[Debian-med-packaging] Bug#991557: ITP: broad-catch -- design sets of primers to identify genomes

Steffen Moeller moeller at debian.org
Tue Jul 27 15:16:49 BST 2021


Package: wnpp
Severity: wishlist

Subject: ITP: broad-catch -- design sets of primers to identify genomes
Package: wnpp
Owner: Steffen Moeller <moeller at debian.org>
Severity: wishlist

* Package name    : broad-catch
  Version         : 1.4.0
  Upstream Author : Hayden Metsky <hayden at mit.edu>
* URL             : https://github.com/broadinstitute/catch
* License         : MIT
  Programming Lang: Python
  Description     : design sets of primers to identify genomes
 CATCH (Compact Aggregation of Targets for Comprehensive Hybridization)
 is a Python package for designing probe sets to use for nucleic acid
 capture of diverse sequence.
 .
  * Comprehensive coverage: CATCH accepts any collection of unaligned
    sequences — typically whole genomes of all known genetic diversity of
    one or more microbial species. It designs oligo sequences that guarantee
    coverage of this diversity, enabling rapid design of exhaustive probe
    sets for customizable targets.
  * Compact designs: CATCH can design with a specified constraint on the
    number of oligos (e.g., array size). It searches a space of probe sets,
    which may pool many species, to find an optimal design. This allows its
    designs to scale well with known genetic diversity, and also supports
    cost-effective applications.
  * Flexibility: CATCH supports applications beyond whole genome
    enrichment, such as differential identification of species. It allows
    blacklisting sequence from the design (e.g., background in microbial
    enrichment), supports customized models of hybridization, enables
    weighting the sensitivity for different species, and more.

Remark: This package is maintained by Debian Med Packaging Team at
   https://salsa.debian.org/med-team/catch


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