[R-pkg-team] Bug#1008221: ITP: r-bioc-tmixclust -- mixed-effects gene-expression time-series analysis
Steffen Moeller
moeller at debian.org
Thu Mar 24 15:10:29 GMT 2022
Package: wnpp
Severity: wishlist
Subject: ITP: r-bioc-tmixclust -- mixed-effects gene-expression time-series analysis
Package: wnpp
Owner: Steffen Moeller <moeller at debian.org>
Severity: wishlist
* Package name : r-bioc-tmixclust
Version : 1.16.0
Upstream Author : Monica Golumbeanu <golumbeanu.monica at gmail.com>
* URL : https://bioconductor.org/packages/TMixClust/
* License : GPL-2+
Programming Lang: GNU R
Description : mixed-effects gene-expression time-series analysis
To investigate how a drug effects a tissue sample over time,
one commonly determines the transcriptomes at different time points
to distinguish genes that react early from those that react late,
which are steadily going up or down, which are oscillating, and
what molecular process are those subsets of genes contributing to.
.
Time Series Clustering of Gene Expression with Gaussian
Mixed-Effects Models and Smoothing Splines Implementation of a
clustering method for time series gene expression data based on
mixed-effects models with Gaussian variables and non-parametric
cubic splines estimation. The method can robustly account for the
high levels of noise present in typical gene expression time
series datasets.
Remark: This package is maintained by Debian R Packages Maintainers at
https://salsa.debian.org/r-pkg-team/r-bioc-tmixclust
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