[Debian-med-packaging] Bug#1029719: ITP: libwfa2 -- exact gap-affine algorithm
Andreas Tille
tille at debian.org
Thu Jan 26 16:36:03 GMT 2023
Package: wnpp
Severity: wishlist
Subject: ITP: libwfa2 -- exact gap-affine algorithm
Package: wnpp
Owner: Andreas Tille <tille at debian.org>
Severity: wishlist
* Package name : libwfa2
Version : 2.3.1
Upstream Author : Santiago Marco-Sola <santiagomsola at gmail.com>
* URL : https://github.com/smarco/WFA2-lib
* License : MIT
Programming Lang: C
Description : exact gap-affine algorithm
The wavefront alignment (WFA) algorithm is an exact gap-affine algorithm
that takes advantage of homologous regions between the sequences to
accelerate the alignment process. Unlike to traditional dynamic
programming algorithms that run in quadratic time, the WFA runs in time
O(ns+s^2), proportional to the sequence length n and the alignment score
s, using O(s^2) memory (or O(s) using the ultralow/BiWFA mode).
Moreover, the WFA algorithm exhibits simple computational patterns that
the modern compilers can automatically vectorize for different
architectures without adapting the code. To intuitively illustrate why
the WFA algorithm is so interesting, look at the following figure. The
left panel shows the cells computed by a classical dynamic programming
based algorithm (like Smith-Waterman or Needleman Wunsch). In contrast,
the right panel shows the cells computed by the WFA algorithm to obtain
the same result (i.e., the optimal alignment).
Remark: This package is maintained by Debian Med Packaging Team at
https://salsa.debian.org/med-team/libwfa2
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