAAAGAAAAAGGATTTATATTTGTTGAAGA
+TGCTGGAAGAGGATATAGACGCGTTGTTCCTTCACCACAACCCATCTCTATTATTGAATT
+AGAGAGTATTAAAACACTTATTAAAAATGATACACTCGTTATTGCTGCTGGTGGTGGAGG
+TATACCAGTAATTAGAGAGCAACATGATGGTTTTAAAGGTATTGATGCAGTTATAGACAA
+AGATAAAACAAGTGCGTTGTTGGGTGCTAATATTCAATGCGATCAATTGATTATTTTAAC
+AGCAATTGATTATGTATATATTAATTTTAACACTGAAAACCAACAGCCTTTGAAAACAAC
+AAATGTTGATGAATTAAAACGATATATAGACGAAAATCAATTTGCAAAAGGAAGTATGTT
+ACCAAAAATTGAAGCAGCCATATCATTTATTGAAAACAATCCAAAAGGAAGTGTGCTTAT
+AACATCATTAAATGAATTAGATGCTGCCTTAGAGGGTAAAGTAGGTACTGTGATTAAAAA
+GTAATTGAATTGAAACGCTTTTCAATTACTATATGTCAAATGCATGATTTTTATTATTTA
+TGTGCACCCCCTGAAAATAATGCCTCTATTTTGATGCGGGGTGCACTTTCTTAATTTATA
+TTTATAAAATCTTTAAGGTAGAAATGCTAGGTTAAATGTCGAAGGAGATGAAACCGTGGA
+AAATACAATTAATGAAAGTGAAAAGAAAAAACGATTTAAATTAAAAATGCCAGGTGCATT
+TATGATTTTATTCATTTTAACGGTTGTTGCAGTTATAGCAACATGGGTTATTCCTGCTGG
+TGCATATTCTAAACTTTCTTACGAACCTTCATCCCAAGAACTAAAGATAGTTAACCCTCA
+TAACCAAGTGAAAAAGGTTCCGGGTACGCAACAGGAACTAGACAAAATGGGGGTTAAAAT
+TAAGATTGAACAATTTAAATCAGGTGCAATTAATAAGCCAGTATCAATTCCGAATACTTA
+TGAAAGATTAAAGCAACATCCAGCTGGACCAGAACAAATAACAAGTAGCATGGTTGAAGG
+TACGATAGAAGCGGTCGATATCATGGTATTCATTCTTGTACTAGGGGGACTTATTGGCGT
+AGTTCAAGCCAGTGGTTCTTTTGAATCGGGATTGTTAGCTTTAACGAAGAAAACAAAAGG
+GCATGAATTTATGCTAATTGTGTTTGTATCAATACTAATGATTATCGGCGGGACGTTATG
+TGGTATTGAAGAAGAAGCTGTAGCATTCTATCCGATTTTAGTCCCTATATTTATAGCGTT
+AGGATACGATTCTATCGTTTCAGTTGGTGCCATATTCCTTGCCAGCTCTGTCGGTAGTAC
+ATTTTCAACTATTAACCCGTTCTCGGTTGTAATTGCCTCTAATGCCGCTGGTACAACTTT
+TACGGATGGCTTGTATTGGAGAATAGGTGCTTGTATTGTCGGTGCGATTTTTGTTATTAG
+TTATTTATATTGGTACTGTAAAAAAATTAAAAACGATCCTAAAGCGTCATATTCTTATGA
+AGACAAAGATGCTTTTGAACAGCAATGGTCTGTATTAAAAGATGACGATAGTGCCCATTT
+TACTTTGCGTAAGAAGATAATCCTTACATTATTTGTACTACCATTTCCAATTATGGTATG
+GGGAGTTATGACGCAAGGTTGGTGGTTCCCAGTTATGGCTTCAGCATTTTTAATATTTAC
+AATTATAATAATGTTTATTGCTGGGACAGGTAAATCTGGATTGGGAGAAAAAGGAACTGT
+AGATGCATTTGTCAATGGTGCATCAAGTTTAGTAGGTGTATCTTTAATTATTGGTTTAGC
+TCGAGGTATTAATTTAGTGTTGAATGAAGGTATGATTTCAGATACAATCTTACACTTTTC
+ATCATCTTTAGTTCAACATATGAGTGGACCATTATTTATCATCGTATTACTATTTATTTT
+CTTCTGTTTAGGTTTTATCGTGCCATCATCTTCTGGATTAGCGGTATTATCAATGCCTAT
+CTTTGCACCACTAGCTGATACAGTAGGTATACCAAGATTCGTCATCGTTACGACATATCA
+ATTTGGTCAATATGCGATGTTATTCTTAGCGCCGACTGGACTTGTTATGGCCACACTACA
+AATGTTAAACATGCGATATTCACATTGGTTCCGATTTGTATGGCCGGTAGTTGCTTTTGT
+ATTGATTTTCGGTGGCGGAGTACTAATTACGCAAGTACTAATTTATTCATAATTTGAAAT
+GCTATATTATAAAAATACTAATTGGGTTTTATGCATCTCGTAGGTTTGTAGAAATACTAA
+ACTAAGCGAGGTGCATTATTATTTTTGATTAAGAAAATAATGACGGTAATGATAACACTA
+GTAAGTAATTGATACAATGCTCTATTTAATAATGATATTTTTAAAATTTGTTTTTAATGT
+AATGTTAGATCTATGGTATATTATATTTATCGTGGTAAATATGTATTTGCTGTAAACAGT
+TTTTGTAACACATGACACATATGGTTGTGAAAATAGCATATATAAAGGATGGCTATAAAT
+GACACATTTGACAAAGGTTTTAGATACACTAACTGGAATATGCGTAGTATTATTATTTAG
+TAAATATTTTGTGGCGTATGCAAATATGGTGTTTGATTGGAATTTAAGATGGTATTTGCT
+AGAAAACATACCACATTTGCCAATTATATTATTTATTCTGATGTTTATTTTCGGAGTACC
+TTCTGAAATGATAAAAGATAGGCAAAGGAAAAATAACGGTGTTTAATTTATCGATATTTA
+GAGGTGATAAAATTTGTCAACTATTACAAAGACTAAAATAAAAATCTTTATTAATTATTT
+TATTGGTATATTAGCCTTGGCGTTTGCTGCTTATATATTATTTAAATAAAGGTTAGAGTG
+AAACGTGTTTATGAACTAGACGTTCTAGTATAGTTACTACAGCTTTAGTCAGAAGGTATC
+ATTGATAAGATCATATTAAATCAAAGAGGCATTGATATACACTAAAAAGAGGCAAGATTA
+CCTGCCTCTTTTTTAGTTATTAAATATGCGTGTTAATTCTTGGTAATAGTGTTACTGAGA
+CGCATTACGAAGAAATTTATCTTGATTTTCCTTTTTTAAAAAGAAGTGAAGATATCCTAT
+AAAGACTCTAAGTACTATTACAGTGGCTAATAACACTTCGATAAACAAAAGACCTTTCCA
+AATATCTGGAAACATAAGTACAGGCAAACTGTTCTTTAAAGCAGTTGCTGAGATTACTAA
+AGGGAATGTGAAAGCTGAAAATACGGGCGAAAAAGGTTCTTTTAGTAATTTAGGCAATTG
+TATAATGATATAAAAATAAAATATTTGAGCTAATATTAAAAATATAATTACGATAAAAGC
+ATTCGCCTTAGGAAAGGCTATAACATATGCTGCAGCGACTAAAGAAAATGGTGCACAAAT
+TGTCGATGTGTTCGGTTTGATTGACGTCTGCAATGGAAATGCTTTTAATCGCTTGAAAAC
+AATAGGTAAGACAATACAAGTAGCTACAAAGCCATATATTACTGTTAATTGACCTATGAA
+AAAACATCCGCTAACGGGTGCCGTCAATCCTGCGATAGCAATACCAATAAAAAGTACAGT
+CCACGAAGGATAAACATTTTCAAGTGAAAAATCTTTTAAATATTTTATTGAAAAAATAAT
+CATATGCGTCATAATTCCCACAAGGCATAAAATCCAAATAGGCGTTATTAAGCTATTGAT
+AAAAGTTATGTTACTAAAAAATGTATTTAAATAAGTAGTACCTAAAAAGCCAGACATGAA
+AAATGTTGTGAACACTGATGAAACTAGAGGACTGTTTAATTGTTCTTTCACATTATTAAA
+ATATTTGATCATAGTACATAAAAGGTGAATCCAAATCAAGAAAGCAAAGATTCCGCAAAC
+AGCGTTTAAAGTAAGAGATAAGTCTTTTAATAGATTACCCAGGCCTAATAATCCTAAGAC
+TAGTCCTGACGTTACTAGAGGTGCTTTTTGAAGTCTCATGATTTACAACCTTTCTTATGT
+GATTTTCTTCACTAATTATATCATGATAGCTATGGCCAATTAATAAGAAGAGTGTGTACT
+ATTACGTTATTAGAGTATGTATATTGGATTGATAGACACATAATTGACATTTAAATCTCA
+AAATTAATGATATTTGAGGTATGCTTTGCAACCTAAATATTGGAATATGTGGAAAAGTAA
+TTATTTAATTTAAATGATGATTGAAGATTTACAAGGGGGTGTACAAAATGAGAAATCAAA
+TTCAAAAACTATTAGACAGTGATTTGAGCAGTTTACATATATCGAAACAAACAGGAGTTC
+CACAAAGCACAATACACAGAATGAGAAAAAAAGAAAGATCATTAGACAATATGTCATTGA
+AAAACGCTGAACTACTTTATAAATTTGCCAATAGTATATTTAGCAATGAAAATTAAGAAG
+AATAATTAGTGAGTTAAATAATTAAAAAACCACGTCTCGATGGACGTGGTTATTTTTTTA
+AATGTATTTAATTATAGGATTTCGGGCCCCTGAAAAGTCCCTAAAATTTTGAATAGTATC
+AAAATCTATAGGAATAATATAATAATAAAAATCTCTACGCATGCAAATGGTGAGTGTTAA
+AAATCTTGGTGTAGTGTTGGTGTAGTTCAGGTGCAGTATAGATGAAATTTGAGCACAAAA
+TTACTTAATTAAAAATGTATAAACAAGTGTCAGACGCGTGTCAATTGTGTGTCAAAAAAT
+TCTATGACGAATAAGCATGCTTGTTTTAATTACTGTATTTTCGGGGCTTATGCGGGGGAC
+GTTTTGGTGACGCATCATACTATATTACTGAAATTCAAAACAAAAAGAGCCCCGTAATCA
+CGGAACTCTTTTGTTTGGTAATGCGTATAAAAATACCTATAAACGTCCTGGGAGGGATTC
+GAACCCCCGACCGATGGCTTAGAAGGCCATTGCTCTATCCAGCTGAGCTACCAGGACACG
+TTTAACAACACAAGAATTATTATATCTAAATGAACTTAAATTAGCAATACCTTGTAAATA
+AAAAATGTTTATATTTTTCACTATTATAGAGCTATTTATCTAAAAAGGTTCAATAAGACT
+TAAATGCGAATTCAGGCAACTTAATTGTGTTAAATACAGTTTTGAATGCCTAACTGTATT
+TCTTTTCTCTTTAAAATACAGTTAAGTACATTATAAGATGTTGTGCGGATAAACAAACTA
+ATTGCATCAAATTTATTTTAAAATAACAACAACAAAACGTTAAGCGAATAACATTTCGGT
+GATTTAAAAGCTACGCACGTTTTTGTTATCTTCAAATTTAAATTTTAAGGAGTGTTTTCA
+ATGGAAGGTTTATTTAACGCAATTAAAGATACCGTAACTGCAGCAATTAATAATGATGGC
+GCAAAATTAGGCACAAGCATTGTGAGCATCGTTGAAAATGGCGTAGGTTTATTAGGTAAA
+TTATTCGGATTCTAATTTCAATATGTTATGTAAGTAATCAGTATTATTTCAAAGGTGAGG
+GAGAGATTTAAATGACTGGACTAGCAGAAGCAATCGCAAATACTGTGCAAGCTGCACAAC
+AACATGATAGTGTGAAATTAGGCACAAGTATCGTAGACATCGTTGCTAACGGTGTGGGTT
+TACTAGGTAAATTATTTGGATTCTAATATAATAACTAATATTCTTTAAAATAAACTGGGT
+GAGCATACTTTAATGTTATGCACTCAGTTTATTTTATTTGCAGAAATTTGAGCCTCTGTT
+AAGATTTAGATACATAGACAATATAGGAGATGGGGAAATTGGGATATAAAAATATTTTGA
+TAGACTTTGATGATACAATTGTTGATTTTTATGATGCAGAAGAATGGGCGTTTCACTATA
+TGGCGAATGTTTTTAATCATAAAGCAACAAAGGATGATTTTTTAACATTTAAAAAAATCA
+ATCACCAACATTGGGAAGCTTTTCAACAAAATAAATTAACGAAGTCTGAAGTATTATCAG
+AACGATTTGTGAATTACTTCAAACATCATCAAATGGAAGTTGATGGGCATCGTGCAGATG
+TGTTATTTAGAAATGGATTAGCAGAAGCTAAAGTTAAATACTTTGATCAAACATTAGAAA
+CAATTGTCGAATTATCGAAAAGACATGATTTATATATTGTTACTAATGGTGTAACCGAAA
+CGCAAAAGAGAAGGTTAAATCAGACGCCGTTGCATAAATATATTAAAAAGATATTTATAT
+CTGAGGAAACAGGATATCAAAAACCTAATCCGGAATTTTTTAATTATGTTTTTAATGATA
+TTGGTGAGGATGAAAGACAGCACTCGATTATAGTTGGAGATTCTTTAACATCTGACATTC
+TAGGTGGAATCAATGCGGGTATAGCTACTTGCTGGTTTAATTTTAGAGGATTTGATCATA
+ATCCAGGAATTATACCTGATTATGAAATTAATTCATGGAAACAACTAAATGATATTGTAC
+GTTAAGACAAATAATTTGAAAATGATTTATATTAGCTTAAGAAAGTAATTGTAAAAACGA
+CACTACGAAAAGATGCATTTTCATGCTCGTAGTGTCGAATATTATTATCTTATGGTTTCC
+ACAATAAGACATCATGTCCCTCTATATTTTTAGCTTCCACATCTGTAAATCCATGATGTA
+AAAAGAAATCCTTAGAATCATTTCTGCCAATGGCTTTAATTGGCATATTGAAACTCTTTG
+CAAAATCAATCAATTCTGAAGCGTACCCTCTGTTTTGATATTTTGGTAATACTTCTAACT
+TCCATAATAATATATAATCTTCAAAATCTGGGAAGTAGATTTCTTCGACATCACCTTTTT
+TTAGTAATGCCATTCTAGCTCCTAATTGATCTCCGACAAATATGCCATAAAATGGTGAAT
+CTGAACTTGCATCAATCATTTGACCGTTTAACTCATTGACCATGTATAAGTCTTTGTTGC
+CAAACGCTCTAAAGTTTTCGAATAATTCGTCAGTTTTGTAATTAATTTCAAGACGTTTGA
+TTTCACTCATATTTATCTACCCCTTATTTGTTTACTACTATTATTATACATTAAACCACT
+TGTGTTTTTCATTGATTTGAAAATGTAAAACAATGAACATTATAAATTTTCCATGATTAA
+ATTGATTTTCAAGCCGTAAAATTGTCAATCACCGGTATAGACTTTATACTATAGTTTGTA
+ATCGCGTACTTAAGGAGAAAAAACATGGACTGTAAAGTAGTTAGTTTAAATGAAAAAGAT
+CAGTTTATACCAAAAATAAAGAGCAGTGACCCTGTAATAACAGGATTATTTCAATATGAT
+GCAGCTCAACAAACTAGTTTTGAAAAAAGGATGTCTAAAGAAAATAATGGAAGAGAAGCG
+GCATTAGCGAATGTTATTCGTGAATATATGAGTGATTTAAAGCTTTCAAATGAACAAGAA
+TTAAACATACAACATTTAGCTAATGGTTCAAAAGTTGTGATTGGTGGACAACAAGCAGGG
+CTTTTCGGGGGACCATTGTATACATTCCATAAAATATTTTCAATCATTACTTTATCTAAG
+GAATTAACGGATACACATAAGCAACAAGTAGTACCAGTTTTTTGGATTGCAGGAGAAGAT
+CATGATTTCGATGAAGTGAATCATACATTTGTTTATAACGAAAATCATGGGTCGCTGCAT
+AAGGTTAAATATCATACAATGGAGATGCCAGAGACGACAGTCTCTAGATATTATCCTGAT
+AAGGCTGAGTTGAAACAAACTTTAAAAACGATGTTCATTCATATGAAAGAAACTGTTCAT
+ACACAAGGTCTACTGGAGATTTGTGACAGAATTATTGACCAATATGACTCGTGGACTGAT
+ATGTTTAAAGCACTACTGCATGAAACATTTAAAGCATATGGCGTTCTATTTATAGATGCG
+CAGTTTGAGCCGTTAAGAAAAATGGAAGCGCCTATGTTTAAAAAGATTTTGAAAAAACAT
+CAGTTGCTTGATGATGCTTTTAGAGCAACACAACAACGTACTCAAAATCAAGGCTTGAAT
+GCGATGATACAAACAGATACAAATGTTCATTTATTCTTACATGATGAAAATATGCGCCAA
+TTAGTTTCGTATGATGGTAAGCATTTTAAATTAAATAAAACAGATAAGACATATATAAAG
\ No newline at end of file
diff --git a/t/data/locus_tag_gffs/query_3.gff.proteome.faa.expected b/t/data/locus_tag_gffs/query_3.gff.proteome.faa.expected
new file mode 100644
index 0000000..adcbe48
--- /dev/null
+++ b/t/data/locus_tag_gffs/query_3.gff.proteome.faa.expected
@@ -0,0 +1,75 @@
+>xxx_00001
+MKTRIVSSVTTTLLLGSILMNPVANAADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGM
+HKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNE
+VAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFK
+TILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAAENFLDPN
+KASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKW
+TDRSSERYKIDWEKEEMTN*
+>xxx_00002
+MKLFYIVFLIIIWLNIFLGNEIIHTLTVLITTLYIVNSRKGIKNDRVE*
+>xxx_00003
+MTELNNIINSLQSLFESESGYKISKNSGVPYQTVQDLRNGKTKLEDARFRTIIKLYSYYV
+SLKEH*
+>xxx_00004
+MSKNITKNIILTTTLLLLGTVLPQNQKPVFSFYSEAKAYSIGQDETNINELIKYYTQPHF
+SFSNKWLYQYDNGNIYVELKRYSWSAHISLWGAESWGNINQLKDRYVDVFGLKDKDTDQL
+WWSYRETFTGGVTPAAKPSDKTYNLFVQYKDKLQTIIGAHKIYQGNKPVLTLKEIDFRAR
+EALIKNKILYTENRNKGKLKITGGGNNYTIDLSKRLHSDLANVYVKNPNKITVDVLFD*
+>xxx_00005
+MNNNITKKIILSTTLLLLGTAFTQFPNTPINSSSEAKAYYINQNETNVNELTKYYSQKYL
+TFSNSTLWQKDNGTIHATLLQFSWYSHIQVYGPESWGNINQLRNKSVDIFGIKDQETIDS
+FALSQETFTGGVTPAATSNDKHYKLNVTYKDKAETFTGGFPVYEGNKPVLTLKELDFRIR
+QTLIKSKKLYNNSYNKGQIKITGTDNNYTIDLSKRLPSTDANRYVKKPQNAKIEVILEKS
+N*
+>xxx_00006
+MKKNIMNKLVLSTALLLLGTTSTQLPKTPISFSSEAKAYNISENETNINELIKYYTQPHF
+SLSGKWLWQKPNGSIHATLQTWVWYSHIQVFGSESWGNINQLRNKYVDIFGTKDEDTVEG
+YWTYDETFTGGVTPAATSSDKPYRLFLKYSDKQQTIIGGHEFYKGNKPVLTLKELDFRIR
+QTLIKNKKLYNGEFNKGQIKITADGNNYTIDLSKKLKLTDTNRYVKNPKNAQIEVILEKS
+N*
+>xxx_00007
+MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTR
+CAFEVAAHDQGANVTYLGPTGSQMGKKETTKDTARVLGGMYDGIEYRGFSQRTVETLAEN
+SGVPVWNGLTDEDHPTQVLADFLTAKEVLKKDYADINFTYVGDGRNNVANALMQGAAIMG
+MNFHLVCPKELNPTDELLNRCKNIAAENGGNILITDDIDQGVKGSDVIYTDVWVSMGEPD
+EVWKERLELLKPYQVNKEMMDKTGNPNVIFEHCLPSFHNADTKIGQQIFEKYGIREMEVT
+DEVFESKASVVFQEAENRMHTIKAVMVATLGEF*
+>xxx_00008
+MMAKIVVALGGNALGKSPQEQLELVKNTAKSLVGLITKGHEIVISHGNGPQVGSINLGLN
+YAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVDENDPA
+FNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVPSPQPISIIELESIKTLIKN
+DTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDYVYINF
+NTENQQPLKTTNVDELKRYIDENQFAKGSMLPKIEAAISFIENNPKGSVLITSLNELDAA
+LEGKVGTVIKK*
+>xxx_01705
+VENTINESEKKKRFKLKMPGAFMILFILTVVAVIATWVIPAGAYSKLSYEPSSQELKIVN
+PHNQVKKVPGTQQELDKMGVKIKIEQFKSGAINKPVSIPNTYERLKQHPAGPEQITSSMV
+EGTIEAVDIMVFILVLGGLIGVVQASGSFESGLLALTKKTKGHEFMLIVFVSILMIIGGT
+LCGIEEEAVAFYPILVPIFIALGYDSIVSVGAIFLASSVGSTFSTINPFSVVIASNAAGT
+TFTDGLYWRIGACIVGAIFVISYLYWYCKKIKNDPKASYSYEDKDAFEQQWSVLKDDDSA
+HFTLRKKIILTLFVLPFPIMVWGVMTQGWWFPVMASAFLIFTIIIMFIAGTGKSGLGEKG
+TVDAFVNGASSLVGVSLIIGLARGINLVLNEGMISDTILHFSSSLVQHMSGPLFIIVLLF
+IFFCLGFIVPSSSGLAVLSMPIFAPLADTVGIPRFVIVTTYQFGQYAMLFLAPTGLVMAT
+LQMLNMRYSHWFRFVWPVVAFVLIFGGGVLITQVLIYS*
+>xxx_00010
+MTHLTKVLDTLTGICVVLLFSKYFVAYANMVFDWNLRWYLLENIPHLPIILFILMFIFGV
+PSEMIKDRQRKNNGV*
+>xxx_00011
+MRLQKAPLVTSGLVLGLLGLGNLLKDLSLTLNAVCGIFAFLIWIHLLCTMIKYFNNVKEQ
+LNSPLVSSVFTTFFMSGFLGTTYLNTFFSNITFINSLITPIWILCLVGIMTHMIIFSIKY
+LKDFSLENVYPSWTVLFIGIAIAGLTAPVSGCFFIGQLTVIYGFVATCIVLPIVFKRLKA
+FPLQTSIKPNTSTICAPFSLVAAAYVIAFPKANAFIVIIFLILAQIFYFYIIIQLPKLLK
+EPFSPVFSAFTFPLVISATALKNSLPVLMFPDIWKGLLFIEVLLATVIVLRVFIGYLHFF
+LKKENQDKFLRNASQ*
+>xxx_00012
+MRNQIQKLLDSDLSSLHISKQTGVPQSTIHRMRKKERSLDNMSLKNAELLYKFANSIFSN
+EN*
+>xxx_00014
+MEGLFNAIKDTVTAAINNDGAKLGTSIVSIVENGVGLLGKLFGF*
+>xxx_00015
+MTGLAEAIANTVQAAQQHDSVKLGTSIVDIVANGVGLLGKLFGF*
+>xxx_00016
+LGYKNILIDFDDTIVDFYDAEEWAFHYMANVFNHKATKDDFLTFKKINHQHWEAFQQNKL
+TKSEVLSERFVNYFKHHQMEVDGHRADVLFRNGLAEAKVKYFDQTLETIVELSKRHDLYI
+VTNGVTETQKRRLNQTPLHKYIKKIFISEETGYQKPNPEFFNYVFNDIGEDERQHSIIVG
+DSLTSDILGGINAGIATCWFNFRGFDHNPGIIPDYEINSWKQLNDIVR*
diff --git a/t/data/locus_tag_gffs/query_5.gff b/t/data/locus_tag_gffs/query_5.gff
new file mode 100644
index 0000000..ad5d755
--- /dev/null
+++ b/t/data/locus_tag_gffs/query_5.gff
@@ -0,0 +1,271 @@
+##gff-version 3
+##sequence-region abc|SC|contig000001 1 15000
+abc|SC|contig000001 Prodigal:2.60 CDS 172 1131 . - 0 ID=3_1;gene=hly;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:Q2G1X0,protein motif:TIGRFAMs:TIGR01002,protein motif:Pfam:PF07968.6;locus_tag=ccc_00001;product=Alpha-toxin,beta-channel forming cytolysin,Leukocidin/Hemolysin toxin family protein;protein_id=gnl|SC|ccc_00001
+abc|SC|contig000001 Prodigal:2.60 CDS 1804 1950 . + 0 ID="ccc_50002";inference=ab initio prediction:Prodigal:2.60;locus_tag=ccc_00002;product=hypothetical protein;protein_id=gnl|SC|ccc_00002
+abc|SC|contig000001 Prodigal:2.60 CDS 1934 2131 . + 0 ID=ccc_50003;inference=ab initio prediction:Prodigal:2.60;locus_tag=ccc_00003;product=hypothetical protein;protein_id=gnl|SC|ccc_00003
+abc|SC|contig000001 Prodigal:2.60 CDS 2621 3337 . - 0 ID=ccc_50004;inference=ab initio prediction:Prodigal:2.60,protein motif:CLUSTERS:PRK13350,protein motif:Pfam:PF02876.11;locus_tag=ccc_00004;product=superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|ccc_00004
+abc|SC|contig000001 Prodigal:2.60 CDS 3445 4170 . - 0 ID=3_2;gene=speH;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P0C0I6,protein motif:CLUSTERS:PRK13349,protein motif:Pfam:PF02876.11;locus_tag=ccc_00005;note=SPE H;product=hypothetical protein,superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|ccc_00005
+abc|SC|contig000001 Prodigal:2.60 CDS 4265 4990 . - 0 ID="ccc_50006";inference=ab initio prediction:Prodigal:2.60,protein motif:CLUSTERS:PRK13043,protein motif:Pfam:PF02876.11;locus_tag=ccc_00006;product=superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|ccc_00006
+abc|SC|contig000001 Prodigal:2.60 CDS 5428 6429 . + 0 ID=3_3;eC_number=2.1.3.3;gene=argF;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P99073,protein motif:CLUSTERS:PRK04284,protein motif:Cdd:COG0078,protein motif:TIGRFAMs:TIGR00658,protein motif:Pfam:PF00185.1;locus_tag=ccc_00007;product=Ornithine carbamoyltransferase,ornithine carbamoyltransferase,Ornithine carbamoyltransferase,ornithine carbamoyltransferase,Aspartate/ornithine carbamoyltransferase%2C As [...]
+abc|SC|contig000001 Prodigal:2.60 CDS 6449 7384 . + 0 ID=ccc_50008;eC_number=2.7.2.2;gene=arcC1;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:Q7A627,protein motif:CLUSTERS:PRK12353,protein motif:TIGRFAMs:TIGR00746,protein motif:Pfam:PF00696.22;locus_tag=ccc_00008;product=Carbamate kinase 1,putative amino acid kinase,carbamate kinase,Amino acid kinase family protein;protein_id=gnl|SC|ccc_00008
+abc|SC|contig000001 RNAmmer:1.2 rRNA 7556 9112 . + 0 ID=ccc_51705;inference=COORDINATES:profile:RNAmmer:1.2;locus_tag=ccc_01705;product=16S ribosomal RNA
+abc|SC|contig000001 Prodigal:2.60 CDS 9419 9646 . + 0 ID=ccc_50010;inference=ab initio prediction:Prodigal:2.60;locus_tag=ccc_00010;product=hypothetical protein;protein_id=gnl|SC|ccc_00010
+abc|SC|contig000001 Prodigal:2.60 CDS 9952 10899 . - 0 ID=ccc_50011;inference=ab initio prediction:Prodigal:2.60,protein motif:Pfam:PF03595.11;locus_tag=ccc_00011;product=C4-dicarboxylate transporter/malic acid transport protein;protein_id=gnl|SC|ccc_00011
+abc|SC|contig000001 Prodigal:2.60 CDS 11148 11336 . + 0 ID=ccc_50012;inference=ab initio prediction:Prodigal:2.60;locus_tag=ccc_00012;product=hypothetical protein;protein_id=gnl|SC|ccc_00012
+abc|SC|contig000001 Aragorn:1.2.34 tRNA 11803 11878 . - 0 ID=ccc_50013;inference=COORDINATES:profile:Aragorn:1.2.34;locus_tag=ccc_00013;product=tRNA-Arg(tct)
+abc|SC|contig000001 Prodigal:2.60 CDS 12241 12375 . + 0 ID=ccc_50014;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P11699,protein motif:Pfam:PF05480.5;locus_tag=ccc_00014;product=Gonococcal growth inhibitor III,Staphylococcus haemolytic protein;protein_id=gnl|SC|ccc_00014
+abc|SC|contig000001 Prodigal:2.60 CDS 12432 12566 . + 0 ID="ccc_50015";inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P11699,protein motif:Pfam:PF05480.5;locus_tag=ccc_00015;product=Gonococcal growth inhibitor III,Staphylococcus haemolytic protein;protein_id=gnl|SC|ccc_00015
+abc|SC|contig000001 Prodigal:2.60 CDS 12699 13385 . + 0 ID=3_5;eC_number=3.-.-.-;gene=yfnB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:O06480,protein motif:CLUSTERS:PRK09449,protein motif:TIGRFAMs:TIGR02254,protein motif:Pfam:PF00702.1;locus_tag=ccc_00016;product=Putative HAD-hydrolase yfnB,dUMP phosphatase,HAD hydrolase,haloacid dehalogenase-like hydrolase;protein_id=gnl|SC|ccc_00016
+##FASTA
+>abc|SC|contig000001
+ACTGGCCGCCTAATTTTAAAAACTCCCCAAGCTGTAATTTAAGGGGGTTCTTTAAATTAT
+ATACCCACCACATTTTTTGGAGAACCCCAAACTAGCCGAAAAGGGGCATTTCTGAAGTTA
+ACGGCTAAAGTTATTTTTTATATTTCCCTGTCCATGAACAAAGGGGTTACATTAATTTGT
+AATTTCTTCTTTTTTTTAATCGATTCCCTATCTTTCTGAAGAGGGGTCTGTCCATTTATC
+ATTAGTATTGGTACTTTTCCAATTTCCCGAACTCCAATGCAAGGGGTAGTCATCACGAAC
+ACGTTCGTATATTATTTCTATATTTCCCTGTCGTTTGGATGCGGGGCTATCCATAGTAAT
+AACTGTAGCGAAGTTTTGTGAAAACCCCGAACATAATAGAGAGGGGGCTTTGTTAGGATC
+AAGGAAGTTCTCTGTTTCTTTCATACCCCCACTTCTAGTTTTGGGGAAAAGTTGATTGCC
+ATATACCGGGTTCCTTTAATCTCTACCCTATCGTCCCCAATTGGGGTTCACCATATTGTT
+AAATATCACTTTCCTTTCTACTTTTCCCTCACTTGGGCTCTCGGGGATTGTTTTGAAATC
+AGGTTGAACATATTTTTGTGTATGACCCATCCAAACATTTGCGGGGATAAGGCCGCCAAT
+ATTTCCTGTATCATTTTCAGTAACACCCCCGCTGAATCCATAGGGGAAAGTACTCATATA
+ATCTTTTGTATCAATTTAATTTCTTCCCTAGCAATCAGATATGGGGGCTACTTCATTATC
+AGGTAGTTGCAACTTTTCCTTAAAGCCCGAACGCCAGGCTAAGGGGCTTTTGTTAGCACC
+ATCTTCGCTATAAATTTTATATTGACCCGCACTGGTACCTTTGGGGCTAATAACTAGCAG
+ATTTTTATTGTGATTTTTATCATCGCCCAAACTATAAAATACGGGGTTGTGCATGCCATT
+ATCTTTATCATAAGTTTCTAAATCACCCGTTCTTACTGTAGTGGGGCTTCCAATATCTGT
+AGTACCGGTTTTAATTTTAATATCACCCTCTCCGGCATTAGCGGGGGGATTCATTAATAT
+AGAACCTAGCAATATTTTTGTTGTTCCCGAGCTGACTATACGGGGGTTCATTTTCATCAT
+ACTTCTATTTTTTTTTTCGATTTGACCCAACCATAATCAATAGGGGAATTTAGAATATTG
+AAGTTGAGACATATTTTATATTTATCCCCGTCTATATTAGTAGGGGTAATGTAGCAACTG
+ATAAATTACTGAGTTTTGATGAGTGCCCATTCTAAGAATATGGGGGTAACTTTTATTTAA
+AATTTGAAAGGAAGTTTTTCAATTTCCCGGGCTAGTCAAAGTGGGGTAAATTCTTTATGA
+AACAAGGAAAAGACTTTGCTAATTTCCCTGACTAATTTCTTTGGGGCTAATGATTTGTTT
+AATTTAAAAATGTATTTGATTACAACCCAAACATACAAATATGGGGGAATTAAATCAATT
+AATTAACTATTAAATTTAAATTAAACCCATACTAACTACTGTGGGGTAATAAATAGAAAT
+AGAGAAAAAGGGTATTTATTATGTTCCCAATCTCGTCGGGAAGGGGTTTTGCCATTACAT
+AGAAATATCTAATATTTAATGAAAACCCATCCTATGTATTTTGGGGATAGTGTAAAATAT
+AATATGTAAAATAATTTGTAGATTTCCCGTTCGAGGCATTATGGGGAAATTTTGAGTATA
+AGTTAGCTTTTAATTTTGAATCTTACCCAAACTTGATTAATAGGGGTATGATAGGGGATT
+AAAATGAAACTATTTTTTATCGTATCCCTTACTATTATATGGGGGGATATATTTTTAGGA
+AATGAAATTATCCATTTACTGACTGCCCTAACAACAACATTGGGGGTTGTTAATTCAAGA
+AAGGGGATTAAAAATTTCAGAGTTGCCCAATCTTATAAACTCGGGGCAATCTTTGTTTGA
+ATCTGAATCAGGCTTTTAAATTTCGCCCAATCCAGGAGTTCCGGGGCAAACAGTACAAGA
+ATTAAGAAATGGGATTTCCAAACTACCCGATCCTAGATTTAGGGGGATTATTAAACTTTA
+AAGTTACTATGTCTTTTTAAAAGAACCCTAACCATGGGACAAGGGGGTATTGCTATAATA
+ATTGAATCATTAAATTTAGGAATAGCCCCTACGACATAATAAGGGGATGTCTTAGGCTCT
+ACAATATTATATTGTTTGTAGTTGACCCAATCAAAATGACCAGGGGACAAGCATTTTTGG
+AGCCCCAACACAGATTTTGACGAAACCCCAGCTTACAATAATGGGGAAGTTGGGGATGGG
+ACCCAACACAGAGATTTTCAAAAAGCCCTTCCACAGACAATGGGGGTTGGCGGGGCCCCA
+ACATAGAGAAATTCTTTAAGAAATTCCCCAGCCAATGCAAGTGGGGGAGTGACAACGAAA
+AAAATTTTATAAAATTTCATTTCTGCCCCATCCCTACTCCCAGGGGCATTTAAATATATA
+AAAAATTTCACCTATTTTATACATCCCCCACCTTAAAAATTAGGGGTTAAATAATCTGAT
+ATGGAATTAAAGTGTTTGAAGTATACCCCACCTTCATATACTGGGGAAAGAGGACGTCAA
+AAGTTATTTTATTATTTTTTTTAACCCCAACCTTTGCTAGATGGGGATGTAATCTTTTGC
+ATAAATCAATAGTGTTTTTATTACCCCCACCCGTGATCTTAAGGGGACCTTTATTACGAT
+ATTCGGTATATAATTTTTTATTTTTCCCTAACGCTTCTCGTGGGGGGAAATCGATTTCTT
+ACAATGTTAATACTTTTTTATTGCCCCCGTACATTTTATGCGGGGGAATAATCGTTTGTA
+ATTTATCTTTGTATTTTACAAAAAGCCCATACGTTTTATCAGGGGGTTTTGCGGCTGGTG
+AAACGCCACCTGTATTTGTCTCTCTCCCAGACCACCATAACTGGGGAGTATCTTTGTCTT
+ATAGTCCAAACACATTTACGTAACGCCCTTTCAACTGATTAAGGGGTCCCCAACTTTCAG
+AGCCCCATAAAGATTTTTGTGCTGACCCTGACTATCTCTTAAGGGGAACATAAATGTTTC
+AATTATCATATTGATTTAGCCATTTCCCTGACAATGAAAAATGGGGCTGTGTGTAATATT
+AAATTAATTCATTGTTTTTAGTTTCCCCTTGCCCAATGCTATGGGGTTTAGCTTCAGAGT
+AAAAACTAAATACTTTTTTTTGATTCCCAGGCAATACAGTACGGGGTAGTAATAATGTTG
+ACGTTAAAATTATATTTTTCGTGATCCCCTTCCTCATTAGAAGGGGTCCTTTCAGAGGAA
+ACATGATACGAGGATTTAGAAATTTCCCTGTCAGCGAAGTCAGGGGAGTATTTGCGATTA
+ATTTTATTAACTCCTTTATTATTGTCCCTTTCATTTTTCGAGGGGGACTTCAATTTTTGC
+ATTTTGAGGTTTTTTTTCATATCTACCCGCACCAGTTGATGGGGGGCTTTTACTTAAATC
+AATTGTGTAGTTATTTTCTGTACCTCCCATTCTAATTTGTCCGGGGTTATAAGAATTATT
+ATATAATTTTTTACTTTTAATTAATCCCTGACGAATACGAAAGGGGAATTCTTTTAAAGT
+AAAAACAGGCTTATTTTCTTCATAACCCGGACATCCGCCAGTGGGGGTTTCTGCTTTATC
+ATTATATGTTACATTTTGTTTATAGCCCTTACCGTTAGATGTGGGGGCAGGAGTAACACC
+ACCAGTAAACGTTTTTTGAGATAATCCCAAACAATCAATGGTGGGGTGGTCTTTTATGCC
+AAAAATATCAACGCTTTTATTTCTTCCCTGGCTGATATTGCCGGGGCTTTCAGGTCCATA
+AACTTGAATATGACTTTACCAAGAACCCTGTCACAACGTTGCGGGGATCGTACCGTTATC
+ATTTTGCCATAACGTTTTGTTAGAGCCCGTTCAATATTTTTGGGGGTAATATTTAGTTAA
+ATCATTAACGTTAGTTTCGTTTTGACCCATACAATAAGCTTTGGGGTCAGATGAAGAATT
+AATAGGTGTATTAGTTTATTGTGTACCCGCTCTACCTAATAGGGGGAATGTTGTTGATAA
+AATAATTTTTTTCGTTTTGTTATTGCCCATTCGAATTTCTCCGGGGAGTATTGTTGGAAT
+ATTTAATTATAAAATTTGGTTAATTCCCTAACTGAAATTATCGGGGTTTACAAAAGGTAA
+AAGGTTAGTTAGATTTTTCGAGTATCCCTTCCATTTGTGCATGGGGAGGATTTTTAACAT
+AACGGTTTGTGTCATTTAATTTTAACCCTTTCCTTAAATCAAGGGGGTAATTATTTCCAT
+AAGCAGTTATCTTATTTTGACCTTTCCCAAACTCTCCGTTATGGGGCTTTTTATTCTTTA
+ATAATGTTTGACGATTTCGGAAATCCCCTTCCTTTAAAGTTAGGGGTGGTTTATTTCCTT
+AGTAAAATTCATGTTTTCCGATGATCCCTTGCTGTTTATCACGGGGTTTTAAAAATAGTC
+AATAAGGTTTATCATTTGAAGTAGCCCCTGGCGTAACACCACGGGGAAATGTTTCATCAT
+AAGTCCAGTAACCTTTTACTGTGTCCCCATCCTTAGTTCCAAGGGGATCAACGTATTTAT
+ATCTTAACTGATTATTTTTTCCCCACCCCTCCGATCCAAACAGGGGAATATGACTATACC
+AAACCCACGTTTGCTTTGTTGCATGCCCGCTCCCATTGGGCTGGGGCCATAGCCATTTTC
+AAGATAATGAAAAATTTGGCTGAGTCCCATACTTGATTAACTGGGGGATATTAGTCTCGT
+ATTCACTGATATTATTTGCTTTTGCCCCAGACGAAAAACTGAGGGGTGTTTTAGGAAGTT
+ATGTTGATGTGGTTTTTAAAAGTAACCCTGCCGTTGATAAAAGGGGTTTATTCATGATGT
+ACTTTTTCATATGATTTTCTCCTTTCCCTGACTTACCCAAAGGGGGTAAGCTATTACACC
+AATTCGGAATTAAATTTAAGCTAAACCCATGCTAAATAAACTGGGGCAGTTAGTAGTGTT
+ATTTAAGCAAAACTTTTCATTTTTACCCTTTCGACAGAAACAGGGGTTAATAAAGTAGGC
+AGGAGTTATATATTTTTAACGACACCCCACACTTATTCTCTAGGGGATTGCATTAAATTG
+ATTGATAATTGAATTTTCTAACTACCCCAAACATAGTTATACGGGGAATGTAGTACTTAT
+ATTAATTATTTCCTTTTACTTAAATCCCATACTAATAAAATGGGGGTTTAATTATTGATA
+AAATATTACAAATTTTTATAGTAGGCCCTGTCTATTTTGTATGGGGTTACAATTTAGGTG
+AAACTAAAATAAAATTTGTTGTTATCCCTGACAAATTTACGAGGGGGAAGTTTTTTAACT
+ATATTAGACTTTTCTTTACAAGAGGCCCAATCCTTATTAACAGGGGCCGAGGATTTAAAA
+AGTGCTAAATATATTTTCACTGAAACCCCTACGTTAAAAAATGGGGATATTGCACTGTTA
+ATTGAAAAAGATTCTTTAAGAACGCCCCGTGCATTTGAAGTTGGGGCGCATGATCAAGGT
+ACAAATGTAACTTATTTAGGCCCAACCCGATCACAAATGGGTGGGGAAGAAACAACTAAA
+AATACTGCACGTGTTTTTGGTGGAACCCATGCTGGCATTGAAGGGGGTGGTTTTTCACAA
+AGAACAGTAGAAACTTTAGCTGAAACCCCAGCCGTACCAGTGGGGGATGGTTTAACTGAT
+AAAGATCATCCTACTTTAGTTCTTGCCCATTCCTTAACAGCAGGGGAAGTCTTAAAAAAA
+AATTATGCAGATATTTTCTTTACATCCCTTGCAGATGGTCGTGGGGACGTTGCAAATGCA
+ATAATGCAAGGTGCTTTCATTATGGCCCTGACCTTCCATTTAGGGGGTCCAAAAGAATTA
+AATCCAACAGATGATTTATTAAATCCCCGTACAAATATTGCCGGGGAAAATGGTGGCAAC
+ATATTAATCACAGATTTTATTGACCCCCGTGCAAAAGGTTCGGGGGTAATTTACACTGAT
+ATTTGGGTATCAATTTTTGAACCTGCCCAAGCATGGAAAGAAGGGGTTGAATTATTGAAA
+ACATATCAAGTAAATTTAGAAATGACCCATACAACTGGTAATGGGGATGTTATTTTTGAG
+AATTGCTTACCATCTTTCCATAATGCCCATACGAAAATTGGTGGGGAAATTTTTGAAAAA
+AATGGTATTCGAGATTTGGAAGTTACCCATGCAGTATTCGAAGGGGAAGCTTCAGTTGTA
+ATCCAAGAAGCTGATTTCAGAATGCCCCCAACCAAAGCAGTCGGGGTTGCTACATTGGGT
+AAATTTTAAATGATTTTAGGAAGTGCCCATGCTGGCGAAAATGGGGGTAGCATTAGGTGG
+AAATGCTTTAGGAATTTCACCTCAACCCCAACTCGAGCTTGTGGGGAATACTGCGAAATC
+ATTAGTAGGATTAATTTCAAAAGGACCCGAGCTTGTTATTAGGGGGGGTAATGGACCACA
+AGTTGGAAGCATTATTTTGGGACTTCCCTATCCTGCAGAACAGGGGCAAGGTCCGGCATT
+ACCATTTGCTGAATTTTGCGCAATGCCCCAACCTTACATCGGGGGGCAATTACAAGAAAG
+ATTACAAAATGAATTTTATTCTATTCCCATGCATAAACAAGTGGGGACACTAGTGACACA
+AGTTGAAGTTGATGTTTATGATCCGCCCTTTCACAATCCTTCGGGGCCAATTGGGTTATT
+ATACAACAAAGAAGTTTCTGAACAACCCCAACAAGAAAAAGGGGGGATATTTGTTGAAGA
+AGCTGGAAGAGGATTTTGACGCGTTCCCCCTCCACCACAACCGGGGTCTATTATTGAATT
+AGAGAGTATTAAAATTTTTATTAAACCCGATCCACTCGTTATGGGGGCTGGTGGTGGAGG
+AATACCAGTAATTATTTAGCAACATCCCGGTCTTAAAGGTATGGGGGCAGTTATAGACAA
+AGATAAAACAAGTGTTTTGTTGGGTCCCAATCTTCAATGCGAGGGGTTGATTATTTTAAC
+AGCAATTGATTATGTTTATATTAATCCCAACCCTGAAAACCAGGGGCCTTTGAAAACAAC
+AAATGTTGATGAATTTTAACGATATCCCGACCAAAATCAATTGGGGAAAGGAAGTATGTT
+ACCAAAAATTGAAGTTTCCATATCACCCATTCAAAACAATCCGGGGGGAAGTGTGCTTAT
+AACATCATTAAATGTTTTAGATGCTCCCTTACAGGGTAAAGTGGGGACTGTGATTAAAAA
+ATAATTGAATTGAATTTCTTTTCAACCCCTACATGTCAAATGGGGGATTTTTATTATTTA
+AGTGCACCCCCTGATTTTAATGCCTCCCTTTCGATGCGGGGTGGGGTTTCTTAATTTATA
+ATTATAAAATCTTTTTTGTAGAAATCCCAGGCTAAATGTCGAGGGGGATGAAACCGTGGA
+AAATACAATTAATGTTTGTGAAAAGCCCAAACGATTTAAATTGGGGATGCCAGGTGCATT
+AATGATTTTATTCATTTTAACGGTTCCCGCACTTATAGCAACGGGGGTTATTCCTGCTGG
+AGCATATTCTAAACTTTCTTACGAACCCTCACCCCAAGAACTGGGGATAGTTAACCCTCA
+AAACCAAGTGAAAATTTTTCCGGGTCCCCAACAGGAACTAGAGGGGATGGGGGTTAAAAT
+AAAGATTGAACAATTTTAATCAGGTCCCATTCATAAGCCAGTGGGGATTCCGAATACTTA
+AGAAAGATTAAAGCTTTATCCAGCTCCCCCACAACAAATAACGGGGAGCATGGTTGAAGG
+AACGATAGAAGCGGTTTATATCATGCCCTTCCTTCTTGTACTGGGGGGACTTATTGGCGT
+AGTTCAAGCCAGTGTTTCTTTTGAACCCGGACTGTTAGCTTTGGGGAAGAAAACAAAAGG
+ACATGAATTTATGCTTTTTGTGTTTCCCTCACTACTAATGATGGGGGGCGGGACGTTATG
+AGGTATTGAAGAAGTTTCTGTAGCACCCTATCCGATTTTAGTGGGGATATTTATAGCGTT
+AGGATACGATTCTATTTTTTCAGTTCCCGCCCTATTCCTTGCGGGGTCTGTCGGTAGTAC
+ATTTTCAACTATTATTTCGTTCTCGCCCGTACTTGCCTCTAAGGGGGCTGGTACAACTTT
+AACGGATGGCTTGTTTTGGAGAATACCCGCTCGTATTGTCGGGGGGATTTTTGTTATTAG
+ATATTTATATTGGTTTTGTAAAAAACCCAAACACGATCCTAAGGGGTCATATTCTTATGA
+AGACAAAGATGCTTTTTAACAGCAACCCTCTCTATTAAAAGAGGGGGATAGTGCCCATTT
+AACTTTGCGTAAGATTTTAATCCTTCCCTTACTTGTACTACCGGGGCCAATTATGGTATG
+AGGAGTTATGACGCTTTGTTGGTGGCCCCCACTTATGGCTTCGGGGTTTTTAATATTTAC
+AATTATAATAATGTTTTTTGCTGGGCCCGGTCAATCTGGATTGGGGGAAAAAGGAACTGT
+AGATGCATTTGTCATTTGTGCATCACCCTTACTAGGTGTATCGGGGATTATTGGTTTAGC
+ACGAGGTATTAATTTTTTGTTGAATCCCGGTCTGATTTCAGAGGGGATCTTACACTTTTC
+ATCATCTTTAGTTCTTTATATGAGTCCCCCACTATTTATCATGGGGTTACTATTTATTTT
+ATTCTGTTTAGGTTTTTTCGTGCCACCCTCTCCTGGATTAGCGGGGTTATCAATGCCTAT
+ATTTGCACCACTAGTTTATACAGTACCCATACCAAGATTCGTGGGGGTTACGACATATCA
+ATTTGGTCAATATGTTTTGTTATTCCCCGCGCCGACTGGACTGGGGATGGCCACACTACA
+AATGTTAAACATGCTTTATTCACATCCCTTCCGATTTGTATGGGGGGTAGTTGCTTTTGT
+ATTGATTTTCGGTGTTTGAGTACTACCCACGCAAGTACTAATGGGGTCATAATTTGAAAT
+ACTATATTATAAAATTTCTAATTGGCCCTTACGCATCTCGTAGGGGTGTAGAAATACTAA
+ACTAAGCGAGGTGCTTTATTATTTTCCCTTACGAAAATAATGGGGGTAATGATAACACTA
+ATAAGTAATTGATATTTTGCTCTATCCCATACTGATATTTTTGGGGTTTGTTTTTAATGT
+AATGTTAGATCTATTTTATATTATACCCATCCTGGTAAATATGGGGTTGCTGTAAACAGT
+ATTTGTAACACATGTTTCATATGGTCCCGAACATAGCATATAGGGGGGATGGCTATAAAT
+AACACATTTGACAATTTTTTTAGATCCCCTACCTGGAATATGGGGGGTATTATTATTTAG
+AAAATATTTTGTGGTTTATGCAAATCCCGTGCTTGATTGGAAGGGGAGATGGTATTTGCT
+AGAAAACATACCACTTTTGCCAATTCCCTTACTTATTCTGATGGGGATTTTCGGAGTACC
+ATCTGAAATGATAATTTATAGGCAACCCAAACATAACGGTGTGGGGTTTATCGATATTTA
+AAGGTGATAAAATTTTTCAACTATTCCCAAGCCTAAAATAAAGGGGTTTATTAATTATTT
+AATTGGTATATTAGTTTTGGCGTTTCCCGCTCATATATTATTGGGGTAAAGGTTAGAGTG
+AAACGTGTTTATGATTTAGACGTTCCCCTATCGTTACTACAGGGGGAGTCAGAAGGTATC
+ATTGATAAGATCATTTTAAATCAAACCCGCACTGATATACACGGGGAAGAGGCAAGATTA
+ACTGCCTCTTTTTTTTTTATTAAATCCCCGTCTTAATTCTTGGGGGTAGTGTTACTGAGA
+AGCATTACGAAGAATTTTATCTTGACCCTCCCTTTTTAAAAAGGGGTGAAGATATCCTAT
+AAAGACTCTAAGTATTTTTACAGTGCCCAATCACACTTCGATGGGGAAAAGACCTTTCCA
+AATATCTGGAAACATTTGTACAGGCCCCCTGCTCTTTAAAGCGGGGGCTGAGATTACTAA
+AGGGAATGTGAAAGTTTAAAATACGCCCGAACAAGGTTCTTTGGGGAATTTAGGCAATTG
+AATAATGATATAAATTTAAAATATTCCCGCTCATATTAAAAAGGGGATTACGATAAAAGC
+ATTCGCCTTAGGAATTTCTATAACACCCGCTCCAGCGACTAAGGGGAATGGTGCACAAAT
+AGTCGATGTGTTCGTTTTGATTGACCCCTGCCATGGAAATGCGGGGAATCGCTTGAAAAC
+AATAGGTAAGACAATTTAAGTAGCTCCCAAGCCATATATTACGGGGAATTGACCTATGAA
+AAAACATCCGCTAATTTGTGCCGTCCCCCCTCCGATAGCAATGGGGATAAAAAGTACAGT
+ACACGAAGGATAAATTTTTTCAAGTCCCAAACCTTTTAAATAGGGGATTGAAAAAATAAT
+AATATGCGTCATAATTTCCACAAGGCCCAAACTCCAAATAGGGGGGATTAAGCTATTGAT
+AAAAGTTATGTTACTTTAAAATGTACCCAAACAAGTAGTACCGGGGAAGCCAGACATGAA
+AAATGTTGTGAACATTTATGAAACTCCCGGACTGTTTAATTGGGGGTTCACATTATTAAA
+ATATTTGATCATAGTTTATAAAAGGCCCATCCAAATCAAGAAGGGGAAGATTCCGCAAAC
+AGCGTTTAAAGTAATTTATAAGTCTCCCAATCGATTACCCAGGGGGAATAATCCTAAGAC
+AAGTCCTGACGTTATTTGAGGTGCTCCCTGACGTCTCATGATGGGGAACCTTTCTTATGT
+AATTTTCTTCACTATTTATATCATGCCCGCTCTGGCCAATTAGGGGGAAGAGTGTGTACT
+ATTACGTTATTAGATTTTGTATATTCCCTTGCTAGACACATAGGGGACATTTAAATCTCA
+AAATTAATGATATTTTTGGTATGCTCCCCAACCTAAATATTGGGGGATGTGGAAAAGTAA
+ATATTTAATTTAAATTTTGATTGAACCCTTACAAGGGGGTGTGGGGAATGAGAAATCAAA
+ATCAAAAACTATTATTTAGTGATTTCCCCAGCTTACATATATGGGGACAAACAGGAGTTC
+AACAAAGCACAATATTTAGAATGAGCCCAAACGAAAGATCATGGGGCAATATGTCATTGA
+AAAACGCTGAACTATTTTATAAATTCCCCAACAGTATATTTAGGGGTGAAAATTAAGAAG
+AATAATTAGTGAGTTTTATAATTAACCCACCCCGTCTCGATGGGGGTGGTTATTTTTTTA
+AATGTATTTAATTATTTGATTTCGGCCCCCTCAAAAGTCCCTGGGGTTTTGAATAGTATC
+AAAATCTATAGGAATTTTATAATAACCCAAACCTCTACGCATGGGGATGGTGAGTGTTAA
+AAATCTTGGTGTAGTTTTGGTGTAGCCCAGGCGCAGTATAGAGGGGATTTGAGCACAAAA
+ATACTTAATTAAAATTTTATAAACACCCGTCCGACGCGTGTCGGGGGTGTGTCAAAAAAT
+ACTATGACGAATAATTTTGCTTGTTCCCATTCCTGTATTTTCGGGGCTTATGCGGGGGAC
+ATTTTGGTGACGCATTTTACTATATCCCTGACATTCAAAACAGGGGGAGCCCCGTAATCA
+AGGAACTCTTTTGTTTTGTAATGCGCCCAAACATACCTATAAGGGGCCTGGGAGGGATTC
+AAACCCCCGACCGATTTCTTAGAAGCCCATTCCTCTATCCAGGGGGGCTACCAGGACACG
+ATTAACAACACAAGTTTTATTATATCCCAATCAACTTAAATTGGGGATACCTTGTAAATA
+AAAAATGTTTATATTTTTCACTATTCCCGAGCTATTTATCTAGGGGGGTTCAATAAGACT
+AAAATGCGAATTCATTTAACTTAATCCCGTTCAATACAGTTTGGGGTGCCTAACTGTATT
+ACTTTTCTCTTTAATTTACAGTTAACCCCATCATAAGATGTTGGGGGGATAAACAAACTA
+ATTGCATCAAATTTTTTTTAAAATACCCACACCAAAACGTTAGGGGAATAACATTTCGGT
+AATTTAAAAGCTACTTTCGTTTTTGCCCTCTCCAAATTTAAAGGGGAAGGAGTGTTTTCA
+ATGGAAGGTTTATTTTTCGCAATTACCCATACCGTAACTGCAGGGGTTAATAATGATGGC
+ACAAAATTAGGCACTTTCATTGTGACCCTCGCTGAAAATGGCGGGGGTTTATTAGGTAAA
+ATATTCGGATTCTATTTTCAATATGCCCTGTCAGTAATCAGTGGGGTTTCAAAGGTGAGG
+AAGAGATTTAAATGTTTGGACTAGCCCCAGCCATCGCAAATAGGGGGCAAGCTGCACAAC
+AACATGATAGTGTGTTTTTAGGCACCCCTATCGTAGACATCGGGGGTAACGGTGTGGGTT
+AACTAGGTAAATTATTTGGATTCTACCCTAACAACTAATATTGGGGAAAATAAACTGGGT
+AAGCATACTTTAATTTTATGCACTCCCCTTACTTTATTTGCAGGGGTTTGAGCCTCTGTT
+AAGATTTAGATACATTTACAATATACCCGATCGGGAAATTGGGGGGTAAAAATATTTTGA
+AAGACTTTGATGATTTTATTGTTGACCCTTACGATGCAGAAGGGGGGGCGTTTCACTATA
+AGGCGAATGTTTTTTTTCATAAAGCCCCAAACGATGATTTTTGGGGATTTAAAAAAATCA
+ATCACCAACATTGGTTTGCTTTTCACCCAAACAAATTAACGAGGGGTGAAGTATTATCAG
+AACGATTTGTGAATTTTTTCAAACACCCTCACATGGAAGTTGGGGGGCATCGTGCAGATG
+AGTTATTTAGAAATTTTTTAGCAGACCCTAACGTTAAATACTGGGGTCAAACATTAGAAA
+AAATTGTCGAATTATTTAAAAGACACCCTTTCTATATTGTTAGGGGTGGTGTAACCGAAA
+AGCAAAAGAGAAGGTTTAATCAGACCCCGTTCCATAAATATAGGGGAAAGATATTTATAT
+ATGAGGAAACAGGATTTCAAAAACCCCCTCCCGAATTTTTTAGGGGTGTTTTTAATGATA
+ATGGTGAGGATGAATTTCAGCACTCCCCTATCGTTGGAGATTGGGGAACATCTGACATTC
+AAGGTGGAATCAATTTTGGTATAGCCCCTTGCTGGTTTAATTGGGGAGGATTTGATCATA
+ATCCAGGAATTATATTTGATTATGACCCTAACTCATGGAAACGGGGAAATGATATTGTAC
+ATTAAGACAAATAATTTGAAAATGACCCATACTAGCTTAAGAGGGGAATTGTAAAAACGA
+AACTACGAAAAGATTTTTTTTCATGCCCGTACTGTCGAATATGGGGATCTTATGGTTTCC
+ACAATAAGACATCATTTCCCTCTATCCCTTTCGCTTCCACATGGGGAAATCCATGATGTA
+AAAAGAAATCCTTATTTTCATTTCTCCCAATCGCTTTAATTGGGGGATTGAAACTCTTTG
+AAAAATCAATCAATTTTGAAGCGTACCCTCTCTTTTGATATTGGGGTAATACTTCTAACT
+ACCATAATAATATATTTTCTTCAAACCCTGGCAAGTAGATTTGGGGGACATCACCTTTTT
+ATAGTAATGCCATTTTTGCTCCTAACCCATCCCCGACAAATAGGGGATAAAATGGTGAAT
+ATGAACTTGCATCATTTATTTGACCCCCTAACTCATTGACCAGGGGTAAGTCTTTGTTGC
+AAAACGCTCTAAAGTTTTCGAATAACCCGTCCGTTTTGTAATGGGGTTCAAGACGTTTGA
+ATTCACTCATATTTTTTTACCCCTTCCCTGTCTACTACTATTGGGGTACATTAAACCACT
+AGTGTTTTTCATTGTTTTGAAAATGCCCAACCATGAACATTAGGGGTTTTCCATGATTAA
+ATTGATTTTCAAGCTTTAAAATTGTCCCTCACCGGTATAGACGGGGTACTATAGTTTGTA
+ATCGCGTACTTAAGTTTAAAAAACACCCACTCTAAAGTAGTTGGGGTAAATGAAAAAGAT
+AAGTTTATACCAAATTTAAAGAGCACCCACCCTGTAATAACAGGGGTATTTCAATATGAT
+ACAGCTCAACAAACTTTTTTTGAAACCCGGACGTCTAAAGAAGGGGATGGAAGAGAAGCG
+ACATTAGCGAATGTTTTTCGTGAATCCCTGACTGATTTAAAGGGGGCAAATGAACAAGAA
+ATAAACATACAACATTTAGCTAATGCCCCAACAGTTGTGATTGGGGGACAACAAGCAGGG
+ATTTTCGGGGGACCTTTGTATACATCCCATACAATATTTTCAGGGGTTACTTTATCTAAG
+AAATTAACGGATACTTTTAAGCAACCCCTAGCACCAGTTTTTGGGGTTGCAGGAGAAGAT
+AATGATTTCGATGATTTGAATCATACCCTTGCTTATAACGAAGGGGATGGGTCGCTGCAT
+AAGGTTAAATATCATTTAATGGAGACCCCAGCGACGACAGTCGGGGGATATTATCCTGAT
+AAGGCTGAGTTGAATTTAACTTTAACCCCGACGTTCATTCATGGGGAAGAAACTGTTCAT
+ACACAAGGTCTACTTTTGATTTGTGCCCGAACTATTGACCAAGGGGACTCGTGGACTGAT
+ATGTTTAAAGCACTTTTGCATGAAACCCTTACAGCATATGGCGGGGTATTTATAGATGCG
+AAGTTTGAGCCGTTTTTAAAAATGGCCCCGCCTATGTTTAAAGGGGTTTTGAAAAAACAT
+AAGTTGCTTGATGATTTTTTTAGAGCCCCACCACAACGTACTGGGGATCAAGGCTTGAAT
+ACGATGATACAAACTTTTACAAATGCCCATTCATTCTTACATGGGGAAAATATGCGCCAA
+ATAGTTTCGTATGATTTTAAGCATTCCCAATCAAATAAAACAGGGGAGACATATATAAAG
\ No newline at end of file
diff --git a/t/data/locus_tag_gffs/query_5.gff.proteome.faa.expected b/t/data/locus_tag_gffs/query_5.gff.proteome.faa.expected
new file mode 100644
index 0000000..653afc3
--- /dev/null
+++ b/t/data/locus_tag_gffs/query_5.gff.proteome.faa.expected
@@ -0,0 +1,75 @@
+>3_1
+MNPRIVSSGTTKILLGSILMNPPANAGEGDIKIKTGTTDIGSPTTVRTGDLETYDKDNGM
+HNPVFYSLGDDKNHNKNLLVISPKGTSAGQYKIYSEDGANKSPLAWRSGFKEKLQLPDNE
+VAPISDC*GRN*IDTKDYMSTFPYGFSGGVTENDTGNIGGLIPANVWMGHTQKYVQPDFK
+TIPESPSEGKVERKVIFNNMVNPNWGR*GRD*RNPVYGNQLFPKTRSGGMKETENFLDPN
+KAPSLLCSGFSQNFATVITMDSPASKRQGNIEIIYERVRDDYPLHWSSGNWKSTNTNDKW
+TDPSSER*GID*KKEEITN*
+>ccc_50002
+MKLFFIVSLTIIWGDIFLGNEIIHLLTALTTTLGVVNSRKGIKNFRVAQ
+>ccc_50003
+ISELPNLINSGQSLFESESGF*ISPNPGVPGQTVQELRNGISKLPDPRFRGIIKL*SYYV
+FLKEP*
+>ccc_50004
+MRKGITKNIILTSTLLLPRTVLPGNQKKVFSFYSEAKPHSIGQGETKNNELI*YYTQPHF
+SLSGKWLNQYDN*NIYVPLKR*SGSAQKSLWGSESWGPLNQLKGRYVNVFGL*DKDTPQL
+WWSGRETNTGGVSPAAKPPDKTYGLFVKYKDKLQTIIPPHKMYGGNKKVLTL*EIDFPPR
+EALGKNKKLYTEYRNKGPLKITGGGNKNTIDLCKRLHPHLAKVGVKKNNKITFDVLFPQ
+>3_2
+MGNNKTKKIILSTTFPLLGRAGTQ*TNTPINSSSDPKAYCMGQNETNVNDLTKYYPQKY*
+TGSNKTLWQNDNGTIPATL*QGSW*SHIQVYGPESPGNISQGRNKSVDIFGIKDHPTIDC
+LGLSQKTFTGGVTPAPTSNGKGYKQNVTYNDKAETPTGGCPGYEENKPVFTLKEFPFRIR
+QGLIKSKKLYNNSYNPGQIRMGGTENNYTIDLSKSPPSTGAGRYEKKPQNAKIEVPLEK*
+KG
+>ccc_50006
+MKKYIMNKPLLSTAGLLLKTTST*LPKTPLSFSSGAKANNISEYETNIPQLIKYGTQPNF
+SLS*KWLWPQPNGSGHATKQTWVWYSHIPLFGSEGWGKNNQLRYKYVDPLGTKDGDTVKG
+YWTYDETFPRGVTPGATSNDKPY*LFLKPRDKQQGIIGKHEFY*GNKPPLTLKEGDFRNR
+QTLLKNKKPHNGEFGKGQNKITAYGNNYPLDLRKGLKLNDTNRYVKNPPHAQMEGILEKS
+N*
+>3_3
+LTNLRGGSFLTILDFSLQEAQSLLTGAEDLKSAKYIFTETPTLKNGDIALLIEKDSLRTP
+RAFEVGAHDQGTNVTYLGPTRSQMGGEETTKNTARVFGGTHAGIEGGGFSQRTVETLAET
+PAVPVGDGLTDKDHPTLVLAHSLTAGEVLKKNYADIFFTSLADGRGDVANAIMQGAFIMA
+LTFHLGGPKELNPTDDLLNPRTNIAGENGGNILITDFIDPRAKGSGVIYTDIWVSIFEPA
+QAWKEGVELLKTYQVNLEMTHTTGNGDVIFENCLPSFHNAHTKIGGEIFEKNGIRDLEVT
+HAVFEGEASVVIQEADFRMPPTKAVGVATLGKF*
+>ccc_50008
+MLAKMGVALGGNALGISPQPQLELVGNTAKSLVGLISKGPELVIRGGNGPQVGSIILGLP
+YPAEQGQGPALPFAEFCAMPQPYIGGQLQERLQNEFYSIPMHKQVGTLVTQVEVDVYDPP
+FHNPSGPIGLLYNKEVSEQPQQEKGGIFVEEAGRGF*RVPPPPQPGSIIELESIKIFIKP
+DPLVMGAGGGGIPVII*QHPGLKGMGAVIDKDKTSVLLGPNLQCEGLIILTAIDYVYINP
+NPENQGPLKTTNVDEF*RYPDQNQLGKGSMLPKIEVSISPIQNNPGGSVLITSLNVLDAP
+LQGKVGTVIKK*
+>ccc_51705
+VENTINVCEKPKRFKLGMPGALMILFILTVPALIATGVIPAGAYSKLSYEPSPQELGIVN
+PQNQVKIFPGPQQELEGMGVKIKIEQF*SGPIHKPVGIPNT*ERLKLYPAPPQQITGSMV
+EGTIEAVYIMPFLLVLGGLIGVVQASVSFEPGLLALGKKTKGHEFMLFVFPSLLMMGGGT
+L*GIEEVSVAPYPILVGIFIALGYDSIFSVPALFLAGSVGSTFSTIISFSPVLASKGAGT
+TLTDGLFWRIPARIVGGIFVIRYLYWFCKKPKHDPKGSYSYEDKDAF*QQPSLLKEGDSA
+HLTLRKILILPLLVLPGPIMV*GVMTLCWWPPLMASGFLIFTIIIMFFAGPGQSGLGEKG
+TVDAFVICASPLLGVSGIIGLARGINFLLNPGLISEGILHFSSSLVLYMSPPLFIMGLLF
+ILFCLGFFVPPSPGLAGLSMPIFAPLVYTVPIPRFVGVTTYQFGQYVLLFPAPTGLGMAT
+LQMLNMLYSHPFRFVWGVVAFVLIFGV*VLPTQVLMGS*
+>ccc_50010
+ITHLTIFLDPLPGIWGVLLFRKYFVVYANPVLDWKGRWYLLENIPLLPIPLLILMGIFGV
+PSEMIIYRQPKHNGVG
+>ccc_50011
+MRRQGAPQITSGLVLGLFPLGNRLGDL*ITLNAVCGIFPFLIWMGLL*TMIKYFNNVNPQ
+LNSPGVS*MFTTFFMSGFPGTTCLGTF*SNITFINSLIPPIWSLGLVEIMTHIIIFSIPY
+LKGLGLEKIYPSCTVLFIPIAIGGGTAQISGCFFIGQFPVIYGLGAT*IVLPIVFKRFPA
+FPWQGSIKTNTSTICAPFPLVAGAGVIEIPKANAFIVIPFLI*AGIF*IYIIIQLPKFPK
+EPCSGVF*TFTFPLVISAPALKSRGPVQMFPDIWKGLFPIEV*LGTVKILRVFIGYLHPF
+LKREGQDKILRNASQ*
+>ccc_50012
+MRNQNQKLLFSDFPSLHIWGQTGVQQSTIFRMSPNERSWGNMSLKNAELFYKFPNSIFRG
+EN*
+>ccc_50014
+MEGLFFAITHTVTAGVNNDGTKLGTFIVTLAENGGGLLGKIFGFY
+>ccc_50015
+MFGLAPAIANRGQAAQQHDSVFLGTPIVDIGGNGVG*LGKLFGFY
+>3_5
+LGGKNILKDFDDFIVDPYDAEGGAFHYKANVFFHKAPNDDFWGFKKINHQHWFAFHPNKL
+TRGEVLSERFVNFFKHPHMEVGGHRADELFRNFLADPNVKYWGQTLEKIVELFKRHPFYI
+VRGGVTEKQKRRFNQTPFHKYRGKIFIYEETGFQKPPPEFFRGVFNDNGEDEFQHSPIVG
+DWGTSDIQGGINFGIAPCWFNWGGFDHNPGIIFDYDPNSWKRGNDIVH*
diff --git a/t/data/mafft_input.fa b/t/data/mafft_input.fa
new file mode 100644
index 0000000..59c5769
--- /dev/null
+++ b/t/data/mafft_input.fa
@@ -0,0 +1,59 @@
+>1234_8#75_04759
+ATGAGCGAGCAGTTAACGGACCAGGTCCTGGTTGAACGGGTCCAGAAGGGAGATCAGAAA
+GCCTTTAACTTACTGGTAGTGCGCTACCAGCATAAAGTGGCGAGTCTGGTTTCCCGCTAT
+GTGCCATCGGGCGACGTTCCCGATGTCGTACAGGAATCATTTATTAAGGCCTATCGCGCG
+CTGGATTCTTTCCGGCGGGATAGTGCTTTTTATACCTGGTTGTATCGTATTGCGGTCAAT
+ACCGCGAAGAACTACCTGGTTGCGCAGGGGCGTCGTCCGCCTTCCAGTGATGTAGACGCG
+ATTGAAGCAGAAAACTTTGAAAGCGGCGGCGCGCTGAAAGAAATTTCGAACCCTGAGAAC
+TTAATGTTGTCAGAAGAACTGAGACAGATAGTTTTCCGAACTATTGAGTCCCTCCCGGAA
+GATTTACGTATGGCAATCACCTTACGGGAGCTGGATGGCCTGAGCTATGAAGAGATAGCG
+GCTATCATGGATTGTCCGGTGGGGACGGTGCGTTCACGTATCTTCCGGGCGCGGGAAGCT
+ATTGATAATAAAGTTCAACCGCTTATCAGGCGTTGA
+>1111#5_04506
+ATGGCAATCACCTTACGGGAGCTGGATGGCCTGAGCTATGAAGAGATAGCGGCTATCATG
+GATTGTCCGGTGGGGACGGTGCGTTCACGTATCTTCCGGGCGCGGGAAGCTATTGATAAT
+AAAGTTCAACCGCTTATCAGGCGTTGA
+>Salmonella_enterica_subsp_enterica_serovar_Typhimurium_DT104_v1_02853
+ATGAGCGAGCAGTTAACGGACCAGGTCCTGGTTGAACGGGTCCAGAAGGGAGATCAGAAA
+GCCTTTAACTTACTGGTAGTGCGCTACCAGCATAAAGTGGCGAGTCTGGTTTCCCGCTAT
+GTGCCATCGGGCGACGTTCCCGATGTCGTACAGGAATCATTTATTAAGGCCTATCGCGCG
+CTGGATTCTTTCCGGGGGGATAGTGCTTTTTATACCTGGTTGTATCGTATTGCGGTCAAT
+ACCGCGAAGAACTACCTGGTTGCGCAGGGGCGTCGTCCGCCTTCCAGTGATGTAGACGCG
+ATTGAAGCAGAAAACTTTGAAAGCGGCGGCGCGCTGAAAGAAATTTCGAACCCTGAGAAC
+TTAATGTTTTCAGAAGAACTGAGACAGATAGTTTTCCGAACTATTGAGTCCCTCCCGGAA
+GATTTACGTATGGCAATCACCTTACGGGAGCTGGATGGCCTGAGCTATGAAGAGATAGCG
+GCTATCATGGATTGTCCGGTGGGGACGGTGCGTTCACGTATCTTCCGGGCGCGGGAAGCT
+ATTGATAATAAAGTTCAACCGCTTATCAGGCGTTGA
+>Salmonella_enterica_subsp_enterica_serovar_Typhimurium_SL1344_v2_02736
+ATGAGCGAGCAGTTAACGGACCAGGTCCTGGTTGAACGGGTCCAGAAGGGAGATCAGAAA
+GCCTTTAACTTACTGGTAGTGCGCTACCAGCATAAAGTGGCGAGTCTGGTTTCCCGCTAT
+GTGCCATCGGGCGACGTTCCCGATGTCGTACAGGAATCATTTATTAAGGCCTATCGCGCG
+CTGGATTCTTTCCGGGGGGATAGTGCTTTTTATACCTGGTTGTATCGTATTGCGGTCAAT
+ACCGCGAAGAACTACCTGGTTGCGCAGGGGCGTCGTCCGCCTTCCAGTGATGTAGACGCG
+ATTGAAGCAGAAAACTTTGAAAGCGGCGGCGCGCTGAAAGAAATTTCGAACCCTGAGAAC
+TTAATGTTGTCAGAAGAACTGAGACAGATAGTTTTCCGAACTATTGAGTCCCTCCCGGAA
+GATTTACGTATGGCAATCACCTTACGGGAGCTGGATGGCCTGAGCTGTGAAGAGATAGCG
+GCTATCATGGATTGTCCGGTGGGGACGGTGCGTTCACGTATCTTCCGGGCGCGGGAAGCT
+ATTGATAATAAAGTTCAACCGCTTATCAGGCGTTGA
+>Salmonella_enterica_subsp_enterica_serovar_Typhimurium_str_D23580_v1_02783
+ATGAGCGAGCAGTTAACGGACCAGGTCCTGGTTGAACGGGTCCAGAAGGGAGATCAGAAA
+GCCTTTAACTTACTGGTAGTGCGCTACCAGCATAAAGTGGCGAGTCTGGTTTCCCGCTAT
+GTGCCATCGGGCGACGTTCCCGATGTCGTACAGGAATCATTTATTAAGGCCTATCGCGCG
+CTGGATTCTTTCCGGGGGGATAGTGCTTTTTATACCTGGTTGTATCGTATTGCGGTCAAT
+ACCGCGAAGAACTACCTGGTTGCGCAGGGGCGTCGTCCGCCTTCCAGTGATGTAGACGCG
+ATTGAAGCAGAAAACTTTGAAAGCGGCGGCGCGCTGAAAGAAATTTCGAACCCTGAGAAC
+TTAATGTTGTCAGAAGAACTGAGACAGATAGTTTTCCGAACTATTGAGTCCCTCCCGGAA
+GATTTACGTATGGCAATCACCTTACGGGAGCTGGATGGCCTGAGCTATGAAGAGATAGCG
+GCTATCATGGATTGTCCGGTGGGGACGGTGCGTTCACGTATCTTCCGGGCGCGGGAAGCT
+ATTGATAATAAAGTTCAACCGCTTATCAGGCGTTGA
+>Salmonella_enterica_subsp_enterica_serovar_Typhimurium_str_DT2_v1_02741
+ATGAGCGAGCAGTTAACGGACGTCCTGGTTGAACGGGTCCAGAAGGGAGATCAGAAA
+GCCTTTAACTTACTGGTAGTGCGCTACCAGCATAAAGTGGCGAGTCTGGTTTCCCGCTAT
+GTGCCATCGGGCGACGTTCCCGATGTCGTACAGGAATCATTTATTAAGGCCTATCGCGCG
+CTGGATTCTTTCCGGGGGGATAGTGCTTTTTATACCTGGTTGTATCGTATTGCGGTCAAT
+ACCGCGAAGAACTACCTGGTTGCGCAGGGGCGTCGTCCGCCTTCCAGTGATGTAGACGCG
+ATTGAAGCAGAAAACTTTGAAAGCGGCGGCGCGCTGAAAGAAATTTCGAACCCTGAGAAC
+TTAATGTTGTCAGAAGAACTGAGACAGATAGTTTTCCGAACTATTGAGTCCCTCCCGGAA
+GATTTACGTATGGCAATCACCTTACGGGAGCTGGATGGCCTGAGCTATGAAGAGATAGCG
+GCTATCATGGATTGTCCGGTGGGGACGGTGCGTTCACGTATCTTCCGGGCGCGGGAAGCT
+ATTGATAATAAAGTTCAACCGCTTATCAGGCGTTGA
diff --git a/t/data/mcl_file b/t/data/mcl_file
new file mode 100644
index 0000000..253196c
--- /dev/null
+++ b/t/data/mcl_file
@@ -0,0 +1,5 @@
+6259_8#9_01142 6631_2#11_00851 6631_4#5_01901
+6664_1#21_00211
+6259_8#13_01077
+6630_4#9_00008 6259_5#1_00688 6259_5#8_00815
+6259_7#7_02078 6631_5#24_01032 6593_5#13_00457
\ No newline at end of file
diff --git a/t/data/mdoH.fa.aln b/t/data/mdoH.fa.aln
new file mode 100644
index 0000000..9cbdc63
--- /dev/null
+++ b/t/data/mdoH.fa.aln
@@ -0,0 +1,88 @@
+>11111_1#11_04119
+ATGAATAAAACAACTGAGTATATTGACGCACTGCTGCTTTCTGAACGTGAGAAAGCGGCA
+TTGCCGAAAACTGACATCCGCGCCGTGCATCAGGCGCTGGATGCCGAGCATCGGACTTAC
+TCGCGAGAAGACGATTCACCGCAGGGTTCCGTAAAAGCCCGCCTTGAACACGCCTGGCCG
+GATTCATTGGCGAAGGGGCAGTTAATTAAAGATGATGAAGGGCGCGATCAGTTGCAGGCT
+ATGCCAAAAGCGACGCGCTCTTCGATGTTTCCTGATCCCTGGCGAACCAACCCGGTTGGC
+CGTTTCTGGGATCGCCTGCGTGGGCGGGATGTAACGCCGCGCTATGTTTCTCGTCTGACA
+AAAGAAGAGCAGGCGAGTGAGCAAAAATGGCGTACCGTCGGCACTATACGCCGCTATATT
+TTGTTAATTTTGACTCTGGCGCAAACCGTCGTCGCGACCTGGTATATGAAGACCATTCTG
+CCCTATCAGGGATGGGCGCTCATCAATCCTATGGATATGGTGGGGCAGGATATTTGGGTC
+TCCTTTATGCAGCTCCTGCCCTACATGCTGCAAACCGGTATCCTGATTTTGTTTGCCGTG
+CTGTTCTGCTGGGTGTCTGCCGGATTCTGGACGGCGCTGATGGGCTTCCTGCAACTGCTT
+ATCGGGCGCGATAAGTACAGTATCTCCGCGTCTACGGTTGGCGATGAGCCCCTCAATCCG
+GAACACCAGACGGCGCTGATCATGCCTATCTGTAATGAAGACGTTAGCCGCGTTTTCGCC
+GGTCTGCGCGCGACCTGGGAGTCCGTTAAAGCCACAGGCAACGCCGCGCATTTTGACGTC
+TATATCCTTAGCGATAGTTATAACCCGGATATCTGCGTGGCGGAGCAAAAGGCGTGGATG
+GAGCTCATCGCGGAAGTGCAGGGCGAAGGCCAAATTTTTTACCGTCGCCGCCGCCGCCGT
+ATGAAACGCAAAAGCGGCAATATTGACGATTTTTGCCGCCGCTGGGGCAATCAGTACAGC
+TATATGGTGGTGCTGGACGCGGACTCAGTGATGAGCGGCGAGTGTCTGAGCGGGCTGGTG
+CGCCTGATGGAAGCGAACCCTAACGCCGGGATTATCCAGTCTTCGCCGAAAGCGTCGGGG
+ATGGATACTCTGTATGCCCGCTGCCAACAGTTCGCGACCCGTGTTTATGGACCGCTGTTT
+ACCGCCGGGCTGCACTTCTGGCAGTTGGGGGAGTCGCACTACTGGGGGCACAATGCCATT
+ATCCGCGTGAAGCCGTTTATCGAGCACTGCGCTCTGGCGCCGCTGCCGGGAGAAGGTTCG
+TTCGCCGGATCGATTCTTTCCCACGACTTTGTGGAGGCGGCGCTAATGCGTCGGGCAGGG
+TGGGGCGTCTGGATTGCCTACGATCTCCCCGGCTCCTATGAAGAGCTGCCGCCAAACCTG
+CTGGATGAGCTTAAACGCGACCGCCGCTGGTGTCACGGCAACCTGATGAACTTTCGTCTG
+TTCCTGGTGAAAGGAATGCACCCGGTGCATCGCGCCGTGTTCCTGACCGGGGTAATGTCA
+TACCTGTCCGCGCCGTTATGGTTTATGTTCCTCGCGCTTTCTACCGCGCTGCAGGTCGTT
+CATGCGTTAACAGAGCCGCAATATTTCCTTCAGCCGCGCCAGCTTTTTCCGGTCTGGCCG
+CAGTGGCGTCCGGAACTGGCAATCGCGCTGTTTGCGTCAACGATGGTGCTGCTGTTCCTG
+CCGAAGCTGCTCAGTATTATGCTGATCTGGTGTAAAGGCACCAAAGAGTATGGCGGTTTC
+TGGCGCGTTACGCTGTCGCTATTGCTGGAAGTGCTGTTCTCCGTGTTGCTGGCGCCGGTG
+CGTATGCTGTTTCATACCGTGTTTGTGGTCAGCGCGTTCCTCGGCTGGGAAGTGGTCTGG
+AACTCACCGCAACGCGACGATGATTCTACGCCGTGGGGAGAAGCCTTTATGCGTCACGGC
+TCTCAACTGCTGCTGGGGCTGGTCTGGGCGGTGGGTATGGCGTGGCTGGATTTACGCTTT
+CTGTTCTGGCTGGCGCCGATTGTCTTTTCGCTGATTCTGTCGCCATTTGTTTCGGTGATC
+TCCAGTCGTTCAACGGTAGGATTACGCACCAAACGCTGGAAGCTGTTCCTGATCCCGGAA
+GAGTATTCGCCGCCTCAGGTGTTGGTCGATACCGATAAATATCTGGAGATGAATCGCCGC
+CGTATTCTGGACGATGGCTTTATGCATGCGGTATTTAACCCGTCGCTTAATGCGCTGGCG
+ACCGCGATGGCCACCGCGCGTCACCGCGCCAGTAAGGTGCTGGAAATAGCCCGCGATCGT
+CATGTGGAGCAGGCGCTAAACGAAACGCCGGAGAAACTGAACCGCGATCGGCGTCTGGTT
+TTGCTCAGCGATCCGGTGACGATGGCGCGTTTACACTATCGGGTCTGGAATGCGCCAGAG
+AGATACTCTTCCTGGGTAAACCATTATCAGTCTCTCGTCCTGAATCCGCAGGCGTTGCAG
+GGACGAACATCGTCAGCGGGATAA
+>22222_2#22_04119
+ATGAATAAAACAACTGAGTATATTGACGCACTGCTGCTTTCTGAACGTGAGAAAGCGGCA
+TTGCCGAAAACTGACATCCGCGCCGTGCATCAGGCGCTGGATGCCGAGCATCGGACTTAC
+TCGCGAGAAGACGATTCACCGCAGGGTTCCGTAAAAGCCCGCCTTGAACACGCCTGGCCG
+GATTCATTGGCGAAGGGGCAGTTAATTAAAGATGATGAAGGGCGCGATCAGTTGCAGGCT
+ATGCCAAAAGCGACGCGCTCTTCGATGTTTCCTGATCCCTGGCGAACCAACCCGGTTGGC
+CGTTTCTGGGATCGCCTGCGTGGGCGGGATGTTACGCCGCGCTATGTTTCTCGTCTGACA
+AAAGAAGAGCAGGCGAGTGAGCAAAAATGGCGTACCGTCGGCACTATACGCCGCTATATT
+TTGTTAATTTTGACTCTGGCGCAAACCGTCGTTGCGACCTGGTATATGAAGACCATTCTG
+CCCTATCAGGGATGGGCGCTCATCAATCCTATTGATATGGTGGGGCAGGATATTTGGGTC
+TCCTTTATGCAGCTCCTGCCCTACATGCTGCATACCGGTATCCTGATTTTGTTTGCCGTG
+CTGTTCTGCTGGGTGTCTGCCGGATTCTGGACTGCGCTGATGGGCTTCCTGCAACTGCTT
+ATCGGGCGCGATAAGTACAGTATCTCCGCGTCTACGGTTGGCGATGAGCCCCTCAATCCG
+GAACACCAGACGGCGCTGATCATGCCTATCTGTAATGAAGACGTTAGCCGCGTTTTCGCC
+GGTCTGCGCGCGACCTGGGAGTCCGTTAAAGCTACAGGCAACGCCGCGCATTTTGACGTC
+TATATCCTTAGCGATAGTTATAACCCGGATATTTGCGTGGCGGAGCAAAAGGCGTGGATG
+GAGCTCATCGCGGAAGTGCAGGGCGAAGGCCATATTTTTTACCGTCGCCGCCGCCGCCGT
+ATGAAACGCAAAAGCGGCAATATTGACGATTTTTGCCGCCGCTGGGGCAATCAGTACAGC
+TATATGGTGGTGCTGGACGCGGACTCAGTGATTAGCGGCGAGTGTCTGAGCGGGCTGGTG
+CGCCTGATGGAAGCGAACCCTAACGCCGGGATTATCCAGTCTTCGCCGAAAGCGTCGGGG
+ATGGATACTCTGTATGCCCGCTGCCAACAGTTTGCGACCCGTGTTTATGGACCGCTGTTT
+ACCGCCGGGCTGCACTTCTGGCAGTTGGGGGATTCGCACTACTGGGGGCACAATGCCATT
+ATCCGCGTGAAGCCGTTTATCGAGCACTGCGCTCTGGCGCCGCTGCCGGGAGAAGGTTCG
+TTCGCCGGATCGATTCTTTCCCACGACTTTGTTGAGGCGGCGCTAATGCGTCGGGCAGGG
+TGGGGCGTCTGGATTGCCTACGATCTCCCCGGTTCCTATGAAGAGCTGCCGCCAAACCTG
+CTGGATGAGCTTAAACGCGACCGCCGCTGGTGTCACGGCAACCTGATGAACTTTCGTCTG
+TTCCTGGTGAAAGGAATGCACCCGGTGCATCGTGCCGTGTTCCTGACCGGGGTAATGTCA
+TACCTGTCCGCGCCGTTATGGTTTATGTTCCTTGCGCTTTCTACCGCGCTGCAGGTCGTT
+CATGCGTTAACAGAGCCGCAATATTTCCTTCATCCGCGCCAGCTTTTTCCGGTCTGGCCG
+CAGTGGCGTCCGGAACTGGCAATCGCGCTGTTTGCGTCAACGATGGTGCTGCTGTTCCTG
+CCGAAGCTGCTCAGTATTATGCTGATCTGGTGTAAAGGCACCAAAGAGTATGGCGGTTTC
+TGGCGCGTTACGCTGTCGCTATTGCTGGAAGTTCTGTTCTCCGTGTTGCTGGCGCCGGTG
+CGTATGCTGTTTCATACCGTGTTTGTGGTCAGTGCGTTCCTCGGCTGGGAAGTGGTCTGG
+AACTCACCGCAACGCGACGATGATTCTACGCCTTGGGGAGAAGCCTTTATGCGTCACGGC
+TCTCAACTGCTGCTGGGGCTGGTCTGGGCGGTTGGTATGGCGTGGCTGGATTTACGCTTT
+CTGTTCTGGCTGGCGCCGATTGTCTTTTCGCTTATTCTGTCGCCATTTGTTTCGGTGATC
+TCCAGTCGTTCAACGGTAGGATTACGCACCAATCGCTGGAAGCTGTTCCTGATCCCGGAA
+GAGTATTCGCCGCCTCAGGTGTTGGTCGATACTGATAAATATCTGGAGATGAATCGCCGC
+CGTATTCTGGACGATGGCTTTATGCATGCGGTTTTTAACCCGTCGCTTAATGCGCTGGCG
+ACCGCGATGGCCACCGCGCGTCACCGCGCCAGTAAGGTGCTGGAAATAGCCCGCGATCGT
+CATGTGGAGCAGGCGCTAAACGAAACGCCGGATAAACTGAACCGCGATCGGCGTCTGGTT
+TTGCTCAGCGATCCGGTGACGATGGCGCGTTTTCACTATCGGGTCTGGAATGCGCCAGAG
+AGATACTCTTCCTGGGTAAACCATTATCAGTCTCTCGTCCTGAATCCGCAGGCGTTGCAG
+GGACGAACATCGTCAGCGGGATAA
diff --git a/t/data/mdoH_mafft.fa.aln b/t/data/mdoH_mafft.fa.aln
new file mode 100644
index 0000000..9cbdc63
--- /dev/null
+++ b/t/data/mdoH_mafft.fa.aln
@@ -0,0 +1,88 @@
+>11111_1#11_04119
+ATGAATAAAACAACTGAGTATATTGACGCACTGCTGCTTTCTGAACGTGAGAAAGCGGCA
+TTGCCGAAAACTGACATCCGCGCCGTGCATCAGGCGCTGGATGCCGAGCATCGGACTTAC
+TCGCGAGAAGACGATTCACCGCAGGGTTCCGTAAAAGCCCGCCTTGAACACGCCTGGCCG
+GATTCATTGGCGAAGGGGCAGTTAATTAAAGATGATGAAGGGCGCGATCAGTTGCAGGCT
+ATGCCAAAAGCGACGCGCTCTTCGATGTTTCCTGATCCCTGGCGAACCAACCCGGTTGGC
+CGTTTCTGGGATCGCCTGCGTGGGCGGGATGTAACGCCGCGCTATGTTTCTCGTCTGACA
+AAAGAAGAGCAGGCGAGTGAGCAAAAATGGCGTACCGTCGGCACTATACGCCGCTATATT
+TTGTTAATTTTGACTCTGGCGCAAACCGTCGTCGCGACCTGGTATATGAAGACCATTCTG
+CCCTATCAGGGATGGGCGCTCATCAATCCTATGGATATGGTGGGGCAGGATATTTGGGTC
+TCCTTTATGCAGCTCCTGCCCTACATGCTGCAAACCGGTATCCTGATTTTGTTTGCCGTG
+CTGTTCTGCTGGGTGTCTGCCGGATTCTGGACGGCGCTGATGGGCTTCCTGCAACTGCTT
+ATCGGGCGCGATAAGTACAGTATCTCCGCGTCTACGGTTGGCGATGAGCCCCTCAATCCG
+GAACACCAGACGGCGCTGATCATGCCTATCTGTAATGAAGACGTTAGCCGCGTTTTCGCC
+GGTCTGCGCGCGACCTGGGAGTCCGTTAAAGCCACAGGCAACGCCGCGCATTTTGACGTC
+TATATCCTTAGCGATAGTTATAACCCGGATATCTGCGTGGCGGAGCAAAAGGCGTGGATG
+GAGCTCATCGCGGAAGTGCAGGGCGAAGGCCAAATTTTTTACCGTCGCCGCCGCCGCCGT
+ATGAAACGCAAAAGCGGCAATATTGACGATTTTTGCCGCCGCTGGGGCAATCAGTACAGC
+TATATGGTGGTGCTGGACGCGGACTCAGTGATGAGCGGCGAGTGTCTGAGCGGGCTGGTG
+CGCCTGATGGAAGCGAACCCTAACGCCGGGATTATCCAGTCTTCGCCGAAAGCGTCGGGG
+ATGGATACTCTGTATGCCCGCTGCCAACAGTTCGCGACCCGTGTTTATGGACCGCTGTTT
+ACCGCCGGGCTGCACTTCTGGCAGTTGGGGGAGTCGCACTACTGGGGGCACAATGCCATT
+ATCCGCGTGAAGCCGTTTATCGAGCACTGCGCTCTGGCGCCGCTGCCGGGAGAAGGTTCG
+TTCGCCGGATCGATTCTTTCCCACGACTTTGTGGAGGCGGCGCTAATGCGTCGGGCAGGG
+TGGGGCGTCTGGATTGCCTACGATCTCCCCGGCTCCTATGAAGAGCTGCCGCCAAACCTG
+CTGGATGAGCTTAAACGCGACCGCCGCTGGTGTCACGGCAACCTGATGAACTTTCGTCTG
+TTCCTGGTGAAAGGAATGCACCCGGTGCATCGCGCCGTGTTCCTGACCGGGGTAATGTCA
+TACCTGTCCGCGCCGTTATGGTTTATGTTCCTCGCGCTTTCTACCGCGCTGCAGGTCGTT
+CATGCGTTAACAGAGCCGCAATATTTCCTTCAGCCGCGCCAGCTTTTTCCGGTCTGGCCG
+CAGTGGCGTCCGGAACTGGCAATCGCGCTGTTTGCGTCAACGATGGTGCTGCTGTTCCTG
+CCGAAGCTGCTCAGTATTATGCTGATCTGGTGTAAAGGCACCAAAGAGTATGGCGGTTTC
+TGGCGCGTTACGCTGTCGCTATTGCTGGAAGTGCTGTTCTCCGTGTTGCTGGCGCCGGTG
+CGTATGCTGTTTCATACCGTGTTTGTGGTCAGCGCGTTCCTCGGCTGGGAAGTGGTCTGG
+AACTCACCGCAACGCGACGATGATTCTACGCCGTGGGGAGAAGCCTTTATGCGTCACGGC
+TCTCAACTGCTGCTGGGGCTGGTCTGGGCGGTGGGTATGGCGTGGCTGGATTTACGCTTT
+CTGTTCTGGCTGGCGCCGATTGTCTTTTCGCTGATTCTGTCGCCATTTGTTTCGGTGATC
+TCCAGTCGTTCAACGGTAGGATTACGCACCAAACGCTGGAAGCTGTTCCTGATCCCGGAA
+GAGTATTCGCCGCCTCAGGTGTTGGTCGATACCGATAAATATCTGGAGATGAATCGCCGC
+CGTATTCTGGACGATGGCTTTATGCATGCGGTATTTAACCCGTCGCTTAATGCGCTGGCG
+ACCGCGATGGCCACCGCGCGTCACCGCGCCAGTAAGGTGCTGGAAATAGCCCGCGATCGT
+CATGTGGAGCAGGCGCTAAACGAAACGCCGGAGAAACTGAACCGCGATCGGCGTCTGGTT
+TTGCTCAGCGATCCGGTGACGATGGCGCGTTTACACTATCGGGTCTGGAATGCGCCAGAG
+AGATACTCTTCCTGGGTAAACCATTATCAGTCTCTCGTCCTGAATCCGCAGGCGTTGCAG
+GGACGAACATCGTCAGCGGGATAA
+>22222_2#22_04119
+ATGAATAAAACAACTGAGTATATTGACGCACTGCTGCTTTCTGAACGTGAGAAAGCGGCA
+TTGCCGAAAACTGACATCCGCGCCGTGCATCAGGCGCTGGATGCCGAGCATCGGACTTAC
+TCGCGAGAAGACGATTCACCGCAGGGTTCCGTAAAAGCCCGCCTTGAACACGCCTGGCCG
+GATTCATTGGCGAAGGGGCAGTTAATTAAAGATGATGAAGGGCGCGATCAGTTGCAGGCT
+ATGCCAAAAGCGACGCGCTCTTCGATGTTTCCTGATCCCTGGCGAACCAACCCGGTTGGC
+CGTTTCTGGGATCGCCTGCGTGGGCGGGATGTTACGCCGCGCTATGTTTCTCGTCTGACA
+AAAGAAGAGCAGGCGAGTGAGCAAAAATGGCGTACCGTCGGCACTATACGCCGCTATATT
+TTGTTAATTTTGACTCTGGCGCAAACCGTCGTTGCGACCTGGTATATGAAGACCATTCTG
+CCCTATCAGGGATGGGCGCTCATCAATCCTATTGATATGGTGGGGCAGGATATTTGGGTC
+TCCTTTATGCAGCTCCTGCCCTACATGCTGCATACCGGTATCCTGATTTTGTTTGCCGTG
+CTGTTCTGCTGGGTGTCTGCCGGATTCTGGACTGCGCTGATGGGCTTCCTGCAACTGCTT
+ATCGGGCGCGATAAGTACAGTATCTCCGCGTCTACGGTTGGCGATGAGCCCCTCAATCCG
+GAACACCAGACGGCGCTGATCATGCCTATCTGTAATGAAGACGTTAGCCGCGTTTTCGCC
+GGTCTGCGCGCGACCTGGGAGTCCGTTAAAGCTACAGGCAACGCCGCGCATTTTGACGTC
+TATATCCTTAGCGATAGTTATAACCCGGATATTTGCGTGGCGGAGCAAAAGGCGTGGATG
+GAGCTCATCGCGGAAGTGCAGGGCGAAGGCCATATTTTTTACCGTCGCCGCCGCCGCCGT
+ATGAAACGCAAAAGCGGCAATATTGACGATTTTTGCCGCCGCTGGGGCAATCAGTACAGC
+TATATGGTGGTGCTGGACGCGGACTCAGTGATTAGCGGCGAGTGTCTGAGCGGGCTGGTG
+CGCCTGATGGAAGCGAACCCTAACGCCGGGATTATCCAGTCTTCGCCGAAAGCGTCGGGG
+ATGGATACTCTGTATGCCCGCTGCCAACAGTTTGCGACCCGTGTTTATGGACCGCTGTTT
+ACCGCCGGGCTGCACTTCTGGCAGTTGGGGGATTCGCACTACTGGGGGCACAATGCCATT
+ATCCGCGTGAAGCCGTTTATCGAGCACTGCGCTCTGGCGCCGCTGCCGGGAGAAGGTTCG
+TTCGCCGGATCGATTCTTTCCCACGACTTTGTTGAGGCGGCGCTAATGCGTCGGGCAGGG
+TGGGGCGTCTGGATTGCCTACGATCTCCCCGGTTCCTATGAAGAGCTGCCGCCAAACCTG
+CTGGATGAGCTTAAACGCGACCGCCGCTGGTGTCACGGCAACCTGATGAACTTTCGTCTG
+TTCCTGGTGAAAGGAATGCACCCGGTGCATCGTGCCGTGTTCCTGACCGGGGTAATGTCA
+TACCTGTCCGCGCCGTTATGGTTTATGTTCCTTGCGCTTTCTACCGCGCTGCAGGTCGTT
+CATGCGTTAACAGAGCCGCAATATTTCCTTCATCCGCGCCAGCTTTTTCCGGTCTGGCCG
+CAGTGGCGTCCGGAACTGGCAATCGCGCTGTTTGCGTCAACGATGGTGCTGCTGTTCCTG
+CCGAAGCTGCTCAGTATTATGCTGATCTGGTGTAAAGGCACCAAAGAGTATGGCGGTTTC
+TGGCGCGTTACGCTGTCGCTATTGCTGGAAGTTCTGTTCTCCGTGTTGCTGGCGCCGGTG
+CGTATGCTGTTTCATACCGTGTTTGTGGTCAGTGCGTTCCTCGGCTGGGAAGTGGTCTGG
+AACTCACCGCAACGCGACGATGATTCTACGCCTTGGGGAGAAGCCTTTATGCGTCACGGC
+TCTCAACTGCTGCTGGGGCTGGTCTGGGCGGTTGGTATGGCGTGGCTGGATTTACGCTTT
+CTGTTCTGGCTGGCGCCGATTGTCTTTTCGCTTATTCTGTCGCCATTTGTTTCGGTGATC
+TCCAGTCGTTCAACGGTAGGATTACGCACCAATCGCTGGAAGCTGTTCCTGATCCCGGAA
+GAGTATTCGCCGCCTCAGGTGTTGGTCGATACTGATAAATATCTGGAGATGAATCGCCGC
+CGTATTCTGGACGATGGCTTTATGCATGCGGTTTTTAACCCGTCGCTTAATGCGCTGGCG
+ACCGCGATGGCCACCGCGCGTCACCGCGCCAGTAAGGTGCTGGAAATAGCCCGCGATCGT
+CATGTGGAGCAGGCGCTAAACGAAACGCCGGATAAACTGAACCGCGATCGGCGTCTGGTT
+TTGCTCAGCGATCCGGTGACGATGGCGCGTTTTCACTATCGGGTCTGGAATGCGCCAGAG
+AGATACTCTTCCTGGGTAAACCATTATCAGTCTCTCGTCCTGAATCCGCAGGCGTTGCAG
+GGACGAACATCGTCAGCGGGATAA
diff --git a/t/data/multfasta1.aln b/t/data/multfasta1.aln
new file mode 100644
index 0000000..a72cb20
--- /dev/null
+++ b/t/data/multfasta1.aln
@@ -0,0 +1,8 @@
+>1111_1#1_00123
+AAAAA-
+>2222_2#2_00456
+CCCCC-
+>3333_3#3_00789
+TTTTT-
+>4444_4#4_00123
+GGGGG-
diff --git a/t/data/multfasta2.aln b/t/data/multfasta2.aln
new file mode 100644
index 0000000..db31669
--- /dev/null
+++ b/t/data/multfasta2.aln
@@ -0,0 +1,8 @@
+>1111_1#1_01123
+CCCC----
+>2222_2#2_01456
+AAAA----
+>3333_3#3_01789
+GGGG----
+>4444_4#4_01123
+TTTT----
diff --git a/t/data/multfasta3.aln b/t/data/multfasta3.aln
new file mode 100644
index 0000000..376ac47
--- /dev/null
+++ b/t/data/multfasta3.aln
@@ -0,0 +1,8 @@
+>1111_1#1_02123
+TTTTTTTTTTTTTTT
+>2222_2#2_02456
+AAAAAAAAAAAAAAA
+>3333_3#3_02789
+CCCCCCCCCCCCCCC
+>4444_4#4_02123
+GGGGGGGGGGGGGGG
diff --git a/t/data/multfasta4.aln b/t/data/multfasta4.aln
new file mode 100644
index 0000000..4946e2d
--- /dev/null
+++ b/t/data/multfasta4.aln
@@ -0,0 +1,7 @@
+>1111_1#1_0001
+-AAAA-
+>2222_2#2_0001
+-TTTT-
+>4444_4#4_0001
+-CCCC-
+
diff --git a/t/data/multfasta5.aln b/t/data/multfasta5.aln
new file mode 100644
index 0000000..650ca13
--- /dev/null
+++ b/t/data/multfasta5.aln
@@ -0,0 +1,7 @@
+>1111_1#1_0004
+-AAAA-
+>2222_2#2_0004
+-TTTT-
+>4444_4#4_0004
+-CCCC-
+
diff --git a/t/data/multifasta_files/expected_output.embl b/t/data/multifasta_files/expected_output.embl
new file mode 100644
index 0000000..32519f0
--- /dev/null
+++ b/t/data/multifasta_files/expected_output.embl
@@ -0,0 +1,19 @@
+ID Genome standard; DNA; PRO; 1234 BP.
+XX
+FH Key Location/Qualifiers
+FH
+FT feature 1..1
+FT /label=1
+FT /locus_tag=1
+FT feature 2..11
+FT /label=outof_order
+FT /locus_tag=outof_order
+FT feature 12..111
+FT /label=2
+FT /locus_tag=2
+FT feature 112..1111
+FT /label=3
+FT /locus_tag=3
+XX
+SQ Sequence 1234 BP; 789 A; 1717 C; 1693 G; 691 T; 0 other;
+//
diff --git a/t/data/nnn_at_end.fa b/t/data/nnn_at_end.fa
new file mode 100644
index 0000000..d13361d
--- /dev/null
+++ b/t/data/nnn_at_end.fa
@@ -0,0 +1,8 @@
+>1
+AAANNN
+>2
+AAACCCnNn
+>3
+AAACCCGGGnnn
+>4
+AAACCCGGGTTTNNN
\ No newline at end of file
diff --git a/t/data/nnn_at_end.fa.sorted.fa b/t/data/nnn_at_end.fa.sorted.fa
new file mode 100644
index 0000000..87b65fc
--- /dev/null
+++ b/t/data/nnn_at_end.fa.sorted.fa
@@ -0,0 +1,8 @@
+>1
+AAA
+>2
+AAACCC
+>3
+AAACCCGGG
+>4
+AAACCCGGGTTT
diff --git a/t/data/nuc_multifasta.fa b/t/data/nuc_multifasta.fa
new file mode 100644
index 0000000..d5bc8c5
--- /dev/null
+++ b/t/data/nuc_multifasta.fa
@@ -0,0 +1,112 @@
+>AAAA#74_01075
+TGTCAGTACCACTTATTCTGACCTTACTGGCGGGCGCTGCCACCTTTATTGGCGCGTTTC
+TTGGCGTTCTTGGCCAAAAACCGTCTAACCGCGTGCTGGCTTTTTCGCTGGGCTTCGCCG
+CAGGGATCATGCTGCTCATCTCGCTGATGGAGATGCTGCCCGCCGCGTTAGATACCGAGG
+GGATGTCGCCTGTACTGGGCTACGGGATGTTTATTATCGGCCTGTTGGGCTACTTCGGGC
+TGGATCGTCTGCTTCCTCACGCTCATCCGCAGGATCTGGTGCAAAAAAGGCAGCAGCCGC
+TTCCCGGCTCGATAAAACGCACTGCGATTTTATTGACGCTCGGCATTAGCCTGCACAACT
+TTCCGGAAGGAATCGCCACCTTTGTCACTGCCAGCAGCAATCTTGAACTGGGTTTCGGCA
+TCGCACTGGCGGTGGCGTTGCACAATATTCCTGAAGGGCTGGCGGTTGCCGGCCCGGTTT
+ATGCCGCGACGGGCTCAAAACGTACCGCGATTTTTTGGGCCGGTATCTCCGGCATGGCGG
+AAATTCTTGGCGGCGTGCTGGCGTGGCTGATTTTGGGCAGCCTGGTTTCACCGATCGTTA
+TGGCGGCTATCATGGCAGCAGTCGCCGGCATTATGGTGGCGCTCTCCGTCGATGAACTGA
+TGCCGTTGGCAAAAGAGATCGATCCTAACAATAACCCCAGCTATGGTGTGCTTTGCGGTA
+TGTCCATCATGGGGCTCAGTCTCGTCATTTTGCAGACGATAGGTATCGGTTAA
+>BBBB#75_01314
+ATGTCAGTACCACTTATTCTGACCTTACTGGCGGGCGCTGCCACCTTTATTGGCGCGTTT
+CTTGGCGTTCTTGGCCAAAAACCGTCTAACCGCGTGCTGGCTTTTTCGCTGGGCTTCGCC
+GCAGGGATCATGCTGCTCATCTCGCTGATGGATGCTGCCCGCCGCGTTAGATACCGAGGG
+GATGTCGCCTGTACTGGGCTACGGGATGTTTATTATCGGCCTGTTGGGCTACTTCGGGCT
+GGATCGTCTGCTTCCTCACGCTCATCCGCAGGATCTGGTGCAAAAAAGGCAGCAGCCGCT
+TCCCGGCTCGATAAAACGCACTGCGATTTTATTGACGCTCGGCATTAGCCTGCACAACTT
+TCCGGAAGGAATCGCCACCTTTGTCACTGCCAGCAGCAATCTTGAACTGGGTTTCGGCAT
+CGCACTGGCGGTGGCGTTGCACAATATTCCTGAAGGGCTGGCGGTTGCCGGCCCGGTTTA
+TGCCGCGACGGGCTCAAAACGTACCGCGATTTTTTGGGCCGGTATCTCCGGCATGGCGGA
+AATTCTTGGCGGCGTGCTGGCGTGGCTGATTTTGGGCAGCCTGGTTTCACCGATCGTTAT
+GGCGGCTATCATGGCAGCAGTCGCCGGCATTATGGTGGCGCTCTCCGTCGATGAACTGAT
+GCCGTTGGCAAAAGAGATCGATCCTAACAATAACCCCAGCTATGGTGTGCTTTGCGGTAT
+GTCCATCATGGGGCTCAGTCTCGTCATTTTGCAGACGATAGGTATCGGTTAA
+>CCCC#76_00877
+ATGTCAGTACCACTTATTCTGACCTTACTGGCGGGCGCTGCCACCTTTATTGGCGCGTTT
+CTTGGCGTTCTTGGCCAAAAACCGTCTAACCGCGTGCTGGCTTTTTCGCTGGGCTTCGCC
+GCAGGGATCATGCTGCTCATCTCGCTGATGGAGATGCTGCCCGCCGCGTTAGATACCGAG
+GGGATGTCGCCTGTACTGGGCTACGGGAGTTTATTATCGGCCTGTTGGGCTACTTCGGGC
+TGGATCGTCTGCTTCCTCACGCTCATCCGCAGGATCTGGTGCAAAAAAGGCAGCAGCCGC
+TTCCCGGCTCGATAAAACGCACTGCGATTTTATTGACGCTCGGCATTAGCCTGCACAACT
+TTCCGGAAGGAATCACCTTTGTCACTGCCAGCAGCAATCTTGAACTGGGTTTCGGCATCG
+CACTGGCGGTGGCGTTGCACAATATTCCTGAAGGGCTGGCGGTTGCCGGCCCGGTTTATG
+CCGCGACGGGCTCAAAACGTACCGCGATTTTTTGGGCCGGTATCTCCGGCATGGCGGAAA
+TTCTTGGCGGCGTGCTGGCGTGGCTGATTTTGGGCAGCCTGGTTTCACCGATCGTTATGG
+CGGCTATCATGGCAGCAGTCGCCGGCATTATGGTGGCGCTCTCCGTCGATGAACTGATGC
+CGTTGGCAAAAGAGATCGATCCTAACAATAACCCCAGCTATGGTGTGCTTTGCGGTATGT
+CCATCATGGGGCTCAGTCTCGTCATTTTGCAGACGATAGGTATCGGTTAA
+>DDDD#77_01105
+ATGTCAGTACCACTTATTCTGACCTTACTGGCGGGCGCTGCCACCTTTATTGGCGCGTTT
+CTTGGCGTTCTTGGCCAAAAACCGTCTAACCGCGTGCTGGCTTTTTCGCTGGGCTTCGCC
+GCAGGGATCATGCTGCTCATCTCGCTGATGGAGATGCTGCCCGCCGCGTTAGATACCGAG
+GGGATGTCGCCTGTACTGGGCTACGGGATGTTTATTATCGGCCTGTTGGGCTACTTCGGG
+CTGGATCGTCTGCTTCCTCACGCTCATCCGCAGGATCTGGTGCAAAAAAGGCAGCAGCCG
+CTTCCCGGCTCGATAAAACGCACTGCGATTTTATTGACGCTCGGCATTAGCCTGCACAAC
+TTTCCGGAAGGAATCGCCACCTTTGTCACTGCCAGCAGCAATCTTGAACTGGGTTTCGGC
+ATCGCACTGGCGGTGGCGTTGCACAATATTCCTGAAGGGCTGGCGGTTGCCGGCCCGGTT
+TATGCCGCGACGGGCTCAAAACGTACCGCGATTTTTTGGGCCGGTATCTCCGGCATGGCG
+GAAATTCTTGGCGGCGTGCTGGCGTGGCTGATTTTGGGCAGCCTGGTTTCACCGATCGTT
+ATGGCGGCTATCATGGCAGCAGTCGCCGGCATTATGGTGGCGCTCTCCGTCGATGAACTG
+ATGCCGTTGGCAAAAGAGATCGATCCTAACAATAACCCCAGCTATGGTGTGCTTTGCGGT
+ATGTCCATCATGGGGCTCAGTCTCGTCATTTTGCAGACGATAGGTATCGGTTAA
+>EEEE
+ATGTCAGTACCACTTATTCTGACCTTACTGGCGGGCGCTGCCACCTTTATTGGCGCGTTT
+CTTGGCGTTCTTGGCCAAAAACCGTCTAACCGCGTGCTGGCTTTTTCGCTGGGCTTCGCC
+GCAGGGATCATGCTGCTCATCTCGCTGATGGAGATGCTGCCCGCCGCGTTAGATACCGAG
+GGGATGTCGCCTGTACTGGGCTACGGGATGTTTATTATCGGCCTGTTGGGCTACTTCGGG
+CTGGATCGTCTGCTTCCTCACGCTCATCCGCAGGATCTGGTGCAAAAAAGGCAGCAGCCG
+CTTCCCGGCTCGATAAAACGCACTGCGATTTTATTGACGCTCGGCATTAGCCTGCACAAC
+TTTCCGGAAGGAATCGCCACCTTTGTCACTGCCAGCAGCAATCTTGAACTGGGTTTCGGC
+ATCGCACTGGCGGTGGCGTTGCACAATATTCCTGAAGGGCTGGCGGTTGCCGGCCCGGTT
+TATGCCGCGACGGGCTCAAAACGTACCGCGATTTTTTGGGCCGGTATCTCCGGCATGGCG
+GAAATTCTCGGCGTGCTGGCGTGGCTGATTTTGGGCAGCCTGGTTTCACCGATCGTTATG
+GCGGCTATCATGGCAGCAGTCGCCGGCATTATGGTGGCGCTCTCCGTCGATGAACTGATG
+CCGTTGGCAAAAGAGATCGATCCTAACAATAACCCCAGCTATGGTGTGCTTTGCGGTATG
+TCCATCATGGGGCTCAGTCTCGTCATTTTGCAGACGATAGGTATCGGTTAA
+>FFFF
+ATGTCAGTACCACTTATTCTGACCTTACTGGCGGGCGCTGCCACCTTTATTGGCGCGTTT
+CTTGGCGTTCTTGGCCAAAAACCGTCTAACCGCGTGCTGGCTTTTTCGCTGGGCTTCGCC
+GCAGGGATCATGCTGCTCATCTCGCTGATGGAGATGCTGCCCGCCGCGTTAGATACCGAG
+GGGATGTCGCCTGTACTGGGCTACGGGATGTTTATTATCGGCCTGTTGGGCTACTTCGGG
+CTGGATCGTCTGCTTCCTCACGCTCATCCGCAGGATCTGGTGCAAAAAAGGCAGCAGCCG
+CTTCCCGGCTCGATAAAACGCACTGCGATTTTATTGACGCTCGGCATTAGCCTGCACAAC
+TTTCCGGAAGGAATCGCCACCTTTGTCACTGCCAGCAGCAATCTTGAACTGGGTTTCGGC
+ATCGCACTGGCGGTGGCGTTGCACAATATTCCTGAAGGGCTGGCGGTTGCCGGCCCGGTT
+TATGCCGCGACGGGCTCAAAACGTACCGCGATTTTTTGGGCCGGTATCTCCGGCATGGCG
+GAAATTCTTGGCGGCGTGCTGGCGTGGCTGATTTTGGGCAGCCTGGCACCGATCGTTATG
+GCGGCTATCATGGCAGCAGTCGCCGGCATTATGGTGGCGCTCTCCGTCGATGAACTGATG
+CCGTTGGCAAAAGAGATCGATCCTAACAATAACCCCAGCTATGGTGTGCTTTGCGGTATG
+TCCATCATGGGGCTCAGTCTCGTCATTTTGCAGACGATAGGTATCGGTTAA
+>GGGG
+ATGTCAGTACCACTTATTCTGACCTTACTGGCGGGCGCTGCCACCTTTATTGGCGCGTTT
+CTTGGCGTTCTTGGCCAAAAACCGTCTAACCGCGTGCTGGCTTTTTCGCTGGGCTTCGCC
+GCAGGGATCATGCTGCTCATCTCGCTGATGGAGATGCTGCCCGCCGCGTTAGATACCGAG
+GGGATGTCGCCTGTACTGGGCTACGGGATGTTTATTATCGGCCTGTTGGGCTACTTCGGG
+CTGGATCGTCTGCTTCCTCACGCTCATCCGCAGGATCTGGTGCAAAAAAGGCAGCAGCCG
+CTTCCCGGCTCGATAAAACGCACTGCGATTTTATTGACGCTCGGCATTAGCCTGCACAAC
+TTTCCGGAAGGAATCGCCACCTTTGTCACTGCCAGCAGCAATCTTGAACTGGGTTTCGGC
+ATCGCACTGGGGTGGCGTTGCACAATATTCCTGAAGGGCTGGCGGTTGCCGGCCCGGTTT
+ATGCCGCGACGGGCTCAAAACGTACCGCGATTTTTTGGGCCGGTATCTCCGGCATGGCGG
+AAATTCTTGGCGGCGTGCTGGCGTGGCTGATTTTGGGCAGCCTGGTTTCACCGATCGTTA
+TGGCGGCTATCATGGCAGCAGTCGCCGGCATTATGGTGGCGCTCTCCGATGAACTGATGC
+CGTTGGCAAAAGAGATCGATCCTAACAATAACCCCAGCTATGGTGTGCTTTGCGGTATGT
+CCATCATGGGGCTCAGTCTCGTCATTTTGCAGACGATAGGTATCGGTTAA
+>HHHH
+ATGTCAGTACCACTTATTCTGACCTTACTGGCGGGCGCTGCCACCTTTATTGGCGCGTTT
+CTTGGCGTTCTTGGCCAAAAACCGTCTAACCGCGTGCTGGCTTTTTCGCTGGGCTTCGCC
+GCAGGGATCATGCTGCTCATCTCGCTGATGGAGATGCTGCCCGCCGCGTTAGATACCGAG
+GGGATGTCGCCTGTACTGGGCTACGGGATGTTTATTATCGGCCTGTTGGGCTACTTCGGG
+CTGGATCGTCTGCTTCCTCACGCTTCCGCAGGATCTGGTGCAAAAAAGGCAGCAGCCGCT
+TCCCGGCTCGATAAAACGCACTGCGATTTTATTGACGCTCGGCATTAGCCTGCACAACTT
+TCCGGAAGGAATCGCCACCTTTGTCACTGCCAGCAGCAATCTTGAACTGGGTTTCGGCAT
+CGCACTGGCGGTGGCGTTGCACAATATTCCTGAAGGGCTGGCGGTTGCCGGCCCGGTTTA
+TGCCGCGACGGGCTCAAAACGTACCGCGATTTTTTGGGCCGGTATCTCCGGCATGGCGGA
+AATTCTTGGCGGCGTGCTGGCGTGGCTGATTTTGGGCAGCCTGGTTTCACCGATCGTTAT
+GGCGGCTATCATGGCAGCAGTCGCCGGCATTATGGTGGCGCTCTCCGTCGATGAACTGAT
+GCCGTTGGCAAAAGAGATCGATCCTAACAATAACCCCAGCTATGGTGTGCTTTGCGGTAT
+GTCCATCATGGGGCTCAGTCTCGTCATTTTGCAGACGATAGGTATCGGTTAA
diff --git a/t/data/nuc_to_be_aligned.fa b/t/data/nuc_to_be_aligned.fa
new file mode 100644
index 0000000..a7e81a1
--- /dev/null
+++ b/t/data/nuc_to_be_aligned.fa
@@ -0,0 +1,90 @@
+>1
+ATGCAAATACAGAGCTTCTATCACTCAGCTTCACTAAAAACCCAGGAGGCTTTTAAAAGC
+CTACAAAAAACCTTATACAACGGAATGCAGATTCTCTCAGGCCAGGGCAAAGCGCCGGCT
+AAAGCGCCCGACGCTCGCCCGGAAATTATTGTCCTGCGAGAACCTGGCGCGACATGGGGG
+AATTATCTACAGCATCAGAAGACGTCTAACCACTCGCTGCATAACCTCTATAACTTACAG
+CGCGATCTTCTTACCGTCGCGGCAACCGTTCTGGGTAAACAAGACCCGGTTCTAACGTCA
+ATGGCAAACCAAATGGAGTTAGCCAAAGTTAAAGCGGACCGGCCAGCAACAAAACAAGAA
+GAAGCTGCGGCAAAAGCATTGAAGAAAAATCTTATCGAACTTATTGCAGCACGCACTCAG
+CAGCAAAATGGCTTACCTGCAAAAGAAGCTCATCGCTTTGCGGCAGTAGCGTTTAGAGAT
+GCTCAGGTCAAGCAGCTCAATAACCAGCCCTGGCAAACCATAAAAAATACACTCACGCAT
+AACGGGCATCACTATACCAACACGCAGCTCCCTGCCGCAGAGATGAAAATCGGCGCAAAA
+GATATCTTTCCCAGTGCTTATGAGGGAAAGGGCGTATGCAGTTGGGATACCAAGAATATT
+CATCACGCCAATAATTTGTGGATGTCCACGGTGAGTGTGCATGAGGACGGTAAAGATAAA
+ACGCTTTTTTGCGGGATACGTCATGGTGTGCTTTCCCCCTATCATGAAAAAGATCCGCTT
+CTGCGTCAGGCCGGCGCTGAAAACAAAGCCAAAGAAGTATTAGCTGCGGCACTTTTTAGT
+AAACCTGAGTTGCTTAACAGAGCCTTAGAGGGCGAAGCGGTAAGCCTGAAACTGGTATCC
+GTCGGGTTACTCACCGCGTCGAATATTTTCGGCAAAGAGGGAACTATGGTCGAGGATCAA
+ATGCGCGCATGGCAATCGTTGACCCAGCCGGGAAAAATGATTCATTTAAAAATCCGCAAT
+AAAGATGGCGATCTACAGACGGTAAAAATAAAACCGGACGTCGCCGCATTTAATGTGGGT
+GTTAATGAGCTGGCGCTCAAGCTCGGCTTTGGCCTTAAAGCATCAGATAGCTATAATGCC
+GAAGCGCTGCATCAGTTATTAGGCAATGATTTACGCCCTGAAGCCAGACCAGGTGGCTGG
+GTTGGCGAATGGCTGGCGCAATACCCGGATAATTATGAGGTCGTCAATACATTAGCGCGC
+CAGATTAAGGATATCTGGAAAAATAACCAACATCATAAAGATGGCGGCGAACCCTATAAA
+CTCGCACAACGCCTTGCCATGTTAGCCCATGAAATTGACGCGGTGCCCGCCTGGAATTGT
+AAAAGCGGCAAAGATCGTACAGGGATGATGGATTCAGAAATCAAGCGAGAGCTCATTTCT
+TTCCATCAGACCCATATGTTAAGTGCGCCTGGTAGTCTTCCGGATAGCGGTGGACAGAAA
+ATTTTCCAAAAAGTATTACTGAATAGCGGTAACCTGGAGATTCAGAAACAAAATACGGGC
+GGGGCGGGAAACAAAGTAATGAAAAATTTATCGCCAGAGGTGCTCAATCTTTCCTATCAA
+AAACGAGTTGGGGATGAAAATATTTGGCGTCAGTAAAATATTTCTTCATTAATCACA
+TCT
+>2
+ATGCAAATACAGAGCTTCTATCACTCAGCTTCACTAAAAACCCAGGAGGCTTTTAAAAGC
+CTACAAAAAACCTTATACAACGGAATGCAGATTCTCTCAGGCCAGGGCAAAGCGCCGGCT
+AAAGCGCCCGACGCTCGCCCGGAAATTATTGTCCTGCGAGAACCTGGCGCGACATGGGGG
+AATTATCTACAGCATCAGAAGACGTCTAACCACTCGCTGCATAACCTCTATAACTTACAG
+CGCGATCTTCTTACCGTCGCGGCAACCGTTCTGGGTAAACAAGACCCGGTTCTAACGTCA
+ATGGCAAACCAAATGGAGTTAGCCAAAGTTAAAGCGGACCGGCCAGCAACAAAACAAGAA
+GAAGCTGCGGCAAAAGCATTGAAGAAAAATCTTATCGAACTTATTGCAGCACGCACTCAG
+CAGCAAAATGGCTTACCTGCAAAAGAAGCTCATCGCTTTGCGGCAGTAGCGTTTAGAGAT
+GCTCAGGTCAAGCAGCTCAATAACCAGCCCTGGCAAACCATAAAAAATACACTCACGCAT
+AACGGGCATCACTATACCAACACGCAGCTCCCTGCAGAGATGAAAATCGGCGCAAAA
+GATATCTTTCCCAGTGCTTATGAGGGAAAGGGCGTATGCAGTTGGGATACCAAGAATATT
+CATCACGCCAATAATTTGTGGGTGTCCACGGTGAGTGTGCATGAGGACGGTAAAGATAAA
+ACGCTTTTTTGCGGGATACGTCATGGTGTGCTTTCCCCCTATCATGAAAAAGATCCGCTT
+CTGCGTCAGGCCGGCGCTGAAAACAAAGCCAAAGAAGTATTAGCTGCGGCACTTTTTAGT
+AAACCTGAGTTGCTTAACAGAGCCTTAGAGGGCGAAGCGGTAAGCCTGAAACTGGTATCC
+GTCGGGTTACTCACCGCGTCGAATATTTTCGGCAAAGAGGGAACTATGGTCGAGGATCAA
+ATGCGCGCATGGCAATCGTTGACCCAGCCGGGAAAAATGATTCATTTAAAAATCCGCAAT
+AAAGATGGCGATCTACAGACGGTAAAAATAAAACCGGACGTCGCCGCATTTAATGTGGGT
+GTTAATGAGCTGGCGCTCAAGCTCGGCTTTGGCCTTAAAGCATCAGATAGCTATAATGCC
+GAAGCGCTACATCAGTTATTAGGCAATGATTTACGCCCTGAAGCCAGACCAGGTGGCTGG
+GTTGGCGAATGGCTGGCGCAATACCCGGATAATTATGAGGTCGTCAATACATTAGCGCGC
+CAGATTAAGGATATCTGGAAAAATAACCAACATCATAAAGATGGCGGCGAACCCTATAAA
+CTCGCACAACGCCTTGCCATGTTAGCCCATGAAATTGACGCGGTGCCCGCCTGGAATTGT
+AAAAGCGGCAAAGATCGTACAGGGATGATGGATTCAGAAATCAAGCGAGAGCTCATTTCT
+TTCCATCAGACCCATATGTTAAGTGCGCCTGGTAGTCTTCCGGATAGCGGTGGACAGAAA
+ATTTTCCAAAAAGTATTACTGAATAGCGGTAACCTGGAGATTCAGAAACAAAATACGGGC
+GGGGCGGGAAACAAAGTAATGAAAAATTTATCGCCAGAGGTGCTCAATCTTTCCTATCAA
+AAACGAGTTGGGGATGAAAATATTTGGCAGTCAGTAAAAGGTATTTCTTCATTAATCACA
+TCT
+>3
+ATGCAAATACAGAGCTTCTATCACTCAGCTTCACTAAAAACCCAGGAGGCTTTTAAAAGC
+CTACAAAAAACCTTATACAACGGAATGCAGATTCTCTCAGGCCAGGGCAAAGCGCCGGCT
+AAAGCGCCCGACGCTCGCCCGGAAATTATTGTCCTGCGAGAACCTGGCGCGACATGGGGG
+AATTATCTACAGCATCAGAAGACGTCTAACCACTCGCTGCATAACCTCTATAACTTACAG
+CGCGATCTTCTTACCGTCGCGGCAACCGTTCTGGGTAAACAAGACCCGGTTCTAACGTCA
+ATGGCAAACCAAATGGAGTTAGCCAAGGTTAAAGCGGACCGGCCAGCAACAAAACAAGAA
+GAAGCTGCGGCAAAAGCATTGAAGAAAAATCTTATCGAACTTATTGCAGCACGCACTCAG
+CAGCAAAATGGCTTACCTGCAAAAGAAGCTCATCGCTTTGCGGCAGTAGCGTTTAGAGAT
+GCTCAGGTCAAGCAGCTCAATAACCAGCCCTGGCAAACCATAAAAAATACACTCACGCAT
+AACGGGCATCACTATACCAACACGCAGCTCCCTGCCGCAGAGATGAAAATCGGCGCAAAA
+GATATCTTTCCCAGTGCTTATGAGGGAAAGGGCGTATGCAGTTGGGATACCAAGAATATT
+CATCACGCCAATAATTTGTGGATGTCCACGGTGAGTGTGCATGAGGACGGTAAAGATAAA
+ACGCTTTTTTGCGGGATACGTCATGGTGTGCTTTCCCCCTATCATGAAAAAGATCCGCTT
+CTGCGTCAGGCCGGCGCTGAAAACAAAGCCAAAGAAGTATTAGCTGCGGCACTTTTTAGT
+AAACCTGAGTTGCTTAACAGAGCCTTAGAGGGCGAAGCGGTAAGCCTGAAACTGGTATCC
+GTCGGGTTACTCACCGCGTCGAATATTTTCGGCAAAGAGGGAACTATGGTCGAGGATCAA
+ATGCGCGCATGGCAATCGTTGACCCAGCCGGGAAAAATGATTCATTTAAAAATCCGCAAT
+AAAGATGGCGATCTACAGACGGTAAAAATAAAACCGGACGTCGCCGCATTTAATGTGGGT
+GTTAATGAGCTGGCGCTCAAGCTCGGCTTTGGCCTTAAAGCATCAGATAGCTATAATGCC
+GAAGCGCTACATCAGTTATTAGGCAATGATTTACGCCCTGAAGCCAGACCAGGTGGCTGG
+GTTGGCGAATGGCTGGCGCAATACCCGGATAATTATGAGGTCGTCAATACATTAGCGCGC
+CAGATTAAGGATATCTGGAAAAATAACCAACATCATAAAGATGGCGGCGAACCCTATAAA
+CTCGCACAACGCCTTGCCATGTTAGCCCATGAAATTGACGCGGTGCCCGCCTGGAATTGT
+AAAAGCGGCAAAGATCGTACAGGGATGATGGATTCAGAAATCAAGCGAGAGCTCATTTCT
+TTCCATCAGACCCATATGTTAAGTGCGCCTGGTAGTCTTCCGGATAGCGGTGGACAGAAA
+ATTTTCCAAAAAGTATTACTGAATAGCGGTAACCTGGAGATTCAGAAACAAAATACGGGC
+GGGGCGGGAAACAAAGTAATGAAAAATTTATCGCCAGAGGTGCTCAATCTTTCCTATCAA
+AAACGAGTTGGGGATGAAAATATTTGGCAGTCAGTAAAAGGTATTTCTTCATTAATCACA
+TCT
\ No newline at end of file
diff --git a/t/data/out_of_order_fasta.fa b/t/data/out_of_order_fasta.fa
new file mode 100644
index 0000000..13f02f9
--- /dev/null
+++ b/t/data/out_of_order_fasta.fa
@@ -0,0 +1,10 @@
+>5555
+AAAAAAA
+>3333
+GGGGGGG
+>4444
+CCCCCCC
+>2222
+TTTTTTT
+>1111
+AAAAAAA
diff --git a/t/data/out_of_order_fasta.fa.sorted.fa b/t/data/out_of_order_fasta.fa.sorted.fa
new file mode 100644
index 0000000..56ce040
--- /dev/null
+++ b/t/data/out_of_order_fasta.fa.sorted.fa
@@ -0,0 +1,10 @@
+>1111
+AAAAAAA
+>2222
+TTTTTTT
+>3333
+GGGGGGG
+>4444
+CCCCCCC
+>5555
+AAAAAAA
diff --git a/t/data/overall_gene_presence_absence.csv b/t/data/overall_gene_presence_absence.csv
new file mode 100644
index 0000000..d828265
--- /dev/null
+++ b/t/data/overall_gene_presence_absence.csv
@@ -0,0 +1,22 @@
+"Gene","Non-unique Gene name","Annotation","No. isolates","No. sequences","Avg sequences per isolate","Genome Fragment","Order within Fragment","Accessory Fragment","Accessory Order with Fragment","QC","Min group size nuc","Max group size nuc","Avg group size nuc","query_1","query_2","query_5"
+"hly","","Alpha-toxin","2","2","1","1","1","1","7","","959","959","959","1_1","2_1___1",""
+"group_10","","hypothetical protein","2","2","1","1","10","1","6","","227","227","227","abc_00010","abc_00010___10",""
+"group_11","","C4-dicarboxylate transporter/malic acid transport protein","2","2","1","1","11","1","5","","947","947","947","abc_00011","abc_00011___11",""
+"group_12","","hypothetical protein","2","2","1","1","12","1","4","","188","188","188","abc_00012","abc_00012___12",""
+"group_13","","Gonococcal growth inhibitor III","2","2","1","1","13","1","3","","134","134","134","abc_00014","abc_00014___14",""
+"group_14","","Gonococcal growth inhibitor III","2","2","1","1","14","1","2","","134","134","134","1_6","2_7___15",""
+"yfnB","","Putative HAD-hydrolase yfnB","2","2","1","1","15","1","1","","686","686","686","abc_00016","abc_00016___16",""
+"group_2","","hypothetical protein","2","2","1","1","2","1","8","","146","146","146","abc_00002","abc_00002___2",""
+"group_3","","hypothetical protein","2","2","1","1","3","1","9","","197","197","197","abc_00003","abc_00003___3",""
+"group_4","","superantigen-like protein","2","2","1","1","4","1","10","","716","716","716","abc_00004","abc_00004___4",""
+"speH","","hypothetical protein","2","2","1","1","5","1","11","","725","725","725","1_2","2_2___5",""
+"group_6","","superantigen-like protein","2","2","1","1","6","1","12","","725","725","725","abc_00006","abc_00006___6",""
+"argF","","Ornithine carbamoyltransferase","2","2","1","1","7","1","13","","1001","1001","1001","1_3","2_3___7",""
+"arcC1","","Carbamate kinase 1","2","2","1","1","8","1","14","","935","935","935","abc_00008","abc_00008___8",""
+"group_9","","16S ribosomal RNA","2","2","1","1","9","1","15","","1556","1556","1556","abc_01705","abc_01705___9",""
+"group_16","","hypothetical protein","1","1","1","2","1","2","6","","146","146","146","","","abc_50002"
+"group_17","argF","Ornithine carbamoyltransferase","1","1","1","2","6","2","5","","1001","1001","1001","","","3_3"
+"group_18","","hypothetical protein","1","1","1","2","5","2","4","","227","227","227","","","abc_50010"
+"group_19","","hypothetical protein","1","1","1","2","4","2","3","","188","188","188","","","abc_50012"
+"group_20","","Gonococcal growth inhibitor III","1","1","1","2","3","2","2","","134","134","134","","","abc_50014"
+"group_21","yfnB","Putative HAD-hydrolase yfnB","1","1","1","2","2","2","1","","686","686","686","","","3_5"
diff --git a/t/data/pan_genome_sequences/argF.fa b/t/data/pan_genome_sequences/argF.fa
new file mode 100644
index 0000000..fc60aab
--- /dev/null
+++ b/t/data/pan_genome_sequences/argF.fa
@@ -0,0 +1,36 @@
+>1_3
+ATGAAAAATTTACGAAACAGAAGTTTTTTAACTTTATTAGACTTTTCACGACAAGAGGTA
+GAATTCTTATTAACACTCTCCGAGGATTTAAAACGTGCTAAATATATTGGCACTGAAAAG
+CCTATGTTAAAAAATAAAAATATTGCACTGTTATTTGAAAAAGATTCTACAAGAACGCGA
+TGTGCATTTGAAGTTGCAGCGCATGATCAAGGTGCAAATGTAACTTATTTAGGCCCAACT
+GGATCACAAATGGGTAAAAAAGAAACAACTAAAGATACTGCACGTGTGCTTGGTGGAATG
+TATGATGGCATTGAATACCGTGGTTTTTCACAAAGAACAGTAGAAACTTTAGCTGAAAAT
+TCAGGCGTACCAGTGTGGAATGGTTTAACTGATGAAGATCATCCTACTCAAGTTCTTGCT
+GATTTCTTAACAGCAAAAGAAGTCTTAAAAAAAGATTATGCAGATATTAACTTTACATAT
+GTTGGAGATGGTCGTAATAACGTTGCAAATGCATTAATGCAAGGTGCTGCCATTATGGGT
+ATGAACTTCCATTTAGTTTGTCCAAAAGAATTAAATCCAACAGATGAATTATTAAATCGC
+TGTAAAAATATTGCCGCTGAAAATGGTGGCAACATATTAATCACAGATGATATTGACCAA
+GGTGTAAAAGGTTCGGATGTAATTTACACTGATGTTTGGGTATCAATGGGTGAACCTGAT
+GAAGTATGGAAAGAACGACTTGAATTATTGAAACCATATCAAGTAAATAAAGAAATGATG
+GATAAAACTGGTAATCCAAATGTTATTTTTGAGCATTGCTTACCATCTTTCCATAATGCT
+GATACGAAAATTGGTCAACAAATTTTTGAAAAATATGGTATTCGAGAAATGGAAGTTACA
+GATGAAGTATTCGAAAGTAAAGCTTCAGTTGTATTCCAAGAAGCTGAGAACAGAATGCAT
+ACAATCAAAGCAGTCATGGTTGCTACATTGGGTGAATTTTAA
+>3_3
+ATGAAAAATTTACGAAACAGAAGTTTTTTAACTTTATTAGACTTTTCACGACAAGAGGTA
+GAATTCTTATTAACACTCTCCGAGGATTTAAAACGTGCTAAATATATTGGCACTGAAAAG
+CCTATGTTAAAAAATAAAAATATTGCACTGTTATTTGAAAAAGATTCTACAAGAACGCGA
+TGTGCATTTGAAGTTGCAGCGCATGATCAAGGTGCAAATGTAACTTATTTAGGCCCAACT
+GGATCACAAATGGGTAAAAAAGAAACAACTAAAGATACTGCACGTGTGCTTGGTGGAATG
+TATGATGGCATTGAATACCGTGGTTTTTCACAAAGAACAGTAGAAACTTTAGCTGAAAAT
+TCAGGCGTACCAGTGTGGAATGGTTTAACTGATGAAGATCATCCTACTCAAGTTCTTGCT
+GATTTCTTAACAGCAAAAGAAGTCTTAAAAAAAGATTATGCAGATATTAACTTTACATAT
+GTTGGAGATGGTCGTAATAACGTTGCAAATGCATTAATGCAAGGTGCTGCCATTATGGGT
+ATGAACTTCCATTTAGTTTGTCCAAAAGAATTAAATCCAACAGATGAATTATTAAATCGC
+TGTAAAAATATTGCCGCTGAAAATGGTGGCAACATATTAATCACAGATGATATTGACCAA
+GGTGTAAAAGGTTCGGATGTAATTTACACTGATGTTTGGGTATCAATGGGTGAACCTGAT
+GAAGTATGGAAAGAACGACTTGAATTATTGAAACCATATCAAGTAAATAAAGAAATGATG
+GATAAAACTGGTAATCCAAATGTTATTTTTGAGCATTGCTTACCATCTTTCCATAATGCT
+GATACGAAAATTGGTCAACAAATTTTTGAAAAATATGGTATTCGAGAAATGGAAGTTACA
+GATGAAGTATTCGAAAGTAAAGCTTCAGTTGTATTCCAAGAAGCTGAGAACAGAATGCAT
+ACAATCAAAGCAGTCATGGTTGCTACATTGGGTGAATTTTAA
diff --git a/t/data/pan_genome_sequences/hly.fa b/t/data/pan_genome_sequences/hly.fa
new file mode 100644
index 0000000..777b60f
--- /dev/null
+++ b/t/data/pan_genome_sequences/hly.fa
@@ -0,0 +1,51 @@
+>1_1
+ATGAAAACACGTATAGTCAGCTCAGTAACAACAACACTATTGCTAGGTTCCATATTAATG
+AATCCTGTCGCTAATGCCGCAGATTCTGATATTAATATTAAAACCGGTACTACAGATATT
+GGAAGCAATACTACAGTAAAAACAGGTGATTTAGTCACTTATGATAAAGAAAATGGCATG
+CACAAAAAAGTATTTTATAGTTTTATCGATGATAAAAATCACAATAAAAAACTGCTAGTT
+ATTAGAACGAAAGGTACCATTGCTGGTCAATATAGAGTTTATAGCGAAGAAGGTGCTAAC
+AAAAGTGGTTTAGCCTGGCCTTCAGCCTTTAAGGTACAGTTGCAACTACCTGATAATGAA
+GTAGCTCAAATATCTGATTACTATCCAAGAAATTCGATTGATACAAAAGAGTATATGAGT
+ACTTTAACTTATGGATTCAACGGTAATGTTACTGGTGATGATACAGGAAAAATTGGCGGC
+CTTATTGGTGCAAATGTTTCGATTGGTCATACACTGAAATATGTTCAACCTGATTTCAAA
+ACAATTTTAGAGAGCCCAACTGATAAAAAAGTAGGCTGGAAAGTGATATTTAACAATATG
+GTGAATCAAAATTGGGGACCATATGATAGAGATTCTTGGAACCCGGTATATGGCAATCAA
+CTTTTCATGAAAACTAGAAATGGTTCTATGAAAGCAGCAGAGAACTTCCTTGATCCTAAC
+AAAGCAAGTTCTCTATTATCTTCAGGGTTTTCACCAGACTTCGCTACAGTTATTACTATG
+GATAGAAAAGCATCCAAACAACAAACAAATATAGATGTAATATACGAACGAGTTCGTGAT
+GACTACCAATTGCATTGGACTTCAACAAATTGGAAAGGTACCAATACTAAAGATAAATGG
+ACAGATCGTTCTTCAGAAAGATATAAAATCGATTGGGAAAAAGAAGAAATGACAAATTAA
+>2_1
+ATGAAAACACGTATAGTCAGCTCAGTAACAACAACACTATTGCTAGGTTCCATATTAATG
+AATCCTGTCGCTAATGCCGCAGATTCTGATATTAATATTAAAACCGGTACTACAGATATT
+GGAAGCAATACTACAGTAAAAACAGGTGATTTAGTCACTTATGATAAAGAAAATGGCATG
+CACAAAAAAGTATTTTATAGTTTTATCGATGATAAAAATCACAATAAAAAACTGCTAGTT
+ATTAGAACGAAAGGTACCATTGCTGGTCAATATAGAGTTTATAGCGAAGAAGGTGCTAAC
+AAAAGTGGTTTAGCCTGGCCTTCAGCCTTTAAGGTACAGTTGCAACTACCTGATAATGAA
+GTAGCTCAAATATCTGATTACTATCCAAGAAATTCGATTGATACAAAAGAGTATATGAGT
+ACTTTAACTTATGGATTCAACGGTAATGTTACTGGTGATGATACAGGAAAAATTGGCGGC
+CTTATTGGTGCAAATGTTTCGATTGGTCATACACTGAAATATGTTCAACCTGATTTCAAA
+ACAATTTTAGAGAGCCCAACTGATAAAAAAGTAGGCTGGAAAGTGATATTTAACAATATG
+GTGAATCAAAATTGGGGACCATATGATAGAGATTCTTGGAACCCGGTATATGGCAATCAA
+CTTTTCATGAAAACTAGAAATGGTTCTATGAAAGCAGCAGAGAACTTCCTTGATCCTAAC
+AAAGCAAGTTCTCTATTATCTTCAGGGTTTTCACCAGACTTCGCTACAGTTATTACTATG
+GATAGAAAAGCATCCAAACAACAAACAAATATAGATGTAATATACGAACGAGTTCGTGAT
+GACTACCAATTGCATTGGACTTCAACAAATTGGAAAGGTACCAATACTAAAGATAAATGG
+ACAGATCGTTCTTCAGAAAGATATAAAATCGATTGGGAAAAAGAAGAAATGACAAATTAA
+>3_1
+ATGAAAACACGTATAGTCAGCTCAGTAACAACAACACTATTGCTAGGTTCCATATTAATG
+AATCCTGTCGCTAATGCCGCAGATTCTGATATTAATATTAAAACCGGTACTACAGATATT
+GGAAGCAATACTACAGTAAAAACAGGTGATTTAGTCACTTATGATAAAGAAAATGGCATG
+CACAAAAAAGTATTTTATAGTTTTATCGATGATAAAAATCACAATAAAAAACTGCTAGTT
+ATTAGAACGAAAGGTACCATTGCTGGTCAATATAGAGTTTATAGCGAAGAAGGTGCTAAC
+AAAAGTGGTTTAGCCTGGCCTTCAGCCTTTAAGGTACAGTTGCAACTACCTGATAATGAA
+GTAGCTCAAATATCTGATTACTATCCAAGAAATTCGATTGATACAAAAGAGTATATGAGT
+ACTTTAACTTATGGATTCAACGGTAATGTTACTGGTGATGATACAGGAAAAATTGGCGGC
+CTTATTGGTGCAAATGTTTCGATTGGTCATACACTGAAATATGTTCAACCTGATTTCAAA
+ACAATTTTAGAGAGCCCAACTGATAAAAAAGTAGGCTGGAAAGTGATATTTAACAATATG
+GTGAATCAAAATTGGGGACCATATGATAGAGATTCTTGGAACCCGGTATATGGCAATCAA
+CTTTTCATGAAAACTAGAAATGGTTCTATGAAAGCAGCAGAGAACTTCCTTGATCCTAAC
+AAAGCAAGTTCTCTATTATCTTCAGGGTTTTCACCAGACTTCGCTACAGTTATTACTATG
+GATAGAAAAGCATCCAAACAACAAACAAATATAGATGTAATATACGAACGAGTTCGTGAT
+GACTACCAATTGCATTGGACTTCAACAAATTGGAAAGGTACCAATACTAAAGATAAATGG
+ACAGATCGTTCTTCAGAAAGATATAAAATCGATTGGGAAAAAGAAGAAATGACAAATTAA
diff --git a/t/data/pan_genome_sequences/speH.fa b/t/data/pan_genome_sequences/speH.fa
new file mode 100644
index 0000000..2e8dc9d
--- /dev/null
+++ b/t/data/pan_genome_sequences/speH.fa
@@ -0,0 +1,28 @@
+>1_2
+ATGAACAATAACATCACGAAAAAAATTATTTTATCAACAACATTGTTACTATTAGGTACA
+GCATTTACACAATTTCCTAATACACCTATCAATTCTTCATCTGAAGCGAAAGCTTATTAT
+ATAAATCAAAACGAAACTAACGTTAATGAGTTAACTAAATATTACTCGCAAAAATATTTA
+ACCTTCTCTAACAGTACGTTATGGCAAAAAGATAACGGTACGATTCATGCAACGTTGTTA
+CAGTTTTCTTGGTATAGTCATATTCAAGTTTATGGACCTGAAAGTTGGGGCAATATCAAC
+CAATTAAGAAATAAAAGCGTTGATATTTTTGGCATAAAAGACCAAGAAACCATTGATTCT
+TTTGCATTATCTCAAGAAACGTTTACTGGTGGTGTTACTCCTGCAGCAACATCTAACGAT
+AAACACTATAAACTGAATGTAACATATAAAGATAAAGCAGAAACGTTTACTGGCGGATTT
+CCAGTTTATGAAGGCAATAAGCCTGTTTTAACTTTAAAAGAATTAGATTTTCGTATTCGT
+CAAACATTAATTAAAAGTAAAAAATTATATAATAATTCTTATAATAAAGGACAAATTAAA
+ATAACAGGTACAGACAATAACTACACAATAGATTTAAGTAAAAGGTTGCCATCAACTGAT
+GCAAATAGATATGTTAAAAAACCTCAAAATGCAAAAATTGAAGTTATCCTCGAAAAATCA
+AACTAA
+>2_2
+ATGAACAATAACATCACGAAAAAAATTATTTTATCAACAACATTGTTACTATTAGGTACA
+GCATTTACACAATTTCCTAATACACCTATCAATTCTTCATCTGAAGCGAAAGCTTATTAT
+ATAAATCAAAACGAAACTAACGTTAATGAGTTAACTAAATATTACTCGCAAAAATATTTA
+ACCTTCTCTAACAGTACGTTATGGCAAAAAGATAACGGTACGATTCATGCAACGTTGTTA
+CAGTTTTCTTGGTATAGTCATATTCAAGTTTATGGACCTGAAAGTTGGGGCAATATCAAC
+CAATTAAGAAATAAAAGCGTTGATATTTTTGGCATAAAAGACCAAGAAACCATTGATTCT
+TTTGCATTATCTCAAGAAACGTTTACTGGTGGTGTTACTCCTGCAGCAACATCTAACGAT
+AAACACTATAAACTGAATGTAACATATAAAGATAAAGCAGAAACGTTTACTGGCGGATTT
+CCAGTTTATGAAGGCAATAAGCCTGTTTTAACTTTAAAAGAATTAGATTTTCGTATTCGT
+CAAACATTAATTAAAAGTAAAAAATTATATAATAATTCTTATAATAAAGGACAAATTAAA
+ATAACAGGTACAGACAATAACTACACAATAGATTTAAGTAAAAGGTTGCCATCAACTGAT
+GCAAATAGATATGTTAAAAAACCTCAAAATGCAAAAATTGAAGTTATCCTCGAAAAATCA
+AACTAA
diff --git a/t/data/post_analysis/_clustered.clstr b/t/data/post_analysis/_clustered.clstr
new file mode 100644
index 0000000..6c1d1b2
--- /dev/null
+++ b/t/data/post_analysis/_clustered.clstr
@@ -0,0 +1,55 @@
+>Cluster 0
+0 518aa, >abc_01705... *
+1 518aa, >abc_01705... at 100.00%
+>Cluster 1
+0 333aa, >1_3... *
+1 333aa, >2_3... at 100.00%
+>Cluster 2
+0 333aa, >3_3... *
+>Cluster 3
+0 319aa, >1_1... *
+1 319aa, >2_1... at 100.00%
+>Cluster 4
+0 315aa, >abc_00011... *
+1 315aa, >abc_00011... at 100.00%
+>Cluster 5
+0 311aa, >abc_00008... *
+1 311aa, >abc_00008... at 100.00%
+>Cluster 6
+0 241aa, >1_2... *
+1 241aa, >2_2... at 100.00%
+>Cluster 7
+0 241aa, >abc_00006... *
+1 241aa, >abc_00006... at 100.00%
+>Cluster 8
+0 238aa, >abc_00004... *
+1 238aa, >abc_00004... at 100.00%
+>Cluster 9
+0 228aa, >abc_00016... *
+1 228aa, >abc_00016... at 100.00%
+>Cluster 10
+0 228aa, >3_5... *
+>Cluster 11
+0 75aa, >abc_00010... *
+1 75aa, >abc_00010... at 100.00%
+>Cluster 12
+0 65aa, >abc_00003... *
+1 65aa, >abc_00003... at 100.00%
+>Cluster 13
+0 62aa, >abc_00012... *
+1 62aa, >abc_00012... at 100.00%
+>Cluster 14
+0 62aa, >abc_00012... *
+>Cluster 15
+0 49aa, >abc_00002... *
+>Cluster 16
+0 48aa, >abc_00002... *
+1 48aa, >abc_00002... at 100.00%
+>Cluster 17
+0 45aa, >abc_00014... *
+>Cluster 18
+0 44aa, >abc_00014... *
+1 44aa, >abc_00014... at 100.00%
+>Cluster 19
+0 44aa, >1_6... *
+1 44aa, >2_7... at 100.00%
diff --git a/t/data/post_analysis/_combined_files b/t/data/post_analysis/_combined_files
new file mode 100644
index 0000000..12a43ec
--- /dev/null
+++ b/t/data/post_analysis/_combined_files
@@ -0,0 +1,169 @@
+>1_1
+MKTRIVSSVTTTLLLGSILMNPVANAADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGM
+HKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNE
+VAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFK
+TILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAAENFLDPN
+KASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKW
+TDRSSERYKIDWEKEEMTN*
+>abc_00002
+MKLFYIVFLIIIWLNIFLGNEIIHTLTVLITTLYIVNSRKGIKNDRVE*
+>abc_00003
+MTELNNIINSLQSLFESESGYKISKNSGVPYQTVQDLRNGKTKLEDARFRTIIKLYSYYV
+SLKEH*
+>abc_00004
+MSKNITKNIILTTTLLLLGTVLPQNQKPVFSFYSEAKAYSIGQDETNINELIKYYTQPHF
+SFSNKWLYQYDNGNIYVELKRYSWSAHISLWGAESWGNINQLKDRYVDVFGLKDKDTDQL
+WWSYRETFTGGVTPAAKPSDKTYNLFVQYKDKLQTIIGAHKIYQGNKPVLTLKEIDFRAR
+EALIKNKILYTENRNKGKLKITGGGNNYTIDLSKRLHSDLANVYVKNPNKITVDVLFD*
+>1_2
+MNNNITKKIILSTTLLLLGTAFTQFPNTPINSSSEAKAYYINQNETNVNELTKYYSQKYL
+TFSNSTLWQKDNGTIHATLLQFSWYSHIQVYGPESWGNINQLRNKSVDIFGIKDQETIDS
+FALSQETFTGGVTPAATSNDKHYKLNVTYKDKAETFTGGFPVYEGNKPVLTLKELDFRIR
+QTLIKSKKLYNNSYNKGQIKITGTDNNYTIDLSKRLPSTDANRYVKKPQNAKIEVILEKS
+N*
+>abc_00006
+MKKNIMNKLVLSTALLLLGTTSTQLPKTPISFSSEAKAYNISENETNINELIKYYTQPHF
+SLSGKWLWQKPNGSIHATLQTWVWYSHIQVFGSESWGNINQLRNKYVDIFGTKDEDTVEG
+YWTYDETFTGGVTPAATSSDKPYRLFLKYSDKQQTIIGGHEFYKGNKPVLTLKELDFRIR
+QTLIKNKKLYNGEFNKGQIKITADGNNYTIDLSKKLKLTDTNRYVKNPKNAQIEVILEKS
+N*
+>1_3
+MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTR
+CAFEVAAHDQGANVTYLGPTGSQMGKKETTKDTARVLGGMYDGIEYRGFSQRTVETLAEN
+SGVPVWNGLTDEDHPTQVLADFLTAKEVLKKDYADINFTYVGDGRNNVANALMQGAAIMG
+MNFHLVCPKELNPTDELLNRCKNIAAENGGNILITDDIDQGVKGSDVIYTDVWVSMGEPD
+EVWKERLELLKPYQVNKEMMDKTGNPNVIFEHCLPSFHNADTKIGQQIFEKYGIREMEVT
+DEVFESKASVVFQEAENRMHTIKAVMVATLGEF*
+>abc_00008
+MMAKIVVALGGNALGKSPQEQLELVKNTAKSLVGLITKGHEIVISHGNGPQVGSINLGLN
+YAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVDENDPA
+FNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVPSPQPISIIELESIKTLIKN
+DTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDYVYINF
+NTENQQPLKTTNVDELKRYIDENQFAKGSMLPKIEAAISFIENNPKGSVLITSLNELDAA
+LEGKVGTVIKK*
+>abc_01705
+VENTINESEKKKRFKLKMPGAFMILFILTVVAVIATWVIPAGAYSKLSYEPSSQELKIVN
+PHNQVKKVPGTQQELDKMGVKIKIEQFKSGAINKPVSIPNTYERLKQHPAGPEQITSSMV
+EGTIEAVDIMVFILVLGGLIGVVQASGSFESGLLALTKKTKGHEFMLIVFVSILMIIGGT
+LCGIEEEAVAFYPILVPIFIALGYDSIVSVGAIFLASSVGSTFSTINPFSVVIASNAAGT
+TFTDGLYWRIGACIVGAIFVISYLYWYCKKIKNDPKASYSYEDKDAFEQQWSVLKDDDSA
+HFTLRKKIILTLFVLPFPIMVWGVMTQGWWFPVMASAFLIFTIIIMFIAGTGKSGLGEKG
+TVDAFVNGASSLVGVSLIIGLARGINLVLNEGMISDTILHFSSSLVQHMSGPLFIIVLLF
+IFFCLGFIVPSSSGLAVLSMPIFAPLADTVGIPRFVIVTTYQFGQYAMLFLAPTGLVMAT
+LQMLNMRYSHWFRFVWPVVAFVLIFGGGVLITQVLIYS*
+>abc_00010
+MTHLTKVLDTLTGICVVLLFSKYFVAYANMVFDWNLRWYLLENIPHLPIILFILMFIFGV
+PSEMIKDRQRKNNGV*
+>abc_00011
+MRLQKAPLVTSGLVLGLLGLGNLLKDLSLTLNAVCGIFAFLIWIHLLCTMIKYFNNVKEQ
+LNSPLVSSVFTTFFMSGFLGTTYLNTFFSNITFINSLITPIWILCLVGIMTHMIIFSIKY
+LKDFSLENVYPSWTVLFIGIAIAGLTAPVSGCFFIGQLTVIYGFVATCIVLPIVFKRLKA
+FPLQTSIKPNTSTICAPFSLVAAAYVIAFPKANAFIVIIFLILAQIFYFYIIIQLPKLLK
+EPFSPVFSAFTFPLVISATALKNSLPVLMFPDIWKGLLFIEVLLATVIVLRVFIGYLHFF
+LKKENQDKFLRNASQ*
+>abc_00012
+MRNQIQKLLDSDLSSLHISKQTGVPQSTIHRMRKKERSLDNMSLKNAELLYKFANSIFSN
+EN*
+>abc_00014
+MEGLFNAIKDTVTAAINNDGAKLGTSIVSIVENGVGLLGKLFGF*
+>1_6
+MTGLAEAIANTVQAAQQHDSVKLGTSIVDIVANGVGLLGKLFGF*
+>abc_00016
+LGYKNILIDFDDTIVDFYDAEEWAFHYMANVFNHKATKDDFLTFKKINHQHWEAFQQNKL
+TKSEVLSERFVNYFKHHQMEVDGHRADVLFRNGLAEAKVKYFDQTLETIVELSKRHDLYI
+VTNGVTETQKRRLNQTPLHKYIKKIFISEETGYQKPNPEFFNYVFNDIGEDERQHSIIVG
+DSLTSDILGGINAGIATCWFNFRGFDHNPGIIPDYEINSWKQLNDIVR*
+>2_1
+MKTRIVSSVTTTLLLGSILMNPVANAADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGM
+HKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNE
+VAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFK
+TILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAAENFLDPN
+KASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKW
+TDRSSERYKIDWEKEEMTN*
+>abc_00002
+MKLFYIVFLIIIWLNIFLGNEIIHTLTVLITTLYIVNSRKGIKNDRVE*
+>abc_00003
+MTELNNIINSLQSLFESESGYKISKNSGVPYQTVQDLRNGKTKLEDARFRTIIKLYSYYV
+SLKEH*
+>abc_00004
+MSKNITKNIILTTTLLLLGTVLPQNQKPVFSFYSEAKAYSIGQDETNINELIKYYTQPHF
+SFSNKWLYQYDNGNIYVELKRYSWSAHISLWGAESWGNINQLKDRYVDVFGLKDKDTDQL
+WWSYRETFTGGVTPAAKPSDKTYNLFVQYKDKLQTIIGAHKIYQGNKPVLTLKEIDFRAR
+EALIKNKILYTENRNKGKLKITGGGNNYTIDLSKRLHSDLANVYVKNPNKITVDVLFD*
+>2_2
+MNNNITKKIILSTTLLLLGTAFTQFPNTPINSSSEAKAYYINQNETNVNELTKYYSQKYL
+TFSNSTLWQKDNGTIHATLLQFSWYSHIQVYGPESWGNINQLRNKSVDIFGIKDQETIDS
+FALSQETFTGGVTPAATSNDKHYKLNVTYKDKAETFTGGFPVYEGNKPVLTLKELDFRIR
+QTLIKSKKLYNNSYNKGQIKITGTDNNYTIDLSKRLPSTDANRYVKKPQNAKIEVILEKS
+N*
+>abc_00006
+MKKNIMNKLVLSTALLLLGTTSTQLPKTPISFSSEAKAYNISENETNINELIKYYTQPHF
+SLSGKWLWQKPNGSIHATLQTWVWYSHIQVFGSESWGNINQLRNKYVDIFGTKDEDTVEG
+YWTYDETFTGGVTPAATSSDKPYRLFLKYSDKQQTIIGGHEFYKGNKPVLTLKELDFRIR
+QTLIKNKKLYNGEFNKGQIKITADGNNYTIDLSKKLKLTDTNRYVKNPKNAQIEVILEKS
+N*
+>2_3
+MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTR
+CAFEVAAHDQGANVTYLGPTGSQMGKKETTKDTARVLGGMYDGIEYRGFSQRTVETLAEN
+SGVPVWNGLTDEDHPTQVLADFLTAKEVLKKDYADINFTYVGDGRNNVANALMQGAAIMG
+MNFHLVCPKELNPTDELLNRCKNIAAENGGNILITDDIDQGVKGSDVIYTDVWVSMGEPD
+EVWKERLELLKPYQVNKEMMDKTGNPNVIFEHCLPSFHNADTKIGQQIFEKYGIREMEVT
+DEVFESKASVVFQEAENRMHTIKAVMVATLGEF*
+>abc_00008
+MMAKIVVALGGNALGKSPQEQLELVKNTAKSLVGLITKGHEIVISHGNGPQVGSINLGLN
+YAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVDENDPA
+FNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVPSPQPISIIELESIKTLIKN
+DTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDYVYINF
+NTENQQPLKTTNVDELKRYIDENQFAKGSMLPKIEAAISFIENNPKGSVLITSLNELDAA
+LEGKVGTVIKK*
+>abc_01705
+VENTINESEKKKRFKLKMPGAFMILFILTVVAVIATWVIPAGAYSKLSYEPSSQELKIVN
+PHNQVKKVPGTQQELDKMGVKIKIEQFKSGAINKPVSIPNTYERLKQHPAGPEQITSSMV
+EGTIEAVDIMVFILVLGGLIGVVQASGSFESGLLALTKKTKGHEFMLIVFVSILMIIGGT
+LCGIEEEAVAFYPILVPIFIALGYDSIVSVGAIFLASSVGSTFSTINPFSVVIASNAAGT
+TFTDGLYWRIGACIVGAIFVISYLYWYCKKIKNDPKASYSYEDKDAFEQQWSVLKDDDSA
+HFTLRKKIILTLFVLPFPIMVWGVMTQGWWFPVMASAFLIFTIIIMFIAGTGKSGLGEKG
+TVDAFVNGASSLVGVSLIIGLARGINLVLNEGMISDTILHFSSSLVQHMSGPLFIIVLLF
+IFFCLGFIVPSSSGLAVLSMPIFAPLADTVGIPRFVIVTTYQFGQYAMLFLAPTGLVMAT
+LQMLNMRYSHWFRFVWPVVAFVLIFGGGVLITQVLIYS*
+>abc_00010
+MTHLTKVLDTLTGICVVLLFSKYFVAYANMVFDWNLRWYLLENIPHLPIILFILMFIFGV
+PSEMIKDRQRKNNGV*
+>abc_00011
+MRLQKAPLVTSGLVLGLLGLGNLLKDLSLTLNAVCGIFAFLIWIHLLCTMIKYFNNVKEQ
+LNSPLVSSVFTTFFMSGFLGTTYLNTFFSNITFINSLITPIWILCLVGIMTHMIIFSIKY
+LKDFSLENVYPSWTVLFIGIAIAGLTAPVSGCFFIGQLTVIYGFVATCIVLPIVFKRLKA
+FPLQTSIKPNTSTICAPFSLVAAAYVIAFPKANAFIVIIFLILAQIFYFYIIIQLPKLLK
+EPFSPVFSAFTFPLVISATALKNSLPVLMFPDIWKGLLFIEVLLATVIVLRVFIGYLHFF
+LKKENQDKFLRNASQ*
+>abc_00012
+MRNQIQKLLDSDLSSLHISKQTGVPQSTIHRMRKKERSLDNMSLKNAELLYKFANSIFSN
+EN*
+>abc_00014
+MEGLFNAIKDTVTAAINNDGAKLGTSIVSIVENGVGLLGKLFGF*
+>2_7
+MTGLAEAIANTVQAAQQHDSVKLGTSIVDIVANGVGLLGKLFGF*
+>abc_00016
+LGYKNILIDFDDTIVDFYDAEEWAFHYMANVFNHKATKDDFLTFKKINHQHWEAFQQNKL
+TKSEVLSERFVNYFKHHQMEVDGHRADVLFRNGLAEAKVKYFDQTLETIVELSKRHDLYI
+VTNGVTETQKRRLNQTPLHKYIKKIFISEETGYQKPNPEFFNYVFNDIGEDERQHSIIVG
+DSLTSDILGGINAGIATCWFNFRGFDHNPGIIPDYEINSWKQLNDIVR*
+>abc_00002
+MKLFFIVSLTIIWGDIFLGNEIIHLLTALTTTLGVVNSRKGIKNFRVAQ
+>3_3
+LTNLRGGSFLTILDFSLQEAQSLLTGAEDLKSAKYIFTETPTLKNGDIALLIEKDSLRTP
+RAFEVGAHDQGTNVTYLGPTRSQMGGEETTKNTARVFGGTHAGIEGGGFSQRTVETLAET
+PAVPVGDGLTDKDHPTLVLAHSLTAGEVLKKNYADIFFTSLADGRGDVANAIMQGAFIMA
+LTFHLGGPKELNPTDDLLNPRTNIAGENGGNILITDFIDPRAKGSGVIYTDIWVSIFEPA
+QAWKEGVELLKTYQVNLEMTHTTGNGDVIFENCLPSFHNAHTKIGGEIFEKNGIRDLEVT
+HAVFEGEASVVIQEADFRMPPTKAVGVATLGKF*
+>abc_00012
+MRNQNQKLLFSDFPSLHIWGQTGVQQSTIFRMSPNERSWGNMSLKNAELFYKFPNSIFRG
+EN*
+>abc_00014
+MEGLFFAITHTVTAGVNNDGTKLGTFIVTLAENGGGLLGKIFGFY
+>3_5
+LGGKNILKDFDDFIVDPYDAEGGAFHYKANVFFHKAPNDDFWGFKKINHQHWFAFHPNKL
+TRGEVLSERFVNFFKHPHMEVGGHRADELFRNFLADPNVKYWGQTLEKIVELFKRHPFYI
+VRGGVTEKQKRRFNQTPFHKYRGKIFIYEETGFQKPPPEFFRGVFNDNGEDEFQHSPIVG
+DWGTSDIQGGINFGIAPCWFNWGGFDHNPGIIFDYDPNSWKRGNDIVH*
diff --git a/t/data/post_analysis/_combined_files.groups b/t/data/post_analysis/_combined_files.groups
new file mode 100644
index 0000000..e69de29
diff --git a/t/data/post_analysis/_fasta_files b/t/data/post_analysis/_fasta_files
new file mode 100644
index 0000000..f75f62d
--- /dev/null
+++ b/t/data/post_analysis/_fasta_files
@@ -0,0 +1,3 @@
+query_1.gff.proteome.faa
+query_2.gff.proteome.faa
+query_6.gff.proteome.faa
diff --git a/t/data/post_analysis/_gff_files b/t/data/post_analysis/_gff_files
new file mode 100644
index 0000000..2f2a360
--- /dev/null
+++ b/t/data/post_analysis/_gff_files
@@ -0,0 +1,3 @@
+t/data/query_1.gff
+t/data/query_2.gff
+t/data/query_6.gff
diff --git a/t/data/post_analysis/_uninflated_mcl_groups b/t/data/post_analysis/_uninflated_mcl_groups
new file mode 100644
index 0000000..e69de29
diff --git a/t/data/post_analysis/query_1.gff.proteome.faa b/t/data/post_analysis/query_1.gff.proteome.faa
new file mode 100644
index 0000000..e18fa65
--- /dev/null
+++ b/t/data/post_analysis/query_1.gff.proteome.faa
@@ -0,0 +1,75 @@
+>1_1
+MKTRIVSSVTTTLLLGSILMNPVANAADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGM
+HKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNE
+VAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFK
+TILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAAENFLDPN
+KASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKW
+TDRSSERYKIDWEKEEMTN*
+>abc_00002
+MKLFYIVFLIIIWLNIFLGNEIIHTLTVLITTLYIVNSRKGIKNDRVE*
+>abc_00003
+MTELNNIINSLQSLFESESGYKISKNSGVPYQTVQDLRNGKTKLEDARFRTIIKLYSYYV
+SLKEH*
+>abc_00004
+MSKNITKNIILTTTLLLLGTVLPQNQKPVFSFYSEAKAYSIGQDETNINELIKYYTQPHF
+SFSNKWLYQYDNGNIYVELKRYSWSAHISLWGAESWGNINQLKDRYVDVFGLKDKDTDQL
+WWSYRETFTGGVTPAAKPSDKTYNLFVQYKDKLQTIIGAHKIYQGNKPVLTLKEIDFRAR
+EALIKNKILYTENRNKGKLKITGGGNNYTIDLSKRLHSDLANVYVKNPNKITVDVLFD*
+>1_2
+MNNNITKKIILSTTLLLLGTAFTQFPNTPINSSSEAKAYYINQNETNVNELTKYYSQKYL
+TFSNSTLWQKDNGTIHATLLQFSWYSHIQVYGPESWGNINQLRNKSVDIFGIKDQETIDS
+FALSQETFTGGVTPAATSNDKHYKLNVTYKDKAETFTGGFPVYEGNKPVLTLKELDFRIR
+QTLIKSKKLYNNSYNKGQIKITGTDNNYTIDLSKRLPSTDANRYVKKPQNAKIEVILEKS
+N*
+>abc_00006
+MKKNIMNKLVLSTALLLLGTTSTQLPKTPISFSSEAKAYNISENETNINELIKYYTQPHF
+SLSGKWLWQKPNGSIHATLQTWVWYSHIQVFGSESWGNINQLRNKYVDIFGTKDEDTVEG
+YWTYDETFTGGVTPAATSSDKPYRLFLKYSDKQQTIIGGHEFYKGNKPVLTLKELDFRIR
+QTLIKNKKLYNGEFNKGQIKITADGNNYTIDLSKKLKLTDTNRYVKNPKNAQIEVILEKS
+N*
+>1_3
+MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTR
+CAFEVAAHDQGANVTYLGPTGSQMGKKETTKDTARVLGGMYDGIEYRGFSQRTVETLAEN
+SGVPVWNGLTDEDHPTQVLADFLTAKEVLKKDYADINFTYVGDGRNNVANALMQGAAIMG
+MNFHLVCPKELNPTDELLNRCKNIAAENGGNILITDDIDQGVKGSDVIYTDVWVSMGEPD
+EVWKERLELLKPYQVNKEMMDKTGNPNVIFEHCLPSFHNADTKIGQQIFEKYGIREMEVT
+DEVFESKASVVFQEAENRMHTIKAVMVATLGEF*
+>abc_00008
+MMAKIVVALGGNALGKSPQEQLELVKNTAKSLVGLITKGHEIVISHGNGPQVGSINLGLN
+YAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVDENDPA
+FNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVPSPQPISIIELESIKTLIKN
+DTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDYVYINF
+NTENQQPLKTTNVDELKRYIDENQFAKGSMLPKIEAAISFIENNPKGSVLITSLNELDAA
+LEGKVGTVIKK*
+>abc_01705
+VENTINESEKKKRFKLKMPGAFMILFILTVVAVIATWVIPAGAYSKLSYEPSSQELKIVN
+PHNQVKKVPGTQQELDKMGVKIKIEQFKSGAINKPVSIPNTYERLKQHPAGPEQITSSMV
+EGTIEAVDIMVFILVLGGLIGVVQASGSFESGLLALTKKTKGHEFMLIVFVSILMIIGGT
+LCGIEEEAVAFYPILVPIFIALGYDSIVSVGAIFLASSVGSTFSTINPFSVVIASNAAGT
+TFTDGLYWRIGACIVGAIFVISYLYWYCKKIKNDPKASYSYEDKDAFEQQWSVLKDDDSA
+HFTLRKKIILTLFVLPFPIMVWGVMTQGWWFPVMASAFLIFTIIIMFIAGTGKSGLGEKG
+TVDAFVNGASSLVGVSLIIGLARGINLVLNEGMISDTILHFSSSLVQHMSGPLFIIVLLF
+IFFCLGFIVPSSSGLAVLSMPIFAPLADTVGIPRFVIVTTYQFGQYAMLFLAPTGLVMAT
+LQMLNMRYSHWFRFVWPVVAFVLIFGGGVLITQVLIYS*
+>abc_00010
+MTHLTKVLDTLTGICVVLLFSKYFVAYANMVFDWNLRWYLLENIPHLPIILFILMFIFGV
+PSEMIKDRQRKNNGV*
+>abc_00011
+MRLQKAPLVTSGLVLGLLGLGNLLKDLSLTLNAVCGIFAFLIWIHLLCTMIKYFNNVKEQ
+LNSPLVSSVFTTFFMSGFLGTTYLNTFFSNITFINSLITPIWILCLVGIMTHMIIFSIKY
+LKDFSLENVYPSWTVLFIGIAIAGLTAPVSGCFFIGQLTVIYGFVATCIVLPIVFKRLKA
+FPLQTSIKPNTSTICAPFSLVAAAYVIAFPKANAFIVIIFLILAQIFYFYIIIQLPKLLK
+EPFSPVFSAFTFPLVISATALKNSLPVLMFPDIWKGLLFIEVLLATVIVLRVFIGYLHFF
+LKKENQDKFLRNASQ*
+>abc_00012
+MRNQIQKLLDSDLSSLHISKQTGVPQSTIHRMRKKERSLDNMSLKNAELLYKFANSIFSN
+EN*
+>abc_00014
+MEGLFNAIKDTVTAAINNDGAKLGTSIVSIVENGVGLLGKLFGF*
+>1_6
+MTGLAEAIANTVQAAQQHDSVKLGTSIVDIVANGVGLLGKLFGF*
+>abc_00016
+LGYKNILIDFDDTIVDFYDAEEWAFHYMANVFNHKATKDDFLTFKKINHQHWEAFQQNKL
+TKSEVLSERFVNYFKHHQMEVDGHRADVLFRNGLAEAKVKYFDQTLETIVELSKRHDLYI
+VTNGVTETQKRRLNQTPLHKYIKKIFISEETGYQKPNPEFFNYVFNDIGEDERQHSIIVG
+DSLTSDILGGINAGIATCWFNFRGFDHNPGIIPDYEINSWKQLNDIVR*
diff --git a/t/data/post_analysis/query_2.gff.proteome.faa b/t/data/post_analysis/query_2.gff.proteome.faa
new file mode 100644
index 0000000..e2abcb1
--- /dev/null
+++ b/t/data/post_analysis/query_2.gff.proteome.faa
@@ -0,0 +1,75 @@
+>2_1
+MKTRIVSSVTTTLLLGSILMNPVANAADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGM
+HKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNE
+VAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFK
+TILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAAENFLDPN
+KASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKW
+TDRSSERYKIDWEKEEMTN*
+>abc_00002
+MKLFYIVFLIIIWLNIFLGNEIIHTLTVLITTLYIVNSRKGIKNDRVE*
+>abc_00003
+MTELNNIINSLQSLFESESGYKISKNSGVPYQTVQDLRNGKTKLEDARFRTIIKLYSYYV
+SLKEH*
+>abc_00004
+MSKNITKNIILTTTLLLLGTVLPQNQKPVFSFYSEAKAYSIGQDETNINELIKYYTQPHF
+SFSNKWLYQYDNGNIYVELKRYSWSAHISLWGAESWGNINQLKDRYVDVFGLKDKDTDQL
+WWSYRETFTGGVTPAAKPSDKTYNLFVQYKDKLQTIIGAHKIYQGNKPVLTLKEIDFRAR
+EALIKNKILYTENRNKGKLKITGGGNNYTIDLSKRLHSDLANVYVKNPNKITVDVLFD*
+>2_2
+MNNNITKKIILSTTLLLLGTAFTQFPNTPINSSSEAKAYYINQNETNVNELTKYYSQKYL
+TFSNSTLWQKDNGTIHATLLQFSWYSHIQVYGPESWGNINQLRNKSVDIFGIKDQETIDS
+FALSQETFTGGVTPAATSNDKHYKLNVTYKDKAETFTGGFPVYEGNKPVLTLKELDFRIR
+QTLIKSKKLYNNSYNKGQIKITGTDNNYTIDLSKRLPSTDANRYVKKPQNAKIEVILEKS
+N*
+>abc_00006
+MKKNIMNKLVLSTALLLLGTTSTQLPKTPISFSSEAKAYNISENETNINELIKYYTQPHF
+SLSGKWLWQKPNGSIHATLQTWVWYSHIQVFGSESWGNINQLRNKYVDIFGTKDEDTVEG
+YWTYDETFTGGVTPAATSSDKPYRLFLKYSDKQQTIIGGHEFYKGNKPVLTLKELDFRIR
+QTLIKNKKLYNGEFNKGQIKITADGNNYTIDLSKKLKLTDTNRYVKNPKNAQIEVILEKS
+N*
+>2_3
+MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTR
+CAFEVAAHDQGANVTYLGPTGSQMGKKETTKDTARVLGGMYDGIEYRGFSQRTVETLAEN
+SGVPVWNGLTDEDHPTQVLADFLTAKEVLKKDYADINFTYVGDGRNNVANALMQGAAIMG
+MNFHLVCPKELNPTDELLNRCKNIAAENGGNILITDDIDQGVKGSDVIYTDVWVSMGEPD
+EVWKERLELLKPYQVNKEMMDKTGNPNVIFEHCLPSFHNADTKIGQQIFEKYGIREMEVT
+DEVFESKASVVFQEAENRMHTIKAVMVATLGEF*
+>abc_00008
+MMAKIVVALGGNALGKSPQEQLELVKNTAKSLVGLITKGHEIVISHGNGPQVGSINLGLN
+YAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVDENDPA
+FNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVPSPQPISIIELESIKTLIKN
+DTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDYVYINF
+NTENQQPLKTTNVDELKRYIDENQFAKGSMLPKIEAAISFIENNPKGSVLITSLNELDAA
+LEGKVGTVIKK*
+>abc_01705
+VENTINESEKKKRFKLKMPGAFMILFILTVVAVIATWVIPAGAYSKLSYEPSSQELKIVN
+PHNQVKKVPGTQQELDKMGVKIKIEQFKSGAINKPVSIPNTYERLKQHPAGPEQITSSMV
+EGTIEAVDIMVFILVLGGLIGVVQASGSFESGLLALTKKTKGHEFMLIVFVSILMIIGGT
+LCGIEEEAVAFYPILVPIFIALGYDSIVSVGAIFLASSVGSTFSTINPFSVVIASNAAGT
+TFTDGLYWRIGACIVGAIFVISYLYWYCKKIKNDPKASYSYEDKDAFEQQWSVLKDDDSA
+HFTLRKKIILTLFVLPFPIMVWGVMTQGWWFPVMASAFLIFTIIIMFIAGTGKSGLGEKG
+TVDAFVNGASSLVGVSLIIGLARGINLVLNEGMISDTILHFSSSLVQHMSGPLFIIVLLF
+IFFCLGFIVPSSSGLAVLSMPIFAPLADTVGIPRFVIVTTYQFGQYAMLFLAPTGLVMAT
+LQMLNMRYSHWFRFVWPVVAFVLIFGGGVLITQVLIYS*
+>abc_00010
+MTHLTKVLDTLTGICVVLLFSKYFVAYANMVFDWNLRWYLLENIPHLPIILFILMFIFGV
+PSEMIKDRQRKNNGV*
+>abc_00011
+MRLQKAPLVTSGLVLGLLGLGNLLKDLSLTLNAVCGIFAFLIWIHLLCTMIKYFNNVKEQ
+LNSPLVSSVFTTFFMSGFLGTTYLNTFFSNITFINSLITPIWILCLVGIMTHMIIFSIKY
+LKDFSLENVYPSWTVLFIGIAIAGLTAPVSGCFFIGQLTVIYGFVATCIVLPIVFKRLKA
+FPLQTSIKPNTSTICAPFSLVAAAYVIAFPKANAFIVIIFLILAQIFYFYIIIQLPKLLK
+EPFSPVFSAFTFPLVISATALKNSLPVLMFPDIWKGLLFIEVLLATVIVLRVFIGYLHFF
+LKKENQDKFLRNASQ*
+>abc_00012
+MRNQIQKLLDSDLSSLHISKQTGVPQSTIHRMRKKERSLDNMSLKNAELLYKFANSIFSN
+EN*
+>abc_00014
+MEGLFNAIKDTVTAAINNDGAKLGTSIVSIVENGVGLLGKLFGF*
+>2_7
+MTGLAEAIANTVQAAQQHDSVKLGTSIVDIVANGVGLLGKLFGF*
+>abc_00016
+LGYKNILIDFDDTIVDFYDAEEWAFHYMANVFNHKATKDDFLTFKKINHQHWEAFQQNKL
+TKSEVLSERFVNYFKHHQMEVDGHRADVLFRNGLAEAKVKYFDQTLETIVELSKRHDLYI
+VTNGVTETQKRRLNQTPLHKYIKKIFISEETGYQKPNPEFFNYVFNDIGEDERQHSIIVG
+DSLTSDILGGINAGIATCWFNFRGFDHNPGIIPDYEINSWKQLNDIVR*
diff --git a/t/data/post_analysis/query_6.gff.proteome.faa b/t/data/post_analysis/query_6.gff.proteome.faa
new file mode 100644
index 0000000..ed8f1e7
--- /dev/null
+++ b/t/data/post_analysis/query_6.gff.proteome.faa
@@ -0,0 +1,19 @@
+>abc_00002
+MKLFFIVSLTIIWGDIFLGNEIIHLLTALTTTLGVVNSRKGIKNFRVAQ
+>3_3
+LTNLRGGSFLTILDFSLQEAQSLLTGAEDLKSAKYIFTETPTLKNGDIALLIEKDSLRTP
+RAFEVGAHDQGTNVTYLGPTRSQMGGEETTKNTARVFGGTHAGIEGGGFSQRTVETLAET
+PAVPVGDGLTDKDHPTLVLAHSLTAGEVLKKNYADIFFTSLADGRGDVANAIMQGAFIMA
+LTFHLGGPKELNPTDDLLNPRTNIAGENGGNILITDFIDPRAKGSGVIYTDIWVSIFEPA
+QAWKEGVELLKTYQVNLEMTHTTGNGDVIFENCLPSFHNAHTKIGGEIFEKNGIRDLEVT
+HAVFEGEASVVIQEADFRMPPTKAVGVATLGKF*
+>abc_00012
+MRNQNQKLLFSDFPSLHIWGQTGVQQSTIFRMSPNERSWGNMSLKNAELFYKFPNSIFRG
+EN*
+>abc_00014
+MEGLFFAITHTVTAGVNNDGTKLGTFIVTLAENGGGLLGKIFGFY
+>3_5
+LGGKNILKDFDDFIVDPYDAEGGAFHYKANVFFHKAPNDDFWGFKKINHQHWFAFHPNKL
+TRGEVLSERFVNFFKHPHMEVGGHRADELFRNFLADPNVKYWGQTLEKIVELFKRHPFYI
+VRGGVTEKQKRRFNQTPFHKYRGKIFIYEETGFQKPPPEFFRGVFNDNGEDEFQHSPIVG
+DWGTSDIQGGINFGIAPCWFNWGGFDHNPGIIFDYDPNSWKRGNDIVH*
diff --git a/t/data/post_analysis_expected/accessory.header.embl b/t/data/post_analysis_expected/accessory.header.embl
new file mode 100644
index 0000000..fa35444
--- /dev/null
+++ b/t/data/post_analysis_expected/accessory.header.embl
@@ -0,0 +1,7 @@
+ID Genome standard; DNA; PRO; 1234 BP.
+XX
+FH Key Location/Qualifiers
+FH
+XX
+SQ Sequence 1234 BP; 789 A; 1717 C; 1693 G; 691 T; 0 other;
+//
diff --git a/t/data/post_analysis_expected/accessory.tab b/t/data/post_analysis_expected/accessory.tab
new file mode 100644
index 0000000..e69de29
diff --git a/t/data/post_analysis_expected/core_accessory.header.embl b/t/data/post_analysis_expected/core_accessory.header.embl
new file mode 100644
index 0000000..a955257
--- /dev/null
+++ b/t/data/post_analysis_expected/core_accessory.header.embl
@@ -0,0 +1,55 @@
+ID Genome standard; DNA; PRO; 1234 BP.
+XX
+FH Key Location/Qualifiers
+FH
+FT misc_feature 11
+FT /label=group_12
+FT /locus_tag=group_12
+FT /colour=2
+FT misc_feature 10
+FT /label=group_13
+FT /locus_tag=group_13
+FT /colour=2
+FT misc_feature 2
+FT /label=group_5
+FT /locus_tag=group_5
+FT /colour=2
+FT feature 12
+FT /label=hly
+FT /locus_tag=hly
+FT /colour=2
+FT feature 8
+FT /label=speH
+FT /locus_tag=speH
+FT /colour=2
+FT misc_feature 3
+FT /label=group_8
+FT /locus_tag=group_8
+FT /colour=2
+FT misc_feature 9
+FT /label=group_2
+FT /locus_tag=group_2
+FT /colour=2
+FT misc_feature 7
+FT /label=group_3
+FT /locus_tag=group_3
+FT /colour=2
+FT feature 1
+FT /label=yfnB
+FT /locus_tag=yfnB
+FT /colour=2
+FT misc_feature 4
+FT /label=group_7
+FT /locus_tag=group_7
+FT /colour=2
+FT feature 6
+FT /label=argF
+FT /locus_tag=argF
+FT /colour=2
+FT feature 5
+FT /label=arcC1
+FT /locus_tag=arcC1
+FT /colour=2
+XX
+SQ Sequence 1234 BP; 789 A; 1717 C; 1693 G; 691 T; 0 other;
+//
diff --git a/t/data/post_analysis_expected/core_accessory.tab b/t/data/post_analysis_expected/core_accessory.tab
new file mode 100644
index 0000000..5c7f981
--- /dev/null
+++ b/t/data/post_analysis_expected/core_accessory.tab
@@ -0,0 +1,48 @@
+FT variation 11
+FT /colour=4
+FT /gene=group_12
+FT /taxa="query_6"
+FT variation 10
+FT /colour=4
+FT /gene=group_13
+FT /taxa="query_2"
+FT variation 2
+FT /colour=4
+FT /gene=group_5
+FT /taxa="query_1 query_2"
+FT variation 12
+FT /colour=4
+FT /gene=hly
+FT /taxa="query_1 query_2"
+FT variation 8
+FT /colour=4
+FT /gene=speH
+FT /taxa="query_1 query_2"
+FT variation 3
+FT /colour=4
+FT /gene=group_8
+FT /taxa="query_2"
+FT variation 9
+FT /colour=4
+FT /gene=group_2
+FT /taxa="query_2"
+FT variation 7
+FT /colour=4
+FT /gene=group_3
+FT /taxa="query_2"
+FT variation 1
+FT /colour=4
+FT /gene=yfnB
+FT /taxa="query_2"
+FT variation 4
+FT /colour=4
+FT /gene=group_7
+FT /taxa="query_2"
+FT variation 6
+FT /colour=4
+FT /gene=argF
+FT /taxa="query_1 query_2"
+FT variation 5
+FT /colour=4
+FT /gene=arcC1
+FT /taxa="query_2"
diff --git a/t/data/post_analysis_expected/gene_presence_absence.csv b/t/data/post_analysis_expected/gene_presence_absence.csv
new file mode 100644
index 0000000..f320ce2
--- /dev/null
+++ b/t/data/post_analysis_expected/gene_presence_absence.csv
@@ -0,0 +1,14 @@
+"Gene","Non-unique Gene name","Annotation","No. isolates","No. sequences","Avg sequences per isolate","Genome Fragment","Order within Fragment","Accessory Fragment","Accessory Order with Fragment","QC","query_1","query_2","query_6"
+"group_5","","Gonococcal growth inhibitor III","2","2","1","1","2",,,"","1_6","2_7",""
+"hly","","Alpha-toxin","2","2","1","1","12",,,"","1_1","2_1",""
+"speH","","hypothetical protein","2","2","1","1","8",,,"","1_2","2_2",""
+"argF","","Ornithine carbamoyltransferase","2","2","1","1","6",,,"","1_3","2_3",""
+"group_12","","hypothetical protein","1","2","2","1","11",,,"","","","abc_00002 abc_00002"
+"group_13","","hypothetical protein","1","2","2","1","10",,,"","","abc_00003 abc_00003",""
+"group_6","","","1","2","2","","","","","","","abc_01705 abc_01705",""
+"group_8","","C4-dicarboxylate transporter/malic acid transport protein","1","2","2","1","3",,,"","","abc_00011 abc_00011",""
+"group_2","","superantigen-like protein","1","2","2","1","9",,,"","","abc_00004 abc_00004",""
+"group_3","","superantigen-like protein","1","2","2","1","7",,,"","","abc_00006 abc_00006",""
+"yfnB","","Putative HAD-hydrolase yfnB","1","2","2","1","1",,,"","","abc_00016 abc_00016",""
+"group_7","","hypothetical protein","1","2","2","1","4",,,"","","abc_00010 abc_00010",""
+"arcC1","","Carbamate kinase 1","1","2","2","1","5",,,"","","abc_00008 abc_00008",""
diff --git a/t/data/prank_input.fa b/t/data/prank_input.fa
new file mode 100644
index 0000000..59c5769
--- /dev/null
+++ b/t/data/prank_input.fa
@@ -0,0 +1,59 @@
+>1234_8#75_04759
+ATGAGCGAGCAGTTAACGGACCAGGTCCTGGTTGAACGGGTCCAGAAGGGAGATCAGAAA
+GCCTTTAACTTACTGGTAGTGCGCTACCAGCATAAAGTGGCGAGTCTGGTTTCCCGCTAT
+GTGCCATCGGGCGACGTTCCCGATGTCGTACAGGAATCATTTATTAAGGCCTATCGCGCG
+CTGGATTCTTTCCGGCGGGATAGTGCTTTTTATACCTGGTTGTATCGTATTGCGGTCAAT
+ACCGCGAAGAACTACCTGGTTGCGCAGGGGCGTCGTCCGCCTTCCAGTGATGTAGACGCG
+ATTGAAGCAGAAAACTTTGAAAGCGGCGGCGCGCTGAAAGAAATTTCGAACCCTGAGAAC
+TTAATGTTGTCAGAAGAACTGAGACAGATAGTTTTCCGAACTATTGAGTCCCTCCCGGAA
+GATTTACGTATGGCAATCACCTTACGGGAGCTGGATGGCCTGAGCTATGAAGAGATAGCG
+GCTATCATGGATTGTCCGGTGGGGACGGTGCGTTCACGTATCTTCCGGGCGCGGGAAGCT
+ATTGATAATAAAGTTCAACCGCTTATCAGGCGTTGA
+>1111#5_04506
+ATGGCAATCACCTTACGGGAGCTGGATGGCCTGAGCTATGAAGAGATAGCGGCTATCATG
+GATTGTCCGGTGGGGACGGTGCGTTCACGTATCTTCCGGGCGCGGGAAGCTATTGATAAT
+AAAGTTCAACCGCTTATCAGGCGTTGA
+>Salmonella_enterica_subsp_enterica_serovar_Typhimurium_DT104_v1_02853
+ATGAGCGAGCAGTTAACGGACCAGGTCCTGGTTGAACGGGTCCAGAAGGGAGATCAGAAA
+GCCTTTAACTTACTGGTAGTGCGCTACCAGCATAAAGTGGCGAGTCTGGTTTCCCGCTAT
+GTGCCATCGGGCGACGTTCCCGATGTCGTACAGGAATCATTTATTAAGGCCTATCGCGCG
+CTGGATTCTTTCCGGGGGGATAGTGCTTTTTATACCTGGTTGTATCGTATTGCGGTCAAT
+ACCGCGAAGAACTACCTGGTTGCGCAGGGGCGTCGTCCGCCTTCCAGTGATGTAGACGCG
+ATTGAAGCAGAAAACTTTGAAAGCGGCGGCGCGCTGAAAGAAATTTCGAACCCTGAGAAC
+TTAATGTTTTCAGAAGAACTGAGACAGATAGTTTTCCGAACTATTGAGTCCCTCCCGGAA
+GATTTACGTATGGCAATCACCTTACGGGAGCTGGATGGCCTGAGCTATGAAGAGATAGCG
+GCTATCATGGATTGTCCGGTGGGGACGGTGCGTTCACGTATCTTCCGGGCGCGGGAAGCT
+ATTGATAATAAAGTTCAACCGCTTATCAGGCGTTGA
+>Salmonella_enterica_subsp_enterica_serovar_Typhimurium_SL1344_v2_02736
+ATGAGCGAGCAGTTAACGGACCAGGTCCTGGTTGAACGGGTCCAGAAGGGAGATCAGAAA
+GCCTTTAACTTACTGGTAGTGCGCTACCAGCATAAAGTGGCGAGTCTGGTTTCCCGCTAT
+GTGCCATCGGGCGACGTTCCCGATGTCGTACAGGAATCATTTATTAAGGCCTATCGCGCG
+CTGGATTCTTTCCGGGGGGATAGTGCTTTTTATACCTGGTTGTATCGTATTGCGGTCAAT
+ACCGCGAAGAACTACCTGGTTGCGCAGGGGCGTCGTCCGCCTTCCAGTGATGTAGACGCG
+ATTGAAGCAGAAAACTTTGAAAGCGGCGGCGCGCTGAAAGAAATTTCGAACCCTGAGAAC
+TTAATGTTGTCAGAAGAACTGAGACAGATAGTTTTCCGAACTATTGAGTCCCTCCCGGAA
+GATTTACGTATGGCAATCACCTTACGGGAGCTGGATGGCCTGAGCTGTGAAGAGATAGCG
+GCTATCATGGATTGTCCGGTGGGGACGGTGCGTTCACGTATCTTCCGGGCGCGGGAAGCT
+ATTGATAATAAAGTTCAACCGCTTATCAGGCGTTGA
+>Salmonella_enterica_subsp_enterica_serovar_Typhimurium_str_D23580_v1_02783
+ATGAGCGAGCAGTTAACGGACCAGGTCCTGGTTGAACGGGTCCAGAAGGGAGATCAGAAA
+GCCTTTAACTTACTGGTAGTGCGCTACCAGCATAAAGTGGCGAGTCTGGTTTCCCGCTAT
+GTGCCATCGGGCGACGTTCCCGATGTCGTACAGGAATCATTTATTAAGGCCTATCGCGCG
+CTGGATTCTTTCCGGGGGGATAGTGCTTTTTATACCTGGTTGTATCGTATTGCGGTCAAT
+ACCGCGAAGAACTACCTGGTTGCGCAGGGGCGTCGTCCGCCTTCCAGTGATGTAGACGCG
+ATTGAAGCAGAAAACTTTGAAAGCGGCGGCGCGCTGAAAGAAATTTCGAACCCTGAGAAC
+TTAATGTTGTCAGAAGAACTGAGACAGATAGTTTTCCGAACTATTGAGTCCCTCCCGGAA
+GATTTACGTATGGCAATCACCTTACGGGAGCTGGATGGCCTGAGCTATGAAGAGATAGCG
+GCTATCATGGATTGTCCGGTGGGGACGGTGCGTTCACGTATCTTCCGGGCGCGGGAAGCT
+ATTGATAATAAAGTTCAACCGCTTATCAGGCGTTGA
+>Salmonella_enterica_subsp_enterica_serovar_Typhimurium_str_DT2_v1_02741
+ATGAGCGAGCAGTTAACGGACGTCCTGGTTGAACGGGTCCAGAAGGGAGATCAGAAA
+GCCTTTAACTTACTGGTAGTGCGCTACCAGCATAAAGTGGCGAGTCTGGTTTCCCGCTAT
+GTGCCATCGGGCGACGTTCCCGATGTCGTACAGGAATCATTTATTAAGGCCTATCGCGCG
+CTGGATTCTTTCCGGGGGGATAGTGCTTTTTATACCTGGTTGTATCGTATTGCGGTCAAT
+ACCGCGAAGAACTACCTGGTTGCGCAGGGGCGTCGTCCGCCTTCCAGTGATGTAGACGCG
+ATTGAAGCAGAAAACTTTGAAAGCGGCGGCGCGCTGAAAGAAATTTCGAACCCTGAGAAC
+TTAATGTTGTCAGAAGAACTGAGACAGATAGTTTTCCGAACTATTGAGTCCCTCCCGGAA
+GATTTACGTATGGCAATCACCTTACGGGAGCTGGATGGCCTGAGCTATGAAGAGATAGCG
+GCTATCATGGATTGTCCGGTGGGGACGGTGCGTTCACGTATCTTCCGGGCGCGGGAAGCT
+ATTGATAATAAAGTTCAACCGCTTATCAGGCGTTGA
diff --git a/t/data/proteome_with_and_without_descriptions.faa b/t/data/proteome_with_and_without_descriptions.faa
new file mode 100644
index 0000000..d2547e9
--- /dev/null
+++ b/t/data/proteome_with_and_without_descriptions.faa
@@ -0,0 +1,29 @@
+>1234#10_00001
+MSKHGFFQITQKLFLRKGDELLILRDRKSGLGDLPGGRMNENEFFEDWSLSMQREIEEEL
+GSQVQIRVSTKPLFIHKHKVNEGNFPCIIIAYHADYLGGDIILSDEHDYISWEKVQTYEP
+SPLFTEYMLDAVNLYLKEYAPLVH*
+>1234#10_00002
+MIIKLKIILNSYLIYYFLRGQNTLIRTLLFEFPLTTFFVFLMVATFFIVNVFLPEHLIRQ
+YFLNHPGQIQPLSWIGAVFYHGNLIHLFGNMFYLFFLGRAVEYKAGKGRWLLFFFMAALI
+SSLLDSFIRGVILHDPTPVVGASGAISGIAAVAALLSPFSLRFNQRNIPFPVFLVAWIMV
+YSDITNVFTEDGVARWAHLGGFISVIFAAYFLKPTERKQLHSGFILNLIFIILTLILAFF
+YSNRS*
+>1234#10_00003
+VKTTLSGEIEKLRYEVAVKIVNLQGEVLDLRAEMKINFSEVNSKILKLQFEFEMAKIRKE
+LKTEIADLRAETKTDFLELQKSIVDIYKTISTQTRWILGVATLFAAIGKVIN*
+>1234#10_00005 imidazoleglycerol-phosphate dehydratase or histidinol-phosphatase
+LTDKLIGFYDPVRMKAERKTSETEIKLEMNLRGTGQYQFDTEIPFFEHMLSHISKHGLID
+LNLWLRGDIEIDCHHSVEDTAILMGATIHKQLGDKAGIFRYGHFTLTMDEVLTTVAVDLG
+GRYFFKYTGPELTGKFGIYDAELSLEFLQKLALNAKMNLHVVVHYGDNKHHVHESIFKAL
+GKALRMAIAQDSAAAGAIPSTKGVLE*
+>1234#10_00006
+MIAILDYGMGNIHSCLKAVSLYTKDFVFTKDHSTIENSKALILPGDGHFDKAMENLNSTG
+LRKTIDKHVTSGKPLFGICIGFQILFESSEEIAQGSKKEQIEGLGYIKGKIKKFHGKDFK
+VPHIGWNRLQIRRKDKSVLLKGIGDQSFFYFIHSYRPTDAEGNAITGLCDYYQEKFPAVV
+EKNNIFGTQFHPEKSHTHGLKLLENFIRFI*
+>1234#10_00007 imidazole glycerol phosphate synthase subunit HisH
+MIVIPAIDLFDNCAVRLFKGNYEEKKIYSSEPWKLAESFAKNGATLLHLVDLNGARNQLG
+VNEDSILKIRETTSLKVQLGGGIRDKEKLAYYDKIGINRFILGTAAVTNPDLLKYALDNY
+GKERVVVAVDARDGIVKIAGWEKDSGIHYRDLLERLVKAGIEHIVFTDIAQDGTLAGPNL
+EAYREILNSYPFQVIASGGIASLKDLMDLSSLKTKISLYGVITGKALYEGKLDLAKAISS
+I*
\ No newline at end of file
diff --git a/t/data/query_1.fa b/t/data/query_1.fa
new file mode 100644
index 0000000..0b8bacd
--- /dev/null
+++ b/t/data/query_1.fa
@@ -0,0 +1,8 @@
+>1_1
+AAA
+>1_2
+BBB
+>1_3
+CCC
+>1_6
+FFF
\ No newline at end of file
diff --git a/t/data/query_1.gff b/t/data/query_1.gff
new file mode 100644
index 0000000..a45c73e
--- /dev/null
+++ b/t/data/query_1.gff
@@ -0,0 +1,271 @@
+##gff-version 3
+##sequence-region abc|SC|contig000001 1 15000
+abc|SC|contig000001 Prodigal:2.60 CDS 172 1131 . - 0 ID=1_1;gene=different;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:Q2G1X0,protein motif:TIGRFAMs:TIGR01002,protein motif:Pfam:PF07968.6;locus_tag=abc_00001;product=Alpha-toxin,beta-channel forming cytolysin,Leukocidin/Hemolysin toxin family protein;protein_id=gnl|SC|abc_00001
+abc|SC|contig000001 Prodigal:2.60 CDS 1804 1950 . + 0 ID=abc_00002;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00002;product=hypothetical protein;protein_id=gnl|SC|abc_00002
+abc|SC|contig000001 Prodigal:2.60 CDS 1934 2131 . + 0 ID=abc_00003;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00003;product=hypothetical protein;protein_id=gnl|SC|abc_00003
+abc|SC|contig000001 Prodigal:2.60 CDS 2621 3337 . - 0 ID=abc_00004;inference=ab initio prediction:Prodigal:2.60,protein motif:CLUSTERS:PRK13350,protein motif:Pfam:PF02876.11;locus_tag=abc_00004;product=superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00004
+abc|SC|contig000001 Prodigal:2.60 CDS 3445 4170 . - 0 ID=1_2;gene=speH;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P0C0I6,protein motif:CLUSTERS:PRK13349,protein motif:Pfam:PF02876.11;locus_tag=abc_00005;note=SPE H;product=hypothetical protein,superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00005
+abc|SC|contig000001 Prodigal:2.60 CDS 4265 4990 . - 0 ID=abc_00006;inference=ab initio prediction:Prodigal:2.60,protein motif:CLUSTERS:PRK13043,protein motif:Pfam:PF02876.11;locus_tag=abc_00006;product=superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00006
+abc|SC|contig000001 Prodigal:2.60 CDS 5428 6429 . + 0 ID=1_3;eC_number=2.1.3.3;gene=argF;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P99073,protein motif:CLUSTERS:PRK04284,protein motif:Cdd:COG0078,protein motif:TIGRFAMs:TIGR00658,protein motif:Pfam:PF00185.1;locus_tag=abc_00007;product=Ornithine carbamoyltransferase,ornithine carbamoyltransferase,Ornithine carbamoyltransferase,ornithine carbamoyltransferase,Aspartate/ornithine carbamoyltransferase%2C As [...]
+abc|SC|contig000001 Prodigal:2.60 CDS 6449 7384 . + 0 ID=abc_00008;eC_number=2.7.2.2;gene=arcC1;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:Q7A627,protein motif:CLUSTERS:PRK12353,protein motif:TIGRFAMs:TIGR00746,protein motif:Pfam:PF00696.22;locus_tag=abc_00008;product=Carbamate kinase 1,putative amino acid kinase,carbamate kinase,Amino acid kinase family protein;protein_id=gnl|SC|abc_00008
+abc|SC|contig000001 RNAmmer:1.2 rRNA 7556 9112 . + 0 ID=abc_01705;inference=COORDINATES:profile:RNAmmer:1.2;locus_tag=abc_01705;product=16S ribosomal RNA
+abc|SC|contig000001 Prodigal:2.60 CDS 9419 9646 . + 0 ID=abc_00010;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00010;product=hypothetical protein;protein_id=gnl|SC|abc_00010
+abc|SC|contig000001 Prodigal:2.60 CDS 9952 10899 . - 0 ID=abc_00011;inference=ab initio prediction:Prodigal:2.60,protein motif:Pfam:PF03595.11;locus_tag=abc_00011;product=C4-dicarboxylate transporter/malic acid transport protein;protein_id=gnl|SC|abc_00011
+abc|SC|contig000001 Prodigal:2.60 CDS 11148 11336 . + 0 ID=abc_00012;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00012;product=hypothetical protein;protein_id=gnl|SC|abc_00012
+abc|SC|contig000001 Aragorn:1.2.34 tRNA 11803 11878 . - 0 ID=abc_00013;inference=COORDINATES:profile:Aragorn:1.2.34;locus_tag=abc_00013;product=tRNA-Arg(tct)
+abc|SC|contig000001 Prodigal:2.60 CDS 12241 12375 . + 0 ID=abc_00014;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P11699,protein motif:Pfam:PF05480.5;locus_tag=abc_00014;product=Gonococcal growth inhibitor III,Staphylococcus haemolytic protein;protein_id=gnl|SC|abc_00014
+abc|SC|contig000001 Prodigal:2.60 CDS 12432 12566 . + 0 ID=1_6;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P11699,protein motif:Pfam:PF05480.5;locus_tag=abc_00015;product=Gonococcal growth inhibitor III,Staphylococcus haemolytic protein;protein_id=gnl|SC|abc_00015
+abc|SC|contig000001 Prodigal:2.60 CDS 12699 13385 . + 0 ID=abc_00016;eC_number=3.-.-.-;gene=yfnB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:O06480,protein motif:CLUSTERS:PRK09449,protein motif:TIGRFAMs:TIGR02254,protein motif:Pfam:PF00702.1;locus_tag=abc_00016;product=Putative HAD-hydrolase yfnB,dUMP phosphatase,HAD hydrolase,haloacid dehalogenase-like hydrolase;protein_id=gnl|SC|abc_00016
+##FASTA
+>abc|SC|contig000001
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
+ATACCCACCACATTTGGTGGAGAACCAAAAATTAGCCGAAAAACATCATTTCTGAAGTTA
+TCGGCTAAAGTTATAAATTATATTTATTTGTACATGAACAAATAATTTACATTAATTTGT
+CATTTCTTCTTTTTCCCAATCGATTTTATATCTTTCTGAAGAACGATCTGTCCATTTATC
+TTTAGTATTGGTACCTTTCCAATTTGTTGAAGTCCAATGCAATTGGTAGTCATCACGAAC
+TCGTTCGTATATTACATCTATATTTGTTTGTTGTTTGGATGCTTTTCTATCCATAGTAAT
+AACTGTAGCGAAGTCTGGTGAAAACCCTGAAGATAATAGAGAACTTGCTTTGTTAGGATC
+AAGGAAGTTCTCTGCTGCTTTCATAGAACCATTTCTAGTTTTCATGAAAAGTTGATTGCC
+ATATACCGGGTTCCAAGAATCTCTATCATATGGTCCCCAATTTTGATTCACCATATTGTT
+AAATATCACTTTCCAGCCTACTTTTTTATCAGTTGGGCTCTCTAAAATTGTTTTGAAATC
+AGGTTGAACATATTTCAGTGTATGACCAATCGAAACATTTGCACCAATAAGGCCGCCAAT
+TTTTCCTGTATCATCACCAGTAACATTACCGTTGAATCCATAAGTTAAAGTACTCATATA
+CTCTTTTGTATCAATCGAATTTCTTGGATAGTAATCAGATATTTGAGCTACTTCATTATC
+AGGTAGTTGCAACTGTACCTTAAAGGCTGAAGGCCAGGCTAAACCACTTTTGTTAGCACC
+TTCTTCGCTATAAACTCTATATTGACCAGCAATGGTACCTTTCGTTCTAATAACTAGCAG
+TTTTTTATTGTGATTTTTATCATCGATAAAACTATAAAATACTTTTTTGTGCATGCCATT
+TTCTTTATCATAAGTGACTAAATCACCTGTTTTTACTGTAGTATTGCTTCCAATATCTGT
+AGTACCGGTTTTAATATTAATATCAGAATCTGCGGCATTAGCGACAGGATTCATTAATAT
+GGAACCTAGCAATAGTGTTGTTGTTACTGAGCTGACTATACGTGTTTTCATTTTCATCAT
+CCTTCTATTTTTTTTAACGATTTGAGGAAACAATAATCAATATGTCAATTTAGAATATTG
+CAGTTGAGACATATCAAATATTTATAATCGTTTATATTAGTATATTTAATGTAGCAACTG
+ATAAATTACTGAGTGATGATGAGTGATTATTTTAAGAATATGTTTTTAACTTTTATTTAA
+AATTTGAAAGGAAGCATTTCAATTTCGAGGGTTAGTCAAAGTTGAATAAATTCTTTATGA
+AACAAGGAAAAGACATAGCTAATTTTATTGATTAATTTCTTTAAAACTAATGATTTGTTT
+GATTTAAAAATGTAATCGATTACAATATAAAAATACAAATATCTTAGAATTAAATCAATT
+AATTAACTATTAAATAAAAATTAAATATATATTAACTACTGTAAATTAATAAATAGAAAT
+AGAGAAAAAGGGTATTAATTATGTTTGGAATTTCGTCGGGAATAATTTTTGCCATTACAT
+AGAAATATCTAATAGATAATGAAAAAGTATCGTATGTATTTTTAATATAGTGTAAAATAT
+CATATGTAAAATAAAATGTAGATTTTTAGTTAGAGGCATTATAAGAAAATTTTGAGTATA
+GGTTAGCTTTTAATTATGAATCTTATTGAAATTTGATTAATAAATATATGATAGGGGATT
+AAAATGAAACTATTTTATATCGTATTTCTTATTATTATATGGCTGAATATATTTTTAGGA
+AATGAAATTATCCATACACTGACTGTTTTAATAACAACATTGTATATTGTTAATTCAAGA
+AAGGGGATTAAAAATGACAGAGTTGAATAATATTATAAACTCTCTTCAATCTTTGTTTGA
+GTCTGAATCAGGCTATAAAATTTCGAAAAATTCAGGAGTTCCATATCAAACAGTACAAGA
+TTTAAGAAATGGGAAAACCAAACTAGAAGATGCTAGATTTAGAACGATTATTAAACTTTA
+TAGTTACTATGTCTCATTAAAAGAACATTAATCATGGGACAATAAAGTATTGCTATAATA
+ATTGAATCATTAAATGAAGGAATAGAGCCTAAGACATAATAAATCAATGTCTTAGGCTCT
+ACAATATTATATTGGTAGTAGTTGACCGAATGAAAATGACCATGTAACAAGCATTTTTGG
+GGCCCCAACACAGAAGCTGACGAAAAGTCAGCTTACAATAATGTGCAAGTTGGGGATGGG
+CCCCAACACAGAGAATTTCAAAAAGAAATTCTACAGACAATGCAAGTTGGCGGGGCCCCA
+ACATAGAGAAATTCAAAAAGAAATTCTACAGACAATGCAAGTTGGGGAGTGACAACGAAA
+TAAATTTTATAAAATACCATTTCTGTCACATTCCTACTCCCAATTCCATTTAAATATATA
+GAAAATTTCACCTATTATATACATCATACACTTTAAAAATTATCATTTAAATAATCTGAT
+TTGGAATTAAAGTGCATGAAGTATAAGTCACCTTCATATACTAATCAAAGAGGACGTCAA
+CAGTTATTTTATTAGGATTTTTAACATAAACATTTGCTAGATCTGAATGTAATCTTTTGC
+TTAAATCAATAGTGTAGTTATTACCGCCACCGGTGATCTTAAGCTTACCTTTATTACGAT
+TTTCGGTATATAATATTTTATTTTTTATTAACGCTTCTCGTGCACGGAAATCGATTTCTT
+TCAATGTTAATACTGGTTTATTGCCTTGGTATATTTTATGCGCACCAATAATCGTTTGTA
+GTTTATCTTTGTATTGCACAAAAAGATTATAAGTTTTATCAGAAGGTTTTGCGGCTGGTG
+TAACGCCACCTGTAAATGTCTCTCTATAAGACCACCATAACTGATCAGTATCTTTGTCTT
+TTAGTCCAAACACATCTACGTAACGATCTTTTAACTGATTAATATTTCCCCAACTTTCAG
+CGCCCCATAAAGATATATGTGCTGACCATGAATATCTCTTAAGTTCAACATAAATGTTTC
+CATTATCATATTGATATAGCCATTTATTTGAAAATGAAAAATGAGGCTGTGTGTAATATT
+TAATTAATTCATTGATGTTAGTTTCATCTTGACCAATGCTATAAGCTTTAGCTTCAGAGT
+AAAAACTAAATACTGGTTTTTGATTTTGAGGTAATACAGTACCTAATAGTAATAATGTTG
+TCGTTAAAATTATATTTTTCGTGATGTTCTTACTCATTAGAACATCTCCTTTCAGAGGAA
+TCATGATACGAGGAATAAGAAATTTAAATGTGAGCGAAGTCAATATAGTATTTGCGATTA
+TTTTTATTAACTCCATTATTATTGTTAGTTTGATTTTTCGAGGATAACTTCAATTTTTGC
+ATTTTGAGGTTTTTTAACATATCTATTTGCATCAGTTGATGGCAACCTTTTACTTAAATC
+TATTGTGTAGTTATTGTCTGTACCTGTTATTTTAATTTGTCCTTTATTATAAGAATTATT
+ATATAATTTTTTACTTTTAATTAATGTTTGACGAATACGAAAATCTAATTCTTTTAAAGT
+TAAAACAGGCTTATTGCCTTCATAAACTGGAAATCCGCCAGTAAACGTTTCTGCTTTATC
+TTTATATGTTACATTCAGTTTATAGTGTTTATCGTTAGATGTTGCTGCAGGAGTAACACC
+ACCAGTAAACGTTTCTTGAGATAATGCAAAAGAATCAATGGTTTCTTGGTCTTTTATGCC
+AAAAATATCAACGCTTTTATTTCTTAATTGGTTGATATTGCCCCAACTTTCAGGTCCATA
+AACTTGAATATGACTATACCAAGAAAACTGTAACAACGTTGCATGAATCGTACCGTTATC
+TTTTTGCCATAACGTACTGTTAGAGAAGGTTAAATATTTTTGCGAGTAATATTTAGTTAA
+CTCATTAACGTTAGTTTCGTTTTGATTTATATAATAAGCTTTCGCTTCAGATGAAGAATT
+GATAGGTGTATTAGGAAATTGTGTAAATGCTGTACCTAATAGTAACAATGTTGTTGATAA
+AATAATTTTTTTCGTGATGTTATTGTTCATTCGAATTTCTCCTTTGAGTATTGTTGGAAT
+GTTTAATTATAAAAAGGGGTTAATTAGATAATTGAAATTATCCGCATTTACAAAAGGTAA
+TAGGTTAGTTAGATTTTTCGAGTATGACTTCAATTTGTGCATTTTTAGGATTTTTAACAT
+AACGGTTTGTGTCAGTTAATTTTAACTTTTTACTTAAATCAATCGTGTAATTATTTCCAT
+CAGCAGTTATCTTAATTTGACCTTTATTAAATTCTCCGTTATATAACTTTTTATTCTTTA
+TTAATGTTTGACGAATACGGAAATCTAATTCTTTTAAAGTTAATACTGGTTTATTTCCTT
+TGTAAAATTCATGTCCACCGATGATAGTTTGTTGTTTATCACTATATTTTAAAAATAGTC
+TATAAGGTTTATCAGATGAAGTAGCTGCTGGCGTAACACCACCAGTAAATGTTTCATCAT
+AAGTCCAGTAACCTTCAACTGTGTCCTCATCTTTAGTTCCAAATATATCAACGTATTTAT
+TTCTTAACTGATTAATGTTTCCCCAACTCTCGGATCCAAACACTTGAATATGACTATACC
+AAACCCACGTTTGCAATGTTGCATGAATGCTACCATTGGGCTTTTGCCATAGCCATTTTC
+CAGATAATGAAAAATGCGGCTGAGTGTAATATTTGATTAACTCATTGATATTAGTCTCGT
+TTTCACTGATATTATAGGCTTTTGCTTCAGATGAAAAACTGATTGGTGTTTTAGGAAGTT
+GTGTTGATGTGGTTCCTAAAAGTAACAATGCTGTTGATAAAACTAATTTATTCATGATGT
+TCTTTTTCATATGAAAATCTCCTTTGCGTGAATTACCCAAAGTATATAAGCTATTACACC
+GATTCGGAATTAAATAAAAGCTAAAACTATGTTAAATAAACTTAAACAGTTAGTAGTGTT
+ATTTAAGCAAAACTTATCATTTTTAAGTTTTGGACAGAAACAGTACTTAATAAAGTAGGC
+GGGAGTTATATATTAAAAACGACACGTTACAATTATTCTCTAATCAATTGCATTAAATTG
+TTTGATAATTGAATTTTCTAACTACTTGAAAAATAGTTATACTTTAAATGTAGTACTTAT
+TTTAATTATTTCCTACTACTTAAATTTAATATTAATAAAATGTTCATTTAATTATTGATA
+AAATATTACAAATTTTAATAGTAGGTTGTGTTTATTTTGTATGCGCTTACAATTTAGGTG
+TAACTAAAATAAAAGGAGTTGTTATTAATGAAAAATTTACGAAACAGAAGTTTTTTAACT
+TTATTAGACTTTTCACGACAAGAGGTAGAATTCTTATTAACACTCTCCGAGGATTTAAAA
+CGTGCTAAATATATTGGCACTGAAAAGCCTATGTTAAAAAATAAAAATATTGCACTGTTA
+TTTGAAAAAGATTCTACAAGAACGCGATGTGCATTTGAAGTTGCAGCGCATGATCAAGGT
+GCAAATGTAACTTATTTAGGCCCAACTGGATCACAAATGGGTAAAAAAGAAACAACTAAA
+GATACTGCACGTGTGCTTGGTGGAATGTATGATGGCATTGAATACCGTGGTTTTTCACAA
+AGAACAGTAGAAACTTTAGCTGAAAATTCAGGCGTACCAGTGTGGAATGGTTTAACTGAT
+GAAGATCATCCTACTCAAGTTCTTGCTGATTTCTTAACAGCAAAAGAAGTCTTAAAAAAA
+GATTATGCAGATATTAACTTTACATATGTTGGAGATGGTCGTAATAACGTTGCAAATGCA
+TTAATGCAAGGTGCTGCCATTATGGGTATGAACTTCCATTTAGTTTGTCCAAAAGAATTA
+AATCCAACAGATGAATTATTAAATCGCTGTAAAAATATTGCCGCTGAAAATGGTGGCAAC
+ATATTAATCACAGATGATATTGACCAAGGTGTAAAAGGTTCGGATGTAATTTACACTGAT
+GTTTGGGTATCAATGGGTGAACCTGATGAAGTATGGAAAGAACGACTTGAATTATTGAAA
+CCATATCAAGTAAATAAAGAAATGATGGATAAAACTGGTAATCCAAATGTTATTTTTGAG
+CATTGCTTACCATCTTTCCATAATGCTGATACGAAAATTGGTCAACAAATTTTTGAAAAA
+TATGGTATTCGAGAAATGGAAGTTACAGATGAAGTATTCGAAAGTAAAGCTTCAGTTGTA
+TTCCAAGAAGCTGAGAACAGAATGCATACAATCAAAGCAGTCATGGTTGCTACATTGGGT
+GAATTTTAAATGATATAAGGAAGTGAATATGATGGCGAAAATAGTAGTAGCATTAGGTGG
+TAATGCTTTAGGAAAATCACCTCAAGAACAACTCGAGCTTGTTAAAAATACTGCGAAATC
+ATTAGTAGGATTAATAACAAAAGGACATGAGATTGTTATTAGTCATGGTAATGGACCACA
+GGTTGGAAGCATTAATTTGGGACTTAACTATGCTGCAGAACATAACCAAGGTCCGGCATT
+TCCATTTGCTGAATGTGGCGCAATGAGTCAAGCTTACATCGGCTATCAATTACAAGAAAG
+CTTACAAAATGAATTGCATTCTATTGGAATGGATAAACAAGTGGTAACACTAGTGACACA
+AGTTGAAGTTGATGAAAATGATCCGGCATTTAACAATCCTTCAAAACCAATTGGGTTATT
+TTACAACAAAGAAGAAGCTGAACAAATTCAAAAAGAAAAAGGATTTATATTTGTTGAAGA
+TGCTGGAAGAGGATATAGACGCGTTGTTCCTTCACCACAACCCATCTCTATTATTGAATT
+AGAGAGTATTAAAACACTTATTAAAAATGATACACTCGTTATTGCTGCTGGTGGTGGAGG
+TATACCAGTAATTAGAGAGCAACATGATGGTTTTAAAGGTATTGATGCAGTTATAGACAA
+AGATAAAACAAGTGCGTTGTTGGGTGCTAATATTCAATGCGATCAATTGATTATTTTAAC
+AGCAATTGATTATGTATATATTAATTTTAACACTGAAAACCAACAGCCTTTGAAAACAAC
+AAATGTTGATGAATTAAAACGATATATAGACGAAAATCAATTTGCAAAAGGAAGTATGTT
+ACCAAAAATTGAAGCAGCCATATCATTTATTGAAAACAATCCAAAAGGAAGTGTGCTTAT
+AACATCATTAAATGAATTAGATGCTGCCTTAGAGGGTAAAGTAGGTACTGTGATTAAAAA
+GTAATTGAATTGAAACGCTTTTCAATTACTATATGTCAAATGCATGATTTTTATTATTTA
+TGTGCACCCCCTGAAAATAATGCCTCTATTTTGATGCGGGGTGCACTTTCTTAATTTATA
+TTTATAAAATCTTTAAGGTAGAAATGCTAGGTTAAATGTCGAAGGAGATGAAACCGTGGA
+AAATACAATTAATGAAAGTGAAAAGAAAAAACGATTTAAATTAAAAATGCCAGGTGCATT
+TATGATTTTATTCATTTTAACGGTTGTTGCAGTTATAGCAACATGGGTTATTCCTGCTGG
+TGCATATTCTAAACTTTCTTACGAACCTTCATCCCAAGAACTAAAGATAGTTAACCCTCA
+TAACCAAGTGAAAAAGGTTCCGGGTACGCAACAGGAACTAGACAAAATGGGGGTTAAAAT
+TAAGATTGAACAATTTAAATCAGGTGCAATTAATAAGCCAGTATCAATTCCGAATACTTA
+TGAAAGATTAAAGCAACATCCAGCTGGACCAGAACAAATAACAAGTAGCATGGTTGAAGG
+TACGATAGAAGCGGTCGATATCATGGTATTCATTCTTGTACTAGGGGGACTTATTGGCGT
+AGTTCAAGCCAGTGGTTCTTTTGAATCGGGATTGTTAGCTTTAACGAAGAAAACAAAAGG
+GCATGAATTTATGCTAATTGTGTTTGTATCAATACTAATGATTATCGGCGGGACGTTATG
+TGGTATTGAAGAAGAAGCTGTAGCATTCTATCCGATTTTAGTCCCTATATTTATAGCGTT
+AGGATACGATTCTATCGTTTCAGTTGGTGCCATATTCCTTGCCAGCTCTGTCGGTAGTAC
+ATTTTCAACTATTAACCCGTTCTCGGTTGTAATTGCCTCTAATGCCGCTGGTACAACTTT
+TACGGATGGCTTGTATTGGAGAATAGGTGCTTGTATTGTCGGTGCGATTTTTGTTATTAG
+TTATTTATATTGGTACTGTAAAAAAATTAAAAACGATCCTAAAGCGTCATATTCTTATGA
+AGACAAAGATGCTTTTGAACAGCAATGGTCTGTATTAAAAGATGACGATAGTGCCCATTT
+TACTTTGCGTAAGAAGATAATCCTTACATTATTTGTACTACCATTTCCAATTATGGTATG
+GGGAGTTATGACGCAAGGTTGGTGGTTCCCAGTTATGGCTTCAGCATTTTTAATATTTAC
+AATTATAATAATGTTTATTGCTGGGACAGGTAAATCTGGATTGGGAGAAAAAGGAACTGT
+AGATGCATTTGTCAATGGTGCATCAAGTTTAGTAGGTGTATCTTTAATTATTGGTTTAGC
+TCGAGGTATTAATTTAGTGTTGAATGAAGGTATGATTTCAGATACAATCTTACACTTTTC
+ATCATCTTTAGTTCAACATATGAGTGGACCATTATTTATCATCGTATTACTATTTATTTT
+CTTCTGTTTAGGTTTTATCGTGCCATCATCTTCTGGATTAGCGGTATTATCAATGCCTAT
+CTTTGCACCACTAGCTGATACAGTAGGTATACCAAGATTCGTCATCGTTACGACATATCA
+ATTTGGTCAATATGCGATGTTATTCTTAGCGCCGACTGGACTTGTTATGGCCACACTACA
+AATGTTAAACATGCGATATTCACATTGGTTCCGATTTGTATGGCCGGTAGTTGCTTTTGT
+ATTGATTTTCGGTGGCGGAGTACTAATTACGCAAGTACTAATTTATTCATAATTTGAAAT
+GCTATATTATAAAAATACTAATTGGGTTTTATGCATCTCGTAGGTTTGTAGAAATACTAA
+ACTAAGCGAGGTGCATTATTATTTTTGATTAAGAAAATAATGACGGTAATGATAACACTA
+GTAAGTAATTGATACAATGCTCTATTTAATAATGATATTTTTAAAATTTGTTTTTAATGT
+AATGTTAGATCTATGGTATATTATATTTATCGTGGTAAATATGTATTTGCTGTAAACAGT
+TTTTGTAACACATGACACATATGGTTGTGAAAATAGCATATATAAAGGATGGCTATAAAT
+GACACATTTGACAAAGGTTTTAGATACACTAACTGGAATATGCGTAGTATTATTATTTAG
+TAAATATTTTGTGGCGTATGCAAATATGGTGTTTGATTGGAATTTAAGATGGTATTTGCT
+AGAAAACATACCACATTTGCCAATTATATTATTTATTCTGATGTTTATTTTCGGAGTACC
+TTCTGAAATGATAAAAGATAGGCAAAGGAAAAATAACGGTGTTTAATTTATCGATATTTA
+GAGGTGATAAAATTTGTCAACTATTACAAAGACTAAAATAAAAATCTTTATTAATTATTT
+TATTGGTATATTAGCCTTGGCGTTTGCTGCTTATATATTATTTAAATAAAGGTTAGAGTG
+AAACGTGTTTATGAACTAGACGTTCTAGTATAGTTACTACAGCTTTAGTCAGAAGGTATC
+ATTGATAAGATCATATTAAATCAAAGAGGCATTGATATACACTAAAAAGAGGCAAGATTA
+CCTGCCTCTTTTTTAGTTATTAAATATGCGTGTTAATTCTTGGTAATAGTGTTACTGAGA
+CGCATTACGAAGAAATTTATCTTGATTTTCCTTTTTTAAAAAGAAGTGAAGATATCCTAT
+AAAGACTCTAAGTACTATTACAGTGGCTAATAACACTTCGATAAACAAAAGACCTTTCCA
+AATATCTGGAAACATAAGTACAGGCAAACTGTTCTTTAAAGCAGTTGCTGAGATTACTAA
+AGGGAATGTGAAAGCTGAAAATACGGGCGAAAAAGGTTCTTTTAGTAATTTAGGCAATTG
+TATAATGATATAAAAATAAAATATTTGAGCTAATATTAAAAATATAATTACGATAAAAGC
+ATTCGCCTTAGGAAAGGCTATAACATATGCTGCAGCGACTAAAGAAAATGGTGCACAAAT
+TGTCGATGTGTTCGGTTTGATTGACGTCTGCAATGGAAATGCTTTTAATCGCTTGAAAAC
+AATAGGTAAGACAATACAAGTAGCTACAAAGCCATATATTACTGTTAATTGACCTATGAA
+AAAACATCCGCTAACGGGTGCCGTCAATCCTGCGATAGCAATACCAATAAAAAGTACAGT
+CCACGAAGGATAAACATTTTCAAGTGAAAAATCTTTTAAATATTTTATTGAAAAAATAAT
+CATATGCGTCATAATTCCCACAAGGCATAAAATCCAAATAGGCGTTATTAAGCTATTGAT
+AAAAGTTATGTTACTAAAAAATGTATTTAAATAAGTAGTACCTAAAAAGCCAGACATGAA
+AAATGTTGTGAACACTGATGAAACTAGAGGACTGTTTAATTGTTCTTTCACATTATTAAA
+ATATTTGATCATAGTACATAAAAGGTGAATCCAAATCAAGAAAGCAAAGATTCCGCAAAC
+AGCGTTTAAAGTAAGAGATAAGTCTTTTAATAGATTACCCAGGCCTAATAATCCTAAGAC
+TAGTCCTGACGTTACTAGAGGTGCTTTTTGAAGTCTCATGATTTACAACCTTTCTTATGT
+GATTTTCTTCACTAATTATATCATGATAGCTATGGCCAATTAATAAGAAGAGTGTGTACT
+ATTACGTTATTAGAGTATGTATATTGGATTGATAGACACATAATTGACATTTAAATCTCA
+AAATTAATGATATTTGAGGTATGCTTTGCAACCTAAATATTGGAATATGTGGAAAAGTAA
+TTATTTAATTTAAATGATGATTGAAGATTTACAAGGGGGTGTACAAAATGAGAAATCAAA
+TTCAAAAACTATTAGACAGTGATTTGAGCAGTTTACATATATCGAAACAAACAGGAGTTC
+CACAAAGCACAATACACAGAATGAGAAAAAAAGAAAGATCATTAGACAATATGTCATTGA
+AAAACGCTGAACTACTTTATAAATTTGCCAATAGTATATTTAGCAATGAAAATTAAGAAG
+AATAATTAGTGAGTTAAATAATTAAAAAACCACGTCTCGATGGACGTGGTTATTTTTTTA
+AATGTATTTAATTATAGGATTTCGGGCCCCTGAAAAGTCCCTAAAATTTTGAATAGTATC
+AAAATCTATAGGAATAATATAATAATAAAAATCTCTACGCATGCAAATGGTGAGTGTTAA
+AAATCTTGGTGTAGTGTTGGTGTAGTTCAGGTGCAGTATAGATGAAATTTGAGCACAAAA
+TTACTTAATTAAAAATGTATAAACAAGTGTCAGACGCGTGTCAATTGTGTGTCAAAAAAT
+TCTATGACGAATAAGCATGCTTGTTTTAATTACTGTATTTTCGGGGCTTATGCGGGGGAC
+GTTTTGGTGACGCATCATACTATATTACTGAAATTCAAAACAAAAAGAGCCCCGTAATCA
+CGGAACTCTTTTGTTTGGTAATGCGTATAAAAATACCTATAAACGTCCTGGGAGGGATTC
+GAACCCCCGACCGATGGCTTAGAAGGCCATTGCTCTATCCAGCTGAGCTACCAGGACACG
+TTTAACAACACAAGAATTATTATATCTAAATGAACTTAAATTAGCAATACCTTGTAAATA
+AAAAATGTTTATATTTTTCACTATTATAGAGCTATTTATCTAAAAAGGTTCAATAAGACT
+TAAATGCGAATTCAGGCAACTTAATTGTGTTAAATACAGTTTTGAATGCCTAACTGTATT
+TCTTTTCTCTTTAAAATACAGTTAAGTACATTATAAGATGTTGTGCGGATAAACAAACTA
+ATTGCATCAAATTTATTTTAAAATAACAACAACAAAACGTTAAGCGAATAACATTTCGGT
+GATTTAAAAGCTACGCACGTTTTTGTTATCTTCAAATTTAAATTTTAAGGAGTGTTTTCA
+ATGGAAGGTTTATTTAACGCAATTAAAGATACCGTAACTGCAGCAATTAATAATGATGGC
+GCAAAATTAGGCACAAGCATTGTGAGCATCGTTGAAAATGGCGTAGGTTTATTAGGTAAA
+TTATTCGGATTCTAATTTCAATATGTTATGTAAGTAATCAGTATTATTTCAAAGGTGAGG
+GAGAGATTTAAATGACTGGACTAGCAGAAGCAATCGCAAATACTGTGCAAGCTGCACAAC
+AACATGATAGTGTGAAATTAGGCACAAGTATCGTAGACATCGTTGCTAACGGTGTGGGTT
+TACTAGGTAAATTATTTGGATTCTAATATAATAACTAATATTCTTTAAAATAAACTGGGT
+GAGCATACTTTAATGTTATGCACTCAGTTTATTTTATTTGCAGAAATTTGAGCCTCTGTT
+AAGATTTAGATACATAGACAATATAGGAGATGGGGAAATTGGGATATAAAAATATTTTGA
+TAGACTTTGATGATACAATTGTTGATTTTTATGATGCAGAAGAATGGGCGTTTCACTATA
+TGGCGAATGTTTTTAATCATAAAGCAACAAAGGATGATTTTTTAACATTTAAAAAAATCA
+ATCACCAACATTGGGAAGCTTTTCAACAAAATAAATTAACGAAGTCTGAAGTATTATCAG
+AACGATTTGTGAATTACTTCAAACATCATCAAATGGAAGTTGATGGGCATCGTGCAGATG
+TGTTATTTAGAAATGGATTAGCAGAAGCTAAAGTTAAATACTTTGATCAAACATTAGAAA
+CAATTGTCGAATTATCGAAAAGACATGATTTATATATTGTTACTAATGGTGTAACCGAAA
+CGCAAAAGAGAAGGTTAAATCAGACGCCGTTGCATAAATATATTAAAAAGATATTTATAT
+CTGAGGAAACAGGATATCAAAAACCTAATCCGGAATTTTTTAATTATGTTTTTAATGATA
+TTGGTGAGGATGAAAGACAGCACTCGATTATAGTTGGAGATTCTTTAACATCTGACATTC
+TAGGTGGAATCAATGCGGGTATAGCTACTTGCTGGTTTAATTTTAGAGGATTTGATCATA
+ATCCAGGAATTATACCTGATTATGAAATTAATTCATGGAAACAACTAAATGATATTGTAC
+GTTAAGACAAATAATTTGAAAATGATTTATATTAGCTTAAGAAAGTAATTGTAAAAACGA
+CACTACGAAAAGATGCATTTTCATGCTCGTAGTGTCGAATATTATTATCTTATGGTTTCC
+ACAATAAGACATCATGTCCCTCTATATTTTTAGCTTCCACATCTGTAAATCCATGATGTA
+AAAAGAAATCCTTAGAATCATTTCTGCCAATGGCTTTAATTGGCATATTGAAACTCTTTG
+CAAAATCAATCAATTCTGAAGCGTACCCTCTGTTTTGATATTTTGGTAATACTTCTAACT
+TCCATAATAATATATAATCTTCAAAATCTGGGAAGTAGATTTCTTCGACATCACCTTTTT
+TTAGTAATGCCATTCTAGCTCCTAATTGATCTCCGACAAATATGCCATAAAATGGTGAAT
+CTGAACTTGCATCAATCATTTGACCGTTTAACTCATTGACCATGTATAAGTCTTTGTTGC
+CAAACGCTCTAAAGTTTTCGAATAATTCGTCAGTTTTGTAATTAATTTCAAGACGTTTGA
+TTTCACTCATATTTATCTACCCCTTATTTGTTTACTACTATTATTATACATTAAACCACT
+TGTGTTTTTCATTGATTTGAAAATGTAAAACAATGAACATTATAAATTTTCCATGATTAA
+ATTGATTTTCAAGCCGTAAAATTGTCAATCACCGGTATAGACTTTATACTATAGTTTGTA
+ATCGCGTACTTAAGGAGAAAAAACATGGACTGTAAAGTAGTTAGTTTAAATGAAAAAGAT
+CAGTTTATACCAAAAATAAAGAGCAGTGACCCTGTAATAACAGGATTATTTCAATATGAT
+GCAGCTCAACAAACTAGTTTTGAAAAAAGGATGTCTAAAGAAAATAATGGAAGAGAAGCG
+GCATTAGCGAATGTTATTCGTGAATATATGAGTGATTTAAAGCTTTCAAATGAACAAGAA
+TTAAACATACAACATTTAGCTAATGGTTCAAAAGTTGTGATTGGTGGACAACAAGCAGGG
+CTTTTCGGGGGACCATTGTATACATTCCATAAAATATTTTCAATCATTACTTTATCTAAG
+GAATTAACGGATACACATAAGCAACAAGTAGTACCAGTTTTTTGGATTGCAGGAGAAGAT
+CATGATTTCGATGAAGTGAATCATACATTTGTTTATAACGAAAATCATGGGTCGCTGCAT
+AAGGTTAAATATCATACAATGGAGATGCCAGAGACGACAGTCTCTAGATATTATCCTGAT
+AAGGCTGAGTTGAAACAAACTTTAAAAACGATGTTCATTCATATGAAAGAAACTGTTCAT
+ACACAAGGTCTACTGGAGATTTGTGACAGAATTATTGACCAATATGACTCGTGGACTGAT
+ATGTTTAAAGCACTACTGCATGAAACATTTAAAGCATATGGCGTTCTATTTATAGATGCG
+CAGTTTGAGCCGTTAAGAAAAATGGAAGCGCCTATGTTTAAAAAGATTTTGAAAAAACAT
+CAGTTGCTTGATGATGCTTTTAGAGCAACACAACAACGTACTCAAAATCAAGGCTTGAAT
+GCGATGATACAAACAGATACAAATGTTCATTTATTCTTACATGATGAAAATATGCGCCAA
+TTAGTTTCGTATGATGGTAAGCATTTTAAATTAAATAAAACAGATAAGACATATATAAAG
\ No newline at end of file
diff --git a/t/data/query_1_alternative_patterns.gff b/t/data/query_1_alternative_patterns.gff
new file mode 100644
index 0000000..99df45f
--- /dev/null
+++ b/t/data/query_1_alternative_patterns.gff
@@ -0,0 +1,262 @@
+##gff-version 3
+##sequence-region abc|SC|contig000001 1 15000
+abc|SC|contig000001 Prodigal:2.60 CDS 172 1131 . - 0 ID=1_1
+abc|SC|contig000001 Prodigal:2.60 CDS 1804 1950 . + 0 ID=abc_00002;
+abc|SC|contig000001 Prodigal:2.60 CDS 1934 2131 . + 0 ID=abc_00003;inference=ab initio
+abc|SC|contig000001 Prodigal:2.60 CDS 2621 3337 . - 0 ID="abc_00004";inference=ab initio prediction:Prodigal:2.60,protein motif:CLUSTERS:PRK13350,protein motif:Pfam:PF02876.11;locus_tag=abc_00004;product=superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain
+abc|SC|contig000001 Prodigal:2.60 CDS 3445 4170 . - 0 ID='1_2';gene=speH;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P0C0I6,protein motif:CLUSTERS:PRK13349,protein motif:Pfam:PF02876.11;locus_tag=abc_00005;note=SPE H;product='hypothetical protein,superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain';protein_id=gnl|SC|abc_00005
+abc|SC|contig000001 Prodigal:2.60 CDS 4265 4990 . - 0 id=abc_00006;inference=ab initio prediction:Prodigal:2.60,protein motif:CLUSTERS:PRK13043,protein motif:Pfam:PF02876.11;locus_tag=abc_00006;product="superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain";protein_id=gnl|SC|abc_00006
+
+##FASTA
+>abc|SC|contig000001
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
+ATACCCACCACATTTGGTGGAGAACCAAAAATTAGCCGAAAAACATCATTTCTGAAGTTA
+TCGGCTAAAGTTATAAATTATATTTATTTGTACATGAACAAATAATTTACATTAATTTGT
+CATTTCTTCTTTTTCCCAATCGATTTTATATCTTTCTGAAGAACGATCTGTCCATTTATC
+TTTAGTATTGGTACCTTTCCAATTTGTTGAAGTCCAATGCAATTGGTAGTCATCACGAAC
+TCGTTCGTATATTACATCTATATTTGTTTGTTGTTTGGATGCTTTTCTATCCATAGTAAT
+AACTGTAGCGAAGTCTGGTGAAAACCCTGAAGATAATAGAGAACTTGCTTTGTTAGGATC
+AAGGAAGTTCTCTGCTGCTTTCATAGAACCATTTCTAGTTTTCATGAAAAGTTGATTGCC
+ATATACCGGGTTCCAAGAATCTCTATCATATGGTCCCCAATTTTGATTCACCATATTGTT
+AAATATCACTTTCCAGCCTACTTTTTTATCAGTTGGGCTCTCTAAAATTGTTTTGAAATC
+AGGTTGAACATATTTCAGTGTATGACCAATCGAAACATTTGCACCAATAAGGCCGCCAAT
+TTTTCCTGTATCATCACCAGTAACATTACCGTTGAATCCATAAGTTAAAGTACTCATATA
+CTCTTTTGTATCAATCGAATTTCTTGGATAGTAATCAGATATTTGAGCTACTTCATTATC
+AGGTAGTTGCAACTGTACCTTAAAGGCTGAAGGCCAGGCTAAACCACTTTTGTTAGCACC
+TTCTTCGCTATAAACTCTATATTGACCAGCAATGGTACCTTTCGTTCTAATAACTAGCAG
+TTTTTTATTGTGATTTTTATCATCGATAAAACTATAAAATACTTTTTTGTGCATGCCATT
+TTCTTTATCATAAGTGACTAAATCACCTGTTTTTACTGTAGTATTGCTTCCAATATCTGT
+AGTACCGGTTTTAATATTAATATCAGAATCTGCGGCATTAGCGACAGGATTCATTAATAT
+GGAACCTAGCAATAGTGTTGTTGTTACTGAGCTGACTATACGTGTTTTCATTTTCATCAT
+CCTTCTATTTTTTTTAACGATTTGAGGAAACAATAATCAATATGTCAATTTAGAATATTG
+CAGTTGAGACATATCAAATATTTATAATCGTTTATATTAGTATATTTAATGTAGCAACTG
+ATAAATTACTGAGTGATGATGAGTGATTATTTTAAGAATATGTTTTTAACTTTTATTTAA
+AATTTGAAAGGAAGCATTTCAATTTCGAGGGTTAGTCAAAGTTGAATAAATTCTTTATGA
+AACAAGGAAAAGACATAGCTAATTTTATTGATTAATTTCTTTAAAACTAATGATTTGTTT
+GATTTAAAAATGTAATCGATTACAATATAAAAATACAAATATCTTAGAATTAAATCAATT
+AATTAACTATTAAATAAAAATTAAATATATATTAACTACTGTAAATTAATAAATAGAAAT
+AGAGAAAAAGGGTATTAATTATGTTTGGAATTTCGTCGGGAATAATTTTTGCCATTACAT
+AGAAATATCTAATAGATAATGAAAAAGTATCGTATGTATTTTTAATATAGTGTAAAATAT
+CATATGTAAAATAAAATGTAGATTTTTAGTTAGAGGCATTATAAGAAAATTTTGAGTATA
+GGTTAGCTTTTAATTATGAATCTTATTGAAATTTGATTAATAAATATATGATAGGGGATT
+AAAATGAAACTATTTTATATCGTATTTCTTATTATTATATGGCTGAATATATTTTTAGGA
+AATGAAATTATCCATACACTGACTGTTTTAATAACAACATTGTATATTGTTAATTCAAGA
+AAGGGGATTAAAAATGACAGAGTTGAATAATATTATAAACTCTCTTCAATCTTTGTTTGA
+GTCTGAATCAGGCTATAAAATTTCGAAAAATTCAGGAGTTCCATATCAAACAGTACAAGA
+TTTAAGAAATGGGAAAACCAAACTAGAAGATGCTAGATTTAGAACGATTATTAAACTTTA
+TAGTTACTATGTCTCATTAAAAGAACATTAATCATGGGACAATAAAGTATTGCTATAATA
+ATTGAATCATTAAATGAAGGAATAGAGCCTAAGACATAATAAATCAATGTCTTAGGCTCT
+ACAATATTATATTGGTAGTAGTTGACCGAATGAAAATGACCATGTAACAAGCATTTTTGG
+GGCCCCAACACAGAAGCTGACGAAAAGTCAGCTTACAATAATGTGCAAGTTGGGGATGGG
+CCCCAACACAGAGAATTTCAAAAAGAAATTCTACAGACAATGCAAGTTGGCGGGGCCCCA
+ACATAGAGAAATTCAAAAAGAAATTCTACAGACAATGCAAGTTGGGGAGTGACAACGAAA
+TAAATTTTATAAAATACCATTTCTGTCACATTCCTACTCCCAATTCCATTTAAATATATA
+GAAAATTTCACCTATTATATACATCATACACTTTAAAAATTATCATTTAAATAATCTGAT
+TTGGAATTAAAGTGCATGAAGTATAAGTCACCTTCATATACTAATCAAAGAGGACGTCAA
+CAGTTATTTTATTAGGATTTTTAACATAAACATTTGCTAGATCTGAATGTAATCTTTTGC
+TTAAATCAATAGTGTAGTTATTACCGCCACCGGTGATCTTAAGCTTACCTTTATTACGAT
+TTTCGGTATATAATATTTTATTTTTTATTAACGCTTCTCGTGCACGGAAATCGATTTCTT
+TCAATGTTAATACTGGTTTATTGCCTTGGTATATTTTATGCGCACCAATAATCGTTTGTA
+GTTTATCTTTGTATTGCACAAAAAGATTATAAGTTTTATCAGAAGGTTTTGCGGCTGGTG
+TAACGCCACCTGTAAATGTCTCTCTATAAGACCACCATAACTGATCAGTATCTTTGTCTT
+TTAGTCCAAACACATCTACGTAACGATCTTTTAACTGATTAATATTTCCCCAACTTTCAG
+CGCCCCATAAAGATATATGTGCTGACCATGAATATCTCTTAAGTTCAACATAAATGTTTC
+CATTATCATATTGATATAGCCATTTATTTGAAAATGAAAAATGAGGCTGTGTGTAATATT
+TAATTAATTCATTGATGTTAGTTTCATCTTGACCAATGCTATAAGCTTTAGCTTCAGAGT
+AAAAACTAAATACTGGTTTTTGATTTTGAGGTAATACAGTACCTAATAGTAATAATGTTG
+TCGTTAAAATTATATTTTTCGTGATGTTCTTACTCATTAGAACATCTCCTTTCAGAGGAA
+TCATGATACGAGGAATAAGAAATTTAAATGTGAGCGAAGTCAATATAGTATTTGCGATTA
+TTTTTATTAACTCCATTATTATTGTTAGTTTGATTTTTCGAGGATAACTTCAATTTTTGC
+ATTTTGAGGTTTTTTAACATATCTATTTGCATCAGTTGATGGCAACCTTTTACTTAAATC
+TATTGTGTAGTTATTGTCTGTACCTGTTATTTTAATTTGTCCTTTATTATAAGAATTATT
+ATATAATTTTTTACTTTTAATTAATGTTTGACGAATACGAAAATCTAATTCTTTTAAAGT
+TAAAACAGGCTTATTGCCTTCATAAACTGGAAATCCGCCAGTAAACGTTTCTGCTTTATC
+TTTATATGTTACATTCAGTTTATAGTGTTTATCGTTAGATGTTGCTGCAGGAGTAACACC
+ACCAGTAAACGTTTCTTGAGATAATGCAAAAGAATCAATGGTTTCTTGGTCTTTTATGCC
+AAAAATATCAACGCTTTTATTTCTTAATTGGTTGATATTGCCCCAACTTTCAGGTCCATA
+AACTTGAATATGACTATACCAAGAAAACTGTAACAACGTTGCATGAATCGTACCGTTATC
+TTTTTGCCATAACGTACTGTTAGAGAAGGTTAAATATTTTTGCGAGTAATATTTAGTTAA
+CTCATTAACGTTAGTTTCGTTTTGATTTATATAATAAGCTTTCGCTTCAGATGAAGAATT
+GATAGGTGTATTAGGAAATTGTGTAAATGCTGTACCTAATAGTAACAATGTTGTTGATAA
+AATAATTTTTTTCGTGATGTTATTGTTCATTCGAATTTCTCCTTTGAGTATTGTTGGAAT
+GTTTAATTATAAAAAGGGGTTAATTAGATAATTGAAATTATCCGCATTTACAAAAGGTAA
+TAGGTTAGTTAGATTTTTCGAGTATGACTTCAATTTGTGCATTTTTAGGATTTTTAACAT
+AACGGTTTGTGTCAGTTAATTTTAACTTTTTACTTAAATCAATCGTGTAATTATTTCCAT
+CAGCAGTTATCTTAATTTGACCTTTATTAAATTCTCCGTTATATAACTTTTTATTCTTTA
+TTAATGTTTGACGAATACGGAAATCTAATTCTTTTAAAGTTAATACTGGTTTATTTCCTT
+TGTAAAATTCATGTCCACCGATGATAGTTTGTTGTTTATCACTATATTTTAAAAATAGTC
+TATAAGGTTTATCAGATGAAGTAGCTGCTGGCGTAACACCACCAGTAAATGTTTCATCAT
+AAGTCCAGTAACCTTCAACTGTGTCCTCATCTTTAGTTCCAAATATATCAACGTATTTAT
+TTCTTAACTGATTAATGTTTCCCCAACTCTCGGATCCAAACACTTGAATATGACTATACC
+AAACCCACGTTTGCAATGTTGCATGAATGCTACCATTGGGCTTTTGCCATAGCCATTTTC
+CAGATAATGAAAAATGCGGCTGAGTGTAATATTTGATTAACTCATTGATATTAGTCTCGT
+TTTCACTGATATTATAGGCTTTTGCTTCAGATGAAAAACTGATTGGTGTTTTAGGAAGTT
+GTGTTGATGTGGTTCCTAAAAGTAACAATGCTGTTGATAAAACTAATTTATTCATGATGT
+TCTTTTTCATATGAAAATCTCCTTTGCGTGAATTACCCAAAGTATATAAGCTATTACACC
+GATTCGGAATTAAATAAAAGCTAAAACTATGTTAAATAAACTTAAACAGTTAGTAGTGTT
+ATTTAAGCAAAACTTATCATTTTTAAGTTTTGGACAGAAACAGTACTTAATAAAGTAGGC
+GGGAGTTATATATTAAAAACGACACGTTACAATTATTCTCTAATCAATTGCATTAAATTG
+TTTGATAATTGAATTTTCTAACTACTTGAAAAATAGTTATACTTTAAATGTAGTACTTAT
+TTTAATTATTTCCTACTACTTAAATTTAATATTAATAAAATGTTCATTTAATTATTGATA
+AAATATTACAAATTTTAATAGTAGGTTGTGTTTATTTTGTATGCGCTTACAATTTAGGTG
+TAACTAAAATAAAAGGAGTTGTTATTAATGAAAAATTTACGAAACAGAAGTTTTTTAACT
+TTATTAGACTTTTCACGACAAGAGGTAGAATTCTTATTAACACTCTCCGAGGATTTAAAA
+CGTGCTAAATATATTGGCACTGAAAAGCCTATGTTAAAAAATAAAAATATTGCACTGTTA
+TTTGAAAAAGATTCTACAAGAACGCGATGTGCATTTGAAGTTGCAGCGCATGATCAAGGT
+GCAAATGTAACTTATTTAGGCCCAACTGGATCACAAATGGGTAAAAAAGAAACAACTAAA
+GATACTGCACGTGTGCTTGGTGGAATGTATGATGGCATTGAATACCGTGGTTTTTCACAA
+AGAACAGTAGAAACTTTAGCTGAAAATTCAGGCGTACCAGTGTGGAATGGTTTAACTGAT
+GAAGATCATCCTACTCAAGTTCTTGCTGATTTCTTAACAGCAAAAGAAGTCTTAAAAAAA
+GATTATGCAGATATTAACTTTACATATGTTGGAGATGGTCGTAATAACGTTGCAAATGCA
+TTAATGCAAGGTGCTGCCATTATGGGTATGAACTTCCATTTAGTTTGTCCAAAAGAATTA
+AATCCAACAGATGAATTATTAAATCGCTGTAAAAATATTGCCGCTGAAAATGGTGGCAAC
+ATATTAATCACAGATGATATTGACCAAGGTGTAAAAGGTTCGGATGTAATTTACACTGAT
+GTTTGGGTATCAATGGGTGAACCTGATGAAGTATGGAAAGAACGACTTGAATTATTGAAA
+CCATATCAAGTAAATAAAGAAATGATGGATAAAACTGGTAATCCAAATGTTATTTTTGAG
+CATTGCTTACCATCTTTCCATAATGCTGATACGAAAATTGGTCAACAAATTTTTGAAAAA
+TATGGTATTCGAGAAATGGAAGTTACAGATGAAGTATTCGAAAGTAAAGCTTCAGTTGTA
+TTCCAAGAAGCTGAGAACAGAATGCATACAATCAAAGCAGTCATGGTTGCTACATTGGGT
+GAATTTTAAATGATATAAGGAAGTGAATATGATGGCGAAAATAGTAGTAGCATTAGGTGG
+TAATGCTTTAGGAAAATCACCTCAAGAACAACTCGAGCTTGTTAAAAATACTGCGAAATC
+ATTAGTAGGATTAATAACAAAAGGACATGAGATTGTTATTAGTCATGGTAATGGACCACA
+GGTTGGAAGCATTAATTTGGGACTTAACTATGCTGCAGAACATAACCAAGGTCCGGCATT
+TCCATTTGCTGAATGTGGCGCAATGAGTCAAGCTTACATCGGCTATCAATTACAAGAAAG
+CTTACAAAATGAATTGCATTCTATTGGAATGGATAAACAAGTGGTAACACTAGTGACACA
+AGTTGAAGTTGATGAAAATGATCCGGCATTTAACAATCCTTCAAAACCAATTGGGTTATT
+TTACAACAAAGAAGAAGCTGAACAAATTCAAAAAGAAAAAGGATTTATATTTGTTGAAGA
+TGCTGGAAGAGGATATAGACGCGTTGTTCCTTCACCACAACCCATCTCTATTATTGAATT
+AGAGAGTATTAAAACACTTATTAAAAATGATACACTCGTTATTGCTGCTGGTGGTGGAGG
+TATACCAGTAATTAGAGAGCAACATGATGGTTTTAAAGGTATTGATGCAGTTATAGACAA
+AGATAAAACAAGTGCGTTGTTGGGTGCTAATATTCAATGCGATCAATTGATTATTTTAAC
+AGCAATTGATTATGTATATATTAATTTTAACACTGAAAACCAACAGCCTTTGAAAACAAC
+AAATGTTGATGAATTAAAACGATATATAGACGAAAATCAATTTGCAAAAGGAAGTATGTT
+ACCAAAAATTGAAGCAGCCATATCATTTATTGAAAACAATCCAAAAGGAAGTGTGCTTAT
+AACATCATTAAATGAATTAGATGCTGCCTTAGAGGGTAAAGTAGGTACTGTGATTAAAAA
+GTAATTGAATTGAAACGCTTTTCAATTACTATATGTCAAATGCATGATTTTTATTATTTA
+TGTGCACCCCCTGAAAATAATGCCTCTATTTTGATGCGGGGTGCACTTTCTTAATTTATA
+TTTATAAAATCTTTAAGGTAGAAATGCTAGGTTAAATGTCGAAGGAGATGAAACCGTGGA
+AAATACAATTAATGAAAGTGAAAAGAAAAAACGATTTAAATTAAAAATGCCAGGTGCATT
+TATGATTTTATTCATTTTAACGGTTGTTGCAGTTATAGCAACATGGGTTATTCCTGCTGG
+TGCATATTCTAAACTTTCTTACGAACCTTCATCCCAAGAACTAAAGATAGTTAACCCTCA
+TAACCAAGTGAAAAAGGTTCCGGGTACGCAACAGGAACTAGACAAAATGGGGGTTAAAAT
+TAAGATTGAACAATTTAAATCAGGTGCAATTAATAAGCCAGTATCAATTCCGAATACTTA
+TGAAAGATTAAAGCAACATCCAGCTGGACCAGAACAAATAACAAGTAGCATGGTTGAAGG
+TACGATAGAAGCGGTCGATATCATGGTATTCATTCTTGTACTAGGGGGACTTATTGGCGT
+AGTTCAAGCCAGTGGTTCTTTTGAATCGGGATTGTTAGCTTTAACGAAGAAAACAAAAGG
+GCATGAATTTATGCTAATTGTGTTTGTATCAATACTAATGATTATCGGCGGGACGTTATG
+TGGTATTGAAGAAGAAGCTGTAGCATTCTATCCGATTTTAGTCCCTATATTTATAGCGTT
+AGGATACGATTCTATCGTTTCAGTTGGTGCCATATTCCTTGCCAGCTCTGTCGGTAGTAC
+ATTTTCAACTATTAACCCGTTCTCGGTTGTAATTGCCTCTAATGCCGCTGGTACAACTTT
+TACGGATGGCTTGTATTGGAGAATAGGTGCTTGTATTGTCGGTGCGATTTTTGTTATTAG
+TTATTTATATTGGTACTGTAAAAAAATTAAAAACGATCCTAAAGCGTCATATTCTTATGA
+AGACAAAGATGCTTTTGAACAGCAATGGTCTGTATTAAAAGATGACGATAGTGCCCATTT
+TACTTTGCGTAAGAAGATAATCCTTACATTATTTGTACTACCATTTCCAATTATGGTATG
+GGGAGTTATGACGCAAGGTTGGTGGTTCCCAGTTATGGCTTCAGCATTTTTAATATTTAC
+AATTATAATAATGTTTATTGCTGGGACAGGTAAATCTGGATTGGGAGAAAAAGGAACTGT
+AGATGCATTTGTCAATGGTGCATCAAGTTTAGTAGGTGTATCTTTAATTATTGGTTTAGC
+TCGAGGTATTAATTTAGTGTTGAATGAAGGTATGATTTCAGATACAATCTTACACTTTTC
+ATCATCTTTAGTTCAACATATGAGTGGACCATTATTTATCATCGTATTACTATTTATTTT
+CTTCTGTTTAGGTTTTATCGTGCCATCATCTTCTGGATTAGCGGTATTATCAATGCCTAT
+CTTTGCACCACTAGCTGATACAGTAGGTATACCAAGATTCGTCATCGTTACGACATATCA
+ATTTGGTCAATATGCGATGTTATTCTTAGCGCCGACTGGACTTGTTATGGCCACACTACA
+AATGTTAAACATGCGATATTCACATTGGTTCCGATTTGTATGGCCGGTAGTTGCTTTTGT
+ATTGATTTTCGGTGGCGGAGTACTAATTACGCAAGTACTAATTTATTCATAATTTGAAAT
+GCTATATTATAAAAATACTAATTGGGTTTTATGCATCTCGTAGGTTTGTAGAAATACTAA
+ACTAAGCGAGGTGCATTATTATTTTTGATTAAGAAAATAATGACGGTAATGATAACACTA
+GTAAGTAATTGATACAATGCTCTATTTAATAATGATATTTTTAAAATTTGTTTTTAATGT
+AATGTTAGATCTATGGTATATTATATTTATCGTGGTAAATATGTATTTGCTGTAAACAGT
+TTTTGTAACACATGACACATATGGTTGTGAAAATAGCATATATAAAGGATGGCTATAAAT
+GACACATTTGACAAAGGTTTTAGATACACTAACTGGAATATGCGTAGTATTATTATTTAG
+TAAATATTTTGTGGCGTATGCAAATATGGTGTTTGATTGGAATTTAAGATGGTATTTGCT
+AGAAAACATACCACATTTGCCAATTATATTATTTATTCTGATGTTTATTTTCGGAGTACC
+TTCTGAAATGATAAAAGATAGGCAAAGGAAAAATAACGGTGTTTAATTTATCGATATTTA
+GAGGTGATAAAATTTGTCAACTATTACAAAGACTAAAATAAAAATCTTTATTAATTATTT
+TATTGGTATATTAGCCTTGGCGTTTGCTGCTTATATATTATTTAAATAAAGGTTAGAGTG
+AAACGTGTTTATGAACTAGACGTTCTAGTATAGTTACTACAGCTTTAGTCAGAAGGTATC
+ATTGATAAGATCATATTAAATCAAAGAGGCATTGATATACACTAAAAAGAGGCAAGATTA
+CCTGCCTCTTTTTTAGTTATTAAATATGCGTGTTAATTCTTGGTAATAGTGTTACTGAGA
+CGCATTACGAAGAAATTTATCTTGATTTTCCTTTTTTAAAAAGAAGTGAAGATATCCTAT
+AAAGACTCTAAGTACTATTACAGTGGCTAATAACACTTCGATAAACAAAAGACCTTTCCA
+AATATCTGGAAACATAAGTACAGGCAAACTGTTCTTTAAAGCAGTTGCTGAGATTACTAA
+AGGGAATGTGAAAGCTGAAAATACGGGCGAAAAAGGTTCTTTTAGTAATTTAGGCAATTG
+TATAATGATATAAAAATAAAATATTTGAGCTAATATTAAAAATATAATTACGATAAAAGC
+ATTCGCCTTAGGAAAGGCTATAACATATGCTGCAGCGACTAAAGAAAATGGTGCACAAAT
+TGTCGATGTGTTCGGTTTGATTGACGTCTGCAATGGAAATGCTTTTAATCGCTTGAAAAC
+AATAGGTAAGACAATACAAGTAGCTACAAAGCCATATATTACTGTTAATTGACCTATGAA
+AAAACATCCGCTAACGGGTGCCGTCAATCCTGCGATAGCAATACCAATAAAAAGTACAGT
+CCACGAAGGATAAACATTTTCAAGTGAAAAATCTTTTAAATATTTTATTGAAAAAATAAT
+CATATGCGTCATAATTCCCACAAGGCATAAAATCCAAATAGGCGTTATTAAGCTATTGAT
+AAAAGTTATGTTACTAAAAAATGTATTTAAATAAGTAGTACCTAAAAAGCCAGACATGAA
+AAATGTTGTGAACACTGATGAAACTAGAGGACTGTTTAATTGTTCTTTCACATTATTAAA
+ATATTTGATCATAGTACATAAAAGGTGAATCCAAATCAAGAAAGCAAAGATTCCGCAAAC
+AGCGTTTAAAGTAAGAGATAAGTCTTTTAATAGATTACCCAGGCCTAATAATCCTAAGAC
+TAGTCCTGACGTTACTAGAGGTGCTTTTTGAAGTCTCATGATTTACAACCTTTCTTATGT
+GATTTTCTTCACTAATTATATCATGATAGCTATGGCCAATTAATAAGAAGAGTGTGTACT
+ATTACGTTATTAGAGTATGTATATTGGATTGATAGACACATAATTGACATTTAAATCTCA
+AAATTAATGATATTTGAGGTATGCTTTGCAACCTAAATATTGGAATATGTGGAAAAGTAA
+TTATTTAATTTAAATGATGATTGAAGATTTACAAGGGGGTGTACAAAATGAGAAATCAAA
+TTCAAAAACTATTAGACAGTGATTTGAGCAGTTTACATATATCGAAACAAACAGGAGTTC
+CACAAAGCACAATACACAGAATGAGAAAAAAAGAAAGATCATTAGACAATATGTCATTGA
+AAAACGCTGAACTACTTTATAAATTTGCCAATAGTATATTTAGCAATGAAAATTAAGAAG
+AATAATTAGTGAGTTAAATAATTAAAAAACCACGTCTCGATGGACGTGGTTATTTTTTTA
+AATGTATTTAATTATAGGATTTCGGGCCCCTGAAAAGTCCCTAAAATTTTGAATAGTATC
+AAAATCTATAGGAATAATATAATAATAAAAATCTCTACGCATGCAAATGGTGAGTGTTAA
+AAATCTTGGTGTAGTGTTGGTGTAGTTCAGGTGCAGTATAGATGAAATTTGAGCACAAAA
+TTACTTAATTAAAAATGTATAAACAAGTGTCAGACGCGTGTCAATTGTGTGTCAAAAAAT
+TCTATGACGAATAAGCATGCTTGTTTTAATTACTGTATTTTCGGGGCTTATGCGGGGGAC
+GTTTTGGTGACGCATCATACTATATTACTGAAATTCAAAACAAAAAGAGCCCCGTAATCA
+CGGAACTCTTTTGTTTGGTAATGCGTATAAAAATACCTATAAACGTCCTGGGAGGGATTC
+GAACCCCCGACCGATGGCTTAGAAGGCCATTGCTCTATCCAGCTGAGCTACCAGGACACG
+TTTAACAACACAAGAATTATTATATCTAAATGAACTTAAATTAGCAATACCTTGTAAATA
+AAAAATGTTTATATTTTTCACTATTATAGAGCTATTTATCTAAAAAGGTTCAATAAGACT
+TAAATGCGAATTCAGGCAACTTAATTGTGTTAAATACAGTTTTGAATGCCTAACTGTATT
+TCTTTTCTCTTTAAAATACAGTTAAGTACATTATAAGATGTTGTGCGGATAAACAAACTA
+ATTGCATCAAATTTATTTTAAAATAACAACAACAAAACGTTAAGCGAATAACATTTCGGT
+GATTTAAAAGCTACGCACGTTTTTGTTATCTTCAAATTTAAATTTTAAGGAGTGTTTTCA
+ATGGAAGGTTTATTTAACGCAATTAAAGATACCGTAACTGCAGCAATTAATAATGATGGC
+GCAAAATTAGGCACAAGCATTGTGAGCATCGTTGAAAATGGCGTAGGTTTATTAGGTAAA
+TTATTCGGATTCTAATTTCAATATGTTATGTAAGTAATCAGTATTATTTCAAAGGTGAGG
+GAGAGATTTAAATGACTGGACTAGCAGAAGCAATCGCAAATACTGTGCAAGCTGCACAAC
+AACATGATAGTGTGAAATTAGGCACAAGTATCGTAGACATCGTTGCTAACGGTGTGGGTT
+TACTAGGTAAATTATTTGGATTCTAATATAATAACTAATATTCTTTAAAATAAACTGGGT
+GAGCATACTTTAATGTTATGCACTCAGTTTATTTTATTTGCAGAAATTTGAGCCTCTGTT
+AAGATTTAGATACATAGACAATATAGGAGATGGGGAAATTGGGATATAAAAATATTTTGA
+TAGACTTTGATGATACAATTGTTGATTTTTATGATGCAGAAGAATGGGCGTTTCACTATA
+TGGCGAATGTTTTTAATCATAAAGCAACAAAGGATGATTTTTTAACATTTAAAAAAATCA
+ATCACCAACATTGGGAAGCTTTTCAACAAAATAAATTAACGAAGTCTGAAGTATTATCAG
+AACGATTTGTGAATTACTTCAAACATCATCAAATGGAAGTTGATGGGCATCGTGCAGATG
+TGTTATTTAGAAATGGATTAGCAGAAGCTAAAGTTAAATACTTTGATCAAACATTAGAAA
+CAATTGTCGAATTATCGAAAAGACATGATTTATATATTGTTACTAATGGTGTAACCGAAA
+CGCAAAAGAGAAGGTTAAATCAGACGCCGTTGCATAAATATATTAAAAAGATATTTATAT
+CTGAGGAAACAGGATATCAAAAACCTAATCCGGAATTTTTTAATTATGTTTTTAATGATA
+TTGGTGAGGATGAAAGACAGCACTCGATTATAGTTGGAGATTCTTTAACATCTGACATTC
+TAGGTGGAATCAATGCGGGTATAGCTACTTGCTGGTTTAATTTTAGAGGATTTGATCATA
+ATCCAGGAATTATACCTGATTATGAAATTAATTCATGGAAACAACTAAATGATATTGTAC
+GTTAAGACAAATAATTTGAAAATGATTTATATTAGCTTAAGAAAGTAATTGTAAAAACGA
+CACTACGAAAAGATGCATTTTCATGCTCGTAGTGTCGAATATTATTATCTTATGGTTTCC
+ACAATAAGACATCATGTCCCTCTATATTTTTAGCTTCCACATCTGTAAATCCATGATGTA
+AAAAGAAATCCTTAGAATCATTTCTGCCAATGGCTTTAATTGGCATATTGAAACTCTTTG
+CAAAATCAATCAATTCTGAAGCGTACCCTCTGTTTTGATATTTTGGTAATACTTCTAACT
+TCCATAATAATATATAATCTTCAAAATCTGGGAAGTAGATTTCTTCGACATCACCTTTTT
+TTAGTAATGCCATTCTAGCTCCTAATTGATCTCCGACAAATATGCCATAAAATGGTGAAT
+CTGAACTTGCATCAATCATTTGACCGTTTAACTCATTGACCATGTATAAGTCTTTGTTGC
+CAAACGCTCTAAAGTTTTCGAATAATTCGTCAGTTTTGTAATTAATTTCAAGACGTTTGA
+TTTCACTCATATTTATCTACCCCTTATTTGTTTACTACTATTATTATACATTAAACCACT
+TGTGTTTTTCATTGATTTGAAAATGTAAAACAATGAACATTATAAATTTTCCATGATTAA
+ATTGATTTTCAAGCCGTAAAATTGTCAATCACCGGTATAGACTTTATACTATAGTTTGTA
+ATCGCGTACTTAAGGAGAAAAAACATGGACTGTAAAGTAGTTAGTTTAAATGAAAAAGAT
+CAGTTTATACCAAAAATAAAGAGCAGTGACCCTGTAATAACAGGATTATTTCAATATGAT
+GCAGCTCAACAAACTAGTTTTGAAAAAAGGATGTCTAAAGAAAATAATGGAAGAGAAGCG
+GCATTAGCGAATGTTATTCGTGAATATATGAGTGATTTAAAGCTTTCAAATGAACAAGAA
+TTAAACATACAACATTTAGCTAATGGTTCAAAAGTTGTGATTGGTGGACAACAAGCAGGG
+CTTTTCGGGGGACCATTGTATACATTCCATAAAATATTTTCAATCATTACTTTATCTAAG
+GAATTAACGGATACACATAAGCAACAAGTAGTACCAGTTTTTTGGATTGCAGGAGAAGAT
+CATGATTTCGATGAAGTGAATCATACATTTGTTTATAACGAAAATCATGGGTCGCTGCAT
+AAGGTTAAATATCATACAATGGAGATGCCAGAGACGACAGTCTCTAGATATTATCCTGAT
+AAGGCTGAGTTGAAACAAACTTTAAAAACGATGTTCATTCATATGAAAGAAACTGTTCAT
+ACACAAGGTCTACTGGAGATTTGTGACAGAATTATTGACCAATATGACTCGTGGACTGAT
+ATGTTTAAAGCACTACTGCATGAAACATTTAAAGCATATGGCGTTCTATTTATAGATGCG
+CAGTTTGAGCCGTTAAGAAAAATGGAAGCGCCTATGTTTAAAAAGATTTTGAAAAAACAT
+CAGTTGCTTGATGATGCTTTTAGAGCAACACAACAACGTACTCAAAATCAAGGCTTGAAT
+GCGATGATACAAACAGATACAAATGTTCATTTATTCTTACATGATGAAAATATGCGCCAA
+TTAGTTTCGTATGATGGTAAGCATTTTAAATTAAATAAAACAGATAAGACATATATAAAG
\ No newline at end of file
diff --git a/t/data/query_2.fa b/t/data/query_2.fa
new file mode 100644
index 0000000..e80478e
--- /dev/null
+++ b/t/data/query_2.fa
@@ -0,0 +1,8 @@
+>2_1
+AAA
+>2_2
+BBB
+>2_4
+DDD
+>2_7
+GGG
\ No newline at end of file
diff --git a/t/data/query_2.gff b/t/data/query_2.gff
new file mode 100644
index 0000000..b93ffcc
--- /dev/null
+++ b/t/data/query_2.gff
@@ -0,0 +1,271 @@
+##gff-version 3
+##sequence-region abc|SC|contig000001 1 15000
+abc|SC|contig000001 Prodigal:2.60 CDS 172 1131 . - 0 ID=2_1;gene=hly;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:Q2G1X0,protein motif:TIGRFAMs:TIGR01002,protein motif:Pfam:PF07968.6;locus_tag=abc_00001;product=Alpha-toxin,beta-channel forming cytolysin,Leukocidin/Hemolysin toxin family protein;protein_id=gnl|SC|abc_00001
+abc|SC|contig000001 Prodigal:2.60 CDS 1804 1950 . + 0 ID=abc_00002;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00002;product=hypothetical protein;protein_id=gnl|SC|abc_00002
+abc|SC|contig000001 Prodigal:2.60 CDS 1934 2131 . + 0 ID=abc_00003;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00003;product=hypothetical protein;protein_id=gnl|SC|abc_00003
+abc|SC|contig000001 Prodigal:2.60 CDS 2621 3337 . - 0 ID=abc_00004;inference=ab initio prediction:Prodigal:2.60,protein motif:CLUSTERS:PRK13350,protein motif:Pfam:PF02876.11;locus_tag=abc_00004;product=superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00004
+abc|SC|contig000001 Prodigal:2.60 CDS 3445 4170 . - 0 ID=2_2;gene=speH;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P0C0I6,protein motif:CLUSTERS:PRK13349,protein motif:Pfam:PF02876.11;locus_tag=abc_00005;note=SPE H;product=hypothetical protein,superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00005
+abc|SC|contig000001 Prodigal:2.60 CDS 4265 4990 . - 0 ID=abc_00006;inference=ab initio prediction:Prodigal:2.60,protein motif:CLUSTERS:PRK13043,protein motif:Pfam:PF02876.11;locus_tag=abc_00006;product=superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00006
+abc|SC|contig000001 Prodigal:2.60 CDS 5428 6429 . + 0 ID=2_3;eC_number=2.1.3.3;gene=argF;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P99073,protein motif:CLUSTERS:PRK04284,protein motif:Cdd:COG0078,protein motif:TIGRFAMs:TIGR00658,protein motif:Pfam:PF00185.1;locus_tag=abc_00007;product=Ornithine carbamoyltransferase,ornithine carbamoyltransferase,Ornithine carbamoyltransferase,ornithine carbamoyltransferase,Aspartate/ornithine carbamoyltransferase%2C As [...]
+abc|SC|contig000001 Prodigal:2.60 CDS 6449 7384 . + 0 ID=abc_00008;eC_number=2.7.2.2;gene=arcC1;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:Q7A627,protein motif:CLUSTERS:PRK12353,protein motif:TIGRFAMs:TIGR00746,protein motif:Pfam:PF00696.22;locus_tag=abc_00008;product=Carbamate kinase 1,putative amino acid kinase,carbamate kinase,Amino acid kinase family protein;protein_id=gnl|SC|abc_00008
+abc|SC|contig000001 RNAmmer:1.2 rRNA 7556 9112 . + 0 ID=abc_01705;inference=COORDINATES:profile:RNAmmer:1.2;locus_tag=abc_01705;product=16S ribosomal RNA
+abc|SC|contig000001 Prodigal:2.60 CDS 9419 9646 . + 0 ID=abc_00010;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00010;product=hypothetical protein;protein_id=gnl|SC|abc_00010
+abc|SC|contig000001 Prodigal:2.60 CDS 9952 10899 . - 0 ID=abc_00011;inference=ab initio prediction:Prodigal:2.60,protein motif:Pfam:PF03595.11;locus_tag=abc_00011;product=C4-dicarboxylate transporter/malic acid transport protein;protein_id=gnl|SC|abc_00011
+abc|SC|contig000001 Prodigal:2.60 CDS 11148 11336 . + 0 ID=abc_00012;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00012;product=hypothetical protein;protein_id=gnl|SC|abc_00012
+abc|SC|contig000001 Aragorn:1.2.34 tRNA 11803 11878 . - 0 ID=abc_00013;inference=COORDINATES:profile:Aragorn:1.2.34;locus_tag=abc_00013;product=tRNA-Arg(tct)
+abc|SC|contig000001 Prodigal:2.60 CDS 12241 12375 . + 0 ID=abc_00014;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P11699,protein motif:Pfam:PF05480.5;locus_tag=abc_00014;product=Gonococcal growth inhibitor III,Staphylococcus haemolytic protein;protein_id=gnl|SC|abc_00014
+abc|SC|contig000001 Prodigal:2.60 CDS 12432 12566 . + 0 ID=2_7;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P11699,protein motif:Pfam:PF05480.5;locus_tag=abc_00015;product=Gonococcal growth inhibitor III,Staphylococcus haemolytic protein;protein_id=gnl|SC|abc_00015
+abc|SC|contig000001 Prodigal:2.60 CDS 12699 13385 . + 0 ID=abc_00016;eC_number=3.-.-.-;gene=yfnB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:O06480,protein motif:CLUSTERS:PRK09449,protein motif:TIGRFAMs:TIGR02254,protein motif:Pfam:PF00702.1;locus_tag=abc_00016;product=Putative HAD-hydrolase yfnB,dUMP phosphatase,HAD hydrolase,haloacid dehalogenase-like hydrolase;protein_id=gnl|SC|abc_00016
+##FASTA
+>abc|SC|contig000001
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
+ATACCCACCACATTTGGTGGAGAACCAAAAATTAGCCGAAAAACATCATTTCTGAAGTTA
+TCGGCTAAAGTTATAAATTATATTTATTTGTACATGAACAAATAATTTACATTAATTTGT
+CATTTCTTCTTTTTCCCAATCGATTTTATATCTTTCTGAAGAACGATCTGTCCATTTATC
+TTTAGTATTGGTACCTTTCCAATTTGTTGAAGTCCAATGCAATTGGTAGTCATCACGAAC
+TCGTTCGTATATTACATCTATATTTGTTTGTTGTTTGGATGCTTTTCTATCCATAGTAAT
+AACTGTAGCGAAGTCTGGTGAAAACCCTGAAGATAATAGAGAACTTGCTTTGTTAGGATC
+AAGGAAGTTCTCTGCTGCTTTCATAGAACCATTTCTAGTTTTCATGAAAAGTTGATTGCC
+ATATACCGGGTTCCAAGAATCTCTATCATATGGTCCCCAATTTTGATTCACCATATTGTT
+AAATATCACTTTCCAGCCTACTTTTTTATCAGTTGGGCTCTCTAAAATTGTTTTGAAATC
+AGGTTGAACATATTTCAGTGTATGACCAATCGAAACATTTGCACCAATAAGGCCGCCAAT
+TTTTCCTGTATCATCACCAGTAACATTACCGTTGAATCCATAAGTTAAAGTACTCATATA
+CTCTTTTGTATCAATCGAATTTCTTGGATAGTAATCAGATATTTGAGCTACTTCATTATC
+AGGTAGTTGCAACTGTACCTTAAAGGCTGAAGGCCAGGCTAAACCACTTTTGTTAGCACC
+TTCTTCGCTATAAACTCTATATTGACCAGCAATGGTACCTTTCGTTCTAATAACTAGCAG
+TTTTTTATTGTGATTTTTATCATCGATAAAACTATAAAATACTTTTTTGTGCATGCCATT
+TTCTTTATCATAAGTGACTAAATCACCTGTTTTTACTGTAGTATTGCTTCCAATATCTGT
+AGTACCGGTTTTAATATTAATATCAGAATCTGCGGCATTAGCGACAGGATTCATTAATAT
+GGAACCTAGCAATAGTGTTGTTGTTACTGAGCTGACTATACGTGTTTTCATTTTCATCAT
+CCTTCTATTTTTTTTAACGATTTGAGGAAACAATAATCAATATGTCAATTTAGAATATTG
+CAGTTGAGACATATCAAATATTTATAATCGTTTATATTAGTATATTTAATGTAGCAACTG
+ATAAATTACTGAGTGATGATGAGTGATTATTTTAAGAATATGTTTTTAACTTTTATTTAA
+AATTTGAAAGGAAGCATTTCAATTTCGAGGGTTAGTCAAAGTTGAATAAATTCTTTATGA
+AACAAGGAAAAGACATAGCTAATTTTATTGATTAATTTCTTTAAAACTAATGATTTGTTT
+GATTTAAAAATGTAATCGATTACAATATAAAAATACAAATATCTTAGAATTAAATCAATT
+AATTAACTATTAAATAAAAATTAAATATATATTAACTACTGTAAATTAATAAATAGAAAT
+AGAGAAAAAGGGTATTAATTATGTTTGGAATTTCGTCGGGAATAATTTTTGCCATTACAT
+AGAAATATCTAATAGATAATGAAAAAGTATCGTATGTATTTTTAATATAGTGTAAAATAT
+CATATGTAAAATAAAATGTAGATTTTTAGTTAGAGGCATTATAAGAAAATTTTGAGTATA
+GGTTAGCTTTTAATTATGAATCTTATTGAAATTTGATTAATAAATATATGATAGGGGATT
+AAAATGAAACTATTTTATATCGTATTTCTTATTATTATATGGCTGAATATATTTTTAGGA
+AATGAAATTATCCATACACTGACTGTTTTAATAACAACATTGTATATTGTTAATTCAAGA
+AAGGGGATTAAAAATGACAGAGTTGAATAATATTATAAACTCTCTTCAATCTTTGTTTGA
+GTCTGAATCAGGCTATAAAATTTCGAAAAATTCAGGAGTTCCATATCAAACAGTACAAGA
+TTTAAGAAATGGGAAAACCAAACTAGAAGATGCTAGATTTAGAACGATTATTAAACTTTA
+TAGTTACTATGTCTCATTAAAAGAACATTAATCATGGGACAATAAAGTATTGCTATAATA
+ATTGAATCATTAAATGAAGGAATAGAGCCTAAGACATAATAAATCAATGTCTTAGGCTCT
+ACAATATTATATTGGTAGTAGTTGACCGAATGAAAATGACCATGTAACAAGCATTTTTGG
+GGCCCCAACACAGAAGCTGACGAAAAGTCAGCTTACAATAATGTGCAAGTTGGGGATGGG
+CCCCAACACAGAGAATTTCAAAAAGAAATTCTACAGACAATGCAAGTTGGCGGGGCCCCA
+ACATAGAGAAATTCAAAAAGAAATTCTACAGACAATGCAAGTTGGGGAGTGACAACGAAA
+TAAATTTTATAAAATACCATTTCTGTCACATTCCTACTCCCAATTCCATTTAAATATATA
+GAAAATTTCACCTATTATATACATCATACACTTTAAAAATTATCATTTAAATAATCTGAT
+TTGGAATTAAAGTGCATGAAGTATAAGTCACCTTCATATACTAATCAAAGAGGACGTCAA
+CAGTTATTTTATTAGGATTTTTAACATAAACATTTGCTAGATCTGAATGTAATCTTTTGC
+TTAAATCAATAGTGTAGTTATTACCGCCACCGGTGATCTTAAGCTTACCTTTATTACGAT
+TTTCGGTATATAATATTTTATTTTTTATTAACGCTTCTCGTGCACGGAAATCGATTTCTT
+TCAATGTTAATACTGGTTTATTGCCTTGGTATATTTTATGCGCACCAATAATCGTTTGTA
+GTTTATCTTTGTATTGCACAAAAAGATTATAAGTTTTATCAGAAGGTTTTGCGGCTGGTG
+TAACGCCACCTGTAAATGTCTCTCTATAAGACCACCATAACTGATCAGTATCTTTGTCTT
+TTAGTCCAAACACATCTACGTAACGATCTTTTAACTGATTAATATTTCCCCAACTTTCAG
+CGCCCCATAAAGATATATGTGCTGACCATGAATATCTCTTAAGTTCAACATAAATGTTTC
+CATTATCATATTGATATAGCCATTTATTTGAAAATGAAAAATGAGGCTGTGTGTAATATT
+TAATTAATTCATTGATGTTAGTTTCATCTTGACCAATGCTATAAGCTTTAGCTTCAGAGT
+AAAAACTAAATACTGGTTTTTGATTTTGAGGTAATACAGTACCTAATAGTAATAATGTTG
+TCGTTAAAATTATATTTTTCGTGATGTTCTTACTCATTAGAACATCTCCTTTCAGAGGAA
+TCATGATACGAGGAATAAGAAATTTAAATGTGAGCGAAGTCAATATAGTATTTGCGATTA
+TTTTTATTAACTCCATTATTATTGTTAGTTTGATTTTTCGAGGATAACTTCAATTTTTGC
+ATTTTGAGGTTTTTTAACATATCTATTTGCATCAGTTGATGGCAACCTTTTACTTAAATC
+TATTGTGTAGTTATTGTCTGTACCTGTTATTTTAATTTGTCCTTTATTATAAGAATTATT
+ATATAATTTTTTACTTTTAATTAATGTTTGACGAATACGAAAATCTAATTCTTTTAAAGT
+TAAAACAGGCTTATTGCCTTCATAAACTGGAAATCCGCCAGTAAACGTTTCTGCTTTATC
+TTTATATGTTACATTCAGTTTATAGTGTTTATCGTTAGATGTTGCTGCAGGAGTAACACC
+ACCAGTAAACGTTTCTTGAGATAATGCAAAAGAATCAATGGTTTCTTGGTCTTTTATGCC
+AAAAATATCAACGCTTTTATTTCTTAATTGGTTGATATTGCCCCAACTTTCAGGTCCATA
+AACTTGAATATGACTATACCAAGAAAACTGTAACAACGTTGCATGAATCGTACCGTTATC
+TTTTTGCCATAACGTACTGTTAGAGAAGGTTAAATATTTTTGCGAGTAATATTTAGTTAA
+CTCATTAACGTTAGTTTCGTTTTGATTTATATAATAAGCTTTCGCTTCAGATGAAGAATT
+GATAGGTGTATTAGGAAATTGTGTAAATGCTGTACCTAATAGTAACAATGTTGTTGATAA
+AATAATTTTTTTCGTGATGTTATTGTTCATTCGAATTTCTCCTTTGAGTATTGTTGGAAT
+GTTTAATTATAAAAAGGGGTTAATTAGATAATTGAAATTATCCGCATTTACAAAAGGTAA
+TAGGTTAGTTAGATTTTTCGAGTATGACTTCAATTTGTGCATTTTTAGGATTTTTAACAT
+AACGGTTTGTGTCAGTTAATTTTAACTTTTTACTTAAATCAATCGTGTAATTATTTCCAT
+CAGCAGTTATCTTAATTTGACCTTTATTAAATTCTCCGTTATATAACTTTTTATTCTTTA
+TTAATGTTTGACGAATACGGAAATCTAATTCTTTTAAAGTTAATACTGGTTTATTTCCTT
+TGTAAAATTCATGTCCACCGATGATAGTTTGTTGTTTATCACTATATTTTAAAAATAGTC
+TATAAGGTTTATCAGATGAAGTAGCTGCTGGCGTAACACCACCAGTAAATGTTTCATCAT
+AAGTCCAGTAACCTTCAACTGTGTCCTCATCTTTAGTTCCAAATATATCAACGTATTTAT
+TTCTTAACTGATTAATGTTTCCCCAACTCTCGGATCCAAACACTTGAATATGACTATACC
+AAACCCACGTTTGCAATGTTGCATGAATGCTACCATTGGGCTTTTGCCATAGCCATTTTC
+CAGATAATGAAAAATGCGGCTGAGTGTAATATTTGATTAACTCATTGATATTAGTCTCGT
+TTTCACTGATATTATAGGCTTTTGCTTCAGATGAAAAACTGATTGGTGTTTTAGGAAGTT
+GTGTTGATGTGGTTCCTAAAAGTAACAATGCTGTTGATAAAACTAATTTATTCATGATGT
+TCTTTTTCATATGAAAATCTCCTTTGCGTGAATTACCCAAAGTATATAAGCTATTACACC
+GATTCGGAATTAAATAAAAGCTAAAACTATGTTAAATAAACTTAAACAGTTAGTAGTGTT
+ATTTAAGCAAAACTTATCATTTTTAAGTTTTGGACAGAAACAGTACTTAATAAAGTAGGC
+GGGAGTTATATATTAAAAACGACACGTTACAATTATTCTCTAATCAATTGCATTAAATTG
+TTTGATAATTGAATTTTCTAACTACTTGAAAAATAGTTATACTTTAAATGTAGTACTTAT
+TTTAATTATTTCCTACTACTTAAATTTAATATTAATAAAATGTTCATTTAATTATTGATA
+AAATATTACAAATTTTAATAGTAGGTTGTGTTTATTTTGTATGCGCTTACAATTTAGGTG
+TAACTAAAATAAAAGGAGTTGTTATTAATGAAAAATTTACGAAACAGAAGTTTTTTAACT
+TTATTAGACTTTTCACGACAAGAGGTAGAATTCTTATTAACACTCTCCGAGGATTTAAAA
+CGTGCTAAATATATTGGCACTGAAAAGCCTATGTTAAAAAATAAAAATATTGCACTGTTA
+TTTGAAAAAGATTCTACAAGAACGCGATGTGCATTTGAAGTTGCAGCGCATGATCAAGGT
+GCAAATGTAACTTATTTAGGCCCAACTGGATCACAAATGGGTAAAAAAGAAACAACTAAA
+GATACTGCACGTGTGCTTGGTGGAATGTATGATGGCATTGAATACCGTGGTTTTTCACAA
+AGAACAGTAGAAACTTTAGCTGAAAATTCAGGCGTACCAGTGTGGAATGGTTTAACTGAT
+GAAGATCATCCTACTCAAGTTCTTGCTGATTTCTTAACAGCAAAAGAAGTCTTAAAAAAA
+GATTATGCAGATATTAACTTTACATATGTTGGAGATGGTCGTAATAACGTTGCAAATGCA
+TTAATGCAAGGTGCTGCCATTATGGGTATGAACTTCCATTTAGTTTGTCCAAAAGAATTA
+AATCCAACAGATGAATTATTAAATCGCTGTAAAAATATTGCCGCTGAAAATGGTGGCAAC
+ATATTAATCACAGATGATATTGACCAAGGTGTAAAAGGTTCGGATGTAATTTACACTGAT
+GTTTGGGTATCAATGGGTGAACCTGATGAAGTATGGAAAGAACGACTTGAATTATTGAAA
+CCATATCAAGTAAATAAAGAAATGATGGATAAAACTGGTAATCCAAATGTTATTTTTGAG
+CATTGCTTACCATCTTTCCATAATGCTGATACGAAAATTGGTCAACAAATTTTTGAAAAA
+TATGGTATTCGAGAAATGGAAGTTACAGATGAAGTATTCGAAAGTAAAGCTTCAGTTGTA
+TTCCAAGAAGCTGAGAACAGAATGCATACAATCAAAGCAGTCATGGTTGCTACATTGGGT
+GAATTTTAAATGATATAAGGAAGTGAATATGATGGCGAAAATAGTAGTAGCATTAGGTGG
+TAATGCTTTAGGAAAATCACCTCAAGAACAACTCGAGCTTGTTAAAAATACTGCGAAATC
+ATTAGTAGGATTAATAACAAAAGGACATGAGATTGTTATTAGTCATGGTAATGGACCACA
+GGTTGGAAGCATTAATTTGGGACTTAACTATGCTGCAGAACATAACCAAGGTCCGGCATT
+TCCATTTGCTGAATGTGGCGCAATGAGTCAAGCTTACATCGGCTATCAATTACAAGAAAG
+CTTACAAAATGAATTGCATTCTATTGGAATGGATAAACAAGTGGTAACACTAGTGACACA
+AGTTGAAGTTGATGAAAATGATCCGGCATTTAACAATCCTTCAAAACCAATTGGGTTATT
+TTACAACAAAGAAGAAGCTGAACAAATTCAAAAAGAAAAAGGATTTATATTTGTTGAAGA
+TGCTGGAAGAGGATATAGACGCGTTGTTCCTTCACCACAACCCATCTCTATTATTGAATT
+AGAGAGTATTAAAACACTTATTAAAAATGATACACTCGTTATTGCTGCTGGTGGTGGAGG
+TATACCAGTAATTAGAGAGCAACATGATGGTTTTAAAGGTATTGATGCAGTTATAGACAA
+AGATAAAACAAGTGCGTTGTTGGGTGCTAATATTCAATGCGATCAATTGATTATTTTAAC
+AGCAATTGATTATGTATATATTAATTTTAACACTGAAAACCAACAGCCTTTGAAAACAAC
+AAATGTTGATGAATTAAAACGATATATAGACGAAAATCAATTTGCAAAAGGAAGTATGTT
+ACCAAAAATTGAAGCAGCCATATCATTTATTGAAAACAATCCAAAAGGAAGTGTGCTTAT
+AACATCATTAAATGAATTAGATGCTGCCTTAGAGGGTAAAGTAGGTACTGTGATTAAAAA
+GTAATTGAATTGAAACGCTTTTCAATTACTATATGTCAAATGCATGATTTTTATTATTTA
+TGTGCACCCCCTGAAAATAATGCCTCTATTTTGATGCGGGGTGCACTTTCTTAATTTATA
+TTTATAAAATCTTTAAGGTAGAAATGCTAGGTTAAATGTCGAAGGAGATGAAACCGTGGA
+AAATACAATTAATGAAAGTGAAAAGAAAAAACGATTTAAATTAAAAATGCCAGGTGCATT
+TATGATTTTATTCATTTTAACGGTTGTTGCAGTTATAGCAACATGGGTTATTCCTGCTGG
+TGCATATTCTAAACTTTCTTACGAACCTTCATCCCAAGAACTAAAGATAGTTAACCCTCA
+TAACCAAGTGAAAAAGGTTCCGGGTACGCAACAGGAACTAGACAAAATGGGGGTTAAAAT
+TAAGATTGAACAATTTAAATCAGGTGCAATTAATAAGCCAGTATCAATTCCGAATACTTA
+TGAAAGATTAAAGCAACATCCAGCTGGACCAGAACAAATAACAAGTAGCATGGTTGAAGG
+TACGATAGAAGCGGTCGATATCATGGTATTCATTCTTGTACTAGGGGGACTTATTGGCGT
+AGTTCAAGCCAGTGGTTCTTTTGAATCGGGATTGTTAGCTTTAACGAAGAAAACAAAAGG
+GCATGAATTTATGCTAATTGTGTTTGTATCAATACTAATGATTATCGGCGGGACGTTATG
+TGGTATTGAAGAAGAAGCTGTAGCATTCTATCCGATTTTAGTCCCTATATTTATAGCGTT
+AGGATACGATTCTATCGTTTCAGTTGGTGCCATATTCCTTGCCAGCTCTGTCGGTAGTAC
+ATTTTCAACTATTAACCCGTTCTCGGTTGTAATTGCCTCTAATGCCGCTGGTACAACTTT
+TACGGATGGCTTGTATTGGAGAATAGGTGCTTGTATTGTCGGTGCGATTTTTGTTATTAG
+TTATTTATATTGGTACTGTAAAAAAATTAAAAACGATCCTAAAGCGTCATATTCTTATGA
+AGACAAAGATGCTTTTGAACAGCAATGGTCTGTATTAAAAGATGACGATAGTGCCCATTT
+TACTTTGCGTAAGAAGATAATCCTTACATTATTTGTACTACCATTTCCAATTATGGTATG
+GGGAGTTATGACGCAAGGTTGGTGGTTCCCAGTTATGGCTTCAGCATTTTTAATATTTAC
+AATTATAATAATGTTTATTGCTGGGACAGGTAAATCTGGATTGGGAGAAAAAGGAACTGT
+AGATGCATTTGTCAATGGTGCATCAAGTTTAGTAGGTGTATCTTTAATTATTGGTTTAGC
+TCGAGGTATTAATTTAGTGTTGAATGAAGGTATGATTTCAGATACAATCTTACACTTTTC
+ATCATCTTTAGTTCAACATATGAGTGGACCATTATTTATCATCGTATTACTATTTATTTT
+CTTCTGTTTAGGTTTTATCGTGCCATCATCTTCTGGATTAGCGGTATTATCAATGCCTAT
+CTTTGCACCACTAGCTGATACAGTAGGTATACCAAGATTCGTCATCGTTACGACATATCA
+ATTTGGTCAATATGCGATGTTATTCTTAGCGCCGACTGGACTTGTTATGGCCACACTACA
+AATGTTAAACATGCGATATTCACATTGGTTCCGATTTGTATGGCCGGTAGTTGCTTTTGT
+ATTGATTTTCGGTGGCGGAGTACTAATTACGCAAGTACTAATTTATTCATAATTTGAAAT
+GCTATATTATAAAAATACTAATTGGGTTTTATGCATCTCGTAGGTTTGTAGAAATACTAA
+ACTAAGCGAGGTGCATTATTATTTTTGATTAAGAAAATAATGACGGTAATGATAACACTA
+GTAAGTAATTGATACAATGCTCTATTTAATAATGATATTTTTAAAATTTGTTTTTAATGT
+AATGTTAGATCTATGGTATATTATATTTATCGTGGTAAATATGTATTTGCTGTAAACAGT
+TTTTGTAACACATGACACATATGGTTGTGAAAATAGCATATATAAAGGATGGCTATAAAT
+GACACATTTGACAAAGGTTTTAGATACACTAACTGGAATATGCGTAGTATTATTATTTAG
+TAAATATTTTGTGGCGTATGCAAATATGGTGTTTGATTGGAATTTAAGATGGTATTTGCT
+AGAAAACATACCACATTTGCCAATTATATTATTTATTCTGATGTTTATTTTCGGAGTACC
+TTCTGAAATGATAAAAGATAGGCAAAGGAAAAATAACGGTGTTTAATTTATCGATATTTA
+GAGGTGATAAAATTTGTCAACTATTACAAAGACTAAAATAAAAATCTTTATTAATTATTT
+TATTGGTATATTAGCCTTGGCGTTTGCTGCTTATATATTATTTAAATAAAGGTTAGAGTG
+AAACGTGTTTATGAACTAGACGTTCTAGTATAGTTACTACAGCTTTAGTCAGAAGGTATC
+ATTGATAAGATCATATTAAATCAAAGAGGCATTGATATACACTAAAAAGAGGCAAGATTA
+CCTGCCTCTTTTTTAGTTATTAAATATGCGTGTTAATTCTTGGTAATAGTGTTACTGAGA
+CGCATTACGAAGAAATTTATCTTGATTTTCCTTTTTTAAAAAGAAGTGAAGATATCCTAT
+AAAGACTCTAAGTACTATTACAGTGGCTAATAACACTTCGATAAACAAAAGACCTTTCCA
+AATATCTGGAAACATAAGTACAGGCAAACTGTTCTTTAAAGCAGTTGCTGAGATTACTAA
+AGGGAATGTGAAAGCTGAAAATACGGGCGAAAAAGGTTCTTTTAGTAATTTAGGCAATTG
+TATAATGATATAAAAATAAAATATTTGAGCTAATATTAAAAATATAATTACGATAAAAGC
+ATTCGCCTTAGGAAAGGCTATAACATATGCTGCAGCGACTAAAGAAAATGGTGCACAAAT
+TGTCGATGTGTTCGGTTTGATTGACGTCTGCAATGGAAATGCTTTTAATCGCTTGAAAAC
+AATAGGTAAGACAATACAAGTAGCTACAAAGCCATATATTACTGTTAATTGACCTATGAA
+AAAACATCCGCTAACGGGTGCCGTCAATCCTGCGATAGCAATACCAATAAAAAGTACAGT
+CCACGAAGGATAAACATTTTCAAGTGAAAAATCTTTTAAATATTTTATTGAAAAAATAAT
+CATATGCGTCATAATTCCCACAAGGCATAAAATCCAAATAGGCGTTATTAAGCTATTGAT
+AAAAGTTATGTTACTAAAAAATGTATTTAAATAAGTAGTACCTAAAAAGCCAGACATGAA
+AAATGTTGTGAACACTGATGAAACTAGAGGACTGTTTAATTGTTCTTTCACATTATTAAA
+ATATTTGATCATAGTACATAAAAGGTGAATCCAAATCAAGAAAGCAAAGATTCCGCAAAC
+AGCGTTTAAAGTAAGAGATAAGTCTTTTAATAGATTACCCAGGCCTAATAATCCTAAGAC
+TAGTCCTGACGTTACTAGAGGTGCTTTTTGAAGTCTCATGATTTACAACCTTTCTTATGT
+GATTTTCTTCACTAATTATATCATGATAGCTATGGCCAATTAATAAGAAGAGTGTGTACT
+ATTACGTTATTAGAGTATGTATATTGGATTGATAGACACATAATTGACATTTAAATCTCA
+AAATTAATGATATTTGAGGTATGCTTTGCAACCTAAATATTGGAATATGTGGAAAAGTAA
+TTATTTAATTTAAATGATGATTGAAGATTTACAAGGGGGTGTACAAAATGAGAAATCAAA
+TTCAAAAACTATTAGACAGTGATTTGAGCAGTTTACATATATCGAAACAAACAGGAGTTC
+CACAAAGCACAATACACAGAATGAGAAAAAAAGAAAGATCATTAGACAATATGTCATTGA
+AAAACGCTGAACTACTTTATAAATTTGCCAATAGTATATTTAGCAATGAAAATTAAGAAG
+AATAATTAGTGAGTTAAATAATTAAAAAACCACGTCTCGATGGACGTGGTTATTTTTTTA
+AATGTATTTAATTATAGGATTTCGGGCCCCTGAAAAGTCCCTAAAATTTTGAATAGTATC
+AAAATCTATAGGAATAATATAATAATAAAAATCTCTACGCATGCAAATGGTGAGTGTTAA
+AAATCTTGGTGTAGTGTTGGTGTAGTTCAGGTGCAGTATAGATGAAATTTGAGCACAAAA
+TTACTTAATTAAAAATGTATAAACAAGTGTCAGACGCGTGTCAATTGTGTGTCAAAAAAT
+TCTATGACGAATAAGCATGCTTGTTTTAATTACTGTATTTTCGGGGCTTATGCGGGGGAC
+GTTTTGGTGACGCATCATACTATATTACTGAAATTCAAAACAAAAAGAGCCCCGTAATCA
+CGGAACTCTTTTGTTTGGTAATGCGTATAAAAATACCTATAAACGTCCTGGGAGGGATTC
+GAACCCCCGACCGATGGCTTAGAAGGCCATTGCTCTATCCAGCTGAGCTACCAGGACACG
+TTTAACAACACAAGAATTATTATATCTAAATGAACTTAAATTAGCAATACCTTGTAAATA
+AAAAATGTTTATATTTTTCACTATTATAGAGCTATTTATCTAAAAAGGTTCAATAAGACT
+TAAATGCGAATTCAGGCAACTTAATTGTGTTAAATACAGTTTTGAATGCCTAACTGTATT
+TCTTTTCTCTTTAAAATACAGTTAAGTACATTATAAGATGTTGTGCGGATAAACAAACTA
+ATTGCATCAAATTTATTTTAAAATAACAACAACAAAACGTTAAGCGAATAACATTTCGGT
+GATTTAAAAGCTACGCACGTTTTTGTTATCTTCAAATTTAAATTTTAAGGAGTGTTTTCA
+ATGGAAGGTTTATTTAACGCAATTAAAGATACCGTAACTGCAGCAATTAATAATGATGGC
+GCAAAATTAGGCACAAGCATTGTGAGCATCGTTGAAAATGGCGTAGGTTTATTAGGTAAA
+TTATTCGGATTCTAATTTCAATATGTTATGTAAGTAATCAGTATTATTTCAAAGGTGAGG
+GAGAGATTTAAATGACTGGACTAGCAGAAGCAATCGCAAATACTGTGCAAGCTGCACAAC
+AACATGATAGTGTGAAATTAGGCACAAGTATCGTAGACATCGTTGCTAACGGTGTGGGTT
+TACTAGGTAAATTATTTGGATTCTAATATAATAACTAATATTCTTTAAAATAAACTGGGT
+GAGCATACTTTAATGTTATGCACTCAGTTTATTTTATTTGCAGAAATTTGAGCCTCTGTT
+AAGATTTAGATACATAGACAATATAGGAGATGGGGAAATTGGGATATAAAAATATTTTGA
+TAGACTTTGATGATACAATTGTTGATTTTTATGATGCAGAAGAATGGGCGTTTCACTATA
+TGGCGAATGTTTTTAATCATAAAGCAACAAAGGATGATTTTTTAACATTTAAAAAAATCA
+ATCACCAACATTGGGAAGCTTTTCAACAAAATAAATTAACGAAGTCTGAAGTATTATCAG
+AACGATTTGTGAATTACTTCAAACATCATCAAATGGAAGTTGATGGGCATCGTGCAGATG
+TGTTATTTAGAAATGGATTAGCAGAAGCTAAAGTTAAATACTTTGATCAAACATTAGAAA
+CAATTGTCGAATTATCGAAAAGACATGATTTATATATTGTTACTAATGGTGTAACCGAAA
+CGCAAAAGAGAAGGTTAAATCAGACGCCGTTGCATAAATATATTAAAAAGATATTTATAT
+CTGAGGAAACAGGATATCAAAAACCTAATCCGGAATTTTTTAATTATGTTTTTAATGATA
+TTGGTGAGGATGAAAGACAGCACTCGATTATAGTTGGAGATTCTTTAACATCTGACATTC
+TAGGTGGAATCAATGCGGGTATAGCTACTTGCTGGTTTAATTTTAGAGGATTTGATCATA
+ATCCAGGAATTATACCTGATTATGAAATTAATTCATGGAAACAACTAAATGATATTGTAC
+GTTAAGACAAATAATTTGAAAATGATTTATATTAGCTTAAGAAAGTAATTGTAAAAACGA
+CACTACGAAAAGATGCATTTTCATGCTCGTAGTGTCGAATATTATTATCTTATGGTTTCC
+ACAATAAGACATCATGTCCCTCTATATTTTTAGCTTCCACATCTGTAAATCCATGATGTA
+AAAAGAAATCCTTAGAATCATTTCTGCCAATGGCTTTAATTGGCATATTGAAACTCTTTG
+CAAAATCAATCAATTCTGAAGCGTACCCTCTGTTTTGATATTTTGGTAATACTTCTAACT
+TCCATAATAATATATAATCTTCAAAATCTGGGAAGTAGATTTCTTCGACATCACCTTTTT
+TTAGTAATGCCATTCTAGCTCCTAATTGATCTCCGACAAATATGCCATAAAATGGTGAAT
+CTGAACTTGCATCAATCATTTGACCGTTTAACTCATTGACCATGTATAAGTCTTTGTTGC
+CAAACGCTCTAAAGTTTTCGAATAATTCGTCAGTTTTGTAATTAATTTCAAGACGTTTGA
+TTTCACTCATATTTATCTACCCCTTATTTGTTTACTACTATTATTATACATTAAACCACT
+TGTGTTTTTCATTGATTTGAAAATGTAAAACAATGAACATTATAAATTTTCCATGATTAA
+ATTGATTTTCAAGCCGTAAAATTGTCAATCACCGGTATAGACTTTATACTATAGTTTGTA
+ATCGCGTACTTAAGGAGAAAAAACATGGACTGTAAAGTAGTTAGTTTAAATGAAAAAGAT
+CAGTTTATACCAAAAATAAAGAGCAGTGACCCTGTAATAACAGGATTATTTCAATATGAT
+GCAGCTCAACAAACTAGTTTTGAAAAAAGGATGTCTAAAGAAAATAATGGAAGAGAAGCG
+GCATTAGCGAATGTTATTCGTGAATATATGAGTGATTTAAAGCTTTCAAATGAACAAGAA
+TTAAACATACAACATTTAGCTAATGGTTCAAAAGTTGTGATTGGTGGACAACAAGCAGGG
+CTTTTCGGGGGACCATTGTATACATTCCATAAAATATTTTCAATCATTACTTTATCTAAG
+GAATTAACGGATACACATAAGCAACAAGTAGTACCAGTTTTTTGGATTGCAGGAGAAGAT
+CATGATTTCGATGAAGTGAATCATACATTTGTTTATAACGAAAATCATGGGTCGCTGCAT
+AAGGTTAAATATCATACAATGGAGATGCCAGAGACGACAGTCTCTAGATATTATCCTGAT
+AAGGCTGAGTTGAAACAAACTTTAAAAACGATGTTCATTCATATGAAAGAAACTGTTCAT
+ACACAAGGTCTACTGGAGATTTGTGACAGAATTATTGACCAATATGACTCGTGGACTGAT
+ATGTTTAAAGCACTACTGCATGAAACATTTAAAGCATATGGCGTTCTATTTATAGATGCG
+CAGTTTGAGCCGTTAAGAAAAATGGAAGCGCCTATGTTTAAAAAGATTTTGAAAAAACAT
+CAGTTGCTTGATGATGCTTTTAGAGCAACACAACAACGTACTCAAAATCAAGGCTTGAAT
+GCGATGATACAAACAGATACAAATGTTCATTTATTCTTACATGATGAAAATATGCGCCAA
+TTAGTTTCGTATGATGGTAAGCATTTTAAATTAAATAAAACAGATAAGACATATATAAAG
\ No newline at end of file
diff --git a/t/data/query_3.fa b/t/data/query_3.fa
new file mode 100644
index 0000000..fca5b3b
--- /dev/null
+++ b/t/data/query_3.fa
@@ -0,0 +1,8 @@
+>3_1
+AAA
+>3_3
+CCC
+>3_4
+DDD
+>3_5
+EEE
\ No newline at end of file
diff --git a/t/data/query_3.gff b/t/data/query_3.gff
new file mode 100644
index 0000000..4cc9dd9
--- /dev/null
+++ b/t/data/query_3.gff
@@ -0,0 +1,271 @@
+##gff-version 3
+##sequence-region abc|SC|contig000001 1 15000
+abc|SC|contig000001 Prodigal:2.60 CDS 172 1131 . - 0 ID=3_1;gene=hly;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:Q2G1X0,protein motif:TIGRFAMs:TIGR01002,protein motif:Pfam:PF07968.6;locus_tag=abc_00001;product=Alpha-toxin,beta-channel forming cytolysin,Leukocidin/Hemolysin toxin family protein;protein_id=gnl|SC|abc_00001
+abc|SC|contig000001 Prodigal:2.60 CDS 1804 1950 . + 0 ID=abc_00002;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00002;product=hypothetical protein;protein_id=gnl|SC|abc_00002
+abc|SC|contig000001 Prodigal:2.60 CDS 1934 2131 . + 0 ID=abc_00003;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00003;product=hypothetical protein;protein_id=gnl|SC|abc_00003
+abc|SC|contig000001 Prodigal:2.60 CDS 2621 3337 . - 0 ID=abc_00004;inference=ab initio prediction:Prodigal:2.60,protein motif:CLUSTERS:PRK13350,protein motif:Pfam:PF02876.11;locus_tag=abc_00004;product=superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00004
+abc|SC|contig000001 Prodigal:2.60 CDS 3445 4170 . - 0 ID=3_2;gene=speH;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P0C0I6,protein motif:CLUSTERS:PRK13349,protein motif:Pfam:PF02876.11;locus_tag=abc_00005;note=SPE H;product=hypothetical protein,superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00005
+abc|SC|contig000001 Prodigal:2.60 CDS 4265 4990 . - 0 ID=abc_00006;inference=ab initio prediction:Prodigal:2.60,protein motif:CLUSTERS:PRK13043,protein motif:Pfam:PF02876.11;locus_tag=abc_00006;product=superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00006
+abc|SC|contig000001 Prodigal:2.60 CDS 5428 6429 . + 0 ID=3_3;eC_number=2.1.3.3;gene=argF;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P99073,protein motif:CLUSTERS:PRK04284,protein motif:Cdd:COG0078,protein motif:TIGRFAMs:TIGR00658,protein motif:Pfam:PF00185.1;locus_tag=abc_00007;product=Ornithine carbamoyltransferase,ornithine carbamoyltransferase,Ornithine carbamoyltransferase,ornithine carbamoyltransferase,Aspartate/ornithine carbamoyltransferase%2C As [...]
+abc|SC|contig000001 Prodigal:2.60 CDS 6449 7384 . + 0 ID=abc_00008;eC_number=2.7.2.2;gene=arcC1;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:Q7A627,protein motif:CLUSTERS:PRK12353,protein motif:TIGRFAMs:TIGR00746,protein motif:Pfam:PF00696.22;locus_tag=abc_00008;product=Carbamate kinase 1,putative amino acid kinase,carbamate kinase,Amino acid kinase family protein;protein_id=gnl|SC|abc_00008
+abc|SC|contig000001 RNAmmer:1.2 rRNA 7556 9112 . + 0 ID=abc_01705;inference=COORDINATES:profile:RNAmmer:1.2;locus_tag=abc_01705;product=16S ribosomal RNA
+abc|SC|contig000001 Prodigal:2.60 CDS 9419 9646 . + 0 ID=abc_00010;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00010;product=hypothetical protein;protein_id=gnl|SC|abc_00010
+abc|SC|contig000001 Prodigal:2.60 CDS 9952 10899 . - 0 ID=abc_00011;inference=ab initio prediction:Prodigal:2.60,protein motif:Pfam:PF03595.11;locus_tag=abc_00011;product=C4-dicarboxylate transporter/malic acid transport protein;protein_id=gnl|SC|abc_00011
+abc|SC|contig000001 Prodigal:2.60 CDS 11148 11336 . + 0 ID=abc_00012;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00012;product=hypothetical protein;protein_id=gnl|SC|abc_00012
+abc|SC|contig000001 Aragorn:1.2.34 tRNA 11803 11878 . - 0 ID=abc_00013;inference=COORDINATES:profile:Aragorn:1.2.34;locus_tag=abc_00013;product=tRNA-Arg(tct)
+abc|SC|contig000001 Prodigal:2.60 CDS 12241 12375 . + 0 ID=abc_00014;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P11699,protein motif:Pfam:PF05480.5;locus_tag=abc_00014;product=Gonococcal growth inhibitor III,Staphylococcus haemolytic protein;protein_id=gnl|SC|abc_00014
+abc|SC|contig000001 Prodigal:2.60 CDS 12432 12566 . + 0 ID=abc_00015;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P11699,protein motif:Pfam:PF05480.5;locus_tag=abc_00015;product=Gonococcal growth inhibitor III,Staphylococcus haemolytic protein;protein_id=gnl|SC|abc_00015
+abc|SC|contig000001 Prodigal:2.60 CDS 12699 13385 . + 0 ID=3_5;eC_number=3.-.-.-;gene=yfnB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:O06480,protein motif:CLUSTERS:PRK09449,protein motif:TIGRFAMs:TIGR02254,protein motif:Pfam:PF00702.1;locus_tag=abc_00016;product=Putative HAD-hydrolase yfnB,dUMP phosphatase,HAD hydrolase,haloacid dehalogenase-like hydrolase;protein_id=gnl|SC|abc_00016
+##FASTA
+>abc|SC|contig000001
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
+ATACCCACCACATTTGGTGGAGAACCAAAAATTAGCCGAAAAACATCATTTCTGAAGTTA
+TCGGCTAAAGTTATAAATTATATTTATTTGTACATGAACAAATAATTTACATTAATTTGT
+CATTTCTTCTTTTTCCCAATCGATTTTATATCTTTCTGAAGAACGATCTGTCCATTTATC
+TTTAGTATTGGTACCTTTCCAATTTGTTGAAGTCCAATGCAATTGGTAGTCATCACGAAC
+TCGTTCGTATATTACATCTATATTTGTTTGTTGTTTGGATGCTTTTCTATCCATAGTAAT
+AACTGTAGCGAAGTCTGGTGAAAACCCTGAAGATAATAGAGAACTTGCTTTGTTAGGATC
+AAGGAAGTTCTCTGCTGCTTTCATAGAACCATTTCTAGTTTTCATGAAAAGTTGATTGCC
+ATATACCGGGTTCCAAGAATCTCTATCATATGGTCCCCAATTTTGATTCACCATATTGTT
+AAATATCACTTTCCAGCCTACTTTTTTATCAGTTGGGCTCTCTAAAATTGTTTTGAAATC
+AGGTTGAACATATTTCAGTGTATGACCAATCGAAACATTTGCACCAATAAGGCCGCCAAT
+TTTTCCTGTATCATCACCAGTAACATTACCGTTGAATCCATAAGTTAAAGTACTCATATA
+CTCTTTTGTATCAATCGAATTTCTTGGATAGTAATCAGATATTTGAGCTACTTCATTATC
+AGGTAGTTGCAACTGTACCTTAAAGGCTGAAGGCCAGGCTAAACCACTTTTGTTAGCACC
+TTCTTCGCTATAAACTCTATATTGACCAGCAATGGTACCTTTCGTTCTAATAACTAGCAG
+TTTTTTATTGTGATTTTTATCATCGATAAAACTATAAAATACTTTTTTGTGCATGCCATT
+TTCTTTATCATAAGTGACTAAATCACCTGTTTTTACTGTAGTATTGCTTCCAATATCTGT
+AGTACCGGTTTTAATATTAATATCAGAATCTGCGGCATTAGCGACAGGATTCATTAATAT
+GGAACCTAGCAATAGTGTTGTTGTTACTGAGCTGACTATACGTGTTTTCATTTTCATCAT
+CCTTCTATTTTTTTTAACGATTTGAGGAAACAATAATCAATATGTCAATTTAGAATATTG
+CAGTTGAGACATATCAAATATTTATAATCGTTTATATTAGTATATTTAATGTAGCAACTG
+ATAAATTACTGAGTGATGATGAGTGATTATTTTAAGAATATGTTTTTAACTTTTATTTAA
+AATTTGAAAGGAAGCATTTCAATTTCGAGGGTTAGTCAAAGTTGAATAAATTCTTTATGA
+AACAAGGAAAAGACATAGCTAATTTTATTGATTAATTTCTTTAAAACTAATGATTTGTTT
+GATTTAAAAATGTAATCGATTACAATATAAAAATACAAATATCTTAGAATTAAATCAATT
+AATTAACTATTAAATAAAAATTAAATATATATTAACTACTGTAAATTAATAAATAGAAAT
+AGAGAAAAAGGGTATTAATTATGTTTGGAATTTCGTCGGGAATAATTTTTGCCATTACAT
+AGAAATATCTAATAGATAATGAAAAAGTATCGTATGTATTTTTAATATAGTGTAAAATAT
+CATATGTAAAATAAAATGTAGATTTTTAGTTAGAGGCATTATAAGAAAATTTTGAGTATA
+GGTTAGCTTTTAATTATGAATCTTATTGAAATTTGATTAATAAATATATGATAGGGGATT
+AAAATGAAACTATTTTATATCGTATTTCTTATTATTATATGGCTGAATATATTTTTAGGA
+AATGAAATTATCCATACACTGACTGTTTTAATAACAACATTGTATATTGTTAATTCAAGA
+AAGGGGATTAAAAATGACAGAGTTGAATAATATTATAAACTCTCTTCAATCTTTGTTTGA
+GTCTGAATCAGGCTATAAAATTTCGAAAAATTCAGGAGTTCCATATCAAACAGTACAAGA
+TTTAAGAAATGGGAAAACCAAACTAGAAGATGCTAGATTTAGAACGATTATTAAACTTTA
+TAGTTACTATGTCTCATTAAAAGAACATTAATCATGGGACAATAAAGTATTGCTATAATA
+ATTGAATCATTAAATGAAGGAATAGAGCCTAAGACATAATAAATCAATGTCTTAGGCTCT
+ACAATATTATATTGGTAGTAGTTGACCGAATGAAAATGACCATGTAACAAGCATTTTTGG
+GGCCCCAACACAGAAGCTGACGAAAAGTCAGCTTACAATAATGTGCAAGTTGGGGATGGG
+CCCCAACACAGAGAATTTCAAAAAGAAATTCTACAGACAATGCAAGTTGGCGGGGCCCCA
+ACATAGAGAAATTCAAAAAGAAATTCTACAGACAATGCAAGTTGGGGAGTGACAACGAAA
+TAAATTTTATAAAATACCATTTCTGTCACATTCCTACTCCCAATTCCATTTAAATATATA
+GAAAATTTCACCTATTATATACATCATACACTTTAAAAATTATCATTTAAATAATCTGAT
+TTGGAATTAAAGTGCATGAAGTATAAGTCACCTTCATATACTAATCAAAGAGGACGTCAA
+CAGTTATTTTATTAGGATTTTTAACATAAACATTTGCTAGATCTGAATGTAATCTTTTGC
+TTAAATCAATAGTGTAGTTATTACCGCCACCGGTGATCTTAAGCTTACCTTTATTACGAT
+TTTCGGTATATAATATTTTATTTTTTATTAACGCTTCTCGTGCACGGAAATCGATTTCTT
+TCAATGTTAATACTGGTTTATTGCCTTGGTATATTTTATGCGCACCAATAATCGTTTGTA
+GTTTATCTTTGTATTGCACAAAAAGATTATAAGTTTTATCAGAAGGTTTTGCGGCTGGTG
+TAACGCCACCTGTAAATGTCTCTCTATAAGACCACCATAACTGATCAGTATCTTTGTCTT
+TTAGTCCAAACACATCTACGTAACGATCTTTTAACTGATTAATATTTCCCCAACTTTCAG
+CGCCCCATAAAGATATATGTGCTGACCATGAATATCTCTTAAGTTCAACATAAATGTTTC
+CATTATCATATTGATATAGCCATTTATTTGAAAATGAAAAATGAGGCTGTGTGTAATATT
+TAATTAATTCATTGATGTTAGTTTCATCTTGACCAATGCTATAAGCTTTAGCTTCAGAGT
+AAAAACTAAATACTGGTTTTTGATTTTGAGGTAATACAGTACCTAATAGTAATAATGTTG
+TCGTTAAAATTATATTTTTCGTGATGTTCTTACTCATTAGAACATCTCCTTTCAGAGGAA
+TCATGATACGAGGAATAAGAAATTTAAATGTGAGCGAAGTCAATATAGTATTTGCGATTA
+TTTTTATTAACTCCATTATTATTGTTAGTTTGATTTTTCGAGGATAACTTCAATTTTTGC
+ATTTTGAGGTTTTTTAACATATCTATTTGCATCAGTTGATGGCAACCTTTTACTTAAATC
+TATTGTGTAGTTATTGTCTGTACCTGTTATTTTAATTTGTCCTTTATTATAAGAATTATT
+ATATAATTTTTTACTTTTAATTAATGTTTGACGAATACGAAAATCTAATTCTTTTAAAGT
+TAAAACAGGCTTATTGCCTTCATAAACTGGAAATCCGCCAGTAAACGTTTCTGCTTTATC
+TTTATATGTTACATTCAGTTTATAGTGTTTATCGTTAGATGTTGCTGCAGGAGTAACACC
+ACCAGTAAACGTTTCTTGAGATAATGCAAAAGAATCAATGGTTTCTTGGTCTTTTATGCC
+AAAAATATCAACGCTTTTATTTCTTAATTGGTTGATATTGCCCCAACTTTCAGGTCCATA
+AACTTGAATATGACTATACCAAGAAAACTGTAACAACGTTGCATGAATCGTACCGTTATC
+TTTTTGCCATAACGTACTGTTAGAGAAGGTTAAATATTTTTGCGAGTAATATTTAGTTAA
+CTCATTAACGTTAGTTTCGTTTTGATTTATATAATAAGCTTTCGCTTCAGATGAAGAATT
+GATAGGTGTATTAGGAAATTGTGTAAATGCTGTACCTAATAGTAACAATGTTGTTGATAA
+AATAATTTTTTTCGTGATGTTATTGTTCATTCGAATTTCTCCTTTGAGTATTGTTGGAAT
+GTTTAATTATAAAAAGGGGTTAATTAGATAATTGAAATTATCCGCATTTACAAAAGGTAA
+TAGGTTAGTTAGATTTTTCGAGTATGACTTCAATTTGTGCATTTTTAGGATTTTTAACAT
+AACGGTTTGTGTCAGTTAATTTTAACTTTTTACTTAAATCAATCGTGTAATTATTTCCAT
+CAGCAGTTATCTTAATTTGACCTTTATTAAATTCTCCGTTATATAACTTTTTATTCTTTA
+TTAATGTTTGACGAATACGGAAATCTAATTCTTTTAAAGTTAATACTGGTTTATTTCCTT
+TGTAAAATTCATGTCCACCGATGATAGTTTGTTGTTTATCACTATATTTTAAAAATAGTC
+TATAAGGTTTATCAGATGAAGTAGCTGCTGGCGTAACACCACCAGTAAATGTTTCATCAT
+AAGTCCAGTAACCTTCAACTGTGTCCTCATCTTTAGTTCCAAATATATCAACGTATTTAT
+TTCTTAACTGATTAATGTTTCCCCAACTCTCGGATCCAAACACTTGAATATGACTATACC
+AAACCCACGTTTGCAATGTTGCATGAATGCTACCATTGGGCTTTTGCCATAGCCATTTTC
+CAGATAATGAAAAATGCGGCTGAGTGTAATATTTGATTAACTCATTGATATTAGTCTCGT
+TTTCACTGATATTATAGGCTTTTGCTTCAGATGAAAAACTGATTGGTGTTTTAGGAAGTT
+GTGTTGATGTGGTTCCTAAAAGTAACAATGCTGTTGATAAAACTAATTTATTCATGATGT
+TCTTTTTCATATGAAAATCTCCTTTGCGTGAATTACCCAAAGTATATAAGCTATTACACC
+GATTCGGAATTAAATAAAAGCTAAAACTATGTTAAATAAACTTAAACAGTTAGTAGTGTT
+ATTTAAGCAAAACTTATCATTTTTAAGTTTTGGACAGAAACAGTACTTAATAAAGTAGGC
+GGGAGTTATATATTAAAAACGACACGTTACAATTATTCTCTAATCAATTGCATTAAATTG
+TTTGATAATTGAATTTTCTAACTACTTGAAAAATAGTTATACTTTAAATGTAGTACTTAT
+TTTAATTATTTCCTACTACTTAAATTTAATATTAATAAAATGTTCATTTAATTATTGATA
+AAATATTACAAATTTTAATAGTAGGTTGTGTTTATTTTGTATGCGCTTACAATTTAGGTG
+TAACTAAAATAAAAGGAGTTGTTATTAATGAAAAATTTACGAAACAGAAGTTTTTTAACT
+TTATTAGACTTTTCACGACAAGAGGTAGAATTCTTATTAACACTCTCCGAGGATTTAAAA
+CGTGCTAAATATATTGGCACTGAAAAGCCTATGTTAAAAAATAAAAATATTGCACTGTTA
+TTTGAAAAAGATTCTACAAGAACGCGATGTGCATTTGAAGTTGCAGCGCATGATCAAGGT
+GCAAATGTAACTTATTTAGGCCCAACTGGATCACAAATGGGTAAAAAAGAAACAACTAAA
+GATACTGCACGTGTGCTTGGTGGAATGTATGATGGCATTGAATACCGTGGTTTTTCACAA
+AGAACAGTAGAAACTTTAGCTGAAAATTCAGGCGTACCAGTGTGGAATGGTTTAACTGAT
+GAAGATCATCCTACTCAAGTTCTTGCTGATTTCTTAACAGCAAAAGAAGTCTTAAAAAAA
+GATTATGCAGATATTAACTTTACATATGTTGGAGATGGTCGTAATAACGTTGCAAATGCA
+TTAATGCAAGGTGCTGCCATTATGGGTATGAACTTCCATTTAGTTTGTCCAAAAGAATTA
+AATCCAACAGATGAATTATTAAATCGCTGTAAAAATATTGCCGCTGAAAATGGTGGCAAC
+ATATTAATCACAGATGATATTGACCAAGGTGTAAAAGGTTCGGATGTAATTTACACTGAT
+GTTTGGGTATCAATGGGTGAACCTGATGAAGTATGGAAAGAACGACTTGAATTATTGAAA
+CCATATCAAGTAAATAAAGAAATGATGGATAAAACTGGTAATCCAAATGTTATTTTTGAG
+CATTGCTTACCATCTTTCCATAATGCTGATACGAAAATTGGTCAACAAATTTTTGAAAAA
+TATGGTATTCGAGAAATGGAAGTTACAGATGAAGTATTCGAAAGTAAAGCTTCAGTTGTA
+TTCCAAGAAGCTGAGAACAGAATGCATACAATCAAAGCAGTCATGGTTGCTACATTGGGT
+GAATTTTAAATGATATAAGGAAGTGAATATGATGGCGAAAATAGTAGTAGCATTAGGTGG
+TAATGCTTTAGGAAAATCACCTCAAGAACAACTCGAGCTTGTTAAAAATACTGCGAAATC
+ATTAGTAGGATTAATAACAAAAGGACATGAGATTGTTATTAGTCATGGTAATGGACCACA
+GGTTGGAAGCATTAATTTGGGACTTAACTATGCTGCAGAACATAACCAAGGTCCGGCATT
+TCCATTTGCTGAATGTGGCGCAATGAGTCAAGCTTACATCGGCTATCAATTACAAGAAAG
+CTTACAAAATGAATTGCATTCTATTGGAATGGATAAACAAGTGGTAACACTAGTGACACA
+AGTTGAAGTTGATGAAAATGATCCGGCATTTAACAATCCTTCAAAACCAATTGGGTTATT
+TTACAACAAAGAAGAAGCTGAACAAATTCAAAAAGAAAAAGGATTTATATTTGTTGAAGA
+TGCTGGAAGAGGATATAGACGCGTTGTTCCTTCACCACAACCCATCTCTATTATTGAATT
+AGAGAGTATTAAAACACTTATTAAAAATGATACACTCGTTATTGCTGCTGGTGGTGGAGG
+TATACCAGTAATTAGAGAGCAACATGATGGTTTTAAAGGTATTGATGCAGTTATAGACAA
+AGATAAAACAAGTGCGTTGTTGGGTGCTAATATTCAATGCGATCAATTGATTATTTTAAC
+AGCAATTGATTATGTATATATTAATTTTAACACTGAAAACCAACAGCCTTTGAAAACAAC
+AAATGTTGATGAATTAAAACGATATATAGACGAAAATCAATTTGCAAAAGGAAGTATGTT
+ACCAAAAATTGAAGCAGCCATATCATTTATTGAAAACAATCCAAAAGGAAGTGTGCTTAT
+AACATCATTAAATGAATTAGATGCTGCCTTAGAGGGTAAAGTAGGTACTGTGATTAAAAA
+GTAATTGAATTGAAACGCTTTTCAATTACTATATGTCAAATGCATGATTTTTATTATTTA
+TGTGCACCCCCTGAAAATAATGCCTCTATTTTGATGCGGGGTGCACTTTCTTAATTTATA
+TTTATAAAATCTTTAAGGTAGAAATGCTAGGTTAAATGTCGAAGGAGATGAAACCGTGGA
+AAATACAATTAATGAAAGTGAAAAGAAAAAACGATTTAAATTAAAAATGCCAGGTGCATT
+TATGATTTTATTCATTTTAACGGTTGTTGCAGTTATAGCAACATGGGTTATTCCTGCTGG
+TGCATATTCTAAACTTTCTTACGAACCTTCATCCCAAGAACTAAAGATAGTTAACCCTCA
+TAACCAAGTGAAAAAGGTTCCGGGTACGCAACAGGAACTAGACAAAATGGGGGTTAAAAT
+TAAGATTGAACAATTTAAATCAGGTGCAATTAATAAGCCAGTATCAATTCCGAATACTTA
+TGAAAGATTAAAGCAACATCCAGCTGGACCAGAACAAATAACAAGTAGCATGGTTGAAGG
+TACGATAGAAGCGGTCGATATCATGGTATTCATTCTTGTACTAGGGGGACTTATTGGCGT
+AGTTCAAGCCAGTGGTTCTTTTGAATCGGGATTGTTAGCTTTAACGAAGAAAACAAAAGG
+GCATGAATTTATGCTAATTGTGTTTGTATCAATACTAATGATTATCGGCGGGACGTTATG
+TGGTATTGAAGAAGAAGCTGTAGCATTCTATCCGATTTTAGTCCCTATATTTATAGCGTT
+AGGATACGATTCTATCGTTTCAGTTGGTGCCATATTCCTTGCCAGCTCTGTCGGTAGTAC
+ATTTTCAACTATTAACCCGTTCTCGGTTGTAATTGCCTCTAATGCCGCTGGTACAACTTT
+TACGGATGGCTTGTATTGGAGAATAGGTGCTTGTATTGTCGGTGCGATTTTTGTTATTAG
+TTATTTATATTGGTACTGTAAAAAAATTAAAAACGATCCTAAAGCGTCATATTCTTATGA
+AGACAAAGATGCTTTTGAACAGCAATGGTCTGTATTAAAAGATGACGATAGTGCCCATTT
+TACTTTGCGTAAGAAGATAATCCTTACATTATTTGTACTACCATTTCCAATTATGGTATG
+GGGAGTTATGACGCAAGGTTGGTGGTTCCCAGTTATGGCTTCAGCATTTTTAATATTTAC
+AATTATAATAATGTTTATTGCTGGGACAGGTAAATCTGGATTGGGAGAAAAAGGAACTGT
+AGATGCATTTGTCAATGGTGCATCAAGTTTAGTAGGTGTATCTTTAATTATTGGTTTAGC
+TCGAGGTATTAATTTAGTGTTGAATGAAGGTATGATTTCAGATACAATCTTACACTTTTC
+ATCATCTTTAGTTCAACATATGAGTGGACCATTATTTATCATCGTATTACTATTTATTTT
+CTTCTGTTTAGGTTTTATCGTGCCATCATCTTCTGGATTAGCGGTATTATCAATGCCTAT
+CTTTGCACCACTAGCTGATACAGTAGGTATACCAAGATTCGTCATCGTTACGACATATCA
+ATTTGGTCAATATGCGATGTTATTCTTAGCGCCGACTGGACTTGTTATGGCCACACTACA
+AATGTTAAACATGCGATATTCACATTGGTTCCGATTTGTATGGCCGGTAGTTGCTTTTGT
+ATTGATTTTCGGTGGCGGAGTACTAATTACGCAAGTACTAATTTATTCATAATTTGAAAT
+GCTATATTATAAAAATACTAATTGGGTTTTATGCATCTCGTAGGTTTGTAGAAATACTAA
+ACTAAGCGAGGTGCATTATTATTTTTGATTAAGAAAATAATGACGGTAATGATAACACTA
+GTAAGTAATTGATACAATGCTCTATTTAATAATGATATTTTTAAAATTTGTTTTTAATGT
+AATGTTAGATCTATGGTATATTATATTTATCGTGGTAAATATGTATTTGCTGTAAACAGT
+TTTTGTAACACATGACACATATGGTTGTGAAAATAGCATATATAAAGGATGGCTATAAAT
+GACACATTTGACAAAGGTTTTAGATACACTAACTGGAATATGCGTAGTATTATTATTTAG
+TAAATATTTTGTGGCGTATGCAAATATGGTGTTTGATTGGAATTTAAGATGGTATTTGCT
+AGAAAACATACCACATTTGCCAATTATATTATTTATTCTGATGTTTATTTTCGGAGTACC
+TTCTGAAATGATAAAAGATAGGCAAAGGAAAAATAACGGTGTTTAATTTATCGATATTTA
+GAGGTGATAAAATTTGTCAACTATTACAAAGACTAAAATAAAAATCTTTATTAATTATTT
+TATTGGTATATTAGCCTTGGCGTTTGCTGCTTATATATTATTTAAATAAAGGTTAGAGTG
+AAACGTGTTTATGAACTAGACGTTCTAGTATAGTTACTACAGCTTTAGTCAGAAGGTATC
+ATTGATAAGATCATATTAAATCAAAGAGGCATTGATATACACTAAAAAGAGGCAAGATTA
+CCTGCCTCTTTTTTAGTTATTAAATATGCGTGTTAATTCTTGGTAATAGTGTTACTGAGA
+CGCATTACGAAGAAATTTATCTTGATTTTCCTTTTTTAAAAAGAAGTGAAGATATCCTAT
+AAAGACTCTAAGTACTATTACAGTGGCTAATAACACTTCGATAAACAAAAGACCTTTCCA
+AATATCTGGAAACATAAGTACAGGCAAACTGTTCTTTAAAGCAGTTGCTGAGATTACTAA
+AGGGAATGTGAAAGCTGAAAATACGGGCGAAAAAGGTTCTTTTAGTAATTTAGGCAATTG
+TATAATGATATAAAAATAAAATATTTGAGCTAATATTAAAAATATAATTACGATAAAAGC
+ATTCGCCTTAGGAAAGGCTATAACATATGCTGCAGCGACTAAAGAAAATGGTGCACAAAT
+TGTCGATGTGTTCGGTTTGATTGACGTCTGCAATGGAAATGCTTTTAATCGCTTGAAAAC
+AATAGGTAAGACAATACAAGTAGCTACAAAGCCATATATTACTGTTAATTGACCTATGAA
+AAAACATCCGCTAACGGGTGCCGTCAATCCTGCGATAGCAATACCAATAAAAAGTACAGT
+CCACGAAGGATAAACATTTTCAAGTGAAAAATCTTTTAAATATTTTATTGAAAAAATAAT
+CATATGCGTCATAATTCCCACAAGGCATAAAATCCAAATAGGCGTTATTAAGCTATTGAT
+AAAAGTTATGTTACTAAAAAATGTATTTAAATAAGTAGTACCTAAAAAGCCAGACATGAA
+AAATGTTGTGAACACTGATGAAACTAGAGGACTGTTTAATTGTTCTTTCACATTATTAAA
+ATATTTGATCATAGTACATAAAAGGTGAATCCAAATCAAGAAAGCAAAGATTCCGCAAAC
+AGCGTTTAAAGTAAGAGATAAGTCTTTTAATAGATTACCCAGGCCTAATAATCCTAAGAC
+TAGTCCTGACGTTACTAGAGGTGCTTTTTGAAGTCTCATGATTTACAACCTTTCTTATGT
+GATTTTCTTCACTAATTATATCATGATAGCTATGGCCAATTAATAAGAAGAGTGTGTACT
+ATTACGTTATTAGAGTATGTATATTGGATTGATAGACACATAATTGACATTTAAATCTCA
+AAATTAATGATATTTGAGGTATGCTTTGCAACCTAAATATTGGAATATGTGGAAAAGTAA
+TTATTTAATTTAAATGATGATTGAAGATTTACAAGGGGGTGTACAAAATGAGAAATCAAA
+TTCAAAAACTATTAGACAGTGATTTGAGCAGTTTACATATATCGAAACAAACAGGAGTTC
+CACAAAGCACAATACACAGAATGAGAAAAAAAGAAAGATCATTAGACAATATGTCATTGA
+AAAACGCTGAACTACTTTATAAATTTGCCAATAGTATATTTAGCAATGAAAATTAAGAAG
+AATAATTAGTGAGTTAAATAATTAAAAAACCACGTCTCGATGGACGTGGTTATTTTTTTA
+AATGTATTTAATTATAGGATTTCGGGCCCCTGAAAAGTCCCTAAAATTTTGAATAGTATC
+AAAATCTATAGGAATAATATAATAATAAAAATCTCTACGCATGCAAATGGTGAGTGTTAA
+AAATCTTGGTGTAGTGTTGGTGTAGTTCAGGTGCAGTATAGATGAAATTTGAGCACAAAA
+TTACTTAATTAAAAATGTATAAACAAGTGTCAGACGCGTGTCAATTGTGTGTCAAAAAAT
+TCTATGACGAATAAGCATGCTTGTTTTAATTACTGTATTTTCGGGGCTTATGCGGGGGAC
+GTTTTGGTGACGCATCATACTATATTACTGAAATTCAAAACAAAAAGAGCCCCGTAATCA
+CGGAACTCTTTTGTTTGGTAATGCGTATAAAAATACCTATAAACGTCCTGGGAGGGATTC
+GAACCCCCGACCGATGGCTTAGAAGGCCATTGCTCTATCCAGCTGAGCTACCAGGACACG
+TTTAACAACACAAGAATTATTATATCTAAATGAACTTAAATTAGCAATACCTTGTAAATA
+AAAAATGTTTATATTTTTCACTATTATAGAGCTATTTATCTAAAAAGGTTCAATAAGACT
+TAAATGCGAATTCAGGCAACTTAATTGTGTTAAATACAGTTTTGAATGCCTAACTGTATT
+TCTTTTCTCTTTAAAATACAGTTAAGTACATTATAAGATGTTGTGCGGATAAACAAACTA
+ATTGCATCAAATTTATTTTAAAATAACAACAACAAAACGTTAAGCGAATAACATTTCGGT
+GATTTAAAAGCTACGCACGTTTTTGTTATCTTCAAATTTAAATTTTAAGGAGTGTTTTCA
+ATGGAAGGTTTATTTAACGCAATTAAAGATACCGTAACTGCAGCAATTAATAATGATGGC
+GCAAAATTAGGCACAAGCATTGTGAGCATCGTTGAAAATGGCGTAGGTTTATTAGGTAAA
+TTATTCGGATTCTAATTTCAATATGTTATGTAAGTAATCAGTATTATTTCAAAGGTGAGG
+GAGAGATTTAAATGACTGGACTAGCAGAAGCAATCGCAAATACTGTGCAAGCTGCACAAC
+AACATGATAGTGTGAAATTAGGCACAAGTATCGTAGACATCGTTGCTAACGGTGTGGGTT
+TACTAGGTAAATTATTTGGATTCTAATATAATAACTAATATTCTTTAAAATAAACTGGGT
+GAGCATACTTTAATGTTATGCACTCAGTTTATTTTATTTGCAGAAATTTGAGCCTCTGTT
+AAGATTTAGATACATAGACAATATAGGAGATGGGGAAATTGGGATATAAAAATATTTTGA
+TAGACTTTGATGATACAATTGTTGATTTTTATGATGCAGAAGAATGGGCGTTTCACTATA
+TGGCGAATGTTTTTAATCATAAAGCAACAAAGGATGATTTTTTAACATTTAAAAAAATCA
+ATCACCAACATTGGGAAGCTTTTCAACAAAATAAATTAACGAAGTCTGAAGTATTATCAG
+AACGATTTGTGAATTACTTCAAACATCATCAAATGGAAGTTGATGGGCATCGTGCAGATG
+TGTTATTTAGAAATGGATTAGCAGAAGCTAAAGTTAAATACTTTGATCAAACATTAGAAA
+CAATTGTCGAATTATCGAAAAGACATGATTTATATATTGTTACTAATGGTGTAACCGAAA
+CGCAAAAGAGAAGGTTAAATCAGACGCCGTTGCATAAATATATTAAAAAGATATTTATAT
+CTGAGGAAACAGGATATCAAAAACCTAATCCGGAATTTTTTAATTATGTTTTTAATGATA
+TTGGTGAGGATGAAAGACAGCACTCGATTATAGTTGGAGATTCTTTAACATCTGACATTC
+TAGGTGGAATCAATGCGGGTATAGCTACTTGCTGGTTTAATTTTAGAGGATTTGATCATA
+ATCCAGGAATTATACCTGATTATGAAATTAATTCATGGAAACAACTAAATGATATTGTAC
+GTTAAGACAAATAATTTGAAAATGATTTATATTAGCTTAAGAAAGTAATTGTAAAAACGA
+CACTACGAAAAGATGCATTTTCATGCTCGTAGTGTCGAATATTATTATCTTATGGTTTCC
+ACAATAAGACATCATGTCCCTCTATATTTTTAGCTTCCACATCTGTAAATCCATGATGTA
+AAAAGAAATCCTTAGAATCATTTCTGCCAATGGCTTTAATTGGCATATTGAAACTCTTTG
+CAAAATCAATCAATTCTGAAGCGTACCCTCTGTTTTGATATTTTGGTAATACTTCTAACT
+TCCATAATAATATATAATCTTCAAAATCTGGGAAGTAGATTTCTTCGACATCACCTTTTT
+TTAGTAATGCCATTCTAGCTCCTAATTGATCTCCGACAAATATGCCATAAAATGGTGAAT
+CTGAACTTGCATCAATCATTTGACCGTTTAACTCATTGACCATGTATAAGTCTTTGTTGC
+CAAACGCTCTAAAGTTTTCGAATAATTCGTCAGTTTTGTAATTAATTTCAAGACGTTTGA
+TTTCACTCATATTTATCTACCCCTTATTTGTTTACTACTATTATTATACATTAAACCACT
+TGTGTTTTTCATTGATTTGAAAATGTAAAACAATGAACATTATAAATTTTCCATGATTAA
+ATTGATTTTCAAGCCGTAAAATTGTCAATCACCGGTATAGACTTTATACTATAGTTTGTA
+ATCGCGTACTTAAGGAGAAAAAACATGGACTGTAAAGTAGTTAGTTTAAATGAAAAAGAT
+CAGTTTATACCAAAAATAAAGAGCAGTGACCCTGTAATAACAGGATTATTTCAATATGAT
+GCAGCTCAACAAACTAGTTTTGAAAAAAGGATGTCTAAAGAAAATAATGGAAGAGAAGCG
+GCATTAGCGAATGTTATTCGTGAATATATGAGTGATTTAAAGCTTTCAAATGAACAAGAA
+TTAAACATACAACATTTAGCTAATGGTTCAAAAGTTGTGATTGGTGGACAACAAGCAGGG
+CTTTTCGGGGGACCATTGTATACATTCCATAAAATATTTTCAATCATTACTTTATCTAAG
+GAATTAACGGATACACATAAGCAACAAGTAGTACCAGTTTTTTGGATTGCAGGAGAAGAT
+CATGATTTCGATGAAGTGAATCATACATTTGTTTATAACGAAAATCATGGGTCGCTGCAT
+AAGGTTAAATATCATACAATGGAGATGCCAGAGACGACAGTCTCTAGATATTATCCTGAT
+AAGGCTGAGTTGAAACAAACTTTAAAAACGATGTTCATTCATATGAAAGAAACTGTTCAT
+ACACAAGGTCTACTGGAGATTTGTGACAGAATTATTGACCAATATGACTCGTGGACTGAT
+ATGTTTAAAGCACTACTGCATGAAACATTTAAAGCATATGGCGTTCTATTTATAGATGCG
+CAGTTTGAGCCGTTAAGAAAAATGGAAGCGCCTATGTTTAAAAAGATTTTGAAAAAACAT
+CAGTTGCTTGATGATGCTTTTAGAGCAACACAACAACGTACTCAAAATCAAGGCTTGAAT
+GCGATGATACAAACAGATACAAATGTTCATTTATTCTTACATGATGAAAATATGCGCCAA
+TTAGTTTCGTATGATGGTAAGCATTTTAAATTAAATAAAACAGATAAGACATATATAAAG
\ No newline at end of file
diff --git a/t/data/query_4_missing_genes.fa b/t/data/query_4_missing_genes.fa
new file mode 100644
index 0000000..0606cb2
--- /dev/null
+++ b/t/data/query_4_missing_genes.fa
@@ -0,0 +1,2 @@
+>4_1
+AAA
\ No newline at end of file
diff --git a/t/data/query_4_missing_genes.gff b/t/data/query_4_missing_genes.gff
new file mode 100644
index 0000000..318d94b
--- /dev/null
+++ b/t/data/query_4_missing_genes.gff
@@ -0,0 +1,256 @@
+##gff-version 3
+##sequence-region abc|SC|contig000001 1 15000
+abc|SC|contig000001 Prodigal:2.60 CDS 172 1131 . - 0 ID=4_1;gene=hly;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:Q2G1X0,protein motif:TIGRFAMs:TIGR01002,protein motif:Pfam:PF07968.6;locus_tag=abc_00001;product=Alpha-toxin,beta-channel forming cytolysin,Leukocidin/Hemolysin toxin family protein;protein_id=gnl|SC|abc_00001
+##FASTA
+>abc|SC|contig000001
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
+ATACCCACCACATTTGGTGGAGAACCAAAAATTAGCCGAAAAACATCATTTCTGAAGTTA
+TCGGCTAAAGTTATAAATTATATTTATTTGTACATGAACAAATAATTTACATTAATTTGT
+CATTTCTTCTTTTTCCCAATCGATTTTATATCTTTCTGAAGAACGATCTGTCCATTTATC
+TTTAGTATTGGTACCTTTCCAATTTGTTGAAGTCCAATGCAATTGGTAGTCATCACGAAC
+TCGTTCGTATATTACATCTATATTTGTTTGTTGTTTGGATGCTTTTCTATCCATAGTAAT
+AACTGTAGCGAAGTCTGGTGAAAACCCTGAAGATAATAGAGAACTTGCTTTGTTAGGATC
+AAGGAAGTTCTCTGCTGCTTTCATAGAACCATTTCTAGTTTTCATGAAAAGTTGATTGCC
+ATATACCGGGTTCCAAGAATCTCTATCATATGGTCCCCAATTTTGATTCACCATATTGTT
+AAATATCACTTTCCAGCCTACTTTTTTATCAGTTGGGCTCTCTAAAATTGTTTTGAAATC
+AGGTTGAACATATTTCAGTGTATGACCAATCGAAACATTTGCACCAATAAGGCCGCCAAT
+TTTTCCTGTATCATCACCAGTAACATTACCGTTGAATCCATAAGTTAAAGTACTCATATA
+CTCTTTTGTATCAATCGAATTTCTTGGATAGTAATCAGATATTTGAGCTACTTCATTATC
+AGGTAGTTGCAACTGTACCTTAAAGGCTGAAGGCCAGGCTAAACCACTTTTGTTAGCACC
+TTCTTCGCTATAAACTCTATATTGACCAGCAATGGTACCTTTCGTTCTAATAACTAGCAG
+TTTTTTATTGTGATTTTTATCATCGATAAAACTATAAAATACTTTTTTGTGCATGCCATT
+TTCTTTATCATAAGTGACTAAATCACCTGTTTTTACTGTAGTATTGCTTCCAATATCTGT
+AGTACCGGTTTTAATATTAATATCAGAATCTGCGGCATTAGCGACAGGATTCATTAATAT
+GGAACCTAGCAATAGTGTTGTTGTTACTGAGCTGACTATACGTGTTTTCATTTTCATCAT
+CCTTCTATTTTTTTTAACGATTTGAGGAAACAATAATCAATATGTCAATTTAGAATATTG
+CAGTTGAGACATATCAAATATTTATAATCGTTTATATTAGTATATTTAATGTAGCAACTG
+ATAAATTACTGAGTGATGATGAGTGATTATTTTAAGAATATGTTTTTAACTTTTATTTAA
+AATTTGAAAGGAAGCATTTCAATTTCGAGGGTTAGTCAAAGTTGAATAAATTCTTTATGA
+AACAAGGAAAAGACATAGCTAATTTTATTGATTAATTTCTTTAAAACTAATGATTTGTTT
+GATTTAAAAATGTAATCGATTACAATATAAAAATACAAATATCTTAGAATTAAATCAATT
+AATTAACTATTAAATAAAAATTAAATATATATTAACTACTGTAAATTAATAAATAGAAAT
+AGAGAAAAAGGGTATTAATTATGTTTGGAATTTCGTCGGGAATAATTTTTGCCATTACAT
+AGAAATATCTAATAGATAATGAAAAAGTATCGTATGTATTTTTAATATAGTGTAAAATAT
+CATATGTAAAATAAAATGTAGATTTTTAGTTAGAGGCATTATAAGAAAATTTTGAGTATA
+GGTTAGCTTTTAATTATGAATCTTATTGAAATTTGATTAATAAATATATGATAGGGGATT
+AAAATGAAACTATTTTATATCGTATTTCTTATTATTATATGGCTGAATATATTTTTAGGA
+AATGAAATTATCCATACACTGACTGTTTTAATAACAACATTGTATATTGTTAATTCAAGA
+AAGGGGATTAAAAATGACAGAGTTGAATAATATTATAAACTCTCTTCAATCTTTGTTTGA
+GTCTGAATCAGGCTATAAAATTTCGAAAAATTCAGGAGTTCCATATCAAACAGTACAAGA
+TTTAAGAAATGGGAAAACCAAACTAGAAGATGCTAGATTTAGAACGATTATTAAACTTTA
+TAGTTACTATGTCTCATTAAAAGAACATTAATCATGGGACAATAAAGTATTGCTATAATA
+ATTGAATCATTAAATGAAGGAATAGAGCCTAAGACATAATAAATCAATGTCTTAGGCTCT
+ACAATATTATATTGGTAGTAGTTGACCGAATGAAAATGACCATGTAACAAGCATTTTTGG
+GGCCCCAACACAGAAGCTGACGAAAAGTCAGCTTACAATAATGTGCAAGTTGGGGATGGG
+CCCCAACACAGAGAATTTCAAAAAGAAATTCTACAGACAATGCAAGTTGGCGGGGCCCCA
+ACATAGAGAAATTCAAAAAGAAATTCTACAGACAATGCAAGTTGGGGAGTGACAACGAAA
+TAAATTTTATAAAATACCATTTCTGTCACATTCCTACTCCCAATTCCATTTAAATATATA
+GAAAATTTCACCTATTATATACATCATACACTTTAAAAATTATCATTTAAATAATCTGAT
+TTGGAATTAAAGTGCATGAAGTATAAGTCACCTTCATATACTAATCAAAGAGGACGTCAA
+CAGTTATTTTATTAGGATTTTTAACATAAACATTTGCTAGATCTGAATGTAATCTTTTGC
+TTAAATCAATAGTGTAGTTATTACCGCCACCGGTGATCTTAAGCTTACCTTTATTACGAT
+TTTCGGTATATAATATTTTATTTTTTATTAACGCTTCTCGTGCACGGAAATCGATTTCTT
+TCAATGTTAATACTGGTTTATTGCCTTGGTATATTTTATGCGCACCAATAATCGTTTGTA
+GTTTATCTTTGTATTGCACAAAAAGATTATAAGTTTTATCAGAAGGTTTTGCGGCTGGTG
+TAACGCCACCTGTAAATGTCTCTCTATAAGACCACCATAACTGATCAGTATCTTTGTCTT
+TTAGTCCAAACACATCTACGTAACGATCTTTTAACTGATTAATATTTCCCCAACTTTCAG
+CGCCCCATAAAGATATATGTGCTGACCATGAATATCTCTTAAGTTCAACATAAATGTTTC
+CATTATCATATTGATATAGCCATTTATTTGAAAATGAAAAATGAGGCTGTGTGTAATATT
+TAATTAATTCATTGATGTTAGTTTCATCTTGACCAATGCTATAAGCTTTAGCTTCAGAGT
+AAAAACTAAATACTGGTTTTTGATTTTGAGGTAATACAGTACCTAATAGTAATAATGTTG
+TCGTTAAAATTATATTTTTCGTGATGTTCTTACTCATTAGAACATCTCCTTTCAGAGGAA
+TCATGATACGAGGAATAAGAAATTTAAATGTGAGCGAAGTCAATATAGTATTTGCGATTA
+TTTTTATTAACTCCATTATTATTGTTAGTTTGATTTTTCGAGGATAACTTCAATTTTTGC
+ATTTTGAGGTTTTTTAACATATCTATTTGCATCAGTTGATGGCAACCTTTTACTTAAATC
+TATTGTGTAGTTATTGTCTGTACCTGTTATTTTAATTTGTCCTTTATTATAAGAATTATT
+ATATAATTTTTTACTTTTAATTAATGTTTGACGAATACGAAAATCTAATTCTTTTAAAGT
+TAAAACAGGCTTATTGCCTTCATAAACTGGAAATCCGCCAGTAAACGTTTCTGCTTTATC
+TTTATATGTTACATTCAGTTTATAGTGTTTATCGTTAGATGTTGCTGCAGGAGTAACACC
+ACCAGTAAACGTTTCTTGAGATAATGCAAAAGAATCAATGGTTTCTTGGTCTTTTATGCC
+AAAAATATCAACGCTTTTATTTCTTAATTGGTTGATATTGCCCCAACTTTCAGGTCCATA
+AACTTGAATATGACTATACCAAGAAAACTGTAACAACGTTGCATGAATCGTACCGTTATC
+TTTTTGCCATAACGTACTGTTAGAGAAGGTTAAATATTTTTGCGAGTAATATTTAGTTAA
+CTCATTAACGTTAGTTTCGTTTTGATTTATATAATAAGCTTTCGCTTCAGATGAAGAATT
+GATAGGTGTATTAGGAAATTGTGTAAATGCTGTACCTAATAGTAACAATGTTGTTGATAA
+AATAATTTTTTTCGTGATGTTATTGTTCATTCGAATTTCTCCTTTGAGTATTGTTGGAAT
+GTTTAATTATAAAAAGGGGTTAATTAGATAATTGAAATTATCCGCATTTACAAAAGGTAA
+TAGGTTAGTTAGATTTTTCGAGTATGACTTCAATTTGTGCATTTTTAGGATTTTTAACAT
+AACGGTTTGTGTCAGTTAATTTTAACTTTTTACTTAAATCAATCGTGTAATTATTTCCAT
+CAGCAGTTATCTTAATTTGACCTTTATTAAATTCTCCGTTATATAACTTTTTATTCTTTA
+TTAATGTTTGACGAATACGGAAATCTAATTCTTTTAAAGTTAATACTGGTTTATTTCCTT
+TGTAAAATTCATGTCCACCGATGATAGTTTGTTGTTTATCACTATATTTTAAAAATAGTC
+TATAAGGTTTATCAGATGAAGTAGCTGCTGGCGTAACACCACCAGTAAATGTTTCATCAT
+AAGTCCAGTAACCTTCAACTGTGTCCTCATCTTTAGTTCCAAATATATCAACGTATTTAT
+TTCTTAACTGATTAATGTTTCCCCAACTCTCGGATCCAAACACTTGAATATGACTATACC
+AAACCCACGTTTGCAATGTTGCATGAATGCTACCATTGGGCTTTTGCCATAGCCATTTTC
+CAGATAATGAAAAATGCGGCTGAGTGTAATATTTGATTAACTCATTGATATTAGTCTCGT
+TTTCACTGATATTATAGGCTTTTGCTTCAGATGAAAAACTGATTGGTGTTTTAGGAAGTT
+GTGTTGATGTGGTTCCTAAAAGTAACAATGCTGTTGATAAAACTAATTTATTCATGATGT
+TCTTTTTCATATGAAAATCTCCTTTGCGTGAATTACCCAAAGTATATAAGCTATTACACC
+GATTCGGAATTAAATAAAAGCTAAAACTATGTTAAATAAACTTAAACAGTTAGTAGTGTT
+ATTTAAGCAAAACTTATCATTTTTAAGTTTTGGACAGAAACAGTACTTAATAAAGTAGGC
+GGGAGTTATATATTAAAAACGACACGTTACAATTATTCTCTAATCAATTGCATTAAATTG
+TTTGATAATTGAATTTTCTAACTACTTGAAAAATAGTTATACTTTAAATGTAGTACTTAT
+TTTAATTATTTCCTACTACTTAAATTTAATATTAATAAAATGTTCATTTAATTATTGATA
+AAATATTACAAATTTTAATAGTAGGTTGTGTTTATTTTGTATGCGCTTACAATTTAGGTG
+TAACTAAAATAAAAGGAGTTGTTATTAATGAAAAATTTACGAAACAGAAGTTTTTTAACT
+TTATTAGACTTTTCACGACAAGAGGTAGAATTCTTATTAACACTCTCCGAGGATTTAAAA
+CGTGCTAAATATATTGGCACTGAAAAGCCTATGTTAAAAAATAAAAATATTGCACTGTTA
+TTTGAAAAAGATTCTACAAGAACGCGATGTGCATTTGAAGTTGCAGCGCATGATCAAGGT
+GCAAATGTAACTTATTTAGGCCCAACTGGATCACAAATGGGTAAAAAAGAAACAACTAAA
+GATACTGCACGTGTGCTTGGTGGAATGTATGATGGCATTGAATACCGTGGTTTTTCACAA
+AGAACAGTAGAAACTTTAGCTGAAAATTCAGGCGTACCAGTGTGGAATGGTTTAACTGAT
+GAAGATCATCCTACTCAAGTTCTTGCTGATTTCTTAACAGCAAAAGAAGTCTTAAAAAAA
+GATTATGCAGATATTAACTTTACATATGTTGGAGATGGTCGTAATAACGTTGCAAATGCA
+TTAATGCAAGGTGCTGCCATTATGGGTATGAACTTCCATTTAGTTTGTCCAAAAGAATTA
+AATCCAACAGATGAATTATTAAATCGCTGTAAAAATATTGCCGCTGAAAATGGTGGCAAC
+ATATTAATCACAGATGATATTGACCAAGGTGTAAAAGGTTCGGATGTAATTTACACTGAT
+GTTTGGGTATCAATGGGTGAACCTGATGAAGTATGGAAAGAACGACTTGAATTATTGAAA
+CCATATCAAGTAAATAAAGAAATGATGGATAAAACTGGTAATCCAAATGTTATTTTTGAG
+CATTGCTTACCATCTTTCCATAATGCTGATACGAAAATTGGTCAACAAATTTTTGAAAAA
+TATGGTATTCGAGAAATGGAAGTTACAGATGAAGTATTCGAAAGTAAAGCTTCAGTTGTA
+TTCCAAGAAGCTGAGAACAGAATGCATACAATCAAAGCAGTCATGGTTGCTACATTGGGT
+GAATTTTAAATGATATAAGGAAGTGAATATGATGGCGAAAATAGTAGTAGCATTAGGTGG
+TAATGCTTTAGGAAAATCACCTCAAGAACAACTCGAGCTTGTTAAAAATACTGCGAAATC
+ATTAGTAGGATTAATAACAAAAGGACATGAGATTGTTATTAGTCATGGTAATGGACCACA
+GGTTGGAAGCATTAATTTGGGACTTAACTATGCTGCAGAACATAACCAAGGTCCGGCATT
+TCCATTTGCTGAATGTGGCGCAATGAGTCAAGCTTACATCGGCTATCAATTACAAGAAAG
+CTTACAAAATGAATTGCATTCTATTGGAATGGATAAACAAGTGGTAACACTAGTGACACA
+AGTTGAAGTTGATGAAAATGATCCGGCATTTAACAATCCTTCAAAACCAATTGGGTTATT
+TTACAACAAAGAAGAAGCTGAACAAATTCAAAAAGAAAAAGGATTTATATTTGTTGAAGA
+TGCTGGAAGAGGATATAGACGCGTTGTTCCTTCACCACAACCCATCTCTATTATTGAATT
+AGAGAGTATTAAAACACTTATTAAAAATGATACACTCGTTATTGCTGCTGGTGGTGGAGG
+TATACCAGTAATTAGAGAGCAACATGATGGTTTTAAAGGTATTGATGCAGTTATAGACAA
+AGATAAAACAAGTGCGTTGTTGGGTGCTAATATTCAATGCGATCAATTGATTATTTTAAC
+AGCAATTGATTATGTATATATTAATTTTAACACTGAAAACCAACAGCCTTTGAAAACAAC
+AAATGTTGATGAATTAAAACGATATATAGACGAAAATCAATTTGCAAAAGGAAGTATGTT
+ACCAAAAATTGAAGCAGCCATATCATTTATTGAAAACAATCCAAAAGGAAGTGTGCTTAT
+AACATCATTAAATGAATTAGATGCTGCCTTAGAGGGTAAAGTAGGTACTGTGATTAAAAA
+GTAATTGAATTGAAACGCTTTTCAATTACTATATGTCAAATGCATGATTTTTATTATTTA
+TGTGCACCCCCTGAAAATAATGCCTCTATTTTGATGCGGGGTGCACTTTCTTAATTTATA
+TTTATAAAATCTTTAAGGTAGAAATGCTAGGTTAAATGTCGAAGGAGATGAAACCGTGGA
+AAATACAATTAATGAAAGTGAAAAGAAAAAACGATTTAAATTAAAAATGCCAGGTGCATT
+TATGATTTTATTCATTTTAACGGTTGTTGCAGTTATAGCAACATGGGTTATTCCTGCTGG
+TGCATATTCTAAACTTTCTTACGAACCTTCATCCCAAGAACTAAAGATAGTTAACCCTCA
+TAACCAAGTGAAAAAGGTTCCGGGTACGCAACAGGAACTAGACAAAATGGGGGTTAAAAT
+TAAGATTGAACAATTTAAATCAGGTGCAATTAATAAGCCAGTATCAATTCCGAATACTTA
+TGAAAGATTAAAGCAACATCCAGCTGGACCAGAACAAATAACAAGTAGCATGGTTGAAGG
+TACGATAGAAGCGGTCGATATCATGGTATTCATTCTTGTACTAGGGGGACTTATTGGCGT
+AGTTCAAGCCAGTGGTTCTTTTGAATCGGGATTGTTAGCTTTAACGAAGAAAACAAAAGG
+GCATGAATTTATGCTAATTGTGTTTGTATCAATACTAATGATTATCGGCGGGACGTTATG
+TGGTATTGAAGAAGAAGCTGTAGCATTCTATCCGATTTTAGTCCCTATATTTATAGCGTT
+AGGATACGATTCTATCGTTTCAGTTGGTGCCATATTCCTTGCCAGCTCTGTCGGTAGTAC
+ATTTTCAACTATTAACCCGTTCTCGGTTGTAATTGCCTCTAATGCCGCTGGTACAACTTT
+TACGGATGGCTTGTATTGGAGAATAGGTGCTTGTATTGTCGGTGCGATTTTTGTTATTAG
+TTATTTATATTGGTACTGTAAAAAAATTAAAAACGATCCTAAAGCGTCATATTCTTATGA
+AGACAAAGATGCTTTTGAACAGCAATGGTCTGTATTAAAAGATGACGATAGTGCCCATTT
+TACTTTGCGTAAGAAGATAATCCTTACATTATTTGTACTACCATTTCCAATTATGGTATG
+GGGAGTTATGACGCAAGGTTGGTGGTTCCCAGTTATGGCTTCAGCATTTTTAATATTTAC
+AATTATAATAATGTTTATTGCTGGGACAGGTAAATCTGGATTGGGAGAAAAAGGAACTGT
+AGATGCATTTGTCAATGGTGCATCAAGTTTAGTAGGTGTATCTTTAATTATTGGTTTAGC
+TCGAGGTATTAATTTAGTGTTGAATGAAGGTATGATTTCAGATACAATCTTACACTTTTC
+ATCATCTTTAGTTCAACATATGAGTGGACCATTATTTATCATCGTATTACTATTTATTTT
+CTTCTGTTTAGGTTTTATCGTGCCATCATCTTCTGGATTAGCGGTATTATCAATGCCTAT
+CTTTGCACCACTAGCTGATACAGTAGGTATACCAAGATTCGTCATCGTTACGACATATCA
+ATTTGGTCAATATGCGATGTTATTCTTAGCGCCGACTGGACTTGTTATGGCCACACTACA
+AATGTTAAACATGCGATATTCACATTGGTTCCGATTTGTATGGCCGGTAGTTGCTTTTGT
+ATTGATTTTCGGTGGCGGAGTACTAATTACGCAAGTACTAATTTATTCATAATTTGAAAT
+GCTATATTATAAAAATACTAATTGGGTTTTATGCATCTCGTAGGTTTGTAGAAATACTAA
+ACTAAGCGAGGTGCATTATTATTTTTGATTAAGAAAATAATGACGGTAATGATAACACTA
+GTAAGTAATTGATACAATGCTCTATTTAATAATGATATTTTTAAAATTTGTTTTTAATGT
+AATGTTAGATCTATGGTATATTATATTTATCGTGGTAAATATGTATTTGCTGTAAACAGT
+TTTTGTAACACATGACACATATGGTTGTGAAAATAGCATATATAAAGGATGGCTATAAAT
+GACACATTTGACAAAGGTTTTAGATACACTAACTGGAATATGCGTAGTATTATTATTTAG
+TAAATATTTTGTGGCGTATGCAAATATGGTGTTTGATTGGAATTTAAGATGGTATTTGCT
+AGAAAACATACCACATTTGCCAATTATATTATTTATTCTGATGTTTATTTTCGGAGTACC
+TTCTGAAATGATAAAAGATAGGCAAAGGAAAAATAACGGTGTTTAATTTATCGATATTTA
+GAGGTGATAAAATTTGTCAACTATTACAAAGACTAAAATAAAAATCTTTATTAATTATTT
+TATTGGTATATTAGCCTTGGCGTTTGCTGCTTATATATTATTTAAATAAAGGTTAGAGTG
+AAACGTGTTTATGAACTAGACGTTCTAGTATAGTTACTACAGCTTTAGTCAGAAGGTATC
+ATTGATAAGATCATATTAAATCAAAGAGGCATTGATATACACTAAAAAGAGGCAAGATTA
+CCTGCCTCTTTTTTAGTTATTAAATATGCGTGTTAATTCTTGGTAATAGTGTTACTGAGA
+CGCATTACGAAGAAATTTATCTTGATTTTCCTTTTTTAAAAAGAAGTGAAGATATCCTAT
+AAAGACTCTAAGTACTATTACAGTGGCTAATAACACTTCGATAAACAAAAGACCTTTCCA
+AATATCTGGAAACATAAGTACAGGCAAACTGTTCTTTAAAGCAGTTGCTGAGATTACTAA
+AGGGAATGTGAAAGCTGAAAATACGGGCGAAAAAGGTTCTTTTAGTAATTTAGGCAATTG
+TATAATGATATAAAAATAAAATATTTGAGCTAATATTAAAAATATAATTACGATAAAAGC
+ATTCGCCTTAGGAAAGGCTATAACATATGCTGCAGCGACTAAAGAAAATGGTGCACAAAT
+TGTCGATGTGTTCGGTTTGATTGACGTCTGCAATGGAAATGCTTTTAATCGCTTGAAAAC
+AATAGGTAAGACAATACAAGTAGCTACAAAGCCATATATTACTGTTAATTGACCTATGAA
+AAAACATCCGCTAACGGGTGCCGTCAATCCTGCGATAGCAATACCAATAAAAAGTACAGT
+CCACGAAGGATAAACATTTTCAAGTGAAAAATCTTTTAAATATTTTATTGAAAAAATAAT
+CATATGCGTCATAATTCCCACAAGGCATAAAATCCAAATAGGCGTTATTAAGCTATTGAT
+AAAAGTTATGTTACTAAAAAATGTATTTAAATAAGTAGTACCTAAAAAGCCAGACATGAA
+AAATGTTGTGAACACTGATGAAACTAGAGGACTGTTTAATTGTTCTTTCACATTATTAAA
+ATATTTGATCATAGTACATAAAAGGTGAATCCAAATCAAGAAAGCAAAGATTCCGCAAAC
+AGCGTTTAAAGTAAGAGATAAGTCTTTTAATAGATTACCCAGGCCTAATAATCCTAAGAC
+TAGTCCTGACGTTACTAGAGGTGCTTTTTGAAGTCTCATGATTTACAACCTTTCTTATGT
+GATTTTCTTCACTAATTATATCATGATAGCTATGGCCAATTAATAAGAAGAGTGTGTACT
+ATTACGTTATTAGAGTATGTATATTGGATTGATAGACACATAATTGACATTTAAATCTCA
+AAATTAATGATATTTGAGGTATGCTTTGCAACCTAAATATTGGAATATGTGGAAAAGTAA
+TTATTTAATTTAAATGATGATTGAAGATTTACAAGGGGGTGTACAAAATGAGAAATCAAA
+TTCAAAAACTATTAGACAGTGATTTGAGCAGTTTACATATATCGAAACAAACAGGAGTTC
+CACAAAGCACAATACACAGAATGAGAAAAAAAGAAAGATCATTAGACAATATGTCATTGA
+AAAACGCTGAACTACTTTATAAATTTGCCAATAGTATATTTAGCAATGAAAATTAAGAAG
+AATAATTAGTGAGTTAAATAATTAAAAAACCACGTCTCGATGGACGTGGTTATTTTTTTA
+AATGTATTTAATTATAGGATTTCGGGCCCCTGAAAAGTCCCTAAAATTTTGAATAGTATC
+AAAATCTATAGGAATAATATAATAATAAAAATCTCTACGCATGCAAATGGTGAGTGTTAA
+AAATCTTGGTGTAGTGTTGGTGTAGTTCAGGTGCAGTATAGATGAAATTTGAGCACAAAA
+TTACTTAATTAAAAATGTATAAACAAGTGTCAGACGCGTGTCAATTGTGTGTCAAAAAAT
+TCTATGACGAATAAGCATGCTTGTTTTAATTACTGTATTTTCGGGGCTTATGCGGGGGAC
+GTTTTGGTGACGCATCATACTATATTACTGAAATTCAAAACAAAAAGAGCCCCGTAATCA
+CGGAACTCTTTTGTTTGGTAATGCGTATAAAAATACCTATAAACGTCCTGGGAGGGATTC
+GAACCCCCGACCGATGGCTTAGAAGGCCATTGCTCTATCCAGCTGAGCTACCAGGACACG
+TTTAACAACACAAGAATTATTATATCTAAATGAACTTAAATTAGCAATACCTTGTAAATA
+AAAAATGTTTATATTTTTCACTATTATAGAGCTATTTATCTAAAAAGGTTCAATAAGACT
+TAAATGCGAATTCAGGCAACTTAATTGTGTTAAATACAGTTTTGAATGCCTAACTGTATT
+TCTTTTCTCTTTAAAATACAGTTAAGTACATTATAAGATGTTGTGCGGATAAACAAACTA
+ATTGCATCAAATTTATTTTAAAATAACAACAACAAAACGTTAAGCGAATAACATTTCGGT
+GATTTAAAAGCTACGCACGTTTTTGTTATCTTCAAATTTAAATTTTAAGGAGTGTTTTCA
+ATGGAAGGTTTATTTAACGCAATTAAAGATACCGTAACTGCAGCAATTAATAATGATGGC
+GCAAAATTAGGCACAAGCATTGTGAGCATCGTTGAAAATGGCGTAGGTTTATTAGGTAAA
+TTATTCGGATTCTAATTTCAATATGTTATGTAAGTAATCAGTATTATTTCAAAGGTGAGG
+GAGAGATTTAAATGACTGGACTAGCAGAAGCAATCGCAAATACTGTGCAAGCTGCACAAC
+AACATGATAGTGTGAAATTAGGCACAAGTATCGTAGACATCGTTGCTAACGGTGTGGGTT
+TACTAGGTAAATTATTTGGATTCTAATATAATAACTAATATTCTTTAAAATAAACTGGGT
+GAGCATACTTTAATGTTATGCACTCAGTTTATTTTATTTGCAGAAATTTGAGCCTCTGTT
+AAGATTTAGATACATAGACAATATAGGAGATGGGGAAATTGGGATATAAAAATATTTTGA
+TAGACTTTGATGATACAATTGTTGATTTTTATGATGCAGAAGAATGGGCGTTTCACTATA
+TGGCGAATGTTTTTAATCATAAAGCAACAAAGGATGATTTTTTAACATTTAAAAAAATCA
+ATCACCAACATTGGGAAGCTTTTCAACAAAATAAATTAACGAAGTCTGAAGTATTATCAG
+AACGATTTGTGAATTACTTCAAACATCATCAAATGGAAGTTGATGGGCATCGTGCAGATG
+TGTTATTTAGAAATGGATTAGCAGAAGCTAAAGTTAAATACTTTGATCAAACATTAGAAA
+CAATTGTCGAATTATCGAAAAGACATGATTTATATATTGTTACTAATGGTGTAACCGAAA
+CGCAAAAGAGAAGGTTAAATCAGACGCCGTTGCATAAATATATTAAAAAGATATTTATAT
+CTGAGGAAACAGGATATCAAAAACCTAATCCGGAATTTTTTAATTATGTTTTTAATGATA
+TTGGTGAGGATGAAAGACAGCACTCGATTATAGTTGGAGATTCTTTAACATCTGACATTC
+TAGGTGGAATCAATGCGGGTATAGCTACTTGCTGGTTTAATTTTAGAGGATTTGATCATA
+ATCCAGGAATTATACCTGATTATGAAATTAATTCATGGAAACAACTAAATGATATTGTAC
+GTTAAGACAAATAATTTGAAAATGATTTATATTAGCTTAAGAAAGTAATTGTAAAAACGA
+CACTACGAAAAGATGCATTTTCATGCTCGTAGTGTCGAATATTATTATCTTATGGTTTCC
+ACAATAAGACATCATGTCCCTCTATATTTTTAGCTTCCACATCTGTAAATCCATGATGTA
+AAAAGAAATCCTTAGAATCATTTCTGCCAATGGCTTTAATTGGCATATTGAAACTCTTTG
+CAAAATCAATCAATTCTGAAGCGTACCCTCTGTTTTGATATTTTGGTAATACTTCTAACT
+TCCATAATAATATATAATCTTCAAAATCTGGGAAGTAGATTTCTTCGACATCACCTTTTT
+TTAGTAATGCCATTCTAGCTCCTAATTGATCTCCGACAAATATGCCATAAAATGGTGAAT
+CTGAACTTGCATCAATCATTTGACCGTTTAACTCATTGACCATGTATAAGTCTTTGTTGC
+CAAACGCTCTAAAGTTTTCGAATAATTCGTCAGTTTTGTAATTAATTTCAAGACGTTTGA
+TTTCACTCATATTTATCTACCCCTTATTTGTTTACTACTATTATTATACATTAAACCACT
+TGTGTTTTTCATTGATTTGAAAATGTAAAACAATGAACATTATAAATTTTCCATGATTAA
+ATTGATTTTCAAGCCGTAAAATTGTCAATCACCGGTATAGACTTTATACTATAGTTTGTA
+ATCGCGTACTTAAGGAGAAAAAACATGGACTGTAAAGTAGTTAGTTTAAATGAAAAAGAT
+CAGTTTATACCAAAAATAAAGAGCAGTGACCCTGTAATAACAGGATTATTTCAATATGAT
+GCAGCTCAACAAACTAGTTTTGAAAAAAGGATGTCTAAAGAAAATAATGGAAGAGAAGCG
+GCATTAGCGAATGTTATTCGTGAATATATGAGTGATTTAAAGCTTTCAAATGAACAAGAA
+TTAAACATACAACATTTAGCTAATGGTTCAAAAGTTGTGATTGGTGGACAACAAGCAGGG
+CTTTTCGGGGGACCATTGTATACATTCCATAAAATATTTTCAATCATTACTTTATCTAAG
+GAATTAACGGATACACATAAGCAACAAGTAGTACCAGTTTTTTGGATTGCAGGAGAAGAT
+CATGATTTCGATGAAGTGAATCATACATTTGTTTATAACGAAAATCATGGGTCGCTGCAT
+AAGGTTAAATATCATACAATGGAGATGCCAGAGACGACAGTCTCTAGATATTATCCTGAT
+AAGGCTGAGTTGAAACAAACTTTAAAAACGATGTTCATTCATATGAAAGAAACTGTTCAT
+ACACAAGGTCTACTGGAGATTTGTGACAGAATTATTGACCAATATGACTCGTGGACTGAT
+ATGTTTAAAGCACTACTGCATGAAACATTTAAAGCATATGGCGTTCTATTTATAGATGCG
+CAGTTTGAGCCGTTAAGAAAAATGGAAGCGCCTATGTTTAAAAAGATTTTGAAAAAACAT
+CAGTTGCTTGATGATGCTTTTAGAGCAACACAACAACGTACTCAAAATCAAGGCTTGAAT
+GCGATGATACAAACAGATACAAATGTTCATTTATTCTTACATGATGAAAATATGCGCCAA
+TTAGTTTCGTATGATGGTAAGCATTTTAAATTAAATAAAACAGATAAGACATATATAAAG
\ No newline at end of file
diff --git a/t/data/query_5.gff b/t/data/query_5.gff
new file mode 100644
index 0000000..acb51e9
--- /dev/null
+++ b/t/data/query_5.gff
@@ -0,0 +1,271 @@
+##gff-version 3
+##sequence-region abc|SC|contig000001 1 15000
+abc|SC|contig000001 Prodigal:2.60 CDS 172 1131 . - 0 ID=3_1;gene=hly;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:Q2G1X0,protein motif:TIGRFAMs:TIGR01002,protein motif:Pfam:PF07968.6;locus_tag=abc_00001;product=Alpha-toxin,beta-channel forming cytolysin,Leukocidin/Hemolysin toxin family protein;protein_id=gnl|SC|abc_00001
+abc|SC|contig000001 Prodigal:2.60 CDS 1804 1950 . + 0 ID=abc_50002;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00002;product=hypothetical protein;protein_id=gnl|SC|abc_00002
+abc|SC|contig000001 Prodigal:2.60 CDS 1934 2131 . + 0 ID=abc_50003;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00003;product=hypothetical protein;protein_id=gnl|SC|abc_00003
+abc|SC|contig000001 Prodigal:2.60 CDS 2621 3337 . - 0 ID=abc_50004;inference=ab initio prediction:Prodigal:2.60,protein motif:CLUSTERS:PRK13350,protein motif:Pfam:PF02876.11;locus_tag=abc_00004;product=superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00004
+abc|SC|contig000001 Prodigal:2.60 CDS 3445 4170 . - 0 ID=3_2;gene=speH;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P0C0I6,protein motif:CLUSTERS:PRK13349,protein motif:Pfam:PF02876.11;locus_tag=abc_00005;note=SPE H;product=hypothetical protein,superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00005
+abc|SC|contig000001 Prodigal:2.60 CDS 4265 4990 . - 0 ID=abc_50006;inference=ab initio prediction:Prodigal:2.60,protein motif:CLUSTERS:PRK13043,protein motif:Pfam:PF02876.11;locus_tag=abc_00006;product=superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00006
+abc|SC|contig000001 Prodigal:2.60 CDS 5428 6429 . + 0 ID=3_3;eC_number=2.1.3.3;gene=argF;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P99073,protein motif:CLUSTERS:PRK04284,protein motif:Cdd:COG0078,protein motif:TIGRFAMs:TIGR00658,protein motif:Pfam:PF00185.1;locus_tag=abc_00007;product=Ornithine carbamoyltransferase,ornithine carbamoyltransferase,Ornithine carbamoyltransferase,ornithine carbamoyltransferase,Aspartate/ornithine carbamoyltransferase%2C As [...]
+abc|SC|contig000001 Prodigal:2.60 CDS 6449 7384 . + 0 ID=abc_50008;eC_number=2.7.2.2;gene=arcC1;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:Q7A627,protein motif:CLUSTERS:PRK12353,protein motif:TIGRFAMs:TIGR00746,protein motif:Pfam:PF00696.22;locus_tag=abc_00008;product=Carbamate kinase 1,putative amino acid kinase,carbamate kinase,Amino acid kinase family protein;protein_id=gnl|SC|abc_00008
+abc|SC|contig000001 RNAmmer:1.2 rRNA 7556 9112 . + 0 ID=abc_51705;inference=COORDINATES:profile:RNAmmer:1.2;locus_tag=abc_01705;product=16S ribosomal RNA
+abc|SC|contig000001 Prodigal:2.60 CDS 9419 9646 . + 0 ID=abc_50010;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00010;product=hypothetical protein;protein_id=gnl|SC|abc_00010
+abc|SC|contig000001 Prodigal:2.60 CDS 9952 10899 . - 0 ID=abc_50011;inference=ab initio prediction:Prodigal:2.60,protein motif:Pfam:PF03595.11;locus_tag=abc_00011;product=C4-dicarboxylate transporter/malic acid transport protein;protein_id=gnl|SC|abc_00011
+abc|SC|contig000001 Prodigal:2.60 CDS 11148 11336 . + 0 ID=abc_50012;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00012;product=hypothetical protein;protein_id=gnl|SC|abc_00012
+abc|SC|contig000001 Aragorn:1.2.34 tRNA 11803 11878 . - 0 ID=abc_50013;inference=COORDINATES:profile:Aragorn:1.2.34;locus_tag=abc_00013;product=tRNA-Arg(tct)
+abc|SC|contig000001 Prodigal:2.60 CDS 12241 12375 . + 0 ID=abc_50014;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P11699,protein motif:Pfam:PF05480.5;locus_tag=abc_00014;product=Gonococcal growth inhibitor III,Staphylococcus haemolytic protein;protein_id=gnl|SC|abc_00014
+abc|SC|contig000001 Prodigal:2.60 CDS 12432 12566 . + 0 ID=abc_50015;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P11699,protein motif:Pfam:PF05480.5;locus_tag=abc_00015;product=Gonococcal growth inhibitor III,Staphylococcus haemolytic protein;protein_id=gnl|SC|abc_00015
+abc|SC|contig000001 Prodigal:2.60 CDS 12699 13385 . + 0 ID=3_5;eC_number=3.-.-.-;gene=yfnB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:O06480,protein motif:CLUSTERS:PRK09449,protein motif:TIGRFAMs:TIGR02254,protein motif:Pfam:PF00702.1;locus_tag=abc_00016;product=Putative HAD-hydrolase yfnB,dUMP phosphatase,HAD hydrolase,haloacid dehalogenase-like hydrolase;protein_id=gnl|SC|abc_00016
+##FASTA
+>abc|SC|contig000001
+ACTGGCCGCCTAATTTTAAAAACTCCCCAAGCTGTAATTTAAGGGGGTTCTTTAAATTAT
+ATACCCACCACATTTTTTGGAGAACCCCAAACTAGCCGAAAAGGGGCATTTCTGAAGTTA
+ACGGCTAAAGTTATTTTTTATATTTCCCTGTCCATGAACAAAGGGGTTACATTAATTTGT
+AATTTCTTCTTTTTTTTAATCGATTCCCTATCTTTCTGAAGAGGGGTCTGTCCATTTATC
+ATTAGTATTGGTACTTTTCCAATTTCCCGAACTCCAATGCAAGGGGTAGTCATCACGAAC
+ACGTTCGTATATTATTTCTATATTTCCCTGTCGTTTGGATGCGGGGCTATCCATAGTAAT
+AACTGTAGCGAAGTTTTGTGAAAACCCCGAACATAATAGAGAGGGGGCTTTGTTAGGATC
+AAGGAAGTTCTCTGTTTCTTTCATACCCCCACTTCTAGTTTTGGGGAAAAGTTGATTGCC
+ATATACCGGGTTCCTTTAATCTCTACCCTATCGTCCCCAATTGGGGTTCACCATATTGTT
+AAATATCACTTTCCTTTCTACTTTTCCCTCACTTGGGCTCTCGGGGATTGTTTTGAAATC
+AGGTTGAACATATTTTTGTGTATGACCCATCCAAACATTTGCGGGGATAAGGCCGCCAAT
+ATTTCCTGTATCATTTTCAGTAACACCCCCGCTGAATCCATAGGGGAAAGTACTCATATA
+ATCTTTTGTATCAATTTAATTTCTTCCCTAGCAATCAGATATGGGGGCTACTTCATTATC
+AGGTAGTTGCAACTTTTCCTTAAAGCCCGAACGCCAGGCTAAGGGGCTTTTGTTAGCACC
+ATCTTCGCTATAAATTTTATATTGACCCGCACTGGTACCTTTGGGGCTAATAACTAGCAG
+ATTTTTATTGTGATTTTTATCATCGCCCAAACTATAAAATACGGGGTTGTGCATGCCATT
+ATCTTTATCATAAGTTTCTAAATCACCCGTTCTTACTGTAGTGGGGCTTCCAATATCTGT
+AGTACCGGTTTTAATTTTAATATCACCCTCTCCGGCATTAGCGGGGGGATTCATTAATAT
+AGAACCTAGCAATATTTTTGTTGTTCCCGAGCTGACTATACGGGGGTTCATTTTCATCAT
+ACTTCTATTTTTTTTTTCGATTTGACCCAACCATAATCAATAGGGGAATTTAGAATATTG
+AAGTTGAGACATATTTTATATTTATCCCCGTCTATATTAGTAGGGGTAATGTAGCAACTG
+ATAAATTACTGAGTTTTGATGAGTGCCCATTCTAAGAATATGGGGGTAACTTTTATTTAA
+AATTTGAAAGGAAGTTTTTCAATTTCCCGGGCTAGTCAAAGTGGGGTAAATTCTTTATGA
+AACAAGGAAAAGACTTTGCTAATTTCCCTGACTAATTTCTTTGGGGCTAATGATTTGTTT
+AATTTAAAAATGTATTTGATTACAACCCAAACATACAAATATGGGGGAATTAAATCAATT
+AATTAACTATTAAATTTAAATTAAACCCATACTAACTACTGTGGGGTAATAAATAGAAAT
+AGAGAAAAAGGGTATTTATTATGTTCCCAATCTCGTCGGGAAGGGGTTTTGCCATTACAT
+AGAAATATCTAATATTTAATGAAAACCCATCCTATGTATTTTGGGGATAGTGTAAAATAT
+AATATGTAAAATAATTTGTAGATTTCCCGTTCGAGGCATTATGGGGAAATTTTGAGTATA
+AGTTAGCTTTTAATTTTGAATCTTACCCAAACTTGATTAATAGGGGTATGATAGGGGATT
+AAAATGAAACTATTTTTTATCGTATCCCTTACTATTATATGGGGGGATATATTTTTAGGA
+AATGAAATTATCCATTTACTGACTGCCCTAACAACAACATTGGGGGTTGTTAATTCAAGA
+AAGGGGATTAAAAATTTCAGAGTTGCCCAATCTTATAAACTCGGGGCAATCTTTGTTTGA
+ATCTGAATCAGGCTTTTAAATTTCGCCCAATCCAGGAGTTCCGGGGCAAACAGTACAAGA
+ATTAAGAAATGGGATTTCCAAACTACCCGATCCTAGATTTAGGGGGATTATTAAACTTTA
+AAGTTACTATGTCTTTTTAAAAGAACCCTAACCATGGGACAAGGGGGTATTGCTATAATA
+ATTGAATCATTAAATTTAGGAATAGCCCCTACGACATAATAAGGGGATGTCTTAGGCTCT
+ACAATATTATATTGTTTGTAGTTGACCCAATCAAAATGACCAGGGGACAAGCATTTTTGG
+AGCCCCAACACAGATTTTGACGAAACCCCAGCTTACAATAATGGGGAAGTTGGGGATGGG
+ACCCAACACAGAGATTTTCAAAAAGCCCTTCCACAGACAATGGGGGTTGGCGGGGCCCCA
+ACATAGAGAAATTCTTTAAGAAATTCCCCAGCCAATGCAAGTGGGGGAGTGACAACGAAA
+AAAATTTTATAAAATTTCATTTCTGCCCCATCCCTACTCCCAGGGGCATTTAAATATATA
+AAAAATTTCACCTATTTTATACATCCCCCACCTTAAAAATTAGGGGTTAAATAATCTGAT
+ATGGAATTAAAGTGTTTGAAGTATACCCCACCTTCATATACTGGGGAAAGAGGACGTCAA
+AAGTTATTTTATTATTTTTTTTAACCCCAACCTTTGCTAGATGGGGATGTAATCTTTTGC
+ATAAATCAATAGTGTTTTTATTACCCCCACCCGTGATCTTAAGGGGACCTTTATTACGAT
+ATTCGGTATATAATTTTTTATTTTTCCCTAACGCTTCTCGTGGGGGGAAATCGATTTCTT
+ACAATGTTAATACTTTTTTATTGCCCCCGTACATTTTATGCGGGGGAATAATCGTTTGTA
+ATTTATCTTTGTATTTTACAAAAAGCCCATACGTTTTATCAGGGGGTTTTGCGGCTGGTG
+AAACGCCACCTGTATTTGTCTCTCTCCCAGACCACCATAACTGGGGAGTATCTTTGTCTT
+ATAGTCCAAACACATTTACGTAACGCCCTTTCAACTGATTAAGGGGTCCCCAACTTTCAG
+AGCCCCATAAAGATTTTTGTGCTGACCCTGACTATCTCTTAAGGGGAACATAAATGTTTC
+AATTATCATATTGATTTAGCCATTTCCCTGACAATGAAAAATGGGGCTGTGTGTAATATT
+AAATTAATTCATTGTTTTTAGTTTCCCCTTGCCCAATGCTATGGGGTTTAGCTTCAGAGT
+AAAAACTAAATACTTTTTTTTGATTCCCAGGCAATACAGTACGGGGTAGTAATAATGTTG
+ACGTTAAAATTATATTTTTCGTGATCCCCTTCCTCATTAGAAGGGGTCCTTTCAGAGGAA
+ACATGATACGAGGATTTAGAAATTTCCCTGTCAGCGAAGTCAGGGGAGTATTTGCGATTA
+ATTTTATTAACTCCTTTATTATTGTCCCTTTCATTTTTCGAGGGGGACTTCAATTTTTGC
+ATTTTGAGGTTTTTTTTCATATCTACCCGCACCAGTTGATGGGGGGCTTTTACTTAAATC
+AATTGTGTAGTTATTTTCTGTACCTCCCATTCTAATTTGTCCGGGGTTATAAGAATTATT
+ATATAATTTTTTACTTTTAATTAATCCCTGACGAATACGAAAGGGGAATTCTTTTAAAGT
+AAAAACAGGCTTATTTTCTTCATAACCCGGACATCCGCCAGTGGGGGTTTCTGCTTTATC
+ATTATATGTTACATTTTGTTTATAGCCCTTACCGTTAGATGTGGGGGCAGGAGTAACACC
+ACCAGTAAACGTTTTTTGAGATAATCCCAAACAATCAATGGTGGGGTGGTCTTTTATGCC
+AAAAATATCAACGCTTTTATTTCTTCCCTGGCTGATATTGCCGGGGCTTTCAGGTCCATA
+AACTTGAATATGACTTTACCAAGAACCCTGTCACAACGTTGCGGGGATCGTACCGTTATC
+ATTTTGCCATAACGTTTTGTTAGAGCCCGTTCAATATTTTTGGGGGTAATATTTAGTTAA
+ATCATTAACGTTAGTTTCGTTTTGACCCATACAATAAGCTTTGGGGTCAGATGAAGAATT
+AATAGGTGTATTAGTTTATTGTGTACCCGCTCTACCTAATAGGGGGAATGTTGTTGATAA
+AATAATTTTTTTCGTTTTGTTATTGCCCATTCGAATTTCTCCGGGGAGTATTGTTGGAAT
+ATTTAATTATAAAATTTGGTTAATTCCCTAACTGAAATTATCGGGGTTTACAAAAGGTAA
+AAGGTTAGTTAGATTTTTCGAGTATCCCTTCCATTTGTGCATGGGGAGGATTTTTAACAT
+AACGGTTTGTGTCATTTAATTTTAACCCTTTCCTTAAATCAAGGGGGTAATTATTTCCAT
+AAGCAGTTATCTTATTTTGACCTTTCCCAAACTCTCCGTTATGGGGCTTTTTATTCTTTA
+ATAATGTTTGACGATTTCGGAAATCCCCTTCCTTTAAAGTTAGGGGTGGTTTATTTCCTT
+AGTAAAATTCATGTTTTCCGATGATCCCTTGCTGTTTATCACGGGGTTTTAAAAATAGTC
+AATAAGGTTTATCATTTGAAGTAGCCCCTGGCGTAACACCACGGGGAAATGTTTCATCAT
+AAGTCCAGTAACCTTTTACTGTGTCCCCATCCTTAGTTCCAAGGGGATCAACGTATTTAT
+ATCTTAACTGATTATTTTTTCCCCACCCCTCCGATCCAAACAGGGGAATATGACTATACC
+AAACCCACGTTTGCTTTGTTGCATGCCCGCTCCCATTGGGCTGGGGCCATAGCCATTTTC
+AAGATAATGAAAAATTTGGCTGAGTCCCATACTTGATTAACTGGGGGATATTAGTCTCGT
+ATTCACTGATATTATTTGCTTTTGCCCCAGACGAAAAACTGAGGGGTGTTTTAGGAAGTT
+ATGTTGATGTGGTTTTTAAAAGTAACCCTGCCGTTGATAAAAGGGGTTTATTCATGATGT
+ACTTTTTCATATGATTTTCTCCTTTCCCTGACTTACCCAAAGGGGGTAAGCTATTACACC
+AATTCGGAATTAAATTTAAGCTAAACCCATGCTAAATAAACTGGGGCAGTTAGTAGTGTT
+ATTTAAGCAAAACTTTTCATTTTTACCCTTTCGACAGAAACAGGGGTTAATAAAGTAGGC
+AGGAGTTATATATTTTTAACGACACCCCACACTTATTCTCTAGGGGATTGCATTAAATTG
+ATTGATAATTGAATTTTCTAACTACCCCAAACATAGTTATACGGGGAATGTAGTACTTAT
+ATTAATTATTTCCTTTTACTTAAATCCCATACTAATAAAATGGGGGTTTAATTATTGATA
+AAATATTACAAATTTTTATAGTAGGCCCTGTCTATTTTGTATGGGGTTACAATTTAGGTG
+AAACTAAAATAAAATTTGTTGTTATCCCTGACAAATTTACGAGGGGGAAGTTTTTTAACT
+ATATTAGACTTTTCTTTACAAGAGGCCCAATCCTTATTAACAGGGGCCGAGGATTTAAAA
+AGTGCTAAATATATTTTCACTGAAACCCCTACGTTAAAAAATGGGGATATTGCACTGTTA
+ATTGAAAAAGATTCTTTAAGAACGCCCCGTGCATTTGAAGTTGGGGCGCATGATCAAGGT
+ACAAATGTAACTTATTTAGGCCCAACCCGATCACAAATGGGTGGGGAAGAAACAACTAAA
+AATACTGCACGTGTTTTTGGTGGAACCCATGCTGGCATTGAAGGGGGTGGTTTTTCACAA
+AGAACAGTAGAAACTTTAGCTGAAACCCCAGCCGTACCAGTGGGGGATGGTTTAACTGAT
+AAAGATCATCCTACTTTAGTTCTTGCCCATTCCTTAACAGCAGGGGAAGTCTTAAAAAAA
+AATTATGCAGATATTTTCTTTACATCCCTTGCAGATGGTCGTGGGGACGTTGCAAATGCA
+ATAATGCAAGGTGCTTTCATTATGGCCCTGACCTTCCATTTAGGGGGTCCAAAAGAATTA
+AATCCAACAGATGATTTATTAAATCCCCGTACAAATATTGCCGGGGAAAATGGTGGCAAC
+ATATTAATCACAGATTTTATTGACCCCCGTGCAAAAGGTTCGGGGGTAATTTACACTGAT
+ATTTGGGTATCAATTTTTGAACCTGCCCAAGCATGGAAAGAAGGGGTTGAATTATTGAAA
+ACATATCAAGTAAATTTAGAAATGACCCATACAACTGGTAATGGGGATGTTATTTTTGAG
+AATTGCTTACCATCTTTCCATAATGCCCATACGAAAATTGGTGGGGAAATTTTTGAAAAA
+AATGGTATTCGAGATTTGGAAGTTACCCATGCAGTATTCGAAGGGGAAGCTTCAGTTGTA
+ATCCAAGAAGCTGATTTCAGAATGCCCCCAACCAAAGCAGTCGGGGTTGCTACATTGGGT
+AAATTTTAAATGATTTTAGGAAGTGCCCATGCTGGCGAAAATGGGGGTAGCATTAGGTGG
+AAATGCTTTAGGAATTTCACCTCAACCCCAACTCGAGCTTGTGGGGAATACTGCGAAATC
+ATTAGTAGGATTAATTTCAAAAGGACCCGAGCTTGTTATTAGGGGGGGTAATGGACCACA
+AGTTGGAAGCATTATTTTGGGACTTCCCTATCCTGCAGAACAGGGGCAAGGTCCGGCATT
+ACCATTTGCTGAATTTTGCGCAATGCCCCAACCTTACATCGGGGGGCAATTACAAGAAAG
+ATTACAAAATGAATTTTATTCTATTCCCATGCATAAACAAGTGGGGACACTAGTGACACA
+AGTTGAAGTTGATGTTTATGATCCGCCCTTTCACAATCCTTCGGGGCCAATTGGGTTATT
+ATACAACAAAGAAGTTTCTGAACAACCCCAACAAGAAAAAGGGGGGATATTTGTTGAAGA
+AGCTGGAAGAGGATTTTGACGCGTTCCCCCTCCACCACAACCGGGGTCTATTATTGAATT
+AGAGAGTATTAAAATTTTTATTAAACCCGATCCACTCGTTATGGGGGCTGGTGGTGGAGG
+AATACCAGTAATTATTTAGCAACATCCCGGTCTTAAAGGTATGGGGGCAGTTATAGACAA
+AGATAAAACAAGTGTTTTGTTGGGTCCCAATCTTCAATGCGAGGGGTTGATTATTTTAAC
+AGCAATTGATTATGTTTATATTAATCCCAACCCTGAAAACCAGGGGCCTTTGAAAACAAC
+AAATGTTGATGAATTTTAACGATATCCCGACCAAAATCAATTGGGGAAAGGAAGTATGTT
+ACCAAAAATTGAAGTTTCCATATCACCCATTCAAAACAATCCGGGGGGAAGTGTGCTTAT
+AACATCATTAAATGTTTTAGATGCTCCCTTACAGGGTAAAGTGGGGACTGTGATTAAAAA
+ATAATTGAATTGAATTTCTTTTCAACCCCTACATGTCAAATGGGGGATTTTTATTATTTA
+AGTGCACCCCCTGATTTTAATGCCTCCCTTTCGATGCGGGGTGGGGTTTCTTAATTTATA
+ATTATAAAATCTTTTTTGTAGAAATCCCAGGCTAAATGTCGAGGGGGATGAAACCGTGGA
+AAATACAATTAATGTTTGTGAAAAGCCCAAACGATTTAAATTGGGGATGCCAGGTGCATT
+AATGATTTTATTCATTTTAACGGTTCCCGCACTTATAGCAACGGGGGTTATTCCTGCTGG
+AGCATATTCTAAACTTTCTTACGAACCCTCACCCCAAGAACTGGGGATAGTTAACCCTCA
+AAACCAAGTGAAAATTTTTCCGGGTCCCCAACAGGAACTAGAGGGGATGGGGGTTAAAAT
+AAAGATTGAACAATTTTAATCAGGTCCCATTCATAAGCCAGTGGGGATTCCGAATACTTA
+AGAAAGATTAAAGCTTTATCCAGCTCCCCCACAACAAATAACGGGGAGCATGGTTGAAGG
+AACGATAGAAGCGGTTTATATCATGCCCTTCCTTCTTGTACTGGGGGGACTTATTGGCGT
+AGTTCAAGCCAGTGTTTCTTTTGAACCCGGACTGTTAGCTTTGGGGAAGAAAACAAAAGG
+ACATGAATTTATGCTTTTTGTGTTTCCCTCACTACTAATGATGGGGGGCGGGACGTTATG
+AGGTATTGAAGAAGTTTCTGTAGCACCCTATCCGATTTTAGTGGGGATATTTATAGCGTT
+AGGATACGATTCTATTTTTTCAGTTCCCGCCCTATTCCTTGCGGGGTCTGTCGGTAGTAC
+ATTTTCAACTATTATTTCGTTCTCGCCCGTACTTGCCTCTAAGGGGGCTGGTACAACTTT
+AACGGATGGCTTGTTTTGGAGAATACCCGCTCGTATTGTCGGGGGGATTTTTGTTATTAG
+ATATTTATATTGGTTTTGTAAAAAACCCAAACACGATCCTAAGGGGTCATATTCTTATGA
+AGACAAAGATGCTTTTTAACAGCAACCCTCTCTATTAAAAGAGGGGGATAGTGCCCATTT
+AACTTTGCGTAAGATTTTAATCCTTCCCTTACTTGTACTACCGGGGCCAATTATGGTATG
+AGGAGTTATGACGCTTTGTTGGTGGCCCCCACTTATGGCTTCGGGGTTTTTAATATTTAC
+AATTATAATAATGTTTTTTGCTGGGCCCGGTCAATCTGGATTGGGGGAAAAAGGAACTGT
+AGATGCATTTGTCATTTGTGCATCACCCTTACTAGGTGTATCGGGGATTATTGGTTTAGC
+ACGAGGTATTAATTTTTTGTTGAATCCCGGTCTGATTTCAGAGGGGATCTTACACTTTTC
+ATCATCTTTAGTTCTTTATATGAGTCCCCCACTATTTATCATGGGGTTACTATTTATTTT
+ATTCTGTTTAGGTTTTTTCGTGCCACCCTCTCCTGGATTAGCGGGGTTATCAATGCCTAT
+ATTTGCACCACTAGTTTATACAGTACCCATACCAAGATTCGTGGGGGTTACGACATATCA
+ATTTGGTCAATATGTTTTGTTATTCCCCGCGCCGACTGGACTGGGGATGGCCACACTACA
+AATGTTAAACATGCTTTATTCACATCCCTTCCGATTTGTATGGGGGGTAGTTGCTTTTGT
+ATTGATTTTCGGTGTTTGAGTACTACCCACGCAAGTACTAATGGGGTCATAATTTGAAAT
+ACTATATTATAAAATTTCTAATTGGCCCTTACGCATCTCGTAGGGGTGTAGAAATACTAA
+ACTAAGCGAGGTGCTTTATTATTTTCCCTTACGAAAATAATGGGGGTAATGATAACACTA
+ATAAGTAATTGATATTTTGCTCTATCCCATACTGATATTTTTGGGGTTTGTTTTTAATGT
+AATGTTAGATCTATTTTATATTATACCCATCCTGGTAAATATGGGGTTGCTGTAAACAGT
+ATTTGTAACACATGTTTCATATGGTCCCGAACATAGCATATAGGGGGGATGGCTATAAAT
+AACACATTTGACAATTTTTTTAGATCCCCTACCTGGAATATGGGGGGTATTATTATTTAG
+AAAATATTTTGTGGTTTATGCAAATCCCGTGCTTGATTGGAAGGGGAGATGGTATTTGCT
+AGAAAACATACCACTTTTGCCAATTCCCTTACTTATTCTGATGGGGATTTTCGGAGTACC
+ATCTGAAATGATAATTTATAGGCAACCCAAACATAACGGTGTGGGGTTTATCGATATTTA
+AAGGTGATAAAATTTTTCAACTATTCCCAAGCCTAAAATAAAGGGGTTTATTAATTATTT
+AATTGGTATATTAGTTTTGGCGTTTCCCGCTCATATATTATTGGGGTAAAGGTTAGAGTG
+AAACGTGTTTATGATTTAGACGTTCCCCTATCGTTACTACAGGGGGAGTCAGAAGGTATC
+ATTGATAAGATCATTTTAAATCAAACCCGCACTGATATACACGGGGAAGAGGCAAGATTA
+ACTGCCTCTTTTTTTTTTATTAAATCCCCGTCTTAATTCTTGGGGGTAGTGTTACTGAGA
+AGCATTACGAAGAATTTTATCTTGACCCTCCCTTTTTAAAAAGGGGTGAAGATATCCTAT
+AAAGACTCTAAGTATTTTTACAGTGCCCAATCACACTTCGATGGGGAAAAGACCTTTCCA
+AATATCTGGAAACATTTGTACAGGCCCCCTGCTCTTTAAAGCGGGGGCTGAGATTACTAA
+AGGGAATGTGAAAGTTTAAAATACGCCCGAACAAGGTTCTTTGGGGAATTTAGGCAATTG
+AATAATGATATAAATTTAAAATATTCCCGCTCATATTAAAAAGGGGATTACGATAAAAGC
+ATTCGCCTTAGGAATTTCTATAACACCCGCTCCAGCGACTAAGGGGAATGGTGCACAAAT
+AGTCGATGTGTTCGTTTTGATTGACCCCTGCCATGGAAATGCGGGGAATCGCTTGAAAAC
+AATAGGTAAGACAATTTAAGTAGCTCCCAAGCCATATATTACGGGGAATTGACCTATGAA
+AAAACATCCGCTAATTTGTGCCGTCCCCCCTCCGATAGCAATGGGGATAAAAAGTACAGT
+ACACGAAGGATAAATTTTTTCAAGTCCCAAACCTTTTAAATAGGGGATTGAAAAAATAAT
+AATATGCGTCATAATTTCCACAAGGCCCAAACTCCAAATAGGGGGGATTAAGCTATTGAT
+AAAAGTTATGTTACTTTAAAATGTACCCAAACAAGTAGTACCGGGGAAGCCAGACATGAA
+AAATGTTGTGAACATTTATGAAACTCCCGGACTGTTTAATTGGGGGTTCACATTATTAAA
+ATATTTGATCATAGTTTATAAAAGGCCCATCCAAATCAAGAAGGGGAAGATTCCGCAAAC
+AGCGTTTAAAGTAATTTATAAGTCTCCCAATCGATTACCCAGGGGGAATAATCCTAAGAC
+AAGTCCTGACGTTATTTGAGGTGCTCCCTGACGTCTCATGATGGGGAACCTTTCTTATGT
+AATTTTCTTCACTATTTATATCATGCCCGCTCTGGCCAATTAGGGGGAAGAGTGTGTACT
+ATTACGTTATTAGATTTTGTATATTCCCTTGCTAGACACATAGGGGACATTTAAATCTCA
+AAATTAATGATATTTTTGGTATGCTCCCCAACCTAAATATTGGGGGATGTGGAAAAGTAA
+ATATTTAATTTAAATTTTGATTGAACCCTTACAAGGGGGTGTGGGGAATGAGAAATCAAA
+ATCAAAAACTATTATTTAGTGATTTCCCCAGCTTACATATATGGGGACAAACAGGAGTTC
+AACAAAGCACAATATTTAGAATGAGCCCAAACGAAAGATCATGGGGCAATATGTCATTGA
+AAAACGCTGAACTATTTTATAAATTCCCCAACAGTATATTTAGGGGTGAAAATTAAGAAG
+AATAATTAGTGAGTTTTATAATTAACCCACCCCGTCTCGATGGGGGTGGTTATTTTTTTA
+AATGTATTTAATTATTTGATTTCGGCCCCCTCAAAAGTCCCTGGGGTTTTGAATAGTATC
+AAAATCTATAGGAATTTTATAATAACCCAAACCTCTACGCATGGGGATGGTGAGTGTTAA
+AAATCTTGGTGTAGTTTTGGTGTAGCCCAGGCGCAGTATAGAGGGGATTTGAGCACAAAA
+ATACTTAATTAAAATTTTATAAACACCCGTCCGACGCGTGTCGGGGGTGTGTCAAAAAAT
+ACTATGACGAATAATTTTGCTTGTTCCCATTCCTGTATTTTCGGGGCTTATGCGGGGGAC
+ATTTTGGTGACGCATTTTACTATATCCCTGACATTCAAAACAGGGGGAGCCCCGTAATCA
+AGGAACTCTTTTGTTTTGTAATGCGCCCAAACATACCTATAAGGGGCCTGGGAGGGATTC
+AAACCCCCGACCGATTTCTTAGAAGCCCATTCCTCTATCCAGGGGGGCTACCAGGACACG
+ATTAACAACACAAGTTTTATTATATCCCAATCAACTTAAATTGGGGATACCTTGTAAATA
+AAAAATGTTTATATTTTTCACTATTCCCGAGCTATTTATCTAGGGGGGTTCAATAAGACT
+AAAATGCGAATTCATTTAACTTAATCCCGTTCAATACAGTTTGGGGTGCCTAACTGTATT
+ACTTTTCTCTTTAATTTACAGTTAACCCCATCATAAGATGTTGGGGGGATAAACAAACTA
+ATTGCATCAAATTTTTTTTAAAATACCCACACCAAAACGTTAGGGGAATAACATTTCGGT
+AATTTAAAAGCTACTTTCGTTTTTGCCCTCTCCAAATTTAAAGGGGAAGGAGTGTTTTCA
+ATGGAAGGTTTATTTTTCGCAATTACCCATACCGTAACTGCAGGGGTTAATAATGATGGC
+ACAAAATTAGGCACTTTCATTGTGACCCTCGCTGAAAATGGCGGGGGTTTATTAGGTAAA
+ATATTCGGATTCTATTTTCAATATGCCCTGTCAGTAATCAGTGGGGTTTCAAAGGTGAGG
+AAGAGATTTAAATGTTTGGACTAGCCCCAGCCATCGCAAATAGGGGGCAAGCTGCACAAC
+AACATGATAGTGTGTTTTTAGGCACCCCTATCGTAGACATCGGGGGTAACGGTGTGGGTT
+AACTAGGTAAATTATTTGGATTCTACCCTAACAACTAATATTGGGGAAAATAAACTGGGT
+AAGCATACTTTAATTTTATGCACTCCCCTTACTTTATTTGCAGGGGTTTGAGCCTCTGTT
+AAGATTTAGATACATTTACAATATACCCGATCGGGAAATTGGGGGGTAAAAATATTTTGA
+AAGACTTTGATGATTTTATTGTTGACCCTTACGATGCAGAAGGGGGGGCGTTTCACTATA
+AGGCGAATGTTTTTTTTCATAAAGCCCCAAACGATGATTTTTGGGGATTTAAAAAAATCA
+ATCACCAACATTGGTTTGCTTTTCACCCAAACAAATTAACGAGGGGTGAAGTATTATCAG
+AACGATTTGTGAATTTTTTCAAACACCCTCACATGGAAGTTGGGGGGCATCGTGCAGATG
+AGTTATTTAGAAATTTTTTAGCAGACCCTAACGTTAAATACTGGGGTCAAACATTAGAAA
+AAATTGTCGAATTATTTAAAAGACACCCTTTCTATATTGTTAGGGGTGGTGTAACCGAAA
+AGCAAAAGAGAAGGTTTAATCAGACCCCGTTCCATAAATATAGGGGAAAGATATTTATAT
+ATGAGGAAACAGGATTTCAAAAACCCCCTCCCGAATTTTTTAGGGGTGTTTTTAATGATA
+ATGGTGAGGATGAATTTCAGCACTCCCCTATCGTTGGAGATTGGGGAACATCTGACATTC
+AAGGTGGAATCAATTTTGGTATAGCCCCTTGCTGGTTTAATTGGGGAGGATTTGATCATA
+ATCCAGGAATTATATTTGATTATGACCCTAACTCATGGAAACGGGGAAATGATATTGTAC
+ATTAAGACAAATAATTTGAAAATGACCCATACTAGCTTAAGAGGGGAATTGTAAAAACGA
+AACTACGAAAAGATTTTTTTTCATGCCCGTACTGTCGAATATGGGGATCTTATGGTTTCC
+ACAATAAGACATCATTTCCCTCTATCCCTTTCGCTTCCACATGGGGAAATCCATGATGTA
+AAAAGAAATCCTTATTTTCATTTCTCCCAATCGCTTTAATTGGGGGATTGAAACTCTTTG
+AAAAATCAATCAATTTTGAAGCGTACCCTCTCTTTTGATATTGGGGTAATACTTCTAACT
+ACCATAATAATATATTTTCTTCAAACCCTGGCAAGTAGATTTGGGGGACATCACCTTTTT
+ATAGTAATGCCATTTTTGCTCCTAACCCATCCCCGACAAATAGGGGATAAAATGGTGAAT
+ATGAACTTGCATCATTTATTTGACCCCCTAACTCATTGACCAGGGGTAAGTCTTTGTTGC
+AAAACGCTCTAAAGTTTTCGAATAACCCGTCCGTTTTGTAATGGGGTTCAAGACGTTTGA
+ATTCACTCATATTTTTTTACCCCTTCCCTGTCTACTACTATTGGGGTACATTAAACCACT
+AGTGTTTTTCATTGTTTTGAAAATGCCCAACCATGAACATTAGGGGTTTTCCATGATTAA
+ATTGATTTTCAAGCTTTAAAATTGTCCCTCACCGGTATAGACGGGGTACTATAGTTTGTA
+ATCGCGTACTTAAGTTTAAAAAACACCCACTCTAAAGTAGTTGGGGTAAATGAAAAAGAT
+AAGTTTATACCAAATTTAAAGAGCACCCACCCTGTAATAACAGGGGTATTTCAATATGAT
+ACAGCTCAACAAACTTTTTTTGAAACCCGGACGTCTAAAGAAGGGGATGGAAGAGAAGCG
+ACATTAGCGAATGTTTTTCGTGAATCCCTGACTGATTTAAAGGGGGCAAATGAACAAGAA
+ATAAACATACAACATTTAGCTAATGCCCCAACAGTTGTGATTGGGGGACAACAAGCAGGG
+ATTTTCGGGGGACCTTTGTATACATCCCATACAATATTTTCAGGGGTTACTTTATCTAAG
+AAATTAACGGATACTTTTAAGCAACCCCTAGCACCAGTTTTTGGGGTTGCAGGAGAAGAT
+AATGATTTCGATGATTTGAATCATACCCTTGCTTATAACGAAGGGGATGGGTCGCTGCAT
+AAGGTTAAATATCATTTAATGGAGACCCCAGCGACGACAGTCGGGGGATATTATCCTGAT
+AAGGCTGAGTTGAATTTAACTTTAACCCCGACGTTCATTCATGGGGAAGAAACTGTTCAT
+ACACAAGGTCTACTTTTGATTTGTGCCCGAACTATTGACCAAGGGGACTCGTGGACTGAT
+ATGTTTAAAGCACTTTTGCATGAAACCCTTACAGCATATGGCGGGGTATTTATAGATGCG
+AAGTTTGAGCCGTTTTTAAAAATGGCCCCGCCTATGTTTAAAGGGGTTTTGAAAAAACAT
+AAGTTGCTTGATGATTTTTTTAGAGCCCCACCACAACGTACTGGGGATCAAGGCTTGAAT
+ACGATGATACAAACTTTTACAAATGCCCATTCATTCTTACATGGGGAAAATATGCGCCAA
+ATAGTTTCGTATGATTTTAAGCATTCCCAATCAAATAAAACAGGGGAGACATATATAAAG
\ No newline at end of file
diff --git a/t/data/query_6.gff b/t/data/query_6.gff
new file mode 100644
index 0000000..135faac
--- /dev/null
+++ b/t/data/query_6.gff
@@ -0,0 +1,271 @@
+##gff-version 3
+##sequence-region abc|SC|contig000001 1 15000
+abc|SC|contig000001 Prodigal:2.60 CDS 172 1131 . - 0 ID=3_1;gene=hly;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:Q2G1X0,protein motif:TIGRFAMs:TIGR01002,protein motif:Pfam:PF07968.6;locus_tag=abc_00001;product=Alpha-toxin,beta-channel forming cytolysin,Leukocidin/Hemolysin toxin family protein;protein_id=gnl|SC|abc_00001
+abc|SC|contig000001 Prodigal:2.60 CDS 1804 1950 . + 0 ID=abc_00002;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00002;product=hypothetical protein;protein_id=gnl|SC|abc_00002
+abc|SC|contig000001 Prodigal:2.60 CDS 1934 2131 . + 0 ID=abc_00003;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00003;product=hypothetical protein;protein_id=gnl|SC|abc_00003
+abc|SC|contig000001 Prodigal:2.60 CDS 2621 3337 . - 0 ID=abc_00004;inference=ab initio prediction:Prodigal:2.60,protein motif:CLUSTERS:PRK13350,protein motif:Pfam:PF02876.11;locus_tag=abc_00004;product=superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00004
+abc|SC|contig000001 Prodigal:2.60 CDS 3445 4170 . - 0 ID=3_2;gene=speH;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P0C0I6,protein motif:CLUSTERS:PRK13349,protein motif:Pfam:PF02876.11;locus_tag=abc_00005;note=SPE H;product=hypothetical protein,superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00005
+abc|SC|contig000001 Prodigal:2.60 CDS 4265 4990 . - 0 ID=abc_00006;inference=ab initio prediction:Prodigal:2.60,protein motif:CLUSTERS:PRK13043,protein motif:Pfam:PF02876.11;locus_tag=abc_00006;product=superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00006
+abc|SC|contig000001 Prodigal:2.60 CDS 5428 6429 . + 0 ID=3_3;eC_number=2.1.3.3;gene=argF;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P99073,protein motif:CLUSTERS:PRK04284,protein motif:Cdd:COG0078,protein motif:TIGRFAMs:TIGR00658,protein motif:Pfam:PF00185.1;locus_tag=abc_00007;product=Ornithine carbamoyltransferase,ornithine carbamoyltransferase,Ornithine carbamoyltransferase,ornithine carbamoyltransferase,Aspartate/ornithine carbamoyltransferase%2C As [...]
+abc|SC|contig000001 Prodigal:2.60 CDS 6449 7384 . + 0 ID=abc_00008;eC_number=2.7.2.2;gene=arcC1;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:Q7A627,protein motif:CLUSTERS:PRK12353,protein motif:TIGRFAMs:TIGR00746,protein motif:Pfam:PF00696.22;locus_tag=abc_00008;product=Carbamate kinase 1,putative amino acid kinase,carbamate kinase,Amino acid kinase family protein;protein_id=gnl|SC|abc_00008
+abc|SC|contig000001 RNAmmer:1.2 rRNA 7556 9112 . + 0 ID=abc_01705;inference=COORDINATES:profile:RNAmmer:1.2;locus_tag=abc_01705;product=16S ribosomal RNA
+abc|SC|contig000001 Prodigal:2.60 CDS 9419 9646 . + 0 ID=abc_00010;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00010;product=hypothetical protein;protein_id=gnl|SC|abc_00010
+abc|SC|contig000001 Prodigal:2.60 CDS 9952 10899 . - 0 ID=abc_00011;inference=ab initio prediction:Prodigal:2.60,protein motif:Pfam:PF03595.11;locus_tag=abc_00011;product=C4-dicarboxylate transporter/malic acid transport protein;protein_id=gnl|SC|abc_00011
+abc|SC|contig000001 Prodigal:2.60 CDS 11148 11336 . + 0 ID=abc_00012;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00012;product=hypothetical protein;protein_id=gnl|SC|abc_00012
+abc|SC|contig000001 Aragorn:1.2.34 tRNA 11803 11878 . - 0 ID=abc_00013;inference=COORDINATES:profile:Aragorn:1.2.34;locus_tag=abc_00013;product=tRNA-Arg(tct)
+abc|SC|contig000001 Prodigal:2.60 CDS 12241 12375 . + 0 ID=abc_00014;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P11699,protein motif:Pfam:PF05480.5;locus_tag=abc_00014;product=Gonococcal growth inhibitor III,Staphylococcus haemolytic protein;protein_id=gnl|SC|abc_00014
+abc|SC|contig000001 Prodigal:2.60 CDS 12432 12566 . + 0 ID=abc_00015;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P11699,protein motif:Pfam:PF05480.5;locus_tag=abc_00015;product=Gonococcal growth inhibitor III,Staphylococcus haemolytic protein;protein_id=gnl|SC|abc_00015
+abc|SC|contig000001 Prodigal:2.60 CDS 12699 13385 . + 0 ID=3_5;eC_number=3.-.-.-;gene=yfnB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:O06480,protein motif:CLUSTERS:PRK09449,protein motif:TIGRFAMs:TIGR02254,protein motif:Pfam:PF00702.1;locus_tag=abc_00016;product=Putative HAD-hydrolase yfnB,dUMP phosphatase,HAD hydrolase,haloacid dehalogenase-like hydrolase;protein_id=gnl|SC|abc_00016
+##FASTA
+>abc|SC|contig000001
+ACTGGCCGCCTAATTTTAAAAACTCCCCAAGCTGTAATTTAAGGGGGTTCTTTAAATTAT
+ATACCCACCACATTTTTTGGAGAACCCCAAACTAGCCGAAAAGGGGCATTTCTGAAGTTA
+ACGGCTAAAGTTATTTTTTATATTTCCCTGTCCATGAACAAAGGGGTTACATTAATTTGT
+AATTTCTTCTTTTTTTTAATCGATTCCCTATCTTTCTGAAGAGGGGTCTGTCCATTTATC
+ATTAGTATTGGTACTTTTCCAATTTCCCGAACTCCAATGCAAGGGGTAGTCATCACGAAC
+ACGTTCGTATATTATTTCTATATTTCCCTGTCGTTTGGATGCGGGGCTATCCATAGTAAT
+AACTGTAGCGAAGTTTTGTGAAAACCCCGAACATAATAGAGAGGGGGCTTTGTTAGGATC
+AAGGAAGTTCTCTGTTTCTTTCATACCCCCACTTCTAGTTTTGGGGAAAAGTTGATTGCC
+ATATACCGGGTTCCTTTAATCTCTACCCTATCGTCCCCAATTGGGGTTCACCATATTGTT
+AAATATCACTTTCCTTTCTACTTTTCCCTCACTTGGGCTCTCGGGGATTGTTTTGAAATC
+AGGTTGAACATATTTTTGTGTATGACCCATCCAAACATTTGCGGGGATAAGGCCGCCAAT
+ATTTCCTGTATCATTTTCAGTAACACCCCCGCTGAATCCATAGGGGAAAGTACTCATATA
+ATCTTTTGTATCAATTTAATTTCTTCCCTAGCAATCAGATATGGGGGCTACTTCATTATC
+AGGTAGTTGCAACTTTTCCTTAAAGCCCGAACGCCAGGCTAAGGGGCTTTTGTTAGCACC
+ATCTTCGCTATAAATTTTATATTGACCCGCACTGGTACCTTTGGGGCTAATAACTAGCAG
+ATTTTTATTGTGATTTTTATCATCGCCCAAACTATAAAATACGGGGTTGTGCATGCCATT
+ATCTTTATCATAAGTTTCTAAATCACCCGTTCTTACTGTAGTGGGGCTTCCAATATCTGT
+AGTACCGGTTTTAATTTTAATATCACCCTCTCCGGCATTAGCGGGGGGATTCATTAATAT
+AGAACCTAGCAATATTTTTGTTGTTCCCGAGCTGACTATACGGGGGTTCATTTTCATCAT
+ACTTCTATTTTTTTTTTCGATTTGACCCAACCATAATCAATAGGGGAATTTAGAATATTG
+AAGTTGAGACATATTTTATATTTATCCCCGTCTATATTAGTAGGGGTAATGTAGCAACTG
+ATAAATTACTGAGTTTTGATGAGTGCCCATTCTAAGAATATGGGGGTAACTTTTATTTAA
+AATTTGAAAGGAAGTTTTTCAATTTCCCGGGCTAGTCAAAGTGGGGTAAATTCTTTATGA
+AACAAGGAAAAGACTTTGCTAATTTCCCTGACTAATTTCTTTGGGGCTAATGATTTGTTT
+AATTTAAAAATGTATTTGATTACAACCCAAACATACAAATATGGGGGAATTAAATCAATT
+AATTAACTATTAAATTTAAATTAAACCCATACTAACTACTGTGGGGTAATAAATAGAAAT
+AGAGAAAAAGGGTATTTATTATGTTCCCAATCTCGTCGGGAAGGGGTTTTGCCATTACAT
+AGAAATATCTAATATTTAATGAAAACCCATCCTATGTATTTTGGGGATAGTGTAAAATAT
+AATATGTAAAATAATTTGTAGATTTCCCGTTCGAGGCATTATGGGGAAATTTTGAGTATA
+AGTTAGCTTTTAATTTTGAATCTTACCCAAACTTGATTAATAGGGGTATGATAGGGGATT
+AAAATGAAACTATTTTTTATCGTATCCCTTACTATTATATGGGGGGATATATTTTTAGGA
+AATGAAATTATCCATTTACTGACTGCCCTAACAACAACATTGGGGGTTGTTAATTCAAGA
+AAGGGGATTAAAAATTTCAGAGTTGCCCAATCTTATAAACTCGGGGCAATCTTTGTTTGA
+ATCTGAATCAGGCTTTTAAATTTCGCCCAATCCAGGAGTTCCGGGGCAAACAGTACAAGA
+ATTAAGAAATGGGATTTCCAAACTACCCGATCCTAGATTTAGGGGGATTATTAAACTTTA
+AAGTTACTATGTCTTTTTAAAAGAACCCTAACCATGGGACAAGGGGGTATTGCTATAATA
+ATTGAATCATTAAATTTAGGAATAGCCCCTACGACATAATAAGGGGATGTCTTAGGCTCT
+ACAATATTATATTGTTTGTAGTTGACCCAATCAAAATGACCAGGGGACAAGCATTTTTGG
+AGCCCCAACACAGATTTTGACGAAACCCCAGCTTACAATAATGGGGAAGTTGGGGATGGG
+ACCCAACACAGAGATTTTCAAAAAGCCCTTCCACAGACAATGGGGGTTGGCGGGGCCCCA
+ACATAGAGAAATTCTTTAAGAAATTCCCCAGCCAATGCAAGTGGGGGAGTGACAACGAAA
+AAAATTTTATAAAATTTCATTTCTGCCCCATCCCTACTCCCAGGGGCATTTAAATATATA
+AAAAATTTCACCTATTTTATACATCCCCCACCTTAAAAATTAGGGGTTAAATAATCTGAT
+ATGGAATTAAAGTGTTTGAAGTATACCCCACCTTCATATACTGGGGAAAGAGGACGTCAA
+AAGTTATTTTATTATTTTTTTTAACCCCAACCTTTGCTAGATGGGGATGTAATCTTTTGC
+ATAAATCAATAGTGTTTTTATTACCCCCACCCGTGATCTTAAGGGGACCTTTATTACGAT
+ATTCGGTATATAATTTTTTATTTTTCCCTAACGCTTCTCGTGGGGGGAAATCGATTTCTT
+ACAATGTTAATACTTTTTTATTGCCCCCGTACATTTTATGCGGGGGAATAATCGTTTGTA
+ATTTATCTTTGTATTTTACAAAAAGCCCATACGTTTTATCAGGGGGTTTTGCGGCTGGTG
+AAACGCCACCTGTATTTGTCTCTCTCCCAGACCACCATAACTGGGGAGTATCTTTGTCTT
+ATAGTCCAAACACATTTACGTAACGCCCTTTCAACTGATTAAGGGGTCCCCAACTTTCAG
+AGCCCCATAAAGATTTTTGTGCTGACCCTGACTATCTCTTAAGGGGAACATAAATGTTTC
+AATTATCATATTGATTTAGCCATTTCCCTGACAATGAAAAATGGGGCTGTGTGTAATATT
+AAATTAATTCATTGTTTTTAGTTTCCCCTTGCCCAATGCTATGGGGTTTAGCTTCAGAGT
+AAAAACTAAATACTTTTTTTTGATTCCCAGGCAATACAGTACGGGGTAGTAATAATGTTG
+ACGTTAAAATTATATTTTTCGTGATCCCCTTCCTCATTAGAAGGGGTCCTTTCAGAGGAA
+ACATGATACGAGGATTTAGAAATTTCCCTGTCAGCGAAGTCAGGGGAGTATTTGCGATTA
+ATTTTATTAACTCCTTTATTATTGTCCCTTTCATTTTTCGAGGGGGACTTCAATTTTTGC
+ATTTTGAGGTTTTTTTTCATATCTACCCGCACCAGTTGATGGGGGGCTTTTACTTAAATC
+AATTGTGTAGTTATTTTCTGTACCTCCCATTCTAATTTGTCCGGGGTTATAAGAATTATT
+ATATAATTTTTTACTTTTAATTAATCCCTGACGAATACGAAAGGGGAATTCTTTTAAAGT
+AAAAACAGGCTTATTTTCTTCATAACCCGGACATCCGCCAGTGGGGGTTTCTGCTTTATC
+ATTATATGTTACATTTTGTTTATAGCCCTTACCGTTAGATGTGGGGGCAGGAGTAACACC
+ACCAGTAAACGTTTTTTGAGATAATCCCAAACAATCAATGGTGGGGTGGTCTTTTATGCC
+AAAAATATCAACGCTTTTATTTCTTCCCTGGCTGATATTGCCGGGGCTTTCAGGTCCATA
+AACTTGAATATGACTTTACCAAGAACCCTGTCACAACGTTGCGGGGATCGTACCGTTATC
+ATTTTGCCATAACGTTTTGTTAGAGCCCGTTCAATATTTTTGGGGGTAATATTTAGTTAA
+ATCATTAACGTTAGTTTCGTTTTGACCCATACAATAAGCTTTGGGGTCAGATGAAGAATT
+AATAGGTGTATTAGTTTATTGTGTACCCGCTCTACCTAATAGGGGGAATGTTGTTGATAA
+AATAATTTTTTTCGTTTTGTTATTGCCCATTCGAATTTCTCCGGGGAGTATTGTTGGAAT
+ATTTAATTATAAAATTTGGTTAATTCCCTAACTGAAATTATCGGGGTTTACAAAAGGTAA
+AAGGTTAGTTAGATTTTTCGAGTATCCCTTCCATTTGTGCATGGGGAGGATTTTTAACAT
+AACGGTTTGTGTCATTTAATTTTAACCCTTTCCTTAAATCAAGGGGGTAATTATTTCCAT
+AAGCAGTTATCTTATTTTGACCTTTCCCAAACTCTCCGTTATGGGGCTTTTTATTCTTTA
+ATAATGTTTGACGATTTCGGAAATCCCCTTCCTTTAAAGTTAGGGGTGGTTTATTTCCTT
+AGTAAAATTCATGTTTTCCGATGATCCCTTGCTGTTTATCACGGGGTTTTAAAAATAGTC
+AATAAGGTTTATCATTTGAAGTAGCCCCTGGCGTAACACCACGGGGAAATGTTTCATCAT
+AAGTCCAGTAACCTTTTACTGTGTCCCCATCCTTAGTTCCAAGGGGATCAACGTATTTAT
+ATCTTAACTGATTATTTTTTCCCCACCCCTCCGATCCAAACAGGGGAATATGACTATACC
+AAACCCACGTTTGCTTTGTTGCATGCCCGCTCCCATTGGGCTGGGGCCATAGCCATTTTC
+AAGATAATGAAAAATTTGGCTGAGTCCCATACTTGATTAACTGGGGGATATTAGTCTCGT
+ATTCACTGATATTATTTGCTTTTGCCCCAGACGAAAAACTGAGGGGTGTTTTAGGAAGTT
+ATGTTGATGTGGTTTTTAAAAGTAACCCTGCCGTTGATAAAAGGGGTTTATTCATGATGT
+ACTTTTTCATATGATTTTCTCCTTTCCCTGACTTACCCAAAGGGGGTAAGCTATTACACC
+AATTCGGAATTAAATTTAAGCTAAACCCATGCTAAATAAACTGGGGCAGTTAGTAGTGTT
+ATTTAAGCAAAACTTTTCATTTTTACCCTTTCGACAGAAACAGGGGTTAATAAAGTAGGC
+AGGAGTTATATATTTTTAACGACACCCCACACTTATTCTCTAGGGGATTGCATTAAATTG
+ATTGATAATTGAATTTTCTAACTACCCCAAACATAGTTATACGGGGAATGTAGTACTTAT
+ATTAATTATTTCCTTTTACTTAAATCCCATACTAATAAAATGGGGGTTTAATTATTGATA
+AAATATTACAAATTTTTATAGTAGGCCCTGTCTATTTTGTATGGGGTTACAATTTAGGTG
+AAACTAAAATAAAATTTGTTGTTATCCCTGACAAATTTACGAGGGGGAAGTTTTTTAACT
+ATATTAGACTTTTCTTTACAAGAGGCCCAATCCTTATTAACAGGGGCCGAGGATTTAAAA
+AGTGCTAAATATATTTTCACTGAAACCCCTACGTTAAAAAATGGGGATATTGCACTGTTA
+ATTGAAAAAGATTCTTTAAGAACGCCCCGTGCATTTGAAGTTGGGGCGCATGATCAAGGT
+ACAAATGTAACTTATTTAGGCCCAACCCGATCACAAATGGGTGGGGAAGAAACAACTAAA
+AATACTGCACGTGTTTTTGGTGGAACCCATGCTGGCATTGAAGGGGGTGGTTTTTCACAA
+AGAACAGTAGAAACTTTAGCTGAAACCCCAGCCGTACCAGTGGGGGATGGTTTAACTGAT
+AAAGATCATCCTACTTTAGTTCTTGCCCATTCCTTAACAGCAGGGGAAGTCTTAAAAAAA
+AATTATGCAGATATTTTCTTTACATCCCTTGCAGATGGTCGTGGGGACGTTGCAAATGCA
+ATAATGCAAGGTGCTTTCATTATGGCCCTGACCTTCCATTTAGGGGGTCCAAAAGAATTA
+AATCCAACAGATGATTTATTAAATCCCCGTACAAATATTGCCGGGGAAAATGGTGGCAAC
+ATATTAATCACAGATTTTATTGACCCCCGTGCAAAAGGTTCGGGGGTAATTTACACTGAT
+ATTTGGGTATCAATTTTTGAACCTGCCCAAGCATGGAAAGAAGGGGTTGAATTATTGAAA
+ACATATCAAGTAAATTTAGAAATGACCCATACAACTGGTAATGGGGATGTTATTTTTGAG
+AATTGCTTACCATCTTTCCATAATGCCCATACGAAAATTGGTGGGGAAATTTTTGAAAAA
+AATGGTATTCGAGATTTGGAAGTTACCCATGCAGTATTCGAAGGGGAAGCTTCAGTTGTA
+ATCCAAGAAGCTGATTTCAGAATGCCCCCAACCAAAGCAGTCGGGGTTGCTACATTGGGT
+AAATTTTAAATGATTTTAGGAAGTGCCCATGCTGGCGAAAATGGGGGTAGCATTAGGTGG
+AAATGCTTTAGGAATTTCACCTCAACCCCAACTCGAGCTTGTGGGGAATACTGCGAAATC
+ATTAGTAGGATTAATTTCAAAAGGACCCGAGCTTGTTATTAGGGGGGGTAATGGACCACA
+AGTTGGAAGCATTATTTTGGGACTTCCCTATCCTGCAGAACAGGGGCAAGGTCCGGCATT
+ACCATTTGCTGAATTTTGCGCAATGCCCCAACCTTACATCGGGGGGCAATTACAAGAAAG
+ATTACAAAATGAATTTTATTCTATTCCCATGCATAAACAAGTGGGGACACTAGTGACACA
+AGTTGAAGTTGATGTTTATGATCCGCCCTTTCACAATCCTTCGGGGCCAATTGGGTTATT
+ATACAACAAAGAAGTTTCTGAACAACCCCAACAAGAAAAAGGGGGGATATTTGTTGAAGA
+AGCTGGAAGAGGATTTTGACGCGTTCCCCCTCCACCACAACCGGGGTCTATTATTGAATT
+AGAGAGTATTAAAATTTTTATTAAACCCGATCCACTCGTTATGGGGGCTGGTGGTGGAGG
+AATACCAGTAATTATTTAGCAACATCCCGGTCTTAAAGGTATGGGGGCAGTTATAGACAA
+AGATAAAACAAGTGTTTTGTTGGGTCCCAATCTTCAATGCGAGGGGTTGATTATTTTAAC
+AGCAATTGATTATGTTTATATTAATCCCAACCCTGAAAACCAGGGGCCTTTGAAAACAAC
+AAATGTTGATGAATTTTAACGATATCCCGACCAAAATCAATTGGGGAAAGGAAGTATGTT
+ACCAAAAATTGAAGTTTCCATATCACCCATTCAAAACAATCCGGGGGGAAGTGTGCTTAT
+AACATCATTAAATGTTTTAGATGCTCCCTTACAGGGTAAAGTGGGGACTGTGATTAAAAA
+ATAATTGAATTGAATTTCTTTTCAACCCCTACATGTCAAATGGGGGATTTTTATTATTTA
+AGTGCACCCCCTGATTTTAATGCCTCCCTTTCGATGCGGGGTGGGGTTTCTTAATTTATA
+ATTATAAAATCTTTTTTGTAGAAATCCCAGGCTAAATGTCGAGGGGGATGAAACCGTGGA
+AAATACAATTAATGTTTGTGAAAAGCCCAAACGATTTAAATTGGGGATGCCAGGTGCATT
+AATGATTTTATTCATTTTAACGGTTCCCGCACTTATAGCAACGGGGGTTATTCCTGCTGG
+AGCATATTCTAAACTTTCTTACGAACCCTCACCCCAAGAACTGGGGATAGTTAACCCTCA
+AAACCAAGTGAAAATTTTTCCGGGTCCCCAACAGGAACTAGAGGGGATGGGGGTTAAAAT
+AAAGATTGAACAATTTTAATCAGGTCCCATTCATAAGCCAGTGGGGATTCCGAATACTTA
+AGAAAGATTAAAGCTTTATCCAGCTCCCCCACAACAAATAACGGGGAGCATGGTTGAAGG
+AACGATAGAAGCGGTTTATATCATGCCCTTCCTTCTTGTACTGGGGGGACTTATTGGCGT
+AGTTCAAGCCAGTGTTTCTTTTGAACCCGGACTGTTAGCTTTGGGGAAGAAAACAAAAGG
+ACATGAATTTATGCTTTTTGTGTTTCCCTCACTACTAATGATGGGGGGCGGGACGTTATG
+AGGTATTGAAGAAGTTTCTGTAGCACCCTATCCGATTTTAGTGGGGATATTTATAGCGTT
+AGGATACGATTCTATTTTTTCAGTTCCCGCCCTATTCCTTGCGGGGTCTGTCGGTAGTAC
+ATTTTCAACTATTATTTCGTTCTCGCCCGTACTTGCCTCTAAGGGGGCTGGTACAACTTT
+AACGGATGGCTTGTTTTGGAGAATACCCGCTCGTATTGTCGGGGGGATTTTTGTTATTAG
+ATATTTATATTGGTTTTGTAAAAAACCCAAACACGATCCTAAGGGGTCATATTCTTATGA
+AGACAAAGATGCTTTTTAACAGCAACCCTCTCTATTAAAAGAGGGGGATAGTGCCCATTT
+AACTTTGCGTAAGATTTTAATCCTTCCCTTACTTGTACTACCGGGGCCAATTATGGTATG
+AGGAGTTATGACGCTTTGTTGGTGGCCCCCACTTATGGCTTCGGGGTTTTTAATATTTAC
+AATTATAATAATGTTTTTTGCTGGGCCCGGTCAATCTGGATTGGGGGAAAAAGGAACTGT
+AGATGCATTTGTCATTTGTGCATCACCCTTACTAGGTGTATCGGGGATTATTGGTTTAGC
+ACGAGGTATTAATTTTTTGTTGAATCCCGGTCTGATTTCAGAGGGGATCTTACACTTTTC
+ATCATCTTTAGTTCTTTATATGAGTCCCCCACTATTTATCATGGGGTTACTATTTATTTT
+ATTCTGTTTAGGTTTTTTCGTGCCACCCTCTCCTGGATTAGCGGGGTTATCAATGCCTAT
+ATTTGCACCACTAGTTTATACAGTACCCATACCAAGATTCGTGGGGGTTACGACATATCA
+ATTTGGTCAATATGTTTTGTTATTCCCCGCGCCGACTGGACTGGGGATGGCCACACTACA
+AATGTTAAACATGCTTTATTCACATCCCTTCCGATTTGTATGGGGGGTAGTTGCTTTTGT
+ATTGATTTTCGGTGTTTGAGTACTACCCACGCAAGTACTAATGGGGTCATAATTTGAAAT
+ACTATATTATAAAATTTCTAATTGGCCCTTACGCATCTCGTAGGGGTGTAGAAATACTAA
+ACTAAGCGAGGTGCTTTATTATTTTCCCTTACGAAAATAATGGGGGTAATGATAACACTA
+ATAAGTAATTGATATTTTGCTCTATCCCATACTGATATTTTTGGGGTTTGTTTTTAATGT
+AATGTTAGATCTATTTTATATTATACCCATCCTGGTAAATATGGGGTTGCTGTAAACAGT
+ATTTGTAACACATGTTTCATATGGTCCCGAACATAGCATATAGGGGGGATGGCTATAAAT
+AACACATTTGACAATTTTTTTAGATCCCCTACCTGGAATATGGGGGGTATTATTATTTAG
+AAAATATTTTGTGGTTTATGCAAATCCCGTGCTTGATTGGAAGGGGAGATGGTATTTGCT
+AGAAAACATACCACTTTTGCCAATTCCCTTACTTATTCTGATGGGGATTTTCGGAGTACC
+ATCTGAAATGATAATTTATAGGCAACCCAAACATAACGGTGTGGGGTTTATCGATATTTA
+AAGGTGATAAAATTTTTCAACTATTCCCAAGCCTAAAATAAAGGGGTTTATTAATTATTT
+AATTGGTATATTAGTTTTGGCGTTTCCCGCTCATATATTATTGGGGTAAAGGTTAGAGTG
+AAACGTGTTTATGATTTAGACGTTCCCCTATCGTTACTACAGGGGGAGTCAGAAGGTATC
+ATTGATAAGATCATTTTAAATCAAACCCGCACTGATATACACGGGGAAGAGGCAAGATTA
+ACTGCCTCTTTTTTTTTTATTAAATCCCCGTCTTAATTCTTGGGGGTAGTGTTACTGAGA
+AGCATTACGAAGAATTTTATCTTGACCCTCCCTTTTTAAAAAGGGGTGAAGATATCCTAT
+AAAGACTCTAAGTATTTTTACAGTGCCCAATCACACTTCGATGGGGAAAAGACCTTTCCA
+AATATCTGGAAACATTTGTACAGGCCCCCTGCTCTTTAAAGCGGGGGCTGAGATTACTAA
+AGGGAATGTGAAAGTTTAAAATACGCCCGAACAAGGTTCTTTGGGGAATTTAGGCAATTG
+AATAATGATATAAATTTAAAATATTCCCGCTCATATTAAAAAGGGGATTACGATAAAAGC
+ATTCGCCTTAGGAATTTCTATAACACCCGCTCCAGCGACTAAGGGGAATGGTGCACAAAT
+AGTCGATGTGTTCGTTTTGATTGACCCCTGCCATGGAAATGCGGGGAATCGCTTGAAAAC
+AATAGGTAAGACAATTTAAGTAGCTCCCAAGCCATATATTACGGGGAATTGACCTATGAA
+AAAACATCCGCTAATTTGTGCCGTCCCCCCTCCGATAGCAATGGGGATAAAAAGTACAGT
+ACACGAAGGATAAATTTTTTCAAGTCCCAAACCTTTTAAATAGGGGATTGAAAAAATAAT
+AATATGCGTCATAATTTCCACAAGGCCCAAACTCCAAATAGGGGGGATTAAGCTATTGAT
+AAAAGTTATGTTACTTTAAAATGTACCCAAACAAGTAGTACCGGGGAAGCCAGACATGAA
+AAATGTTGTGAACATTTATGAAACTCCCGGACTGTTTAATTGGGGGTTCACATTATTAAA
+ATATTTGATCATAGTTTATAAAAGGCCCATCCAAATCAAGAAGGGGAAGATTCCGCAAAC
+AGCGTTTAAAGTAATTTATAAGTCTCCCAATCGATTACCCAGGGGGAATAATCCTAAGAC
+AAGTCCTGACGTTATTTGAGGTGCTCCCTGACGTCTCATGATGGGGAACCTTTCTTATGT
+AATTTTCTTCACTATTTATATCATGCCCGCTCTGGCCAATTAGGGGGAAGAGTGTGTACT
+ATTACGTTATTAGATTTTGTATATTCCCTTGCTAGACACATAGGGGACATTTAAATCTCA
+AAATTAATGATATTTTTGGTATGCTCCCCAACCTAAATATTGGGGGATGTGGAAAAGTAA
+ATATTTAATTTAAATTTTGATTGAACCCTTACAAGGGGGTGTGGGGAATGAGAAATCAAA
+ATCAAAAACTATTATTTAGTGATTTCCCCAGCTTACATATATGGGGACAAACAGGAGTTC
+AACAAAGCACAATATTTAGAATGAGCCCAAACGAAAGATCATGGGGCAATATGTCATTGA
+AAAACGCTGAACTATTTTATAAATTCCCCAACAGTATATTTAGGGGTGAAAATTAAGAAG
+AATAATTAGTGAGTTTTATAATTAACCCACCCCGTCTCGATGGGGGTGGTTATTTTTTTA
+AATGTATTTAATTATTTGATTTCGGCCCCCTCAAAAGTCCCTGGGGTTTTGAATAGTATC
+AAAATCTATAGGAATTTTATAATAACCCAAACCTCTACGCATGGGGATGGTGAGTGTTAA
+AAATCTTGGTGTAGTTTTGGTGTAGCCCAGGCGCAGTATAGAGGGGATTTGAGCACAAAA
+ATACTTAATTAAAATTTTATAAACACCCGTCCGACGCGTGTCGGGGGTGTGTCAAAAAAT
+ACTATGACGAATAATTTTGCTTGTTCCCATTCCTGTATTTTCGGGGCTTATGCGGGGGAC
+ATTTTGGTGACGCATTTTACTATATCCCTGACATTCAAAACAGGGGGAGCCCCGTAATCA
+AGGAACTCTTTTGTTTTGTAATGCGCCCAAACATACCTATAAGGGGCCTGGGAGGGATTC
+AAACCCCCGACCGATTTCTTAGAAGCCCATTCCTCTATCCAGGGGGGCTACCAGGACACG
+ATTAACAACACAAGTTTTATTATATCCCAATCAACTTAAATTGGGGATACCTTGTAAATA
+AAAAATGTTTATATTTTTCACTATTCCCGAGCTATTTATCTAGGGGGGTTCAATAAGACT
+AAAATGCGAATTCATTTAACTTAATCCCGTTCAATACAGTTTGGGGTGCCTAACTGTATT
+ACTTTTCTCTTTAATTTACAGTTAACCCCATCATAAGATGTTGGGGGGATAAACAAACTA
+ATTGCATCAAATTTTTTTTAAAATACCCACACCAAAACGTTAGGGGAATAACATTTCGGT
+AATTTAAAAGCTACTTTCGTTTTTGCCCTCTCCAAATTTAAAGGGGAAGGAGTGTTTTCA
+ATGGAAGGTTTATTTTTCGCAATTACCCATACCGTAACTGCAGGGGTTAATAATGATGGC
+ACAAAATTAGGCACTTTCATTGTGACCCTCGCTGAAAATGGCGGGGGTTTATTAGGTAAA
+ATATTCGGATTCTATTTTCAATATGCCCTGTCAGTAATCAGTGGGGTTTCAAAGGTGAGG
+AAGAGATTTAAATGTTTGGACTAGCCCCAGCCATCGCAAATAGGGGGCAAGCTGCACAAC
+AACATGATAGTGTGTTTTTAGGCACCCCTATCGTAGACATCGGGGGTAACGGTGTGGGTT
+AACTAGGTAAATTATTTGGATTCTACCCTAACAACTAATATTGGGGAAAATAAACTGGGT
+AAGCATACTTTAATTTTATGCACTCCCCTTACTTTATTTGCAGGGGTTTGAGCCTCTGTT
+AAGATTTAGATACATTTACAATATACCCGATCGGGAAATTGGGGGGTAAAAATATTTTGA
+AAGACTTTGATGATTTTATTGTTGACCCTTACGATGCAGAAGGGGGGGCGTTTCACTATA
+AGGCGAATGTTTTTTTTCATAAAGCCCCAAACGATGATTTTTGGGGATTTAAAAAAATCA
+ATCACCAACATTGGTTTGCTTTTCACCCAAACAAATTAACGAGGGGTGAAGTATTATCAG
+AACGATTTGTGAATTTTTTCAAACACCCTCACATGGAAGTTGGGGGGCATCGTGCAGATG
+AGTTATTTAGAAATTTTTTAGCAGACCCTAACGTTAAATACTGGGGTCAAACATTAGAAA
+AAATTGTCGAATTATTTAAAAGACACCCTTTCTATATTGTTAGGGGTGGTGTAACCGAAA
+AGCAAAAGAGAAGGTTTAATCAGACCCCGTTCCATAAATATAGGGGAAAGATATTTATAT
+ATGAGGAAACAGGATTTCAAAAACCCCCTCCCGAATTTTTTAGGGGTGTTTTTAATGATA
+ATGGTGAGGATGAATTTCAGCACTCCCCTATCGTTGGAGATTGGGGAACATCTGACATTC
+AAGGTGGAATCAATTTTGGTATAGCCCCTTGCTGGTTTAATTGGGGAGGATTTGATCATA
+ATCCAGGAATTATATTTGATTATGACCCTAACTCATGGAAACGGGGAAATGATATTGTAC
+ATTAAGACAAATAATTTGAAAATGACCCATACTAGCTTAAGAGGGGAATTGTAAAAACGA
+AACTACGAAAAGATTTTTTTTCATGCCCGTACTGTCGAATATGGGGATCTTATGGTTTCC
+ACAATAAGACATCATTTCCCTCTATCCCTTTCGCTTCCACATGGGGAAATCCATGATGTA
+AAAAGAAATCCTTATTTTCATTTCTCCCAATCGCTTTAATTGGGGGATTGAAACTCTTTG
+AAAAATCAATCAATTTTGAAGCGTACCCTCTCTTTTGATATTGGGGTAATACTTCTAACT
+ACCATAATAATATATTTTCTTCAAACCCTGGCAAGTAGATTTGGGGGACATCACCTTTTT
+ATAGTAATGCCATTTTTGCTCCTAACCCATCCCCGACAAATAGGGGATAAAATGGTGAAT
+ATGAACTTGCATCATTTATTTGACCCCCTAACTCATTGACCAGGGGTAAGTCTTTGTTGC
+AAAACGCTCTAAAGTTTTCGAATAACCCGTCCGTTTTGTAATGGGGTTCAAGACGTTTGA
+ATTCACTCATATTTTTTTACCCCTTCCCTGTCTACTACTATTGGGGTACATTAAACCACT
+AGTGTTTTTCATTGTTTTGAAAATGCCCAACCATGAACATTAGGGGTTTTCCATGATTAA
+ATTGATTTTCAAGCTTTAAAATTGTCCCTCACCGGTATAGACGGGGTACTATAGTTTGTA
+ATCGCGTACTTAAGTTTAAAAAACACCCACTCTAAAGTAGTTGGGGTAAATGAAAAAGAT
+AAGTTTATACCAAATTTAAAGAGCACCCACCCTGTAATAACAGGGGTATTTCAATATGAT
+ACAGCTCAACAAACTTTTTTTGAAACCCGGACGTCTAAAGAAGGGGATGGAAGAGAAGCG
+ACATTAGCGAATGTTTTTCGTGAATCCCTGACTGATTTAAAGGGGGCAAATGAACAAGAA
+ATAAACATACAACATTTAGCTAATGCCCCAACAGTTGTGATTGGGGGACAACAAGCAGGG
+ATTTTCGGGGGACCTTTGTATACATCCCATACAATATTTTCAGGGGTTACTTTATCTAAG
+AAATTAACGGATACTTTTAAGCAACCCCTAGCACCAGTTTTTGGGGTTGCAGGAGAAGAT
+AATGATTTCGATGATTTGAATCATACCCTTGCTTATAACGAAGGGGATGGGTCGCTGCAT
+AAGGTTAAATATCATTTAATGGAGACCCCAGCGACGACAGTCGGGGGATATTATCCTGAT
+AAGGCTGAGTTGAATTTAACTTTAACCCCGACGTTCATTCATGGGGAAGAAACTGTTCAT
+ACACAAGGTCTACTTTTGATTTGTGCCCGAACTATTGACCAAGGGGACTCGTGGACTGAT
+ATGTTTAAAGCACTTTTGCATGAAACCCTTACAGCATATGGCGGGGTATTTATAGATGCG
+AAGTTTGAGCCGTTTTTAAAAATGGCCCCGCCTATGTTTAAAGGGGTTTTGAAAAAACAT
+AAGTTGCTTGATGATTTTTTTAGAGCCCCACCACAACGTACTGGGGATCAAGGCTTGAAT
+ACGATGATACAAACTTTTACAAATGCCCATTCATTCTTACATGGGGAAAATATGCGCCAA
+ATAGTTTCGTATGATTTTAAGCATTCCCAATCAAATAAAACAGGGGAGACATATATAAAG
\ No newline at end of file
diff --git a/t/data/query_groups b/t/data/query_groups
new file mode 100644
index 0000000..bdbb4a1
--- /dev/null
+++ b/t/data/query_groups
@@ -0,0 +1,7 @@
+group_1: 1_1 2_1 3_1
+group_2: 1_2 2_2
+group_3: 1_3 3_3
+group_4: 2_4 3_4
+group_5: 3_5
+group_6: 1_6
+group_7: 2_7
\ No newline at end of file
diff --git a/t/data/query_groups_all_merged b/t/data/query_groups_all_merged
new file mode 100644
index 0000000..c4815ee
--- /dev/null
+++ b/t/data/query_groups_all_merged
@@ -0,0 +1 @@
+group_1: 1_1 2_1 3_1 1_2 2_2 1_3 3_3 2_4 3_4 3_5 1_6 2_7
\ No newline at end of file
diff --git a/t/data/query_groups_missing_genes b/t/data/query_groups_missing_genes
new file mode 100644
index 0000000..616fa8b
--- /dev/null
+++ b/t/data/query_groups_missing_genes
@@ -0,0 +1,7 @@
+group_1: 1_1 2_1 3_1 4_1
+group_2: 1_2 2_2
+group_3: 1_3 3_3
+group_4: 2_4 3_4
+group_5: 3_5
+group_6: 1_6
+group_7: 2_7
\ No newline at end of file
diff --git a/t/data/query_groups_paralogs b/t/data/query_groups_paralogs
new file mode 100644
index 0000000..6661bde
--- /dev/null
+++ b/t/data/query_groups_paralogs
@@ -0,0 +1,6 @@
+group_1: 1_1 2_1 3_1
+group_2: 1_2 2_2 2_7
+group_3: 1_3 3_3 2_4
+group_4: 3_4
+group_5: 3_5
+group_6: 1_6
diff --git a/t/data/query_groups_reference b/t/data/query_groups_reference
new file mode 100644
index 0000000..62c6032
--- /dev/null
+++ b/t/data/query_groups_reference
@@ -0,0 +1,6 @@
+group_1: 1_1 2_1 3_1
+group_2: 1_2 2_2
+group_3: 1_3 3_3
+group_5: 3_5
+group_6: 1_6
+group_7: 2_7
diff --git a/t/data/raxml.tre b/t/data/raxml.tre
new file mode 100644
index 0000000..ba35f18
--- /dev/null
+++ b/t/data/raxml.tre
@@ -0,0 +1 @@
+((efgh_7#3:0.02316815548247504186,(((((abcd_4#15:0.00000132226186997362,((abcd_3#9:0.00077142536151366802,abcd_4#17:0.00231509323793084891)66:0.00000132226186997362,abcd_3#20:0.00000132226186997362)69:0.00000132226186997362)100:0.00465923394294907780,abcd_3#96:0.00855943508912884905)97:0.00305706239572176106,abcd_3#7:0.00702776231555758951)100:0.01189241259037208259,((6753_5#30:0.00077274606169234225,((abcd_3#8:0.00232303086183083740,abcd_3#12:0.00000132226186997362)15:0.0000013222618699 [...]
diff --git a/t/data/real_data_1.gff b/t/data/real_data_1.gff
new file mode 100644
index 0000000..9b1b4c1
--- /dev/null
+++ b/t/data/real_data_1.gff
@@ -0,0 +1,1641 @@
+##gff-version 3
+##sequence-region ERS111111|SC|contig000020 1 92255
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 241 921 . - 0 ID=11111_1#11_04055;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002145956.2,protein motif:Pfam:PF07108.5;locus_tag=11111_1#11_04055;product=pathogenicity island-encoded protein A,PipA protein;protein_id=gnl|SC|11111_1#11_04055
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 1144 2019 . - 0 ID=11111_1#11_04056;gene=pipB2_2;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002145957.1,similar to AA sequence:UniProtKB:Q8ZMM8,protein motif:CLUSTERS:PRK15197,protein motif:Cdd:COG5351,protein motif:Pfam:PF00805.16;locus_tag=11111_1#11_04056;product=secreted effector protein,Type III effector pipB2,secreted effector protein PipB,Uncharacterized protein conserved in bacteria,Pentapeptide repeat [...]
+ERS111111|SC|contig000020 Infernal:1.1 ncRNA 2139 2237 . + 0 ID=11111_1#11_04057;inference=COORDINATES:profile:Infernal:1.1;locus_tag=11111_1#11_04057;product=isrI
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 2567 2908 . - 0 ID=11111_1#11_04058;gene=sigE;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002145959.1,similar to AA sequence:UniProtKB:O30917,protein motif:CLUSTERS:PRK15202,protein motif:Pfam:PF07824.6;locus_tag=11111_1#11_04058;product=chaperone protein SigE,Chaperone protein sigE,type III secretion chaperone protein SigE,Type III secretion chaperone domain;protein_id=gnl|SC|11111_1#11_04058
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 2925 4610 . - 0 ID=11111_1#11_04059;eC_number=3.1.3.-,3.1.3.-;gene=sopB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002145960.1,similar to AA sequence:UniProtKB:O30916,protein motif:CLUSTERS:PRK15378,protein motif:Pfam:PF05925.6;locus_tag=11111_1#11_04059;product=inositol phosphate phosphatase SopB,Inositol phosphate phosphatase sopB,inositol phosphate phosphatase SopB,Enterobacterial virulence protein IpgD;pro [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 5332 6801 . - 0 ID=11111_1#11_04060;eC_number=3.4.-.-;gene=pepD_2;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002215025.1,similar to AA sequence:UniProtKB:Q8G6Z9,protein motif:Pfam:PF03577.9;locus_tag=11111_1#11_04060;product=peptidase family C69,Dipeptidase,Peptidase family C69;protein_id=gnl|SC|11111_1#11_04060
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 6974 8338 . - 0 ID=11111_1#11_04061;eC_number=2.7.13.3;gene=yedV;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002145964.1,similar to AA sequence:UniProtKB:P76339,protein motif:CLUSTERS:PRK09835,protein motif:Cdd:COG5278,protein motif:TIGRFAMs:TIGR01386,protein motif:Pfam:PF02518.20;locus_tag=11111_1#11_04061;product=heavy metal sensor kinase subfamily,Probable sensor-like histidine kinase YedV,sensor kinase CusS [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 8331 9068 . - 0 ID=11111_1#11_04062;gene=copR;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002243090.1,similar to AA sequence:UniProtKB:P76340,protein motif:CLUSTERS:PRK11517,protein motif:Cdd:COG4565,protein motif:TIGRFAMs:TIGR01387,protein motif:Pfam:PF00072.18;locus_tag=11111_1#11_04062;product=transcriptional regulatory protein YedW,Probable transcriptional regulatory protein YedW,transcriptional regulatory [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 9147 9557 . + 0 ID=11111_1#11_04063;eC_number=3.5.2.17,3.5.2.17;gene=uraH;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002145966.1,similar to AA sequence:UniProtKB:Q4VYA5,protein motif:CLUSTERS:PRK15036,protein motif:TIGRFAMs:TIGR02962,protein motif:Pfam:PF00576.15;locus_tag=11111_1#11_04063;product=hydroxyisourate hydrolase,5-hydroxyisourate hydrolase precursor,hydroxyisourate hydrolase,hydroxyisourate hydrolas [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 9890 10402 . - 0 ID=11111_1#11_04064;eC_number=1.5.1.36;gene=hpaC;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729827.1,similar to AA sequence:UniProtKB:Q57501,protein motif:CLUSTERS:PRK15486,protein motif:TIGRFAMs:TIGR02296,protein motif:Pfam:PF01613.12;locus_tag=11111_1#11_04064;product=4-hydroxyphenylacetate 3-monooxygenase coupling protein,4-hydroxyphenylacetate 3-monooxygenase reductase component,4-hydro [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 10420 11652 . - 0 ID=11111_1#11_04065;eC_number=1.14.14.9;gene=hpaB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002145968.1,similar to AA sequence:UniProtKB:Q57160,protein motif:TIGRFAMs:TIGR02310,protein motif:Pfam:PF03241.7;locus_tag=11111_1#11_04065;product=4-hydroxyphenylacetate 3-monooxygenase%2C oxygenase component,4-hydroxyphenylacetate 3-monooxygenase oxygenase component,4-hydroxyphenylacetate 3-monooxy [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 11833 12273 . - 0 ID=11111_1#11_04066;gene=hpaR;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002145969.1,similar to AA sequence:UniProtKB:O07458,protein motif:TIGRFAMs:TIGR02337,protein motif:Pfam:PF01047.16;locus_tag=11111_1#11_04066;product=homoprotocatechuate degradation operon regulator%2C HpaR,Benzoate anaerobic degradation regulator,homoprotocatechuate degradation operon regulator%2C HpaR,MarR family;prote [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 12548 13837 . + 0 ID=11111_1#11_04067;eC_number=5.3.3.-;gene=hpaG;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729830.1,similar to AA sequence:UniProtKB:P37352,protein motif:CLUSTERS:PRK15203,protein motif:Cdd:COG0179,protein motif:TIGRFAMs:TIGR02303,protein motif:Pfam:PF01557.12;locus_tag=11111_1#11_04067;product=4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase,Homoprotocatechuate cata [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 13834 14133 . + 0 ID=11111_1#11_04068;eC_number=1.2.1.8;gene=hpcC_1;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729831.1,similar to AA sequence:UniProtKB:Q9HTJ1,protein motif:CLUSTERS:PRK13252,protein motif:Cdd:COG3191,protein motif:TIGRFAMs:TIGR02299,protein motif:Pfam:PF00171.1;locus_tag=11111_1#11_04068;product=5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase,Betaine aldehyde dehydrogenase,bet [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 14127 15299 . + 0 ID=11111_1#11_04069;eC_number=1.2.1.-;gene=hpcC_2;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729831.1,similar to AA sequence:UniProtKB:P23105,protein motif:CLUSTERS:PRK13252,protein motif:Cdd:COG4230,protein motif:TIGRFAMs:TIGR02299,protein motif:Pfam:PF00171.1;locus_tag=11111_1#11_04069;product=5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase,2-hydroxymuconic semialdehyde dehy [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 15301 16152 . + 0 ID=11111_1#11_04070;eC_number=1.13.11.15,1.13.11.15;gene=hpcB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729832.1,similar to AA sequence:UniProtKB:Q05353,protein motif:CLUSTERS:PRK03881,protein motif:Cdd:COG0179,protein motif:TIGRFAMs:TIGR02298,protein motif:Pfam:PF02900.1;locus_tag=11111_1#11_04070;product=3%2C4-dihydroxyphenylacetate 2%2C3-dioxygenase,3%2C4-dihydroxyphenylacetate 2%2C3-d [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 16162 16542 . + 0 ID=11111_1#11_04071;eC_number=5.3.3.10,5.3.3.10;gene=hpcD;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729833.1,similar to AA sequence:UniProtKB:Q05354,protein motif:CLUSTERS:PRK15031,protein motif:Cdd:COG3232,protein motif:Pfam:PF02962.1;locus_tag=11111_1#11_04071;product=5-carboxymethyl-2-hydroxymuconate delta-isomerase,5-carboxymethyl-2-hydroxymuconate Delta-isomerase,5-carboxymethyl-2-hy [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 16686 17489 . + 0 ID=11111_1#11_04072;eC_number=4.2.-.-,4.2.1.80;gene=hpcG;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729834.1,similar to AA sequence:UniProtKB:Q9S156,protein motif:CLUSTERS:PRK11342,protein motif:Cdd:COG3971,protein motif:TIGRFAMs:TIGR02312,protein motif:Pfam:PF01557.12;locus_tag=11111_1#11_04072;product=2-oxo-hepta-3-ene-1%2C7-dioic acid hydratase,2-keto-4-pentenoate hydratase,2-keto-4-pen [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 17500 18291 . + 0 ID=11111_1#11_04073;eC_number=4.1.2.-;gene=hpaI;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_216043.1,similar to AA sequence:UniProtKB:Q47098,protein motif:CLUSTERS:PRK10128,protein motif:Cdd:COG2301,protein motif:TIGRFAMs:TIGR02311,protein motif:Pfam:PF03328.8;locus_tag=11111_1#11_04073;product=4-hydroxyphenylacetate catabolism,4-hydroxy-2-oxo-heptane-1%2C7-dioate aldolase,2-keto-3-deoxy-L-rha [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 18363 19739 . + 0 ID=11111_1#11_04074;gene=hpaX;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729836.1,similar to AA sequence:UniProtKB:P76470,protein motif:CLUSTERS:PRK11551,protein motif:Cdd:COG2814,protein motif:TIGRFAMs:TIGR02332,protein motif:Pfam:PF07690.10;locus_tag=11111_1#11_04074;product=4-hydroxyphenylacetate permease,Inner membrane transport protein RhmT,putative 3-hydroxyphenylpropionic transporte [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 19749 20645 . + 0 ID=11111_1#11_04075;gene=hpaA;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729837.1,similar to AA sequence:UniProtKB:P40408,protein motif:CLUSTERS:PRK10572,protein motif:Cdd:COG2169,protein motif:TIGRFAMs:TIGR02297,protein motif:Pfam:PF12833.1;locus_tag=11111_1#11_04075;product=4-hydroxyphenylacetate 3-monooxygenase operon regulatory protein,Bacillibactin transport regulator,DNA-binding tran [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 20659 21597 . + 0 ID=11111_1#11_04076;eC_number=3.1.26.11,3.1.26.11;gene=rnz;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_006087376.1,similar to AA sequence:UniProtKB:P54548,protein motif:CLUSTERS:PRK00055,protein motif:Cdd:COG5212,protein motif:TIGRFAMs:TIGR02651,protein motif:Pfam:PF12706.1;locus_tag=11111_1#11_04076;product=Ribonuclease Z,Ribonuclease Z,ribonuclease Z,Low-affinity cAMP phosphodiesterase,ribon [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 23021 23326 . - 0 ID=11111_1#11_04077;gene=cbpM;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_001570915.1,similar to AA sequence:UniProtKB:P63264,protein motif:CLUSTERS:PRK10265;locus_tag=11111_1#11_04077;product=chaperone-modulator protein CbpM,Chaperone modulatory protein CbpM,chaperone-modulator protein CbpM;protein_id=gnl|SC|11111_1#11_04077
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 23326 24246 . - 0 ID=11111_1#11_04078;gene=cbpA;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729840.1,similar to AA sequence:UniProtKB:P36659,protein motif:CLUSTERS:PRK10266,protein motif:Cdd:COG5407,protein motif:TIGRFAMs:TIGR02349,protein motif:Pfam:PF01556.12;locus_tag=11111_1#11_04078;product=curved DNA-binding protein,Curved DNA-binding protein,curved DNA-binding protein CbpA,Preprotein translocase subun [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 24482 24844 . + 0 ID=11111_1#11_04079;gene=scsA;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729841.1;locus_tag=11111_1#11_04079;product=copper-sensitivity suppressor membrane protein A;protein_id=gnl|SC|11111_1#11_04079
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 24893 26779 . + 0 ID=11111_1#11_04080;eC_number=1.8.1.8;gene=scsB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729842.1,similar to AA sequence:UniProtKB:P36655,protein motif:CLUSTERS:PRK00293,protein motif:Cdd:COG4233,protein motif:Pfam:PF02683.9;locus_tag=11111_1#11_04080;product=copper-sensitivity suppressor membrane protein B,Thiol:disulfide interchange protein DsbD precursor,thiol:disulfide interchange pr [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 26776 27399 . + 0 ID=11111_1#11_04081;gene=scsC;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729843.1,similar to AA sequence:UniProtKB:O32218,protein motif:Cdd:COG1651,protein motif:Pfam:PF01323.14;locus_tag=11111_1#11_04081;product=copper-sensitivity secreted suppressor protein C,Thiol-disulfide oxidoreductase D,Protein-disulfide isomerase,DSBA-like thioredoxin domain;protein_id=gnl|SC|11111_1#11_04081
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 27389 27895 . + 0 ID=11111_1#11_04082;gene=resA;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002145985.1,similar to AA sequence:UniProtKB:P35160,protein motif:CLUSTERS:PRK03147,protein motif:TIGRFAMs:TIGR00385,protein motif:Pfam:PF08534.4;locus_tag=11111_1#11_04082;product=suppressor for copper-sensitivity D,Thiol-disulfide oxidoreductase resA,thiol-disulfide oxidoreductase,periplasmic protein thiol:disulfide ox [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 28028 29269 . + 0 ID=11111_1#11_04083;eC_number=3.1.3.10;gene=agp;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_001570908.1,similar to AA sequence:UniProtKB:P19926,protein motif:CLUSTERS:PRK10173,protein motif:Pfam:PF00328.1;locus_tag=11111_1#11_04083;product=glucose-1-phosphatase/inositol phosphatase,Glucose-1-phosphatase precursor,glucose-1-phosphatase/inositol phosphatase,Histidine phosphatase superfamily (bra [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 29303 29530 . - 0 ID=11111_1#11_04084;gene=yccJ;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_006087385.1,similar to AA sequence:UniProtKB:P0AB14,protein motif:CLUSTERS:PRK10174;locus_tag=11111_1#11_04084;product=YccJ-like protein,hypothetical protein,hypothetical protein;protein_id=gnl|SC|11111_1#11_04084
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 29551 30147 . - 0 ID=11111_1#11_04085;gene=wrbA;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729847.1,similar to AA sequence:UniProtKB:P0A8G6,protein motif:CLUSTERS:PRK03767,protein motif:TIGRFAMs:TIGR01755,protein motif:Pfam:PF03358.9;locus_tag=11111_1#11_04085;product=trp repressor binding protein,Trp repressor-binding protein,NAD(P)H:quinone oxidoreductase,NAD(P)H:quinone oxidoreductase%2C type IV,NADPH-de [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 30532 30699 . + 0 ID=11111_1#11_04086;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_006087756.1,protein motif:Pfam:PF10685.3;locus_tag=11111_1#11_04086;product=Conidiation-specific protein 10,Stress-induced bacterial acidophilic repeat motif;protein_id=gnl|SC|11111_1#11_04086
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 30836 31474 . + 0 ID=11111_1#11_04087;gene=rutR;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729849.1,similar to AA sequence:UniProtKB:P0ACU2,protein motif:CLUSTERS:PRK15008,protein motif:TIGRFAMs:TIGR03613,protein motif:Pfam:PF08362.5;locus_tag=11111_1#11_04087;product=transcriptional regulator,Rut operon repressor,HTH-type transcriptional regulator RutR,pyrimidine utilization regulatory protein R,YcdC-like [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 31471 31866 . - 0 ID=11111_1#11_04088;inference=ab initio prediction:Prodigal:2.60,protein motif:Cdd:COG3755,protein motif:Pfam:PF07007.6;locus_tag=11111_1#11_04088;product=Uncharacterized protein conserved in bacteria,Protein of unknown function (DUF1311);protein_id=gnl|SC|11111_1#11_04088
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 31925 35887 . - 0 ID=11111_1#11_04089;gene=putA;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002243116.1,similar to AA sequence:UniProtKB:P09546,protein motif:CLUSTERS:PRK11809,protein motif:Cdd:COG4230,protein motif:TIGRFAMs:TIGR01238,protein motif:Pfam:PF01619.12;locus_tag=11111_1#11_04089;product=trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase,Bifunctional p [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 36309 37817 . + 0 ID=11111_1#11_04090;gene=putP;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002145994.1,similar to AA sequence:UniProtKB:P07117,protein motif:CLUSTERS:PRK15419,protein motif:Cdd:COG4145,protein motif:TIGRFAMs:TIGR02121,protein motif:Pfam:PF00474.11;locus_tag=11111_1#11_04090;product=sodium/proline symporter,Propionate transporter,proline:sodium symporter PutP,Na+/panthothenate symporter,sodium/p [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 38435 38731 . + 0 ID=11111_1#11_04091;inference=ab initio prediction:Prodigal:2.60;locus_tag=11111_1#11_04091;product=hypothetical protein;protein_id=gnl|SC|11111_1#11_04091
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 38710 39498 . + 0 ID=11111_1#11_04092;gene=phoH;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729855.1,similar to AA sequence:UniProtKB:P0A9K1,protein motif:CLUSTERS:PRK10536,protein motif:Cdd:COG1875,protein motif:Pfam:PF02562.10;locus_tag=11111_1#11_04092;product=phosphate starvation-inducible protein PsiH,Phosphate starvation-inducible protein psiH,hypothetical protein,Predicted ATPase related to phosphate [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 39604 40485 . - 0 ID=11111_1#11_04093;gene=ybbH_2;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_001570898.1,similar to AA sequence:UniProtKB:Q45581,protein motif:CLUSTERS:PRK11337,protein motif:Cdd:COG2222,protein motif:TIGRFAMs:TIGR03127,protein motif:Pfam:PF01418.11;locus_tag=11111_1#11_04093;product=putative transcriptional regulator,Uncharacterized HTH-type transcriptional regulator ybbH,DNA-binding transcrip [...]
+ERS111111|SC|contig000020 Infernal:1.1 ncRNA 40486 40770 . + 0 ID=11111_1#11_04094;inference=COORDINATES:profile:Infernal:1.1;locus_tag=11111_1#11_04094;product=STnc500
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 40771 41673 . - 0 ID=11111_1#11_04095;gene=yidK;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002215057.1,similar to AA sequence:UniProtKB:P31448,protein motif:CLUSTERS:PRK10484,protein motif:Cdd:COG4146,protein motif:TIGRFAMs:TIGR00813,protein motif:Pfam:PF00474.11;locus_tag=11111_1#11_04095;product=sodium-glucose/galactose cotransporter,Uncharacterized symporter yidK,putative transporter,Predicted symporter,tra [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 41741 42268 . - 0 ID=11111_1#11_04096;gene=sglT;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002215057.1,similar to AA sequence:UniProtKB:P96169,protein motif:CLUSTERS:PRK10484,protein motif:Cdd:COG4146,protein motif:TIGRFAMs:TIGR00813,protein motif:Pfam:PF00474.11;locus_tag=11111_1#11_04096;product=sodium-glucose/galactose cotransporter,Na(+)/glucose symporter,putative transporter,Predicted symporter,transporte [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 42605 43285 . - 0 ID=11111_1#11_04097;eC_number=5.1.3.9;gene=nanE;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_001570896.2,similar to AA sequence:UniProtKB:P60668,protein motif:CLUSTERS:PRK01130,protein motif:Pfam:PF04131.8;locus_tag=11111_1#11_04097;product=N-acetylmannosamine-6-phosphate 2-epimerase,Putative N-acetylmannosamine-6-phosphate 2-epimerase,N-acetylmannosamine-6-phosphate 2-epimerase,Putative N-acet [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 43804 44946 . + 0 ID=11111_1#11_04098;eC_number=5.1.3.24;gene=nanM;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_001570895.1,similar to AA sequence:UniProtKB:P44544,protein motif:CLUSTERS:PRK14131,protein motif:TIGRFAMs:TIGR03547,protein motif:Pfam:PF01344.19;locus_tag=11111_1#11_04098;product=N-acetylneuraminic acid mutarotase,N-acetylneuraminate epimerase precursor,N-acetylneuraminic acid mutarotase,mutatrotase [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 44992 45684 . + 0 ID=11111_1#11_04099;gene=yiiy;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_216068.1,similar to AA sequence:UniProtKB:Q934G3,protein motif:CLUSTERS:PRK09980,protein motif:Cdd:COG3203,protein motif:Pfam:PF06178.7;locus_tag=11111_1#11_04099;product=outer membrane protein,Oligogalacturonate-specific porin kdgM precursor,outer membrane porin L,Outer membrane protein (porin),Oligogalacturonate-specif [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 45967 47247 . + 0 ID=11111_1#11_04100;gene=nanT_3;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_001570893.1,similar to AA sequence:UniProtKB:P41036,protein motif:CLUSTERS:PRK12307,protein motif:Cdd:COG2814,protein motif:TIGRFAMs:TIGR00891,protein motif:Pfam:PF00083.18;locus_tag=11111_1#11_04100;product=putative sialic acid transporter,Sialic acid permease,putative sialic acid transporter,Arabinose efflux permease [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 47261 48364 . + 0 ID=11111_1#11_04101;eC_number=1.1.1.292;gene=yjhC;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_216069.1,similar to AA sequence:UniProtKB:Q2I8V6,protein motif:CLUSTERS:PRK11579,protein motif:Pfam:PF01408.16;locus_tag=11111_1#11_04101;product=dehydrogenase-like protein,1%2C5-anhydro-D-fructose reductase,putative oxidoreductase,Oxidoreductase family%2C NAD-binding Rossmann fold;protein_id=gnl|SC|1 [...]
+ERS111111|SC|contig000020 Aragorn:1.2.36 tRNA 48701 48788 . - 0 ID=11111_1#11_04102;inference=COORDINATES:profile:Aragorn:1.2.36;locus_tag=11111_1#11_04102;product=tRNA-Ser(gga)
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 49024 49962 . + 0 ID=11111_1#11_04103;eC_number=1.1.1.79;gene=ghrA;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729856.1,similar to AA sequence:UniProtKB:Q8ZQ30,protein motif:CLUSTERS:PRK15469,protein motif:Cdd:COG1932,protein motif:TIGRFAMs:TIGR01327,protein motif:Pfam:PF02826.13;locus_tag=11111_1#11_04103;product=2-hydroxyacid dehydrogenase,Glyoxylate/hydroxypyruvate reductase A,bifunctional glyoxylate/hydr [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 50047 50784 . + 0 ID=11111_1#11_04104;eC_number=3.1.3.-;gene=ycdX;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_001570887.1,similar to AA sequence:UniProtKB:P75914,protein motif:CLUSTERS:PRK09248,protein motif:Cdd:COG1387,protein motif:TIGRFAMs:TIGR01856,protein motif:Pfam:PF02811.13;locus_tag=11111_1#11_04104;product=putative hydrolase,Probable phosphatase YcdX,putative hydrolase,Histidinol phosphatase and relat [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 50808 51362 . + 0 ID=11111_1#11_04105;gene=ycdY;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002146908.1,similar to AA sequence:UniProtKB:P75915,protein motif:CLUSTERS:PRK11621,protein motif:Cdd:COG3381,protein motif:Pfam:PF02613.9;locus_tag=11111_1#11_04105;product=chaperone%2C TorD family,Chaperone protein YcdY,twin-argninine leader-binding protein DmsD,Uncharacterized component of anaerobic dehydrogenases,Nit [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 51451 51945 . + 0 ID=11111_1#11_04106;gene=ycdZ;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P75916,protein motif:Pfam:PF06496.5;locus_tag=11111_1#11_04106;product=Inner membrane protein ycdZ,Protein of unknown function (DUF1097);protein_id=gnl|SC|11111_1#11_04106
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 51983 52816 . - 0 ID=11111_1#11_04107;gene=csgG;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729860.1,protein motif:CLUSTERS:PRK15184,protein motif:Pfam:PF03783.8;locus_tag=11111_1#11_04107;product=assembly/transport component in curli production,curli production assembly/transport protein CsgG,Curli production assembly/transport component CsgG;protein_id=gnl|SC|11111_1#11_04107
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 52843 53259 . - 0 ID=11111_1#11_04108;gene=csgF;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729861.1,protein motif:CLUSTERS:PRK10050,protein motif:Pfam:PF10614.3;locus_tag=11111_1#11_04108;product=assembly/transport component in curli production,curli assembly protein CsgF,Curli production assembly/transport component CsgF;protein_id=gnl|SC|11111_1#11_04108
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 53286 53681 . - 0 ID=11111_1#11_04109;gene=csgE;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729862.1,protein motif:CLUSTERS:PRK10386,protein motif:Pfam:PF10627.3;locus_tag=11111_1#11_04109;product=assembly/transport component in curli production,curli assembly protein CsgE,Curli assembly protein CsgE;protein_id=gnl|SC|11111_1#11_04109
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 53710 54336 . - 0 ID=11111_1#11_04110;gene=csgD;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729863.1,similar to AA sequence:UniProtKB:P52106,protein motif:CLUSTERS:PRK10100,protein motif:Cdd:COG2909,protein motif:TIGRFAMs:TIGR03020,protein motif:Pfam:PF00196.13;locus_tag=11111_1#11_04110;product=regulatory protein,CsgBAC operon transcriptional regulatory protein,DNA-binding transcriptional regulator CsgD,ATP [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 55092 55547 . + 0 ID=11111_1#11_04111;gene=csgB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729864.1,similar to AA sequence:UniProtKB:P0A1E9,protein motif:CLUSTERS:PRK10101,protein motif:Pfam:PF07012.6;locus_tag=11111_1#11_04111;product=nucleation component of curlin monomers,Fimbrin SEF17 minor subunit,curlin minor subunit CsgB,Curlin associated repeat;protein_id=gnl|SC|11111_1#11_04111
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 55589 56044 . + 0 ID=11111_1#11_04112;gene=csgA;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729865.1,similar to AA sequence:UniProtKB:P0A1E7,protein motif:CLUSTERS:PRK10051,protein motif:Pfam:PF07012.6;locus_tag=11111_1#11_04112;product=major curlin subunit,Fimbrin SEF17,major curlin subunit,Curlin associated repeat;protein_id=gnl|SC|11111_1#11_04112
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 56106 56432 . + 0 ID=11111_1#11_04113;gene=csgC;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_007470940.1,similar to AA sequence:UniProtKB:P0A1Z9,protein motif:CLUSTERS:PRK10102,protein motif:Pfam:PF10610.3;locus_tag=11111_1#11_04113;product=curli assembly protein CsgC,Curli assembly protein CsgC precursor,curli assembly protein CsgC,Thin aggregative fimbriae synthesis protein;protein_id=gnl|SC|11111_1#11_04113
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 56564 56884 . + 0 ID=11111_1#11_04114;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_006087410.1;locus_tag=11111_1#11_04114;product=Fimbrial protein;protein_id=gnl|SC|11111_1#11_04114
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 56972 57511 . + 0 ID=11111_1#11_04115;eC_number=3.5.1.-;gene=ymdB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_006087411.1,similar to AA sequence:UniProtKB:P0A8D6,protein motif:CLUSTERS:PRK00431,protein motif:Pfam:PF01661.15;locus_tag=11111_1#11_04115;product=Macro domain%2C possibly ADP-ribose binding module,O-acetyl-ADP-ribose deacetylase,RNase III inhibitor,Macro domain;protein_id=gnl|SC|11111_1#11_04115
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 57450 58934 . + 0 ID=11111_1#11_04116;eC_number=2.7.8.-;gene=ybhO_2;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_001570877.2,similar to AA sequence:UniProtKB:P0AA84,protein motif:CLUSTERS:PRK01642,protein motif:TIGRFAMs:TIGR04265;locus_tag=11111_1#11_04116;product=phospholipase,Putative cardiolipin synthase YbhO,cardiolipin synthetase,cardiolipin synthase;protein_id=gnl|SC|11111_1#11_04116
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 58951 60105 . - 0 ID=11111_1#11_04117;eC_number=2.1.-.-;gene=mdoC;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_001570876.1,similar to AA sequence:UniProtKB:P75920,protein motif:CLUSTERS:PRK03854,protein motif:Cdd:COG3274,protein motif:Pfam:PF01757.16;locus_tag=11111_1#11_04117;product=glucans biosynthesis protein,Glucans biosynthesis protein C,glucans biosynthesis protein,Uncharacterized protein conserved in bac [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 60359 61912 . + 0 ID=11111_1#11_04118;gene=mdoG;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_001570875.1,similar to AA sequence:UniProtKB:P33136,protein motif:CLUSTERS:PRK13274,protein motif:Cdd:COG3131,protein motif:Pfam:PF04349.6;locus_tag=11111_1#11_04118;product=glucan biosynthesis protein G,Glucans biosynthesis protein G precursor,glucan biosynthesis protein G,Periplasmic glucans biosynthesis protein,Peripl [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 61905 64448 . + 0 ID=11111_1#11_04119;eC_number=2.4.1.-;gene=mdoH;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_216085.1,similar to AA sequence:UniProtKB:P62517,protein motif:CLUSTERS:PRK05454,protein motif:Pfam:PF00535.20;locus_tag=11111_1#11_04119;product=glucosyltransferase MdoH,Glucans biosynthesis glucosyltransferase H,glucosyltransferase MdoH,Glycosyl transferase family 2;protein_id=gnl|SC|11111_1#11_04119
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 64522 64749 . + 0 ID=11111_1#11_04120;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729872.1,protein motif:CLUSTERS:PRK10175,protein motif:Cdd:COG5645,protein motif:Pfam:PF07119.6;locus_tag=11111_1#11_04120;product=lipoprotein,lipoprotein,Predicted periplasmic lipoprotein,Protein of unknown function (DUF1375);protein_id=gnl|SC|11111_1#11_04120
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 64750 65124 . - 0 ID=11111_1#11_04121;gene=msyB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729873.1,protein motif:CLUSTERS:PRK11467;locus_tag=11111_1#11_04121;product=acidic protein MsyB,secY/secA suppressor protein;protein_id=gnl|SC|11111_1#11_04121
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 65206 66420 . - 0 ID=11111_1#11_04122;gene=yceE;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729874.1,similar to AA sequence:UniProtKB:O31762,protein motif:CLUSTERS:PRK09874,protein motif:Cdd:COG2814,protein motif:TIGRFAMs:TIGR00880,protein motif:Pfam:PF07690.10;locus_tag=11111_1#11_04122;product=membrane transport protein,Bacillibactin exporter,drug efflux system protein MdtG,Arabinose efflux permease,multid [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 66575 67495 . - 0 ID=11111_1#11_04123;eC_number=2.3.1.-;gene=htrB_2;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729875.1,similar to AA sequence:UniProtKB:P0ACV0,protein motif:CLUSTERS:PRK06860,protein motif:Cdd:COG1560,protein motif:TIGRFAMs:TIGR02207,protein motif:Pfam:PF03279.7;locus_tag=11111_1#11_04123;product=lipid A biosynthesis lauroyl acyltransferase,Lipid A biosynthesis lauroyl acyltransferase,lipid [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 67715 68767 . + 0 ID=11111_1#11_04124;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_006087420.1,protein motif:CLUSTERS:PRK00142,protein motif:Cdd:COG2210,protein motif:Pfam:PF00581.14;locus_tag=11111_1#11_04124;product=Rhodanese-like sulfurtransferase,putative rhodanese-related sulfurtransferase,Uncharacterized conserved protein,Rhodanese-like domain;protein_id=gnl|SC|11111_1#11_04124
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 68819 69394 . - 0 ID=11111_1#11_04125;gene=yceI_2;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_006087865.1,similar to AA sequence:UniProtKB:P0A8X2,protein motif:CLUSTERS:PRK03757,protein motif:Cdd:COG2353,protein motif:Pfam:PF04264.7;locus_tag=11111_1#11_04125;product=YceI protein,hypothetical protein,hypothetical protein,Uncharacterized conserved protein,YceI-like domain;protein_id=gnl|SC|11111_1#11_04125
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 69391 69795 . - 0 ID=11111_1#11_04126;gene=yceJ;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_005212184.1,similar to AA sequence:UniProtKB:P75925,protein motif:CLUSTERS:PRK11513,protein motif:Pfam:PF00033.13;locus_tag=11111_1#11_04126;product=cytochrome b561-like protein 2,Cytochrome b561 homolog 2,cytochrome b561,Cytochrome b(N-terminal)/b6/petB;protein_id=gnl|SC|11111_1#11_04126
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 70226 70339 . - 0 ID=11111_1#11_04127;gene=yceO;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_216094.1,similar to AA sequence:UniProtKB:P64442,protein motif:Pfam:PF10968.2;locus_tag=11111_1#11_04127;product=inner membrane protein,hypothetical protein,Protein of unknown function (DUF2770);protein_id=gnl|SC|11111_1#11_04127
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 70380 71498 . - 0 ID=11111_1#11_04128;eC_number=1.5.3.1,1.5.3.-;gene=solA;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729880.1,similar to AA sequence:UniProtKB:P40874,protein motif:CLUSTERS:PRK11259,protein motif:Cdd:COG4121,protein motif:TIGRFAMs:TIGR01377,protein motif:Pfam:PF01266.18;locus_tag=11111_1#11_04128;product=sarcosine oxidase,N-methyl-L-tryptophan oxidase,N-methyltryptophan oxidase,Uncharacteriz [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 71611 71865 . - 0 ID=11111_1#11_04129;gene=bssS;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_001570863.1,protein motif:CLUSTERS:PRK12301;locus_tag=11111_1#11_04129;product=biofilm formation regulatory protein BssS,biofilm formation regulatory protein BssS;protein_id=gnl|SC|11111_1#11_04129
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 72155 72418 . - 0 ID=11111_1#11_04130;gene=dinI_3;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729882.1,similar to AA sequence:UniProtKB:P0ABR1,protein motif:CLUSTERS:PRK10597,protein motif:Pfam:PF06183.7;locus_tag=11111_1#11_04130;product=damage-inducible protein,DNA-damage-inducible protein I,DNA damage-inducible protein I,DinI-like family;protein_id=gnl|SC|11111_1#11_04130
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 72492 73538 . - 0 ID=11111_1#11_04131;eC_number=3.5.2.3,3.5.2.3;gene=pyrC;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729883.1,similar to AA sequence:UniProtKB:P06204,protein motif:CLUSTERS:PRK05451,protein motif:Cdd:COG0418,protein motif:TIGRFAMs:TIGR00856,protein motif:Pfam:PF01979.14;locus_tag=11111_1#11_04131;product=dihydroorotase,Dihydroorotase,dihydroorotase,Dihydroorotase,dihydroorotase%2C homodimeri [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 73642 74268 . - 0 ID=11111_1#11_04132;gene=yceB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_007470922.1,similar to AA sequence:UniProtKB:P0AB26,protein motif:CLUSTERS:PRK10598,protein motif:Pfam:PF07273.6;locus_tag=11111_1#11_04132;product=lipoprotein,Uncharacterized lipoprotein yceB precursor,lipoprotein,Protein of unknown function (DUF1439);protein_id=gnl|SC|11111_1#11_04132
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 74326 74973 . - 0 ID=11111_1#11_04133;gene=grxB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729885.1,similar to AA sequence:UniProtKB:P0AC59,protein motif:CLUSTERS:PRK10387,protein motif:TIGRFAMs:TIGR02182,protein motif:Pfam:PF04399.7;locus_tag=11111_1#11_04133;product=glutaredoxin,Glutaredoxin-2,glutaredoxin 2,glutaredoxin%2C GrxB family,Glutaredoxin 2%2C C terminal domain;protein_id=gnl|SC|11111_1#11_04133
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 75037 76245 . - 0 ID=11111_1#11_04134;gene=mdtH;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_001570858.1,similar to AA sequence:UniProtKB:P69367,protein motif:CLUSTERS:PRK11646,protein motif:Cdd:COG2814,protein motif:TIGRFAMs:TIGR00880,protein motif:Pfam:PF07690.10;locus_tag=11111_1#11_04134;product=multidrug resistance protein MdtH,Multidrug resistance protein MdtH,multidrug resistance protein MdtH,Arabinose ef [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 76482 77066 . + 0 ID=11111_1#11_04135;eC_number=2.3.1.-;gene=rimJ;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729887.1,similar to AA sequence:UniProtKB:P96579,protein motif:CLUSTERS:PRK10809,protein motif:TIGRFAMs:TIGR03585,protein motif:Pfam:PF00583.18;locus_tag=11111_1#11_04135;product=ribosomal-protein-alanine acetyltransferase,Putative ribosomal N-acetyltransferase YdaF,ribosomal-protein-S5-alanine N-ace [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 77102 77749 . + 0 ID=11111_1#11_04136;gene=yceH;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P29217,protein motif:CLUSTERS:PRK11239,protein motif:Cdd:COG3132,protein motif:Pfam:PF04337.6;locus_tag=11111_1#11_04136;product=G20.3,hypothetical protein,Uncharacterized protein conserved in bacteria,Protein of unknown function%2C DUF480;protein_id=gnl|SC|11111_1#11_04136
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 77751 78674 . + 0 ID=11111_1#11_04137;gene=mviM;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729889.1,similar to AA sequence:UniProtKB:P75931,protein motif:CLUSTERS:PRK11579,protein motif:Cdd:COG3132,protein motif:Pfam:PF01408.16;locus_tag=11111_1#11_04137;product=virulence factor MviM,Virulence factor mviM homolog,putative oxidoreductase,Uncharacterized protein conserved in bacteria,Oxidoreductase family%2C [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 78939 80513 . + 0 ID=11111_1#11_04138;gene=mviN;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002146873.1,similar to AA sequence:UniProtKB:P37169,protein motif:TIGRFAMs:TIGR01695,protein motif:Pfam:PF03023.8;locus_tag=11111_1#11_04138;product=integral membrane protein MviN,hypothetical protein,integral membrane protein MviN,MviN-like protein;protein_id=gnl|SC|11111_1#11_04138
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 80595 81017 . - 0 ID=11111_1#11_04139;gene=flgN;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729891.1,protein motif:CLUSTERS:PRK15459,protein motif:Pfam:PF05130.6;locus_tag=11111_1#11_04139;product=flagella synthesis protein FlgN,flagella synthesis chaperone protein FlgN,FlgN protein;protein_id=gnl|SC|11111_1#11_04139
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 81022 81315 . - 0 ID=11111_1#11_04140;gene=flgM;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729892.1,similar to AA sequence:UniProtKB:P26477,protein motif:CLUSTERS:PRK10810,protein motif:TIGRFAMs:TIGR03824,protein motif:Pfam:PF04316.7;locus_tag=11111_1#11_04140;product=negative regulator of flagellin synthesis (anti-sigma factor),Anti-sigma-28 factor,anti-sigma28 factor FlgM,flagellar biosynthesis anti-sigma [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 81407 82066 . - 0 ID=11111_1#11_04141;gene=flgA;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729893.1,protein motif:CLUSTERS:PRK07018,protein motif:TIGRFAMs:TIGR03170,protein motif:Pfam:PF08666.6;locus_tag=11111_1#11_04141;product=flagellar basal body P-ring protein FlgA,flagellar basal body P-ring biosynthesis protein FlgA,flagella basal body P-ring formation protein FlgA,SAF domain;protein_id=gnl|SC|11111_1 [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 82223 82639 . + 0 ID=11111_1#11_04142;gene=flgB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729894.1,similar to AA sequence:UniProtKB:P16437,protein motif:CLUSTERS:PRK05680,protein motif:Cdd:COG1815,protein motif:TIGRFAMs:TIGR01396,protein motif:Pfam:PF00460.14;locus_tag=11111_1#11_04142;product=flagellar basal-body rod protein FlgB,Putative proximal rod protein,flagellar basal body rod protein FlgB,Flagella [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 82643 83047 . + 0 ID=11111_1#11_04143;gene=flgC;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729895.1,similar to AA sequence:UniProtKB:P0A1I7,protein motif:CLUSTERS:PRK05681,protein motif:Cdd:COG4786,protein motif:TIGRFAMs:TIGR01395,protein motif:Pfam:PF06429.7;locus_tag=11111_1#11_04143;product=flagellar basal-body rod protein FlgC,Putative proximal rod protein,flagellar basal body rod protein FlgC,Flagellar [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 83059 83757 . + 0 ID=11111_1#11_04144;gene=flgD;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729896.1,similar to AA sequence:UniProtKB:P0A1I9,protein motif:CLUSTERS:PRK06655,protein motif:Cdd:COG1843,protein motif:Pfam:PF03963.8;locus_tag=11111_1#11_04144;product=flagellar hook formation protein FlgD,Basal-body rod modification protein flgD,flagellar basal body rod modification protein,Flagellar hook capping [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 83784 84995 . + 0 ID=11111_1#11_04145;gene=flgE;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002146866.1,similar to AA sequence:UniProtKB:P0A1J1,protein motif:CLUSTERS:PRK05682,protein motif:Cdd:COG1749,protein motif:TIGRFAMs:TIGR03506,protein motif:Pfam:PF07559.8;locus_tag=11111_1#11_04145;product=flagellar hook protein FlgE,Flagellar hook protein flgE,flagellar hook protein FlgE,Flagellar hook protein FlgE,fla [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 85016 85771 . + 0 ID=11111_1#11_04146;gene=flgF;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729898.1,similar to AA sequence:UniProtKB:P16323,protein motif:CLUSTERS:PRK12640,protein motif:Cdd:COG4787,protein motif:TIGRFAMs:TIGR03506,protein motif:Pfam:PF06429.7;locus_tag=11111_1#11_04146;product=flagellar basal-body rod protein FlgF,Putative proximal rod protein,flagellar basal body rod protein FlgF,Flagellar [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 85785 86567 . + 0 ID=11111_1#11_04147;gene=flgG;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729899.1,similar to AA sequence:UniProtKB:P0A1J3,protein motif:CLUSTERS:PRK12694,protein motif:Cdd:COG4786,protein motif:TIGRFAMs:TIGR02488,protein motif:Pfam:PF06429.7;locus_tag=11111_1#11_04147;product=flagellar basal-body rod protein FlgG (distal rod protein),Distal rod protein,flagellar basal body rod protein FlgG [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 86655 87320 . + 0 ID=11111_1#11_04148;gene=flgH;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729900.1,similar to AA sequence:UniProtKB:Q9PPM0,protein motif:CLUSTERS:PRK00249,protein motif:Pfam:PF02107.10;locus_tag=11111_1#11_04148;product=flagellar L-ring protein,Basal body L-ring protein,flagellar basal body L-ring protein,Flagellar L-ring protein;protein_id=gnl|SC|11111_1#11_04148
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 87332 88429 . + 0 ID=11111_1#11_04149;gene=flgI;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729901.1,similar to AA sequence:UniProtKB:Q9PMJ8,protein motif:CLUSTERS:PRK05303,protein motif:Cdd:COG1706,protein motif:Pfam:PF02119.10;locus_tag=11111_1#11_04149;product=flagellar P-ring protein,Basal body P-ring protein,flagellar basal body P-ring protein,Flagellar basal-body P-ring protein,Flagellar P-ring protein [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 88429 89379 . + 0 ID=11111_1#11_04150;eC_number=3.2.1.-;gene=flgJ;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729902.1,similar to AA sequence:UniProtKB:P15931,protein motif:CLUSTERS:PRK05684,protein motif:Cdd:COG3951,protein motif:TIGRFAMs:TIGR02541,protein motif:Pfam:PF01832.14;locus_tag=11111_1#11_04150;product=flagellar protein FlgJ,Peptidoglycan hydrolase flgJ,flagellar rod assembly protein/muramidase Fl [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 89444 91105 . + 0 ID=11111_1#11_04151;gene=flgK;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729903.1,similar to AA sequence:UniProtKB:P0A1J5,protein motif:CLUSTERS:PRK08147,protein motif:Cdd:COG1749,protein motif:TIGRFAMs:TIGR02492,protein motif:Pfam:PF06429.7;locus_tag=11111_1#11_04151;product=flagellar hook-associated protein 1,Flagellar hook-associated protein 1,flagellar hook-associated protein FlgK,Flag [...]
+ERS111111|SC|contig000020 Prodigal:2.60 CDS 91120 92073 . + 0 ID=11111_1#11_04152;gene=flgL;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729904.1,similar to AA sequence:UniProtKB:P16326,protein motif:CLUSTERS:PRK08027,protein motif:Cdd:COG3951,protein motif:TIGRFAMs:TIGR02550,protein motif:Pfam:PF00669.14;locus_tag=11111_1#11_04152;product=flagellar hook-associated protein 3,Hook-filament junction protein,flagellar hook-associated protein FlgL,Rod bind [...]
+ERS111111|SC|contig000020 Infernal:1.1 ncRNA 92162 92255 . + 0 ID=11111_1#11_04153;inference=COORDINATES:profile:Infernal:1.1;locus_tag=11111_1#11_04153;product=STnc490k
+##FASTA
+>ERS111111|SC|contig000020
+TATCCGGGCAGCCCGTTTACGGGCCGTAAGTAACGAAGTTTGATGCAAATGTCAGATCGT
+ATGCGCCTGTTAGGGCGCGGCTGGTAAGAGAGCCTTACAGGCGCATCAGAAAAACCTCCG
+GCTATGCCGGAGGATATTTATTTTTTGGGCGCTTAGAATATAGTTAGAAAATACTGCTAG
+AACATTTCCCGAAAAAACGGACTACGTGGGTTTTTAGTTTCTTTTCGTTTCTTGATGTGT
+CTATTTATTGAAGATGTAGACCATTCTGGGAGGTGAAGGATGCCCCATCTCTTTCAGAAT
+AATGTTGGTATATTCGACAACAGGGCCTCTTGGATGATTTTCTTCTTTATCCTGAAGATG
+GGTCAGTGCATGTACAACTTCATGAGTAAATGAACGTTTTGTGTCAAAAAGTTGTCTTCC
+TTCGTTACTTTCATAATGTTCGGTATATGAATCATCAGAATCGTCCAGATTGAGACAAAT
+AACTTTCCTGCCTTCTGAAAGTTTGAAGTGTTCCTGAGCCACGGTAGTTTCAAAGGCTTC
+GCCTGCCCCCGGTAGCCAGCGCTGCTCCACATCATGTAGTTCTTTTTCATATGCGTAATT
+CATCAGTCTGCGGAATGTTTCGCTTTGGGTATACGCATTTTGAAGTACGGAGGATAGTTC
+ATCGTAGCATTCGTCATAAGTGTCGTCATCAATTTCTGTATCAGGGTCTATTCCACCCGC
+GCCTGAGATAAGGTACTCCACCACACACTCTGGCTCCAGACGGAATTCACTGTTTATGGC
+AAGGCTGTCATGAGCAAGGCGTAGCCGTGAGGGGTTTGGTGCATGTTCGGGAATATCGGG
+GAAAACAGGTGTATCTGCGGTATTTAATCCATATGTGGATACTCCGCTTTGAGGTATTAA
+TCTGTAGGTGACCGGAAGCATAATTTCTTATTCCCTGACTGCAATTATGAATTATTTAAA
+TTAAACAATAATAGTGTTTTTAGTTAATGTGCCACATACAGATAACGCTATGATTCAGGC
+AAAACCAACAAGTAATACGCTGAAAATGTTATTTATAATGAAGCTTAGGGGCGGGGTTTG
+TTTAATAAAACAAGGAGGGCTTCTGTTTGAATACTTCTTGTTTATAAAATCCCTTTATCT
+CGACTAAAATATTGGATGGGGGAAAAGCGTTTTATCATTGTAATCCGGGAGTGGAGTAGG
+GGTATGTTGACTACCTGTCAGATCGGCTCCTGTTAATGCTTTCGCTAAAGTTAGAGCTAT
+CTTATCTAATTTTGCACCATTTAGTTTGGTGTCAGTTAAGTCTGAGCCGAATAGAATTGC
+AGCGGTTAAGTTTACACCGGACATGTTAGCGCAAGTCAGGTCTGCGTGAGTCAGGTTTGC
+TTTAGTCATGTTTGAACCCATTAGATTTACAGCGTGTAGATTTGCACAACACAAATTTGC
+ACCGACTAAATTTACATTAGATAGATTTGTTTCACGGAAATCTGCATTAGAAGCATCTAT
+GTCTGACAAATCTTCTCCCTGGAAATCTTTATGAGCTAGGTTTACTCCGCGCAGGTTCAG
+AAAACCATCCTCGGTTATAAGTGAATCAGGCTGTTGTATATTATGTTTACTCATCAGTTT
+TAACATTCGACATACATTCCAAAATCTCTCACTATCAACTTTATCCGTTACAGTTTTTCC
+ATTTTTGTTCACTTCAATAGTGACCATGGGATCCGTATTTTCGGATGCTGCTCCACATGA
+CAGACATATAGTACACCCGTTGACATCCTCCAGAAATATTTTATTACCATCGAAGAAAGC
+ATCTTTATTTACATATAATAATGATGTGGTCAGTTTTCCAATTACCTCCCAAAAGCATCT
+TTCATTGCTTCTTCTTACTCCACCACAGGTAAAAAAATTGACAAACCATTCCAGTATACC
+GCGTGGTGAAGTTGCACTTTTCATTGCTTCTTTCGTACCGGTACCGGCCGCATGCAAATA
+TCTTAATATATTTTCTGGGGACGCGTTAGTTATTGGCATTTTGATTCCTTCTTATGGAAG
+TGAGTCGATTCCTTATAGGTGTGAGTCAAGTCACATTTATACAAGGAATAATAAAAAAAG
+ATATAAGGTGATTTTTGTATTTAGAGCTTTGGTTGAGTATGAGTAGGTGTCTGGCATCTG
+ACAAGAGGCGATGATATCTGCCATAACGGTGAAGCAGAAGTAATATCACCCGTGAATAAT
+AAGATTATCCTTGCTATTGACTTCCTTCATTTCCAGCATAGCTTACGCCTCATCATCATT
+GAATAAACAATTAAGTTTGTTGAGCGAAAATTTACTTAAAGAAAAAATAATAAGCTTTAA
+TATTTTTTGCAGCATTTCAACTTATAGCAGAATAAATGTGCGTAGATGGCGTAAAAACCT
+GATGAGCAGGAATACTTACACACTAAAAATGCTCCCGCAAACAGAGCAAAATGAGAAAGA
+GGAACGTTTGCCCTTTACATTTCCACCAAAGATTCTGGTTTTGTCTCTTGTAAAGGGCAT
+ACGTATCGCGTTTTATCTCATTAAGAAAGTATGTTGACGTATTAAATTATGCATAATGCT
+CTTTCAATTGCTTCACGTTTGAAATGAATAATTCAAAACCAGTGAGCGCCTCTTCTTCGG
+TACTGGTTTGCGGCAAGCGATAAAGCGCCACTAAAGCAGTATTGTCTGCATCAGCGCCGA
+TAGTGACGGCGCTGGCGTAGTTAAGACGTAAAAAATGCTGCAAAGTCAGAGTGTCGTCAG
+GCAGTGGCATAAAGGGACAGCACATTTCCAGTGTATGATCGGATTCATTAAAATAAACCT
+GTATCCCATCATCAATGATAAGCAGTGGCTCATCTTCTGGCGCATCCAGGCCTAACGCGT
+CATATAAACGATTTAATAGACTTTCCATATAGTTACCTCAAGACTCAAGATGTGATTAAT
+GAAGAAATACCTTTTACTGACTGCCAAATATTTTCATCCCCAACTCGTTTTTGATAGGAA
+AGATTGAGCACCTCTGGCGATAAATTTTTCATTACTTTGTTTCCCGCCCCGCCCGTATTT
+TGTTTCTGAATCTCCAGGTTACCGCTATTCAGTAATACTTTTTGGAAAATTTTCTGTCCA
+CCGCTATCCGGAAGACTACCAGGCGCACTTAACATATGGGTCTGATGGAAAGAAATGAGC
+TCTCGCTTGATTTCTGAATCCATCATCCCTGTACGATCTTTGCCGCTTTTACAATTCCAG
+GCGGGCACCGCGTCAATTTCATGGGCTAACATGGCAAGGCGTTGTGCGAGTTTATAGGGT
+TCGCCGCCATCTTTATGATGTTGGTTATTTTTCCAGATATCCTTAATCTGGCGCGCTAAT
+GTATTGACGACCTCATAATTATCCGGGTATTGCGCCAGCCATTCGCCAACCCAGCCACCT
+GGTCTGGCTTCAGGGCGTAAATCATTGCCTAATAACTGATGTAGCGCTTCGGCATTATAG
+CTATCTGATGCTTTAAGGCCAAAGCCGAGCTTGAGCGCCAGCTCATTAACACCCACATTA
+AATGCGGCGACGTCCGGTTTTATTTTTACCGTCTGTAGATCGCCATCTTTATTGCGGATT
+TTTAAATGAATCATTTTTCCCGGCTGGGTCAACGATTGCCATGCGCGCATTTGATCCTCG
+ACCATAGTTCCCTCTTTGCCGAAAATATTCGACGCGGTGAGTAACCCGACGGATACCAGT
+TTCAGGCTTACCGCTTCGCCCTCTAAGGCTCTGTTAAGCAACTCAGGTTTACTAAAAAGT
+GCCGCAGCTAATACTTCTTTGGCTTTGTTTTCAGCGCCGGCCTGACGCAGAAGCGGATCT
+TTTTCATGATAGGGGGAAAGCACACCATGACGTATCCCGCAAAAAAGCGTTTTATCTTTA
+CCGTCCTCATGCACACTCACCGTGGACATCCACAAATTATTGGCGTGATGAATATTCTTG
+GTATCCCAACTGCATACGCCCTTTCCCTCATAAGCACTGGGAAAGATATCTTTTGCGCCG
+ATTTTCATCTCTGCGGCAGGGAGCTGCGTGTTGGTATAGTGATGCCCGTTATGCGTGAGT
+GTATTTTTTATGGTTTGCCAGGGCTGGTTATTGAGCTGCTTGACCTGAGCATCTCTAAAC
+GCTACTGCCGCAAAGCGATGAGCTTCTTTTGCAGGTAAGCCATTTTGCTGCTGAGTGCGT
+GCTGCAATAAGTTCGATAAGATTTTTCTTCAATGCTTTTGCCGCAGCTTCTTCTTGTTTT
+GTTGCTGGCCGGTCCGCTTTAACTTTGGCTAACTCCATTTGGTTTGCCATTGACGTTAGA
+ACCGGGTCTTGTTTACCCAGAACGGTTGCCGCGACGGTAAGAAGATCGCGCTGTAAGTTA
+TAGAGGTTATGCAGCGAGTGGTTAGACGTCTTCTGATGCTGTAGATAATTCCCCCATGTC
+GCGCCAGGTTCTCGCAGGACAATAATTTCCGGGCGAGCGTCGGGCGCTTTAGCCGGCGCT
+TTGCCCTGGCCTGAGAGAATCTGCATTCCGTTGTATAAGGTTTTTTGTAGGCTTTTAAAA
+GCCTCCTGGGTTTTTAGTGAAGCTGAGTGATAGAAGCTCTGTATTTGCATAGCGTTTTTA
+ATATTCCTGAATAGGGGAGTGGGAACATTCAACAGGGTTAACAATCTTTTAAAAGGATGT
+GACTTTTATGCACCAGGAACTTTAAAAAAATGTCCTTTTTAATGAGGAAACGCTTCTGAT
+CAGGCGGGGAGGCATCCTGACGTCCATACGTAGTGGCGATCATGGGGGAGATCGGTACAT
+CAAATGTTCATAAAATCTACAAACTTCACAATTTAGGGCACAACTTTTATTGAAAACCCA
+CCTTCTTGATTCAGATCAAATTCACCGATTTACTCCTGCGTAAAGTAACGGCGTTACATC
+AAATGTTATACAGGTGTGTGTATGCCAGCAAAGCCCCGGACGAGTAAGACCGTGACGAAG
+AATATTCGTTTTTCCTATTCCATGCTTGAACAGATAGAATTCGCGTTGAAATCTGAAAAG
+ACGCGGAATTTTTCAGCATGGGTAAAAGAGGCCTGTCGGGAAAAGTTATGTAACACGGGA
+CATAAGCTGTAGTTATCGTCTTATGTAAGAGGGGGCGGCCATTTTGAAAAGAACAACGTG
+CTTATATACCTCCTGGGTCTTTGCCGCTTTTGTCTCTCTGCTGATATTTGTCTGGAGTGT
+CATAAACTATCCTCTCTATGAATCCATAATAATTATTGTCTTTTATATCTGGCTAATTCT
+GGTACCGCTTTATCTTATTGTGTATGAGTGGCTAATAGATTGTCATTAAATTTATGGCTG
+CGTACTTGAAAAGTGATATTTCATATCTGTGCGGTAAGTCATTGTCGTAATAATATTATT
+GGTCAGGCGACGGGCGAGCGTCTGCGCATTTTGCATCGTTTTATCTTCAAAATTTTGCAG
+TAAGCGTTGTGCTTCTTTCGGATGCGACGCATATAATCTCAGATAGCTCTGCTCCATCTT
+ATACTGTTGCTTAGCTGTTTGCTGTTCAAATGTTTTCCAGGCATGTTGCACATCTGGCGC
+AAACGTATTGTAGTCTTGCATAACCAGTGTTTGCAGCGTGCGGAATGTCCAGTAGGTAGA
+GTCGTTGCTCGCCCGATCGGTTCCTTTATCATCTCCGGGTTGATAATGACGCATCCCCTG
+GTAATAGGGGAGATAGACGCTAAGAGATGGCATTCCATAGGCGATGTATTCTACGTTGCC
+GATAGCCTGCGGTAATTTCGGTCTGACCTGTAAAATATGTGACTCCTGGGTACGAAAAAC
+GGATATAGGTCGCCATGGTTCTTGTGGATTATGACTGGCATAAGGGTCGTGCGACGTTCC
+CTGATAGTGATTGCGTAACGCGTTTTTTACTGCCGCCACGCTGATCTTCGTTATTGGCGT
+TAAAAAAACAGAAAATGTTTCCCCTTCGCTAACGACCGTATCCAGATGCGGATTAAACTG
+GTGTTGTAGCGTCCAGACGCGCGGATAATTATAGGTGGTATCGTTTTTGTTATCCTGCGA
+ATAGGCTTGATGAAAGTCGAATTCGCCGCGGGCCGGATCATATAATCCCTGCTTTTTCGC
+AAAGCTTACTAACGTTGGTGACGCCATATAATTCGCGTTATCATTCGGATCGTAATGGCG
+TAAACGTCCCTGATTGGCGGAAACGAAATAGCTATCTGCCGGAAGTCGTACTGCCAGCCA
+TTGATGTCCGCTTCCCGTCTCCAGATACCATATCTCTTTGCTATCAATAAACGCGACGCC
+GAAACCTTCGCCCGCGCCTTTTTGTTCAATAATATCTCCCAGTAATTTGGCGCCCTGACG
+CGCCGATTGCGCCACTGGCAGGATCACGGACTCAATGGCGTCTTCCGTGATTCCCGTTTT
+TGTCACGTAAGGATCGGCAGCCAGCGCCGCTCTGCCGTTGTAAATGGTTTCCGTTGCGCT
+CATTCCGACGCCCGCCGAATTGAAACCGGCTTCACCCATGGCGTTATCGTTAGTATCAAA
+GTCATGAATCGCCGTATAGCGCATCGCTGTCTCCGGAAGCGGCCAGCTAAAATTGTTGCG
+ATGTGCTTTATACTCGCCTTGTTGATGAAACGCGACGGGATGAATAACCTTATGCTTGGC
+GTTATTTGCCGAGCCATCCTCGTTGCGCGCGATAATAAAGGAGCCGTCAGCCGAAGCCTG
+ATTGCCTACCAAAAGGGTAGTACAGGCGATGACTTTACCCATACCCAGCAGCGTAACGGC
+GAAAGCAAGATACTTTTTCATAAAGGTTCCCACTGAATAACGCGTTATGGGATGAATTGA
+CCCTGGATTGGAAACCGAGAAAGTGATCGAGCCAGCAATATTCTTTACCGGCATCCTTTA
+TTTTCTTTTTATTGAGGTTGTATTGATAACCACAGCCCTGTGGCAGGGAAGGGGAACAGA
+ACCTGTACTGACCTTAGCTATCACCGCTATCAGGCAGACGAACCGAAAAGATATTATGTT
+CATCGGCATAGCGGTAAGATGCCGAGCCACCGTGCAATAGGGCAATCGCGTTAACTAACG
+ATAACCCCAGGCCGAAACCGGCAGTGTAGCGGGCATTATCTCCTCGCCAAAAACGCCGGA
+AAAGCTTATCCGCATCGGCGGTGGGGCTGCCCGGATTAGCGACCCGAATTTCTGCAACGT
+TATCATCATAAGCGCTTTCAATACGTATCACGGCGTTTTCATCAGAATAACGGATGGCAT
+TCGTCAGCAGGTTTGAGAGCACTCTTTGTAATAATATTTCGTCAGCCCATACCGTTCCCT
+GACATTGATTTATAAAACAGATGTGCTTCTCTTCGGCAAGGGGGCTAAGATAATCCAGCA
+TATTTTCGACCAGCGCATTGAGCGAAACAGGCTGTTTTTTTACCGCTATATTCTGGTGCT
+CCGCGCGTGCCAGAAAGAGAATATTTTCTGTCAGTCGCGACAGTCCCTCCAGCTCTTCAA
+TATTATCGACAAGGGCTTGTTGATACTCTTCGGCGCTGCGTTCCTGACTCAGCATAACCT
+GATTCTTCCCCAGTAAAATATTAACCGGCGTGCGCAGCTCATGCGCCAGATCGTCGGCAA
+ATTGGTTCAGGCGTTCAAAATCGTCGGAAAGCTTCTGGCGCATGGTATTTAGCGCTTGCC
+CAAGCGGCCTGAGCTCGACGGGTAACGCCTGTTCCGCCAGCGGCTGGCGAAGTGTGCCGC
+TATCTGTCGCCGCGGTGAGTCGGCTGAGCGACGTAATGGCCCGCAGCCCGTTTCTGATGA
+CTAATGGACTGAGCGCCGAACAGACGAGGATCGCGATAAGGCTAATCAGCAAACTGTTGC
+GGCGATATTGCGCCAGCATTTGCCGCCTTTCCGTCGCCAGCCTGGCAATAGTAAGGGTCA
+GCGGGTTATCGCCGCTTCTGGCGTTTACTCGTACCGCGGTCAGCTCCGTGCCTTGTACCG
+CCTGGCGAAATAAGGTTTCGCGGGTGATGTTTTTAGCCAGCGGAATCTCGTTAAAGCGTT
+GGTCGGGGATGCCGCTATGATTAATCGCAACATTATGGCCTGTTGCTGAGTGGATCAATA
+AGATATCCTGCTTCGTATCCACCATCCGATTGAAATAGAGCGGCAGATTTTCCGGCCTGG
+CGCCATCCAGTAACAGTTGCTGCATTTGCGCCGCCCGATTTATTAGCGTCATATCATCCC
+GATACGTTAATTCTTTGCTCAGCGCGTTATAGAGCGTCCAGCTAATGCCGGTACAGGCGA
+GGATAAGTATGGCGATAAAAGAAATTGTCAGGCGCAGCGTCATTGATAACTTAACCATTC
+TGCGACGTTTCCGCCTGTAATCGATAACCCATCCCCTGGACGGTCATAATGAGCTTCTTT
+TCAAATGGATCGTCTACTTTGGCGCGCAGCCGACGAATCGCGACATCAACGGTGTTGGTT
+TCACTATCAAAGTTAATTCCCCAAACTTCGCTGGCGATCGCGGTTCGGGGCACGATTTCC
+CCTGCCCGGGACGCCAGTAACCAGAGGAGCAGGAATTCTTTGCGGGTCAGGGAAATCGGT
+TTGCCATTTCGTAACACCGATTGCTTTGTGGCATCCATGTCCAGACCATTGATCGTCAGT
+CGGGTAAAGACCGGGACATGCTGTCTGAGTTGAGCTCTCACCCGGGCCAGCAGTTCGGCG
+AAGGAAAAAGGCTTAACAAGGTAATCATTAGCGCCCGCCTCAAGACCTTTGACGCGATCC
+TCAACCGAGTCGCGCGCCGTCAGGCAAATAACAGGGGGCTGATATGCAGTGCGCAACGCG
+CGTAAAACCTGCCATCCATCAAGCCCCGGCAGCATAATATCAAGAATAATCAATGAATAA
+TGTTCCTGAAGGGCTAGGTGTAATCCGTCTCGTCCATCACAGGCATAATCAACCACATAG
+CCTGCCTCCGTGAGTCCCTGACGTACCCACTCAATGGTTTTCTGGTTATCTTCAATCAAT
+AAAATCTTCATCAACGCAGTATGCCATAGGCTTGTTAGCGAATCCGTAAATCTCCAACAA
+GATGACATAATTGTCATGTCCGTGTAAGGTTAATCCTGGACGCGCCAGATATATTTTCCT
+GCATCAATACCGTAAAGGAGTGAAGCATGAAACGATATATACTGGCTACCGCGATAGCGT
+CTCTTGTTGCAGCCCCGGCAATGGCGCTGGCCGCTGGCAGCAATATTCTCAGCGTACATA
+TTCTCGATCAGCAAACAGGCAAACCAGCGCCCGGCGTGGAGGTGGTACTGGAGCAGAAAA
+AGGATAACGGATGGACGCAATTAAACACCGGGCATACCGACCAGGATGGACGAATTAAAG
+CACTGTGGCCCGAAAAAGCTGCCGCGCCGGGGGATTATCGCGTTATTTTTAAAACCGGCC
+AGTATTTTGAAAGTAAAAAACTGGACACGTTTTTCCCGGAGATTCCCGTCGAGTTTCATA
+TCAGCAAAACGAATGAGCACTATCATGTGCCGCTGTTATTAAGTCAGTATGGTTATTCAA
+CCTATCGCGGGAGCTAATTTAGAGCCTATCCTATTAGGGCTATTTTACTTGCCATTTTGG
+TCCTGGGCAGTGCTCGCCAAAACGCGTTAGCGTTTTGAACGCCGCTTGCGGCGGCCCGAA
+GGGCGAGCGTAGCGAGTCAAACCTCACGTACAACGTGTACGCTCCGGTTTTTGCGCGCTG
+TCCGTGTCCAAACAGGCTGCGCCAATAACGCCTGGTGGGACAGGCTCTTAGATTTTATTA
+ATCGCCGGGATTTATGGCGAGCAAACATCGCGGCGGGAATAAAAATCTTCAGCGTATCGA
+CTCTCCTCCCACAAGCGGTGGTTATCCCGCTTGTGGGTATGAGTGACGGTTAAACAGGCG
+CTTCCATCTCAAGTCTGACCGGATGAAAACGGCGTTTGAAATAAATCAGGCCATGCCCCT
+CCTGGCTAAGAATAATATTTTTGATCGCCACCAGATACACCAGATGCGTGCCAATGGTTT
+GTACCTCGCTGATCTCGCCTTCAAGACTGGCCAGCGCGCCGTTAAGTACCGGCTGGCCCA
+GCGGCCCGTTTTGCCAACATGGCTGGTGAAAACGCTCCTCCATCGCCATCCCCGTCATAC
+CGGCAAAGTGGCGCGCCATCAGCTCCTGCTCATGGTTAAGTACATTAATGCACAGCCTGC
+CGTTGCCCTGAAAAACGGGGTTCATGGCGCTATTGGCATTAATACATACCATCACGGAGG
+GCGGCGTATCAGTGACTGAGCAAACCGCTGTTGCGGTGATACCGCAGCGTCCGGCGTGAC
+CCGCCGTGGTTACGATGTTGACCGCTGCCGCCAGACTTGCCATCGCATCGCGAAAACGCA
+GACGTTGTTCATCTACTTGCATGAGAACCTCCTGCCGCGTTATTTCAGCAGCTTATCCAG
+TTGATTGATGTCGTCGTTATTGTGCAAATGCGAAACCGTCCAGCCATTCTGATCGTATTC
+GGAGAGGCAGCGATCGACCATTGCCATCATCTTATCCATATTGCCGGAGCTCTGGGCCTG
+ACGCAGACACTGCAGACGAATTTCATCCTGGCTGCCCGAGTAGTTAATCTCGTACAGCTC
+ATGGCGACCGCCAAACTCGCTGCCGATGGCATCCCACATCAATTTAAGAATTTTGATACG
+TTCAACATGGTCCATTCCGTTAGAGCCGCGTACGTATTTCGCCAGGTACTGGTCGATTTG
+CGGATTATTCAGATCGCGGGCGCTGGAAGGCAGGTAAATCAGGCCGCTGGTAACGTTACG
+TTCAATAATATTTTTAATTTTCGCGTAGGCCATTGGGGCCATCACACGATAGGTTTGCAG
+CGCGGCGTGGTCCGGTAGCCAGGCGCCGTTTACCCACGGGGTTGCTTCAGAACACATAGA
+ATCGCTCAATGCCCAGAACATATTGCGCCAGGCCACGACTTCGCCGAGATCGGCCTGCAC
+GCCCCGGAACTCTACGGTACCCGTACATTCGAGCGATTTTTTCAGCAGCGCGGTAATGAA
+ATCAAGTTTTACCGCCAGACGAACACAGGCTTGCAGTGGATACATACGGGCAAAGCCGCC
+TTCCATCGTCCAGCGACGACAACGATCGAAATCACGGTAAATTAATACGTTTTCCCACGG
+GATCAGCACCTTGTCCATCACCAGAATGGCATCGTTTTCATCAAAACGGCTGGAGAGGGG
+ATAATCAAACGGCGAGCCCGTCGCGCCCGCGACCATTTCATACGAGGCGCGCGAAATAAG
+TTTTACGCCTTCGGCATCCATTGGCGCGACAAACATCAGAGCAAAATCCGGGTTTTCGCC
+CATCACCTGGGCTGAGCCGAAACCAATCATGTTGTAGTGAGTCAGGGCGGAGTTAGTGGC
+GACAACTTTCGCCCCGCTGACAATAATCCCGGCGTCCGTCTCTTTCTCCAGCTTGATATA
+GACGTCTTTCACTTCGTCGGCAGGTTTGTGGCGGTCAATGGGCGGGTTGACGATTGCATG
+GTTAAAGTACAGGCCGGTCTCCTGAATACGGGTGTACCAGTTACGGGCGTTCTGCTCAAA
+CTGGCCGTAGAAGGCTGGGTTAGCGCCCAGAGCGCAGCCAAAGGCGGCTTTGTAATCCGG
+TGTGCGTCCCATCCAGCCGTAACTCAGGCGTGACCACTCGGCGATAGCATCACGCTGTTG
+GCGCAGATCGTCTGCGCTTTTCGCCACGCGGAAAAATTTATGCGTATAACCGCCGCTGCC
+GGTATCGGTATTCCAGCACAGGGTGTAAGCGGGAGGGGATTCCCGTGTCGGCGGCGTGGG
+AAGGTAAGAATACTATGCTTCCGCTTCGCTATCAGGATGCTGGCGCCCCAGAGCAATAAG
+ATCGTCCAGCAGCAGCATCAATTGCTGTGTTTTTTCGGGCGTGAAATCGGCCTCAATTTT
+TCGATAAGCCTCTTCTACCTCGCTCCGGGCACGGGCGTACAACGTTTGTCCCTGCTCCGT
+CAACATGACATATAACTTACGCTGATCGTTAACCGGCTTGAGTCGCAACACCAGTCCGTC
+TCGCTCCATGCGCGTCAATATTCCGGTCAGACTTGGACGCAAAATACAGGTACGAAAGGC
+CAGCTCGTGAAAATCCATAGAGGGGCTATCGGCCAGGATTCGCACAATGCGCCATTGCTG
+GTCGGTCAGATTGTGGCTTTTAACGATGGGGCGGAAATAGGTCATTGCCGCTTCGCGCGC
+CTGAAGCAAGGCGATGGTTAATGAATCATGCATAAGCGTTTCTCTTTTGCAGAATTATTA
+ATACCTGAATAATCGTGTTTACCGATGTGAGCTATGACATCTGTTTTATGTCCAAAGTTT
+AATAGAAACAAGGGGTTTTATTTAACTATTTGATATATATGTATTTAATAATAAATTTGT
+GAAAATATTGTTAATCACATCATAAATACTTTACTTAAGCTTGCTAAATGTACAGCGAAA
+GCATAAATCTAATCATTAATATGTTAATGAAATCACAGCCCGTTAAATCGGCCTGAGGAG
+TTTATGTATGAAGGGTACTGTTTTCGCCGTTGCGTTAAACCATCGCAGCCAGCTTGATGC
+CTGGCAAGAGGCTTTCTCTCAGCCTCCCTATAATGCGCCGCCTAAAACCGCAGTGTGGTT
+CATCAAGCCGCGTAATACGGTGATTCGTCACGGCGAACCCATTCCTTATCCGCAGGGAGA
+AAAGGTACTGAGCGGCGCGACAGTGGCGCTCATTGTGGGGAAAACCGCCAGCCGGATACG
+CCCTGAAGCGGCGGCGGACTATATCGCCGGGTATGCGCTGGCTAACGAGGTCAGCCTGCC
+GGAAGAGAGCTTTTATCGCCCGGCGATTAAAGCGAAATGTCGCGATGGCTTTTGCCCGCT
+GGGTGAAATGGCGCCGCTGAGTGATGTGGATAATCTCACCATTATCACTGAAATCAACGG
+ACGAGAAGCGGACCACTGGAATACTGCCGATTTACAGCGTAGCGCCGCACAACTGCTTAG
+CGCGTTAAGTGAGTTCGCTACACTTAACCCTGGCGATGCGATCTTACTTGGTACGCCGCA
+GAATCGCGTTGCGCTGCGTCCCGGCGATCGGGTGCGTATTCTGGCGAAAGGTTTACCCGC
+GCTGGAAAATCCGGTTGTCGCAGAAGATGAATTCGCCCGCCACCAGACGTTTACGTGGCC
+GCTGTCAGCGACGGGAACGTTATTTGCGCTGGGGTTGAACTACGCCGATCACGCCAGCGA
+GCTGGCATTTACGCCGCCGAAAGAGCCGCTGGTATTTATCAAAGCGCCAAACACCTTTAC
+CGAACATCACCAAACGTCGGTGCGCCCGAACAACGTCGAATATATGCACTACGAAGCCGA
+GCTGGTCGTGGTGATTGGCAAAACGGCGCGTAAGGTGAGCGAAGCCGAAGCCATGGAGTA
+TGTGGCCGGTTACACCGTCTGTAACGACTACGCGATCCGCGACTATCTGGAAAACTACTA
+CCGTCCGAATCTGCGGGTAAAAAGCCGCGACGGCCTGACGCCGATAGGCCCGTGGATTGT
+GGATAAAGAGGCGGTTTCTGATCCGCACAACCTGACGTTACGCACCTTTGTCAACGGTGA
+GCTGCGGCAGGAAGGGACGACCGCCGATCTGATCTTCAGCATCCCGTTCCTGATTTCTTA
+TCTGAGCGAATTTATGACGTTGCAACCGGGCGACATGATTGCCACCGGTACGCCGAAAGG
+GCTGTCCGATGTGGTGCCGGGGGATGAAGTTGTCGTTGAAGTAGAAGGCGTGGGTCGCCT
+GGTTAACCGAATCGTCAGTGAGGAGAGCGCAAAATGAAGAAAATAAATCATTGGATTAAC
+GGCAAAAACGTTGCAGGTAACGACTACTTCCAGACCACTAACCCGGCGACCGGTGATGTG
+CTGGCGGAAGTAGCCTCCGGCGGTGAAGCAGAAGTGAACCAGGCTGTCGCGGCGGCAAAA
+GAGGCGTTCCCGAAATGGGCCAACCTGCCGATGAAAGAGCGCGCGCGCCTGATGCGCCGC
+CTTGGCGACCTGATTGACCAGCATGTGCCGGAAATCGCGGCGATGGAAACCGCCGACACC
+GGCCTGCCTATTCACCAGACTAAAACGTGCTGATCCCGCGCGCCTCGCATAACTTCGAAT
+TCTTCGCCGAAGTGTGCCAGCAGATGAACGGCAAGACCTATCCGGTTGACGATAAAATGC
+TCAATTATACGCTGGTGCAGCCCGTCGGCGTCTGCGCGCTGGTGTCGCCGTGGAACGTGC
+CGTTTATGACCGCGACTTGGAAAGTTGCGCCGTGCCTGGCGCTGGGTAACACCGCGGTGC
+TCAAAATGTCCGAGCTGTCGCCGCTGACTGCCGACAGGCTGGGCGAGCTGGCACTGGAGG
+CAGGAATTCCGGCAGGCGTGCTGAACGTGGTGCAGGGCTACGGCGCGACGGCGGGCGATG
+CGCTGGTACGCCACCATGACGTGCGTGCGGTGTCGTTTACCGGCGGTACCGCCACCGGTC
+GCAATATCATGAAAAATGCCGGGCTGAAAAAATACTCGATGGAGCTGGGCGGCAAATCGC
+CGGTGCTGATTTTTGAAGACGCCGACATTGAGCGCGCGCTGGACGCCGCGCTGTTCACCA
+TCTTCTCGATCAACGGCGAACGCTGCACCGCTGGGTCGCGCATCTTTATCCAGCAGAGCA
+TTTACCCTGAGTTCGTGAAGCGCTTTGCCGAACGCGCGAATCGCCTGCGTGTCGGCGATC
+CGACCGACCCGAACACCCAGGTCGGCGCGCTGATTAGCCAACAGCACTGGGAGAAAGTCT
+CCGGTTATATCCGCCTCGGCATTGAAGAGGGGGCAACGCTGCTGGCGGGCGGTGCGGAAA
+AACCCACTGACCTGCCTGCGCATCTGAAAGGCGGTAACTTCCTGCGCCCAACCGTGCTGG
+CCGATGTCGACAACCGTATGCGCGTTGCGCAGGAAGAGATCTTTGGGCCGGTCGCCTGCC
+TGCTGCCATTCAAAGACGAAGCGGAAGGGTTACGTTTGGCGAACGATGTGGAATACGGTC
+TGGCCTCTTATATCTGGACCCAGGACGTGAGCAAAGTGTTGCGCCTGGCGCGTGGGATTG
+AAGCCGGCATGGTCTTCGTCAACACCCAGAACGTCCGCGACCTGCGCCAGCCGTTCGGCG
+GCGTGAAAGCCTCCGGTACCGGGCGCGAAGGCGGCGAATATAGCTTCGAAGTGTTTGCGG
+AAATGAAAAACGTCTGCATCTCAATGGGCGACCATCCTATCCCAAAATGGGGAGTTTGAT
+ATGGGCAAGTTAGCGTTAGCAGCAAAAATTACCCACGTGCCGTCGATGTATCTTTCTGAA
+CTGCCAGGAAAAAATCACGGTTGTCGTCAGGCAGCCATTGATGGGCATATTGAAATTGGC
+AAGCGTTGCCGCGAAATGGGCGTTGACACCATTATCGTATTCGACACCCACTGGCTGGTG
+AATAGCGCTTACCACATTAATTGTGCCGACCATTTCCAGGGCGTCTATACCAGCAACGAA
+TTGCCGCACTTTATTCGCGACATGACCTATGACTATGACGGTAATCCGGCGCTCGGCCAT
+CTGATCGCCGACGAGGCGGTCAAACTGGGCGTGCGCGCCAAAGCGCACAACATCCCGAGC
+CTGAAGCTGGAGTATGGCACGCTGGTGCCGATGCGCTACATGAACAGCGACAAGCACTTC
+AAAGTGGTCTCCATCTCGGCGTTCTGCACTGTGCATGATTTTGCCGACAGCCGCAAACTG
+GGCGAAGCCATTCTCAAGGCGATTGAGAAATATGACGGTACCGTAGCGGTATTCGCCAGT
+GGTTCTCTGTCGCACCGTTTTATTGACGACCAACGGGCGGAAGAGGGGATGAACAGCTAC
+ACCCGCGAGTTCGATCATCAAATGGACGAGCGCGTGGTCAAGCTGTGGCGCGAAGGCAAA
+TTCAAGGAGTTTTGCACCATGTTGCCGGAGTACGCCGACTACTGCTACGGCGAAGGCAAC
+ATGCACGACACGGTCATGCTACTGGGAATGCTGGGGTGGGACAAATACGACGGCAAGGTG
+GAGTTCATCACCGACCTGTTCGCCAGCTCCGGTACCGGCCAGGTAAACGCTGTTTTCCCG
+CTGCCTGCGTAAGGGGGGTTTATGCCGCACTTTATTGCTGAATGTACTGAAAATATTCGC
+GAGCAGGCTGATTTACCAAGCCTGTTCAGCAAGGTAAACGAGGCGCTGGCCGCCACCGGG
+ATTTTCCCCATCGGCGGTATCCGCAGTCGCGCCCACTGGCTGGATACCTGGCAGATGGCT
+GACGGTAAGCATGATTACGCGTTTGTGCATATGACGCTGAAAATCGGCGCCGGGCGCAGC
+CTGGAGAGCCGTCAGGAAGTCGGCGAAATGCTGTTTGGGCTGATTAAAGCCCACTTCGCC
+GACCTGATGGAGAACCGCTATCTGGCGCTGTCGTTTGAGATTGCCGAGTTACATCCAACG
+CTCAATTACAAACAAAACAACGTACACGCGTTATTTAAATAGCACACTCTTTCGCCCGGT
+GGCGCTGCGCTGACCGGGCCTACAAAAAAACGATGCACGAAGCAGTACCGAACCGTAGGC
+CGGGTAAGACGCACCCGCGTCGCCACCCGGCGCAGCAGCACCGAATGAGGTAACAGGAAG
+CAACTATGCTCGATAAACAGACCCATACCCTGATCGCTCAGCGACTTAATCAGGCTGAAA
+AACAGCGTGAACAGATTCGCGCAGTGTCGCTGGATTATCCCAACATCACTATTGAAGATG
+CCTATGCCGTACAGCGTGAATGGGTCAATATCAAGATTGCCGAAGGGCGCACGCTCAAAG
+GCCACAAAATCGGCCTGACCTCAAAAGCGATGCAGGCCAGCTCGCAAATCAGCGAACCGG
+ATTACGGCGCGCTGCTTGACGATATGTTCTTCCATGACGGCGGAGATATCCCCACCGACC
+GTTTTATCGTCCCGCGTATTGAAGTGGAGCTGGCGTTCGTGCTGGCGAAACCGCTGCGCG
+GCCCTCACTGCACGCTGTTCGACGTCTACAACGCCACGGATTATGTGATTCCGGCGCTGG
+AACTGATTGACGCCCGCAGCCACAACATCGACCCGGAAACCCAGCGCCCGCGCAAAGTGT
+TCGACACCATTTCCGACAACGCCGCCAACGCCGGGGTGATCCTCGGTGGTCGCCCCATCA
+AACCAGACGAGCTGGATCTGCGCTGGATCTCCGCGCTGCTCTATCGCAACGGCGTGATCG
+AAGAAACCGGCGTCGCCGCAGGCGTGCTGAATCATCCGGCCAACGGCGTGGCGTGGCTGG
+CGAACAAGCTTGCCCCCTACGATGTCCAGCTTGAAGCCGGGCAGATCATCCTCGGCGGCT
+CGTTCACCCGCCCGGTGCCGGCGCGCAAGGGCGACACCTTCCATGTCGATTACGGCAACA
+TGGGCGCGATCAGTTGCCGGTTTGTGTAAGGAAAAAACGATGAAAAATGCTTTCAAAGAC
+GCGTTAAAAGCGGGGCGCCCGCAAATCGGTTTGTGGCTGGGGCTTGCCAACAGTTACAGC
+GCTGAACTGTTAGCGGGCGCCGGCTTCGACTGGCTACTGATTGACGGTGAACACGCGCCA
+AACAACGTGCAGACGGTGTTGACCCAGTTGCAGGCGATTGCGCCTTATCCCAGCCAGCCG
+GTGGTGCGTCCGTCATGGAACGATCCGGTACAGATTAAGCAACTGCTCGACGTCGGCGCG
+CAAACGCTGCTGATACCGATGGTGCAGAATGCCGATGAAGCGCGAAACGCCGTGGCGGCT
+ACGCGTTATCCGCCTGCCGGTATTCGCGGCGTGGGCAGCGCGCTGGCGCGGGCATCGCGC
+TGGAATCGCATTCCGGACTATCTCCACCAGGCCAACGACGCCATGTGCGTACTGGTGCAG
+ATTGAAACGCGTGAGGCGATGAGCAATCTGGCGTCAATTCTCGACGTGGATGGCATTGAC
+GGCGTGTTTATTGGCCCGGCGGATCTCAGCGCCGATATGGGCTTTGCCGGCAATCCGCAG
+CACCCGGAAGTGCAGGCGGCGATTGAGAACGCCATCGTGCAGATACGCGCGGCGGGGAAA
+GCGCCGGGGATTCTGATGGCCAATGAAGCACTGGCGAAACGTTATCTGGAACTGGGGGCG
+CTATTTGTCGCCGTCGGCGTTGACACCACGCTGCTGGCGCGCGGAGCGGAGGCGCTGGCG
+GCGCGCTTTGGCGCAGAAAAAAAACTGTCCGGTGCGTCCGGCGTCTATTAAGCCTGGGCC
+GGTAAGCGCAGCGCTACCGGGCAACCGTAGTACCCTACAAAATTCCCATCAGAGGAAAAA
+AAATGAGCGACACATCATCTGCACTTCCGGAAAGCCCCGAGTCTGTCGGTTCGCACAACG
+CGCTCAGCACGGGTCAACAAACCGTCATAAATAAACTGTTCCGCCGACTGATCGTATTTT
+TATTCGTGTTGTTTATCTTCTCGTTTTTAGACCGTATCAACATCGGTTTTGCCGGGTTGA
+CGATGGGGCAGGATCTGGGGTTAAGCGCCACCATGTTTGGTCTTGCCACGACGCTGTTTT
+ACGCCACCTACGTCATTTTCGGCATTCCCAGCAACGTGATGTTGAGCATCGTCGGCGCCC
+GCCGCTGGATTGCGACCATTATGGTGCTATGGGGCATTGCATCTACCGCCACGATGTTCG
+CGGTGGGACCGAAAAGCCTGTATGTGCTGCGAATGCTGGTGGGCATTACCGAAGCGGGCT
+TTTTGCCAGGAATATTGCTCTATTTAACCTACTGGTTCCCGGCATTTTTCCGCGCCCGCG
+CCAACGCATTATTTATGATTGCCATGCCGGCCACTACCGCGTTGGGGTCAATTGTCTCCG
+GCTATATTTTATCGCTGGACGGCATATTCAATCTGCATGGATGGCAGTGGTTATTCCTGT
+TGGAAGGATTTCCGTCAGTTTTGTTAGGCATTATGGTCTGGTTTTACCTGGATGATACCC
+CGGCAAAAGCCAAATGGCTGACGGCAGAGGATAAAAAATGTTTGCAGGAGATGATGGATA
+ATGATCGCCTGACGCTGGTTCAGCCTGAGGGGGCCATCAGCCATAACGCCATGCAGCAGC
+GTAGCCTGTGGCGCGAAGTATTCACGCCAATTGTACTGATGTATACGCTGGCCTATTTTT
+GCCTTACCAATACGCTTAGCGCCATTAGTATCTGGACGCCGCAAATCCTGAAAAGTTTTA
+ATGAAGGCAGCAGCAATATCACCATCGGCCTGCTGGCGGCGATCCCGCAGATTTGTACTG
+TTCTGGGCATGATTTACTGGAGCCGCCATTCGGACAAACATCAGGAGCGTAAACACCACA
+CTGCGTTACCGTTCCTGTTTGCCGCCGCGGGCTGGCTGCTGGCGTCGGCGACCGACCGTA
+ACCTGATCCAGCTCCTGGGGATCGTGATGGCATCCACGGGTTCCTTTAGCGCGATGGCGA
+TCTTCTGGACCACGCCGGATCAGTCGATCAGTTTACGCGCCAGGGCGATAGGCATTGCGG
+TCATCAATGCCACCGGCAATATTGGCTCCGCGCTCAGCCCGGTTATGATTGGCTGGCTAA
+AAGATATCACTGGTAGCTTCAATAGCGGACTCTGGTTTGTCGCTTCTCTGTTAGTCGTCG
+GCGCCGCCATTATCTGGCTCATTCCCATGAAAGCATCGCGTCCGCGCGCCACCCCTTGAG
+GAGAAACTATGTGCCAACGTGCGATCGCCAATATTGATATCAGCAAAGAGTATGACGAAA
+GCATGGGCAGTAACGATGTGCATTATCAGTCGTTTGCTCGTATGGCGGATTTCTTTGGTC
+GTGATATGCAGGCGCATCGCCACGACCAGTTTTTTCAAATGCACTTTCTTGATACCGGGC
+AGATTGAGCTACAGCTCGACGATCATCGCTATTCGGTGCAGGCGCCGCTATTTGTGCTAA
+CGCCGCCCTCGGTGCCGCATGCTTTTATTACCGAATCGGATAGCGATGGTCATGTTCTGA
+CGGTACGCGAAGAGCTGGTTTGGCCGCTGCTGGAAGTGCTTTATCCCGGCACCAGAGAGG
+CCTTCGGCCTGCCGGGAATCTGCCTGTCGCTGGCGGATAAACTCAACGAGCTGGCGGCGC
+TCAAACATTACTGGCAGCTAATTGAGCGGGAGTCCACGGAACAACTGGCTGGCTGCGAAC
+ATACCTTGGTACTACTGGCGCAGGCGGTATTTACCTTGCTGTTGCGTAATGCGAAGCTGG
+ACGATCATGCCGCAACCGGGATGCGCGGTGAACTGAAACTTTTTCAGCGCTTTACCCTGT
+TAATTGACAACCACTTCCATCAGCACTGGACGGTGCCCGATTATGCCTGTGAGTTGCATA
+TTACCGAATCTCGTTTGACCGATATTTGCCGACGTTTTGCTAATCGCCCGCCTAAACGCC
+TGATTTTTGATCGGCAATTACGCGAGGCGAAACGACTGCTGCTTTTTTCCGACAATGCTG
+TCAACGAGATCGCCTGGCAATTAGGTTTTAAAGATCCGGCTTATTTCGCCCGTTTCTTTA
+ATCGCCTTGCTGGCTGTTCTCCTTCGCAGTTTCGCCAACGTGAAGTTCCTTCTTTTCTCA
+ACTAAGAAGAGTAAAAACATGATGAAAAAAAGCGTCGCTATGCTGGCGGTTTGTATGCTG
+GCGCAAAGCCACCTTGCCATTGCTGCCGGTGCTCCTGCGCCTCAAGAGATCAACATTGTT
+TTACTGGGCACCAAAGGCGGGCCTTCTTTGCTCAATACAGCCAGACTACCGCAAGCGACG
+GCGCTCACTATCGGCGATAAGATATGGCTGATAGATGCCGGCTACGGCGCCAGTCTGCAA
+CTGGTGAAAAATGGCATTCCACTGCGCAACATCAATACTATTTTGCTCACCCATCTGCAC
+AGCGACCACATACTGGATTATCCTTCCTTGCTGATGAATGCCTGGGCAAGTGGCCTGAAA
+GACCATACCATACAGGTTTATGGCCCGCCGGGAACCCAGGCGATGACGAAGGCTAGCTGG
+AAGGTCTTTGACAGGGATATCACGTTACGCATGGAAGAAGAGGGGAAACCCGATCCGCGC
+AACCTGGTTAAGGCGACCGATATCGGCCAGGGCGTCATCTATAAAGATGAACTGGTCACA
+ATAAGCGCGCTGAAAGTGCCTCATTCCCCTTTCCCGGACGGTGAAGCGTTTGCTTACCGT
+TTTGATACTCAGGGTAAGCGAATCGTCTTCTCTGGCGATACGTCCTGGTTTCCTCCGCTT
+GCAACGTTTGCCCAGGGGGCGGATATCCTGGTACATGAGGCGGTACATGTCCCTTCGGTA
+GCAAAACTGGCTAATAGTATTGGCAACGGAAAAACGCTGGCTGAAGCGATTGCGTCGCAT
+CACACCACGATTGAAGATGTCGGTAAGATTGCTCGCGAGGCCCACGTGAAAAAACTGGTG
+TTAAGTCATCTGGTGCCTGCGACGGTTGCGGATGACGTCTGGCAACAGGAAGCCATGAAA
+AATTACCCGGGCCCTGTCATTGTCGGTCATGACAATATGACGATAAGCGTACCGTAAGCA
+TCAGGGCAGGGGTAAACCAACGGGCTGACATCATGTCAGCCCGTTATGCTTTTGGCGATC
+AGCATGACGCGCAGAGCTTTTGTCTAAAACATTATTTTTTCTAAACACTACTTGCTGATT
+TTTATGCACAATAAAGGTAAGATGATTGCTCTGGTGAAATATCACTAAATAAGAATGTCA
+CGGATGGAATTTATACAGTGTTAAAAGCAATGCGTTTCTTTGTCTGCCGGCCATCAGTAA
+TATCCTCTGTACCGGCTCCTCGTTGCCAAAGTGAAGGTTAGATTAAACGAATCAAAAAAT
+ATCCGAACTGTACAATTTTTATATCAAACATATTTAACTGCAAAATACTGCAAACGTGCG
+CGAATACACTTAATCAGTAGTATGGCTAATGCATACTTTATTTCCTAAACTTTCTTATTA
+TCTATTTGAATATTTCTGGTTAAACCAAATGGACAAACGGATACCAGACACTCGAAAGGA
+TAACTGCAAGCTTCTGGTTTAGGATTGCAGTTACCAGGACAGTGGCTATTTTCTTTAAGC
+GATTTCCATAGAACAGGATTAAACCTGGTAACGTTGTAAACAGTAACGGGATAAAGTTTA
+TCGTTTATTAAGACCCCCTTATTAAAGGGGATGATAATGCTACCTGGAGGCATGTAAACA
+TCTGCTTGATACCATAAGGTCAATCTAAGATTTTTTAGGCTATGTATGCATGAGAACGAC
+ACTCCGGTAGAGGGACTTATAACTGTATCAACGACCTTCCATTCCATTACAGAAACCTTT
+TAAGTGAAATAGTCAATGGTGTAAATTACATTTTCCGCAAGCCTATTCAGGATAGATGAA
+AATCTGAGAAACATAACTCGTTGAAAACGATCGTTTTTTATTGACCACTCTATTTATATT
+GATTTTTTAATAAGTTATTTATTTTATGCTCTTATTTTGTTTACATTCTATTACATTTTT
+GTATTTTATACGTGGTGTAAATATTGGGCGGTAGTGGATGTTATAACGCTCAATTATTAA
+ACTGTAAGTGACTGTTGTATTTCTTATTTATAAATACCGCAACCTGTAAGCGCAGCGGTA
+CATTTTACCCGGCATTGACAGGGAGAAGATACGTATCAACCAGAGAGTACAAAACAGTGA
+AAGAATATATTCTTCAGGCAATAAATGATCGCTAACGTGTAAAAATAACCGACGAATCTA
+AAAAATGTGAGCGTGTGGCTGGTCTTTATTTAAACGATGATCTTCGCAATGGCGCATTAA
+TGGCTGACATTGGCGGTTCGTTGATCGGCTTGTGCGCGGTGAAAGGCTATATTTCTTCCG
+TTGCGGGAAGTATGTCAGAGGCATTCTGGTATTATACCGGGTGTATGTAAATCCGGGGTG
+GGCAGAAAGCCCACCCTCGGTTTATTGCCTTTATCGTGGATTAGGGATGCGAGATAAAGC
+GAGAAAGGCGTTGCAGCAGTAACCGGTTTTCTTCGCGCAGCCGTGAATTCTCTTCCAGCA
+GCGTTAACGCGACCGCGATCCCTGGCCAGTCGAGCGCCAGCTCCTCGCGTAAGCGTAGCG
+CGCGTTGTACCACGCTCGCTGCGCGATCGTCGAATTGCCAGTCGGCGTTATCGTCTTCGT
+AAGGCTCAATTACGCCAAGTCCGACGATTTCGTTTAGCTCCTCTTCCGTCACGCCGGTGT
+GCAAACAAAATTCGGTGATGGTAAAGGTGACAGTGATGTTAGCCATTATGCTTTCCCCCA
+TTGCTGGCGTGGGTCAAAGGACGACTGCGCGTCCGCCAGTTGTTGCCACAGGGCAGCTGT
+TTTCTCGTCAGGTTTCGGCGGCATAACGATTTTGATGATGGCATAGAGATCGCCAGTGTG
+CTTTTTACTGGCTAATCCTTTTCCTTTGATACGCAGCCGCTGACCTGCCTGGCTGCCGGG
+GGGAATGGTCAGCAAAATACGCTCTTTAAGCGTTGGCACAGACACCTTAGCGCCGAGCGC
+CGCCTCCCATGGGGCAAGCGGAAGGACGACTTCCAGATCCTGATTGACGATATCAAAGAG
+CGGATGCGGGGCAATATGGATAACGAGCCATAAATCGCCATTAGGTCCGCCGTTTTCCCC
+CGGCGTGCCCTGGCCTTTCAGTCTGATTCGTTGCCCGTTGCTGACGCCAGCCGGGATTTT
+CACATTCAATGTTTTGGGAATTTCCCGCTCCACCAGGCCGAACGCGTTATAAACGGGGAC
+GGAATAGCTAATCGTACGCTGGTGCTCTTCCAGCGTTTCTTCCAGGAATACCGCCACTTC
+AATTTCGATATCATGACCGCGTGCGGCGTGGCGGTGGTGCGAATGACGACCGTGCTGACC
+AAAAATAGACGAGAAAATATCATCAAAATCTTCGGCGTTATACGGCTGGCCTTCGTGTTG
+CTGGAACTGGCGATTAAATTGTGGATCGTTACGGTGTTGCCATAACTGGTCATACTCGGC
+GCGCCGTTGCTCATCACTCAGCACTTCCCATGCTTCAGCAACCTCTTTGAAACGGGCTTC
+GGCATCGGGTTCTTTGCTGACATCTGGATGGTACTTGCGGGCCAGTCGGCGATAGGCGGT
+CTTAATCGTCTTGAGATCGTCCGTCGGTTTCACGCCCATAATGGCGTAATAATCCTTAAG
+TTCCATAGCATCATCTCGCTAAATCAATACATACAGAAGGGACCCCAAAAAGGTTTCTCC
+ACTAAGTGTAGGGTAAACCTGAAAAGTGCGTATGAAAACACCAGTTATATCATTAGTAAG
+AATAAATTACGTTGTTCGACTATCAGAAGGTTGCGCAGCGCGCCGACATAACTTTACAGG
+GGAAAGGTTGCCAAAACCGCGCCAGTGGCTAAGATAACTCGCGTTAAACAGTGAGGGCGC
+AATGGCGAAACAACAACGGATGGGCTGGTGGTTTCTTTGCCTTGCATGTGTCGTGGTAAT
+GGTTTGTACCGCGCAACGCATGGCGGGCCTGCACGCCTTGCAGATGCAGGCGACGGCCTC
+TGCTGCGGTGGTCAGCGCTCCCTCCTCGACAGATGACGGCTCGCCGGTCACTCCCTGCGA
+ATTAAGCGCCAAGTCGCTGCTGGCGGCGCCTCCAGTACTCTTTGAAGGTGCTATCCTTGC
+GCTTTATCTACTGCTTTCCTTACTGGCGCCTGTCCGGGTCATGCGCCTGCCGTTTTCGCC
+TCCACGGGCTATTTCGCCGCCCACATTACGGGTACATCTACGATTTTGTGTCTTCCGTGA
+ATGACAGACCGGTTATTACTAACGGTTAATTACTCATTCACGGAGAAAAAATATGATGAT
+TTTATTCAGGCGGATACTGTTCTGCCTGTTATGGCTTTGGCTGCCCGTCTCCTGGGCGGC
+GGAAAGCGGCTGGCTGCGTTCGCCCGATAACGACCATGCCAGCATACGGCTACGTGCCGA
+TACGTCCGCTAACAGTGAGACCCGGCTGTTGCTGGATGTCAAACTGGAAAACGGCTGGAA
+AACCTACTGGCGCGCGCCGGGGGAAGGGGGCGTGGCACCCTCTATCGCCTGGAAAGGCGA
+CATGCCTGAGGTAAGCTGGTTCTGGCCAACCCCCTCGCGCTTTGATGTGGCGAATATCAC
+CACCCAGGGATATCACGACGAGGTGACCTTTCCGATGATCGTGCGCGGTACGCCGCCGGC
+GACCTTGCGCGGTGTGTTGACGTTATCAACCTGCAGCAATGTTTGTCTGTTGACCGATTA
+CCCCTTTTCCGTGACGCCCACTGTGCAGAATGCCGATTTTGCCCATGACTATGCGCGGGC
+GATGGGTAAAGTTCCGCTCCGCAGTGGGCTAACGGACTCGCTTGACGTTGGCTATCGCCC
+GGGAGAACTGGTGGTCACTGCTACGCGAGCGGCGGGCTGGTCATCGCCCGGGCTCTATCT
+TGACACCATAGATGACGTCGATTTTGCGAAGCCTCGCCTGCGCGTAGAGGGCGACAGGTT
+ACAGGCGACGGTGCCGGTGACGGACAGTTGGGGCGAAAAGGCGCCCGATTTGCGCGACAA
+ATCGCTGACCCTCGTGTTAGCCGATGGCGCTATCGCCCAGGAGAGCACGCAAACCATTGG
+CGCTGCGCCAGCGCAAACGCCGGACAATGCGGCGCTACCTTTCTGGCAAGTTGTAATGAT
+GGCGCTAATCGGCGGACTGATTCTTAATTTAATGCCCTGCGTACTGCCTGTTCTGGGCAT
+GAAACTTGGCTCTATTTTATTGGTAGAGGAAAAAAGCCGCTCTCACATCAGGCGACAATT
+TTTGGCTTCGGTCGCCGGTATCATTGCGTCATTTATGGCGCTGGCGGCGTTTATGACCCT
+CCTTCGCCTGTCAAACCATGCGCTGGCCTGGGGAGTCCAGTTCCAGAATGCATGGTTTAT
+TGGTTTTATGGCGCTGGTGATGTTGTTGTTTAGCGCCAGCCTGTTCGGGCTTTTTGAGTT
+CAGGCTTCCCTCATCTATGACCACGAAACTGGCCACTTACGGCGGTAACGGTATGTCGGG
+ACATTTCTGGCAGGGGGCGTTCGCCACGCTGCTGGCGACGCCTTGTAGCGCGCCGTTTCT
+GGGCACGGCGGTCGCGGTGGCGCTCACGGCGTCGCTGCCGACGCTGTGGGGGCTGTTCCT
+TGCGCTTGGCCTGGGAATGAGCGCGCCGTGGCTACTGGTCGCGATACGACCAGGGCTTGC
+GCTACGTTTACCGCGCCCCGGGCGTTGGATGAATGTCCTGCGCAGGATCCTCGGTCTGAT
+GATGCTGGGGTCGGCTATCTGGCTGGCGACGTTACTCCTGCCGCATTTCGGCTTCACTGC
+GTCAAAGAGCGCGCAAGACACGGTTCAGTGGCAACCGTTGAGTGAACAGGCAATCCAGTC
+GGCGCTGGCGCAGCATAAGCGGGTATTTGTCGATGTCACTGCGGACTGGTGTATTACCTG
+TAAAGTGAATAAATACAACGTCCTGCAAAAAGAGGATGTGCAGGCCGCCTTGCAACAGCC
+GGATGTTGTGGCGCTGCGGGGAGACTGGACGCTGCCGTCCGATGCCATTACAGATTTTCT
+GAAAACGCGCGGCCAGGTCGCCGTGCCGTTTAATCAGGTATATGGCCCCGGTTTGCCGGA
+AGGGGAGGCACTGCCCACTTTGCTGACCCGCGATGCGGTATTACAAACGTTGAAAAAAGC
+GAAAGGAATAACCCAATGAAATACATGATTGTTTTACTGCTGGCGCTGTTTTCGACGCTG
+AGCATCGCGCAAGAAACCGCTCCTTTTACGCCGGATCAGGAAAAGCAGATTAAAAATCTG
+ATCCATGCGGCGTTGTTTAACGATCCTGCCAGCCCGCGGATAGGCGCTAAACACCCTAAG
+CTGACGCTGGTGAACTTTACGGATTACAACTGCCCGTACTGCAAACAGCTCGATCCGATG
+CTGGAAAAGATTGTGCAGAAATATCCTGACGTTGCGGTCATTATTAAACCGCTGCCATTC
+AAAGGAGAGAGTTCCATACTGGCGGCGCGTATTGCGCTGACCACCTGGCGCGATCATCCG
+CAACAGTTCCTCGCGCTACATGAAAAACTTATGCAAAAGCGCGGTTACCATACGGATGAC
+AGTATTAAACAGGCCCAGCAGAAAGCAGGGGCGACGCCAGTGACGCTGGATGAAAAAAGC
+ATGGAAACGATACGCACTAATTTGCAGTTGGCAAGACTGGTCGACGTGCAAGGAACGCCA
+GCGACGATCATTGGCGACGAGCTGATTCCGGGCGCAGTGCCCTGGGATACGCTGGAAGCG
+GTGGTGAAAGAAAAACTGGCGGCTGCCAATGGCGGGTAAACTGCGGCGTTGGCTGCGTGA
+AGCCGCGGTTTTTCTGGCGCTCCTCATCGCGATAATGGTGGTCATGGACGTCTGGCGCGC
+GCCGCAGGCGCCTCCGGCGTTTGCCGCGACACCATTACATACGCTGACGGGAGAGTCGAC
+AACTCTGGCGACCTTGAGCGAGGAACGCCCCGTACTGCTCTATTTTTGGGCCAGCTGGTG
+CGGGGTATGCCGCTTTACCACGCCTGCGGTCGCTCACCTGGCGGCGGAAGGGGAAAACGT
+CATGACCGTTGCGCTCCGCTCCGGCGGTGATGCTGAGGTTGCCCGCTGGCTGGCGCGCAA
+GGGCGTTGACTTCCCGGTCGTCAATGATGCTAACGGCGCCTTATCCGCTGGCTGGGAAAT
+CAGCGTGACGCCAACGCTGGTGGTGGTTTCACAAGGTCGGGTTGTGTTCACCACCAGCGG
+CTGGACCAGCTATTGGGGCATGAAGCTTCGGCTGTGGTGGGCAAAAACGTTCTGAATATG
+CGCCGGGGTTTCCCGGCGCTAACGCGTTTACTGTAAGAAAAACCTCCGTTTTGCGAAATC
+GTTCCCGGAAAAATGATCCATTTCTGTCACACTCAGAACGATTTGATAACAACAAGAGGT
+CATAGGGATGAAAAAATCATTACTCGCTGTTGCTGTGGCAGGGGCTGTTTTGTTGTCATC
+CGCCGTACAGGCGCAGACAACGCCGGAAGGTTATCAATTACAACAGGTGCTGATGATGAG
+CCGCCATAATCTGCGGGCGCCGCTGGCGAATAATGGCAACGTACTGGCGCAGTCGACGCC
+GAACGCCTGGCCGGCGTGGGACGTTCCCGGCGGGCAACTGACGACGAAAGGCGGCGTGCT
+GGAAGTCTATATGGGACACTACACACGTGAATGGCTGGTCGCGCAGGGGCTGATACCGTC
+GGGAGAATGTCCGGCGCCCGACACGGTATATGCCTATGCGAATAGTTTGCAGCGCACCGT
+CGCCACCGCGCAATTTTTCATTACCAGCGCTTTCCCCGGCTGTGATATTCCTGTTCATCA
+TCAGGAAAAAATGGGCACTATGGACCCTACCTTCAATCCGGTGATTACCGATGATTCCGC
+CGCGTTCCGGCAACAGGCCGTACAGGCGATGGAAAAGGCGCGTAGTCAGCTACATCTTGA
+TGAGAGTTATAAACTGCTTGAGCAGATAACGCATTATCAGGACTCGCCGTCCTGCAAAGA
+GAAGCATCAGTGTTCGCTAATCGACGCGAAAGATACCTTCAGCGCGAACTATCAGCAAGA
+GCCTGGCGTGCAGGGGCCGCTGAAAGTAGGGAACTCGCTGGTGGATGCGTTTACCCTGCA
+ATATTACGAAGGCTTTCCGATGGATCAGGTCGCTTGGGGCGGGATCCACACCGATCGGCA
+GTGGAAGGTGCTGTCAAAACTGAAAAACGGCTACCAGGACAGCCTGTTTACCTCACCCAC
+GGTGGCGCGCAATGTCGCTGCGCCGCTGGTAAAATATATCGATAAGGTGCTGGTTGCCGA
+GCGCGTTAGCGCGCCGAAGGTTACCGTGCTGGTGGGGCATGATTCCAATATCGCGTCGCT
+GCTGACGGCGCTGGATTTTAAACCCTATCAGCTCCATGACCAGTATGAGAGAACGCCGAT
+TGGTGGTCAGCTTGTCTTCCAACGCTGGCATGACGGTAACGCTAACCGGGATTTGATGAA
+AATCGAGTATGTCTACCAGAGCGCCCGGCAGTTACGTAATGCGGAAGCGTTAACGCTCAA
+ATCGCCTGCGCAAAGGGTAACGCTGGAACTGAAAGGATGTCCGGTGGATGCGAACGGCTT
+CTGTCCGCTGGATAAGTTCGATAACGTCATGAACACTGCTGCAAAATAGCCGTATGCCCC
+CGCGCAGGCGGGGGCGTTTGTGTTATACGTTCTTACGTTCGATGACTTGTTCGCCCCAGA
+AGAGCGAGTCTTTGTCCGTTTTCTCAAAGGCTTTGATCAGCACCTCATCGCTACCTTCTT
+CCCATATTTTTTCTGCCAGTTTCTCGTCATAGTGAGCGACTTCAAAAATGGCTTCGGCAA
+TTTCCGGCGACGTATTACGCAGGCTTGCCCATTCGCCGACGCGGTGCGCTTTTGCTTCTT
+GAGTTGGCATTCGAATCCTCCTGTTGAAGATTAGCCGTTGAGTTTGACTGCCAGACCGGC
+GACGTATTCCCCCTGATAGCGAGCGATAGAGAGTTCCTCCTGGCTTGGTTGACGTGAACC
+GTCGCCTCCAGCGATAGTCGTTGCGCCGTAAGGCGTACCGCCGCGAACCTGGGAGACGTC
+AAACAGTTCCTGTGCGGAATAGCCTATCGGGACAATCACCATCCCATGATGGGCAAGCGT
+AGTCCAGGTCGAGGTGATGGTCTGCTCCTGGCCGCCGCCCGTTCCGGTAGAACTGAACAC
+GCCGCCGAGCTTGCCGTATAGCGCGCCGGATGCCCACAGTCCGCCGGTTTGGTCCAGGAA
+GGTACGCATCTGGCCTGACATATTGCCAAACCGGGTTGGCGTACCAAAAATAATGGCATC
+GTAATCCGCCAGCTCCTGTGGGGTGGCAACCGGTGCGTTTTGCGTTTTACCGCCAGCTTT
+TGCGAAGATTTCAGGCGGCATTGTTTCTGGCACACGCTTTATAATGACCTCTGCGCCGTC
+GACTTTCTTTGCCCCTTCCGCCACCGCGTGCGCCATGGTTTCAATGTGTCCGTACATGGA
+ATAATAGAGCACCAGAATCTTTGCCATTTGTACTACTCCTCAGATTAATCAGGTGTGTAG
+CGATTCGCTACGTCTATTTAAAGATATGCCCTCCTGTGAAGAGTGCAAATTTCAGCGCCA
+TTTCTTTGATTTATAACAATAATTAATTTGGCGACCTTTGTTGCAAAATGATACATTTTT
+AAGCGCTTTGATTTTTCCAAGTATAAGAATAACTTATTTATTTCTCATGGTTATTATTCT
+GCATATTCGGCTTCTGATGTTGCAGAATATTTCGGTAAGCGGCCTACCACGGCGTTTTTC
+ACTATGCTTAATTTTACGCGGCGTTACTGATGATATCGTTCATACGCGGCGCGAGGAGAT
+ACTCCTCATTACCTATGCAATATGATGTCTAATCTATGACGGAGGTCAGTAATGGCAAAC
+CATCGTGGCGGTTCCGGTAATTTTGCGGAAGACCGCGAAAGAGCATCAGAAGCAGGTCGT
+AAAAGTGGTCAGCACAGCGGGGGCAATTTTAAGAATGACCCGCAGCGTGCATCCGAAGCA
+GGCAAAAAAGGGGGCAAAAGCAGTAACCGTAATCGCTAGCCTGCGTCACAACAGCAAGAC
+GCTGAGCGTTTCGCGCTAAAAAGCGTCATGCGCCACCGCCGCCGGATTTCCGGCGGTTTT
+TTTGTTTATAAGCCGGATTTGGTATGCTTGCGTCCTGACGAAAAGGAGAGGGCGCATGTC
+GCAACGCACAGAGAAAAAAATCGGGAAACGTTCGCAGGCCACCGGTGCAAAACGGCAGCT
+TATCTTAACCGCCGCGCTTGCCGTTTTTTCCCAGTATGGCATTCATGGCGCGCGTCTTGA
+ACAGGTCGCCGAGCGGGCAGGCGTCTCCAAAACCAATCTGCTTTATTATTATCCCTCGAA
+AGAGGCGCTGTATGTCGCGGTAATGCGACAGATTCTGGATGTCTGGTTGGCGCCGCTCAA
+GGCGTTTCGCGCAGAATTTTCCCCTCTGGAGGCCATCAAAGAGTATATCCGTCTCAAGCT
+GGAGGTTTCGCGTGATTATCCGCAGGCGTCGCGGCTCTTCTGCATGGAGATGCTGGCGGG
+CGCGCCGCTCTTAATGGATGAACTGACCGGCGATCTAAAAGCGTTGATAGATGAAAAATC
+CGCGCTGATTGCCGGATGGGTGCACAGCGGGAAACTCGCGCCCGTTTCTCCGCATCATTT
+GATCTTCATGATTTGGGCCGCCACGCAACATTACGCCGATTTCGCCCCTCAGGTTGAAGC
+GGTAACCGGCGCGACGCTTCGCGATGAAGCCTTTTTCAACCAAACGGTCGAAAGCGTTCA
+GCGCATTATTATTGAAGGGATTCGCGTGCGTTAACCGGCTGGCGGCAGTGGGCAGCTCAA
+ATCACCCTCTTCACATTGCAGCAGCGAGGCTAAAAACGCTTCGCGTTCGTTCGTTTTATC
+GGTCAGGCACTGGCTGGCGATCATGGGTTGAACGCTGCCGCCCTCCGTACCTGAGCGAAT
+CAGCGCGCAATCGGCGTCGCGCAGGGCAATCCATGCCACCTGCGCTTTTTGCAATAGCTC
+ACGCTGCGGCGGTTGCGCACGCTTAATCGCGCTTTGATAGGTTTCGTTCAGCTTTTTATC
+TGCCGCCTGGTATTGCGCGGCGGCGCAGCGATTCATTTCCAGCTGCGTACTGGCGCTGGC
+ACACTCATCGGCCAACGCCTGACTGCTGAACAACAACGCCGCGCAGGTAAGGAAAATTCG
+TTTCATACGGTCCTCTGACGCGAGTAAAAAGGCTCCATTGACGGAGCCTTAATTAACCAC
+AGTATTAGCCAATTGTCATCAGGCTGGCATTACCGCCAGCGGCGGCAGTGTTTACGCTCA
+GCGAACGTTCAATATAGAGCCGTTCCAGCAGCATATTGCTTTCGCCGCGGGCGAACCCCT
+GTACCGACACTATCGCGCCTTCGCGGGCGGCGACGGCTTCGCACACGGTTCGCAGCTTGT
+CGGAGTCGCCGTGGAAAATCACCGCGTCAAACGGCTGCGCCATCAGCGTTTCCGCTTTCG
+CAAACTGGACACGCGCCGCGACGGCGGCGGGGAGACGTTTCGCCAGATCGCGGTGGAAGG
+CGTCGTCTGACCATAGCGCCTGACTGCCGACGGCGAGAACGGCGGCAAGCTGCGTCAACG
+CGTCCTGTTCATCATCAGCCAGGCATAACACCCGTTCACGCGGCAACAGCGTCCAGGTAT
+TACGCTCGCCGGTCGGCCCCGGTAGCAGGCGCTGCGTGCCGGCCTGCGCCAGATCGGCGA
+ATTGTCGGCAGAGCGTCTGTAGCGCCGGGCGATCCGCCGCCCATTGCGTCAGAGCGGTCA
+ACGGCGCGAGTAGCGTGGTTTTAAGCTGCGCATCCACCGGGTAACGCGCATCCTGACGAG
+TCAGCGTCGTATTGAGCGCATTGGGCGGGCGGTGTGCCAGCAGGCGGTAGAGATAGAGCG
+GCCCTCCCGCTTTTGGCCCGGTGCCGGACAGGCCTTCGCCGCCAAACGGCTGGACGCCGA
+CGACCGCGCCCACCATATTACGGTTAACGTACAGGTTGCCGACATGGGCGGAACCGGTGA
+CTTGCGCAATGGTTTCATCAATACGGGTATGTACGCCCAGCGTTAGCCCGTAGCCGGAAG
+CGTTAATCTGTTCGATAAGCTCCGCCAGTTGGTTACGGTTATAACGCACGACGTGCAGCA
+CGGGCCCGAAGACCTCTTTTTCCAGTTCTGCGAAGTTTTCCAGCTCAATAAGCGTGGGCA
+TAACAAACGTACCGGTCTGCCATTCCTGCGCGTCATCGCTGTTTTCACGCGCGGCCTGGA
+AAACCGGGCGGCCTTTGGCGCGCATCGTCTGGATATGACGTTCAATGTTGGCTTTGGCCT
+CGCTATCGATCACCGGCCCGATATCGGTCGTCAGACGGCCTGGATTCCCCATCCGACACT
+CCGCCATCGCGCCGCGTAACATTTTCAGCGTATGTTCGGCGATATCGTCCTGCAAACACA
+GCACGCGGAGCGCGGAACAGCGTTGTCCGGCGCTGTCGAAGGCGGAAGCCAGCACATCCA
+CGACCACCTGCTCGGTGAGCGCGGAAGAGTCGACAATCATAGCGTTCATACCGCCGGTTT
+CCGCAATCAACGGAATAGGGCGCCCCTGGGCGTCAAGACGCGTGGCGATGTTGCGCTGCA
+ACAACGTCGCGACCTCCGTGGAACCGGTAAACATCACGCCGCGTACACGCGCATCGGCGG
+TAAGCTGGGCGCCGACGGTTTCTCCCCGTCCCGGCAACAGTTGCACGACGCCCGGCGGTA
+CGCCCGCTTCCAGCAAAATGGCAATGCCCTGGGCGGCAATCAGCGATGTCTGCTCTGCCG
+GTTTCGCCAGAACGCTGTTACCTGCCGCCAGCGCGGCGGCGATTTGGCCAGTGAAAATGG
+CCAGCGGAAAGTTCCACGGACTGATACAGACCACCGGCCCTAACGGGCGATGCGTTTCGT
+TATCGAAATCGTCACGCACTTGACCGGCATAATAATGGAGGAAGTCTACCGCTTCGCGCA
+CTTCGGCAATGGCGTTGCTGAACGTTTTCCCCGCTTCACGCACCAACAGGCCAATCAACT
+GCTGCATTTGGTCTTCCATCAATACCGCCGCCCGCTGCAAAATAGCGGCGCGTTCTTGCG
+GCGGCGTCGCAAACCAAACCGGCGCCTGATTGACCGCGTTTTGCAACGCCTGTTCAACCT
+CGCTTTCTGTCGCTTCGCGTCCCCAGCCAACAATATCTTTCGGTTCCGCCGGGTTGATAA
+CCGGCGTCATCTCACCGTCGGCCACCGGTTGTTCCAGCACAGGTTTGGCCTGCCATTTCT
+GCATGGCGTTGCTTAACAGGGCAGAAGAAAGCGAGGCGAGGCGATGTTCATTCGCTAAAT
+CAAGTCCGGCGGAGTTTATCCGACCTTCGCCGTACAGATCGCGCGGCAGCGGAATTTTTG
+GATGCGGTATGCCAGCCTGACCTTCCTGCTGCGCCAGTTTTTCCACGGCCTCGACCGGGT
+CGGCCACCAGTTCATCGAGCGGTAGGGTGGCATCGGCGATGCGGTTGACAAAAGAGGTGT
+TGGCGCCGTTTTCCAGCAGGCGTCGTACCAGATAGGCCAGCAGGGTTTCGTGTGTTCCCA
+CCGGCGCGTAAATACGGCAGGGACGGTTAAGTTTTCCGTCCCCCACTTTACCGGTGACCT
+GTTCATACAGCGGTTCTCCCATGCCGTGCAGGCACTGGAATTCGTACTGACCCGGATAGT
+AATTTTGCCCGGCCAGATGATAAATCGCCGCCAGTGTGTGAGCGTTATGGGTCGCGAACT
+GCGGGTAGATCAGATTAGGGACGGCGAGCAGTTTTTTCGCGCAGGCCAGATAAGAGACAT
+CGGTATACACTTTGCGGGTATAAACTGGATAGCCCTCCAGCCCTTCCATTTGCGCGCGTT
+TGATCTCGCTATCCCAGTAGGCGCCTTTCACCAGACGAATCATCAGCCGACGGCGGCTAC
+GGGAGGCCAGATCGACTAAATAATCAATGACCAGCGGGCAGCGTTTCTGGTAAGCCTGAA
+TCACAAAGCCAATGCCGTTCCAGCCCGCCAGTTCGGGTTCGAAGCAGAGTTTTTCCAGCA
+GATCAAGCGAGATCTCCAGACGATCCGCCTCTTCGGCGTCGATATTGAGACCGATATCAT
+ACTGGCGCGCCAGCAGCGTCAGGGATTTCAGGCGCGGATAAAGCTCCTCCATTACCCGAT
+CGTATTGCGCGCGACTATAGCGTGGATGCAGGGCGGACAGCTTAATCGAGATGCCTGGCC
+CTTCGTAAATACCGCGACCGTTAGACGCTTTGCCGATGGCATGAATCGCTTGCTGGTAAG
+AGACCATATAGGCCTGCGCATCGGCGGCGGTTAACGCGGCTTCGCCCAGCATATCGTAAG
+AATAGCGGAACCCTTTCTCTTCCAGTTTTCGGGCATTCGCCAGCGCCTGAGCAATGGTTT
+CGCCAGTCACGAACTGCTCGCCCATTAAACGCATCGCCATGTCGACGCCTTTGCGGATTA
+ACGGTTCGCCGCTCTTGCCGATAATGCGGTTCAGCGAGCGCGAAAGATTGGCTTCGTTAT
+GCGTTGAGACCAGTCGGCCGGTAAAGAGCAGCCCCCAGGTGGCGGCGTTTACAAACAGCG
+ACGGGCTACGGCCAATATGCGACTGCCAGTTGCCATTACTGATTTTGTCGCGAATTAACG
+CATCGCGCGTAGCTTTGTCGGGAATACGCAGCAGCGCTTCCGCCAGACACATCAGCGCTA
+CGCCTTCTTGCGAAGAGAGGGAAAACTCCTGCAACAGGCCTTGCACCATACCCGCGCGAC
+CGCTGGCGGATTTTTGATTGCGCAATTTCTCCGCCAGTTGATACGCCAGTTTATGCGCCT
+GCTCAGCGACAGGCGGCGACAGGCGCGCCTGTTCCATTAGCATTGACACCGCATCGGTTT
+CCGGGCGGCGCCAGGCGGCGGTGATGGCGGCGCGAGAGACGGATTGGGGAAGAATCTGTT
+CGGCAAACTCCAGAAAGGGCTGATGCGGCTCATCCTGCGGCGCGACCGGCTCCTCGCTTT
+CATTTGCCGCGCCGGCAAACAGCGCAGGTAGCTCCGGTAGCGTATCGCTATTTTCCAGCT
+TGTCCAGATAGCTAAAGATTGCCTGTTTTATTAACCAGTGCGGCGTGCGATCGATACGCG
+ACGCGGCCATTTTGATCCGTTCGCGCGTGGCGTCGTCCAGCTTAACCCCCATCGTGGTGG
+TTCCCATACCCTCTACTCCTGTTATTCGCTCTATCTGCTAACCAATAGTTAGCGGAAAAT
+ATCCACTATATTGCAACTTTGTGCAACCGCGTTAAATGTGACCTGCGTTGCAAGCTTAAA
+AATGAATAAATTGTTAAAAAAAGAAAGTGGGAGTCTGACGGGGAAAACCATCTGGATTTA
+TTTTCTCTGCGGTAGTTAACACTTTTAAAAGGTGCAACCGCAAAAAATGTGAGAGAGTGC
+AACCTGGAGAAAAATAGTATCCCTCTGCAATCAAATTTGATGTAAATGGTGTGTTAAATC
+GATTGTGAATAACCACCGATTCCGGCAGGATACGGTCGCCCTGGTAAACATAACACCCTT
+GCCACGTTCCGGCAGGGTACAAAACGGCACGCTACGGTAGTGCCAATAAATAAATTTGGA
+GAACCTTGATGGCTATTAGCACACCGATGTTGGTGACATTCTGTGTCTATATTTTTGGCA
+TGATATTGATTGGGTTTATCGCCTGGCGCTCAACCAAAAACTTTGATGACTATATTCTTG
+GCGGTCGCAGCCTGGGGCCGTTTGTTACGGCTTTATCAGCCGGCGCGTCGGATATGAGCG
+GCTGGCTGTTAATGGGGCTGCCTGGCGCTATCTTTCTGTCGGGGATCTCTGAAAGCTGGA
+TCGCCATTGGCCTGACGTTAGGCGCATGGATTAACTGGAAGCTGGTGGCCGGGCGCCTGC
+GCGTGCATACCGAATTTAACAATAACGCGCTCACGCTGCCGGACTATTTTACCGGTCGGT
+TTGAGGATAAGAGCCGAGTCCTGCGTATTATTTCCGCGCTGGTCATTCTGCTGTTTTTCA
+CTATCTATTGCGCATCAGGTATTGTCGCTGGGGCACGACTGTTCGAAAGCACCTTCGGTA
+TGAGCTATGAAACCGCACTGTGGGCGGGGGCCGCGGCAACCATTATTTATACCTTTATCG
+GCGGGTTTCTTGCCGTTAGCTGGACGGATACCGTTCAGGCCAGCCTGATGATTTTTGCGT
+TAATCCTGACGCCGGTGATGGTTATTGTCGGCGTAGGCGGTTTTAGCGAGTCGCTGGAAG
+TGATCAAGCAAAAGAGCATCGAGAATGTCGACATGCTCAAGGGGCTGAATTTTGTCGCTA
+TTATTTCTCTGATGGGCTGGGGGCTGGGTTACTTCGGTCAGCCGCATATCCTGGCGCGCT
+TTATGGCGGCGGATTCCCATCACAGTATTGTTCATGCGCGTCGTATCAGTATGACCTGGA
+TGATTCTGTGTCTGGCGGGCGCGGTGGCGGTGGGCTTCTTTGGCATTGCGTACTTTAACA
+ATAACCCCGCGCTGGCCGGGGCGGTGAACCAAAACTCAGAACGCGTATTTATTGAACTGG
+CGCAGATCCTGTTTAACCCGTGGATTGCCGGTGTTCTGCTGTCTGCTATCCTGGCGGCGG
+TGATGTCGACGTTGAGCTGTCAGTTGCTGGTATGCTCCAGCGCGATTACGGAAGATTTAT
+ATAAGGCTTTTCTGCGTAAAAGCGCCAGCCAGCAAGAGCTGGTATGGGTAGGGCGAGTGA
+TGGTGCTGGTGGTAGCGCTGATCGCCATTGCGCTGGCGGCGAATCCTGATAACCGTGTGC
+TGGGGCTGGTGAGCTACGCCTGGGCTGGATTCGGCGCGGCATTTGGACCTGTTGTCCTGT
+TTTCTGTGATGTGGTCGCGTATGACACGTAACGGCGCGCTGGCGGGAATGATTATTGGCG
+CGGTGACGGTTATCGTCTGGAAACAATATGGCTGGCTGGATCTGTATGAGATTATCCCTG
+GCTTCATTTTCGGCAGCCTGGGGATCGTAATCTTTAGCCTGCTTGGCAAAGCGCCGACAG
+CAACGATGCAGGAACGCTTTGCAAAAGCGGACGCGCATTATCATTCCGCGCCGCCGTCGA
+AGCTACAGGCGGAATAACCGACATGTCCGATAGCATTATTGCCATCGGATATATTTTACC
+AGGCGGCGTTATACGCCTGCCTGGTCCTCTGATAAGTCCCGGACCGATTGACTGAAGGTG
+TTCAGGTAAATGAGGACGCTCTCTCAAACTATTTTTAGCCCTTGAGCGCCGTTAACGCGG
+CCGTAATACGTCTCGAGTAATCACTAACTGACCATATATGAAATCGCCTGTTAATGGTAC
+CAATAGCCTTGACGCAATAGAGTAATGACAAAAATTAAAACGAGTCAGCGTTACTGGCGT
+AAGTATGCCGCACAAAATTTTGCATAAATAATGCCGTTTTAGCGATGGGAGAGAGGACAC
+GTTAATTACTCCGTTTTAATCTTTTATATGTTGAATATTCAATGGGTTATGGGTGTTTTC
+ACCATTAATACCCATAGTAGCTAATGATTATCTTTTTTAGTCTCCTGCCAATGAAATAAT
+TGTGTAATCTTTCTGTAAGAGACTGACAATGACGCAATAATGTTTGGTTAATGTTTGGTG
+AATATATTGTTGCATTATTGATGTTTTGTGTTGTACTTAGTAGTAATAGCGGTAGTTCCC
+CGGCAGTGATGGTCACTCACTATGGAGATCGCGAATGGTAATGTCCGCACCAGGACACAT
+TGTTTACAGTAGTTACAACACCCTGTACGGACATTCTCTCTCCGGTGGTGGTCTTGTCAT
+CTTAAAAGCTCTCATCATTTCCCTTACTGTCCATACCCATGACGCCATATGTGGTGCGCG
+TAGCCGTGTGTGGCGTCGTTTCAAAAAGCAAGCTAAGGCTTACAAGGAAGCCAACCCTCA
+GATGTGTGTGCGCATAATCGCGTTCAAGAGAACGCGGGTGATGTATACCTACAACTCAAG
+GTGCTATCCATGGGAAGACAAAAAGCAGTGATCAAAGCTCGTCGTGAAGCAAAGCGTGTG
+TTGAGACGAGATTCGCGTAGTCATAAGCAACGTGAAGAAGAATCGGTCACGTCACTGGTA
+CAGATGGGCGGAGTAGAAGCCATTGGCATGGCGCGCGATAGTCGCGATACCTCTCCTGTT
+AAGGCGCGAAATGAAGCACAGGCGCATTATCTGAACGCTATCGACAGTAAACAGCTTATT
+TTTGCGACCGGCGAAGCCGGCTGCGGAAAAACATGGATCAGTGCGGCAAAGGCGGCAGAA
+GCATTGATTCATAAGGACGTCGAGAGGATCATTGTGACGCGTCCGGTATTGCAGGCTGAT
+GAAGATCTTGGTTTTTTGCCCGGTGATATCGCTGAAAAATTCGCGCCTTATTTTCGTCCC
+GTCTACGATGTCCTGCTTAAACGGTTGGGCGCGTCCTTTATGCAATATTGTTTGCGCCCG
+GAAATCGGTAAGGTAGAAATTGCCCCGTTCGCCTATATGCGTGGGCGTACTTTTGAAAAT
+GCGGTCGTGATCCTCGACGAGGCGCAAAATGTGACTGCGGCGCAAATGAAAATGTTTTTG
+ACGCGATTAGGCGAAAATGTCACGGTCATTGTCAATGGCGATATTACGCAATGCGACCTG
+CCGCGCGGTGTGCGTTCCGGGTTGAGTGATGCGTTGGAACGCTTTGAAGAAGATGAAATG
+GTGGGGATTGTGCATTTCAACAAAGACGACTGCGTGCGCTCGGCGCTTTGTCAGCGAACG
+CTCCACGCATACAGCTAATATAGCATTGACTTTCAGAGCCCGGGAGACCGGGCTTTGTTG
+TCTATAAAGCGTCCAGCAGACTCATGGACAAAAAAGGAAAATGACGCCTGTACGTGAAGG
+GAATTATTTTGTCATGTCCAGGGCATTCATTGTCCGTAATTTGCTTTCTCGGGCCTGTTC
+CGGCGAGGACTGTACAAGAAGGGTATAGAGCAGGTCAAAGACGAAAAGCTGCGCGGCTTT
+CGTACCGATCGAGTCACCCTGCAACATTCCTTGCCGATTACCATTGATCAGGCAAAAATC
+GGCCTCTTCACATAATGGAGAACCCAGATTATGGGTAATGGCGACTGTGGTGGCGCCAGC
+CTGTCGGGCCAATCGGAGTGAATGCACTGTTTCTGGCGATGTGCCCGAGTGACTGACACC
+CATCGCGACATCGCCTGCTTTTAATAGCGTAGCCTGCATGTACATAAAATGGTTATTGCT
+TACCGCATCGCCCCGTAAACCAATACGCATTAGCTTGTGTTTCATATCCAGCGCCGTGAT
+CCCCGATGAGCCCACACCAAAGATATAAACTGAGTGACAGTGACGTAGGGCGTCCACGAC
+ACCGAGAACCTGTTGCATATCAAGCAGATTTAGCGTTTCAGATAATACATTACTAATGGT
+GTTCTGCAATTTTAAACCAATGGCGTGGGCATCGTCGGATTCGCTAACTTCGGCATCCAG
+TAGAGGACTACTGTCATCAGACTCGGTAGTGGCAAGTTCAATGGCCAGGTCCATTTTAAA
+ATCCTGAAAACCTTTATAGCCCAGGGTGCGACAAAAGCGAATAACCGTGGCTTCTCCGGC
+CTGTGTGTCGCGCGACAAATCGGCAATAGATGACTGTGTCACCTGTCTGGGGAAGGCTAA
+AATATATTGCGCAATACGCTGGGAGGCACGTGTCAGGCTTTTTTGCATAGCACCCAGAGT
+GTCAAGGATTTTTCCGGGTTTAAGACGTGGGGGTTGAGGCTCCATATAGTTCCTGCTCTT
+GAGGGCTGATTGCGGCACAAAGCCTGCAATATCGAACAGAGCAGAGCCTATCAAGTCTGC
+GGCATGAAAAAAAGCGCGATGTAAGTAAAGGAGGGGGAATATTTACATCGCGTTGCCAAC
+TTATGACAGAACATCACTGGAGAGTAATCTGTTTGCTCTTACGGTGTTTATAGCGCGCCA
+TCTGTCGGATGGTTTATATCTGGCCCGGTATTGTCGCCCCGCGCGTTGGCGTCACCGTGT
+GCTGTGTCGGTATAGCGTGGTATCATGAAATCATAATGTCACCTTTGGTTCAGGTTTTTC
+ATCCAGCGTCAATGGCGGTGCCGGGGCAAATAACGGGGCGAAAATAACGCCGCTGATCAC
+CACGCTTAGCGAGCCAATGACCCCATAAAAGAAGAAGTTAAGGTCAGTGGCATAGCGTGT
+GCCCAGCACGGTAATGACGCTGATAATAATTCCTAAAACCGCACTCCCGGCATTTGCTCG
+TTTAAAGAAAATGCCCAGCATGAACAGACCGGTCATTGGCCCTCCCATCAGACCTATCAG
+ACTATTAAATGCATCCCAGATTTCTGATTCATCGGCCATGACCAGCCATACCGAGGCCGC
+GCTACTTATCAGGCCCGCGACCAGAATAACTAACTTAGCTATTTTCATACGGTTTTCTGG
+CGTTCCTTTTTTATGACTCAAACGCTGATAGATATCGGAATTAAAACAACTGGAAATGCT
+GTTTAAGCTGCTGGAGATGCTGGACTGCGCGGCAGCGAAAATAGCGGAGATTATCAACCC
+TGCAATGCCGACTGGCATTTCGGTGACCACGAATAAGGGCAAAATGCCGCCAGTGTTGAA
+TCCCGCCGGTAATAATTGTGGATGTTGCTGATAGTAGACAAATAATGCCGAGCCGATAGC
+AAAAAAGAAAACAGGGATCACAGCAACCAGTTTGGCATTTGTAAGTAATGTTTTCTTCGT
+TTCCTCTATGGAGTCAGTCACGATATAGCGTTGGACCACATCCTGACTGGCAGTAAATTG
+CTGAATATTGGCAAACAGAAAACCAATCATCAATACAGGTACTGTGCTTTCCGTCCAGCT
+CCAGTGGAACTGCGTAGCCGGAAAGAATTTATCCGCCTGCTGCGTCACCGTAAAAATTTC
+ACCAATGCCGCCCTGGACTTTGAGACATATCACTATAAAAATCAGTATCGCGCTGCCAGA
+AAGTAAGAGACCTTGAATAACATCAGTCCATATTACTCCTTCAATTCCCCCCCATCCAGG
+TATAAATGATACACATCACACTAATCAACAGTACCAAAATCACCGGGTCTATAGCGATGA
+AGGGGCGCAAGGCCAGCACGGTGAGGAAAGTGATAATGGCGATACGTCCAATATGAAACA
+ACATAAATGACATGCTGGCGAACAGACGGCAGCGCACATCGAACCGTGCTTCGAGATATT
+CATAGGCTGATGTGACTTTCAATTTCCGAAAAAACGGAATATAGAAATAAAAAACCAGCG
+GTAAAATTGCGATAGCCAGATACTGACCAATGATAAACGTCCAGTCGGAAGTAAACGCTT
+TGGCAGGAATTGACATAAATGTAATTGAGCTTAACGTAGTAGCAAATACACTGACCCCAG
+CCGCCCAACCAGGAACCCGGCCACCACCGCGAAAATAATCGTCTGCTGTTTTTTGCCGTC
+TGGAAAAATAGACACCGACTAACATCATGGCCAGGAGGTAGCCAAATAATACAAAATAAT
+TAACGATGCCGAAAGAATGTGTAATCATAGTTCTTTCCTGCTTATGGTTTTGAGTAGCGT
+TGCGGTCATCGTCTGTGTATTTTTATCTTCCCATCATTCAGACGATACGATATTCAGATC
+AAGCAATAGTTTTTGTTAATCTCAATGACGCTAATCATGAGATGTAAAAGGCAGAGCATT
+TATGCTCCACCAATGGTGATGCCCAGACGTATGTCCTGCCGGATACCTGAAATAGCAGCT
+ATCCGATATTGCGTTCAAACAGGCTTCAGGCCTGGGTATCGTATTTGCCGATAGCATTCT
+TAACGTCGGATTATTCTCTGAGACATAAATATCAATAGTAAGCGTGTTCATTTTCTTTTC
+CTGTTCAGCGTTTTACTGCGTGACTGAACCACTGACAGATATGCTCGATACGGGTGATAG
+CGGAACCAACGGTAACTGCCCAGGCACCATGCTCAATAGCATTGGCCGCCAGTGCAGGCG
+TGTTATAGCGCCCCTCGGCAATAACACGACAACCTGCATGACTCAGTTGTGTCACCATTG
+CCAAATCTGGCTCAACCGGCGTGATGGGACCGGTATAGCCAGACAGTGTTGTACCAATGA
+ATTCGATTCCTTTCTGATGGCAACTTATGCCTTCATTCACGGTTGAACAGTCTGCCATCG
+CCAGTAATCCATGCAGGCGAATACGTGTCAGTAAACTATCAATATCAACCGGGCGAGAGC
+GGAATGAGGCATCAAAAGCGATAATATCGGCACCTGCCTGCGCCAGGGCGTCAACATCCT
+GTAAATATGGAGTGATACGGACTGGCGACCCTGTAAGGTCACGTTTAATTATCCCAATAA
+TAGGAACAGAAAGATGGGGACGAACAGTCCGCAGATTCTCAATGCCTTCAATGCGCACAG
+CGACCGCACCCGCCGAAGCCGCTGCCTGTGCCATTGCAGCCACAATTTCAGGTTTATCCA
+TAGGGCTGCCTGGTACCGGTTGGCATGAGACAATCAGCCCACCGTTTTCGTGTACACTTT
+GTTCCAGCCTGGCTAATAGTGACATCCAGTTCCGCCTTATATATTTTGAAGTTTTACTCC
+GTTTTATATTATGTTGTGGAGTGTTGCTGCATCAAGCAAAAAGATAGAAAAATGTGAACA
+CAGTCATAAGGTATGTTTGTCATTCAATTACTGCGCCAGCGGATTTGAGGCTATAACCTG
+AAGCTACAAGACAAATACAATTCATTCTGACGGCAGCATGCTGTATTTTATTAACTGCTT
+CCGGCATAAAGATAAAATGCTCAGAAGGAGCTTATACGCCACGGGATAGCCAGTATGAAA
+TGCATCACATAATTCTTGTTGTATTTATTCAGAATGCAATCACTAATGAGTTTGCCCATA
+ACAGGTCACCCATAATCACTTCTAACATCACCATAGTGTGCTTTTACCTCGCACATGGTA
+ACCCCATGTAATTATTTTTAGCGCTTGGTCACATTTTGTCATTTTCATTGTTGAAATTAT
+GCACCATAAGATCACTAATGATGAAGCTTTACTCCAGTTGTATTTCTTCGCATGGGGATG
+CAGATGAAAAATTTTAAGAAAATGATGACGCTAATGGCGCTATGTTTATCAGTTGCTATC
+ACCACATCAGGATATGCAACCACGCTTCCTGATATACCAGAACCACTGAAAAATGGTACT
+GGCGCTATTGATAATAATGGCGTGATTTATGTCGGCTTAGGTACCGCAGGGACATCCTGG
+TATAAAATTGATCTTAAAAAGCAACATAAAGACTGGGAGCGTATAAAGTCGTTTCCTGGT
+GGAGCTCGTGAGCAATCCGTGTCGGTATTTTTAAATGATAAGCTGTATGTTTTTGGTGGC
+GTAGGGAAAAAAAACAGTGAATCACCGTTGCAGGTTTATAGCGATGTGTACAAATACTCA
+CCGGTGAAAAATACATGGCAAAAAGTTGATACTATATCTCCAGTTGGATTAACAGGGCAT
+ACGGGAGTAAAATTAAACGAAACGATGGTACTTATTACCGGAGGGGTTAATGAGCATATC
+TTTGATAAGTATTTTATTGATATAGCGGCTGCGGATGAAAGTGAAAAAAATAAAGTCATC
+TATAATTATTTTAATAAACCTGCCAAAGATTATTTTTTTAATAAAATCGTATTTATCTAC
+AATGCTAAAGAGAACACATGGAAGAATGCCGGTGAGCTGCCAGGCGCGGGGACGGCAGGA
+TCGTCATCGGTAATGGAAAATAATTTCTTGATGCTGATTAATGGTGAGCTCAAACCGGGT
+TTACGTACCGATGTGATTTACCGCGCCATGTGGGATAACGATAAGCTAACATGGTTGAAG
+AACAGCCAGTTACCGCCATCGCCTGGAGAACAACAGCAGGAAGGGTTGGCCGGAGCATTT
+TCGGGCTATAGCCACGGTGTCCTGCTTGTCGGTGGTGGCGCGAATTTTCCGGGAGCAAAA
+CAAAATTATACTAATGGAAAGTTTTATTCCCACGAAGGGATAAATAAAAAATGGCGAGAT
+GAAGTCTATGGTTTGATTAATGGCCATTGGCAATATATGGGTAAAATGAAACAACCTCTC
+GGCTATGGTGTATCAGTAAGTTATGGTGATGAAGTTTTCCTTATTGGTGGTGAAAATGCT
+AAAGGGAAACCTGTTTCGTCTGTAACCTCCTTTACCATGCGTGATGGTAATTTATTAATA
+AAATAATTTTTTAAATACAAAAATAAAGTTAATTGATAAGCGGAGTATTTTATGAAAATC
+AACAGATATCTTCTGGGTATGGTTTCGTTTATAGCATTTTCATCATATCTACAAGCGGCA
+ACCCTTGATTATCGGCATGAATATGCTGATAGAACCAGAATTAATAAAGACCGTATTGCT
+ATAATTGAAAAGCTTCCTAACGGCATTGGTTTTTATGTCGATGCCAGCGTTAAATCGGGA
+GGAGTAGATGGTGAGCAGGATAAGCATTTAAGCGATCTCGTCGCAAACGCTATAGAACTG
+GGCGTAAGTTATAATTATAAAGTTACGGACCATTTTGTTTTGCAGCCTGGATTTATATTT
+GAAAGCGGTCCAGACACTTCAATTTATAAGCCTTATTTAAGGGCGCAATATAATTTTGAT
+TCTGGTGTTTATATGGCTGGTCGTTACCGTTATGACTATGCAAGGAAGACAGCTAACTAT
+AATGATGATGAGAAAACGAATAGATTTGATACTTATATAGGTTATGTTTTTGATGAGTTG
+AAATTGGAATATAAATTTACCTGGATGGATAGCGATCAAATTAAATTTGATAACAAAAAA
+ACAAACTATGAACATAATGTGGCTTTAGCCTGGAAACTGAATAAGTCATTTACACCATAC
+GTTGAGGTCGGAAATGTAGCGGTGAGAAATAATACCGATGAGAGACAGACCCGTTATCGC
+GTTGGATTACAATACCACTTTTGAGAAAGGTTAAAGAGTTACTGTACTAATCTTTGCTTA
+GTATTCATATCGATAATCTTATAGCCCGTAGCTACGTTACAGAACGTTAGACTTTGTCTT
+GAGTATTCACGTCCTTAACGTAGCTACGAACAAGGATGATAAACAATGAATATACGCCTT
+ACATAGCTACGATCTCAGGCGGTTGTCGGAAAGTGCCGGTTGATAGTGTCTTATTCGGCA
+ATTGATATGACTTAAAAATTAATTCCGTAAGCATTTCAGACGGTAACAGCAAATAAGGGT
+TTTATTGTGATAGCAAAATTCTTCCCGTGGTATAGCGAGATAACACGTCCACAAAAAAAT
+GCTTTATTTTCAGCATGGCTGGGTTACGTTTTTGATGGCTTCGACTTTATGCTGATTTTC
+TACATTATGTATCTGATCAAGGCTGACTTAGGATTGACAGATATGGAGGGCGCATTCCTT
+GCCACAGCGGCCTTTATTGGGCGACCATTTGGCGGGGCGCTATTTGGTCTGCTGGCAGAC
+AAATTTGGCCGTAAGCCGTTAATGATGTGGTCGATAGTTGCCTATTCTGTAGGTACAGGG
+TTAAGTGGCCTGGCTTCCGGTGTAATTATGCTGACGCTTAGTCGTTTTATTGTCGGTATG
+GGGATGGCGGGGAAGTATGCTTGCGCTTCTACTTATGCCGTGGAAAGTTGGCCAAAGCAT
+TTAAAATCTAAAGCGAGCGCATTTCTGGTTTCAGGTTTCGGTATTGGTAACATCATAGCA
+GCCTATTTTATGCCGTCATTTGCCGAAGCGTATGGTTGGCGTGCTGCTTTTTTTGTCGGT
+TTGCTACCCGTTCTTTTAGTAATCTACATCCGGGCCAGGGCTCCTGAATCTAAAGAGTGG
+GAAGAAGCCAAACTCAGTGGTCTCGGAAAGCATTCACAAAGTGCCTGGTCAGTTTTCTCT
+TTGTCAATGAAAGGGCTATTTAATCGAGCTCAATTTCCACTGACATTATGTGTATTTATT
+GTTCTGTTCTCTATTTTCGGCGCAAACTGGCCGATCTTTGGTCTACTGCCTACATATTTG
+GCGGGAGAGGGCTTTGATACGGGCGTGGTCTCTAATTTAATGACGGCGGCGGCATTCGGC
+ACTGTATTGGGAAATATCGTTTGGGGTCTGTGCGCAGATAGAATTGGTTTGAAGAAAACG
+TTCAGCATTGGTCTTCTCATGTCCTTTTTATTCATTTTCCCGTTATTCAGAATTCCGCAA
+GATAATTATTTACTGCTGGGCGCATGTTTATTCGGTTTAATGGCGACTAACGTAGGTGTT
+GGCGGGCTGGTTCCCAAATTTCTCTACGACTACTTTCCTCTTGAGGTTCGTGGTTTGGGT
+ACCGGGCTTATTTATAATCTTGCTGCGACATCAGGCACATTCAATTCAATGGCGGCGACC
+TGGCTTGGAATAACAATGGGGCTAGGCGCTGCGCTAACGTTCATTGTTGCTTTCTGGACC
+GCAACAATTCTACTCATTATTGGCCTATCCATTCCGGATAGACTAAAAGCACGTCGTGAA
+AGGTTTCAGTCAACAAAAGAATTTTAATAGAGGATAAATGATGACGAAATACGGTGTTAT
+AGGTACAGGTTATTTTGGCGCTGAACTGGCGCGATTTATGTCTAAGGTTGAAGGGGCGAA
+AATCACTGCGATTTACGATCCGGTAAATGCGGCTCCGATAGCGAAAGAGCTGAACTGTGT
+CGCCACTTCAACGATGGAGGCGCTTTGTACCCATCCTGATGTGGATTGCGTAATTATTGC
+TTCACCAAATTACTTACATAAAGCGCCGGTCATTGCGGCGGCTAAAGCGGGTAAACACGT
+GTTTTGTGAAAAACCTATCGCCTTAAATTACCAGGATTGTAAGGATATGGTTGATGCCTG
+CAAAGAAGCTGGTGTTACCTTTATGGCGGGTCACGTTATGAACTTTTTTCACGGGGTTCG
+CCACGCTAAAGCGCTCATCAAAGCCGGTGAAATCGGTGAAGTTACACAAGTTCACACTAA
+ACGTAATGGTTTTGAAGACGTGCAGGATGAGATCTCATGGAAGAAGATTCGCGCAAAGTC
+AGGTGGGCATCTGTACCATCACATTCACGAGCTAGATTGTACACTGTTCATCATGGATGA
+AACCCCATCCCTGGTTTCAATGGCGGCGGGGAATGTTGCGCACAAAGGTGAAAAATTTGG
+TGATGAAGATGATGTTGTCCTAATCACCCTTGAGTTTGAAAGCGGTCGTTTCGCGACACT
+TCAGTGGGGATCATCGTTCCACTACCCTGAGCACTATGTATTAATTGAGGGCACGACAGG
+TGCAATTCTCATTGATATGCAAAACACGGCTGGTTATCTAATAAAAGCGGGCAAAAAAAC
+ACACTTTCTTGTGCATGAAAGCCAGGCGGAGGATGATGATCGTCGCAACGGTAACATATC
+CAGCGAGATGGATGGCGCAATCGCTTATGGTAAACCCGGTAAACGTACGCCGATGTGGCT
+CTCATCAATTATGAAACTGGAGATGCAGTACTTGCATGATGTGATAAACGGTCTGGAGCC
+AGGCGAGGAGTTTGCTAAATTGCTAACGGGAGAAGCGGCGACAAATGCCATTGCTACCGC
+TGATGCTGCGACGCTTTCTTCAAACGAGGGGCGCAAAGTTAAACTCACTGAAATTCTTGG
+CTAAAATTTAAAGCCGGATGGTGGTGTTATTGGCCGGTGGCGCTGCGCTTATGTAGACTG
+GATAAGGCGCCCGTGAACTGTGCCGCCATCCGGCAATGGACGGGGGCTTAATGCGAAAAA
+AAGCCCGTACATTCGTACGAGCTCTTTCTTAAATATGGCGGTGAGGGGGGGATTGACTCG
+CTGCGCTCGCCCTTCGGGCAGCCCGTTCGCTGCGCGCCCGGTCTGTCCAACTGGCTGCGC
+CAGTTGTCGAACCCCGGTCGGTGGTTCTCATCCCCCCTTGGTTTGGGGGATACATATAAG
+CAAAAAGCCTGTACTTCTGTACAGGCTCTCAACTTGAAGATGGCGGTGAGGGGGGGATTC
+GAACCCCCGATACGTTGCCGTATACACACTTTCCAGGCGTGCTCCTTCAGCCACTCGGAC
+ACCTCACCAAATTGTCGCTCCAGCATTACTGGAACGGGCGCTAATGTAGGGAAATATCCT
+TTCTACGTCAATCAACTTTTTTAAAAAAAAGCGCTTTTATACAAACTTCCATCAATCTGT
+GGCTTTAATAAGCGAAAACTGCTTTTTTTGCCCGCGCCGGGAAATTTGCTATGCTGCACA
+TCCCGTTGAAAACGCTGATAACAGGCGCAATCACATTCCGCACAATACTGCTCAGGAGAT
+AACATGGAGATAATTTTTTATCACCCGACATTTAACGCCGCCTGGTGGGTAAATGCGCTG
+GAGAAGGCTCTCCCACATGCGCGCGTTCGTGAATGGAAGGTCGGTGATAACAACCCCGCA
+GACTATGCGCTTGTATGGCAGCCCCCGGTTGAAATGCTGGCCGGAAGACGCTTAAAAGCC
+GTCTTTGTGCTGGGCGCGGGGGTGGATGCAATTCTGAGTAAATTAAATGCGCATCCGGAA
+ATGCTGGACGCCTCCATTCCTCTATTCCGTCTGGAAGATACCGGAATGGGCCTGCAAATG
+CAGGAGTATGCCGCCAGCCAGGTATTACACTGGTTCCGTCGTTTCGATGATTATCAGGCG
+CTGAAAAATCAGGCGCTATGGAAACCGTTGCCGGAATATACCCGCGAAGAGTTTAGCGTC
+GGTATCATAGGCGCAGGGGTACTGGGCGCAAAAGTGGCAGAAAGTCTACAGGCGTGGGGG
+TTCCCGTTACGTTGCTGGAGTCGTAGCCGCAAATCCTGGCCTGGCGTGGAAAGTTATGTA
+GGGCGTGAAGAACTGCGCGCTTTCCTGAACCAGACGCGGGTGCTGATTAATCTGCTGCCG
+AATACGGCCCAAACGGTAGGAATTATTAATAGCGAATTGTTGGATCAATTGCCGGATGGC
+GCTTACGTGCTGAATCTCGCGCGCGGCGTTCATGTTCAGGAGGCGGATCTGCTGGCTGCG
+CTTGATAGCGGTAAGCTAAAAGGCGCGATGTTGGATGTCTTTAGCCAGGAACCGTTACCG
+CAGGAAAGTCCATTATGGCGCCATCCGCGAGTCGCCATGACGCCGCACATTGCGGCAGTC
+ACCCGTCCGGCGGAAGCCATCGATTATATTAGCCGCACCATTACCCAGCTGGAGAAGGGA
+GAGCCGGTGACGGGGCAGGTGGATCGGGCGAGAGGATATTGATATCAACCCGGCGCGGGC
+CGGGTTTCGCTAAAAAACGCTGGCGATACCTGCTATCCTTGTCGGAAATGACTACAGGAG
+AGAGCAATGTATCCCGTTGACCTGCATATGCATACCGTCGCCAGCACTCATGCCTACAGT
+ACTCTGAGCGATTATATCGCGGAAGCCAAACGCAAAGGCATTAAACTTTTTGCGATTACC
+GATCATGGTCCGGACATGGAAGATGCGCCGCATCACTGGCATTTTATTAACATGCGCATC
+TGGCCGCGTCTGGTTGACGGCGTGGGGATACTGCGTGGCATTGAGGCGAATATCAAGAAT
+ATTAACGGTGAAATTGATTGTTCCGGAAAGATGTTCGACTCGCTGGATCTGATTATCGCA
+GGCTTTCATGAGCCCGTTTTTGCGCCGCATGATAAAGAAACCAATACTCAGGCGATGATC
+GCGACCATCGCCAGCGGCAAGGTGCATATAATTAGTCACCCCGGAAATCCAAAGTATCCA
+GTGGAGGTTAAAGCCATCGCGCAGGCGGCGGCGAAACACCATGTAGCGCTGGAAATCAAC
+AACTCTTCTTTTCTGCATTCGCGTAAAGGAAGCGAAGATAATTGCCGCGCGGTCGCTGCC
+GCCGTACGCGATGCGGGAGGCTGGGTAGCGTTAGGCTCTGATTCCCATACGGCCTTTACG
+CTTGGCGATTTCACCGAATGCCGGAAAATTCTGGATGCGGTGAATTTTCCGGAAGATCGA
+ATCCTGAACGTCTCTCCGCAGCGCTTACTGGCCTTTCTCGAATCACGCGGTATGGCGCCT
+GTACCGGAATTTGCCGAACTTTAATCGTTATTTACGGGAAGATATCAATGAATGAGTTTT
+CAATCCTGTGCCGTGTGCTGGGATCGTTGTTTTACCGCCAACCGCAAGATCCTTTACTGG
+TTCCGCTGTTTACGTTAATCCGTGAAGGTAAACTGGCGGCAAACTGGCCGCTGGAGCAGG
+ATGACATGCTGGCGCGTTTACAGAAAAGCTGCGATATCACGCAGATTTCCACTGATTACA
+ATGCGTTATTTGTTGGGGAAGAGTGCGCGGTAGCGCCATACCGCAGTGCGTGGGTCGAAG
+GCGCGGAAGAGTCTGAGGTGCGCGCTTTTTTAACGTCGCGAGGGATGCCGCTGGCCGATA
+CGCCTGCCGATCACATTGGCACTTTATTGCTCGCGGCCTCCTGGCTGGAAGATCAGTCTG
+CCGAAGATGAAAGTGAAGCGCTGGAAACCTTATTTGCCGATTATCTGCTTCCCTGGTGCA
+ATACCTTCCTCGGTAAAGTTGAAGCCCATGCCGTTACGCCATTCTGGCGCACTCTGGCGC
+CGCTAACGCGTGATGCGATAGGGGCCATGTGGGATGAACTTCAGGAAGAAGATGAAGAAT
+AATGTGATGTAAATCACCATTAACTGCAACGGGTTTTGCATCATTGCATAAAATGTGTGC
+GTGATCTCATTAATGTGCCGCTTTTCTGTTATGATGCGCGCCATGAACATACTTCTTTCT
+ATTGCTATCACTACGGGCATCCTTTCTGGAATATGGGGATGGGTGGCCGTCTCCCTGGGG
+TTACTAAGCTGGGCCGGTTTTTTAGGCTGTACGGCTTATTTCGCCTGTCCGCAGGGCGGC
+TTTAAGGGATTGTTGATTTCCGCCTGTACGCTGTTAAGCGGTATGGTGTGGGCGCTGGTC
+ATTATTCACGGTAGCGCGTTGGCGCCGCATCTGGAAATTGTCAGTTACGTGTTGACGGGG
+ATCGTGGCATTCCTGATGTGTATCCAGGCAAAGCAGCTATTGCTTTCTTTTGTTCCGGGA
+ACATTTATCGGCGCCTGCGCGACATTTGCAGGGCAGGGTGACTGGCGGTTGGTATTACCG
+TCGCTGGCGCTGGGGCTAATCTTTGGCTATGCCATGAAAAATAGTGGGCTATGGCTGGCA
+TCACGCCGCGAGCAACATTCAGCGAATACGGCGGTCACAAAATAAAAAAGCGTGGGGTTT
+TCCCCACGCTTTGTCGTATTCATCAGGATTCTGGCGGTACTGACAGCTCACGGTATTTCA
+CCAGAATATCATTTTGCCTGTCCGCTTTATTCTGCAAATCCCACAGTCCGCGATCGATAC
+CATCATTAATGAGGAAGATAACGCCGGTTTCAATGGCTGACATCAGACACAGCATCACCG
+GTTCGTTCGAGGTATAGCCGATTTCGCCTTCCAGTAAGCGCTGGTAATCAATAAAACGGA
+ACACGCCTGCCTGTACTTCATAGGAAAGGATCGTTTTACTGGTGTTCACCGAAGAAAGGA
+TCTCGCCCGTACTGACGTTAACCACGCGCAGGTTGACAGCAATCTGATCCAGCTGATACT
+GCGTATCGGCGCCAATACCGAAATATCTTGCGCCGACCCCGCCGGATTTGACGTTACTTT
+CATAACCAATAATAGAACCTTCCACCATAATATTTGCCGCCGTCAACGACTGAAGCGGGA
+TACGGTTATTCATCGCCACGGTGCCGTTTTCCTGGGCTGCGCGAATAATTTTCCGTTCAT
+TCAAAAGATTCTGTAAGCCTTGTCGTTCTAGTGGGATAAACCAGCGCGAATCTTTCAGCG
+CGGTGACCAACATAGCGGTGGCGCTCTGCGGCACAGCCGTGGAAAAGTTACTTGCCGGGT
+AAGGTTTAAATTGGCCCGTTTCATCCTGAATGTTATATACCGAAACAAAGATCTTACCGG
+TGGGAGCAGGTAAGTGCGTCAAATCTTTGTAACTTTGTGCGCGGGGCATTAATGTCGGTT
+TCGCAGCTTGTTTCGGCGGGGCAGTTAAGCATCCGCTCAACAATAAAACGGCAACCAAAA
+TAAGTAAGCGCGGCATGATTTATATCCTTTAGTGACTGTAGCTTAAAAATCGGTTGACTG
+AGTTTGTAAACCTGACACTTCGATGGTCGAGGTTCTTCCCGTTTTTCTGTCCGTGACGTT
+GAGCTGGAGCTGTCCGTCGCGATTAGCGATATCGATAATAAAATCATTGGTCACCATACG
+TCCTGGTTTTCCGGTATTAATATTGGTCAACAAGCCGCCCAGAATTTGCGATTGAATAGC
+CTGCGTAAAGTTATCCAACGCTGAGGGGGTCTCGATACCAAAATCGTTATCATAAGCGGG
+GTCTTTATATGAATTTTGCGCCTGGGCGCTATTCAATAAAAAGGAACCGTTATTGGGGTT
+TCCACCAAAGTTAGGATTACGGAACTGGAACGTCATATTTCCAGCCCAGGTTAATGGCGA
+AAAAAGCATGAGCAGCACTACTGCATGTTTAACACGCATGACAGCCTCCGGATAAAAATC
+ATGTTTTAGAATTCATCACGCGCTAAATCACTCGTACTTAATAGCGTTTGATCTATTTGT
+CGGCGATTTAATGCTTCCTCTGTTTGCGCTAATGCGAAGACGACGGTTTTCTCGAAGTCT
+CTTTTCATTGGAAATAAAAAGGTCTGGAAAATAACGTCCTGATTTACCGTTATGGTGATC
+CAGCTTCCCCAACGCGCACTGGGTCTTTCATTAATGGTCAGATTGCCGGTGTATTCGCTT
+TCCCATTTGTCGCTGAATGCACGATAGAATTCATGTCCTATCGAAGAGACGGTATGGTCG
+GTTAACAATCCGGGAACCTCGACTTCAACTTCATTGGCATGCAGGTTTCCGGTAGCGAAC
+AGTAACTCTGCTGCTACAATCCAGGTCAGATAGCGTTTCATGGCCTTACCGCCTGAGATT
+ATCGTTTGCTCATGAAACTGCCTGGGTGCGATTTTTGACAGCTATCTTTTTGAAAAGATT
+ATAAAGATGTGTCTTAACCGTATTCTCGCTGATAAATAGCGACCTGGCGATTTCATTATT
+AGAGGCACCAATACGTAACTTATTGAGGATCTCTTTTTCGCGATGAGTGAGTAATGCGGA
+CTCGGTGCTGTTGTAGCGGTAATTTCCTGAGTGTGTAATCAGGTAACTGGCTAATTTTTG
+TGAAAAATAGCATTCGCCCCGCAGAATACCCTGTAATCCGCTGACCACGTGTTCCTGGTC
+TTCAGTGGCGTAAAACACGCCGTTAATATGAGGCCAGTTTTCAATTTCACGGTAGGGATA
+ATCGTCAGGGGTATTTAACAATAATGTTTTTATATTATTGTTTTTGCGGCTTAAATTATC
+CTGCCAATAGTGGATAAGCTTCTTATCCGCTTCCATCATATCCATTAAAACAATGCAACC
+GGCTGAGATATCTTCCAGAGAACGTTGAATATTATGCAGTTTTCCGGTTATGGCCAGCGA
+TTGCTTTAAATGTTGCAATAATGCCGTAGCTTGCAGAGATGGCTTTGTGATCAACAATAG
+TGTGTGACCATGACTACTATGGACTTCATTAAACATGATGAAACTCCACTTTTTTTAATC
+GCACATCTGACAGCTGCCCCCATAAAATAAAGGCACCAGAAGTACTGACAGATGTTGCAC
+TGCTGTGGGTTGAAATAGCCCATTATCCAGAAAGAGAAAAATATTTACGAAAATACTTTT
+AACTGTTTTCAATCTAGCCATTACAAATCTTAAAGCAAGTGTTAAACTTGTAACAAGATG
+TAAAAATATATATTAAAATGTTGTTTTTGGGTTTTTTTGAAGTTTAGATTTGATAGTAAA
+GTTGTACATTTCGCTGTTATTGCATAGATTTAAAAAATCATACAAATTATAATAATTCAT
+TGATTTTTAATCATTTTAATTATTGTATGTCATGTTTTGATTTTATTTTTTCTTAAAATT
+TGAGACGTGGCATTAACCTGGACAGCACAAAGACAAAAAAAAACGAAGTGTGTCACGTCT
+TGTGCGTATTGCCCCCCATGGGAAGCATAAGAACATCCCCATGGCGGCATAACACACACC
+AACACTTCATTTTTTAGGTGCGCGATACACTATCTTCTGTGGCCAAAAATCAATTATAAA
+AAATCACATGGCTATCGTTTTATTAGCACTTTGGTATGAGCTTAAATAACAAAATACCAC
+GCGTGGGTGAGTTATTAAAAATGTTTCCACGGACATACTCTTCATCGTAACGACGCGTTA
+ACAAAAAACGCATGTCGCTAACAAGGTAATAGATAATTTTCGCTATGTACGACCAGGTCC
+AGGGTGACAGCATGAAAAACAAATTGTTATTTATGATGTTGACAATACTGGGTGCGCCTG
+GGATTGCAACCGCGACAAATTATGATCTGGCTCGTTCAGAGTATAATTTTGCGGTAAATG
+AATTAAGCAAGTCTTCATTTAATCAGGCGGCCATTATTGGTCAAGTCGGCACGGATAATA
+GTGCCAGAGTACGCCAGGAAGGATCAAAACTATTGTCCGTTATTTCACAAGAAGGAGAAA
+ATAATCGGGCGAAAGTCGACCAGGCAGGGAATTATAACTTTGCGTATATTGAGCAAACGG
+GCAATGCCAACGATGCCAGTATATCGCAAAGCGCTTACGGTAATAGTGCGGCTATTATCC
+AGAAAGGTTCTGGAAATAAGGCCAATATTACCCAGTACGGTACGCAGAAAACAGCAGTTG
+TAGTGCAGAAACAGTCGCATATGGCTATTCGCGTCACCCAACGCTAATACCGTTACGACT
+TTTAAATCAATCCGATGGGGGTTTTACCATGAAACTTTTAAAAGTGGCAGCATTCGCAGC
+AATCGTAGTTTCTGGCAGTGCTCTGGCTGGCGTCGTTCCACAATGGGGCGGCGGCGGTAA
+TCATAACGGCGGCGGCAATAGTTCCGGGCCGGATTCCACGTTGAGCATTTATCAGTACGG
+TTCCGCTAACGCTGCGCTTGCTCTGCAAAGCGATGCCCGTAAATCTGAAACGACCATTAC
+CCAGAGCGGTTATGGTAACGGCGCCGATGTAGGCCAGGGTGCGGATAACAGTACTATTGA
+ACTGACTCAGAATGGTTTCAGAAACAATGCCACCATCGACCAGTGGAACGCTAAAAACTC
+CGATATTACTGTCGGTCAATACGGCGGTAATAACGCCGCGCTGGTTAATCAGACCGCATC
+TGATTCCAGCGTAATGGTGCGTCAGGTTGGTTTTGGCAACAACGCCACGGCTAACCAGTA
+TTAATTTAGCGTCTGCGCTAATAAAAAAACAGGGCGTAAGCCCTGTTTTTTTTCGGGAGG
+AAATTATGCATACTTTATTGCTCCTTGCCGCACTTTCAAATCAGATTACGTTTACCACGA
+CTCAGCAAGGCGATATTTACACGGTGATCCCTCAGGTCACATTAAACGAACCCTGCGTCT
+GTCTGGTGCAAATTCTCTCTGTGCGCGACGGCGTCGGGGGACAAAGCCATACACAGCAAA
+AACAAACGCTATCTTTACCTGCTAATCAACCGATTGAGTTGTCTCGTCTTAGTGTAAATA
+TATCTTCAGAGGACTCGGTTAAAATTATTGTTACTGTTTCGGACGGACAATCACTGCATT
+TATCACAACAATGGCCGCCTTCTGCACAGTAGTTTTTGATGGTGGCGGAAATGGATTGGC
+TGACCTGGGTATTAAAGAGGCGATAAAAGCGTCTCATCGTCTCGGCATGTCGCTAAAAGG
+TAACGCCGAACCCTCGAGGATGACTAATCATTGAGGAGTTAACATGTCCGTAATCAAGAA
+AAATATCCCTGCCATAGGCCTGTGTATCTGCGCTTTTTTTATCCATTCTGCGGTAGGGCA
+ACAAACGGTACAGGGCGGCGTTATCCATTTTCGCGGCGCGATTGTTGAGCCACTGTGCGA
+TATTTCTACTCACGCCGAAAATATTGATTTAACCTGCCTACGCGAAGGTAAAAAGCAAAT
+GCACCGGATAGACCTTCGGCAGGCATCTGGATTACCGCAGGATATTCAGTCCATTGCGAC
+GGTACGGCTGCATTATCTCGATGCGCAAAAAAGCCTGGCGGTGATGAATATTGAGTACCG
+TTAACGGCGGTGTCATAGATATAAAAAGAGCGACTCTGTTGAAAGCCCTGCTGTACACTT
+TGCAGATAAGGTGAGACAAAAGGGGGGGGTTATGACATCACGTCTTCAGGTCATACAGGG
+TGATATCACTCAACTTAGCGTCGATGCGATTGTGAATGCCGCTAACGCATCATTAATGGG
+CGGCGGTGGCGTAGACGGCGCAATTCATCGCGCGGCGGGGCCGGCATTGCTGGACGCCTG
+TAAACTCATCCGTCAGCAACAGGGCGAATGTCAGACGGGACATGCGGTTATCACGCCTGC
+TGGCAAGCTTTCGGCAAAGGCGGTTATTCACACAGTGGGGCCCGTCTGGCGAGGCGGCGA
+ACACCAGGAAGCTGAGCTACTCGAAGAGGCATACCGGAATTGTTTGCTGCTTGCCGAGGC
+GAATCACTTTCGTTCCATCGCTTTTCCGGCAATCAGTACCGGCGTTTATGGCTATCCACG
+CGCCCAGGCCGCTGAAGTCGCCGTCAGGACGGTTTCAGATTTTATTACCCGTTACGCTCT
+GCCTGAACAGGTATACTTTGTCTGTTATGATGAAGAAACTGCCCGGCTTTACGCAAGATT
+ACTTACTCAGCAAGGCGACGACCCTGCCTGATAAAACACGCCTGGAGCGTGCCGTTGAAC
+CGCTATGCGCGCGCCATCCCGGAGAGTGCGGCATTCTTGCGCTGGATAACAGTCTGGACG
+CTTTTGCCGCCCGCTACCGCCTGACCGAAATGGCGGCGCGGACGCTGGATGTGCAGTATT
+ATATTTGGGAAGACGATATGTCCGGGCGGCTGCTCTTTTCGGTTCTGCTGTCGGCGGCGA
+AGCGCGGCGTTCATGTTCGTCTGCTGCTGGATGATAACAATACGCCTGGTCTGGATGATA
+CGTTGCGCTTGCTGGATAGCCATCCTAATATCGAAGTTCGTCTGTTTAATCCTTTCTCTT
+TTCGTACGCTACGCGCGCTGGGATATTTGACGGATTTTGCGCGGCTGAATCGGCGGATGC
+ACAATAAAAGTTACACTGCCGACGGCGTAGTGACGCTGGTCGGTGGGCGCAACATCGGCG
+ATGCCTATTTCGGCGCTGGCGAGGAGCCGCTATTTTCCGATCTGGACGTGATGGCCATTG
+GCCCGGTGGTCAATGATGTCGCCAATGATTTTGAACGTTACTGGCGCTGTAGTTCAGTGT
+CGACATTGCAGCAAGTATTATCCCTTTCTGAGCAGGAACTGACGCAGCGTATCGAACTTC
+CCGAATCCTGGTATAACGATGAGATCACCCGCCGTTATCTGCATAAGCTGGAAACCAGCC
+AGTTTATGGCGGATCTCGATCGCGGAACGTTGCCGCTGATTTGGGCAAAAACACGCTTGC
+TTAGCGATGACCCTTCTAAAGGCGAGGGGAAGGCGCAGCGCCATTCGCTTCTTCCGCAGC
+GATTATTTGACGTGATGGGGTCGCCGACGGAGCGTATCGACATTATTTCCGCTTACTTTG
+TCCCTACGCGCGCAGGCGTGGCGCAGTTGCTTAATCTGGTCAGGAAAGGTGTGAAGATCG
+CCATCTTAACTAACTCTCTGGCGGCCAACGATGTGGCGGTCGTTCACGCAGGGTACGCGC
+GCTGGCGCAAGAAATTACTGCGCTATGGCGTGGAGCTCTACGAACTGAAACCGACCCGCG
+AACATGAAACCGCCGTACATGATCGCGGACTCACCGGGAACTCAGGTTCCAGCTTACATG
+CTAAAACGTTCAGTATTGATGGTAGTAAGGTGTTTATCGGGTCGCTTAATTTTGATCCCC
+GTTCAACGCTTTTAAATACCGAAATGGGCTTTGTCATTGAAAGTGAAACGCTGGCGACGC
+TTATTCATAAGCGTTTTACGCAGAGCCAACGCGATGCGGCCTGGCAACTGCGGCTGGATC
+GCTGGGGACGAATTAACTGGATCGATCGTCAGCAAGAAGAGGAAAAGGTGTTAAAGAAAG
+AACCCGCTACGCGTTTCTGGCAGCGAGTTCTGGTACGGTTGGCGGCAATTTTACCTGTGG
+AATGGTTGCTGTGAACCCGCGCGCGGAAAACTACCCGATCGCGGCGCGGCTTTCTTGTTT
+TACCGGCGGTTTACCTGAAAAGAGAAATTTCAGGAGCGGGATGCGTAAATGAATTTCATA
+CAGAATTAACGCAATACCCATAACAAATATCAGCCCGCACAAGAACCCGATCAGGTTGGA
+GGAGATATGCGGTGTAATATACGCGCCAAAGAAAAGCGTTAAGGGATGATGCACCAGATA
+AATAAACAGCGAAGCATTCACGAAATAGGTGACACGCGCGGACTGAAAGTTTAACAAGCG
+ATGCCCCAGTGAAAATACCACGTTCACCATCCATAGCCCCATTACCATCGTAATCACGGA
+TTCGGTTTCGTACATCCAGGCGTCGCCGCTCCCATAACGTTGATTCAGCAGATACGCGAT
+AAAAGCAACGGCAGCGCCTAAAGTGCATCCGCGTGAGGGCGTGGTGAAGCGCGCTTTCAG
+ATCGGGGTGAATGAAGGCCAACGCGCCGAGAATAAAAAACGGCACATAAAATAGCGTTTG
+CATCACAATAAAATTGAACATGCCGTCACTGAGGATTGCCGGATATACGATGAATATAAT
+GCGCCTGATAGCAGCGTACGCCACCCCCAGCAGGAAAAAAATAAGCGAAAGTTTGGCCAG
+CGAAATAGCGGCGGGACGAGGCTTGCTTGTTTCCTGCCTTTTTTGGAACCAGGTAAAAAT
+CCCGATGCTGACGGTGGTTAATATCACCAGCACCAGTAAAAACCACAGATGTGAAATGAG
+TTCCCACGCTAACGTATTATATTTTTCATAGGCAGAGAGTGTAGGCCAGTTCTCTGTTTT
+CTCTTTGACATATTGCAACAGGATAAATTGCGGCAAGGTAAGCAAAGGGATTGCGGTAAG
+CATGGGAATACCCACACGTTCTACCCGTACTTTCCACCAGTGTTTTAATGGATAACGTAA
+AAATAACATGTACGAAAAATAACCAGAAATAACAAAAAACACCTGCATACGAAAAGCGTG
+GATAAAATCGTTAAACAGGGTTAGCCACCACGATGGCGCGGCGCTATTGACATGCCAACT
+GTGAGTGGAATAGATCAACGAGATATGAAAGGGAATCCCTAACAACATCAGCCATGCGCG
+GATAGAGTCAAGAAAATATTCACGCGGCGCGGGTACAGAGCTCATATAAGGTCACGTATT
+CTCAGATTTTTCACCTTATCCATAAGGCGAATTATAGTTACATTCGGTAGCAACCCTACA
+CCAACTCCGACAACCTGTCTCCAGGATAAGCACGCAAAGTGAAAACAGGCGCGGGAGGTG
+CTTAATCCATGAGCCAGCGCGCTGAACAAAGCCTGGATTCAGTTGTCGTAATGCCTGATT
+ATCCATTAAAATGGATCGGATCGATATAAGCACACAAAGGGGGAAGTGCTTACTTATTAT
+GAAACATAAACGACAAATGATGAAAATGCGTTGGTTGGGCGCAGCTATTATGTTAACGCT
+CTACGCATCATCGAGCTGGGCGTTCAGTATTGATGACGTGGCAAAACAAGCTCAATCTTT
+AGCCGGGAAAGGCTATGAGGCGCCTAAAAGCAACTTGCCCTCCGTTTTCCGCGACATGAA
+ATATGCGGATTATCAGCAGATCCAGTTTAACAGCGATAAAGCCTACTGGAACAACTTAAA
+GACCCCTTTTAAGCTCGAATTTTACCATCAGGGGATGTACTTCGATACGCCGGTCAAGAT
+TAACGAAGTGACGGCGACGACGGTCAAAAGAATCAAATACAGCCCGGATTACTTCAATTT
+TGGCAATGTTCAGCACGATAAAGACACGGTAAAAGATTTAGGCTTCGCCGGGTTCAAAGT
+CCTGTACCCCATTAACAGTAAAGATAAGAACGACGAAATCGTCAGTATGCTTGGCGCCAG
+CTATTTCCGCGTTATCGGCGCAGGCCAGGTGTATGGCTTATCTGCGCGCGGCCTGGCGAT
+TGATACCGCCTTACCATCTGGTGAAGAGTTTCCCCGCTTTCGCGAGTTCTGGATTGAGCG
+TCCAAAACCCACCGATAAGCGTTTGACCGTCTATGCATTACTGGATTCTCCGCGCGCGAC
+CGGCGCTTACCGTTTTGTGATCATTCCTGGCCGCGATACCGTGGTGGACGTGCAGTCAAA
+AGTCTATCTGCGCGATAAGGTGGGCAAGCTGGGCGTTGCGCCATTAACCAGTATGTTCCT
+GTTTGGGCCAAACCAGCCGTCGCCGACGACCAACTATCGTCCGGAATTGCATGACTCGAA
+CGGCTTATCCATTCATGCGGGTAATGGCGAGTGGATTTGGCGTCCGCTGAACAATCCAAA
+ACACCTCGCTGTGAGCAGCTATGCGATGGAAAACCCTCAGGGATTCGGCCTGTTGCAGCG
+TGGTCGCGAGTTCTCGCGCTTTGAAGATTTAGACGATCGCTATGACCTGCGTCCAAGCGC
+CTGGATTACCCCGAAAGGCGACTGGGGCAAAGGTAAGGTTGAACTGGTTGAAATTCCGAC
+CAATGATGAAACCAACGATAACATCGTCGCTTACTGGACTCCGGATCAACTGCCGGAACC
+GGGTAAAGAGATGAACTTCAAGTACACTCTGACCTTCAGCCGCGATGAAGATAAACTTCA
+TGCGCCGGATAATGCCTGGGTGCTGCAAACACGCCGCTCAACGGGCGACGTTAAACAGTC
+GAATCTGATTCGCCAGCCCGACGGCACTATTGCCTTTGTGGTGGATTTCGTTGGCGCCGA
+CATGAAAAAACTGCCGCCGGATACGCCCGTCGCTGCACAAACCAGCATTGGCGATAACGG
+TGAAATCGTTGACAGTAATGTACGCTATAACCCAGTCACTAAAGGCTGGCGTTTAATGCT
+GCGCGTGAAAGTCAAAGACGCGAAGAAAACCACGGAAATGCGTGCCGCATTGGTGAATGC
+CGATCAGACGCTAAGTGAAACCTGGAGCTACCAGTTACCTGCCAATGAATAAAACAACTG
+AGTATATTGACGCACTGCTGCTTTCTGAACGTGAGAAAGCGGCATTGCCGAAAACTGACA
+TCCGCGCCGTGCATCAGGCGCTGGATGCCGAGCATCGGACTTACTCGCGAGAAGACGATT
+CACCGCAGGGTTCCGTAAAAGCCCGCCTTGAACACGCCTGGCCGGATTCATTGGCGAAGG
+GGCAGTTAATTAAAGATGATGAAGGGCGCGATCAGTTGCAGGCTATGCCAAAAGCGACGC
+GCTCTTCGATGTTTCCTGATCCCTGGCGAACCAACCCGGTTGGCCGTTTCTGGGATCGCC
+TGCGTGGGCGGGATGTAACGCCGCGCTATGTTTCTCGTCTGACAAAAGAAGAGCAGGCGA
+GTGAGCAAAAATGGCGTACCGTCGGCACTATACGCCGCTATATTTTGTTAATTTTGACTC
+TGGCGCAAACCGTCGTCGCGACCTGGTATATGAAGACCATTCTGCCCTATCAGGGATGGG
+CGCTCATCAATCCTATGGATATGGTGGGGCAGGATATTTGGGTCTCCTTTATGCAGCTCC
+TGCCCTACATGCTGCAAACCGGTATCCTGATTTTGTTTGCCGTGCTGTTCTGCTGGGTGT
+CTGCCGGATTCTGGACGGCGCTGATGGGCTTCCTGCAACTGCTTATCGGGCGCGATAAGT
+ACAGTATCTCCGCGTCTACGGTTGGCGATGAGCCCCTCAATCCGGAACACCAGACGGCGC
+TGATCATGCCTATCTGTAATGAAGACGTTAGCCGCGTTTTCGCCGGTCTGCGCGCGACCT
+GGGAGTCCGTTAAAGCCACAGGCAACGCCGCGCATTTTGACGTCTATATCCTTAGCGATA
+GTTATAACCCGGATATCTGCGTGGCGGAGCAAAAGGCGTGGATGGAGCTCATCGCGGAAG
+TGCAGGGCGAAGGCCAAATTTTTTACCGTCGCCGCCGCCGCCGTATGAAACGCAAAAGCG
+GCAATATTGACGATTTTTGCCGCCGCTGGGGCAATCAGTACAGCTATATGGTGGTGCTGG
+ACGCGGACTCAGTGATGAGCGGCGAGTGTCTGAGCGGGCTGGTGCGCCTGATGGAAGCGA
+ACCCTAACGCCGGGATTATCCAGTCTTCGCCGAAAGCGTCGGGGATGGATACTCTGTATG
+CCCGCTGCCAACAGTTCGCGACCCGTGTTTATGGACCGCTGTTTACCGCCGGGCTGCACT
+TCTGGCAGTTGGGGGAGTCGCACTACTGGGGGCACAATGCCATTATCCGCGTGAAGCCGT
+TTATCGAGCACTGCGCTCTGGCGCCGCTGCCGGGAGAAGGTTCGTTCGCCGGATCGATTC
+TTTCCCACGACTTTGTGGAGGCGGCGCTAATGCGTCGGGCAGGGTGGGGCGTCTGGATTG
+CCTACGATCTCCCCGGCTCCTATGAAGAGCTGCCGCCAAACCTGCTGGATGAGCTTAAAC
+GCGACCGCCGCTGGTGTCACGGCAACCTGATGAACTTTCGTCTGTTCCTGGTGAAAGGAA
+TGCACCCGGTGCATCGCGCCGTGTTCCTGACCGGGGTAATGTCATACCTGTCCGCGCCGT
+TATGGTTTATGTTCCTCGCGCTTTCTACCGCGCTGCAGGTCGTTCATGCGTTAACAGAGC
+CGCAATATTTCCTTCAGCCGCGCCAGCTTTTTCCGGTCTGGCCGCAGTGGCGTCCGGAAC
+TGGCAATCGCGCTGTTTGCGTCAACGATGGTGCTGCTGTTCCTGCCGAAGCTGCTCAGTA
+TTATGCTGATCTGGTGTAAAGGCACCAAAGAGTATGGCGGTTTCTGGCGCGTTACGCTGT
+CGCTATTGCTGGAAGTGCTGTTCTCCGTGTTGCTGGCGCCGGTGCGTATGCTGTTTCATA
+CCGTGTTTGTGGTCAGCGCGTTCCTCGGCTGGGAAGTGGTCTGGAACTCACCGCAACGCG
+ACGATGATTCTACGCCGTGGGGAGAAGCCTTTATGCGTCACGGCTCTCAACTGCTGCTGG
+GGCTGGTCTGGGCGGTGGGTATGGCGTGGCTGGATTTACGCTTTCTGTTCTGGCTGGCGC
+CGATTGTCTTTTCGCTGATTCTGTCGCCATTTGTTTCGGTGATCTCCAGTCGTTCAACGG
+TAGGATTACGCACCAAACGCTGGAAGCTGTTCCTGATCCCGGAAGAGTATTCGCCGCCTC
+AGGTGTTGGTCGATACCGATAAATATCTGGAGATGAATCGCCGCCGTATTCTGGACGATG
+GCTTTATGCATGCGGTATTTAACCCGTCGCTTAATGCGCTGGCGACCGCGATGGCCACCG
+CGCGTCACCGCGCCAGTAAGGTGCTGGAAATAGCCCGCGATCGTCATGTGGAGCAGGCGC
+TAAACGAAACGCCGGAGAAACTGAACCGCGATCGGCGTCTGGTTTTGCTCAGCGATCCGG
+TGACGATGGCGCGTTTACACTATCGGGTCTGGAATGCGCCAGAGAGATACTCTTCCTGGG
+TAAACCATTATCAGTCTCTCGTCCTGAATCCGCAGGCGTTGCAGGGACGAACATCGTCAG
+CGGGATAAGGTCTTCAGGTCTGGAGTGAGGTGAAAAATACCGGCGTGATGCCGGTATTTT
+TATAGTGAAATGAGGTATCAGGTGCGTATATTCGCGGTGAGCATAATGGTGATTACCCTG
+AGCGGCTGCGGCAGTATTATCAGCAGAACGATCCCCGGACAAGGACACGGCAACCAGTAT
+TACCCTGGCGTGCAGTGGGATATGCGTGATTCCGCATGGCGCTATATCACTATCCTCGAT
+CTGCCCTTCTCACTGATCTTCGATACACTGCTACTGCCGCTCGATATTCACCACGGGCCT
+TATGAGTAATTAACGCTCATCCCATTCGTCTGCCGCAGTACGGCCTTCCTCGGTATCAAG
+CGGGGGTTCAAGCTGGAATTCCCCTTCATCCCATTCATGCAAAGTATTCTCTTCCTGCCA
+TTCCTGGCGGATCTCTATCTCATCATAATCGCCGTCAAACACGCTCTGTGCGGCTTCACC
+ACTCAGCATCGGCAGACATTCGCCATCTTCACCTTCATCGGCGAAAAATTCGACCTGCCA
+CATGATGTCCCCATCCTGCAGTACATATTTCTGAACGTTGAACTGCTGCACATTCGCTTC
+GTCTTGTTCGAGGCCTGGATGGTCAGCCAGAAATTCTTCCCGGGCTGCATCGATAGCTTC
+TTCCAGCGTGGCATACATGGTCATCAGTGTCTCCCTTTGATTTGACGAGGTATTTAGGGA
+AAGAATAGCTGATTCTGTGATATTGCAAGTATGAAAGCGCAAAAATCATTCTATTGCCAG
+TCTGCGCCGTCGTAAGCTGTTCCATGAATAGATAGCATTGAACAACACCACGCCTGCCGT
+GACGCAGAATACGGCGCGGAAGCCATAGCTCGCGGAAATTGCGGCACCCATGAGAGGGCC
+GGTGACGTTGCCGATATCGCGGAAAGATTGGTTGTAACTGAATATGCGCCCGGCTATCTG
+GTTGGTAGAGTTGTAAACCAGCAGAGTTTGAACGGCTGGCAGCAGCGCGCCATCCGCCGC
+GCCAAGCAGAAACCGCAATAGCGCGAGCTGCCACGGCGTTTGCACAAAAGACATTGGAAT
+CAGCAGCAGTACGGAAATAATCAGCGCGACGATAAGGATCTTTTCCGGGCCAATTCTGTC
+GCCGAGCTTGCCGAGCCGGGGGGCGCTAAGTAATGCCGCCACGCCGGGAACGGACGCTAT
+CATCCCGCTAATGAACGCAATATTACTGACATTTCCCGCGAGTTCGCGCACATAGAGCGT
+CAGGATGGGCGCAATAGACCCCGTCGCCACCTGAATAATCAGCGTGGTGACAAACAGGCT
+TAACACCAGGCGGGGATTTTTTAACGAGGCGACCACTTCCCGAACGTGAAGCATCTCTTT
+TTTGCTCACCGGCAGGAAATTCTCGCGAATAAAAAAGAAGGTGAGCAGAAAACAGATAAA
+CAAAACGCTGGCGGTAATAAAAAAGACCGGGCGAAGGCCGTAATGGTCGGCGAGCAGACC
+GCCCGCAAGTGGGCCAAGCAGAGCGCCGCTGACGCCGCCAGTAGAGAGCGTCCCTAACGC
+CCAGCCGCTTTTGTGGCGCGGCACCTGAGTGGCGATGAGCGCATTGGCGTTGGGAATAAA
+TCCGCCCAGCAGGCCTAATAACGCGCGGAGGATCAGAAATTGCCAGATATTTTGCGCCAT
+GCCCATTAACAGCATCACAATGGCCATGCCGAGAGCGGAACGCAACAGTATGATCTTACG
+CCCTTTACGATCCGCCAGACCGCCCCAAAAAGGGGAAGCGATAGCTGAAAAGAGGAACGT
+AATACTAAAGACCAGCCCGGACCACATGTTGAGCGCGCTATGGCCTGTTACGCCGAGTTG
+CTCAACGTAGAGAGGGAGAAAAGGCATGACCAGACTGAATGCCGCGCCGGTTAAAAAACA
+GCCCAGCCAGGTAACGGTTAGATTGCGTTTCCAGTTTATGGGGACATCAGAGGGTGACAT
+AGTGTTCCACAGTATGATGCGCGTTTTGCGCTATCATCAATTTAATTATGAGCGTACTAA
+TTATAATTATGCGCCGACCTTACCAGCCTCGCAATGTGGGGAGCTTTTAAAGCTAAAAGA
+GGGGAAAAATTGCAGCCTGACGGCTGCAATCCTGTCAATAGCGCGACGGTACGCCTTCAG
+GGCGAGTTTTAAAGCGGCGATGCAGCCACATATACTGCTCTGGCGCCATCATAATGCACT
+GCTCAACAATCTTATTCATCCATGCGGCAGTCGCTTCTGCGCTCTCCAGCGGAGGCGAAT
+ATTCCGCAGGAAGGATGATCAGTTCGTAGCCTTTCCCGTCGGGTTTACGGCGAGGCACGG
+AGGGGATAATACAGGCTTTAGACATGCGCGCGAGCATCCAGGTACCGGAGGTCGTAGCGG
+CCTGGTCGACGGCGAATAACGGTACAAAGACGCTGGCGCGCGGGCCATAATCGTGATCCG
+GCGCATACCAGATCAATTCGCCGCTTTTCAATGCCTTAACCATACCTTTCAGATCTTTGC
+GATCCAACATCGATTTATTGGAGCGTAAGCGCCCCCAGGTCTGTAACCAGTCGAGCAACG
+GATTATCATTCGGGCGATAAACGCCGATACCCGGGTTATGCATACCAAACATGCGGGCGC
+CAAACTCAAGGGTAAGGAAATGTATTCCTACCAGAATGAACCCCAGCCCCTGCGCCTTAA
+CTTCACGGATATGCTCCAGACCGCTCGCTTCCATCCAGCGGTTCACTCGCCGATCGGGCC
+AGAACCAGGCCATGCCGGTTTCCATCACGCCCATACCGACGGATTCAAAGTTTTTGACCA
+CCATGGTGTGGCGTTCCTGCGCGCTCATTTCCGGAAAGCATAATTCAAGGTTGCGATAGG
+CGATTTTCGCGCGGCGTTTCATTACGCGTCGCGCCAGGTGGCCCAATGCGCAACCCAATT
+TATAGATGACCGGGTAGGGGAGTTGCACGACCAACCAAAGCGCGCCTATACCCAACCAGG
+TTAACCAATAGCGCGGGTGCAGTAAGGCCACGGAGAACTTAGGCAACTTCGTCATTTCTA
+TCCTGTCTTTCAACGAACAATTCTCCGTATTCTCGCATCTTTTTGCGTTGAGCAAAAATA
+TGTAGCAGGAGAGTGGCGATTAAATCGACAATTGTTGTTAATTATTTAGCGTAAAGCAGG
+AAATGTAGCGCAAAATGTGTGGATGTAAATTGGCGAGACTTGCCTTATCATGCCTGCCCA
+CTTTATTTTTTGCTGATTGCAGGATACGTACACCATGCCAGTGTTACACAACCGCATCTC
+TAATGACGAGCTGAAAGCCAAAATGCTGGCGGAAAGCGAGCCGCGTACGACAATTTCTTT
+TTATAAATATTTCACTATCGCCTCGCCGCAACAGACGCGGGACGCGTTGTATCAGGTGTT
+TACGGCGTTGGACGTTTTTGGTCGCGTTTACCTGGCGCATGAGGGCATCAATGCGCAAAT
+CAGCGTGCCGCAAAGCAAGGTTGAGACCTTTCGTCAACAGCTTTATACGTTCGACCCCGC
+GCTGGACGGGGTGCGTTTAAATATCGCGCTGGAGGATGACGGAAAGTCATTTTGGGTGCT
+GCGTATGAAAGTTCGCGACCGTATCGTCGCTGACGGTATTGACGATCCGAGTTTTGACGC
+CAGTAATGTCGGCGATTATCTGAAGGCGGCAGATGTGAATGCGATGCTGGACGATCCTGA
+CGCGGTCTTTATTGATATGCGCAACCACTATGAGTATGAAGTCGGCCATTTCGAAAATGC
+TCTGGAAATCCCGGCGGATACGTTTCGTGAACAGTTGCCAAAAGCGGTTGAAATGCTGCG
+GGAACATGCAGATAAAAAGATAGTGATGTACTGTACCGGCGGTATTCGTTGTGAGAAAGC
+CAGCGCCTGGATGAAACACAACGGTTTCAATAAAGTCTGGCATATTGAGGGTGGCATCAT
+TGAGTACGCCCGTCGCGCGCGCGAGCAGGGGCTTCCCGTTCGCTTTATCGGCAAAAACTT
+TGTATTTGATGAGCGAATGGGCGAGCGCATCTCGGATGAGGTTATCGCGCATTGCCATCA
+GTGCGGCGTGTCCTGCGATAGCCATACCAACTGCAAAAACGACGGTTGCCATCTGCTGTT
+TATCCAGTGTCCGCAGTGCGCCAGTAAATTTAACGGCTGCTGTAGTGAACAATGCTGTGA
+AGAGTTGGCCTTGCCGGAGGAAGAACAGCGCCGACGTCGCGCGGGTCGTGAGAACGGCAA
+CAAAATTTTTAATAAATCGCGGGGTCGGCTTAATAGCAAACTGAGCATTCCCGATCCGGC
+TGAGTAATATTTTGCCGGATAGCGGCGTAAAGGCTGCTATCCGGCATTTCGCCAGGCGTT
+ACTTCTGCTGAACGCCTTCTACTGAGATGATAAGCTCCACCTCTTGTGAGGCTGGGCCGA
+GATCGGTAGTTATATTGAAATCTTTCAGCTTAATTTTTCCTTCGGCCTCAAAGCCCGCGC
+GCTTACCGCCCCACGGATCGTCGCCCTGGCCCATCAGCTTCGCTTCCAGCGTCACCGGTT
+TAGTCACGCCATTGAGCGTCAGATTGCCGGTAATATCCAGTTCATCGCCCTCTTTTTTCA
+CGCTGGTAGAGGTGAAGGTTGCCTGCGGGAATTTCGCAACATTAAGAAACTCCGCGCTAC
+GCAGGTGTTTGTCACGTTCGGCATGGTTAGTGTCGACGCTATTGGTGTTAATGGTCACAT
+TCACTTTGTCTGCTGACGGATTTTTTTCGTCAAAAGTGAACGTGCCGTCGAAATCTTTAA
+AGGTGCCGTATAGCCAGCTGTAGCCCAGATGCTGGATGCGGAAATTGACGAACGCATGTT
+GGCCTTCTTTATCAATTTTATACTCCGCCGCCACGGCGGAACCGGTCGTGAATAACAAGG
+ATGCGAGGGTGAATCCCAGCAGGTTTTTTTTCATTTTTGAGCTCCATAGTCAGATGACGA
+CATTCCTGTCATACGTTTCAGTGTGTCGTCTTTATCGATGAAATGGTGTTTTAGCGCCAT
+AACCCCATGCGAGAGCGAGATAATGACCAGCGACCAGGCAAACCACAGATGCAGTGTTCC
+GGCGATGTCAGCCTGCGCGCCCGCGTCCGTAAGCGTGGCCGGAATCTCAAACCAGCCAAA
+GACGCTAATCGGTTTACCGTCGGCGGTGGAAATCAGGTAGCCGCTAATGATTATCGCAAA
+GAGCAGGAGATACAGAAGGATATGACCCGCGGCGGCGCCAATGCGCGTTAAACGGGAATA
+GCTGGTCAACGCAACGGGCGGCGGAGAATAAAGCCGCCAGATAATACGCACGATCAGCGC
+CATCATCAGTAACATGCCAATACTTTTATGTATTTCCGGCGCCTAGTGATACCAGCCGTC
+GTAATAACTGAGCGTGACCATCCATAAACCCAACGCAAACATGCCATAGACCACTAGGGC
+GGTCAGCCAGTGGAGGGCGGCGGAAACTACGCCATAACGTTGTGGAGTATTTTTAAATTG
+CATAAACACACCAATGAATATTTCACGAGAGAATGAAAATGGCGTGGAAAAGCGCCGAAT
+GCAACTTATAAATAAGAATTTGAATGATATTTATTTTTATTTCAATAATTTTGATGTTGT
+TTGCGATTCAGCTTCAGAAGTTTCGAGATATTTCACTCCTGTAACCGCACAACGGCAGGA
+GTTGGCATTATTGCCGTGCTTCAACATTATGAAATAAAAAGTGAGGAACTTTCAGGAAGT
+GTTAGTTAACGTCAATGAAAAGCAATCAGAAGAAAAGGAGATAAACAATATCCATCACCG
+CCAGCAGCGACCAAAGAATAACGTAAAGCATGAAATGTTCGCGAATATTATTCATCAGAA
+AATGAAAGAGACGACGCATAGCTTACCTTAATAAACAGCCCCTTTACGGGGCCGACAAAT
+TATTGGCTAAAACGGGAAAGCCGGAACGGCGTCAGATCAAAGGAGGGCGTTTTTCCCAAC
+GCAAAATCCGCAGCGATTTCTCCTAACACCGGGGCGAATTTAAAACCATGTCCGCTGAGT
+CCAGTGATGACAAGCGTATTCTCATGGCCAGGCAGCGTATCGATAATAAAATCCTCGTCC
+GGCGAATTATCATAGGTACATGCCGCCCCATGTAAACAACCGCCGATACCCGGCAGTACG
+TTACGCAGGAAAGGAAATGCTTCCGCGCCATCGCTGGCAACGGCGGCAAAGGGCTTGCGC
+TCTTCCGGTGCCTGTATTCGCTGCCCGCCATTGTGTTTGCCGATTTTTAACTCGTCGTTC
+TCCGCCGGGAAACCGTAATAGTGATCGCCGTTGGGCATTTCGCCGGTAAAGGCCGGAAAG
+CGGTTTTTAGTGCTGTAACGTCCATCCGCCTTAAACCAGGCAAAAACTTTACGTACGGGC
+TGAACGGGCAGCTCCGGTACCAGCGTTTTGACCCAGGTGCCCGCGCTAATCAGCGCTTTG
+CTGGCGTGGTAGCAGCCTTCACTCGTCTCTATCGTCACACCGTTATCATCATGGTGAATA
+TGGCTTACCGGGCTGTTGAATAGCTGTGCGCAGCCTGCCTCTCGGGCCAGACGAAGCCAT
+GTGGTAATGGCTAATTCGCTGCGCAGGAAACCGGAGTCAGCTTCAAACAGCCCGATATAA
+TTATCGGGCACGCGAATTTCCGGCCAGCGCGTCATGAGGGCCGTCGCGTCCAGGCGCTCG
+ACGTTCAATTGCCACTGTTGCGCGCTTCGTGCGACGTTGGCTAAGAAAGCGGAATCGGCC
+GGGCCGAGGTTGACGACGCCGGAGCGGACAAAAATAGGCTCTTCATTGTGTGTGGAGAGC
+TCATCCCAAAGCGTCTGGGCGCGAAGCACCAGCGGGACATATTTTTCGCCTTCACCATAA
+GCGTGGCGGATAAGACGGGTATCGCCGTGGTGGCTGCCCTGTTGATAAGGCGGCATATGC
+GCATCGGTCATCAGGACCTTTAGCCCGGCGCGGGTGGCGTAATAACCAGCGGCGGCGCCA
+ACCGAACCGCTGCCGATAATAATAAGGTCGTATTTCATCAGCTTCTCTCTGCTATCGCGA
+TGATTTCAAGGTAAATAACTGCGCTGAGATATACAAGCCAGAAATAAGTGAGGCACCTTA
+CGGTGCCTGAGAGAGGGGGAGCGCGTCACGCTAATGGTGACGATACTCGTTTTCCTGGTA
+ATCGCCTGATTCTATTTTGGCGATGCCGGCTTCTAATATTGAAATAAATTGCCTGGCTAC
+ATCTGTCGTTAACCAGAGCGTTTGACCAACTTCAGTCCCTTCCGGTTCCGGACGATTTGG
+GGTCTGGTAGTGTAAACGCAGCATCAGCGCATCATAGCTATCGACGGTGCTGATGTCCCA
+TCCTACAAGCGGATGGGTCTGAATGACTTCATTATTCTTTTCCATCATGCCCCCCTGGTA
+CGTGTTATAAGACAACGGTTCTCGAGGTTCAATGCGTGTTTTTCTTCTGAAGCAACTTCA
+GTATACCAATTAATAAGGCTATTCACTGCGTTTTTAAAGAGACCGGAGGATAAATTTCTC
+TTTTTAAGAATTATATGAACAATAAAGCGGCAGTTCATTCATATTTTTTTAGGATGTTGT
+GCAATTATTTTGACGGTCAGGCGAAATATTCATCAGTTGCGCAAATAAAAAAGCCGGGGC
+GACCCGGCAAACATACATCACTGCATATCATTTTTTATTCATTGATGAACCAGTCATCAG
+CGCTCTCCCAGGTCTCCTGGAGAATCTCGCTAATGCGTTCTTTATCCTCTTTTGACGCGC
+CAATGACGGACAAGTTGTTGGCGGTAGCGTAACGCACGGTGACGTTACCCAAATTCTCAG
+GAAAATGATGGCTAATACGGCGGGNNNNNNNNNNNNNNNNNNNNNNNNNNCCCGCCAGCG
+CACCAATCGCACCGGCAGGCAGAGGTGACGTTTTGGCTATAGTGACTTCAATACGCATAA
+TGGCCCCCTGTTGAATATACTGGATATATATACAGTTAAATCCAATATATAGCAACAGGT
+AAGCGCATTTTTTATTTTTTTACTGACCAGCGTACTGTTTCACCCGCTAAAAAAGGCACC
+AGCGAATCATCAGCCAGCGCGATATTTTCCGGTATCTGTTGTTCATCGCGAACCAGTTCC
+ACCCACCCCGTATTCACCGGCAGGCCATAGAATTGCGGGCCATTCAGTGAACAGAACGCT
+TCAAAGTGCGCCAGCGCGTTCATTTCCTCAAACACGGCGGCATAACTGCCAAGAGCGGAG
+GGGGCGTTGAAACAACCGGCGCAGCCGCAACGGGTCTCTTTACGATGACGTGAATGCGGC
+GCTGAATCCGTCCCCAGGAAGGCGCGCGTAAAACCACTGGCGACCAGGTCGCGTAACGCC
+TGCTGGTGAATATTGCGTTTCAGAATCGGCAGACAGTACAGGTGAGGACGAATGCCGCCA
+ACCAGCATATCATTACGGTTAAACATTAAATGTTGAGGCGTAATGGTCGCCGCCAGGTTG
+TAGCTGCCGTCACGTACATACTGCGCGGCATCTTTGGTTGTGATGTGTTCAAAGACCACT
+TTAAGCGCGGTCAGACGCTGGCGTAGCGGTTCCATTACGGTGTCGATAAAACGCGCTTCG
+CGATCGAAGATATCAACATCCGCATGGGTCACCTCACCGTGGACCAGCAATGGCATTCCG
+AGTTTTTCCATCCGCTCCAGTACCGGCATGATAGCGTCGACTGACGTTACGCCATGACTG
+GAGTTAGTGGTGGCATTGGCCGGGTAAAGCTTGGCCGCAGTAAACACGCCTTCATGGAAA
+CCACGCTCCAGTTCATCGGCATCGAGCGAATCCGTTAAATAGCAGGTCATTAACGGCGTG
+AAATCATGCCCGGCGGGCACCGCATCGAGAATACGCTGGCGGTAGGCGATCGCTGCATCA
+ACGGTCGTAATGGGGGACGCCAGGTTCGGCATCACGATAGCGCGACCATAAATTTCGCTG
+GTATAGGGTACGACCGTTTTTAACATGTCGCCATCGCGAAGGTGAACGTGCCAGTCGTCC
+GGGCGGCGGATCTTTAAAACCTGGGATGGTGCAGTCATTAATAAGCTCCGGCTGAGGAAT
+AGTCTTTTTGCCGGAAACAAAGGATAAGCGGAAACGTTTTCGTTTGCACGTAAAAAAAGG
+GCGCGAGCGCGCCCTCCGAAATCAATTGGTGAAAGGAATAACGATTTCACCAGGTTTAAC
+TTCAATGCCTTTCGCGAGTTTCTTCGCTAACGCTTCGCCTTTACTACTGTCCTCACGCAA
+CACGTAAGCGGGCCGCTGGTTAAAGTAGCTACGTAAAGACTGATTTAAATAGGGCAGGAG
+CGTTTGTAGCACTGATTGCATTTTCTCCGGCGTCACGGTGGCGTCTACTACTTCCATCTC
+CTGAAGATAGATGGCGCCTTTTTCTTTATCAAAGACCGGCAGGGCTTTTAGCTTGAGTTT
+CATCGTCGCTTTTTGACTGCCAAACAGGGAATTCATATCCAGCCTGGCATCGCCAGTAAG
+GGTGACTTTATTAGGCTCTTCCCGACCAATCTGGCTGGCAAGGTTAGTCAATACGATATG
+CGCGTCGGCAATGCCAGGCAGACCAATATCTTTTGAGAAATTATTCCGTTTTTCAAGCGC
+TTGATTGATTTCTTGTTCGCTAATGGTGTATTGCGTAAGTTGATTACAACCCACTAACAG
+GCCGCTAACTACCAGCGCAGCGGCAAAAAAAACTTTTTCATGGCGTTCCTTAGCATGTTG
+CCTGTGCCCTAATCTTGACACAAAGCAGCATGTCGCGCCAGCGGACATGGCGCCACTAAA
+AAAAGCTGAAAAAGGCGGCAAGAAAGGGTTGCCGCCTGGCGGGCGTTAGATAGCCATTGA
+GGAGAGTAAATTAATTTGCGTCTGCTTAGCCATATTATCGCGATAGTCCGCGACTTTTGT
+CGGCCAGTGAATACCGGCGACCAGCGTCAGATTACGCAGAAGCGGAAACAGATGAATATC
+ATCTTCCGATAATTCGCCGTTAACGGCGTTAGGCTGTACGATGAGTTTATCCAGCAAACG
+TAAATCATCGCCGATCTTTTTAATCAGTCCGGCAGAGTGCGCAAGATGGTTGTCAAAACT
+GCCAGATGAGGCCTCTTTTTTGCGGATAAAATACTGGCGCGCCGCAGGGGTAGAAAATTC
+ATCGAAAGCGGATTTTGCAAATCGCGGCAGCAGTAGCTGATTAACGTAACCGTTAACTTT
+GCGCAACCACTCTTCAATGGCTGGATTACGTTTCCCGGTTAACAGCGGTTTGCCGTCGAG
+GTTGTCGACATAATGTACAATATCCATACTTTCAGGAAGGTAGCGACTATCATCTTTTTG
+CAGGATGGGCACCATCTTTTGACCAATCATCCGGGTGGGCGTCGCCTCGTCGTCATTTTG
+TAACACGTTAAGTTCAACGGGGATGTTCTTCAGGCCGAAAATCATGCGGGCTTTAACGCA
+GAAAGGGCAATGATCGTAAATATAAAGCTTCACGTTTCTCCTCCATTTGACTGTCGGTTC
+CTGACCAGTATGGAGGAGATAGCGACAGGTATCAAATCAGGCGCCGGGTTCCAGCATCCG
+GCGCGGCGTGCGCTTATGACTAAATTGCCAGCCTAAAGCCAAAAAGGTGATAAAGCCGAT
+AATACCGAGCATCATCCACGGTAGTTCAGGCTGCGCAAGCGCTTTACCCATATCAAACAA
+CCAGCCGCCGCCGATATAACTAATCGCGCCGCCAATGGCTAATCCCAGACGGCTAAAGCC
+CATATAGCTTCCCCGCGCCCTCGCGTCCGCGGGCGACGCGCTGAGCGTTTCGCGCGCCGG
+TTCGGCGATAACCGAGCCGATGTAGAAAGCGCAAATAAGCGTAAAAAGCTGCTGTAAATT
+GCCCACCATCCCGATGGGGAGCATGCTCAGCGACATGACGAGCAAACCGGCCATCAGCCG
+ATGCTCCAGCCGAAAACGCTTTTCGCTCCAGCGGGCAATCGGGTAGAGCAACGTCAGCGA
+GAGACACGCCTCAATAGCGTACATCCATTTCACGGCAGCAGGCGAACCGGCGATATCGTT
+TACCATAATCGGCAGCATTAACATGACCTGTACCGCCAGCATATAGTAGCCCGCCAGCGT
+CAGCACGTAGGTGACAAACCTTTTATTGCTCATGACGCGGCGCATTCCTTCACGCACCGG
+CGTTCTGGCCGTTGATAGCTTCCAGGCCGGAAGCAGCCATGCGTTGAAAAGGGCGCATAA
+TATGAACAAAATAGCGCCCGTCGCGCAGACCAGGCGAAAATCGTATTGTAGCAACCAGCT
+TCCCAGCAGCGCGCCAATCACCGCGCCCGCGCTGTCCTGCATCATCAACAGAGAGAAGAA
+GCGGCCCCGTTGCTCCGGACGAATTAATTTGACCACCAGCGCTGAACGCGGCGGGTCGAA
+AAGCGTACCGCCGAGACCGGAAAGAAAGCAGGAAAACCACAAGAGCCAGGGCTCATGCGC
+GATACCCATGGTGGCAAAGCCTGCGGCGCGCATCAGCATACCGGTGACAATCATCGGTTT
+CGCGCCAAAGCGATCGGCGATGGCGCCGCCAAAAATGCCCAGACCTTGTTGAATAAACTG
+ACGCAGGCCGAGCGCGATCCCTACCATTACGGCAGCCCACCCCATTTGATCGACAAAGCG
+AATAGAGATGAGCGGGAAGACGACGAAAAAACCCAGCACCACTAACATGTTATCGATGAG
+AAGAAAATATTTACCCAGGTTCCTCGCCTGCGAGACGCGCGACATTTCCCCTCCCGGGAA
+ATAAAAGATGAGCGTCTTCTATTCTGCGGCGGCGTTTCGTTTTTTCCTACCGTTAGCGGG
+ACAATATTTTTTTATCAAAAGTCCTTTTTAATCGAGAGTTTTCATCAAAATGTGGCAGCA
+ATTCAAAAAATGACGATTTGCGCTTTTCACAGGGCCTGGTTGCGCAGGTATAGTAATGTT
+ACTGGCGTGCTGAAGACGTTACAGGAAGGAGTAGGTATAGAATGTTTGGCTATCGCAGTA
+ACGTGCCAAAAGTGCGCTTAACCACCGATCGTCTGGTGGTACGTTTAGTGCATGAGCGTG
+ATGCCTGGCGTCTGGCCGATTATTACGCGGAAAATCGTCATTTTTTAAAACCCTGGGAAC
+CGGTCCGTGATGAAAGTCATTGTTATCCTTCAGGATGGCAGGCGCGTCTGGGAATGATCG
+GTGAATTTCACAAACAGGGCTCCGCCTTCTATTTCGCGCTACTTGATCCGGAAGAAAAAG
+AAATTATCGGCGTGGCGAATTTTTCCAATGTGGTGCGCGGTTCTTTTCATGCCTGTTATC
+TGGGCTATTCCATTGCGCAAGAGTGGCAGGGGCAAGGGCTGATGTTTGAAGCCTTAACCG
+CTGCGATTCGCTATATGCAGCGCACTCAGCATATCCACCGTATCATGGCGAACTATATGC
+CGCACAACAAACGTAGCGGCGCGTTGCTGGCGCGGCTTGGCTTTGAAAAAGAAGGCTATG
+CGAAAGATTACCTGTTGATTGATGGACAATGGCGCGACCATGTCCTGACGGCGTTAACCA
+CGCCGTTATGGACGCCGGGGCGTTGAGCGGCTTACGGAATGAGAGGCAAAGGGAGAAAAC
+GATGAAATATGAATTAACCGCCACTGAAGCGCGAGTGATTGGCTGTCTGCTGGAAAAGCA
+GGTGACAACGCCGGAACAGTATCCGCTTTCCGTCAACGGGGTGGTGACAGCCTGTAATCA
+GAAAACCAACCGTGAACCGGTGATGAACCTGACGGAACAAGAGGTACAAGAACAGCTCGA
+TAACCTGGTGAAACGCCACTTTTTGCGTACGGTCAGCGGGTTTGGCAACCGCGTCACCAA
+ATATGAACAGCGCTTCTGTAATTCCGAATTTGGCGATCTGAAACTTAGCGCGGCGGAAGT
+GGCGCTCGTCACTACGTTGCTGCTGCGCGGCGCGCAAACGCCCGGCGAGTTGCGTAGCCG
+GGCGTCGCGGATGCATGAATTCAGCGATATGGCGGAAGTTGAATCCACGCTGGAACGGCT
+TGCCAGTCGTGAGGACGGCCCGTATGTCGTCCGTCTGGCGCGTGAACCGGGTAAGCGCGA
+AAGCCGCTATATGCACCTTTTTTGCGGCGACGTCGATGAACTGTCTCTCCAGACGTCTGC
+GCCGGAAAGTGCGTCGGGCGATCTTCAGTCGCGCGTCGAAGCGCTGGAAAGCGAAGTGGC
+GGAGTTAAAGCAGCGGCTGGATTCTTTGTTAGCTCACCTGGGAGAGTAATGTGAGAACAT
+TACGGATTGGCATTGTCGTGTTAGGTGGTATTGCGCAGAAGGCCTGGCTGCCGGTATTAA
+CCAACACCGCCGGATGGACGTTACAGGGCGCCTGGTCTCCTTCGCGGGATAAAGCCTTAC
+GTATTTGCGAAAGCTGGCGCATACCGTATGTGGATTCGCTGGCGAATTTAGCGTCCGGCT
+GCGATGCGGTCTTCGTCCACTCCAGTACCGCAAGCCATTATGCCGTGGTCAGCGAACTTC
+TCAACGCTGGCGTCCATGTCTGCGTGGATAAACCGCTGGCGGAAAATCTACGTGATGCCG
+AACGGCTGGTGGCGCTGGCGGCGCAAAAAAAATTGACGCTGATGGTTGGCTTTAATCGCC
+GTTTCGCGCCGCTGTACCGCGAACTGAAGACGCGCCTCGGCACTGCGGCGTCACTGCGTA
+TGGATAAACATCGTACCGATAGCATCGGGCCGCATGACTTACGTTTTACTTTGCTCGATG
+ACTATCTGCATGTCGTGGATACCGTTCTGTGGCTGGCGGGCGGCGAGGCGCGCCTTGCCA
+GCGGCACGTTGCTCACCAGCGAGTCCGGCGAAATGTGCTATGCGGAACATCATTTTTCCG
+CCGACAAATTACAAATTACCACCAGTATGCACCGGCGCGCCGGAAGTCAGCGTGAATCGG
+TCCAGGCCGTCACCGATGGCGGGCTGTATGACGTGACGGATATGCGTGAATGGCGCGAAG
+AGCGCGGGCAGGGTATTCTCATCAAACCCATTCCGGGTTGGCAAACAACGCTTGAGCAGC
+GTGGTTTTGTCGGATGCGCGCGGCATTTCATTGACTGCGTACAAAATCAGACGGTTCCGG
+AAACGGCGGGGGAGCAGGCGATTTTGGCCCAGCGCGTCGTGGAGGCGCTGTGGCGGGACG
+CCATCAGCGAATAATCCTCTGTAACATCTGGCGGTAGTAATTCATCGTAATCCAGGTACT
+ATACCCTCAATAATTCGAGTTGCAGAAAAGCTAACGCACATGCAGCTCGAAGTATGGCGG
+GTATATATGCCCACTCTACATAATACCTCTTTTCACAGTGAATAATGGCAAACCGTGGGG
+AGTCTGTAAGGCCTGATAAGACGTTTTGACGTCGCCGTCAGGCGCAGTGATACAGCCGGA
+TACGGCAGAAGTTGCGTTATCCGGTCGATGGATCAGCCATGCAGGAGTTTTACGCCAGGG
+TCTGGAATACAAAAGAAATGAATTTATTGAAATCGCTGGCTGCCGTCAGCTCGATGACTA
+TGTTTTCACGCGTGTTGGGCTTTGCCCGTGATGCGATTGTCGCCAGAATTTTTGGCGCAG
+GGATGGCGACCGACGCCTTTTTTGTGGCGTTTAAACTTCCCAATCTACTACGCCGGATCT
+TTGCCGAAGGCGCTTTTTCTCAGGCCTTTGTGCCTATCCTGGCGGAATATAAGAGCAAGC
+AGGGTGAAGAAGCGACGCGGATCTTTGTCGCTTACGTTTCCGGCCTGTTGACGCTGGCAT
+TGGCCGTCGTGACGGTGGCCGGTATGCTGGCCGCCCCGTGGGTGATTATGGTAACCGCGC
+CGGGTTTTGCCGATACTGCGGATAAATTTGCGCTGACGACGCAACTGCTGCGGATTACGT
+TTCCCTATATTCTGCTGATCTCGCTGGCTTCACTGGTTGGCGCCATTCTCAACACCTGGA
+ATCGCTTCTCTATTCCCGCTTTTGCGCCGACATTTCTTAATATCAGTATGATCGGTTTTG
+CATTATTCGCCGCGCCATACTTTAATCCGCCGGTGCTGGCGTTAGCCTGGGCAGTCACCG
+TCGGCGGCGTGCTGCAACTGGTGTATCAACTTCCGTATTTGAAAAAGATCGGTATGCTGG
+TGCTGCCGCGCATTAACTTTCACGACACCGGGGCGATGCGGGTGGTCAAACAGATGGGGC
+CGGCGATTTTGGGCGTTTCCGTCAGTCAGATCTCCCTTATCATCAATACCATTTTCGCCT
+CGTTTCTGGCCTCCGGCTCGGTCTCATGGTTGTACTATGCCGATCGGTTGATGGAGTTCC
+CGTCCGGCGTGCTGGGCGTGGCGTTGGGGACCATCCTGTTGCCGTCATTGTCGAAAAGCT
+TTGCCAGCGGCAATCATGATGAGTACTGCCGCCTGATGGACTGGGGGCTGCGTTTGTGCT
+TTTTACTGGCGTTGCCGAGCGCGGTAGCGCTAGGCATTCTGGCGAAGCCGCTGACGGTCT
+CGCTGTTTCAGTACGGTAAATTCACCGCCTTTGATGCGGCGATGACGCAGCGGGCGTTAA
+TCGCCTATTCGGTGGGGCTGATTGGCTTGATCGTCGTAAAAGTGCTGGCCCCGGGCTTCT
+ATTCTCGCCAGGATATTAAAACGCCGGTGAAAATCGCCATCGTGACGTTAATCATGACGC
+AGTTAATGAACCTGGCGTTTATTGGACCGCTGAAACACGCCGGGCTGTCGCTCTCTATTG
+GTCTGGCGGCATGTCTCAATGCGTCGCTGCTGTACTGGCAACTGCGCAAACAGAATATCT
+TTACGCCACAACCGGGGTGGATGTGGTTCCTGATGCGTCTGATCATTTCCGTACTGGTAA
+TGGCCGCCGTGTTGTTCGGCGTGTTGCATATTATGCCGGAGTGGTCGCAAGGGTCGATGC
+TATGGCGTTTGCTGCGTTTGATGGCGGTAGTGATCGCGGGTATCGCGGCCTATTTCGCCG
+CGCTTGCCGTGCTGGGCTTTAAAGTGAAAGAGTTTGTTCGCCGGACGGCGTAAATTCAGT
+GCCTGATAGCGCTGTGCTATCAGGCCTACAAGGCATTCAGGCCGGAAAGGCGCAACGTCG
+CCATCCGGCAATGATTAGATAGATATTTTTTTACCGCCGCGGTGAGAGACGGAAGTCTGA
+CCGTCAGCCCCGTACAAGGTCGGCTCCTGGTGAGGTTTCAGCACCTCCAGCGCCTGTTGA
+TTACGCTCGATTTGCCCTTCCAGCAGCCAGCCGTTGTGCTGGTTGAGGTCGCGCAGATGC
+TGCGTTTTTTCGGTAATCGCCTGCCAGCGCTCTGCAATGTCATCGTTTGCGCTACGCTGC
+GCGTTCTGCTCCAGACGGCGCTGTTGTTCCAGATAATCCAGCGTCGCCAGCAACGAGCTT
+TTTTCTTCTGTAATACGCTGTAGCTGGCTGCCGTTAATCTGGCCTACGGAAAGCTGTTGT
+TGCTCGGCGTCCATCACCGTCTTCAGGTCATTCAGGACGGTGGTCATCTGGTCAAGTATT
+TCTGACAAACGAGTCATACGCTTATTTATTCTGTAAGTAGCTCTGCGCCTCGCGAATGAG
+CGAGTCTGCTATTTTTCCCGTATCCATTTTTAACTCACCGTTACGGATAGCCGTTTTTAA
+TGCTTCGACGCGTTCCATATTAATGTCGCTGACGCCTGGCTGCATAAGCTTCGCTTGCGC
+GTCGCTTAACGTTACGCTGGCGCTCGTCGCGGCGGACGTTTTTTCCTGACGCGTTTTTTG
+TACCGGCGTGTCGCTGGTTTCGCGCGTCTGGACAGTGCTAACGGGTTTCAAAGGTGAGGT
+ACGGTCAATGCTCATTTATTTATCCTCATCGAGGGTTACGTTGTAGCGGCCAGCTACCAT
+CATGGTTGAATATCTCATCGGCAGCCGCGACAAAATCTTTACACAATTATAGGTTAATAA
+GAATATTCCCATCAGAATCGACGGTTCCACTCACGATTTGACCCGATGTCATGCGCACGC
+GCGCATTTTGCGCGACGGCGGCATTATTCATCGCCTGACCTTCCGCATTGACGCTAAACC
+CCTCGCCATTGGCGATGACCTGTACTCGTTGACCCGCTTTGACACGCCAGGCCTGACGTA
+TCATCGTAAGCTGTACCGGCTGCCCGGGAGCGAGATCGCGCAAACTGACGGCATCCTGAA
+TCTGACGGATATCCAGTACCGTCCGCGGCGGTAACTGATCCAGTCTGCCACGTTTTAGCG
+TGACGTTGGCCGGCGTCAATTTTCCGCCGCGCGCGACGGGCGCGGCTACGGCGACATAAT
+TGCCGGTCGCTTGCACATTCACCTGCAAATAACGTTTTTCATTGGCGCAGCGCGCCACCA
+CATTGACGTTGCCCCACAGCTTCGCGCTGCCCGTCATGCTGAAGGCTGGCTGCTCGCAGC
+TCGGTAGCAGATTGGGCGGTGAACGGAGCGTGACAACCACCTCGTCGCTGAAGCCAGCCA
+GACGCTGGGAAAACCACGTGGTCAGCTGGGCGTTGATGTCCTGCGCCATTGTCAGGGGGC
+TGAACAGCAAAGCCGCCACGGCGAATCCTCGTTTTAACGTTTGCATGGTACTTCCCCCTG
+GTTGATGTCATGACAGGATTCTACCCGTGTGAAGCAAGCATCAACGCAATAAATAGCGAC
+GCATTTTGCGTTTATTCCGGCGATAACGCGCGCGTGAAGGCATTTAAGCTGTCGGCTGAA
+TTTTGCCATTTGCGGAGGAGATATGCTCGACAGGCTCGATGCCGCCTTACGATTTCAGCA
+GGAAGCGCTAAATCTGCGCGCGCAACGTCAGGAAATATTAGCGGCGAATATCGCCAATGC
+CGATACGCCGGGGTATCAGGCGCGCGATATTGATTTTGCCAGTGAGTTAAAAAAAGTGAT
+GGTGCGCGGACGGGAAGAAACCGGCGGCGTCGCGTTGTCGTTGACTTCTTCTCGCCATAT
+TCCCGCCCAGGCGGTCTCTTCTCCCGCAGTGGATCTGCTTTACCGCGTACCCGATCAGCC
+TTCTTTGGATGGTAACACCGTAGATATGGACAGGGAACGTACGCAGTTTGCGGATAACAG
+TCTCAAATATCAGATGGGGCTTACCGTTCTGGGTAGCCAACTCAAAGGCATGATGAATGT
+GCTACAGGGAGGAAACTAATTCGTGGCGCTGTTAAACATTTTTGATATTGCCGGATCGGC
+GCTTGCCGCACAGTCCAAGCGGTTGAACGTTGCGGCCAGTAACCTTGCGAATGCGGATAG
+CGTCACCGGCCCGGACGGACAGCCTTATCGCGCCAAACAGGTGGTTTTTCAGGTGGACGC
+CGCGCCGGGTCAAGCCACTGGCGGGGTAAAGGTCGCCAGCGTGATTGAAAGTCAGGCACC
+GGAAAAGCTGGTTTATGAGCCAGGCAATCCGCTGGCGGACGCTAATGGTTACGTCAAAAT
+GCCCAACGTCGATGTGGTCGGCGAAATGGTCAACACGATGTCAGCCTCGCGCAGCTATCA
+GGCAAATATCGAAGTCCTGAATACCGTAAAAAGCATGATGCTTAAAACGCTGACATTAGG
+CCAGTAAAGGAGGCGCGTATGTCTATTGCCGTAAATATGAATGACCCGACCAACACGGGC
+GTCAAAACGACGACCGGCAGCGGGTCGATGACCGGAAGCAACGCTGCCGATCTGCAAAGC
+AGTTTCCTGACCTTACTGGTCGCGCAATTGAAGAACCAGGACCCGACTAACCCATTACAA
+AATAATGAGTTAACGACACAGTTGGCGCAAATCAGTACCGTGAGCGGCATTGAAAAACTG
+AATACGACGCTGGGGGCTATTTCCGGGCAAATCGATAATAGTCAGTCCCTACAGGCGACC
+ACGCTGATTGGACATGGCGTTATGGTGCCTGGCACCACAATTCTGGCGGGTAAAGGCGCG
+GAAGAAGGGGCCGTGACGTCCACGACGCCGTTTGGCGTGGAATTGCAACAGCCTGCGGAC
+AAAGTGACGGCAACCATTACCGATAAAGATGGCCGGGTGGTACGGACGCTGGAGATCGGT
+GAGTTGCGAGCCGGGGTACACACCTTTACCTGGGATGGTAAGCAAACGGACGGAACAACG
+GTACCGAATGGTTCTTACAACATTGCGATTACCGCCAGCAATGGCGGGACGCAACTGGTG
+GCGCAGCCGCTGCAATTCGCTCTGGTACAGGGCGTGACGAAGGGCAGTAACGGCAACCTG
+TTGGATCTGGGTACCTACGGCACCACCACACTCGACGAAGTTCGGCAAATAATCTAAGCC
+CTTACACTTATCAGGAGTCAGTCATGTCTTTTTCTCAAGCGGTTAGCGGCCTGAACGCTG
+CGGCCACCAACCTTGATGTTATCGGTAATAACATCGCCAACTCCGCCACCTATGGCTTTA
+AGTCCGGTACGGCATCATTTGCCGATATGTTCGCCGGTTCCAAAGTGGGGTTGGGCGTAA
+AAGTGGCGGGGATTACCCAGGATTTTACCGACGGTACGACAACGAACACCGGGCGCGGGC
+TGGATGTCGCGATTAGCCAGAACGGTTTTTTCCGCCTGGTAGACAGCAACGGTTCCGTGT
+TCTATAGCCGCAACGGCCAGTTCAAACTGGACGAGAACCGTAACCTGGTCAATATGCAGG
+GGATGCAGTTGACCGGCTATCCGGCCACCGGTACGCCGCCGACCATTCAGCAGGGGGCGA
+ATCCTGCGCCGATCACCATTCCGAACACGCTGATGGCGGCGAAATCGACCACCACCGCGT
+CAATGCAGATCAACCTGAACTCAACGGACCCTGTACCGTCTAAAACGCCCTTTAGCGTGA
+GTGATGCGGATTCGTATAACAAAAAAGGCACCGTCACCGTTTATGACAGCCAGGGTAATG
+CCCATGACATGAACGTCTATTTTGTGAAAACCAAAGATAATGAATGGGCTGTGTACACCC
+ATGACAGCAGCGATCCTGCAGCCACTGCGCCAACAACGGCGTCCACTACGCTGAAATTCA
+ATGAAAACGGGATTCTGGAGTCTGGCGGTACGGTGAACATCACCACCGGTACGATTAATG
+GCGCGACAGCGGCCACCTTCTCCCTCAGCTTCCTTAACTCCATGCAGCAGAACACCGGGG
+CTAATAACATCGTCGCCACCAATCAAAACGGCTATAAGCCTGGCGACCTGGTGAGCTACC
+AGATTAACAATGATGGCACCGTGGTTGGCAACTACTCCAACGAGCAGGAGCAGGTGCTGG
+GGCAGATTGTGCTGGCTAACTTCGCCAACAACGAAGGTCTGGCATCCCAGGGCGATAACG
+TCTGGGCGGCGACGCAGGCCTCCGGGGTAGCGCTGCTGGGGACTGCCGGTTCCGGCAACT
+TCGGTAAGCTGACGAACGGCGCGCTGGAAGCCTCTAACGTGGATTTGAGTAAAGAGCTGG
+TGAATATGATCGTCGCGCAGCGTAACTACCAGTCGAATGCGCAGACCATCAAAACCCAGG
+ACCAGATCCTCAATACGCTGGTTAACCTGCGCTAAGCGCCTGACGGGATAGCTTAATGGA
+TCACGCAATTTATACCGCCATGGGGGCGGCCAGCCAGACGCTTAACCAGCAGGCGGTAAC
+GGCCAGCAACCTGGCTAATGCCTCAACGCCGGGCTTTCGCGCGCAGCTTAACGCGCTACG
+CGCGGTGCCCGTTGATGGCCTCTCTTTAGCGACGCGCACGTTGGTTACGGCGTCGACGCC
+GGGGGCGGATATGACCCAGGGTCAGTTGGACTACACTTCCCGCCCGCTGGATGTTGCGTT
+ACAGCAGGACGGCTGGCTGGTGGTGCAAGCGGCGGATGGCGCTGAAGGATATACCCGTAA
+CGGGAATATCCAGGTGGGCCCGACCGGGCAGTTAACCATTCAGGGACATCCGGTTATCGG
+CGAAGGCGGCCCGATTACCGTTCCGGAAGGGTCGGAAATCACCATTGCGGCAGACGGCAC
+GATCTCCGCGCTCAATCCCGGCGACCCGCCAAACACGGTGGCGCCCGTTGGGCGGCTGAA
+GCTGGTCAAAGCGGAAGGCAATGAGGTGCAGCGGAGCGATGACGGTTTATTCCGCCTTAC
+CGCCGAGGCACAGGCTGAACGCGGGGCGGTACTGGCCGCCGACCCGTCAATTCGCATTAT
+GTCGGGCGTGCTGGAGGGCAGTAACGTCAAGCCGGTTGAAGCCATGACCGACATGATCGC
+CAACGCACGTCGTTTTGAAATGCAGATGAAGGTTATCACCAGCGTAGATGAGAACGAAGG
+GCGAGCTAACCAACTGCTGTCGATGAGTTAATACAGGACATTTTATGATCAGTTCATTAT
+GGATCGCCAAAACCGGTCTGGACGCGCAGCAAACCAATATGGATGTGATTGCCAATAACC
+TGGCAAACGTCAGCACCAATGGTTTTAAGCGTCAGCGCGCGGTATTTGAAGATCTGTTGT
+ATCAGACCATCCGCCAGCCGGGCGCGCAGTCGTCCGAGCAGACGACGCTGCCTTCCGGGC
+TGCAAATCGGTACCGGCGTGCGTCCGGTCGCCACGGAGCGCCTGCACAGTCAGGGGAACC
+TGTCGCAGACCAACAACAGTAAAGATGTGGCGATTAAAGGGCAGGGCTTTTTCCAGGTCA
+TGCTGCCGGACGGTACGTCTGCCTATACCCGCGACGGCTCTTTCCAGGTGGATCAGAATG
+GTCAACTGGTGACGGCGGGCGGTTTTCAGGTGCAGCCGGCAATCACCATTCCGGCCAACG
+CGTTAAGCATCACGATTGGCCGCGACGGCGTGGTCAGCGTTACCCAGCAAGGGCAGGCCG
+CGCCGGTTCAGGTCGGGCAGCTTAACCTGACCACCTTTATGAACGACACCGGTCTGGAAA
+GCATCGGCGAGAACCTCTATATCGAAACGCAATCGTCCGGCGCGCCGAACGAAAGCACGC
+CGGGGCTCAACGGCGCGGGGTTGTTGTATCAAGGGTATGTCGAAACGTCGAACGTTAACG
+TGGCGGAAGAGCTGGTGAACATGATTCAGGTTCAACGCGCCTATGAAATTAACAGTAAAG
+CAGTATCGACGACCGATCAGATGCTGCAGAAACTGACGCAACTCTAAGGGGCCGCCGGTG
+GGGGATACGCCACCGGCTCCCTGATTTTGAAGATGAAGGTAATGCAAAAATACGCGCTTC
+ACGCTTACCCAGTTATGGCCCTGATGGTCGCGACGCTGACAGGATGCGCCTGGATACCCG
+CTAAACCGCTCGTGCAGGGGGCGACCACGGCGCAGCCGATACCTGGCCCGGTACCGGTGG
+CGAATGGCTCCATATTTCAGTCTGCGCAGCCGATTAATTATGGCTATCAGCCGCTTTTTG
+AAGATCGTCGACCGCGTAATATCGGCGATACGCTCACGATTGTGTTACAGGAAAACGTCA
+GCGCCAGTAAAAGCTCGTCGGCAAATGCCAGCCGCGACGGCAAAACCAGCTTTGGTTTTG
+ATACGGTACCGCGTTATCTGCAGGGATTATTCGGTAATTCCCGCGCGGATATGGAGGCCT
+CCGGCGGCAACTCTTTTAATGGTAAAGGCGGCGCGAATGCCAGCAATACCTTTAGCGGCA
+CGCTGACCGTGACCGTCGATCAGGTTCTGGCCAATGGCAATTTACACGTCGTGGGGGAAA
+AACAGATCGCGATTAATCAGGGAACGGAATTCATCCGCTTCTCCGGCGTGGTAAATCCAC
+GCACCATCAGCGGTAGCAACTCTGTTCCCTCGACACAGGTGGCGGATGCGCGGATTGAAT
+ATGTCGGGAACGGCTATATTAACGAAGCGCAAAATATGGGCTGGCTGCAACGTTTCTTCC
+TTAATTTGTCGCCGATGTAAGCGAGGTGTATGTGTTTAAAGCTCTTGCAGGAATCGTTCT
+GGCACTGGTTGCCACTCTGGCGCACGCCGAGCGTATCCGGGATCTGACCAGTGTCCAGGG
+AGTACGGGAAAACTCGCTGATCGGCTACGGGCTGGTGGTCGGGCTGGACGGTACGGGCGA
+CCAGACGACCCAGACGCCATTTACCACCCAGACGCTGAATAACATGCTGTCACAACTGGG
+GATTACGGTCCCCACCGGCACCAATATGCAGTTGAAAAACGTGGCGGCGGTGATGGTGAC
+GGCGTCGTATCCGCCTTTTGCGCGACAGGGACAAACGATCGATGTCGTCGTTTCCTCAAT
+GGGGAACGCTAAAAGTCTGCGTGGCGGGACGTTATTAATGACGCCGTTAAAAGGGGTGGA
+CAGCCAGGTGTATGCTCTGGCGCAGGGCAATATTCTGGTCGGCGGCGCGGGCGCTTCCGC
+AGGCGGCAGTAGCGTGCAGGTTAACCAGCTTAATGGCGGGCGCATCACTAATGGCGCGAT
+TATCGAACGCGAGTTGCCGACTCAGTTCGGCGCTGGCAACACCATTAATCTGCAATTGAA
+CGACGAAGATTTTACGATGGCGCAGCAAATTACCGACGCCATCAACCGCGCCCGCGGTTA
+CGGCAGCGCCACTGCGCTTGATGCGCGAACGGTACAGGTACGCGTGCCCAGCGGCAACAG
+CTCGCAGGTGCGTTTTCTGGCGGACATTCAAAATATGGAAGTCAACGTGACGCCGCAGGA
+TGCAAAAGTCGTGATCAACTCGCGTACCGGTTCGGTGGTCATGAATCGGGAAGTCACGCT
+GGATAGCTGCGCTGTGGCGCAGGGCAATTTGTCAGTGACAGTCAATCGCCAACTCAACGT
+CAACCAGCCGAATACGCCATTTGGCGGCGGGCAGACCGTGGTGACGCCACAGACTCAGAT
+AGATTTGCGTCAGAGCGGCGGATCGCTACAGAGCGTGCGTTCCAGCGCCAATCTGAACAG
+CGTAGTGCGCGCGCTGAATGCGCTTGGCGCGACGCCGATGGATCTGATGTCGATTTTGCA
+GTCCATGCAGAGCGCGGGCTGTCTACGCGCCAAACTGGAAATCATCTGATGATCGGAGAC
+GGTAAATTGCTGGCCAGCGCGGCCTGGGATGCGCAATCTCTGAACGAACTGAAAGCGAAA
+GCGGGCCAGGACCCGGCGGCGAATATCCGTCCTGTGGCCCGTCAGGTGGAAGGGATGTTT
+GTGCAGATGATGCTGAAAAGTATGCGCGAGGCTTTACCCAAAGATGGTTTATTCAGCAGC
+GATCAGACGCGTCTGTATACCAGCATGTATGACCAGCAGATCGCCCAGCAGATGACCGCC
+GGTAAGGGATTGGGGCTGGCGGATATGATGGTTAAACAGATGACGGGCGGGCAGACGATG
+CCTGCAGATGATGCGCCGCAAGTACCGCTTAAATTCTCCCTGGAGACGGTAAACAGCTAT
+CAAAATCAGGCGCTGACCCAACTGGTGCGCAAAGCCATACCGAAAACGCCGGACAGCAGC
+GATGCGCCGCTCTCCGGCGACAGTAAAGACTTTCTGGCCCGGCTTTCGCTCCCGGCGAGG
+CTGGCCAGCGAACAAAGCGGGGTGCCGCATCATCTGATTCTGGCGCAGGCGGCGCTGGAG
+TCCGGCTGGGGGCAGCGGCAAATCCTGCGGGAGAATGGCGAACCCAGCTATAACGTATTT
+GGCGTGAAAGCGACCGCCAGTTGGAAAGGGCCGGTGACGGAAATCACCACCACTGAATAC
+GAAAATGGCGAAGCGAAAAAAGTGAAAGCGAAATTCCGCGTCTATAGCTCGTATCTGGAG
+GCGTTATCGGATTATGTCGCGCTGTTAACGCGTAACCCACGCTACGCTGCCGTGACCACT
+GCCGCCACGGCAGAGCAGGGCGCAGTGGCTCTGCAAAACGCCGGATACGCCACTGACCCG
+AATTACGCGCGTAAATTGGCCAGCATGATTCAGCAGTTGAAAGCGATGAGTGAAAAGGTC
+AGCAAAACCTACAGCGCGAATCTCGACAATCTCTTTTAAATTGCTCAAGTCCACGTAGTC
+GCTGCCGATAACAACGAGTATTGAAGGATTAAAAGGAACCATCATGTCCAGCTTGATTAA
+TCACGCCATGAGCGGACTTAACGCCGCGCAGGCCGCGTTAAATACGGTCAGTAATAACAT
+CAACAATTATAACGTTGCGGGTTATACCCGGCAGACAACTATTCTGGCGCAGGCAAACAG
+TACGTTAGGGGCTGGCGGCTGGATAGGTAATGGCGTTTACGTTTCAGGCGTACAGCGCGA
+ATATGATGCGTTTATCACTAATCAGCTACGCGGCGCGCAAAACCAGAGCAGCGGCTTAAC
+CACGCGCTATGAACAAATGTCGAAAATCGACAACCTGCTGGCCGATAAATCCAGCTCACT
+GTCTGGCTCGCTGCAGAGTTTTTTTACCAGCCTGCAAACGTTAGTCAGTAATGCGGAAGA
+TCCTGCGGCGCGTCAGGCGCTGATTGGTAAAGCGGAAGGGCTGGTAAACCAGTTCAAAAC
+CACCGATCAGTATCTGCGCGATCAGGATAAACAGGTCAATATCGCGATTGGCTCCAGCGT
+GGCGCAAATCAACAATTACGCGAAGCAGATAGCTAACCTGAACGATCAAATCTCCCGTAT
+GACGGGCGTAGGCGCGGGCGCATCGCCGAACGACCTGCTCGATCAACGTGATCAGTTGGT
+TAGCGAGCTTAACAAGATCGTTGGCGTCGAGGTGAGTGTACAGGACGGCGGCACCTATAA
+CCTGACGATGGCCAATGGCTATACGCTGGTGCAGGGGTCGACGGCGCGTCAGTTGGCGGC
+GGTTCCCTCCAGCGCCGACCCGACGCGAACGACTGTCGCTTATGTCGATGAGGCCGCCGG
+TAACATCGAAATTCCGGAAAAGTTGCTGAACACCGGTTCGCTCGGCGGGCTACTGACGTT
+CCGTTCTCAGGATCTGGATCAGACTCGTAATACGCTGGGCCAGTTGGCGTTGGCGTTTGC
+CGATGCGTTTAACGCGCAGCATACCAAAGGTTATGACGCCGACGGCAATAAAGGGAAAGA
+CTTCTTTAGCATTGGCTCGCCGGTGGTATATAGCAACAGTAATAATGCCGATAAAACGGT
+ATCGCTAACCGCTAAGGTGGTCGACAGCACGAAGGTTCAGGCGACGGATTATAAGATTGT
+TTTTGACGGTACAGACTGGCAGGTTACTCGCACTGCGGATAACACCACCTTCACGGCAAC
+AAAAGATGCTGACGGAAAACTGGAGATTGACGGTCTGAAAGTGACGGTAGGGACTGGCGC
+ACAGAAAAACGACAGTTTTCTTCTCAAGCCGGTCAGCAATGCTATCGTCGACATGAACGT
+TAAAGTGACAAATGAAGCCGAGATTGCGATGGCGTCTGAGTCAAAACTCGATCCTGATGT
+GGATACCGGCGACAGCGATAACCGCAATGGTCAGGCATTGCTGGACTTACAAAACAGCAA
+TGTAGTGGGCGGCAACAAAACCTTTAACGATGCTTACGCCACGTTGGTCAGCGATGTGGG
+TAACAAAACGTCAACGCTGAAAACCAGCAGCACCACGCAGGCGAATGTGGTTAAACAGCT
+TTATAAACAGCAACAGTCGGTTTCCGGCGTTAACCTCGACGAAGAGTACGGCAATTTGCA
+GCGTTATCAGCAGTATTATCTGGCGAATGCGCAAGTATTGCAGACCGCGAATGCGCTGTT
+TGATGCGTTATTGAATATTCGCTAAAGGAGAAGGATGACATGCGTATCAGTACCCAGATG
+ATGTACGAACAAAATATGAGCGGCATCACTAATTCTCAGGCCGAATGGATGAAGCTGGGC
+GAGCAGATGTCTACCGGTAAGCGCGTTACCAACCCATCTGACGATCCGATCGCCGCGTCG
+CAGGCGGTAGTACTCTTTCAGGCGCAGGCGCAGAATAGCCAGTACGCCCTGGCGCGTACG
+TTTGCCACCCAAAAAGTGTCGCTGGAAGAAAGCGTACTCAGTCAGGTGACGACGGCGATT
+CAAACCGCGCAGGAAAAAATCGTCTATGCCGGAAACGGCACGTTAAGCGACGATGACCGC
+GCGTCGCTGGCGACGGATTTACAGGGGATCCGCGATCAGCTGATGAACCTGGCAAACAGC
+ACTGACGGCAATGGTCGCTATATCTTTGCCGGGTATAAAACGGAAGCGGCGCCATTCGAC
+CAGGCGACAGGTGGTTATCATGGCGGCGAGAAAAGTGTTACCCAGCAGGTGGATTCCGCA
+CGCACGATGGTAATTGGCCATACGGGAGCGCAAATTTTTAATAGCATCACCAGCAATGCG
+GTGCCGGAACCGGATGGCTCGGACTCCGAAAAGAATCTGTTTGTCATGCTCGATACGGCA
+ATTGCCGCGCTCAAGACCCCGGTGGAAGGCAATGACGTGGAAAAAGAAAAAGCCGCTGCC
+GCCATTGATAAAACCAATCGCGGCTTAAAAAATTCGCTTAATAACGTCCTGACCGTTCGT
+GCGGAACTGGGAACGCAACTGAGCGAACTCAGTACGCTGGATTCACTGGGAAGCGACCGT
+GCGCTGGGACAGAAGCTACAGATGAGCAACCTGGTAGATGTGGACTGGAACTCGGTCATT
+TCCTCCTACGTCATGCAACAGGCGGCATTACAGGCGTCCTATAAAACGTTTACCGACATG
+CAGGGAATGTCGCTTTTCCAGTTGAACCGGTAACGCCTCTTTTTGAAACATATCACGAAA
+CTGGATATGTTTTGTCTGCCCGCGCCATCCACCCCGGCGCGGGCATTTTTTGTCTATGGA
+AAACCCCCAGCTAGGCTGGGGGTTCCGGAAAGCTTTCAGCTTTAAGCCAGTTATTAAAAC
+CCCTTTTGATTTGTTAAAACATCTTGCGGTCTGGC
\ No newline at end of file
diff --git a/t/data/real_data_2.gff b/t/data/real_data_2.gff
new file mode 100644
index 0000000..100910e
--- /dev/null
+++ b/t/data/real_data_2.gff
@@ -0,0 +1,1641 @@
+##gff-version 3
+##sequence-region ERS222222|SC|contig000020 1 92255
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 241 921 . - 0 ID=22222_2#22_04055;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002145956.2,protein motif:Pfam:PF07108.5;locus_tag=22222_2#22_04055;product=pathogenicity island-encoded protein A,PipA protein;protein_id=gnl|SC|22222_2#22_04055
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 1144 2019 . - 0 ID=22222_2#22_04056;gene=pipB2_2;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002145957.1,similar to AA sequence:UniProtKB:Q8ZMM8,protein motif:CLUSTERS:PRK15197,protein motif:Cdd:COG5351,protein motif:Pfam:PF00805.16;locus_tag=22222_2#22_04056;product=secreted effector protein,Type III effector pipB2,secreted effector protein PipB,Uncharacterized protein conserved in bacteria,Pentapeptide repeat [...]
+ERS222222|SC|contig000020 Infernal:1.1 ncRNA 2139 2237 . + 0 ID=22222_2#22_04057;inference=COORDINATES:profile:Infernal:1.1;locus_tag=22222_2#22_04057;product=isrI
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 2567 2908 . - 0 ID=22222_2#22_04058;gene=sigE;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002145959.1,similar to AA sequence:UniProtKB:O30917,protein motif:CLUSTERS:PRK15202,protein motif:Pfam:PF07824.6;locus_tag=22222_2#22_04058;product=chaperone protein SigE,Chaperone protein sigE,type III secretion chaperone protein SigE,Type III secretion chaperone domain;protein_id=gnl|SC|22222_2#22_04058
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 2925 4610 . - 0 ID=22222_2#22_04059;eC_number=3.1.3.-,3.1.3.-;gene=sopB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002145960.1,similar to AA sequence:UniProtKB:O30916,protein motif:CLUSTERS:PRK15378,protein motif:Pfam:PF05925.6;locus_tag=22222_2#22_04059;product=inositol phosphate phosphatase SopB,Inositol phosphate phosphatase sopB,inositol phosphate phosphatase SopB,Enterobacterial virulence protein IpgD;pro [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 5332 6801 . - 0 ID=22222_2#22_04060;eC_number=3.4.-.-;gene=pepD_2;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002215025.1,similar to AA sequence:UniProtKB:Q8G6Z9,protein motif:Pfam:PF03577.9;locus_tag=22222_2#22_04060;product=peptidase family C69,Dipeptidase,Peptidase family C69;protein_id=gnl|SC|22222_2#22_04060
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 6974 8338 . - 0 ID=22222_2#22_04061;eC_number=2.7.13.3;gene=yedV;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002145964.1,similar to AA sequence:UniProtKB:P76339,protein motif:CLUSTERS:PRK09835,protein motif:Cdd:COG5278,protein motif:TIGRFAMs:TIGR01386,protein motif:Pfam:PF02518.20;locus_tag=22222_2#22_04061;product=heavy metal sensor kinase subfamily,Probable sensor-like histidine kinase YedV,sensor kinase CusS [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 8331 9068 . - 0 ID=22222_2#22_04062;gene=copR;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002243090.1,similar to AA sequence:UniProtKB:P76340,protein motif:CLUSTERS:PRK11517,protein motif:Cdd:COG4565,protein motif:TIGRFAMs:TIGR01387,protein motif:Pfam:PF00072.18;locus_tag=22222_2#22_04062;product=transcriptional regulatory protein YedW,Probable transcriptional regulatory protein YedW,transcriptional regulatory [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 9147 9557 . + 0 ID=22222_2#22_04063;eC_number=3.5.2.17,3.5.2.17;gene=uraH;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002145966.1,similar to AA sequence:UniProtKB:Q4VYA5,protein motif:CLUSTERS:PRK15036,protein motif:TIGRFAMs:TIGR02962,protein motif:Pfam:PF00576.15;locus_tag=22222_2#22_04063;product=hydroxyisourate hydrolase,5-hydroxyisourate hydrolase precursor,hydroxyisourate hydrolase,hydroxyisourate hydrolas [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 9890 10402 . - 0 ID=22222_2#22_04064;eC_number=1.5.1.36;gene=hpaC;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729827.1,similar to AA sequence:UniProtKB:Q57501,protein motif:CLUSTERS:PRK15486,protein motif:TIGRFAMs:TIGR02296,protein motif:Pfam:PF01613.12;locus_tag=22222_2#22_04064;product=4-hydroxyphenylacetate 3-monooxygenase coupling protein,4-hydroxyphenylacetate 3-monooxygenase reductase component,4-hydro [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 10420 11652 . - 0 ID=22222_2#22_04065;eC_number=1.14.14.9;gene=hpaB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002145968.1,similar to AA sequence:UniProtKB:Q57160,protein motif:TIGRFAMs:TIGR02310,protein motif:Pfam:PF03241.7;locus_tag=22222_2#22_04065;product=4-hydroxyphenylacetate 3-monooxygenase%2C oxygenase component,4-hydroxyphenylacetate 3-monooxygenase oxygenase component,4-hydroxyphenylacetate 3-monooxy [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 11833 12273 . - 0 ID=22222_2#22_04066;gene=hpaR;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002145969.1,similar to AA sequence:UniProtKB:O07458,protein motif:TIGRFAMs:TIGR02337,protein motif:Pfam:PF01047.16;locus_tag=22222_2#22_04066;product=homoprotocatechuate degradation operon regulator%2C HpaR,Benzoate anaerobic degradation regulator,homoprotocatechuate degradation operon regulator%2C HpaR,MarR family;prote [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 12548 13837 . + 0 ID=22222_2#22_04067;eC_number=5.3.3.-;gene=hpaG;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729830.1,similar to AA sequence:UniProtKB:P37352,protein motif:CLUSTERS:PRK15203,protein motif:Cdd:COG0179,protein motif:TIGRFAMs:TIGR02303,protein motif:Pfam:PF01557.12;locus_tag=22222_2#22_04067;product=4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase,Homoprotocatechuate cata [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 13834 14133 . + 0 ID=22222_2#22_04068;eC_number=1.2.1.8;gene=hpcC_1;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729831.1,similar to AA sequence:UniProtKB:Q9HTJ1,protein motif:CLUSTERS:PRK13252,protein motif:Cdd:COG3191,protein motif:TIGRFAMs:TIGR02299,protein motif:Pfam:PF00171.1;locus_tag=22222_2#22_04068;product=5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase,Betaine aldehyde dehydrogenase,bet [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 14127 15299 . + 0 ID=22222_2#22_04069;eC_number=1.2.1.-;gene=hpcC_2;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729831.1,similar to AA sequence:UniProtKB:P23105,protein motif:CLUSTERS:PRK13252,protein motif:Cdd:COG4230,protein motif:TIGRFAMs:TIGR02299,protein motif:Pfam:PF00171.1;locus_tag=22222_2#22_04069;product=5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase,2-hydroxymuconic semialdehyde dehy [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 15301 16152 . + 0 ID=22222_2#22_04070;eC_number=1.13.11.15,1.13.11.15;gene=hpcB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729832.1,similar to AA sequence:UniProtKB:Q05353,protein motif:CLUSTERS:PRK03881,protein motif:Cdd:COG0179,protein motif:TIGRFAMs:TIGR02298,protein motif:Pfam:PF02900.1;locus_tag=22222_2#22_04070;product=3%2C4-dihydroxyphenylacetate 2%2C3-dioxygenase,3%2C4-dihydroxyphenylacetate 2%2C3-d [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 16162 16542 . + 0 ID=22222_2#22_04071;eC_number=5.3.3.10,5.3.3.10;gene=hpcD;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729833.1,similar to AA sequence:UniProtKB:Q05354,protein motif:CLUSTERS:PRK15031,protein motif:Cdd:COG3232,protein motif:Pfam:PF02962.1;locus_tag=22222_2#22_04071;product=5-carboxymethyl-2-hydroxymuconate delta-isomerase,5-carboxymethyl-2-hydroxymuconate Delta-isomerase,5-carboxymethyl-2-hy [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 16686 17489 . + 0 ID=22222_2#22_04072;eC_number=4.2.-.-,4.2.1.80;gene=hpcG;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729834.1,similar to AA sequence:UniProtKB:Q9S156,protein motif:CLUSTERS:PRK11342,protein motif:Cdd:COG3971,protein motif:TIGRFAMs:TIGR02312,protein motif:Pfam:PF01557.12;locus_tag=22222_2#22_04072;product=2-oxo-hepta-3-ene-1%2C7-dioic acid hydratase,2-keto-4-pentenoate hydratase,2-keto-4-pen [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 17500 18291 . + 0 ID=22222_2#22_04073;eC_number=4.1.2.-;gene=hpaI;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_216043.1,similar to AA sequence:UniProtKB:Q47098,protein motif:CLUSTERS:PRK10128,protein motif:Cdd:COG2301,protein motif:TIGRFAMs:TIGR02311,protein motif:Pfam:PF03328.8;locus_tag=22222_2#22_04073;product=4-hydroxyphenylacetate catabolism,4-hydroxy-2-oxo-heptane-1%2C7-dioate aldolase,2-keto-3-deoxy-L-rha [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 18363 19739 . + 0 ID=22222_2#22_04074;gene=hpaX;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729836.1,similar to AA sequence:UniProtKB:P76470,protein motif:CLUSTERS:PRK11551,protein motif:Cdd:COG2814,protein motif:TIGRFAMs:TIGR02332,protein motif:Pfam:PF07690.10;locus_tag=22222_2#22_04074;product=4-hydroxyphenylacetate permease,Inner membrane transport protein RhmT,putative 3-hydroxyphenylpropionic transporte [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 19749 20645 . + 0 ID=22222_2#22_04075;gene=hpaA;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729837.1,similar to AA sequence:UniProtKB:P40408,protein motif:CLUSTERS:PRK10572,protein motif:Cdd:COG2169,protein motif:TIGRFAMs:TIGR02297,protein motif:Pfam:PF12833.1;locus_tag=22222_2#22_04075;product=4-hydroxyphenylacetate 3-monooxygenase operon regulatory protein,Bacillibactin transport regulator,DNA-binding tran [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 20659 21597 . + 0 ID=22222_2#22_04076;eC_number=3.1.26.11,3.1.26.11;gene=rnz;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_006087376.1,similar to AA sequence:UniProtKB:P54548,protein motif:CLUSTERS:PRK00055,protein motif:Cdd:COG5212,protein motif:TIGRFAMs:TIGR02651,protein motif:Pfam:PF12706.1;locus_tag=22222_2#22_04076;product=Ribonuclease Z,Ribonuclease Z,ribonuclease Z,Low-affinity cAMP phosphodiesterase,ribon [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 23021 23326 . - 0 ID=22222_2#22_04077;gene=cbpM;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_001570915.1,similar to AA sequence:UniProtKB:P63264,protein motif:CLUSTERS:PRK10265;locus_tag=22222_2#22_04077;product=chaperone-modulator protein CbpM,Chaperone modulatory protein CbpM,chaperone-modulator protein CbpM;protein_id=gnl|SC|22222_2#22_04077
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 23326 24246 . - 0 ID=22222_2#22_04078;gene=cbpA;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729840.1,similar to AA sequence:UniProtKB:P36659,protein motif:CLUSTERS:PRK10266,protein motif:Cdd:COG5407,protein motif:TIGRFAMs:TIGR02349,protein motif:Pfam:PF01556.12;locus_tag=22222_2#22_04078;product=curved DNA-binding protein,Curved DNA-binding protein,curved DNA-binding protein CbpA,Preprotein translocase subun [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 24482 24844 . + 0 ID=22222_2#22_04079;gene=scsA;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729841.1;locus_tag=22222_2#22_04079;product=copper-sensitivity suppressor membrane protein A;protein_id=gnl|SC|22222_2#22_04079
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 24893 26779 . + 0 ID=22222_2#22_04080;eC_number=1.8.1.8;gene=scsB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729842.1,similar to AA sequence:UniProtKB:P36655,protein motif:CLUSTERS:PRK00293,protein motif:Cdd:COG4233,protein motif:Pfam:PF02683.9;locus_tag=22222_2#22_04080;product=copper-sensitivity suppressor membrane protein B,Thiol:disulfide interchange protein DsbD precursor,thiol:disulfide interchange pr [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 26776 27399 . + 0 ID=22222_2#22_04081;gene=scsC;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729843.1,similar to AA sequence:UniProtKB:O32218,protein motif:Cdd:COG1651,protein motif:Pfam:PF01323.14;locus_tag=22222_2#22_04081;product=copper-sensitivity secreted suppressor protein C,Thiol-disulfide oxidoreductase D,Protein-disulfide isomerase,DSBA-like thioredoxin domain;protein_id=gnl|SC|22222_2#22_04081
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 27389 27895 . + 0 ID=22222_2#22_04082;gene=resA;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002145985.1,similar to AA sequence:UniProtKB:P35160,protein motif:CLUSTERS:PRK03147,protein motif:TIGRFAMs:TIGR00385,protein motif:Pfam:PF08534.4;locus_tag=22222_2#22_04082;product=suppressor for copper-sensitivity D,Thiol-disulfide oxidoreductase resA,thiol-disulfide oxidoreductase,periplasmic protein thiol:disulfide ox [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 28028 29269 . + 0 ID=22222_2#22_04083;eC_number=3.1.3.10;gene=agp;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_001570908.1,similar to AA sequence:UniProtKB:P19926,protein motif:CLUSTERS:PRK10173,protein motif:Pfam:PF00328.1;locus_tag=22222_2#22_04083;product=glucose-1-phosphatase/inositol phosphatase,Glucose-1-phosphatase precursor,glucose-1-phosphatase/inositol phosphatase,Histidine phosphatase superfamily (bra [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 29303 29530 . - 0 ID=22222_2#22_04084;gene=yccJ;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_006087385.1,similar to AA sequence:UniProtKB:P0AB14,protein motif:CLUSTERS:PRK10174;locus_tag=22222_2#22_04084;product=YccJ-like protein,hypothetical protein,hypothetical protein;protein_id=gnl|SC|22222_2#22_04084
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 29551 30147 . - 0 ID=22222_2#22_04085;gene=wrbA;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729847.1,similar to AA sequence:UniProtKB:P0A8G6,protein motif:CLUSTERS:PRK03767,protein motif:TIGRFAMs:TIGR01755,protein motif:Pfam:PF03358.9;locus_tag=22222_2#22_04085;product=trp repressor binding protein,Trp repressor-binding protein,NAD(P)H:quinone oxidoreductase,NAD(P)H:quinone oxidoreductase%2C type IV,NADPH-de [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 30532 30699 . + 0 ID=22222_2#22_04086;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_006087756.1,protein motif:Pfam:PF10685.3;locus_tag=22222_2#22_04086;product=Conidiation-specific protein 10,Stress-induced bacterial acidophilic repeat motif;protein_id=gnl|SC|22222_2#22_04086
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 30836 31474 . + 0 ID=22222_2#22_04087;gene=rutR;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729849.1,similar to AA sequence:UniProtKB:P0ACU2,protein motif:CLUSTERS:PRK15008,protein motif:TIGRFAMs:TIGR03613,protein motif:Pfam:PF08362.5;locus_tag=22222_2#22_04087;product=transcriptional regulator,Rut operon repressor,HTH-type transcriptional regulator RutR,pyrimidine utilization regulatory protein R,YcdC-like [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 31471 31866 . - 0 ID=22222_2#22_04088;inference=ab initio prediction:Prodigal:2.60,protein motif:Cdd:COG3755,protein motif:Pfam:PF07007.6;locus_tag=22222_2#22_04088;product=Uncharacterized protein conserved in bacteria,Protein of unknown function (DUF1311);protein_id=gnl|SC|22222_2#22_04088
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 31925 35887 . - 0 ID=22222_2#22_04089;gene=putA;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002243116.1,similar to AA sequence:UniProtKB:P09546,protein motif:CLUSTERS:PRK11809,protein motif:Cdd:COG4230,protein motif:TIGRFAMs:TIGR01238,protein motif:Pfam:PF01619.12;locus_tag=22222_2#22_04089;product=trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase,Bifunctional p [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 36309 37817 . + 0 ID=22222_2#22_04090;gene=putP;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002145994.1,similar to AA sequence:UniProtKB:P07117,protein motif:CLUSTERS:PRK15419,protein motif:Cdd:COG4145,protein motif:TIGRFAMs:TIGR02121,protein motif:Pfam:PF00474.11;locus_tag=22222_2#22_04090;product=sodium/proline symporter,Propionate transporter,proline:sodium symporter PutP,Na+/panthothenate symporter,sodium/p [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 38435 38731 . + 0 ID=22222_2#22_04091;inference=ab initio prediction:Prodigal:2.60;locus_tag=22222_2#22_04091;product=hypothetical protein;protein_id=gnl|SC|22222_2#22_04091
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 38710 39498 . + 0 ID=22222_2#22_04092;gene=phoH;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729855.1,similar to AA sequence:UniProtKB:P0A9K1,protein motif:CLUSTERS:PRK10536,protein motif:Cdd:COG1875,protein motif:Pfam:PF02562.10;locus_tag=22222_2#22_04092;product=phosphate starvation-inducible protein PsiH,Phosphate starvation-inducible protein psiH,hypothetical protein,Predicted ATPase related to phosphate [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 39604 40485 . - 0 ID=22222_2#22_04093;gene=ybbH_2;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_001570898.1,similar to AA sequence:UniProtKB:Q45581,protein motif:CLUSTERS:PRK11337,protein motif:Cdd:COG2222,protein motif:TIGRFAMs:TIGR03127,protein motif:Pfam:PF01418.11;locus_tag=22222_2#22_04093;product=putative transcriptional regulator,Uncharacterized HTH-type transcriptional regulator ybbH,DNA-binding transcrip [...]
+ERS222222|SC|contig000020 Infernal:1.1 ncRNA 40486 40770 . + 0 ID=22222_2#22_04094;inference=COORDINATES:profile:Infernal:1.1;locus_tag=22222_2#22_04094;product=STnc500
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 40771 41673 . - 0 ID=22222_2#22_04095;gene=yidK;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002215057.1,similar to AA sequence:UniProtKB:P31448,protein motif:CLUSTERS:PRK10484,protein motif:Cdd:COG4146,protein motif:TIGRFAMs:TIGR00813,protein motif:Pfam:PF00474.11;locus_tag=22222_2#22_04095;product=sodium-glucose/galactose cotransporter,Uncharacterized symporter yidK,putative transporter,Predicted symporter,tra [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 41741 42268 . - 0 ID=22222_2#22_04096;gene=sglT;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002215057.1,similar to AA sequence:UniProtKB:P96169,protein motif:CLUSTERS:PRK10484,protein motif:Cdd:COG4146,protein motif:TIGRFAMs:TIGR00813,protein motif:Pfam:PF00474.11;locus_tag=22222_2#22_04096;product=sodium-glucose/galactose cotransporter,Na(+)/glucose symporter,putative transporter,Predicted symporter,transporte [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 42605 43285 . - 0 ID=22222_2#22_04097;eC_number=5.1.3.9;gene=nanE;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_001570896.2,similar to AA sequence:UniProtKB:P60668,protein motif:CLUSTERS:PRK01130,protein motif:Pfam:PF04131.8;locus_tag=22222_2#22_04097;product=N-acetylmannosamine-6-phosphate 2-epimerase,Putative N-acetylmannosamine-6-phosphate 2-epimerase,N-acetylmannosamine-6-phosphate 2-epimerase,Putative N-acet [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 43804 44946 . + 0 ID=22222_2#22_04098;eC_number=5.1.3.24;gene=nanM;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_001570895.1,similar to AA sequence:UniProtKB:P44544,protein motif:CLUSTERS:PRK14131,protein motif:TIGRFAMs:TIGR03547,protein motif:Pfam:PF01344.19;locus_tag=22222_2#22_04098;product=N-acetylneuraminic acid mutarotase,N-acetylneuraminate epimerase precursor,N-acetylneuraminic acid mutarotase,mutatrotase [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 44992 45684 . + 0 ID=22222_2#22_04099;gene=yiiy;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_216068.1,similar to AA sequence:UniProtKB:Q934G3,protein motif:CLUSTERS:PRK09980,protein motif:Cdd:COG3203,protein motif:Pfam:PF06178.7;locus_tag=22222_2#22_04099;product=outer membrane protein,Oligogalacturonate-specific porin kdgM precursor,outer membrane porin L,Outer membrane protein (porin),Oligogalacturonate-specif [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 45967 47247 . + 0 ID=22222_2#22_04100;gene=nanT_3;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_001570893.1,similar to AA sequence:UniProtKB:P41036,protein motif:CLUSTERS:PRK12307,protein motif:Cdd:COG2814,protein motif:TIGRFAMs:TIGR00891,protein motif:Pfam:PF00083.18;locus_tag=22222_2#22_04100;product=putative sialic acid transporter,Sialic acid permease,putative sialic acid transporter,Arabinose efflux permease [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 47261 48364 . + 0 ID=22222_2#22_04101;eC_number=1.1.1.292;gene=yjhC;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_216069.1,similar to AA sequence:UniProtKB:Q2I8V6,protein motif:CLUSTERS:PRK11579,protein motif:Pfam:PF01408.16;locus_tag=22222_2#22_04101;product=dehydrogenase-like protein,1%2C5-anhydro-D-fructose reductase,putative oxidoreductase,Oxidoreductase family%2C NAD-binding Rossmann fold;protein_id=gnl|SC|2 [...]
+ERS222222|SC|contig000020 Aragorn:1.2.36 tRNA 48701 48788 . - 0 ID=22222_2#22_04102;inference=COORDINATES:profile:Aragorn:1.2.36;locus_tag=22222_2#22_04102;product=tRNA-Ser(gga)
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 49024 49962 . + 0 ID=22222_2#22_04103;eC_number=1.1.1.79;gene=ghrA;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729856.1,similar to AA sequence:UniProtKB:Q8ZQ30,protein motif:CLUSTERS:PRK15469,protein motif:Cdd:COG1932,protein motif:TIGRFAMs:TIGR01327,protein motif:Pfam:PF02826.13;locus_tag=22222_2#22_04103;product=2-hydroxyacid dehydrogenase,Glyoxylate/hydroxypyruvate reductase A,bifunctional glyoxylate/hydr [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 50047 50784 . + 0 ID=22222_2#22_04104;eC_number=3.1.3.-;gene=ycdX;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_001570887.1,similar to AA sequence:UniProtKB:P75914,protein motif:CLUSTERS:PRK09248,protein motif:Cdd:COG1387,protein motif:TIGRFAMs:TIGR01856,protein motif:Pfam:PF02811.13;locus_tag=22222_2#22_04104;product=putative hydrolase,Probable phosphatase YcdX,putative hydrolase,Histidinol phosphatase and relat [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 50808 51362 . + 0 ID=22222_2#22_04105;gene=ycdY;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002146908.1,similar to AA sequence:UniProtKB:P75915,protein motif:CLUSTERS:PRK11621,protein motif:Cdd:COG3381,protein motif:Pfam:PF02613.9;locus_tag=22222_2#22_04105;product=chaperone%2C TorD family,Chaperone protein YcdY,twin-argninine leader-binding protein DmsD,Uncharacterized component of anaerobic dehydrogenases,Nit [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 51451 51945 . + 0 ID=22222_2#22_04106;gene=ycdZ;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P75916,protein motif:Pfam:PF06496.5;locus_tag=22222_2#22_04106;product=Inner membrane protein ycdZ,Protein of unknown function (DUF1097);protein_id=gnl|SC|22222_2#22_04106
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 51983 52816 . - 0 ID=22222_2#22_04107;gene=csgG;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729860.1,protein motif:CLUSTERS:PRK15184,protein motif:Pfam:PF03783.8;locus_tag=22222_2#22_04107;product=assembly/transport component in curli production,curli production assembly/transport protein CsgG,Curli production assembly/transport component CsgG;protein_id=gnl|SC|22222_2#22_04107
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 52843 53259 . - 0 ID=22222_2#22_04108;gene=csgF;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729861.1,protein motif:CLUSTERS:PRK10050,protein motif:Pfam:PF10614.3;locus_tag=22222_2#22_04108;product=assembly/transport component in curli production,curli assembly protein CsgF,Curli production assembly/transport component CsgF;protein_id=gnl|SC|22222_2#22_04108
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 53286 53681 . - 0 ID=22222_2#22_04109;gene=csgE;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729862.1,protein motif:CLUSTERS:PRK10386,protein motif:Pfam:PF10627.3;locus_tag=22222_2#22_04109;product=assembly/transport component in curli production,curli assembly protein CsgE,Curli assembly protein CsgE;protein_id=gnl|SC|22222_2#22_04109
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 53710 54336 . - 0 ID=22222_2#22_04110;gene=csgD;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729863.1,similar to AA sequence:UniProtKB:P52106,protein motif:CLUSTERS:PRK10100,protein motif:Cdd:COG2909,protein motif:TIGRFAMs:TIGR03020,protein motif:Pfam:PF00196.13;locus_tag=22222_2#22_04110;product=regulatory protein,CsgBAC operon transcriptional regulatory protein,DNA-binding transcriptional regulator CsgD,ATP [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 55092 55547 . + 0 ID=22222_2#22_04111;gene=csgB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729864.1,similar to AA sequence:UniProtKB:P0A1E9,protein motif:CLUSTERS:PRK10101,protein motif:Pfam:PF07012.6;locus_tag=22222_2#22_04111;product=nucleation component of curlin monomers,Fimbrin SEF17 minor subunit,curlin minor subunit CsgB,Curlin associated repeat;protein_id=gnl|SC|22222_2#22_04111
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 55589 56044 . + 0 ID=22222_2#22_04112;gene=csgA;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729865.1,similar to AA sequence:UniProtKB:P0A1E7,protein motif:CLUSTERS:PRK10051,protein motif:Pfam:PF07012.6;locus_tag=22222_2#22_04112;product=major curlin subunit,Fimbrin SEF17,major curlin subunit,Curlin associated repeat;protein_id=gnl|SC|22222_2#22_04112
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 56106 56432 . + 0 ID=22222_2#22_04113;gene=csgC;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_007470940.1,similar to AA sequence:UniProtKB:P0A1Z9,protein motif:CLUSTERS:PRK10102,protein motif:Pfam:PF10610.3;locus_tag=22222_2#22_04113;product=curli assembly protein CsgC,Curli assembly protein CsgC precursor,curli assembly protein CsgC,Thin aggregative fimbriae synthesis protein;protein_id=gnl|SC|22222_2#22_04113
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 56564 56884 . + 0 ID=22222_2#22_04114;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_006087410.1;locus_tag=22222_2#22_04114;product=Fimbrial protein;protein_id=gnl|SC|22222_2#22_04114
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 56972 57511 . + 0 ID=22222_2#22_04115;eC_number=3.5.1.-;gene=ymdB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_006087411.1,similar to AA sequence:UniProtKB:P0A8D6,protein motif:CLUSTERS:PRK00431,protein motif:Pfam:PF01661.15;locus_tag=22222_2#22_04115;product=Macro domain%2C possibly ADP-ribose binding module,O-acetyl-ADP-ribose deacetylase,RNase III inhibitor,Macro domain;protein_id=gnl|SC|22222_2#22_04115
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 57450 58934 . + 0 ID=22222_2#22_04116;eC_number=2.7.8.-;gene=ybhO_2;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_001570877.2,similar to AA sequence:UniProtKB:P0AA84,protein motif:CLUSTERS:PRK01642,protein motif:TIGRFAMs:TIGR04265;locus_tag=22222_2#22_04116;product=phospholipase,Putative cardiolipin synthase YbhO,cardiolipin synthetase,cardiolipin synthase;protein_id=gnl|SC|22222_2#22_04116
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 58951 60105 . - 0 ID=22222_2#22_04117;eC_number=2.1.-.-;gene=mdoC;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_001570876.1,similar to AA sequence:UniProtKB:P75920,protein motif:CLUSTERS:PRK03854,protein motif:Cdd:COG3274,protein motif:Pfam:PF01757.16;locus_tag=22222_2#22_04117;product=glucans biosynthesis protein,Glucans biosynthesis protein C,glucans biosynthesis protein,Uncharacterized protein conserved in bac [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 60359 61912 . + 0 ID=22222_2#22_04118;gene=mdoG;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_001570875.1,similar to AA sequence:UniProtKB:P33136,protein motif:CLUSTERS:PRK13274,protein motif:Cdd:COG3131,protein motif:Pfam:PF04349.6;locus_tag=22222_2#22_04118;product=glucan biosynthesis protein G,Glucans biosynthesis protein G precursor,glucan biosynthesis protein G,Periplasmic glucans biosynthesis protein,Peripl [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 61905 64448 . + 0 ID=22222_2#22_04119;eC_number=2.4.1.-;gene=mdoH;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_216085.1,similar to AA sequence:UniProtKB:P62517,protein motif:CLUSTERS:PRK05454,protein motif:Pfam:PF00535.20;locus_tag=22222_2#22_04119;product=glucosyltransferase MdoH,Glucans biosynthesis glucosyltransferase H,glucosyltransferase MdoH,Glycosyl transferase family 2;protein_id=gnl|SC|22222_2#22_04119
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 64522 64749 . + 0 ID=22222_2#22_04120;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729872.1,protein motif:CLUSTERS:PRK10175,protein motif:Cdd:COG5645,protein motif:Pfam:PF07119.6;locus_tag=22222_2#22_04120;product=lipoprotein,lipoprotein,Predicted periplasmic lipoprotein,Protein of unknown function (DUF1375);protein_id=gnl|SC|22222_2#22_04120
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 64750 65124 . - 0 ID=22222_2#22_04121;gene=msyB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729873.1,protein motif:CLUSTERS:PRK11467;locus_tag=22222_2#22_04121;product=acidic protein MsyB,secY/secA suppressor protein;protein_id=gnl|SC|22222_2#22_04121
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 65206 66420 . - 0 ID=22222_2#22_04122;gene=yceE;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729874.1,similar to AA sequence:UniProtKB:O31762,protein motif:CLUSTERS:PRK09874,protein motif:Cdd:COG2814,protein motif:TIGRFAMs:TIGR00880,protein motif:Pfam:PF07690.10;locus_tag=22222_2#22_04122;product=membrane transport protein,Bacillibactin exporter,drug efflux system protein MdtG,Arabinose efflux permease,multid [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 66575 67495 . - 0 ID=22222_2#22_04123;eC_number=2.3.1.-;gene=htrB_2;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729875.1,similar to AA sequence:UniProtKB:P0ACV0,protein motif:CLUSTERS:PRK06860,protein motif:Cdd:COG1560,protein motif:TIGRFAMs:TIGR02207,protein motif:Pfam:PF03279.7;locus_tag=22222_2#22_04123;product=lipid A biosynthesis lauroyl acyltransferase,Lipid A biosynthesis lauroyl acyltransferase,lipid [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 67715 68767 . + 0 ID=22222_2#22_04124;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_006087420.1,protein motif:CLUSTERS:PRK00142,protein motif:Cdd:COG2210,protein motif:Pfam:PF00581.14;locus_tag=22222_2#22_04124;product=Rhodanese-like sulfurtransferase,putative rhodanese-related sulfurtransferase,Uncharacterized conserved protein,Rhodanese-like domain;protein_id=gnl|SC|22222_2#22_04124
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 68819 69394 . - 0 ID=22222_2#22_04125;gene=yceI_2;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_006087865.1,similar to AA sequence:UniProtKB:P0A8X2,protein motif:CLUSTERS:PRK03757,protein motif:Cdd:COG2353,protein motif:Pfam:PF04264.7;locus_tag=22222_2#22_04125;product=YceI protein,hypothetical protein,hypothetical protein,Uncharacterized conserved protein,YceI-like domain;protein_id=gnl|SC|22222_2#22_04125
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 69391 69795 . - 0 ID=22222_2#22_04126;gene=yceJ;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_005212184.1,similar to AA sequence:UniProtKB:P75925,protein motif:CLUSTERS:PRK11513,protein motif:Pfam:PF00033.13;locus_tag=22222_2#22_04126;product=cytochrome b561-like protein 2,Cytochrome b561 homolog 2,cytochrome b561,Cytochrome b(N-terminal)/b6/petB;protein_id=gnl|SC|22222_2#22_04126
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 70226 70339 . - 0 ID=22222_2#22_04127;gene=yceO;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_216094.1,similar to AA sequence:UniProtKB:P64442,protein motif:Pfam:PF10968.2;locus_tag=22222_2#22_04127;product=inner membrane protein,hypothetical protein,Protein of unknown function (DUF2770);protein_id=gnl|SC|22222_2#22_04127
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 70380 71498 . - 0 ID=22222_2#22_04128;eC_number=1.5.3.1,1.5.3.-;gene=solA;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729880.1,similar to AA sequence:UniProtKB:P40874,protein motif:CLUSTERS:PRK11259,protein motif:Cdd:COG4121,protein motif:TIGRFAMs:TIGR01377,protein motif:Pfam:PF01266.18;locus_tag=22222_2#22_04128;product=sarcosine oxidase,N-methyl-L-tryptophan oxidase,N-methyltryptophan oxidase,Uncharacteriz [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 71611 71865 . - 0 ID=22222_2#22_04129;gene=bssS;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_001570863.1,protein motif:CLUSTERS:PRK12301;locus_tag=22222_2#22_04129;product=biofilm formation regulatory protein BssS,biofilm formation regulatory protein BssS;protein_id=gnl|SC|22222_2#22_04129
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 72155 72418 . - 0 ID=22222_2#22_04130;gene=dinI_3;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729882.1,similar to AA sequence:UniProtKB:P0ABR1,protein motif:CLUSTERS:PRK10597,protein motif:Pfam:PF06183.7;locus_tag=22222_2#22_04130;product=damage-inducible protein,DNA-damage-inducible protein I,DNA damage-inducible protein I,DinI-like family;protein_id=gnl|SC|22222_2#22_04130
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 72492 73538 . - 0 ID=22222_2#22_04131;eC_number=3.5.2.3,3.5.2.3;gene=pyrC;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729883.1,similar to AA sequence:UniProtKB:P06204,protein motif:CLUSTERS:PRK05451,protein motif:Cdd:COG0418,protein motif:TIGRFAMs:TIGR00856,protein motif:Pfam:PF01979.14;locus_tag=22222_2#22_04131;product=dihydroorotase,Dihydroorotase,dihydroorotase,Dihydroorotase,dihydroorotase%2C homodimeri [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 73642 74268 . - 0 ID=22222_2#22_04132;gene=yceB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_007470922.1,similar to AA sequence:UniProtKB:P0AB26,protein motif:CLUSTERS:PRK10598,protein motif:Pfam:PF07273.6;locus_tag=22222_2#22_04132;product=lipoprotein,Uncharacterized lipoprotein yceB precursor,lipoprotein,Protein of unknown function (DUF1439);protein_id=gnl|SC|22222_2#22_04132
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 74326 74973 . - 0 ID=22222_2#22_04133;gene=grxB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729885.1,similar to AA sequence:UniProtKB:P0AC59,protein motif:CLUSTERS:PRK10387,protein motif:TIGRFAMs:TIGR02182,protein motif:Pfam:PF04399.7;locus_tag=22222_2#22_04133;product=glutaredoxin,Glutaredoxin-2,glutaredoxin 2,glutaredoxin%2C GrxB family,Glutaredoxin 2%2C C terminal domain;protein_id=gnl|SC|22222_2#22_04133
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 75037 76245 . - 0 ID=22222_2#22_04134;gene=mdtH;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_001570858.1,similar to AA sequence:UniProtKB:P69367,protein motif:CLUSTERS:PRK11646,protein motif:Cdd:COG2814,protein motif:TIGRFAMs:TIGR00880,protein motif:Pfam:PF07690.10;locus_tag=22222_2#22_04134;product=multidrug resistance protein MdtH,Multidrug resistance protein MdtH,multidrug resistance protein MdtH,Arabinose ef [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 76482 77066 . + 0 ID=22222_2#22_04135;eC_number=2.3.1.-;gene=rimJ;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729887.1,similar to AA sequence:UniProtKB:P96579,protein motif:CLUSTERS:PRK10809,protein motif:TIGRFAMs:TIGR03585,protein motif:Pfam:PF00583.18;locus_tag=22222_2#22_04135;product=ribosomal-protein-alanine acetyltransferase,Putative ribosomal N-acetyltransferase YdaF,ribosomal-protein-S5-alanine N-ace [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 77102 77749 . + 0 ID=22222_2#22_04136;gene=yceH;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P29217,protein motif:CLUSTERS:PRK11239,protein motif:Cdd:COG3132,protein motif:Pfam:PF04337.6;locus_tag=22222_2#22_04136;product=G20.3,hypothetical protein,Uncharacterized protein conserved in bacteria,Protein of unknown function%2C DUF480;protein_id=gnl|SC|22222_2#22_04136
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 77751 78674 . + 0 ID=22222_2#22_04137;gene=mviM;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729889.1,similar to AA sequence:UniProtKB:P75931,protein motif:CLUSTERS:PRK11579,protein motif:Cdd:COG3132,protein motif:Pfam:PF01408.16;locus_tag=22222_2#22_04137;product=virulence factor MviM,Virulence factor mviM homolog,putative oxidoreductase,Uncharacterized protein conserved in bacteria,Oxidoreductase family%2C [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 78939 80513 . + 0 ID=22222_2#22_04138;gene=mviN;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002146873.1,similar to AA sequence:UniProtKB:P37169,protein motif:TIGRFAMs:TIGR01695,protein motif:Pfam:PF03023.8;locus_tag=22222_2#22_04138;product=integral membrane protein MviN,hypothetical protein,integral membrane protein MviN,MviN-like protein;protein_id=gnl|SC|22222_2#22_04138
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 80595 81017 . - 0 ID=22222_2#22_04139;gene=flgN;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729891.1,protein motif:CLUSTERS:PRK15459,protein motif:Pfam:PF05130.6;locus_tag=22222_2#22_04139;product=flagella synthesis protein FlgN,flagella synthesis chaperone protein FlgN,FlgN protein;protein_id=gnl|SC|22222_2#22_04139
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 81022 81315 . - 0 ID=22222_2#22_04140;gene=flgM;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729892.1,similar to AA sequence:UniProtKB:P26477,protein motif:CLUSTERS:PRK10810,protein motif:TIGRFAMs:TIGR03824,protein motif:Pfam:PF04316.7;locus_tag=22222_2#22_04140;product=negative regulator of flagellin synthesis (anti-sigma factor),Anti-sigma-28 factor,anti-sigma28 factor FlgM,flagellar biosynthesis anti-sigma [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 81407 82066 . - 0 ID=22222_2#22_04141;gene=flgA;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729893.1,protein motif:CLUSTERS:PRK07018,protein motif:TIGRFAMs:TIGR03170,protein motif:Pfam:PF08666.6;locus_tag=22222_2#22_04141;product=flagellar basal body P-ring protein FlgA,flagellar basal body P-ring biosynthesis protein FlgA,flagella basal body P-ring formation protein FlgA,SAF domain;protein_id=gnl|SC|22222_2 [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 82223 82639 . + 0 ID=22222_2#22_04142;gene=flgB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729894.1,similar to AA sequence:UniProtKB:P16437,protein motif:CLUSTERS:PRK05680,protein motif:Cdd:COG1815,protein motif:TIGRFAMs:TIGR01396,protein motif:Pfam:PF00460.14;locus_tag=22222_2#22_04142;product=flagellar basal-body rod protein FlgB,Putative proximal rod protein,flagellar basal body rod protein FlgB,Flagella [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 82643 83047 . + 0 ID=22222_2#22_04143;gene=flgC;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729895.1,similar to AA sequence:UniProtKB:P0A1I7,protein motif:CLUSTERS:PRK05681,protein motif:Cdd:COG4786,protein motif:TIGRFAMs:TIGR01395,protein motif:Pfam:PF06429.7;locus_tag=22222_2#22_04143;product=flagellar basal-body rod protein FlgC,Putative proximal rod protein,flagellar basal body rod protein FlgC,Flagellar [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 83059 83757 . + 0 ID=22222_2#22_04144;gene=flgD;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729896.1,similar to AA sequence:UniProtKB:P0A1I9,protein motif:CLUSTERS:PRK06655,protein motif:Cdd:COG1843,protein motif:Pfam:PF03963.8;locus_tag=22222_2#22_04144;product=flagellar hook formation protein FlgD,Basal-body rod modification protein flgD,flagellar basal body rod modification protein,Flagellar hook capping [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 83784 84995 . + 0 ID=22222_2#22_04145;gene=flgE;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_002146866.1,similar to AA sequence:UniProtKB:P0A1J1,protein motif:CLUSTERS:PRK05682,protein motif:Cdd:COG1749,protein motif:TIGRFAMs:TIGR03506,protein motif:Pfam:PF07559.8;locus_tag=22222_2#22_04145;product=flagellar hook protein FlgE,Flagellar hook protein flgE,flagellar hook protein FlgE,Flagellar hook protein FlgE,fla [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 85016 85771 . + 0 ID=22222_2#22_04146;gene=flgF;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729898.1,similar to AA sequence:UniProtKB:P16323,protein motif:CLUSTERS:PRK12640,protein motif:Cdd:COG4787,protein motif:TIGRFAMs:TIGR03506,protein motif:Pfam:PF06429.7;locus_tag=22222_2#22_04146;product=flagellar basal-body rod protein FlgF,Putative proximal rod protein,flagellar basal body rod protein FlgF,Flagellar [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 85785 86567 . + 0 ID=22222_2#22_04147;gene=flgG;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729899.1,similar to AA sequence:UniProtKB:P0A1J3,protein motif:CLUSTERS:PRK12694,protein motif:Cdd:COG4786,protein motif:TIGRFAMs:TIGR02488,protein motif:Pfam:PF06429.7;locus_tag=22222_2#22_04147;product=flagellar basal-body rod protein FlgG (distal rod protein),Distal rod protein,flagellar basal body rod protein FlgG [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 86655 87320 . + 0 ID=22222_2#22_04148;gene=flgH;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729900.1,similar to AA sequence:UniProtKB:Q9PPM0,protein motif:CLUSTERS:PRK00249,protein motif:Pfam:PF02107.10;locus_tag=22222_2#22_04148;product=flagellar L-ring protein,Basal body L-ring protein,flagellar basal body L-ring protein,Flagellar L-ring protein;protein_id=gnl|SC|22222_2#22_04148
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 87332 88429 . + 0 ID=22222_2#22_04149;gene=flgI;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729901.1,similar to AA sequence:UniProtKB:Q9PMJ8,protein motif:CLUSTERS:PRK05303,protein motif:Cdd:COG1706,protein motif:Pfam:PF02119.10;locus_tag=22222_2#22_04149;product=flagellar P-ring protein,Basal body P-ring protein,flagellar basal body P-ring protein,Flagellar basal-body P-ring protein,Flagellar P-ring protein [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 88429 89379 . + 0 ID=22222_2#22_04150;eC_number=3.2.1.-;gene=flgJ;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729902.1,similar to AA sequence:UniProtKB:P15931,protein motif:CLUSTERS:PRK05684,protein motif:Cdd:COG3951,protein motif:TIGRFAMs:TIGR02541,protein motif:Pfam:PF01832.14;locus_tag=22222_2#22_04150;product=flagellar protein FlgJ,Peptidoglycan hydrolase flgJ,flagellar rod assembly protein/muramidase Fl [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 89444 91105 . + 0 ID=22222_2#22_04151;gene=flgK;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729903.1,similar to AA sequence:UniProtKB:P0A1J5,protein motif:CLUSTERS:PRK08147,protein motif:Cdd:COG1749,protein motif:TIGRFAMs:TIGR02492,protein motif:Pfam:PF06429.7;locus_tag=22222_2#22_04151;product=flagellar hook-associated protein 1,Flagellar hook-associated protein 1,flagellar hook-associated protein FlgK,Flag [...]
+ERS222222|SC|contig000020 Prodigal:2.60 CDS 91120 92073 . + 0 ID=22222_2#22_04152;gene=flgL;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_004729904.1,similar to AA sequence:UniProtKB:P16326,protein motif:CLUSTERS:PRK08027,protein motif:Cdd:COG3951,protein motif:TIGRFAMs:TIGR02550,protein motif:Pfam:PF00669.14;locus_tag=22222_2#22_04152;product=flagellar hook-associated protein 3,Hook-filament junction protein,flagellar hook-associated protein FlgL,Rod bind [...]
+ERS222222|SC|contig000020 Infernal:1.1 ncRNA 92162 92255 . + 0 ID=22222_2#22_04153;inference=COORDINATES:profile:Infernal:1.1;locus_tag=22222_2#22_04153;product=STnc490k
+##FASTA
+>ERS222222|SC|contig000020
+TATCCGGGCAGCCCGTTTACGGGCCGTAAGTAACGAAGTTTGATGCAAATGTCAGATCGT
+ATGCGCCTGTTAGGGCGCGGCTGGTAAGAGAGACTTACAGGCGCATCAGAAAAACCTCCG
+GCTATGCCGGAGGATATTTATTTTTTGGGCGCATAGAATATAGTTAGAAAATACTGCTAG
+AACATTTCCCGAAAAAACGGACTACGTGGGTTATTAGTTTCTTTTCGTTTCTTGATGTGT
+CTATTTATTGAAGATGTAGACCATTCTGGGAGATGAAGGATGCCCCATCTCTTTCAGAAT
+AATGTTGGTATATTCGACAACAGGGCCTCTTGAATGATTTTCTTCTTTATCCTGAAGATG
+GGTCAGTGCATGTACAACTTCATGAGTAAATGAACGTTTTGTGTCAAAAAGTTGTCTTCC
+TTCGTTACTTTCATAATGTTCGGTATATGAATAATCAGAATCGTCCAGATTGAGACAAAT
+AACTTTCCTGCCTTCTGAAAGTTTGAAGTGTTACTGAGCCACGGTAGTTTCAAAGGCTTC
+GCCTGCCCCCGGTAGCCAGCGCTGCTCCACATAATGTAGTTCTTTTTCATATGCGTAATT
+CATCAGTCTGCGGAATGTTTCGCTTTGGGTATACGCATTTTGAAGTACGGAGGATAGTTC
+ATCGTAGCATTCGTCATAAGTGTCGTCATCAAATTCTGTATCAGGGTCTATTCCACCCGC
+GCCTGAGATAAGGTACTCCACCACACACTCTGACTCCAGACGGAATTCACTGTTTATGGC
+AAGGCTGTCATGAGCAAGGCGTAGCCGTGAGGAGTTTGGTGCATGTTCGGGAATATCGGG
+GAAAACAGGTGTATCTGCGGTATTTAATCCATATGTGGATACTCCGCTTTGAGGTATTAA
+TCTGTAGGTGACCGGAAGCATAATTTCTTATTACCTGACTGCAATTATGAATTATTTAAA
+TTAAACAATAATAGTGTTTTTAGTTAATGTGCAACATACAGATAACGCTATGATTCAGGC
+AAAACCAACAAGTAATACGCTGAAAATGTTATATATAATGAAGCTTAGGGGCGGGGTTTG
+TTTAATAAAACAAGGAGGGCTTCTGTTTGAATACTTCTTGTTTATAAAATCCCTTTATCT
+CGACTAAAATATTGGATGGGGGAAAAGCGTTTAATCATTGTAATCCGGGAGTGGAGTAGG
+GGTATGTTGACTACCTGTCAGATCGGCTCCTGATAATGCTTTCGCTAAAGTTAGAGCTAT
+CTTATCTAATTTTGCACCATTTAGTTTGGTGTAAGTTAAGTCTGAGCCGAATAGAATTGC
+AGCGGTTAAGTTTACACCGGACATGTTAGCGCAAGTCAGGTCTGCGTGAGTCAGGTTTGC
+TTTAGTCATGTTTGAACCCATTAGATTTACAGAGTGTAGATTTGCACAACACAAATTTGC
+ACCGACTAAATTTACATTAGATAGATTTGTTTAACGGAAATCTGCATTAGAAGCATCTAT
+GTCTGACAAATCTTCTCCCTGGAAATCTTTATAAGCTAGGTTTACTCCGCGCAGGTTCAG
+AAAACCATCCTCGGTTATAAGTGAATCAGGCTATTGTATATTATGTTTACTCATCAGTTT
+TAACATTCGACATACATTCCAAAATCTCTCACAATCAACTTTATCCGTTACAGTTTTTCC
+ATTTTTGTTCACTTCAATAGTGACCATGGGATACGTATTTTCGGATGCTGCTCCACATGA
+CAGACATATAGTACACCCGTTGACATCCTCCAAAAATATTTTATTACCATCGAAGAAAGC
+ATCTTTATTTACATATAATAATGATGTGGTCAATTTTCCAATTACCTCCCAAAAGCATCT
+TTCATTGCTTCTTCTTACTCCACCACAGGTAAAAAAATTGACAAACCATTCCAGTATACC
+GCGTGGTGAAGTTGCACTTTTCATTGCTTCTTACGTACCGGTACCGGCCGCATGCAAATA
+TCTTAATATATTTTCTGGGGACGCGTTAGTTAATGGCATTTTGATTCCTTCTTATGGAAG
+TGAGTCGATTCCTTATAGGTGTGAGTCAAGTCACATTTATACAAGGAATAATAAAAAAAG
+ATATAAGGTGATTTTTGTATTTAGAGCTTTGGATGAGTATGAGTAGGTGTCTGGCATCTG
+ACAAGAGGCGATGATATCTGCCATAACGGTGAAGCAGAAGTAATATCACCCGTGAATAAT
+AAGATTATCCTTGCTATTGACTTCCTTCATTTACAGCATAGCTTACGCCTCATCATCATT
+GAATAAACAATTAAGTTTGTTGAGCGAAAATTAACTTAAAGAAAAAATAATAAGCTTTAA
+TATTTTTTGCAGCATTTCAACTTATAGCAGAAAAAATGTGCGTAGATGGCGTAAAAACCT
+GATGAGCAGGAATACTTACACACTAAAAATGCACCCGCAAACAGAGCAAAATGAGAAAGA
+GGAACGTTTGCCCTTTACATTTCCACCAAAGAATCTGGTTTTGTCTCTTGTAAAGGGCAT
+ACGTATCGCGTTTTATCTCATTAAGAAAGTATATTGACGTATTAAATTATGCATAATGCT
+CTTTCAATTGCTTCACGTTTGAAATGAATAATACAAAACCAGTGAGCGCCTCTTCTTCGG
+TACTGGTTTGCGGCAAGCGATAAAGCGCCACTAAAGCAGTATTGTCTGCATCAGCGCCGA
+TAGTGACGGCGCTGGCGTAGTTAAGACGTAAAAAATGCTGCAAAGTCAGAGTGTCGTCAG
+GCAGTGGCATAAAGGGACAGCACATTTCCAGTATATGATCGGATTCATTAAAATAAACCT
+GTATCCCATCATCAATGATAAGCAGTGGCTCAACTTCTGGCGCATCCAGGCCTAACGCGT
+CATATAAACGATTTAATAGACTTTCCATATAGATACCTCAAGACTCAAGATGTGATTAAT
+GAAGAAATACCTTTTACTGACTGCCAAATATTATCATCCCCAACTCGTTTTTGATAGGAA
+AGATTGAGCACCTCTGGCGATAAATTTTTCATTACTTTGTTTCCCGCCCCGCCCGTATTT
+TGTTTCTGAATCTCCAGGTTACCGCTATTCAGTAATACTTTTTGGAAAATTTTCTGTCCA
+CCGCTATCCGGAAGACTACCAGGCGCACTTAACATATGGGTCTGATGGAAAGAAATGAGC
+TCTCGCTTGATTTCTGAATCCATCATCCCTGTACGATCTTTGCCGCTTTTACAATTCCAG
+GCGGGCACCGCGTCAATTTCATGGGCTAACATGGCAAGGCGTTGTGCGAGTTTATAGGGT
+TCGCCGCCATCTTTATGATGTTGGTTATTTTTCCAGATATCCTTAATCTGGCGCGCTAAT
+GTATTGACGACCTCATAATTATCCGGGTATTGCGCCAGCCATTCGCCAACCCAGCCACCT
+GGTCTGGCTTCAGGGCGTAAATCATTGCCTAATAACTGATGTAGCGCTTCGGCATTATAG
+CTATCTGATGCTTTAAGGCCAAAGCCGAGCTTGAGCGCCAGCTCATTAACACCCACATTA
+AATGCGGCGACGTCCGGTTTTATTTTTACCGTCTGTAGATCGCCATCTTTATTGCGGATT
+TTTAAATGAATCATTTTTCCCGGCTGGGTCAACGATTGCCATGCGCGCATTTGATCCTCG
+ACCATAGTTCCCTCTTTGCCGAAAATATTCGACGCGGTGAGTAACCCGACGGATACCAGT
+TTCAGGCTTACCGCTTCGCCCTCTAAGGCTCTGTTAAGCAACTCAGGTTTACTAAAAAGT
+GCCGCAGCTAATACTTCTTTGGCTTTGTTTTCAGCGCCGGCCTGACGCAGAAGCGGATCT
+TTTTCATGATAGGGGGAAAGCACACCATGACGTATCCCGCAAAAAAGCGTTTTATCTTTA
+CCGTCCTCATGCACACTCACCGTGGACATCCACAAATTATTGGCGTGATGAATATTCTTG
+GTATCCCAACTGCATACGCCCTTTCCCTCATAAGCACTGGGAAAGATATCTTTTGCGCCG
+ATTTTCATCTCTGCGGCAGGGAGCTGCGTGTTGGTATAGTGATGCCCGTTATGCGTGAGT
+GTATTTTTTATGGTTTGCCAGGGCTGGTTATTGAGCTGCTTGACCTGAGCATCTCTAAAC
+GCTACTGCCGCAAAGCGATGAGCTTCTTTTGCAGGTAAGCCATTTTGCTGCTGAGTGCGT
+GCTGCAATAAGTTCGATAAGATTTTTCTTCAATGCTTTTGCCGCAGCTTCTTCTTGTTTT
+GTTGCTGGCCGGTCCGCTTTAACTTTGGCTAACTCCATTTGGTTTGCCATTGACGTTAGA
+ACCGGGTCTTGTTTACCCAGAACGGTTGCCGCGACGGTAAGAAGATCGCGCTGTAAGTTA
+TAGAGGTTATGCAGCGAGTGGTTAGACGTCTTCTGATGCTGTAGATAATTCCCCCATGTC
+GCGCCAGGTTCTCGCAGGACAATAATTTCCGGGCGAGCGTCGGGCGCTTTAGCCGGCGCT
+TTGCCCTGGCCTGAGAGAATCTGCATTCCGTTGTATAAGGTTTTTTGTAGGCTTTTAAAA
+GCCTCCTGGGTTTTTAGTGAAGCTGAGTGATAGAAGCTCTGTATTTGCATAGCGTTTTTA
+ATATTCCTGAATAGGGGAGTGGGAACATTCAACAGGGTTAACAATCTTTTAAAAGGATGT
+GACTTTTATGCACCAGGAACTTTAAAAAAATGTCCTTTTTAATGAGGAAACGCTTCTGAT
+CAGGCGGGGAGGCATCCTGACGTCCATACGTAGTGGCGATCATGGGGGAGATCGGTACAT
+CAAATGTTCATAAAATCTACAAACTTCACAATTTAGGGCACAACTTTTATTGAAAACCCA
+CCTTCTTGATTCAGATCAAATTCACCGATTTACTCCTGCGTAAAGTAACGGCGTTACATC
+AAATGTTATACAGGTGTGTGTATGCCAGCAAAGCCCCGGACGAGTAAGACCGTGACGAAG
+AATATTCGTTTTTCCTATTCCATGCTTGAACAGATAGAATTCGCGTTGAAATCTGAAAAG
+ACGCGGAATTTTTCAGCATGGGTAAAAGAGGCCTGTCGGGAAAAGTTATGTAACACGGGA
+CATAAGCTGTAGTTATCGTCTTATGTAAGAGGGGGCGGCCATTTTGAAAAGAACAACGTG
+CTTATATACCTCCTGGGTCTTTGCCGCTTTTGTCTCTCTGCTGATATTTGTCTGGAGTGT
+CATAAACTATCCTCTCTATGAATCCATAATAATTATTGTCTTTTATATCTGGCTAATTCT
+GGTACCGCTTTATCTTATTGTGTATGAGTGGCTAATAGATTGTCATTAAATTTATGGCTG
+CGTACTTGAAAAGTGATATTTCATATCTGTGCGGTAAGTCATTGTCGTAATAATATTATT
+GGTCAGGCGACGGGCGAGCGTCTGCGCATTTTGCATCGTTTTATCTTCAAAATTTTGCAG
+TAAGCGTTGTGCTTCTTTCGGATGCGACGCATATAATCTCAGATAGCTCTGCTCCATCTT
+ATACTGTTGCTTAGCTGTTTGCTGTTCAAATGTTTTCCAGGCATGTTGCACATCTGGCGC
+AAACGTATTGTAGTCTTGCATAACCAGTGTTTGCAGCGTGCGGAATGTCCAGTAGGTAGA
+GTCGTTGCTCGCCCGATCGGTTCCTTTATCATCTCCGGGTTGATAATGACGCATCCCCTG
+GTAATAGGGGAGATAGACGCTAAGAGATGGCATTCCATAGGCGATGTATTCTACGTTGCC
+GATAGCCTGCGGTAATTTCGGTCTGACCTGTAAAATATGTGACTCCTGGGTACGAAAAAC
+GGATATAGGTCGCCATGGTTCTTGTGGATTATGACTGGCATAAGGGTCGTGCGACGTTCC
+CTGATAGTGATTGCGTAACGCGTTTTTTACTGCCGCCACGCTGATCTTCGTTATTGGCGT
+TAAAAAAACAGAAAATGTTTCCCCTTCGCTAACGACCGTATCCAGATGCGGATTAAACTG
+GTGTTGTAGCGTCCAGACGCGCGGATAATTATAGGTGGTATCGTTTTTGTTATCCTGCGA
+ATAGGCTTGATGAAAGTCGAATTCGCCGCGGGCCGGATCATATAATCCCTGCTTTTTCGC
+AAAGCTTACTAACGTTGGTGACGCCATATAATTCGCGTTATCATTCGGATCGTAATGGCG
+TAAACGTCCCTGATTGGCGGAAACGAAATAGCTATCTGCCGGAAGTCGTACTGCCAGCCA
+TTGATGTCCGCTTCCCGTCTCCAGATACCATATCTCTTTGCTATCAATAAACGCGACGCC
+GAAACCTTCGCCCGCGCCTTTTTGTTCAATAATATCTCCCAGTAATTTGGCGCCCTGACG
+CGCCGATTGCGCCACTGGCAGGATCACGGACTCAATGGCGTCTTCCGTGATTCCCGTTTT
+TGTCACGTAAGGATCGGCAGCCAGCGCCGCTCTGCCGTTGTAAATGGTTTCCGTTGCGCT
+CATTCCGACGCCCGCCGAATTGAAACCGGCTTCACCCATGGCGTTATCGTTAGTATCAAA
+GTCATGAATCGCCGTATAGCGCATCGCTGTCTCCGGAAGCGGCCAGCTAAAATTGTTGCG
+ATGTGCTTTATACTCGCCTTGTTGATGAAACGCGACGGGATGAATAACCTTATGCTTGGC
+GTTATTTGCCGAGCCATCCTCGTTGCGCGCGATAATAAAGGAGCCGTCAGCCGAAGCCTG
+ATTGCCTACCAAAAGGGTAGTACAGGCGATGACTTTACCCATACCCAGCAGCGTAACGGC
+GAAAGCAAGATACTTTTTCATAAAGGTTCCCACTGAATAACGCGTTATGGGATGAATTGA
+CCCTGGATTGGAAACCGAGAAAGTGATCGAGCCAGCAATATTCTTTACCGGCATCCTTTA
+TTTTCTTTTTATTGAGGTTGTATTGATAACCACAGCCCTGTGGCAGGGAAGGGGAACAGA
+ACCTGTACTGACCTTAGCTATCACCGCTATCAGGCAGACGAACCGAAAAGATATTATGTT
+CATCGGCATAGCGGTAAGATGCCGAGCCACCGTGCAATAGGGCAATCGCGTTAACTAACG
+ATAACCCCAGGCCGAAACCGGCAGTGTAGCGGGCATTATCTCCTCGCCAAAAACGCCGGA
+AAAGCTTATCCGCATCGGCGGTGGGGCTGCCCGGATTAGCGACCCGAATTTCTGCAACGT
+TATCATCATAAGCGCTTTCAATACGTATCACGGCGTTTTCATCAGAATAACGGATGGCAT
+TCGTCAGCAGGTTTGAGAGCACTCTTTGTAATAATATTTCGTCAGCCCATACCGTTCCCT
+GACATTGATTTATAAAACAGATGTGCTTCTCTTCGGCAAGGGGGCTAAGATAATCCAGCA
+TATTTTCGACCAGCGCATTGAGCGAAACAGGCTGTTTTTTTACCGCTATATTCTGGTGCT
+CCGCGCGTGCCAGAAAGAGAATATTTTCTGTCAGTCGCGACAGTCCCTCCAGCTCTTCAA
+TATTATCGACAAGGGCTTGTTGATACTCTTCGGCGCTGCGTTCCTGACTCAGCATAACCT
+GATTCTTCCCCAGTAAAATATTAACCGGCGTGCGCAGCTCATGCGCCAGATCGTCGGCAA
+ATTGGTTCAGGCGTTCAAAATCGTCGGAAAGCTTCTGGCGCATGGTATTTAGCGCTTGCC
+CAAGCGGCCTGAGCTCGACGGGTAACGCCTGTTCCGCCAGCGGCTGGCGAAGTGTGCCGC
+TATCTGTCGCCGCGGTGAGTCGGCTGAGCGACGTAATGGCCCGCAGCCCGTTTCTGATGA
+CTAATGGACTGAGCGCCGAACAGACGAGGATCGCGATAAGGCTAATCAGCAAACTGTTGC
+GGCGATATTGCGCCAGCATTTGCCGCCTTTCCGTCGCCAGCCTGGCAATAGTAAGGGTCA
+GCGGGTTATCGCCGCTTCTGGCGTTTACTCGTACCGCGGTCAGCTCCGTGCCTTGTACCG
+CCTGGCGAAATAAGGTTTCGCGGGTGATGTTTTTAGCCAGCGGAATCTCGTTAAAGCGTT
+GGTCGGGGATGCCGCTATGATTAATCGCAACATTATGGCCTGTTGCTGAGTGGATCAATA
+AGATATCCTGCTTCGTATCCACCATCCGATTGAAATAGAGCGGCAGATTTTCCGGCCTGG
+CGCCATCCAGTAACAGTTGCTGCATTTGCGCCGCCCGATTTATTAGCGTCATATCATCCC
+GATACGTTAATTCTTTGCTCAGCGCGTTATAGAGCGTCCAGCTAATGCCGGTACAGGCGA
+GGATAAGTATGGCGATAAAAGAAATTGTCAGGCGCAGCGTCATTGATAACTTAACCATTC
+TGCGACGTTTCCGCCTGTAATCGATAACCCATCCCCTGGACGGTCATAATGAGCTTCTTT
+TCAAATGGATCGTCTACTTTGGCGCGCAGCCGACGAATCGCGACATCAACGGTGTTGGTT
+TCACTATCAAAGTTAATTCCCCAAACTTCGCTGGCGATCGCGGTTCGGGGCACGATTTCC
+CCTGCCCGGGACGCCAGTAACCAGAGGAGCAGGAATTCTTTGCGGGTCAGGGAAATCGGT
+TTGCCATTTCGTAACACCGATTGCTTTGTGGCATCCATGTCCAGACCATTGATCGTCAGT
+CGGGTAAAGACCGGGACATGCTGTCTGAGTTGAGCTCTCACCCGGGCCAGCAGTTCGGCG
+AAGGAAAAAGGCTTAACAAGGTAATCATTAGCGCCCGCCTCAAGACCTTTGACGCGATCC
+TCAACCGAGTCGCGCGCCGTCAGGCAAATAACAGGGGGCTGATATGCAGTGCGCAACGCG
+CGTAAAACCTGCCATCCATCAAGCCCCGGCAGCATAATATCAAGAATAATCAATGAATAA
+TGTTCCTGAAGGGCTAGGTGTAATCCGTCTCGTCCATCACAGGCATAATCAACCACATAG
+CCTGCCTCCGTGAGTCCCTGACGTACCCACTCAATGGTTTTCTGGTTATCTTCAATCAAT
+AAAATCTTCATCAACGCAGTATGCCATAGGCTTGTTAGCGAATCCGTAAATCTCCAACAA
+GATGACATAATTGTCATGTCCGTGTAAGGTTAATCCTGGACGCGCCAGATATATTTTCCT
+GCATCAATACCGTAAAGGAGTGAAGCATGAAACGATATATACTGGCTACCGCGATAGCGT
+CTCTTGTTGCAGCCCCGGCAATGGCGCTGGCCGCTGGCAGCAATATTCTCAGCGTACATA
+TTCTCGATCAGCAAACAGGCAAACCAGCGCCCGGCGTGGAGGTGGTACTGGAGCAGAAAA
+AGGATAACGGATGGACGCAATTAAACACCGGGCATACCGACCAGGATGGACGAATTAAAG
+CACTGTGGCCCGAAAAAGCTGCCGCGCCGGGGGATTATCGCGTTATTTTTAAAACCGGCC
+AGTATTTTGAAAGTAAAAAACTGGACACGTTTTTCCCGGAGATTCCCGTCGAGTTTCATA
+TCAGCAAAACGAATGAGCACTATCATGTGCCGCTGTTATTAAGTCAGTATGGTTATTCAA
+CCTATCGCGGGAGCTAATTTAGAGCCTATCCTATTAGGGCTATTTTACTTGCCATTTTGG
+TCCTGGGCAGTGCTCGCCAAAACGCGTTAGCGTTTTGAACGCCGCTTGCGGCGGCCCGAA
+GGGCGAGCGTAGCGAGTCAAACCTCACGTACAACGTGTACGCTCCGGTTTTTGCGCGCTG
+TCCGTGTCCAAACAGGCTGCGCCAATAACGCCTGGTGGGACAGGCTCTTAGATTTTATTA
+ATCGCCGGGATTTATGGCGAGCAAACATCGCGGCGGGAATAAAAATCTTCAGCGTATCGA
+CTCTCCTCCCACAAGCGGTGGTTATCCCGCTTGTGGGTATGAGTGACGGTTAAACAGGCG
+CTTCCATCTCAAGTCTGACCGGATGAAAACGGCGTTTGAAATAAATCAGGCCATGCCCCT
+CCTGGCTAAGAATAATATTTTTGATCGCCACCAGATACACCAGATGCGTGCCAATGGTTT
+GTACCTCGCTGATCTCGCCTTCAAGACTGGCCAGCGCGCCGTTAAGTACCGGCTGGCCCA
+GCGGCCCGTTTTGCCAACATGGCTGGTGAAAACGCTCCTCCATCGCCATCCCCGTCATAC
+CGGCAAAGTGGCGCGCCATCAGCTCCTGCTCATGGTTAAGTACATTAATGCACAGCCTGC
+CGTTGCCCTGAAAAACGGGGTTCATGGCGCTATTGGCATTAATACATACCATCACGGAGG
+GCGGCGTATCAGTGACTGAGCAAACCGCTGTTGCGGTGATACCGCAGCGTCCGGCGTGAC
+CCGCCGTGGTTACGATGTTGACCGCTGCCGCCAGACTTGCCATCGCATCGCGAAAACGCA
+GACGTTGTTCATCTACTTGCATGAGAACCTCCTGCCGCGTTATTTCAGCAGCTTATCCAG
+TTGATTGATGTCGTCGTTATTGTGCAAATGCGAAACCGTCCAGCCATTCTGATCGTATTC
+GGAGAGGCAGCGATCGACCATTGCCATCATCTTATCCATATTGCCGGAGCTCTGGGCCTG
+ACGCAGACACTGCAGACGAATTTCATCCTGGCTGCCCGAGTAGTTAATCTCGTACAGCTC
+ATGGCGACCGCCAAACTCGCTGCCGATGGCATCCCACATCAATTTAAGAATTTTGATACG
+TTCAACATGGTCCATTCCGTTAGAGCCGCGTACGTATTTCGCCAGGTACTGGTCGATTTG
+CGGATTATTCAGATCGCGGGCGCTGGAAGGCAGGTAAATCAGGCCGCTGGTAACGTTACG
+TTCAATAATATTTTTAATTTTCGCGTAGGCCATTGGGGCCATCACACGATAGGTTTGCAG
+CGCGGCGTGGTCCGGTAGCCAGGCGCCGTTTACCCACGGGGTTGCTTCAGAACACATAGA
+ATCGCTCAATGCCCAGAACATATTGCGCCAGGCCACGACTTCGCCGAGATCGGCCTGCAC
+GCCCCGGAACTCTACGGTACCCGTACATTCGAGCGATTTTTTCAGCAGCGCGGTAATGAA
+ATCAAGTTTTACCGCCAGACGAACACAGGCTTGCAGTGGATACATACGGGCAAAGCCGCC
+TTCCATCGTCCAGCGACGACAACGATCGAAATCACGGTAAATTAATACGTTTTCCCACGG
+GATCAGCACCTTGTCCATCACCAGAATGGCATCGTTTTCATCAAAACGGCTGGAGAGGGG
+ATAATCAAACGGCGAGCCCGTCGCGCCCGCGACCATTTCATACGAGGCGCGCGAAATAAG
+TTTTACGCCTTCGGCATCCATTGGCGCGACAAACATCAGAGCAAAATCCGGGTTTTCGCC
+CATCACCTGGGCTGAGCCGAAACCAATCATGTTGTAGTGAGTCAGGGCGGAGTTAGTGGC
+GACAACTTTCGCCCCGCTGACAATAATCCCGGCGTCCGTCTCTTTCTCCAGCTTGATATA
+GACGTCTTTCACTTCGTCGGCAGGTTTGTGGCGGTCAATGGGCGGGTTGACGATTGCATG
+GTTAAAGTACAGGCCGGTCTCCTGAATACGGGTGTACCAGTTACGGGCGTTCTGCTCAAA
+CTGGCCGTAGAAGGCTGGGTTAGCGCCCAGAGCGCAGCCAAAGGCGGCTTTGTAATCCGG
+TGTGCGTCCCATCCAGCCGTAACTCAGGCGTGACCACTCGGCGATAGCATCACGCTGTTG
+GCGCAGATCGTCTGCGCTTTTCGCCACGCGGAAAAATTTATGCGTATAACCGCCGCTGCC
+GGTATCGGTATTCCAGCACAGGGTGTAAGCGGGAGGGGATTCCCGTGTCGGCGGCGTGGG
+AAGGTAAGAATACTATGCTTCCGCTTCGCTATCAGGATGCTGGCGCCCCAGAGCAATAAG
+ATCGTCCAGCAGCAGCATCAATTGCTGTGTTTTTTCGGGCGTGAAATCGGCCTCAATTTT
+TCGATAAGCCTCTTCTACCTCGCTCCGGGCACGGGCGTACAACGTTTGTCCCTGCTCCGT
+CAACATGACATATAACTTACGCTGATCGTTAACCGGCTTGAGTCGCAACACCAGTCCGTC
+TCGCTCCATGCGCGTCAATATTCCGGTCAGACTTGGACGCAAAATACAGGTACGAAAGGC
+CAGCTCGTGAAAATCCATAGAGGGGCTATCGGCCAGGATTCGCACAATGCGCCATTGCTG
+GTCGGTCAGATTGTGGCTTTTAACGATGGGGCGGAAATAGGTCATTGCCGCTTCGCGCGC
+CTGAAGCAAGGCGATGGTTAATGAATCATGCATAAGCGTTTCTCTTTTGCAGAATTATTA
+ATACCTGAATAATCGTGTTTACCGATGTGAGCTATGACATCTGTTTTATGTCCAAAGTTT
+AATAGAAACAAGGGGTTTTATTTAACTATTTGATATATATGTATTTAATAATAAATTTGT
+GAAAATATTGTTAATCACATCATAAATACTTTACTTAAGCTTGCTAAATGTACAGCGAAA
+GCATAAATCTAATCATTAATATGTTAATGAAATCACAGCCCGTTAAATCGGCCTGAGGAG
+TTTATGTATGAAGGGTACTGTTTTCGCCGTTGCGTTAAACCATCGCAGCCAGCTTGATGC
+CTGGCAAGAGGCTTTCTCTCAGCCTCCCTATAATGCGCCGCCTAAAACCGCAGTGTGGTT
+CATCAAGCCGCGTAATACGGTGATTCGTCACGGCGAACCCATTCCTTATCCGCAGGGAGA
+AAAGGTACTGAGCGGCGCGACAGTGGCGCTCATTGTGGGGAAAACCGCCAGCCGGATACG
+CCCTGAAGCGGCGGCGGACTATATCGCCGGGTATGCGCTGGCTAACGAGGTCAGCCTGCC
+GGAAGAGAGCTTTTATCGCCCGGCGATTAAAGCGAAATGTCGCGATGGCTTTTGCCCGCT
+GGGTGAAATGGCGCCGCTGAGTGATGTGGATAATCTCACCATTATCACTGAAATCAACGG
+ACGAGAAGCGGACCACTGGAATACTGCCGATTTACAGCGTAGCGCCGCACAACTGCTTAG
+CGCGTTAAGTGAGTTCGCTACACTTAACCCTGGCGATGCGATCTTACTTGGTACGCCGCA
+GAATCGCGTTGCGCTGCGTCCCGGCGATCGGGTGCGTATTCTGGCGAAAGGTTTACCCGC
+GCTGGAAAATCCGGTTGTCGCAGAAGATGAATTCGCCCGCCACCAGACGTTTACGTGGCC
+GCTGTCAGCGACGGGAACGTTATTTGCGCTGGGGTTGAACTACGCCGATCACGCCAGCGA
+GCTGGCATTTACGCCGCCGAAAGAGCCGCTGGTATTTATCAAAGCGCCAAACACCTTTAC
+CGAACATCACCAAACGTCGGTGCGCCCGAACAACGTCGAATATATGCACTACGAAGCCGA
+GCTGGTCGTGGTGATTGGCAAAACGGCGCGTAAGGTGAGCGAAGCCGAAGCCATGGAGTA
+TGTGGCCGGTTACACCGTCTGTAACGACTACGCGATCCGCGACTATCTGGAAAACTACTA
+CCGTCCGAATCTGCGGGTAAAAAGCCGCGACGGCCTGACGCCGATAGGCCCGTGGATTGT
+GGATAAAGAGGCGGTTTCTGATCCGCACAACCTGACGTTACGCACCTTTGTCAACGGTGA
+GCTGCGGCAGGAAGGGACGACCGCCGATCTGATCTTCAGCATCCCGTTCCTGATTTCTTA
+TCTGAGCGAATTTATGACGTTGCAACCGGGCGACATGATTGCCACCGGTACGCCGAAAGG
+GCTGTCCGATGTGGTGCCGGGGGATGAAGTTGTCGTTGAAGTAGAAGGCGTGGGTCGCCT
+GGTTAACCGAATCGTCAGTGAGGAGAGCGCAAAATGAAGAAAATAAATCATTGGATTAAC
+GGCAAAAACGTTGCAGGTAACGACTACTTCCAGACCACTAACCCGGCGACCGGTGATGTG
+CTGGCGGAAGTAGCCTCCGGCGGTGAAGCAGAAGTGAACCAGGCTGTCGCGGCGGCAAAA
+GAGGCGTTCCCGAAATGGGCCAACCTGCCGATGAAAGAGCGCGCGCGCCTGATGCGCCGC
+CTTGGCGACCTGATTGACCAGCATGTGCCGGAAATCGCGGCGATGGAAACCGCCGACACC
+GGCCTGCCTATTCACCAGACTAAAACGTGCTGATCCCGCGCGCCTCGCATAACTTCGAAT
+TCTTCGCCGAAGTGTGCCAGCAGATGAACGGCAAGACCTATCCGGTTGACGATAAAATGC
+TCAATTATACGCTGGTGCAGCCCGTCGGCGTCTGCGCGCTGGTGTCGCCGTGGAACGTGC
+CGTTTATGACCGCGACTTGGAAAGTTGCGCCGTGCCTGGCGCTGGGTAACACCGCGGTGC
+TCAAAATGTCCGAGCTGTCGCCGCTGACTGCCGACAGGCTGGGCGAGCTGGCACTGGAGG
+CAGGAATTCCGGCAGGCGTGCTGAACGTGGTGCAGGGCTACGGCGCGACGGCGGGCGATG
+CGCTGGTACGCCACCATGACGTGCGTGCGGTGTCGTTTACCGGCGGTACCGCCACCGGTC
+GCAATATCATGAAAAATGCCGGGCTGAAAAAATACTCGATGGAGCTGGGCGGCAAATCGC
+CGGTGCTGATTTTTGAAGACGCCGACATTGAGCGCGCGCTGGACGCCGCGCTGTTCACCA
+TCTTCTCGATCAACGGCGAACGCTGCACCGCTGGGTCGCGCATCTTTATCCAGCAGAGCA
+TTTACCCTGAGTTCGTGAAGCGCTTTGCCGAACGCGCGAATCGCCTGCGTGTCGGCGATC
+CGACCGACCCGAACACCCAGGTCGGCGCGCTGATTAGCCAACAGCACTGGGAGAAAGTCT
+CCGGTTATATCCGCCTCGGCATTGAAGAGGGGGCAACGCTGCTGGCGGGCGGTGCGGAAA
+AACCCACTGACCTGCCTGCGCATCTGAAAGGCGGTAACTTCCTGCGCCCAACCGTGCTGG
+CCGATGTCGACAACCGTATGCGCGTTGCGCAGGAAGAGATCTTTGGGCCGGTCGCCTGCC
+TGCTGCCATTCAAAGACGAAGCGGAAGGGTTACGTTTGGCGAACGATGTGGAATACGGTC
+TGGCCTCTTATATCTGGACCCAGGACGTGAGCAAAGTGTTGCGCCTGGCGCGTGGGATTG
+AAGCCGGCATGGTCTTCGTCAACACCCAGAACGTCCGCGACCTGCGCCAGCCGTTCGGCG
+GCGTGAAAGCCTCCGGTACCGGGCGCGAAGGCGGCGAATATAGCTTCGAAGTGTTTGCGG
+AAATGAAAAACGTCTGCATCTCAATGGGCGACCATCCTATCCCAAAATGGGGAGTTTGAT
+ATGGGCAAGTTAGCGTTAGCAGCAAAAATTACCCACGTGCCGTCGATGTATCTTTCTGAA
+CTGCCAGGAAAAAATCACGGTTGTCGTCAGGCAGCCATTGATGGGCATATTGAAATTGGC
+AAGCGTTGCCGCGAAATGGGCGTTGACACCATTATCGTATTCGACACCCACTGGCTGGTG
+AATAGCGCTTACCACATTAATTGTGCCGACCATTTCCAGGGCGTCTATACCAGCAACGAA
+TTGCCGCACTTTATTCGCGACATGACCTATGACTATGACGGTAATCCGGCGCTCGGCCAT
+CTGATCGCCGACGAGGCGGTCAAACTGGGCGTGCGCGCCAAAGCGCACAACATCCCGAGC
+CTGAAGCTGGAGTATGGCACGCTGGTGCCGATGCGCTACATGAACAGCGACAAGCACTTC
+AAAGTGGTCTCCATCTCGGCGTTCTGCACTGTGCATGATTTTGCCGACAGCCGCAAACTG
+GGCGAAGCCATTCTCAAGGCGATTGAGAAATATGACGGTACCGTAGCGGTATTCGCCAGT
+GGTTCTCTGTCGCACCGTTTTATTGACGACCAACGGGCGGAAGAGGGGATGAACAGCTAC
+ACCCGCGAGTTCGATCATCAAATGGACGAGCGCGTGGTCAAGCTGTGGCGCGAAGGCAAA
+TTCAAGGAGTTTTGCACCATGTTGCCGGAGTACGCCGACTACTGCTACGGCGAAGGCAAC
+ATGCACGACACGGTCATGCTACTGGGAATGCTGGGGTGGGACAAATACGACGGCAAGGTG
+GAGTTCATCACCGACCTGTTCGCCAGCTCCGGTACCGGCCAGGTAAACGCTGTTTTCCCG
+CTGCCTGCGTAAGGGGGGTTTATGCCGCACTTTATTGCTGAATGTACTGAAAATATTCGC
+GAGCAGGCTGATTTACCAAGCCTGTTCAGCAAGGTAAACGAGGCGCTGGCCGCCACCGGG
+ATTTTCCCCATCGGCGGTATCCGCAGTCGCGCCCACTGGCTGGATACCTGGCAGATGGCT
+GACGGTAAGCATGATTACGCGTTTGTGCATATGACGCTGAAAATCGGCGCCGGGCGCAGC
+CTGGAGAGCCGTCAGGAAGTCGGCGAAATGCTGTTTGGGCTGATTAAAGCCCACTTCGCC
+GACCTGATGGAGAACCGCTATCTGGCGCTGTCGTTTGAGATTGCCGAGTTACATCCAACG
+CTCAATTACAAACAAAACAACGTACACGCGTTATTTAAATAGCACACTCTTTCGCCCGGT
+GGCGCTGCGCTGACCGGGCCTACAAAAAAACGATGCACGAAGCAGTACCGAACCGTAGGC
+CGGGTAAGACGCACCCGCGTCGCCACCCGGCGCAGCAGCACCGAATGAGGTAACAGGAAG
+CAACTATGCTCGATAAACAGACCCATACCCTGATCGCTCAGCGACTTAATCAGGCTGAAA
+AACAGCGTGAACAGATTCGCGCAGTGTCGCTGGATTATCCCAACATCACTATTGAAGATG
+CCTATGCCGTACAGCGTGAATGGGTCAATATCAAGATTGCCGAAGGGCGCACGCTCAAAG
+GCCACAAAATCGGCCTGACCTCAAAAGCGATGCAGGCCAGCTCGCAAATCAGCGAACCGG
+ATTACGGCGCGCTGCTTGACGATATGTTCTTCCATGACGGCGGAGATATCCCCACCGACC
+GTTTTATCGTCCCGCGTATTGAAGTGGAGCTGGCGTTCGTGCTGGCGAAACCGCTGCGCG
+GCCCTCACTGCACGCTGTTCGACGTCTACAACGCCACGGATTATGTGATTCCGGCGCTGG
+AACTGATTGACGCCCGCAGCCACAACATCGACCCGGAAACCCAGCGCCCGCGCAAAGTGT
+TCGACACCATTTCCGACAACGCCGCCAACGCCGGGGTGATCCTCGGTGGTCGCCCCATCA
+AACCAGACGAGCTGGATCTGCGCTGGATCTCCGCGCTGCTCTATCGCAACGGCGTGATCG
+AAGAAACCGGCGTCGCCGCAGGCGTGCTGAATCATCCGGCCAACGGCGTGGCGTGGCTGG
+CGAACAAGCTTGCCCCCTACGATGTCCAGCTTGAAGCCGGGCAGATCATCCTCGGCGGCT
+CGTTCACCCGCCCGGTGCCGGCGCGCAAGGGCGACACCTTCCATGTCGATTACGGCAACA
+TGGGCGCGATCAGTTGCCGGTTTGTGTAAGGAAAAAACGATGAAAAATGCTTTCAAAGAC
+GCGTTAAAAGCGGGGCGCCCGCAAATCGGTTTGTGGCTGGGGCTTGCCAACAGTTACAGC
+GCTGAACTGTTAGCGGGCGCCGGCTTCGACTGGCTACTGATTGACGGTGAACACGCGCCA
+AACAACGTGCAGACGGTGTTGACCCAGTTGCAGGCGATTGCGCCTTATCCCAGCCAGCCG
+GTGGTGCGTCCGTCATGGAACGATCCGGTACAGATTAAGCAACTGCTCGACGTCGGCGCG
+CAAACGCTGCTGATACCGATGGTGCAGAATGCCGATGAAGCGCGAAACGCCGTGGCGGCT
+ACGCGTTATCCGCCTGCCGGTATTCGCGGCGTGGGCAGCGCGCTGGCGCGGGCATCGCGC
+TGGAATCGCATTCCGGACTATCTCCACCAGGCCAACGACGCCATGTGCGTACTGGTGCAG
+ATTGAAACGCGTGAGGCGATGAGCAATCTGGCGTCAATTCTCGACGTGGATGGCATTGAC
+GGCGTGTTTATTGGCCCGGCGGATCTCAGCGCCGATATGGGCTTTGCCGGCAATCCGCAG
+CACCCGGAAGTGCAGGCGGCGATTGAGAACGCCATCGTGCAGATACGCGCGGCGGGGAAA
+GCGCCGGGGATTCTGATGGCCAATGAAGCACTGGCGAAACGTTATCTGGAACTGGGGGCG
+CTATTTGTCGCCGTCGGCGTTGACACCACGCTGCTGGCGCGCGGAGCGGAGGCGCTGGCG
+GCGCGCTTTGGCGCAGAAAAAAAACTGTCCGGTGCGTCCGGCGTCTATTAAGCCTGGGCC
+GGTAAGCGCAGCGCTACCGGGCAACCGTAGTACCCTACAAAATTCCCATCAGAGGAAAAA
+AAATGAGCGACACATCATCTGCACTTCCGGAAAGCCCCGAGTCTGTCGGTTCGCACAACG
+CGCTCAGCACGGGTCAACAAACCGTCATAAATAAACTGTTCCGCCGACTGATCGTATTTT
+TATTCGTGTTGTTTATCTTCTCGTTTTTAGACCGTATCAACATCGGTTTTGCCGGGTTGA
+CGATGGGGCAGGATCTGGGGTTAAGCGCCACCATGTTTGGTCTTGCCACGACGCTGTTTT
+ACGCCACCTACGTCATTTTCGGCATTCCCAGCAACGTGATGTTGAGCATCGTCGGCGCCC
+GCCGCTGGATTGCGACCATTATGGTGCTATGGGGCATTGCATCTACCGCCACGATGTTCG
+CGGTGGGACCGAAAAGCCTGTATGTGCTGCGAATGCTGGTGGGCATTACCGAAGCGGGCT
+TTTTGCCAGGAATATTGCTCTATTTAACCTACTGGTTCCCGGCATTTTTCCGCGCCCGCG
+CCAACGCATTATTTATGATTGCCATGCCGGCCACTACCGCGTTGGGGTCAATTGTCTCCG
+GCTATATTTTATCGCTGGACGGCATATTCAATCTGCATGGATGGCAGTGGTTATTCCTGT
+TGGAAGGATTTCCGTCAGTTTTGTTAGGCATTATGGTCTGGTTTTACCTGGATGATACCC
+CGGCAAAAGCCAAATGGCTGACGGCAGAGGATAAAAAATGTTTGCAGGAGATGATGGATA
+ATGATCGCCTGACGCTGGTTCAGCCTGAGGGGGCCATCAGCCATAACGCCATGCAGCAGC
+GTAGCCTGTGGCGCGAAGTATTCACGCCAATTGTACTGATGTATACGCTGGCCTATTTTT
+GCCTTACCAATACGCTTAGCGCCATTAGTATCTGGACGCCGCAAATCCTGAAAAGTTTTA
+ATGAAGGCAGCAGCAATATCACCATCGGCCTGCTGGCGGCGATCCCGCAGATTTGTACTG
+TTCTGGGCATGATTTACTGGAGCCGCCATTCGGACAAACATCAGGAGCGTAAACACCACA
+CTGCGTTACCGTTCCTGTTTGCCGCCGCGGGCTGGCTGCTGGCGTCGGCGACCGACCGTA
+ACCTGATCCAGCTCCTGGGGATCGTGATGGCATCCACGGGTTCCTTTAGCGCGATGGCGA
+TCTTCTGGACCACGCCGGATCAGTCGATCAGTTTACGCGCCAGGGCGATAGGCATTGCGG
+TCATCAATGCCACCGGCAATATTGGCTCCGCGCTCAGCCCGGTTATGATTGGCTGGCTAA
+AAGATATCACTGGTAGCTTCAATAGCGGACTCTGGTTTGTCGCTTCTCTGTTAGTCGTCG
+GCGCCGCCATTATCTGGCTCATTCCCATGAAAGCATCGCGTCCGCGCGCCACCCCTTGAG
+GAGAAACTATGTGCCAACGTGCGATCGCCAATATTGATATCAGCAAAGAGTATGACGAAA
+GCATGGGCAGTAACGATGTGCATTATCAGTCGTTTGCTCGTATGGCGGATTTCTTTGGTC
+GTGATATGCAGGCGCATCGCCACGACCAGTTTTTTCAAATGCACTTTCTTGATACCGGGC
+AGATTGAGCTACAGCTCGACGATCATCGCTATTCGGTGCAGGCGCCGCTATTTGTGCTAA
+CGCCGCCCTCGGTGCCGCATGCTTTTATTACCGAATCGGATAGCGATGGTCATGTTCTGA
+CGGTACGCGAAGAGCTGGTTTGGCCGCTGCTGGAAGTGCTTTATCCCGGCACCAGAGAGG
+CCTTCGGCCTGCCGGGAATCTGCCTGTCGCTGGCGGATAAACTCAACGAGCTGGCGGCGC
+TCAAACATTACTGGCAGCTAATTGAGCGGGAGTCCACGGAACAACTGGCTGGCTGCGAAC
+ATACCTTGGTACTACTGGCGCAGGCGGTATTTACCTTGCTGTTGCGTAATGCGAAGCTGG
+ACGATCATGCCGCAACCGGGATGCGCGGTGAACTGAAACTTTTTCAGCGCTTTACCCTGT
+TAATTGACAACCACTTCCATCAGCACTGGACGGTGCCCGATTATGCCTGTGAGTTGCATA
+TTACCGAATCTCGTTTGACCGATATTTGCCGACGTTTTGCTAATCGCCCGCCTAAACGCC
+TGATTTTTGATCGGCAATTACGCGAGGCGAAACGACTGCTGCTTTTTTCCGACAATGCTG
+TCAACGAGATCGCCTGGCAATTAGGTTTTAAAGATCCGGCTTATTTCGCCCGTTTCTTTA
+ATCGCCTTGCTGGCTGTTCTCCTTCGCAGTTTCGCCAACGTGAAGTTCCTTCTTTTCTCA
+ACTAAGAAGAGTAAAAACATGATGAAAAAAAGCGTCGCTATGCTGGCGGTTTGTATGCTG
+GCGCAAAGCCACCTTGCCATTGCTGCCGGTGCTCCTGCGCCTCAAGAGATCAACATTGTT
+TTACTGGGCACCAAAGGCGGGCCTTCTTTGCTCAATACAGCCAGACTACCGCAAGCGACG
+GCGCTCACTATCGGCGATAAGATATGGCTGATAGATGCCGGCTACGGCGCCAGTCTGCAA
+CTGGTGAAAAATGGCATTCCACTGCGCAACATCAATACTATTTTGCTCACCCATCTGCAC
+AGCGACCACATACTGGATTATCCTTCCTTGCTGATGAATGCCTGGGCAAGTGGCCTGAAA
+GACCATACCATACAGGTTTATGGCCCGCCGGGAACCCAGGCGATGACGAAGGCTAGCTGG
+AAGGTCTTTGACAGGGATATCACGTTACGCATGGAAGAAGAGGGGAAACCCGATCCGCGC
+AACCTGGTTAAGGCGACCGATATCGGCCAGGGCGTCATCTATAAAGATGAACTGGTCACA
+ATAAGCGCGCTGAAAGTGCCTCATTCCCCTTTCCCGGACGGTGAAGCGTTTGCTTACCGT
+TTTGATACTCAGGGTAAGCGAATCGTCTTCTCTGGCGATACGTCCTGGTTTCCTCCGCTT
+GCAACGTTTGCCCAGGGGGCGGATATCCTGGTACATGAGGCGGTACATGTCCCTTCGGTA
+GCAAAACTGGCTAATAGTATTGGCAACGGAAAAACGCTGGCTGAAGCGATTGCGTCGCAT
+CACACCACGATTGAAGATGTCGGTAAGATTGCTCGCGAGGCCCACGTGAAAAAACTGGTG
+TTAAGTCATCTGGTGCCTGCGACGGTTGCGGATGACGTCTGGCAACAGGAAGCCATGAAA
+AATTACCCGGGCCCTGTCATTGTCGGTCATGACAATATGACGATAAGCGTACCGTAAGCA
+TCAGGGCAGGGGTAAACCAACGGGCTGACATCATGTCAGCCCGTTATGCTTTTGGCGATC
+AGCATGACGCGCAGAGCTTTTGTCTAAAACATTATTTTTTCTAAACACTACTTGCTGATT
+TTTATGCACAATAAAGGTAAGATGATTGCTCTGGTGAAATATCACTAAATAAGAATGTCA
+CGGATGGAATTTATACAGTGTTAAAAGCAATGCGTTTCTTTGTCTGCCGGCCATCAGTAA
+TATCCTCTGTACCGGCTCCTCGTTGCCAAAGTGAAGGTTAGATTAAACGAATCAAAAAAT
+ATCCGAACTGTACAATTTTTATATCAAACATATTTAACTGCAAAATACTGCAAACGTGCG
+CGAATACACTTAATCAGTAGTATGGCTAATGCATACTTTATTTCCTAAACTTTCTTATTA
+TCTATTTGAATATTTCTGGTTAAACCAAATGGACAAACGGATACCAGACACTCGAAAGGA
+TAACTGCAAGCTTCTGGTTTAGGATTGCAGTTACCAGGACAGTGGCTATTTTCTTTAAGC
+GATTTCCATAGAACAGGATTAAACCTGGTAACGTTGTAAACAGTAACGGGATAAAGTTTA
+TCGTTTATTAAGACCCCCTTATTAAAGGGGATGATAATGCTACCTGGAGGCATGTAAACA
+TCTGCTTGATACCATAAGGTCAATCTAAGATTTTTTAGGCTATGTATGCATGAGAACGAC
+ACTCCGGTAGAGGGACTTATAACTGTATCAACGACCTTCCATTCCATTACAGAAACCTTT
+TAAGTGAAATAGTCAATGGTGTAAATTACATTTTCCGCAAGCCTATTCAGGATAGATGAA
+AATCTGAGAAACATAACTCGTTGAAAACGATCGTTTTTTATTGACCACTCTATTTATATT
+GATTTTTTAATAAGTTATTTATTTTATGCTCTTATTTTGTTTACATTCTATTACATTTTT
+GTATTTTATACGTGGTGTAAATATTGGGCGGTAGTGGATGTTATAACGCTCAATTATTAA
+ACTGTAAGTGACTGTTGTATTTCTTATTTATAAATACCGCAACCTGTAAGCGCAGCGGTA
+CATTTTACCCGGCATTGACAGGGAGAAGATACGTATCAACCAGAGAGTACAAAACAGTGA
+AAGAATATATTCTTCAGGCAATAAATGATCGCTAACGTGTAAAAATAACCGACGAATCTA
+AAAAATGTGAGCGTGTGGCTGGTCTTTATTTAAACGATGATCTTCGCAATGGCGCATTAA
+TGGCTGACATTGGCGGTTCGTTGATCGGCTTGTGCGCGGTGAAAGGCTATATTTCTTCCG
+TTGCGGGAAGTATGTCAGAGGCATTCTGGTATTATACCGGGTGTATGTAAATCCGGGGTG
+GGCAGAAAGCCCACCCTCGGTTTATTGCCTTTATCGTGGATTAGGGATGCGAGATAAAGC
+GAGAAAGGCGTTGCAGCAGTAACCGGTTTTCTTCGCGCAGCCGTGAATTCTCTTCCAGCA
+GCGTTAACGCGACCGCGATCCCTGGCCAGTCGAGCGCCAGCTCCTCGCGTAAGCGTAGCG
+CGCGTTGTACCACGCTCGCTGCGCGATCGTCGAATTGCCAGTCGGCGTTATCGTCTTCGT
+AAGGCTCAATTACGCCAAGTCCGACGATTTCGTTTAGCTCCTCTTCCGTCACGCCGGTGT
+GCAAACAAAATTCGGTGATGGTAAAGGTGACAGTGATGTTAGCCATTATGCTTTCCCCCA
+TTGCTGGCGTGGGTCAAAGGACGACTGCGCGTCCGCCAGTTGTTGCCACAGGGCAGCTGT
+TTTCTCGTCAGGTTTCGGCGGCATAACGATTTTGATGATGGCATAGAGATCGCCAGTGTG
+CTTTTTACTGGCTAATCCTTTTCCTTTGATACGCAGCCGCTGACCTGCCTGGCTGCCGGG
+GGGAATGGTCAGCAAAATACGCTCTTTAAGCGTTGGCACAGACACCTTAGCGCCGAGCGC
+CGCCTCCCATGGGGCAAGCGGAAGGACGACTTCCAGATCCTGATTGACGATATCAAAGAG
+CGGATGCGGGGCAATATGGATAACGAGCCATAAATCGCCATTAGGTCCGCCGTTTTCCCC
+CGGCGTGCCCTGGCCTTTCAGTCTGATTCGTTGCCCGTTGCTGACGCCAGCCGGGATTTT
+CACATTCAATGTTTTGGGAATTTCCCGCTCCACCAGGCCGAACGCGTTATAAACGGGGAC
+GGAATAGCTAATCGTACGCTGGTGCTCTTCCAGCGTTTCTTCCAGGAATACCGCCACTTC
+AATTTCGATATCATGACCGCGTGCGGCGTGGCGGTGGTGCGAATGACGACCGTGCTGACC
+AAAAATAGACGAGAAAATATCATCAAAATCTTCGGCGTTATACGGCTGGCCTTCGTGTTG
+CTGGAACTGGCGATTAAATTGTGGATCGTTACGGTGTTGCCATAACTGGTCATACTCGGC
+GCGCCGTTGCTCATCACTCAGCACTTCCCATGCTTCAGCAACCTCTTTGAAACGGGCTTC
+GGCATCGGGTTCTTTGCTGACATCTGGATGGTACTTGCGGGCCAGTCGGCGATAGGCGGT
+CTTAATCGTCTTGAGATCGTCCGTCGGTTTCACGCCCATAATGGCGTAATAATCCTTAAG
+TTCCATAGCATCATCTCGCTAAATCAATACATACAGAAGGGACCCCAAAAAGGTTTCTCC
+ACTAAGTGTAGGGTAAACCTGAAAAGTGCGTATGAAAACACCAGTTATATCATTAGTAAG
+AATAAATTACGTTGTTCGACTATCAGAAGGTTGCGCAGCGCGCCGACATAACTTTACAGG
+GGAAAGGTTGCCAAAACCGCGCCAGTGGCTAAGATAACTCGCGTTAAACAGTGAGGGCGC
+AATGGCGAAACAACAACGGATGGGCTGGTGGTTTCTTTGCCTTGCATGTGTCGTGGTAAT
+GGTTTGTACCGCGCAACGCATGGCGGGCCTGCACGCCTTGCAGATGCAGGCGACGGCCTC
+TGCTGCGGTGGTCAGCGCTCCCTCCTCGACAGATGACGGCTCGCCGGTCACTCCCTGCGA
+ATTAAGCGCCAAGTCGCTGCTGGCGGCGCCTCCAGTACTCTTTGAAGGTGCTATCCTTGC
+GCTTTATCTACTGCTTTCCTTACTGGCGCCTGTCCGGGTCATGCGCCTGCCGTTTTCGCC
+TCCACGGGCTATTTCGCCGCCCACATTACGGGTACATCTACGATTTTGTGTCTTCCGTGA
+ATGACAGACCGGTTATTACTAACGGTTAATTACTCATTCACGGAGAAAAAATATGATGAT
+TTTATTCAGGCGGATACTGTTCTGCCTGTTATGGCTTTGGCTGCCCGTCTCCTGGGCGGC
+GGAAAGCGGCTGGCTGCGTTCGCCCGATAACGACCATGCCAGCATACGGCTACGTGCCGA
+TACGTCCGCTAACAGTGAGACCCGGCTGTTGCTGGATGTCAAACTGGAAAACGGCTGGAA
+AACCTACTGGCGCGCGCCGGGGGAAGGGGGCGTGGCACCCTCTATCGCCTGGAAAGGCGA
+CATGCCTGAGGTAAGCTGGTTCTGGCCAACCCCCTCGCGCTTTGATGTGGCGAATATCAC
+CACCCAGGGATATCACGACGAGGTGACCTTTCCGATGATCGTGCGCGGTACGCCGCCGGC
+GACCTTGCGCGGTGTGTTGACGTTATCAACCTGCAGCAATGTTTGTCTGTTGACCGATTA
+CCCCTTTTCCGTGACGCCCACTGTGCAGAATGCCGATTTTGCCCATGACTATGCGCGGGC
+GATGGGTAAAGTTCCGCTCCGCAGTGGGCTAACGGACTCGCTTGACGTTGGCTATCGCCC
+GGGAGAACTGGTGGTCACTGCTACGCGAGCGGCGGGCTGGTCATCGCCCGGGCTCTATCT
+TGACACCATAGATGACGTCGATTTTGCGAAGCCTCGCCTGCGCGTAGAGGGCGACAGGTT
+ACAGGCGACGGTGCCGGTGACGGACAGTTGGGGCGAAAAGGCGCCCGATTTGCGCGACAA
+ATCGCTGACCCTCGTGTTAGCCGATGGCGCTATCGCCCAGGAGAGCACGCAAACCATTGG
+CGCTGCGCCAGCGCAAACGCCGGACAATGCGGCGCTACCTTTCTGGCAAGTTGTAATGAT
+GGCGCTAATCGGCGGACTGATTCTTAATTTAATGCCCTGCGTACTGCCTGTTCTGGGCAT
+GAAACTTGGCTCTATTTTATTGGTAGAGGAAAAAAGCCGCTCTCACATCAGGCGACAATT
+TTTGGCTTCGGTCGCCGGTATCATTGCGTCATTTATGGCGCTGGCGGCGTTTATGACCCT
+CCTTCGCCTGTCAAACCATGCGCTGGCCTGGGGAGTCCAGTTCCAGAATGCATGGTTTAT
+TGGTTTTATGGCGCTGGTGATGTTGTTGTTTAGCGCCAGCCTGTTCGGGCTTTTTGAGTT
+CAGGCTTCCCTCATCTATGACCACGAAACTGGCCACTTACGGCGGTAACGGTATGTCGGG
+ACATTTCTGGCAGGGGGCGTTCGCCACGCTGCTGGCGACGCCTTGTAGCGCGCCGTTTCT
+GGGCACGGCGGTCGCGGTGGCGCTCACGGCGTCGCTGCCGACGCTGTGGGGGCTGTTCCT
+TGCGCTTGGCCTGGGAATGAGCGCGCCGTGGCTACTGGTCGCGATACGACCAGGGCTTGC
+GCTACGTTTACCGCGCCCCGGGCGTTGGATGAATGTCCTGCGCAGGATCCTCGGTCTGAT
+GATGCTGGGGTCGGCTATCTGGCTGGCGACGTTACTCCTGCCGCATTTCGGCTTCACTGC
+GTCAAAGAGCGCGCAAGACACGGTTCAGTGGCAACCGTTGAGTGAACAGGCAATCCAGTC
+GGCGCTGGCGCAGCATAAGCGGGTATTTGTCGATGTCACTGCGGACTGGTGTATTACCTG
+TAAAGTGAATAAATACAACGTCCTGCAAAAAGAGGATGTGCAGGCCGCCTTGCAACAGCC
+GGATGTTGTGGCGCTGCGGGGAGACTGGACGCTGCCGTCCGATGCCATTACAGATTTTCT
+GAAAACGCGCGGCCAGGTCGCCGTGCCGTTTAATCAGGTATATGGCCCCGGTTTGCCGGA
+AGGGGAGGCACTGCCCACTTTGCTGACCCGCGATGCGGTATTACAAACGTTGAAAAAAGC
+GAAAGGAATAACCCAATGAAATACATGATTGTTTTACTGCTGGCGCTGTTTTCGACGCTG
+AGCATCGCGCAAGAAACCGCTCCTTTTACGCCGGATCAGGAAAAGCAGATTAAAAATCTG
+ATCCATGCGGCGTTGTTTAACGATCCTGCCAGCCCGCGGATAGGCGCTAAACACCCTAAG
+CTGACGCTGGTGAACTTTACGGATTACAACTGCCCGTACTGCAAACAGCTCGATCCGATG
+CTGGAAAAGATTGTGCAGAAATATCCTGACGTTGCGGTCATTATTAAACCGCTGCCATTC
+AAAGGAGAGAGTTCCATACTGGCGGCGCGTATTGCGCTGACCACCTGGCGCGATCATCCG
+CAACAGTTCCTCGCGCTACATGAAAAACTTATGCAAAAGCGCGGTTACCATACGGATGAC
+AGTATTAAACAGGCCCAGCAGAAAGCAGGGGCGACGCCAGTGACGCTGGATGAAAAAAGC
+ATGGAAACGATACGCACTAATTTGCAGTTGGCAAGACTGGTCGACGTGCAAGGAACGCCA
+GCGACGATCATTGGCGACGAGCTGATTCCGGGCGCAGTGCCCTGGGATACGCTGGAAGCG
+GTGGTGAAAGAAAAACTGGCGGCTGCCAATGGCGGGTAAACTGCGGCGTTGGCTGCGTGA
+AGCCGCGGTTTTTCTGGCGCTCCTCATCGCGATAATGGTGGTCATGGACGTCTGGCGCGC
+GCCGCAGGCGCCTCCGGCGTTTGCCGCGACACCATTACATACGCTGACGGGAGAGTCGAC
+AACTCTGGCGACCTTGAGCGAGGAACGCCCCGTACTGCTCTATTTTTGGGCCAGCTGGTG
+CGGGGTATGCCGCTTTACCACGCCTGCGGTCGCTCACCTGGCGGCGGAAGGGGAAAACGT
+CATGACCGTTGCGCTCCGCTCCGGCGGTGATGCTGAGGTTGCCCGCTGGCTGGCGCGCAA
+GGGCGTTGACTTCCCGGTCGTCAATGATGCTAACGGCGCCTTATCCGCTGGCTGGGAAAT
+CAGCGTGACGCCAACGCTGGTGGTGGTTTCACAAGGTCGGGTTGTGTTCACCACCAGCGG
+CTGGACCAGCTATTGGGGCATGAAGCTTCGGCTGTGGTGGGCAAAAACGTTCTGAATATG
+CGCCGGGGTTTCCCGGCGCTAACGCGTTTACTGTAAGAAAAACCTCCGTTTTGCGAAATC
+GTTCCCGGAAAAATGATCCATTTCTGTCACACTCAGAACGATTTGATAACAACAAGAGGT
+CATAGGGATGAAAAAATCATTACTCGCTGTTGCTGTGGCAGGGGCTGTTTTGTTGTCATC
+CGCCGTACAGGCGCAGACAACGCCGGAAGGTTATCAATTACAACAGGTGCTGATGATGAG
+CCGCCATAATCTGCGGGCGCCGCTGGCGAATAATGGCAACGTACTGGCGCAGTCGACGCC
+GAACGCCTGGCCGGCGTGGGACGTTCCCGGCGGGCAACTGACGACGAAAGGCGGCGTGCT
+GGAAGTCTATATGGGACACTACACACGTGAATGGCTGGTCGCGCAGGGGCTGATACCGTC
+GGGAGAATGTCCGGCGCCCGACACGGTATATGCCTATGCGAATAGTTTGCAGCGCACCGT
+CGCCACCGCGCAATTTTTCATTACCAGCGCTTTCCCCGGCTGTGATATTCCTGTTCATCA
+TCAGGAAAAAATGGGCACTATGGACCCTACCTTCAATCCGGTGATTACCGATGATTCCGC
+CGCGTTCCGGCAACAGGCCGTACAGGCGATGGAAAAGGCGCGTAGTCAGCTACATCTTGA
+TGAGAGTTATAAACTGCTTGAGCAGATAACGCATTATCAGGACTCGCCGTCCTGCAAAGA
+GAAGCATCAGTGTTCGCTAATCGACGCGAAAGATACCTTCAGCGCGAACTATCAGCAAGA
+GCCTGGCGTGCAGGGGCCGCTGAAAGTAGGGAACTCGCTGGTGGATGCGTTTACCCTGCA
+ATATTACGAAGGCTTTCCGATGGATCAGGTCGCTTGGGGCGGGATCCACACCGATCGGCA
+GTGGAAGGTGCTGTCAAAACTGAAAAACGGCTACCAGGACAGCCTGTTTACCTCACCCAC
+GGTGGCGCGCAATGTCGCTGCGCCGCTGGTAAAATATATCGATAAGGTGCTGGTTGCCGA
+GCGCGTTAGCGCGCCGAAGGTTACCGTGCTGGTGGGGCATGATTCCAATATCGCGTCGCT
+GCTGACGGCGCTGGATTTTAAACCCTATCAGCTCCATGACCAGTATGAGAGAACGCCGAT
+TGGTGGTCAGCTTGTCTTCCAACGCTGGCATGACGGTAACGCTAACCGGGATTTGATGAA
+AATCGAGTATGTCTACCAGAGCGCCCGGCAGTTACGTAATGCGGAAGCGTTAACGCTCAA
+ATCGCCTGCGCAAAGGGTAACGCTGGAACTGAAAGGATGTCCGGTGGATGCGAACGGCTT
+CTGTCCGCTGGATAAGTTCGATAACGTCATGAACACTGCTGCAAAATAGCCGTATGCCCC
+CGCGCAGGCGGGGGCGTTTGTGTTATACGTTCTTACGTTCGATGACTTGTTCGCCCCAGA
+AGAGCGAGTCTTTGTCCGTTTTCTCAAAGGCTTTGATCAGCACCTCATCGCTACCTTCTT
+CCCATATTTTTTCTGCCAGTTTCTCGTCATAGTGAGCGACTTCAAAAATGGCTTCGGCAA
+TTTCCGGCGACGTATTACGCAGGCTTGCCCATTCGCCGACGCGGTGCGCTTTTGCTTCTT
+GAGTTGGCATTCGAATCCTCCTGTTGAAGATTAGCCGTTGAGTTTGACTGCCAGACCGGC
+GACGTATTCCCCCTGATAGCGAGCGATAGAGAGTTCCTCCTGGCTTGGTTGACGTGAACC
+GTCGCCTCCAGCGATAGTCGTTGCGCCGTAAGGCGTACCGCCGCGAACCTGGGAGACGTC
+AAACAGTTCCTGTGCGGAATAGCCTATCGGGACAATCACCATCCCATGATGGGCAAGCGT
+AGTCCAGGTCGAGGTGATGGTCTGCTCCTGGCCGCCGCCCGTTCCGGTAGAACTGAACAC
+GCCGCCGAGCTTGCCGTATAGCGCGCCGGATGCCCACAGTCCGCCGGTTTGGTCCAGGAA
+GGTACGCATCTGGCCTGACATATTGCCAAACCGGGTTGGCGTACCAAAAATAATGGCATC
+GTAATCCGCCAGCTCCTGTGGGGTGGCAACCGGTGCGTTTTGCGTTTTACCGCCAGCTTT
+TGCGAAGATTTCAGGCGGCATTGTTTCTGGCACACGCTTTATAATGACCTCTGCGCCGTC
+GACTTTCTTTGCCCCTTCCGCCACCGCGTGCGCCATGGTTTCAATGTGTCCGTACATGGA
+ATAATAGAGCACCAGAATCTTTGCCATTTGTACTACTCCTCAGATTAATCAGGTGTGTAG
+CGATTCGCTACGTCTATTTAAAGATATGCCCTCCTGTGAAGAGTGCAAATTTCAGCGCCA
+TTTCTTTGATTTATAACAATAATTAATTTGGCGACCTTTGTTGCAAAATGATACATTTTT
+AAGCGCTTTGATTTTTCCAAGTATAAGAATAACTTATTTATTTCTCATGGTTATTATTCT
+GCATATTCGGCTTCTGATGTTGCAGAATATTTCGGTAAGCGGCCTACCACGGCGTTTTTC
+ACTATGCTTAATTTTACGCGGCGTTACTGATGATATCGTTCATACGCGGCGCGAGGAGAT
+ACTCCTCATTACCTATGCAATATGATGTCTAATCTATGACGGAGGTCAGTAATGGCAAAC
+CATCGTGGCGGTTCCGGTAATTTTGCGGAAGACCGCGAAAGAGCATCAGAAGCAGGTCGT
+AAAAGTGGTCAGCACAGCGGGGGCAATTTTAAGAATGACCCGCAGCGTGCATCCGAAGCA
+GGCAAAAAAGGGGGCAAAAGCAGTAACCGTAATCGCTAGCCTGCGTCACAACAGCAAGAC
+GCTGAGCGTTTCGCGCTAAAAAGCGTCATGCGCCACCGCCGCCGGATTTCCGGCGGTTTT
+TTTGTTTATAAGCCGGATTTGGTATGCTTGCGTCCTGACGAAAAGGAGAGGGCGCATGTC
+GCAACGCACAGAGAAAAAAATCGGGAAACGTTCGCAGGCCACCGGTGCAAAACGGCAGCT
+TATCTTAACCGCCGCGCTTGCCGTTTTTTCCCAGTATGGCATTCATGGCGCGCGTCTTGA
+ACAGGTCGCCGAGCGGGCAGGCGTCTCCAAAACCAATCTGCTTTATTATTATCCCTCGAA
+AGAGGCGCTGTATGTCGCGGTAATGCGACAGATTCTGGATGTCTGGTTGGCGCCGCTCAA
+GGCGTTTCGCGCAGAATTTTCCCCTCTGGAGGCCATCAAAGAGTATATCCGTCTCAAGCT
+GGAGGTTTCGCGTGATTATCCGCAGGCGTCGCGGCTCTTCTGCATGGAGATGCTGGCGGG
+CGCGCCGCTCTTAATGGATGAACTGACCGGCGATCTAAAAGCGTTGATAGATGAAAAATC
+CGCGCTGATTGCCGGATGGGTGCACAGCGGGAAACTCGCGCCCGTTTCTCCGCATCATTT
+GATCTTCATGATTTGGGCCGCCACGCAACATTACGCCGATTTCGCCCCTCAGGTTGAAGC
+GGTAACCGGCGCGACGCTTCGCGATGAAGCCTTTTTCAACCAAACGGTCGAAAGCGTTCA
+GCGCATTATTATTGAAGGGATTCGCGTGCGTTAACCGGCTGGCGGCAGTGGGCAGCTCAA
+ATCACCCTCTTCACATTGCAGCAGCGAGGCTAAAAACGCTTCGCGTTCGTTCGTTTTATC
+GGTCAGGCACTGGCTGGCGATCATGGGTTGAACGCTGCCGCCCTCCGTACCTGAGCGAAT
+CAGCGCGCAATCGGCGTCGCGCAGGGCAATCCATGCCACCTGCGCTTTTTGCAATAGCTC
+ACGCTGCGGCGGTTGCGCACGCTTAATCGCGCTTTGATAGGTTTCGTTCAGCTTTTTATC
+TGCCGCCTGGTATTGCGCGGCGGCGCAGCGATTCATTTCCAGCTGCGTACTGGCGCTGGC
+ACACTCATCGGCCAACGCCTGACTGCTGAACAACAACGCCGCGCAGGTAAGGAAAATTCG
+TTTCATACGGTCCTCTGACGCGAGTAAAAAGGCTCCATTGACGGAGCCTTAATTAACCAC
+AGTATTAGCCAATTGTCATCAGGCTGGCATTACCGCCAGCGGCGGCAGTGTTTACGCTCA
+GCGAACGTTCAATATAGAGCCGTTCCAGCAGCATATTGCTTTCGCCGCGGGCGAACCCCT
+GTACCGACACTATCGCGCCTTCGCGGGCGGCGACGGCTTCGCACACGGTTCGCAGCTTGT
+CGGAGTCGCCGTGGAAAATCACCGCGTCAAACGGCTGCGCCATCAGCGTTTCCGCTTTCG
+CAAACTGGACACGCGCCGCGACGGCGGCGGGGAGACGTTTCGCCAGATCGCGGTGGAAGG
+CGTCGTCTGACCATAGCGCCTGACTGCCGACGGCGAGAACGGCGGCAAGCTGCGTCAACG
+CGTCCTGTTCATCATCAGCCAGGCATAACACCCGTTCACGCGGCAACAGCGTCCAGGTAT
+TACGCTCGCCGGTCGGCCCCGGTAGCAGGCGCTGCGTGCCGGCCTGCGCCAGATCGGCGA
+ATTGTCGGCAGAGCGTCTGTAGCGCCGGGCGATCCGCCGCCCATTGCGTCAGAGCGGTCA
+ACGGCGCGAGTAGCGTGGTTTTAAGCTGCGCATCCACCGGGTAACGCGCATCCTGACGAG
+TCAGCGTCGTATTGAGCGCATTGGGCGGGCGGTGTGCCAGCAGGCGGTAGAGATAGAGCG
+GCCCTCCCGCTTTTGGCCCGGTGCCGGACAGGCCTTCGCCGCCAAACGGCTGGACGCCGA
+CGACCGCGCCCACCATATTACGGTTAACGTACAGGTTGCCGACATGGGCGGAACCGGTGA
+CTTGCGCAATGGTTTCATCAATACGGGTATGTACGCCCAGCGTTAGCCCGTAGCCGGAAG
+CGTTAATCTGTTCGATAAGCTCCGCCAGTTGGTTACGGTTATAACGCACGACGTGCAGCA
+CGGGCCCGAAGACCTCTTTTTCCAGTTCTGCGAAGTTTTCCAGCTCAATAAGCGTGGGCA
+TAACAAACGTACCGGTCTGCCATTCCTGCGCGTCATCGCTGTTTTCACGCGCGGCCTGGA
+AAACCGGGCGGCCTTTGGCGCGCATCGTCTGGATATGACGTTCAATGTTGGCTTTGGCCT
+CGCTATCGATCACCGGCCCGATATCGGTCGTCAGACGGCCTGGATTCCCCATCCGACACT
+CCGCCATCGCGCCGCGTAACATTTTCAGCGTATGTTCGGCGATATCGTCCTGCAAACACA
+GCACGCGGAGCGCGGAACAGCGTTGTCCGGCGCTGTCGAAGGCGGAAGCCAGCACATCCA
+CGACCACCTGCTCGGTGAGCGCGGAAGAGTCGACAATCATAGCGTTCATACCGCCGGTTT
+CCGCAATCAACGGAATAGGGCGCCCCTGGGCGTCAAGACGCGTGGCGATGTTGCGCTGCA
+ACAACGTCGCGACCTCCGTGGAACCGGTAAACATCACGCCGCGTACACGCGCATCGGCGG
+TAAGCTGGGCGCCGACGGTTTCTCCCCGTCCCGGCAACAGTTGCACGACGCCCGGCGGTA
+CGCCCGCTTCCAGCAAAATGGCAATGCCCTGGGCGGCAATCAGCGATGTCTGCTCTGCCG
+GTTTCGCCAGAACGCTGTTACCTGCCGCCAGCGCGGCGGCGATTTGGCCAGTGAAAATGG
+CCAGCGGAAAGTTCCACGGACTGATACAGACCACCGGCCCTAACGGGCGATGCGTTTCGT
+TATCGAAATCGTCACGCACTTGACCGGCATAATAATGGAGGAAGTCTACCGCTTCGCGCA
+CTTCGGCAATGGCGTTGCTGAACGTTTTCCCCGCTTCACGCACCAACAGGCCAATCAACT
+GCTGCATTTGGTCTTCCATCAATACCGCCGCCCGCTGCAAAATAGCGGCGCGTTCTTGCG
+GCGGCGTCGCAAACCAAACCGGCGCCTGATTGACCGCGTTTTGCAACGCCTGTTCAACCT
+CGCTTTCTGTCGCTTCGCGTCCCCAGCCAACAATATCTTTCGGTTCCGCCGGGTTGATAA
+CCGGCGTCATCTCACCGTCGGCCACCGGTTGTTCCAGCACAGGTTTGGCCTGCCATTTCT
+GCATGGCGTTGCTTAACAGGGCAGAAGAAAGCGAGGCGAGGCGATGTTCATTCGCTAAAT
+CAAGTCCGGCGGAGTTTATCCGACCTTCGCCGTACAGATCGCGCGGCAGCGGAATTTTTG
+GATGCGGTATGCCAGCCTGACCTTCCTGCTGCGCCAGTTTTTCCACGGCCTCGACCGGGT
+CGGCCACCAGTTCATCGAGCGGTAGGGTGGCATCGGCGATGCGGTTGACAAAAGAGGTGT
+TGGCGCCGTTTTCCAGCAGGCGTCGTACCAGATAGGCCAGCAGGGTTTCGTGTGTTCCCA
+CCGGCGCGTAAATACGGCAGGGACGGTTAAGTTTTCCGTCCCCCACTTTACCGGTGACCT
+GTTCATACAGCGGTTCTCCCATGCCGTGCAGGCACTGGAATTCGTACTGACCCGGATAGT
+AATTTTGCCCGGCCAGATGATAAATCGCCGCCAGTGTGTGAGCGTTATGGGTCGCGAACT
+GCGGGTAGATCAGATTAGGGACGGCGAGCAGTTTTTTCGCGCAGGCCAGATAAGAGACAT
+CGGTATACACTTTGCGGGTATAAACTGGATAGCCCTCCAGCCCTTCCATTTGCGCGCGTT
+TGATCTCGCTATCCCAGTAGGCGCCTTTCACCAGACGAATCATCAGCCGACGGCGGCTAC
+GGGAGGCCAGATCGACTAAATAATCAATGACCAGCGGGCAGCGTTTCTGGTAAGCCTGAA
+TCACAAAGCCAATGCCGTTCCAGCCCGCCAGTTCGGGTTCGAAGCAGAGTTTTTCCAGCA
+GATCAAGCGAGATCTCCAGACGATCCGCCTCTTCGGCGTCGATATTGAGACCGATATCAT
+ACTGGCGCGCCAGCAGCGTCAGGGATTTCAGGCGCGGATAAAGCTCCTCCATTACCCGAT
+CGTATTGCGCGCGACTATAGCGTGGATGCAGGGCGGACAGCTTAATCGAGATGCCTGGCC
+CTTCGTAAATACCGCGACCGTTAGACGCTTTGCCGATGGCATGAATCGCTTGCTGGTAAG
+AGACCATATAGGCCTGCGCATCGGCGGCGGTTAACGCGGCTTCGCCCAGCATATCGTAAG
+AATAGCGGAACCCTTTCTCTTCCAGTTTTCGGGCATTCGCCAGCGCCTGAGCAATGGTTT
+CGCCAGTCACGAACTGCTCGCCCATTAAACGCATCGCCATGTCGACGCCTTTGCGGATTA
+ACGGTTCGCCGCTCTTGCCGATAATGCGGTTCAGCGAGCGCGAAAGATTGGCTTCGTTAT
+GCGTTGAGACCAGTCGGCCGGTAAAGAGCAGCCCCCAGGTGGCGGCGTTTACAAACAGCG
+ACGGGCTACGGCCAATATGCGACTGCCAGTTGCCATTACTGATTTTGTCGCGAATTAACG
+CATCGCGCGTAGCTTTGTCGGGAATACGCAGCAGCGCTTCCGCCAGACACATCAGCGCTA
+CGCCTTCTTGCGAAGAGAGGGAAAACTCCTGCAACAGGCCTTGCACCATACCCGCGCGAC
+CGCTGGCGGATTTTTGATTGCGCAATTTCTCCGCCAGTTGATACGCCAGTTTATGCGCCT
+GCTCAGCGACAGGCGGCGACAGGCGCGCCTGTTCCATTAGCATTGACACCGCATCGGTTT
+CCGGGCGGCGCCAGGCGGCGGTGATGGCGGCGCGAGAGACGGATTGGGGAAGAATCTGTT
+CGGCAAACTCCAGAAAGGGCTGATGCGGCTCATCCTGCGGCGCGACCGGCTCCTCGCTTT
+CATTTGCCGCGCCGGCAAACAGCGCAGGTAGCTCCGGTAGCGTATCGCTATTTTCCAGCT
+TGTCCAGATAGCTAAAGATTGCCTGTTTTATTAACCAGTGCGGCGTGCGATCGATACGCG
+ACGCGGCCATTTTGATCCGTTCGCGCGTGGCGTCGTCCAGCTTAACCCCCATCGTGGTGG
+TTCCCATACCCTCTACTCCTGTTATTCGCTCTATCTGCTAACCAATAGTTAGCGGAAAAT
+ATCCACTATATTGCAACTTTGTGCAACCGCGTTAAATGTGACCTGCGTTGCAAGCTTAAA
+AATGAATAAATTGTTAAAAAAAGAAAGTGGGAGTCTGACGGGGAAAACCATCTGGATTTA
+TTTTCTCTGCGGTAGTTAACACTTTTAAAAGGTGCAACCGCAAAAAATGTGAGAGAGTGC
+AACCTGGAGAAAAATAGTATCCCTCTGCAATCAAATTTGATGTAAATGGTGTGTTAAATC
+GATTGTGAATAACCACCGATTCCGGCAGGATACGGTCGCCCTGGTAAACATAACACCCTT
+GCCACGTTCCGGCAGGGTACAAAACGGCACGCTACGGTAGTGCCAATAAATAAATTTGGA
+GAACCTTGATGGCTATTAGCACACCGATGTTGGTGACATTCTGTGTCTATATTTTTGGCA
+TGATATTGATTGGGTTTATCGCCTGGCGCTCAACCAAAAACTTTGATGACTATATTCTTG
+GCGGTCGCAGCCTGGGGCCGTTTGTTACGGCTTTATCAGCCGGCGCGTCGGATATGAGCG
+GCTGGCTGTTAATGGGGCTGCCTGGCGCTATCTTTCTGTCGGGGATCTCTGAAAGCTGGA
+TCGCCATTGGCCTGACGTTAGGCGCATGGATTAACTGGAAGCTGGTGGCCGGGCGCCTGC
+GCGTGCATACCGAATTTAACAATAACGCGCTCACGCTGCCGGACTATTTTACCGGTCGGT
+TTGAGGATAAGAGCCGAGTCCTGCGTATTATTTCCGCGCTGGTCATTCTGCTGTTTTTCA
+CTATCTATTGCGCATCAGGTATTGTCGCTGGGGCACGACTGTTCGAAAGCACCTTCGGTA
+TGAGCTATGAAACCGCACTGTGGGCGGGGGCCGCGGCAACCATTATTTATACCTTTATCG
+GCGGGTTTCTTGCCGTTAGCTGGACGGATACCGTTCAGGCCAGCCTGATGATTTTTGCGT
+TAATCCTGACGCCGGTGATGGTTATTGTCGGCGTAGGCGGTTTTAGCGAGTCGCTGGAAG
+TGATCAAGCAAAAGAGCATCGAGAATGTCGACATGCTCAAGGGGCTGAATTTTGTCGCTA
+TTATTTCTCTGATGGGCTGGGGGCTGGGTTACTTCGGTCAGCCGCATATCCTGGCGCGCT
+TTATGGCGGCGGATTCCCATCACAGTATTGTTCATGCGCGTCGTATCAGTATGACCTGGA
+TGATTCTGTGTCTGGCGGGCGCGGTGGCGGTGGGCTTCTTTGGCATTGCGTACTTTAACA
+ATAACCCCGCGCTGGCCGGGGCGGTGAACCAAAACTCAGAACGCGTATTTATTGAACTGG
+CGCAGATCCTGTTTAACCCGTGGATTGCCGGTGTTCTGCTGTCTGCTATCCTGGCGGCGG
+TGATGTCGACGTTGAGCTGTCAGTTGCTGGTATGCTCCAGCGCGATTACGGAAGATTTAT
+ATAAGGCTTTTCTGCGTAAAAGCGCCAGCCAGCAAGAGCTGGTATGGGTAGGGCGAGTGA
+TGGTGCTGGTGGTAGCGCTGATCGCCATTGCGCTGGCGGCGAATCCTGATAACCGTGTGC
+TGGGGCTGGTGAGCTACGCCTGGGCTGGATTCGGCGCGGCATTTGGACCTGTTGTCCTGT
+TTTCTGTGATGTGGTCGCGTATGACACGTAACGGCGCGCTGGCGGGAATGATTATTGGCG
+CGGTGACGGTTATCGTCTGGAAACAATATGGCTGGCTGGATCTGTATGAGATTATCCCTG
+GCTTCATTTTCGGCAGCCTGGGGATCGTAATCTTTAGCCTGCTTGGCAAAGCGCCGACAG
+CAACGATGCAGGAACGCTTTGCAAAAGCGGACGCGCATTATCATTCCGCGCCGCCGTCGA
+AGCTACAGGCGGAATAACCGACATGTCCGATAGCATTATTGCCATCGGATATATTTTACC
+AGGCGGCGTTATACGCCTGCCTGGTCCTCTGATAAGTCCCGGACCGATTGACTGAAGGTG
+TTCAGGTAAATGAGGACGCTCTCTCAAACTATTTTTAGCCCTTGAGCGCCGTTAACGCGG
+CCGTAATACGTCTCGAGTAATCACTAACTGACCATATATGAAATCGCCTGTTAATGGTAC
+CAATAGCCTTGACGCAATAGAGTAATGACAAAAATTAAAACGAGTCAGCGTTACTGGCGT
+AAGTATGCCGCACAAAATTTTGCATAAATAATGCCGTTTTAGCGATGGGAGAGAGGACAC
+GTTAATTACTCCGTTTTAATCTTTTATATGTTGAATATTCAATGGGTTATGGGTGTTTTC
+ACCATTAATACCCATAGTAGCTAATGATTATCTTTTTTAGTCTCCTGCCAATGAAATAAT
+TGTGTAATCTTTCTGTAAGAGACTGACAATGACGCAATAATGTTTGGTTAATGTTTGGTG
+AATATATTGTTGCATTATTGATGTTTTGTGTTGTACTTAGTAGTAATAGCGGTAGTTCCC
+CGGCAGTGATGGTCACTCACTATGGAGATCGCGAATGGTAATGTCCGCACCAGGACACAT
+TGTTTACAGTAGTTACAACACCCTGTACGGACATTCTCTCTCCGGTGGTGGTCTTGTCAT
+CTTAAAAGCTCTCATCATTTCCCTTACTGTCCATACCCATGACGCCATATGTGGTGCGCG
+TAGCCGTGTGTGGCGTCGTTTCAAAAAGCAAGCTAAGGCTTACAAGGAAGCCAACCCTCA
+GATGTGTGTGCGCATAATCGCGTTCAAGAGAACGCGGGTGATGTATACCTACAACTCAAG
+GTGCTATCCATGGGAAGACAAAAAGCAGTGATCAAAGCTCGTCGTGAAGCAAAGCGTGTG
+TTGAGACGAGATTCGCGTAGTCATAAGCAACGTGAAGAAGAATCGGTCACGTCACTGGTA
+CAGATGGGCGGAGTAGAAGCCATTGGCATGGCGCGCGATAGTCGCGATACCTCTCCTGTT
+AAGGCGCGAAATGAAGCACAGGCGCATTATCTGAACGCTATCGACAGTAAACAGCTTATT
+TTTGCGACCGGCGAAGCCGGCTGCGGAAAAACATGGATCAGTGCGGCAAAGGCGGCAGAA
+GCATTGATTCATAAGGACGTCGAGAGGATCATTGTGACGCGTCCGGTATTGCAGGCTGAT
+GAAGATCTTGGTTTTTTGCCCGGTGATATCGCTGAAAAATTCGCGCCTTATTTTCGTCCC
+GTCTACGATGTCCTGCTTAAACGGTTGGGCGCGTCCTTTATGCAATATTGTTTGCGCCCG
+GAAATCGGTAAGGTAGAAATTGCCCCGTTCGCCTATATGCGTGGGCGTACTTTTGAAAAT
+GCGGTCGTGATCCTCGACGAGGCGCAAAATGTGACTGCGGCGCAAATGAAAATGTTTTTG
+ACGCGATTAGGCGAAAATGTCACGGTCATTGTCAATGGCGATATTACGCAATGCGACCTG
+CCGCGCGGTGTGCGTTCCGGGTTGAGTGATGCGTTGGAACGCTTTGAAGAAGATGAAATG
+GTGGGGATTGTGCATTTCAACAAAGACGACTGCGTGCGCTCGGCGCTTTGTCAGCGAACG
+CTCCACGCATACAGCTAATATAGCATTGACTTTCAGAGCCCGGGAGACCGGGCTTTGTTG
+TCTATAAAGCGTCCAGCAGACTCATGGACAAAAAAGGAAAATGACGCCTGTACGTGAAGG
+GAATTATTTTGTCATGTCCAGGGCATTCATTGTCCGTAATTTGCTTTCTCGGGCCTGTTC
+CGGCGAGGACTGTACAAGAAGGGTATAGAGCAGGTCAAAGACGAAAAGCTGCGCGGCTTT
+CGTACCGATCGAGTCACCCTGCAACATTCCTTGCCGATTACCATTGATCAGGCAAAAATC
+GGCCTCTTCACATAATGGAGAACCCAGATTATGGGTAATGGCGACTGTGGTGGCGCCAGC
+CTGTCGGGCCAATCGGAGTGAATGCACTGTTTCTGGCGATGTGCCCGAGTGACTGACACC
+CATCGCGACATCGCCTGCTTTCAATAGCGTAGCCTGCATGTACATAAAATGGTTATTGCT
+TACCGCATCGCCCCGTAAACCCATACGCATTAGCTTGTGTTTCATATCCAGCGCCGTGAT
+CCCCGATGAGCCCACACCAAACATATAAACTGAGTGACAGTGACGTAGGGCGTCCACGAC
+ACCGAGAACCTGTTGCATATCCAGCAGATTTAGCGTTTCAGATAATACATTACTAATGGT
+GTTCTGCAATTTTAAACCAATCGCGTGGGCATCGTCGGATTCGCTAACTTCGGCATCCAG
+TAGAGGACTACTGTCATCAGACTCGGTAGTGGCAAGTTCAATGGCCAGGTCCATTTTAAA
+ATCCTGAAAACCTTTATAGCCCAGGGTGCGACAAAAGCGAATAACCGTGGCTTCTCCGGC
+CTGTGTGTCGCGCGACAAATCCGCAATAGATGACTGTGTCACCTGTCTGGGGAAGGCTAA
+AATATATTGCGCAATACGCTGCGAGGCACGTGTCAGGCTTTTTTGCATAGCACCCAGAGT
+GTCAAGGATTTTTCCGGGTTTCAGACGTGGGGGTTGAGGCTCCATATAGTTCCTGCTCTT
+GAGGGCTGATTGCGGCACAAACCCTGCAATATCGAACAGAGCAGAGCCTATCAAGTCTGC
+GGCATGAAAAAAAGCGCGATGCAAGTAAAGGAGGGGGAATATTTACATCGCGTTGCCAAC
+TTATGACAGAACATCACTGGACAGTAATCTGTTTGCTCTTACGGTGTTTATAGCGCGCCA
+TCTGTCGGATGGTTTATATCTCGCCCGGTATTGTCGCCCCGCGCGTTGGCGTCACCGTGT
+GCTGTGTCGGTATAGCGTGGTCTCATGAAATCATAATGTCACCTTTGGTTCAGGTTTTTC
+ATCCAGCGTCAATGGCGGTGCCGGGGCAAATAACGGGGCGAAAATAACGCCGCTGATCAC
+CACGCTTAGCGAGCCAATGACCCCATAAAAGAAGAAGTTAAGGTCAGTGGCATAGCGTGT
+GCCCAGCACGGTAATGACGCTCATAATAATTCCTAAAACCGCACTCCCGGCATTTGCTCG
+TTTAAAGAAAATGCCCAGCATCAACAGACCGGTCATTGGCCCTCCCATCAGACCTATCAG
+ACTATTAAATGCATCCCAGATCTCTGATTCATCGGCCATGACCAGCCATACCGAGGCCGC
+GCTACTTATCAGGCCCGCGACCAGAATAACTAACTTAGCTATTTTCATACGGTTTTCTGG
+CGTTCCTTTTTTATGACTCAACCGCTGATAGATATCGGAATTAAAACAACTGGAAATGCT
+GTTTAAGCTGCTGGAGATGCTCGACTGCGCGGCAGCGAAAATAGCGGAGATTATCAACCC
+TGCAATGCCGACTGGCATTTCCGTGACCACGAATAAGGGCAAAATGCCGCCAGTGTTGAA
+TCCCGCCGGTAATAATTGTGGCTGTTGCTGATAGTAGACAAATAATGCCGAGCCGATAGC
+AAAAAAGAAAACAGGGATCACCGCAACCAGTTTGGCATTTGTAAGTAATGTTTTCTTCGT
+TTCCTCTATGGAGTCAGTCACCATATAGCGTTGGACCACATCCTGACTGGCAGTAAATTG
+CTGAATATTGGCAAACAGAAACCCAATCATCAATACAGGTACTGTGCTTTCCGTCCAGCT
+CCAGTGGAACTGCGTAGCCGGCAAGAATTTATCCGCCTGCTGCGTCACCGTAAAAATTTC
+ACCAATGCCGCCCTGGACTTTCAGACATATCACTATAAAAATCAGTATCGCGCTGCCAGA
+AAGTAAGAGACCTTGAATAACCTCAGTCCATATTACTCCTTCAATTCCCCCCCATCCAGG
+TATAAATGATACACATCACACCAATCAACAGTACCAAAATCACCGGGTCTATAGCGATGA
+AGGGGCGCAAGGCCAGCACGGCGAGGAAAGTGATAATGGCGATACGTCCAATATGAAACA
+ACATAAATGACATGCTGGCGACCAGACGGCAGCGCACATCGAACCGTGCTTCGAGATATT
+CATAGGCTGATGTGACTTTCACTTTCCGAAAAAACGGAATATAGAAATAAAAAACCAGCG
+GTAAAATTGCGATAGCCAGATCCTGACCAATGATAAACGTCCAGTCGGAAGTAAACGCTT
+TGGCAGGAATTGACATAAATGCAATTGAGCTTAACGTAGTAGCAAATACACTGACCCCAG
+CCGCCCAACCAGGAACCCGGCCACCACCGCGAAAATAATCGTCTGCTGTTTTTTGCCGTC
+TGGAAAAATAGACACCGACTACCATCATGGCCAGGAGGTAGCCAAATAATACAAAATAAT
+TAACGATGCCGAAAGAATGTGCAATCATAGTTCTTTCCTGCTTATGGTTTTGAGTAGCGT
+TGCGGTCATCGTCTGTGTATTTTTATCTTCCCATCATTCAGACGATACGATATTCAGATC
+AAGCAATAGTTTTTGTTAATCTCAATGACGCTAATCATGAGATGTAAAAGGCAGAGCATT
+TATGCTCCACCAATGGTGATGCCCAGACGTATGTCCTGCCGGATACCTGAAATAGCAGCT
+ATCCGATATTGCGTTCAAACAGGCTTCAGGCCTGGGTATCGTATTTGCCGATAGCATTCT
+TAACGTCGGATTATTCTCTGAGACATAAATATCAATAGTAAGCGTGTTCATTTTCTTTTC
+CTGTTCAGCGTTTTACTGCGTGACTGAACCACTGACAGATATGCTCGATACGGGTGATAG
+CGGAACCAACGGTAACTGCCCAGGCACCATGCTCAATAGCATTGGCCGCCAGTGCAGGCG
+TGTTATAGCGCCCCTCGGCAATAACACGACAACCTGCATGACTCAGTTGTGTCACCATTG
+CCAAATCTGGCTCAACCGGCGTGATGGGACCGGTATAGCCAGACAGTGTTGTACCAATGA
+ATTCGATTCCTTTCTGATGGCAACTTATGCCTTCATTCACGGTTGAACAGTCTGCCATCG
+CCAGTAATCCATGCAGGCGAATACGTGTCAGTAAACTATCAATATCAACCGGGCGAGAGC
+GGAATGAGGCATCAAAAGCGATAATATCGGCACCTGCCTGCGCCAGGGCGTCAACATCCT
+GTAAATATGGAGTGATACGGACTGGCGACCCTGTAAGGTCACGTTTAATTATCCCAATAA
+TAGGAACAGAAAGATGGGGACGAACAGTCCGCAGATTCTCAATGCCTTCAATGCGCACAG
+CGACCGCACCCGCCGAAGCCGCTGCCTGTGCCATTGCAGCCACAATTTCAGGTTTATCCA
+TAGGGCTGCCTGGTACCGGTTGGCATGAGACAATCAGCCCACCGTTTTCGTGTACACTTT
+GTTCCAGCCTGGCTAATAGTGACATCCAGTTCCGCCTTATATATTTTGAAGTTTTACTCC
+GTTTTATATTATGTTGTGGAGTGTTGCTGCATCAAGCAAAAAGATAGAAAAATGTGAACA
+CAGTCATAAGGTATGTTTGTCATTCAATTACTGCGCCAGCGGATTTGAGGCTATAACCTG
+AAGCTACAAGACAAATACAATTCATTCTGACGGCAGCATGCTGTATTTTATTAACTGCTT
+CCGGCATAAAGATAAAATGCTCAGAAGGAGCTTATACGCCACGGGATAGCCAGTATGAAA
+TGCATCACATAATTCTTGTTGTATTTATTCAGAATGCAATCACTAATGAGTTTGCCCATA
+ACAGGTCACCCATAATCACTTCTAACATCACCATAGTGTGCTTTTACCTCGCACATGGTA
+ACCCCATGTAATTATTTTTAGCGCTTGGTCACATTTTGTCATTTTCATTGTTGAAATTAT
+GCACCATAAGATCACTAATGATGAAGCTTTACTCCAGTTGTATTTCTTCGCATGGGGATG
+CAGATGAAAAATTTTAAGAAAATGATGACGCTAATGGCGCTATGTTTATCAGTTGCTATC
+ACCACATCAGGATATGCAACCACGCTTCCTGATATACCAGAACCACTGAAAAATGGTACT
+GGCGCTATTGATAATAATGGCGTGATTTATGTCGGCTTAGGTACCGCAGGGACATCCTGG
+TATAAAATTGATCTTAAAAAGCAACATAAAGACTGGGAGCGTATAAAGTCGTTTCCTGGT
+GGAGCTCGTGAGCAATCCGTGTCGGTATTTTTAAATGATAAGCTGTATGTTTTTGGTGGC
+GTAGGGAAAAAAAACAGTGAATCACCGTTGCAGGTTTATAGCGATGTGTACAAATACTCA
+CCGGTGAAAAATACATGGCAAAAAGTTGATACTATATCTCCAGTTGGATTAACAGGGCAT
+ACGGGAGTAAAATTAAACGAAACGATGGTACTTATTACCGGAGGGGTTAATGAGCATATC
+TTTGATAAGTATTTTATTGATATAGCGGCTGCGGATGAAAGTGAAAAAAATAAAGTCATC
+TATAATTATTTTAATAAACCTGCCAAAGATTATTTTTTTAATAAAATCGTATTTATCTAC
+AATGCTAAAGAGAACACATGGAAGAATGCCGGTGAGCTGCCAGGCGCGGGGACGGCAGGA
+TCGTCATCGGTAATGGAAAATAATTTCTTGATGCTGATTAATGGTGAGCTCAAACCGGGT
+TTACGTACCGATGTGATTTACCGCGCCATGTGGGATAACGATAAGCTAACATGGTTGAAG
+AACAGCCAGTTACCGCCATCGCCTGGAGAACAACAGCAGGAAGGGTTGGCCGGAGCATTT
+TCGGGCTATAGCCACGGTGTCCTGCTTGTCGGTGGTGGCGCGAATTTTCCGGGAGCAAAA
+CAAAATTATACTAATGGAAAGTTTTATTCCCACGAAGGGATAAATAAAAAATGGCGAGAT
+GAAGTCTATGGTTTGATTAATGGCCATTGGCAATATATGGGTAAAATGAAACAACCTCTC
+GGCTATGGTGTATCAGTAAGTTATGGTGATGAAGTTTTCCTTATTGGTGGTGAAAATGCT
+AAAGGGAAACCTGTTTCGTCTGTAACCTCCTTTACCATGCGTGATGGTAATTTATTAATA
+AAATAATTTTTTAAATACAAAAATAAAGTTAATTGATAAGCGGAGTATTTTATGAAAATC
+AACAGATATCTTCTGGGTATGGTTTCGTTTATAGCATTTTCATCATATCTACAAGCGGCA
+ACCCTTGATTATCGGCATGAATATGCTGATAGAACCAGAATTAATAAAGACCGTATTGCT
+ATAATTGAAAAGCTTCCTAACGGCATTGGTTTTTATGTCGATGCCAGCGTTAAATCGGGA
+GGAGTAGATGGTGAGCAGGATAAGCATTTAAGCGATCTCGTCGCAAACGCTATAGAACTG
+GGCGTAAGTTATAATTATAAAGTTACGGACCATTTTGTTTTGCAGCCTGGATTTATATTT
+GAAAGCGGTCCAGACACTTCAATTTATAAGCCTTATTTAAGGGCGCAATATAATTTTGAT
+TCTGGTGTTTATATGGCTGGTCGTTACCGTTATGACTATGCAAGGAAGACAGCTAACTAT
+AATGATGATGAGAAAACGAATAGATTTGATACTTATATAGGTTATGTTTTTGATGAGTTG
+AAATTGGAATATAAATTTACCTGGATGGATAGCGATCAAATTAAATTTGATAACAAAAAA
+ACAAACTATGAACATAATGTGGCTTTAGCCTGGAAACTGAATAAGTCATTTACACCATAC
+GTTGAGGTCGGAAATGTAGCGGTGAGAAATAATACCGATGAGAGACAGACCCGTTATCGC
+GTTGGATTACAATACCACTTTTGAGAAAGGTTAAAGAGTTACTGTACTAATCTTTGCTTA
+GTATTCATATCGATAATCTTATAGCCCGTAGCTACGTTACAGAACGTTAGACTTTGTCTT
+GAGTATTCACGTCCTTAACGTAGCTACGAACAAGGATGATAAACAATGAATATACGCCTT
+ACATAGCTACGATCTCAGGCGGTTGTCGGAAAGTGCCGGTTGATAGTGTCTTATTCGGCA
+ATTGATATGACTTAAAAATTAATTCCGTAAGCATTTCAGACGGTAACAGCAAATAAGGGT
+TTTATTGTGATAGCAAAATTCTTCCCGTGGTATAGCGAGATAACACGTCCACAAAAAAAT
+GCTTTATTTTCAGCATGGCTGGGTTACGTTTTTGATGGCTTCGACTTTATGCTGATTTTC
+TACATTATGTATCTGATCAAGGCTGACTTAGGATTGACAGATATGGAGGGCGCATTCCTT
+GCCACAGCGGCCTTTATTGGGCGACCATTTGGCGGGGCGCTATTTGGTCTGCTGGCAGAC
+AAATTTGGCCGTAAGCCGTTAATGATGTGGTCGATAGTTGCCTATTCTGTAGGTACAGGG
+TTAAGTGGCCTGGCTTCCGGTGTAATTATGCTGACGCTTAGTCGTTTTATTGTCGGTATG
+GGGATGGCGGGGAAGTATGCTTGCGCTTCTACTTATGCCGTGGAAAGTTGGCCAAAGCAT
+TTAAAATCTAAAGCGAGCGCATTTCTGGTTTCAGGTTTCGGTATTGGTAACATCATAGCA
+GCCTATTTTATGCCGTCATTTGCCGAAGCGTATGGTTGGCGTGCTGCTTTTTTTGTCGGT
+TTGCTACCCGTTCTTTTAGTAATCTACATCCGGGCCAGGGCTCCTGAATCTAAAGAGTGG
+GAAGAAGCCAAACTCAGTGGTCTCGGAAAGCATTCACAAAGTGCCTGGTCAGTTTTCTCT
+TTGTCAATGAAAGGGCTATTTAATCGAGCTCAATTTCCACTGACATTATGTGTATTTATT
+GTTCTGTTCTCTATTTTCGGCGCAAACTGGCCGATCTTTGGTCTACTGCCTACATATTTG
+GCGGGAGAGGGCTTTGATACGGGCGTGGTCTCTAATTTAATGACGGCGGCGGCATTCGGC
+ACTGTATTGGGAAATATCGTTTGGGGTCTGTGCGCAGATAGAATTGGTTTGAAGAAAACG
+TTCAGCATTGGTCTTCTCATGTCCTTTTTATTCATTTTCCCGTTATTCAGAATTCCGCAA
+GATAATTATTTACTGCTGGGCGCATGTTTATTCGGTTTAATGGCGACTAACGTAGGTGTT
+GGCGGGCTGGTTCCCAAATTTCTCTACGACTACTTTCCTCTTGAGGTTCGTGGTTTGGGT
+ACCGGGCTTATTTATAATCTTGCTGCGACATCAGGCACATTCAATTCAATGGCGGCGACC
+TGGCTTGGAATAACAATGGGGCTAGGCGCTGCGCTAACGTTCATTGTTGCTTTCTGGACC
+GCAACAATTCTACTCATTATTGGCCTATCCATTCCGGATAGACTAAAAGCACGTCGTGAA
+AGGTTTCAGTCAACAAAAGAATTTTAATAGAGGATAAATGATGACGAAATACGGTGTTAT
+AGGTACAGGTTATTTTGGCGCTGAACTGGCGCGATTTATGTCTAAGGTTGAAGGGGCGAA
+AATCACTGCGATTTACGATCCGGTAAATGCGGCTCCGATAGCGAAAGAGCTGAACTGTGT
+CGCCACTTCAACGATGGAGGCGCTTTGTACCCATCCTGATGTGGATTGCGTAATTATTGC
+TTCACCAAATTACTTACATAAAGCGCCGGTCATTGCGGCGGCTAAAGCGGGTAAACACGT
+GTTTTGTGAAAAACCTATCGCCTTAAATTACCAGGATTGTAAGGATATGGTTGATGCCTG
+CAAAGAAGCTGGTGTTACCTTTATGGCGGGTCACGTTATGAACTTTTTTCACGGGGTTCG
+CCACGCTAAAGCGCTCATCAAAGCCGGTGAAATCGGTGAAGTTACACAAGTTCACACTAA
+ACGTAATGGTTTTGAAGACGTGCAGGATGAGATCTCATGGAAGAAGATTCGCGCAAAGTC
+AGGTGGGCATCTGTACCATCACATTCACGAGCTAGATTGTACACTGTTCATCATGGATGA
+AACCCCATCCCTGGTTTCAATGGCGGCGGGGAATGTTGCGCACAAAGGTGAAAAATTTGG
+TGATGAAGATGATGTTGTCCTAATCACCCTTGAGTTTGAAAGCGGTCGTTTCGCGACACT
+TCAGTGGGGATCATCGTTCCACTACCCTGAGCACTATGTATTAATTGAGGGCACGACAGG
+TGCAATTCTCATTGATATGCAAAACACGGCTGGTTATCTAATAAAAGCGGGCAAAAAAAC
+ACACTTTCTTGTGCATGAAAGCCAGGCGGAGGATGATGATCGTCGCAACGGTAACATATC
+CAGCGAGATGGATGGCGCAATCGCTTATGGTAAACCCGGTAAACGTACGCCGATGTGGCT
+CTCATCAATTATGAAACTGGAGATGCAGTACTTGCATGATGTGATAAACGGTCTGGAGCC
+AGGCGAGGAGTTTGCTAAATTGCTAACGGGAGAAGCGGCGACAAATGCCATTGCTACCGC
+TGATGCTGCGACGCTTTCTTCAAACGAGGGGCGCAAAGTTAAACTCACTGAAATTCTTGG
+CTAAAATTTAAAGCCGGATGGTGGTGTTATTGGCCGGTGGCGCTGCGCTTATGTAGACTG
+GATAAGGCGCCCGTGAACTGTGCCGCCATCCGGCAATGGACGGGGGCTTAATGCGAAAAA
+AAGCCCGTACATTCGTACGAGCTCTTTCTTAAATATGGCGGTGAGGGGGGGATTGACTCG
+CTGCGCTCGCCCTTCGGGCAGCCCGTTCGCTGCGCGCCCGGTCTGTCCAACTGGCTGCGC
+CAGTTGTCGAACCCCGGTCGGTGGTTCTCATCCCCCCTTGGTTTGGGGGATACATATAAG
+CAAAAAGCCTGTACTTCTGTACAGGCTCTCAACTTGAAGATGGCGGTGAGGGGGGGATTC
+GAACCCCCGATACGTTGCCGTATACACACTTTCCAGGCGTGCTCCTTCAGCCACTCGGAC
+ACCTCACCAAATTGTCGCTCCAGCATTACTGGAACGGGCGCTAATGTAGGGAAATATCCT
+TTCTACGTCAATCAACTTTTTTAAAAAAAAGCGCTTTTATACAAACTTCCATCAATCTGT
+GGCTTTAATAAGCGAAAACTGCTTTTTTTGCCCGCGCCGGGAAATTTGCTATGCTGCACA
+TCCCGTTGAAAACGCTGATAACAGGCGCAATCACATTCCGCACAATACTGCTCAGGAGAT
+AACATGGAGATAATTTTTTATCACCCGACATTTAACGCCGCCTGGTGGGTAAATGCGCTG
+GAGAAGGCTCTCCCACATGCGCGCGTTCGTGAATGGAAGGTCGGTGATAACAACCCCGCA
+GACTATGCGCTTGTATGGCAGCCCCCGGTTGAAATGCTGGCCGGAAGACGCTTAAAAGCC
+GTCTTTGTGCTGGGCGCGGGGGTGGATGCAATTCTGAGTAAATTAAATGCGCATCCGGAA
+ATGCTGGACGCCTCCATTCCTCTATTCCGTCTGGAAGATACCGGAATGGGCCTGCAAATG
+CAGGAGTATGCCGCCAGCCAGGTATTACACTGGTTCCGTCGTTTCGATGATTATCAGGCG
+CTGAAAAATCAGGCGCTATGGAAACCGTTGCCGGAATATACCCGCGAAGAGTTTAGCGTC
+GGTATCATAGGCGCAGGGGTACTGGGCGCAAAAGTGGCAGAAAGTCTACAGGCGTGGGGG
+TTCCCGTTACGTTGCTGGAGTCGTAGCCGCAAATCCTGGCCTGGCGTGGAAAGTTATGTA
+GGGCGTGAAGAACTGCGCGCTTTCCTGAACCAGACGCGGGTGCTGATTAATCTGCTGCCG
+AATACGGCCCAAACGGTAGGAATTATTAATAGCGAATTGTTGGATCAATTGCCGGATGGC
+GCTTACGTGCTGAATCTCGCGCGCGGCGTTCATGTTCAGGAGGCGGATCTGCTGGCTGCG
+CTTGATAGCGGTAAGCTAAAAGGCGCGATGTTGGATGTCTTTAGCCAGGAACCGTTACCG
+CAGGAAAGTCCATTATGGCGCCATCCGCGAGTCGCCATGACGCCGCACATTGCGGCAGTC
+ACCCGTCCGGCGGAAGCCATCGATTATATTAGCCGCACCATTACCCAGCTGGAGAAGGGA
+GAGCCGGTGACGGGGCAGGTGGATCGGGCGAGAGGATATTGGTATCAACCCGGCGCGGGC
+CGGGTTTCGCTAAAAAACGCTGGCGATACCTGCTATCCTTGGCGGAAATGACTACAGGAG
+AGAGCAATGTATCCCGTTGACCTGCATATGCATACCGTCGCGAGCACTCATGCCTACAGT
+ACTCTGAGCGATTATATCGCGGAAGCCAAACGCAAAGGCATGAAACTTTTTGCGATTACC
+GATCATGGTCCGGACATGGAAGATGCGCCGCATCACTGGCAGTTTATTAACATGCGCATC
+TGGCCGCGTCTGGTTGACGGCGTGGGGATACTGCGTGGCATGGAGGCGAATATCAAGAAT
+ATTAACGGTGAAATTGATTGTTCCGGAAAGATGTTCGACTCGCTGGATCTGATTATCGCA
+GGCTTTCATGAGCCCGTTTTTGCGCCGCATGATAAAGAAACGAATACTCAGGCGATGATC
+GCGACCATCGCCAGCGGCAAGGTGCATATAATTAGTCACCCGGGAAATCCAAAGTATCCA
+GTGGAGGTTAAAGCCATCGCGCAGGCGGCGGCGAAACACCAGGTAGCGCTGGAAATCAAC
+AACTCTTCTTTTCTGCATTCGCGTAAAGGAAGCGAAGATAAGTGCCGCGCGGTCGCTGCC
+GCCGTACGCGATGCGGGAGGCTGGGTAGCGTTAGGCTCTGAGTCCCATACGGCCTTTACG
+CTTGGCGATTTCACCGAATGCCGGAAAATTCTGGATGCGGTGAATTTTCCGGAAGATCGA
+ATCCTGAACGTCTCTCCGCAGCGCTTACTGGCCTTTCTCGAGTCACGCGGTATGGCGCCT
+GTACCGGAATTTGCCGAACTTTAATCGTTATTTACGGGAAGGTATCAATGAATGAGTTTT
+CAATCCTGTGCCGTGTGCTGGGATCGTTGTTTTACCGCCAAGCGCAAGATCCTTTACTGG
+TTCCGCTGTTTACGTTAATCCGTGAAGGTAAACTGGCGGCAGACTGGCCGCTGGAGCAGG
+ATGACATGCTGGCGCGTTTACAGAAAAGCTGCGATATCACGGAGATTTCCACTGATTACA
+ATGCGTTATTTGTTGGGGAAGAGTGCGCGGTAGCGCCATACGGCAGTGCGTGGGTCGAAG
+GCGCGGAAGAGTCTGAGGTGCGCGCTTTTTTAACGTCGCGAGGGATGCCGCTGGCCGATA
+CGCCTGCCGATCACATTGGCACTTTATTGCTCGCGGCCTCCGGGCTGGAAGATCAGTCTG
+CCGAAGATGAAAGTGAAGCGCTGGAAACCTTATTTGCCGATGATCTGCTTCCCTGGTGCA
+ATACCTTCCTCGGTAAAGTTGAAGCCCATGCCGTTACGCCAGTCTGGCGCACTCTGGCGC
+CGCTAACGCGTGATGCGATAGGGGCCATGTGGGATGAACTTGAGGAAGAAGATGAAGAAT
+AATGTGATGTAAATCACCATTAACTGCAACGGGTTTTGCATGATTGCATAAAATGTGTGC
+GTGATCTCATTAATGTGCCGCTTTTCTGTTATGATGCGCGCGATGAACATACTTCTTTCT
+ATTGCTATCACTACGGGCATCCTTTCTGGAATATGGGGATGGGTGGCCGTCTCCCTGGGG
+TTACTAAGCTGGGCCGGTTTTTTAGGCTGTACGGCTTATTTGGCCTGTCCGCAGGGCGGC
+TTTAAGGGATTGTTGATTTCCGCCTGTACGCTGTTAAGCGGGATGGTGTGGGCGCTGGTC
+ATTATTCACGGTAGCGCGTTGGCGCCGCATCTGGAAATTGTGAGTTACGTGTTGACGGGG
+ATCGTGGCATTCCTGATGTGTATCCAGGCAAAGCAGCTATTGCTTTCTTTTGTTCCGGGA
+ACATTTATCGGCGCCTGCGCGACATTTGCAGGGCAGGGTGAGTGGCGGTTGGTATTACCG
+TCGCTGGCGCTGGGGCTAATCTTTGGCTATGCCATGAAAAAGAGTGGGCTATGGCTGGCA
+TCACGCCGCGAGCAACATTCAGCGAATACGGCGGTCACAAAGTAAAAAAGCGTGGGGTTT
+TCCCCACGCTTTGTCGTATTCATCAGGATTCTGGCGGTACTGACAGCTCACGGTATTTCA
+CCAGAATATCATTTTGCCTGTCCGCTTTATTCTGCAAATCCGACAGTCCGCGATCGATAC
+CATCATTAATGAGGAAGATAACGCCGGTTTCAATGGCTGACGTCAGACACAGCATCACCG
+GTTCGTTCGAGGTATAGCCGATTTCGCCTTCCAGTAAGCGCGGGTAATCAATAAAACGGA
+ACACGCCTGCCTGTACTTCATAGGAAAGGATCGTTTTACTGGTGTTCACCGAAGAAAGGA
+TCTCGCCCGTACTGACGTTAACCACGCGCAGGTTGACAGCAGTCTGATCCAGCTGATACT
+GCGTATCGGCGCCAATACCGAAATATCTTGCGCCGACCCCGGCGGATTTGACGTTACTTT
+CATAACCAATAATAGAACCTTCCACCATAATATTTGCCGCCGTCAACGACTGAAGCGGGA
+TACGGTTATTCATCGCCACGGTGCCGTTTTCCTGGGCTGCGGGAATAATTTTCCGTTCAT
+TCAAAAGATTCTGTAAGCCTTGTCGTTCTAGTGGGATAAACGAGCGCGAATCTTTCAGCG
+CGGTGACCAACATAGCGGTGGCGCTCTGCGGCACAGCCGTGGAAAAGTTACTTGCCGGGT
+AAGGTTTAAATTGGCCCGTTTCATCCTGAATGTTATATACCGAAACAAAGATCTTACCGG
+TGGGAGCAGGTAAGTGCGTCAAATCTTTGTAACTTTGTGCGGGGGGCATTAATGTCGGTT
+TCGCAGCTTGTTTCGGCGGGGCAGTTAAGCATCCGCTCAACGATAAAACGGCAACCAAAA
+TAAGTAAGCGCGGCATGATTTATATCCTTTAGTGACTGTAGGTTAAAAATCGGTTGACTG
+AGTTTGTAAACCTGACACTTCGATGGTCGAGGTTCTTCCCGGTTTTCTGTCCGTGACGTT
+GAGCTGGAGCTGTCCGTCGCGATTAGCGATATCGATAATAAGATCATTGGTCACCATACG
+TCCTGGTTTTCCGGTATTAATATTGGTCAACAAGCCGCCCAGAATTTGCGATTGAATAGC
+CTGCGTAAAGTTATCCAACGCTGAGGGGGTCTCGATACCAAGATCGTTATCATAAGCGGG
+GTCTTTATATGAATTTTGCGCCTGGGCGCTATTCAATAAAAGGGAACCGTTATTGGGGTT
+TCCACCAAAGTTAGGATTACGGAACTGGAACGTCATATTTCGAGCCCAGGTTAATGGCGA
+AAAAAGCATGAGCAGCACTACTGCATGTTTAACACGCATGAGAGCCTCCGGATAAAAATC
+ATGTTTTAGAATTCATCACGCGCTAAATCACTCGTACTTAAGAGCGTTTGATCTATTTGT
+CGGCGATTTAATGCTTCCTCTGTTTGCGCTAATGCGAAGACGACGGTTTTCTCGAAGTCT
+CTTTTCATTGGAAATAAAAAGGTCTGGAAAATAACGTCCTGGTTTACCGTTATGGTGATC
+CAGCTTCCCCAACGCGCACTGGGTCTTTCATTAATGGTCAGGTTGCCGGTGTATTCGCTT
+TCCCATTTGTCGCTGAATGCACGATAGAATTCATGTCCTATGGAAGAGACGGTATGGTCG
+GTTAACAATCCGGGAACCTCGACTTCAACTTCATTGGCATGGAGGTTTCCGGTAGCGAAC
+AGTAACTCTGCTGCTACAATCCAGGTCAGATAGCGTTTCATGGCCTTACCGCCTGAGATT
+ATCGTTTGCTCATGAAACTGCCTGGGTGCGATTTTTGACAGGTATCTTTTTGAAAAGATT
+ATAAAGATGTGTCTTAACCGTATTCTCGCTGATAAATAGCGGCCTGGCGATTTCATTATT
+AGAGGCACCAATACGTAACTTATTGAGGATCTCTTTTTCGCGATGAGTGAGTAATGCGGA
+CTCGGTGCTGTTGTAGCGGTAATTTCCTGAGTGTGTAATCAGGTAACTGGCTAATTTTTG
+TGAAAAATAGCATTCGCCCCGCAGAATACCCTGTAATCCGCGGACCACGTGTTCCTGGTC
+TTCAGTGGCGTAAAACACGCCGTTAATATGAGGCCAGTTTTGAATTTCACGGTAGGGATA
+ATCGTCAGGGGTATTTAACAATAATGTTTTTATATTATTGTGTTTGCGGCTTAAATTATC
+CTGCCAATAGTGGATAAGCTTCTTATCCGCTTCCATCATATGCATTAAAACAATGCAACC
+GGCTGAGATATCTTCCAGAGAACGTTGAATATTATGCAGTTGTCCGGTTATGGCCAGCGA
+TTGCTTTAAATGTTGCAATAATGCCGTAGCTTGCAGAGATGGCTTTGTGATCAACAATAG
+TGTGTGACCATGACTACTATGGACTTCATTAAACATGATGAGACTCCACTTTTTTTAATC
+GCACATCTGACAGCTGCCCCCATAAAATAAAGGCACCAGAAGTACTGACAGATGTTGCAC
+TGCTGTGGGTTGAAATAGCCCATTATCCAGAAAGAGAAAAAGATTTACGAAAATACTTTT
+AACTGTTTTCAATCTAGCCATTACAAATCTTAAAGCAAGTGGTAAACTTGTAACAAGATG
+TAAAAATATATATTAAAATGTTGTTTTTGGGTTTTTTTGAAGTTTAGATTTGATAGTAAA
+GTTGTACATTTCGCTGTTATTGCATAGATTTAAAAAATCATGCAAATTATAATAATTCAT
+TGATTTTTAATCATTTTAATTATTGTATGTCATGTTTTGATGTTATTTTTTCTTAAAATT
+TGAGACGTGGCATTAACCTGGACAGCACAAAGACAAAAAAAGACGAAGTGTGTCACGTCT
+TGTGCGTATTGCCCCCCATGGGAAGCATAAGAACATCCCCAGGGCGGCATAACACACACC
+AACACTTCATTTTTTAGGTGCGCGATACACTATCTTCTGTGGCCAAAAATCAATTATAAA
+AAATCACATGGCTATCGTTTTATTAGCACTTTGGTATGAGCGTAAATAACAAAATACCAC
+GCGTGGGTGAGTTATTAAAAATGTTTCCACGGACATACTCTGCATCGTAACGACGCGTTA
+ACAAAAAACGCATGTCGCTAACAAGGTAATAGATAATTTTCGCTATGTACGACCAGGTCC
+AGGGTGACAGCATGAAAAACAAATTGTTATTTATGATGTTGGCAATACTGGGTGCGCCTG
+GGATTGCAACCGCGACAAATTATGATCTGGCTCGTTCAGAGGATAATTTTGCGGTAAATG
+AATTAAGCAAGTCTTCATTTAATCAGGCGGCCATTATTGGTGAAGTCGGCACGGATAATA
+GTGCCAGAGTACGCCAGGAAGGATCAAAACTATTGTCCGTTGTTTCACAAGAAGGAGAAA
+ATAATCGGGCGAAAGTCGACCAGGCAGGGAATTATAACTTTGCGTATATTGAGCAAACGG
+GCAATGCCAACGATGCCAGTATATCGCAAAGCGCTTACGGTGATAGTGCGGCTATTATCC
+AGAAAGGTTCTGGAAATAAGGCCAATATTACCCAGTACGGTGCGCAGAAAACAGCAGTTG
+TAGTGCAGAAACAGTCGCATATGGCTATTCGCGTCACCCAAGGCTAATACCGTTACGACT
+TTTAAATCAATCCGATGGGGGTTTTACCATGAAACTTTTAAGAGTGGCAGCATTCGCAGC
+AATCGTAGTTTCTGGCAGTGCTCTGGCTGGCGTCGTTCCACGATGGGGCGGCGGCGGTAA
+TCATAACGGCGGCGGCAATAGTTCCGGGCCGGATTCCACGTGGAGCATTTATCAGTACGG
+TTCCGCTAACGCTGCGCTTGCTCTGCAAAGCGATGCCCGTAGATCTGAAACGACCATTAC
+CCAGAGCGGTTATGGTAACGGCGCCGATGTAGGCCAGGGTGGGGATAACAGTACTATTGA
+ACTGACTCAGAATGGTTTCAGAAACAATGCCACCATCGACCGGTGGAACGCTAAAAACTC
+CGATATTACTGTCGGTCAATACGGCGGTAATAACGCCGCGCGGGTTAATCAGACCGCATC
+TGATTCCAGCGTAATGGTGCGTCAGGTTGGTTTTGGCAACAGCGCCACGGCTAACCAGTA
+TTAATTTAGCGTCTGCGCTAATAAAAAAACAGGGCGTAAGCGCTGTTTTTTTTCGGGAGG
+AAATTATGCATACTTTATTGCTCCTTGCCGCACTTTCAAATGAGATTACGTTTACCACGA
+CTCAGCAAGGCGATATTTACACGGTGATCCCTCAGGTCACAGTAAACGAACCCTGCGTCT
+GTCTGGTGCAAATTCTCTCTGTGCGCGACGGCGTCGGGGGAGAAAGCCATACACAGCAAA
+AACAAACGCTATCTTTACCTGCTAATCAACCGATTGAGTTGGCTCGTCTTAGTGTAAATA
+TATCTTCAGAGGACTCGGTTAAAATTATTGTTACTGTTTCGGACGGACAATCACTGCATT
+TATCACAACAATGGCCGCCTTCTGCACAGTAGTTTTTGATGGTGGCGGAAATGGATTGGC
+TGACCTGGGTATTAAAGAGGCGATAAAAGCGTCTCATCGTCTCGGCATGTCGCTAAAAGG
+TAACGCCGAACCCTCGAGGATGACTAATCATTGAGGAGTTAACATGTCCGTAATCAAGAA
+AAATATCCCTGCCATAGGCCTGTGTATCTGCGCTTTTTTTATCCATTCTGCGGTAGGGCA
+ACAAACGGTACAGGGCGGCGTTATCCATTTTCGCGGCGCGATTGTTGAGCCACTGTGCGA
+TATTTCTACTCACGCCGAAAATATTGATTTAACCTGCCTACGCGAAGGTAAAAAGCAAAT
+GCACCGGATAGACCTTCGGCAGGCATCTGGATTACCGCAGGATATTCAGTCCATTGCGAC
+GGTACGGCTGCATTATCTCGATGCGCAAAAAAGCCTGGCGGTGATGAATATTGAGTACCG
+TTAACGGCGGTGTCATAGATATAAAAAGAGCGACTCTGTTGAAAGCCCTGCTGTACACTT
+TGCAGATAAGGTGAGACAAAAGGGGGGGGTTATGACATCACGTCTTCAGGTCATACAGGG
+TGATATCACTCAACTTAGCGTCGATGCGATTGTGAATGCCGCTAACGCATCATTAATGGG
+CGGCGGTGGCGTAGACGGCGCAATTCATCGCGCGGCGGGGCCGGCATTGCTGGACGCCTG
+TAAACTCATCCGTCAGCAACAGGGCGAATGTCAGACGGGACATGCGGTTATCACGCCTGC
+TGGCAAGCTTTCGGCAAAGGCGGTTATTCACACAGTGGGGCCCGTCTGGCGAGGCGGCGA
+ACACCAGGAAGCTGAGCTACTCGAAGAGGCATACCGGAATTGTTTGCTGCTTGCCGAGGC
+GAATCACTTTCGTTCCATCGCTTTTCCGGCAATCAGTACCGGCGTTTATGGCTATCCACG
+CGCCCAGGCCGCTGAAGTCGCCGTCAGGACGGTTTCAGATTTTATTACCCGTTACGCTCT
+GCCTGAACAGGTATACTTTGTCTGTTATGATGAAGAAACTGCCCGGCTTTACGCAAGATT
+ACTTACTCAGCAAGGCGACGACCCTGCCTGATAAAACACGCCTGGAGCGTGCCGTTGAAC
+CGCTATGCGCGCGCCATCCCGGAGAGTGCGGCATTCTTGCGCTGGATAACAGTCTGGACG
+CTTTTGCCGCCCGCTACCGCCTGACCGAAATGGCGGCGCGGACGCTGGATGTGCAGTATT
+ATATTTGGGAAGACGATATGTCCGGGCGGCTGCTCTTTTCGGTTCTGCTGTCGGCGGCGA
+AGCGCGGCGTTCATGTTCGTCTGCTGCTGGATGATAACAATACGCCTGGTCTGGATGATA
+CGTTGCGCTTGCTGGATAGCCATCCTAATATCGAAGTTCGTCTGTTTAATCCTTTCTCTT
+TTCGTACGCTACGCGCGCTGGGATATTTGACGGATTTTGCGCGGCTGAATCGGCGGATGC
+ACAATAAAAGTTACACTGCCGACGGCGTAGTGACGCTGGTCGGTGGGCGCAACATCGGCG
+ATGCCTATTTCGGCGCTGGCGAGGAGCCGCTATTTTCCGATCTGGACGTGATGGCCATTG
+GCCCGGTGGTCAATGATGTCGCCAATGATTTTGAACGTTACTGGCGCTGTAGTTCAGTGT
+CGACATTGCAGCAAGTATTATCCCTTTCTGAGCAGGAACTGACGCAGCGTATCGAACTTC
+CCGAATCCTGGTATAACGATGAGATCACCCGCCGTTATCTGCATAAGCTGGAAACCAGCC
+AGTTTATGGCGGATCTCGATCGCGGAACGTTGCCGCTGATTTGGGCAAAAACACGCTTGC
+TTAGCGATGACCCTTCTAAAGGCGAGGGGAAGGCGCAGCGCCATTCGCTTCTTCCGCAGC
+GATTATTTGACGTGATGGGGTCGCCGACGGAGCGTATCGACATTATTTCCGCTTACTTTG
+TCCCTACGCGCGCAGGCGTGGCGCAGTTGCTTAATCTGGTCAGGAAAGGTGTGAAGATCG
+CCATCTTAACTAACTCTCTGGCGGCCAACGATGTGGCGGTCGTTCACGCAGGGTACGCGC
+GCTGGCGCAAGAAATTACTGCGCTATGGCGTGGAGCTCTACGAACTGAAACCGACCCGCG
+AACATGAAACCGCCGTACATGATCGCGGACTCACCGGGAACTCAGGTTCCAGCTTACATG
+CTAAAACGTTCAGTATTGATGGTAGTAAGGTGTTTATCGGGTCGCTTAATTTTGATCCCC
+GTTCAACGCTTTTAAATACCGAAATGGGCTTTGTCATTGAAAGTGAAACGCTGGCGACGC
+TTATTCATAAGCGTTTTACGCAGAGCCAACGCGATGCGGCCTGGCAACTGCGGCTGGATC
+GCTGGGGACGAATTAACTGGATCGATCGTCAGCAAGAAGAGGAAAAGGTGTTAAAGAAAG
+AACCCGCTACGCGTTTCTGGCAGCGAGTTCTGGTACGGTTGGCGGCAATTTTACCTGTGG
+AATGGTTGCTGTGAACCCGCGCGCGGAAAACTACCCGATCGCGGCGCGGCTTTCTTGTTT
+TACCGGCGGTTTACCTGAAAAGAGAAATTTCAGGAGCGGGATGCGTAAATGAATTTCATA
+CAGAATTAACGCAATACCCATAACAAATATCAGCCCGCACAAGAACCCGATCAGGTTGGA
+GGAGATATGCGGTGTAATATACGCGCCAAAGAAAAGCGTTAAGGGATGATGCACCAGATA
+AATAAACAGCGAAGCATTCACGAAATAGGTGACACGCGCGGACTGAAAGTTTAACAAGCG
+ATGCCCCAGTGAAAATACCACGTTCACCATCCATAGCCCCATTACCATCGTAATCACGGA
+TTCGGTTTCGTACATCCAGGCGTCGCCGCTCCCATAACGTTGATTCAGCAGATACGCGAT
+AAAAGCAACGGCAGCGCCTAAAGTGCATCCGCGTGAGGGCGTGGTGAAGCGCGCTTTCAG
+ATCGGGGTGAATGAAGGCCAACGCGCCGAGAATAAAAAACGGCACATAAAATAGCGTTTG
+CATCACAATAAAATTGAACATGCCGTCACTGAGGATTGCCGGATATACGATGAATATAAT
+GCGCCTGATAGCAGCGTACGCCACCCCCAGCAGGAAAAAAATAAGCGAAAGTTTGGCCAG
+CGAAATAGCGGCGGGACGAGGCTTGCTTGTTTCCTGCCTTTTTTGGAACCAGGTAAAAAT
+CCCGATGCTGACGGTGGTTAATATCACCAGCACCAGTAAAAACCACAGATGTGAAATGAG
+TTCCCACGCTAACGTATTATATTTTTCATAGGCAGAGAGTGTAGGCCAGTTCTCTGTTTT
+CTCTTTGACATATTGCAACAGGATAAATTGCGGCAAGGTAAGCAAAGGGATTGCGGTAAG
+CATGGGAATACCCACACGTTCTACCCGTACTTTCCACCAGTGTTTTAATGGATAACGTAA
+AAATAACATGTACGAAAAATAACCAGAAATAACAAAAAACACCTGCATACGAAAAGCGTG
+GATAAAATCGTTAAACAGGGTTAGCCACCACGATGGCGCGGCGCTATTGACATGCCAACT
+GTGAGTGGAATAGATCAACGAGATATGAAAGGGAATCCCTAACAACATCAGCCATGCGCG
+GATAGAGTCAAGAAAATATTCACGCGGCGCGGGTACAGAGCTCATATAAGGTCACGTATT
+CTCAGATTTTTCACCTTATCCATAAGGCGAATTATAGTTACATTCGGTAGCAACCCTACA
+CCAACTCCGACAACCTGTCTCCAGGATAAGCACGCAAAGTGAAAACAGGCGCGGGAGGTG
+CTTAATCCATGAGCCAGCGCGCTGAACAAAGCCTGGATTCAGTTGTCGTAATGCCTGATT
+ATCCATTAAAATGGATCGGATCGATATAAGCACACAAAGGGGGAAGTGCTTACTTATTAT
+GAAACATAAACGACAAATGATGAAAATGCGTTGGTTGGGCGCAGCTATTATGTTAACGCT
+CTACGCATCATCGAGCTGGGCGTTCAGTATTGATGACGTGGCAAAACAAGCTCAATCTTT
+AGCCGGGAAAGGCTATGAGGCGCCTAAAAGCAACTTGCCCTCCGTTTTCCGCGACATGAA
+ATATGCGGATTATCAGCAGATCCAGTTTAACAGCGATAAAGCCTACTGGAACAACTTAAA
+GACCCCTTTTAAGCTCGAATTTTACCATCAGGGGATGTACTTCGATACGCCGGTCAAGAT
+TAACGAAGTGACGGCGACGACGGTCAAAAGAATCAAATACAGCCCGGATTACTTCAATTT
+TGGCAATGTTCAGCACGATAAAGACACGGTAAAAGATTTAGGCTTCGCCGGGTTCAAAGT
+CCTGTACCCCATTAACAGTAAAGATAAGAACGACGAAATCGTCAGTATGCTTGGCGCCAG
+CTATTTCCGCGTTATCGGCGCAGGCCAGGTGTATGGCTTATCTGCGCGCGGCCTGGCGAT
+TGATACCGCCTTACCATCTGGTGAAGAGTTTCCCCGCTTTCGCGAGTTCTGGATTGAGCG
+TCCAAAACCCACCGATAAGCGTTTGACCGTCTATGCATTACTGGATTCTCCGCGCGCGAC
+CGGCGCTTACCGTTTTGTGATCATTCCTGGCCGCGATACCGTGGTGGACGTGCAGTCAAA
+AGTCTATCTGCGCGATAAGGTGGGCAAGCTGGGCGTTGCGCCATTAACCAGTATGTTCCT
+GTTTGGGCCAAACCAGCCGTCGCCGACGACCAACTATCGTCCGGAATTGCATGACTCGAA
+CGGCTTATCCATTCATGCGGGTAATGGCGAGTGGATTTGGCGTCCGCTGAACAATCCAAA
+ACACCTCGCTGTGAGCAGCTATGCGATGGAAAACCCTCAGGGATTCGGCCTGTTGCAGCG
+TGGTCGCGAGTTCTCGCGCTTTGAAGATTTAGACGATCGCTATGACCTGCGTCCAAGCGC
+CTGGATTACCCCGAAAGGCGACTGGGGCAAAGGTAAGGTTGAACTGGTTGAAATTCCGAC
+CAATGATGAAACCAACGATAACATCGTCGCTTACTGGACTCCGGATCAACTGCCGGAACC
+GGGTAAAGAGATGAACTTCAAGTACACTCTGACCTTCAGCCGCGATGAAGATAAACTTCA
+TGCGCCGGATAATGCCTGGGTGCTGCAAACACGCCGCTCAACGGGCGACGTTAAACAGTC
+GAATCTGATTCGCCAGCCCGACGGCACTATTGCCTTTGTGGTGGATTTCGTTGGCGCCGA
+CATGAAAAAACTGCCGCCGGATACGCCCGTCGCTGCACAAACCAGCATTGGCGATAACGG
+TGAAATCGTTGACAGTAATGTACGCTATAACCCAGTCACTAAAGGCTGGCGTTTAATGCT
+GCGCGTGAAAGTCAAAGACGCGAAGAAAACCACGGAAATGCGTGCCGCATTGGTGAATGC
+CGATCAGACGCTAAGTGAAACCTGGAGCTACCAGTTACCTGCCAATGAATAAAACAACTG
+AGTATATTGACGCACTGCTGCTTTCTGAACGTGAGAAAGCGGCATTGCCGAAAACTGACA
+TCCGCGCCGTGCATCAGGCGCTGGATGCCGAGCATCGGACTTACTCGCGAGAAGACGATT
+CACCGCAGGGTTCCGTAAAAGCCCGCCTTGAACACGCCTGGCCGGATTCATTGGCGAAGG
+GGCAGTTAATTAAAGATGATGAAGGGCGCGATCAGTTGCAGGCTATGCCAAAAGCGACGC
+GCTCTTCGATGTTTCCTGATCCCTGGCGAACCAACCCGGTTGGCCGTTTCTGGGATCGCC
+TGCGTGGGCGGGATGTTACGCCGCGCTATGTTTCTCGTCTGACAAAAGAAGAGCAGGCGA
+GTGAGCAAAAATGGCGTACCGTCGGCACTATACGCCGCTATATTTTGTTAATTTTGACTC
+TGGCGCAAACCGTCGTTGCGACCTGGTATATGAAGACCATTCTGCCCTATCAGGGATGGG
+CGCTCATCAATCCTATTGATATGGTGGGGCAGGATATTTGGGTCTCCTTTATGCAGCTCC
+TGCCCTACATGCTGCATACCGGTATCCTGATTTTGTTTGCCGTGCTGTTCTGCTGGGTGT
+CTGCCGGATTCTGGACTGCGCTGATGGGCTTCCTGCAACTGCTTATCGGGCGCGATAAGT
+ACAGTATCTCCGCGTCTACGGTTGGCGATGAGCCCCTCAATCCGGAACACCAGACGGCGC
+TGATCATGCCTATCTGTAATGAAGACGTTAGCCGCGTTTTCGCCGGTCTGCGCGCGACCT
+GGGAGTCCGTTAAAGCTACAGGCAACGCCGCGCATTTTGACGTCTATATCCTTAGCGATA
+GTTATAACCCGGATATTTGCGTGGCGGAGCAAAAGGCGTGGATGGAGCTCATCGCGGAAG
+TGCAGGGCGAAGGCCATATTTTTTACCGTCGCCGCCGCCGCCGTATGAAACGCAAAAGCG
+GCAATATTGACGATTTTTGCCGCCGCTGGGGCAATCAGTACAGCTATATGGTGGTGCTGG
+ACGCGGACTCAGTGATTAGCGGCGAGTGTCTGAGCGGGCTGGTGCGCCTGATGGAAGCGA
+ACCCTAACGCCGGGATTATCCAGTCTTCGCCGAAAGCGTCGGGGATGGATACTCTGTATG
+CCCGCTGCCAACAGTTTGCGACCCGTGTTTATGGACCGCTGTTTACCGCCGGGCTGCACT
+TCTGGCAGTTGGGGGATTCGCACTACTGGGGGCACAATGCCATTATCCGCGTGAAGCCGT
+TTATCGAGCACTGCGCTCTGGCGCCGCTGCCGGGAGAAGGTTCGTTCGCCGGATCGATTC
+TTTCCCACGACTTTGTTGAGGCGGCGCTAATGCGTCGGGCAGGGTGGGGCGTCTGGATTG
+CCTACGATCTCCCCGGTTCCTATGAAGAGCTGCCGCCAAACCTGCTGGATGAGCTTAAAC
+GCGACCGCCGCTGGTGTCACGGCAACCTGATGAACTTTCGTCTGTTCCTGGTGAAAGGAA
+TGCACCCGGTGCATCGTGCCGTGTTCCTGACCGGGGTAATGTCATACCTGTCCGCGCCGT
+TATGGTTTATGTTCCTTGCGCTTTCTACCGCGCTGCAGGTCGTTCATGCGTTAACAGAGC
+CGCAATATTTCCTTCATCCGCGCCAGCTTTTTCCGGTCTGGCCGCAGTGGCGTCCGGAAC
+TGGCAATCGCGCTGTTTGCGTCAACGATGGTGCTGCTGTTCCTGCCGAAGCTGCTCAGTA
+TTATGCTGATCTGGTGTAAAGGCACCAAAGAGTATGGCGGTTTCTGGCGCGTTACGCTGT
+CGCTATTGCTGGAAGTTCTGTTCTCCGTGTTGCTGGCGCCGGTGCGTATGCTGTTTCATA
+CCGTGTTTGTGGTCAGTGCGTTCCTCGGCTGGGAAGTGGTCTGGAACTCACCGCAACGCG
+ACGATGATTCTACGCCTTGGGGAGAAGCCTTTATGCGTCACGGCTCTCAACTGCTGCTGG
+GGCTGGTCTGGGCGGTTGGTATGGCGTGGCTGGATTTACGCTTTCTGTTCTGGCTGGCGC
+CGATTGTCTTTTCGCTTATTCTGTCGCCATTTGTTTCGGTGATCTCCAGTCGTTCAACGG
+TAGGATTACGCACCAATCGCTGGAAGCTGTTCCTGATCCCGGAAGAGTATTCGCCGCCTC
+AGGTGTTGGTCGATACTGATAAATATCTGGAGATGAATCGCCGCCGTATTCTGGACGATG
+GCTTTATGCATGCGGTTTTTAACCCGTCGCTTAATGCGCTGGCGACCGCGATGGCCACCG
+CGCGTCACCGCGCCAGTAAGGTGCTGGAAATAGCCCGCGATCGTCATGTGGAGCAGGCGC
+TAAACGAAACGCCGGATAAACTGAACCGCGATCGGCGTCTGGTTTTGCTCAGCGATCCGG
+TGACGATGGCGCGTTTTCACTATCGGGTCTGGAATGCGCCAGAGAGATACTCTTCCTGGG
+TAAACCATTATCAGTCTCTCGTCCTGAATCCGCAGGCGTTGCAGGGACGAACATCGTCAG
+CGGGATAAGGTCTTCATGTCTGGAGTGAGGTGAAAAATACCGGCGTGATGCCGGTATTTT
+TATAGTGAAATGAGGTTTCAGGTGCGTATATTCGCGGTGAGCATAATGGTGATTACCCTG
+AGCGGCTGCGGCAGTATTATCAGCAGAACGATCCCCGGACAAGGACACGGCAACCAGTAT
+TACCCTGGCGTGCAGTTGGATATGCGTGATTCCGCATGGCGCTATATCACTATCCTCGAT
+CTGCCCTTCTCACTGATCTTCGATACACTGCTACTGCCGCTCGATATTCACCACGGGCCT
+TATGAGTAATTAACGCTCATCCCATTCGTCTGCCGCAGTACGGCCTTCCTCGGTATCAAG
+CGGGGGTTCAAGCTGGTATTCCCCTTCATCCCATTCATGCAAAGTATTCTCTTCCTGCCA
+TTCCTGGCGGATCTCTTTCTCATCATAATCGCCGTCAAACACGCTCTGTGCGGCTTCACC
+ACTCAGCATCGGCAGATATTCGCCATCTTCACCTTCATCGGCGAAAAATTCGACCTGCCA
+CATGATGTCCCCATCCTGCAGTACATATTTCTGAACGTTGAACTGCTGCACATTCGCTTC
+GTCTTGTTCGAGGCCTTGATGGTCAGCCAGAAATTCTTCCCGGGCTGCATCGATAGCTTC
+TTCCAGCGTGGCATACTTGGTCATCAGTGTCTCCCTTTGATTTGACGAGGTATTTAGGGA
+AAGAATAGCTGATTCTTTGATATTGCAAGTATGAAAGCGCAAAAATCATTCTATTGCCAG
+TCTGCGCCGTCGTAAGTTGTTCCATGAATAGATAGCATTGAACAACACCACGCCTGCCGT
+GACGCAGAATACGGCGTGGAAGCCATAGCTCGCGGAAATTGCGGCACCCATGAGAGGGCC
+GGTGACGTTGCCGATATCGCGGAAAGATTGGTTGTAACTGAATATGCGCCCGGCTATCTG
+GTTGGTAGAGTTGTAATCCAGCAGAGTTTGAACGGCTGGCAGCAGCGCGCCATCCGCCGC
+GCCAAGCAGAAACCGCTATAGCGCGAGCTGCCACGGCGTTTGCACAAAAGACATTGGAAT
+CAGCAGCAGTACGGAATTAATCAGCGCGACGATAAGGATCTTTTCCGGGCCAATTCTGTC
+GCCGAGCTTGCCGAGCTGGGGGGCGCTAAGTAATGCCGCCACGCCGGGAACGGACGCTAT
+CATCCCGCTAATGAACTCAATATTACTGACATTTCCCGCGAGTTCGCGCACATAGAGCGT
+CAGGATGGGCGCAATATACCCCGTCGCCACCTGAATAATCAGCGTGGTGACAAACAGGCT
+TAACACCAGGCGGGGATTTTTTAACGAGGCGACCACTTCCCGAACGTGAAGCATCTCTTT
+TTTGCTCACCGGCAGGTAATTCTCGCGAATAAAAAAGAAGGTGAGCAGAAAACAGATAAA
+CAAAACGCTGGCGGTATTAAAAAAGACCGGGCGAAGGCCGTAATGGTCGGCGAGCAGACC
+GCCCGCAAGTGGGCCATGCAGAGCGCCGCTGACGCCGCCAGTAGAGAGCGTCCCTAACGC
+CCAGCCGCTTTTGTGGTGCGGCACCTGAGTGGCGATGAGCGCATTGGCGTTGGGAATAAA
+TCCGCCCAGCAGGCCTTATAACGCGCGGAGGATCAGAAATTGCCAGATATTTTGCGCCAT
+GCCCATTAACAGCATCTCAATGGCCATGCCGAGAGCGGAACGCAACAGTATGATCTTACG
+CCCTTTACGATCCGCCTGACCGCCCCAAAAAGGGGAAGCGATAGCTGAAAAGAGGAACGT
+AATACTAAAGACCAGCTCGGACCACATGTTGAGCGCGCTATGGCCTGTTACGCCGAGTTG
+CTCAACGTAGAGAGGGTGAAAAGGCATGACCAGACTGAATGCCGCGCCGGTTAAAAAACA
+GCCCAGCCAGGTAACGTTTAGATTGCGTTTCCAGTTTATGGGGACATCAGAGGGTGACAT
+AGTGTTCCACAGTATGTTGCGCGTTTTGCGCTATCATCAATTTAATTATGAGCGTACTAA
+TTATAATTATGCGCCGTCCTTACCAGCCTCGCAATGTGGGGAGCTTTTAAAGCTAAAAGA
+GGGGAAAAATTGCAGCTTGACGGCTGCAATCCTGTCAATAGCGCGACGGTACGCCTTCAG
+GGCGAGTTTTAAAGCGTCGATGCAGCCACATATACTGCTCTGGCGCCATCATAATGCACT
+GCTCAACAATCTTATTTATCCATGCGGCAGTCGCTTCTGCGCTCTCCAGCGGAGGCGAAT
+ATTCCGCAGGAAGGATTATCAGTTCGTAGCCTTTCCCGTCGGGTTTACGGCGAGGCACGG
+AGGGGATAATACAGGCTTTAGACATGCGCGCGAGCATCCAGGTACCGGAGGTCGTAGCGG
+CCTGGTCGACGGCGAATAACGGTACAAAGACGCTGGCGCGCGGGCCATAATCGTGATCCG
+GCGCATACCAGATCAATTCGCCGCTTTTCAATGCCTTAACCATACCTTTCAGATCTTTGC
+GATCCAACATCGATTTTTTGGAGCGTAAGCGCCCCCAGGTCTGTAACCAGTCGAGCAACG
+GATTATCATTCGGGCGTTAAACGCCGATACCCGGGTTATGCATACCAAACATGCGGGCGC
+CAAACTCAAGGGTAAGTAAATGTATTCCTACCAGAATGAACCCCAGCCCCTGCGCCTTAA
+CTTCACGGATATGCTCTAGACCGCTCGCTTCCATCCAGCGGTTCACTCGCCGATCGGGCC
+AGAACCAGGCCATGCCTGTTTCCATCACGCCCATACCGACGGATTCAAAGTTTTTGACCA
+CCATGGTGTGGCGTTCTTGCGCGCTCATTTCCGGAAAGCATAATTCAAGGTTGCGATAGG
+CGATTTTCGCGCGGCGTTTCATTACGCGTCGCGCCAGGTGGCCCAATGCGCAACCCAATT
+TATAGATGACCGGGTATGGGAGTTGCACGACCAACCAAAGCGCGCCTATACCCAACCAGG
+TTAACCAATAGCGCGGTTGCAGTAAGGCCACGGAGAACTTAGGCAACTTCGTCATTTCTA
+TCCTGTCTTTCAACGATCAATTCTCCGTATTCTCGCATCTTTTTGCGTTGAGCAAAAATA
+TGTAGCAGGAGAGTGGTGATTAAATCGACAATTGTTGTTAATTATTTAGCGTAAAGCAGG
+AAATGTAGCGCAAAATTTGTGGATGTAAATTGGCGAGACTTGCCTTATCATGCCTGCCCA
+CTTTATTTTTTGCTGATTGCAGGATACGTACACCATGCCAGTGTTACACAACCGCATCTC
+TAATGACGAGCTGAAATCCAAAATGCTGGCGGAAAGCGAGCCGCGTACGACAATTTCTTT
+TTATAAATATTTCACTTTCGCCTCGCCGCAACAGACGCGGGACGCGTTGTATCAGGTGTT
+TACGGCGTTGGACGTTTTTGGTCGCGTTTACCTGGCGCATGAGGGCATCAATGCGCAAAT
+CAGCGTGCCGCAAAGCTAGGTTGAGACCTTTCGTCAACAGCTTTATACGTTCGACCCCGC
+GCTGGACGGGGTGCGTTTAAATATCGCGCTGGAGGATGACGGAAAGTCATTTTGGGTGCT
+GCGTATGAAAGTTCGCGACCGTATCGTCGCTGACGGTATTGACGATCCGAGTTTTGACGC
+CAGTAATGTCGGCGATTATCTGAAGGCGGCAGATGTGAATGCGATGCTGGACGATCCTGA
+CGCGGTCTTTATTGATATGCGCAACCACTATGAGTATGAAGTCGGCCATTTCGAAAATGC
+TCTGGAAATCCCGGCGGATACGTTTCGTGAACAGTTGCCAAAAGCGGTTGAAATGCTGCG
+GGAACATGCAGATAAAAAGATAGTGATGTACTGTACCGGCGGTATTCGTTGTGAGAAAGC
+CAGCGCCTGGATGAAACACAACGGTTTCAATAAAGTCTGGCATATTGAGGGTGGCATCAT
+TGAGTACGCCCGTCGCGCGCGCGAGCAGGGGCTTCCCGTTCGCTTTATCGGCAAAAACTT
+TGTATTTGATGAGCGAATGGGCGAGCGCATCTCGGATGAGGTTATCGCGCATTGCCATCA
+GTGCGGCGTGTCCTGCGATAGCCATACCAACTGCAAAAACGACGGTTGCCATCTGCTGTT
+TATCCAGTGTCCGCAGTGCGCCAGTAAATTTAACGGCTGCTGTAGTGAACAATGCTGTGA
+AGAGTTGGCCTTGCCGGAGGAAGAACAGCGCCGACGTCGCGCGGGTCGTGAGAACGGCAA
+CAAAATTTTTAATAAATCGCGGGGTCGGCTTAATAGCAAACTGAGCATTCCCGATCCGGC
+TGAGTAATATTTTGCCGGATAGCGGCGTAAAGGCTGCTATCCGGCATTTCGCCAGGCGTT
+ACTTCTGCTGAACGCCTTCTACTGAGATGATAAGCTCCACCTCTTGTGAGGCTGGGCCGA
+GATCGGTAGTTATATTGAAATCTTTCAGCTTAATTTTTCCTTCGGCCTCAAAGCCCGCGC
+GCTTACCGCCCCACGGATCGTCGCCCTGGCCCATCAGCTTCGCTTCCAGCGTCACCGGTT
+TAGTCACGCCATTGAGCGTCAGATTGCCGGTAATATCCAGTTCATCGCCCTCTTTTTTCA
+CGCTGGTAGAGGTGAAGGTTGCCTGCGGGAATTTCGCAACATTAAGAAACTCCGCGCTAC
+GCAGGTGTTTGTCACGTTCGGCATGGTTAGTGTCGACGCTATTGGTGTTAATGGTCACAT
+TCACTTTGTCTGCTGACGGATTTTTTTCGTCAAAAGTGAACGTGCCGTCGAAATCTTTAA
+AGGTGCCGTATAGCCAGCTGTAGCCCAGATGCTGGATGCGGAAATTGACGAACGCATGTT
+GGCCTTCTTTATCAATTTTATACTCCGCCGCCACGGCGGAACCGGTCGTGAATAACAAGG
+ATGCGAGGGTGAATCCCAGCAGGTTTTTTTTCATTTTTGAGCTCCATAGTCAGATGACGA
+CATTCCTGTCATACGTTTCAGTGTGTCGTCTTTATCGATGAAATGGTGTTTTAGCGCCAT
+AACCCCATGCGAGAGCGAGATAATGACCAGCGACCAGGCAAACCACAGATGCAGTGTTCC
+GGCGATGTCAGCCTGCGCGCCCGCGTCCGTAAGCGTGGCCGGAATCTCAAACCAGCCAAA
+GACGCTAATCGGTTTACCGTCGGCGGTGGAAATCAGGTAGCCGCTAATGATTATCGCAAA
+GAGCAGGAGATACAGAAGGATATGACCCGCGGCGGCGCCAATGCGCGTTAAACGGGAATA
+GCTGGTCAACGCAACGGGCGGCGGAGAATAAAGCCGCCAGATAATACGCACGATCAGCGC
+CATCATCAGTAACATGCCAATACTTTTATGTATTTCCGGCGCCTAGTGATACCAGCCGTC
+GTAATAACTGAGCGTGACCATCCATAAACCCAACGCAAACATGCCATAGACCACTAGGGC
+GGTCAGCCAGTGGAGGGCGGCGGAAACTACGCCATAACGTTGTGGAGTATTTTTAAATTG
+CATAAACACACCAATGAATATTTCACGAGAGAATGAAAATGGCGTGGAAAAGCGCCGAAT
+GCAACTTATAAATAAGAATTTGAATGATATTTATTTTTATTTCAATAATTTTGATGTTGT
+TTGCGATTCAGCTTCAGAAGTTTCGAGATATTTCACTCCTGTAACCGCACAACGGCAGGA
+GTTGGCATTATTGCCGTGCTTCAACATTATGAAATAAAAAGTGAGGAACTTTCAGGAAGT
+GTTAGTTAACGTCAATGAAAAGCAATCAGAAGAAAAGGAGATAAACAATATCCATCACCG
+CCAGCAGCGACCAAAGAATAACGTAAAGCATGAAATGTTCGCGAATATTATTCATCAGAA
+AATGAAAGAGACGACGCATAGCTTACCTTAATAAACAGCCCCTTTACGGGGCCGACAAAT
+TATTGGCTAAAACGGGAAAGCCGGAACGGCGTCAGATCAAAGGAGGGCGTTTTTCCCAAC
+GCAAAATCCGCAGCGATTTCTCCTAACACCGGGGCGAATTTAAAACCATGTCCGCTGAGT
+CCAGTGATGACAAGCGTATTCTCATGGCCAGGCAGCGTATCGATAATAAAATCCTCGTCC
+GGCGAATTATCATAGGTACATGCCGCCCCATGTAAACAACCGCCGATACCCGGCAGTACG
+TTACGCAGGAAAGGAAATGCTTCCGCGCCATCGCTGGCAACGGCGGCAAAGGGCTTGCGC
+TCTTCCGGTGCCTGTATTCGCTGCCCGCCATTGTGTTTGCCGATTTTTAACTCGTCGTTC
+TCCGCCGGGAAACCGTAATAGTGATCGCCGTTGGGCATTTCGCCGGTAAAGGCCGGAAAG
+CGGTTTTTAGTGCTGTAACGTCCATCCGCCTTAAACCAGGCAAAAACTTTACGTACGGGC
+TGAACGGGCAGCTCCGGTACCAGCGTTTTGACCCAGGTGCCCGCGCTAATCAGCGCTTTG
+CTGGCGTGGTAGCAGCCTTCACTCGTCTCTATCGTCACACCGTTATCATCATGGTGAATA
+TGGCTTACCGGGCTGTTGAATAGCTGTGCGCAGCCTGCCTCTCGGGCCAGACGAAGCCAT
+GTGGTAATGGCTAATTCGCTGCGCAGGAAACCGGAGTCAGCTTCAAACAGCCCGATATAA
+TTATCGGGCACGCGAATTTCCGGCCAGCGCGTCATGAGGGCCGTCGCGTCCAGGCGCTCG
+ACGTTCAATTGCCACTGTTGCGCGCTTCGTGCGACGTTGGCTAAGAAAGCGGAATCGGCC
+GGGCCGAGGTTGACGACGCCGGAGCGGACAAAAATAGGCTCTTCATTGTGTGTGGAGAGC
+TCATCCCAAAGCGTCTGGGCGCGAAGCACCAGCGGGACATATTTTTCGCCTTCACCATAA
+GCGTGGCGGATAAGACGGGTATCGCCGTGGTGGCTGCCCTGTTGATAAGGCGGCATATGC
+GCATCGGTCATCAGGACCTTTAGCCCGGCGCGGGTGGCGTAATAACCAGCGGCGGCGCCA
+ACCGAACCGCTGCCGATAATAATAAGGTCGTATTTCATCAGCTTCTCTCTGCTATCGCGA
+TGATTTCAAGGTAAATAACTGCGCTGAGATATACAAGCCAGAAATAAGTGAGGCACCTTA
+CGGTGCCTGAGAGAGGGGGAGCGCGTCACGCTAATGGTGACGATACTCGTTTTCCTGGTA
+ATCGCCTGATTCTATTTTGGCGATGCCGGCTTCTAATATTGAAATAAATTGCCTGGCTAC
+ATCTGTCGTTAACCAGAGCGTTTGACCAACTTCAGTCCCTTCCGGTTCCGGACGATTTGG
+GGTCTGGTAGTGTAAACGCAGCATCAGCGCATCATAGCTATCGACGGTGCTGATGTCCCA
+TCCTACAAGCGGATGGGTCTGAATGACTTCATTATTCTTTTCCATCATGCCCCCCTGGTA
+CGTGTTATAAGACAACGGTTCTCGAGGTTCAATGCGTGTTTTTCTTCTGAAGCAACTTCA
+GTATACCAATTAATAAGGCTATTCACTGCGTTTTTAAAGAGACCGGAGGATAAATTTCTC
+TTTTTAAGAATTATATGAACAATAAAGCGGCAGTTCATTCATATTTTTTTAGGATGTTGT
+GCAATTATTTTGACGGTCAGGCGAAATATTCATCAGTTGCGCAAATAAAAAAGCCGGGGC
+GACCCGGCAAACATACATCACTGCATATCATTTTTTATTCATTGATGAACCAGTCATCAG
+CGCTCTCCCAGGTCTCCTGGAGAATCTCGCTAATGCGTTCTTTATCCTCTTTTGACGCGC
+CAATGACGGACAAGTTGTTGGCGGTAGCGTAACGCACGGTGACGTTACCCAAATTCTCAG
+GAAAATGATGGCTAATACGGCGGGNNNNNNNNNNNNNNNNNNNNNNNNNNCCCGCCAGCG
+CACCAATCGCACCGGCAGGCAGAGGTGACGTTTTGGCTATAGTGACTTCAATACGCATAA
+TGGCCCCCTGTTGAATATACTGGATATATATACAGTTAAATCCAATATATAGCAACAGGT
+AAGCGCATTTTTTATTTTTTTACTGACCAGCGTACTGTTTCACCCGCTAAAAAAGGCACC
+AGCGAATCATCAGCCAGCGCGATATTTTNNGGTATCTGTTGTTCATCGCGAACCAGTTCC
+ACCCACCCCGTATTCACCGGCAGGCCATNNAATTGCGGGCCATTCAGTGAACAGAACGCT
+TCAAAGTGCGCCAGCGCGTTCATTTCCTNNAACACGGCGGCATAACTGCCAAGAGCGGAG
+GGGGCGTTGAAACAACCGGCGCAGCCGCNNCGGGTCTCTTTACGATGACGTGAATGCGGC
+GCTGAATCCGTCCCCAGGAAGGCGCGCGNNAAACCACTGGCGACCAGGTCGCGTAACGCC
+TGCTGGTGAATATTGCGTTTCAGAATCGNNAGACAGTACAGGTGAGGACGAATGCCGCCA
+ACCAGCATATCATTACGGTTAAACATTANNTGTTGAGGCGTAATGGTCGCCGCCAGGTTG
+TAGCTGCCGTCACGTACATACTGCGCGGNNTCTTTGGTTGTGATGTGTTCAAAGACCACT
+TTAAGCGCGGTCAGACGCTGGCGTAGCGNNTCCATTACGGTGTCGATAAAACGCGCTTCG
+CGATCGAAGATATCAACATCCGCATGGGNNACCTCACCGTGGACCAGCAATGGCATTCCG
+AGTTTTTCCATCCGCTCCAGTACCGGCANNATAGCGTCGACTGACGTTACGCCATGACTG
+GAGTTAGTGGTGGCATTGGCCGGGTAAANNTTGGCCGCAGTAAACACGCCTTCATGGAAA
+CCACGCTCCAGTTCATCGGCATCGAGCGNNTCCGTTAAATAGCAGGTCATTAACGGCGTG
+AAATCATGCCCGGCGGGCACCGCATCGANNATACGCTGGCGGTAGGCGATCGCTGCATCA
+ACGGTCGTAATGGGGGACGCCAGGTTCGNNATCACGATAGCGCGACCATAAATTTCGCTG
+GTATAGGGTACGACCGTTTTTAACATGTNNCCATCGCGAAGGTGAACGTGCCAGTCGTCC
+GGGCGGCGGATCTTTAAAACCTGGGATGNNGCAGTCATTAATAAGCTCCGGCTGAGGAAT
+AGTCTTTTTGCCGGAAACAAAGGATAAGNNGAAACGTTTTCGTTTGCACGTAAAAAAAGG
+GCGCGAGCGCGCCCTCCGAAATCAATTGNNGAAAGGAATAACGATTTCACCAGGTTTAAC
+TTCAATGCCTTTCGCGAGTTTCTTCGCTNNCGCTTCGCCTTTACTACTGTCCTCACGCAA
+CACGTAAGCGGGCCGCTGGTTAAAGTAGNNACGTAAAGACTGATTTAAATAGGGCAGGAG
+CGTTTGTAGCACTGATTGCATTTTCTCCNNCGTCACGGTGGCGTCTACTACTTCCATCTC
+CTGAAGATAGATGGCGCCTTTTTCTTTANNAAAGACCGGCAGGGCTTTTAGCTTGAGTTT
+CATCGTCGCTTTTTGACTGCCAAACAGGNNATTCATATCCAGCCTGGCATCGCCAGTAAG
+GGTGACTTTATTAGGCTCTTCCCGACCANNCTGGCTGGCAAGGTTAGTCAATACGATATG
+CGCGTCGGCAATGCCAGGCAGACCAATANNTTTTGAGAAATTATTCCGTTTTTCAAGCGC
+TTGATTGATTTCTTGTTCGCTAATGGTGNNTTGCGTAAGTTGATTACAACCCACTAACAG
+GCCGCTAACTACCAGCGCAGCGGCAAAANNAACTTTTTCATGGCGTTCCTTAGCATGTTG
+CCTGTGCCCTAATCTTGACACAAAGCAGNNTGTCGCGCCAGCGGACATGGCGCCACTAAA
+AAAAGCTGAAAAAGGCGGCAAGAAAGGGNNGCCGCCTGGCGGGCGTTAGATAGCCATTGA
+GGAGAGTAAATTAATTTGCGTCTGCTTANNCATATTATCGCGATAGTCCGCGACTTTTGT
+CGGCCAGTGAATACCGGCGACCAGCGTCNNATTACGCAGAAGCGGAAACAGATGAATATC
+ATCTTCCGATAATTCGCCGTTAACGGCGNNAGGCTGTACGATGAGTTTATCCAGCAAACG
+TAAATCATCGCCGATCTTTTTAATCAGTNNGGCAGAGTGCGCAAGATGGTTGTCAAAACT
+GCCAGATGAGGCCTCTTTTTTGCGGATANNATACTGGCGCGCCGCAGGGGTAGAAAATTC
+ATCGAAAGCGGATTTTGCAAATCGCGGCNNCAGTAGCTGATTAACGTAACCGTTAACTTT
+GCGCAACCACTCTTCAATGGCTGGATTANNTTTCCCGGTTAACAGCGGTTTGCCGTCGAG
+GTTGTCGACATAATGTACAATATCCATANNTTCAGGAAGGTAGCGACTATCATCTTTTTG
+CAGGATGGGCACCATCTTTTGACCAATCNNCCGGGTGGGCGTCGCCTCGTCGTCATTTTG
+TAACACGTTAAGTTCAACGGGGATGTTCNNCAGGCCGAAAATCATGCGGGCTTTAACGCA
+GAAAGGGCAATGATCGTAAATATAAAGCNNCACGTTTCTCCTCCATTTGACTGTCGGTTC
+CTGACCAGTATGGAGGAGATAGCGACAGNNATCAAATCAGGCGCCGGGTTCCAGCATCCG
+GCGCGGCGTGCGCTTATGACTAAATTGCNNGCCTAAAGCCAAAAAGGTGATAAAGCCGAT
+AATACCGAGCATCATCCACGGTAGTTCANNCTGCGCAAGCGCTTTACCCATATCAAACAA
+CCAGCCGCCGCCGATATAACTAATCGCGNNGCCAATGGCTAATCCCAGACGGCTAAAGCC
+CATATAGCTTCCCCGCGCCCTCGCGTCCNNGGGCGACGCGCTGAGCGTTTCGCGCGCCGG
+TTCGGCGATAACCGAGCCGATGTAGAAANNGCAAATAAGCGTAAAAAGCTGCTGTAAATT
+GCCCACCATCCCGATGGGGAGCATGCTCNNCGACATGACGAGCAAACCGGCCATCAGCCG
+ATGCTCCAGCCGAAAACGCTTTTCGCTCNNGCGGGCAATCGGGTAGAGCAACGTCAGCGA
+GAGACACGCCTCAATAGCGTACATCCATNNCACGGCAGCAGGCGAACCGGCGATATCGTT
+TACCATAATCGGCAGCATTAACATGACCNNTACCGCCAGCATATAGTAGCCCGCCAGCGT
+CAGCACGTAGGTGACAAACCTTTTATTGNNCATGACGCGGCGCATTCCTTCACGCACCGG
+CGTTCTGGCCGTTGATAGCTTCCAGGCCNNAAGCAGCCATGCGTTGAAAAGGGCGCATAA
+TATGAACAAAATAGCGCCCGTCGCGCAGNNCAGGCGAAAATCGTATTGTAGCAACCAGCT
+TCCCAGCAGCGCGCCAATCACCGCGCCCNNGCTGTCCTGCATCATCAACAGAGAGAAGAA
+GCGGCCCCGTTGCTCCGGACGAATTAATNNGACCACCAGCGCTGAACGCGGCGGGTCGAA
+AAGCGTACCGCCGAGACCGGAAAGAAAGNNGGAAAACCACAAGAGCCAGGGCTCATGCGC
+GATACCCATGGTGGCAAAGCCTGCGGCGNNCATCAGCATACCGGTGACAATCATCGGTTT
+CGCGCCAAAGCGATCGGCGATGGCGCCGNNAAAAATGCCCAGACCTTGTTGAATAAACTG
+ACGCAGGCCGAGCGCGATCCCTACCATTNNGGCAGCCCACCCCATTTGATCGACAAAGCG
+AATAGAGATGAGCGGGAAGACGACGAAANNACCCAGCACCACTAACATGTTATCGATGAG
+AAGAAAATATTTACCCAGGTTCCTCGCCNNCGAGACGCGCGACATTTCCCCTCCCGGGAA
+ATAAAAGATGAGCGTCTTCTATTCTGCGNNGGCGTTTCGTTTTTTCCTACCGTTAGCGGG
+ACAATATTTTTTTATCAAAAGTCCTTTTNNATCGAGAGTTTTCATCAAAATGTGGCAGCA
+ATTCAAAAAATGACGATTTGCGCTTTTCNNAGGGCCTGGTTGCGCAGGTATAGTAATGTT
+ACTGGCGTGCTGAAGACGTTACAGGAAGNNGTAGGTATAGAATGTTTGGCTATCGCAGTA
+ACGTGCCAAAAGTGCGCTTAACCACCGANNGTCTGGTGGTACGTTTAGTGCATGAGCGTG
+ATGCCTGGCGTCTGGCCGATTATTACGCNNAAAATCGTCATTTTTTAAAACCCTGGGAAC
+CGGTCCGTGATGAAAGTCATTGTTATCCNNCAGGATGGCAGGCGCGTCTGGGAATGATCG
+GTGAATTTCACAAACAGGGCTCCGCCTTNNATTTCGCGCTACTTGATCCGGAAGAAAAAG
+AAATTATCGGCGTGGCGAATTTTTCCAANNTGGTGCGCGGTTCTTTTCATGCCTGTTATC
+TGGGCTATTCCATTGCGCAAGAGTGGCANNGGCAAGGGCTGATGTTTGAAGCCTTAACCG
+CTGCGATTCGCTATATGCAGCGCACTCANNATATCCACCGTATCATGGCGAACTATATGC
+CGCACAACAAACGTAGCGGCGCGTTGCTNNCGCGGCTTGGCTTTGAAAAAGAAGGCTATG
+CGAAAGATTACCTGTTGATTGATGGACANNGGCGCGACCATGTCCTGACGGCGTTAACCA
+CGCCGTTATGGACGCCGGGGCGTTGAGCNNCTTACGGAATGAGAGGCAAAGGGAGAAAAC
+GATGAAATATGAATTAACCGCCACTGAANNGCGAGTGATTGGCTGTCTGCTGGAAAAGCA
+GGTGACAACGCCGGAACAGTATCCGCTTNNCGTCAACGGGGTGGTGACAGCCTGTAATCA
+GAAAACCAACCGTGAACCGGTGATGAACNNGACGGAACAAGAGGTACAAGAACAGCTCGA
+TAACCTGGTGAAACGCCACTTTTTGCGTNNGGTCAGCGGGTTTGGCAACCGCGTCACCAA
+ATATGAACAGCGCTTCTGTAATTCCGAANNTGGCGATCTGAAACTTAGCGCGGCGGAAGT
+GGCGCTCGTCACTACGTTGCTGCTGCGCNNCGCGCAAACGCCCGGCGAGTTGCGTAGCCG
+GGCGTCGCGGATGCATGAATTCAGCGATNNGGCGGAAGTTGAATCCACGCTGGAACGGCT
+TGCCAGTCGTGAGGACGGCCCGTATGTCNNCCGTCTGGCGCGTGAACCGGGTAAGCGCGA
+AAGCCGCTATATGCACCTTTTTTGCGGCNNCGTCGATGAACTGTCTCTCCAGACGTCTGC
+GCCGGAAAGTGCGTCGGGCGATCTTCAGNNGCGCGTCGAAGCGCTGGAAAGCGAAGTGGC
+GGAGTTAAAGCAGCGGCTGGATTCTTTGNNAGCTCACCTGGGAGAGTAATGTGAGAACAT
+TACGGATTGGCATTGTCGTGTTAGGTGGNNTTGCGCAGAAGGCCTGGCTGCCGGTATTAA
+CCAACACCGCCGGATGGACGTTACAGGGNNCCTGGTCTCCTTCGCGGGATAAAGCCTTAC
+GTATTTGCGAAAGCTGGCGCATACCGTANNTGGATTCGCTGGCGAATTTAGCGTCCGGCT
+GCGATGCGGTCTTCGTCCACTCCAGTACNNCAAGCCATTATGCCGTGGTCAGCGAACTTC
+TCAACGCTGGCGTCCATGTCTGCGTGGANNAACCGCTGGCGGAAAATCTACGTGATGCCG
+AACGGCTGGTGGCGCTGGCGGCGCAAAANNAATTGACGCTGATGGTTGGCTTTAATCGCC
+GTTTCGCGCCGCTGTACCGCGAACTGAANNCGCGCCTCGGCACTGCGGCGTCACTGCGTA
+TGGATAAACATCGTACCGATAGCATCGGNNCGCATGACTTACGTTTTACTTTGCTCGATG
+ACTATCTGCATGTCGTGGATACCGTTCTNNGGCTGGCGGGCGGCGAGGCGCGCCTTGCCA
+GCGGCACGTTGCTCACCAGCGAGTCCGGNNAAATGTGCTATGCGGAACATCATTTTTCCG
+CCGACAAATTACAAATTACCACCAGTATNNACCGGCGCGCCGGAAGTCAGCGTGAATCGG
+TCCAGGCCGTCACCGATGGCGGGCTGTANNACGTGACGGATATGCGTGAATGGCGCGAAG
+AGCGCGGGCAGGGTATTCTCATCAAACCNNTTCCGGGTTGGCAAACAACGCTTGAGCAGC
+GTGGTTTTGTCGGATGCGCGCGGCATTTNNTTGACTGCGTACAAAATCAGACGGTTCCGG
+AAACGGCGGGGGAGCAGGCGATTTTGGCNNAGCGCGTCGTGGAGGCGCTGTGGCGGGACG
+CCATCAGCGAATAATCCTCTGTAACATCNNGCGGTAGTAATTCATCGTAATCCAGGTACT
+ATACCCTCAATAATTCGAGTTGCAGAAANNCTAACGCACATGCAGCTCGAAGTATGGCGG
+GTATATATGCCCACTCTACATAATACCTNNTTTCACAGTGAATAATGGCAAACCGTGGGG
+AGTCTGTAAGGCCTGATAAGACGTTTTGNNGTCGCCGTCAGGCGCAGTGATACAGCCGGA
+TACGGCAGAAGTTGCGTTATCCGGTCGANNGATCAGCCATGCAGGAGTTTTACGCCAGGG
+TCTGGAATACAAAAGAAATGAATTTATTNNAATCGCTGGCTGCCGTCAGCTCGATGACTA
+TGTTTTCACGCGTGTTGGGCTTTGCCCGNNATGCGATTGTCGCCAGAATTTTTGGCGCAG
+GGATGGCGACCGACGCCTTTTTTGTGGCNNTTAAACTTCCCAATCTACTACGCCGGATCT
+TTGCCGAAGGCGCTTTTTCTCAGGCCTTNNTGCCTATCCTGGCGGAATATAAGAGCAAGC
+AGGGTGAAGAAGCGACGCGGATCTTTGTNNCTTACGTTTCCGGCCTGTTGACGCTGGCAT
+TGGCCGTCGTGACGGTGGCCGGTATGCTNNCCGCCCCGTGGGTGATTATGGTAACCGCGC
+CGGGTTTTGCCGATACTGCGGATAAATTNNCGCTGACGACGCAACTGCTGCGGATTACGT
+TTCCCTATATTCTGCTGATCTCGCTGGCNNCACTGGTTGGCGCCATTCTCAACACCTGGA
+ATCGCTTCTCTATTCCCGCTTTTGCGCCNNCATTTCTTAATATCAGTATGATCGGTTTTG
+CATTATTCGCCGCGCCATACTTTAATCCNNCGGTGCTGGCGTTAGCCTGGGCAGTCACCG
+TCGGCGGCGTGCTGCAACTGGTGTATCANNTTCCGTATTTGAAAAAGATCGGTATGCTGG
+TGCTGCCGCGCATTAACTTTCACGACACNNGGGCGATGCGGGTGGTCAAACAGATGGGGC
+CGGCGATTTTGGGCGTTTCCGTCAGTCANNTCTCCCTTATCATCAATACCATTTTCGCCT
+CGTTTCTGGCCTCCGGCTCGGTCTCATGNNTGTACTATGCCGATCGGTTGATGGAGTTCC
+CGTCCGGCGTGCTGGGCGTGGCGTTGGGNNCCATCCTGTTGCCGTCATTGTCGAAAAGCT
+TTGCCAGCGGCAATCATGATGAGTACTGNNGCCTGATGGACTGGGGGCTGCGTTTGTGCT
+TTTTACTGGCGTTGCCGAGCGCGGTAGCNNTAGGCATTCTGGCGAAGCCGCTGACGGTCT
+CGCTGTTTCAGTACGGTAAATTCACCGCNNTTGATGCGGCGATGACGCAGCGGGCGTTAA
+TCGCCTATTCGGTGGGGCTGATTGGCTTNNTCGTCGTAAAAGTGCTGGCCCCGGGCTTCT
+ATTCTCGCCAGGATATTAAAACGCCGGTNNAAATCGCCATCGTGACGTTAATCATGACGC
+AGTTAATGAACCTGGCGTTTATTGGACCNNTGAAACACGCCGGGCTGTCGCTCTCTATTG
+GTCTGGCGGCATGTCTCAATGCGTCGCTNNTGTACTGGCAACTGCGCAAACAGAATATCT
+TTACGCCACAACCGGGGTGGATGTGGTTNNTGATGCGTCTGATCATTTCCGTACTGGTAA
+TGGCCGCCGTGTTGTTCGGCGTGTTGCANNTTATGCCGGAGTGGTCGCAAGGGTCGATGC
+TATGGCGTTTGCTGCGTTTGATGGCGGTNNTGATCGCGGGTATCGCGGCCTATTTCGCCG
+CGCTTGCCGTGCTGGGCTTTAAAGTGAANNAGTTTGTTCGCCGGACGGCGTAAATTCAGT
+GCCTGATAGCGCTGTGCTATCAGGCCTANNAGGCATTCAGGCCGGAAAGGCGCAACGTCG
+CCATCCGGCAATGATTAGATAGATATTTNNTTACCGCCGCGGTGAGAGACGGAAGTCTGA
+CCGTCAGCCCCGTACAAGGTCGGCTCCTNNTGAGGTTTCAGCACCTCCAGCGCCTGTTGA
+TTACGCTCGATTTGCCCTTCCAGCAGCCNNCCGTTGTGCTGGTTGAGGTCGCGCAGATGC
+TGCGTTTTTTCGGTAATCGCCTGCCAGCNNTCTGCAATGTCATCGTTTGCGCTACGCTGC
+GCGTTCTGCTCCAGACGGCGCTGTTGTTNNAGATAATCCAGCGTCGCCAGCAACGAGCTT
+TTTTCTTCTGTAATACGCTGTAGCTGGCNNCCGTTAATCTGGCCTACGGAAAGCTGTTGT
+TGCTCGGCGTCCATCACCGTCTTCAGGTNNTTCAGGACGGTGGTCATCTGGTCAAGTATT
+TCTGACAAACGAGTCATACGCTTATTTANNCTGTAAGTAGCTCTGCGCCTCGCGAATGAG
+CGAGTCTGCTATTTTTCCCGTATCCATTNNTAACTCACCGTTACGGATAGCCGTTTTTAA
+TGCTTCGACGCGTTCCATATTAATGTCGNNGACGCCTGGCTGCATAAGCTTCGCTTGCGC
+GTCGCTTAACGTTACGCTGGCGCTCGTCNNGGCGGACGTTTTTTCCTGACGCGTTTTTTG
+TACCGGCGTGTCGCTGGTTTCGCGCGTCNNGACAGTGCTAACGGGTTTCAAAGGTGAGGT
+ACGGTCAATGCTCATTTATTTATCCTCANNGAGGGTTACGTTGTAGCGGCCAGCTACCAT
+CATGGTTGAATATCTCATCGGCAGCCGCNNCAAAATCTTTACACAATTATAGGTTAATAA
+GAATATTCCCATCAGAATCGACGGTTCCNNTCACGATTTGACCCGATGTCATGCGCACGC
+GCGCATTTTGCGCGACGGCGGCATTATTNNTCGCCTGACCTTCCGCATTGACGCTAAACC
+CCTCGCCATTGGCGATGACCTGTACTCGNNGACCCGCTTTGACACGCCAGGCCTGACGTA
+TCATCGTAAGCTGTACCGGCTGCCCGGGNNCGAGATCGCGCAAACTGACGGCATCCTGAA
+TCTGACGGATATCCAGTACCGTCCGCGGNNGTAACTGATCCAGTCTGCCACGTTTTAGCG
+TGACGTTGGCCGGCGTCAATTTTCCGCCNNGCGCGACGGGCGCGGCTACGGCGACATAAT
+TGCCGGTCGCTTGCACATTCACCTGCAANNAACGTTTTTCATTGGCGCAGCGCGCCACCA
+CATTGACGTTGCCCCACAGCTTCGCGCTNNCCGTCATGCTGAAGGCTGGCTGCTCGCAGC
+TCGGTAGCAGATTGGGCGGTGAACGGAGNNTGACAACCACCTCGTCGCTGAAGCCAGCCA
+GACGCTGGGAAAACCACGTGGTCAGCTGNNCGTTGATGTCCTGCGCCATTGTCAGGGGGC
+TGAACAGCAAAGCCGCCACGGCGAATCCNNGTTTTAACGTTTGCATGGTACTTCCCCCTG
+GTTGATGTCATGACAGGATTCTACCCGTNNGAAGCAAGCATCAACGCAATAAATAGCGAC
+GCATTTTGCGTTTATTCCGGCGATAACGNNCGCGTGAAGGCATTTAAGCTGTCGGCTGAA
+TTTTGCCATTTGCGGAGGAGATATGCTCNNCAGGCTCGATGCCGCCTTACGATTTCAGCA
+GGAAGCGCTAAATCTGCGCGCGCAACGTNNGGAAATATTAGCGGCGAATATCGCCAATGC
+CGATACGCCGGGGTATCAGGCGCGCGATNNTGATTTTGCCAGTGAGTTAAAAAAAGTGAT
+GGTGCGCGGACGGGAAGAAACCGGCGGCNNCGCGTTGTCGTTGACTTCTTCTCGCCATAT
+TCCCGCCCAGGCGGTCTCTTCTCCCGCANNGGATCTGCTTTACCGCGTACCCGATCAGCC
+TTCTTTGGATGGTAACACCGTAGATATGNNCAGGGAACGTACGCAGTTTGCGGATAACAG
+TCTCAAATATCAGATGGGGCTTACCGTTNNGGGTAGCCAACTCAAAGGCATGATGAATGT
+GCTACAGGGAGGAAACTAATTCGTGGCGNNGTTAAACATTTTTGATATTGCCGGATCGGC
+GCTTGCCGCACAGTCCAAGCGGTTGAACNNTGCGGCCAGTAACCTTGCGAATGCGGATAG
+CGTCACCGGCCCGGACGGACAGCCTTATNNCGCCAAACAGGTGGTTTTTCAGGTGGACGC
+CGCGCCGGGTCAAGCCACTGGCGGGGTANNGGTCGCCAGCGTGATTGAAAGTCAGGCACC
+GGAAAAGCTGGTTTATGAGCCAGGCAATNNGCTGGCGGACGCTAATGGTTACGTCAAAAT
+GCCCAACGTCGATGTGGTCGGCGAAATGNNCAACACGATGTCAGCCTCGCGCAGCTATCA
+GGCAAATATCGAAGTCCTGAATACCGTANNAAGCATGATGCTTAAAACGCTGACATTAGG
+CCAGTAAAGGAGGCGCGTATGTCTATTGCCGTAAATATGAATGACCCGACCAACACGGGC
+GTCAAAACGACGACCGGCAGCGGGTCGATGACCGGAAGCAACGCTGCCGATCTGCAAAGC
+AGTTTCCTGACCTTACTGGTCGCGCAATTGAAGAACCAGGACCCGACTAACCCATTACAA
+AATAATGAGTTAACGACACAGTTGGCGCAAATCAGTACCGTGAGCGGCATTGAAAAACTG
+AATACGACGCTGGGGGCTATTTCCGGGCAAATCGATAATAGTCAGTCCCTACAGGCGACC
+ACGCTGATTGGACATGGCGTTATGGTGCCTGGCACCACAATTCTGGCGGGTAAAGGCGCG
+GAAGAAGGGGCCGTGACGTCCACGACGCCGTTTGGCGTGGAATTGCAACAGCCTGCGGAC
+AAAGTGACGGCAACCATTACCGATAAAGATGGCCGGGTGGTACGGACGCTGGAGATCGGT
+GAGTTGCGAGCCGGGGTACACACCTTTACCTGGGATGGTAAGCAAACGGACGGAACAACG
+GTACCGAATGGTTCTTACAACATTGCGATTACCGCCAGCAATGGCGGGACGCAACTGGTG
+GCGCAGCCGCTGCAATTCGCTCTGGTACAGGGCGTGACGAAGGGCAGTAACGGCAACCTG
+TTGGATCTGGGTACCTACGGCACCACCACACTCGACGAAGTTCGGCAAATAATCTAAGCC
+CTTACACTTATCAGGAGTCAGTCATGTCTTTTTCTCAAGCGGTTAGCGGCCTGAACGCTG
+CGGCCACCAACCTTGATGTTATCGGTAATAACATCGCCAACTCCGCCACCTATGGCTTTA
+AGTCCGGTACGGCATCATTTGCCGATATGTTCGCCGGTTCCAAAGTGGGGTTGGGCGTAA
+AAGTGGCGGGGATTACCCAGGATTTTACCGACGGTACGACAACGAACACCGGGCGCGGGC
+TGGATGTCGCGATTAGCCAGAACGGTTTTTTCCGCCTGGTAGACAGCAACGGTTCCGTGT
+TCTATAGCCGCAACGGCCAGTTCAAACTGGACGAGAACCGTAACCTGGTCAATATGCAGG
+GGATGCAGTTGACCGGCTATCCGGCCACCGGTACGCCGCCGACCATTCAGCAGGGGGCGA
+ATCCTGCGCCGATCACCATTCCGAACACGCTGATGGCGGCGAAATCGACCACCACCGCGT
+CAATGCAGATCAACCTGAACTCAACGGACCCTGTACCGTCTAAAACGCCCTTTAGCGTGA
+GTGATGCGGATTCGTATAACAAAAAAGGCACCGTCACCGTTTATGACAGCCAGGGTAATG
+CCCATGACATGAACGTCTATTTTGTGAAAACCAAAGATAATGAATGGGCTGTGTACACCC
+ATGACAGCAGCGATCCTGCAGCCACTGCGCCAACAACGGCGTCCACTACGCTGAAATTCA
+ATGAAAACGGGATTCTGGAGTCTGGCGGTACGGTGAACATCACCACCGGTACGATTAATG
+GCGCGACAGCGGCCACCTTCTCCCTCAGCTTCCTTAACTCCATGCAGCAGAACACCGGGG
+CTAATAACATCGTCGCCACCAATCAAAACGGCTATAAGCCTGGCGACCTGGTGAGCTACC
+AGATTAACAATGATGGCACCGTGGTTGGCAACTACTCCAACGAGCAGGAGCAGGTGCTGG
+GGCAGATTGTGCTGGCTAACTTCGCCAACAACGAAGGTCTGGCATCCCAGGGCGATAACG
+TCTGGGCGGCGACGCAGGCCTCCGGGGTAGCGCTGCTGGGGACTGCCGGTTCCGGCAACT
+TCGGTAAGCTGACGAACGGCGCGCTGGAAGCCTCTAACGTGGATTTGAGTAAAGAGCTGG
+TGAATATGATCGTCGCGCAGCGTAACTACCAGTCGAATGCGCAGACCATCAAAACCCAGG
+ACCAGATCCTCAATACGCTGGTTAACCTGCGCTAAGCGCCTGACGGGATAGCTTAATGGA
+TCACGCAATTTATACCGCCATGGGGGCGGCCAGCCAGACGCTTAACCAGCAGGCGGTAAC
+GGCCAGCAACCTGGCTAATGCCTCAACGCCGGGCTTTCGCGCGCAGCTTAACGCGCTACG
+CGCGGTGCCCGTTGATGGCCTCTCTTTAGCGACGCGCACGTTGGTTACGGCGTCGACGCC
+GGGGGCGGATATGACCCAGGGTCAGTTGGACTACACTTCCCGCCCGCTGGATGTTGCGTT
+ACAGCAGGACGGCTGGCTGGTGGTGCAAGCGGCGGATGGCGCTGAAGGATATACCCGTAA
+CGGGAATATCCAGGTGGGCCCGACCGGGCAGTTAACCATTCAGGGACATCCGGTTATCGG
+CGAAGGCGGCCCGATTACCGTTCCGGAAGGGTCGGAAATCACCATTGCGGCAGACGGCAC
+GATCTCCGCGCTCAATCCCGGCGACCCGCCAAACACGGTGGCGCCCGTTGGGCGGCTGAA
+GCTGGTCAAAGCGGAAGGCAATGAGGTGCAGCGGAGCGATGACGGTTTATTCCGCCTTAC
+CGCCGAGGCACAGGCTGAACGCGGGGCGGTACTGGCCGCCGACCCGTCAATTCGCATTAT
+GTCGGGCGTGCTGGAGGGCAGTAACGTCAAGCCGGTTGAAGCCATGACCGACATGATCGC
+CAACGCACGTCGTTTTGAAATGCAGATGAAGGTTATCACCAGCGTAGATGAGAACGAAGG
+GCGAGCTAACCAACTGCTGTCGATGAGTTAATACAGGACATTTTATGATCAGTTCATTAT
+GGATCGCCAAAACCGGTCTGGACGCGCAGCAAACCAATATGGATGTGATTGCCAATAACC
+TGGCAAACGTCAGCACCAATGGTTTTAAGCGTCAGCGCGCGGTATTTGAAGATCTGTTGT
+ATCAGACCATCCGCCAGCCGGGCGCGCAGTCGTCCGAGCAGACGACGCTGCCTTCCGGGC
+TGCAAATCGGTACCGGCGTGCGTCCGGTCGCCACGGAGCGCCTGCACAGTCAGGGGAACC
+TGTCGCAGACCAACAACAGTAAAGATGTGGCGATTAAAGGGCAGGGCTTTTTCCAGGTCA
+TGCTGCCGGACGGTACGTCTGCCTATACCCGCGACGGCTCTTTCCAGGTGGATCAGAATG
+GTCAACTGGTGACGGCGGGCGGTTTTCAGGTGCAGCCGGCAATCACCATTCCGGCCAACG
+CGTTAAGCATCACGATTGGCCGCGACGGCGTGGTCAGCGTTACCCAGCAAGGGCAGGCCG
+CGCCGGTTCAGGTCGGGCAGCTTAACCTGACCACCTTTATGAACGACACCGGTCTGGAAA
+GCATCGGCGAGAACCTCTATATCGAAACGCAATCGTCCGGCGCGCCGAACGAAAGCACGC
+CGGGGCTCAACGGCGCGGGGTTGTTGTATCAAGGGTATGTCGAAACGTCGAACGTTAACG
+TGGCGGAAGAGCTGGTGAACATGATTCAGGTTCAACGCGCCTATGAAATTAACAGTAAAG
+CAGTATCGACGACCGATCAGATGCTGCAGAAACTGACGCAACTCTAAGGGGCCGCCGGTG
+GGGGATACGCCACCGGCTCCCTGATTTTGAAGATGAAGGTAATGCAAAAATACGCGCTTC
+ACGCTTACCCAGTTATGGCCCTGATGGTCGCGACGCTGACAGGATGCGCCTGGATACCCG
+CTAAACCGCTCGTGCAGGGGGCGACCACGGCGCAGCCGATACCTGGCCCGGTACCGGTGG
+CGAATGGCTCCATATTTCAGTCTGCGCAGCCGATTAATTATGGCTATCAGCCGCTTTTTG
+AAGATCGTCGACCGCGTAATATCGGCGATACGCTCACGATTGTGTTACAGGAAAACGTCA
+GCGCCAGTAAAAGCTCGTCGGCAAATGCCAGCCGCGACGGCAAAACCAGCTTTGGTTTTG
+ATACGGTACCGCGTTATCTGCAGGGATTATTCGGTAATTCCCGCGCGGATATGGAGGCCT
+CCGGCGGCAACTCTTTTAATGGTAAAGGCGGCGCGAATGCCAGCAATACCTTTAGCGGCA
+CGCTGACCGTGACCGTCGATCAGGTTCTGGCCAATGGCAATTTACACGTCGTGGGGGAAA
+AACAGATCGCGATTAATCAGGGAACGGAATTCATCCGCTTCTCCGGCGTGGTAAATCCAC
+GCACCATCAGCGGTAGCAACTCTGTTCCCTCGACACAGGTGGCGGATGCGCGGATTGAAT
+ATGTCGGGAACGGCTATATTAACGAAGCGCAAAATATGGGCTGGCTGCAACGTTTCTTCC
+TTAATTTGTCGCCGATGTAAGCGAGGTGTATGTGTTTAAAGCTCTTGCAGGAATCGTTCT
+GGCACTGGTTGCCACTCTGGCGCACGCCGAGCGTATCCGGGATCTGACCAGTGTCCAGGG
+AGTACGGGAAAACTCGCTGATCGGCTACGGGCTGGTGGTCGGGCTGGACGGTACGGGCGA
+CCAGACGACCCAGACGCCATTTACCACCCAGACGCTGAATAACATGCTGTCACAACTGGG
+GATTACGGTCCCCACCGGCACCAATATGCAGTTGAAAAACGTGGCGGCGGTGATGGTGAC
+GGCGTCGTATCCGCCTTTTGCGCGACAGGGACAAACGATCGATGTCGTCGTTTCCTCAAT
+GGGGAACGCTAAAAGTCTGCGTGGCGGGACGTTATTAATGACGCCGTTAAAAGGGGTGGA
+CAGCCAGGTGTATGCTCTGGCGCAGGGCAATATTCTGGTCGGCGGCGCGGGCGCTTCCGC
+AGGCGGCAGTAGCGTGCAGGTTAACCAGCTTAATGGCGGGCGCATCACTAATGGCGCGAT
+TATCGAACGCGAGTTGCCGACTCAGTTCGGCGCTGGCAACACCATTAATCTGCAATTGAA
+CGACGAAGATTTTACGATGGCGCAGCAAATTACCGACGCCATCAACCGCGCCCGCGGTTA
+CGGCAGCGCCACTGCGCTTGATGCGCGAACGGTACAGGTACGCGTGCCCAGCGGCAACAG
+CTCGCAGGTGCGTTTTCTGGCGGACATTCAAAATATGGAAGTCAACGTGACGCCGCAGGA
+TGCAAAAGTCGTGATCAACTCGCGTACCGGTTCGGTGGTCATGAATCGGGAAGTCACGCT
+GGATAGCTGCGCTGTGGCGCAGGGCAATTTGTCAGTGACAGTCAATCGCCAACTCAACGT
+CAACCAGCCGAATACGCCATTTGGCGGCGGGCAGACCGTGGTGACGCCACAGACTCAGAT
+AGATTTGCGTCAGAGCGGCGGATCGCTACAGAGCGTGCGTTCCAGCGCCAATCTGAACAG
+CGTAGTGCGCGCGCTGAATGCGCTTGGCGCGACGCCGATGGATCTGATGTCGATTTTGCA
+GTCCATGCAGAGCGCGGGCTGTCTACGCGCCAAACTGGAAATCATCTGATGATCGGAGAC
+GGTAAATTGCTGGCCAGCGCGGCCTGGGATGCGCAATCTCTGAACGAACTGAAAGCGAAA
+GCGGGCCAGGACCCGGCGGCGAATATCCGTCCTGTGGCCCGTCAGGTGGAAGGGATGTTT
+GTGCAGATGATGCTGAAAAGTATGCGCGAGGCTTTACCCAAAGATGGTTTATTCAGCAGC
+GATCAGACGCGTCTGTATACCAGCATGTATGACCAGCAGATCGCCCAGCAGATGACCGCC
+GGTAAGGGATTGGGGCTGGCGGATATGATGGTTAAACAGATGACGGGCGGGCAGACGATG
+CCTGCAGATGATGCGCCGCAAGTACCGCTTAAATTCTCCCTGGAGACGGTAAACAGCTAT
+CAAAATCAGGCGCTGACCCAACTGGTGCGCAAAGCCATACCGAAAACGCCGGACAGCAGC
+GATGCGCCGCTCTCCGGCGACAGTAAAGACTTTCTGGCCCGGCTTTCGCTCCCGGCGAGG
+CTGGCCAGCGAACAAAGCGGGGTGCCGCATCATCTGATTCTGGCGCAGGCGGCGCTGGAG
+TCCGGCTGGGGGCAGCGGCAAATCCTGCGGGAGAATGGCGAACCCAGCTATAACGTATTT
+GGCGTGAAAGCGACCGCCAGTTGGAAAGGGCCGGTGACGGAAATCACCACCACTGAATAC
+GAAAATGGCGAAGCGAAAAAAGTGAAAGCGAAATTCCGCGTCTATAGCTCGTATCTGGAG
+GCGTTATCGGATTATGTCGCGCTGTTAACGCGTAACCCACGCTACGCTGCCGTGACCACT
+GCCGCCACGGCAGAGCAGGGCGCAGTGGCTCTGCAAAACGCCGGATACGCCACTGACCCG
+AATTACGCGCGTAAATTGGCCAGCATGATTCAGCAGTTGAAAGCGATGAGTGAAAAGGTC
+AGCAAAACCTACAGCGCGAATCTCGACAATCTCTTTTAAATTGCTCAAGTCCACGTAGTC
+GCTGCCGATAACAACGAGTATTGAAGGATTAAAAGGAACCATCATGTCCAGCTTGATTAA
+TCACGCCATGAGCGGACTTAACGCCGCGCAGGCCGCGTTAAATACGGTCAGTAATAACAT
+CAACAATTATAACGTTGCGGGTTATACCCGGCAGACAACTATTCTGGCGCAGGCAAACAG
+TACGTTAGGGGCTGGCGGCTGGATAGGTAATGGCGTTTACGTTTCAGGCGTACAGCGCGA
+ATATGATGCGTTTATCACTAATCAGCTACGCGGCGCGCAAAACCAGAGCAGCGGCTTAAC
+CACGCGCTATGAACAAATGTCGAAAATCGACAACCTGCTGGCCGATAAATCCAGCTCACT
+GTCTGGCTCGCTGCAGAGTTTTTTTACCAGCCTGCAAACGTTAGTCAGTAATGCGGAAGA
+TCCTGCGGCGCGTCAGGCGCTGATTGGTAAAGCGGAAGGGCTGGTAAACCAGTTCAAAAC
+CACCGATCAGTATCTGCGCGATCAGGATAAACAGGTCAATATCGCGATTGGCTCCAGCGT
+GGCGCAAATCAACAATTACGCGAAGCAGATAGCTAACCTGAACGATCAAATCTCCCGTAT
+GACGGGCGTAGGCGCGGGCGCATCGCCGAACGACCTGCTCGATCAACGTGATCAGTTGGT
+TAGCGAGCTTAACAAGATCGTTGGCGTCGAGGTGAGTGTACAGGACGGCGGCACCTATAA
+CCTGACGATGGCCAATGGCTATACGCTGGTGCAGGGGTCGACGGCGCGTCAGTTGGCGGC
+GGTTCCCTCCAGCGCCGACCCGACGCGAACGACTGTCGCTTATGTCGATGAGGCCGCCGG
+TAACATCGAAATTCCGGAAAAGTTGCTGAACACCGGTTCGCTCGGCGGGCTACTGACGTT
+CCGTTCTCAGGATCTGGATCAGACTCGTAATACGCTGGGCCAGTTGGCGTTGGCGTTTGC
+CGATGCGTTTAACGCGCAGCATACCAAAGGTTATGACGCCGACGGCAATAAAGGGAAAGA
+CTTCTTTAGCATTGGCTCGCCGGTGGTATATAGCAACAGTAATAATGCCGATAAAACGGT
+ATCGCTAACCGCTAAGGTGGTCGACAGCACGAAGGTTCAGGCGACGGATTATAAGATTGT
+TTTTGACGGTACAGACTGGCAGGTTACTCGCACTGCGGATAACACCACCTTCACGGCAAC
+AAAAGATGCTGACGGAAAACTGGAGATTGACGGTCTGAAAGTGACGGTAGGGACTGGCGC
+ACAGAAAAACGACAGTTTTCTTCTCAAGCCGGTCAGCAATGCTATCGTCGACATGAACGT
+TAAAGTGACAAATGAAGCCGAGATTGCGATGGCGTCTGAGTCAAAACTCGATCCTGATGT
+GGATACCGGCGACAGCGATAACCGCAATGGTCAGGCATTGCTGGACTTACAAAACAGCAA
+TGTAGTGGGCGGCAACAAAACCTTTAACGATGCTTACGCCACGTTGGTCAGCGATGTGGG
+TAACAAAACGTCAACGCTGAAAACCAGCAGCACCACGCAGGCGAATGTGGTTAAACAGCT
+TTATAAACAGCAACAGTCGGTTTCCGGCGTTAACCTCGACGAAGAGTACGGCAATTTGCA
+GCGTTATCAGCAGTATTATCTGGCGAATGCGCAAGTATTGCAGACCGCGAATGCGCTGTT
+TGATGCGTTATTGAATATTCGCTAAAGGAGAAGGATGACATGCGTATCAGTACCCAGATG
+ATGTACGAACAAAATATGAGCGGCATCACTAATTCTCAGGCCGAATGGATGAAGCTGGGC
+GAGCAGATGTCTACCGGTAAGCGCGTTACCAACCCATCTGACGATCCGATCGCCGCGTCG
+CAGGCGGTAGTACTCTTTCAGGCGCAGGCGCAGAATAGCCAGTACGCCCTGGCGCGTACG
+TTTGCCACCCAAAAAGTGTCGCTGGAAGAAAGCGTACTCAGTCAGGTGACGACGGCGATT
+CAAACCGCGCAGGAAAAAATCGTCTATGCCGGAAACGGCACGTTAAGCGACGATGACCGC
+GCGTCGCTGGCGACGGATTTACAGGGGATCCGCGATCAGCTGATGAACCTGGCAAACAGC
+ACTGACGGCAATGGTCGCTATATCTTTGCCGGGTATAAAACGGAAGCGGCGCCATTCGAC
+CAGGCGACAGGTGGTTATCATGGCGGCGAGAAAAGTGTTACCCAGCAGGTGGATTCCGCA
+CGCACGATGGTAATTGGCCATACGGGAGCGCAAATTTTTAATAGCATCACCAGCAATGCG
+GTGCCGGAACCGGATGGCTCGGACTCCGAAAAGAATCTGTTTGTCATGCTCGATACGGCA
+ATTGCCGCGCTCAAGACCCCGGTGGAAGGCAATGACGTGGAAAAAGAAAAAGCCGCTGCC
+GCCATTGATAAAACCAATCGCGGCTTAAAAAATTCGCTTAATAACGTCCTGACCGTTCGT
+GCGGAACTGGGAACGCAACTGAGCGAACTCAGTACGCTGGATTCACTGGGAAGCGACCGT
+GCGCTGGGACAGAAGCTACAGATGAGCAACCTGGTAGATGTGGACTGGAACTCGGTCATT
+TCCTCCTACGTCATGCAACAGGCGGCATTACAGGCGTCCTATAAAACGTTTACCGACATG
+CAGGGAATGTCGCTTTTCCAGTTGAACCGGTAACGCCTCTTTTTGAAACATATCACGAAA
+CTGGATATGTTTTGTCTGCCCGCGCCATCCACCCCGGCGCGGGCATTTTTTGTCTATGGA
+AAACCCCCAGCTAGGCTGGGGGTTCCGGAAAGCTTTCAGCTTTAAGCCAGTTATTAAAAC
+CCCTTTTGATTTGTTAAAACATCTTGCGGTCTGGC
\ No newline at end of file
diff --git a/t/data/real_data_core_gene_alignment.aln b/t/data/real_data_core_gene_alignment.aln
new file mode 100644
index 0000000..e23823b
--- /dev/null
+++ b/t/data/real_data_core_gene_alignment.aln
@@ -0,0 +1,1950 @@
+>11111_1#11
+ATGCGTATCAGTACCCAGATGATGTACGAACAAAATATGAGCGGCATCACTAATTCTCAG
+GCCGAATGGATGAAGCTGGGCGAGCAGATGTCTACCGGTAAGCGCGTTACCAACCCATCT
+GACGATCCGATCGCCGCGTCGCAGGCGGTAGTACTCTTTCAGGCGCAGGCGCAGAATAGC
+CAGTACGCCCTGGCGCGTACGTTTGCCACCCAAAAAGTGTCGCTGGAAGAAAGCGTACTC
+AGTCAGGTGACGACGGCGATTCAAACCGCGCAGGAAAAAATCGTCTATGCCGGAAACGGC
+ACGTTAAGCGACGATGACCGCGCGTCGCTGGCGACGGATTTACAGGGGATCCGCGATCAG
+CTGATGAACCTGGCAAACAGCACTGACGGCAATGGTCGCTATATCTTTGCCGGGTATAAA
+ACGGAAGCGGCGCCATTCGACCAGGCGACAGGTGGTTATCATGGCGGCGAGAAAAGTGTT
+ACCCAGCAGGTGGATTCCGCACGCACGATGGTAATTGGCCATACGGGAGCGCAAATTTTT
+AATAGCATCACCAGCAATGCGGTGCCGGAACCGGATGGCTCGGACTCCGAAAAGAATCTG
+TTTGTCATGCTCGATACGGCAATTGCCGCGCTCAAGACCCCGGTGGAAGGCAATGACGTG
+GAAAAAGAAAAAGCCGCTGCCGCCATTGATAAAACCAATCGCGGCTTAAAAAATTCGCTT
+AATAACGTCCTGACCGTTCGTGCGGAACTGGGAACGCAACTGAGCGAACTCAGTACGCTG
+GATTCACTGGGAAGCGACCGTGCGCTGGGACAGAAGCTACAGATGAGCAACCTGGTAGAT
+GTGGACTGGAACTCGGTCATTTCCTCCTACGTCATGCAACAGGCGGCATTACAGGCGTCC
+TATAAAACGTTTACCGACATGCAGGGAATGTCGCTTTTCCAGTTGAACCGGATGTCCAGC
+TTGATTAATCACGCCATGAGCGGACTTAACGCCGCGCAGGCCGCGTTAAATACGGTCAGT
+AATAACATCAACAATTATAACGTTGCGGGTTATACCCGGCAGACAACTATTCTGGCGCAG
+GCAAACAGTACGTTAGGGGCTGGCGGCTGGATAGGTAATGGCGTTTACGTTTCAGGCGTA
+CAGCGCGAATATGATGCGTTTATCACTAATCAGCTACGCGGCGCGCAAAACCAGAGCAGC
+GGCTTAACCACGCGCTATGAACAAATGTCGAAAATCGACAACCTGCTGGCCGATAAATCC
+AGCTCACTGTCTGGCTCGCTGCAGAGTTTTTTTACCAGCCTGCAAACGTTAGTCAGTAAT
+GCGGAAGATCCTGCGGCGCGTCAGGCGCTGATTGGTAAAGCGGAAGGGCTGGTAAACCAG
+TTCAAAACCACCGATCAGTATCTGCGCGATCAGGATAAACAGGTCAATATCGCGATTGGC
+TCCAGCGTGGCGCAAATCAACAATTACGCGAAGCAGATAGCTAACCTGAACGATCAAATC
+TCCCGTATGACGGGCGTAGGCGCGGGCGCATCGCCGAACGACCTGCTCGATCAACGTGAT
+CAGTTGGTTAGCGAGCTTAACAAGATCGTTGGCGTCGAGGTGAGTGTACAGGACGGCGGC
+ACCTATAACCTGACGATGGCCAATGGCTATACGCTGGTGCAGGGGTCGACGGCGCGTCAG
+TTGGCGGCGGTTCCCTCCAGCGCCGACCCGACGCGAACGACTGTCGCTTATGTCGATGAG
+GCCGCCGGTAACATCGAAATTCCGGAAAAGTTGCTGAACACCGGTTCGCTCGGCGGGCTA
+CTGACGTTCCGTTCTCAGGATCTGGATCAGACTCGTAATACGCTGGGCCAGTTGGCGTTG
+GCGTTTGCCGATGCGTTTAACGCGCAGCATACCAAAGGTTATGACGCCGACGGCAATAAA
+GGGAAAGACTTCTTTAGCATTGGCTCGCCGGTGGTATATAGCAACAGTAATAATGCCGAT
+AAAACGGTATCGCTAACCGCTAAGGTGGTCGACAGCACGAAGGTTCAGGCGACGGATTAT
+AAGATTGTTTTTGACGGTACAGACTGGCAGGTTACTCGCACTGCGGATAACACCACCTTC
+ACGGCAACAAAAGATGCTGACGGAAAACTGGAGATTGACGGTCTGAAAGTGACGGTAGGG
+ACTGGCGCACAGAAAAACGACAGTTTTCTTCTCAAGCCGGTCAGCAATGCTATCGTCGAC
+ATGAACGTTAAAGTGACAAATGAAGCCGAGATTGCGATGGCGTCTGAGTCAAAACTCGAT
+CCTGATGTGGATACCGGCGACAGCGATAACCGCAATGGTCAGGCATTGCTGGACTTACAA
+AACAGCAATGTAGTGGGCGGCAACAAAACCTTTAACGATGCTTACGCCACGTTGGTCAGC
+GATGTGGGTAACAAAACGTCAACGCTGAAAACCAGCAGCACCACGCAGGCGAATGTGGTT
+AAACAGCTTTATAAACAGCAACAGTCGGTTTCCGGCGTTAACCTCGACGAAGAGTACGGC
+AATTTGCAGCGTTATCAGCAGTATTATCTGGCGAATGCGCAAGTATTGCAGACCGCGAAT
+GCGCTGTTTGATGCGTTATTGAATATTCGCATGATCGGAGACGGTAAATTGCTGGCCAGC
+GCGGCCTGGGATGCGCAATCTCTGAACGAACTGAAAGCGAAAGCGGGCCAGGACCCGGCG
+GCGAATATCCGTCCTGTGGCCCGTCAGGTGGAAGGGATGTTTGTGCAGATGATGCTGAAA
+AGTATGCGCGAGGCTTTACCCAAAGATGGTTTATTCAGCAGCGATCAGACGCGTCTGTAT
+ACCAGCATGTATGACCAGCAGATCGCCCAGCAGATGACCGCCGGTAAGGGATTGGGGCTG
+GCGGATATGATGGTTAAACAGATGACGGGCGGGCAGACGATGCCTGCAGATGATGCGCCG
+CAAGTACCGCTTAAATTCTCCCTGGAGACGGTAAACAGCTATCAAAATCAGGCGCTGACC
+CAACTGGTGCGCAAAGCCATACCGAAAACGCCGGACAGCAGCGATGCGCCGCTCTCCGGC
+GACAGTAAAGACTTTCTGGCCCGGCTTTCGCTCCCGGCGAGGCTGGCCAGCGAACAAAGC
+GGGGTGCCGCATCATCTGATTCTGGCGCAGGCGGCGCTGGAGTCCGGCTGGGGGCAGCGG
+CAAATCCTGCGGGAGAATGGCGAACCCAGCTATAACGTATTTGGCGTGAAAGCGACCGCC
+AGTTGGAAAGGGCCGGTGACGGAAATCACCACCACTGAATACGAAAATGGCGAAGCGAAA
+AAAGTGAAAGCGAAATTCCGCGTCTATAGCTCGTATCTGGAGGCGTTATCGGATTATGTC
+GCGCTGTTAACGCGTAACCCACGCTACGCTGCCGTGACCACTGCCGCCACGGCAGAGCAG
+GGCGCAGTGGCTCTGCAAAACGCCGGATACGCCACTGACCCGAATTACGCGCGTAAATTG
+GCCAGCATGATTCAGCAGTTGAAAGCGATGAGTGAAAAGGTCAGCAAAACCTACAGCGCG
+AATCTCGACAATCTCTTTGTGTTTAAAGCTCTTGCAGGAATCGTTCTGGCACTGGTTGCC
+ACTCTGGCGCACGCCGAGCGTATCCGGGATCTGACCAGTGTCCAGGGAGTACGGGAAAAC
+TCGCTGATCGGCTACGGGCTGGTGGTCGGGCTGGACGGTACGGGCGACCAGACGACCCAG
+ACGCCATTTACCACCCAGACGCTGAATAACATGCTGTCACAACTGGGGATTACGGTCCCC
+ACCGGCACCAATATGCAGTTGAAAAACGTGGCGGCGGTGATGGTGACGGCGTCGTATCCG
+CCTTTTGCGCGACAGGGACAAACGATCGATGTCGTCGTTTCCTCAATGGGGAACGCTAAA
+AGTCTGCGTGGCGGGACGTTATTAATGACGCCGTTAAAAGGGGTGGACAGCCAGGTGTAT
+GCTCTGGCGCAGGGCAATATTCTGGTCGGCGGCGCGGGCGCTTCCGCAGGCGGCAGTAGC
+GTGCAGGTTAACCAGCTTAATGGCGGGCGCATCACTAATGGCGCGATTATCGAACGCGAG
+TTGCCGACTCAGTTCGGCGCTGGCAACACCATTAATCTGCAATTGAACGACGAAGATTTT
+ACGATGGCGCAGCAAATTACCGACGCCATCAACCGCGCCCGCGGTTACGGCAGCGCCACT
+GCGCTTGATGCGCGAACGGTACAGGTACGCGTGCCCAGCGGCAACAGCTCGCAGGTGCGT
+TTTCTGGCGGACATTCAAAATATGGAAGTCAACGTGACGCCGCAGGATGCAAAAGTCGTG
+ATCAACTCGCGTACCGGTTCGGTGGTCATGAATCGGGAAGTCACGCTGGATAGCTGCGCT
+GTGGCGCAGGGCAATTTGTCAGTGACAGTCAATCGCCAACTCAACGTCAACCAGCCGAAT
+ACGCCATTTGGCGGCGGGCAGACCGTGGTGACGCCACAGACTCAGATAGATTTGCGTCAG
+AGCGGCGGATCGCTACAGAGCGTGCGTTCCAGCGCCAATCTGAACAGCGTAGTGCGCGCG
+CTGAATGCGCTTGGCGCGACGCCGATGGATCTGATGTCGATTTTGCAGTCCATGCAGAGC
+GCGGGCTGTCTACGCGCCAAACTGGAAATCATCATGGCCCTGATGGTCGCGACGCTGACA
+GGATGCGCCTGGATACCCGCTAAACCGCTCGTGCAGGGGGCGACCACGGCGCAGCCGATA
+CCTGGCCCGGTACCGGTGGCGAATGGCTCCATATTTCAGTCTGCGCAGCCGATTAATTAT
+GGCTATCAGCCGCTTTTTGAAGATCGTCGACCGCGTAATATCGGCGATACGCTCACGATT
+GTGTTACAGGAAAACGTCAGCGCCAGTAAAAGCTCGTCGGCAAATGCCAGCCGCGACGGC
+AAAACCAGCTTTGGTTTTGATACGGTACCGCGTTATCTGCAGGGATTATTCGGTAATTCC
+CGCGCGGATATGGAGGCCTCCGGCGGCAACTCTTTTAATGGTAAAGGCGGCGCGAATGCC
+AGCAATACCTTTAGCGGCACGCTGACCGTGACCGTCGATCAGGTTCTGGCCAATGGCAAT
+TTACACGTCGTGGGGGAAAAACAGATCGCGATTAATCAGGGAACGGAATTCATCCGCTTC
+TCCGGCGTGGTAAATCCACGCACCATCAGCGGTAGCAACTCTGTTCCCTCGACACAGGTG
+GCGGATGCGCGGATTGAATATGTCGGGAACGGCTATATTAACGAAGCGCAAAATATGGGC
+TGGCTGCAACGTTTCTTCCTTAATTTGTCGCCGATGATGATCAGTTCATTATGGATCGCC
+AAAACCGGTCTGGACGCGCAGCAAACCAATATGGATGTGATTGCCAATAACCTGGCAAAC
+GTCAGCACCAATGGTTTTAAGCGTCAGCGCGCGGTATTTGAAGATCTGTTGTATCAGACC
+ATCCGCCAGCCGGGCGCGCAGTCGTCCGAGCAGACGACGCTGCCTTCCGGGCTGCAAATC
+GGTACCGGCGTGCGTCCGGTCGCCACGGAGCGCCTGCACAGTCAGGGGAACCTGTCGCAG
+ACCAACAACAGTAAAGATGTGGCGATTAAAGGGCAGGGCTTTTTCCAGGTCATGCTGCCG
+GACGGTACGTCTGCCTATACCCGCGACGGCTCTTTCCAGGTGGATCAGAATGGTCAACTG
+GTGACGGCGGGCGGTTTTCAGGTGCAGCCGGCAATCACCATTCCGGCCAACGCGTTAAGC
+ATCACGATTGGCCGCGACGGCGTGGTCAGCGTTACCCAGCAAGGGCAGGCCGCGCCGGTT
+CAGGTCGGGCAGCTTAACCTGACCACCTTTATGAACGACACCGGTCTGGAAAGCATCGGC
+GAGAACCTCTATATCGAAACGCAATCGTCCGGCGCGCCGAACGAAAGCACGCCGGGGCTC
+AACGGCGCGGGGTTGTTGTATCAAGGGTATGTCGAAACGTCGAACGTTAACGTGGCGGAA
+GAGCTGGTGAACATGATTCAGGTTCAACGCGCCTATGAAATTAACAGTAAAGCAGTATCG
+ACGACCGATCAGATGCTGCAGAAACTGACGCAACTCATGGATCACGCAATTTATACCGCC
+ATGGGGGCGGCCAGCCAGACGCTTAACCAGCAGGCGGTAACGGCCAGCAACCTGGCTAAT
+GCCTCAACGCCGGGCTTTCGCGCGCAGCTTAACGCGCTACGCGCGGTGCCCGTTGATGGC
+CTCTCTTTAGCGACGCGCACGTTGGTTACGGCGTCGACGCCGGGGGCGGATATGACCCAG
+GGTCAGTTGGACTACACTTCCCGCCCGCTGGATGTTGCGTTACAGCAGGACGGCTGGCTG
+GTGGTGCAAGCGGCGGATGGCGCTGAAGGATATACCCGTAACGGGAATATCCAGGTGGGC
+CCGACCGGGCAGTTAACCATTCAGGGACATCCGGTTATCGGCGAAGGCGGCCCGATTACC
+GTTCCGGAAGGGTCGGAAATCACCATTGCGGCAGACGGCACGATCTCCGCGCTCAATCCC
+GGCGACCCGCCAAACACGGTGGCGCCCGTTGGGCGGCTGAAGCTGGTCAAAGCGGAAGGC
+AATGAGGTGCAGCGGAGCGATGACGGTTTATTCCGCCTTACCGCCGAGGCACAGGCTGAA
+CGCGGGGCGGTACTGGCCGCCGACCCGTCAATTCGCATTATGTCGGGCGTGCTGGAGGGC
+AGTAACGTCAAGCCGGTTGAAGCCATGACCGACATGATCGCCAACGCACGTCGTTTTGAA
+ATGCAGATGAAGGTTATCACCAGCGTAGATGAGAACGAAGGGCGAGCTAACCAACTGCTG
+TCGATGAGTATGTCTTTTTCTCAAGCGGTTAGCGGCCTGAACGCTGCGGCCACCAACCTT
+GATGTTATCGGTAATAACATCGCCAACTCCGCCACCTATGGCTTTAAGTCCGGTACGGCA
+TCATTTGCCGATATGTTCGCCGGTTCCAAAGTGGGGTTGGGCGTAAAAGTGGCGGGGATT
+ACCCAGGATTTTACCGACGGTACGACAACGAACACCGGGCGCGGGCTGGATGTCGCGATT
+AGCCAGAACGGTTTTTTCCGCCTGGTAGACAGCAACGGTTCCGTGTTCTATAGCCGCAAC
+GGCCAGTTCAAACTGGACGAGAACCGTAACCTGGTCAATATGCAGGGGATGCAGTTGACC
+GGCTATCCGGCCACCGGTACGCCGCCGACCATTCAGCAGGGGGCGAATCCTGCGCCGATC
+ACCATTCCGAACACGCTGATGGCGGCGAAATCGACCACCACCGCGTCAATGCAGATCAAC
+CTGAACTCAACGGACCCTGTACCGTCTAAAACGCCCTTTAGCGTGAGTGATGCGGATTCG
+TATAACAAAAAAGGCACCGTCACCGTTTATGACAGCCAGGGTAATGCCCATGACATGAAC
+GTCTATTTTGTGAAAACCAAAGATAATGAATGGGCTGTGTACACCCATGACAGCAGCGAT
+CCTGCAGCCACTGCGCCAACAACGGCGTCCACTACGCTGAAATTCAATGAAAACGGGATT
+CTGGAGTCTGGCGGTACGGTGAACATCACCACCGGTACGATTAATGGCGCGACAGCGGCC
+ACCTTCTCCCTCAGCTTCCTTAACTCCATGCAGCAGAACACCGGGGCTAATAACATCGTC
+GCCACCAATCAAAACGGCTATAAGCCTGGCGACCTGGTGAGCTACCAGATTAACAATGAT
+GGCACCGTGGTTGGCAACTACTCCAACGAGCAGGAGCAGGTGCTGGGGCAGATTGTGCTG
+GCTAACTTCGCCAACAACGAAGGTCTGGCATCCCAGGGCGATAACGTCTGGGCGGCGACG
+CAGGCCTCCGGGGTAGCGCTGCTGGGGACTGCCGGTTCCGGCAACTTCGGTAAGCTGACG
+AACGGCGCGCTGGAAGCCTCTAACGTGGATTTGAGTAAAGAGCTGGTGAATATGATCGTC
+GCGCAGCGTAACTACCAGTCGAATGCGCAGACCATCAAAACCCAGGACCAGATCCTCAAT
+ACGCTGGTTAACCTGCGCATGTCTATTGCCGTAAATATGAATGACCCGACCAACACGGGC
+GTCAAAACGACGACCGGCAGCGGGTCGATGACCGGAAGCAACGCTGCCGATCTGCAAAGC
+AGTTTCCTGACCTTACTGGTCGCGCAATTGAAGAACCAGGACCCGACTAACCCATTACAA
+AATAATGAGTTAACGACACAGTTGGCGCAAATCAGTACCGTGAGCGGCATTGAAAAACTG
+AATACGACGCTGGGGGCTATTTCCGGGCAAATCGATAATAGTCAGTCCCTACAGGCGACC
+ACGCTGATTGGACATGGCGTTATGGTGCCTGGCACCACAATTCTGGCGGGTAAAGGCGCG
+GAAGAAGGGGCCGTGACGTCCACGACGCCGTTTGGCGTGGAATTGCAACAGCCTGCGGAC
+AAAGTGACGGCAACCATTACCGATAAAGATGGCCGGGTGGTACGGACGCTGGAGATCGGT
+GAGTTGCGAGCCGGGGTACACACCTTTACCTGGGATGGTAAGCAAACGGACGGAACAACG
+GTACCGAATGGTTCTTACAACATTGCGATTACCGCCAGCAATGGCGGGACGCAACTGGTG
+GCGCAGCCGCTGCAATTCGCTCTGGTACAGGGCGTGACGAAGGGCAGTAACGGCAACCTG
+TTGGATCTGGGTACCTACGGCACCACCACACTCGACGAAGTTCGGCAAATAATCATGCAA
+ATACAGAGCTTCTATCACTCAGCTTCACTAAAAACCCAGGAGGCTTTTAAAAGCCTACAA
+AAAACCTTATACAACGGAATGCAGATTCTCTCAGGCCAGGGCAAAGCGCCGGCTAAAGCG
+CCCGACGCTCGCCCGGAAATTATTGTCCTGCGAGAACCTGGCGCGACATGGGGGAATTAT
+CTACAGCATCAGAAGACGTCTAACCACTCGCTGCATAACCTCTATAACTTACAGCGCGAT
+CTTCTTACCGTCGCGGCAACCGTTCTGGGTAAACAAGACCCGGTTCTAACGTCAATGGCA
+AACCAAATGGAGTTAGCCAAAGTTAAAGCGGACCGGCCAGCAACAAAACAAGAAGAAGCT
+GCGGCAAAAGCATTGAAGAAAAATCTTATCGAACTTATTGCAGCACGCACTCAGCAGCAA
+AATGGCTTACCTGCAAAAGAAGCTCATCGCTTTGCGGCAGTAGCGTTTAGAGATGCTCAG
+GTCAAGCAGCTCAATAACCAGCCCTGGCAAACCATAAAAAATACACTCACGCATAACGGG
+CATCACTATACCAACACGCAGCTCCCTGCCGCAGAGATGAAAATCGGCGCAAAAGATATC
+TTTCCCAGTGCTTATGAGGGAAAGGGCGTATGCAGTTGGGATACCAAGAATATTCATCAC
+GCCAATAATTTGTGGATGTCCACGGTGAGTGTGCATGAGGACGGTAAAGATAAAACGCTT
+TTTTGCGGGATACGTCATGGTGTGCTTTCCCCCTATCATGAAAAAGATCCGCTTCTGCGT
+CAGGCCGGCGCTGAAAACAAAGCCAAAGAAGTATTAGCTGCGGCACTTTTTAGTAAACCT
+GAGTTGCTTAACAGAGCCTTAGAGGGCGAAGCGGTAAGCCTGAAACTGGTATCCGTCGGG
+TTACTCACCGCGTCGAATATTTTCGGCAAAGAGGGAACTATGGTCGAGGATCAAATGCGC
+GCATGGCAATCGTTGACCCAGCCGGGAAAAATGATTCATTTAAAAATCCGCAATAAAGAT
+GGCGATCTACAGACGGTAAAAATAAAACCGGACGTCGCCGCATTTAATGTGGGTGTTAAT
+GAGCTGGCGCTCAAGCTCGGCTTTGGCCTTAAAGCATCAGATAGCTATAATGCCGAAGCG
+CTACATCAGTTATTAGGCAATGATTTACGCCCTGAAGCCAGACCAGGTGGCTGGGTTGGC
+GAATGGCTGGCGCAATACCCGGATAATTATGAGGTCGTCAATACATTAGCGCGCCAGATT
+AAGGATATCTGGAAAAATAACCAACATCATAAAGATGGCGGCGAACCCTATAAACTCGCA
+CAACGCCTTGCCATGTTAGCCCATGAAATTGACGCGGTGCCCGCCTGGAATTGTAAAAGC
+GGCAAAGATCGTACAGGGATGATGGATTCAGAAATCAAGCGAGAGCTCATTTCTTTCCAT
+CAGACCCATATGTTAAGTGCGCCTGGTAGTCTTCCGGATAGCGGTGGACAGAAAATTTTC
+CAAAAAGTATTACTGAATAGCGGTAACCTGGAGATTCAGAAACAAAATACGGGCGGGGCG
+GGAAACAAAGTAATGAAAAATTTATCGCCAGAGGTGCTCAATCTTTCCTATCAAAAACGA
+GTTGGGGATGAAAATATTTGGCAGTCAGTAAAAGGTATTTCTTCATTAATCACATCTATG
+AAAAAGTATCTTGCTTTCGCCGTTACGCTGCTGGGTATGGGTAAAGTCATCGCCTGTACT
+ACCCTTTTGGTAGGCAATCAGGCTTCGGCTGACGGCTCCTTTATTATCGCGCGCAACGAG
+GATGGCTCGGCAAATAACGCCAAGCATAAGGTTATTCATCCCGTCGCGTTTCATCAACAA
+GGCGAGTATAAAGCACATCGCAACAATTTTAGCTGGCCGCTTCCGGAGACAGCGATGCGC
+TATACGGCGATTCATGACTTTGATACTAACGATAACGCCATGGGTGAAGCCGGTTTCAAT
+TCGGCGGGCGTCGGAATGAGCGCAACGGAAACCATTTACAACGGCAGAGCGGCGCTGGCT
+GCCGATCCTTACGTGACAAAAACGGGAATCACGGAAGACGCCATTGAGTCCGTGATCCTG
+CCAGTGGCGCAATCGGCGCGTCAGGGCGCCAAATTACTGGGAGATATTATTGAACAAAAA
+GGCGCGGGCGAAGGTTTCGGCGTCGCGTTTATTGATAGCAAAGAGATATGGTATCTGGAG
+ACGGGAAGCGGACATCAATGGCTGGCAGTACGACTTCCGGCAGATAGCTATTTCGTTTCC
+GCCAATCAGGGACGTTTACGCCATTACGATCCGAATGATAACGCGAATTATATGGCGTCA
+CCAACGTTAGTAAGCTTTGCGAAAAAGCAGGGATTATATGATCCGGCCCGCGGCGAATTC
+GACTTTCATCAAGCCTATTCGCAGGATAACAAAAACGATACCACCTATAATTATCCGCGC
+GTCTGGACGCTACAACACCAGTTTAATCCGCATCTGGATACGGTCGTTAGCGAAGGGGAA
+ACATTTTCTGTTTTTTTAACGCCAATAACGAAGATCAGCGTGGCGGCAGTAAAAAACGCG
+TTACGCAATCACTATCAGGGAACGTCGCACGACCCTTATGCCAGTCATAATCCACAAGAA
+CCATGGCGACCTATATCCGTTTTTCGTACCCAGGAGTCACATATTTTACAGGTCAGACCG
+AAATTACCGCAGGCTATCGGCAACGTAGAATACATCGCCTATGGAATGCCATCTCTTAGC
+GTCTATCTCCCCTATTACCAGGGGATGCGTCATTATCAACCCGGAGATGATAAAGGAACC
+GATCGGGCGAGCAACGACTCTACCTACTGGACATTCCGCACGCTGCAAACACTGGTTATG
+CAAGACTACAATACGTTTGCGCCAGATGTGCAACATGCCTGGAAAACATTTGAACAGCAA
+ACAGCTAAGCAACAGTATAAGATGGAGCAGAGCTATCTGAGATTATATGCGTCGCATCCG
+AAAGAAGCACAACGCTTACTGCAAAATTTTGAAGATAAAACGATGCAAAATGCGCAGACG
+CTCGCCCGTCGCCTGACCAATAATATTATTACGACAATGACTTACCGCACAGATATGAAA
+TATCACTTTTCAAGTACGCAGCCAATGGTTAAGTTATCAATGACGCTGCGCCTGACAATT
+TCTTTTATCGCCATACTTATCCTCGCCTGTACCGGCATTAGCTGGACGCTCTATAACGCG
+CTGAGCAAAGAATTAACGTATCGGGATGATATGACGCTAATAAATCGGGCGGCGCAAATG
+CAGCAACTGTTACTGGATGGCGCCAGGCCGGAAAATCTGCCGCTCTATTTCAATCGGATG
+GTGGATACGAAGCAGGATATCTTATTGATCCACTCAGCAACAGGCCATAATGTTGCGATT
+AATCATAGCGGCATCCCCGACCAACGCTTTAACGAGATTCCGCTGGCTAAAAACATCACC
+CGCGAAACCTTATTTCGCCAGGCGGTACAAGGCACGGAGCTGACCGCGGTACGAGTAAAC
+GCCAGAAGCGGCGATAACCCGCTGACCCTTACTATTGCCAGGCTGGCGACGGAAAGGCGG
+CAAATGCTGGCGCAATATCGCCGCAACAGTTTGCTGATTAGCCTTATCGCGATCCTCGTC
+TGTTCGGCGCTCAGTCCATTAGTCATCAGAAACGGGCTGCGGGCCATTACGTCGCTCAGC
+CGACTCACCGCGGCGACAGATAGCGGCACACTTCGCCAGCCGCTGGCGGAACAGGCGTTA
+CCCGTCGAGCTCAGGCCGCTTGGGCAAGCGCTAAATACCATGCGCCAGAAGCTTTCCGAC
+GATTTTGAACGCCTGAACCAATTTGCCGACGATCTGGCGCATGAGCTGCGCACGCCGGTT
+AATATTTTACTGGGGAAGAATCAGGTTATGCTGAGTCAGGAACGCAGCGCCGAAGAGTAT
+CAACAAGCCCTTGTCGATAATATTGAAGAGCTGGAGGGACTGTCGCGACTGACAGAAAAT
+ATTCTCTTTCTGGCACGCGCGGAGCACCAGAATATAGCGGTAAAAAAACAGCCTGTTTCG
+CTCAATGCGCTGGTCGAAAATATGCTGGATTATCTTAGCCCCCTTGCCGAAGAGAAGCAC
+ATCTGTTTTATAAATCAATGTCAGGGAACGGTATGGGCTGACGAAATATTATTACAAAGA
+GTGCTCTCAAACCTGCTGACGAATGCCATCCGTTATTCTGATGAAAACGCCGTGATACGT
+ATTGAAAGCGCTTATGATGATAACGTTGCAGAAATTCGGGTCGCTAATCCGGGCAGCCCC
+ACCGCCGATGCGGATAAGCTTTTCCGGCGTTTTTGGCGAGGAGATAATGCCCGCTACACT
+GCCGGTTTCGGCCTGGGGTTATCGTTAGTTAACGCGATTGCCCTATTGCACGGTGGCTCG
+GCATCTTACCGCTATGCCGATGAACATAATATCTTTTCGGTTCGTCTGCCTGATAGCGGT
+GATAGCATGTCATCTTGTTGGAGATTTACGGATTCGCTAACAAGCCTATGGCATACTGCG
+TTGATGAAGATTTTATTGATTGAAGATAACCAGAAAACCATTGAGTGGGTACGTCAGGGA
+CTCACGGAGGCAGGCTATGTGGTTGATTATGCCTGTGATGGACGAGACGGATTACACCTA
+GCCCTTCAGGAACATTATTCATTGATTATTCTTGATATTATGCTGCCGGGGCTTGATGGA
+TGGCAGGTTTTACGCGCGTTGCGCACTGCATATCAGCCCCCTGTTATTTGCCTGACGGCG
+CGCGACTCGGTTGAGGATCGCGTCAAAGGTCTTGAGGCGGGCGCTAATGATTACCTTGTT
+AAGCCTTTTTCCTTCGCCGAACTGCTGGCCCGGGTGAGAGCTCAACTCAGACAGCATGTC
+CCGGTCTTTACCCGACTGACGATCAATGGTCTGGACATGGATGCCACAAAGCAATCGGTG
+TTACGAAATGGCAAACCGATTTCCCTGACCCGCAAAGAATTCCTGCTCCTCTGGTTACTG
+GCGTCCCGGGCAGGGGAAATCGTGCCCCGAACCGCGATCGCCAGCGAAGTTTGGGGAATT
+AACTTTGATAGTGAAACCAACACCGTTGATGTCGCGATTCGTCGGCTGCGCGCCAAAGTA
+GACGATCCATTTGAAAAGAAGCTCATTATGACCGTCCAGGGGATGGGTTATCGATTACAG
+GCGGAAACGTCGCAGAATGGTATGAAACGATATATACTGGCTACCGCGATAGCGTCTCTT
+GTTGCAGCCCCGGCAATGGCGCTGGCCGCTGGCAGCAATATTCTCAGCGTACATATTCTC
+GATCAGCAAACAGGCAAACCAGCGCCCGGCGTGGAGGTGGTACTGGAGCAGAAAAAGGAT
+AACGGATGGACGCAATTAAACACCGGGCATACCGACCAGGATGGACGAATTAAAGCACTG
+TGGCCCGAAAAAGCTGCCGCGCCGGGGGATTATCGCGTTATTTTTAAAACCGGCCAGTAT
+TTTGAAAGTAAAAAACTGGACACGTTTTTCCCGGAGATTCCCGTCGAGTTTCATATCAGC
+AAAACGAATGAGCACTATCATGTGCCGCTGTTATTAAGTCAGTATGGTTATTCAACCTAT
+CGCGGGAGCATGCAAGTAGATGAACAACGTCTGCGTTTTCGCGATGCGATGGCAAGTCTG
+GCGGCAGCGGTCAACATCGTAACCACGGCGGGTCACGCCGGACGCTGCGGTATCACCGCA
+ACAGCGGTTTGCTCAGTCACTGATACGCCGCCCTCCGTGATGGTATGTATTAATGCCAAT
+AGCGCCATGAACCCCGTTTTTCAGGGCAACGGCAGGCTGTGCATTAATGTACTTAACCAT
+GAGCAGGAGCTGATGGCGCGCCACTTTGCCGGTATGACGGGGATGGCGATGGAGGAGCGT
+TTTCACCAGCCATGTTGGCAAAACGGGCCGCTGGGCCAGCCGGTACTTAACGGCGCGCTG
+GCCAGTCTTGAAGGCGAGATCAGCGAGGTACAAACCATTGGCACGCATCTGGTGTATCTG
+GTGGCGATCAAAAATATTATTCTTAGCCAGGAGGGGCATGGCCTGATTTATTTCAAACGC
+CGTTTTCATCCGGTCAGACTTGAGATGGAAGCGCCTGTTATGGGACGCACACCGGATTAC
+AAAGCCGCCTTTGGCTGCGCTCTGGGCGCTAACCCAGCCTTCTACGGCCAGTTTGAGCAG
+AACGCCCGTAACTGGTACACCCGTATTCAGGAGACCGGCCTGTACTTTAACCATGCAATC
+GTCAACCCGCCCATTGACCGCCACAAACCTGCCGACGAAGTGAAAGACGTCTATATCAAG
+CTGGAGAAAGAGACGGACGCCGGGATTATTGTCAGCGGGGCGAAAGTTGTCGCCACTAAC
+TCCGCCCTGACTCACTACAACATGATTGGTTTCGGCTCAGCCCAGGTGATGGGCGAAAAC
+CCGGATTTTGCTCTGATGTTTGTCGCGCCAATGGATGCCGAAGGCGTAAAACTTATTTCG
+CGCGCCTCGTATGAAATGGTCGCGGGCGCGACGGGCTCGCCGTTTGATTATCCCCTCTCC
+AGCCGTTTTGATGAAAACGATGCCATTCTGGTGATGGACAAGGTGCTGATCCCGTGGGAA
+AACGTATTAATTTACCGTGATTTCGATCGTTGTCGTCGCTGGACGATGGAAGGCGGCTTT
+GCCCGTATGTATCCACTGCAAGCCTGTGTTCGTCTGGCGGTAAAACTTGATTTCATTACC
+GCGCTGCTGAAAAAATCGCTCGAATGTACGGGTACCGTAGAGTTCCGGGGCGTGCAGGCC
+GATCTCGGCGAAGTCGTGGCCTGGCGCAATATGTTCTGGGCATTGAGCGATTCTATGTGT
+TCTGAAGCAACCCCGTGGGTAAACGGCGCCTGGCTACCGGACCACGCCGCGCTGCAAACC
+TATCGTGTGATGGCCCCAATGGCCTACGCGAAAATTAAAAATATTATTGAACGTAACGTT
+ACCAGCGGCCTGATTTACCTGCCTTCCAGCGCCCGCGATCTGAATAATCCGCAAATCGAC
+CAGTACCTGGCGAAATACGTACGCGGCTCTAACGGAATGGACCATGTTGAACGTATCAAA
+ATTCTTAAATTGATGTGGGATGCCATCGGCAGCGAGTTTGGCGGTCGCCATGAGCTGTAC
+GAGATTAACTACTCGGGCAGCCAGGATGAAATTCGTCTGCAGTGTCTGCGTCAGGCCCAG
+AGCTCCGGCAATATGGATAAGATGATGGCAATGGTCGATCGCTGCCTCTCCGAATACGAT
+CAGAATGGCTGGACGGTTTCGCATTTGCACAATAACGACGACATCAATCAACTGGATAAG
+CTGCTGAAAATGCATGATTCATTAACCATCGCCTTGCTTCAGGCGCGCGAAGCGGCAATG
+ACCTATTTCCGCCCCATCGTTAAAAGCCACAATCTGACCGACCAGCAATGGCGCATTGTG
+CGAATCCTGGCCGATAGCCCCTCTATGGATTTTCACGAGCTGGCCTTTCGTACCTGTATT
+TTGCGTCCAAGTCTGACCGGAATATTGACGCGCATGGAGCGAGACGGACTGGTGTTGCGA
+CTCAAGCCGGTTAACGATCAGCGTAAGTTATATGTCATGTTGACGGAGCAGGGACAAACG
+TTGTACGCCCGTGCCCGGAGCGAGGTAGAAGAGGCTTATCGAAAAATTGAGGCCGATTTC
+ACGCCCGAAAAAACACAGCAATTGATGCTGCTGCTGGACGATCTTATTGCTCTGGGGCGC
+CAGCATCCTGATAGCGAAGCGGAAGCAATGAAGGGTACTGTTTTCGCCGTTGCGTTAAAC
+CATCGCAGCCAGCTTGATGCCTGGCAAGAGGCTTTCTCTCAGCCTCCCTATAATGCGCCG
+CCTAAAACCGCAGTGTGGTTCATCAAGCCGCGTAATACGGTGATTCGTCACGGCGAACCC
+ATTCCTTATCCGCAGGGAGAAAAGGTACTGAGCGGCGCGACAGTGGCGCTCATTGTGGGG
+AAAACCGCCAGCCGGATACGCCCTGAAGCGGCGGCGGACTATATCGCCGGGTATGCGCTG
+GCTAACGAGGTCAGCCTGCCGGAAGAGAGCTTTTATCGCCCGGCGATTAAAGCGAAATGT
+CGCGATGGCTTTTGCCCGCTGGGTGAAATGGCGCCGCTGAGTGATGTGGATAATCTCACC
+ATTATCACTGAAATCAACGGACGAGAAGCGGACCACTGGAATACTGCCGATTTACAGCGT
+AGCGCCGCACAACTGCTTAGCGCGTTAAGTGAGTTCGCTACACTTAACCCTGGCGATGCG
+ATCTTACTTGGTACGCCGCAGAATCGCGTTGCGCTGCGTCCCGGCGATCGGGTGCGTATT
+CTGGCGAAAGGTTTACCCGCGCTGGAAAATCCGGTTGTCGCAGAAGATGAATTCGCCCGC
+CACCAGACGTTTACGTGGCCGCTGTCAGCGACGGGAACGTTATTTGCGCTGGGGTTGAAC
+TACGCCGATCACGCCAGCGAGCTGGCATTTACGCCGCCGAAAGAGCCGCTGGTATTTATC
+AAAGCGCCAAACACCTTTACCGAACATCACCAAACGTCGGTGCGCCCGAACAACGTCGAA
+TATATGCACTACGAAGCCGAGCTGGTCGTGGTGATTGGCAAAACGGCGCGTAAGGTGAGC
+GAAGCCGAAGCCATGGAGTATGTGGCCGGTTACACCGTCTGTAACGACTACGCGATCCGC
+GACTATCTGGAAAACTACTACCGTCCGAATCTGCGGGTAAAAAGCCGCGACGGCCTGACG
+CCGATAGGCCCGTGGATTGTGGATAAAGAGGCGGTTTCTGATCCGCACAACCTGACGTTA
+CGCACCTTTGTCAACGGTGAGCTGCGGCAGGAAGGGACGACCGCCGATCTGATCTTCAGC
+ATCCCGTTCCTGATTTCTTATCTGAGCGAATTTATGACGTTGCAACCGGGCGACATGATT
+GCCACCGGTACGCCGAAAGGGCTGTCCGATGTGGTGCCGGGGGATGAAGTTGTCGTTGAA
+GTAGAAGGCGTGGGTCGCCTGGTTAACCGAATCGTCAGTGAGGAGAGCGCAAAAATGAAG
+AAAATAAATCATTGGATTAACGGCAAAAACGTTGCAGGTAACGACTACTTCCAGACCACT
+AACCCGGCGACCGGTGATGTGCTGGCGGAAGTAGCCTCCGGCGGTGAAGCAGAAGTGAAC
+CAGGCTGTCGCGGCGGCAAAAGAGGCGTTCCCGAAATGGGCCAACCTGCCGATGAAAGAG
+CGCGCGCGCCTGATGCGCCGCCTTGGCGACCTGATTGACCAGCATGTGCCGGAAATCGCG
+GCGATGGAAACCGCCGACACCGGCCTGCCTATTCACCAGACTAAAACGTGCGTGCTGATC
+CCGCGCGCCTCGCATAACTTCGAATTCTTCGCCGAAGTGTGCCAGCAGATGAACGGCAAG
+ACCTATCCGGTTGACGATAAAATGCTCAATTATACGCTGGTGCAGCCCGTCGGCGTCTGC
+GCGCTGGTGTCGCCGTGGAACGTGCCGTTTATGACCGCGACTTGGAAAGTTGCGCCGTGC
+CTGGCGCTGGGTAACACCGCGGTGCTCAAAATGTCCGAGCTGTCGCCGCTGACTGCCGAC
+AGGCTGGGCGAGCTGGCACTGGAGGCAGGAATTCCGGCAGGCGTGCTGAACGTGGTGCAG
+GGCTACGGCGCGACGGCGGGCGATGCGCTGGTACGCCACCATGACGTGCGTGCGGTGTCG
+TTTACCGGCGGTACCGCCACCGGTCGCAATATCATGAAAAATGCCGGGCTGAAAAAATAC
+TCGATGGAGCTGGGCGGCAAATCGCCGGTGCTGATTTTTGAAGACGCCGACATTGAGCGC
+GCGCTGGACGCCGCGCTGTTCACCATCTTCTCGATCAACGGCGAACGCTGCACCGCTGGG
+TCGCGCATCTTTATCCAGCAGAGCATTTACCCTGAGTTCGTGAAGCGCTTTGCCGAACGC
+GCGAATCGCCTGCGTGTCGGCGATCCGACCGACCCGAACACCCAGGTCGGCGCGCTGATT
+AGCCAACAGCACTGGGAGAAAGTCTCCGGTTATATCCGCCTCGGCATTGAAGAGGGGGCA
+ACGCTGCTGGCGGGCGGTGCGGAAAAACCCACTGACCTGCCTGCGCATCTGAAAGGCGGT
+AACTTCCTGCGCCCAACCGTGCTGGCCGATGTCGACAACCGTATGCGCGTTGCGCAGGAA
+GAGATCTTTGGGCCGGTCGCCTGCCTGCTGCCATTCAAAGACGAAGCGGAAGGGTTACGT
+TTGGCGAACGATGTGGAATACGGTCTGGCCTCTTATATCTGGACCCAGGACGTGAGCAAA
+GTGTTGCGCCTGGCGCGTGGGATTGAAGCCGGCATGGTCTTCGTCAACACCCAGAACGTC
+CGCGACCTGCGCCAGCCGTTCGGCGGCGTGAAAGCCTCCGGTACCGGGCGCGAAGGCGGC
+GAATATAGCTTCGAAGTGTTTGCGGAAATGAAAAACGTCTGCATCTCAATGGGCGACCAT
+CCTATCCCAAAATGGGGAGTTATGGGCAAGTTAGCGTTAGCAGCAAAAATTACCCACGTG
+CCGTCGATGTATCTTTCTGAACTGCCAGGAAAAAATCACGGTTGTCGTCAGGCAGCCATT
+GATGGGCATATTGAAATTGGCAAGCGTTGCCGCGAAATGGGCGTTGACACCATTATCGTA
+TTCGACACCCACTGGCTGGTGAATAGCGCTTACCACATTAATTGTGCCGACCATTTCCAG
+GGCGTCTATACCAGCAACGAATTGCCGCACTTTATTCGCGACATGACCTATGACTATGAC
+GGTAATCCGGCGCTCGGCCATCTGATCGCCGACGAGGCGGTCAAACTGGGCGTGCGCGCC
+AAAGCGCACAACATCCCGAGCCTGAAGCTGGAGTATGGCACGCTGGTGCCGATGCGCTAC
+ATGAACAGCGACAAGCACTTCAAAGTGGTCTCCATCTCGGCGTTCTGCACTGTGCATGAT
+TTTGCCGACAGCCGCAAACTGGGCGAAGCCATTCTCAAGGCGATTGAGAAATATGACGGT
+ACCGTAGCGGTATTCGCCAGTGGTTCTCTGTCGCACCGTTTTATTGACGACCAACGGGCG
+GAAGAGGGGATGAACAGCTACACCCGCGAGTTCGATCATCAAATGGACGAGCGCGTGGTC
+AAGCTGTGGCGCGAAGGCAAATTCAAGGAGTTTTGCACCATGTTGCCGGAGTACGCCGAC
+TACTGCTACGGCGAAGGCAACATGCACGACACGGTCATGCTACTGGGAATGCTGGGGTGG
+GACAAATACGACGGCAAGGTGGAGTTCATCACCGACCTGTTCGCCAGCTCCGGTACCGGC
+CAGGTAAACGCTGTTTTCCCGCTGCCTGCGATGCCGCACTTTATTGCTGAATGTACTGAA
+AATATTCGCGAGCAGGCTGATTTACCAAGCCTGTTCAGCAAGGTAAACGAGGCGCTGGCC
+GCCACCGGGATTTTCCCCATCGGCGGTATCCGCAGTCGCGCCCACTGGCTGGATACCTGG
+CAGATGGCTGACGGTAAGCATGATTACGCGTTTGTGCATATGACGCTGAAAATCGGCGCC
+GGGCGCAGCCTGGAGAGCCGTCAGGAAGTCGGCGAAATGCTGTTTGGGCTGATTAAAGCC
+CACTTCGCCGACCTGATGGAGAACCGCTATCTGGCGCTGTCGTTTGAGATTGCCGAGTTA
+CATCCAACGCTCAATTACAAACAAAACAACGTACACGCGTTATTTAAAATGCTCGATAAA
+CAGACCCATACCCTGATCGCTCAGCGACTTAATCAGGCTGAAAAACAGCGTGAACAGATT
+CGCGCAGTGTCGCTGGATTATCCCAACATCACTATTGAAGATGCCTATGCCGTACAGCGT
+GAATGGGTCAATATCAAGATTGCCGAAGGGCGCACGCTCAAAGGCCACAAAATCGGCCTG
+ACCTCAAAAGCGATGCAGGCCAGCTCGCAAATCAGCGAACCGGATTACGGCGCGCTGCTT
+GACGATATGTTCTTCCATGACGGCGGAGATATCCCCACCGACCGTTTTATCGTCCCGCGT
+ATTGAAGTGGAGCTGGCGTTCGTGCTGGCGAAACCGCTGCGCGGCCCTCACTGCACGCTG
+TTCGACGTCTACAACGCCACGGATTATGTGATTCCGGCGCTGGAACTGATTGACGCCCGC
+AGCCACAACATCGACCCGGAAACCCAGCGCCCGCGCAAAGTGTTCGACACCATTTCCGAC
+AACGCCGCCAACGCCGGGGTGATCCTCGGTGGTCGCCCCATCAAACCAGACGAGCTGGAT
+CTGCGCTGGATCTCCGCGCTGCTCTATCGCAACGGCGTGATCGAAGAAACCGGCGTCGCC
+GCAGGCGTGCTGAATCATCCGGCCAACGGCGTGGCGTGGCTGGCGAACAAGCTTGCCCCC
+TACGATGTCCAGCTTGAAGCCGGGCAGATCATCCTCGGCGGCTCGTTCACCCGCCCGGTG
+CCGGCGCGCAAGGGCGACACCTTCCATGTCGATTACGGCAACATGGGCGCGATCAGTTGC
+CGGTTTGTGATGAAAAATGCTTTCAAAGACGCGTTAAAAGCGGGGCGCCCGCAAATCGGT
+TTGTGGCTGGGGCTTGCCAACAGTTACAGCGCTGAACTGTTAGCGGGCGCCGGCTTCGAC
+TGGCTACTGATTGACGGTGAACACGCGCCAAACAACGTGCAGACGGTGTTGACCCAGTTG
+CAGGCGATTGCGCCTTATCCCAGCCAGCCGGTGGTGCGTCCGTCATGGAACGATCCGGTA
+CAGATTAAGCAACTGCTCGACGTCGGCGCGCAAACGCTGCTGATACCGATGGTGCAGAAT
+GCCGATGAAGCGCGAAACGCCGTGGCGGCTACGCGTTATCCGCCTGCCGGTATTCGCGGC
+GTGGGCAGCGCGCTGGCGCGGGCATCGCGCTGGAATCGCATTCCGGACTATCTCCACCAG
+GCCAACGACGCCATGTGCGTACTGGTGCAGATTGAAACGCGTGAGGCGATGAGCAATCTG
+GCGTCAATTCTCGACGTGGATGGCATTGACGGCGTGTTTATTGGCCCGGCGGATCTCAGC
+GCCGATATGGGCTTTGCCGGCAATCCGCAGCACCCGGAAGTGCAGGCGGCGATTGAGAAC
+GCCATCGTGCAGATACGCGCGGCGGGGAAAGCGCCGGGGATTCTGATGGCCAATGAAGCA
+CTGGCGAAACGTTATCTGGAACTGGGGGCGCTATTTGTCGCCGTCGGCGTTGACACCACG
+CTGCTGGCGCGCGGAGCGGAGGCGCTGGCGGCGCGCTTTGGCGCAGAAAAAAAACTGTCC
+GGTGCGTCCGGCGTCTATATGAGCGACACATCATCTGCACTTCCGGAAAGCCCCGAGTCT
+GTCGGTTCGCACAACGCGCTCAGCACGGGTCAACAAACCGTCATAAATAAACTGTTCCGC
+CGACTGATCGTATTTTTATTCGTGTTGTTTATCTTCTCGTTTTTAGACCGTATCAACATC
+GGTTTTGCCGGGTTGACGATGGGGCAGGATCTGGGGTTAAGCGCCACCATGTTTGGTCTT
+GCCACGACGCTGTTTTACGCCACCTACGTCATTTTCGGCATTCCCAGCAACGTGATGTTG
+AGCATCGTCGGCGCCCGCCGCTGGATTGCGACCATTATGGTGCTATGGGGCATTGCATCT
+ACCGCCACGATGTTCGCGGTGGGACCGAAAAGCCTGTATGTGCTGCGAATGCTGGTGGGC
+ATTACCGAAGCGGGCTTTTTGCCAGGAATATTGCTCTATTTAACCTACTGGTTCCCGGCA
+TTTTTCCGCGCCCGCGCCAACGCATTATTTATGATTGCCATGCCGGCCACTACCGCGTTG
+GGGTCAATTGTCTCCGGCTATATTTTATCGCTGGACGGCATATTCAATCTGCATGGATGG
+CAGTGGTTATTCCTGTTGGAAGGATTTCCGTCAGTTTTGTTAGGCATTATGGTCTGGTTT
+TACCTGGATGATACCCCGGCAAAAGCCAAATGGCTGACGGCAGAGGATAAAAAATGTTTG
+CAGGAGATGATGGATAATGATCGCCTGACGCTGGTTCAGCCTGAGGGGGCCATCAGCCAT
+AACGCCATGCAGCAGCGTAGCCTGTGGCGCGAAGTATTCACGCCAATTGTACTGATGTAT
+ACGCTGGCCTATTTTTGCCTTACCAATACGCTTAGCGCCATTAGTATCTGGACGCCGCAA
+ATCCTGAAAAGTTTTAATGAAGGCAGCAGCAATATCACCATCGGCCTGCTGGCGGCGATC
+CCGCAGATTTGTACTGTTCTGGGCATGATTTACTGGAGCCGCCATTCGGACAAACATCAG
+GAGCGTAAACACCACACTGCGTTACCGTTCCTGTTTGCCGCCGCGGGCTGGCTGCTGGCG
+TCGGCGACCGACCGTAACCTGATCCAGCTCCTGGGGATCGTGATGGCATCCACGGGTTCC
+TTTAGCGCGATGGCGATCTTCTGGACCACGCCGGATCAGTCGATCAGTTTACGCGCCAGG
+GCGATAGGCATTGCGGTCATCAATGCCACCGGCAATATTGGCTCCGCGCTCAGCCCGGTT
+ATGATTGGCTGGCTAAAAGATATCACTGGTAGCTTCAATAGCGGACTCTGGTTTGTCGCT
+TCTCTGTTAGTCGTCGGCGCCGCCATTATCTGGCTCATTCCCATGAAAGCATCGCGTCCG
+CGCGCCACCCCTATGTGCCAACGTGCGATCGCCAATATTGATATCAGCAAAGAGTATGAC
+GAAAGCATGGGCAGTAACGATGTGCATTATCAGTCGTTTGCTCGTATGGCGGATTTCTTT
+GGTCGTGATATGCAGGCGCATCGCCACGACCAGTTTTTTCAAATGCACTTTCTTGATACC
+GGGCAGATTGAGCTACAGCTCGACGATCATCGCTATTCGGTGCAGGCGCCGCTATTTGTG
+CTAACGCCGCCCTCGGTGCCGCATGCTTTTATTACCGAATCGGATAGCGATGGTCATGTT
+CTGACGGTACGCGAAGAGCTGGTTTGGCCGCTGCTGGAAGTGCTTTATCCCGGCACCAGA
+GAGGCCTTCGGCCTGCCGGGAATCTGCCTGTCGCTGGCGGATAAACTCAACGAGCTGGCG
+GCGCTCAAACATTACTGGCAGCTAATTGAGCGGGAGTCCACGGAACAACTGGCTGGCTGC
+GAACATACCTTGGTACTACTGGCGCAGGCGGTATTTACCTTGCTGTTGCGTAATGCGAAG
+CTGGACGATCATGCCGCAACCGGGATGCGCGGTGAACTGAAACTTTTTCAGCGCTTTACC
+CTGTTAATTGACAACCACTTCCATCAGCACTGGACGGTGCCCGATTATGCCTGTGAGTTG
+CATATTACCGAATCTCGTTTGACCGATATTTGCCGACGTTTTGCTAATCGCCCGCCTAAA
+CGCCTGATTTTTGATCGGCAATTACGCGAGGCGAAACGACTGCTGCTTTTTTCCGACAAT
+GCTGTCAACGAGATCGCCTGGCAATTAGGTTTTAAAGATCCGGCTTATTTCGCCCGTTTC
+TTTAATCGCCTTGCTGGCTGTTCTCCTTCGCAGTTTCGCCAACGTGAAGTTCCTTCTTTT
+CTCAACATGATGAAAAAAAGCGTCGCTATGCTGGCGGTTTGTATGCTGGCGCAAAGCCAC
+CTTGCCATTGCTGCCGGTGCTCCTGCGCCTCAAGAGATCAACATTGTTTTACTGGGCACC
+AAAGGCGGGCCTTCTTTGCTCAATACAGCCAGACTACCGCAAGCGACGGCGCTCACTATC
+GGCGATAAGATATGGCTGATAGATGCCGGCTACGGCGCCAGTCTGCAACTGGTGAAAAAT
+GGCATTCCACTGCGCAACATCAATACTATTTTGCTCACCCATCTGCACAGCGACCACATA
+CTGGATTATCCTTCCTTGCTGATGAATGCCTGGGCAAGTGGCCTGAAAGACCATACCATA
+CAGGTTTATGGCCCGCCGGGAACCCAGGCGATGACGAAGGCTAGCTGGAAGGTCTTTGAC
+AGGGATATCACGTTACGCATGGAAGAAGAGGGGAAACCCGATCCGCGCAACCTGGTTAAG
+GCGACCGATATCGGCCAGGGCGTCATCTATAAAGATGAACTGGTCACAATAAGCGCGCTG
+AAAGTGCCTCATTCCCCTTTCCCGGACGGTGAAGCGTTTGCTTACCGTTTTGATACTCAG
+GGTAAGCGAATCGTCTTCTCTGGCGATACGTCCTGGTTTCCTCCGCTTGCAACGTTTGCC
+CAGGGGGCGGATATCCTGGTACATGAGGCGGTACATGTCCCTTCGGTAGCAAAACTGGCT
+AATAGTATTGGCAACGGAAAAACGCTGGCTGAAGCGATTGCGTCGCATCACACCACGATT
+GAAGATGTCGGTAAGATTGCTCGCGAGGCCCACGTGAAAAAACTGGTGTTAAGTCATCTG
+GTGCCTGCGACGGTTGCGGATGACGTCTGGCAACAGGAAGCCATGAAAAATTACCCGGGC
+CCTGTCATTGTCGGTCATGACAATATGACGATAAGCGTACCGATGGCTAACATCACTGTC
+ACCTTTACCATCACCGAATTTTGTTTGCACACCGGCGTGACGGAAGAGGAGCTAAACGAA
+ATCGTCGGACTTGGCGTAATTGAGCCTTACGAAGACGATAACGCCGACTGGCAATTCGAC
+GATCGCGCAGCGAGCGTGGTACAACGCGCGCTACGCTTACGCGAGGAGCTGGCGCTCGAC
+TGGCCAGGGATCGCGGTCGCGTTAACGCTGCTGGAAGAGAATTCACGGCTGCGCGAAGAA
+AACCGGTTACTGCTGCAACGCCTTTCTCGCTTTATCTCGCATCCCATGGAACTTAAGGAT
+TATTACGCCATTATGGGCGTGAAACCGACGGACGATCTCAAGACGATTAAGACCGCCTAT
+CGCCGACTGGCCCGCAAGTACCATCCAGATGTCAGCAAAGAACCCGATGCCGAAGCCCGT
+TTCAAAGAGGTTGCTGAAGCATGGGAAGTGCTGAGTGATGAGCAACGGCGCGCCGAGTAT
+GACCAGTTATGGCAACACCGTAACGATCCACAATTTAATCGCCAGTTCCAGCAACACGAA
+GGCCAGCCGTATAACGCCGAAGATTTTGATGATATTTTCTCGTCTATTTTTGGTCAGCAC
+GGTCGTCATTCGCACCACCGCCACGCCGCACGCGGTCATGATATCGAAATTGAAGTGGCG
+GTATTCCTGGAAGAAACGCTGGAAGAGCACCAGCGTACGATTAGCTATTCCGTCCCCGTT
+TATAACGCGTTCGGCCTGGTGGAGCGGGAAATTCCCAAAACATTGAATGTGAAAATCCCG
+GCTGGCGTCAGCAACGGGCAACGAATCAGACTGAAAGGCCAGGGCACGCCGGGGGAAAAC
+GGCGGACCTAATGGCGATTTATGGCTCGTTATCCATATTGCCCCGCATCCGCTCTTTGAT
+ATCGTCAATCAGGATCTGGAAGTCGTCCTTCCGCTTGCCCCATGGGAGGCGGCGCTCGGC
+GCTAAGGTGTCTGTGCCAACGCTTAAAGAGCGTATTTTGCTGACCATTCCCCCCGGCAGC
+CAGGCAGGTCAGCGGCTGCGTATCAAAGGAAAAGGATTAGCCAGTAAAAAGCACACTGGC
+GATCTCTATGCCATCATCAAAATCGTTATGCCGCCGAAACCTGACGAGAAAACAGCTGCC
+CTGTGGCAACAACTGGCGGACGCGCAGTCGTCCTTTGACCCACGCCAGCAATGGGGGAAA
+GCAATGGCGAAACAACAACGGATGGGCTGGTGGTTTCTTTGCCTTGCATGTGTCGTGGTA
+ATGGTTTGTACCGCGCAACGCATGGCGGGCCTGCACGCCTTGCAGATGCAGGCGACGGCC
+TCTGCTGCGGTGGTCAGCGCTCCCTCCTCGACAGATGACGGCTCGCCGGTCACTCCCTGC
+GAATTAAGCGCCAAGTCGCTGCTGGCGGCGCCTCCAGTACTCTTTGAAGGTGCTATCCTT
+GCGCTTTATCTACTGCTTTCCTTACTGGCGCCTGTCCGGGTCATGCGCCTGCCGTTTTCG
+CCTCCACGGGCTATTTCGCCGCCCACATTACGGGTACATCTACGATTTTGTGTCTTCCGT
+GAAATGATGATTTTATTCAGGCGGATACTGTTCTGCCTGTTATGGCTTTGGCTGCCCGTC
+TCCTGGGCGGCGGAAAGCGGCTGGCTGCGTTCGCCCGATAACGACCATGCCAGCATACGG
+CTACGTGCCGATACGTCCGCTAACAGTGAGACCCGGCTGTTGCTGGATGTCAAACTGGAA
+AACGGCTGGAAAACCTACTGGCGCGCGCCGGGGGAAGGGGGCGTGGCACCCTCTATCGCC
+TGGAAAGGCGACATGCCTGAGGTAAGCTGGTTCTGGCCAACCCCCTCGCGCTTTGATGTG
+GCGAATATCACCACCCAGGGATATCACGACGAGGTGACCTTTCCGATGATCGTGCGCGGT
+ACGCCGCCGGCGACCTTGCGCGGTGTGTTGACGTTATCAACCTGCAGCAATGTTTGTCTG
+TTGACCGATTACCCCTTTTCCGTGACGCCCACTGTGCAGAATGCCGATTTTGCCCATGAC
+TATGCGCGGGCGATGGGTAAAGTTCCGCTCCGCAGTGGGCTAACGGACTCGCTTGACGTT
+GGCTATCGCCCGGGAGAACTGGTGGTCACTGCTACGCGAGCGGCGGGCTGGTCATCGCCC
+GGGCTCTATCTTGACACCATAGATGACGTCGATTTTGCGAAGCCTCGCCTGCGCGTAGAG
+GGCGACAGGTTACAGGCGACGGTGCCGGTGACGGACAGTTGGGGCGAAAAGGCGCCCGAT
+TTGCGCGACAAATCGCTGACCCTCGTGTTAGCCGATGGCGCTATCGCCCAGGAGAGCACG
+CAAACCATTGGCGCTGCGCCAGCGCAAACGCCGGACAATGCGGCGCTACCTTTCTGGCAA
+GTTGTAATGATGGCGCTAATCGGCGGACTGATTCTTAATTTAATGCCCTGCGTACTGCCT
+GTTCTGGGCATGAAACTTGGCTCTATTTTATTGGTAGAGGAAAAAAGCCGCTCTCACATC
+AGGCGACAATTTTTGGCTTCGGTCGCCGGTATCATTGCGTCATTTATGGCGCTGGCGGCG
+TTTATGACCCTCCTTCGCCTGTCAAACCATGCGCTGGCCTGGGGAGTCCAGTTCCAGAAT
+GCATGGTTTATTGGTTTTATGGCGCTGGTGATGTTGTTGTTTAGCGCCAGCCTGTTCGGG
+CTTTTTGAGTTCAGGCTTCCCTCATCTATGACCACGAAACTGGCCACTTACGGCGGTAAC
+GGTATGTCGGGACATTTCTGGCAGGGGGCGTTCGCCACGCTGCTGGCGACGCCTTGTAGC
+GCGCCGTTTCTGGGCACGGCGGTCGCGGTGGCGCTCACGGCGTCGCTGCCGACGCTGTGG
+GGGCTGTTCCTTGCGCTTGGCCTGGGAATGAGCGCGCCGTGGCTACTGGTCGCGATACGA
+CCAGGGCTTGCGCTACGTTTACCGCGCCCCGGGCGTTGGATGAATGTCCTGCGCAGGATC
+CTCGGTCTGATGATGCTGGGGTCGGCTATCTGGCTGGCGACGTTACTCCTGCCGCATTTC
+GGCTTCACTGCGTCAAAGAGCGCGCAAGACACGGTTCAGTGGCAACCGTTGAGTGAACAG
+GCAATCCAGTCGGCGCTGGCGCAGCATAAGCGGGTATTTGTCGATGTCACTGCGGACTGG
+TGTATTACCTGTAAAGTGAATAAATACAACGTCCTGCAAAAAGAGGATGTGCAGGCCGCC
+TTGCAACAGCCGGATGTTGTGGCGCTGCGGGGAGACTGGACGCTGCCGTCCGATGCCATT
+ACAGATTTTCTGAAAACGCGCGGCCAGGTCGCCGTGCCGTTTAATCAGGTATATGGCCCC
+GGTTTGCCGGAAGGGGAGGCACTGCCCACTTTGCTGACCCGCGATGCGGTATTACAAACG
+TTGAAAAAAGCGAAAGGAATAACCCAAATGAAATACATGATTGTTTTACTGCTGGCGCTG
+TTTTCGACGCTGAGCATCGCGCAAGAAACCGCTCCTTTTACGCCGGATCAGGAAAAGCAG
+ATTAAAAATCTGATCCATGCGGCGTTGTTTAACGATCCTGCCAGCCCGCGGATAGGCGCT
+AAACACCCTAAGCTGACGCTGGTGAACTTTACGGATTACAACTGCCCGTACTGCAAACAG
+CTCGATCCGATGCTGGAAAAGATTGTGCAGAAATATCCTGACGTTGCGGTCATTATTAAA
+CCGCTGCCATTCAAAGGAGAGAGTTCCATACTGGCGGCGCGTATTGCGCTGACCACCTGG
+CGCGATCATCCGCAACAGTTCCTCGCGCTACATGAAAAACTTATGCAAAAGCGCGGTTAC
+CATACGGATGACAGTATTAAACAGGCCCAGCAGAAAGCAGGGGCGACGCCAGTGACGCTG
+GATGAAAAAAGCATGGAAACGATACGCACTAATTTGCAGTTGGCAAGACTGGTCGACGTG
+CAAGGAACGCCAGCGACGATCATTGGCGACGAGCTGATTCCGGGCGCAGTGCCCTGGGAT
+ACGCTGGAAGCGGTGGTGAAAGAAAAACTGGCGGCTGCCAATGGCGGGATGGCGGGTAAA
+CTGCGGCGTTGGCTGCGTGAAGCCGCGGTTTTTCTGGCGCTCCTCATCGCGATAATGGTG
+GTCATGGACGTCTGGCGCGCGCCGCAGGCGCCTCCGGCGTTTGCCGCGACACCATTACAT
+ACGCTGACGGGAGAGTCGACAACTCTGGCGACCTTGAGCGAGGAACGCCCCGTACTGCTC
+TATTTTTGGGCCAGCTGGTGCGGGGTATGCCGCTTTACCACGCCTGCGGTCGCTCACCTG
+GCGGCGGAAGGGGAAAACGTCATGACCGTTGCGCTCCGCTCCGGCGGTGATGCTGAGGTT
+GCCCGCTGGCTGGCGCGCAAGGGCGTTGACTTCCCGGTCGTCAATGATGCTAACGGCGCC
+TTATCCGCTGGCTGGGAAATCAGCGTGACGCCAACGCTGGTGGTGGTTTCACAAGGTCGG
+GTTGTGTTCACCACCAGCGGCTGGACCAGCTATTGGGGCATGAAGCTTCGGCTGTGGTGG
+GCAAAAACGTTCATGAAAAAATCATTACTCGCTGTTGCTGTGGCAGGGGCTGTTTTGTTG
+TCATCCGCCGTACAGGCGCAGACAACGCCGGAAGGTTATCAATTACAACAGGTGCTGATG
+ATGAGCCGCCATAATCTGCGGGCGCCGCTGGCGAATAATGGCAACGTACTGGCGCAGTCG
+ACGCCGAACGCCTGGCCGGCGTGGGACGTTCCCGGCGGGCAACTGACGACGAAAGGCGGC
+GTGCTGGAAGTCTATATGGGACACTACACACGTGAATGGCTGGTCGCGCAGGGGCTGATA
+CCGTCGGGAGAATGTCCGGCGCCCGACACGGTATATGCCTATGCGAATAGTTTGCAGCGC
+ACCGTCGCCACCGCGCAATTTTTCATTACCAGCGCTTTCCCCGGCTGTGATATTCCTGTT
+CATCATCAGGAAAAAATGGGCACTATGGACCCTACCTTCAATCCGGTGATTACCGATGAT
+TCCGCCGCGTTCCGGCAACAGGCCGTACAGGCGATGGAAAAGGCGCGTAGTCAGCTACAT
+CTTGATGAGAGTTATAAACTGCTTGAGCAGATAACGCATTATCAGGACTCGCCGTCCTGC
+AAAGAGAAGCATCAGTGTTCGCTAATCGACGCGAAAGATACCTTCAGCGCGAACTATCAG
+CAAGAGCCTGGCGTGCAGGGGCCGCTGAAAGTAGGGAACTCGCTGGTGGATGCGTTTACC
+CTGCAATATTACGAAGGCTTTCCGATGGATCAGGTCGCTTGGGGCGGGATCCACACCGAT
+CGGCAGTGGAAGGTGCTGTCAAAACTGAAAAACGGCTACCAGGACAGCCTGTTTACCTCA
+CCCACGGTGGCGCGCAATGTCGCTGCGCCGCTGGTAAAATATATCGATAAGGTGCTGGTT
+GCCGAGCGCGTTAGCGCGCCGAAGGTTACCGTGCTGGTGGGGCATGATTCCAATATCGCG
+TCGCTGCTGACGGCGCTGGATTTTAAACCCTATCAGCTCCATGACCAGTATGAGAGAACG
+CCGATTGGTGGTCAGCTTGTCTTCCAACGCTGGCATGACGGTAACGCTAACCGGGATTTG
+ATGAAAATCGAGTATGTCTACCAGAGCGCCCGGCAGTTACGTAATGCGGAAGCGTTAACG
+CTCAAATCGCCTGCGCAAAGGGTAACGCTGGAACTGAAAGGATGTCCGGTGGATGCGAAC
+GGCTTCTGTCCGCTGGATAAGTTCGATAACGTCATGAACACTGCTGCAAAAATGCCAACT
+CAAGAAGCAAAAGCGCACCGCGTCGGCGAATGGGCAAGCCTGCGTAATACGTCGCCGGAA
+ATTGCCGAAGCCATTTTTGAAGTCGCTCACTATGACGAGAAACTGGCAGAAAAAATATGG
+GAAGAAGGTAGCGATGAGGTGCTGATCAAAGCCTTTGAGAAAACGGACAAAGACTCGCTC
+TTCTGGGGCGAACAAGTCATCGAACGTAAGAACGTAATGGCAAAGATTCTGGTGCTCTAT
+TATTCCATGTACGGACACATTGAAACCATGGCGCACGCGGTGGCGGAAGGGGCAAAGAAA
+GTCGACGGCGCAGAGGTCATTATAAAGCGTGTGCCAGAAACAATGCCGCCTGAAATCTTC
+GCAAAAGCTGGCGGTAAAACGCAAAACGCACCGGTTGCCACCCCACAGGAGCTGGCGGAT
+TACGATGCCATTATTTTTGGTACGCCAACCCGGTTTGGCAATATGTCAGGCCAGATGCGT
+ACCTTCCTGGACCAAACCGGCGGACTGTGGGCATCCGGCGCGCTATACGGCAAGCTCGGC
+GGCGTGTTCAGTTCTACCGGAACGGGCGGCGGCCAGGAGCAGACCATCACCTCGACCTGG
+ACTACGCTTGCCCATCATGGGATGGTGATTGTCCCGATAGGCTATTCCGCACAGGAACTG
+TTTGACGTCTCCCAGGTTCGCGGCGGTACGCCTTACGGCGCAACGACTATCGCTGGAGGC
+GACGGTTCACGTCAACCAAGCCAGGAGGAACTCTCTATCGCTCGCTATCAGGGGGAATAC
+GTCGCCGGTCTGGCAGTCAAACTCAACGGCATGGCAAACCATCGTGGCGGTTCCGGTAAT
+TTTGCGGAAGACCGCGAAAGAGCATCAGAAGCAGGTCGTAAAAGTGGTCAGCACAGCGGG
+GGCAATTTTAAGAATGACCCGCAGCGTGCATCCGAAGCAGGCAAAAAAGGGGGCAAAAGC
+AGTAACCGTAATCGCATGTCGCAACGCACAGAGAAAAAAATCGGGAAACGTTCGCAGGCC
+ACCGGTGCAAAACGGCAGCTTATCTTAACCGCCGCGCTTGCCGTTTTTTCCCAGTATGGC
+ATTCATGGCGCGCGTCTTGAACAGGTCGCCGAGCGGGCAGGCGTCTCCAAAACCAATCTG
+CTTTATTATTATCCCTCGAAAGAGGCGCTGTATGTCGCGGTAATGCGACAGATTCTGGAT
+GTCTGGTTGGCGCCGCTCAAGGCGTTTCGCGCAGAATTTTCCCCTCTGGAGGCCATCAAA
+GAGTATATCCGTCTCAAGCTGGAGGTTTCGCGTGATTATCCGCAGGCGTCGCGGCTCTTC
+TGCATGGAGATGCTGGCGGGCGCGCCGCTCTTAATGGATGAACTGACCGGCGATCTAAAA
+GCGTTGATAGATGAAAAATCCGCGCTGATTGCCGGATGGGTGCACAGCGGGAAACTCGCG
+CCCGTTTCTCCGCATCATTTGATCTTCATGATTTGGGCCGCCACGCAACATTACGCCGAT
+TTCGCCCCTCAGGTTGAAGCGGTAACCGGCGCGACGCTTCGCGATGAAGCCTTTTTCAAC
+CAAACGGTCGAAAGCGTTCAGCGCATTATTATTGAAGGGATTCGCGTGCGTATGAAACGA
+ATTTTCCTTACCTGCGCGGCGTTGTTGTTCAGCAGTCAGGCGTTGGCCGATGAGTGTGCC
+AGCGCCAGTACGCAGCTGGAAATGAATCGCTGCGCCGCCGCGCAATACCAGGCGGCAGAT
+AAAAAGCTGAACGAAACCTATCAAAGCGCGATTAAGCGTGCGCAACCGCCGCAGCGTGAG
+CTATTGCAAAAAGCGCAGGTGGCATGGATTGCCCTGCGCGACGCCGATTGCGCGCTGATT
+CGCTCAGGTACGGAGGGCGGCAGCGTTCAACCCATGATCGCCAGCCAGTGCCTGACCGAT
+AAAACGAACGAACGCGAAGCGTTTTTAGCCTCGCTGCTGCAATGTGAAGAGGGTGATTTG
+AGCTGCCCACTGCCGCCAGCCGGTATGGGAACCACCACGATGGGGGTTAAGCTGGACGAC
+GCCACGCGCGAACGGATCAAAATGGCCGCGTCGCGTATCGATCGCACGCCGCACTGGTTA
+ATAAAACAGGCAATCTTTAGCTATCTGGACAAGCTGGAAAATAGCGATACGCTACCGGAG
+CTACCTGCGCTGTTTGCCGGCGCGGCAAATGAAAGCGAGGAGCCGGTCGCGCCGCAGGAT
+GAGCCGCATCAGCCCTTTCTGGAGTTTGCCGAACAGATTCTTCCCCAATCCGTCTCTCGC
+GCCGCCATCACCGCCGCCTGGCGCCGCCCGGAAACCGATGCGGTGTCAATGCTAATGGAA
+CAGGCGCGCCTGTCGCCGCCTGTCGCTGAGCAGGCGCATAAACTGGCGTATCAACTGGCG
+GAGAAATTGCGCAATCAAAAATCCGCCAGCGGTCGCGCGGGTATGGTGCAAGGCCTGTTG
+CAGGAGTTTTCCCTCTCTTCGCAAGAAGGCGTAGCGCTGATGTGTCTGGCGGAAGCGCTG
+CTGCGTATTCCCGACAAAGCTACGCGCGATGCGTTAATTCGCGACAAAATCAGTAATGGC
+AACTGGCAGTCGCATATTGGCCGTAGCCCGTCGCTGTTTGTAAACGCCGCCACCTGGGGG
+CTGCTCTTTACCGGCCGACTGGTCTCAACGCATAACGAAGCCAATCTTTCGCGCTCGCTG
+AACCGCATTATCGGCAAGAGCGGCGAACCGTTAATCCGCAAAGGCGTCGACATGGCGATG
+CGTTTAATGGGCGAGCAGTTCGTGACTGGCGAAACCATTGCTCAGGCGCTGGCGAATGCC
+CGAAAACTGGAAGAGAAAGGGTTCCGCTATTCTTACGATATGCTGGGCGAAGCCGCGTTA
+ACCGCCGCCGATGCGCAGGCCTATATGGTCTCTTACCAGCAAGCGATTCATGCCATCGGC
+AAAGCGTCTAACGGTCGCGGTATTTACGAAGGGCCAGGCATCTCGATTAAGCTGTCCGCC
+CTGCATCCACGCTATAGTCGCGCGCAATACGATCGGGTAATGGAGGAGCTTTATCCGCGC
+CTGAAATCCCTGACGCTGCTGGCGCGCCAGTATGATATCGGTCTCAATATCGACGCCGAA
+GAGGCGGATCGTCTGGAGATCTCGCTTGATCTGCTGGAAAAACTCTGCTTCGAACCCGAA
+CTGGCGGGCTGGAACGGCATTGGCTTTGTGATTCAGGCTTACCAGAAACGCTGCCCGCTG
+GTCATTGATTATTTAGTCGATCTGGCCTCCCGTAGCCGCCGTCGGCTGATGATTCGTCTG
+GTGAAAGGCGCCTACTGGGATAGCGAGATCAAACGCGCGCAAATGGAAGGGCTGGAGGGC
+TATCCAGTTTATACCCGCAAAGTGTATACCGATGTCTCTTATCTGGCCTGCGCGAAAAAA
+CTGCTCGCCGTCCCTAATCTGATCTACCCGCAGTTCGCGACCCATAACGCTCACACACTG
+GCGGCGATTTATCATCTGGCCGGGCAAAATTACTATCCGGGTCAGTACGAATTCCAGTGC
+CTGCACGGCATGGGAGAACCGCTGTATGAACAGGTCACCGGTAAAGTGGGGGACGGAAAA
+CTTAACCGTCCCTGCCGTATTTACGCGCCGGTGGGAACACACGAAACCCTGCTGGCCTAT
+CTGGTACGACGCCTGCTGGAAAACGGCGCCAACACCTCTTTTGTCAACCGCATCGCCGAT
+GCCACCCTACCGCTCGATGAACTGGTGGCCGACCCGGTCGAGGCCGTGGAAAAACTGGCG
+CAGCAGGAAGGTCAGGCTGGCATACCGCATCCAAAAATTCCGCTGCCGCGCGATCTGTAC
+GGCGAAGGTCGGATAAACTCCGCCGGACTTGATTTAGCGAATGAACATCGCCTCGCCTCG
+CTTTCTTCTGCCCTGTTAAGCAACGCCATGCAGAAATGGCAGGCCAAACCTGTGCTGGAA
+CAACCGGTGGCCGACGGTGAGATGACGCCGGTTATCAACCCGGCGGAACCGAAAGATATT
+GTTGGCTGGGGACGCGAAGCGACAGAAAGCGAGGTTGAACAGGCGTTGCAAAACGCGGTC
+AATCAGGCGCCGGTTTGGTTTGCGACGCCGCCGCAAGAACGCGCCGCTATTTTGCAGCGG
+GCGGCGGTATTGATGGAAGACCAAATGCAGCAGTTGATTGGCCTGTTGGTGCGTGAAGCG
+GGGAAAACGTTCAGCAACGCCATTGCCGAAGTGCGCGAAGCGGTAGACTTCCTCCATTAT
+TATGCCGGTCAAGTGCGTGACGATTTCGATAACGAAACGCATCGCCCGTTAGGGCCGGTG
+GTCTGTATCAGTCCGTGGAACTTTCCGCTGGCCATTTTCACTGGCCAAATCGCCGCCGCG
+CTGGCGGCAGGTAACAGCGTTCTGGCGAAACCGGCAGAGCAGACATCGCTGATTGCCGCC
+CAGGGCATTGCCATTTTGCTGGAAGCGGGCGTACCGCCGGGCGTCGTGCAACTGTTGCCG
+GGACGGGGAGAAACCGTCGGCGCCCAGCTTACCGCCGATGCGCGTGTACGCGGCGTGATG
+TTTACCGGTTCCACGGAGGTCGCGACGTTGTTGCAGCGCAACATCGCCACGCGTCTTGAC
+GCCCAGGGGCGCCCTATTCCGTTGATTGCGGAAACCGGCGGTATGAACGCTATGATTGTC
+GACTCTTCCGCGCTCACCGAGCAGGTGGTCGTGGATGTGCTGGCTTCCGCCTTCGACAGC
+GCCGGACAACGCTGTTCCGCGCTCCGCGTGCTGTGTTTGCAGGACGATATCGCCGAACAT
+ACGCTGAAAATGTTACGCGGCGCGATGGCGGAGTGTCGGATGGGGAATCCAGGCCGTCTG
+ACGACCGATATCGGGCCGGTGATCGATAGCGAGGCCAAAGCCAACATTGAACGTCATATC
+CAGACGATGCGCGCCAAAGGCCGCCCGGTTTTCCAGGCCGCGCGTGAAAACAGCGATGAC
+GCGCAGGAATGGCAGACCGGTACGTTTGTTATGCCCACGCTTATTGAGCTGGAAAACTTC
+GCAGAACTGGAAAAAGAGGTCTTCGGGCCCGTGCTGCACGTCGTGCGTTATAACCGTAAC
+CAACTGGCGGAGCTTATCGAACAGATTAACGCTTCCGGCTACGGGCTAACGCTGGGCGTA
+CATACCCGTATTGATGAAACCATTGCGCAAGTCACCGGTTCCGCCCATGTCGGCAACCTG
+TACGTTAACCGTAATATGGTGGGCGCGGTCGTCGGCGTCCAGCCGTTTGGCGGCGAAGGC
+CTGTCCGGCACCGGGCCAAAAGCGGGAGGGCCGCTCTATCTCTACCGCCTGCTGGCACAC
+CGCCCGCCCAATGCGCTCAATACGACGCTGACTCGTCAGGATGCGCGTTACCCGGTGGAT
+GCGCAGCTTAAAACCACGCTACTCGCGCCGTTGACCGCTCTGACGCAATGGGCGGCGGAT
+CGCCCGGCGCTACAGACGCTCTGCCGACAATTCGCCGATCTGGCGCAGGCCGGCACGCAG
+CGCCTGCTACCGGGGCCGACCGGCGAGCGTAATACCTGGACGCTGTTGCCGCGTGAACGG
+GTGTTATGCCTGGCTGATGATGAACAGGACGCGTTGACGCAGCTTGCCGCCGTTCTCGCC
+GTCGGCAGTCAGGCGCTATGGTCAGACGACGCCTTCCACCGCGATCTGGCGAAACGTCTC
+CCCGCCGCCGTCGCGGCGCGTGTCCAGTTTGCGAAAGCGGAAACGCTGATGGCGCAGCCG
+TTTGACGCGGTGATTTTCCACGGCGACTCCGACAAGCTGCGAACCGTGTGCGAAGCCGTC
+GCCGCCCGCGAAGGCGCGATAGTGTCGGTACAGGGGTTCGCCCGCGGCGAAAGCAATATG
+CTGCTGGAACGGCTCTATATTGAACGTTCGCTGAGCGTAAACACTGCCGCCGCTGGCGGT
+AATGCCAGCCTGATGACAATTGGCATGGCTATTAGCACACCGATGTTGGTGACATTCTGT
+GTCTATATTTTTGGCATGATATTGATTGGGTTTATCGCCTGGCGCTCAACCAAAAACTTT
+GATGACTATATTCTTGGCGGTCGCAGCCTGGGGCCGTTTGTTACGGCTTTATCAGCCGGC
+GCGTCGGATATGAGCGGCTGGCTGTTAATGGGGCTGCCTGGCGCTATCTTTCTGTCGGGG
+ATCTCTGAAAGCTGGATCGCCATTGGCCTGACGTTAGGCGCATGGATTAACTGGAAGCTG
+GTGGCCGGGCGCCTGCGCGTGCATACCGAATTTAACAATAACGCGCTCACGCTGCCGGAC
+TATTTTACCGGTCGGTTTGAGGATAAGAGCCGAGTCCTGCGTATTATTTCCGCGCTGGTC
+ATTCTGCTGTTTTTCACTATCTATTGCGCATCAGGTATTGTCGCTGGGGCACGACTGTTC
+GAAAGCACCTTCGGTATGAGCTATGAAACCGCACTGTGGGCGGGGGCCGCGGCAACCATT
+ATTTATACCTTTATCGGCGGGTTTCTTGCCGTTAGCTGGACGGATACCGTTCAGGCCAGC
+CTGATGATTTTTGCGTTAATCCTGACGCCGGTGATGGTTATTGTCGGCGTAGGCGGTTTT
+AGCGAGTCGCTGGAAGTGATCAAGCAAAAGAGCATCGAGAATGTCGACATGCTCAAGGGG
+CTGAATTTTGTCGCTATTATTTCTCTGATGGGCTGGGGGCTGGGTTACTTCGGTCAGCCG
+CATATCCTGGCGCGCTTTATGGCGGCGGATTCCCATCACAGTATTGTTCATGCGCGTCGT
+ATCAGTATGACCTGGATGATTCTGTGTCTGGCGGGCGCGGTGGCGGTGGGCTTCTTTGGC
+ATTGCGTACTTTAACAATAACCCCGCGCTGGCCGGGGCGGTGAACCAAAACTCAGAACGC
+GTATTTATTGAACTGGCGCAGATCCTGTTTAACCCGTGGATTGCCGGTGTTCTGCTGTCT
+GCTATCCTGGCGGCGGTGATGTCGACGTTGAGCTGTCAGTTGCTGGTATGCTCCAGCGCG
+ATTACGGAAGATTTATATAAGGCTTTTCTGCGTAAAAGCGCCAGCCAGCAAGAGCTGGTA
+TGGGTAGGGCGAGTGATGGTGCTGGTGGTAGCGCTGATCGCCATTGCGCTGGCGGCGAAT
+CCTGATAACCGTGTGCTGGGGCTGGTGAGCTACGCCTGGGCTGGATTCGGCGCGGCATTT
+GGACCTGTTGTCCTGTTTTCTGTGATGTGGTCGCGTATGACACGTAACGGCGCGCTGGCG
+GGAATGATTATTGGCGCGGTGACGGTTATCGTCTGGAAACAATATGGCTGGCTGGATCTG
+TATGAGATTATCCCTGGCTTCATTTTCGGCAGCCTGGGGATCGTAATCTTTAGCCTGCTT
+GGCAAAGCGCCGACAGCAACGATGCAGGAACGCTTTGCAAAAGCGGACGCGCATTATCAT
+TCCGCGCCGCCGTCGAAGCTACAGGCGGAAATGGTAATGTCCGCACCAGGACACATTGTT
+TACAGTAGTTACAACACCCTGTACGGACATTCTCTCTCCGGTGGTGGTCTTGTCATCTTA
+AAAGCTCTCATCATTTCCCTTACTGTCCATACCCATGACGCCATATGTGGTGCGCGTAGC
+CGTGTGTGGCGTCGTTTCAAAAAGCAAGCTAAGGCTTACAAGGAAGCCAACCCTCAGATG
+TGTGTGCGCATAATCGCGTTCAAGAGAACGCGGGTGATGTATACCTACAACTCAAGGTGC
+TATCCATGGGAAGACAAAAAGCAGATGGGAAGACAAAAAGCAGTGATCAAAGCTCGTCGT
+GAAGCAAAGCGTGTGTTGAGACGAGATTCGCGTAGTCATAAGCAACGTGAAGAAGAATCG
+GTCACGTCACTGGTACAGATGGGCGGAGTAGAAGCCATTGGCATGGCGCGCGATAGTCGC
+GATACCTCTCCTGTTAAGGCGCGAAATGAAGCACAGGCGCATTATCTGAACGCTATCGAC
+AGTAAACAGCTTATTTTTGCGACCGGCGAAGCCGGCTGCGGAAAAACATGGATCAGTGCG
+GCAAAGGCGGCAGAAGCATTGATTCATAAGGACGTCGAGAGGATCATTGTGACGCGTCCG
+GTATTGCAGGCTGATGAAGATCTTGGTTTTTTGCCCGGTGATATCGCTGAAAAATTCGCG
+CCTTATTTTCGTCCCGTCTACGATGTCCTGCTTAAACGGTTGGGCGCGTCCTTTATGCAA
+TATTGTTTGCGCCCGGAAATCGGTAAGGTAGAAATTGCCCCGTTCGCCTATATGCGTGGG
+CGTACTTTTGAAAATGCGGTCGTGATCCTCGACGAGGCGCAAAATGTGACTGCGGCGCAA
+ATGAAAATGTTTTTGACGCGATTAGGCGAAAATGTCACGGTCATTGTCAATGGCGATATT
+ACGCAATGCGACCTGCCGCGCGGTGTGCGTTCCGGGTTGAGTGATGCGTTGGAACGCTTT
+GAAGAAGATGAAATGGTGGGGATTGTGCATTTCAACAAAGACGACTGCGTGCGCTCGGCG
+CTTTGTCAGCGAACGCTCCACGCATACAGCATGGAGCCTCAACCCCCACGTCTTAAACCC
+GGAAAAATCCTTGACACTCTGGGTGCTATGCAAAAAAGCCTGACACGTGCCTCCCAGCGT
+ATTGCGCAATATATTTTAGCCTTCCCCAGACAGGTGACACAGTCATCTATTGCCGATTTG
+TCGCGCGACACACAGGCCGGAGAAGCCACGGTTATTCGCTTTTGTCGCACCCTGGGCTAT
+AAAGGTTTTCAGGATTTTAAAATGGACCTGGCCATTGAACTTGCCACTACCGAGTCTGAT
+GACAGTAGTCCTCTACTGGATGCCGAAGTTAGCGAATCCGACGATGCCCACGCCATTGGT
+TTAAAATTGCAGAACACCATTAGTAATGTATTATCTGAAACGCTAAATCTGCTTGATATG
+CAACAGGTTCTCGGTGTCGTGGACGCCCTACGTCACTGTCACTCAGTTTATATCTTTGGT
+GTGGGCTCATCGGGGATCACGGCGCTGGATATGAAACACAAGCTAATGCGTATTGGTTTA
+CGGGGCGATGCGGTAAGCAATAACCATTTTATGTACATGCAGGCTACGCTATTAAAAGCA
+GGCGATGTCGCGATGGGTGTCAGTCACTCGGGCACATCGCCAGAAACAGTGCATTCACTC
+CGATTGGCCCGACAGGCTGGCGCCACCACAGTCGCCATTACCCATAATCTGGGTTCTCCA
+TTATGTGAAGAGGCCGATTTTTGCCTGATCAATGGTAATCGGCAAGGAATGTTGCAGGGT
+GACTCGATCGGTACGAAAGCCGCGCAGCTTTTCGTCTTTGACCTGCTCTATACCCTTCTT
+GTACAGTCCTCGCCGGAACAGGCCCGAGAAAGCAAATTACGGACAATGAATGCCCTGGAC
+ATGACAAAAGTGATATGTCTCAAAGTCCAGGGCGGCATTGGTGAAATTTTTACGGTGACG
+CAGCAGGCGGATAAATTCTTTCCGGCTACGCAGTTCCACTGGAGCTGGACGGAAAGCACA
+GTACCTGTATTGATGATTGGTTTTCTGTTTGCCAATATTCAGCAATTTACTGCCAGTCAG
+GATGTGGTCCAACGCTATATCGTGACTGACTCCATAGAGGAAACGAAGAAAACATTACTT
+ACAAATGCCAAACTGGTTGCTGTGATCCCTGTTTTCTTTTTTGCTATCGGCTCGGCATTA
+TTTGTCTACTATCAGCAACATCCACAATTATTACCGGCGGGATTCAACACTGGCGGCATT
+TTGCCCTTATTCGTGGTCACCGAAATGCCAGTCGGCATTGCAGGGTTGATAATCTCCGCT
+ATTTTCGCTGCCGCGCAGTCCAGCATCTCCAGCAGCTTAAACAGCATTTCCAGTTGTTTT
+AATTCCGATATCTATCAGCGTTTGAGTCATAAAAAAGGAACGCCAGAAAACCGTATGAAA
+ATAGCTAAGTTAGTTATTCTGGTCGCGGGCCTGATAAGTAGCGCGGCCTCGGTATGGCTG
+GTCATGGCCGATGAATCAGAAATCTGGGATGCATTTAATAGTCTGATAGGTCTGATGGGA
+GGGCCAATGACCGGTCTGTTCATGCTGGGCATTTTCTTTAAACGAGCAAATGCCGGGAGT
+GCGGTTTTAGGAATTATTATCAGCGTCATTACCGTGCTGGGCACACGCTATGCCACTGAC
+CTTAACTTCTTCTTTTATGGGGTCATTGGCTCGCTAAGCGTGGTGATCAGCGGCGTTATT
+TTCGCCCCGTTATTTGCCCCGGCACCGCCATTGACGCTGGATGAAAAACCTGAACCAAAG
+GTGACATTAATGTCACTATTAGCCAGGCTGGAACAAAGTGTACACGAAAACGGTGGGCTG
+ATTGTCTCATGCCAACCGGTACCAGGCAGCCCTATGGATAAACCTGAAATTGTGGCTGCA
+ATGGCACAGGCAGCGGCTTCGGCGGGTGCGGTCGCTGTGCGCATTGAAGGCATTGAGAAT
+CTGCGGACTGTTCGTCCCCATCTTTCTGTTCCTATTATTGGGATAATTAAACGTGACCTT
+ACAGGGTCGCCAGTCCGTATCACTCCATATTTACAGGATGTTGACGCCCTGGCGCAGGCA
+GGTGCCGATATTATCGCTTTTGATGCCTCATTCCGCTCTCGCCCGGTTGATATTGATAGT
+TTACTGACACGTATTCGCCTGCATGGATTACTGGCGATGGCAGACTGTTCAACCGTGAAT
+GAAGGCATAAGTTGCCATCAGAAAGGAATCGAATTCATTGGTACAACACTGTCTGGCTAT
+ACCGGTCCCATCACGCCGGTTGAGCCAGATTTGGCAATGGTGACACAACTGAGTCATGCA
+GGTTGTCGTGTTATTGCCGAGGGGCGCTATAACACGCCTGCACTGGCGGCCAATGCTATT
+GAGCATGGTGCCTGGGCAGTTACCGTTGGTTCCGCTATCACCCGTATCGAGCATATCTGT
+CAGTGGTTCAGTCACGCAGTAAAACGCATGAAAAATTTTAAGAAAATGATGACGCTAATG
+GCGCTATGTTTATCAGTTGCTATCACCACATCAGGATATGCAACCACGCTTCCTGATATA
+CCAGAACCACTGAAAAATGGTACTGGCGCTATTGATAATAATGGCGTGATTTATGTCGGC
+TTAGGTACCGCAGGGACATCCTGGTATAAAATTGATCTTAAAAAGCAACATAAAGACTGG
+GAGCGTATAAAGTCGTTTCCTGGTGGAGCTCGTGAGCAATCCGTGTCGGTATTTTTAAAT
+GATAAGCTGTATGTTTTTGGTGGCGTAGGGAAAAAAAACAGTGAATCACCGTTGCAGGTT
+TATAGCGATGTGTACAAATACTCACCGGTGAAAAATACATGGCAAAAAGTTGATACTATA
+TCTCCAGTTGGATTAACAGGGCATACGGGAGTAAAATTAAACGAAACGATGGTACTTATT
+ACCGGAGGGGTTAATGAGCATATCTTTGATAAGTATTTTATTGATATAGCGGCTGCGGAT
+GAAAGTGAAAAAAATAAAGTCATCTATAATTATTTTAATAAACCTGCCAAAGATTATTTT
+TTTAATAAAATCGTATTTATCTACAATGCTAAAGAGAACACATGGAAGAATGCCGGTGAG
+CTGCCAGGCGCGGGGACGGCAGGATCGTCATCGGTAATGGAAAATAATTTCTTGATGCTG
+ATTAATGGTGAGCTCAAACCGGGTTTACGTACCGATGTGATTTACCGCGCCATGTGGGAT
+AACGATAAGCTAACATGGTTGAAGAACAGCCAGTTACCGCCATCGCCTGGAGAACAACAG
+CAGGAAGGGTTGGCCGGAGCATTTTCGGGCTATAGCCACGGTGTCCTGCTTGTCGGTGGT
+GGCGCGAATTTTCCGGGAGCAAAACAAAATTATACTAATGGAAAGTTTTATTCCCACGAA
+GGGATAAATAAAAAATGGCGAGATGAAGTCTATGGTTTGATTAATGGCCATTGGCAATAT
+ATGGGTAAAATGAAACAACCTCTCGGCTATGGTGTATCAGTAAGTTATGGTGATGAAGTT
+TTCCTTATTGGTGGTGAAAATGCTAAAGGGAAACCTGTTTCGTCTGTAACCTCCTTTACC
+ATGCGTGATGGTAATTTATTAATAAAAATGAAAATCAACAGATATCTTCTGGGTATGGTT
+TCGTTTATAGCATTTTCATCATATCTACAAGCGGCAACCCTTGATTATCGGCATGAATAT
+GCTGATAGAACCAGAATTAATAAAGACCGTATTGCTATAATTGAAAAGCTTCCTAACGGC
+ATTGGTTTTTATGTCGATGCCAGCGTTAAATCGGGAGGAGTAGATGGTGAGCAGGATAAG
+CATTTAAGCGATCTCGTCGCAAACGCTATAGAACTGGGCGTAAGTTATAATTATAAAGTT
+ACGGACCATTTTGTTTTGCAGCCTGGATTTATATTTGAAAGCGGTCCAGACACTTCAATT
+TATAAGCCTTATTTAAGGGCGCAATATAATTTTGATTCTGGTGTTTATATGGCTGGTCGT
+TACCGTTATGACTATGCAAGGAAGACAGCTAACTATAATGATGATGAGAAAACGAATAGA
+TTTGATACTTATATAGGTTATGTTTTTGATGAGTTGAAATTGGAATATAAATTTACCTGG
+ATGGATAGCGATCAAATTAAATTTGATAACAAAAAAACAAACTATGAACATAATGTGGCT
+TTAGCCTGGAAACTGAATAAGTCATTTACACCATACGTTGAGGTCGGAAATGTAGCGGTG
+AGAAATAATACCGATGAGAGACAGACCCGTTATCGCGTTGGATTACAATACCACTTTGTG
+ATAGCAAAATTCTTCCCGTGGTATAGCGAGATAACACGTCCACAAAAAAATGCTTTATTT
+TCAGCATGGCTGGGTTACGTTTTTGATGGCTTCGACTTTATGCTGATTTTCTACATTATG
+TATCTGATCAAGGCTGACTTAGGATTGACAGATATGGAGGGCGCATTCCTTGCCACAGCG
+GCCTTTATTGGGCGACCATTTGGCGGGGCGCTATTTGGTCTGCTGGCAGACAAATTTGGC
+CGTAAGCCGTTAATGATGTGGTCGATAGTTGCCTATTCTGTAGGTACAGGGTTAAGTGGC
+CTGGCTTCCGGTGTAATTATGCTGACGCTTAGTCGTTTTATTGTCGGTATGGGGATGGCG
+GGGAAGTATGCTTGCGCTTCTACTTATGCCGTGGAAAGTTGGCCAAAGCATTTAAAATCT
+AAAGCGAGCGCATTTCTGGTTTCAGGTTTCGGTATTGGTAACATCATAGCAGCCTATTTT
+ATGCCGTCATTTGCCGAAGCGTATGGTTGGCGTGCTGCTTTTTTTGTCGGTTTGCTACCC
+GTTCTTTTAGTAATCTACATCCGGGCCAGGGCTCCTGAATCTAAAGAGTGGGAAGAAGCC
+AAACTCAGTGGTCTCGGAAAGCATTCACAAAGTGCCTGGTCAGTTTTCTCTTTGTCAATG
+AAAGGGCTATTTAATCGAGCTCAATTTCCACTGACATTATGTGTATTTATTGTTCTGTTC
+TCTATTTTCGGCGCAAACTGGCCGATCTTTGGTCTACTGCCTACATATTTGGCGGGAGAG
+GGCTTTGATACGGGCGTGGTCTCTAATTTAATGACGGCGGCGGCATTCGGCACTGTATTG
+GGAAATATCGTTTGGGGTCTGTGCGCAGATAGAATTGGTTTGAAGAAAACGTTCAGCATT
+GGTCTTCTCATGTCCTTTTTATTCATTTTCCCGTTATTCAGAATTCCGCAAGATAATTAT
+TTACTGCTGGGCGCATGTTTATTCGGTTTAATGGCGACTAACGTAGGTGTTGGCGGGCTG
+GTTCCCAAATTTCTCTACGACTACTTTCCTCTTGAGGTTCGTGGTTTGGGTACCGGGCTT
+ATTTATAATCTTGCTGCGACATCAGGCACATTCAATTCAATGGCGGCGACCTGGCTTGGA
+ATAACAATGGGGCTAGGCGCTGCGCTAACGTTCATTGTTGCTTTCTGGACCGCAACAATT
+CTACTCATTATTGGCCTATCCATTCCGGATAGACTAAAAGCACGTCGTGAAAGGTTTCAG
+TCAACAAAAGAATTTATGACGAAATACGGTGTTATAGGTACAGGTTATTTTGGCGCTGAA
+CTGGCGCGATTTATGTCTAAGGTTGAAGGGGCGAAAATCACTGCGATTTACGATCCGGTA
+AATGCGGCTCCGATAGCGAAAGAGCTGAACTGTGTCGCCACTTCAACGATGGAGGCGCTT
+TGTACCCATCCTGATGTGGATTGCGTAATTATTGCTTCACCAAATTACTTACATAAAGCG
+CCGGTCATTGCGGCGGCTAAAGCGGGTAAACACGTGTTTTGTGAAAAACCTATCGCCTTA
+AATTACCAGGATTGTAAGGATATGGTTGATGCCTGCAAAGAAGCTGGTGTTACCTTTATG
+GCGGGTCACGTTATGAACTTTTTTCACGGGGTTCGCCACGCTAAAGCGCTCATCAAAGCC
+GGTGAAATCGGTGAAGTTACACAAGTTCACACTAAACGTAATGGTTTTGAAGACGTGCAG
+GATGAGATCTCATGGAAGAAGATTCGCGCAAAGTCAGGTGGGCATCTGTACCATCACATT
+CACGAGCTAGATTGTACACTGTTCATCATGGATGAAACCCCATCCCTGGTTTCAATGGCG
+GCGGGGAATGTTGCGCACAAAGGTGAAAAATTTGGTGATGAAGATGATGTTGTCCTAATC
+ACCCTTGAGTTTGAAAGCGGTCGTTTCGCGACACTTCAGTGGGGATCATCGTTCCACTAC
+CCTGAGCACTATGTATTAATTGAGGGCACGACAGGTGCAATTCTCATTGATATGCAAAAC
+ACGGCTGGTTATCTAATAAAAGCGGGCAAAAAAACACACTTTCTTGTGCATGAAAGCCAG
+GCGGAGGATGATGATCGTCGCAACGGTAACATATCCAGCGAGATGGATGGCGCAATCGCT
+TATGGTAAACCCGGTAAACGTACGCCGATGTGGCTCTCATCAATTATGAAACTGGAGATG
+CAGTACTTGCATGATGTGATAAACGGTCTGGAGCCAGGCGAGGAGTTTGCTAAATTGCTA
+ACGGGAGAAGCGGCGACAAATGCCATTGCTACCGCTGATGCTGCGACGCTTTCTTCAAAC
+GAGGGGCGCAAAGTTAAACTCACTGAAATTCTTGGCATGGAGATAATTTTTTATCACCCG
+ACATTTAACGCCGCCTGGTGGGTAAATGCGCTGGAGAAGGCTCTCCCACATGCGCGCGTT
+CGTGAATGGAAGGTCGGTGATAACAACCCCGCAGACTATGCGCTTGTATGGCAGCCCCCG
+GTTGAAATGCTGGCCGGAAGACGCTTAAAAGCCGTCTTTGTGCTGGGCGCGGGGGTGGAT
+GCAATTCTGAGTAAATTAAATGCGCATCCGGAAATGCTGGACGCCTCCATTCCTCTATTC
+CGTCTGGAAGATACCGGAATGGGCCTGCAAATGCAGGAGTATGCCGCCAGCCAGGTATTA
+CACTGGTTCCGTCGTTTCGATGATTATCAGGCGCTGAAAAATCAGGCGCTATGGAAACCG
+TTGCCGGAATATACCCGCGAAGAGTTTAGCGTCGGTATCATAGGCGCAGGGGTACTGGGC
+GCAAAAGTGGCAGAAAGTCTACAGGCGTGGGGGTTCCCGTTACGTTGCTGGAGTCGTAGC
+CGCAAATCCTGGCCTGGCGTGGAAAGTTATGTAGGGCGTGAAGAACTGCGCGCTTTCCTG
+AACCAGACGCGGGTGCTGATTAATCTGCTGCCGAATACGGCCCAAACGGTAGGAATTATT
+AATAGCGAATTGTTGGATCAATTGCCGGATGGCGCTTACGTGCTGAATCTCGCGCGCGGC
+GTTCATGTTCAGGAGGCGGATCTGCTGGCTGCGCTTGATAGCGGTAAGCTAAAAGGCGCG
+ATGTTGGATGTCTTTAGCCAGGAACCGTTACCGCAGGAAAGTCCATTATGGCGCCATCCG
+CGAGTCGCCATGACGCCGCACATTGCGGCAGTCACCCGTCCGGCGGAAGCCATCGATTAT
+ATTAGCCGCACCATTACCCAGCTGGAGAAGGGAGAGCCGGTGACGGGGCAGGTGGATCGG
+GCGAGAGGATAT---ATGATGCGCGCCATGAACATACTTCTTTCTATTGCTATCACTACG
+GGCATCCTTTCTGGAATATGGGGATGGGTGGCCGTCTCCCTGGGGTTACTAAGCTGGGCC
+GGTTTTTTAGGCTGTACGGCTTATTTCGCCTGTCCGCAGGGCGGCTTTAAGGGATTGTTG
+ATTTCCGCCTGTACGCTGTTAAGCGGTATGGTGTGGGCGCTGGTCATTATTCACGGTAGC
+GCGTTGGCGCCGCATCTGGAAATTGTCAGTTACGTGTTGACGGGGATCGTGGCATTCCTG
+ATGTGTATCCAGGCAAAGCAGCTATTGCTTTCTTTTGTTCCGGGAACATTTATCGGCGCC
+TGCGCGACATTTGCAGGGCAGGGTGACTGGCGGTTGGTATTACCGTCGCTGGCGCTGGGG
+CTAATCTTTGGCTATGCCATGAAAAATAGTGGGCTATGGCTGGCATCACGCCGCGAGCAA
+CATTCAGCGAATACGGCGGTCACAAAAATGAAACGCTATCTGACCTGGATTGTAGCAGCA
+GAGTTACTGTTCGCTACCGGAAACCTGCATGCCAATGAAGTTGAAGTCGAGGTTCCCGGA
+TTGTTAACCGACCATACCGTCTCTTCGATAGGACATGAATTCTATCGTGCATTCAGCGAC
+AAATGGGAAAGCGAATACACCGGCAATCTGACCATTAATGAAAGACCCAGTGCGCGTTGG
+GGAAGCTGGATCACCATAACGGTAAATCAGGACGTTATTTTCCAGACCTTTTTATTTCCA
+ATGAAAAGAGACTTCGAGAAAACCGTCGTCTTCGCATTAGCGCAAACAGAGGAAGCATTA
+AATCGCCGACAAATAGATCAAACGCTATTAAGTACGAGTGATTTAGCGCGTGATGAATTC
+ATGTCCGTAATCAAGAAAAATATCCCTGCCATAGGCCTGTGTATCTGCGCTTTTTTTATC
+CATTCTGCGGTAGGGCAACAAACGGTACAGGGCGGCGTTATCCATTTTCGCGGCGCGATT
+GTTGAGCCACTGTGCGATATTTCTACTCACGCCGAAAATATTGATTTAACCTGCCTACGC
+GAAGGTAAAAAGCAAATGCACCGGATAGACCTTCGGCAGGCATCTGGATTACCGCAGGAT
+ATTCAGTCCATTGCGACGGTACGGCTGCATTATCTCGATGCGCAAAAAAGCCTGGCGGTG
+ATGAATATTGAGTACCGTATGACATCACGTCTTCAGGTCATACAGGGTGATATCACTCAA
+CTTAGCGTCGATGCGATTGTGAATGCCGCTAACGCATCATTAATGGGCGGCGGTGGCGTA
+GACGGCGCAATTCATCGCGCGGCGGGGCCGGCATTGCTGGACGCCTGTAAACTCATCCGT
+CAGCAACAGGGCGAATGTCAGACGGGACATGCGGTTATCACGCCTGCTGGCAAGCTTTCG
+GCAAAGGCGGTTATTCACACAGTGGGGCCCGTCTGGCGAGGCGGCGAACACCAGGAAGCT
+GAGCTACTCGAAGAGGCATACCGGAATTGTTTGCTGCTTGCCGAGGCGAATCACTTTCGT
+TCCATCGCTTTTCCGGCAATCAGTACCGGCGTTTATGGCTATCCACGCGCCCAGGCCGCT
+GAAGTCGCCGTCAGGACGGTTTCAGATTTTATTACCCGTTACGCTCTGCCTGAACAGGTA
+TACTTTGTCTGTTATGATGAAGAAACTGCCCGGCTTTACGCAAGATTACTTACTCAGCAA
+GGCGACGACCCTGCCATGAAGAAACTGCCCGGCTTTACGCAAGATTACTTACTCAGCAAG
+GCGACGACCCTGCCTGATAAAACACGCCTGGAGCGTGCCGTTGAACCGCTATGCGCGCGC
+CATCCCGGAGAGTGCGGCATTCTTGCGCTGGATAACAGTCTGGACGCTTTTGCCGCCCGC
+TACCGCCTGACCGAAATGGCGGCGCGGACGCTGGATGTGCAGTATTATATTTGGGAAGAC
+GATATGTCCGGGCGGCTGCTCTTTTCGGTTCTGCTGTCGGCGGCGAAGCGCGGCGTTCAT
+GTTCGTCTGCTGCTGGATGATAACAATACGCCTGGTCTGGATGATACGTTGCGCTTGCTG
+GATAGCCATCCTAATATCGAAGTTCGTCTGTTTAATCCTTTCTCTTTTCGTACGCTACGC
+GCGCTGGGATATTTGACGGATTTTGCGCGGCTGAATCGGCGGATGCACAATAAAAGTTAC
+ACTGCCGACGGCGTAGTGACGCTGGTCGGTGGGCGCAACATCGGCGATGCCTATTTCGGC
+GCTGGCGAGGAGCCGCTATTTTCCGATCTGGACGTGATGGCCATTGGCCCGGTGGTCAAT
+GATGTCGCCAATGATTTTGAACGTTACTGGCGCTGTAGTTCAGTGTCGACATTGCAGCAA
+GTATTATCCCTTTCTGAGCAGGAACTGACGCAGCGTATCGAACTTCCCGAATCCTGGTAT
+AACGATGAGATCACCCGCCGTTATCTGCATAAGCTGGAAACCAGCCAGTTTATGGCGGAT
+CTCGATCGCGGAACGTTGCCGCTGATTTGGGCAAAAACACGCTTGCTTAGCGATGACCCT
+TCTAAAGGCGAGGGGAAGGCGCAGCGCCATTCGCTTCTTCCGCAGCGATTATTTGACGTG
+ATGGGGTCGCCGACGGAGCGTATCGACATTATTTCCGCTTACTTTGTCCCTACGCGCGCA
+GGCGTGGCGCAGTTGCTTAATCTGGTCAGGAAAGGTGTGAAGATCGCCATCTTAACTAAC
+TCTCTGGCGGCCAACGATGTGGCGGTCGTTCACGCAGGGTACGCGCGCTGGCGCAAGAAA
+TTACTGCGCTATGGCGTGGAGCTCTACGAACTGAAACCGACCCGCGAACATGAAACCGCC
+GTACATGATCGCGGACTCACCGGGAACTCAGGTTCCAGCTTACATGCTAAAACGTTCAGT
+ATTGATGGTAGTAAGGTGTTTATCGGGTCGCTTAATTTTGATCCCCGTTCAACGCTTTTA
+AATACCGAAATGGGCTTTGTCATTGAAAGTGAAACGCTGGCGACGCTTATTCATAAGCGT
+TTTACGCAGAGCCAACGCGATGCGGCCTGGCAACTGCGGCTGGATCGCTGGGGACGAATT
+AACTGGATCGATCGTCAGCAAGAAGAGGAAAAGGTGTTAAAGAAAGAACCCGCTACGCGT
+TTCTGGCAGCGAGTTCTGGTACGGTTGGCGGCAATTTTACCTGTGGAATGGTTGCTGATG
+AGCTCTGTACCCGCGCCGCGTGAATATTTTCTTGACTCTATCCGCGCATGGCTGATGTTG
+TTAGGGATTCCCTTTCATATCTCGTTGATCTATTCCACTCACAGTTGGCATGTCAATAGC
+GCCGCGCCATCGTGGTGGCTAACCCTGTTTAACGATTTTATCCACGCTTTTCGTATGCAG
+GTGTTTTTTGTTATTTCTGGTTATTTTTCGTACATGTTATTTTTACGTTATCCATTAAAA
+CACTGGTGGAAAGTACGGGTAGAACGTGTGGGTATTCCCATGCTTACCGCAATCCCTTTG
+CTTACCTTGCCGCAATTTATCCTGTTGCAATATGTCAAAGAGAAAACAGAGAACTGGCCT
+ACACTCTCTGCCTATGAAAAATATAATACGTTAGCGTGGGAACTCATTTCACATCTGTGG
+TTTTTACTGGTGCTGGTGATATTAACCACCGTCAGCATCGGGATTTTTACCTGGTTCCAA
+AAAAGGCAGGAAACAAGCAAGCCTCGTCCCGCCGCTATTTCGCTGGCCAAACTTTCGCTT
+ATTTTTTTCCTGCTGGGGGTGGCGTACGCTGCTATCAGGCGCATTATATTCATCGTATAT
+CCGGCAATCCTCAGTGACGGCATGTTCAATTTTATTGTGATGCAAACGCTATTTTATGTG
+CCGTTTTTTATTCTCGGCGCGTTGGCCTTCATTCACCCCGATCTGAAAGCGCGCTTCACC
+ACGCCCTCACGCGGATGCACTTTAGGCGCTGCCGTTGCTTTTATCGCGTATCTGCTGAAT
+CAACGTTATGGGAGCGGCGACGCCTGGATGTACGAAACCGAATCCGTGATTACGATGGTA
+ATGGGGCTATGGATGGTGAACGTGGTATTTTCACTGGGGCATCGCTTGTTAAACTTTCAG
+TCCGCGCGTGTCACCTATTTCGTGAATGCTTCGCTGTTTATTTATCTGGTGCATCATCCC
+TTAACGCTTTTCTTTGGCGCGTATATTACACCGCATATCTCCTCCAACCTGATCGGGTTC
+TTGTGCGGGCTGATATTTGTTATGGGTATTGCGTTAATTCTGTATGAAATTCATTTACGC
+ATCCCGCTCCTGAAATTTCTCTTTTCAGGTAAACCGCCGGTAAAACAAGAAAGCCGCGCC
+GCGATCGGGATGAAACATAAACGACAAATGATGAAAATGCGTTGGTTGGGCGCAGCTATT
+ATGTTAACGCTCTACGCATCATCGAGCTGGGCGTTCAGTATTGATGACGTGGCAAAACAA
+GCTCAATCTTTAGCCGGGAAAGGCTATGAGGCGCCTAAAAGCAACTTGCCCTCCGTTTTC
+CGCGACATGAAATATGCGGATTATCAGCAGATCCAGTTTAACAGCGATAAAGCCTACTGG
+AACAACTTAAAGACCCCTTTTAAGCTCGAATTTTACCATCAGGGGATGTACTTCGATACG
+CCGGTCAAGATTAACGAAGTGACGGCGACGACGGTCAAAAGAATCAAATACAGCCCGGAT
+TACTTCAATTTTGGCAATGTTCAGCACGATAAAGACACGGTAAAAGATTTAGGCTTCGCC
+GGGTTCAAAGTCCTGTACCCCATTAACAGTAAAGATAAGAACGACGAAATCGTCAGTATG
+CTTGGCGCCAGCTATTTCCGCGTTATCGGCGCAGGCCAGGTGTATGGCTTATCTGCGCGC
+GGCCTGGCGATTGATACCGCCTTACCATCTGGTGAAGAGTTTCCCCGCTTTCGCGAGTTC
+TGGATTGAGCGTCCAAAACCCACCGATAAGCGTTTGACCGTCTATGCATTACTGGATTCT
+CCGCGCGCGACCGGCGCTTACCGTTTTGTGATCATTCCTGGCCGCGATACCGTGGTGGAC
+GTGCAGTCAAAAGTCTATCTGCGCGATAAGGTGGGCAAGCTGGGCGTTGCGCCATTAACC
+AGTATGTTCCTGTTTGGGCCAAACCAGCCGTCGCCGACGACCAACTATCGTCCGGAATTG
+CATGACTCGAACGGCTTATCCATTCATGCGGGTAATGGCGAGTGGATTTGGCGTCCGCTG
+AACAATCCAAAACACCTCGCTGTGAGCAGCTATGCGATGGAAAACCCTCAGGGATTCGGC
+CTGTTGCAGCGTGGTCGCGAGTTCTCGCGCTTTGAAGATTTAGACGATCGCTATGACCTG
+CGTCCAAGCGCCTGGATTACCCCGAAAGGCGACTGGGGCAAAGGTAAGGTTGAACTGGTT
+GAAATTCCGACCAATGATGAAACCAACGATAACATCGTCGCTTACTGGACTCCGGATCAA
+CTGCCGGAACCGGGTAAAGAGATGAACTTCAAGTACACTCTGACCTTCAGCCGCGATGAA
+GATAAACTTCATGCGCCGGATAATGCCTGGGTGCTGCAAACACGCCGCTCAACGGGCGAC
+GTTAAACAGTCGAATCTGATTCGCCAGCCCGACGGCACTATTGCCTTTGTGGTGGATTTC
+GTTGGCGCCGACATGAAAAAACTGCCGCCGGATACGCCCGTCGCTGCACAAACCAGCATT
+GGCGATAACGGTGAAATCGTTGACAGTAATGTACGCTATAACCCAGTCACTAAAGGCTGG
+CGTTTAATGCTGCGCGTGAAAGTCAAAGACGCGAAGAAAACCACGGAAATGCGTGCCGCA
+TTGGTGAATGCCGATCAGACGCTAAGTGAAACCTGGAGCTACCAGTTACCTGCCAATGAA
+ATGAATAAAACAACTGAGTATATTGACGCACTGCTGCTTTCTGAACGTGAGAAAGCGGCA
+TTGCCGAAAACTGACATCCGCGCCGTGCATCAGGCGCTGGATGCCGAGCATCGGACTTAC
+TCGCGAGAAGACGATTCACCGCAGGGTTCCGTAAAAGCCCGCCTTGAACACGCCTGGCCG
+GATTCATTGGCGAAGGGGCAGTTAATTAAAGATGATGAAGGGCGCGATCAGTTGCAGGCT
+ATGCCAAAAGCGACGCGCTCTTCGATGTTTCCTGATCCCTGGCGAACCAACCCGGTTGGC
+CGTTTCTGGGATCGCCTGCGTGGGCGGGATGTAACGCCGCGCTATGTTTCTCGTCTGACA
+AAAGAAGAGCAGGCGAGTGAGCAAAAATGGCGTACCGTCGGCACTATACGCCGCTATATT
+TTGTTAATTTTGACTCTGGCGCAAACCGTCGTCGCGACCTGGTATATGAAGACCATTCTG
+CCCTATCAGGGATGGGCGCTCATCAATCCTATGGATATGGTGGGGCAGGATATTTGGGTC
+TCCTTTATGCAGCTCCTGCCCTACATGCTGCAAACCGGTATCCTGATTTTGTTTGCCGTG
+CTGTTCTGCTGGGTGTCTGCCGGATTCTGGACGGCGCTGATGGGCTTCCTGCAACTGCTT
+ATCGGGCGCGATAAGTACAGTATCTCCGCGTCTACGGTTGGCGATGAGCCCCTCAATCCG
+GAACACCAGACGGCGCTGATCATGCCTATCTGTAATGAAGACGTTAGCCGCGTTTTCGCC
+GGTCTGCGCGCGACCTGGGAGTCCGTTAAAGCCACAGGCAACGCCGCGCATTTTGACGTC
+TATATCCTTAGCGATAGTTATAACCCGGATATCTGCGTGGCGGAGCAAAAGGCGTGGATG
+GAGCTCATCGCGGAAGTGCAGGGCGAAGGCCAAATTTTTTACCGTCGCCGCCGCCGCCGT
+ATGAAACGCAAAAGCGGCAATATTGACGATTTTTGCCGCCGCTGGGGCAATCAGTACAGC
+TATATGGTGGTGCTGGACGCGGACTCAGTGATGAGCGGCGAGTGTCTGAGCGGGCTGGTG
+CGCCTGATGGAAGCGAACCCTAACGCCGGGATTATCCAGTCTTCGCCGAAAGCGTCGGGG
+ATGGATACTCTGTATGCCCGCTGCCAACAGTTCGCGACCCGTGTTTATGGACCGCTGTTT
+ACCGCCGGGCTGCACTTCTGGCAGTTGGGGGAGTCGCACTACTGGGGGCACAATGCCATT
+ATCCGCGTGAAGCCGTTTATCGAGCACTGCGCTCTGGCGCCGCTGCCGGGAGAAGGTTCG
+TTCGCCGGATCGATTCTTTCCCACGACTTTGTGGAGGCGGCGCTAATGCGTCGGGCAGGG
+TGGGGCGTCTGGATTGCCTACGATCTCCCCGGCTCCTATGAAGAGCTGCCGCCAAACCTG
+CTGGATGAGCTTAAACGCGACCGCCGCTGGTGTCACGGCAACCTGATGAACTTTCGTCTG
+TTCCTGGTGAAAGGAATGCACCCGGTGCATCGCGCCGTGTTCCTGACCGGGGTAATGTCA
+TACCTGTCCGCGCCGTTATGGTTTATGTTCCTCGCGCTTTCTACCGCGCTGCAGGTCGTT
+CATGCGTTAACAGAGCCGCAATATTTCCTTCAGCCGCGCCAGCTTTTTCCGGTCTGGCCG
+CAGTGGCGTCCGGAACTGGCAATCGCGCTGTTTGCGTCAACGATGGTGCTGCTGTTCCTG
+CCGAAGCTGCTCAGTATTATGCTGATCTGGTGTAAAGGCACCAAAGAGTATGGCGGTTTC
+TGGCGCGTTACGCTGTCGCTATTGCTGGAAGTGCTGTTCTCCGTGTTGCTGGCGCCGGTG
+CGTATGCTGTTTCATACCGTGTTTGTGGTCAGCGCGTTCCTCGGCTGGGAAGTGGTCTGG
+AACTCACCGCAACGCGACGATGATTCTACGCCGTGGGGAGAAGCCTTTATGCGTCACGGC
+TCTCAACTGCTGCTGGGGCTGGTCTGGGCGGTGGGTATGGCGTGGCTGGATTTACGCTTT
+CTGTTCTGGCTGGCGCCGATTGTCTTTTCGCTGATTCTGTCGCCATTTGTTTCGGTGATC
+TCCAGTCGTTCAACGGTAGGATTACGCACCAAACGCTGGAAGCTGTTCCTGATCCCGGAA
+GAGTATTCGCCGCCTCAGGTGTTGGTCGATACCGATAAATATCTGGAGATGAATCGCCGC
+CGTATTCTGGACGATGGCTTTATGCATGCGGTATTTAACCCGTCGCTTAATGCGCTGGCG
+ACCGCGATGGCCACCGCGCGTCACCGCGCCAGTAAGGTGCTGGAAATAGCCCGCGATCGT
+CATGTGGAGCAGGCGCTAAACGAAACGCCGGAGAAACTGAACCGCGATCGGCGTCTGGTT
+TTGCTCAGCGATCCGGTGACGATGGCGCGTTTACACTATCGGGTCTGGAATGCGCCAGAG
+AGATACTCTTCCTGGGTAAACCATTATCAGTCTCTCGTCCTGAATCCGCAGGCGTTGCAG
+GGACGAACATCGTCAGCGGGAGTGCGTATATTCGCGGTGAGCATAATGGTGATTACCCTG
+AGCGGCTGCGGCAGTATTATCAGCAGAACGATCCCCGGACAAGGACACGGCAACCAGTAT
+TACCCTGGCGTGCAGTGGGATATGCGTGATTCCGCATGGCGCTATATCACTATCCTCGAT
+CTGCCCTTCTCACTGATCTTCGATACACTGCTACTGCCGCTCGATATTCACCACGGGCCT
+TATGAGATGAAAAAAAACCTGCTGGGATTCACCCTCGCATCCTTGTTATTCACGACCGGT
+TCCGCCGTGGCGGCGGAGTATAAAATTGATAAAGAAGGCCAACATGCGTTCGTCAATTTC
+CGCATCCAGCATCTGGGCTACAGCTGGCTATACGGCACCTTTAAAGATTTCGACGGCACG
+TTCACTTTTGACGAAAAAAATCCGTCAGCAGACAAAGTGAATGTGACCATTAACACCAAT
+AGCGTCGACACTAACCATGCCGAACGTGACAAACACCTGCGTAGCGCGGAGTTTCTTAAT
+GTTGCGAAATTCCCGCAGGCAACCTTCACCTCTACCAGCGTGAAAAAAGAGGGCGATGAA
+CTGGATATTACCGGCAATCTGACGCTCAATGGCGTGACTAAACCGGTGACGCTGGAAGCG
+AAGCTGATGGGCCAGGGCGACGATCCGTGGGGCGGTAAGCGCGCGGGCTTTGAGGCCGAA
+GGAAAAATTAAGCTGAAAGATTTCAATATAACTACCGATCTCGGCCCAGCCTCACAAGAG
+GTGGAGCTTATCATCTCAGTAGAAGGCGTTCAGCAGAAGATGTTACTGATGATGGCGCTG
+ATCGTGCGTATTATCTGGCGGCTTTATTCTCCGCCGCCCGTTGCGTTGACCAGCTATTCC
+CGTTTAACGCGCATTGGCGCCGCCGCGGGTCATATCCTTCTGTATCTCCTGCTCTTTGCG
+ATAATCATTAGCGGCTACCTGATTTCCACCGCCGACGGTAAACCGATTAGCGTCTTTGGC
+TGGTTTGAGATTCCGGCCACGCTTACGGACGCGGGCGCGCAGGCTGACATCGCCGGAACA
+CTGCATCTGTGGTTTGCCTGGTCGCTGGTCATTATCTCGCTCTCGCATGGGGTTATGGCG
+CTAAAACACCATTTCATCGATAAAGACGACACACTGAAACGTATGACAGGAATGTCGTCA
+TCTGACTATGGAGCTCAAAAAATGAAATACGACCTTATTATTATCGGCAGCGGTTCGGTT
+GGCGCCGCCGCTGGTTATTACGCCACCCGCGCCGGGCTAAAGGTCCTGATGACCGATGCG
+CATATGCCGCCTTATCAACAGGGCAGCCACCACGGCGATACCCGTCTTATCCGCCACGCT
+TATGGTGAAGGCGAAAAATATGTCCCGCTGGTGCTTCGCGCCCAGACGCTTTGGGATGAG
+CTCTCCACACACAATGAAGAGCCTATTTTTGTCCGCTCCGGCGTCGTCAACCTCGGCCCG
+GCCGATTCCGCTTTCTTAGCCAACGTCGCACGAAGCGCGCAACAGTGGCAATTGAACGTC
+GAGCGCCTGGACGCGACGGCCCTCATGACGCGCTGGCCGGAAATTCGCGTGCCCGATAAT
+TATATCGGGCTGTTTGAAGCTGACTCCGGTTTCCTGCGCAGCGAATTAGCCATTACCACA
+TGGCTTCGTCTGGCCCGAGAGGCAGGCTGCGCACAGCTATTCAACAGCCCGGTAAGCCAT
+ATTCACCATGATGATAACGGTGTGACGATAGAGACGAGTGAAGGCTGCTACCACGCCAGC
+AAAGCGCTGATTAGCGCGGGCACCTGGGTCAAAACGCTGGTACCGGAGCTGCCCGTTCAG
+CCCGTACGTAAAGTTTTTGCCTGGTTTAAGGCGGATGGACGTTACAGCACTAAAAACCGC
+TTTCCGGCCTTTACCGGCGAAATGCCCAACGGCGATCACTATTACGGTTTCCCGGCGGAG
+AACGACGAGTTAAAAATCGGCAAACACAATGGCGGGCAGCGAATACAGGCACCGGAAGAG
+CGCAAGCCCTTTGCCGCCGTTGCCAGCGATGGCGCGGAAGCATTTCCTTTCCTGCGTAAC
+GTACTGCCGGGTATCGGCGGTTGTTTACATGGGGCGGCATGTACCTATGATAATTCGCCG
+GACGAGGATTTTATTATCGATACGCTGCCTGGCCATGAGAATACGCTTGTCATCACTGGA
+CTCAGCGGACATGGTTTTAAATTCGCCCCGGTGTTAGGAGAAATCGCTGCGGATTTTGCG
+TTGGGAAAAACGCCCTCCTTTGATCTGACGCCGTTCCGGCTTTCCCGTTTTAGCCAAATG
+GAAAAGAATAATGAAGTCATTCAGACCCATCCGCTTGTAGGATGGGACATCAGCACCGTC
+GATAGCTATGATGCGCTGATGCTGCGTTTACACTACCAGACCCCAAATCGTCCGGAACCG
+GAAGGGACTGAAGTTGGTCAAACGCTCTGGTTAACGACAGATGTAGCCAGGCAATTTATT
+TCAATATTAGAAGCCGGCATCGCCAAAATAGAATCAGGCGATTACCAGGAAAACGAGTAT
+CGTCACCAT
+>22222_2#22
+ATGCGTATCAGTACCCAGATGATGTACGAACAAAATATGAGCGGCATCACTAATTCTCAG
+GCCGAATGGATGAAGCTGGGCGAGCAGATGTCTACCGGTAAGCGCGTTACCAACCCATCT
+GACGATCCGATCGCCGCGTCGCAGGCGGTAGTACTCTTTCAGGCGCAGGCGCAGAATAGC
+CAGTACGCCCTGGCGCGTACGTTTGCCACCCAAAAAGTGTCGCTGGAAGAAAGCGTACTC
+AGTCAGGTGACGACGGCGATTCAAACCGCGCAGGAAAAAATCGTCTATGCCGGAAACGGC
+ACGTTAAGCGACGATGACCGCGCGTCGCTGGCGACGGATTTACAGGGGATCCGCGATCAG
+CTGATGAACCTGGCAAACAGCACTGACGGCAATGGTCGCTATATCTTTGCCGGGTATAAA
+ACGGAAGCGGCGCCATTCGACCAGGCGACAGGTGGTTATCATGGCGGCGAGAAAAGTGTT
+ACCCAGCAGGTGGATTCCGCACGCACGATGGTAATTGGCCATACGGGAGCGCAAATTTTT
+AATAGCATCACCAGCAATGCGGTGCCGGAACCGGATGGCTCGGACTCCGAAAAGAATCTG
+TTTGTCATGCTCGATACGGCAATTGCCGCGCTCAAGACCCCGGTGGAAGGCAATGACGTG
+GAAAAAGAAAAAGCCGCTGCCGCCATTGATAAAACCAATCGCGGCTTAAAAAATTCGCTT
+AATAACGTCCTGACCGTTCGTGCGGAACTGGGAACGCAACTGAGCGAACTCAGTACGCTG
+GATTCACTGGGAAGCGACCGTGCGCTGGGACAGAAGCTACAGATGAGCAACCTGGTAGAT
+GTGGACTGGAACTCGGTCATTTCCTCCTACGTCATGCAACAGGCGGCATTACAGGCGTCC
+TATAAAACGTTTACCGACATGCAGGGAATGTCGCTTTTCCAGTTGAACCGGATGTCCAGC
+TTGATTAATCACGCCATGAGCGGACTTAACGCCGCGCAGGCCGCGTTAAATACGGTCAGT
+AATAACATCAACAATTATAACGTTGCGGGTTATACCCGGCAGACAACTATTCTGGCGCAG
+GCAAACAGTACGTTAGGGGCTGGCGGCTGGATAGGTAATGGCGTTTACGTTTCAGGCGTA
+CAGCGCGAATATGATGCGTTTATCACTAATCAGCTACGCGGCGCGCAAAACCAGAGCAGC
+GGCTTAACCACGCGCTATGAACAAATGTCGAAAATCGACAACCTGCTGGCCGATAAATCC
+AGCTCACTGTCTGGCTCGCTGCAGAGTTTTTTTACCAGCCTGCAAACGTTAGTCAGTAAT
+GCGGAAGATCCTGCGGCGCGTCAGGCGCTGATTGGTAAAGCGGAAGGGCTGGTAAACCAG
+TTCAAAACCACCGATCAGTATCTGCGCGATCAGGATAAACAGGTCAATATCGCGATTGGC
+TCCAGCGTGGCGCAAATCAACAATTACGCGAAGCAGATAGCTAACCTGAACGATCAAATC
+TCCCGTATGACGGGCGTAGGCGCGGGCGCATCGCCGAACGACCTGCTCGATCAACGTGAT
+CAGTTGGTTAGCGAGCTTAACAAGATCGTTGGCGTCGAGGTGAGTGTACAGGACGGCGGC
+ACCTATAACCTGACGATGGCCAATGGCTATACGCTGGTGCAGGGGTCGACGGCGCGTCAG
+TTGGCGGCGGTTCCCTCCAGCGCCGACCCGACGCGAACGACTGTCGCTTATGTCGATGAG
+GCCGCCGGTAACATCGAAATTCCGGAAAAGTTGCTGAACACCGGTTCGCTCGGCGGGCTA
+CTGACGTTCCGTTCTCAGGATCTGGATCAGACTCGTAATACGCTGGGCCAGTTGGCGTTG
+GCGTTTGCCGATGCGTTTAACGCGCAGCATACCAAAGGTTATGACGCCGACGGCAATAAA
+GGGAAAGACTTCTTTAGCATTGGCTCGCCGGTGGTATATAGCAACAGTAATAATGCCGAT
+AAAACGGTATCGCTAACCGCTAAGGTGGTCGACAGCACGAAGGTTCAGGCGACGGATTAT
+AAGATTGTTTTTGACGGTACAGACTGGCAGGTTACTCGCACTGCGGATAACACCACCTTC
+ACGGCAACAAAAGATGCTGACGGAAAACTGGAGATTGACGGTCTGAAAGTGACGGTAGGG
+ACTGGCGCACAGAAAAACGACAGTTTTCTTCTCAAGCCGGTCAGCAATGCTATCGTCGAC
+ATGAACGTTAAAGTGACAAATGAAGCCGAGATTGCGATGGCGTCTGAGTCAAAACTCGAT
+CCTGATGTGGATACCGGCGACAGCGATAACCGCAATGGTCAGGCATTGCTGGACTTACAA
+AACAGCAATGTAGTGGGCGGCAACAAAACCTTTAACGATGCTTACGCCACGTTGGTCAGC
+GATGTGGGTAACAAAACGTCAACGCTGAAAACCAGCAGCACCACGCAGGCGAATGTGGTT
+AAACAGCTTTATAAACAGCAACAGTCGGTTTCCGGCGTTAACCTCGACGAAGAGTACGGC
+AATTTGCAGCGTTATCAGCAGTATTATCTGGCGAATGCGCAAGTATTGCAGACCGCGAAT
+GCGCTGTTTGATGCGTTATTGAATATTCGCATGATCGGAGACGGTAAATTGCTGGCCAGC
+GCGGCCTGGGATGCGCAATCTCTGAACGAACTGAAAGCGAAAGCGGGCCAGGACCCGGCG
+GCGAATATCCGTCCTGTGGCCCGTCAGGTGGAAGGGATGTTTGTGCAGATGATGCTGAAA
+AGTATGCGCGAGGCTTTACCCAAAGATGGTTTATTCAGCAGCGATCAGACGCGTCTGTAT
+ACCAGCATGTATGACCAGCAGATCGCCCAGCAGATGACCGCCGGTAAGGGATTGGGGCTG
+GCGGATATGATGGTTAAACAGATGACGGGCGGGCAGACGATGCCTGCAGATGATGCGCCG
+CAAGTACCGCTTAAATTCTCCCTGGAGACGGTAAACAGCTATCAAAATCAGGCGCTGACC
+CAACTGGTGCGCAAAGCCATACCGAAAACGCCGGACAGCAGCGATGCGCCGCTCTCCGGC
+GACAGTAAAGACTTTCTGGCCCGGCTTTCGCTCCCGGCGAGGCTGGCCAGCGAACAAAGC
+GGGGTGCCGCATCATCTGATTCTGGCGCAGGCGGCGCTGGAGTCCGGCTGGGGGCAGCGG
+CAAATCCTGCGGGAGAATGGCGAACCCAGCTATAACGTATTTGGCGTGAAAGCGACCGCC
+AGTTGGAAAGGGCCGGTGACGGAAATCACCACCACTGAATACGAAAATGGCGAAGCGAAA
+AAAGTGAAAGCGAAATTCCGCGTCTATAGCTCGTATCTGGAGGCGTTATCGGATTATGTC
+GCGCTGTTAACGCGTAACCCACGCTACGCTGCCGTGACCACTGCCGCCACGGCAGAGCAG
+GGCGCAGTGGCTCTGCAAAACGCCGGATACGCCACTGACCCGAATTACGCGCGTAAATTG
+GCCAGCATGATTCAGCAGTTGAAAGCGATGAGTGAAAAGGTCAGCAAAACCTACAGCGCG
+AATCTCGACAATCTCTTTGTGTTTAAAGCTCTTGCAGGAATCGTTCTGGCACTGGTTGCC
+ACTCTGGCGCACGCCGAGCGTATCCGGGATCTGACCAGTGTCCAGGGAGTACGGGAAAAC
+TCGCTGATCGGCTACGGGCTGGTGGTCGGGCTGGACGGTACGGGCGACCAGACGACCCAG
+ACGCCATTTACCACCCAGACGCTGAATAACATGCTGTCACAACTGGGGATTACGGTCCCC
+ACCGGCACCAATATGCAGTTGAAAAACGTGGCGGCGGTGATGGTGACGGCGTCGTATCCG
+CCTTTTGCGCGACAGGGACAAACGATCGATGTCGTCGTTTCCTCAATGGGGAACGCTAAA
+AGTCTGCGTGGCGGGACGTTATTAATGACGCCGTTAAAAGGGGTGGACAGCCAGGTGTAT
+GCTCTGGCGCAGGGCAATATTCTGGTCGGCGGCGCGGGCGCTTCCGCAGGCGGCAGTAGC
+GTGCAGGTTAACCAGCTTAATGGCGGGCGCATCACTAATGGCGCGATTATCGAACGCGAG
+TTGCCGACTCAGTTCGGCGCTGGCAACACCATTAATCTGCAATTGAACGACGAAGATTTT
+ACGATGGCGCAGCAAATTACCGACGCCATCAACCGCGCCCGCGGTTACGGCAGCGCCACT
+GCGCTTGATGCGCGAACGGTACAGGTACGCGTGCCCAGCGGCAACAGCTCGCAGGTGCGT
+TTTCTGGCGGACATTCAAAATATGGAAGTCAACGTGACGCCGCAGGATGCAAAAGTCGTG
+ATCAACTCGCGTACCGGTTCGGTGGTCATGAATCGGGAAGTCACGCTGGATAGCTGCGCT
+GTGGCGCAGGGCAATTTGTCAGTGACAGTCAATCGCCAACTCAACGTCAACCAGCCGAAT
+ACGCCATTTGGCGGCGGGCAGACCGTGGTGACGCCACAGACTCAGATAGATTTGCGTCAG
+AGCGGCGGATCGCTACAGAGCGTGCGTTCCAGCGCCAATCTGAACAGCGTAGTGCGCGCG
+CTGAATGCGCTTGGCGCGACGCCGATGGATCTGATGTCGATTTTGCAGTCCATGCAGAGC
+GCGGGCTGTCTACGCGCCAAACTGGAAATCATCATGGCCCTGATGGTCGCGACGCTGACA
+GGATGCGCCTGGATACCCGCTAAACCGCTCGTGCAGGGGGCGACCACGGCGCAGCCGATA
+CCTGGCCCGGTACCGGTGGCGAATGGCTCCATATTTCAGTCTGCGCAGCCGATTAATTAT
+GGCTATCAGCCGCTTTTTGAAGATCGTCGACCGCGTAATATCGGCGATACGCTCACGATT
+GTGTTACAGGAAAACGTCAGCGCCAGTAAAAGCTCGTCGGCAAATGCCAGCCGCGACGGC
+AAAACCAGCTTTGGTTTTGATACGGTACCGCGTTATCTGCAGGGATTATTCGGTAATTCC
+CGCGCGGATATGGAGGCCTCCGGCGGCAACTCTTTTAATGGTAAAGGCGGCGCGAATGCC
+AGCAATACCTTTAGCGGCACGCTGACCGTGACCGTCGATCAGGTTCTGGCCAATGGCAAT
+TTACACGTCGTGGGGGAAAAACAGATCGCGATTAATCAGGGAACGGAATTCATCCGCTTC
+TCCGGCGTGGTAAATCCACGCACCATCAGCGGTAGCAACTCTGTTCCCTCGACACAGGTG
+GCGGATGCGCGGATTGAATATGTCGGGAACGGCTATATTAACGAAGCGCAAAATATGGGC
+TGGCTGCAACGTTTCTTCCTTAATTTGTCGCCGATGATGATCAGTTCATTATGGATCGCC
+AAAACCGGTCTGGACGCGCAGCAAACCAATATGGATGTGATTGCCAATAACCTGGCAAAC
+GTCAGCACCAATGGTTTTAAGCGTCAGCGCGCGGTATTTGAAGATCTGTTGTATCAGACC
+ATCCGCCAGCCGGGCGCGCAGTCGTCCGAGCAGACGACGCTGCCTTCCGGGCTGCAAATC
+GGTACCGGCGTGCGTCCGGTCGCCACGGAGCGCCTGCACAGTCAGGGGAACCTGTCGCAG
+ACCAACAACAGTAAAGATGTGGCGATTAAAGGGCAGGGCTTTTTCCAGGTCATGCTGCCG
+GACGGTACGTCTGCCTATACCCGCGACGGCTCTTTCCAGGTGGATCAGAATGGTCAACTG
+GTGACGGCGGGCGGTTTTCAGGTGCAGCCGGCAATCACCATTCCGGCCAACGCGTTAAGC
+ATCACGATTGGCCGCGACGGCGTGGTCAGCGTTACCCAGCAAGGGCAGGCCGCGCCGGTT
+CAGGTCGGGCAGCTTAACCTGACCACCTTTATGAACGACACCGGTCTGGAAAGCATCGGC
+GAGAACCTCTATATCGAAACGCAATCGTCCGGCGCGCCGAACGAAAGCACGCCGGGGCTC
+AACGGCGCGGGGTTGTTGTATCAAGGGTATGTCGAAACGTCGAACGTTAACGTGGCGGAA
+GAGCTGGTGAACATGATTCAGGTTCAACGCGCCTATGAAATTAACAGTAAAGCAGTATCG
+ACGACCGATCAGATGCTGCAGAAACTGACGCAACTCATGGATCACGCAATTTATACCGCC
+ATGGGGGCGGCCAGCCAGACGCTTAACCAGCAGGCGGTAACGGCCAGCAACCTGGCTAAT
+GCCTCAACGCCGGGCTTTCGCGCGCAGCTTAACGCGCTACGCGCGGTGCCCGTTGATGGC
+CTCTCTTTAGCGACGCGCACGTTGGTTACGGCGTCGACGCCGGGGGCGGATATGACCCAG
+GGTCAGTTGGACTACACTTCCCGCCCGCTGGATGTTGCGTTACAGCAGGACGGCTGGCTG
+GTGGTGCAAGCGGCGGATGGCGCTGAAGGATATACCCGTAACGGGAATATCCAGGTGGGC
+CCGACCGGGCAGTTAACCATTCAGGGACATCCGGTTATCGGCGAAGGCGGCCCGATTACC
+GTTCCGGAAGGGTCGGAAATCACCATTGCGGCAGACGGCACGATCTCCGCGCTCAATCCC
+GGCGACCCGCCAAACACGGTGGCGCCCGTTGGGCGGCTGAAGCTGGTCAAAGCGGAAGGC
+AATGAGGTGCAGCGGAGCGATGACGGTTTATTCCGCCTTACCGCCGAGGCACAGGCTGAA
+CGCGGGGCGGTACTGGCCGCCGACCCGTCAATTCGCATTATGTCGGGCGTGCTGGAGGGC
+AGTAACGTCAAGCCGGTTGAAGCCATGACCGACATGATCGCCAACGCACGTCGTTTTGAA
+ATGCAGATGAAGGTTATCACCAGCGTAGATGAGAACGAAGGGCGAGCTAACCAACTGCTG
+TCGATGAGTATGTCTTTTTCTCAAGCGGTTAGCGGCCTGAACGCTGCGGCCACCAACCTT
+GATGTTATCGGTAATAACATCGCCAACTCCGCCACCTATGGCTTTAAGTCCGGTACGGCA
+TCATTTGCCGATATGTTCGCCGGTTCCAAAGTGGGGTTGGGCGTAAAAGTGGCGGGGATT
+ACCCAGGATTTTACCGACGGTACGACAACGAACACCGGGCGCGGGCTGGATGTCGCGATT
+AGCCAGAACGGTTTTTTCCGCCTGGTAGACAGCAACGGTTCCGTGTTCTATAGCCGCAAC
+GGCCAGTTCAAACTGGACGAGAACCGTAACCTGGTCAATATGCAGGGGATGCAGTTGACC
+GGCTATCCGGCCACCGGTACGCCGCCGACCATTCAGCAGGGGGCGAATCCTGCGCCGATC
+ACCATTCCGAACACGCTGATGGCGGCGAAATCGACCACCACCGCGTCAATGCAGATCAAC
+CTGAACTCAACGGACCCTGTACCGTCTAAAACGCCCTTTAGCGTGAGTGATGCGGATTCG
+TATAACAAAAAAGGCACCGTCACCGTTTATGACAGCCAGGGTAATGCCCATGACATGAAC
+GTCTATTTTGTGAAAACCAAAGATAATGAATGGGCTGTGTACACCCATGACAGCAGCGAT
+CCTGCAGCCACTGCGCCAACAACGGCGTCCACTACGCTGAAATTCAATGAAAACGGGATT
+CTGGAGTCTGGCGGTACGGTGAACATCACCACCGGTACGATTAATGGCGCGACAGCGGCC
+ACCTTCTCCCTCAGCTTCCTTAACTCCATGCAGCAGAACACCGGGGCTAATAACATCGTC
+GCCACCAATCAAAACGGCTATAAGCCTGGCGACCTGGTGAGCTACCAGATTAACAATGAT
+GGCACCGTGGTTGGCAACTACTCCAACGAGCAGGAGCAGGTGCTGGGGCAGATTGTGCTG
+GCTAACTTCGCCAACAACGAAGGTCTGGCATCCCAGGGCGATAACGTCTGGGCGGCGACG
+CAGGCCTCCGGGGTAGCGCTGCTGGGGACTGCCGGTTCCGGCAACTTCGGTAAGCTGACG
+AACGGCGCGCTGGAAGCCTCTAACGTGGATTTGAGTAAAGAGCTGGTGAATATGATCGTC
+GCGCAGCGTAACTACCAGTCGAATGCGCAGACCATCAAAACCCAGGACCAGATCCTCAAT
+ACGCTGGTTAACCTGCGCATGTCTATTGCCGTAAATATGAATGACCCGACCAACACGGGC
+GTCAAAACGACGACCGGCAGCGGGTCGATGACCGGAAGCAACGCTGCCGATCTGCAAAGC
+AGTTTCCTGACCTTACTGGTCGCGCAATTGAAGAACCAGGACCCGACTAACCCATTACAA
+AATAATGAGTTAACGACACAGTTGGCGCAAATCAGTACCGTGAGCGGCATTGAAAAACTG
+AATACGACGCTGGGGGCTATTTCCGGGCAAATCGATAATAGTCAGTCCCTACAGGCGACC
+ACGCTGATTGGACATGGCGTTATGGTGCCTGGCACCACAATTCTGGCGGGTAAAGGCGCG
+GAAGAAGGGGCCGTGACGTCCACGACGCCGTTTGGCGTGGAATTGCAACAGCCTGCGGAC
+AAAGTGACGGCAACCATTACCGATAAAGATGGCCGGGTGGTACGGACGCTGGAGATCGGT
+GAGTTGCGAGCCGGGGTACACACCTTTACCTGGGATGGTAAGCAAACGGACGGAACAACG
+GTACCGAATGGTTCTTACAACATTGCGATTACCGCCAGCAATGGCGGGACGCAACTGGTG
+GCGCAGCCGCTGCAATTCGCTCTGGTACAGGGCGTGACGAAGGGCAGTAACGGCAACCTG
+TTGGATCTGGGTACCTACGGCACCACCACACTCGACGAAGTTCGGCAAATAATCATGCAA
+ATACAGAGCTTCTATCACTCAGCTTCACTAAAAACCCAGGAGGCTTTTAAAAGCCTACAA
+AAAACCTTATACAACGGAATGCAGATTCTCTCAGGCCAGGGCAAAGCGCCGGCTAAAGCG
+CCCGACGCTCGCCCGGAAATTATTGTCCTGCGAGAACCTGGCGCGACATGGGGGAATTAT
+CTACAGCATCAGAAGACGTCTAACCACTCGCTGCATAACCTCTATAACTTACAGCGCGAT
+CTTCTTACCGTCGCGGCAACCGTTCTGGGTAAACAAGACCCGGTTCTAACGTCAATGGCA
+AACCAAATGGAGTTAGCCAAAGTTAAAGCGGACCGGCCAGCAACAAAACAAGAAGAAGCT
+GCGGCAAAAGCATTGAAGAAAAATCTTATCGAACTTATTGCAGCACGCACTCAGCAGCAA
+AATGGCTTACCTGCAAAAGAAGCTCATCGCTTTGCGGCAGTAGCGTTTAGAGATGCTCAG
+GTCAAGCAGCTCAATAACCAGCCCTGGCAAACCATAAAAAATACACTCACGCATAACGGG
+CATCACTATACCAACACGCAGCTCCCTGCCGCAGAGATGAAAATCGGCGCAAAAGATATC
+TTTCCCAGTGCTTATGAGGGAAAGGGCGTATGCAGTTGGGATACCAAGAATATTCATCAC
+GCCAATAATTTGTGGATGTCCACGGTGAGTGTGCATGAGGACGGTAAAGATAAAACGCTT
+TTTTGCGGGATACGTCATGGTGTGCTTTCCCCCTATCATGAAAAAGATCCGCTTCTGCGT
+CAGGCCGGCGCTGAAAACAAAGCCAAAGAAGTATTAGCTGCGGCACTTTTTAGTAAACCT
+GAGTTGCTTAACAGAGCCTTAGAGGGCGAAGCGGTAAGCCTGAAACTGGTATCCGTCGGG
+TTACTCACCGCGTCGAATATTTTCGGCAAAGAGGGAACTATGGTCGAGGATCAAATGCGC
+GCATGGCAATCGTTGACCCAGCCGGGAAAAATGATTCATTTAAAAATCCGCAATAAAGAT
+GGCGATCTACAGACGGTAAAAATAAAACCGGACGTCGCCGCATTTAATGTGGGTGTTAAT
+GAGCTGGCGCTCAAGCTCGGCTTTGGCCTTAAAGCATCAGATAGCTATAATGCCGAAGCG
+CTACATCAGTTATTAGGCAATGATTTACGCCCTGAAGCCAGACCAGGTGGCTGGGTTGGC
+GAATGGCTGGCGCAATACCCGGATAATTATGAGGTCGTCAATACATTAGCGCGCCAGATT
+AAGGATATCTGGAAAAATAACCAACATCATAAAGATGGCGGCGAACCCTATAAACTCGCA
+CAACGCCTTGCCATGTTAGCCCATGAAATTGACGCGGTGCCCGCCTGGAATTGTAAAAGC
+GGCAAAGATCGTACAGGGATGATGGATTCAGAAATCAAGCGAGAGCTCATTTCTTTCCAT
+CAGACCCATATGTTAAGTGCGCCTGGTAGTCTTCCGGATAGCGGTGGACAGAAAATTTTC
+CAAAAAGTATTACTGAATAGCGGTAACCTGGAGATTCAGAAACAAAATACGGGCGGGGCG
+GGAAACAAAGTAATGAAAAATTTATCGCCAGAGGTGCTCAATCTTTCCTATCAAAAACGA
+GTTGGGGATGATAATATTTGGCAGTCAGTAAAAGGTATTTCTTCATTAATCACATCTATG
+AAAAAGTATCTTGCTTTCGCCGTTACGCTGCTGGGTATGGGTAAAGTCATCGCCTGTACT
+ACCCTTTTGGTAGGCAATCAGGCTTCGGCTGACGGCTCCTTTATTATCGCGCGCAACGAG
+GATGGCTCGGCAAATAACGCCAAGCATAAGGTTATTCATCCCGTCGCGTTTCATCAACAA
+GGCGAGTATAAAGCACATCGCAACAATTTTAGCTGGCCGCTTCCGGAGACAGCGATGCGC
+TATACGGCGATTCATGACTTTGATACTAACGATAACGCCATGGGTGAAGCCGGTTTCAAT
+TCGGCGGGCGTCGGAATGAGCGCAACGGAAACCATTTACAACGGCAGAGCGGCGCTGGCT
+GCCGATCCTTACGTGACAAAAACGGGAATCACGGAAGACGCCATTGAGTCCGTGATCCTG
+CCAGTGGCGCAATCGGCGCGTCAGGGCGCCAAATTACTGGGAGATATTATTGAACAAAAA
+GGCGCGGGCGAAGGTTTCGGCGTCGCGTTTATTGATAGCAAAGAGATATGGTATCTGGAG
+ACGGGAAGCGGACATCAATGGCTGGCAGTACGACTTCCGGCAGATAGCTATTTCGTTTCC
+GCCAATCAGGGACGTTTACGCCATTACGATCCGAATGATAACGCGAATTATATGGCGTCA
+CCAACGTTAGTAAGCTTTGCGAAAAAGCAGGGATTATATGATCCGGCCCGCGGCGAATTC
+GACTTTCATCAAGCCTATTCGCAGGATAACAAAAACGATACCACCTATAATTATCCGCGC
+GTCTGGACGCTACAACACCAGTTTAATCCGCATCTGGATACGGTCGTTAGCGAAGGGGAA
+ACATTTTCTGTTTTTTTAACGCCAATAACGAAGATCAGCGTGGCGGCAGTAAAAAACGCG
+TTACGCAATCACTATCAGGGAACGTCGCACGACCCTTATGCCAGTCATAATCCACAAGAA
+CCATGGCGACCTATATCCGTTTTTCGTACCCAGGAGTCACATATTTTACAGGTCAGACCG
+AAATTACCGCAGGCTATCGGCAACGTAGAATACATCGCCTATGGAATGCCATCTCTTAGC
+GTCTATCTCCCCTATTACCAGGGGATGCGTCATTATCAACCCGGAGATGATAAAGGAACC
+GATCGGGCGAGCAACGACTCTACCTACTGGACATTCCGCACGCTGCAAACACTGGTTATG
+CAAGACTACAATACGTTTGCGCCAGATGTGCAACATGCCTGGAAAACATTTGAACAGCAA
+ACAGCTAAGCAACAGTATAAGATGGAGCAGAGCTATCTGAGATTATATGCGTCGCATCCG
+AAAGAAGCACAACGCTTACTGCAAAATTTTGAAGATAAAACGATGCAAAATGCGCAGACG
+CTCGCCCGTCGCCTGACCAATAATATTATTACGACAATGACTTACCGCACAGATATGAAA
+TATCACTTTTCAAGTACGCAGCCAATGGTTAAGTTATCAATGACGCTGCGCCTGACAATT
+TCTTTTATCGCCATACTTATCCTCGCCTGTACCGGCATTAGCTGGACGCTCTATAACGCG
+CTGAGCAAAGAATTAACGTATCGGGATGATATGACGCTAATAAATCGGGCGGCGCAAATG
+CAGCAACTGTTACTGGATGGCGCCAGGCCGGAAAATCTGCCGCTCTATTTCAATCGGATG
+GTGGATACGAAGCAGGATATCTTATTGATCCACTCAGCAACAGGCCATAATGTTGCGATT
+AATCATAGCGGCATCCCCGACCAACGCTTTAACGAGATTCCGCTGGCTAAAAACATCACC
+CGCGAAACCTTATTTCGCCAGGCGGTACAAGGCACGGAGCTGACCGCGGTACGAGTAAAC
+GCCAGAAGCGGCGATAACCCGCTGACCCTTACTATTGCCAGGCTGGCGACGGAAAGGCGG
+CAAATGCTGGCGCAATATCGCCGCAACAGTTTGCTGATTAGCCTTATCGCGATCCTCGTC
+TGTTCGGCGCTCAGTCCATTAGTCATCAGAAACGGGCTGCGGGCCATTACGTCGCTCAGC
+CGACTCACCGCGGCGACAGATAGCGGCACACTTCGCCAGCCGCTGGCGGAACAGGCGTTA
+CCCGTCGAGCTCAGGCCGCTTGGGCAAGCGCTAAATACCATGCGCCAGAAGCTTTCCGAC
+GATTTTGAACGCCTGAACCAATTTGCCGACGATCTGGCGCATGAGCTGCGCACGCCGGTT
+AATATTTTACTGGGGAAGAATCAGGTTATGCTGAGTCAGGAACGCAGCGCCGAAGAGTAT
+CAACAAGCCCTTGTCGATAATATTGAAGAGCTGGAGGGACTGTCGCGACTGACAGAAAAT
+ATTCTCTTTCTGGCACGCGCGGAGCACCAGAATATAGCGGTAAAAAAACAGCCTGTTTCG
+CTCAATGCGCTGGTCGAAAATATGCTGGATTATCTTAGCCCCCTTGCCGAAGAGAAGCAC
+ATCTGTTTTATAAATCAATGTCAGGGAACGGTATGGGCTGACGAAATATTATTACAAAGA
+GTGCTCTCAAACCTGCTGACGAATGCCATCCGTTATTCTGATGAAAACGCCGTGATACGT
+ATTGAAAGCGCTTATGATGATAACGTTGCAGAAATTCGGGTCGCTAATCCGGGCAGCCCC
+ACCGCCGATGCGGATAAGCTTTTCCGGCGTTTTTGGCGAGGAGATAATGCCCGCTACACT
+GCCGGTTTCGGCCTGGGGTTATCGTTAGTTAACGCGATTGCCCTATTGCACGGTGGCTCG
+GCATCTTACCGCTATGCCGATGAACATAATATCTTTTCGGTTCGTCTGCCTGATAGCGGT
+GATAGCATGTCATCTTGTTGGAGATTTACGGATTCGCTAACAAGCCTATGGCATACTGCG
+TTGATGAAGATTTTATTGATTGAAGATAACCAGAAAACCATTGAGTGGGTACGTCAGGGA
+CTCACGGAGGCAGGCTATGTGGTTGATTATGCCTGTGATGGACGAGACGGATTACACCTA
+GCCCTTCAGGAACATTATTCATTGATTATTCTTGATATTATGCTGCCGGGGCTTGATGGA
+TGGCAGGTTTTACGCGCGTTGCGCACTGCATATCAGCCCCCTGTTATTTGCCTGACGGCG
+CGCGACTCGGTTGAGGATCGCGTCAAAGGTCTTGAGGCGGGCGCTAATGATTACCTTGTT
+AAGCCTTTTTCCTTCGCCGAACTGCTGGCCCGGGTGAGAGCTCAACTCAGACAGCATGTC
+CCGGTCTTTACCCGACTGACGATCAATGGTCTGGACATGGATGCCACAAAGCAATCGGTG
+TTACGAAATGGCAAACCGATTTCCCTGACCCGCAAAGAATTCCTGCTCCTCTGGTTACTG
+GCGTCCCGGGCAGGGGAAATCGTGCCCCGAACCGCGATCGCCAGCGAAGTTTGGGGAATT
+AACTTTGATAGTGAAACCAACACCGTTGATGTCGCGATTCGTCGGCTGCGCGCCAAAGTA
+GACGATCCATTTGAAAAGAAGCTCATTATGACCGTCCAGGGGATGGGTTATCGATTACAG
+GCGGAAACGTCGCAGAATGGTATGAAACGATATATACTGGCTACCGCGATAGCGTCTCTT
+GTTGCAGCCCCGGCAATGGCGCTGGCCGCTGGCAGCAATATTCTCAGCGTACATATTCTC
+GATCAGCAAACAGGCAAACCAGCGCCCGGCGTGGAGGTGGTACTGGAGCAGAAAAAGGAT
+AACGGATGGACGCAATTAAACACCGGGCATACCGACCAGGATGGACGAATTAAAGCACTG
+TGGCCCGAAAAAGCTGCCGCGCCGGGGGATTATCGCGTTATTTTTAAAACCGGCCAGTAT
+TTTGAAAGTAAAAAACTGGACACGTTTTTCCCGGAGATTCCCGTCGAGTTTCATATCAGC
+AAAACGAATGAGCACTATCATGTGCCGCTGTTATTAAGTCAGTATGGTTATTCAACCTAT
+CGCGGGAGCATGCAAGTAGATGAACAACGTCTGCGTTTTCGCGATGCGATGGCAAGTCTG
+GCGGCAGCGGTCAACATCGTAACCACGGCGGGTCACGCCGGACGCTGCGGTATCACCGCA
+ACAGCGGTTTGCTCAGTCACTGATACGCCGCCCTCCGTGATGGTATGTATTAATGCCAAT
+AGCGCCATGAACCCCGTTTTTCAGGGCAACGGCAGGCTGTGCATTAATGTACTTAACCAT
+GAGCAGGAGCTGATGGCGCGCCACTTTGCCGGTATGACGGGGATGGCGATGGAGGAGCGT
+TTTCACCAGCCATGTTGGCAAAACGGGCCGCTGGGCCAGCCGGTACTTAACGGCGCGCTG
+GCCAGTCTTGAAGGCGAGATCAGCGAGGTACAAACCATTGGCACGCATCTGGTGTATCTG
+GTGGCGATCAAAAATATTATTCTTAGCCAGGAGGGGCATGGCCTGATTTATTTCAAACGC
+CGTTTTCATCCGGTCAGACTTGAGATGGAAGCGCCTGTTATGGGACGCACACCGGATTAC
+AAAGCCGCCTTTGGCTGCGCTCTGGGCGCTAACCCAGCCTTCTACGGCCAGTTTGAGCAG
+AACGCCCGTAACTGGTACACCCGTATTCAGGAGACCGGCCTGTACTTTAACCATGCAATC
+GTCAACCCGCCCATTGACCGCCACAAACCTGCCGACGAAGTGAAAGACGTCTATATCAAG
+CTGGAGAAAGAGACGGACGCCGGGATTATTGTCAGCGGGGCGAAAGTTGTCGCCACTAAC
+TCCGCCCTGACTCACTACAACATGATTGGTTTCGGCTCAGCCCAGGTGATGGGCGAAAAC
+CCGGATTTTGCTCTGATGTTTGTCGCGCCAATGGATGCCGAAGGCGTAAAACTTATTTCG
+CGCGCCTCGTATGAAATGGTCGCGGGCGCGACGGGCTCGCCGTTTGATTATCCCCTCTCC
+AGCCGTTTTGATGAAAACGATGCCATTCTGGTGATGGACAAGGTGCTGATCCCGTGGGAA
+AACGTATTAATTTACCGTGATTTCGATCGTTGTCGTCGCTGGACGATGGAAGGCGGCTTT
+GCCCGTATGTATCCACTGCAAGCCTGTGTTCGTCTGGCGGTAAAACTTGATTTCATTACC
+GCGCTGCTGAAAAAATCGCTCGAATGTACGGGTACCGTAGAGTTCCGGGGCGTGCAGGCC
+GATCTCGGCGAAGTCGTGGCCTGGCGCAATATGTTCTGGGCATTGAGCGATTCTATGTGT
+TCTGAAGCAACCCCGTGGGTAAACGGCGCCTGGCTACCGGACCACGCCGCGCTGCAAACC
+TATCGTGTGATGGCCCCAATGGCCTACGCGAAAATTAAAAATATTATTGAACGTAACGTT
+ACCAGCGGCCTGATTTACCTGCCTTCCAGCGCCCGCGATCTGAATAATCCGCAAATCGAC
+CAGTACCTGGCGAAATACGTACGCGGCTCTAACGGAATGGACCATGTTGAACGTATCAAA
+ATTCTTAAATTGATGTGGGATGCCATCGGCAGCGAGTTTGGCGGTCGCCATGAGCTGTAC
+GAGATTAACTACTCGGGCAGCCAGGATGAAATTCGTCTGCAGTGTCTGCGTCAGGCCCAG
+AGCTCCGGCAATATGGATAAGATGATGGCAATGGTCGATCGCTGCCTCTCCGAATACGAT
+CAGAATGGCTGGACGGTTTCGCATTTGCACAATAACGACGACATCAATCAACTGGATAAG
+CTGCTGAAAATGCATGATTCATTAACCATCGCCTTGCTTCAGGCGCGCGAAGCGGCAATG
+ACCTATTTCCGCCCCATCGTTAAAAGCCACAATCTGACCGACCAGCAATGGCGCATTGTG
+CGAATCCTGGCCGATAGCCCCTCTATGGATTTTCACGAGCTGGCCTTTCGTACCTGTATT
+TTGCGTCCAAGTCTGACCGGAATATTGACGCGCATGGAGCGAGACGGACTGGTGTTGCGA
+CTCAAGCCGGTTAACGATCAGCGTAAGTTATATGTCATGTTGACGGAGCAGGGACAAACG
+TTGTACGCCCGTGCCCGGAGCGAGGTAGAAGAGGCTTATCGAAAAATTGAGGCCGATTTC
+ACGCCCGAAAAAACACAGCAATTGATGCTGCTGCTGGACGATCTTATTGCTCTGGGGCGC
+CAGCATCCTGATAGCGAAGCGGAAGCAATGAAGGGTACTGTTTTCGCCGTTGCGTTAAAC
+CATCGCAGCCAGCTTGATGCCTGGCAAGAGGCTTTCTCTCAGCCTCCCTATAATGCGCCG
+CCTAAAACCGCAGTGTGGTTCATCAAGCCGCGTAATACGGTGATTCGTCACGGCGAACCC
+ATTCCTTATCCGCAGGGAGAAAAGGTACTGAGCGGCGCGACAGTGGCGCTCATTGTGGGG
+AAAACCGCCAGCCGGATACGCCCTGAAGCGGCGGCGGACTATATCGCCGGGTATGCGCTG
+GCTAACGAGGTCAGCCTGCCGGAAGAGAGCTTTTATCGCCCGGCGATTAAAGCGAAATGT
+CGCGATGGCTTTTGCCCGCTGGGTGAAATGGCGCCGCTGAGTGATGTGGATAATCTCACC
+ATTATCACTGAAATCAACGGACGAGAAGCGGACCACTGGAATACTGCCGATTTACAGCGT
+AGCGCCGCACAACTGCTTAGCGCGTTAAGTGAGTTCGCTACACTTAACCCTGGCGATGCG
+ATCTTACTTGGTACGCCGCAGAATCGCGTTGCGCTGCGTCCCGGCGATCGGGTGCGTATT
+CTGGCGAAAGGTTTACCCGCGCTGGAAAATCCGGTTGTCGCAGAAGATGAATTCGCCCGC
+CACCAGACGTTTACGTGGCCGCTGTCAGCGACGGGAACGTTATTTGCGCTGGGGTTGAAC
+TACGCCGATCACGCCAGCGAGCTGGCATTTACGCCGCCGAAAGAGCCGCTGGTATTTATC
+AAAGCGCCAAACACCTTTACCGAACATCACCAAACGTCGGTGCGCCCGAACAACGTCGAA
+TATATGCACTACGAAGCCGAGCTGGTCGTGGTGATTGGCAAAACGGCGCGTAAGGTGAGC
+GAAGCCGAAGCCATGGAGTATGTGGCCGGTTACACCGTCTGTAACGACTACGCGATCCGC
+GACTATCTGGAAAACTACTACCGTCCGAATCTGCGGGTAAAAAGCCGCGACGGCCTGACG
+CCGATAGGCCCGTGGATTGTGGATAAAGAGGCGGTTTCTGATCCGCACAACCTGACGTTA
+CGCACCTTTGTCAACGGTGAGCTGCGGCAGGAAGGGACGACCGCCGATCTGATCTTCAGC
+ATCCCGTTCCTGATTTCTTATCTGAGCGAATTTATGACGTTGCAACCGGGCGACATGATT
+GCCACCGGTACGCCGAAAGGGCTGTCCGATGTGGTGCCGGGGGATGAAGTTGTCGTTGAA
+GTAGAAGGCGTGGGTCGCCTGGTTAACCGAATCGTCAGTGAGGAGAGCGCAAAAATGAAG
+AAAATAAATCATTGGATTAACGGCAAAAACGTTGCAGGTAACGACTACTTCCAGACCACT
+AACCCGGCGACCGGTGATGTGCTGGCGGAAGTAGCCTCCGGCGGTGAAGCAGAAGTGAAC
+CAGGCTGTCGCGGCGGCAAAAGAGGCGTTCCCGAAATGGGCCAACCTGCCGATGAAAGAG
+CGCGCGCGCCTGATGCGCCGCCTTGGCGACCTGATTGACCAGCATGTGCCGGAAATCGCG
+GCGATGGAAACCGCCGACACCGGCCTGCCTATTCACCAGACTAAAACGTGCGTGCTGATC
+CCGCGCGCCTCGCATAACTTCGAATTCTTCGCCGAAGTGTGCCAGCAGATGAACGGCAAG
+ACCTATCCGGTTGACGATAAAATGCTCAATTATACGCTGGTGCAGCCCGTCGGCGTCTGC
+GCGCTGGTGTCGCCGTGGAACGTGCCGTTTATGACCGCGACTTGGAAAGTTGCGCCGTGC
+CTGGCGCTGGGTAACACCGCGGTGCTCAAAATGTCCGAGCTGTCGCCGCTGACTGCCGAC
+AGGCTGGGCGAGCTGGCACTGGAGGCAGGAATTCCGGCAGGCGTGCTGAACGTGGTGCAG
+GGCTACGGCGCGACGGCGGGCGATGCGCTGGTACGCCACCATGACGTGCGTGCGGTGTCG
+TTTACCGGCGGTACCGCCACCGGTCGCAATATCATGAAAAATGCCGGGCTGAAAAAATAC
+TCGATGGAGCTGGGCGGCAAATCGCCGGTGCTGATTTTTGAAGACGCCGACATTGAGCGC
+GCGCTGGACGCCGCGCTGTTCACCATCTTCTCGATCAACGGCGAACGCTGCACCGCTGGG
+TCGCGCATCTTTATCCAGCAGAGCATTTACCCTGAGTTCGTGAAGCGCTTTGCCGAACGC
+GCGAATCGCCTGCGTGTCGGCGATCCGACCGACCCGAACACCCAGGTCGGCGCGCTGATT
+AGCCAACAGCACTGGGAGAAAGTCTCCGGTTATATCCGCCTCGGCATTGAAGAGGGGGCA
+ACGCTGCTGGCGGGCGGTGCGGAAAAACCCACTGACCTGCCTGCGCATCTGAAAGGCGGT
+AACTTCCTGCGCCCAACCGTGCTGGCCGATGTCGACAACCGTATGCGCGTTGCGCAGGAA
+GAGATCTTTGGGCCGGTCGCCTGCCTGCTGCCATTCAAAGACGAAGCGGAAGGGTTACGT
+TTGGCGAACGATGTGGAATACGGTCTGGCCTCTTATATCTGGACCCAGGACGTGAGCAAA
+GTGTTGCGCCTGGCGCGTGGGATTGAAGCCGGCATGGTCTTCGTCAACACCCAGAACGTC
+CGCGACCTGCGCCAGCCGTTCGGCGGCGTGAAAGCCTCCGGTACCGGGCGCGAAGGCGGC
+GAATATAGCTTCGAAGTGTTTGCGGAAATGAAAAACGTCTGCATCTCAATGGGCGACCAT
+CCTATCCCAAAATGGGGAGTTATGGGCAAGTTAGCGTTAGCAGCAAAAATTACCCACGTG
+CCGTCGATGTATCTTTCTGAACTGCCAGGAAAAAATCACGGTTGTCGTCAGGCAGCCATT
+GATGGGCATATTGAAATTGGCAAGCGTTGCCGCGAAATGGGCGTTGACACCATTATCGTA
+TTCGACACCCACTGGCTGGTGAATAGCGCTTACCACATTAATTGTGCCGACCATTTCCAG
+GGCGTCTATACCAGCAACGAATTGCCGCACTTTATTCGCGACATGACCTATGACTATGAC
+GGTAATCCGGCGCTCGGCCATCTGATCGCCGACGAGGCGGTCAAACTGGGCGTGCGCGCC
+AAAGCGCACAACATCCCGAGCCTGAAGCTGGAGTATGGCACGCTGGTGCCGATGCGCTAC
+ATGAACAGCGACAAGCACTTCAAAGTGGTCTCCATCTCGGCGTTCTGCACTGTGCATGAT
+TTTGCCGACAGCCGCAAACTGGGCGAAGCCATTCTCAAGGCGATTGAGAAATATGACGGT
+ACCGTAGCGGTATTCGCCAGTGGTTCTCTGTCGCACCGTTTTATTGACGACCAACGGGCG
+GAAGAGGGGATGAACAGCTACACCCGCGAGTTCGATCATCAAATGGACGAGCGCGTGGTC
+AAGCTGTGGCGCGAAGGCAAATTCAAGGAGTTTTGCACCATGTTGCCGGAGTACGCCGAC
+TACTGCTACGGCGAAGGCAACATGCACGACACGGTCATGCTACTGGGAATGCTGGGGTGG
+GACAAATACGACGGCAAGGTGGAGTTCATCACCGACCTGTTCGCCAGCTCCGGTACCGGC
+CAGGTAAACGCTGTTTTCCCGCTGCCTGCGATGCCGCACTTTATTGCTGAATGTACTGAA
+AATATTCGCGAGCAGGCTGATTTACCAAGCCTGTTCAGCAAGGTAAACGAGGCGCTGGCC
+GCCACCGGGATTTTCCCCATCGGCGGTATCCGCAGTCGCGCCCACTGGCTGGATACCTGG
+CAGATGGCTGACGGTAAGCATGATTACGCGTTTGTGCATATGACGCTGAAAATCGGCGCC
+GGGCGCAGCCTGGAGAGCCGTCAGGAAGTCGGCGAAATGCTGTTTGGGCTGATTAAAGCC
+CACTTCGCCGACCTGATGGAGAACCGCTATCTGGCGCTGTCGTTTGAGATTGCCGAGTTA
+CATCCAACGCTCAATTACAAACAAAACAACGTACACGCGTTATTTAAAATGCTCGATAAA
+CAGACCCATACCCTGATCGCTCAGCGACTTAATCAGGCTGAAAAACAGCGTGAACAGATT
+CGCGCAGTGTCGCTGGATTATCCCAACATCACTATTGAAGATGCCTATGCCGTACAGCGT
+GAATGGGTCAATATCAAGATTGCCGAAGGGCGCACGCTCAAAGGCCACAAAATCGGCCTG
+ACCTCAAAAGCGATGCAGGCCAGCTCGCAAATCAGCGAACCGGATTACGGCGCGCTGCTT
+GACGATATGTTCTTCCATGACGGCGGAGATATCCCCACCGACCGTTTTATCGTCCCGCGT
+ATTGAAGTGGAGCTGGCGTTCGTGCTGGCGAAACCGCTGCGCGGCCCTCACTGCACGCTG
+TTCGACGTCTACAACGCCACGGATTATGTGATTCCGGCGCTGGAACTGATTGACGCCCGC
+AGCCACAACATCGACCCGGAAACCCAGCGCCCGCGCAAAGTGTTCGACACCATTTCCGAC
+AACGCCGCCAACGCCGGGGTGATCCTCGGTGGTCGCCCCATCAAACCAGACGAGCTGGAT
+CTGCGCTGGATCTCCGCGCTGCTCTATCGCAACGGCGTGATCGAAGAAACCGGCGTCGCC
+GCAGGCGTGCTGAATCATCCGGCCAACGGCGTGGCGTGGCTGGCGAACAAGCTTGCCCCC
+TACGATGTCCAGCTTGAAGCCGGGCAGATCATCCTCGGCGGCTCGTTCACCCGCCCGGTG
+CCGGCGCGCAAGGGCGACACCTTCCATGTCGATTACGGCAACATGGGCGCGATCAGTTGC
+CGGTTTGTGATGAAAAATGCTTTCAAAGACGCGTTAAAAGCGGGGCGCCCGCAAATCGGT
+TTGTGGCTGGGGCTTGCCAACAGTTACAGCGCTGAACTGTTAGCGGGCGCCGGCTTCGAC
+TGGCTACTGATTGACGGTGAACACGCGCCAAACAACGTGCAGACGGTGTTGACCCAGTTG
+CAGGCGATTGCGCCTTATCCCAGCCAGCCGGTGGTGCGTCCGTCATGGAACGATCCGGTA
+CAGATTAAGCAACTGCTCGACGTCGGCGCGCAAACGCTGCTGATACCGATGGTGCAGAAT
+GCCGATGAAGCGCGAAACGCCGTGGCGGCTACGCGTTATCCGCCTGCCGGTATTCGCGGC
+GTGGGCAGCGCGCTGGCGCGGGCATCGCGCTGGAATCGCATTCCGGACTATCTCCACCAG
+GCCAACGACGCCATGTGCGTACTGGTGCAGATTGAAACGCGTGAGGCGATGAGCAATCTG
+GCGTCAATTCTCGACGTGGATGGCATTGACGGCGTGTTTATTGGCCCGGCGGATCTCAGC
+GCCGATATGGGCTTTGCCGGCAATCCGCAGCACCCGGAAGTGCAGGCGGCGATTGAGAAC
+GCCATCGTGCAGATACGCGCGGCGGGGAAAGCGCCGGGGATTCTGATGGCCAATGAAGCA
+CTGGCGAAACGTTATCTGGAACTGGGGGCGCTATTTGTCGCCGTCGGCGTTGACACCACG
+CTGCTGGCGCGCGGAGCGGAGGCGCTGGCGGCGCGCTTTGGCGCAGAAAAAAAACTGTCC
+GGTGCGTCCGGCGTCTATATGAGCGACACATCATCTGCACTTCCGGAAAGCCCCGAGTCT
+GTCGGTTCGCACAACGCGCTCAGCACGGGTCAACAAACCGTCATAAATAAACTGTTCCGC
+CGACTGATCGTATTTTTATTCGTGTTGTTTATCTTCTCGTTTTTAGACCGTATCAACATC
+GGTTTTGCCGGGTTGACGATGGGGCAGGATCTGGGGTTAAGCGCCACCATGTTTGGTCTT
+GCCACGACGCTGTTTTACGCCACCTACGTCATTTTCGGCATTCCCAGCAACGTGATGTTG
+AGCATCGTCGGCGCCCGCCGCTGGATTGCGACCATTATGGTGCTATGGGGCATTGCATCT
+ACCGCCACGATGTTCGCGGTGGGACCGAAAAGCCTGTATGTGCTGCGAATGCTGGTGGGC
+ATTACCGAAGCGGGCTTTTTGCCAGGAATATTGCTCTATTTAACCTACTGGTTCCCGGCA
+TTTTTCCGCGCCCGCGCCAACGCATTATTTATGATTGCCATGCCGGCCACTACCGCGTTG
+GGGTCAATTGTCTCCGGCTATATTTTATCGCTGGACGGCATATTCAATCTGCATGGATGG
+CAGTGGTTATTCCTGTTGGAAGGATTTCCGTCAGTTTTGTTAGGCATTATGGTCTGGTTT
+TACCTGGATGATACCCCGGCAAAAGCCAAATGGCTGACGGCAGAGGATAAAAAATGTTTG
+CAGGAGATGATGGATAATGATCGCCTGACGCTGGTTCAGCCTGAGGGGGCCATCAGCCAT
+AACGCCATGCAGCAGCGTAGCCTGTGGCGCGAAGTATTCACGCCAATTGTACTGATGTAT
+ACGCTGGCCTATTTTTGCCTTACCAATACGCTTAGCGCCATTAGTATCTGGACGCCGCAA
+ATCCTGAAAAGTTTTAATGAAGGCAGCAGCAATATCACCATCGGCCTGCTGGCGGCGATC
+CCGCAGATTTGTACTGTTCTGGGCATGATTTACTGGAGCCGCCATTCGGACAAACATCAG
+GAGCGTAAACACCACACTGCGTTACCGTTCCTGTTTGCCGCCGCGGGCTGGCTGCTGGCG
+TCGGCGACCGACCGTAACCTGATCCAGCTCCTGGGGATCGTGATGGCATCCACGGGTTCC
+TTTAGCGCGATGGCGATCTTCTGGACCACGCCGGATCAGTCGATCAGTTTACGCGCCAGG
+GCGATAGGCATTGCGGTCATCAATGCCACCGGCAATATTGGCTCCGCGCTCAGCCCGGTT
+ATGATTGGCTGGCTAAAAGATATCACTGGTAGCTTCAATAGCGGACTCTGGTTTGTCGCT
+TCTCTGTTAGTCGTCGGCGCCGCCATTATCTGGCTCATTCCCATGAAAGCATCGCGTCCG
+CGCGCCACCCCTATGTGCCAACGTGCGATCGCCAATATTGATATCAGCAAAGAGTATGAC
+GAAAGCATGGGCAGTAACGATGTGCATTATCAGTCGTTTGCTCGTATGGCGGATTTCTTT
+GGTCGTGATATGCAGGCGCATCGCCACGACCAGTTTTTTCAAATGCACTTTCTTGATACC
+GGGCAGATTGAGCTACAGCTCGACGATCATCGCTATTCGGTGCAGGCGCCGCTATTTGTG
+CTAACGCCGCCCTCGGTGCCGCATGCTTTTATTACCGAATCGGATAGCGATGGTCATGTT
+CTGACGGTACGCGAAGAGCTGGTTTGGCCGCTGCTGGAAGTGCTTTATCCCGGCACCAGA
+GAGGCCTTCGGCCTGCCGGGAATCTGCCTGTCGCTGGCGGATAAACTCAACGAGCTGGCG
+GCGCTCAAACATTACTGGCAGCTAATTGAGCGGGAGTCCACGGAACAACTGGCTGGCTGC
+GAACATACCTTGGTACTACTGGCGCAGGCGGTATTTACCTTGCTGTTGCGTAATGCGAAG
+CTGGACGATCATGCCGCAACCGGGATGCGCGGTGAACTGAAACTTTTTCAGCGCTTTACC
+CTGTTAATTGACAACCACTTCCATCAGCACTGGACGGTGCCCGATTATGCCTGTGAGTTG
+CATATTACCGAATCTCGTTTGACCGATATTTGCCGACGTTTTGCTAATCGCCCGCCTAAA
+CGCCTGATTTTTGATCGGCAATTACGCGAGGCGAAACGACTGCTGCTTTTTTCCGACAAT
+GCTGTCAACGAGATCGCCTGGCAATTAGGTTTTAAAGATCCGGCTTATTTCGCCCGTTTC
+TTTAATCGCCTTGCTGGCTGTTCTCCTTCGCAGTTTCGCCAACGTGAAGTTCCTTCTTTT
+CTCAACATGATGAAAAAAAGCGTCGCTATGCTGGCGGTTTGTATGCTGGCGCAAAGCCAC
+CTTGCCATTGCTGCCGGTGCTCCTGCGCCTCAAGAGATCAACATTGTTTTACTGGGCACC
+AAAGGCGGGCCTTCTTTGCTCAATACAGCCAGACTACCGCAAGCGACGGCGCTCACTATC
+GGCGATAAGATATGGCTGATAGATGCCGGCTACGGCGCCAGTCTGCAACTGGTGAAAAAT
+GGCATTCCACTGCGCAACATCAATACTATTTTGCTCACCCATCTGCACAGCGACCACATA
+CTGGATTATCCTTCCTTGCTGATGAATGCCTGGGCAAGTGGCCTGAAAGACCATACCATA
+CAGGTTTATGGCCCGCCGGGAACCCAGGCGATGACGAAGGCTAGCTGGAAGGTCTTTGAC
+AGGGATATCACGTTACGCATGGAAGAAGAGGGGAAACCCGATCCGCGCAACCTGGTTAAG
+GCGACCGATATCGGCCAGGGCGTCATCTATAAAGATGAACTGGTCACAATAAGCGCGCTG
+AAAGTGCCTCATTCCCCTTTCCCGGACGGTGAAGCGTTTGCTTACCGTTTTGATACTCAG
+GGTAAGCGAATCGTCTTCTCTGGCGATACGTCCTGGTTTCCTCCGCTTGCAACGTTTGCC
+CAGGGGGCGGATATCCTGGTACATGAGGCGGTACATGTCCCTTCGGTAGCAAAACTGGCT
+AATAGTATTGGCAACGGAAAAACGCTGGCTGAAGCGATTGCGTCGCATCACACCACGATT
+GAAGATGTCGGTAAGATTGCTCGCGAGGCCCACGTGAAAAAACTGGTGTTAAGTCATCTG
+GTGCCTGCGACGGTTGCGGATGACGTCTGGCAACAGGAAGCCATGAAAAATTACCCGGGC
+CCTGTCATTGTCGGTCATGACAATATGACGATAAGCGTACCGATGGCTAACATCACTGTC
+ACCTTTACCATCACCGAATTTTGTTTGCACACCGGCGTGACGGAAGAGGAGCTAAACGAA
+ATCGTCGGACTTGGCGTAATTGAGCCTTACGAAGACGATAACGCCGACTGGCAATTCGAC
+GATCGCGCAGCGAGCGTGGTACAACGCGCGCTACGCTTACGCGAGGAGCTGGCGCTCGAC
+TGGCCAGGGATCGCGGTCGCGTTAACGCTGCTGGAAGAGAATTCACGGCTGCGCGAAGAA
+AACCGGTTACTGCTGCAACGCCTTTCTCGCTTTATCTCGCATCCCATGGAACTTAAGGAT
+TATTACGCCATTATGGGCGTGAAACCGACGGACGATCTCAAGACGATTAAGACCGCCTAT
+CGCCGACTGGCCCGCAAGTACCATCCAGATGTCAGCAAAGAACCCGATGCCGAAGCCCGT
+TTCAAAGAGGTTGCTGAAGCATGGGAAGTGCTGAGTGATGAGCAACGGCGCGCCGAGTAT
+GACCAGTTATGGCAACACCGTAACGATCCACAATTTAATCGCCAGTTCCAGCAACACGAA
+GGCCAGCCGTATAACGCCGAAGATTTTGATGATATTTTCTCGTCTATTTTTGGTCAGCAC
+GGTCGTCATTCGCACCACCGCCACGCCGCACGCGGTCATGATATCGAAATTGAAGTGGCG
+GTATTCCTGGAAGAAACGCTGGAAGAGCACCAGCGTACGATTAGCTATTCCGTCCCCGTT
+TATAACGCGTTCGGCCTGGTGGAGCGGGAAATTCCCAAAACATTGAATGTGAAAATCCCG
+GCTGGCGTCAGCAACGGGCAACGAATCAGACTGAAAGGCCAGGGCACGCCGGGGGAAAAC
+GGCGGACCTAATGGCGATTTATGGCTCGTTATCCATATTGCCCCGCATCCGCTCTTTGAT
+ATCGTCAATCAGGATCTGGAAGTCGTCCTTCCGCTTGCCCCATGGGAGGCGGCGCTCGGC
+GCTAAGGTGTCTGTGCCAACGCTTAAAGAGCGTATTTTGCTGACCATTCCCCCCGGCAGC
+CAGGCAGGTCAGCGGCTGCGTATCAAAGGAAAAGGATTAGCCAGTAAAAAGCACACTGGC
+GATCTCTATGCCATCATCAAAATCGTTATGCCGCCGAAACCTGACGAGAAAACAGCTGCC
+CTGTGGCAACAACTGGCGGACGCGCAGTCGTCCTTTGACCCACGCCAGCAATGGGGGAAA
+GCAATGGCGAAACAACAACGGATGGGCTGGTGGTTTCTTTGCCTTGCATGTGTCGTGGTA
+ATGGTTTGTACCGCGCAACGCATGGCGGGCCTGCACGCCTTGCAGATGCAGGCGACGGCC
+TCTGCTGCGGTGGTCAGCGCTCCCTCCTCGACAGATGACGGCTCGCCGGTCACTCCCTGC
+GAATTAAGCGCCAAGTCGCTGCTGGCGGCGCCTCCAGTACTCTTTGAAGGTGCTATCCTT
+GCGCTTTATCTACTGCTTTCCTTACTGGCGCCTGTCCGGGTCATGCGCCTGCCGTTTTCG
+CCTCCACGGGCTATTTCGCCGCCCACATTACGGGTACATCTACGATTTTGTGTCTTCCGT
+GAAATGATGATTTTATTCAGGCGGATACTGTTCTGCCTGTTATGGCTTTGGCTGCCCGTC
+TCCTGGGCGGCGGAAAGCGGCTGGCTGCGTTCGCCCGATAACGACCATGCCAGCATACGG
+CTACGTGCCGATACGTCCGCTAACAGTGAGACCCGGCTGTTGCTGGATGTCAAACTGGAA
+AACGGCTGGAAAACCTACTGGCGCGCGCCGGGGGAAGGGGGCGTGGCACCCTCTATCGCC
+TGGAAAGGCGACATGCCTGAGGTAAGCTGGTTCTGGCCAACCCCCTCGCGCTTTGATGTG
+GCGAATATCACCACCCAGGGATATCACGACGAGGTGACCTTTCCGATGATCGTGCGCGGT
+ACGCCGCCGGCGACCTTGCGCGGTGTGTTGACGTTATCAACCTGCAGCAATGTTTGTCTG
+TTGACCGATTACCCCTTTTCCGTGACGCCCACTGTGCAGAATGCCGATTTTGCCCATGAC
+TATGCGCGGGCGATGGGTAAAGTTCCGCTCCGCAGTGGGCTAACGGACTCGCTTGACGTT
+GGCTATCGCCCGGGAGAACTGGTGGTCACTGCTACGCGAGCGGCGGGCTGGTCATCGCCC
+GGGCTCTATCTTGACACCATAGATGACGTCGATTTTGCGAAGCCTCGCCTGCGCGTAGAG
+GGCGACAGGTTACAGGCGACGGTGCCGGTGACGGACAGTTGGGGCGAAAAGGCGCCCGAT
+TTGCGCGACAAATCGCTGACCCTCGTGTTAGCCGATGGCGCTATCGCCCAGGAGAGCACG
+CAAACCATTGGCGCTGCGCCAGCGCAAACGCCGGACAATGCGGCGCTACCTTTCTGGCAA
+GTTGTAATGATGGCGCTAATCGGCGGACTGATTCTTAATTTAATGCCCTGCGTACTGCCT
+GTTCTGGGCATGAAACTTGGCTCTATTTTATTGGTAGAGGAAAAAAGCCGCTCTCACATC
+AGGCGACAATTTTTGGCTTCGGTCGCCGGTATCATTGCGTCATTTATGGCGCTGGCGGCG
+TTTATGACCCTCCTTCGCCTGTCAAACCATGCGCTGGCCTGGGGAGTCCAGTTCCAGAAT
+GCATGGTTTATTGGTTTTATGGCGCTGGTGATGTTGTTGTTTAGCGCCAGCCTGTTCGGG
+CTTTTTGAGTTCAGGCTTCCCTCATCTATGACCACGAAACTGGCCACTTACGGCGGTAAC
+GGTATGTCGGGACATTTCTGGCAGGGGGCGTTCGCCACGCTGCTGGCGACGCCTTGTAGC
+GCGCCGTTTCTGGGCACGGCGGTCGCGGTGGCGCTCACGGCGTCGCTGCCGACGCTGTGG
+GGGCTGTTCCTTGCGCTTGGCCTGGGAATGAGCGCGCCGTGGCTACTGGTCGCGATACGA
+CCAGGGCTTGCGCTACGTTTACCGCGCCCCGGGCGTTGGATGAATGTCCTGCGCAGGATC
+CTCGGTCTGATGATGCTGGGGTCGGCTATCTGGCTGGCGACGTTACTCCTGCCGCATTTC
+GGCTTCACTGCGTCAAAGAGCGCGCAAGACACGGTTCAGTGGCAACCGTTGAGTGAACAG
+GCAATCCAGTCGGCGCTGGCGCAGCATAAGCGGGTATTTGTCGATGTCACTGCGGACTGG
+TGTATTACCTGTAAAGTGAATAAATACAACGTCCTGCAAAAAGAGGATGTGCAGGCCGCC
+TTGCAACAGCCGGATGTTGTGGCGCTGCGGGGAGACTGGACGCTGCCGTCCGATGCCATT
+ACAGATTTTCTGAAAACGCGCGGCCAGGTCGCCGTGCCGTTTAATCAGGTATATGGCCCC
+GGTTTGCCGGAAGGGGAGGCACTGCCCACTTTGCTGACCCGCGATGCGGTATTACAAACG
+TTGAAAAAAGCGAAAGGAATAACCCAAATGAAATACATGATTGTTTTACTGCTGGCGCTG
+TTTTCGACGCTGAGCATCGCGCAAGAAACCGCTCCTTTTACGCCGGATCAGGAAAAGCAG
+ATTAAAAATCTGATCCATGCGGCGTTGTTTAACGATCCTGCCAGCCCGCGGATAGGCGCT
+AAACACCCTAAGCTGACGCTGGTGAACTTTACGGATTACAACTGCCCGTACTGCAAACAG
+CTCGATCCGATGCTGGAAAAGATTGTGCAGAAATATCCTGACGTTGCGGTCATTATTAAA
+CCGCTGCCATTCAAAGGAGAGAGTTCCATACTGGCGGCGCGTATTGCGCTGACCACCTGG
+CGCGATCATCCGCAACAGTTCCTCGCGCTACATGAAAAACTTATGCAAAAGCGCGGTTAC
+CATACGGATGACAGTATTAAACAGGCCCAGCAGAAAGCAGGGGCGACGCCAGTGACGCTG
+GATGAAAAAAGCATGGAAACGATACGCACTAATTTGCAGTTGGCAAGACTGGTCGACGTG
+CAAGGAACGCCAGCGACGATCATTGGCGACGAGCTGATTCCGGGCGCAGTGCCCTGGGAT
+ACGCTGGAAGCGGTGGTGAAAGAAAAACTGGCGGCTGCCAATGGCGGGATGGCGGGTAAA
+CTGCGGCGTTGGCTGCGTGAAGCCGCGGTTTTTCTGGCGCTCCTCATCGCGATAATGGTG
+GTCATGGACGTCTGGCGCGCGCCGCAGGCGCCTCCGGCGTTTGCCGCGACACCATTACAT
+ACGCTGACGGGAGAGTCGACAACTCTGGCGACCTTGAGCGAGGAACGCCCCGTACTGCTC
+TATTTTTGGGCCAGCTGGTGCGGGGTATGCCGCTTTACCACGCCTGCGGTCGCTCACCTG
+GCGGCGGAAGGGGAAAACGTCATGACCGTTGCGCTCCGCTCCGGCGGTGATGCTGAGGTT
+GCCCGCTGGCTGGCGCGCAAGGGCGTTGACTTCCCGGTCGTCAATGATGCTAACGGCGCC
+TTATCCGCTGGCTGGGAAATCAGCGTGACGCCAACGCTGGTGGTGGTTTCACAAGGTCGG
+GTTGTGTTCACCACCAGCGGCTGGACCAGCTATTGGGGCATGAAGCTTCGGCTGTGGTGG
+GCAAAAACGTTCATGAAAAAATCATTACTCGCTGTTGCTGTGGCAGGGGCTGTTTTGTTG
+TCATCCGCCGTACAGGCGCAGACAACGCCGGAAGGTTATCAATTACAACAGGTGCTGATG
+ATGAGCCGCCATAATCTGCGGGCGCCGCTGGCGAATAATGGCAACGTACTGGCGCAGTCG
+ACGCCGAACGCCTGGCCGGCGTGGGACGTTCCCGGCGGGCAACTGACGACGAAAGGCGGC
+GTGCTGGAAGTCTATATGGGACACTACACACGTGAATGGCTGGTCGCGCAGGGGCTGATA
+CCGTCGGGAGAATGTCCGGCGCCCGACACGGTATATGCCTATGCGAATAGTTTGCAGCGC
+ACCGTCGCCACCGCGCAATTTTTCATTACCAGCGCTTTCCCCGGCTGTGATATTCCTGTT
+CATCATCAGGAAAAAATGGGCACTATGGACCCTACCTTCAATCCGGTGATTACCGATGAT
+TCCGCCGCGTTCCGGCAACAGGCCGTACAGGCGATGGAAAAGGCGCGTAGTCAGCTACAT
+CTTGATGAGAGTTATAAACTGCTTGAGCAGATAACGCATTATCAGGACTCGCCGTCCTGC
+AAAGAGAAGCATCAGTGTTCGCTAATCGACGCGAAAGATACCTTCAGCGCGAACTATCAG
+CAAGAGCCTGGCGTGCAGGGGCCGCTGAAAGTAGGGAACTCGCTGGTGGATGCGTTTACC
+CTGCAATATTACGAAGGCTTTCCGATGGATCAGGTCGCTTGGGGCGGGATCCACACCGAT
+CGGCAGTGGAAGGTGCTGTCAAAACTGAAAAACGGCTACCAGGACAGCCTGTTTACCTCA
+CCCACGGTGGCGCGCAATGTCGCTGCGCCGCTGGTAAAATATATCGATAAGGTGCTGGTT
+GCCGAGCGCGTTAGCGCGCCGAAGGTTACCGTGCTGGTGGGGCATGATTCCAATATCGCG
+TCGCTGCTGACGGCGCTGGATTTTAAACCCTATCAGCTCCATGACCAGTATGAGAGAACG
+CCGATTGGTGGTCAGCTTGTCTTCCAACGCTGGCATGACGGTAACGCTAACCGGGATTTG
+ATGAAAATCGAGTATGTCTACCAGAGCGCCCGGCAGTTACGTAATGCGGAAGCGTTAACG
+CTCAAATCGCCTGCGCAAAGGGTAACGCTGGAACTGAAAGGATGTCCGGTGGATGCGAAC
+GGCTTCTGTCCGCTGGATAAGTTCGATAACGTCATGAACACTGCTGCAAAAATGCCAACT
+CAAGAAGCAAAAGCGCACCGCGTCGGCGAATGGGCAAGCCTGCGTAATACGTCGCCGGAA
+ATTGCCGAAGCCATTTTTGAAGTCGCTCACTATGACGAGAAACTGGCAGAAAAAATATGG
+GAAGAAGGTAGCGATGAGGTGCTGATCAAAGCCTTTGAGAAAACGGACAAAGACTCGCTC
+TTCTGGGGCGAACAAGTCATCGAACGTAAGAACGTAATGGCAAAGATTCTGGTGCTCTAT
+TATTCCATGTACGGACACATTGAAACCATGGCGCACGCGGTGGCGGAAGGGGCAAAGAAA
+GTCGACGGCGCAGAGGTCATTATAAAGCGTGTGCCAGAAACAATGCCGCCTGAAATCTTC
+GCAAAAGCTGGCGGTAAAACGCAAAACGCACCGGTTGCCACCCCACAGGAGCTGGCGGAT
+TACGATGCCATTATTTTTGGTACGCCAACCCGGTTTGGCAATATGTCAGGCCAGATGCGT
+ACCTTCCTGGACCAAACCGGCGGACTGTGGGCATCCGGCGCGCTATACGGCAAGCTCGGC
+GGCGTGTTCAGTTCTACCGGAACGGGCGGCGGCCAGGAGCAGACCATCACCTCGACCTGG
+ACTACGCTTGCCCATCATGGGATGGTGATTGTCCCGATAGGCTATTCCGCACAGGAACTG
+TTTGACGTCTCCCAGGTTCGCGGCGGTACGCCTTACGGCGCAACGACTATCGCTGGAGGC
+GACGGTTCACGTCAACCAAGCCAGGAGGAACTCTCTATCGCTCGCTATCAGGGGGAATAC
+GTCGCCGGTCTGGCAGTCAAACTCAACGGCATGGCAAACCATCGTGGCGGTTCCGGTAAT
+TTTGCGGAAGACCGCGAAAGAGCATCAGAAGCAGGTCGTAAAAGTGGTCAGCACAGCGGG
+GGCAATTTTAAGAATGACCCGCAGCGTGCATCCGAAGCAGGCAAAAAAGGGGGCAAAAGC
+AGTAACCGTAATCGCATGTCGCAACGCACAGAGAAAAAAATCGGGAAACGTTCGCAGGCC
+ACCGGTGCAAAACGGCAGCTTATCTTAACCGCCGCGCTTGCCGTTTTTTCCCAGTATGGC
+ATTCATGGCGCGCGTCTTGAACAGGTCGCCGAGCGGGCAGGCGTCTCCAAAACCAATCTG
+CTTTATTATTATCCCTCGAAAGAGGCGCTGTATGTCGCGGTAATGCGACAGATTCTGGAT
+GTCTGGTTGGCGCCGCTCAAGGCGTTTCGCGCAGAATTTTCCCCTCTGGAGGCCATCAAA
+GAGTATATCCGTCTCAAGCTGGAGGTTTCGCGTGATTATCCGCAGGCGTCGCGGCTCTTC
+TGCATGGAGATGCTGGCGGGCGCGCCGCTCTTAATGGATGAACTGACCGGCGATCTAAAA
+GCGTTGATAGATGAAAAATCCGCGCTGATTGCCGGATGGGTGCACAGCGGGAAACTCGCG
+CCCGTTTCTCCGCATCATTTGATCTTCATGATTTGGGCCGCCACGCAACATTACGCCGAT
+TTCGCCCCTCAGGTTGAAGCGGTAACCGGCGCGACGCTTCGCGATGAAGCCTTTTTCAAC
+CAAACGGTCGAAAGCGTTCAGCGCATTATTATTGAAGGGATTCGCGTGCGTATGAAACGA
+ATTTTCCTTACCTGCGCGGCGTTGTTGTTCAGCAGTCAGGCGTTGGCCGATGAGTGTGCC
+AGCGCCAGTACGCAGCTGGAAATGAATCGCTGCGCCGCCGCGCAATACCAGGCGGCAGAT
+AAAAAGCTGAACGAAACCTATCAAAGCGCGATTAAGCGTGCGCAACCGCCGCAGCGTGAG
+CTATTGCAAAAAGCGCAGGTGGCATGGATTGCCCTGCGCGACGCCGATTGCGCGCTGATT
+CGCTCAGGTACGGAGGGCGGCAGCGTTCAACCCATGATCGCCAGCCAGTGCCTGACCGAT
+AAAACGAACGAACGCGAAGCGTTTTTAGCCTCGCTGCTGCAATGTGAAGAGGGTGATTTG
+AGCTGCCCACTGCCGCCAGCCGGTATGGGAACCACCACGATGGGGGTTAAGCTGGACGAC
+GCCACGCGCGAACGGATCAAAATGGCCGCGTCGCGTATCGATCGCACGCCGCACTGGTTA
+ATAAAACAGGCAATCTTTAGCTATCTGGACAAGCTGGAAAATAGCGATACGCTACCGGAG
+CTACCTGCGCTGTTTGCCGGCGCGGCAAATGAAAGCGAGGAGCCGGTCGCGCCGCAGGAT
+GAGCCGCATCAGCCCTTTCTGGAGTTTGCCGAACAGATTCTTCCCCAATCCGTCTCTCGC
+GCCGCCATCACCGCCGCCTGGCGCCGCCCGGAAACCGATGCGGTGTCAATGCTAATGGAA
+CAGGCGCGCCTGTCGCCGCCTGTCGCTGAGCAGGCGCATAAACTGGCGTATCAACTGGCG
+GAGAAATTGCGCAATCAAAAATCCGCCAGCGGTCGCGCGGGTATGGTGCAAGGCCTGTTG
+CAGGAGTTTTCCCTCTCTTCGCAAGAAGGCGTAGCGCTGATGTGTCTGGCGGAAGCGCTG
+CTGCGTATTCCCGACAAAGCTACGCGCGATGCGTTAATTCGCGACAAAATCAGTAATGGC
+AACTGGCAGTCGCATATTGGCCGTAGCCCGTCGCTGTTTGTAAACGCCGCCACCTGGGGG
+CTGCTCTTTACCGGCCGACTGGTCTCAACGCATAACGAAGCCAATCTTTCGCGCTCGCTG
+AACCGCATTATCGGCAAGAGCGGCGAACCGTTAATCCGCAAAGGCGTCGACATGGCGATG
+CGTTTAATGGGCGAGCAGTTCGTGACTGGCGAAACCATTGCTCAGGCGCTGGCGAATGCC
+CGAAAACTGGAAGAGAAAGGGTTCCGCTATTCTTACGATATGCTGGGCGAAGCCGCGTTA
+ACCGCCGCCGATGCGCAGGCCTATATGGTCTCTTACCAGCAAGCGATTCATGCCATCGGC
+AAAGCGTCTAACGGTCGCGGTATTTACGAAGGGCCAGGCATCTCGATTAAGCTGTCCGCC
+CTGCATCCACGCTATAGTCGCGCGCAATACGATCGGGTAATGGAGGAGCTTTATCCGCGC
+CTGAAATCCCTGACGCTGCTGGCGCGCCAGTATGATATCGGTCTCAATATCGACGCCGAA
+GAGGCGGATCGTCTGGAGATCTCGCTTGATCTGCTGGAAAAACTCTGCTTCGAACCCGAA
+CTGGCGGGCTGGAACGGCATTGGCTTTGTGATTCAGGCTTACCAGAAACGCTGCCCGCTG
+GTCATTGATTATTTAGTCGATCTGGCCTCCCGTAGCCGCCGTCGGCTGATGATTCGTCTG
+GTGAAAGGCGCCTACTGGGATAGCGAGATCAAACGCGCGCAAATGGAAGGGCTGGAGGGC
+TATCCAGTTTATACCCGCAAAGTGTATACCGATGTCTCTTATCTGGCCTGCGCGAAAAAA
+CTGCTCGCCGTCCCTAATCTGATCTACCCGCAGTTCGCGACCCATAACGCTCACACACTG
+GCGGCGATTTATCATCTGGCCGGGCAAAATTACTATCCGGGTCAGTACGAATTCCAGTGC
+CTGCACGGCATGGGAGAACCGCTGTATGAACAGGTCACCGGTAAAGTGGGGGACGGAAAA
+CTTAACCGTCCCTGCCGTATTTACGCGCCGGTGGGAACACACGAAACCCTGCTGGCCTAT
+CTGGTACGACGCCTGCTGGAAAACGGCGCCAACACCTCTTTTGTCAACCGCATCGCCGAT
+GCCACCCTACCGCTCGATGAACTGGTGGCCGACCCGGTCGAGGCCGTGGAAAAACTGGCG
+CAGCAGGAAGGTCAGGCTGGCATACCGCATCCAAAAATTCCGCTGCCGCGCGATCTGTAC
+GGCGAAGGTCGGATAAACTCCGCCGGACTTGATTTAGCGAATGAACATCGCCTCGCCTCG
+CTTTCTTCTGCCCTGTTAAGCAACGCCATGCAGAAATGGCAGGCCAAACCTGTGCTGGAA
+CAACCGGTGGCCGACGGTGAGATGACGCCGGTTATCAACCCGGCGGAACCGAAAGATATT
+GTTGGCTGGGGACGCGAAGCGACAGAAAGCGAGGTTGAACAGGCGTTGCAAAACGCGGTC
+AATCAGGCGCCGGTTTGGTTTGCGACGCCGCCGCAAGAACGCGCCGCTATTTTGCAGCGG
+GCGGCGGTATTGATGGAAGACCAAATGCAGCAGTTGATTGGCCTGTTGGTGCGTGAAGCG
+GGGAAAACGTTCAGCAACGCCATTGCCGAAGTGCGCGAAGCGGTAGACTTCCTCCATTAT
+TATGCCGGTCAAGTGCGTGACGATTTCGATAACGAAACGCATCGCCCGTTAGGGCCGGTG
+GTCTGTATCAGTCCGTGGAACTTTCCGCTGGCCATTTTCACTGGCCAAATCGCCGCCGCG
+CTGGCGGCAGGTAACAGCGTTCTGGCGAAACCGGCAGAGCAGACATCGCTGATTGCCGCC
+CAGGGCATTGCCATTTTGCTGGAAGCGGGCGTACCGCCGGGCGTCGTGCAACTGTTGCCG
+GGACGGGGAGAAACCGTCGGCGCCCAGCTTACCGCCGATGCGCGTGTACGCGGCGTGATG
+TTTACCGGTTCCACGGAGGTCGCGACGTTGTTGCAGCGCAACATCGCCACGCGTCTTGAC
+GCCCAGGGGCGCCCTATTCCGTTGATTGCGGAAACCGGCGGTATGAACGCTATGATTGTC
+GACTCTTCCGCGCTCACCGAGCAGGTGGTCGTGGATGTGCTGGCTTCCGCCTTCGACAGC
+GCCGGACAACGCTGTTCCGCGCTCCGCGTGCTGTGTTTGCAGGACGATATCGCCGAACAT
+ACGCTGAAAATGTTACGCGGCGCGATGGCGGAGTGTCGGATGGGGAATCCAGGCCGTCTG
+ACGACCGATATCGGGCCGGTGATCGATAGCGAGGCCAAAGCCAACATTGAACGTCATATC
+CAGACGATGCGCGCCAAAGGCCGCCCGGTTTTCCAGGCCGCGCGTGAAAACAGCGATGAC
+GCGCAGGAATGGCAGACCGGTACGTTTGTTATGCCCACGCTTATTGAGCTGGAAAACTTC
+GCAGAACTGGAAAAAGAGGTCTTCGGGCCCGTGCTGCACGTCGTGCGTTATAACCGTAAC
+CAACTGGCGGAGCTTATCGAACAGATTAACGCTTCCGGCTACGGGCTAACGCTGGGCGTA
+CATACCCGTATTGATGAAACCATTGCGCAAGTCACCGGTTCCGCCCATGTCGGCAACCTG
+TACGTTAACCGTAATATGGTGGGCGCGGTCGTCGGCGTCCAGCCGTTTGGCGGCGAAGGC
+CTGTCCGGCACCGGGCCAAAAGCGGGAGGGCCGCTCTATCTCTACCGCCTGCTGGCACAC
+CGCCCGCCCAATGCGCTCAATACGACGCTGACTCGTCAGGATGCGCGTTACCCGGTGGAT
+GCGCAGCTTAAAACCACGCTACTCGCGCCGTTGACCGCTCTGACGCAATGGGCGGCGGAT
+CGCCCGGCGCTACAGACGCTCTGCCGACAATTCGCCGATCTGGCGCAGGCCGGCACGCAG
+CGCCTGCTACCGGGGCCGACCGGCGAGCGTAATACCTGGACGCTGTTGCCGCGTGAACGG
+GTGTTATGCCTGGCTGATGATGAACAGGACGCGTTGACGCAGCTTGCCGCCGTTCTCGCC
+GTCGGCAGTCAGGCGCTATGGTCAGACGACGCCTTCCACCGCGATCTGGCGAAACGTCTC
+CCCGCCGCCGTCGCGGCGCGTGTCCAGTTTGCGAAAGCGGAAACGCTGATGGCGCAGCCG
+TTTGACGCGGTGATTTTCCACGGCGACTCCGACAAGCTGCGAACCGTGTGCGAAGCCGTC
+GCCGCCCGCGAAGGCGCGATAGTGTCGGTACAGGGGTTCGCCCGCGGCGAAAGCAATATG
+CTGCTGGAACGGCTCTATATTGAACGTTCGCTGAGCGTAAACACTGCCGCCGCTGGCGGT
+AATGCCAGCCTGATGACAATTGGCATGGCTATTAGCACACCGATGTTGGTGACATTCTGT
+GTCTATATTTTTGGCATGATATTGATTGGGTTTATCGCCTGGCGCTCAACCAAAAACTTT
+GATGACTATATTCTTGGCGGTCGCAGCCTGGGGCCGTTTGTTACGGCTTTATCAGCCGGC
+GCGTCGGATATGAGCGGCTGGCTGTTAATGGGGCTGCCTGGCGCTATCTTTCTGTCGGGG
+ATCTCTGAAAGCTGGATCGCCATTGGCCTGACGTTAGGCGCATGGATTAACTGGAAGCTG
+GTGGCCGGGCGCCTGCGCGTGCATACCGAATTTAACAATAACGCGCTCACGCTGCCGGAC
+TATTTTACCGGTCGGTTTGAGGATAAGAGCCGAGTCCTGCGTATTATTTCCGCGCTGGTC
+ATTCTGCTGTTTTTCACTATCTATTGCGCATCAGGTATTGTCGCTGGGGCACGACTGTTC
+GAAAGCACCTTCGGTATGAGCTATGAAACCGCACTGTGGGCGGGGGCCGCGGCAACCATT
+ATTTATACCTTTATCGGCGGGTTTCTTGCCGTTAGCTGGACGGATACCGTTCAGGCCAGC
+CTGATGATTTTTGCGTTAATCCTGACGCCGGTGATGGTTATTGTCGGCGTAGGCGGTTTT
+AGCGAGTCGCTGGAAGTGATCAAGCAAAAGAGCATCGAGAATGTCGACATGCTCAAGGGG
+CTGAATTTTGTCGCTATTATTTCTCTGATGGGCTGGGGGCTGGGTTACTTCGGTCAGCCG
+CATATCCTGGCGCGCTTTATGGCGGCGGATTCCCATCACAGTATTGTTCATGCGCGTCGT
+ATCAGTATGACCTGGATGATTCTGTGTCTGGCGGGCGCGGTGGCGGTGGGCTTCTTTGGC
+ATTGCGTACTTTAACAATAACCCCGCGCTGGCCGGGGCGGTGAACCAAAACTCAGAACGC
+GTATTTATTGAACTGGCGCAGATCCTGTTTAACCCGTGGATTGCCGGTGTTCTGCTGTCT
+GCTATCCTGGCGGCGGTGATGTCGACGTTGAGCTGTCAGTTGCTGGTATGCTCCAGCGCG
+ATTACGGAAGATTTATATAAGGCTTTTCTGCGTAAAAGCGCCAGCCAGCAAGAGCTGGTA
+TGGGTAGGGCGAGTGATGGTGCTGGTGGTAGCGCTGATCGCCATTGCGCTGGCGGCGAAT
+CCTGATAACCGTGTGCTGGGGCTGGTGAGCTACGCCTGGGCTGGATTCGGCGCGGCATTT
+GGACCTGTTGTCCTGTTTTCTGTGATGTGGTCGCGTATGACACGTAACGGCGCGCTGGCG
+GGAATGATTATTGGCGCGGTGACGGTTATCGTCTGGAAACAATATGGCTGGCTGGATCTG
+TATGAGATTATCCCTGGCTTCATTTTCGGCAGCCTGGGGATCGTAATCTTTAGCCTGCTT
+GGCAAAGCGCCGACAGCAACGATGCAGGAACGCTTTGCAAAAGCGGACGCGCATTATCAT
+TCCGCGCCGCCGTCGAAGCTACAGGCGGAAATGGTAATGTCCGCACCAGGACACATTGTT
+TACAGTAGTTACAACACCCTGTACGGACATTCTCTCTCCGGTGGTGGTCTTGTCATCTTA
+AAAGCTCTCATCATTTCCCTTACTGTCCATACCCATGACGCCATATGTGGTGCGCGTAGC
+CGTGTGTGGCGTCGTTTCAAAAAGCAAGCTAAGGCTTACAAGGAAGCCAACCCTCAGATG
+TGTGTGCGCATAATCGCGTTCAAGAGAACGCGGGTGATGTATACCTACAACTCAAGGTGC
+TATCCATGGGAAGACAAAAAGCAGATGGGAAGACAAAAAGCAGTGATCAAAGCTCGTCGT
+GAAGCAAAGCGTGTGTTGAGACGAGATTCGCGTAGTCATAAGCAACGTGAAGAAGAATCG
+GTCACGTCACTGGTACAGATGGGCGGAGTAGAAGCCATTGGCATGGCGCGCGATAGTCGC
+GATACCTCTCCTGTTAAGGCGCGAAATGAAGCACAGGCGCATTATCTGAACGCTATCGAC
+AGTAAACAGCTTATTTTTGCGACCGGCGAAGCCGGCTGCGGAAAAACATGGATCAGTGCG
+GCAAAGGCGGCAGAAGCATTGATTCATAAGGACGTCGAGAGGATCATTGTGACGCGTCCG
+GTATTGCAGGCTGATGAAGATCTTGGTTTTTTGCCCGGTGATATCGCTGAAAAATTCGCG
+CCTTATTTTCGTCCCGTCTACGATGTCCTGCTTAAACGGTTGGGCGCGTCCTTTATGCAA
+TATTGTTTGCGCCCGGAAATCGGTAAGGTAGAAATTGCCCCGTTCGCCTATATGCGTGGG
+CGTACTTTTGAAAATGCGGTCGTGATCCTCGACGAGGCGCAAAATGTGACTGCGGCGCAA
+ATGAAAATGTTTTTGACGCGATTAGGCGAAAATGTCACGGTCATTGTCAATGGCGATATT
+ACGCAATGCGACCTGCCGCGCGGTGTGCGTTCCGGGTTGAGTGATGCGTTGGAACGCTTT
+GAAGAAGATGAAATGGTGGGGATTGTGCATTTCAACAAAGACGACTGCGTGCGCTCGGCG
+CTTTGTCAGCGAACGCTCCACGCATACAGCATGGAGCCTCAACCCCCACGTCTGAAACCC
+GGAAAAATCCTTGACACTCTGGGTGCTATGCAAAAAAGCCTGACACGTGCCTCGCAGCGT
+ATTGCGCAATATATTTTAGCCTTCCCCAGACAGGTGACACAGTCATCTATTGCGGATTTG
+TCGCGCGACACACAGGCCGGAGAAGCCACGGTTATTCGCTTTTGTCGCACCCTGGGCTAT
+AAAGGTTTTCAGGATTTTAAAATGGACCTGGCCATTGAACTTGCCACTACCGAGTCTGAT
+GACAGTAGTCCTCTACTGGATGCCGAAGTTAGCGAATCCGACGATGCCCACGCGATTGGT
+TTAAAATTGCAGAACACCATTAGTAATGTATTATCTGAAACGCTAAATCTGCTGGATATG
+CAACAGGTTCTCGGTGTCGTGGACGCCCTACGTCACTGTCACTCAGTTTATATGTTTGGT
+GTGGGCTCATCGGGGATCACGGCGCTGGATATGAAACACAAGCTAATGCGTATGGGTTTA
+CGGGGCGATGCGGTAAGCAATAACCATTTTATGTACATGCAGGCTACGCTATTGAAAGCA
+GGCGATGTCGCGATGGGTGTCAGTCACTCGGGCACATCGCCAGAAACAGTGCATTCACTC
+CGATTGGCCCGACAGGCTGGCGCCACCACAGTCGCCATTACCCATAATCTGGGTTCTCCA
+TTATGTGAAGAGGCCGATTTTTGCCTGATCAATGGTAATCGGCAAGGAATGTTGCAGGGT
+GACTCGATCGGTACGAAAGCCGCGCAGCTTTTCGTCTTTGACCTGCTCTATACCCTTCTT
+GTACAGTCCTCGCCGGAACAGGCCCGAGAAAGCAAATTACGGACAATGAATGCCCTGGAC
+ATGACAAAAGTGATATGTCTGAAAGTCCAGGGCGGCATTGGTGAAATTTTTACGGTGACG
+CAGCAGGCGGATAAATTCTTGCCGGCTACGCAGTTCCACTGGAGCTGGACGGAAAGCACA
+GTACCTGTATTGATGATTGGGTTTCTGTTTGCCAATATTCAGCAATTTACTGCCAGTCAG
+GATGTGGTCCAACGCTATATGGTGACTGACTCCATAGAGGAAACGAAGAAAACATTACTT
+ACAAATGCCAAACTGGTTGCGGTGATCCCTGTTTTCTTTTTTGCTATCGGCTCGGCATTA
+TTTGTCTACTATCAGCAACAGCCACAATTATTACCGGCGGGATTCAACACTGGCGGCATT
+TTGCCCTTATTCGTGGTCACGGAAATGCCAGTCGGCATTGCAGGGTTGATAATCTCCGCT
+ATTTTCGCTGCCGCGCAGTCGAGCATCTCCAGCAGCTTAAACAGCATTTCCAGTTGTTTT
+AATTCCGATATCTATCAGCGGTTGAGTCATAAAAAAGGAACGCCAGAAAACCGTATGAAA
+ATAGCTAAGTTAGTTATTCTGGTCGCGGGCCTGATAAGTAGCGCGGCCTCGGTATGGCTG
+GTCATGGCCGATGAATCAGAGATCTGGGATGCATTTAATAGTCTGATAGGTCTGATGGGA
+GGGCCAATGACCGGTCTGTTGATGCTGGGCATTTTCTTTAAACGAGCAAATGCCGGGAGT
+GCGGTTTTAGGAATTATTATGAGCGTCATTACCGTGCTGGGCACACGCTATGCCACTGAC
+CTTAACTTCTTCTTTTATGGGGTCATTGGCTCGCTAAGCGTGGTGATCAGCGGCGTTATT
+TTCGCCCCGTTATTTGCCCCGGCACCGCCATTGACGCTGGATGAAAAACCTGAACCAAAG
+GTGACATTAATGTCACTATTAGCCAGGCTGGAACAAAGTGTACACGAAAACGGTGGGCTG
+ATTGTCTCATGCCAACCGGTACCAGGCAGCCCTATGGATAAACCTGAAATTGTGGCTGCA
+ATGGCACAGGCAGCGGCTTCGGCGGGTGCGGTCGCTGTGCGCATTGAAGGCATTGAGAAT
+CTGCGGACTGTTCGTCCCCATCTTTCTGTTCCTATTATTGGGATAATTAAACGTGACCTT
+ACAGGGTCGCCAGTCCGTATCACTCCATATTTACAGGATGTTGACGCCCTGGCGCAGGCA
+GGTGCCGATATTATCGCTTTTGATGCCTCATTCCGCTCTCGCCCGGTTGATATTGATAGT
+TTACTGACACGTATTCGCCTGCATGGATTACTGGCGATGGCAGACTGTTCAACCGTGAAT
+GAAGGCATAAGTTGCCATCAGAAAGGAATCGAATTCATTGGTACAACACTGTCTGGCTAT
+ACCGGTCCCATCACGCCGGTTGAGCCAGATTTGGCAATGGTGACACAACTGAGTCATGCA
+GGTTGTCGTGTTATTGCCGAGGGGCGCTATAACACGCCTGCACTGGCGGCCAATGCTATT
+GAGCATGGTGCCTGGGCAGTTACCGTTGGTTCCGCTATCACCCGTATCGAGCATATCTGT
+CAGTGGTTCAGTCACGCAGTAAAACGCATGAAAAATTTTAAGAAAATGATGACGCTAATG
+GCGCTATGTTTATCAGTTGCTATCACCACATCAGGATATGCAACCACGCTTCCTGATATA
+CCAGAACCACTGAAAAATGGTACTGGCGCTATTGATAATAATGGCGTGATTTATGTCGGC
+TTAGGTACCGCAGGGACATCCTGGTATAAAATTGATCTTAAAAAGCAACATAAAGACTGG
+GAGCGTATAAAGTCGTTTCCTGGTGGAGCTCGTGAGCAATCCGTGTCGGTATTTTTAAAT
+GATAAGCTGTATGTTTTTGGTGGCGTAGGGAAAAAAAACAGTGAATCACCGTTGCAGGTT
+TATAGCGATGTGTACAAATACTCACCGGTGAAAAATACATGGCAAAAAGTTGATACTATA
+TCTCCAGTTGGATTAACAGGGCATACGGGAGTAAAATTAAACGAAACGATGGTACTTATT
+ACCGGAGGGGTTAATGAGCATATCTTTGATAAGTATTTTATTGATATAGCGGCTGCGGAT
+GAAAGTGAAAAAAATAAAGTCATCTATAATTATTTTAATAAACCTGCCAAAGATTATTTT
+TTTAATAAAATCGTATTTATCTACAATGCTAAAGAGAACACATGGAAGAATGCCGGTGAG
+CTGCCAGGCGCGGGGACGGCAGGATCGTCATCGGTAATGGAAAATAATTTCTTGATGCTG
+ATTAATGGTGAGCTCAAACCGGGTTTACGTACCGATGTGATTTACCGCGCCATGTGGGAT
+AACGATAAGCTAACATGGTTGAAGAACAGCCAGTTACCGCCATCGCCTGGAGAACAACAG
+CAGGAAGGGTTGGCCGGAGCATTTTCGGGCTATAGCCACGGTGTCCTGCTTGTCGGTGGT
+GGCGCGAATTTTCCGGGAGCAAAACAAAATTATACTAATGGAAAGTTTTATTCCCACGAA
+GGGATAAATAAAAAATGGCGAGATGAAGTCTATGGTTTGATTAATGGCCATTGGCAATAT
+ATGGGTAAAATGAAACAACCTCTCGGCTATGGTGTATCAGTAAGTTATGGTGATGAAGTT
+TTCCTTATTGGTGGTGAAAATGCTAAAGGGAAACCTGTTTCGTCTGTAACCTCCTTTACC
+ATGCGTGATGGTAATTTATTAATAAAAATGAAAATCAACAGATATCTTCTGGGTATGGTT
+TCGTTTATAGCATTTTCATCATATCTACAAGCGGCAACCCTTGATTATCGGCATGAATAT
+GCTGATAGAACCAGAATTAATAAAGACCGTATTGCTATAATTGAAAAGCTTCCTAACGGC
+ATTGGTTTTTATGTCGATGCCAGCGTTAAATCGGGAGGAGTAGATGGTGAGCAGGATAAG
+CATTTAAGCGATCTCGTCGCAAACGCTATAGAACTGGGCGTAAGTTATAATTATAAAGTT
+ACGGACCATTTTGTTTTGCAGCCTGGATTTATATTTGAAAGCGGTCCAGACACTTCAATT
+TATAAGCCTTATTTAAGGGCGCAATATAATTTTGATTCTGGTGTTTATATGGCTGGTCGT
+TACCGTTATGACTATGCAAGGAAGACAGCTAACTATAATGATGATGAGAAAACGAATAGA
+TTTGATACTTATATAGGTTATGTTTTTGATGAGTTGAAATTGGAATATAAATTTACCTGG
+ATGGATAGCGATCAAATTAAATTTGATAACAAAAAAACAAACTATGAACATAATGTGGCT
+TTAGCCTGGAAACTGAATAAGTCATTTACACCATACGTTGAGGTCGGAAATGTAGCGGTG
+AGAAATAATACCGATGAGAGACAGACCCGTTATCGCGTTGGATTACAATACCACTTTGTG
+ATAGCAAAATTCTTCCCGTGGTATAGCGAGATAACACGTCCACAAAAAAATGCTTTATTT
+TCAGCATGGCTGGGTTACGTTTTTGATGGCTTCGACTTTATGCTGATTTTCTACATTATG
+TATCTGATCAAGGCTGACTTAGGATTGACAGATATGGAGGGCGCATTCCTTGCCACAGCG
+GCCTTTATTGGGCGACCATTTGGCGGGGCGCTATTTGGTCTGCTGGCAGACAAATTTGGC
+CGTAAGCCGTTAATGATGTGGTCGATAGTTGCCTATTCTGTAGGTACAGGGTTAAGTGGC
+CTGGCTTCCGGTGTAATTATGCTGACGCTTAGTCGTTTTATTGTCGGTATGGGGATGGCG
+GGGAAGTATGCTTGCGCTTCTACTTATGCCGTGGAAAGTTGGCCAAAGCATTTAAAATCT
+AAAGCGAGCGCATTTCTGGTTTCAGGTTTCGGTATTGGTAACATCATAGCAGCCTATTTT
+ATGCCGTCATTTGCCGAAGCGTATGGTTGGCGTGCTGCTTTTTTTGTCGGTTTGCTACCC
+GTTCTTTTAGTAATCTACATCCGGGCCAGGGCTCCTGAATCTAAAGAGTGGGAAGAAGCC
+AAACTCAGTGGTCTCGGAAAGCATTCACAAAGTGCCTGGTCAGTTTTCTCTTTGTCAATG
+AAAGGGCTATTTAATCGAGCTCAATTTCCACTGACATTATGTGTATTTATTGTTCTGTTC
+TCTATTTTCGGCGCAAACTGGCCGATCTTTGGTCTACTGCCTACATATTTGGCGGGAGAG
+GGCTTTGATACGGGCGTGGTCTCTAATTTAATGACGGCGGCGGCATTCGGCACTGTATTG
+GGAAATATCGTTTGGGGTCTGTGCGCAGATAGAATTGGTTTGAAGAAAACGTTCAGCATT
+GGTCTTCTCATGTCCTTTTTATTCATTTTCCCGTTATTCAGAATTCCGCAAGATAATTAT
+TTACTGCTGGGCGCATGTTTATTCGGTTTAATGGCGACTAACGTAGGTGTTGGCGGGCTG
+GTTCCCAAATTTCTCTACGACTACTTTCCTCTTGAGGTTCGTGGTTTGGGTACCGGGCTT
+ATTTATAATCTTGCTGCGACATCAGGCACATTCAATTCAATGGCGGCGACCTGGCTTGGA
+ATAACAATGGGGCTAGGCGCTGCGCTAACGTTCATTGTTGCTTTCTGGACCGCAACAATT
+CTACTCATTATTGGCCTATCCATTCCGGATAGACTAAAAGCACGTCGTGAAAGGTTTCAG
+TCAACAAAAGAATTTATGACGAAATACGGTGTTATAGGTACAGGTTATTTTGGCGCTGAA
+CTGGCGCGATTTATGTCTAAGGTTGAAGGGGCGAAAATCACTGCGATTTACGATCCGGTA
+AATGCGGCTCCGATAGCGAAAGAGCTGAACTGTGTCGCCACTTCAACGATGGAGGCGCTT
+TGTACCCATCCTGATGTGGATTGCGTAATTATTGCTTCACCAAATTACTTACATAAAGCG
+CCGGTCATTGCGGCGGCTAAAGCGGGTAAACACGTGTTTTGTGAAAAACCTATCGCCTTA
+AATTACCAGGATTGTAAGGATATGGTTGATGCCTGCAAAGAAGCTGGTGTTACCTTTATG
+GCGGGTCACGTTATGAACTTTTTTCACGGGGTTCGCCACGCTAAAGCGCTCATCAAAGCC
+GGTGAAATCGGTGAAGTTACACAAGTTCACACTAAACGTAATGGTTTTGAAGACGTGCAG
+GATGAGATCTCATGGAAGAAGATTCGCGCAAAGTCAGGTGGGCATCTGTACCATCACATT
+CACGAGCTAGATTGTACACTGTTCATCATGGATGAAACCCCATCCCTGGTTTCAATGGCG
+GCGGGGAATGTTGCGCACAAAGGTGAAAAATTTGGTGATGAAGATGATGTTGTCCTAATC
+ACCCTTGAGTTTGAAAGCGGTCGTTTCGCGACACTTCAGTGGGGATCATCGTTCCACTAC
+CCTGAGCACTATGTATTAATTGAGGGCACGACAGGTGCAATTCTCATTGATATGCAAAAC
+ACGGCTGGTTATCTAATAAAAGCGGGCAAAAAAACACACTTTCTTGTGCATGAAAGCCAG
+GCGGAGGATGATGATCGTCGCAACGGTAACATATCCAGCGAGATGGATGGCGCAATCGCT
+TATGGTAAACCCGGTAAACGTACGCCGATGTGGCTCTCATCAATTATGAAACTGGAGATG
+CAGTACTTGCATGATGTGATAAACGGTCTGGAGCCAGGCGAGGAGTTTGCTAAATTGCTA
+ACGGGAGAAGCGGCGACAAATGCCATTGCTACCGCTGATGCTGCGACGCTTTCTTCAAAC
+GAGGGGCGCAAAGTTAAACTCACTGAAATTCTTGGCATGGAGATAATTTTTTATCACCCG
+ACATTTAACGCCGCCTGGTGGGTAAATGCGCTGGAGAAGGCTCTCCCACATGCGCGCGTT
+CGTGAATGGAAGGTCGGTGATAACAACCCCGCAGACTATGCGCTTGTATGGCAGCCCCCG
+GTTGAAATGCTGGCCGGAAGACGCTTAAAAGCCGTCTTTGTGCTGGGCGCGGGGGTGGAT
+GCAATTCTGAGTAAATTAAATGCGCATCCGGAAATGCTGGACGCCTCCATTCCTCTATTC
+CGTCTGGAAGATACCGGAATGGGCCTGCAAATGCAGGAGTATGCCGCCAGCCAGGTATTA
+CACTGGTTCCGTCGTTTCGATGATTATCAGGCGCTGAAAAATCAGGCGCTATGGAAACCG
+TTGCCGGAATATACCCGCGAAGAGTTTAGCGTCGGTATCATAGGCGCAGGGGTACTGGGC
+GCAAAAGTGGCAGAAAGTCTACAGGCGTGGGGGTTCCCGTTACGTTGCTGGAGTCGTAGC
+CGCAAATCCTGGCCTGGCGTGGAAAGTTATGTAGGGCGTGAAGAACTGCGCGCTTTCCTG
+AACCAGACGCGGGTGCTGATTAATCTGCTGCCGAATACGGCCCAAACGGTAGGAATTATT
+AATAGCGAATTGTTGGATCAATTGCCGGATGGCGCTTACGTGCTGAATCTCGCGCGCGGC
+GTTCATGTTCAGGAGGCGGATCTGCTGGCTGCGCTTGATAGCGGTAAGCTAAAAGGCGCG
+ATGTTGGATGTCTTTAGCCAGGAACCGTTACCGCAGGAAAGTCCATTATGGCGCCATCCG
+CGAGTCGCCATGACGCCGCACATTGCGGCAGTCACCCGTCCGGCGGAAGCCATCGATTAT
+ATTAGCCGCACCATTACCCAGCTGGAGAAGGGAGAGCCGGTGACGGGGCAGGTGGATCGG
+GCGAGAGGATATTGGATGATGCGCGCGATGAACATACTTCTTTCTATTGCTATCACTACG
+GGCATCCTTTCTGGAATATGGGGATGGGTGGCCGTCTCCCTGGGGTTACTAAGCTGGGCC
+GGTTTTTTAGGCTGTACGGCTTATTTGGCCTGTCCGCAGGGCGGCTTTAAGGGATTGTTG
+ATTTCCGCCTGTACGCTGTTAAGCGGGATGGTGTGGGCGCTGGTCATTATTCACGGTAGC
+GCGTTGGCGCCGCATCTGGAAATTGTGAGTTACGTGTTGACGGGGATCGTGGCATTCCTG
+ATGTGTATCCAGGCAAAGCAGCTATTGCTTTCTTTTGTTCCGGGAACATTTATCGGCGCC
+TGCGCGACATTTGCAGGGCAGGGTGAGTGGCGGTTGGTATTACCGTCGCTGGCGCTGGGG
+CTAATCTTTGGCTATGCCATGAAAAAGAGTGGGCTATGGCTGGCATCACGCCGCGAGCAA
+CATTCAGCGAATACGGCGGTCACAAAGATGAAACGCTATCTGACCTGGATTGTAGCAGCA
+GAGTTACTGTTCGCTACCGGAAACCTCCATGCCAATGAAGTTGAAGTCGAGGTTCCCGGA
+TTGTTAACCGACCATACCGTCTCTTCCATAGGACATGAATTCTATCGTGCATTCAGCGAC
+AAATGGGAAAGCGAATACACCGGCAACCTGACCATTAATGAAAGACCCAGTGCGCGTTGG
+GGAAGCTGGATCACCATAACGGTAAACCAGGACGTTATTTTCCAGACCTTTTTATTTCCA
+ATGAAAAGAGACTTCGAGAAAACCGTCGTCTTCGCATTAGCGCAAACAGAGGAAGCATTA
+AATCGCCGACAAATAGATCAAACGCTCTTAAGTACGAGTGATTTAGCGCGTGATGAATTC
+ATGTCCGTAATCAAGAAAAATATCCCTGCCATAGGCCTGTGTATCTGCGCTTTTTTTATC
+CATTCTGCGGTAGGGCAACAAACGGTACAGGGCGGCGTTATCCATTTTCGCGGCGCGATT
+GTTGAGCCACTGTGCGATATTTCTACTCACGCCGAAAATATTGATTTAACCTGCCTACGC
+GAAGGTAAAAAGCAAATGCACCGGATAGACCTTCGGCAGGCATCTGGATTACCGCAGGAT
+ATTCAGTCCATTGCGACGGTACGGCTGCATTATCTCGATGCGCAAAAAAGCCTGGCGGTG
+ATGAATATTGAGTACCGTATGACATCACGTCTTCAGGTCATACAGGGTGATATCACTCAA
+CTTAGCGTCGATGCGATTGTGAATGCCGCTAACGCATCATTAATGGGCGGCGGTGGCGTA
+GACGGCGCAATTCATCGCGCGGCGGGGCCGGCATTGCTGGACGCCTGTAAACTCATCCGT
+CAGCAACAGGGCGAATGTCAGACGGGACATGCGGTTATCACGCCTGCTGGCAAGCTTTCG
+GCAAAGGCGGTTATTCACACAGTGGGGCCCGTCTGGCGAGGCGGCGAACACCAGGAAGCT
+GAGCTACTCGAAGAGGCATACCGGAATTGTTTGCTGCTTGCCGAGGCGAATCACTTTCGT
+TCCATCGCTTTTCCGGCAATCAGTACCGGCGTTTATGGCTATCCACGCGCCCAGGCCGCT
+GAAGTCGCCGTCAGGACGGTTTCAGATTTTATTACCCGTTACGCTCTGCCTGAACAGGTA
+TACTTTGTCTGTTATGATGAAGAAACTGCCCGGCTTTACGCAAGATTACTTACTCAGCAA
+GGCGACGACCCTGCCATGAAGAAACTGCCCGGCTTTACGCAAGATTACTTACTCAGCAAG
+GCGACGACCCTGCCTGATAAAACACGCCTGGAGCGTGCCGTTGAACCGCTATGCGCGCGC
+CATCCCGGAGAGTGCGGCATTCTTGCGCTGGATAACAGTCTGGACGCTTTTGCCGCCCGC
+TACCGCCTGACCGAAATGGCGGCGCGGACGCTGGATGTGCAGTATTATATTTGGGAAGAC
+GATATGTCCGGGCGGCTGCTCTTTTCGGTTCTGCTGTCGGCGGCGAAGCGCGGCGTTCAT
+GTTCGTCTGCTGCTGGATGATAACAATACGCCTGGTCTGGATGATACGTTGCGCTTGCTG
+GATAGCCATCCTAATATCGAAGTTCGTCTGTTTAATCCTTTCTCTTTTCGTACGCTACGC
+GCGCTGGGATATTTGACGGATTTTGCGCGGCTGAATCGGCGGATGCACAATAAAAGTTAC
+ACTGCCGACGGCGTAGTGACGCTGGTCGGTGGGCGCAACATCGGCGATGCCTATTTCGGC
+GCTGGCGAGGAGCCGCTATTTTCCGATCTGGACGTGATGGCCATTGGCCCGGTGGTCAAT
+GATGTCGCCAATGATTTTGAACGTTACTGGCGCTGTAGTTCAGTGTCGACATTGCAGCAA
+GTATTATCCCTTTCTGAGCAGGAACTGACGCAGCGTATCGAACTTCCCGAATCCTGGTAT
+AACGATGAGATCACCCGCCGTTATCTGCATAAGCTGGAAACCAGCCAGTTTATGGCGGAT
+CTCGATCGCGGAACGTTGCCGCTGATTTGGGCAAAAACACGCTTGCTTAGCGATGACCCT
+TCTAAAGGCGAGGGGAAGGCGCAGCGCCATTCGCTTCTTCCGCAGCGATTATTTGACGTG
+ATGGGGTCGCCGACGGAGCGTATCGACATTATTTCCGCTTACTTTGTCCCTACGCGCGCA
+GGCGTGGCGCAGTTGCTTAATCTGGTCAGGAAAGGTGTGAAGATCGCCATCTTAACTAAC
+TCTCTGGCGGCCAACGATGTGGCGGTCGTTCACGCAGGGTACGCGCGCTGGCGCAAGAAA
+TTACTGCGCTATGGCGTGGAGCTCTACGAACTGAAACCGACCCGCGAACATGAAACCGCC
+GTACATGATCGCGGACTCACCGGGAACTCAGGTTCCAGCTTACATGCTAAAACGTTCAGT
+ATTGATGGTAGTAAGGTGTTTATCGGGTCGCTTAATTTTGATCCCCGTTCAACGCTTTTA
+AATACCGAAATGGGCTTTGTCATTGAAAGTGAAACGCTGGCGACGCTTATTCATAAGCGT
+TTTACGCAGAGCCAACGCGATGCGGCCTGGCAACTGCGGCTGGATCGCTGGGGACGAATT
+AACTGGATCGATCGTCAGCAAGAAGAGGAAAAGGTGTTAAAGAAAGAACCCGCTACGCGT
+TTCTGGCAGCGAGTTCTGGTACGGTTGGCGGCAATTTTACCTGTGGAATGGTTGCTGATG
+AGCTCTGTACCCGCGCCGCGTGAATATTTTCTTGACTCTATCCGCGCATGGCTGATGTTG
+TTAGGGATTCCCTTTCATATCTCGTTGATCTATTCCACTCACAGTTGGCATGTCAATAGC
+GCCGCGCCATCGTGGTGGCTAACCCTGTTTAACGATTTTATCCACGCTTTTCGTATGCAG
+GTGTTTTTTGTTATTTCTGGTTATTTTTCGTACATGTTATTTTTACGTTATCCATTAAAA
+CACTGGTGGAAAGTACGGGTAGAACGTGTGGGTATTCCCATGCTTACCGCAATCCCTTTG
+CTTACCTTGCCGCAATTTATCCTGTTGCAATATGTCAAAGAGAAAACAGAGAACTGGCCT
+ACACTCTCTGCCTATGAAAAATATAATACGTTAGCGTGGGAACTCATTTCACATCTGTGG
+TTTTTACTGGTGCTGGTGATATTAACCACCGTCAGCATCGGGATTTTTACCTGGTTCCAA
+AAAAGGCAGGAAACAAGCAAGCCTCGTCCCGCCGCTATTTCGCTGGCCAAACTTTCGCTT
+ATTTTTTTCCTGCTGGGGGTGGCGTACGCTGCTATCAGGCGCATTATATTCATCGTATAT
+CCGGCAATCCTCAGTGACGGCATGTTCAATTTTATTGTGATGCAAACGCTATTTTATGTG
+CCGTTTTTTATTCTCGGCGCGTTGGCCTTCATTCACCCCGATCTGAAAGCGCGCTTCACC
+ACGCCCTCACGCGGATGCACTTTAGGCGCTGCCGTTGCTTTTATCGCGTATCTGCTGAAT
+CAACGTTATGGGAGCGGCGACGCCTGGATGTACGAAACCGAATCCGTGATTACGATGGTA
+ATGGGGCTATGGATGGTGAACGTGGTATTTTCACTGGGGCATCGCTTGTTAAACTTTCAG
+TCCGCGCGTGTCACCTATTTCGTGAATGCTTCGCTGTTTATTTATCTGGTGCATCATCCC
+TTAACGCTTTTCTTTGGCGCGTATATTACACCGCATATCTCCTCCAACCTGATCGGGTTC
+TTGTGCGGGCTGATATTTGTTATGGGTATTGCGTTAATTCTGTATGAAATTCATTTACGC
+ATCCCGCTCCTGAAATTTCTCTTTTCAGGTAAACCGCCGGTAAAACAAGAAAGCCGCGCC
+GCGATCGGGATGAAACATAAACGACAAATGATGAAAATGCGTTGGTTGGGCGCAGCTATT
+ATGTTAACGCTCTACGCATCATCGAGCTGGGCGTTCAGTATTGATGACGTGGCAAAACAA
+GCTCAATCTTTAGCCGGGAAAGGCTATGAGGCGCCTAAAAGCAACTTGCCCTCCGTTTTC
+CGCGACATGAAATATGCGGATTATCAGCAGATCCAGTTTAACAGCGATAAAGCCTACTGG
+AACAACTTAAAGACCCCTTTTAAGCTCGAATTTTACCATCAGGGGATGTACTTCGATACG
+CCGGTCAAGATTAACGAAGTGACGGCGACGACGGTCAAAAGAATCAAATACAGCCCGGAT
+TACTTCAATTTTGGCAATGTTCAGCACGATAAAGACACGGTAAAAGATTTAGGCTTCGCC
+GGGTTCAAAGTCCTGTACCCCATTAACAGTAAAGATAAGAACGACGAAATCGTCAGTATG
+CTTGGCGCCAGCTATTTCCGCGTTATCGGCGCAGGCCAGGTGTATGGCTTATCTGCGCGC
+GGCCTGGCGATTGATACCGCCTTACCATCTGGTGAAGAGTTTCCCCGCTTTCGCGAGTTC
+TGGATTGAGCGTCCAAAACCCACCGATAAGCGTTTGACCGTCTATGCATTACTGGATTCT
+CCGCGCGCGACCGGCGCTTACCGTTTTGTGATCATTCCTGGCCGCGATACCGTGGTGGAC
+GTGCAGTCAAAAGTCTATCTGCGCGATAAGGTGGGCAAGCTGGGCGTTGCGCCATTAACC
+AGTATGTTCCTGTTTGGGCCAAACCAGCCGTCGCCGACGACCAACTATCGTCCGGAATTG
+CATGACTCGAACGGCTTATCCATTCATGCGGGTAATGGCGAGTGGATTTGGCGTCCGCTG
+AACAATCCAAAACACCTCGCTGTGAGCAGCTATGCGATGGAAAACCCTCAGGGATTCGGC
+CTGTTGCAGCGTGGTCGCGAGTTCTCGCGCTTTGAAGATTTAGACGATCGCTATGACCTG
+CGTCCAAGCGCCTGGATTACCCCGAAAGGCGACTGGGGCAAAGGTAAGGTTGAACTGGTT
+GAAATTCCGACCAATGATGAAACCAACGATAACATCGTCGCTTACTGGACTCCGGATCAA
+CTGCCGGAACCGGGTAAAGAGATGAACTTCAAGTACACTCTGACCTTCAGCCGCGATGAA
+GATAAACTTCATGCGCCGGATAATGCCTGGGTGCTGCAAACACGCCGCTCAACGGGCGAC
+GTTAAACAGTCGAATCTGATTCGCCAGCCCGACGGCACTATTGCCTTTGTGGTGGATTTC
+GTTGGCGCCGACATGAAAAAACTGCCGCCGGATACGCCCGTCGCTGCACAAACCAGCATT
+GGCGATAACGGTGAAATCGTTGACAGTAATGTACGCTATAACCCAGTCACTAAAGGCTGG
+CGTTTAATGCTGCGCGTGAAAGTCAAAGACGCGAAGAAAACCACGGAAATGCGTGCCGCA
+TTGGTGAATGCCGATCAGACGCTAAGTGAAACCTGGAGCTACCAGTTACCTGCCAATGAA
+ATGAATAAAACAACTGAGTATATTGACGCACTGCTGCTTTCTGAACGTGAGAAAGCGGCA
+TTGCCGAAAACTGACATCCGCGCCGTGCATCAGGCGCTGGATGCCGAGCATCGGACTTAC
+TCGCGAGAAGACGATTCACCGCAGGGTTCCGTAAAAGCCCGCCTTGAACACGCCTGGCCG
+GATTCATTGGCGAAGGGGCAGTTAATTAAAGATGATGAAGGGCGCGATCAGTTGCAGGCT
+ATGCCAAAAGCGACGCGCTCTTCGATGTTTCCTGATCCCTGGCGAACCAACCCGGTTGGC
+CGTTTCTGGGATCGCCTGCGTGGGCGGGATGTTACGCCGCGCTATGTTTCTCGTCTGACA
+AAAGAAGAGCAGGCGAGTGAGCAAAAATGGCGTACCGTCGGCACTATACGCCGCTATATT
+TTGTTAATTTTGACTCTGGCGCAAACCGTCGTTGCGACCTGGTATATGAAGACCATTCTG
+CCCTATCAGGGATGGGCGCTCATCAATCCTATTGATATGGTGGGGCAGGATATTTGGGTC
+TCCTTTATGCAGCTCCTGCCCTACATGCTGCATACCGGTATCCTGATTTTGTTTGCCGTG
+CTGTTCTGCTGGGTGTCTGCCGGATTCTGGACTGCGCTGATGGGCTTCCTGCAACTGCTT
+ATCGGGCGCGATAAGTACAGTATCTCCGCGTCTACGGTTGGCGATGAGCCCCTCAATCCG
+GAACACCAGACGGCGCTGATCATGCCTATCTGTAATGAAGACGTTAGCCGCGTTTTCGCC
+GGTCTGCGCGCGACCTGGGAGTCCGTTAAAGCTACAGGCAACGCCGCGCATTTTGACGTC
+TATATCCTTAGCGATAGTTATAACCCGGATATTTGCGTGGCGGAGCAAAAGGCGTGGATG
+GAGCTCATCGCGGAAGTGCAGGGCGAAGGCCATATTTTTTACCGTCGCCGCCGCCGCCGT
+ATGAAACGCAAAAGCGGCAATATTGACGATTTTTGCCGCCGCTGGGGCAATCAGTACAGC
+TATATGGTGGTGCTGGACGCGGACTCAGTGATTAGCGGCGAGTGTCTGAGCGGGCTGGTG
+CGCCTGATGGAAGCGAACCCTAACGCCGGGATTATCCAGTCTTCGCCGAAAGCGTCGGGG
+ATGGATACTCTGTATGCCCGCTGCCAACAGTTTGCGACCCGTGTTTATGGACCGCTGTTT
+ACCGCCGGGCTGCACTTCTGGCAGTTGGGGGATTCGCACTACTGGGGGCACAATGCCATT
+ATCCGCGTGAAGCCGTTTATCGAGCACTGCGCTCTGGCGCCGCTGCCGGGAGAAGGTTCG
+TTCGCCGGATCGATTCTTTCCCACGACTTTGTTGAGGCGGCGCTAATGCGTCGGGCAGGG
+TGGGGCGTCTGGATTGCCTACGATCTCCCCGGTTCCTATGAAGAGCTGCCGCCAAACCTG
+CTGGATGAGCTTAAACGCGACCGCCGCTGGTGTCACGGCAACCTGATGAACTTTCGTCTG
+TTCCTGGTGAAAGGAATGCACCCGGTGCATCGTGCCGTGTTCCTGACCGGGGTAATGTCA
+TACCTGTCCGCGCCGTTATGGTTTATGTTCCTTGCGCTTTCTACCGCGCTGCAGGTCGTT
+CATGCGTTAACAGAGCCGCAATATTTCCTTCATCCGCGCCAGCTTTTTCCGGTCTGGCCG
+CAGTGGCGTCCGGAACTGGCAATCGCGCTGTTTGCGTCAACGATGGTGCTGCTGTTCCTG
+CCGAAGCTGCTCAGTATTATGCTGATCTGGTGTAAAGGCACCAAAGAGTATGGCGGTTTC
+TGGCGCGTTACGCTGTCGCTATTGCTGGAAGTTCTGTTCTCCGTGTTGCTGGCGCCGGTG
+CGTATGCTGTTTCATACCGTGTTTGTGGTCAGTGCGTTCCTCGGCTGGGAAGTGGTCTGG
+AACTCACCGCAACGCGACGATGATTCTACGCCTTGGGGAGAAGCCTTTATGCGTCACGGC
+TCTCAACTGCTGCTGGGGCTGGTCTGGGCGGTTGGTATGGCGTGGCTGGATTTACGCTTT
+CTGTTCTGGCTGGCGCCGATTGTCTTTTCGCTTATTCTGTCGCCATTTGTTTCGGTGATC
+TCCAGTCGTTCAACGGTAGGATTACGCACCAATCGCTGGAAGCTGTTCCTGATCCCGGAA
+GAGTATTCGCCGCCTCAGGTGTTGGTCGATACTGATAAATATCTGGAGATGAATCGCCGC
+CGTATTCTGGACGATGGCTTTATGCATGCGGTTTTTAACCCGTCGCTTAATGCGCTGGCG
+ACCGCGATGGCCACCGCGCGTCACCGCGCCAGTAAGGTGCTGGAAATAGCCCGCGATCGT
+CATGTGGAGCAGGCGCTAAACGAAACGCCGGATAAACTGAACCGCGATCGGCGTCTGGTT
+TTGCTCAGCGATCCGGTGACGATGGCGCGTTTTCACTATCGGGTCTGGAATGCGCCAGAG
+AGATACTCTTCCTGGGTAAACCATTATCAGTCTCTCGTCCTGAATCCGCAGGCGTTGCAG
+GGACGAACATCGTCAGCGGGAGTGCGTATATTCGCGGTGAGCATAATGGTGATTACCCTG
+AGCGGCTGCGGCAGTATTATCAGCAGAACGATCCCCGGACAAGGACACGGCAACCAGTAT
+TACCCTGGCGTGCAGTTGGATATGCGTGATTCCGCATGGCGCTATATCACTATCCTCGAT
+CTGCCCTTCTCACTGATCTTCGATACACTGCTACTGCCGCTCGATATTCACCACGGGCCT
+TATGAGATGAAAAAAAACCTGCTGGGATTCACCCTCGCATCCTTGTTATTCACGACCGGT
+TCCGCCGTGGCGGCGGAGTATAAAATTGATAAAGAAGGCCAACATGCGTTCGTCAATTTC
+CGCATCCAGCATCTGGGCTACAGCTGGCTATACGGCACCTTTAAAGATTTCGACGGCACG
+TTCACTTTTGACGAAAAAAATCCGTCAGCAGACAAAGTGAATGTGACCATTAACACCAAT
+AGCGTCGACACTAACCATGCCGAACGTGACAAACACCTGCGTAGCGCGGAGTTTCTTAAT
+GTTGCGAAATTCCCGCAGGCAACCTTCACCTCTACCAGCGTGAAAAAAGAGGGCGATGAA
+CTGGATATTACCGGCAATCTGACGCTCAATGGCGTGACTAAACCGGTGACGCTGGAAGCG
+AAGCTGATGGGCCAGGGCGACGATCCGTGGGGCGGTAAGCGCGCGGGCTTTGAGGCCGAA
+GGAAAAATTAAGCTGAAAGATTTCAATATAACTACCGATCTCGGCCCAGCCTCACAAGAG
+GTGGAGCTTATCATCTCAGTAGAAGGCGTTCAGCAGAAGATGTTACTGATGATGGCGCTG
+ATCGTGCGTATTATCTGGCGGCTTTATTCTCCGCCGCCCGTTGCGTTGACCAGCTATTCC
+CGTTTAACGCGCATTGGCGCCGCCGCGGGTCATATCCTTCTGTATCTCCTGCTCTTTGCG
+ATAATCATTAGCGGCTACCTGATTTCCACCGCCGACGGTAAACCGATTAGCGTCTTTGGC
+TGGTTTGAGATTCCGGCCACGCTTACGGACGCGGGCGCGCAGGCTGACATCGCCGGAACA
+CTGCATCTGTGGTTTGCCTGGTCGCTGGTCATTATCTCGCTCTCGCATGGGGTTATGGCG
+CTAAAACACCATTTCATCGATAAAGACGACACACTGAAACGTATGACAGGAATGTCGTCA
+TCTGACTATGGAGCTCAAAAAATGAAATACGACCTTATTATTATCGGCAGCGGTTCGGTT
+GGCGCCGCCGCTGGTTATTACGCCACCCGCGCCGGGCTAAAGGTCCTGATGACCGATGCG
+CATATGCCGCCTTATCAACAGGGCAGCCACCACGGCGATACCCGTCTTATCCGCCACGCT
+TATGGTGAAGGCGAAAAATATGTCCCGCTGGTGCTTCGCGCCCAGACGCTTTGGGATGAG
+CTCTCCACACACAATGAAGAGCCTATTTTTGTCCGCTCCGGCGTCGTCAACCTCGGCCCG
+GCCGATTCCGCTTTCTTAGCCAACGTCGCACGAAGCGCGCAACAGTGGCAATTGAACGTC
+GAGCGCCTGGACGCGACGGCCCTCATGACGCGCTGGCCGGAAATTCGCGTGCCCGATAAT
+TATATCGGGCTGTTTGAAGCTGACTCCGGTTTCCTGCGCAGCGAATTAGCCATTACCACA
+TGGCTTCGTCTGGCCCGAGAGGCAGGCTGCGCACAGCTATTCAACAGCCCGGTAAGCCAT
+ATTCACCATGATGATAACGGTGTGACGATAGAGACGAGTGAAGGCTGCTACCACGCCAGC
+AAAGCGCTGATTAGCGCGGGCACCTGGGTCAAAACGCTGGTACCGGAGCTGCCCGTTCAG
+CCCGTACGTAAAGTTTTTGCCTGGTTTAAGGCGGATGGACGTTACAGCACTAAAAACCGC
+TTTCCGGCCTTTACCGGCGAAATGCCCAACGGCGATCACTATTACGGTTTCCCGGCGGAG
+AACGACGAGTTAAAAATCGGCAAACACAATGGCGGGCAGCGAATACAGGCACCGGAAGAG
+CGCAAGCCCTTTGCCGCCGTTGCCAGCGATGGCGCGGAAGCATTTCCTTTCCTGCGTAAC
+GTACTGCCGGGTATCGGCGGTTGTTTACATGGGGCGGCATGTACCTATGATAATTCGCCG
+GACGAGGATTTTATTATCGATACGCTGCCTGGCCATGAGAATACGCTTGTCATCACTGGA
+CTCAGCGGACATGGTTTTAAATTCGCCCCGGTGTTAGGAGAAATCGCTGCGGATTTTGCG
+TTGGGAAAAACGCCCTCCTTTGATCTGACGCCGTTCCGGCTTTCCCGTTTTAGCCAAATG
+GAAAAGAATAATGAAGTCATTCAGACCCATCCGCTTGTAGGATGGGACATCAGCACCGTC
+GATAGCTATGATGCGCTGATGCTGCGTTTACACTACCAGACCCCAAATCGTCCGGAACCG
+GAAGGGACTGAAGTTGGTCAAACGCTCTGGTTAACGACAGATGTAGCCAGGCAATTTATT
+TCAATATTAGAAGCCGGCATCGCCAAAATAGAATCAGGCGATTACCAGGAAAACGAGTAT
+CGTCACCAT
diff --git a/t/data/reformat_input_gffs/expected_fixed_query_2.gff b/t/data/reformat_input_gffs/expected_fixed_query_2.gff
new file mode 100644
index 0000000..1cabef6
--- /dev/null
+++ b/t/data/reformat_input_gffs/expected_fixed_query_2.gff
@@ -0,0 +1,220 @@
+##gff-version 3
+##sequence-region abc|SC|contig000001 1 15000
+abc|SC|contig000001 Prodigal:2.60 CDS 172 1131 . - 0 ID=1_1___1;gene=different;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:Q2G1X0,protein motif:TIGRFAMs:TIGR01002,protein motif:Pfam:PF07968.6;locus_tag=abc_00001;product=Alpha-toxin,beta-channel forming cytolysin,Leukocidin/Hemolysin toxin family protein;protein_id=gnl|SC|abc_00001
+abc|SC|contig000001 Prodigal:2.60 CDS 1804 1950 . + 0 ID=abc_00002___2;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00002;product=hypothetical protein;protein_id=gnl|SC|abc_00002
+abc|SC|contig000001 Prodigal:2.60 CDS 1934 2131 . + 0 inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00003;ID=abc_00003___3;product=hypothetical protein;protein_id=gnl|SC|abc_00003
+abc|SC|contig000001 Prodigal:2.60 CDS 2621 3337 . - 0 ID=abc_00004___4;inference=ab initio prediction:Prodigal:2.60,protein motif:CLUSTERS:PRK13350,protein motif:Pfam:PF02876.11;locus_tag=abc_00004;product=superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00004
+abc|SC|contig000001 Prodigal:2.60 CDS 3445 4170 . - 0 gene=speH;ID=1_2___5;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P0C0I6,protein motif:CLUSTERS:PRK13349,protein motif:Pfam:PF02876.11;locus_tag=abc_00005;note=SPE H;product=hypothetical protein,superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00005
+##FASTA
+>abc|SC|contig000001
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
+ATACCCACCACATTTGGTGGAGAACCAAAAATTAGCCGAAAAACATCATTTCTGAAGTTA
+TCGGCTAAAGTTATAAATTATATTTATTTGTACATGAACAAATAATTTACATTAATTTGT
+CATTTCTTCTTTTTCCCAATCGATTTTATATCTTTCTGAAGAACGATCTGTCCATTTATC
+TTTAGTATTGGTACCTTTCCAATTTGTTGAAGTCCAATGCAATTGGTAGTCATCACGAAC
+TCGTTCGTATATTACATCTATATTTGTTTGTTGTTTGGATGCTTTTCTATCCATAGTAAT
+AACTGTAGCGAAGTCTGGTGAAAACCCTGAAGATAATAGAGAACTTGCTTTGTTAGGATC
+AAGGAAGTTCTCTGCTGCTTTCATAGAACCATTTCTAGTTTTCATGAAAAGTTGATTGCC
+ATATACCGGGTTCCAAGAATCTCTATCATATGGTCCCCAATTTTGATTCACCATATTGTT
+AAATATCACTTTCCAGCCTACTTTTTTATCAGTTGGGCTCTCTAAAATTGTTTTGAAATC
+AGGTTGAACATATTTCAGTGTATGACCAATCGAAACATTTGCACCAATAAGGCCGCCAAT
+TTTTCCTGTATCATCACCAGTAACATTACCGTTGAATCCATAAGTTAAAGTACTCATATA
+CTCTTTTGTATCAATCGAATTTCTTGGATAGTAATCAGATATTTGAGCTACTTCATTATC
+AGGTAGTTGCAACTGTACCTTAAAGGCTGAAGGCCAGGCTAAACCACTTTTGTTAGCACC
+TTCTTCGCTATAAACTCTATATTGACCAGCAATGGTACCTTTCGTTCTAATAACTAGCAG
+TTTTTTATTGTGATTTTTATCATCGATAAAACTATAAAATACTTTTTTGTGCATGCCATT
+TTCTTTATCATAAGTGACTAAATCACCTGTTTTTACTGTAGTATTGCTTCCAATATCTGT
+AGTACCGGTTTTAATATTAATATCAGAATCTGCGGCATTAGCGACAGGATTCATTAATAT
+GGAACCTAGCAATAGTGTTGTTGTTACTGAGCTGACTATACGTGTTTTCATTTTCATCAT
+CCTTCTATTTTTTTTAACGATTTGAGGAAACAATAATCAATATGTCAATTTAGAATATTG
+CAGTTGAGACATATCAAATATTTATAATCGTTTATATTAGTATATTTAATGTAGCAACTG
+ATAAATTACTGAGTGATGATGAGTGATTATTTTAAGAATATGTTTTTAACTTTTATTTAA
+AATTTGAAAGGAAGCATTTCAATTTCGAGGGTTAGTCAAAGTTGAATAAATTCTTTATGA
+AACAAGGAAAAGACATAGCTAATTTTATTGATTAATTTCTTTAAAACTAATGATTTGTTT
+GATTTAAAAATGTAATCGATTACAATATAAAAATACAAATATCTTAGAATTAAATCAATT
+AATTAACTATTAAATAAAAATTAAATATATATTAACTACTGTAAATTAATAAATAGAAAT
+AGAGAAAAAGGGTATTAATTATGTTTGGAATTTCGTCGGGAATAATTTTTGCCATTACAT
+AGAAATATCTAATAGATAATGAAAAAGTATCGTATGTATTTTTAATATAGTGTAAAATAT
+CATATGTAAAATAAAATGTAGATTTTTAGTTAGAGGCATTATAAGAAAATTTTGAGTATA
+GGTTAGCTTTTAATTATGAATCTTATTGAAATTTGATTAATAAATATATGATAGGGGATT
+AAAATGAAACTATTTTATATCGTATTTCTTATTATTATATGGCTGAATATATTTTTAGGA
+AATGAAATTATCCATACACTGACTGTTTTAATAACAACATTGTATATTGTTAATTCAAGA
+AAGGGGATTAAAAATGACAGAGTTGAATAATATTATAAACTCTCTTCAATCTTTGTTTGA
+GTCTGAATCAGGCTATAAAATTTCGAAAAATTCAGGAGTTCCATATCAAACAGTACAAGA
+TTTAAGAAATGGGAAAACCAAACTAGAAGATGCTAGATTTAGAACGATTATTAAACTTTA
+TAGTTACTATGTCTCATTAAAAGAACATTAATCATGGGACAATAAAGTATTGCTATAATA
+ATTGAATCATTAAATGAAGGAATAGAGCCTAAGACATAATAAATCAATGTCTTAGGCTCT
+ACAATATTATATTGGTAGTAGTTGACCGAATGAAAATGACCATGTAACAAGCATTTTTGG
+GGCCCCAACACAGAAGCTGACGAAAAGTCAGCTTACAATAATGTGCAAGTTGGGGATGGG
+CCCCAACACAGAGAATTTCAAAAAGAAATTCTACAGACAATGCAAGTTGGCGGGGCCCCA
+ACATAGAGAAATTCAAAAAGAAATTCTACAGACAATGCAAGTTGGGGAGTGACAACGAAA
+TAAATTTTATAAAATACCATTTCTGTCACATTCCTACTCCCAATTCCATTTAAATATATA
+GAAAATTTCACCTATTATATACATCATACACTTTAAAAATTATCATTTAAATAATCTGAT
+TTGGAATTAAAGTGCATGAAGTATAAGTCACCTTCATATACTAATCAAAGAGGACGTCAA
+CAGTTATTTTATTAGGATTTTTAACATAAACATTTGCTAGATCTGAATGTAATCTTTTGC
+TTAAATCAATAGTGTAGTTATTACCGCCACCGGTGATCTTAAGCTTACCTTTATTACGAT
+TTTCGGTATATAATATTTTATTTTTTATTAACGCTTCTCGTGCACGGAAATCGATTTCTT
+TCAATGTTAATACTGGTTTATTGCCTTGGTATATTTTATGCGCACCAATAATCGTTTGTA
+GTTTATCTTTGTATTGCACAAAAAGATTATAAGTTTTATCAGAAGGTTTTGCGGCTGGTG
+TAACGCCACCTGTAAATGTCTCTCTATAAGACCACCATAACTGATCAGTATCTTTGTCTT
+TTAGTCCAAACACATCTACGTAACGATCTTTTAACTGATTAATATTTCCCCAACTTTCAG
+CGCCCCATAAAGATATATGTGCTGACCATGAATATCTCTTAAGTTCAACATAAATGTTTC
+CATTATCATATTGATATAGCCATTTATTTGAAAATGAAAAATGAGGCTGTGTGTAATATT
+TAATTAATTCATTGATGTTAGTTTCATCTTGACCAATGCTATAAGCTTTAGCTTCAGAGT
+AAAAACTAAATACTGGTTTTTGATTTTGAGGTAATACAGTACCTAATAGTAATAATGTTG
+TCGTTAAAATTATATTTTTCGTGATGTTCTTACTCATTAGAACATCTCCTTTCAGAGGAA
+TCATGATACGAGGAATAAGAAATTTAAATGTGAGCGAAGTCAATATAGTATTTGCGATTA
+TTTTTATTAACTCCATTATTATTGTTAGTTTGATTTTTCGAGGATAACTTCAATTTTTGC
+ATTTTGAGGTTTTTTAACATATCTATTTGCATCAGTTGATGGCAACCTTTTACTTAAATC
+TATTGTGTAGTTATTGTCTGTACCTGTTATTTTAATTTGTCCTTTATTATAAGAATTATT
+ATATAATTTTTTACTTTTAATTAATGTTTGACGAATACGAAAATCTAATTCTTTTAAAGT
+TAAAACAGGCTTATTGCCTTCATAAACTGGAAATCCGCCAGTAAACGTTTCTGCTTTATC
+TTTATATGTTACATTCAGTTTATAGTGTTTATCGTTAGATGTTGCTGCAGGAGTAACACC
+ACCAGTAAACGTTTCTTGAGATAATGCAAAAGAATCAATGGTTTCTTGGTCTTTTATGCC
+AAAAATATCAACGCTTTTATTTCTTAATTGGTTGATATTGCCCCAACTTTCAGGTCCATA
+AACTTGAATATGACTATACCAAGAAAACTGTAACAACGTTGCATGAATCGTACCGTTATC
+TTTTTGCCATAACGTACTGTTAGAGAAGGTTAAATATTTTTGCGAGTAATATTTAGTTAA
+CTCATTAACGTTAGTTTCGTTTTGATTTATATAATAAGCTTTCGCTTCAGATGAAGAATT
+GATAGGTGTATTAGGAAATTGTGTAAATGCTGTACCTAATAGTAACAATGTTGTTGATAA
+AATAATTTTTTTCGTGATGTTATTGTTCATTCGAATTTCTCCTTTGAGTATTGTTGGAAT
+GTTTAATTATAAAAAGGGGTTAATTAGATAATTGAAATTATCCGCATTTACAAAAGGTAA
+TAGGTTAGTTAGATTTTTCGAGTATGACTTCAATTTGTGCATTTTTAGGATTTTTAACAT
+AACGGTTTGTGTCAGTTAATTTTAACTTTTTACTTAAATCAATCGTGTAATTATTTCCAT
+CAGCAGTTATCTTAATTTGACCTTTATTAAATTCTCCGTTATATAACTTTTTATTCTTTA
+TTAATGTTTGACGAATACGGAAATCTAATTCTTTTAAAGTTAATACTGGTTTATTTCCTT
+TGTAAAATTCATGTCCACCGATGATAGTTTGTTGTTTATCACTATATTTTAAAAATAGTC
+TATAAGGTTTATCAGATGAAGTAGCTGCTGGCGTAACACCACCAGTAAATGTTTCATCAT
+AAGTCCAGTAACCTTCAACTGTGTCCTCATCTTTAGTTCCAAATATATCAACGTATTTAT
+TTCTTAACTGATTAATGTTTCCCCAACTCTCGGATCCAAACACTTGAATATGACTATACC
+AAACCCACGTTTGCAATGTTGCATGAATGCTACCATTGGGCTTTTGCCATAGCCATTTTC
+CAGATAATGAAAAATGCGGCTGAGTGTAATATTTGATTAACTCATTGATATTAGTCTCGT
+TTTCACTGATATTATAGGCTTTTGCTTCAGATGAAAAACTGATTGGTGTTTTAGGAAGTT
+GTGTTGATGTGGTTCCTAAAAGTAACAATGCTGTTGATAAAACTAATTTATTCATGATGT
+TCTTTTTCATATGAAAATCTCCTTTGCGTGAATTACCCAAAGTATATAAGCTATTACACC
+GATTCGGAATTAAATAAAAGCTAAAACTATGTTAAATAAACTTAAACAGTTAGTAGTGTT
+ATTTAAGCAAAACTTATCATTTTTAAGTTTTGGACAGAAACAGTACTTAATAAAGTAGGC
+GGGAGTTATATATTAAAAACGACACGTTACAATTATTCTCTAATCAATTGCATTAAATTG
+TTTGATAATTGAATTTTCTAACTACTTGAAAAATAGTTATACTTTAAATGTAGTACTTAT
+TTTAATTATTTCCTACTACTTAAATTTAATATTAATAAAATGTTCATTTAATTATTGATA
+AAATATTACAAATTTTAATAGTAGGTTGTGTTTATTTTGTATGCGCTTACAATTTAGGTG
+TAACTAAAATAAAAGGAGTTGTTATTAATGAAAAATTTACGAAACAGAAGTTTTTTAACT
+TTATTAGACTTTTCACGACAAGAGGTAGAATTCTTATTAACACTCTCCGAGGATTTAAAA
+CGTGCTAAATATATTGGCACTGAAAAGCCTATGTTAAAAAATAAAAATATTGCACTGTTA
+TTTGAAAAAGATTCTACAAGAACGCGATGTGCATTTGAAGTTGCAGCGCATGATCAAGGT
+GCAAATGTAACTTATTTAGGCCCAACTGGATCACAAATGGGTAAAAAAGAAACAACTAAA
+GATACTGCACGTGTGCTTGGTGGAATGTATGATGGCATTGAATACCGTGGTTTTTCACAA
+AGAACAGTAGAAACTTTAGCTGAAAATTCAGGCGTACCAGTGTGGAATGGTTTAACTGAT
+GAAGATCATCCTACTCAAGTTCTTGCTGATTTCTTAACAGCAAAAGAAGTCTTAAAAAAA
+GATTATGCAGATATTAACTTTACATATGTTGGAGATGGTCGTAATAACGTTGCAAATGCA
+TTAATGCAAGGTGCTGCCATTATGGGTATGAACTTCCATTTAGTTTGTCCAAAAGAATTA
+AATCCAACAGATGAATTATTAAATCGCTGTAAAAATATTGCCGCTGAAAATGGTGGCAAC
+ATATTAATCACAGATGATATTGACCAAGGTGTAAAAGGTTCGGATGTAATTTACACTGAT
+GTTTGGGTATCAATGGGTGAACCTGATGAAGTATGGAAAGAACGACTTGAATTATTGAAA
+CCATATCAAGTAAATAAAGAAATGATGGATAAAACTGGTAATCCAAATGTTATTTTTGAG
+CATTGCTTACCATCTTTCCATAATGCTGATACGAAAATTGGTCAACAAATTTTTGAAAAA
+TATGGTATTCGAGAAATGGAAGTTACAGATGAAGTATTCGAAAGTAAAGCTTCAGTTGTA
+TTCCAAGAAGCTGAGAACAGAATGCATACAATCAAAGCAGTCATGGTTGCTACATTGGGT
+GAATTTTAAATGATATAAGGAAGTGAATATGATGGCGAAAATAGTAGTAGCATTAGGTGG
+TAATGCTTTAGGAAAATCACCTCAAGAACAACTCGAGCTTGTTAAAAATACTGCGAAATC
+ATTAGTAGGATTAATAACAAAAGGACATGAGATTGTTATTAGTCATGGTAATGGACCACA
+GGTTGGAAGCATTAATTTGGGACTTAACTATGCTGCAGAACATAACCAAGGTCCGGCATT
+TCCATTTGCTGAATGTGGCGCAATGAGTCAAGCTTACATCGGCTATCAATTACAAGAAAG
+CTTACAAAATGAATTGCATTCTATTGGAATGGATAAACAAGTGGTAACACTAGTGACACA
+AGTTGAAGTTGATGAAAATGATCCGGCATTTAACAATCCTTCAAAACCAATTGGGTTATT
+TTACAACAAAGAAGAAGCTGAACAAATTCAAAAAGAAAAAGGATTTATATTTGTTGAAGA
+TGCTGGAAGAGGATATAGACGCGTTGTTCCTTCACCACAACCCATCTCTATTATTGAATT
+AGAGAGTATTAAAACACTTATTAAAAATGATACACTCGTTATTGCTGCTGGTGGTGGAGG
+TATACCAGTAATTAGAGAGCAACATGATGGTTTTAAAGGTATTGATGCAGTTATAGACAA
+AGATAAAACAAGTGCGTTGTTGGGTGCTAATATTCAATGCGATCAATTGATTATTTTAAC
+AGCAATTGATTATGTATATATTAATTTTAACACTGAAAACCAACAGCCTTTGAAAACAAC
+AAATGTTGATGAATTAAAACGATATATAGACGAAAATCAATTTGCAAAAGGAAGTATGTT
+ACCAAAAATTGAAGCAGCCATATCATTTATTGAAAACAATCCAAAAGGAAGTGTGCTTAT
+AACATCATTAAATGAATTAGATGCTGCCTTAGAGGGTAAAGTAGGTACTGTGATTAAAAA
+GTAATTGAATTGAAACGCTTTTCAATTACTATATGTCAAATGCATGATTTTTATTATTTA
+TGTGCACCCCCTGAAAATAATGCCTCTATTTTGATGCGGGGTGCACTTTCTTAATTTATA
+TTTATAAAATCTTTAAGGTAGAAATGCTAGGTTAAATGTCGAAGGAGATGAAACCGTGGA
+AAATACAATTAATGAAAGTGAAAAGAAAAAACGATTTAAATTAAAAATGCCAGGTGCATT
+TATGATTTTATTCATTTTAACGGTTGTTGCAGTTATAGCAACATGGGTTATTCCTGCTGG
+TGCATATTCTAAACTTTCTTACGAACCTTCATCCCAAGAACTAAAGATAGTTAACCCTCA
+TAACCAAGTGAAAAAGGTTCCGGGTACGCAACAGGAACTAGACAAAATGGGGGTTAAAAT
+TAAGATTGAACAATTTAAATCAGGTGCAATTAATAAGCCAGTATCAATTCCGAATACTTA
+TGAAAGATTAAAGCAACATCCAGCTGGACCAGAACAAATAACAAGTAGCATGGTTGAAGG
+TACGATAGAAGCGGTCGATATCATGGTATTCATTCTTGTACTAGGGGGACTTATTGGCGT
+AGTTCAAGCCAGTGGTTCTTTTGAATCGGGATTGTTAGCTTTAACGAAGAAAACAAAAGG
+GCATGAATTTATGCTAATTGTGTTTGTATCAATACTAATGATTATCGGCGGGACGTTATG
+TGGTATTGAAGAAGAAGCTGTAGCATTCTATCCGATTTTAGTCCCTATATTTATAGCGTT
+AGGATACGATTCTATCGTTTCAGTTGGTGCCATATTCCTTGCCAGCTCTGTCGGTAGTAC
+ATTTTCAACTATTAACCCGTTCTCGGTTGTAATTGCCTCTAATGCCGCTGGTACAACTTT
+TACGGATGGCTTGTATTGGAGAATAGGTGCTTGTATTGTCGGTGCGATTTTTGTTATTAG
+TTATTTATATTGGTACTGTAAAAAAATTAAAAACGATCCTAAAGCGTCATATTCTTATGA
+AGACAAAGATGCTTTTGAACAGCAATGGTCTGTATTAAAAGATGACGATAGTGCCCATTT
+TACTTTGCGTAAGAAGATAATCCTTACATTATTTGTACTACCATTTCCAATTATGGTATG
+GGGAGTTATGACGCAAGGTTGGTGGTTCCCAGTTATGGCTTCAGCATTTTTAATATTTAC
+AATTATAATAATGTTTATTGCTGGGACAGGTAAATCTGGATTGGGAGAAAAAGGAACTGT
+AGATGCATTTGTCAATGGTGCATCAAGTTTAGTAGGTGTATCTTTAATTATTGGTTTAGC
+TCGAGGTATTAATTTAGTGTTGAATGAAGGTATGATTTCAGATACAATCTTACACTTTTC
+ATCATCTTTAGTTCAACATATGAGTGGACCATTATTTATCATCGTATTACTATTTATTTT
+CTTCTGTTTAGGTTTTATCGTGCCATCATCTTCTGGATTAGCGGTATTATCAATGCCTAT
+CTTTGCACCACTAGCTGATACAGTAGGTATACCAAGATTCGTCATCGTTACGACATATCA
+ATTTGGTCAATATGCGATGTTATTCTTAGCGCCGACTGGACTTGTTATGGCCACACTACA
+AATGTTAAACATGCGATATTCACATTGGTTCCGATTTGTATGGCCGGTAGTTGCTTTTGT
+ATTGATTTTCGGTGGCGGAGTACTAATTACGCAAGTACTAATTTATTCATAATTTGAAAT
+GCTATATTATAAAAATACTAATTGGGTTTTATGCATCTCGTAGGTTTGTAGAAATACTAA
+ACTAAGCGAGGTGCATTATTATTTTTGATTAAGAAAATAATGACGGTAATGATAACACTA
+GTAAGTAATTGATACAATGCTCTATTTAATAATGATATTTTTAAAATTTGTTTTTAATGT
+AATGTTAGATCTATGGTATATTATATTTATCGTGGTAAATATGTATTTGCTGTAAACAGT
+TTTTGTAACACATGACACATATGGTTGTGAAAATAGCATATATAAAGGATGGCTATAAAT
+GACACATTTGACAAAGGTTTTAGATACACTAACTGGAATATGCGTAGTATTATTATTTAG
+TAAATATTTTGTGGCGTATGCAAATATGGTGTTTGATTGGAATTTAAGATGGTATTTGCT
+AGAAAACATACCACATTTGCCAATTATATTATTTATTCTGATGTTTATTTTCGGAGTACC
+TTCTGAAATGATAAAAGATAGGCAAAGGAAAAATAACGGTGTTTAATTTATCGATATTTA
+GAGGTGATAAAATTTGTCAACTATTACAAAGACTAAAATAAAAATCTTTATTAATTATTT
+TATTGGTATATTAGCCTTGGCGTTTGCTGCTTATATATTATTTAAATAAAGGTTAGAGTG
+AAACGTGTTTATGAACTAGACGTTCTAGTATAGTTACTACAGCTTTAGTCAGAAGGTATC
+ATTGATAAGATCATATTAAATCAAAGAGGCATTGATATACACTAAAAAGAGGCAAGATTA
+CCTGCCTCTTTTTTAGTTATTAAATATGCGTGTTAATTCTTGGTAATAGTGTTACTGAGA
+CGCATTACGAAGAAATTTATCTTGATTTTCCTTTTTTAAAAAGAAGTGAAGATATCCTAT
+AAAGACTCTAAGTACTATTACAGTGGCTAATAACACTTCGATAAACAAAAGACCTTTCCA
+AATATCTGGAAACATAAGTACAGGCAAACTGTTCTTTAAAGCAGTTGCTGAGATTACTAA
+AGGGAATGTGAAAGCTGAAAATACGGGCGAAAAAGGTTCTTTTAGTAATTTAGGCAATTG
+TATAATGATATAAAAATAAAATATTTGAGCTAATATTAAAAATATAATTACGATAAAAGC
+ATTCGCCTTAGGAAAGGCTATAACATATGCTGCAGCGACTAAAGAAAATGGTGCACAAAT
+TGTCGATGTGTTCGGTTTGATTGACGTCTGCAATGGAAATGCTTTTAATCGCTTGAAAAC
+AATAGGTAAGACAATACAAGTAGCTACAAAGCCATATATTACTGTTAATTGACCTATGAA
+AAAACATCCGCTAACGGGTGCCGTCAATCCTGCGATAGCAATACCAATAAAAAGTACAGT
+CCACGAAGGATAAACATTTTCAAGTGAAAAATCTTTTAAATATTTTATTGAAAAAATAAT
+CATATGCGTCATAATTCCCACAAGGCATAAAATCCAAATAGGCGTTATTAAGCTATTGAT
+AAAAGTTATGTTACTAAAAAATGTATTTAAATAAGTAGTACCTAAAAAGCCAGACATGAA
+AAATGTTGTGAACACTGATGAAACTAGAGGACTGTTTAATTGTTCTTTCACATTATTAAA
+ATATTTGATCATAGTACATAAAAGGTGAATCCAAATCAAGAAAGCAAAGATTCCGCAAAC
+AGCGTTTAAAGTAAGAGATAAGTCTTTTAATAGATTACCCAGGCCTAATAATCCTAAGAC
+TAGTCCTGACGTTACTAGAGGTGCTTTTTGAAGTCTCATGATTTACAACCTTTCTTATGT
+GATTTTCTTCACTAATTATATCATGATAGCTATGGCCAATTAATAAGAAGAGTGTGTACT
+ATTACGTTATTAGAGTATGTATATTGGATTGATAGACACATAATTGACATTTAAATCTCA
+AAATTAATGATATTTGAGGTATGCTTTGCAACCTAAATATTGGAATATGTGGAAAAGTAA
+TTATTTAATTTAAATGATGATTGAAGATTTACAAGGGGGTGTACAAAATGAGAAATCAAA
+TTCAAAAACTATTAGACAGTGATTTGAGCAGTTTACATATATCGAAACAAACAGGAGTTC
+CACAAAGCACAATACACAGAATGAGAAAAAAAGAAAGATCATTAGACAATATGTCATTGA
+AAAACGCTGAACTACTTTATAAATTTGCCAATAGTATATTTAGCAATGAAAATTAAGAAG
+AATAATTAGTGAGTTAAATAATTAAAAAACCACGTCTCGATGGACGTGGTTATTTTTTTA
+AATGTATTTAATTATAGGATTTCGGGCCCCTGAAAAGTCCCTAAAATTTTGAATAGTATC
+AAAATCTATAGGAATAATATAATAATAAAAATCTCTACGCATGCAAATGGTGAGTGTTAA
+AAATCTTGGTGTAGTGTTGGTGTAGTTCAGGTGCAGTATAGATGAAATTTGAGCACAAAA
+TTACTTAATTAAAAATGTATAAACAAGTGTCAGACGCGTGTCAATTGTGTGTCAAAAAAT
+TCTATGACGAATAAGCATGCTTGTTTTAATTACTGTATTTTCGGGGCTTATGCGGGGGAC
+GTTTTGGTGACGCATCATACTATATTACTGAAATTCAAAACAAAAAGAGCCCCGTAATCA
+CGGAACTCTTTTGTTTGGTAATGCGTATAAAAATACCTATAAACGTCCTGGGAGGGATTC
+GAACCCCCGACCGATGGCTTAGAAGGCCATTGCTCTATCCAGCTGAGCTACCAGGACACG
+TTTAACAACACAAGAATTATTATATCTAAATGAACTTAAATTAGCAATACCTTGTAAATA
+AAAAATGTTTATATTTTTCACTATTATAGAGCTATTTATCTAAAAAGGTTCAATAAGACT
+TAAATGCGAATTCAGGCAACTTAATTGTGTTAAATACAGTTTTGAATGCCTAACTGTATT
+TCTTTTCTCTTTAAAATACAGTTAAGTACATTATAAGATGTTGTGCGGATAAACAAACTA
+ATTGCATCAAATTTATTTTAAAATAACAACAACAAAACGTTAAGCGAATAACATTTCGGT
+GATTTAAAAGCTACGCACGTTTTTGTTATCTTCAAATTTAAATTTTAAGGAGTGTTTTCA
+ATGGAAGGTTTATTTAACGCAATTAAAGATACCGTAACTGCAGCAATTAATAATGATGGC
+GCAAAATTAGGCACAAGCATTGTGAGCATCGTTGAAAATGGCGTAGGTTTATTAGGTAAA
+TTATTCGGATTCTAATTTCAATATGTTATGTAAGTAATCAGTATTATTTCAAAGGTGAGG
+GAGAGATTTAAATGACTGGACTAGCAGAAGCAATCGCAAATACTGTGCAAGCTGCACAAC
+AACATGATAGTGTGAAATTAGGCACAAGTATCGTAGACATCGTTGCTAACGGTGTGGGTT
+TACTAGGTAAATTATTTGGATTCTAATATAATAACTAATATTCTTTAAAATAAACTGGGT
+GAGCATACTTTAATGTTATGCACTCAGTTTATTTTATTTGCAGAAATTTGAGCCTCTGTT
\ No newline at end of file
diff --git a/t/data/reformat_input_gffs/expected_fixed_query_3.gff b/t/data/reformat_input_gffs/expected_fixed_query_3.gff
new file mode 100644
index 0000000..1d7dca1
--- /dev/null
+++ b/t/data/reformat_input_gffs/expected_fixed_query_3.gff
@@ -0,0 +1,220 @@
+##gff-version 3
+##sequence-region abc|SC|contig000001 1 15000
+abc|SC|contig000001 Prodigal:2.60 CDS 172 1131 . - 0 ID=1_1___6;gene=different;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:Q2G1X0,protein motif:TIGRFAMs:TIGR01002,protein motif:Pfam:PF07968.6;locus_tag=abc_00001;product=Alpha-toxin,beta-channel forming cytolysin,Leukocidin/Hemolysin toxin family protein;protein_id=gnl|SC|abc_00001
+abc|SC|contig000001 Prodigal:2.60 CDS 1804 1950 . + 0 ID=abc_00002___7;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00002;product=hypothetical protein;protein_id=gnl|SC|abc_00002
+abc|SC|contig000001 Prodigal:2.60 CDS 1934 2131 . + 0 ID=abc_00003___8;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00003;product=hypothetical protein;protein_id=gnl|SC|abc_00003
+abc|SC|contig000001 Prodigal:2.60 CDS 2621 3337 . - 0 ID=abc_00004___9;inference=ab initio prediction:Prodigal:2.60,protein motif:CLUSTERS:PRK13350,protein motif:Pfam:PF02876.11;locus_tag=abc_00004;product=superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00004
+abc|SC|contig000001 Prodigal:2.60 CDS 3445 4170 . - 0 ID=1_2___10;gene=speH;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P0C0I6,protein motif:CLUSTERS:PRK13349,protein motif:Pfam:PF02876.11;locus_tag=abc_00005;note=SPE H;product=hypothetical protein,superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00005
+##FASTA
+>abc|SC|contig000001
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
+ATACCCACCACATTTGGTGGAGAACCAAAAATTAGCCGAAAAACATCATTTCTGAAGTTA
+TCGGCTAAAGTTATAAATTATATTTATTTGTACATGAACAAATAATTTACATTAATTTGT
+CATTTCTTCTTTTTCCCAATCGATTTTATATCTTTCTGAAGAACGATCTGTCCATTTATC
+TTTAGTATTGGTACCTTTCCAATTTGTTGAAGTCCAATGCAATTGGTAGTCATCACGAAC
+TCGTTCGTATATTACATCTATATTTGTTTGTTGTTTGGATGCTTTTCTATCCATAGTAAT
+AACTGTAGCGAAGTCTGGTGAAAACCCTGAAGATAATAGAGAACTTGCTTTGTTAGGATC
+AAGGAAGTTCTCTGCTGCTTTCATAGAACCATTTCTAGTTTTCATGAAAAGTTGATTGCC
+ATATACCGGGTTCCAAGAATCTCTATCATATGGTCCCCAATTTTGATTCACCATATTGTT
+AAATATCACTTTCCAGCCTACTTTTTTATCAGTTGGGCTCTCTAAAATTGTTTTGAAATC
+AGGTTGAACATATTTCAGTGTATGACCAATCGAAACATTTGCACCAATAAGGCCGCCAAT
+TTTTCCTGTATCATCACCAGTAACATTACCGTTGAATCCATAAGTTAAAGTACTCATATA
+CTCTTTTGTATCAATCGAATTTCTTGGATAGTAATCAGATATTTGAGCTACTTCATTATC
+AGGTAGTTGCAACTGTACCTTAAAGGCTGAAGGCCAGGCTAAACCACTTTTGTTAGCACC
+TTCTTCGCTATAAACTCTATATTGACCAGCAATGGTACCTTTCGTTCTAATAACTAGCAG
+TTTTTTATTGTGATTTTTATCATCGATAAAACTATAAAATACTTTTTTGTGCATGCCATT
+TTCTTTATCATAAGTGACTAAATCACCTGTTTTTACTGTAGTATTGCTTCCAATATCTGT
+AGTACCGGTTTTAATATTAATATCAGAATCTGCGGCATTAGCGACAGGATTCATTAATAT
+GGAACCTAGCAATAGTGTTGTTGTTACTGAGCTGACTATACGTGTTTTCATTTTCATCAT
+CCTTCTATTTTTTTTAACGATTTGAGGAAACAATAATCAATATGTCAATTTAGAATATTG
+CAGTTGAGACATATCAAATATTTATAATCGTTTATATTAGTATATTTAATGTAGCAACTG
+ATAAATTACTGAGTGATGATGAGTGATTATTTTAAGAATATGTTTTTAACTTTTATTTAA
+AATTTGAAAGGAAGCATTTCAATTTCGAGGGTTAGTCAAAGTTGAATAAATTCTTTATGA
+AACAAGGAAAAGACATAGCTAATTTTATTGATTAATTTCTTTAAAACTAATGATTTGTTT
+GATTTAAAAATGTAATCGATTACAATATAAAAATACAAATATCTTAGAATTAAATCAATT
+AATTAACTATTAAATAAAAATTAAATATATATTAACTACTGTAAATTAATAAATAGAAAT
+AGAGAAAAAGGGTATTAATTATGTTTGGAATTTCGTCGGGAATAATTTTTGCCATTACAT
+AGAAATATCTAATAGATAATGAAAAAGTATCGTATGTATTTTTAATATAGTGTAAAATAT
+CATATGTAAAATAAAATGTAGATTTTTAGTTAGAGGCATTATAAGAAAATTTTGAGTATA
+GGTTAGCTTTTAATTATGAATCTTATTGAAATTTGATTAATAAATATATGATAGGGGATT
+AAAATGAAACTATTTTATATCGTATTTCTTATTATTATATGGCTGAATATATTTTTAGGA
+AATGAAATTATCCATACACTGACTGTTTTAATAACAACATTGTATATTGTTAATTCAAGA
+AAGGGGATTAAAAATGACAGAGTTGAATAATATTATAAACTCTCTTCAATCTTTGTTTGA
+GTCTGAATCAGGCTATAAAATTTCGAAAAATTCAGGAGTTCCATATCAAACAGTACAAGA
+TTTAAGAAATGGGAAAACCAAACTAGAAGATGCTAGATTTAGAACGATTATTAAACTTTA
+TAGTTACTATGTCTCATTAAAAGAACATTAATCATGGGACAATAAAGTATTGCTATAATA
+ATTGAATCATTAAATGAAGGAATAGAGCCTAAGACATAATAAATCAATGTCTTAGGCTCT
+ACAATATTATATTGGTAGTAGTTGACCGAATGAAAATGACCATGTAACAAGCATTTTTGG
+GGCCCCAACACAGAAGCTGACGAAAAGTCAGCTTACAATAATGTGCAAGTTGGGGATGGG
+CCCCAACACAGAGAATTTCAAAAAGAAATTCTACAGACAATGCAAGTTGGCGGGGCCCCA
+ACATAGAGAAATTCAAAAAGAAATTCTACAGACAATGCAAGTTGGGGAGTGACAACGAAA
+TAAATTTTATAAAATACCATTTCTGTCACATTCCTACTCCCAATTCCATTTAAATATATA
+GAAAATTTCACCTATTATATACATCATACACTTTAAAAATTATCATTTAAATAATCTGAT
+TTGGAATTAAAGTGCATGAAGTATAAGTCACCTTCATATACTAATCAAAGAGGACGTCAA
+CAGTTATTTTATTAGGATTTTTAACATAAACATTTGCTAGATCTGAATGTAATCTTTTGC
+TTAAATCAATAGTGTAGTTATTACCGCCACCGGTGATCTTAAGCTTACCTTTATTACGAT
+TTTCGGTATATAATATTTTATTTTTTATTAACGCTTCTCGTGCACGGAAATCGATTTCTT
+TCAATGTTAATACTGGTTTATTGCCTTGGTATATTTTATGCGCACCAATAATCGTTTGTA
+GTTTATCTTTGTATTGCACAAAAAGATTATAAGTTTTATCAGAAGGTTTTGCGGCTGGTG
+TAACGCCACCTGTAAATGTCTCTCTATAAGACCACCATAACTGATCAGTATCTTTGTCTT
+TTAGTCCAAACACATCTACGTAACGATCTTTTAACTGATTAATATTTCCCCAACTTTCAG
+CGCCCCATAAAGATATATGTGCTGACCATGAATATCTCTTAAGTTCAACATAAATGTTTC
+CATTATCATATTGATATAGCCATTTATTTGAAAATGAAAAATGAGGCTGTGTGTAATATT
+TAATTAATTCATTGATGTTAGTTTCATCTTGACCAATGCTATAAGCTTTAGCTTCAGAGT
+AAAAACTAAATACTGGTTTTTGATTTTGAGGTAATACAGTACCTAATAGTAATAATGTTG
+TCGTTAAAATTATATTTTTCGTGATGTTCTTACTCATTAGAACATCTCCTTTCAGAGGAA
+TCATGATACGAGGAATAAGAAATTTAAATGTGAGCGAAGTCAATATAGTATTTGCGATTA
+TTTTTATTAACTCCATTATTATTGTTAGTTTGATTTTTCGAGGATAACTTCAATTTTTGC
+ATTTTGAGGTTTTTTAACATATCTATTTGCATCAGTTGATGGCAACCTTTTACTTAAATC
+TATTGTGTAGTTATTGTCTGTACCTGTTATTTTAATTTGTCCTTTATTATAAGAATTATT
+ATATAATTTTTTACTTTTAATTAATGTTTGACGAATACGAAAATCTAATTCTTTTAAAGT
+TAAAACAGGCTTATTGCCTTCATAAACTGGAAATCCGCCAGTAAACGTTTCTGCTTTATC
+TTTATATGTTACATTCAGTTTATAGTGTTTATCGTTAGATGTTGCTGCAGGAGTAACACC
+ACCAGTAAACGTTTCTTGAGATAATGCAAAAGAATCAATGGTTTCTTGGTCTTTTATGCC
+AAAAATATCAACGCTTTTATTTCTTAATTGGTTGATATTGCCCCAACTTTCAGGTCCATA
+AACTTGAATATGACTATACCAAGAAAACTGTAACAACGTTGCATGAATCGTACCGTTATC
+TTTTTGCCATAACGTACTGTTAGAGAAGGTTAAATATTTTTGCGAGTAATATTTAGTTAA
+CTCATTAACGTTAGTTTCGTTTTGATTTATATAATAAGCTTTCGCTTCAGATGAAGAATT
+GATAGGTGTATTAGGAAATTGTGTAAATGCTGTACCTAATAGTAACAATGTTGTTGATAA
+AATAATTTTTTTCGTGATGTTATTGTTCATTCGAATTTCTCCTTTGAGTATTGTTGGAAT
+GTTTAATTATAAAAAGGGGTTAATTAGATAATTGAAATTATCCGCATTTACAAAAGGTAA
+TAGGTTAGTTAGATTTTTCGAGTATGACTTCAATTTGTGCATTTTTAGGATTTTTAACAT
+AACGGTTTGTGTCAGTTAATTTTAACTTTTTACTTAAATCAATCGTGTAATTATTTCCAT
+CAGCAGTTATCTTAATTTGACCTTTATTAAATTCTCCGTTATATAACTTTTTATTCTTTA
+TTAATGTTTGACGAATACGGAAATCTAATTCTTTTAAAGTTAATACTGGTTTATTTCCTT
+TGTAAAATTCATGTCCACCGATGATAGTTTGTTGTTTATCACTATATTTTAAAAATAGTC
+TATAAGGTTTATCAGATGAAGTAGCTGCTGGCGTAACACCACCAGTAAATGTTTCATCAT
+AAGTCCAGTAACCTTCAACTGTGTCCTCATCTTTAGTTCCAAATATATCAACGTATTTAT
+TTCTTAACTGATTAATGTTTCCCCAACTCTCGGATCCAAACACTTGAATATGACTATACC
+AAACCCACGTTTGCAATGTTGCATGAATGCTACCATTGGGCTTTTGCCATAGCCATTTTC
+CAGATAATGAAAAATGCGGCTGAGTGTAATATTTGATTAACTCATTGATATTAGTCTCGT
+TTTCACTGATATTATAGGCTTTTGCTTCAGATGAAAAACTGATTGGTGTTTTAGGAAGTT
+GTGTTGATGTGGTTCCTAAAAGTAACAATGCTGTTGATAAAACTAATTTATTCATGATGT
+TCTTTTTCATATGAAAATCTCCTTTGCGTGAATTACCCAAAGTATATAAGCTATTACACC
+GATTCGGAATTAAATAAAAGCTAAAACTATGTTAAATAAACTTAAACAGTTAGTAGTGTT
+ATTTAAGCAAAACTTATCATTTTTAAGTTTTGGACAGAAACAGTACTTAATAAAGTAGGC
+GGGAGTTATATATTAAAAACGACACGTTACAATTATTCTCTAATCAATTGCATTAAATTG
+TTTGATAATTGAATTTTCTAACTACTTGAAAAATAGTTATACTTTAAATGTAGTACTTAT
+TTTAATTATTTCCTACTACTTAAATTTAATATTAATAAAATGTTCATTTAATTATTGATA
+AAATATTACAAATTTTAATAGTAGGTTGTGTTTATTTTGTATGCGCTTACAATTTAGGTG
+TAACTAAAATAAAAGGAGTTGTTATTAATGAAAAATTTACGAAACAGAAGTTTTTTAACT
+TTATTAGACTTTTCACGACAAGAGGTAGAATTCTTATTAACACTCTCCGAGGATTTAAAA
+CGTGCTAAATATATTGGCACTGAAAAGCCTATGTTAAAAAATAAAAATATTGCACTGTTA
+TTTGAAAAAGATTCTACAAGAACGCGATGTGCATTTGAAGTTGCAGCGCATGATCAAGGT
+GCAAATGTAACTTATTTAGGCCCAACTGGATCACAAATGGGTAAAAAAGAAACAACTAAA
+GATACTGCACGTGTGCTTGGTGGAATGTATGATGGCATTGAATACCGTGGTTTTTCACAA
+AGAACAGTAGAAACTTTAGCTGAAAATTCAGGCGTACCAGTGTGGAATGGTTTAACTGAT
+GAAGATCATCCTACTCAAGTTCTTGCTGATTTCTTAACAGCAAAAGAAGTCTTAAAAAAA
+GATTATGCAGATATTAACTTTACATATGTTGGAGATGGTCGTAATAACGTTGCAAATGCA
+TTAATGCAAGGTGCTGCCATTATGGGTATGAACTTCCATTTAGTTTGTCCAAAAGAATTA
+AATCCAACAGATGAATTATTAAATCGCTGTAAAAATATTGCCGCTGAAAATGGTGGCAAC
+ATATTAATCACAGATGATATTGACCAAGGTGTAAAAGGTTCGGATGTAATTTACACTGAT
+GTTTGGGTATCAATGGGTGAACCTGATGAAGTATGGAAAGAACGACTTGAATTATTGAAA
+CCATATCAAGTAAATAAAGAAATGATGGATAAAACTGGTAATCCAAATGTTATTTTTGAG
+CATTGCTTACCATCTTTCCATAATGCTGATACGAAAATTGGTCAACAAATTTTTGAAAAA
+TATGGTATTCGAGAAATGGAAGTTACAGATGAAGTATTCGAAAGTAAAGCTTCAGTTGTA
+TTCCAAGAAGCTGAGAACAGAATGCATACAATCAAAGCAGTCATGGTTGCTACATTGGGT
+GAATTTTAAATGATATAAGGAAGTGAATATGATGGCGAAAATAGTAGTAGCATTAGGTGG
+TAATGCTTTAGGAAAATCACCTCAAGAACAACTCGAGCTTGTTAAAAATACTGCGAAATC
+ATTAGTAGGATTAATAACAAAAGGACATGAGATTGTTATTAGTCATGGTAATGGACCACA
+GGTTGGAAGCATTAATTTGGGACTTAACTATGCTGCAGAACATAACCAAGGTCCGGCATT
+TCCATTTGCTGAATGTGGCGCAATGAGTCAAGCTTACATCGGCTATCAATTACAAGAAAG
+CTTACAAAATGAATTGCATTCTATTGGAATGGATAAACAAGTGGTAACACTAGTGACACA
+AGTTGAAGTTGATGAAAATGATCCGGCATTTAACAATCCTTCAAAACCAATTGGGTTATT
+TTACAACAAAGAAGAAGCTGAACAAATTCAAAAAGAAAAAGGATTTATATTTGTTGAAGA
+TGCTGGAAGAGGATATAGACGCGTTGTTCCTTCACCACAACCCATCTCTATTATTGAATT
+AGAGAGTATTAAAACACTTATTAAAAATGATACACTCGTTATTGCTGCTGGTGGTGGAGG
+TATACCAGTAATTAGAGAGCAACATGATGGTTTTAAAGGTATTGATGCAGTTATAGACAA
+AGATAAAACAAGTGCGTTGTTGGGTGCTAATATTCAATGCGATCAATTGATTATTTTAAC
+AGCAATTGATTATGTATATATTAATTTTAACACTGAAAACCAACAGCCTTTGAAAACAAC
+AAATGTTGATGAATTAAAACGATATATAGACGAAAATCAATTTGCAAAAGGAAGTATGTT
+ACCAAAAATTGAAGCAGCCATATCATTTATTGAAAACAATCCAAAAGGAAGTGTGCTTAT
+AACATCATTAAATGAATTAGATGCTGCCTTAGAGGGTAAAGTAGGTACTGTGATTAAAAA
+GTAATTGAATTGAAACGCTTTTCAATTACTATATGTCAAATGCATGATTTTTATTATTTA
+TGTGCACCCCCTGAAAATAATGCCTCTATTTTGATGCGGGGTGCACTTTCTTAATTTATA
+TTTATAAAATCTTTAAGGTAGAAATGCTAGGTTAAATGTCGAAGGAGATGAAACCGTGGA
+AAATACAATTAATGAAAGTGAAAAGAAAAAACGATTTAAATTAAAAATGCCAGGTGCATT
+TATGATTTTATTCATTTTAACGGTTGTTGCAGTTATAGCAACATGGGTTATTCCTGCTGG
+TGCATATTCTAAACTTTCTTACGAACCTTCATCCCAAGAACTAAAGATAGTTAACCCTCA
+TAACCAAGTGAAAAAGGTTCCGGGTACGCAACAGGAACTAGACAAAATGGGGGTTAAAAT
+TAAGATTGAACAATTTAAATCAGGTGCAATTAATAAGCCAGTATCAATTCCGAATACTTA
+TGAAAGATTAAAGCAACATCCAGCTGGACCAGAACAAATAACAAGTAGCATGGTTGAAGG
+TACGATAGAAGCGGTCGATATCATGGTATTCATTCTTGTACTAGGGGGACTTATTGGCGT
+AGTTCAAGCCAGTGGTTCTTTTGAATCGGGATTGTTAGCTTTAACGAAGAAAACAAAAGG
+GCATGAATTTATGCTAATTGTGTTTGTATCAATACTAATGATTATCGGCGGGACGTTATG
+TGGTATTGAAGAAGAAGCTGTAGCATTCTATCCGATTTTAGTCCCTATATTTATAGCGTT
+AGGATACGATTCTATCGTTTCAGTTGGTGCCATATTCCTTGCCAGCTCTGTCGGTAGTAC
+ATTTTCAACTATTAACCCGTTCTCGGTTGTAATTGCCTCTAATGCCGCTGGTACAACTTT
+TACGGATGGCTTGTATTGGAGAATAGGTGCTTGTATTGTCGGTGCGATTTTTGTTATTAG
+TTATTTATATTGGTACTGTAAAAAAATTAAAAACGATCCTAAAGCGTCATATTCTTATGA
+AGACAAAGATGCTTTTGAACAGCAATGGTCTGTATTAAAAGATGACGATAGTGCCCATTT
+TACTTTGCGTAAGAAGATAATCCTTACATTATTTGTACTACCATTTCCAATTATGGTATG
+GGGAGTTATGACGCAAGGTTGGTGGTTCCCAGTTATGGCTTCAGCATTTTTAATATTTAC
+AATTATAATAATGTTTATTGCTGGGACAGGTAAATCTGGATTGGGAGAAAAAGGAACTGT
+AGATGCATTTGTCAATGGTGCATCAAGTTTAGTAGGTGTATCTTTAATTATTGGTTTAGC
+TCGAGGTATTAATTTAGTGTTGAATGAAGGTATGATTTCAGATACAATCTTACACTTTTC
+ATCATCTTTAGTTCAACATATGAGTGGACCATTATTTATCATCGTATTACTATTTATTTT
+CTTCTGTTTAGGTTTTATCGTGCCATCATCTTCTGGATTAGCGGTATTATCAATGCCTAT
+CTTTGCACCACTAGCTGATACAGTAGGTATACCAAGATTCGTCATCGTTACGACATATCA
+ATTTGGTCAATATGCGATGTTATTCTTAGCGCCGACTGGACTTGTTATGGCCACACTACA
+AATGTTAAACATGCGATATTCACATTGGTTCCGATTTGTATGGCCGGTAGTTGCTTTTGT
+ATTGATTTTCGGTGGCGGAGTACTAATTACGCAAGTACTAATTTATTCATAATTTGAAAT
+GCTATATTATAAAAATACTAATTGGGTTTTATGCATCTCGTAGGTTTGTAGAAATACTAA
+ACTAAGCGAGGTGCATTATTATTTTTGATTAAGAAAATAATGACGGTAATGATAACACTA
+GTAAGTAATTGATACAATGCTCTATTTAATAATGATATTTTTAAAATTTGTTTTTAATGT
+AATGTTAGATCTATGGTATATTATATTTATCGTGGTAAATATGTATTTGCTGTAAACAGT
+TTTTGTAACACATGACACATATGGTTGTGAAAATAGCATATATAAAGGATGGCTATAAAT
+GACACATTTGACAAAGGTTTTAGATACACTAACTGGAATATGCGTAGTATTATTATTTAG
+TAAATATTTTGTGGCGTATGCAAATATGGTGTTTGATTGGAATTTAAGATGGTATTTGCT
+AGAAAACATACCACATTTGCCAATTATATTATTTATTCTGATGTTTATTTTCGGAGTACC
+TTCTGAAATGATAAAAGATAGGCAAAGGAAAAATAACGGTGTTTAATTTATCGATATTTA
+GAGGTGATAAAATTTGTCAACTATTACAAAGACTAAAATAAAAATCTTTATTAATTATTT
+TATTGGTATATTAGCCTTGGCGTTTGCTGCTTATATATTATTTAAATAAAGGTTAGAGTG
+AAACGTGTTTATGAACTAGACGTTCTAGTATAGTTACTACAGCTTTAGTCAGAAGGTATC
+ATTGATAAGATCATATTAAATCAAAGAGGCATTGATATACACTAAAAAGAGGCAAGATTA
+CCTGCCTCTTTTTTAGTTATTAAATATGCGTGTTAATTCTTGGTAATAGTGTTACTGAGA
+CGCATTACGAAGAAATTTATCTTGATTTTCCTTTTTTAAAAAGAAGTGAAGATATCCTAT
+AAAGACTCTAAGTACTATTACAGTGGCTAATAACACTTCGATAAACAAAAGACCTTTCCA
+AATATCTGGAAACATAAGTACAGGCAAACTGTTCTTTAAAGCAGTTGCTGAGATTACTAA
+AGGGAATGTGAAAGCTGAAAATACGGGCGAAAAAGGTTCTTTTAGTAATTTAGGCAATTG
+TATAATGATATAAAAATAAAATATTTGAGCTAATATTAAAAATATAATTACGATAAAAGC
+ATTCGCCTTAGGAAAGGCTATAACATATGCTGCAGCGACTAAAGAAAATGGTGCACAAAT
+TGTCGATGTGTTCGGTTTGATTGACGTCTGCAATGGAAATGCTTTTAATCGCTTGAAAAC
+AATAGGTAAGACAATACAAGTAGCTACAAAGCCATATATTACTGTTAATTGACCTATGAA
+AAAACATCCGCTAACGGGTGCCGTCAATCCTGCGATAGCAATACCAATAAAAAGTACAGT
+CCACGAAGGATAAACATTTTCAAGTGAAAAATCTTTTAAATATTTTATTGAAAAAATAAT
+CATATGCGTCATAATTCCCACAAGGCATAAAATCCAAATAGGCGTTATTAAGCTATTGAT
+AAAAGTTATGTTACTAAAAAATGTATTTAAATAAGTAGTACCTAAAAAGCCAGACATGAA
+AAATGTTGTGAACACTGATGAAACTAGAGGACTGTTTAATTGTTCTTTCACATTATTAAA
+ATATTTGATCATAGTACATAAAAGGTGAATCCAAATCAAGAAAGCAAAGATTCCGCAAAC
+AGCGTTTAAAGTAAGAGATAAGTCTTTTAATAGATTACCCAGGCCTAATAATCCTAAGAC
+TAGTCCTGACGTTACTAGAGGTGCTTTTTGAAGTCTCATGATTTACAACCTTTCTTATGT
+GATTTTCTTCACTAATTATATCATGATAGCTATGGCCAATTAATAAGAAGAGTGTGTACT
+ATTACGTTATTAGAGTATGTATATTGGATTGATAGACACATAATTGACATTTAAATCTCA
+AAATTAATGATATTTGAGGTATGCTTTGCAACCTAAATATTGGAATATGTGGAAAAGTAA
+TTATTTAATTTAAATGATGATTGAAGATTTACAAGGGGGTGTACAAAATGAGAAATCAAA
+TTCAAAAACTATTAGACAGTGATTTGAGCAGTTTACATATATCGAAACAAACAGGAGTTC
+CACAAAGCACAATACACAGAATGAGAAAAAAAGAAAGATCATTAGACAATATGTCATTGA
+AAAACGCTGAACTACTTTATAAATTTGCCAATAGTATATTTAGCAATGAAAATTAAGAAG
+AATAATTAGTGAGTTAAATAATTAAAAAACCACGTCTCGATGGACGTGGTTATTTTTTTA
+AATGTATTTAATTATAGGATTTCGGGCCCCTGAAAAGTCCCTAAAATTTTGAATAGTATC
+AAAATCTATAGGAATAATATAATAATAAAAATCTCTACGCATGCAAATGGTGAGTGTTAA
+AAATCTTGGTGTAGTGTTGGTGTAGTTCAGGTGCAGTATAGATGAAATTTGAGCACAAAA
+TTACTTAATTAAAAATGTATAAACAAGTGTCAGACGCGTGTCAATTGTGTGTCAAAAAAT
+TCTATGACGAATAAGCATGCTTGTTTTAATTACTGTATTTTCGGGGCTTATGCGGGGGAC
+GTTTTGGTGACGCATCATACTATATTACTGAAATTCAAAACAAAAAGAGCCCCGTAATCA
+CGGAACTCTTTTGTTTGGTAATGCGTATAAAAATACCTATAAACGTCCTGGGAGGGATTC
+GAACCCCCGACCGATGGCTTAGAAGGCCATTGCTCTATCCAGCTGAGCTACCAGGACACG
+TTTAACAACACAAGAATTATTATATCTAAATGAACTTAAATTAGCAATACCTTGTAAATA
+AAAAATGTTTATATTTTTCACTATTATAGAGCTATTTATCTAAAAAGGTTCAATAAGACT
+TAAATGCGAATTCAGGCAACTTAATTGTGTTAAATACAGTTTTGAATGCCTAACTGTATT
+TCTTTTCTCTTTAAAATACAGTTAAGTACATTATAAGATGTTGTGCGGATAAACAAACTA
+ATTGCATCAAATTTATTTTAAAATAACAACAACAAAACGTTAAGCGAATAACATTTCGGT
+GATTTAAAAGCTACGCACGTTTTTGTTATCTTCAAATTTAAATTTTAAGGAGTGTTTTCA
+ATGGAAGGTTTATTTAACGCAATTAAAGATACCGTAACTGCAGCAATTAATAATGATGGC
+GCAAAATTAGGCACAAGCATTGTGAGCATCGTTGAAAATGGCGTAGGTTTATTAGGTAAA
+TTATTCGGATTCTAATTTCAATATGTTATGTAAGTAATCAGTATTATTTCAAAGGTGAGG
+GAGAGATTTAAATGACTGGACTAGCAGAAGCAATCGCAAATACTGTGCAAGCTGCACAAC
+AACATGATAGTGTGAAATTAGGCACAAGTATCGTAGACATCGTTGCTAACGGTGTGGGTT
+TACTAGGTAAATTATTTGGATTCTAATATAATAACTAATATTCTTTAAAATAAACTGGGT
+GAGCATACTTTAATGTTATGCACTCAGTTTATTTTATTTGCAGAAATTTGAGCCTCTGTT
\ No newline at end of file
diff --git a/t/data/reformat_input_gffs/expected_real_1.gff b/t/data/reformat_input_gffs/expected_real_1.gff
new file mode 100644
index 0000000..36af703
--- /dev/null
+++ b/t/data/reformat_input_gffs/expected_real_1.gff
@@ -0,0 +1,223 @@
+##gff-version 3
+##sequence-region 2 1 15000
+2 annotation remark 1 15000 . . . ID=id___1;accessions=REL607;comment=Source DNAEscherichia
+2 feature source 1 4629812 . + . ID=id___2;mol_type=genomic DNA;organism=Escherichia coli;strain=REL607
+2 feature CDS 190 255 . + 0 ID=id___3;codon_start=1;gene=thrL;locus_tag=ABC_00001;note=b0001;product=thr operon leader peptide;protein_id=kribb:ABC_00001;transl_table=11;translation=MKRISTTITTTITITTGNGAG
+2 feature gene 190 255 . + . ID=id___4;gene=thrL;locus_tag=ABC_00001
+2 feature CDS 336 2798 . + 0 ID=id___5;EC_number=2.7.2.4,1.1.1.3;codon_start=1;gene=thrA;locus_tag=ABC_00002;note=b0002;product=bifunctional aspartokinase I/homeserine dehydrogenase I;protein_id=kribb:ABC_00002;transl_table=11;translation=MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTISGQDALPNISDAERIFAELLTGLAAAQPGFPLAQLKTFVDQEFAQIKHVLHGISLLGQCPDSINAALICRGEKMSIAIMAGVLEARGHNVTVIDPVEKLLAVGHYLESTVDIAESTRRIAASRIPADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQVPDARLLKSMSYQE [...]
+2 feature gene 336 2798 . + . ID=id___6;gene=thrA
+2 feature CDS 2800 3732 . + 0 ID=id___7;EC_number=2.7.1.39;codon_start=1;gene=thrB;locus_tag=ABC_00003;note=b0003;product=homoserine kinase;protein_id=kribb:ABC_00003;transl_table=11;translation=MVKVYAPASSANMSVGFDVLGAAVTPVDGALLGDVVTVEAAETFSLNNLGRFADKLPSEPRENIVYQCWERFCQELGKQIPVAMTLEKNMPIGSGLGSSACSVVAALMAMNEHCGKPLNDTRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENDIISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQPELAAKLMKDVIAEPYRERLLPGFRQARQAVAEIGAVASGISGSGPTLFALCDKPDTAQRVADWLGKNYLQNQEGFVHI [...]
+2 feature gene 2800 3732 . + . ID=id___8;gene=thrB;locus_tag=ABC_00003
+##FASTA
+>2
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
+ATACCCACCACATTTGGTGGAGAACCAAAAATTAGCCGAAAAACATCATTTCTGAAGTTA
+TCGGCTAAAGTTATAAATTATATTTATTTGTACATGAACAAATAATTTACATTAATTTGT
+CATTTCTTCTTTTTCCCAATCGATTTTATATCTTTCTGAAGAACGATCTGTCCATTTATC
+TTTAGTATTGGTACCTTTCCAATTTGTTGAAGTCCAATGCAATTGGTAGTCATCACGAAC
+TCGTTCGTATATTACATCTATATTTGTTTGTTGTTTGGATGCTTTTCTATCCATAGTAAT
+AACTGTAGCGAAGTCTGGTGAAAACCCTGAAGATAATAGAGAACTTGCTTTGTTAGGATC
+AAGGAAGTTCTCTGCTGCTTTCATAGAACCATTTCTAGTTTTCATGAAAAGTTGATTGCC
+ATATACCGGGTTCCAAGAATCTCTATCATATGGTCCCCAATTTTGATTCACCATATTGTT
+AAATATCACTTTCCAGCCTACTTTTTTATCAGTTGGGCTCTCTAAAATTGTTTTGAAATC
+AGGTTGAACATATTTCAGTGTATGACCAATCGAAACATTTGCACCAATAAGGCCGCCAAT
+TTTTCCTGTATCATCACCAGTAACATTACCGTTGAATCCATAAGTTAAAGTACTCATATA
+CTCTTTTGTATCAATCGAATTTCTTGGATAGTAATCAGATATTTGAGCTACTTCATTATC
+AGGTAGTTGCAACTGTACCTTAAAGGCTGAAGGCCAGGCTAAACCACTTTTGTTAGCACC
+TTCTTCGCTATAAACTCTATATTGACCAGCAATGGTACCTTTCGTTCTAATAACTAGCAG
+TTTTTTATTGTGATTTTTATCATCGATAAAACTATAAAATACTTTTTTGTGCATGCCATT
+TTCTTTATCATAAGTGACTAAATCACCTGTTTTTACTGTAGTATTGCTTCCAATATCTGT
+AGTACCGGTTTTAATATTAATATCAGAATCTGCGGCATTAGCGACAGGATTCATTAATAT
+GGAACCTAGCAATAGTGTTGTTGTTACTGAGCTGACTATACGTGTTTTCATTTTCATCAT
+CCTTCTATTTTTTTTAACGATTTGAGGAAACAATAATCAATATGTCAATTTAGAATATTG
+CAGTTGAGACATATCAAATATTTATAATCGTTTATATTAGTATATTTAATGTAGCAACTG
+ATAAATTACTGAGTGATGATGAGTGATTATTTTAAGAATATGTTTTTAACTTTTATTTAA
+AATTTGAAAGGAAGCATTTCAATTTCGAGGGTTAGTCAAAGTTGAATAAATTCTTTATGA
+AACAAGGAAAAGACATAGCTAATTTTATTGATTAATTTCTTTAAAACTAATGATTTGTTT
+GATTTAAAAATGTAATCGATTACAATATAAAAATACAAATATCTTAGAATTAAATCAATT
+AATTAACTATTAAATAAAAATTAAATATATATTAACTACTGTAAATTAATAAATAGAAAT
+AGAGAAAAAGGGTATTAATTATGTTTGGAATTTCGTCGGGAATAATTTTTGCCATTACAT
+AGAAATATCTAATAGATAATGAAAAAGTATCGTATGTATTTTTAATATAGTGTAAAATAT
+CATATGTAAAATAAAATGTAGATTTTTAGTTAGAGGCATTATAAGAAAATTTTGAGTATA
+GGTTAGCTTTTAATTATGAATCTTATTGAAATTTGATTAATAAATATATGATAGGGGATT
+AAAATGAAACTATTTTATATCGTATTTCTTATTATTATATGGCTGAATATATTTTTAGGA
+AATGAAATTATCCATACACTGACTGTTTTAATAACAACATTGTATATTGTTAATTCAAGA
+AAGGGGATTAAAAATGACAGAGTTGAATAATATTATAAACTCTCTTCAATCTTTGTTTGA
+GTCTGAATCAGGCTATAAAATTTCGAAAAATTCAGGAGTTCCATATCAAACAGTACAAGA
+TTTAAGAAATGGGAAAACCAAACTAGAAGATGCTAGATTTAGAACGATTATTAAACTTTA
+TAGTTACTATGTCTCATTAAAAGAACATTAATCATGGGACAATAAAGTATTGCTATAATA
+ATTGAATCATTAAATGAAGGAATAGAGCCTAAGACATAATAAATCAATGTCTTAGGCTCT
+ACAATATTATATTGGTAGTAGTTGACCGAATGAAAATGACCATGTAACAAGCATTTTTGG
+GGCCCCAACACAGAAGCTGACGAAAAGTCAGCTTACAATAATGTGCAAGTTGGGGATGGG
+CCCCAACACAGAGAATTTCAAAAAGAAATTCTACAGACAATGCAAGTTGGCGGGGCCCCA
+ACATAGAGAAATTCAAAAAGAAATTCTACAGACAATGCAAGTTGGGGAGTGACAACGAAA
+TAAATTTTATAAAATACCATTTCTGTCACATTCCTACTCCCAATTCCATTTAAATATATA
+GAAAATTTCACCTATTATATACATCATACACTTTAAAAATTATCATTTAAATAATCTGAT
+TTGGAATTAAAGTGCATGAAGTATAAGTCACCTTCATATACTAATCAAAGAGGACGTCAA
+CAGTTATTTTATTAGGATTTTTAACATAAACATTTGCTAGATCTGAATGTAATCTTTTGC
+TTAAATCAATAGTGTAGTTATTACCGCCACCGGTGATCTTAAGCTTACCTTTATTACGAT
+TTTCGGTATATAATATTTTATTTTTTATTAACGCTTCTCGTGCACGGAAATCGATTTCTT
+TCAATGTTAATACTGGTTTATTGCCTTGGTATATTTTATGCGCACCAATAATCGTTTGTA
+GTTTATCTTTGTATTGCACAAAAAGATTATAAGTTTTATCAGAAGGTTTTGCGGCTGGTG
+TAACGCCACCTGTAAATGTCTCTCTATAAGACCACCATAACTGATCAGTATCTTTGTCTT
+TTAGTCCAAACACATCTACGTAACGATCTTTTAACTGATTAATATTTCCCCAACTTTCAG
+CGCCCCATAAAGATATATGTGCTGACCATGAATATCTCTTAAGTTCAACATAAATGTTTC
+CATTATCATATTGATATAGCCATTTATTTGAAAATGAAAAATGAGGCTGTGTGTAATATT
+TAATTAATTCATTGATGTTAGTTTCATCTTGACCAATGCTATAAGCTTTAGCTTCAGAGT
+AAAAACTAAATACTGGTTTTTGATTTTGAGGTAATACAGTACCTAATAGTAATAATGTTG
+TCGTTAAAATTATATTTTTCGTGATGTTCTTACTCATTAGAACATCTCCTTTCAGAGGAA
+TCATGATACGAGGAATAAGAAATTTAAATGTGAGCGAAGTCAATATAGTATTTGCGATTA
+TTTTTATTAACTCCATTATTATTGTTAGTTTGATTTTTCGAGGATAACTTCAATTTTTGC
+ATTTTGAGGTTTTTTAACATATCTATTTGCATCAGTTGATGGCAACCTTTTACTTAAATC
+TATTGTGTAGTTATTGTCTGTACCTGTTATTTTAATTTGTCCTTTATTATAAGAATTATT
+ATATAATTTTTTACTTTTAATTAATGTTTGACGAATACGAAAATCTAATTCTTTTAAAGT
+TAAAACAGGCTTATTGCCTTCATAAACTGGAAATCCGCCAGTAAACGTTTCTGCTTTATC
+TTTATATGTTACATTCAGTTTATAGTGTTTATCGTTAGATGTTGCTGCAGGAGTAACACC
+ACCAGTAAACGTTTCTTGAGATAATGCAAAAGAATCAATGGTTTCTTGGTCTTTTATGCC
+AAAAATATCAACGCTTTTATTTCTTAATTGGTTGATATTGCCCCAACTTTCAGGTCCATA
+AACTTGAATATGACTATACCAAGAAAACTGTAACAACGTTGCATGAATCGTACCGTTATC
+TTTTTGCCATAACGTACTGTTAGAGAAGGTTAAATATTTTTGCGAGTAATATTTAGTTAA
+CTCATTAACGTTAGTTTCGTTTTGATTTATATAATAAGCTTTCGCTTCAGATGAAGAATT
+GATAGGTGTATTAGGAAATTGTGTAAATGCTGTACCTAATAGTAACAATGTTGTTGATAA
+AATAATTTTTTTCGTGATGTTATTGTTCATTCGAATTTCTCCTTTGAGTATTGTTGGAAT
+GTTTAATTATAAAAAGGGGTTAATTAGATAATTGAAATTATCCGCATTTACAAAAGGTAA
+TAGGTTAGTTAGATTTTTCGAGTATGACTTCAATTTGTGCATTTTTAGGATTTTTAACAT
+AACGGTTTGTGTCAGTTAATTTTAACTTTTTACTTAAATCAATCGTGTAATTATTTCCAT
+CAGCAGTTATCTTAATTTGACCTTTATTAAATTCTCCGTTATATAACTTTTTATTCTTTA
+TTAATGTTTGACGAATACGGAAATCTAATTCTTTTAAAGTTAATACTGGTTTATTTCCTT
+TGTAAAATTCATGTCCACCGATGATAGTTTGTTGTTTATCACTATATTTTAAAAATAGTC
+TATAAGGTTTATCAGATGAAGTAGCTGCTGGCGTAACACCACCAGTAAATGTTTCATCAT
+AAGTCCAGTAACCTTCAACTGTGTCCTCATCTTTAGTTCCAAATATATCAACGTATTTAT
+TTCTTAACTGATTAATGTTTCCCCAACTCTCGGATCCAAACACTTGAATATGACTATACC
+AAACCCACGTTTGCAATGTTGCATGAATGCTACCATTGGGCTTTTGCCATAGCCATTTTC
+CAGATAATGAAAAATGCGGCTGAGTGTAATATTTGATTAACTCATTGATATTAGTCTCGT
+TTTCACTGATATTATAGGCTTTTGCTTCAGATGAAAAACTGATTGGTGTTTTAGGAAGTT
+GTGTTGATGTGGTTCCTAAAAGTAACAATGCTGTTGATAAAACTAATTTATTCATGATGT
+TCTTTTTCATATGAAAATCTCCTTTGCGTGAATTACCCAAAGTATATAAGCTATTACACC
+GATTCGGAATTAAATAAAAGCTAAAACTATGTTAAATAAACTTAAACAGTTAGTAGTGTT
+ATTTAAGCAAAACTTATCATTTTTAAGTTTTGGACAGAAACAGTACTTAATAAAGTAGGC
+GGGAGTTATATATTAAAAACGACACGTTACAATTATTCTCTAATCAATTGCATTAAATTG
+TTTGATAATTGAATTTTCTAACTACTTGAAAAATAGTTATACTTTAAATGTAGTACTTAT
+TTTAATTATTTCCTACTACTTAAATTTAATATTAATAAAATGTTCATTTAATTATTGATA
+AAATATTACAAATTTTAATAGTAGGTTGTGTTTATTTTGTATGCGCTTACAATTTAGGTG
+TAACTAAAATAAAAGGAGTTGTTATTAATGAAAAATTTACGAAACAGAAGTTTTTTAACT
+TTATTAGACTTTTCACGACAAGAGGTAGAATTCTTATTAACACTCTCCGAGGATTTAAAA
+CGTGCTAAATATATTGGCACTGAAAAGCCTATGTTAAAAAATAAAAATATTGCACTGTTA
+TTTGAAAAAGATTCTACAAGAACGCGATGTGCATTTGAAGTTGCAGCGCATGATCAAGGT
+GCAAATGTAACTTATTTAGGCCCAACTGGATCACAAATGGGTAAAAAAGAAACAACTAAA
+GATACTGCACGTGTGCTTGGTGGAATGTATGATGGCATTGAATACCGTGGTTTTTCACAA
+AGAACAGTAGAAACTTTAGCTGAAAATTCAGGCGTACCAGTGTGGAATGGTTTAACTGAT
+GAAGATCATCCTACTCAAGTTCTTGCTGATTTCTTAACAGCAAAAGAAGTCTTAAAAAAA
+GATTATGCAGATATTAACTTTACATATGTTGGAGATGGTCGTAATAACGTTGCAAATGCA
+TTAATGCAAGGTGCTGCCATTATGGGTATGAACTTCCATTTAGTTTGTCCAAAAGAATTA
+AATCCAACAGATGAATTATTAAATCGCTGTAAAAATATTGCCGCTGAAAATGGTGGCAAC
+ATATTAATCACAGATGATATTGACCAAGGTGTAAAAGGTTCGGATGTAATTTACACTGAT
+GTTTGGGTATCAATGGGTGAACCTGATGAAGTATGGAAAGAACGACTTGAATTATTGAAA
+CCATATCAAGTAAATAAAGAAATGATGGATAAAACTGGTAATCCAAATGTTATTTTTGAG
+CATTGCTTACCATCTTTCCATAATGCTGATACGAAAATTGGTCAACAAATTTTTGAAAAA
+TATGGTATTCGAGAAATGGAAGTTACAGATGAAGTATTCGAAAGTAAAGCTTCAGTTGTA
+TTCCAAGAAGCTGAGAACAGAATGCATACAATCAAAGCAGTCATGGTTGCTACATTGGGT
+GAATTTTAAATGATATAAGGAAGTGAATATGATGGCGAAAATAGTAGTAGCATTAGGTGG
+TAATGCTTTAGGAAAATCACCTCAAGAACAACTCGAGCTTGTTAAAAATACTGCGAAATC
+ATTAGTAGGATTAATAACAAAAGGACATGAGATTGTTATTAGTCATGGTAATGGACCACA
+GGTTGGAAGCATTAATTTGGGACTTAACTATGCTGCAGAACATAACCAAGGTCCGGCATT
+TCCATTTGCTGAATGTGGCGCAATGAGTCAAGCTTACATCGGCTATCAATTACAAGAAAG
+CTTACAAAATGAATTGCATTCTATTGGAATGGATAAACAAGTGGTAACACTAGTGACACA
+AGTTGAAGTTGATGAAAATGATCCGGCATTTAACAATCCTTCAAAACCAATTGGGTTATT
+TTACAACAAAGAAGAAGCTGAACAAATTCAAAAAGAAAAAGGATTTATATTTGTTGAAGA
+TGCTGGAAGAGGATATAGACGCGTTGTTCCTTCACCACAACCCATCTCTATTATTGAATT
+AGAGAGTATTAAAACACTTATTAAAAATGATACACTCGTTATTGCTGCTGGTGGTGGAGG
+TATACCAGTAATTAGAGAGCAACATGATGGTTTTAAAGGTATTGATGCAGTTATAGACAA
+AGATAAAACAAGTGCGTTGTTGGGTGCTAATATTCAATGCGATCAATTGATTATTTTAAC
+AGCAATTGATTATGTATATATTAATTTTAACACTGAAAACCAACAGCCTTTGAAAACAAC
+AAATGTTGATGAATTAAAACGATATATAGACGAAAATCAATTTGCAAAAGGAAGTATGTT
+ACCAAAAATTGAAGCAGCCATATCATTTATTGAAAACAATCCAAAAGGAAGTGTGCTTAT
+AACATCATTAAATGAATTAGATGCTGCCTTAGAGGGTAAAGTAGGTACTGTGATTAAAAA
+GTAATTGAATTGAAACGCTTTTCAATTACTATATGTCAAATGCATGATTTTTATTATTTA
+TGTGCACCCCCTGAAAATAATGCCTCTATTTTGATGCGGGGTGCACTTTCTTAATTTATA
+TTTATAAAATCTTTAAGGTAGAAATGCTAGGTTAAATGTCGAAGGAGATGAAACCGTGGA
+AAATACAATTAATGAAAGTGAAAAGAAAAAACGATTTAAATTAAAAATGCCAGGTGCATT
+TATGATTTTATTCATTTTAACGGTTGTTGCAGTTATAGCAACATGGGTTATTCCTGCTGG
+TGCATATTCTAAACTTTCTTACGAACCTTCATCCCAAGAACTAAAGATAGTTAACCCTCA
+TAACCAAGTGAAAAAGGTTCCGGGTACGCAACAGGAACTAGACAAAATGGGGGTTAAAAT
+TAAGATTGAACAATTTAAATCAGGTGCAATTAATAAGCCAGTATCAATTCCGAATACTTA
+TGAAAGATTAAAGCAACATCCAGCTGGACCAGAACAAATAACAAGTAGCATGGTTGAAGG
+TACGATAGAAGCGGTCGATATCATGGTATTCATTCTTGTACTAGGGGGACTTATTGGCGT
+AGTTCAAGCCAGTGGTTCTTTTGAATCGGGATTGTTAGCTTTAACGAAGAAAACAAAAGG
+GCATGAATTTATGCTAATTGTGTTTGTATCAATACTAATGATTATCGGCGGGACGTTATG
+TGGTATTGAAGAAGAAGCTGTAGCATTCTATCCGATTTTAGTCCCTATATTTATAGCGTT
+AGGATACGATTCTATCGTTTCAGTTGGTGCCATATTCCTTGCCAGCTCTGTCGGTAGTAC
+ATTTTCAACTATTAACCCGTTCTCGGTTGTAATTGCCTCTAATGCCGCTGGTACAACTTT
+TACGGATGGCTTGTATTGGAGAATAGGTGCTTGTATTGTCGGTGCGATTTTTGTTATTAG
+TTATTTATATTGGTACTGTAAAAAAATTAAAAACGATCCTAAAGCGTCATATTCTTATGA
+AGACAAAGATGCTTTTGAACAGCAATGGTCTGTATTAAAAGATGACGATAGTGCCCATTT
+TACTTTGCGTAAGAAGATAATCCTTACATTATTTGTACTACCATTTCCAATTATGGTATG
+GGGAGTTATGACGCAAGGTTGGTGGTTCCCAGTTATGGCTTCAGCATTTTTAATATTTAC
+AATTATAATAATGTTTATTGCTGGGACAGGTAAATCTGGATTGGGAGAAAAAGGAACTGT
+AGATGCATTTGTCAATGGTGCATCAAGTTTAGTAGGTGTATCTTTAATTATTGGTTTAGC
+TCGAGGTATTAATTTAGTGTTGAATGAAGGTATGATTTCAGATACAATCTTACACTTTTC
+ATCATCTTTAGTTCAACATATGAGTGGACCATTATTTATCATCGTATTACTATTTATTTT
+CTTCTGTTTAGGTTTTATCGTGCCATCATCTTCTGGATTAGCGGTATTATCAATGCCTAT
+CTTTGCACCACTAGCTGATACAGTAGGTATACCAAGATTCGTCATCGTTACGACATATCA
+ATTTGGTCAATATGCGATGTTATTCTTAGCGCCGACTGGACTTGTTATGGCCACACTACA
+AATGTTAAACATGCGATATTCACATTGGTTCCGATTTGTATGGCCGGTAGTTGCTTTTGT
+ATTGATTTTCGGTGGCGGAGTACTAATTACGCAAGTACTAATTTATTCATAATTTGAAAT
+GCTATATTATAAAAATACTAATTGGGTTTTATGCATCTCGTAGGTTTGTAGAAATACTAA
+ACTAAGCGAGGTGCATTATTATTTTTGATTAAGAAAATAATGACGGTAATGATAACACTA
+GTAAGTAATTGATACAATGCTCTATTTAATAATGATATTTTTAAAATTTGTTTTTAATGT
+AATGTTAGATCTATGGTATATTATATTTATCGTGGTAAATATGTATTTGCTGTAAACAGT
+TTTTGTAACACATGACACATATGGTTGTGAAAATAGCATATATAAAGGATGGCTATAAAT
+GACACATTTGACAAAGGTTTTAGATACACTAACTGGAATATGCGTAGTATTATTATTTAG
+TAAATATTTTGTGGCGTATGCAAATATGGTGTTTGATTGGAATTTAAGATGGTATTTGCT
+AGAAAACATACCACATTTGCCAATTATATTATTTATTCTGATGTTTATTTTCGGAGTACC
+TTCTGAAATGATAAAAGATAGGCAAAGGAAAAATAACGGTGTTTAATTTATCGATATTTA
+GAGGTGATAAAATTTGTCAACTATTACAAAGACTAAAATAAAAATCTTTATTAATTATTT
+TATTGGTATATTAGCCTTGGCGTTTGCTGCTTATATATTATTTAAATAAAGGTTAGAGTG
+AAACGTGTTTATGAACTAGACGTTCTAGTATAGTTACTACAGCTTTAGTCAGAAGGTATC
+ATTGATAAGATCATATTAAATCAAAGAGGCATTGATATACACTAAAAAGAGGCAAGATTA
+CCTGCCTCTTTTTTAGTTATTAAATATGCGTGTTAATTCTTGGTAATAGTGTTACTGAGA
+CGCATTACGAAGAAATTTATCTTGATTTTCCTTTTTTAAAAAGAAGTGAAGATATCCTAT
+AAAGACTCTAAGTACTATTACAGTGGCTAATAACACTTCGATAAACAAAAGACCTTTCCA
+AATATCTGGAAACATAAGTACAGGCAAACTGTTCTTTAAAGCAGTTGCTGAGATTACTAA
+AGGGAATGTGAAAGCTGAAAATACGGGCGAAAAAGGTTCTTTTAGTAATTTAGGCAATTG
+TATAATGATATAAAAATAAAATATTTGAGCTAATATTAAAAATATAATTACGATAAAAGC
+ATTCGCCTTAGGAAAGGCTATAACATATGCTGCAGCGACTAAAGAAAATGGTGCACAAAT
+TGTCGATGTGTTCGGTTTGATTGACGTCTGCAATGGAAATGCTTTTAATCGCTTGAAAAC
+AATAGGTAAGACAATACAAGTAGCTACAAAGCCATATATTACTGTTAATTGACCTATGAA
+AAAACATCCGCTAACGGGTGCCGTCAATCCTGCGATAGCAATACCAATAAAAAGTACAGT
+CCACGAAGGATAAACATTTTCAAGTGAAAAATCTTTTAAATATTTTATTGAAAAAATAAT
+CATATGCGTCATAATTCCCACAAGGCATAAAATCCAAATAGGCGTTATTAAGCTATTGAT
+AAAAGTTATGTTACTAAAAAATGTATTTAAATAAGTAGTACCTAAAAAGCCAGACATGAA
+AAATGTTGTGAACACTGATGAAACTAGAGGACTGTTTAATTGTTCTTTCACATTATTAAA
+ATATTTGATCATAGTACATAAAAGGTGAATCCAAATCAAGAAAGCAAAGATTCCGCAAAC
+AGCGTTTAAAGTAAGAGATAAGTCTTTTAATAGATTACCCAGGCCTAATAATCCTAAGAC
+TAGTCCTGACGTTACTAGAGGTGCTTTTTGAAGTCTCATGATTTACAACCTTTCTTATGT
+GATTTTCTTCACTAATTATATCATGATAGCTATGGCCAATTAATAAGAAGAGTGTGTACT
+ATTACGTTATTAGAGTATGTATATTGGATTGATAGACACATAATTGACATTTAAATCTCA
+AAATTAATGATATTTGAGGTATGCTTTGCAACCTAAATATTGGAATATGTGGAAAAGTAA
+TTATTTAATTTAAATGATGATTGAAGATTTACAAGGGGGTGTACAAAATGAGAAATCAAA
+TTCAAAAACTATTAGACAGTGATTTGAGCAGTTTACATATATCGAAACAAACAGGAGTTC
+CACAAAGCACAATACACAGAATGAGAAAAAAAGAAAGATCATTAGACAATATGTCATTGA
+AAAACGCTGAACTACTTTATAAATTTGCCAATAGTATATTTAGCAATGAAAATTAAGAAG
+AATAATTAGTGAGTTAAATAATTAAAAAACCACGTCTCGATGGACGTGGTTATTTTTTTA
+AATGTATTTAATTATAGGATTTCGGGCCCCTGAAAAGTCCCTAAAATTTTGAATAGTATC
+AAAATCTATAGGAATAATATAATAATAAAAATCTCTACGCATGCAAATGGTGAGTGTTAA
+AAATCTTGGTGTAGTGTTGGTGTAGTTCAGGTGCAGTATAGATGAAATTTGAGCACAAAA
+TTACTTAATTAAAAATGTATAAACAAGTGTCAGACGCGTGTCAATTGTGTGTCAAAAAAT
+TCTATGACGAATAAGCATGCTTGTTTTAATTACTGTATTTTCGGGGCTTATGCGGGGGAC
+GTTTTGGTGACGCATCATACTATATTACTGAAATTCAAAACAAAAAGAGCCCCGTAATCA
+CGGAACTCTTTTGTTTGGTAATGCGTATAAAAATACCTATAAACGTCCTGGGAGGGATTC
+GAACCCCCGACCGATGGCTTAGAAGGCCATTGCTCTATCCAGCTGAGCTACCAGGACACG
+TTTAACAACACAAGAATTATTATATCTAAATGAACTTAAATTAGCAATACCTTGTAAATA
+AAAAATGTTTATATTTTTCACTATTATAGAGCTATTTATCTAAAAAGGTTCAATAAGACT
+TAAATGCGAATTCAGGCAACTTAATTGTGTTAAATACAGTTTTGAATGCCTAACTGTATT
+TCTTTTCTCTTTAAAATACAGTTAAGTACATTATAAGATGTTGTGCGGATAAACAAACTA
+ATTGCATCAAATTTATTTTAAAATAACAACAACAAAACGTTAAGCGAATAACATTTCGGT
+GATTTAAAAGCTACGCACGTTTTTGTTATCTTCAAATTTAAATTTTAAGGAGTGTTTTCA
+ATGGAAGGTTTATTTAACGCAATTAAAGATACCGTAACTGCAGCAATTAATAATGATGGC
+GCAAAATTAGGCACAAGCATTGTGAGCATCGTTGAAAATGGCGTAGGTTTATTAGGTAAA
+TTATTCGGATTCTAATTTCAATATGTTATGTAAGTAATCAGTATTATTTCAAAGGTGAGG
+GAGAGATTTAAATGACTGGACTAGCAGAAGCAATCGCAAATACTGTGCAAGCTGCACAAC
+AACATGATAGTGTGAAATTAGGCACAAGTATCGTAGACATCGTTGCTAACGGTGTGGGTT
+TACTAGGTAAATTATTTGGATTCTAATATAATAACTAATATTCTTTAAAATAAACTGGGT
+GAGCATACTTTAATGTTATGCACTCAGTTTATTTTATTTGCAGAAATTTGAGCCTCTGTT
\ No newline at end of file
diff --git a/t/data/reformat_input_gffs/query_1.gff b/t/data/reformat_input_gffs/query_1.gff
new file mode 100644
index 0000000..c8a0672
--- /dev/null
+++ b/t/data/reformat_input_gffs/query_1.gff
@@ -0,0 +1,220 @@
+##gff-version 3
+##sequence-region abc|SC|contig000001 1 15000
+abc|SC|contig000001 Prodigal:2.60 CDS 172 1131 . - 0 ID=1_1;gene=different;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:Q2G1X0,protein motif:TIGRFAMs:TIGR01002,protein motif:Pfam:PF07968.6;locus_tag=abc_00001;product=Alpha-toxin,beta-channel forming cytolysin,Leukocidin/Hemolysin toxin family protein;protein_id=gnl|SC|abc_00001
+abc|SC|contig000001 Prodigal:2.60 CDS 1804 1950 . + 0 ID=abc_00002;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00002;product=hypothetical protein;protein_id=gnl|SC|abc_00002
+abc|SC|contig000001 Prodigal:2.60 CDS 1934 2131 . + 0 ID=abc_00003;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00003;product=hypothetical protein;protein_id=gnl|SC|abc_00003
+abc|SC|contig000001 Prodigal:2.60 CDS 2621 3337 . - 0 ID=abc_00004;inference=ab initio prediction:Prodigal:2.60,protein motif:CLUSTERS:PRK13350,protein motif:Pfam:PF02876.11;locus_tag=abc_00004;product=superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00004
+abc|SC|contig000001 Prodigal:2.60 CDS 3445 4170 . - 0 ID=1_2;gene=speH;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P0C0I6,protein motif:CLUSTERS:PRK13349,protein motif:Pfam:PF02876.11;locus_tag=abc_00005;note=SPE H;product=hypothetical protein,superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00005
+##FASTA
+>abc|SC|contig000001
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
+ATACCCACCACATTTGGTGGAGAACCAAAAATTAGCCGAAAAACATCATTTCTGAAGTTA
+TCGGCTAAAGTTATAAATTATATTTATTTGTACATGAACAAATAATTTACATTAATTTGT
+CATTTCTTCTTTTTCCCAATCGATTTTATATCTTTCTGAAGAACGATCTGTCCATTTATC
+TTTAGTATTGGTACCTTTCCAATTTGTTGAAGTCCAATGCAATTGGTAGTCATCACGAAC
+TCGTTCGTATATTACATCTATATTTGTTTGTTGTTTGGATGCTTTTCTATCCATAGTAAT
+AACTGTAGCGAAGTCTGGTGAAAACCCTGAAGATAATAGAGAACTTGCTTTGTTAGGATC
+AAGGAAGTTCTCTGCTGCTTTCATAGAACCATTTCTAGTTTTCATGAAAAGTTGATTGCC
+ATATACCGGGTTCCAAGAATCTCTATCATATGGTCCCCAATTTTGATTCACCATATTGTT
+AAATATCACTTTCCAGCCTACTTTTTTATCAGTTGGGCTCTCTAAAATTGTTTTGAAATC
+AGGTTGAACATATTTCAGTGTATGACCAATCGAAACATTTGCACCAATAAGGCCGCCAAT
+TTTTCCTGTATCATCACCAGTAACATTACCGTTGAATCCATAAGTTAAAGTACTCATATA
+CTCTTTTGTATCAATCGAATTTCTTGGATAGTAATCAGATATTTGAGCTACTTCATTATC
+AGGTAGTTGCAACTGTACCTTAAAGGCTGAAGGCCAGGCTAAACCACTTTTGTTAGCACC
+TTCTTCGCTATAAACTCTATATTGACCAGCAATGGTACCTTTCGTTCTAATAACTAGCAG
+TTTTTTATTGTGATTTTTATCATCGATAAAACTATAAAATACTTTTTTGTGCATGCCATT
+TTCTTTATCATAAGTGACTAAATCACCTGTTTTTACTGTAGTATTGCTTCCAATATCTGT
+AGTACCGGTTTTAATATTAATATCAGAATCTGCGGCATTAGCGACAGGATTCATTAATAT
+GGAACCTAGCAATAGTGTTGTTGTTACTGAGCTGACTATACGTGTTTTCATTTTCATCAT
+CCTTCTATTTTTTTTAACGATTTGAGGAAACAATAATCAATATGTCAATTTAGAATATTG
+CAGTTGAGACATATCAAATATTTATAATCGTTTATATTAGTATATTTAATGTAGCAACTG
+ATAAATTACTGAGTGATGATGAGTGATTATTTTAAGAATATGTTTTTAACTTTTATTTAA
+AATTTGAAAGGAAGCATTTCAATTTCGAGGGTTAGTCAAAGTTGAATAAATTCTTTATGA
+AACAAGGAAAAGACATAGCTAATTTTATTGATTAATTTCTTTAAAACTAATGATTTGTTT
+GATTTAAAAATGTAATCGATTACAATATAAAAATACAAATATCTTAGAATTAAATCAATT
+AATTAACTATTAAATAAAAATTAAATATATATTAACTACTGTAAATTAATAAATAGAAAT
+AGAGAAAAAGGGTATTAATTATGTTTGGAATTTCGTCGGGAATAATTTTTGCCATTACAT
+AGAAATATCTAATAGATAATGAAAAAGTATCGTATGTATTTTTAATATAGTGTAAAATAT
+CATATGTAAAATAAAATGTAGATTTTTAGTTAGAGGCATTATAAGAAAATTTTGAGTATA
+GGTTAGCTTTTAATTATGAATCTTATTGAAATTTGATTAATAAATATATGATAGGGGATT
+AAAATGAAACTATTTTATATCGTATTTCTTATTATTATATGGCTGAATATATTTTTAGGA
+AATGAAATTATCCATACACTGACTGTTTTAATAACAACATTGTATATTGTTAATTCAAGA
+AAGGGGATTAAAAATGACAGAGTTGAATAATATTATAAACTCTCTTCAATCTTTGTTTGA
+GTCTGAATCAGGCTATAAAATTTCGAAAAATTCAGGAGTTCCATATCAAACAGTACAAGA
+TTTAAGAAATGGGAAAACCAAACTAGAAGATGCTAGATTTAGAACGATTATTAAACTTTA
+TAGTTACTATGTCTCATTAAAAGAACATTAATCATGGGACAATAAAGTATTGCTATAATA
+ATTGAATCATTAAATGAAGGAATAGAGCCTAAGACATAATAAATCAATGTCTTAGGCTCT
+ACAATATTATATTGGTAGTAGTTGACCGAATGAAAATGACCATGTAACAAGCATTTTTGG
+GGCCCCAACACAGAAGCTGACGAAAAGTCAGCTTACAATAATGTGCAAGTTGGGGATGGG
+CCCCAACACAGAGAATTTCAAAAAGAAATTCTACAGACAATGCAAGTTGGCGGGGCCCCA
+ACATAGAGAAATTCAAAAAGAAATTCTACAGACAATGCAAGTTGGGGAGTGACAACGAAA
+TAAATTTTATAAAATACCATTTCTGTCACATTCCTACTCCCAATTCCATTTAAATATATA
+GAAAATTTCACCTATTATATACATCATACACTTTAAAAATTATCATTTAAATAATCTGAT
+TTGGAATTAAAGTGCATGAAGTATAAGTCACCTTCATATACTAATCAAAGAGGACGTCAA
+CAGTTATTTTATTAGGATTTTTAACATAAACATTTGCTAGATCTGAATGTAATCTTTTGC
+TTAAATCAATAGTGTAGTTATTACCGCCACCGGTGATCTTAAGCTTACCTTTATTACGAT
+TTTCGGTATATAATATTTTATTTTTTATTAACGCTTCTCGTGCACGGAAATCGATTTCTT
+TCAATGTTAATACTGGTTTATTGCCTTGGTATATTTTATGCGCACCAATAATCGTTTGTA
+GTTTATCTTTGTATTGCACAAAAAGATTATAAGTTTTATCAGAAGGTTTTGCGGCTGGTG
+TAACGCCACCTGTAAATGTCTCTCTATAAGACCACCATAACTGATCAGTATCTTTGTCTT
+TTAGTCCAAACACATCTACGTAACGATCTTTTAACTGATTAATATTTCCCCAACTTTCAG
+CGCCCCATAAAGATATATGTGCTGACCATGAATATCTCTTAAGTTCAACATAAATGTTTC
+CATTATCATATTGATATAGCCATTTATTTGAAAATGAAAAATGAGGCTGTGTGTAATATT
+TAATTAATTCATTGATGTTAGTTTCATCTTGACCAATGCTATAAGCTTTAGCTTCAGAGT
+AAAAACTAAATACTGGTTTTTGATTTTGAGGTAATACAGTACCTAATAGTAATAATGTTG
+TCGTTAAAATTATATTTTTCGTGATGTTCTTACTCATTAGAACATCTCCTTTCAGAGGAA
+TCATGATACGAGGAATAAGAAATTTAAATGTGAGCGAAGTCAATATAGTATTTGCGATTA
+TTTTTATTAACTCCATTATTATTGTTAGTTTGATTTTTCGAGGATAACTTCAATTTTTGC
+ATTTTGAGGTTTTTTAACATATCTATTTGCATCAGTTGATGGCAACCTTTTACTTAAATC
+TATTGTGTAGTTATTGTCTGTACCTGTTATTTTAATTTGTCCTTTATTATAAGAATTATT
+ATATAATTTTTTACTTTTAATTAATGTTTGACGAATACGAAAATCTAATTCTTTTAAAGT
+TAAAACAGGCTTATTGCCTTCATAAACTGGAAATCCGCCAGTAAACGTTTCTGCTTTATC
+TTTATATGTTACATTCAGTTTATAGTGTTTATCGTTAGATGTTGCTGCAGGAGTAACACC
+ACCAGTAAACGTTTCTTGAGATAATGCAAAAGAATCAATGGTTTCTTGGTCTTTTATGCC
+AAAAATATCAACGCTTTTATTTCTTAATTGGTTGATATTGCCCCAACTTTCAGGTCCATA
+AACTTGAATATGACTATACCAAGAAAACTGTAACAACGTTGCATGAATCGTACCGTTATC
+TTTTTGCCATAACGTACTGTTAGAGAAGGTTAAATATTTTTGCGAGTAATATTTAGTTAA
+CTCATTAACGTTAGTTTCGTTTTGATTTATATAATAAGCTTTCGCTTCAGATGAAGAATT
+GATAGGTGTATTAGGAAATTGTGTAAATGCTGTACCTAATAGTAACAATGTTGTTGATAA
+AATAATTTTTTTCGTGATGTTATTGTTCATTCGAATTTCTCCTTTGAGTATTGTTGGAAT
+GTTTAATTATAAAAAGGGGTTAATTAGATAATTGAAATTATCCGCATTTACAAAAGGTAA
+TAGGTTAGTTAGATTTTTCGAGTATGACTTCAATTTGTGCATTTTTAGGATTTTTAACAT
+AACGGTTTGTGTCAGTTAATTTTAACTTTTTACTTAAATCAATCGTGTAATTATTTCCAT
+CAGCAGTTATCTTAATTTGACCTTTATTAAATTCTCCGTTATATAACTTTTTATTCTTTA
+TTAATGTTTGACGAATACGGAAATCTAATTCTTTTAAAGTTAATACTGGTTTATTTCCTT
+TGTAAAATTCATGTCCACCGATGATAGTTTGTTGTTTATCACTATATTTTAAAAATAGTC
+TATAAGGTTTATCAGATGAAGTAGCTGCTGGCGTAACACCACCAGTAAATGTTTCATCAT
+AAGTCCAGTAACCTTCAACTGTGTCCTCATCTTTAGTTCCAAATATATCAACGTATTTAT
+TTCTTAACTGATTAATGTTTCCCCAACTCTCGGATCCAAACACTTGAATATGACTATACC
+AAACCCACGTTTGCAATGTTGCATGAATGCTACCATTGGGCTTTTGCCATAGCCATTTTC
+CAGATAATGAAAAATGCGGCTGAGTGTAATATTTGATTAACTCATTGATATTAGTCTCGT
+TTTCACTGATATTATAGGCTTTTGCTTCAGATGAAAAACTGATTGGTGTTTTAGGAAGTT
+GTGTTGATGTGGTTCCTAAAAGTAACAATGCTGTTGATAAAACTAATTTATTCATGATGT
+TCTTTTTCATATGAAAATCTCCTTTGCGTGAATTACCCAAAGTATATAAGCTATTACACC
+GATTCGGAATTAAATAAAAGCTAAAACTATGTTAAATAAACTTAAACAGTTAGTAGTGTT
+ATTTAAGCAAAACTTATCATTTTTAAGTTTTGGACAGAAACAGTACTTAATAAAGTAGGC
+GGGAGTTATATATTAAAAACGACACGTTACAATTATTCTCTAATCAATTGCATTAAATTG
+TTTGATAATTGAATTTTCTAACTACTTGAAAAATAGTTATACTTTAAATGTAGTACTTAT
+TTTAATTATTTCCTACTACTTAAATTTAATATTAATAAAATGTTCATTTAATTATTGATA
+AAATATTACAAATTTTAATAGTAGGTTGTGTTTATTTTGTATGCGCTTACAATTTAGGTG
+TAACTAAAATAAAAGGAGTTGTTATTAATGAAAAATTTACGAAACAGAAGTTTTTTAACT
+TTATTAGACTTTTCACGACAAGAGGTAGAATTCTTATTAACACTCTCCGAGGATTTAAAA
+CGTGCTAAATATATTGGCACTGAAAAGCCTATGTTAAAAAATAAAAATATTGCACTGTTA
+TTTGAAAAAGATTCTACAAGAACGCGATGTGCATTTGAAGTTGCAGCGCATGATCAAGGT
+GCAAATGTAACTTATTTAGGCCCAACTGGATCACAAATGGGTAAAAAAGAAACAACTAAA
+GATACTGCACGTGTGCTTGGTGGAATGTATGATGGCATTGAATACCGTGGTTTTTCACAA
+AGAACAGTAGAAACTTTAGCTGAAAATTCAGGCGTACCAGTGTGGAATGGTTTAACTGAT
+GAAGATCATCCTACTCAAGTTCTTGCTGATTTCTTAACAGCAAAAGAAGTCTTAAAAAAA
+GATTATGCAGATATTAACTTTACATATGTTGGAGATGGTCGTAATAACGTTGCAAATGCA
+TTAATGCAAGGTGCTGCCATTATGGGTATGAACTTCCATTTAGTTTGTCCAAAAGAATTA
+AATCCAACAGATGAATTATTAAATCGCTGTAAAAATATTGCCGCTGAAAATGGTGGCAAC
+ATATTAATCACAGATGATATTGACCAAGGTGTAAAAGGTTCGGATGTAATTTACACTGAT
+GTTTGGGTATCAATGGGTGAACCTGATGAAGTATGGAAAGAACGACTTGAATTATTGAAA
+CCATATCAAGTAAATAAAGAAATGATGGATAAAACTGGTAATCCAAATGTTATTTTTGAG
+CATTGCTTACCATCTTTCCATAATGCTGATACGAAAATTGGTCAACAAATTTTTGAAAAA
+TATGGTATTCGAGAAATGGAAGTTACAGATGAAGTATTCGAAAGTAAAGCTTCAGTTGTA
+TTCCAAGAAGCTGAGAACAGAATGCATACAATCAAAGCAGTCATGGTTGCTACATTGGGT
+GAATTTTAAATGATATAAGGAAGTGAATATGATGGCGAAAATAGTAGTAGCATTAGGTGG
+TAATGCTTTAGGAAAATCACCTCAAGAACAACTCGAGCTTGTTAAAAATACTGCGAAATC
+ATTAGTAGGATTAATAACAAAAGGACATGAGATTGTTATTAGTCATGGTAATGGACCACA
+GGTTGGAAGCATTAATTTGGGACTTAACTATGCTGCAGAACATAACCAAGGTCCGGCATT
+TCCATTTGCTGAATGTGGCGCAATGAGTCAAGCTTACATCGGCTATCAATTACAAGAAAG
+CTTACAAAATGAATTGCATTCTATTGGAATGGATAAACAAGTGGTAACACTAGTGACACA
+AGTTGAAGTTGATGAAAATGATCCGGCATTTAACAATCCTTCAAAACCAATTGGGTTATT
+TTACAACAAAGAAGAAGCTGAACAAATTCAAAAAGAAAAAGGATTTATATTTGTTGAAGA
+TGCTGGAAGAGGATATAGACGCGTTGTTCCTTCACCACAACCCATCTCTATTATTGAATT
+AGAGAGTATTAAAACACTTATTAAAAATGATACACTCGTTATTGCTGCTGGTGGTGGAGG
+TATACCAGTAATTAGAGAGCAACATGATGGTTTTAAAGGTATTGATGCAGTTATAGACAA
+AGATAAAACAAGTGCGTTGTTGGGTGCTAATATTCAATGCGATCAATTGATTATTTTAAC
+AGCAATTGATTATGTATATATTAATTTTAACACTGAAAACCAACAGCCTTTGAAAACAAC
+AAATGTTGATGAATTAAAACGATATATAGACGAAAATCAATTTGCAAAAGGAAGTATGTT
+ACCAAAAATTGAAGCAGCCATATCATTTATTGAAAACAATCCAAAAGGAAGTGTGCTTAT
+AACATCATTAAATGAATTAGATGCTGCCTTAGAGGGTAAAGTAGGTACTGTGATTAAAAA
+GTAATTGAATTGAAACGCTTTTCAATTACTATATGTCAAATGCATGATTTTTATTATTTA
+TGTGCACCCCCTGAAAATAATGCCTCTATTTTGATGCGGGGTGCACTTTCTTAATTTATA
+TTTATAAAATCTTTAAGGTAGAAATGCTAGGTTAAATGTCGAAGGAGATGAAACCGTGGA
+AAATACAATTAATGAAAGTGAAAAGAAAAAACGATTTAAATTAAAAATGCCAGGTGCATT
+TATGATTTTATTCATTTTAACGGTTGTTGCAGTTATAGCAACATGGGTTATTCCTGCTGG
+TGCATATTCTAAACTTTCTTACGAACCTTCATCCCAAGAACTAAAGATAGTTAACCCTCA
+TAACCAAGTGAAAAAGGTTCCGGGTACGCAACAGGAACTAGACAAAATGGGGGTTAAAAT
+TAAGATTGAACAATTTAAATCAGGTGCAATTAATAAGCCAGTATCAATTCCGAATACTTA
+TGAAAGATTAAAGCAACATCCAGCTGGACCAGAACAAATAACAAGTAGCATGGTTGAAGG
+TACGATAGAAGCGGTCGATATCATGGTATTCATTCTTGTACTAGGGGGACTTATTGGCGT
+AGTTCAAGCCAGTGGTTCTTTTGAATCGGGATTGTTAGCTTTAACGAAGAAAACAAAAGG
+GCATGAATTTATGCTAATTGTGTTTGTATCAATACTAATGATTATCGGCGGGACGTTATG
+TGGTATTGAAGAAGAAGCTGTAGCATTCTATCCGATTTTAGTCCCTATATTTATAGCGTT
+AGGATACGATTCTATCGTTTCAGTTGGTGCCATATTCCTTGCCAGCTCTGTCGGTAGTAC
+ATTTTCAACTATTAACCCGTTCTCGGTTGTAATTGCCTCTAATGCCGCTGGTACAACTTT
+TACGGATGGCTTGTATTGGAGAATAGGTGCTTGTATTGTCGGTGCGATTTTTGTTATTAG
+TTATTTATATTGGTACTGTAAAAAAATTAAAAACGATCCTAAAGCGTCATATTCTTATGA
+AGACAAAGATGCTTTTGAACAGCAATGGTCTGTATTAAAAGATGACGATAGTGCCCATTT
+TACTTTGCGTAAGAAGATAATCCTTACATTATTTGTACTACCATTTCCAATTATGGTATG
+GGGAGTTATGACGCAAGGTTGGTGGTTCCCAGTTATGGCTTCAGCATTTTTAATATTTAC
+AATTATAATAATGTTTATTGCTGGGACAGGTAAATCTGGATTGGGAGAAAAAGGAACTGT
+AGATGCATTTGTCAATGGTGCATCAAGTTTAGTAGGTGTATCTTTAATTATTGGTTTAGC
+TCGAGGTATTAATTTAGTGTTGAATGAAGGTATGATTTCAGATACAATCTTACACTTTTC
+ATCATCTTTAGTTCAACATATGAGTGGACCATTATTTATCATCGTATTACTATTTATTTT
+CTTCTGTTTAGGTTTTATCGTGCCATCATCTTCTGGATTAGCGGTATTATCAATGCCTAT
+CTTTGCACCACTAGCTGATACAGTAGGTATACCAAGATTCGTCATCGTTACGACATATCA
+ATTTGGTCAATATGCGATGTTATTCTTAGCGCCGACTGGACTTGTTATGGCCACACTACA
+AATGTTAAACATGCGATATTCACATTGGTTCCGATTTGTATGGCCGGTAGTTGCTTTTGT
+ATTGATTTTCGGTGGCGGAGTACTAATTACGCAAGTACTAATTTATTCATAATTTGAAAT
+GCTATATTATAAAAATACTAATTGGGTTTTATGCATCTCGTAGGTTTGTAGAAATACTAA
+ACTAAGCGAGGTGCATTATTATTTTTGATTAAGAAAATAATGACGGTAATGATAACACTA
+GTAAGTAATTGATACAATGCTCTATTTAATAATGATATTTTTAAAATTTGTTTTTAATGT
+AATGTTAGATCTATGGTATATTATATTTATCGTGGTAAATATGTATTTGCTGTAAACAGT
+TTTTGTAACACATGACACATATGGTTGTGAAAATAGCATATATAAAGGATGGCTATAAAT
+GACACATTTGACAAAGGTTTTAGATACACTAACTGGAATATGCGTAGTATTATTATTTAG
+TAAATATTTTGTGGCGTATGCAAATATGGTGTTTGATTGGAATTTAAGATGGTATTTGCT
+AGAAAACATACCACATTTGCCAATTATATTATTTATTCTGATGTTTATTTTCGGAGTACC
+TTCTGAAATGATAAAAGATAGGCAAAGGAAAAATAACGGTGTTTAATTTATCGATATTTA
+GAGGTGATAAAATTTGTCAACTATTACAAAGACTAAAATAAAAATCTTTATTAATTATTT
+TATTGGTATATTAGCCTTGGCGTTTGCTGCTTATATATTATTTAAATAAAGGTTAGAGTG
+AAACGTGTTTATGAACTAGACGTTCTAGTATAGTTACTACAGCTTTAGTCAGAAGGTATC
+ATTGATAAGATCATATTAAATCAAAGAGGCATTGATATACACTAAAAAGAGGCAAGATTA
+CCTGCCTCTTTTTTAGTTATTAAATATGCGTGTTAATTCTTGGTAATAGTGTTACTGAGA
+CGCATTACGAAGAAATTTATCTTGATTTTCCTTTTTTAAAAAGAAGTGAAGATATCCTAT
+AAAGACTCTAAGTACTATTACAGTGGCTAATAACACTTCGATAAACAAAAGACCTTTCCA
+AATATCTGGAAACATAAGTACAGGCAAACTGTTCTTTAAAGCAGTTGCTGAGATTACTAA
+AGGGAATGTGAAAGCTGAAAATACGGGCGAAAAAGGTTCTTTTAGTAATTTAGGCAATTG
+TATAATGATATAAAAATAAAATATTTGAGCTAATATTAAAAATATAATTACGATAAAAGC
+ATTCGCCTTAGGAAAGGCTATAACATATGCTGCAGCGACTAAAGAAAATGGTGCACAAAT
+TGTCGATGTGTTCGGTTTGATTGACGTCTGCAATGGAAATGCTTTTAATCGCTTGAAAAC
+AATAGGTAAGACAATACAAGTAGCTACAAAGCCATATATTACTGTTAATTGACCTATGAA
+AAAACATCCGCTAACGGGTGCCGTCAATCCTGCGATAGCAATACCAATAAAAAGTACAGT
+CCACGAAGGATAAACATTTTCAAGTGAAAAATCTTTTAAATATTTTATTGAAAAAATAAT
+CATATGCGTCATAATTCCCACAAGGCATAAAATCCAAATAGGCGTTATTAAGCTATTGAT
+AAAAGTTATGTTACTAAAAAATGTATTTAAATAAGTAGTACCTAAAAAGCCAGACATGAA
+AAATGTTGTGAACACTGATGAAACTAGAGGACTGTTTAATTGTTCTTTCACATTATTAAA
+ATATTTGATCATAGTACATAAAAGGTGAATCCAAATCAAGAAAGCAAAGATTCCGCAAAC
+AGCGTTTAAAGTAAGAGATAAGTCTTTTAATAGATTACCCAGGCCTAATAATCCTAAGAC
+TAGTCCTGACGTTACTAGAGGTGCTTTTTGAAGTCTCATGATTTACAACCTTTCTTATGT
+GATTTTCTTCACTAATTATATCATGATAGCTATGGCCAATTAATAAGAAGAGTGTGTACT
+ATTACGTTATTAGAGTATGTATATTGGATTGATAGACACATAATTGACATTTAAATCTCA
+AAATTAATGATATTTGAGGTATGCTTTGCAACCTAAATATTGGAATATGTGGAAAAGTAA
+TTATTTAATTTAAATGATGATTGAAGATTTACAAGGGGGTGTACAAAATGAGAAATCAAA
+TTCAAAAACTATTAGACAGTGATTTGAGCAGTTTACATATATCGAAACAAACAGGAGTTC
+CACAAAGCACAATACACAGAATGAGAAAAAAAGAAAGATCATTAGACAATATGTCATTGA
+AAAACGCTGAACTACTTTATAAATTTGCCAATAGTATATTTAGCAATGAAAATTAAGAAG
+AATAATTAGTGAGTTAAATAATTAAAAAACCACGTCTCGATGGACGTGGTTATTTTTTTA
+AATGTATTTAATTATAGGATTTCGGGCCCCTGAAAAGTCCCTAAAATTTTGAATAGTATC
+AAAATCTATAGGAATAATATAATAATAAAAATCTCTACGCATGCAAATGGTGAGTGTTAA
+AAATCTTGGTGTAGTGTTGGTGTAGTTCAGGTGCAGTATAGATGAAATTTGAGCACAAAA
+TTACTTAATTAAAAATGTATAAACAAGTGTCAGACGCGTGTCAATTGTGTGTCAAAAAAT
+TCTATGACGAATAAGCATGCTTGTTTTAATTACTGTATTTTCGGGGCTTATGCGGGGGAC
+GTTTTGGTGACGCATCATACTATATTACTGAAATTCAAAACAAAAAGAGCCCCGTAATCA
+CGGAACTCTTTTGTTTGGTAATGCGTATAAAAATACCTATAAACGTCCTGGGAGGGATTC
+GAACCCCCGACCGATGGCTTAGAAGGCCATTGCTCTATCCAGCTGAGCTACCAGGACACG
+TTTAACAACACAAGAATTATTATATCTAAATGAACTTAAATTAGCAATACCTTGTAAATA
+AAAAATGTTTATATTTTTCACTATTATAGAGCTATTTATCTAAAAAGGTTCAATAAGACT
+TAAATGCGAATTCAGGCAACTTAATTGTGTTAAATACAGTTTTGAATGCCTAACTGTATT
+TCTTTTCTCTTTAAAATACAGTTAAGTACATTATAAGATGTTGTGCGGATAAACAAACTA
+ATTGCATCAAATTTATTTTAAAATAACAACAACAAAACGTTAAGCGAATAACATTTCGGT
+GATTTAAAAGCTACGCACGTTTTTGTTATCTTCAAATTTAAATTTTAAGGAGTGTTTTCA
+ATGGAAGGTTTATTTAACGCAATTAAAGATACCGTAACTGCAGCAATTAATAATGATGGC
+GCAAAATTAGGCACAAGCATTGTGAGCATCGTTGAAAATGGCGTAGGTTTATTAGGTAAA
+TTATTCGGATTCTAATTTCAATATGTTATGTAAGTAATCAGTATTATTTCAAAGGTGAGG
+GAGAGATTTAAATGACTGGACTAGCAGAAGCAATCGCAAATACTGTGCAAGCTGCACAAC
+AACATGATAGTGTGAAATTAGGCACAAGTATCGTAGACATCGTTGCTAACGGTGTGGGTT
+TACTAGGTAAATTATTTGGATTCTAATATAATAACTAATATTCTTTAAAATAAACTGGGT
+GAGCATACTTTAATGTTATGCACTCAGTTTATTTTATTTGCAGAAATTTGAGCCTCTGTT
\ No newline at end of file
diff --git a/t/data/reformat_input_gffs/query_2.gff b/t/data/reformat_input_gffs/query_2.gff
new file mode 100644
index 0000000..d429f62
--- /dev/null
+++ b/t/data/reformat_input_gffs/query_2.gff
@@ -0,0 +1,220 @@
+##gff-version 3
+##sequence-region abc|SC|contig000001 1 15000
+abc|SC|contig000001 Prodigal:2.60 CDS 172 1131 . - 0 ID=1_1;gene=different;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:Q2G1X0,protein motif:TIGRFAMs:TIGR01002,protein motif:Pfam:PF07968.6;locus_tag=abc_00001;product=Alpha-toxin,beta-channel forming cytolysin,Leukocidin/Hemolysin toxin family protein;protein_id=gnl|SC|abc_00001
+abc|SC|contig000001 Prodigal:2.60 CDS 1804 1950 . + 0 ID=abc_00002;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00002;product=hypothetical protein;protein_id=gnl|SC|abc_00002
+abc|SC|contig000001 Prodigal:2.60 CDS 1934 2131 . + 0 inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00003;ID=abc_00003;product=hypothetical protein;protein_id=gnl|SC|abc_00003
+abc|SC|contig000001 Prodigal:2.60 CDS 2621 3337 . - 0 ID=abc_00004;inference=ab initio prediction:Prodigal:2.60,protein motif:CLUSTERS:PRK13350,protein motif:Pfam:PF02876.11;locus_tag=abc_00004;product=superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00004
+abc|SC|contig000001 Prodigal:2.60 CDS 3445 4170 . - 0 gene=speH;ID=1_2;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P0C0I6,protein motif:CLUSTERS:PRK13349,protein motif:Pfam:PF02876.11;locus_tag=abc_00005;note=SPE H;product=hypothetical protein,superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00005
+##FASTA
+>abc|SC|contig000001
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
+ATACCCACCACATTTGGTGGAGAACCAAAAATTAGCCGAAAAACATCATTTCTGAAGTTA
+TCGGCTAAAGTTATAAATTATATTTATTTGTACATGAACAAATAATTTACATTAATTTGT
+CATTTCTTCTTTTTCCCAATCGATTTTATATCTTTCTGAAGAACGATCTGTCCATTTATC
+TTTAGTATTGGTACCTTTCCAATTTGTTGAAGTCCAATGCAATTGGTAGTCATCACGAAC
+TCGTTCGTATATTACATCTATATTTGTTTGTTGTTTGGATGCTTTTCTATCCATAGTAAT
+AACTGTAGCGAAGTCTGGTGAAAACCCTGAAGATAATAGAGAACTTGCTTTGTTAGGATC
+AAGGAAGTTCTCTGCTGCTTTCATAGAACCATTTCTAGTTTTCATGAAAAGTTGATTGCC
+ATATACCGGGTTCCAAGAATCTCTATCATATGGTCCCCAATTTTGATTCACCATATTGTT
+AAATATCACTTTCCAGCCTACTTTTTTATCAGTTGGGCTCTCTAAAATTGTTTTGAAATC
+AGGTTGAACATATTTCAGTGTATGACCAATCGAAACATTTGCACCAATAAGGCCGCCAAT
+TTTTCCTGTATCATCACCAGTAACATTACCGTTGAATCCATAAGTTAAAGTACTCATATA
+CTCTTTTGTATCAATCGAATTTCTTGGATAGTAATCAGATATTTGAGCTACTTCATTATC
+AGGTAGTTGCAACTGTACCTTAAAGGCTGAAGGCCAGGCTAAACCACTTTTGTTAGCACC
+TTCTTCGCTATAAACTCTATATTGACCAGCAATGGTACCTTTCGTTCTAATAACTAGCAG
+TTTTTTATTGTGATTTTTATCATCGATAAAACTATAAAATACTTTTTTGTGCATGCCATT
+TTCTTTATCATAAGTGACTAAATCACCTGTTTTTACTGTAGTATTGCTTCCAATATCTGT
+AGTACCGGTTTTAATATTAATATCAGAATCTGCGGCATTAGCGACAGGATTCATTAATAT
+GGAACCTAGCAATAGTGTTGTTGTTACTGAGCTGACTATACGTGTTTTCATTTTCATCAT
+CCTTCTATTTTTTTTAACGATTTGAGGAAACAATAATCAATATGTCAATTTAGAATATTG
+CAGTTGAGACATATCAAATATTTATAATCGTTTATATTAGTATATTTAATGTAGCAACTG
+ATAAATTACTGAGTGATGATGAGTGATTATTTTAAGAATATGTTTTTAACTTTTATTTAA
+AATTTGAAAGGAAGCATTTCAATTTCGAGGGTTAGTCAAAGTTGAATAAATTCTTTATGA
+AACAAGGAAAAGACATAGCTAATTTTATTGATTAATTTCTTTAAAACTAATGATTTGTTT
+GATTTAAAAATGTAATCGATTACAATATAAAAATACAAATATCTTAGAATTAAATCAATT
+AATTAACTATTAAATAAAAATTAAATATATATTAACTACTGTAAATTAATAAATAGAAAT
+AGAGAAAAAGGGTATTAATTATGTTTGGAATTTCGTCGGGAATAATTTTTGCCATTACAT
+AGAAATATCTAATAGATAATGAAAAAGTATCGTATGTATTTTTAATATAGTGTAAAATAT
+CATATGTAAAATAAAATGTAGATTTTTAGTTAGAGGCATTATAAGAAAATTTTGAGTATA
+GGTTAGCTTTTAATTATGAATCTTATTGAAATTTGATTAATAAATATATGATAGGGGATT
+AAAATGAAACTATTTTATATCGTATTTCTTATTATTATATGGCTGAATATATTTTTAGGA
+AATGAAATTATCCATACACTGACTGTTTTAATAACAACATTGTATATTGTTAATTCAAGA
+AAGGGGATTAAAAATGACAGAGTTGAATAATATTATAAACTCTCTTCAATCTTTGTTTGA
+GTCTGAATCAGGCTATAAAATTTCGAAAAATTCAGGAGTTCCATATCAAACAGTACAAGA
+TTTAAGAAATGGGAAAACCAAACTAGAAGATGCTAGATTTAGAACGATTATTAAACTTTA
+TAGTTACTATGTCTCATTAAAAGAACATTAATCATGGGACAATAAAGTATTGCTATAATA
+ATTGAATCATTAAATGAAGGAATAGAGCCTAAGACATAATAAATCAATGTCTTAGGCTCT
+ACAATATTATATTGGTAGTAGTTGACCGAATGAAAATGACCATGTAACAAGCATTTTTGG
+GGCCCCAACACAGAAGCTGACGAAAAGTCAGCTTACAATAATGTGCAAGTTGGGGATGGG
+CCCCAACACAGAGAATTTCAAAAAGAAATTCTACAGACAATGCAAGTTGGCGGGGCCCCA
+ACATAGAGAAATTCAAAAAGAAATTCTACAGACAATGCAAGTTGGGGAGTGACAACGAAA
+TAAATTTTATAAAATACCATTTCTGTCACATTCCTACTCCCAATTCCATTTAAATATATA
+GAAAATTTCACCTATTATATACATCATACACTTTAAAAATTATCATTTAAATAATCTGAT
+TTGGAATTAAAGTGCATGAAGTATAAGTCACCTTCATATACTAATCAAAGAGGACGTCAA
+CAGTTATTTTATTAGGATTTTTAACATAAACATTTGCTAGATCTGAATGTAATCTTTTGC
+TTAAATCAATAGTGTAGTTATTACCGCCACCGGTGATCTTAAGCTTACCTTTATTACGAT
+TTTCGGTATATAATATTTTATTTTTTATTAACGCTTCTCGTGCACGGAAATCGATTTCTT
+TCAATGTTAATACTGGTTTATTGCCTTGGTATATTTTATGCGCACCAATAATCGTTTGTA
+GTTTATCTTTGTATTGCACAAAAAGATTATAAGTTTTATCAGAAGGTTTTGCGGCTGGTG
+TAACGCCACCTGTAAATGTCTCTCTATAAGACCACCATAACTGATCAGTATCTTTGTCTT
+TTAGTCCAAACACATCTACGTAACGATCTTTTAACTGATTAATATTTCCCCAACTTTCAG
+CGCCCCATAAAGATATATGTGCTGACCATGAATATCTCTTAAGTTCAACATAAATGTTTC
+CATTATCATATTGATATAGCCATTTATTTGAAAATGAAAAATGAGGCTGTGTGTAATATT
+TAATTAATTCATTGATGTTAGTTTCATCTTGACCAATGCTATAAGCTTTAGCTTCAGAGT
+AAAAACTAAATACTGGTTTTTGATTTTGAGGTAATACAGTACCTAATAGTAATAATGTTG
+TCGTTAAAATTATATTTTTCGTGATGTTCTTACTCATTAGAACATCTCCTTTCAGAGGAA
+TCATGATACGAGGAATAAGAAATTTAAATGTGAGCGAAGTCAATATAGTATTTGCGATTA
+TTTTTATTAACTCCATTATTATTGTTAGTTTGATTTTTCGAGGATAACTTCAATTTTTGC
+ATTTTGAGGTTTTTTAACATATCTATTTGCATCAGTTGATGGCAACCTTTTACTTAAATC
+TATTGTGTAGTTATTGTCTGTACCTGTTATTTTAATTTGTCCTTTATTATAAGAATTATT
+ATATAATTTTTTACTTTTAATTAATGTTTGACGAATACGAAAATCTAATTCTTTTAAAGT
+TAAAACAGGCTTATTGCCTTCATAAACTGGAAATCCGCCAGTAAACGTTTCTGCTTTATC
+TTTATATGTTACATTCAGTTTATAGTGTTTATCGTTAGATGTTGCTGCAGGAGTAACACC
+ACCAGTAAACGTTTCTTGAGATAATGCAAAAGAATCAATGGTTTCTTGGTCTTTTATGCC
+AAAAATATCAACGCTTTTATTTCTTAATTGGTTGATATTGCCCCAACTTTCAGGTCCATA
+AACTTGAATATGACTATACCAAGAAAACTGTAACAACGTTGCATGAATCGTACCGTTATC
+TTTTTGCCATAACGTACTGTTAGAGAAGGTTAAATATTTTTGCGAGTAATATTTAGTTAA
+CTCATTAACGTTAGTTTCGTTTTGATTTATATAATAAGCTTTCGCTTCAGATGAAGAATT
+GATAGGTGTATTAGGAAATTGTGTAAATGCTGTACCTAATAGTAACAATGTTGTTGATAA
+AATAATTTTTTTCGTGATGTTATTGTTCATTCGAATTTCTCCTTTGAGTATTGTTGGAAT
+GTTTAATTATAAAAAGGGGTTAATTAGATAATTGAAATTATCCGCATTTACAAAAGGTAA
+TAGGTTAGTTAGATTTTTCGAGTATGACTTCAATTTGTGCATTTTTAGGATTTTTAACAT
+AACGGTTTGTGTCAGTTAATTTTAACTTTTTACTTAAATCAATCGTGTAATTATTTCCAT
+CAGCAGTTATCTTAATTTGACCTTTATTAAATTCTCCGTTATATAACTTTTTATTCTTTA
+TTAATGTTTGACGAATACGGAAATCTAATTCTTTTAAAGTTAATACTGGTTTATTTCCTT
+TGTAAAATTCATGTCCACCGATGATAGTTTGTTGTTTATCACTATATTTTAAAAATAGTC
+TATAAGGTTTATCAGATGAAGTAGCTGCTGGCGTAACACCACCAGTAAATGTTTCATCAT
+AAGTCCAGTAACCTTCAACTGTGTCCTCATCTTTAGTTCCAAATATATCAACGTATTTAT
+TTCTTAACTGATTAATGTTTCCCCAACTCTCGGATCCAAACACTTGAATATGACTATACC
+AAACCCACGTTTGCAATGTTGCATGAATGCTACCATTGGGCTTTTGCCATAGCCATTTTC
+CAGATAATGAAAAATGCGGCTGAGTGTAATATTTGATTAACTCATTGATATTAGTCTCGT
+TTTCACTGATATTATAGGCTTTTGCTTCAGATGAAAAACTGATTGGTGTTTTAGGAAGTT
+GTGTTGATGTGGTTCCTAAAAGTAACAATGCTGTTGATAAAACTAATTTATTCATGATGT
+TCTTTTTCATATGAAAATCTCCTTTGCGTGAATTACCCAAAGTATATAAGCTATTACACC
+GATTCGGAATTAAATAAAAGCTAAAACTATGTTAAATAAACTTAAACAGTTAGTAGTGTT
+ATTTAAGCAAAACTTATCATTTTTAAGTTTTGGACAGAAACAGTACTTAATAAAGTAGGC
+GGGAGTTATATATTAAAAACGACACGTTACAATTATTCTCTAATCAATTGCATTAAATTG
+TTTGATAATTGAATTTTCTAACTACTTGAAAAATAGTTATACTTTAAATGTAGTACTTAT
+TTTAATTATTTCCTACTACTTAAATTTAATATTAATAAAATGTTCATTTAATTATTGATA
+AAATATTACAAATTTTAATAGTAGGTTGTGTTTATTTTGTATGCGCTTACAATTTAGGTG
+TAACTAAAATAAAAGGAGTTGTTATTAATGAAAAATTTACGAAACAGAAGTTTTTTAACT
+TTATTAGACTTTTCACGACAAGAGGTAGAATTCTTATTAACACTCTCCGAGGATTTAAAA
+CGTGCTAAATATATTGGCACTGAAAAGCCTATGTTAAAAAATAAAAATATTGCACTGTTA
+TTTGAAAAAGATTCTACAAGAACGCGATGTGCATTTGAAGTTGCAGCGCATGATCAAGGT
+GCAAATGTAACTTATTTAGGCCCAACTGGATCACAAATGGGTAAAAAAGAAACAACTAAA
+GATACTGCACGTGTGCTTGGTGGAATGTATGATGGCATTGAATACCGTGGTTTTTCACAA
+AGAACAGTAGAAACTTTAGCTGAAAATTCAGGCGTACCAGTGTGGAATGGTTTAACTGAT
+GAAGATCATCCTACTCAAGTTCTTGCTGATTTCTTAACAGCAAAAGAAGTCTTAAAAAAA
+GATTATGCAGATATTAACTTTACATATGTTGGAGATGGTCGTAATAACGTTGCAAATGCA
+TTAATGCAAGGTGCTGCCATTATGGGTATGAACTTCCATTTAGTTTGTCCAAAAGAATTA
+AATCCAACAGATGAATTATTAAATCGCTGTAAAAATATTGCCGCTGAAAATGGTGGCAAC
+ATATTAATCACAGATGATATTGACCAAGGTGTAAAAGGTTCGGATGTAATTTACACTGAT
+GTTTGGGTATCAATGGGTGAACCTGATGAAGTATGGAAAGAACGACTTGAATTATTGAAA
+CCATATCAAGTAAATAAAGAAATGATGGATAAAACTGGTAATCCAAATGTTATTTTTGAG
+CATTGCTTACCATCTTTCCATAATGCTGATACGAAAATTGGTCAACAAATTTTTGAAAAA
+TATGGTATTCGAGAAATGGAAGTTACAGATGAAGTATTCGAAAGTAAAGCTTCAGTTGTA
+TTCCAAGAAGCTGAGAACAGAATGCATACAATCAAAGCAGTCATGGTTGCTACATTGGGT
+GAATTTTAAATGATATAAGGAAGTGAATATGATGGCGAAAATAGTAGTAGCATTAGGTGG
+TAATGCTTTAGGAAAATCACCTCAAGAACAACTCGAGCTTGTTAAAAATACTGCGAAATC
+ATTAGTAGGATTAATAACAAAAGGACATGAGATTGTTATTAGTCATGGTAATGGACCACA
+GGTTGGAAGCATTAATTTGGGACTTAACTATGCTGCAGAACATAACCAAGGTCCGGCATT
+TCCATTTGCTGAATGTGGCGCAATGAGTCAAGCTTACATCGGCTATCAATTACAAGAAAG
+CTTACAAAATGAATTGCATTCTATTGGAATGGATAAACAAGTGGTAACACTAGTGACACA
+AGTTGAAGTTGATGAAAATGATCCGGCATTTAACAATCCTTCAAAACCAATTGGGTTATT
+TTACAACAAAGAAGAAGCTGAACAAATTCAAAAAGAAAAAGGATTTATATTTGTTGAAGA
+TGCTGGAAGAGGATATAGACGCGTTGTTCCTTCACCACAACCCATCTCTATTATTGAATT
+AGAGAGTATTAAAACACTTATTAAAAATGATACACTCGTTATTGCTGCTGGTGGTGGAGG
+TATACCAGTAATTAGAGAGCAACATGATGGTTTTAAAGGTATTGATGCAGTTATAGACAA
+AGATAAAACAAGTGCGTTGTTGGGTGCTAATATTCAATGCGATCAATTGATTATTTTAAC
+AGCAATTGATTATGTATATATTAATTTTAACACTGAAAACCAACAGCCTTTGAAAACAAC
+AAATGTTGATGAATTAAAACGATATATAGACGAAAATCAATTTGCAAAAGGAAGTATGTT
+ACCAAAAATTGAAGCAGCCATATCATTTATTGAAAACAATCCAAAAGGAAGTGTGCTTAT
+AACATCATTAAATGAATTAGATGCTGCCTTAGAGGGTAAAGTAGGTACTGTGATTAAAAA
+GTAATTGAATTGAAACGCTTTTCAATTACTATATGTCAAATGCATGATTTTTATTATTTA
+TGTGCACCCCCTGAAAATAATGCCTCTATTTTGATGCGGGGTGCACTTTCTTAATTTATA
+TTTATAAAATCTTTAAGGTAGAAATGCTAGGTTAAATGTCGAAGGAGATGAAACCGTGGA
+AAATACAATTAATGAAAGTGAAAAGAAAAAACGATTTAAATTAAAAATGCCAGGTGCATT
+TATGATTTTATTCATTTTAACGGTTGTTGCAGTTATAGCAACATGGGTTATTCCTGCTGG
+TGCATATTCTAAACTTTCTTACGAACCTTCATCCCAAGAACTAAAGATAGTTAACCCTCA
+TAACCAAGTGAAAAAGGTTCCGGGTACGCAACAGGAACTAGACAAAATGGGGGTTAAAAT
+TAAGATTGAACAATTTAAATCAGGTGCAATTAATAAGCCAGTATCAATTCCGAATACTTA
+TGAAAGATTAAAGCAACATCCAGCTGGACCAGAACAAATAACAAGTAGCATGGTTGAAGG
+TACGATAGAAGCGGTCGATATCATGGTATTCATTCTTGTACTAGGGGGACTTATTGGCGT
+AGTTCAAGCCAGTGGTTCTTTTGAATCGGGATTGTTAGCTTTAACGAAGAAAACAAAAGG
+GCATGAATTTATGCTAATTGTGTTTGTATCAATACTAATGATTATCGGCGGGACGTTATG
+TGGTATTGAAGAAGAAGCTGTAGCATTCTATCCGATTTTAGTCCCTATATTTATAGCGTT
+AGGATACGATTCTATCGTTTCAGTTGGTGCCATATTCCTTGCCAGCTCTGTCGGTAGTAC
+ATTTTCAACTATTAACCCGTTCTCGGTTGTAATTGCCTCTAATGCCGCTGGTACAACTTT
+TACGGATGGCTTGTATTGGAGAATAGGTGCTTGTATTGTCGGTGCGATTTTTGTTATTAG
+TTATTTATATTGGTACTGTAAAAAAATTAAAAACGATCCTAAAGCGTCATATTCTTATGA
+AGACAAAGATGCTTTTGAACAGCAATGGTCTGTATTAAAAGATGACGATAGTGCCCATTT
+TACTTTGCGTAAGAAGATAATCCTTACATTATTTGTACTACCATTTCCAATTATGGTATG
+GGGAGTTATGACGCAAGGTTGGTGGTTCCCAGTTATGGCTTCAGCATTTTTAATATTTAC
+AATTATAATAATGTTTATTGCTGGGACAGGTAAATCTGGATTGGGAGAAAAAGGAACTGT
+AGATGCATTTGTCAATGGTGCATCAAGTTTAGTAGGTGTATCTTTAATTATTGGTTTAGC
+TCGAGGTATTAATTTAGTGTTGAATGAAGGTATGATTTCAGATACAATCTTACACTTTTC
+ATCATCTTTAGTTCAACATATGAGTGGACCATTATTTATCATCGTATTACTATTTATTTT
+CTTCTGTTTAGGTTTTATCGTGCCATCATCTTCTGGATTAGCGGTATTATCAATGCCTAT
+CTTTGCACCACTAGCTGATACAGTAGGTATACCAAGATTCGTCATCGTTACGACATATCA
+ATTTGGTCAATATGCGATGTTATTCTTAGCGCCGACTGGACTTGTTATGGCCACACTACA
+AATGTTAAACATGCGATATTCACATTGGTTCCGATTTGTATGGCCGGTAGTTGCTTTTGT
+ATTGATTTTCGGTGGCGGAGTACTAATTACGCAAGTACTAATTTATTCATAATTTGAAAT
+GCTATATTATAAAAATACTAATTGGGTTTTATGCATCTCGTAGGTTTGTAGAAATACTAA
+ACTAAGCGAGGTGCATTATTATTTTTGATTAAGAAAATAATGACGGTAATGATAACACTA
+GTAAGTAATTGATACAATGCTCTATTTAATAATGATATTTTTAAAATTTGTTTTTAATGT
+AATGTTAGATCTATGGTATATTATATTTATCGTGGTAAATATGTATTTGCTGTAAACAGT
+TTTTGTAACACATGACACATATGGTTGTGAAAATAGCATATATAAAGGATGGCTATAAAT
+GACACATTTGACAAAGGTTTTAGATACACTAACTGGAATATGCGTAGTATTATTATTTAG
+TAAATATTTTGTGGCGTATGCAAATATGGTGTTTGATTGGAATTTAAGATGGTATTTGCT
+AGAAAACATACCACATTTGCCAATTATATTATTTATTCTGATGTTTATTTTCGGAGTACC
+TTCTGAAATGATAAAAGATAGGCAAAGGAAAAATAACGGTGTTTAATTTATCGATATTTA
+GAGGTGATAAAATTTGTCAACTATTACAAAGACTAAAATAAAAATCTTTATTAATTATTT
+TATTGGTATATTAGCCTTGGCGTTTGCTGCTTATATATTATTTAAATAAAGGTTAGAGTG
+AAACGTGTTTATGAACTAGACGTTCTAGTATAGTTACTACAGCTTTAGTCAGAAGGTATC
+ATTGATAAGATCATATTAAATCAAAGAGGCATTGATATACACTAAAAAGAGGCAAGATTA
+CCTGCCTCTTTTTTAGTTATTAAATATGCGTGTTAATTCTTGGTAATAGTGTTACTGAGA
+CGCATTACGAAGAAATTTATCTTGATTTTCCTTTTTTAAAAAGAAGTGAAGATATCCTAT
+AAAGACTCTAAGTACTATTACAGTGGCTAATAACACTTCGATAAACAAAAGACCTTTCCA
+AATATCTGGAAACATAAGTACAGGCAAACTGTTCTTTAAAGCAGTTGCTGAGATTACTAA
+AGGGAATGTGAAAGCTGAAAATACGGGCGAAAAAGGTTCTTTTAGTAATTTAGGCAATTG
+TATAATGATATAAAAATAAAATATTTGAGCTAATATTAAAAATATAATTACGATAAAAGC
+ATTCGCCTTAGGAAAGGCTATAACATATGCTGCAGCGACTAAAGAAAATGGTGCACAAAT
+TGTCGATGTGTTCGGTTTGATTGACGTCTGCAATGGAAATGCTTTTAATCGCTTGAAAAC
+AATAGGTAAGACAATACAAGTAGCTACAAAGCCATATATTACTGTTAATTGACCTATGAA
+AAAACATCCGCTAACGGGTGCCGTCAATCCTGCGATAGCAATACCAATAAAAAGTACAGT
+CCACGAAGGATAAACATTTTCAAGTGAAAAATCTTTTAAATATTTTATTGAAAAAATAAT
+CATATGCGTCATAATTCCCACAAGGCATAAAATCCAAATAGGCGTTATTAAGCTATTGAT
+AAAAGTTATGTTACTAAAAAATGTATTTAAATAAGTAGTACCTAAAAAGCCAGACATGAA
+AAATGTTGTGAACACTGATGAAACTAGAGGACTGTTTAATTGTTCTTTCACATTATTAAA
+ATATTTGATCATAGTACATAAAAGGTGAATCCAAATCAAGAAAGCAAAGATTCCGCAAAC
+AGCGTTTAAAGTAAGAGATAAGTCTTTTAATAGATTACCCAGGCCTAATAATCCTAAGAC
+TAGTCCTGACGTTACTAGAGGTGCTTTTTGAAGTCTCATGATTTACAACCTTTCTTATGT
+GATTTTCTTCACTAATTATATCATGATAGCTATGGCCAATTAATAAGAAGAGTGTGTACT
+ATTACGTTATTAGAGTATGTATATTGGATTGATAGACACATAATTGACATTTAAATCTCA
+AAATTAATGATATTTGAGGTATGCTTTGCAACCTAAATATTGGAATATGTGGAAAAGTAA
+TTATTTAATTTAAATGATGATTGAAGATTTACAAGGGGGTGTACAAAATGAGAAATCAAA
+TTCAAAAACTATTAGACAGTGATTTGAGCAGTTTACATATATCGAAACAAACAGGAGTTC
+CACAAAGCACAATACACAGAATGAGAAAAAAAGAAAGATCATTAGACAATATGTCATTGA
+AAAACGCTGAACTACTTTATAAATTTGCCAATAGTATATTTAGCAATGAAAATTAAGAAG
+AATAATTAGTGAGTTAAATAATTAAAAAACCACGTCTCGATGGACGTGGTTATTTTTTTA
+AATGTATTTAATTATAGGATTTCGGGCCCCTGAAAAGTCCCTAAAATTTTGAATAGTATC
+AAAATCTATAGGAATAATATAATAATAAAAATCTCTACGCATGCAAATGGTGAGTGTTAA
+AAATCTTGGTGTAGTGTTGGTGTAGTTCAGGTGCAGTATAGATGAAATTTGAGCACAAAA
+TTACTTAATTAAAAATGTATAAACAAGTGTCAGACGCGTGTCAATTGTGTGTCAAAAAAT
+TCTATGACGAATAAGCATGCTTGTTTTAATTACTGTATTTTCGGGGCTTATGCGGGGGAC
+GTTTTGGTGACGCATCATACTATATTACTGAAATTCAAAACAAAAAGAGCCCCGTAATCA
+CGGAACTCTTTTGTTTGGTAATGCGTATAAAAATACCTATAAACGTCCTGGGAGGGATTC
+GAACCCCCGACCGATGGCTTAGAAGGCCATTGCTCTATCCAGCTGAGCTACCAGGACACG
+TTTAACAACACAAGAATTATTATATCTAAATGAACTTAAATTAGCAATACCTTGTAAATA
+AAAAATGTTTATATTTTTCACTATTATAGAGCTATTTATCTAAAAAGGTTCAATAAGACT
+TAAATGCGAATTCAGGCAACTTAATTGTGTTAAATACAGTTTTGAATGCCTAACTGTATT
+TCTTTTCTCTTTAAAATACAGTTAAGTACATTATAAGATGTTGTGCGGATAAACAAACTA
+ATTGCATCAAATTTATTTTAAAATAACAACAACAAAACGTTAAGCGAATAACATTTCGGT
+GATTTAAAAGCTACGCACGTTTTTGTTATCTTCAAATTTAAATTTTAAGGAGTGTTTTCA
+ATGGAAGGTTTATTTAACGCAATTAAAGATACCGTAACTGCAGCAATTAATAATGATGGC
+GCAAAATTAGGCACAAGCATTGTGAGCATCGTTGAAAATGGCGTAGGTTTATTAGGTAAA
+TTATTCGGATTCTAATTTCAATATGTTATGTAAGTAATCAGTATTATTTCAAAGGTGAGG
+GAGAGATTTAAATGACTGGACTAGCAGAAGCAATCGCAAATACTGTGCAAGCTGCACAAC
+AACATGATAGTGTGAAATTAGGCACAAGTATCGTAGACATCGTTGCTAACGGTGTGGGTT
+TACTAGGTAAATTATTTGGATTCTAATATAATAACTAATATTCTTTAAAATAAACTGGGT
+GAGCATACTTTAATGTTATGCACTCAGTTTATTTTATTTGCAGAAATTTGAGCCTCTGTT
\ No newline at end of file
diff --git a/t/data/reformat_input_gffs/query_3.gff b/t/data/reformat_input_gffs/query_3.gff
new file mode 100644
index 0000000..c8a0672
--- /dev/null
+++ b/t/data/reformat_input_gffs/query_3.gff
@@ -0,0 +1,220 @@
+##gff-version 3
+##sequence-region abc|SC|contig000001 1 15000
+abc|SC|contig000001 Prodigal:2.60 CDS 172 1131 . - 0 ID=1_1;gene=different;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:Q2G1X0,protein motif:TIGRFAMs:TIGR01002,protein motif:Pfam:PF07968.6;locus_tag=abc_00001;product=Alpha-toxin,beta-channel forming cytolysin,Leukocidin/Hemolysin toxin family protein;protein_id=gnl|SC|abc_00001
+abc|SC|contig000001 Prodigal:2.60 CDS 1804 1950 . + 0 ID=abc_00002;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00002;product=hypothetical protein;protein_id=gnl|SC|abc_00002
+abc|SC|contig000001 Prodigal:2.60 CDS 1934 2131 . + 0 ID=abc_00003;inference=ab initio prediction:Prodigal:2.60;locus_tag=abc_00003;product=hypothetical protein;protein_id=gnl|SC|abc_00003
+abc|SC|contig000001 Prodigal:2.60 CDS 2621 3337 . - 0 ID=abc_00004;inference=ab initio prediction:Prodigal:2.60,protein motif:CLUSTERS:PRK13350,protein motif:Pfam:PF02876.11;locus_tag=abc_00004;product=superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00004
+abc|SC|contig000001 Prodigal:2.60 CDS 3445 4170 . - 0 ID=1_2;gene=speH;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:UniProtKB:P0C0I6,protein motif:CLUSTERS:PRK13349,protein motif:Pfam:PF02876.11;locus_tag=abc_00005;note=SPE H;product=hypothetical protein,superantigen-like protein,Staphylococcal/Streptococcal toxin%2C beta-grasp domain;protein_id=gnl|SC|abc_00005
+##FASTA
+>abc|SC|contig000001
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
+ATACCCACCACATTTGGTGGAGAACCAAAAATTAGCCGAAAAACATCATTTCTGAAGTTA
+TCGGCTAAAGTTATAAATTATATTTATTTGTACATGAACAAATAATTTACATTAATTTGT
+CATTTCTTCTTTTTCCCAATCGATTTTATATCTTTCTGAAGAACGATCTGTCCATTTATC
+TTTAGTATTGGTACCTTTCCAATTTGTTGAAGTCCAATGCAATTGGTAGTCATCACGAAC
+TCGTTCGTATATTACATCTATATTTGTTTGTTGTTTGGATGCTTTTCTATCCATAGTAAT
+AACTGTAGCGAAGTCTGGTGAAAACCCTGAAGATAATAGAGAACTTGCTTTGTTAGGATC
+AAGGAAGTTCTCTGCTGCTTTCATAGAACCATTTCTAGTTTTCATGAAAAGTTGATTGCC
+ATATACCGGGTTCCAAGAATCTCTATCATATGGTCCCCAATTTTGATTCACCATATTGTT
+AAATATCACTTTCCAGCCTACTTTTTTATCAGTTGGGCTCTCTAAAATTGTTTTGAAATC
+AGGTTGAACATATTTCAGTGTATGACCAATCGAAACATTTGCACCAATAAGGCCGCCAAT
+TTTTCCTGTATCATCACCAGTAACATTACCGTTGAATCCATAAGTTAAAGTACTCATATA
+CTCTTTTGTATCAATCGAATTTCTTGGATAGTAATCAGATATTTGAGCTACTTCATTATC
+AGGTAGTTGCAACTGTACCTTAAAGGCTGAAGGCCAGGCTAAACCACTTTTGTTAGCACC
+TTCTTCGCTATAAACTCTATATTGACCAGCAATGGTACCTTTCGTTCTAATAACTAGCAG
+TTTTTTATTGTGATTTTTATCATCGATAAAACTATAAAATACTTTTTTGTGCATGCCATT
+TTCTTTATCATAAGTGACTAAATCACCTGTTTTTACTGTAGTATTGCTTCCAATATCTGT
+AGTACCGGTTTTAATATTAATATCAGAATCTGCGGCATTAGCGACAGGATTCATTAATAT
+GGAACCTAGCAATAGTGTTGTTGTTACTGAGCTGACTATACGTGTTTTCATTTTCATCAT
+CCTTCTATTTTTTTTAACGATTTGAGGAAACAATAATCAATATGTCAATTTAGAATATTG
+CAGTTGAGACATATCAAATATTTATAATCGTTTATATTAGTATATTTAATGTAGCAACTG
+ATAAATTACTGAGTGATGATGAGTGATTATTTTAAGAATATGTTTTTAACTTTTATTTAA
+AATTTGAAAGGAAGCATTTCAATTTCGAGGGTTAGTCAAAGTTGAATAAATTCTTTATGA
+AACAAGGAAAAGACATAGCTAATTTTATTGATTAATTTCTTTAAAACTAATGATTTGTTT
+GATTTAAAAATGTAATCGATTACAATATAAAAATACAAATATCTTAGAATTAAATCAATT
+AATTAACTATTAAATAAAAATTAAATATATATTAACTACTGTAAATTAATAAATAGAAAT
+AGAGAAAAAGGGTATTAATTATGTTTGGAATTTCGTCGGGAATAATTTTTGCCATTACAT
+AGAAATATCTAATAGATAATGAAAAAGTATCGTATGTATTTTTAATATAGTGTAAAATAT
+CATATGTAAAATAAAATGTAGATTTTTAGTTAGAGGCATTATAAGAAAATTTTGAGTATA
+GGTTAGCTTTTAATTATGAATCTTATTGAAATTTGATTAATAAATATATGATAGGGGATT
+AAAATGAAACTATTTTATATCGTATTTCTTATTATTATATGGCTGAATATATTTTTAGGA
+AATGAAATTATCCATACACTGACTGTTTTAATAACAACATTGTATATTGTTAATTCAAGA
+AAGGGGATTAAAAATGACAGAGTTGAATAATATTATAAACTCTCTTCAATCTTTGTTTGA
+GTCTGAATCAGGCTATAAAATTTCGAAAAATTCAGGAGTTCCATATCAAACAGTACAAGA
+TTTAAGAAATGGGAAAACCAAACTAGAAGATGCTAGATTTAGAACGATTATTAAACTTTA
+TAGTTACTATGTCTCATTAAAAGAACATTAATCATGGGACAATAAAGTATTGCTATAATA
+ATTGAATCATTAAATGAAGGAATAGAGCCTAAGACATAATAAATCAATGTCTTAGGCTCT
+ACAATATTATATTGGTAGTAGTTGACCGAATGAAAATGACCATGTAACAAGCATTTTTGG
+GGCCCCAACACAGAAGCTGACGAAAAGTCAGCTTACAATAATGTGCAAGTTGGGGATGGG
+CCCCAACACAGAGAATTTCAAAAAGAAATTCTACAGACAATGCAAGTTGGCGGGGCCCCA
+ACATAGAGAAATTCAAAAAGAAATTCTACAGACAATGCAAGTTGGGGAGTGACAACGAAA
+TAAATTTTATAAAATACCATTTCTGTCACATTCCTACTCCCAATTCCATTTAAATATATA
+GAAAATTTCACCTATTATATACATCATACACTTTAAAAATTATCATTTAAATAATCTGAT
+TTGGAATTAAAGTGCATGAAGTATAAGTCACCTTCATATACTAATCAAAGAGGACGTCAA
+CAGTTATTTTATTAGGATTTTTAACATAAACATTTGCTAGATCTGAATGTAATCTTTTGC
+TTAAATCAATAGTGTAGTTATTACCGCCACCGGTGATCTTAAGCTTACCTTTATTACGAT
+TTTCGGTATATAATATTTTATTTTTTATTAACGCTTCTCGTGCACGGAAATCGATTTCTT
+TCAATGTTAATACTGGTTTATTGCCTTGGTATATTTTATGCGCACCAATAATCGTTTGTA
+GTTTATCTTTGTATTGCACAAAAAGATTATAAGTTTTATCAGAAGGTTTTGCGGCTGGTG
+TAACGCCACCTGTAAATGTCTCTCTATAAGACCACCATAACTGATCAGTATCTTTGTCTT
+TTAGTCCAAACACATCTACGTAACGATCTTTTAACTGATTAATATTTCCCCAACTTTCAG
+CGCCCCATAAAGATATATGTGCTGACCATGAATATCTCTTAAGTTCAACATAAATGTTTC
+CATTATCATATTGATATAGCCATTTATTTGAAAATGAAAAATGAGGCTGTGTGTAATATT
+TAATTAATTCATTGATGTTAGTTTCATCTTGACCAATGCTATAAGCTTTAGCTTCAGAGT
+AAAAACTAAATACTGGTTTTTGATTTTGAGGTAATACAGTACCTAATAGTAATAATGTTG
+TCGTTAAAATTATATTTTTCGTGATGTTCTTACTCATTAGAACATCTCCTTTCAGAGGAA
+TCATGATACGAGGAATAAGAAATTTAAATGTGAGCGAAGTCAATATAGTATTTGCGATTA
+TTTTTATTAACTCCATTATTATTGTTAGTTTGATTTTTCGAGGATAACTTCAATTTTTGC
+ATTTTGAGGTTTTTTAACATATCTATTTGCATCAGTTGATGGCAACCTTTTACTTAAATC
+TATTGTGTAGTTATTGTCTGTACCTGTTATTTTAATTTGTCCTTTATTATAAGAATTATT
+ATATAATTTTTTACTTTTAATTAATGTTTGACGAATACGAAAATCTAATTCTTTTAAAGT
+TAAAACAGGCTTATTGCCTTCATAAACTGGAAATCCGCCAGTAAACGTTTCTGCTTTATC
+TTTATATGTTACATTCAGTTTATAGTGTTTATCGTTAGATGTTGCTGCAGGAGTAACACC
+ACCAGTAAACGTTTCTTGAGATAATGCAAAAGAATCAATGGTTTCTTGGTCTTTTATGCC
+AAAAATATCAACGCTTTTATTTCTTAATTGGTTGATATTGCCCCAACTTTCAGGTCCATA
+AACTTGAATATGACTATACCAAGAAAACTGTAACAACGTTGCATGAATCGTACCGTTATC
+TTTTTGCCATAACGTACTGTTAGAGAAGGTTAAATATTTTTGCGAGTAATATTTAGTTAA
+CTCATTAACGTTAGTTTCGTTTTGATTTATATAATAAGCTTTCGCTTCAGATGAAGAATT
+GATAGGTGTATTAGGAAATTGTGTAAATGCTGTACCTAATAGTAACAATGTTGTTGATAA
+AATAATTTTTTTCGTGATGTTATTGTTCATTCGAATTTCTCCTTTGAGTATTGTTGGAAT
+GTTTAATTATAAAAAGGGGTTAATTAGATAATTGAAATTATCCGCATTTACAAAAGGTAA
+TAGGTTAGTTAGATTTTTCGAGTATGACTTCAATTTGTGCATTTTTAGGATTTTTAACAT
+AACGGTTTGTGTCAGTTAATTTTAACTTTTTACTTAAATCAATCGTGTAATTATTTCCAT
+CAGCAGTTATCTTAATTTGACCTTTATTAAATTCTCCGTTATATAACTTTTTATTCTTTA
+TTAATGTTTGACGAATACGGAAATCTAATTCTTTTAAAGTTAATACTGGTTTATTTCCTT
+TGTAAAATTCATGTCCACCGATGATAGTTTGTTGTTTATCACTATATTTTAAAAATAGTC
+TATAAGGTTTATCAGATGAAGTAGCTGCTGGCGTAACACCACCAGTAAATGTTTCATCAT
+AAGTCCAGTAACCTTCAACTGTGTCCTCATCTTTAGTTCCAAATATATCAACGTATTTAT
+TTCTTAACTGATTAATGTTTCCCCAACTCTCGGATCCAAACACTTGAATATGACTATACC
+AAACCCACGTTTGCAATGTTGCATGAATGCTACCATTGGGCTTTTGCCATAGCCATTTTC
+CAGATAATGAAAAATGCGGCTGAGTGTAATATTTGATTAACTCATTGATATTAGTCTCGT
+TTTCACTGATATTATAGGCTTTTGCTTCAGATGAAAAACTGATTGGTGTTTTAGGAAGTT
+GTGTTGATGTGGTTCCTAAAAGTAACAATGCTGTTGATAAAACTAATTTATTCATGATGT
+TCTTTTTCATATGAAAATCTCCTTTGCGTGAATTACCCAAAGTATATAAGCTATTACACC
+GATTCGGAATTAAATAAAAGCTAAAACTATGTTAAATAAACTTAAACAGTTAGTAGTGTT
+ATTTAAGCAAAACTTATCATTTTTAAGTTTTGGACAGAAACAGTACTTAATAAAGTAGGC
+GGGAGTTATATATTAAAAACGACACGTTACAATTATTCTCTAATCAATTGCATTAAATTG
+TTTGATAATTGAATTTTCTAACTACTTGAAAAATAGTTATACTTTAAATGTAGTACTTAT
+TTTAATTATTTCCTACTACTTAAATTTAATATTAATAAAATGTTCATTTAATTATTGATA
+AAATATTACAAATTTTAATAGTAGGTTGTGTTTATTTTGTATGCGCTTACAATTTAGGTG
+TAACTAAAATAAAAGGAGTTGTTATTAATGAAAAATTTACGAAACAGAAGTTTTTTAACT
+TTATTAGACTTTTCACGACAAGAGGTAGAATTCTTATTAACACTCTCCGAGGATTTAAAA
+CGTGCTAAATATATTGGCACTGAAAAGCCTATGTTAAAAAATAAAAATATTGCACTGTTA
+TTTGAAAAAGATTCTACAAGAACGCGATGTGCATTTGAAGTTGCAGCGCATGATCAAGGT
+GCAAATGTAACTTATTTAGGCCCAACTGGATCACAAATGGGTAAAAAAGAAACAACTAAA
+GATACTGCACGTGTGCTTGGTGGAATGTATGATGGCATTGAATACCGTGGTTTTTCACAA
+AGAACAGTAGAAACTTTAGCTGAAAATTCAGGCGTACCAGTGTGGAATGGTTTAACTGAT
+GAAGATCATCCTACTCAAGTTCTTGCTGATTTCTTAACAGCAAAAGAAGTCTTAAAAAAA
+GATTATGCAGATATTAACTTTACATATGTTGGAGATGGTCGTAATAACGTTGCAAATGCA
+TTAATGCAAGGTGCTGCCATTATGGGTATGAACTTCCATTTAGTTTGTCCAAAAGAATTA
+AATCCAACAGATGAATTATTAAATCGCTGTAAAAATATTGCCGCTGAAAATGGTGGCAAC
+ATATTAATCACAGATGATATTGACCAAGGTGTAAAAGGTTCGGATGTAATTTACACTGAT
+GTTTGGGTATCAATGGGTGAACCTGATGAAGTATGGAAAGAACGACTTGAATTATTGAAA
+CCATATCAAGTAAATAAAGAAATGATGGATAAAACTGGTAATCCAAATGTTATTTTTGAG
+CATTGCTTACCATCTTTCCATAATGCTGATACGAAAATTGGTCAACAAATTTTTGAAAAA
+TATGGTATTCGAGAAATGGAAGTTACAGATGAAGTATTCGAAAGTAAAGCTTCAGTTGTA
+TTCCAAGAAGCTGAGAACAGAATGCATACAATCAAAGCAGTCATGGTTGCTACATTGGGT
+GAATTTTAAATGATATAAGGAAGTGAATATGATGGCGAAAATAGTAGTAGCATTAGGTGG
+TAATGCTTTAGGAAAATCACCTCAAGAACAACTCGAGCTTGTTAAAAATACTGCGAAATC
+ATTAGTAGGATTAATAACAAAAGGACATGAGATTGTTATTAGTCATGGTAATGGACCACA
+GGTTGGAAGCATTAATTTGGGACTTAACTATGCTGCAGAACATAACCAAGGTCCGGCATT
+TCCATTTGCTGAATGTGGCGCAATGAGTCAAGCTTACATCGGCTATCAATTACAAGAAAG
+CTTACAAAATGAATTGCATTCTATTGGAATGGATAAACAAGTGGTAACACTAGTGACACA
+AGTTGAAGTTGATGAAAATGATCCGGCATTTAACAATCCTTCAAAACCAATTGGGTTATT
+TTACAACAAAGAAGAAGCTGAACAAATTCAAAAAGAAAAAGGATTTATATTTGTTGAAGA
+TGCTGGAAGAGGATATAGACGCGTTGTTCCTTCACCACAACCCATCTCTATTATTGAATT
+AGAGAGTATTAAAACACTTATTAAAAATGATACACTCGTTATTGCTGCTGGTGGTGGAGG
+TATACCAGTAATTAGAGAGCAACATGATGGTTTTAAAGGTATTGATGCAGTTATAGACAA
+AGATAAAACAAGTGCGTTGTTGGGTGCTAATATTCAATGCGATCAATTGATTATTTTAAC
+AGCAATTGATTATGTATATATTAATTTTAACACTGAAAACCAACAGCCTTTGAAAACAAC
+AAATGTTGATGAATTAAAACGATATATAGACGAAAATCAATTTGCAAAAGGAAGTATGTT
+ACCAAAAATTGAAGCAGCCATATCATTTATTGAAAACAATCCAAAAGGAAGTGTGCTTAT
+AACATCATTAAATGAATTAGATGCTGCCTTAGAGGGTAAAGTAGGTACTGTGATTAAAAA
+GTAATTGAATTGAAACGCTTTTCAATTACTATATGTCAAATGCATGATTTTTATTATTTA
+TGTGCACCCCCTGAAAATAATGCCTCTATTTTGATGCGGGGTGCACTTTCTTAATTTATA
+TTTATAAAATCTTTAAGGTAGAAATGCTAGGTTAAATGTCGAAGGAGATGAAACCGTGGA
+AAATACAATTAATGAAAGTGAAAAGAAAAAACGATTTAAATTAAAAATGCCAGGTGCATT
+TATGATTTTATTCATTTTAACGGTTGTTGCAGTTATAGCAACATGGGTTATTCCTGCTGG
+TGCATATTCTAAACTTTCTTACGAACCTTCATCCCAAGAACTAAAGATAGTTAACCCTCA
+TAACCAAGTGAAAAAGGTTCCGGGTACGCAACAGGAACTAGACAAAATGGGGGTTAAAAT
+TAAGATTGAACAATTTAAATCAGGTGCAATTAATAAGCCAGTATCAATTCCGAATACTTA
+TGAAAGATTAAAGCAACATCCAGCTGGACCAGAACAAATAACAAGTAGCATGGTTGAAGG
+TACGATAGAAGCGGTCGATATCATGGTATTCATTCTTGTACTAGGGGGACTTATTGGCGT
+AGTTCAAGCCAGTGGTTCTTTTGAATCGGGATTGTTAGCTTTAACGAAGAAAACAAAAGG
+GCATGAATTTATGCTAATTGTGTTTGTATCAATACTAATGATTATCGGCGGGACGTTATG
+TGGTATTGAAGAAGAAGCTGTAGCATTCTATCCGATTTTAGTCCCTATATTTATAGCGTT
+AGGATACGATTCTATCGTTTCAGTTGGTGCCATATTCCTTGCCAGCTCTGTCGGTAGTAC
+ATTTTCAACTATTAACCCGTTCTCGGTTGTAATTGCCTCTAATGCCGCTGGTACAACTTT
+TACGGATGGCTTGTATTGGAGAATAGGTGCTTGTATTGTCGGTGCGATTTTTGTTATTAG
+TTATTTATATTGGTACTGTAAAAAAATTAAAAACGATCCTAAAGCGTCATATTCTTATGA
+AGACAAAGATGCTTTTGAACAGCAATGGTCTGTATTAAAAGATGACGATAGTGCCCATTT
+TACTTTGCGTAAGAAGATAATCCTTACATTATTTGTACTACCATTTCCAATTATGGTATG
+GGGAGTTATGACGCAAGGTTGGTGGTTCCCAGTTATGGCTTCAGCATTTTTAATATTTAC
+AATTATAATAATGTTTATTGCTGGGACAGGTAAATCTGGATTGGGAGAAAAAGGAACTGT
+AGATGCATTTGTCAATGGTGCATCAAGTTTAGTAGGTGTATCTTTAATTATTGGTTTAGC
+TCGAGGTATTAATTTAGTGTTGAATGAAGGTATGATTTCAGATACAATCTTACACTTTTC
+ATCATCTTTAGTTCAACATATGAGTGGACCATTATTTATCATCGTATTACTATTTATTTT
+CTTCTGTTTAGGTTTTATCGTGCCATCATCTTCTGGATTAGCGGTATTATCAATGCCTAT
+CTTTGCACCACTAGCTGATACAGTAGGTATACCAAGATTCGTCATCGTTACGACATATCA
+ATTTGGTCAATATGCGATGTTATTCTTAGCGCCGACTGGACTTGTTATGGCCACACTACA
+AATGTTAAACATGCGATATTCACATTGGTTCCGATTTGTATGGCCGGTAGTTGCTTTTGT
+ATTGATTTTCGGTGGCGGAGTACTAATTACGCAAGTACTAATTTATTCATAATTTGAAAT
+GCTATATTATAAAAATACTAATTGGGTTTTATGCATCTCGTAGGTTTGTAGAAATACTAA
+ACTAAGCGAGGTGCATTATTATTTTTGATTAAGAAAATAATGACGGTAATGATAACACTA
+GTAAGTAATTGATACAATGCTCTATTTAATAATGATATTTTTAAAATTTGTTTTTAATGT
+AATGTTAGATCTATGGTATATTATATTTATCGTGGTAAATATGTATTTGCTGTAAACAGT
+TTTTGTAACACATGACACATATGGTTGTGAAAATAGCATATATAAAGGATGGCTATAAAT
+GACACATTTGACAAAGGTTTTAGATACACTAACTGGAATATGCGTAGTATTATTATTTAG
+TAAATATTTTGTGGCGTATGCAAATATGGTGTTTGATTGGAATTTAAGATGGTATTTGCT
+AGAAAACATACCACATTTGCCAATTATATTATTTATTCTGATGTTTATTTTCGGAGTACC
+TTCTGAAATGATAAAAGATAGGCAAAGGAAAAATAACGGTGTTTAATTTATCGATATTTA
+GAGGTGATAAAATTTGTCAACTATTACAAAGACTAAAATAAAAATCTTTATTAATTATTT
+TATTGGTATATTAGCCTTGGCGTTTGCTGCTTATATATTATTTAAATAAAGGTTAGAGTG
+AAACGTGTTTATGAACTAGACGTTCTAGTATAGTTACTACAGCTTTAGTCAGAAGGTATC
+ATTGATAAGATCATATTAAATCAAAGAGGCATTGATATACACTAAAAAGAGGCAAGATTA
+CCTGCCTCTTTTTTAGTTATTAAATATGCGTGTTAATTCTTGGTAATAGTGTTACTGAGA
+CGCATTACGAAGAAATTTATCTTGATTTTCCTTTTTTAAAAAGAAGTGAAGATATCCTAT
+AAAGACTCTAAGTACTATTACAGTGGCTAATAACACTTCGATAAACAAAAGACCTTTCCA
+AATATCTGGAAACATAAGTACAGGCAAACTGTTCTTTAAAGCAGTTGCTGAGATTACTAA
+AGGGAATGTGAAAGCTGAAAATACGGGCGAAAAAGGTTCTTTTAGTAATTTAGGCAATTG
+TATAATGATATAAAAATAAAATATTTGAGCTAATATTAAAAATATAATTACGATAAAAGC
+ATTCGCCTTAGGAAAGGCTATAACATATGCTGCAGCGACTAAAGAAAATGGTGCACAAAT
+TGTCGATGTGTTCGGTTTGATTGACGTCTGCAATGGAAATGCTTTTAATCGCTTGAAAAC
+AATAGGTAAGACAATACAAGTAGCTACAAAGCCATATATTACTGTTAATTGACCTATGAA
+AAAACATCCGCTAACGGGTGCCGTCAATCCTGCGATAGCAATACCAATAAAAAGTACAGT
+CCACGAAGGATAAACATTTTCAAGTGAAAAATCTTTTAAATATTTTATTGAAAAAATAAT
+CATATGCGTCATAATTCCCACAAGGCATAAAATCCAAATAGGCGTTATTAAGCTATTGAT
+AAAAGTTATGTTACTAAAAAATGTATTTAAATAAGTAGTACCTAAAAAGCCAGACATGAA
+AAATGTTGTGAACACTGATGAAACTAGAGGACTGTTTAATTGTTCTTTCACATTATTAAA
+ATATTTGATCATAGTACATAAAAGGTGAATCCAAATCAAGAAAGCAAAGATTCCGCAAAC
+AGCGTTTAAAGTAAGAGATAAGTCTTTTAATAGATTACCCAGGCCTAATAATCCTAAGAC
+TAGTCCTGACGTTACTAGAGGTGCTTTTTGAAGTCTCATGATTTACAACCTTTCTTATGT
+GATTTTCTTCACTAATTATATCATGATAGCTATGGCCAATTAATAAGAAGAGTGTGTACT
+ATTACGTTATTAGAGTATGTATATTGGATTGATAGACACATAATTGACATTTAAATCTCA
+AAATTAATGATATTTGAGGTATGCTTTGCAACCTAAATATTGGAATATGTGGAAAAGTAA
+TTATTTAATTTAAATGATGATTGAAGATTTACAAGGGGGTGTACAAAATGAGAAATCAAA
+TTCAAAAACTATTAGACAGTGATTTGAGCAGTTTACATATATCGAAACAAACAGGAGTTC
+CACAAAGCACAATACACAGAATGAGAAAAAAAGAAAGATCATTAGACAATATGTCATTGA
+AAAACGCTGAACTACTTTATAAATTTGCCAATAGTATATTTAGCAATGAAAATTAAGAAG
+AATAATTAGTGAGTTAAATAATTAAAAAACCACGTCTCGATGGACGTGGTTATTTTTTTA
+AATGTATTTAATTATAGGATTTCGGGCCCCTGAAAAGTCCCTAAAATTTTGAATAGTATC
+AAAATCTATAGGAATAATATAATAATAAAAATCTCTACGCATGCAAATGGTGAGTGTTAA
+AAATCTTGGTGTAGTGTTGGTGTAGTTCAGGTGCAGTATAGATGAAATTTGAGCACAAAA
+TTACTTAATTAAAAATGTATAAACAAGTGTCAGACGCGTGTCAATTGTGTGTCAAAAAAT
+TCTATGACGAATAAGCATGCTTGTTTTAATTACTGTATTTTCGGGGCTTATGCGGGGGAC
+GTTTTGGTGACGCATCATACTATATTACTGAAATTCAAAACAAAAAGAGCCCCGTAATCA
+CGGAACTCTTTTGTTTGGTAATGCGTATAAAAATACCTATAAACGTCCTGGGAGGGATTC
+GAACCCCCGACCGATGGCTTAGAAGGCCATTGCTCTATCCAGCTGAGCTACCAGGACACG
+TTTAACAACACAAGAATTATTATATCTAAATGAACTTAAATTAGCAATACCTTGTAAATA
+AAAAATGTTTATATTTTTCACTATTATAGAGCTATTTATCTAAAAAGGTTCAATAAGACT
+TAAATGCGAATTCAGGCAACTTAATTGTGTTAAATACAGTTTTGAATGCCTAACTGTATT
+TCTTTTCTCTTTAAAATACAGTTAAGTACATTATAAGATGTTGTGCGGATAAACAAACTA
+ATTGCATCAAATTTATTTTAAAATAACAACAACAAAACGTTAAGCGAATAACATTTCGGT
+GATTTAAAAGCTACGCACGTTTTTGTTATCTTCAAATTTAAATTTTAAGGAGTGTTTTCA
+ATGGAAGGTTTATTTAACGCAATTAAAGATACCGTAACTGCAGCAATTAATAATGATGGC
+GCAAAATTAGGCACAAGCATTGTGAGCATCGTTGAAAATGGCGTAGGTTTATTAGGTAAA
+TTATTCGGATTCTAATTTCAATATGTTATGTAAGTAATCAGTATTATTTCAAAGGTGAGG
+GAGAGATTTAAATGACTGGACTAGCAGAAGCAATCGCAAATACTGTGCAAGCTGCACAAC
+AACATGATAGTGTGAAATTAGGCACAAGTATCGTAGACATCGTTGCTAACGGTGTGGGTT
+TACTAGGTAAATTATTTGGATTCTAATATAATAACTAATATTCTTTAAAATAAACTGGGT
+GAGCATACTTTAATGTTATGCACTCAGTTTATTTTATTTGCAGAAATTTGAGCCTCTGTT
\ No newline at end of file
diff --git a/t/data/reformat_input_gffs/real_1.gff b/t/data/reformat_input_gffs/real_1.gff
new file mode 100644
index 0000000..3242220
--- /dev/null
+++ b/t/data/reformat_input_gffs/real_1.gff
@@ -0,0 +1,223 @@
+##gff-version 3
+##sequence-region 2 1 15000
+2 annotation remark 1 15000 . . . accessions=REL607;comment=Source DNAEscherichia
+2 feature source 1 4629812 . + . mol_type=genomic DNA;organism=Escherichia coli;strain=REL607
+2 feature CDS 190 255 . + 0 codon_start=1;gene=thrL;locus_tag=ABC_00001;note=b0001;product=thr operon leader peptide;protein_id=kribb:ABC_00001;transl_table=11;translation=MKRISTTITTTITITTGNGAG
+2 feature gene 190 255 . + . gene=thrL;locus_tag=ABC_00001
+2 feature CDS 336 2798 . + 0 EC_number=2.7.2.4,1.1.1.3;codon_start=1;gene=thrA;locus_tag=ABC_00002;note=b0002;product=bifunctional aspartokinase I/homeserine dehydrogenase I;protein_id=kribb:ABC_00002;transl_table=11;translation=MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTISGQDALPNISDAERIFAELLTGLAAAQPGFPLAQLKTFVDQEFAQIKHVLHGISLLGQCPDSINAALICRGEKMSIAIMAGVLEARGHNVTVIDPVEKLLAVGHYLESTVDIAESTRRIAASRIPADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQVPDARLLKSMSYQEAMELSYFGAK [...]
+2 feature gene 336 2798 . + . gene=thrA
+2 feature CDS 2800 3732 . + 0 EC_number=2.7.1.39;codon_start=1;gene=thrB;locus_tag=ABC_00003;note=b0003;product=homoserine kinase;protein_id=kribb:ABC_00003;transl_table=11;translation=MVKVYAPASSANMSVGFDVLGAAVTPVDGALLGDVVTVEAAETFSLNNLGRFADKLPSEPRENIVYQCWERFCQELGKQIPVAMTLEKNMPIGSGLGSSACSVVAALMAMNEHCGKPLNDTRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENDIISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQPELAAKLMKDVIAEPYRERLLPGFRQARQAVAEIGAVASGISGSGPTLFALCDKPDTAQRVADWLGKNYLQNQEGFVHICRLDTAGARVLEN
+2 feature gene 2800 3732 . + . gene=thrB;locus_tag=ABC_00003
+##FASTA
+>2
+ACTGGCCGCCTAATAATAAAAACTCTAAAAGTTGTAATTTAAAATAGTTCTTTAAATTAT
+ATACCCACCACATTTGGTGGAGAACCAAAAATTAGCCGAAAAACATCATTTCTGAAGTTA
+TCGGCTAAAGTTATAAATTATATTTATTTGTACATGAACAAATAATTTACATTAATTTGT
+CATTTCTTCTTTTTCCCAATCGATTTTATATCTTTCTGAAGAACGATCTGTCCATTTATC
+TTTAGTATTGGTACCTTTCCAATTTGTTGAAGTCCAATGCAATTGGTAGTCATCACGAAC
+TCGTTCGTATATTACATCTATATTTGTTTGTTGTTTGGATGCTTTTCTATCCATAGTAAT
+AACTGTAGCGAAGTCTGGTGAAAACCCTGAAGATAATAGAGAACTTGCTTTGTTAGGATC
+AAGGAAGTTCTCTGCTGCTTTCATAGAACCATTTCTAGTTTTCATGAAAAGTTGATTGCC
+ATATACCGGGTTCCAAGAATCTCTATCATATGGTCCCCAATTTTGATTCACCATATTGTT
+AAATATCACTTTCCAGCCTACTTTTTTATCAGTTGGGCTCTCTAAAATTGTTTTGAAATC
+AGGTTGAACATATTTCAGTGTATGACCAATCGAAACATTTGCACCAATAAGGCCGCCAAT
+TTTTCCTGTATCATCACCAGTAACATTACCGTTGAATCCATAAGTTAAAGTACTCATATA
+CTCTTTTGTATCAATCGAATTTCTTGGATAGTAATCAGATATTTGAGCTACTTCATTATC
+AGGTAGTTGCAACTGTACCTTAAAGGCTGAAGGCCAGGCTAAACCACTTTTGTTAGCACC
+TTCTTCGCTATAAACTCTATATTGACCAGCAATGGTACCTTTCGTTCTAATAACTAGCAG
+TTTTTTATTGTGATTTTTATCATCGATAAAACTATAAAATACTTTTTTGTGCATGCCATT
+TTCTTTATCATAAGTGACTAAATCACCTGTTTTTACTGTAGTATTGCTTCCAATATCTGT
+AGTACCGGTTTTAATATTAATATCAGAATCTGCGGCATTAGCGACAGGATTCATTAATAT
+GGAACCTAGCAATAGTGTTGTTGTTACTGAGCTGACTATACGTGTTTTCATTTTCATCAT
+CCTTCTATTTTTTTTAACGATTTGAGGAAACAATAATCAATATGTCAATTTAGAATATTG
+CAGTTGAGACATATCAAATATTTATAATCGTTTATATTAGTATATTTAATGTAGCAACTG
+ATAAATTACTGAGTGATGATGAGTGATTATTTTAAGAATATGTTTTTAACTTTTATTTAA
+AATTTGAAAGGAAGCATTTCAATTTCGAGGGTTAGTCAAAGTTGAATAAATTCTTTATGA
+AACAAGGAAAAGACATAGCTAATTTTATTGATTAATTTCTTTAAAACTAATGATTTGTTT
+GATTTAAAAATGTAATCGATTACAATATAAAAATACAAATATCTTAGAATTAAATCAATT
+AATTAACTATTAAATAAAAATTAAATATATATTAACTACTGTAAATTAATAAATAGAAAT
+AGAGAAAAAGGGTATTAATTATGTTTGGAATTTCGTCGGGAATAATTTTTGCCATTACAT
+AGAAATATCTAATAGATAATGAAAAAGTATCGTATGTATTTTTAATATAGTGTAAAATAT
+CATATGTAAAATAAAATGTAGATTTTTAGTTAGAGGCATTATAAGAAAATTTTGAGTATA
+GGTTAGCTTTTAATTATGAATCTTATTGAAATTTGATTAATAAATATATGATAGGGGATT
+AAAATGAAACTATTTTATATCGTATTTCTTATTATTATATGGCTGAATATATTTTTAGGA
+AATGAAATTATCCATACACTGACTGTTTTAATAACAACATTGTATATTGTTAATTCAAGA
+AAGGGGATTAAAAATGACAGAGTTGAATAATATTATAAACTCTCTTCAATCTTTGTTTGA
+GTCTGAATCAGGCTATAAAATTTCGAAAAATTCAGGAGTTCCATATCAAACAGTACAAGA
+TTTAAGAAATGGGAAAACCAAACTAGAAGATGCTAGATTTAGAACGATTATTAAACTTTA
+TAGTTACTATGTCTCATTAAAAGAACATTAATCATGGGACAATAAAGTATTGCTATAATA
+ATTGAATCATTAAATGAAGGAATAGAGCCTAAGACATAATAAATCAATGTCTTAGGCTCT
+ACAATATTATATTGGTAGTAGTTGACCGAATGAAAATGACCATGTAACAAGCATTTTTGG
+GGCCCCAACACAGAAGCTGACGAAAAGTCAGCTTACAATAATGTGCAAGTTGGGGATGGG
+CCCCAACACAGAGAATTTCAAAAAGAAATTCTACAGACAATGCAAGTTGGCGGGGCCCCA
+ACATAGAGAAATTCAAAAAGAAATTCTACAGACAATGCAAGTTGGGGAGTGACAACGAAA
+TAAATTTTATAAAATACCATTTCTGTCACATTCCTACTCCCAATTCCATTTAAATATATA
+GAAAATTTCACCTATTATATACATCATACACTTTAAAAATTATCATTTAAATAATCTGAT
+TTGGAATTAAAGTGCATGAAGTATAAGTCACCTTCATATACTAATCAAAGAGGACGTCAA
+CAGTTATTTTATTAGGATTTTTAACATAAACATTTGCTAGATCTGAATGTAATCTTTTGC
+TTAAATCAATAGTGTAGTTATTACCGCCACCGGTGATCTTAAGCTTACCTTTATTACGAT
+TTTCGGTATATAATATTTTATTTTTTATTAACGCTTCTCGTGCACGGAAATCGATTTCTT
+TCAATGTTAATACTGGTTTATTGCCTTGGTATATTTTATGCGCACCAATAATCGTTTGTA
+GTTTATCTTTGTATTGCACAAAAAGATTATAAGTTTTATCAGAAGGTTTTGCGGCTGGTG
+TAACGCCACCTGTAAATGTCTCTCTATAAGACCACCATAACTGATCAGTATCTTTGTCTT
+TTAGTCCAAACACATCTACGTAACGATCTTTTAACTGATTAATATTTCCCCAACTTTCAG
+CGCCCCATAAAGATATATGTGCTGACCATGAATATCTCTTAAGTTCAACATAAATGTTTC
+CATTATCATATTGATATAGCCATTTATTTGAAAATGAAAAATGAGGCTGTGTGTAATATT
+TAATTAATTCATTGATGTTAGTTTCATCTTGACCAATGCTATAAGCTTTAGCTTCAGAGT
+AAAAACTAAATACTGGTTTTTGATTTTGAGGTAATACAGTACCTAATAGTAATAATGTTG
+TCGTTAAAATTATATTTTTCGTGATGTTCTTACTCATTAGAACATCTCCTTTCAGAGGAA
+TCATGATACGAGGAATAAGAAATTTAAATGTGAGCGAAGTCAATATAGTATTTGCGATTA
+TTTTTATTAACTCCATTATTATTGTTAGTTTGATTTTTCGAGGATAACTTCAATTTTTGC
+ATTTTGAGGTTTTTTAACATATCTATTTGCATCAGTTGATGGCAACCTTTTACTTAAATC
+TATTGTGTAGTTATTGTCTGTACCTGTTATTTTAATTTGTCCTTTATTATAAGAATTATT
+ATATAATTTTTTACTTTTAATTAATGTTTGACGAATACGAAAATCTAATTCTTTTAAAGT
+TAAAACAGGCTTATTGCCTTCATAAACTGGAAATCCGCCAGTAAACGTTTCTGCTTTATC
+TTTATATGTTACATTCAGTTTATAGTGTTTATCGTTAGATGTTGCTGCAGGAGTAACACC
+ACCAGTAAACGTTTCTTGAGATAATGCAAAAGAATCAATGGTTTCTTGGTCTTTTATGCC
+AAAAATATCAACGCTTTTATTTCTTAATTGGTTGATATTGCCCCAACTTTCAGGTCCATA
+AACTTGAATATGACTATACCAAGAAAACTGTAACAACGTTGCATGAATCGTACCGTTATC
+TTTTTGCCATAACGTACTGTTAGAGAAGGTTAAATATTTTTGCGAGTAATATTTAGTTAA
+CTCATTAACGTTAGTTTCGTTTTGATTTATATAATAAGCTTTCGCTTCAGATGAAGAATT
+GATAGGTGTATTAGGAAATTGTGTAAATGCTGTACCTAATAGTAACAATGTTGTTGATAA
+AATAATTTTTTTCGTGATGTTATTGTTCATTCGAATTTCTCCTTTGAGTATTGTTGGAAT
+GTTTAATTATAAAAAGGGGTTAATTAGATAATTGAAATTATCCGCATTTACAAAAGGTAA
+TAGGTTAGTTAGATTTTTCGAGTATGACTTCAATTTGTGCATTTTTAGGATTTTTAACAT
+AACGGTTTGTGTCAGTTAATTTTAACTTTTTACTTAAATCAATCGTGTAATTATTTCCAT
+CAGCAGTTATCTTAATTTGACCTTTATTAAATTCTCCGTTATATAACTTTTTATTCTTTA
+TTAATGTTTGACGAATACGGAAATCTAATTCTTTTAAAGTTAATACTGGTTTATTTCCTT
+TGTAAAATTCATGTCCACCGATGATAGTTTGTTGTTTATCACTATATTTTAAAAATAGTC
+TATAAGGTTTATCAGATGAAGTAGCTGCTGGCGTAACACCACCAGTAAATGTTTCATCAT
+AAGTCCAGTAACCTTCAACTGTGTCCTCATCTTTAGTTCCAAATATATCAACGTATTTAT
+TTCTTAACTGATTAATGTTTCCCCAACTCTCGGATCCAAACACTTGAATATGACTATACC
+AAACCCACGTTTGCAATGTTGCATGAATGCTACCATTGGGCTTTTGCCATAGCCATTTTC
+CAGATAATGAAAAATGCGGCTGAGTGTAATATTTGATTAACTCATTGATATTAGTCTCGT
+TTTCACTGATATTATAGGCTTTTGCTTCAGATGAAAAACTGATTGGTGTTTTAGGAAGTT
+GTGTTGATGTGGTTCCTAAAAGTAACAATGCTGTTGATAAAACTAATTTATTCATGATGT
+TCTTTTTCATATGAAAATCTCCTTTGCGTGAATTACCCAAAGTATATAAGCTATTACACC
+GATTCGGAATTAAATAAAAGCTAAAACTATGTTAAATAAACTTAAACAGTTAGTAGTGTT
+ATTTAAGCAAAACTTATCATTTTTAAGTTTTGGACAGAAACAGTACTTAATAAAGTAGGC
+GGGAGTTATATATTAAAAACGACACGTTACAATTATTCTCTAATCAATTGCATTAAATTG
+TTTGATAATTGAATTTTCTAACTACTTGAAAAATAGTTATACTTTAAATGTAGTACTTAT
+TTTAATTATTTCCTACTACTTAAATTTAATATTAATAAAATGTTCATTTAATTATTGATA
+AAATATTACAAATTTTAATAGTAGGTTGTGTTTATTTTGTATGCGCTTACAATTTAGGTG
+TAACTAAAATAAAAGGAGTTGTTATTAATGAAAAATTTACGAAACAGAAGTTTTTTAACT
+TTATTAGACTTTTCACGACAAGAGGTAGAATTCTTATTAACACTCTCCGAGGATTTAAAA
+CGTGCTAAATATATTGGCACTGAAAAGCCTATGTTAAAAAATAAAAATATTGCACTGTTA
+TTTGAAAAAGATTCTACAAGAACGCGATGTGCATTTGAAGTTGCAGCGCATGATCAAGGT
+GCAAATGTAACTTATTTAGGCCCAACTGGATCACAAATGGGTAAAAAAGAAACAACTAAA
+GATACTGCACGTGTGCTTGGTGGAATGTATGATGGCATTGAATACCGTGGTTTTTCACAA
+AGAACAGTAGAAACTTTAGCTGAAAATTCAGGCGTACCAGTGTGGAATGGTTTAACTGAT
+GAAGATCATCCTACTCAAGTTCTTGCTGATTTCTTAACAGCAAAAGAAGTCTTAAAAAAA
+GATTATGCAGATATTAACTTTACATATGTTGGAGATGGTCGTAATAACGTTGCAAATGCA
+TTAATGCAAGGTGCTGCCATTATGGGTATGAACTTCCATTTAGTTTGTCCAAAAGAATTA
+AATCCAACAGATGAATTATTAAATCGCTGTAAAAATATTGCCGCTGAAAATGGTGGCAAC
+ATATTAATCACAGATGATATTGACCAAGGTGTAAAAGGTTCGGATGTAATTTACACTGAT
+GTTTGGGTATCAATGGGTGAACCTGATGAAGTATGGAAAGAACGACTTGAATTATTGAAA
+CCATATCAAGTAAATAAAGAAATGATGGATAAAACTGGTAATCCAAATGTTATTTTTGAG
+CATTGCTTACCATCTTTCCATAATGCTGATACGAAAATTGGTCAACAAATTTTTGAAAAA
+TATGGTATTCGAGAAATGGAAGTTACAGATGAAGTATTCGAAAGTAAAGCTTCAGTTGTA
+TTCCAAGAAGCTGAGAACAGAATGCATACAATCAAAGCAGTCATGGTTGCTACATTGGGT
+GAATTTTAAATGATATAAGGAAGTGAATATGATGGCGAAAATAGTAGTAGCATTAGGTGG
+TAATGCTTTAGGAAAATCACCTCAAGAACAACTCGAGCTTGTTAAAAATACTGCGAAATC
+ATTAGTAGGATTAATAACAAAAGGACATGAGATTGTTATTAGTCATGGTAATGGACCACA
+GGTTGGAAGCATTAATTTGGGACTTAACTATGCTGCAGAACATAACCAAGGTCCGGCATT
+TCCATTTGCTGAATGTGGCGCAATGAGTCAAGCTTACATCGGCTATCAATTACAAGAAAG
+CTTACAAAATGAATTGCATTCTATTGGAATGGATAAACAAGTGGTAACACTAGTGACACA
+AGTTGAAGTTGATGAAAATGATCCGGCATTTAACAATCCTTCAAAACCAATTGGGTTATT
+TTACAACAAAGAAGAAGCTGAACAAATTCAAAAAGAAAAAGGATTTATATTTGTTGAAGA
+TGCTGGAAGAGGATATAGACGCGTTGTTCCTTCACCACAACCCATCTCTATTATTGAATT
+AGAGAGTATTAAAACACTTATTAAAAATGATACACTCGTTATTGCTGCTGGTGGTGGAGG
+TATACCAGTAATTAGAGAGCAACATGATGGTTTTAAAGGTATTGATGCAGTTATAGACAA
+AGATAAAACAAGTGCGTTGTTGGGTGCTAATATTCAATGCGATCAATTGATTATTTTAAC
+AGCAATTGATTATGTATATATTAATTTTAACACTGAAAACCAACAGCCTTTGAAAACAAC
+AAATGTTGATGAATTAAAACGATATATAGACGAAAATCAATTTGCAAAAGGAAGTATGTT
+ACCAAAAATTGAAGCAGCCATATCATTTATTGAAAACAATCCAAAAGGAAGTGTGCTTAT
+AACATCATTAAATGAATTAGATGCTGCCTTAGAGGGTAAAGTAGGTACTGTGATTAAAAA
+GTAATTGAATTGAAACGCTTTTCAATTACTATATGTCAAATGCATGATTTTTATTATTTA
+TGTGCACCCCCTGAAAATAATGCCTCTATTTTGATGCGGGGTGCACTTTCTTAATTTATA
+TTTATAAAATCTTTAAGGTAGAAATGCTAGGTTAAATGTCGAAGGAGATGAAACCGTGGA
+AAATACAATTAATGAAAGTGAAAAGAAAAAACGATTTAAATTAAAAATGCCAGGTGCATT
+TATGATTTTATTCATTTTAACGGTTGTTGCAGTTATAGCAACATGGGTTATTCCTGCTGG
+TGCATATTCTAAACTTTCTTACGAACCTTCATCCCAAGAACTAAAGATAGTTAACCCTCA
+TAACCAAGTGAAAAAGGTTCCGGGTACGCAACAGGAACTAGACAAAATGGGGGTTAAAAT
+TAAGATTGAACAATTTAAATCAGGTGCAATTAATAAGCCAGTATCAATTCCGAATACTTA
+TGAAAGATTAAAGCAACATCCAGCTGGACCAGAACAAATAACAAGTAGCATGGTTGAAGG
+TACGATAGAAGCGGTCGATATCATGGTATTCATTCTTGTACTAGGGGGACTTATTGGCGT
+AGTTCAAGCCAGTGGTTCTTTTGAATCGGGATTGTTAGCTTTAACGAAGAAAACAAAAGG
+GCATGAATTTATGCTAATTGTGTTTGTATCAATACTAATGATTATCGGCGGGACGTTATG
+TGGTATTGAAGAAGAAGCTGTAGCATTCTATCCGATTTTAGTCCCTATATTTATAGCGTT
+AGGATACGATTCTATCGTTTCAGTTGGTGCCATATTCCTTGCCAGCTCTGTCGGTAGTAC
+ATTTTCAACTATTAACCCGTTCTCGGTTGTAATTGCCTCTAATGCCGCTGGTACAACTTT
+TACGGATGGCTTGTATTGGAGAATAGGTGCTTGTATTGTCGGTGCGATTTTTGTTATTAG
+TTATTTATATTGGTACTGTAAAAAAATTAAAAACGATCCTAAAGCGTCATATTCTTATGA
+AGACAAAGATGCTTTTGAACAGCAATGGTCTGTATTAAAAGATGACGATAGTGCCCATTT
+TACTTTGCGTAAGAAGATAATCCTTACATTATTTGTACTACCATTTCCAATTATGGTATG
+GGGAGTTATGACGCAAGGTTGGTGGTTCCCAGTTATGGCTTCAGCATTTTTAATATTTAC
+AATTATAATAATGTTTATTGCTGGGACAGGTAAATCTGGATTGGGAGAAAAAGGAACTGT
+AGATGCATTTGTCAATGGTGCATCAAGTTTAGTAGGTGTATCTTTAATTATTGGTTTAGC
+TCGAGGTATTAATTTAGTGTTGAATGAAGGTATGATTTCAGATACAATCTTACACTTTTC
+ATCATCTTTAGTTCAACATATGAGTGGACCATTATTTATCATCGTATTACTATTTATTTT
+CTTCTGTTTAGGTTTTATCGTGCCATCATCTTCTGGATTAGCGGTATTATCAATGCCTAT
+CTTTGCACCACTAGCTGATACAGTAGGTATACCAAGATTCGTCATCGTTACGACATATCA
+ATTTGGTCAATATGCGATGTTATTCTTAGCGCCGACTGGACTTGTTATGGCCACACTACA
+AATGTTAAACATGCGATATTCACATTGGTTCCGATTTGTATGGCCGGTAGTTGCTTTTGT
+ATTGATTTTCGGTGGCGGAGTACTAATTACGCAAGTACTAATTTATTCATAATTTGAAAT
+GCTATATTATAAAAATACTAATTGGGTTTTATGCATCTCGTAGGTTTGTAGAAATACTAA
+ACTAAGCGAGGTGCATTATTATTTTTGATTAAGAAAATAATGACGGTAATGATAACACTA
+GTAAGTAATTGATACAATGCTCTATTTAATAATGATATTTTTAAAATTTGTTTTTAATGT
+AATGTTAGATCTATGGTATATTATATTTATCGTGGTAAATATGTATTTGCTGTAAACAGT
+TTTTGTAACACATGACACATATGGTTGTGAAAATAGCATATATAAAGGATGGCTATAAAT
+GACACATTTGACAAAGGTTTTAGATACACTAACTGGAATATGCGTAGTATTATTATTTAG
+TAAATATTTTGTGGCGTATGCAAATATGGTGTTTGATTGGAATTTAAGATGGTATTTGCT
+AGAAAACATACCACATTTGCCAATTATATTATTTATTCTGATGTTTATTTTCGGAGTACC
+TTCTGAAATGATAAAAGATAGGCAAAGGAAAAATAACGGTGTTTAATTTATCGATATTTA
+GAGGTGATAAAATTTGTCAACTATTACAAAGACTAAAATAAAAATCTTTATTAATTATTT
+TATTGGTATATTAGCCTTGGCGTTTGCTGCTTATATATTATTTAAATAAAGGTTAGAGTG
+AAACGTGTTTATGAACTAGACGTTCTAGTATAGTTACTACAGCTTTAGTCAGAAGGTATC
+ATTGATAAGATCATATTAAATCAAAGAGGCATTGATATACACTAAAAAGAGGCAAGATTA
+CCTGCCTCTTTTTTAGTTATTAAATATGCGTGTTAATTCTTGGTAATAGTGTTACTGAGA
+CGCATTACGAAGAAATTTATCTTGATTTTCCTTTTTTAAAAAGAAGTGAAGATATCCTAT
+AAAGACTCTAAGTACTATTACAGTGGCTAATAACACTTCGATAAACAAAAGACCTTTCCA
+AATATCTGGAAACATAAGTACAGGCAAACTGTTCTTTAAAGCAGTTGCTGAGATTACTAA
+AGGGAATGTGAAAGCTGAAAATACGGGCGAAAAAGGTTCTTTTAGTAATTTAGGCAATTG
+TATAATGATATAAAAATAAAATATTTGAGCTAATATTAAAAATATAATTACGATAAAAGC
+ATTCGCCTTAGGAAAGGCTATAACATATGCTGCAGCGACTAAAGAAAATGGTGCACAAAT
+TGTCGATGTGTTCGGTTTGATTGACGTCTGCAATGGAAATGCTTTTAATCGCTTGAAAAC
+AATAGGTAAGACAATACAAGTAGCTACAAAGCCATATATTACTGTTAATTGACCTATGAA
+AAAACATCCGCTAACGGGTGCCGTCAATCCTGCGATAGCAATACCAATAAAAAGTACAGT
+CCACGAAGGATAAACATTTTCAAGTGAAAAATCTTTTAAATATTTTATTGAAAAAATAAT
+CATATGCGTCATAATTCCCACAAGGCATAAAATCCAAATAGGCGTTATTAAGCTATTGAT
+AAAAGTTATGTTACTAAAAAATGTATTTAAATAAGTAGTACCTAAAAAGCCAGACATGAA
+AAATGTTGTGAACACTGATGAAACTAGAGGACTGTTTAATTGTTCTTTCACATTATTAAA
+ATATTTGATCATAGTACATAAAAGGTGAATCCAAATCAAGAAAGCAAAGATTCCGCAAAC
+AGCGTTTAAAGTAAGAGATAAGTCTTTTAATAGATTACCCAGGCCTAATAATCCTAAGAC
+TAGTCCTGACGTTACTAGAGGTGCTTTTTGAAGTCTCATGATTTACAACCTTTCTTATGT
+GATTTTCTTCACTAATTATATCATGATAGCTATGGCCAATTAATAAGAAGAGTGTGTACT
+ATTACGTTATTAGAGTATGTATATTGGATTGATAGACACATAATTGACATTTAAATCTCA
+AAATTAATGATATTTGAGGTATGCTTTGCAACCTAAATATTGGAATATGTGGAAAAGTAA
+TTATTTAATTTAAATGATGATTGAAGATTTACAAGGGGGTGTACAAAATGAGAAATCAAA
+TTCAAAAACTATTAGACAGTGATTTGAGCAGTTTACATATATCGAAACAAACAGGAGTTC
+CACAAAGCACAATACACAGAATGAGAAAAAAAGAAAGATCATTAGACAATATGTCATTGA
+AAAACGCTGAACTACTTTATAAATTTGCCAATAGTATATTTAGCAATGAAAATTAAGAAG
+AATAATTAGTGAGTTAAATAATTAAAAAACCACGTCTCGATGGACGTGGTTATTTTTTTA
+AATGTATTTAATTATAGGATTTCGGGCCCCTGAAAAGTCCCTAAAATTTTGAATAGTATC
+AAAATCTATAGGAATAATATAATAATAAAAATCTCTACGCATGCAAATGGTGAGTGTTAA
+AAATCTTGGTGTAGTGTTGGTGTAGTTCAGGTGCAGTATAGATGAAATTTGAGCACAAAA
+TTACTTAATTAAAAATGTATAAACAAGTGTCAGACGCGTGTCAATTGTGTGTCAAAAAAT
+TCTATGACGAATAAGCATGCTTGTTTTAATTACTGTATTTTCGGGGCTTATGCGGGGGAC
+GTTTTGGTGACGCATCATACTATATTACTGAAATTCAAAACAAAAAGAGCCCCGTAATCA
+CGGAACTCTTTTGTTTGGTAATGCGTATAAAAATACCTATAAACGTCCTGGGAGGGATTC
+GAACCCCCGACCGATGGCTTAGAAGGCCATTGCTCTATCCAGCTGAGCTACCAGGACACG
+TTTAACAACACAAGAATTATTATATCTAAATGAACTTAAATTAGCAATACCTTGTAAATA
+AAAAATGTTTATATTTTTCACTATTATAGAGCTATTTATCTAAAAAGGTTCAATAAGACT
+TAAATGCGAATTCAGGCAACTTAATTGTGTTAAATACAGTTTTGAATGCCTAACTGTATT
+TCTTTTCTCTTTAAAATACAGTTAAGTACATTATAAGATGTTGTGCGGATAAACAAACTA
+ATTGCATCAAATTTATTTTAAAATAACAACAACAAAACGTTAAGCGAATAACATTTCGGT
+GATTTAAAAGCTACGCACGTTTTTGTTATCTTCAAATTTAAATTTTAAGGAGTGTTTTCA
+ATGGAAGGTTTATTTAACGCAATTAAAGATACCGTAACTGCAGCAATTAATAATGATGGC
+GCAAAATTAGGCACAAGCATTGTGAGCATCGTTGAAAATGGCGTAGGTTTATTAGGTAAA
+TTATTCGGATTCTAATTTCAATATGTTATGTAAGTAATCAGTATTATTTCAAAGGTGAGG
+GAGAGATTTAAATGACTGGACTAGCAGAAGCAATCGCAAATACTGTGCAAGCTGCACAAC
+AACATGATAGTGTGAAATTAGGCACAAGTATCGTAGACATCGTTGCTAACGGTGTGGGTT
+TACTAGGTAAATTATTTGGATTCTAATATAATAACTAATATTCTTTAAAATAAACTGGGT
+GAGCATACTTTAATGTTATGCACTCAGTTTATTTTATTTGCAGAAATTTGAGCCTCTGTT
\ No newline at end of file
diff --git a/t/data/reorder_isolates.tre b/t/data/reorder_isolates.tre
new file mode 100644
index 0000000..0119bd7
--- /dev/null
+++ b/t/data/reorder_isolates.tre
@@ -0,0 +1 @@
+(query_1:6.0,(query_3:5.0,query_4:3.0):5.0,query_2:11.0);
\ No newline at end of file
diff --git a/t/data/reorder_isolates_expected_output.csv b/t/data/reorder_isolates_expected_output.csv
new file mode 100644
index 0000000..57e20f7
--- /dev/null
+++ b/t/data/reorder_isolates_expected_output.csv
@@ -0,0 +1,8 @@
+"Gene","Non-unique Gene name","Annotation","No. isolates","No. sequences","Avg sequences per isolate","Genome Fragment","Order within Fragment","Accessory Fragment","Accessory Order with Fragment","QC","query_1","query_2","query_3"
+"hly","","Alpha-toxin","3","3","1","","","","","","1_1","2_1","3_1"
+"argF","","Ornithine carbamoyltransferase","2","2","1","","","","","","1_3","","3_3"
+"group_4","","","2","2","1","","","","","","","2_4","3_4"
+"speH","","hypothetical protein","2","2","1","","","","","","1_2","2_2",""
+"group_7","","Gonococcal growth inhibitor III","1","1","1","","","","","","","2_7",""
+"yfnB","","Putative HAD-hydrolase yfnB","1","1","1","","","","","","","","3_5"
+"group_6","","Gonococcal growth inhibitor III","1","1","1","","","","","","1_6","",""
diff --git a/t/data/reorder_isolates_expected_output_breadth_alpha.csv b/t/data/reorder_isolates_expected_output_breadth_alpha.csv
new file mode 100644
index 0000000..57e20f7
--- /dev/null
+++ b/t/data/reorder_isolates_expected_output_breadth_alpha.csv
@@ -0,0 +1,8 @@
+"Gene","Non-unique Gene name","Annotation","No. isolates","No. sequences","Avg sequences per isolate","Genome Fragment","Order within Fragment","Accessory Fragment","Accessory Order with Fragment","QC","query_1","query_2","query_3"
+"hly","","Alpha-toxin","3","3","1","","","","","","1_1","2_1","3_1"
+"argF","","Ornithine carbamoyltransferase","2","2","1","","","","","","1_3","","3_3"
+"group_4","","","2","2","1","","","","","","","2_4","3_4"
+"speH","","hypothetical protein","2","2","1","","","","","","1_2","2_2",""
+"group_7","","Gonococcal growth inhibitor III","1","1","1","","","","","","","2_7",""
+"yfnB","","Putative HAD-hydrolase yfnB","1","1","1","","","","","","","","3_5"
+"group_6","","Gonococcal growth inhibitor III","1","1","1","","","","","","1_6","",""
diff --git a/t/data/reorder_isolates_expected_output_breadth_creation.csv b/t/data/reorder_isolates_expected_output_breadth_creation.csv
new file mode 100644
index 0000000..57e20f7
--- /dev/null
+++ b/t/data/reorder_isolates_expected_output_breadth_creation.csv
@@ -0,0 +1,8 @@
+"Gene","Non-unique Gene name","Annotation","No. isolates","No. sequences","Avg sequences per isolate","Genome Fragment","Order within Fragment","Accessory Fragment","Accessory Order with Fragment","QC","query_1","query_2","query_3"
+"hly","","Alpha-toxin","3","3","1","","","","","","1_1","2_1","3_1"
+"argF","","Ornithine carbamoyltransferase","2","2","1","","","","","","1_3","","3_3"
+"group_4","","","2","2","1","","","","","","","2_4","3_4"
+"speH","","hypothetical protein","2","2","1","","","","","","1_2","2_2",""
+"group_7","","Gonococcal growth inhibitor III","1","1","1","","","","","","","2_7",""
+"yfnB","","Putative HAD-hydrolase yfnB","1","1","1","","","","","","","","3_5"
+"group_6","","Gonococcal growth inhibitor III","1","1","1","","","","","","1_6","",""
diff --git a/t/data/reorder_isolates_expected_output_breadth_height.csv b/t/data/reorder_isolates_expected_output_breadth_height.csv
new file mode 100644
index 0000000..57e20f7
--- /dev/null
+++ b/t/data/reorder_isolates_expected_output_breadth_height.csv
@@ -0,0 +1,8 @@
+"Gene","Non-unique Gene name","Annotation","No. isolates","No. sequences","Avg sequences per isolate","Genome Fragment","Order within Fragment","Accessory Fragment","Accessory Order with Fragment","QC","query_1","query_2","query_3"
+"hly","","Alpha-toxin","3","3","1","","","","","","1_1","2_1","3_1"
+"argF","","Ornithine carbamoyltransferase","2","2","1","","","","","","1_3","","3_3"
+"group_4","","","2","2","1","","","","","","","2_4","3_4"
+"speH","","hypothetical protein","2","2","1","","","","","","1_2","2_2",""
+"group_7","","Gonococcal growth inhibitor III","1","1","1","","","","","","","2_7",""
+"yfnB","","Putative HAD-hydrolase yfnB","1","1","1","","","","","","","","3_5"
+"group_6","","Gonococcal growth inhibitor III","1","1","1","","","","","","1_6","",""
diff --git a/t/data/reorder_isolates_expected_output_breadth_revalpha.csv b/t/data/reorder_isolates_expected_output_breadth_revalpha.csv
new file mode 100644
index 0000000..57e20f7
--- /dev/null
+++ b/t/data/reorder_isolates_expected_output_breadth_revalpha.csv
@@ -0,0 +1,8 @@
+"Gene","Non-unique Gene name","Annotation","No. isolates","No. sequences","Avg sequences per isolate","Genome Fragment","Order within Fragment","Accessory Fragment","Accessory Order with Fragment","QC","query_1","query_2","query_3"
+"hly","","Alpha-toxin","3","3","1","","","","","","1_1","2_1","3_1"
+"argF","","Ornithine carbamoyltransferase","2","2","1","","","","","","1_3","","3_3"
+"group_4","","","2","2","1","","","","","","","2_4","3_4"
+"speH","","hypothetical protein","2","2","1","","","","","","1_2","2_2",""
+"group_7","","Gonococcal growth inhibitor III","1","1","1","","","","","","","2_7",""
+"yfnB","","Putative HAD-hydrolase yfnB","1","1","1","","","","","","","","3_5"
+"group_6","","Gonococcal growth inhibitor III","1","1","1","","","","","","1_6","",""
diff --git a/t/data/reorder_isolates_expected_output_depth_alpha.csv b/t/data/reorder_isolates_expected_output_depth_alpha.csv
new file mode 100644
index 0000000..57e20f7
--- /dev/null
+++ b/t/data/reorder_isolates_expected_output_depth_alpha.csv
@@ -0,0 +1,8 @@
+"Gene","Non-unique Gene name","Annotation","No. isolates","No. sequences","Avg sequences per isolate","Genome Fragment","Order within Fragment","Accessory Fragment","Accessory Order with Fragment","QC","query_1","query_2","query_3"
+"hly","","Alpha-toxin","3","3","1","","","","","","1_1","2_1","3_1"
+"argF","","Ornithine carbamoyltransferase","2","2","1","","","","","","1_3","","3_3"
+"group_4","","","2","2","1","","","","","","","2_4","3_4"
+"speH","","hypothetical protein","2","2","1","","","","","","1_2","2_2",""
+"group_7","","Gonococcal growth inhibitor III","1","1","1","","","","","","","2_7",""
+"yfnB","","Putative HAD-hydrolase yfnB","1","1","1","","","","","","","","3_5"
+"group_6","","Gonococcal growth inhibitor III","1","1","1","","","","","","1_6","",""
diff --git a/t/data/reorder_isolates_expected_output_depth_creation.csv b/t/data/reorder_isolates_expected_output_depth_creation.csv
new file mode 100644
index 0000000..57e20f7
--- /dev/null
+++ b/t/data/reorder_isolates_expected_output_depth_creation.csv
@@ -0,0 +1,8 @@
+"Gene","Non-unique Gene name","Annotation","No. isolates","No. sequences","Avg sequences per isolate","Genome Fragment","Order within Fragment","Accessory Fragment","Accessory Order with Fragment","QC","query_1","query_2","query_3"
+"hly","","Alpha-toxin","3","3","1","","","","","","1_1","2_1","3_1"
+"argF","","Ornithine carbamoyltransferase","2","2","1","","","","","","1_3","","3_3"
+"group_4","","","2","2","1","","","","","","","2_4","3_4"
+"speH","","hypothetical protein","2","2","1","","","","","","1_2","2_2",""
+"group_7","","Gonococcal growth inhibitor III","1","1","1","","","","","","","2_7",""
+"yfnB","","Putative HAD-hydrolase yfnB","1","1","1","","","","","","","","3_5"
+"group_6","","Gonococcal growth inhibitor III","1","1","1","","","","","","1_6","",""
diff --git a/t/data/reorder_isolates_expected_output_depth_height.csv b/t/data/reorder_isolates_expected_output_depth_height.csv
new file mode 100644
index 0000000..57e20f7
--- /dev/null
+++ b/t/data/reorder_isolates_expected_output_depth_height.csv
@@ -0,0 +1,8 @@
+"Gene","Non-unique Gene name","Annotation","No. isolates","No. sequences","Avg sequences per isolate","Genome Fragment","Order within Fragment","Accessory Fragment","Accessory Order with Fragment","QC","query_1","query_2","query_3"
+"hly","","Alpha-toxin","3","3","1","","","","","","1_1","2_1","3_1"
+"argF","","Ornithine carbamoyltransferase","2","2","1","","","","","","1_3","","3_3"
+"group_4","","","2","2","1","","","","","","","2_4","3_4"
+"speH","","hypothetical protein","2","2","1","","","","","","1_2","2_2",""
+"group_7","","Gonococcal growth inhibitor III","1","1","1","","","","","","","2_7",""
+"yfnB","","Putative HAD-hydrolase yfnB","1","1","1","","","","","","","","3_5"
+"group_6","","Gonococcal growth inhibitor III","1","1","1","","","","","","1_6","",""
diff --git a/t/data/reorder_isolates_expected_output_depth_revalpha.csv b/t/data/reorder_isolates_expected_output_depth_revalpha.csv
new file mode 100644
index 0000000..57e20f7
--- /dev/null
+++ b/t/data/reorder_isolates_expected_output_depth_revalpha.csv
@@ -0,0 +1,8 @@
+"Gene","Non-unique Gene name","Annotation","No. isolates","No. sequences","Avg sequences per isolate","Genome Fragment","Order within Fragment","Accessory Fragment","Accessory Order with Fragment","QC","query_1","query_2","query_3"
+"hly","","Alpha-toxin","3","3","1","","","","","","1_1","2_1","3_1"
+"argF","","Ornithine carbamoyltransferase","2","2","1","","","","","","1_3","","3_3"
+"group_4","","","2","2","1","","","","","","","2_4","3_4"
+"speH","","hypothetical protein","2","2","1","","","","","","1_2","2_2",""
+"group_7","","Gonococcal growth inhibitor III","1","1","1","","","","","","","2_7",""
+"yfnB","","Putative HAD-hydrolase yfnB","1","1","1","","","","","","","","3_5"
+"group_6","","Gonococcal growth inhibitor III","1","1","1","","","","","","1_6","",""
diff --git a/t/data/reorder_isolates_input.csv b/t/data/reorder_isolates_input.csv
new file mode 100644
index 0000000..4747e68
--- /dev/null
+++ b/t/data/reorder_isolates_input.csv
@@ -0,0 +1,8 @@
+"Gene","Non-unique Gene name","Annotation","No. isolates","No. sequences","Avg sequences per isolate","Genome Fragment","Order within Fragment","Accessory Fragment","Accessory Order with Fragment","QC","query_1","query_2","query_3"
+"hly","","Alpha-toxin","3","3","1","","","","","","1_1","2_1","3_1"
+"argF","","Ornithine carbamoyltransferase","2","2","1","","","","","","1_3","","3_3"
+"group_4","","","2","2","1","","","","","","","2_4","3_4"
+"speH","","hypothetical protein","2","2","1","","","","","","1_2","2_2",""
+"group_7","","Gonococcal growth inhibitor III","1","1","1","","","","","","","2_7",""
+"yfnB","","Putative HAD-hydrolase yfnB","1","1","1","","","","","","","","3_5"
+"group_6","","Gonococcal growth inhibitor III","1","1","1","","","","","","1_6","",""
\ No newline at end of file
diff --git a/t/data/sequences_with_unknowns.faa b/t/data/sequences_with_unknowns.faa
new file mode 100644
index 0000000..9169433
--- /dev/null
+++ b/t/data/sequences_with_unknowns.faa
@@ -0,0 +1,26 @@
+>1234_00186 GGDEF family protein
+MNFENEYDLEKLVNNSLDLLTIVDLSGNVLLVNPAFERTLGWKKEDLVGKDPFHLLHPED
+KESTYKEFEKLNQGLLTLSFQNRYICADGQYRYFSWTASPDLVSGLVYVTGRDITDVIES
+NRKISQLAVKLKETNDRLFEQASTDPLTKLKNRRMFNEELNNLIHACDKESHPLSLLMID
+ADHFKDYNDKFGHIAGDKVLVELASILTKTFRKKDVLARYGGEEFIAALPNTSEPEANQI
+AERLVQTVREFSWEKRSVTISVGITTYNFNPTSKSINSEYLLNLIEQADKALYCSKVSGR
+XXXXXXXXXXXXXXXXXXXYYI*
+>1234_00325 only a few unknowns so keep
+MAFDPSVPQQQAQAPAGTLLFPEGSSANTLNVLHSGTVRYLTEVPGGRKLELFKLNGANL
+TPGSVALFTSGRYPFHLQAEEACVISTYAMNRDTISKSVGSRVSLGLMVARTLLREITEL
+FKKSNQIRKITSEIEKVNDNLSILYYQFNPSVFPDIKPGSPIPEVSADVVDPVMRLCREN
+LKLFFDNGGILPDRPSPQFLEEEHESQLTRLYPEEIDFQDGEFNFIRKLVMQDPKILNVL
+FTADPSMLAYVCSKLANVLDQISGILKTCLTDLDEAFRIFFIGENSLVEKFYLILDITSS
+GYGTAPAEFVIPVLGAFAGKIEKYKNGHQALFGVPVANISPNTQAFQSKAVTLAKKMEET
+APKVQAPVTSSATAGVDVDAIRKELDNSASVIIQFSGLGAEQIKEFSALMVKVKSLKNPL
+DPEGDNRKVRRTLGRHYWDMYQECFTKYMNSNRNVPKPVELMLKYGYFDETLVDDSQIAF
+MYTQKDPANFTSNVPISLGTEWLEKVFKREVPTSLDEMGQNFFEKVKLENRNIVIKKESD
+IPPELDNPDTRLKFEFASLYEANVRLTSGSPATHFPILTKFHSQMAIDKSYVSKKILEEV
+VHELMAVDYSIFHREVIYNNNELGITKEFIQKCVIPDFILVPSIGTKVMMWQDLSIHRGA
+GSKESPGRIVLPIFAQGDLKTMVADALAAFRWELTKSILGAEWNNVGNPSITADYTDYIQ
+FFKKNKDLSMEIKEKLASDFKRFRNDRDIFANDYQLWMKYEADGVQRLNKVVRGIFYRHI
+PFSKQVRDKVAXXXXXXXXXXXXXLLPLQRSITDLLILEIENILK*
+>1234_00377 Uncharacterized protein conserved in bacteria
+MTLNEFAKNVLFGSGLEDKLFSPPVHPVDIRSFDFLNVPSLPAREKKIQISEQKSKIPRL
+EQLFNEENRIITLHHFANHELMAIELFAWAILKFQDAPSSIRFGLYRTLLEEQTHLKMYL
+SEMKKGGMELGDRPLNFIFWKQVPKMQTLEKFXXXXXXXXXXXXXXXXXF*
diff --git a/t/data/shred1.gff b/t/data/shred1.gff
new file mode 100644
index 0000000..1df7f57
--- /dev/null
+++ b/t/data/shred1.gff
@@ -0,0 +1,9 @@
+##gff-version 3
+##sequence-region shredA 1 40
+##sequence-region shredB 1 40
+shredA Prodigal:2.60 CDS 179 1471 . - 0 ID=11983_1#21_00001;eC_number=2.7.13.3;gene=regB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_005150533.1,similar to AA sequence:UniProtKB:Q3J6C1,protein motif:CLUSTERS:PRK11360,protein motif:Cdd:COG4191,protein motif:TIGRFAMs:TIGR02966,protein motif:Pfam:PF02518.20;locus_tag=11983_1#21_00001;product=integral membrane sensor signal transduction histidine kinase,Sensor histidine kinase regB,sensory histidine kinase A [...]
+##FASTA
+>shredA
+AAAAAAAAAACCCCCCCCCCGGGGGGGGGGTTTTTTTTTT
+>shredB
+AAAAAAAAAACCCCCCCCCCGGGGGGGGGGTTTTTTTTTT
diff --git a/t/data/shred1.shred.fa b/t/data/shred1.shred.fa
new file mode 100644
index 0000000..6cc6a07
--- /dev/null
+++ b/t/data/shred1.shred.fa
@@ -0,0 +1,16 @@
+>shred1_1
+AAAAAAAAAA
+>shred1_2
+CCCCCCCCCC
+>shred1_3
+GGGGGGGGGG
+>shred1_4
+TTTTTTTTTT
+>shred1_5
+AAAAAAAAAA
+>shred1_6
+CCCCCCCCCC
+>shred1_7
+GGGGGGGGGG
+>shred1_8
+TTTTTTTTTT
diff --git a/t/data/shred2.gff b/t/data/shred2.gff
new file mode 100644
index 0000000..142a41e
--- /dev/null
+++ b/t/data/shred2.gff
@@ -0,0 +1,9 @@
+##gff-version 3
+##sequence-region shredA 1 40
+##sequence-region shredB 1 40
+shredA Prodigal:2.60 CDS 179 1471 . - 0 ID=11983_1#21_00001;eC_number=2.7.13.3;gene=regB;inference=ab initio prediction:Prodigal:2.60,similar to AA sequence:RefSeq:YP_005150533.1,similar to AA sequence:UniProtKB:Q3J6C1,protein motif:CLUSTERS:PRK11360,protein motif:Cdd:COG4191,protein motif:TIGRFAMs:TIGR02966,protein motif:Pfam:PF02518.20;locus_tag=11983_1#21_00001;product=integral membrane sensor signal transduction histidine kinase,Sensor histidine kinase regB,sensory histidine kinase A [...]
+##FASTA
+>shredA
+AAAAAAAAAAGGGGGGGGGGTTTTTTTTTTCCCCCCCCCC
+>shredB
+AAAAAAAAAACCCCCCCCCCTTTTTTTTTTGGGGGGGGGG
diff --git a/t/data/shred2.shred.fa b/t/data/shred2.shred.fa
new file mode 100644
index 0000000..1d474dd
--- /dev/null
+++ b/t/data/shred2.shred.fa
@@ -0,0 +1,16 @@
+>shred2_1
+AAAAAAAAAA
+>shred2_2
+GGGGGGGGGG
+>shred2_3
+TTTTTTTTTT
+>shred2_4
+CCCCCCCCCC
+>shred2_5
+AAAAAAAAAA
+>shred2_6
+CCCCCCCCCC
+>shred2_7
+TTTTTTTTTT
+>shred2_8
+GGGGGGGGGG
diff --git a/t/data/sopB.fa.aln b/t/data/sopB.fa.aln
new file mode 100644
index 0000000..b73d36b
--- /dev/null
+++ b/t/data/sopB.fa.aln
@@ -0,0 +1,60 @@
+>11111_1#11_04059
+ATGCAAATACAGAGCTTCTATCACTCAGCTTCACTAAAAACCCAGGAGGCTTTTAAAAGC
+CTACAAAAAACCTTATACAACGGAATGCAGATTCTCTCAGGCCAGGGCAAAGCGCCGGCT
+AAAGCGCCCGACGCTCGCCCGGAAATTATTGTCCTGCGAGAACCTGGCGCGACATGGGGG
+AATTATCTACAGCATCAGAAGACGTCTAACCACTCGCTGCATAACCTCTATAACTTACAG
+CGCGATCTTCTTACCGTCGCGGCAACCGTTCTGGGTAAACAAGACCCGGTTCTAACGTCA
+ATGGCAAACCAAATGGAGTTAGCCAAAGTTAAAGCGGACCGGCCAGCAACAAAACAAGAA
+GAAGCTGCGGCAAAAGCATTGAAGAAAAATCTTATCGAACTTATTGCAGCACGCACTCAG
+CAGCAAAATGGCTTACCTGCAAAAGAAGCTCATCGCTTTGCGGCAGTAGCGTTTAGAGAT
+GCTCAGGTCAAGCAGCTCAATAACCAGCCCTGGCAAACCATAAAAAATACACTCACGCAT
+AACGGGCATCACTATACCAACACGCAGCTCCCTGCCGCAGAGATGAAAATCGGCGCAAAA
+GATATCTTTCCCAGTGCTTATGAGGGAAAGGGCGTATGCAGTTGGGATACCAAGAATATT
+CATCACGCCAATAATTTGTGGATGTCCACGGTGAGTGTGCATGAGGACGGTAAAGATAAA
+ACGCTTTTTTGCGGGATACGTCATGGTGTGCTTTCCCCCTATCATGAAAAAGATCCGCTT
+CTGCGTCAGGCCGGCGCTGAAAACAAAGCCAAAGAAGTATTAGCTGCGGCACTTTTTAGT
+AAACCTGAGTTGCTTAACAGAGCCTTAGAGGGCGAAGCGGTAAGCCTGAAACTGGTATCC
+GTCGGGTTACTCACCGCGTCGAATATTTTCGGCAAAGAGGGAACTATGGTCGAGGATCAA
+ATGCGCGCATGGCAATCGTTGACCCAGCCGGGAAAAATGATTCATTTAAAAATCCGCAAT
+AAAGATGGCGATCTACAGACGGTAAAAATAAAACCGGACGTCGCCGCATTTAATGTGGGT
+GTTAATGAGCTGGCGCTCAAGCTCGGCTTTGGCCTTAAAGCATCAGATAGCTATAATGCC
+GAAGCGCTACATCAGTTATTAGGCAATGATTTACGCCCTGAAGCCAGACCAGGTGGCTGG
+GTTGGCGAATGGCTGGCGCAATACCCGGATAATTATGAGGTCGTCAATACATTAGCGCGC
+CAGATTAAGGATATCTGGAAAAATAACCAACATCATAAAGATGGCGGCGAACCCTATAAA
+CTCGCACAACGCCTTGCCATGTTAGCCCATGAAATTGACGCGGTGCCCGCCTGGAATTGT
+AAAAGCGGCAAAGATCGTACAGGGATGATGGATTCAGAAATCAAGCGAGAGCTCATTTCT
+TTCCATCAGACCCATATGTTAAGTGCGCCTGGTAGTCTTCCGGATAGCGGTGGACAGAAA
+ATTTTCCAAAAAGTATTACTGAATAGCGGTAACCTGGAGATTCAGAAACAAAATACGGGC
+GGGGCGGGAAACAAAGTAATGAAAAATTTATCGCCAGAGGTGCTCAATCTTTCCTATCAA
+AAACGAGTTGGGGATGAAAATATTTGGCAGTCAGTAAAAGGTATTTCTTCATTAATCACA
+TCT
+>22222_2#22_04059
+ATGCAAATACAGAGCTTCTATCACTCAGCTTCACTAAAAACCCAGGAGGCTTTTAAAAGC
+CTACAAAAAACCTTATACAACGGAATGCAGATTCTCTCAGGCCAGGGCAAAGCGCCGGCT
+AAAGCGCCCGACGCTCGCCCGGAAATTATTGTCCTGCGAGAACCTGGCGCGACATGGGGG
+AATTATCTACAGCATCAGAAGACGTCTAACCACTCGCTGCATAACCTCTATAACTTACAG
+CGCGATCTTCTTACCGTCGCGGCAACCGTTCTGGGTAAACAAGACCCGGTTCTAACGTCA
+ATGGCAAACCAAATGGAGTTAGCCAAAGTTAAAGCGGACCGGCCAGCAACAAAACAAGAA
+GAAGCTGCGGCAAAAGCATTGAAGAAAAATCTTATCGAACTTATTGCAGCACGCACTCAG
+CAGCAAAATGGCTTACCTGCAAAAGAAGCTCATCGCTTTGCGGCAGTAGCGTTTAGAGAT
+GCTCAGGTCAAGCAGCTCAATAACCAGCCCTGGCAAACCATAAAAAATACACTCACGCAT
+AACGGGCATCACTATACCAACACGCAGCTCCCTGCCGCAGAGATGAAAATCGGCGCAAAA
+GATATCTTTCCCAGTGCTTATGAGGGAAAGGGCGTATGCAGTTGGGATACCAAGAATATT
+CATCACGCCAATAATTTGTGGATGTCCACGGTGAGTGTGCATGAGGACGGTAAAGATAAA
+ACGCTTTTTTGCGGGATACGTCATGGTGTGCTTTCCCCCTATCATGAAAAAGATCCGCTT
+CTGCGTCAGGCCGGCGCTGAAAACAAAGCCAAAGAAGTATTAGCTGCGGCACTTTTTAGT
+AAACCTGAGTTGCTTAACAGAGCCTTAGAGGGCGAAGCGGTAAGCCTGAAACTGGTATCC
+GTCGGGTTACTCACCGCGTCGAATATTTTCGGCAAAGAGGGAACTATGGTCGAGGATCAA
+ATGCGCGCATGGCAATCGTTGACCCAGCCGGGAAAAATGATTCATTTAAAAATCCGCAAT
+AAAGATGGCGATCTACAGACGGTAAAAATAAAACCGGACGTCGCCGCATTTAATGTGGGT
+GTTAATGAGCTGGCGCTCAAGCTCGGCTTTGGCCTTAAAGCATCAGATAGCTATAATGCC
+GAAGCGCTACATCAGTTATTAGGCAATGATTTACGCCCTGAAGCCAGACCAGGTGGCTGG
+GTTGGCGAATGGCTGGCGCAATACCCGGATAATTATGAGGTCGTCAATACATTAGCGCGC
+CAGATTAAGGATATCTGGAAAAATAACCAACATCATAAAGATGGCGGCGAACCCTATAAA
+CTCGCACAACGCCTTGCCATGTTAGCCCATGAAATTGACGCGGTGCCCGCCTGGAATTGT
+AAAAGCGGCAAAGATCGTACAGGGATGATGGATTCAGAAATCAAGCGAGAGCTCATTTCT
+TTCCATCAGACCCATATGTTAAGTGCGCCTGGTAGTCTTCCGGATAGCGGTGGACAGAAA
+ATTTTCCAAAAAGTATTACTGAATAGCGGTAACCTGGAGATTCAGAAACAAAATACGGGC
+GGGGCGGGAAACAAAGTAATGAAAAATTTATCGCCAGAGGTGCTCAATCTTTCCTATCAA
+AAACGAGTTGGGGATGATAATATTTGGCAGTCAGTAAAAGGTATTTCTTCATTAATCACA
+TCT
diff --git a/t/data/speH.fa.aln b/t/data/speH.fa.aln
new file mode 100644
index 0000000..f6502a9
--- /dev/null
+++ b/t/data/speH.fa.aln
@@ -0,0 +1,32 @@
+>2_2
+ATGAACAATAACATCACGAAAAAAATTATTTTATCAACAACATTGTTACT
+ATTAGGTACAGCATTTACACAATTTCCTAATACACCTATCAATTCTTCAT
+CTGAAGCGAAAGCTTATTATATAAATCAAAACGAAACTAACGTTAATGAG
+TTAACTAAATATTACTCGCAAAAATATTTAACCTTCTCTAACAGTACGTT
+ATGGCAAAAAGATAACGGTACGATTCATGCAACGTTGTTACAGTTTTCTT
+GGTATAGTCATATTCAAGTTTATGGACCTGAAAGTTGGGGCAATATCAAC
+CAATTAAGAAATAAAAGCGTTGATATTTTTGGCATAAAAGACCAAGAAAC
+CATTGATTCTTTTGCATTATCTCAAGAAACGTTTACTGGTGGTGTTACTC
+CTGCAGCAACATCTAACGATAAACACTATAAACTGAATGTAACATATAAA
+GATAAAGCAGAAACGTTTACTGGCGGATTTCCAGTTTATGAAGGCAATAA
+GCCTGTTTTAACTTTAAAAGAATTAGATTTTCGTATTCGTCAAACATTAA
+TTAAAAGTAAAAAATTATATAATAATTCTTATAATAAAGGACAAATTAAA
+ATAACAGGTACAGACAATAACTACACAATAGATTTAAGTAAAAGGTTGCC
+ATCAACTGATGCAAATAGATATGTTAAAAAACCTCAAAATGCAAAAATTG
+AAGTTATCCTCGAAAAATCAAAC
+>1_2
+ATGAACAATAACATCACGAAAAAAATTATTTTATCAACAACATTGTTACT
+ATTAGGTACAGCATTTACACAATTTCCTAATACACCTATCAATTCTTCAT
+CTGAAGCGAAAGCTTATTATATAAATCAAAACGAAACTAACGTTAATGAG
+TTAACTAAATATTACTCGCAAAAATATTTAACCTTCTCTAACAGTACGTT
+ATGGCAAAAAGATAACGGTACGATTCATGCAACGTTGTTACAGTTTTCTT
+GGTATAGTCATATTCAAGTTTATGGACCTGAAAGTTGGGGCAATATCAAC
+CAATTAAGAAATAAAAGCGTTGATATTTTTGGCATAAAAGACCAAGAAAC
+CATTGATTCTTTTGCATTATCTCAAGAAACGTTTACTGGTGGTGTTACTC
+CTGCAGCAACATCTAACGATAAACACTATAAACTGAATGTAACATATAAA
+GATAAAGCAGAAACGTTTACTGGCGGATTTCCAGTTTATGAAGGCAATAA
+GCCTGTTTTAACTTTAAAAGAATTAGATTTTCGTATTCGTCAAACATTAA
+TTAAAAGTAAAAAATTATATAATAATTCTTATAATAAAGGACAAATTAAA
+ATAACAGGTACAGACAATAACTACACAATAGATTTAAGTAAAAGGTTGCC
+ATCAACTGATGCAAATAGATATGTTAAAAAACCTCAAAATGCAAAAATTG
+AAGTTATCCTCGAAAAATCAAAC
diff --git a/t/data/split_groups/paralog_clusters1 b/t/data/split_groups/paralog_clusters1
new file mode 100644
index 0000000..a8dc985
--- /dev/null
+++ b/t/data/split_groups/paralog_clusters1
@@ -0,0 +1,13 @@
+abc_02 def_02
+abc_03 def_03
+abc_04 def_04
+abc_05 def_05 abc_12 def_12
+abc_06 def_06
+abc_07 def_07
+abc_08 def_08
+abc_09 def_09
+abc_10 def_10
+abc_11 def_11
+abc_13 def_13
+abc_14 def_14
+abc_15 def_15
\ No newline at end of file
diff --git a/t/data/split_groups/paralog_clusters2 b/t/data/split_groups/paralog_clusters2
new file mode 100644
index 0000000..256f184
--- /dev/null
+++ b/t/data/split_groups/paralog_clusters2
@@ -0,0 +1,11 @@
+abc_02 def_03
+abc_03 def_04
+abc_05 def_05 abc_12 def_12
+abc_06 def_06
+abc_07 def_07
+abc_08 def_08
+abc_09 def_09
+abc_10 def_10
+abc_13 def_13
+abc_14 def_14
+abc_15 def_15
\ No newline at end of file
diff --git a/t/data/split_groups/paralog_clusters3 b/t/data/split_groups/paralog_clusters3
new file mode 100644
index 0000000..93a44e3
--- /dev/null
+++ b/t/data/split_groups/paralog_clusters3
@@ -0,0 +1,13 @@
+abc_02 def_02
+abc_03 def_03
+abc_04 def_04
+abc_05 def_05 abc_12 def_12 abc_20
+abc_06 def_06
+abc_07 def_07
+abc_08 def_08
+abc_09 def_09
+abc_10 def_10
+abc_11 def_11
+abc_13 def_13
+abc_14 def_14
+abc_15 def_15
\ No newline at end of file
diff --git a/t/data/split_groups/paralog_clusters4 b/t/data/split_groups/paralog_clusters4
new file mode 100644
index 0000000..9693ce7
--- /dev/null
+++ b/t/data/split_groups/paralog_clusters4
@@ -0,0 +1,14 @@
+abc_02 def_02
+abc_03 def_03
+abc_04 def_04
+abc_05 def_05 ghi_05 abc_12 def_12 abc_20 abc_13 def_14 def_25 ghi_23
+abc_06 def_06 ghi_06
+abc_07 def_07 ghi_07
+abc_08 def_08
+abc_09 def_09
+abc_10 def_10
+abc_11 def_11
+abc_14 def_13
+abc_15 def_15
+abc_22 def_22 ghi_22
+abc_23 def_23 ghi_23
\ No newline at end of file
diff --git a/t/data/split_groups/paralog_exp_clusters1 b/t/data/split_groups/paralog_exp_clusters1
new file mode 100644
index 0000000..511036d
--- /dev/null
+++ b/t/data/split_groups/paralog_exp_clusters1
@@ -0,0 +1,14 @@
+abc_02 def_02
+abc_03 def_03
+abc_04 def_04
+abc_05 def_05
+abc_12 def_12
+abc_06 def_06
+abc_07 def_07
+abc_08 def_08
+abc_09 def_09
+abc_10 def_10
+abc_11 def_11
+abc_13 def_13
+abc_14 def_14
+abc_15 def_15
diff --git a/t/data/split_groups/paralog_exp_clusters2 b/t/data/split_groups/paralog_exp_clusters2
new file mode 100644
index 0000000..767d19b
--- /dev/null
+++ b/t/data/split_groups/paralog_exp_clusters2
@@ -0,0 +1,12 @@
+abc_02 def_03
+abc_03 def_04
+abc_05 def_05
+abc_12 def_12
+abc_06 def_06
+abc_07 def_07
+abc_08 def_08
+abc_09 def_09
+abc_10 def_10
+abc_13 def_13
+abc_14 def_14
+abc_15 def_15
diff --git a/t/data/split_groups/paralog_exp_clusters3 b/t/data/split_groups/paralog_exp_clusters3
new file mode 100644
index 0000000..009a6f0
--- /dev/null
+++ b/t/data/split_groups/paralog_exp_clusters3
@@ -0,0 +1,15 @@
+abc_02 def_02
+abc_03 def_03
+abc_04 def_04
+abc_05 def_05
+abc_12 def_12
+abc_20
+abc_06 def_06
+abc_07 def_07
+abc_08 def_08
+abc_09 def_09
+abc_10 def_10
+abc_11 def_11
+abc_13 def_13
+abc_14 def_14
+abc_15 def_15
diff --git a/t/data/split_groups/paralog_exp_clusters4 b/t/data/split_groups/paralog_exp_clusters4
new file mode 100644
index 0000000..ed93be4
--- /dev/null
+++ b/t/data/split_groups/paralog_exp_clusters4
@@ -0,0 +1,17 @@
+abc_02 def_02
+abc_03 def_03
+abc_04 def_04
+abc_05 def_05 ghi_05
+abc_12 def_12
+abc_20 def_25 ghi_23
+abc_13 def_14
+abc_06 def_06 ghi_06
+abc_07 def_07 ghi_07
+abc_08 def_08
+abc_09 def_09
+abc_10 def_10
+abc_11 def_11
+abc_14 def_13
+abc_15 def_15
+abc_22 def_22 ghi_22
+abc_23 def_23 ghi_23
diff --git a/t/data/split_groups/paralogs1.fa b/t/data/split_groups/paralogs1.fa
new file mode 100644
index 0000000..e098cb0
--- /dev/null
+++ b/t/data/split_groups/paralogs1.fa
@@ -0,0 +1,50 @@
+>abc_01
+AAAAAAAAAAAAAAAAAAA
+>abc_02
+AAAAAAAAAAAAAAAAAAA
+>abc_03
+AAAAAAAAAAAAAAAAAAA
+>abc_04
+AAAAAAAAAAAAAAAAAAA
+>abc_05
+AAAAAAAAAAAAAAAAAAA
+>abc_06
+AAAAAAAAAAAAAAAAAAA
+>abc_07
+AAAAAAAAAAAAAAAAAAA
+>abc_08
+AAAAAAAAAAAAAAAAAAA
+>abc_09
+AAAAAAAAAAAAAAAAAAA
+>abc_10
+AAAAAAAAAAAAAAAAAAA
+>abc_11
+AAAAAAAAAAAAAAAAAAA
+>abc_12
+AAAAAAAAAAAAAAAAAAA
+>abc_13
+AAAAAAAAAAAAAAAAAAA
+>abc_14
+AAAAAAAAAAAAAAAAAAA
+>abc_15
+AAAAAAAAAAAAAAAAAAA
+>abc_16
+AAAAAAAAAAAAAAAAAAA
+>abc_17
+AAAAAAAAAAAAAAAAAAA
+>abc_18
+AAAAAAAAAAAAAAAAAAA
+>abc_19
+AAAAAAAAAAAAAAAAAAA
+>abc_20
+AAAAAAAAAAAAAAAAAAA
+>abc_21
+AAAAAAAAAAAAAAAAAAA
+>abc_22
+AAAAAAAAAAAAAAAAAAA
+>abc_23
+AAAAAAAAAAAAAAAAAAA
+>abc_24
+AAAAAAAAAAAAAAAAAAA
+>abc_25
+AAAAAAAAAAAAAAAAAAA
\ No newline at end of file
diff --git a/t/data/split_groups/paralogs2.fa b/t/data/split_groups/paralogs2.fa
new file mode 100644
index 0000000..62c3182
--- /dev/null
+++ b/t/data/split_groups/paralogs2.fa
@@ -0,0 +1,50 @@
+>def_01
+AAAAAAAAAAAAAAAAAAA
+>def_02
+AAAAAAAAAAAAAAAAAAA
+>def_03
+AAAAAAAAAAAAAAAAAAA
+>def_04
+AAAAAAAAAAAAAAAAAAA
+>def_05
+AAAAAAAAAAAAAAAAAAA
+>def_06
+AAAAAAAAAAAAAAAAAAA
+>def_07
+AAAAAAAAAAAAAAAAAAA
+>def_08
+AAAAAAAAAAAAAAAAAAA
+>def_09
+AAAAAAAAAAAAAAAAAAA
+>def_10
+AAAAAAAAAAAAAAAAAAA
+>def_11
+AAAAAAAAAAAAAAAAAAA
+>def_12
+AAAAAAAAAAAAAAAAAAA
+>def_13
+AAAAAAAAAAAAAAAAAAA
+>def_14
+AAAAAAAAAAAAAAAAAAA
+>def_15
+AAAAAAAAAAAAAAAAAAA
+>def_16
+AAAAAAAAAAAAAAAAAAA
+>def_17
+AAAAAAAAAAAAAAAAAAA
+>def_18
+AAAAAAAAAAAAAAAAAAA
+>def_19
+AAAAAAAAAAAAAAAAAAA
+>def_20
+AAAAAAAAAAAAAAAAAAA
+>def_21
+AAAAAAAAAAAAAAAAAAA
+>def_22
+AAAAAAAAAAAAAAAAAAA
+>def_23
+AAAAAAAAAAAAAAAAAAA
+>def_24
+AAAAAAAAAAAAAAAAAAA
+>def_25
+AAAAAAAAAAAAAAAAAAA
\ No newline at end of file
diff --git a/t/data/split_groups/paralogs3.fa b/t/data/split_groups/paralogs3.fa
new file mode 100644
index 0000000..d5dd3c6
--- /dev/null
+++ b/t/data/split_groups/paralogs3.fa
@@ -0,0 +1,50 @@
+>ghi_01
+AAAAAAAAAAAAAAAAAAA
+>ghi_02
+AAAAAAAAAAAAAAAAAAA
+>ghi_03
+AAAAAAAAAAAAAAAAAAA
+>ghi_04
+AAAAAAAAAAAAAAAAAAA
+>ghi_05
+AAAAAAAAAAAAAAAAAAA
+>ghi_06
+AAAAAAAAAAAAAAAAAAA
+>ghi_07
+AAAAAAAAAAAAAAAAAAA
+>ghi_08
+AAAAAAAAAAAAAAAAAAA
+>ghi_09
+AAAAAAAAAAAAAAAAAAA
+>ghi_10
+AAAAAAAAAAAAAAAAAAA
+>ghi_11
+AAAAAAAAAAAAAAAAAAA
+>ghi_12
+AAAAAAAAAAAAAAAAAAA
+>ghi_13
+AAAAAAAAAAAAAAAAAAA
+>ghi_14
+AAAAAAAAAAAAAAAAAAA
+>ghi_15
+AAAAAAAAAAAAAAAAAAA
+>ghi_16
+AAAAAAAAAAAAAAAAAAA
+>ghi_17
+AAAAAAAAAAAAAAAAAAA
+>ghi_18
+AAAAAAAAAAAAAAAAAAA
+>ghi_19
+AAAAAAAAAAAAAAAAAAA
+>ghi_20
+AAAAAAAAAAAAAAAAAAA
+>ghi_21
+AAAAAAAAAAAAAAAAAAA
+>ghi_22
+AAAAAAAAAAAAAAAAAAA
+>ghi_23
+AAAAAAAAAAAAAAAAAAA
+>ghi_24
+AAAAAAAAAAAAAAAAAAA
+>ghi_25
+AAAAAAAAAAAAAAAAAAA
\ No newline at end of file
diff --git a/t/data/split_pan_genome_sequences/argF.fa b/t/data/split_pan_genome_sequences/argF.fa
new file mode 100644
index 0000000..fc60aab
--- /dev/null
+++ b/t/data/split_pan_genome_sequences/argF.fa
@@ -0,0 +1,36 @@
+>1_3
+ATGAAAAATTTACGAAACAGAAGTTTTTTAACTTTATTAGACTTTTCACGACAAGAGGTA
+GAATTCTTATTAACACTCTCCGAGGATTTAAAACGTGCTAAATATATTGGCACTGAAAAG
+CCTATGTTAAAAAATAAAAATATTGCACTGTTATTTGAAAAAGATTCTACAAGAACGCGA
+TGTGCATTTGAAGTTGCAGCGCATGATCAAGGTGCAAATGTAACTTATTTAGGCCCAACT
+GGATCACAAATGGGTAAAAAAGAAACAACTAAAGATACTGCACGTGTGCTTGGTGGAATG
+TATGATGGCATTGAATACCGTGGTTTTTCACAAAGAACAGTAGAAACTTTAGCTGAAAAT
+TCAGGCGTACCAGTGTGGAATGGTTTAACTGATGAAGATCATCCTACTCAAGTTCTTGCT
+GATTTCTTAACAGCAAAAGAAGTCTTAAAAAAAGATTATGCAGATATTAACTTTACATAT
+GTTGGAGATGGTCGTAATAACGTTGCAAATGCATTAATGCAAGGTGCTGCCATTATGGGT
+ATGAACTTCCATTTAGTTTGTCCAAAAGAATTAAATCCAACAGATGAATTATTAAATCGC
+TGTAAAAATATTGCCGCTGAAAATGGTGGCAACATATTAATCACAGATGATATTGACCAA
+GGTGTAAAAGGTTCGGATGTAATTTACACTGATGTTTGGGTATCAATGGGTGAACCTGAT
+GAAGTATGGAAAGAACGACTTGAATTATTGAAACCATATCAAGTAAATAAAGAAATGATG
+GATAAAACTGGTAATCCAAATGTTATTTTTGAGCATTGCTTACCATCTTTCCATAATGCT
+GATACGAAAATTGGTCAACAAATTTTTGAAAAATATGGTATTCGAGAAATGGAAGTTACA
+GATGAAGTATTCGAAAGTAAAGCTTCAGTTGTATTCCAAGAAGCTGAGAACAGAATGCAT
+ACAATCAAAGCAGTCATGGTTGCTACATTGGGTGAATTTTAA
+>3_3
+ATGAAAAATTTACGAAACAGAAGTTTTTTAACTTTATTAGACTTTTCACGACAAGAGGTA
+GAATTCTTATTAACACTCTCCGAGGATTTAAAACGTGCTAAATATATTGGCACTGAAAAG
+CCTATGTTAAAAAATAAAAATATTGCACTGTTATTTGAAAAAGATTCTACAAGAACGCGA
+TGTGCATTTGAAGTTGCAGCGCATGATCAAGGTGCAAATGTAACTTATTTAGGCCCAACT
+GGATCACAAATGGGTAAAAAAGAAACAACTAAAGATACTGCACGTGTGCTTGGTGGAATG
+TATGATGGCATTGAATACCGTGGTTTTTCACAAAGAACAGTAGAAACTTTAGCTGAAAAT
+TCAGGCGTACCAGTGTGGAATGGTTTAACTGATGAAGATCATCCTACTCAAGTTCTTGCT
+GATTTCTTAACAGCAAAAGAAGTCTTAAAAAAAGATTATGCAGATATTAACTTTACATAT
+GTTGGAGATGGTCGTAATAACGTTGCAAATGCATTAATGCAAGGTGCTGCCATTATGGGT
+ATGAACTTCCATTTAGTTTGTCCAAAAGAATTAAATCCAACAGATGAATTATTAAATCGC
+TGTAAAAATATTGCCGCTGAAAATGGTGGCAACATATTAATCACAGATGATATTGACCAA
+GGTGTAAAAGGTTCGGATGTAATTTACACTGATGTTTGGGTATCAATGGGTGAACCTGAT
+GAAGTATGGAAAGAACGACTTGAATTATTGAAACCATATCAAGTAAATAAAGAAATGATG
+GATAAAACTGGTAATCCAAATGTTATTTTTGAGCATTGCTTACCATCTTTCCATAATGCT
+GATACGAAAATTGGTCAACAAATTTTTGAAAAATATGGTATTCGAGAAATGGAAGTTACA
+GATGAAGTATTCGAAAGTAAAGCTTCAGTTGTATTCCAAGAAGCTGAGAACAGAATGCAT
+ACAATCAAAGCAGTCATGGTTGCTACATTGGGTGAATTTTAA
diff --git a/t/data/split_pan_genome_sequences/different.fa b/t/data/split_pan_genome_sequences/different.fa
new file mode 100644
index 0000000..eb960ac
--- /dev/null
+++ b/t/data/split_pan_genome_sequences/different.fa
@@ -0,0 +1,38 @@
+>1_1
+ATGAAAACACGTATAGTCAGCTCAGTAACAACAACACTATTGCTAGGTTCCATATTAATG
+AATCCTGTCGCTAATGCCGCAGATTCTGATATTAATATTAAAACCGGTACTACAGATATT
+GGAAGCAATACTACAGTAAAAACAGGTGATTTAGTCACTTATGATAAAGAAAATGGCATG
+CACAAAAAAGTATTTTATAGTTTTATCGATGATAAAAATCACAATAAAAAACTGCTAGTT
+ATTAGAACGAAAGGTACCATTGCTGGTCAATATAGAGTTTATAGCGAAGAAGGTGCTAAC
+AAAAGTGGTTTAGCCTGGCCTTCAGCCTTTAAGGTACAGTTGCAACTACCTGATAATGAA
+GTAGCTCAAATATCTGATTACTATCCAAGAAATTCGATTGATACAAAAGAGTATATGAGT
+ACTTTAACTTATGGATTCAACGGTAATGTTACTGGTGATGATACAGGAAAAATTGGCGGC
+CTTATTGGTGCAAATGTTTCGATTGGTCATACACTGAAATATGTTCAACCTGATTTCAAA
+ACAATTTTAGAGAGCCCAACTGATAAAAAAGTAGGCTGGAAAGTGATATTTAACAATATG
+GTGAATCAAAATTGGGGACCATATGATAGAGATTCTTGGAACCCGGTATATGGCAATCAA
+CTTTTCATGAAAACTAGAAATGGTTCTATGAAAGCAGCAGAGAACTTCCTTGATCCTAAC
+AAAGCAAGTTCTCTATTATCTTCAGGGTTTTCACCAGACTTCGCTACAGTTATTACTATG
+GATAGAAAAGCATCCAAACAACAAACAAATATAGATGTAATATACGAACGAGTTCGTGAT
+GACTACCAATTGCATTGGACTTCAACAAATTGGAAAGGTACCAATACTAAAGATAAATGG
+ACAGATCGTTCTTCAGAAAGATATAAAATCGATTGGGAAAAAGAAGAAATGACAAATTAA
+>1_6
+ATGACTGGACTAGCAGAAGCAATCGCAAATACTGTGCAAGCTGCACAACAACATGATAGT
+GTGAAATTAGGCACAAGTATCGTAGACATCGTTGCTAACGGTGTGGGTTTACTAGGTAAA
+TTATTTGGATTCTAA
+>2_7
+ATGACTGGACTAGCAGAAGCAATCGCAAATACTGTGCAAGCTGCACAACAACATGATAGT
+GTGAAATTAGGCACAAGTATCGTAGACATCGTTGCTAACGGTGTGGGTTTACTAGGTAAA
+TTATTTGGATTCTAA
+>3_5
+TTGGGATATAAAAATATTTTGATAGACTTTGATGATACAATTGTTGATTTTTATGATGCA
+GAAGAATGGGCGTTTCACTATATGGCGAATGTTTTTAATCATAAAGCAACAAAGGATGAT
+TTTTTAACATTTAAAAAAATCAATCACCAACATTGGGAAGCTTTTCAACAAAATAAATTA
+ACGAAGTCTGAAGTATTATCAGAACGATTTGTGAATTACTTCAAACATCATCAAATGGAA
+GTTGATGGGCATCGTGCAGATGTGTTATTTAGAAATGGATTAGCAGAAGCTAAAGTTAAA
+TACTTTGATCAAACATTAGAAACAATTGTCGAATTATCGAAAAGACATGATTTATATATT
+GTTACTAATGGTGTAACCGAAACGCAAAAGAGAAGGTTAAATCAGACGCCGTTGCATAAA
+TATATTAAAAAGATATTTATATCTGAGGAAACAGGATATCAAAAACCTAATCCGGAATTT
+TTTAATTATGTTTTTAATGATATTGGTGAGGATGAAAGACAGCACTCGATTATAGTTGGA
+GATTCTTTAACATCTGACATTCTAGGTGGAATCAATGCGGGTATAGCTACTTGCTGGTTT
+AATTTTAGAGGATTTGATCATAATCCAGGAATTATACCTGATTATGAAATTAATTCATGG
+AAACAACTAAATGATATTGTACGTTAA
diff --git a/t/data/split_pan_genome_sequences/hly.fa b/t/data/split_pan_genome_sequences/hly.fa
new file mode 100644
index 0000000..42a7fdf
--- /dev/null
+++ b/t/data/split_pan_genome_sequences/hly.fa
@@ -0,0 +1,34 @@
+>2_1
+ATGAAAACACGTATAGTCAGCTCAGTAACAACAACACTATTGCTAGGTTCCATATTAATG
+AATCCTGTCGCTAATGCCGCAGATTCTGATATTAATATTAAAACCGGTACTACAGATATT
+GGAAGCAATACTACAGTAAAAACAGGTGATTTAGTCACTTATGATAAAGAAAATGGCATG
+CACAAAAAAGTATTTTATAGTTTTATCGATGATAAAAATCACAATAAAAAACTGCTAGTT
+ATTAGAACGAAAGGTACCATTGCTGGTCAATATAGAGTTTATAGCGAAGAAGGTGCTAAC
+AAAAGTGGTTTAGCCTGGCCTTCAGCCTTTAAGGTACAGTTGCAACTACCTGATAATGAA
+GTAGCTCAAATATCTGATTACTATCCAAGAAATTCGATTGATACAAAAGAGTATATGAGT
+ACTTTAACTTATGGATTCAACGGTAATGTTACTGGTGATGATACAGGAAAAATTGGCGGC
+CTTATTGGTGCAAATGTTTCGATTGGTCATACACTGAAATATGTTCAACCTGATTTCAAA
+ACAATTTTAGAGAGCCCAACTGATAAAAAAGTAGGCTGGAAAGTGATATTTAACAATATG
+GTGAATCAAAATTGGGGACCATATGATAGAGATTCTTGGAACCCGGTATATGGCAATCAA
+CTTTTCATGAAAACTAGAAATGGTTCTATGAAAGCAGCAGAGAACTTCCTTGATCCTAAC
+AAAGCAAGTTCTCTATTATCTTCAGGGTTTTCACCAGACTTCGCTACAGTTATTACTATG
+GATAGAAAAGCATCCAAACAACAAACAAATATAGATGTAATATACGAACGAGTTCGTGAT
+GACTACCAATTGCATTGGACTTCAACAAATTGGAAAGGTACCAATACTAAAGATAAATGG
+ACAGATCGTTCTTCAGAAAGATATAAAATCGATTGGGAAAAAGAAGAAATGACAAATTAA
+>3_1
+ATGAAAACACGTATAGTCAGCTCAGTAACAACAACACTATTGCTAGGTTCCATATTAATG
+AATCCTGTCGCTAATGCCGCAGATTCTGATATTAATATTAAAACCGGTACTACAGATATT
+GGAAGCAATACTACAGTAAAAACAGGTGATTTAGTCACTTATGATAAAGAAAATGGCATG
+CACAAAAAAGTATTTTATAGTTTTATCGATGATAAAAATCACAATAAAAAACTGCTAGTT
+ATTAGAACGAAAGGTACCATTGCTGGTCAATATAGAGTTTATAGCGAAGAAGGTGCTAAC
+AAAAGTGGTTTAGCCTGGCCTTCAGCCTTTAAGGTACAGTTGCAACTACCTGATAATGAA
+GTAGCTCAAATATCTGATTACTATCCAAGAAATTCGATTGATACAAAAGAGTATATGAGT
+ACTTTAACTTATGGATTCAACGGTAATGTTACTGGTGATGATACAGGAAAAATTGGCGGC
+CTTATTGGTGCAAATGTTTCGATTGGTCATACACTGAAATATGTTCAACCTGATTTCAAA
+ACAATTTTAGAGAGCCCAACTGATAAAAAAGTAGGCTGGAAAGTGATATTTAACAATATG
+GTGAATCAAAATTGGGGACCATATGATAGAGATTCTTGGAACCCGGTATATGGCAATCAA
+CTTTTCATGAAAACTAGAAATGGTTCTATGAAAGCAGCAGAGAACTTCCTTGATCCTAAC
+AAAGCAAGTTCTCTATTATCTTCAGGGTTTTCACCAGACTTCGCTACAGTTATTACTATG
+GATAGAAAAGCATCCAAACAACAAACAAATATAGATGTAATATACGAACGAGTTCGTGAT
+GACTACCAATTGCATTGGACTTCAACAAATTGGAAAGGTACCAATACTAAAGATAAATGG
+ACAGATCGTTCTTCAGAAAGATATAAAATCGATTGGGAAAAAGAAGAAATGACAAATTAA
diff --git a/t/data/split_pan_genome_sequences/reannotated_groups_file b/t/data/split_pan_genome_sequences/reannotated_groups_file
new file mode 100644
index 0000000..9cbf9e6
--- /dev/null
+++ b/t/data/split_pan_genome_sequences/reannotated_groups_file
@@ -0,0 +1,4 @@
+different: 1_1 2_4 3_4 3_5 1_6 2_7
+speH: 1_2 2_2
+hly: 2_1 3_1
+argF: 1_3 3_3
diff --git a/t/data/split_pan_genome_sequences/speH.fa b/t/data/split_pan_genome_sequences/speH.fa
new file mode 100644
index 0000000..2e8dc9d
--- /dev/null
+++ b/t/data/split_pan_genome_sequences/speH.fa
@@ -0,0 +1,28 @@
+>1_2
+ATGAACAATAACATCACGAAAAAAATTATTTTATCAACAACATTGTTACTATTAGGTACA
+GCATTTACACAATTTCCTAATACACCTATCAATTCTTCATCTGAAGCGAAAGCTTATTAT
+ATAAATCAAAACGAAACTAACGTTAATGAGTTAACTAAATATTACTCGCAAAAATATTTA
+ACCTTCTCTAACAGTACGTTATGGCAAAAAGATAACGGTACGATTCATGCAACGTTGTTA
+CAGTTTTCTTGGTATAGTCATATTCAAGTTTATGGACCTGAAAGTTGGGGCAATATCAAC
+CAATTAAGAAATAAAAGCGTTGATATTTTTGGCATAAAAGACCAAGAAACCATTGATTCT
+TTTGCATTATCTCAAGAAACGTTTACTGGTGGTGTTACTCCTGCAGCAACATCTAACGAT
+AAACACTATAAACTGAATGTAACATATAAAGATAAAGCAGAAACGTTTACTGGCGGATTT
+CCAGTTTATGAAGGCAATAAGCCTGTTTTAACTTTAAAAGAATTAGATTTTCGTATTCGT
+CAAACATTAATTAAAAGTAAAAAATTATATAATAATTCTTATAATAAAGGACAAATTAAA
+ATAACAGGTACAGACAATAACTACACAATAGATTTAAGTAAAAGGTTGCCATCAACTGAT
+GCAAATAGATATGTTAAAAAACCTCAAAATGCAAAAATTGAAGTTATCCTCGAAAAATCA
+AACTAA
+>2_2
+ATGAACAATAACATCACGAAAAAAATTATTTTATCAACAACATTGTTACTATTAGGTACA
+GCATTTACACAATTTCCTAATACACCTATCAATTCTTCATCTGAAGCGAAAGCTTATTAT
+ATAAATCAAAACGAAACTAACGTTAATGAGTTAACTAAATATTACTCGCAAAAATATTTA
+ACCTTCTCTAACAGTACGTTATGGCAAAAAGATAACGGTACGATTCATGCAACGTTGTTA
+CAGTTTTCTTGGTATAGTCATATTCAAGTTTATGGACCTGAAAGTTGGGGCAATATCAAC
+CAATTAAGAAATAAAAGCGTTGATATTTTTGGCATAAAAGACCAAGAAACCATTGATTCT
+TTTGCATTATCTCAAGAAACGTTTACTGGTGGTGTTACTCCTGCAGCAACATCTAACGAT
+AAACACTATAAACTGAATGTAACATATAAAGATAAAGCAGAAACGTTTACTGGCGGATTT
+CCAGTTTATGAAGGCAATAAGCCTGTTTTAACTTTAAAAGAATTAGATTTTCGTATTCGT
+CAAACATTAATTAAAAGTAAAAAATTATATAATAATTCTTATAATAAAGGACAAATTAAA
+ATAACAGGTACAGACAATAACTACACAATAGATTTAAGTAAAAGGTTGCCATCAACTGAT
+GCAAATAGATATGTTAAAAAACCTCAAAATGCAAAAATTGAAGTTATCCTCGAAAAATCA
+AACTAA
diff --git a/t/data/uneven_sequences.fa b/t/data/uneven_sequences.fa
new file mode 100644
index 0000000..ea59566
--- /dev/null
+++ b/t/data/uneven_sequences.fa
@@ -0,0 +1,18 @@
+>1
+a
+>2
+aa
+>3
+aaa
+>4
+aaaa
+>5
+aaaaa
+>6
+aaaaaa
+>7
+aaaaaaa
+>8
+aaaaaaaa
+>9
+aaaaaaaaa
\ No newline at end of file
diff --git a/t/data/uneven_sequences.fa.sorted.fa b/t/data/uneven_sequences.fa.sorted.fa
new file mode 100644
index 0000000..c9f0e0c
--- /dev/null
+++ b/t/data/uneven_sequences.fa.sorted.fa
@@ -0,0 +1,18 @@
+>1
+aNN
+>2
+aaN
+>3
+aaa
+>4
+aaaaNN
+>5
+aaaaaN
+>6
+aaaaaa
+>7
+aaaaaaaNN
+>8
+aaaaaaaaN
+>9
+aaaaaaaaa
diff --git a/t/data/variable_core/gene_1.fa.aln b/t/data/variable_core/gene_1.fa.aln
new file mode 100644
index 0000000..6f25d27
--- /dev/null
+++ b/t/data/variable_core/gene_1.fa.aln
@@ -0,0 +1,10 @@
+>111_00001
+AAAA
+>222_00001
+AAAA
+>333_00001
+AAAA
+>444_00001
+AAAA
+>555_00001
+AAAA
\ No newline at end of file
diff --git a/t/data/variable_core/gene_2.fa.aln b/t/data/variable_core/gene_2.fa.aln
new file mode 100644
index 0000000..0bf355e
--- /dev/null
+++ b/t/data/variable_core/gene_2.fa.aln
@@ -0,0 +1,8 @@
+>333_00002
+CCCCCCC
+>444_00002
+CCCCCCC
+>555_00002
+CCCCCCC
+>222_00002
+CCCCCCC
\ No newline at end of file
diff --git a/t/data/variable_core/gene_3.fa.aln b/t/data/variable_core/gene_3.fa.aln
new file mode 100644
index 0000000..2f7c1f3
--- /dev/null
+++ b/t/data/variable_core/gene_3.fa.aln
@@ -0,0 +1,8 @@
+>111_00003
+GG
+>333_00003
+GG
+>222_00003
+GG
+>444_00003
+GG
\ No newline at end of file
diff --git a/t/data/variable_core/gene_4.fa.aln b/t/data/variable_core/gene_4.fa.aln
new file mode 100644
index 0000000..5a62879
--- /dev/null
+++ b/t/data/variable_core/gene_4.fa.aln
@@ -0,0 +1,4 @@
+>222_00004
+TTTTT
+>444_00004
+TTTTT
\ No newline at end of file
diff --git a/t/data/variable_core/gene_5.fa.aln b/t/data/variable_core/gene_5.fa.aln
new file mode 100644
index 0000000..c2e36a0
--- /dev/null
+++ b/t/data/variable_core/gene_5.fa.aln
@@ -0,0 +1,10 @@
+>555_00005
+XXXXXXX
+>111_00005
+XXXXXXX
+>222_00005
+XXXXXXX
+>333_00005
+XXXXXXX
+>444_00005
+XXXXXXX
\ No newline at end of file
diff --git a/t/dummy_blastp b/t/dummy_blastp
new file mode 100755
index 0000000..1e374d4
--- /dev/null
+++ b/t/dummy_blastp
@@ -0,0 +1,3 @@
+#!/usr/bin/env perl
+system("touch results.out");
+1;
\ No newline at end of file
diff --git a/t/dummy_cd-hit b/t/dummy_cd-hit
new file mode 100755
index 0000000..c3e21e3
--- /dev/null
+++ b/t/dummy_cd-hit
@@ -0,0 +1,5 @@
+#!/usr/bin/env perl
+system("touch output");
+system("touch output.clstr");
+system("touch output.bak.clstr");
+1;
\ No newline at end of file
diff --git a/t/dummy_makeblastdb b/t/dummy_makeblastdb
new file mode 100755
index 0000000..0ccbc2a
--- /dev/null
+++ b/t/dummy_makeblastdb
@@ -0,0 +1,5 @@
+#!/usr/bin/env perl
+system("touch output_contigs.phr");
+system("touch output_contigs.pin");
+system("touch output_contigs.psq");
+1;
\ No newline at end of file
diff --git a/t/lib/TestHelper.pm b/t/lib/TestHelper.pm
new file mode 100644
index 0000000..aae17f1
--- /dev/null
+++ b/t/lib/TestHelper.pm
@@ -0,0 +1,323 @@
+package TestHelper;
+use Moose::Role;
+use Test::Most;
+use Data::Dumper;
+use File::Slurper qw(read_lines read_text);
+use Test::Files;
+use Test::Output;
+
+$ENV{PATH} .= ":./bin";
+
+sub compare_files {
+ my ( $actual_file, $expected_file, $comment ) = @_;
+ my @actual_lines = sort( read_lines($actual_file) );
+ my @expected_lines = sort( read_lines($expected_file) );
+ is_deeply( \@actual_lines, \@expected_lines, $comment );
+}
+
+sub compare_groups_files {
+ my ( $actual_file, $expected_file, $comment ) = @_;
+ my @actual_lines = sort( read_lines($actual_file) );
+ my @expected_lines = sort( read_lines($expected_file) );
+
+ my @actual_sorted_lines;
+ for my $line (@actual_lines) {
+ my @line_details = split( / /, $line );
+ shift @line_details;
+ my @sorted = sort(@line_details);
+ push( @actual_sorted_lines, \@sorted );
+ }
+
+ my @expected_sorted_lines;
+ for my $line (@expected_lines) {
+ my @line_details = split( / /, $line );
+ shift @line_details;
+ my @sorted = sort(@line_details);
+ push( @expected_sorted_lines, \@sorted );
+ }
+ is_deeply( \@actual_sorted_lines, \@expected_sorted_lines, $comment );
+}
+
+
+sub stdout_should_have
+{
+ my ( $script_name, $parameters, $expected ) = @_;
+ my @input_args = split( " ", $parameters );
+ open OLDERR, '>&STDERR';
+ eval("use $script_name ;");
+ my $returned_values = 0;
+ {
+ local *STDERR;
+ open STDERR, '>/dev/null' or warn "Can't open /dev/null: $!";
+ stdout_like { eval("$script_name->new(args => \\\@input_args, script_name => '$script_name')->run;"); } qr/$expected/, "got expected text $expected for $parameters";
+ close STDERR;
+ }
+ open STDERR, '>&OLDERR' or die "Can't restore stderr: $!";
+ close OLDERR or die "Can't close OLDERR: $!";
+}
+
+
+sub stdout_should_not_have
+{
+ my ( $script_name, $parameters, $expected ) = @_;
+ my @input_args = split( " ", $parameters );
+ open OLDERR, '>&STDERR';
+ eval("use $script_name ;");
+ my $returned_values = 0;
+ {
+ local *STDERR;
+ open STDERR, '>/dev/null' or warn "Can't open /dev/null: $!";
+ stdout_unlike { eval("$script_name->new(args => \\\@input_args, script_name => '$script_name')->run;"); } qr/$expected/, "got expected text $expected for $parameters";
+ close STDERR;
+ }
+ open STDERR, '>&OLDERR' or die "Can't restore stderr: $!";
+ close OLDERR or die "Can't close OLDERR: $!";
+}
+
+
+
+sub stderr_should_not_have
+{
+ my ( $script_name, $parameters, $expected ) = @_;
+ my @input_args = split( " ", $parameters );
+ open OLDOUT, '>&STDOUT';
+ eval("use $script_name ;");
+ my $returned_values = 0;
+ {
+ local *STDOUT;
+ open STDOUT, '>/dev/null' or warn "Can't open /dev/null: $!";
+ stderr_unlike { eval("$script_name->new(args => \\\@input_args, script_name => '$script_name')->run;"); } qr/$expected/, "got expected text $expected for $parameters";
+ close STDOUT;
+ }
+ open STDOUT, '>&OLDOUT' or die "Can't restore stdout: $!";
+ close OLDOUT or die "Can't close OLDOUT: $!";
+}
+
+sub stderr_should_have
+{
+ my ( $script_name, $parameters, $expected ) = @_;
+ my @input_args = split( " ", $parameters );
+ open OLDOUT, '>&STDOUT';
+ eval("use $script_name ;");
+ my $returned_values = 0;
+ {
+ local *STDOUT;
+ open STDOUT, '>/dev/null' or warn "Can't open /dev/null: $!";
+ stderr_like { eval("$script_name->new(args => \\\@input_args, script_name => '$script_name')->run;"); } qr/$expected/, "got expected text $expected for $parameters";
+ close STDOUT;
+ }
+ open STDOUT, '>&OLDOUT' or die "Can't restore stdout: $!";
+ close OLDOUT or die "Can't close OLDOUT: $!";
+}
+
+
+sub mock_execute_script_and_check_output {
+ my ( $script_name, $scripts_and_expected_files, $columns_to_exclude ) = @_;
+
+ system('touch empty_file');
+
+ open OLDOUT, '>&STDOUT';
+ open OLDERR, '>&STDERR';
+ eval("use $script_name ;");
+ my $returned_values = 0;
+ {
+ local *STDOUT;
+ open STDOUT, '>/dev/null' or warn "Can't open /dev/null: $!";
+ local *STDERR;
+ open STDERR, '>/dev/null' or warn "Can't open /dev/null: $!";
+
+ for my $script_parameters ( sort keys %$scripts_and_expected_files ) {
+ my $full_script = $script_parameters;
+ my @input_args = split( " ", $full_script );
+
+ my $cmd = "$script_name->new(args => \\\@input_args, script_name => '$script_name')->run;";
+ eval($cmd);
+ warn $@ if $@;
+
+ my $actual_output_file_name = $scripts_and_expected_files->{$script_parameters}->[0];
+ my $expected_output_file_name = $scripts_and_expected_files->{$script_parameters}->[1];
+ ok( -e $actual_output_file_name, "Actual output file exists $actual_output_file_name $script_parameters" );
+ if ( defined($columns_to_exclude) ) {
+ is(
+ _exclude_variable_columns_from_spreadsheet( $actual_output_file_name, $columns_to_exclude ),
+ _exclude_variable_columns_from_spreadsheet( $expected_output_file_name, $columns_to_exclude ),
+ 'Actual and expected match output excluding variable columns'
+ );
+ }
+ else {
+ compare_ok( $actual_output_file_name, $expected_output_file_name,
+ "Actual and expected output match for '$script_parameters'" );
+
+ }
+ unlink($actual_output_file_name);
+ }
+ close STDOUT;
+ close STDERR;
+ }
+
+ # Restore stdout.
+ open STDOUT, '>&OLDOUT' or die "Can't restore stdout: $!";
+ open STDERR, '>&OLDERR' or die "Can't restore stderr: $!";
+
+ # Avoid leaks by closing the independent copies.
+ close OLDOUT or die "Can't close OLDOUT: $!";
+ close OLDERR or die "Can't close OLDERR: $!";
+ unlink('empty_file');
+}
+
+sub mock_execute_script_and_check_output_sorted_groups {
+ my ( $script_name, $scripts_and_expected_files, $columns_to_exclude ) = @_;
+
+ system('touch empty_file');
+
+ open OLDOUT, '>&STDOUT';
+ open OLDERR, '>&STDERR';
+ eval("use $script_name ;");
+ my $returned_values = 0;
+ {
+ local *STDOUT;
+ open STDOUT, '>/dev/null' or warn "Can't open /dev/null: $!";
+ local *STDERR;
+ open STDERR, '>/dev/null' or warn "Can't open /dev/null: $!";
+
+ for my $script_parameters ( sort keys %$scripts_and_expected_files ) {
+ my $full_script = $script_parameters;
+ my @input_args = split( " ", $full_script );
+
+ my $cmd = "$script_name->new(args => \\\@input_args, script_name => '$script_name')->run;";
+ eval($cmd);
+ warn $@ if $@;
+
+ my $actual_output_file_name = $scripts_and_expected_files->{$script_parameters}->[0];
+
+ my $expected_output_file_name = $scripts_and_expected_files->{$script_parameters}->[1];
+ ok( -e $actual_output_file_name, "Actual output file exists $actual_output_file_name $script_parameters" );
+ if ( defined($columns_to_exclude) ) {
+ my @actual_content_sorted =
+ sort( split( /\n/, _exclude_variable_columns_from_spreadsheet( $actual_output_file_name, $columns_to_exclude ) ) );
+ my @expected_content_sorted =
+ sort( split( /\n/, _exclude_variable_columns_from_spreadsheet( $expected_output_file_name, $columns_to_exclude ) ) );
+ is_deeply( \@actual_content_sorted, \@expected_content_sorted,
+ 'Actual and expected match output excluding variable columns' );
+ }
+ else {
+ compare_groups_files( $actual_output_file_name, $expected_output_file_name,
+ "Actual and expected sorted output match for '$script_parameters'" );
+ }
+ unlink($actual_output_file_name);
+ }
+ close STDOUT;
+ close STDERR;
+ }
+
+ # Restore stdout.
+ open STDOUT, '>&OLDOUT' or die "Can't restore stdout: $!";
+ open STDERR, '>&OLDERR' or die "Can't restore stderr: $!";
+
+ # Avoid leaks by closing the independent copies.
+ close OLDOUT or die "Can't close OLDOUT: $!";
+ close OLDERR or die "Can't close OLDERR: $!";
+ unlink('empty_file');
+}
+
+sub mock_execute_script_and_check_output_sorted {
+ my ( $script_name, $scripts_and_expected_files, $columns_to_exclude ) = @_;
+
+ system('touch empty_file');
+
+ open OLDOUT, '>&STDOUT';
+ open OLDERR, '>&STDERR';
+ eval("use $script_name ;");
+ my $returned_values = 0;
+ {
+ local *STDOUT;
+ open STDOUT, '>/dev/null' or warn "Can't open /dev/null: $!";
+ local *STDERR;
+ open STDERR, '>/dev/null' or warn "Can't open /dev/null: $!";
+
+ for my $script_parameters ( sort keys %$scripts_and_expected_files ) {
+ my $full_script = $script_parameters;
+ my @input_args = split( " ", $full_script );
+
+ my $cmd = "$script_name->new(args => \\\@input_args, script_name => '$script_name')->run;";
+ eval($cmd);
+ warn $@ if $@;
+
+ my $actual_output_file_name = $scripts_and_expected_files->{$script_parameters}->[0];
+
+ my $expected_output_file_name = $scripts_and_expected_files->{$script_parameters}->[1];
+ ok( -e $actual_output_file_name, "Actual output file exists $actual_output_file_name $script_parameters" );
+ if ( defined($columns_to_exclude) ) {
+ my @actual_content_sorted =
+ sort( split( /\n/, _exclude_variable_columns_from_spreadsheet( $actual_output_file_name, $columns_to_exclude ) ) );
+ my @expected_content_sorted =
+ sort( split( /\n/, _exclude_variable_columns_from_spreadsheet( $expected_output_file_name, $columns_to_exclude ) ) );
+ is_deeply( \@actual_content_sorted, \@expected_content_sorted,
+ 'Actual and expected match output excluding variable columns' );
+ }
+ else {
+ compare_groups_files( $actual_output_file_name, $expected_output_file_name,
+ "Actual and expected sorted output match for '$script_parameters'" );
+ }
+ unlink($actual_output_file_name);
+ }
+ close STDOUT;
+ close STDERR;
+ }
+
+ # Restore stdout.
+ open STDOUT, '>&OLDOUT' or die "Can't restore stdout: $!";
+ open STDERR, '>&OLDERR' or die "Can't restore stderr: $!";
+
+ # Avoid leaks by closing the independent copies.
+ close OLDOUT or die "Can't close OLDOUT: $!";
+ close OLDERR or die "Can't close OLDERR: $!";
+ unlink('empty_file');
+}
+
+sub compare_tab_files_with_variable_coordinates {
+ my ( $actual_file, $expected_file ) = @_;
+ ok( -e $actual_file, 'File exists' . $actual_file );
+
+ is(
+ _filter_coordinates_from_string($actual_file),
+ _filter_coordinates_from_string($expected_file),
+ 'file contents the same for ' . $actual_file
+ );
+}
+
+sub _filter_coordinates_from_string {
+ my ($file_name) = @_;
+ my $file_contents = read_text($file_name);
+ my @lines = split( /\n/, $file_contents );
+ my $modified_file_contents = '';
+ for my $line ( sort @lines ) {
+ next if ( $line =~ /(variation|misc_feature|feature)/ );
+ $line =~ s!group_[\d]+!group_XX!gi;
+ $modified_file_contents .= $line . "\n";
+ }
+ return $modified_file_contents;
+}
+
+sub _exclude_variable_columns_from_spreadsheet {
+ my ( $file_name, $columns_to_exclude ) = @_;
+ my $file_contents = read_text($file_name);
+ my @lines = split( /\n/, $file_contents );
+ my $modified_file_contents = '';
+
+ for ( my $i = 0 ; $i < @lines ; $i++ ) {
+ my @cells = split( /,/, $lines[$i] );
+
+ for my $col_number ( @{$columns_to_exclude} ) {
+ next unless ( defined( $cells[$col_number] ) );
+ $cells[$col_number] = '';
+ }
+ $modified_file_contents .= join( ',', @cells ) . "\n";
+ }
+
+ return $modified_file_contents;
+}
+
+no Moose;
+1;
+
--
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