[med-svn] [unc-fish] 08/12: New upstream version 1.0+dfsg
Andreas Tille
tille at debian.org
Fri Dec 29 21:42:02 UTC 2017
This is an automated email from the git hooks/post-receive script.
tille pushed a commit to branch master
in repository unc-fish.
commit 4c01c6fb11f18bdb655f9cd1ed04af6c378e2ecc
Author: Andreas Tille <tille at debian.org>
Date: Fri Dec 29 22:36:35 2017 +0100
New upstream version 1.0+dfsg
---
INSTALL.txt | 69 +
LICENSE.txt | 168 +
README.txt | 21 +
SAMPLES.txt | 26 +
debian/changelog | 8 -
debian/compat | 1 -
debian/control | 42 -
debian/copyright | 184 -
debian/createmanpages | 7 -
debian/fish-tests.README.Debian | 9 -
debian/manpages | 1 -
debian/patches/fix_makefile.patch | 26 -
debian/patches/ngopt.patch | 227 -
debian/patches/series | 2 -
debian/rules | 23 -
debian/source/format | 1 -
debian/unc-fish-tests.README.Debian | 9 -
debian/unc-fish-tests.install | 2 -
debian/unc-fish.1 | 42 -
debian/unc-fish.README.Debian | 13 -
debian/unc-fish.install | 1 -
debian/unc-fish.links | 1 -
debian/upstream/metadata | 12 -
debian/watch | 3 -
docs/fishmanual.pdf | Bin 0 -> 117013 bytes
docs/fishmanual/WARNINGS | 3 +
docs/fishmanual/fishmanual.css | 30 +
docs/fishmanual/fishmanual.html | 197 +
docs/fishmanual/images.aux | 1 +
docs/fishmanual/images.log | 313 +
docs/fishmanual/images.pl | 187 +
docs/fishmanual/images.tex | 381 +
docs/fishmanual/img1.png | Bin 0 -> 203 bytes
docs/fishmanual/img10.png | Bin 0 -> 927 bytes
docs/fishmanual/img11.png | Bin 0 -> 1730 bytes
docs/fishmanual/img12.png | Bin 0 -> 201 bytes
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docs/fishmanual/img21.png | Bin 0 -> 262 bytes
docs/fishmanual/img22.png | Bin 0 -> 244 bytes
docs/fishmanual/img23.png | Bin 0 -> 600 bytes
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docs/fishmanual/img26.png | Bin 0 -> 753 bytes
docs/fishmanual/img27.png | Bin 0 -> 258 bytes
docs/fishmanual/img28.png | Bin 0 -> 731 bytes
docs/fishmanual/img29.png | Bin 0 -> 97 bytes
docs/fishmanual/img3.png | Bin 0 -> 348 bytes
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docs/fishmanual/img6.png | Bin 0 -> 509 bytes
docs/fishmanual/img7.png | Bin 0 -> 238 bytes
docs/fishmanual/img8.png | Bin 0 -> 515 bytes
docs/fishmanual/img9.png | Bin 0 -> 534 bytes
docs/fishmanual/index.html | 197 +
docs/fishmanual/internals.pl | 82 +
docs/fishmanual/labels.pl | 157 +
docs/fishmanual/node1.html | 188 +
docs/fishmanual/node10.html | 80 +
docs/fishmanual/node11.html | 75 +
docs/fishmanual/node12.html | 124 +
docs/fishmanual/node13.html | 147 +
docs/fishmanual/node14.html | 100 +
docs/fishmanual/node15.html | 77 +
docs/fishmanual/node16.html | 80 +
docs/fishmanual/node17.html | 94 +
docs/fishmanual/node18.html | 128 +
docs/fishmanual/node19.html | 87 +
docs/fishmanual/node2.html | 97 +
docs/fishmanual/node20.html | 166 +
docs/fishmanual/node21.html | 75 +
docs/fishmanual/node22.html | 201 +
docs/fishmanual/node23.html | 144 +
docs/fishmanual/node24.html | 149 +
docs/fishmanual/node25.html | 110 +
docs/fishmanual/node26.html | 88 +
docs/fishmanual/node27.html | 130 +
docs/fishmanual/node28.html | 85 +
docs/fishmanual/node29.html | 85 +
docs/fishmanual/node3.html | 129 +
docs/fishmanual/node30.html | 101 +
docs/fishmanual/node31.html | 102 +
docs/fishmanual/node32.html | 77 +
docs/fishmanual/node33.html | 79 +
docs/fishmanual/node34.html | 166 +
docs/fishmanual/node35.html | 85 +
docs/fishmanual/node36.html | 86 +
docs/fishmanual/node37.html | 181 +
docs/fishmanual/node38.html | 77 +
docs/fishmanual/node39.html | 113 +
docs/fishmanual/node4.html | 75 +
docs/fishmanual/node40.html | 119 +
docs/fishmanual/node41.html | 87 +
docs/fishmanual/node42.html | 88 +
docs/fishmanual/node43.html | 197 +
docs/fishmanual/node44.html | 126 +
docs/fishmanual/node45.html | 128 +
docs/fishmanual/node46.html | 189 +
docs/fishmanual/node47.html | 77 +
docs/fishmanual/node48.html | 81 +
docs/fishmanual/node5.html | 285 +
docs/fishmanual/node6.html | 78 +
docs/fishmanual/node7.html | 97 +
docs/fishmanual/node8.html | 95 +
docs/fishmanual/node9.html | 89 +
makefile | 16 +
sample_input/blk.out | 6969 ++++++
sample_input/check | 110 +
sample_input/control.txt | 33 +
sample_input/ctg.out | 25509 +++++++++++++++++++
sample_input/data/map1.txt | 6494 +++++
sample_input/data/map2.txt | 4038 +++
sample_input/data/map3.txt | 5221 ++++
sample_input/data/map4.txt | 3825 +++
sample_input/data/map5.txt | 5888 +++++
sample_input/data/match1v1.txt | 44664 ++++++++++++++++++++++++++++++++++
sample_input/data/match1v2.txt | 29477 ++++++++++++++++++++++
sample_input/data/match1v3.txt | 35011 ++++++++++++++++++++++++++
sample_input/data/match1v4.txt | 28336 +++++++++++++++++++++
sample_input/data/match1v5.txt | 36799 ++++++++++++++++++++++++++++
sample_input/data/match2v1.txt | 23897 ++++++++++++++++++
sample_input/data/match2v2.txt | 20010 +++++++++++++++
sample_input/data/match2v3.txt | 21496 ++++++++++++++++
sample_input/data/match2v4.txt | 17409 +++++++++++++
sample_input/data/match2v5.txt | 20171 +++++++++++++++
sample_input/data/match3v1.txt | 30768 +++++++++++++++++++++++
sample_input/data/match3v2.txt | 22947 +++++++++++++++++
sample_input/data/match3v3.txt | 32255 ++++++++++++++++++++++++
sample_input/data/match3v4.txt | 21188 ++++++++++++++++
sample_input/data/match3v5.txt | 28195 +++++++++++++++++++++
sample_input/data/match4v1.txt | 23260 ++++++++++++++++++
sample_input/data/match4v2.txt | 18028 ++++++++++++++
sample_input/data/match4v3.txt | 20181 +++++++++++++++
sample_input/data/match4v4.txt | 19176 +++++++++++++++
sample_input/data/match4v5.txt | 21079 ++++++++++++++++
sample_input/data/match5v1.txt | 33479 +++++++++++++++++++++++++
sample_input/data/match5v2.txt | 22793 +++++++++++++++++
sample_input/data/match5v3.txt | 29137 ++++++++++++++++++++++
sample_input/data/match5v4.txt | 23253 ++++++++++++++++++
sample_input/data/match5v5.txt | 33351 +++++++++++++++++++++++++
sample_input/grd.out | 22101 +++++++++++++++++
sample_output/blocks.txt | 6969 ++++++
sample_output/contigs.txt | 25509 +++++++++++++++++++
sample_output/fish_out.txt | 117 +
sample_output/grids.txt | 22101 +++++++++++++++++
sample_output/simpleblocks.txt | 510 +
src/blocks.h | 180 +
src/dpalgo.h | 138 +
src/fish.cpp | 373 +
src/grids.h | 304 +
src/output_sc.h | 122 +
src/point.cpp | 14 +
src/point.h | 14 +
src/readfile.h | 472 +
src/tandem.h | 324 +
src/usage.h | 176 +
164 files changed, 801236 insertions(+), 614 deletions(-)
diff --git a/INSTALL.txt b/INSTALL.txt
new file mode 100644
index 0000000..59124cc
--- /dev/null
+++ b/INSTALL.txt
@@ -0,0 +1,69 @@
+This README tells you how to install the FISH-1.0 on your
+own system.
+
+
+Source Distribution
+--------------------------------
+ INSTALLATION:
+ 1. "tar -xzvf FISH-1.0.tar.z"
+ 2. "cd FISH-1.0"
+ 3. "make all"
+ 4. "cp bin/fish /usr/local/bin/"
+
+ REQUIREMENTS:
+ 1. g++ compiler. Fish is known to successfully compile with g++ 3.1 and 3.2. To see what version of g++ you have type "g++ -v".
+
+ 2. 32 MB of RAM.
+
+ 3. Operating system: Known to compile and run on Solaris, RedHat 8.0,
+Windows and Mac OS 10.2. It should be compilable and runnable on all systems
+with g++ installed. For windows environments, MinGW(http://www.mingw.org),
+provides a g++ compiler that works well.
+
+
+
+Windows Operating Systems
+-------------------------
+ INSTALLATION:
+ 1. Unzip FISH-1.0-win.zip into "C:\<DESIRED DIRECTORY>".
+ 2. The executable will be located in "C:<DESIRED DIRECTORY>\FISH-1.0\fish.exe".
+ For Example:
+ Unzip to "C:\Program Files"
+ From a command line type: "C:\Program Files\FISH-1.0\fish.exe" -h ,
+ Don't forget the quotations marks!
+ This executes fish and shows the command line options. Please
+ see the manual for further instructions executing fish.
+
+ REQUIREMENTS:
+ 1. 32 MB of RAM.
+ 2. Operating system: Known to run on Windows XP,ME, and NT.
+
+
+Running with the Sample Data
+----------------------------
+From a command line, go to the directory where the sample control file("control.txt") is located:
+Windows: "C:\<DESIRED DIRECTORY>\FISH-1.0\"
+
+And run "fish".
+
+
+Mac OS X
+-------------------------
+ INSTALLATION:
+ 1. Unzip FISH-1.0-osx.zip.
+ 2. The executable will be located in "FISH-1.0/fish".
+
+ REQUIREMENTS:
+ 1. 32 MB of RAM.
+ 2. Operating system: Known to run on 10.2.x
+
+
+
+Running with the Sample Data
+----------------------------
+From a command line, go to the directory where the sample control file("control.txt") is located:
+Windows: "C:\FISH-1.0\"
+Others: "<root_of_FISH>/FISH-1.0/sample_input/"
+
+And run "fish".
+
diff --git a/LICENSE.txt b/LICENSE.txt
new file mode 100644
index 0000000..7a1f623
--- /dev/null
+++ b/LICENSE.txt
@@ -0,0 +1,168 @@
+License Agreement for FISH (Fast Identification of Segmental Homology) version 1.0
+
+FISH is copyright �2003, University of North Carolina at Chapel Hill
+
+As used herein, the term, "Program", below, refers to the source
+code and the derivatives supplied by the authors, and a "work based on the
+Program" means either the Program or any derivative work under copyright law:
+that is to say, a work containing the Program or
+a portion of it, either verbatim or with modifications and/or translated
+into another language. (Hereinafter, translation is included without limitation
+in the term "modification".) Each licensee is addressed as "you".
+
+1. SCOPE
+Activities other than copying, distribution and modification are not
+covered by this License; they are outside its scope. The act of running the
+Program is not restricted, and the output from the Program is covered only
+if its contents constitute a work based on the Program (independent of having
+been made by running the Program). Whether that is true depends on what the
+Program does.
+
+2. USER'S RIGHTS
+You may copy and distribute verbatim copies of the Program's source code
+as you receive it, in any medium, provided that you keep intact all the notices
+that refer to this License and to the absence of any warranty; give any other
+recipients of the Program a copy of this License along with the Program;
+and conspicuously and appropriately publish on each copy a disclaimer of
+warranty and the following statement: "Copyright �2003, University of North
+Carolina at Chapel Hill" If the code has been modified, you also may include
+the following statement: "Modified by [your institution]." You may charge a
+fee for the physical act of transferring a copy, and you may at your option
+offer warranty protection in exchange for a fee.
+
+3. RIGHTS IN DERIVATIVE AND COMBINED WORKS
+It is not the intent of this section to claim rights or contest
+your rights to work written entirely by you; rather, the intent is to exercise
+the right to control the distribution of derivative or collective works based
+on the Program. Aggregation of another work not based on the Program
+with the Program (or with a work based on the Program) on a volume of a storage
+or distribution medium does not bring the other work under the scope of this
+License.
+
+You may modify your copy or copies of the Program or any portion of it,
+thus forming a work based on the Program, and copy and distribute such modifications
+or work under the terms of Section 2 above, provided that you also meet the following
+conditions:
+(a) You must cause the modified files to carry prominent notices stating that you
+changed the files and the date and nature of any change.
+(b) You must cause any work that you distribute or publish, that in whole
+or in part contains or is derived from the Program or any part thereof, to be
+licensed as a whole at no charge to all third parties under the terms of this License.
+
+These requirements apply to the modified work as a whole. If identifiable
+sections of that work are not derived from the Program, and can be reasonably
+considered independent and separate works in themselves, then this License,
+and its terms, do not apply to those sections when you distribute them as
+separate works. But when you distribute the same sections as part of a whole
+which is a work based on the Program, the distribution of the whole must
+be on the terms of this License, whose permissions for other licensees extend
+to the entire whole, and thus to each and every part regardless of who wrote
+it.
+
+4. USER'S PROVISION AND/OR DISTRIBUTION OF SOURCE CODE
+You may copy and distribute the Program (or a work based on it, under
+Section 2) in object code or executable form under the terms of Sections
+1 and 2 above provided that you also accompany it with the complete corresponding
+machine-readable source code, which must be distributed under the terms of
+Sections 1 and 2 above on a medium customarily used for software interchange.
+
+The source code for a work means the preferred form of the work for making
+modifications to it. For an executable work, complete source code means all
+the source code for all modules it contains, plus any associated interface
+definition files, plus the scripts used to control compilation and installation
+of the executable. However, as a special exception, the source code distributed
+need not include anything that is normally distributed (in either source
+or binary form) with the major components (compiler, kernel, and so on) of
+the operating system on which the executable runs, unless that component
+itself accompanies the executable. If distribution of executable or object code
+is made by offering access to copy from a designated place, then offering
+equivalent access to copy the source code from the same place counts as
+distribution of the source code, even though third parties are not compelled
+to copy the source along with the object code.
+
+5. LICENSE RESTRICTIONS
+(a) You may not copy, modify, sublicense, or distribute the Program
+except as expressly provided under this License. Any attempt otherwise to
+copy, modify, sublicense or distribute the Program is void, and will automatically
+terminate your rights under this License. However, parties who have received
+copies, or rights, from you under this License will not have their licenses
+terminated so long as such parties remain in full compliance.
+(b) You are not required to accept this License, since you have not
+signed it. However, nothing else grants you permission to modify or distribute
+the Program or its derivative works. These actions are prohibited by law
+if you do not accept this License. Therefore, by modifying or distributing
+the Program (or any work based on the Program), you indicate your acceptance
+of this License to do so, and all its terms and conditions for copying, distributing
+or modifying the Program or works based on it.
+(c) If, as a consequence of a court judgment or allegation of patent
+infringement or for any other reason (not limited to patent issues), conditions
+are imposed on you (whether by court order, agreement or otherwise) that
+contradict the conditions of this License, they do not excuse you from the
+conditions of this License. If you cannot distribute so as to satisfy simultaneously
+your obligations under this License and any other pertinent obligations,
+then as a consequence you may not distribute the Program at all. For example,
+if a patent license would not permit royalty-free redistribution of the Program
+by all those who receive copies directly or indirectly through you, then
+the only way you could satisfy both it and this License would be to refrain
+entirely from distribution of the Program.
+
+It is not the purpose of this section to induce you to infringe any patents
+or other property right claims or to contest validity of any such claims;
+ this section has the sole purpose of protecting the integrity of the free
+software distribution system, which is implemented by public license practices.
+Many people have made generous contributions to the wide range of software
+distributed through that system in reliance on consistent application of
+that system; it is up to the author/donor to decide if he or she is willing
+to distribute software through any other system and a licensee cannot impose
+that choice.
+
+6. LICENSE CONVEYS TO SUBSEQUENT RECIPIENTS
+Each time you redistribute the Program (or any work based on the Program),
+the recipient automatically receives a license from the original licensor
+to copy, distribute or modify the Program subject to these terms and conditions.
+You may not impose any further restrictions on the recipients' exercise of
+the rights granted herein. You are not responsible for enforcing compliance
+by third parties to this License.
+
+7. SEVERABILITY
+If any portion of this license or any portion of any section of this
+license is held invalid or unenforceable under any particular circumstance,
+the balance of the section is intended to apply and the section as a whole
+is intended to apply in other circumstances.
+
+8. NO WARRANTY
+BECAUSE THE PROGRAM IS LICENSED FREE OF CHARGE, THERE IS NO WARRANTY
+FOR THE PROGRAM, TO THE EXTENT PERMITTED BY APPLICABLE LAW. EXCEPT WHEN OTHERWISE
+STATED IN WRITING THE COPYRIGHT HOLDERS AND/OR OTHER PARTIES PROVIDE THE
+PROGRAM "AS IS" WITHOUT WARRANTY OF ANY KIND, EITHER EXPRESSED OR IMPLIED,
+INCLUDING, BUT NOT LIMITED TO, THE IMPLIED WARRANTIES OF MERCHANTABILITY
+AND FITNESS FOR A PARTICULAR PURPOSE. THE ENTIRE RISK AS TO THE QUALITY AND
+PERFORMANCE OF THE PROGRAM IS WITH YOU. SHOULD THE PROGRAM PROVE DEFECTIVE,
+YOU ASSUME THE COST OF ALL NECESSARY SERVICING, REPAIR OR CORRECTION.
+
+IN NO EVENT UNLESS REQUIRED BY APPLICABLE LAW OR AGREED TO IN WRITING
+WILL ANY COPYRIGHT HOLDER, OR ANY OTHER PARTY WHO MAY MODIFY AND/OR REDISTRIBUTE
+THE PROGRAM AS PERMITTED ABOVE, BE LIABLE TO YOU FOR DAMAGES, INCLUDING ANY
+GENERAL, SPECIAL, INCIDENTAL OR CONSEQUENTIAL DAMAGES ARISING OUT OF THE
+USE OR INABILITY TO USE THE PROGRAM (INCLUDING BUT NOT LIMITED TO LOSS OF
+DATA OR DATA BEING RENDERED INACCURATE OR LOSSES SUSTAINED BY YOU OR THIRD
+PARTIES OR A FAILURE OF THE PROGRAM TO OPERATE WITH ANY OTHER PROGRAMS),
+EVEN IF SUCH HOLDER OR OTHER PARTY HAS BEEN ADVISED OF THE POSSIBILITY OF
+SUCH DAMAGES. BECAUSE THE PROGRAM IS LICENSED FREE OF CHARGE, THERE IS NO WARRANTY
+FOR THE PROGRAM, TO THE EXTENT PERMITTED BY APPLICABLE LAW. EXCEPT WHEN OTHERWISE
+STATED IN WRITING THE COPYRIGHT HOLDERS AND/OR OTHER PARTIES PROVIDE THE
+PROGRAM "AS IS" WITHOUT WARRANTY OF ANY KIND, EITHER EXPRESSED OR IMPLIED,
+INCLUDING, BUT NOT LIMITED TO, THE IMPLIED WARRANTIES OF MERCHANTABILITY
+AND FITNESS FOR A PARTICULAR PURPOSE. THE ENTIRE RISK AS TO THE QUALITY AND
+PERFORMANCE OF THE PROGRAM IS WITH YOU. SHOULD THE PROGRAM PROVE DEFECTIVE,
+YOU ASSUME THE COST OF ALL NECESSARY SERVICING, REPAIR OR CORRECTION.
+
+IN NO EVENT UNLESS REQUIRED BY APPLICABLE LAW OR AGREED TO IN WRITING
+WILL ANY COPYRIGHT HOLDER, OR ANY OTHER PARTY WHO MAY MODIFY AND/OR REDISTRIBUTE
+THE PROGRAM AS PERMITTED ABOVE, BE LIABLE TO YOU FOR DAMAGES, INCLUDING ANY
+GENERAL, SPECIAL, INCIDENTAL OR CONSEQUENTIAL DAMAGES ARISING OUT OF THE
+USE OR INABILITY TO USE THE PROGRAM (INCLUDING BUT NOT LIMITED TO LOSS OF
+DATA OR DATA BEING RENDERED INACCURATE OR LOSSES SUSTAINED BY YOU OR THIRD
+PARTIES OR A FAILURE OF THE PROGRAM TO OPERATE WITH ANY OTHER PROGRAMS),
+EVEN IF SUCH HOLDER OR OTHER PARTY HAS BEEN ADVISED OF THE POSSIBILITY OF
+SUCH DAMAGES.
diff --git a/README.txt b/README.txt
new file mode 100644
index 0000000..7f9c9bf
--- /dev/null
+++ b/README.txt
@@ -0,0 +1,21 @@
+README for FISH.
+
+FILES IN THIS DISTRIBUTION:
+1. SAMPLES.txt -- tells you how to run and view examples. Sample data is provided.
+2. INSTALL.txt -- tells you how to compile and install FISH-1.0 on your own system.
+3. makefile -- for compiling the source code
+4. LICENSE.txt -- to tell you what you can and cannot do with this program.
+5. README.txt -- the one you are currently reading
+
+DIRECTORIES IN THIS DISTRIBUTION:
+1. bin -- after compiling source code, this is where the "fish" executable is copied.
+2. docs -- contains the manual in postscript,html,and pdf formats.
+3. sample_input -- contains sample data and a sample control file.
+4. sample_ouput -- contains sample output
+5. src -- directory contain all source files.
+
+
+THE MANUAL:
+Please read the manual before using FISH-1.0. It is located in "docs" and is
+called "fishmanual.pdf".
+
diff --git a/SAMPLES.txt b/SAMPLES.txt
new file mode 100644
index 0000000..e9e4e3b
--- /dev/null
+++ b/SAMPLES.txt
@@ -0,0 +1,26 @@
+Samples...
+Two directories exist in the FISH-1.0 package, "sample_input" and
+"sample_output." They are described below.
+
+sample_input
+------------
+Inside the sample_input directory of the FISH distributions is a control
+file(control.txt) and a data directory called "data" which contains all
+the files mentioned in "control.txt."
+
+
+sample_output
+-------------
+The following list consists of sample outputs created after running the
+following command on the sample_input data:
+"fish -b blocks.txt -B simpleblocks.txt -g grids.txt -C contigs.txt > fish_out.txt"
+ ** the ">" in the above sends the ouput to the file "fish_out.txt"
+
+* blocks.txt -- human readable output of the homologous blocks detected by
+ FISH.
+* simpleblocks.txt -- computer readable output of the homologous blocks
+ detected by FISH.
+* grids.txt -- output of grid FISH constructed to find blocks.
+* contigs.txt -- output of contigs FISH constructed to create grids.
+* fishout.txt -- standard output of FISH.
+
diff --git a/debian/changelog b/debian/changelog
deleted file mode 100644
index a79aeda..0000000
--- a/debian/changelog
+++ /dev/null
@@ -1,8 +0,0 @@
-unc-fish (1.0+dfsg-1) UNRELEASED; urgency=low
-
- * Initial release (Closes: #<bug>)
- TODO: Find reason for failure:
- $ /usr/lib/unc-fish/fish -b blocks.txt -B simpleblocks.txt -g grids.txt -C contigs.txt
- Segmentation fault
-
- -- Andreas Tille <tille at debian.org> Fri, 14 Feb 2014 09:23:04 +0100
diff --git a/debian/compat b/debian/compat
deleted file mode 100644
index ec63514..0000000
--- a/debian/compat
+++ /dev/null
@@ -1 +0,0 @@
-9
diff --git a/debian/control b/debian/control
deleted file mode 100644
index 8f5bb39..0000000
--- a/debian/control
+++ /dev/null
@@ -1,42 +0,0 @@
-Source: unc-fish
-Section: science
-Priority: optional
-Maintainer: Debian Med Packaging Team <debian-med-packaging at lists.alioth.debian.org>
-Uploaders: Andreas Tille <tille at debian.org>
-Build-Depends: debhelper (>= 9)
-Standards-Version: 3.9.5
-Vcs-Browser: http://anonscm.debian.org/viewvc/debian-med/trunk/packages/unc-fish/trunk/
-Vcs-Svn: svn://anonscm.debian.org/debian-med/trunk/packages/unc-fish/trunk/
-Homepage: http://labs.bio.unc.edu/Vision/FISH/
-
-Package: unc-fish
-Architecture: any
-Depends: ${shlibs:Depends},
- ${misc:Depends}
-Description: Fast Identification of Segmental Homology
- FISH is software for identifying regions of common ancestry between
- genome maps. Fast identification and statistical evaluation of
- segmental homologies in comparative maps.
- .
- Development and maintenance of FISH is supported by funding from the
- National Science Foundation (Plant Genome Research Program Grants
- DBI-0110069 and DBI-0227314 to TJV and DMS-0102008 to PPC).
-
-Package: unc-fish-tests
-Architecture: all
-Priority: extra
-Enhances: unc-fish
-Depends: ${misc:Depends}
-Suggests: unc-fish
-Description: Tests for Fast Identification of Segmental Homology (fish)
- FISH is software for identifying regions of common ancestry between
- genome maps. Fast identification and statistical evaluation of
- segmental homologies in comparative maps.
- .
- Development and maintenance of FISH is supported by funding from the
- National Science Foundation (Plant Genome Research Program Grants
- DBI-0110069 and DBI-0227314 to TJV and DMS-0102008 to PPC).
- .
- This package contains the example data provided by upstream to enable
- the user to test fish.
-
diff --git a/debian/copyright b/debian/copyright
deleted file mode 100644
index 76e82b1..0000000
--- a/debian/copyright
+++ /dev/null
@@ -1,184 +0,0 @@
-Format: http://www.debian.org/doc/packaging-manuals/copyright-format/1.0/
-Upstream-Name: FISH
-Upstream-Contact: Todd J. Vision <tjv at bio.unc.edu>
-Source: http://labs.bio.unc.edu/Vision/FISH/
-Files-Excluded:
- bin
- docs/fishmanual.ps
- CVS
- */CVS
- */*/CVS
-
-Files: *
-Copyright: 2003 University of North Carolina at Chapel Hill
-License: LicenseAgreementFISH
- As used herein, the term, "Program", below, refers to the source
- code and the derivatives supplied by the authors, and a "work based on the
- Program" means either the Program or any derivative work under copyright law:
- that is to say, a work containing the Program or
- a portion of it, either verbatim or with modifications and/or translated
- into another language. (Hereinafter, translation is included without limitation
- in the term "modification".) Each licensee is addressed as "you".
- .
- 1. SCOPE
- Activities other than copying, distribution and modification are not
- covered by this License; they are outside its scope. The act of running the
- Program is not restricted, and the output from the Program is covered only
- if its contents constitute a work based on the Program (independent of having
- been made by running the Program). Whether that is true depends on what the
- Program does.
- .
- 2. USER'S RIGHTS
- You may copy and distribute verbatim copies of the Program's source code
- as you receive it, in any medium, provided that you keep intact all the notices
- that refer to this License and to the absence of any warranty; give any other
- recipients of the Program a copy of this License along with the Program;
- and conspicuously and appropriately publish on each copy a disclaimer of
- warranty and the following statement: "Copyright ©2003, University of North
- Carolina at Chapel Hill" If the code has been modified, you also may include
- the following statement: "Modified by [your institution]." You may charge a
- fee for the physical act of transferring a copy, and you may at your option
- offer warranty protection in exchange for a fee.
- .
- 3. RIGHTS IN DERIVATIVE AND COMBINED WORKS
- It is not the intent of this section to claim rights or contest
- your rights to work written entirely by you; rather, the intent is to exercise
- the right to control the distribution of derivative or collective works based
- on the Program. Aggregation of another work not based on the Program
- with the Program (or with a work based on the Program) on a volume of a storage
- or distribution medium does not bring the other work under the scope of this
- License.
- .
- You may modify your copy or copies of the Program or any portion of it,
- thus forming a work based on the Program, and copy and distribute such modifications
- or work under the terms of Section 2 above, provided that you also meet the following
- conditions:
- (a) You must cause the modified files to carry prominent notices stating that you
- changed the files and the date and nature of any change.
- (b) You must cause any work that you distribute or publish, that in whole
- or in part contains or is derived from the Program or any part thereof, to be
- licensed as a whole at no charge to all third parties under the terms of this License.
- .
- These requirements apply to the modified work as a whole. If identifiable
- sections of that work are not derived from the Program, and can be reasonably
- considered independent and separate works in themselves, then this License,
- and its terms, do not apply to those sections when you distribute them as
- separate works. But when you distribute the same sections as part of a whole
- which is a work based on the Program, the distribution of the whole must
- be on the terms of this License, whose permissions for other licensees extend
- to the entire whole, and thus to each and every part regardless of who wrote
- it.
- .
- 4. USER'S PROVISION AND/OR DISTRIBUTION OF SOURCE CODE
- You may copy and distribute the Program (or a work based on it, under
- Section 2) in object code or executable form under the terms of Sections
- 1 and 2 above provided that you also accompany it with the complete corresponding
- machine-readable source code, which must be distributed under the terms of
- Sections 1 and 2 above on a medium customarily used for software interchange.
- .
- The source code for a work means the preferred form of the work for making
- modifications to it. For an executable work, complete source code means all
- the source code for all modules it contains, plus any associated interface
- definition files, plus the scripts used to control compilation and installation
- of the executable. However, as a special exception, the source code distributed
- need not include anything that is normally distributed (in either source
- or binary form) with the major components (compiler, kernel, and so on) of
- the operating system on which the executable runs, unless that component
- itself accompanies the executable. If distribution of executable or object code
- is made by offering access to copy from a designated place, then offering
- equivalent access to copy the source code from the same place counts as
- distribution of the source code, even though third parties are not compelled
- to copy the source along with the object code.
- .
- 5. LICENSE RESTRICTIONS
- (a) You may not copy, modify, sublicense, or distribute the Program
- except as expressly provided under this License. Any attempt otherwise to
- copy, modify, sublicense or distribute the Program is void, and will automatically
- terminate your rights under this License. However, parties who have received
- copies, or rights, from you under this License will not have their licenses
- terminated so long as such parties remain in full compliance.
- (b) You are not required to accept this License, since you have not
- signed it. However, nothing else grants you permission to modify or distribute
- the Program or its derivative works. These actions are prohibited by law
- if you do not accept this License. Therefore, by modifying or distributing
- the Program (or any work based on the Program), you indicate your acceptance
- of this License to do so, and all its terms and conditions for copying, distributing
- or modifying the Program or works based on it.
- (c) If, as a consequence of a court judgment or allegation of patent
- infringement or for any other reason (not limited to patent issues), conditions
- are imposed on you (whether by court order, agreement or otherwise) that
- contradict the conditions of this License, they do not excuse you from the
- conditions of this License. If you cannot distribute so as to satisfy simultaneously
- your obligations under this License and any other pertinent obligations,
- then as a consequence you may not distribute the Program at all. For example,
- if a patent license would not permit royalty-free redistribution of the Program
- by all those who receive copies directly or indirectly through you, then
- the only way you could satisfy both it and this License would be to refrain
- entirely from distribution of the Program.
- .
- It is not the purpose of this section to induce you to infringe any patents
- or other property right claims or to contest validity of any such claims;
- this section has the sole purpose of protecting the integrity of the free
- software distribution system, which is implemented by public license practices.
- Many people have made generous contributions to the wide range of software
- distributed through that system in reliance on consistent application of
- that system; it is up to the author/donor to decide if he or she is willing
- to distribute software through any other system and a licensee cannot impose
- that choice.
- .
- 6. LICENSE CONVEYS TO SUBSEQUENT RECIPIENTS
- Each time you redistribute the Program (or any work based on the Program),
- the recipient automatically receives a license from the original licensor
- to copy, distribute or modify the Program subject to these terms and conditions.
- You may not impose any further restrictions on the recipients' exercise of
- the rights granted herein. You are not responsible for enforcing compliance
- by third parties to this License.
- .
- 7. SEVERABILITY
- If any portion of this license or any portion of any section of this
- license is held invalid or unenforceable under any particular circumstance,
- the balance of the section is intended to apply and the section as a whole
- is intended to apply in other circumstances.
- .
- 8. NO WARRANTY
- BECAUSE THE PROGRAM IS LICENSED FREE OF CHARGE, THERE IS NO WARRANTY
- FOR THE PROGRAM, TO THE EXTENT PERMITTED BY APPLICABLE LAW. EXCEPT WHEN OTHERWISE
- STATED IN WRITING THE COPYRIGHT HOLDERS AND/OR OTHER PARTIES PROVIDE THE
- PROGRAM "AS IS" WITHOUT WARRANTY OF ANY KIND, EITHER EXPRESSED OR IMPLIED,
- INCLUDING, BUT NOT LIMITED TO, THE IMPLIED WARRANTIES OF MERCHANTABILITY
- AND FITNESS FOR A PARTICULAR PURPOSE. THE ENTIRE RISK AS TO THE QUALITY AND
- PERFORMANCE OF THE PROGRAM IS WITH YOU. SHOULD THE PROGRAM PROVE DEFECTIVE,
- YOU ASSUME THE COST OF ALL NECESSARY SERVICING, REPAIR OR CORRECTION.
- .
- IN NO EVENT UNLESS REQUIRED BY APPLICABLE LAW OR AGREED TO IN WRITING
- WILL ANY COPYRIGHT HOLDER, OR ANY OTHER PARTY WHO MAY MODIFY AND/OR REDISTRIBUTE
- THE PROGRAM AS PERMITTED ABOVE, BE LIABLE TO YOU FOR DAMAGES, INCLUDING ANY
- GENERAL, SPECIAL, INCIDENTAL OR CONSEQUENTIAL DAMAGES ARISING OUT OF THE
- USE OR INABILITY TO USE THE PROGRAM (INCLUDING BUT NOT LIMITED TO LOSS OF
- DATA OR DATA BEING RENDERED INACCURATE OR LOSSES SUSTAINED BY YOU OR THIRD
- PARTIES OR A FAILURE OF THE PROGRAM TO OPERATE WITH ANY OTHER PROGRAMS),
- EVEN IF SUCH HOLDER OR OTHER PARTY HAS BEEN ADVISED OF THE POSSIBILITY OF
- SUCH DAMAGES. BECAUSE THE PROGRAM IS LICENSED FREE OF CHARGE, THERE IS NO WARRANTY
- FOR THE PROGRAM, TO THE EXTENT PERMITTED BY APPLICABLE LAW. EXCEPT WHEN OTHERWISE
- STATED IN WRITING THE COPYRIGHT HOLDERS AND/OR OTHER PARTIES PROVIDE THE
- PROGRAM "AS IS" WITHOUT WARRANTY OF ANY KIND, EITHER EXPRESSED OR IMPLIED,
- INCLUDING, BUT NOT LIMITED TO, THE IMPLIED WARRANTIES OF MERCHANTABILITY
- AND FITNESS FOR A PARTICULAR PURPOSE. THE ENTIRE RISK AS TO THE QUALITY AND
- PERFORMANCE OF THE PROGRAM IS WITH YOU. SHOULD THE PROGRAM PROVE DEFECTIVE,
- YOU ASSUME THE COST OF ALL NECESSARY SERVICING, REPAIR OR CORRECTION.
- .
- IN NO EVENT UNLESS REQUIRED BY APPLICABLE LAW OR AGREED TO IN WRITING
- WILL ANY COPYRIGHT HOLDER, OR ANY OTHER PARTY WHO MAY MODIFY AND/OR REDISTRIBUTE
- THE PROGRAM AS PERMITTED ABOVE, BE LIABLE TO YOU FOR DAMAGES, INCLUDING ANY
- GENERAL, SPECIAL, INCIDENTAL OR CONSEQUENTIAL DAMAGES ARISING OUT OF THE
- USE OR INABILITY TO USE THE PROGRAM (INCLUDING BUT NOT LIMITED TO LOSS OF
- DATA OR DATA BEING RENDERED INACCURATE OR LOSSES SUSTAINED BY YOU OR THIRD
- PARTIES OR A FAILURE OF THE PROGRAM TO OPERATE WITH ANY OTHER PROGRAMS),
- EVEN IF SUCH HOLDER OR OTHER PARTY HAS BEEN ADVISED OF THE POSSIBILITY OF
- SUCH DAMAGES.
-
-Files: debian/*
-Copyright: 2014 Andreas Tille <tille at debian.org>
-License: GPLv3+
- The full text of GPL license version 3 can be found at
- /usr/share/common-licenses/GPL-3 .
diff --git a/debian/createmanpages b/debian/createmanpages
deleted file mode 100755
index 50e5132..0000000
--- a/debian/createmanpages
+++ /dev/null
@@ -1,7 +0,0 @@
-#!/bin/sh
-VERSION=`dpkg-parsechangelog | awk '/^Version:/ {print $2}' | sed -e 's/^[0-9]*://' -e 's/-.*//'`
-MANDIR=debian
-mkdir -p $MANDIR
-help2man --no-info --no-discard-stderr \
- --name='Fast Identification of Segmental Homology' \
- --version-string="$VERSION" unc-fish > $MANDIR/unc-fish.1
diff --git a/debian/fish-tests.README.Debian b/debian/fish-tests.README.Debian
deleted file mode 100644
index 7a5d1a5..0000000
--- a/debian/fish-tests.README.Debian
+++ /dev/null
@@ -1,9 +0,0 @@
-Test data for package fish
-==========================
-
-The data are installed at
-
- /var/lib/fish
-
-See the file SAMPLE.txt there for more instructions.
-
diff --git a/debian/manpages b/debian/manpages
deleted file mode 100644
index 0f65186..0000000
--- a/debian/manpages
+++ /dev/null
@@ -1 +0,0 @@
-debian/*.1
diff --git a/debian/patches/fix_makefile.patch b/debian/patches/fix_makefile.patch
deleted file mode 100644
index 3179287..0000000
--- a/debian/patches/fix_makefile.patch
+++ /dev/null
@@ -1,26 +0,0 @@
-Author: Andreas Tille <tille at debian.org>
-Last-Changed: Fri, 14 Feb 2014 09:23:04 +0100
-Description: Fix very basic makefile
- - Fix clean target
- - propagate build options
-
---- a/makefile
-+++ b/makefile
-@@ -3,14 +3,14 @@ CC = g++ -ggdb
-
-
- all : realall
-- make bin
-+ # make bin
-
- realall :
-- (cd ./src; $(CC) -c point.cpp; $(CC) fish.cpp point.o -o fish)
-+ (cd ./src; $(CC) $(CPPFLAGS) $(CXXFLAGS) $(LDFLAGS) point.cpp fish.cpp -o fish)
-
- bin :
- mkdir bin
- mv src/fish ./bin
- clean :
-- (cd src ; rm *.o)
-+ (cd src ; rm -f *.o fish)
- (rm -rf ./bin)
diff --git a/debian/patches/ngopt.patch b/debian/patches/ngopt.patch
deleted file mode 100644
index f4cf8d4..0000000
--- a/debian/patches/ngopt.patch
+++ /dev/null
@@ -1,227 +0,0 @@
-Author: Andreas Tille <tille at debian.org>
-Last-Changed: Fri, 14 Feb 2014 09:23:04 +0100
-Description: Patch taken from ngopt at
- http://code.google.com/p/ngopt/source/browse/#svn%2Ftrunk%2FFISH%2Fsrc
- Without this patch the original code segfaults with the sample data set.
- However, the code is not only fixing a code problem but also does some other
- change of functionality - so the test data can not be reproduced with this
- patch.
-
---- a/src/blocks.h
-+++ b/src/blocks.h
-@@ -69,6 +69,8 @@ if(PRINT_BLOCK)
- int tempdist=0;
- ofstream p2b;
- p2b.open(Block_File.c_str(),ios::out);
-+/* Lets make the output easier to parse.
-+ * Get rid of this stuff first.
- p2b<<get_time_stamp()<<"";
- p2b<<"FISH v1.0\n";
- p2b<<"FISH is copyright (c)2003, University of North Carolina at Chapel Hill\n";
-@@ -79,15 +81,17 @@ if(PRINT_BLOCK)
- p2b<<"\ttotal_features = "<<Total_Features<<"\n\ttotal_cells = "<<Total_Cells<<"\n";
- p2b<<"\th = "<<prob<<"\n\td_T = "<<Thresh_Dist<<"\n\tMin_Block_Size = "<<Min_Block_Size;
- p2b<<"\n\tblock_prob = "<<BLOCK_PROB<<"\n\ttotal_blocks = "<<block_list.size()<<"\n\n\n";
--
-+*/
-+ // make the output tab-delimited
-+ p2b<<"contig1\tcontig2\tblock\tpoint\tdist\tmarkers\torientation"<<endl;
- for(i=0;i<block_list.size();i++)
- {
-
- dataj=block_list[i].block.begin();
-- p2b<<"-block "<<i<<endl;
-- p2b<<setw(10)<<"points"<<setw(10)<<"contig1"<<setw(10)<<"contig2"<<endl;
-- p2b<<setw(9)<<block_list[i].block.size()<<setw(9)<<MATCHES[*dataj].contig1<<setw(9)<<MATCHES[*dataj].contig2<<"\n\n";
-- p2b<<"\tpoint\tdist\tmarkers\torientation"<<endl;
-+ // p2b<<"-block "<<i<<endl;
-+ // p2b<<setw(10)<<"points"<<setw(10)<<"contig1"<<setw(10)<<"contig2"<<endl;
-+ // p2b<<setw(9)<<block_list[i].block.size()<<setw(9)<<MATCHES[*dataj].contig1<<setw(9)<<MATCHES[*dataj].contig2<<"\n\n";
-+ // p2b<<"block\tpoint\tdist\tmarkers\torientation"<<endl;
-
- tempy=MATCHES[*dataj].feat.y;
- tempx=MATCHES[*dataj].feat.x;
-@@ -96,35 +100,44 @@ if(PRINT_BLOCK)
- {
- tempdist=(MATCHES[*dataj].feat.y-tempy)+abs(MATCHES[*dataj].feat.x-tempx);
-
-- p2b<<"\t"<<*dataj<<"\t"<<tempdist<<"\t{";
--
-- for(j=0;j<f2g[MATCHES[*dataj].feat.y].gene_list.size();j++)
-- p2b<<f2g[MATCHES[*dataj].feat.y].gene_list[j]<<" ";
-+ p2b<<MATCHES[*dataj].contig1<<"\t"<<MATCHES[*dataj].contig2<<"\t"<<i<<"\t"<<*dataj<<"\t"<<tempdist<<"\t";
-
-- p2b<<"}{";
-+ for(j=0;j<f2g[MATCHES[*dataj].feat.y].gene_list.size();j++){
-+ p2b<<f2g[MATCHES[*dataj].feat.y].gene_list[j];
-+ if (j < f2g[MATCHES[*dataj].feat.y].gene_list.size() - 1)
-+ p2b <<",";
-+ }
-+ p2b<<"\t";
-+ // p2b<<"}{";
-+
-+ for(j=0;j<f2g[MATCHES[*dataj].feat.x].gene_list.size();j++){
-+ p2b<<f2g[MATCHES[*dataj].feat.x].gene_list[j];
-+ if (j < f2g[MATCHES[*dataj].feat.x].gene_list.size() - 1)
-+ p2b << ",";
-+ }
-
-- for(j=0;j<f2g[MATCHES[*dataj].feat.x].gene_list.size();j++)
-- p2b<<f2g[MATCHES[*dataj].feat.x].gene_list[j]<<" ";
-+ p2b<<"\t"<<MATCHES[*dataj].feat.direction<<"\n";
-+// p2b<<"}\t"<<MATCHES[*dataj].feat.direction<<"\n";
-
-- p2b<<"}\t"<<MATCHES[*dataj].feat.direction<<"\n";
- tempx=MATCHES[*dataj].feat.x;
- tempy=MATCHES[*dataj].feat.y;
-
- }
-
-
-- p2b<<"\n\n";
-+ //p2b<<"\n\n";
-
- }
-
--
-+/*
- p2b<<"-by contig\n";
- p2b<<setw(10)<<"contig1"<<setw(10)<<"contig2"<<setw(10)<<"blocks\n";
- for(i=0;i<sub_grid.size();i++)
- p2b<<setw(9)<<sub_grid[i].contig1<<setw(9)<<sub_grid[i].contig2<<setw(9)<<sub_grid[i].blocks<<endl;
--
-- p2b<<"\n-by size\n";
-- p2b<<setw(10)<<"points"<<setw(10)<<"obs"<<setw(10)<<"exp"<<setw(25)<<"p\n";
-+*/
-+// p2b<<"\n-by size\n";
-+ p2b<<"-by size\n";
-+ p2b<<"points"<<setw(10)<<"obs"<<setw(10)<<"exp"<<setw(25)<<"p\n";
- for(l=0;l<FREQ.size();l++)
- {
- if(FREQ[l]>0)
-@@ -132,7 +145,8 @@ if(PRINT_BLOCK)
- p_u=pow(n*prob,l)*prob;
- pvalue=1-exp(-1*Total_Cells*p_u);
- expected_blocks=Total_Cells*p_u;
-- p2b<<setw(9)<<l+1<<setw(9)<<FREQ[l]<<setw(15)<<scientific<<setprecision(2)<<expected_blocks<<setw(25)<<scientific<<pvalue<<"\n";
-+// p2b<<setw(9)<<l+1<<setw(9)<<FREQ[l]<<setw(15)<<scientific<<setprecision(2)<<expected_blocks<<setw(25)<<scientific<<pvalue<<"\n";
-+ p2b<<l+1<<"\t"<<FREQ[l]<<"\t"<<scientific<<setprecision(2)<<expected_blocks<<"\t"<<scientific<<pvalue<<"\n";
- }
- }
-
---- a/src/fish.cpp
-+++ b/src/fish.cpp
-@@ -39,7 +39,7 @@ string Block_File_S;
- bool MAX_SCORE=true;
- int TOP_HITS=5;
- int Max_Distance=10;
--int Min_Score=200;
-+int Min_Score=13;
- double Threshold=0.05;
- int Min_Block_Size=3;
- float BLOCK_PROB=.001;
---- a/src/readfile.h
-+++ b/src/readfile.h
-@@ -240,7 +240,7 @@ GENE_LIST::iterator chk_pos2;
- if(temp_map.size()>0)
- {
- sub_grid[sub_grid.size()-1].ext=true;
-- image_maps.insert(make_pair(contig1+contig2,temp_map));
-+ image_maps.insert(make_pair(contig1+"&"+contig2,temp_map));
- }
-
- temp_map.clear();
-@@ -327,7 +327,7 @@ GENE_LIST::iterator chk_pos2;
- if(image_maps.size()>0)
- {
-
-- pos1=image_maps.find(contig1+contig2);
-+ pos1=image_maps.find(contig1+"&"+contig2);
-
- if(pos1==image_maps.end())
- {
-@@ -339,16 +339,16 @@ GENE_LIST::iterator chk_pos2;
- {
- inserted++;
- mapexists=true;
-- tempscore=(image_maps[contig1+contig2][contig1+key_y+'&'+contig2+key_x]);
-+ tempscore=(image_maps[contig1+"&"+contig2][contig1+key_y+'&'+contig2+key_x]);
-
- if(MAX_SCORE==true)
-- image_maps[contig1+contig2][contig1+key_y+'&'+contig2+key_x]=(MAX(tempscore,score));
-+ image_maps[contig1+"&"+contig2][contig1+key_y+'&'+contig2+key_x]=(MAX(tempscore,score));
- else
- {
- if(tempscore==0)
-- image_maps[contig1+contig2][contig1+key_y+'&'+contig2+key_x]=(score);
-+ image_maps[contig1+"&"+contig2][contig1+key_y+'&'+contig2+key_x]=(score);
- else
-- image_maps[contig1+contig2][contig1+key_y+'&'+contig2+key_x]=(AVG(tempscore,score));
-+ image_maps[contig1+"&"+contig2][contig1+key_y+'&'+contig2+key_x]=(AVG(tempscore,score));
- }
-
- }
-@@ -365,7 +365,7 @@ GENE_LIST::iterator chk_pos2;
- }
-
- if(mapexists==false)
-- image_maps.insert(make_pair(contig1+contig2,temp_map));
-+ image_maps.insert(make_pair(contig1+"&"+contig2,temp_map));
-
- temp_map.clear();
-
-@@ -400,7 +400,7 @@ GENE_LIST::iterator chk_pos2;
- {
- contig1=i2s(sub_grid[k].contig1);
- contig2=i2s(sub_grid[k].contig2);
-- contigs=contig1+contig2;
-+ contigs=contig1+"&"+contig2;
- for(pos2=image_maps[contigs].begin();pos2!=image_maps[contigs].end();++pos2)
- {
- //cout<<"The firs key "<<pos2->first;
-@@ -433,7 +433,7 @@ if(GENE.size()==0 ||GENE.size()<=2)
-
-
-
--image_maps.~map();
-+//image_maps.~map();
-
- INV_GENE.clear();
- INV_GENE=GENE;
---- a/src/usage.h
-+++ b/src/usage.h
-@@ -23,7 +23,6 @@ void process_arguments(int argc, char* a
- check(i,argv,argc);
- Block_File=argv[++i];
- PRINT_BLOCK=true;
--
- }
-
- else if(temp=="-B")
-@@ -43,7 +42,7 @@ void process_arguments(int argc, char* a
- }
-
- else if(temp=="-off")
-- Max_Distance=0;
-+ Max_Distance=-1;
-
- else if(temp=="-q")
- QUIET_MODE=true;
-@@ -144,7 +143,7 @@ void process_arguments(int argc, char* a
- i++;
-
- }
--
-+ Max_Distance=-1;
- }
-
- void check(int j, char* argv[],int argc)
-@@ -167,7 +166,7 @@ void usage(void)
- {
- cerr<<"usage: fish [-f Control_File |control.txt]\n";
- cerr<<"\t[-b Block_File] [-g Grid_File] [-C Contig_File]\n";
-- cerr<<"\t[-D Max_Distance |10] [-S Min_Score |200] [-T Threshold |.05]\n";
-+ cerr<<"\t[-D Max_Distance |10] [-S Min_Score |13] [-T Threshold |.05]\n";
- cerr<<"\t[-m Min_Block_Size |3] [-off Turn off Detandemize] [-h help]\n";
- cerr<<"\t[-H Top_Hits |5] [-A Average_Score Selection | Max_Score]\n";
- cerr<<"\t[-p BLOCK_PROB |.001] [-B Block_File_Simple][-q QUIET_MODE]\n";
diff --git a/debian/patches/series b/debian/patches/series
deleted file mode 100644
index 7ff9430..0000000
--- a/debian/patches/series
+++ /dev/null
@@ -1,2 +0,0 @@
-fix_makefile.patch
-ngopt.patch
diff --git a/debian/rules b/debian/rules
deleted file mode 100755
index 58ec00b..0000000
--- a/debian/rules
+++ /dev/null
@@ -1,23 +0,0 @@
-#!/usr/bin/make -f
-
-# DH_VERBOSE := 1
-
-# some helpful variables - uncomment them if needed
-# shamelessly stolen from http://jmtd.net/log/awk/
-#DEBVERS := $(shell dpkg-parsechangelog | awk '/^Version:/ {print $$2}')
-#VERSION := $(shell echo '$(DEBVERS)' | sed -e 's/^[0-9]*://' -e 's/-.*//')
-#DEBFLAVOR := $(shell dpkg-parsechangelog | awk '/^Distribution:/ {print $$2}')
-#DEBPKGNAME := $(shell dpkg-parsechangelog | awk '/^Source:/ {print $$2}')
-#DEBIAN_BRANCH := $(shell awk 'BEGIN{FS="[= ]+"} /debian-branch/ {print $$2}' debian/gbp.conf)
-#GIT_TAG := $(subst ~,_,$(VERSION))
-
-# alternatively to manually set those variables you can
-# include /usr/share/cdbs/1/rules/buildvars.mk
-# and use what is set there. Any hint whether dh might set variables in
-# a similar manner are welcome.
-
-%:
- dh $@
-
-#get-orig-source:
-# . debian/get-orig-source
diff --git a/debian/source/format b/debian/source/format
deleted file mode 100644
index 163aaf8..0000000
--- a/debian/source/format
+++ /dev/null
@@ -1 +0,0 @@
-3.0 (quilt)
diff --git a/debian/unc-fish-tests.README.Debian b/debian/unc-fish-tests.README.Debian
deleted file mode 100644
index 7a5d1a5..0000000
--- a/debian/unc-fish-tests.README.Debian
+++ /dev/null
@@ -1,9 +0,0 @@
-Test data for package fish
-==========================
-
-The data are installed at
-
- /var/lib/fish
-
-See the file SAMPLE.txt there for more instructions.
-
diff --git a/debian/unc-fish-tests.install b/debian/unc-fish-tests.install
deleted file mode 100644
index 0109b08..0000000
--- a/debian/unc-fish-tests.install
+++ /dev/null
@@ -1,2 +0,0 @@
-SAMPLES.txt var/lib/fish
-sample_* var/lib/fish
diff --git a/debian/unc-fish.1 b/debian/unc-fish.1
deleted file mode 100644
index 01e3ef0..0000000
--- a/debian/unc-fish.1
+++ /dev/null
@@ -1,42 +0,0 @@
-.TH UNC-FISH "1" "February 2014" "unc-fish 1.0+dfsg" "User Commands"
-.SH NAME
-unc-fish \- Fast Identification of Segmental Homology
-.SH SYNOPSIS
-.B fish
-[\-f Control_File |control.txt]
-.SH DESCRIPTION
-The program unc-fish was originalled named FISH and is a
-software for identifying regions of common ancestry between
-genome maps. Fast identification and statistical evaluation of
-segmental homologies in comparative maps.
-.SH OPTIONS
-.TP
-\fI\-b\fR Block_File
-.TP
-\fI\-g\fR Grid_File
-.TP
-\fI\-C\fR Contig_File
-.TP
-\fI\-D\fR Max_Distance [default=10]
-.TP
-\fI\-S\fR Min_Score [default=200]
-.TP
-\fI\-T\fR Threshold [default=.05]
-.TP
-\fI\-m\fR Min_Block_Size [default=3]
-.TP
-\fI\-off\fR Turn off Detandemize
-.TP
-\fI\-h\fR help
-.TP
-\fI\-H\fR Top_Hits [default=5]
-.TP
-\fI\-A\fR Average_Score Selection [default=Max_Score]
-.TP
-\fI\-p\fR BLOCK_PROB [default=.001]
-.TP
-\fI\-B\fR Block_File_Simple
-.TP
-\fI\-q\fR QUIET_MODE
-.TP
-\fI\-t\fR Print timing
diff --git a/debian/unc-fish.README.Debian b/debian/unc-fish.README.Debian
deleted file mode 100644
index 2d0a711..0000000
--- a/debian/unc-fish.README.Debian
+++ /dev/null
@@ -1,13 +0,0 @@
-FISH for Debian
-===============
-
-Please note: Since there is a package fish in Debian we needed to
-rename the package as well as the executable to unc-fish. If you
-need to use the exectuatble name `fish` somewhere in your scripts
-you can do so by setting
-
- export PATH=/usr/lib/unc-fish:$PATH
-
-since the unrenamed executable resides in /usr/lib/unc-fish.
-
- -- Andreas Tille <tille at debian.org> Fri, 14 Feb 2014 09:23:04 +0100
diff --git a/debian/unc-fish.install b/debian/unc-fish.install
deleted file mode 100644
index 6750054..0000000
--- a/debian/unc-fish.install
+++ /dev/null
@@ -1 +0,0 @@
-src/fish usr/lib/unc-fish
diff --git a/debian/unc-fish.links b/debian/unc-fish.links
deleted file mode 100644
index 607a830..0000000
--- a/debian/unc-fish.links
+++ /dev/null
@@ -1 +0,0 @@
-usr/lib/unc-fish/fish usr/bin/unc-fish
diff --git a/debian/upstream/metadata b/debian/upstream/metadata
deleted file mode 100644
index 1617605..0000000
--- a/debian/upstream/metadata
+++ /dev/null
@@ -1,12 +0,0 @@
-Reference:
- Author: Peter P. Calabrese and Sugata Chakravarty and Todd J. Vision
- Title: Fast identification and statistical evaluation of segmental homologies in comparative maps
- Journal: Bioinformatics
- Year: 2003
- Volume: 19
- Number: Suppl 1
- Pages: i74-i80
- DOI: 10.1093/bioinformatics/btg1008
- PMID: 12855440
- URL: http://bioinformatics.oxfordjournals.org/content/19/suppl_1/i74
- eprint: http://bioinformatics.oxfordjournals.org/content/19/suppl_1/i74.full.pdf+html
diff --git a/debian/watch b/debian/watch
deleted file mode 100644
index 1c1cd5c..0000000
--- a/debian/watch
+++ /dev/null
@@ -1,3 +0,0 @@
-version=3
-opts=dversionmangle=s/\+dfsg// \
- http://labs.bio.unc.edu/Vision/FISH/ .*/vision/lab/FISH/FISH-([\d.]+)-src\.tar\.z
diff --git a/docs/fishmanual.pdf b/docs/fishmanual.pdf
new file mode 100644
index 0000000..58c69a7
Binary files /dev/null and b/docs/fishmanual.pdf differ
diff --git a/docs/fishmanual/WARNINGS b/docs/fishmanual/WARNINGS
new file mode 100644
index 0000000..4b3c1b0
--- /dev/null
+++ b/docs/fishmanual/WARNINGS
@@ -0,0 +1,3 @@
+No implementation found for style `url'
+
+? brace missing for \setlength
diff --git a/docs/fishmanual/fishmanual.css b/docs/fishmanual/fishmanual.css
new file mode 100644
index 0000000..d1824af
--- /dev/null
+++ b/docs/fishmanual/fishmanual.css
@@ -0,0 +1,30 @@
+/* Century Schoolbook font is very similar to Computer Modern Math: cmmi */
+.MATH { font-family: "Century Schoolbook", serif; }
+.MATH I { font-family: "Century Schoolbook", serif; font-style: italic }
+.BOLDMATH { font-family: "Century Schoolbook", serif; font-weight: bold }
+
+/* implement both fixed-size and relative sizes */
+SMALL.XTINY { font-size : xx-small }
+SMALL.TINY { font-size : x-small }
+SMALL.SCRIPTSIZE { font-size : smaller }
+SMALL.FOOTNOTESIZE { font-size : small }
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+BIG.XXLARGE { font-size : x-large }
+BIG.HUGE { font-size : larger }
+BIG.XHUGE { font-size : xx-large }
+
+/* heading styles */
+H1 { }
+H2 { }
+H3 { }
+H4 { }
+H5 { }
+
+/* mathematics styles */
+DIV.displaymath { } /* math displays */
+TD.eqno { } /* equation-number cells */
+
+
+/* document-specific styles come next */
diff --git a/docs/fishmanual/fishmanual.html b/docs/fishmanual/fishmanual.html
new file mode 100644
index 0000000..66edbb6
--- /dev/null
+++ b/docs/fishmanual/fishmanual.html
@@ -0,0 +1,197 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>User's Manual for FISH
+(Fast Identification of Segmental Homology)</TITLE>
+<META NAME="description" CONTENT="User's Manual for FISH
+(Fast Identification of Segmental Homology)">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
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+
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+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="next" HREF="node1.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html4"
+ HREF="node1.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
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+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html5"
+ HREF="node1.html">Contents</A>
+   <B> <A NAME="tex2html3"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H1 ALIGN=CENTER>User's Manual for FISH
+<BR>(Fast Identification of Segmental Homology)</H1>
+<P ALIGN=CENTER><STRONG>version 1.0
+<BR>
+released 30 June 2003
+<BR>
+Copyright 2003 University of North Carolina at Chapel Hill</STRONG></P>
+<P ALIGN=LEFT></P>
+
+<BR><HR>
+<!--Table of Child-Links-->
+<A NAME="CHILD_LINKS"></A>
+
+<UL>
+<LI><A NAME="tex2html6"
+ HREF="node1.html">Contents</A>
+<LI><A NAME="tex2html7"
+ HREF="node2.html">Getting started</A>
+<UL>
+<LI><A NAME="tex2html8"
+ HREF="node3.html">Introduction</A>
+<LI><A NAME="tex2html9"
+ HREF="node4.html">Contact information</A>
+<LI><A NAME="tex2html10"
+ HREF="node5.html">Legal information</A>
+<LI><A NAME="tex2html11"
+ HREF="node6.html">Acknowledgements</A>
+<LI><A NAME="tex2html12"
+ HREF="node7.html">Availability</A>
+<UL>
+<LI><A NAME="tex2html13"
+ HREF="node8.html">Installing from source code</A>
+<LI><A NAME="tex2html14"
+ HREF="node9.html">Installing the Windows executable</A>
+<LI><A NAME="tex2html15"
+ HREF="node10.html">Installing the MacOSX executable</A>
+<LI><A NAME="tex2html16"
+ HREF="node11.html">Testing FISH on sample data</A>
+</UL>
+</UL>
+<BR>
+<LI><A NAME="tex2html17"
+ HREF="node12.html">How it works</A>
+<UL>
+<LI><A NAME="tex2html18"
+ HREF="node13.html">Step 1: From markers to features </A>
+<LI><A NAME="tex2html19"
+ HREF="node14.html">Step 2: From features to grid </A>
+<UL>
+<LI><A NAME="tex2html20"
+ HREF="node15.html">Removing low ranking matches</A>
+<LI><A NAME="tex2html21"
+ HREF="node16.html">Numbering of points</A>
+<LI><A NAME="tex2html22"
+ HREF="node17.html">Enforcing symmetry</A>
+<LI><A NAME="tex2html23"
+ HREF="node18.html">Defining the neighborhood size</A>
+</UL>
+<LI><A NAME="tex2html24"
+ HREF="node19.html">Step 3: From grid to blocks </A>
+<UL>
+<LI><A NAME="tex2html25"
+ HREF="node20.html">Choosing among multiple neighbors</A>
+<LI><A NAME="tex2html26"
+ HREF="node21.html">Overlapping blocks</A>
+</UL>
+</UL>
+<BR>
+<LI><A NAME="tex2html27"
+ HREF="node22.html">Parameters</A>
+<UL>
+<LI><A NAME="tex2html28"
+ HREF="node23.html">Algorithmic parameters </A>
+<LI><A NAME="tex2html29"
+ HREF="node24.html">Input and output parameters </A>
+</UL>
+<BR>
+<LI><A NAME="tex2html30"
+ HREF="node25.html">File formats </A>
+<UL>
+<LI><A NAME="tex2html31"
+ HREF="node26.html">Input files</A>
+<UL>
+<LI><A NAME="tex2html32"
+ HREF="node27.html">Control file </A>
+<LI><A NAME="tex2html33"
+ HREF="node28.html">Map files </A>
+<LI><A NAME="tex2html34"
+ HREF="node29.html">Match files </A>
+</UL>
+<LI><A NAME="tex2html35"
+ HREF="node30.html">Output</A>
+<UL>
+<LI><A NAME="tex2html36"
+ HREF="node31.html">Screen output </A>
+<UL>
+<LI><A NAME="tex2html37"
+ HREF="node32.html">Processing contigs</A>
+<LI><A NAME="tex2html38"
+ HREF="node33.html">Processing matches</A>
+<LI><A NAME="tex2html39"
+ HREF="node34.html">Processing blocks</A>
+</UL>
+<LI><A NAME="tex2html40"
+ HREF="node35.html">Contig file </A>
+<LI><A NAME="tex2html41"
+ HREF="node36.html">Grid file </A>
+<LI><A NAME="tex2html42"
+ HREF="node37.html">Block file </A>
+<LI><A NAME="tex2html43"
+ HREF="node38.html">Simple block file</A>
+</UL>
+</UL>
+<BR>
+<LI><A NAME="tex2html44"
+ HREF="node39.html">An example </A>
+<UL>
+<LI><A NAME="tex2html45"
+ HREF="node40.html">A control input file</A>
+<LI><A NAME="tex2html46"
+ HREF="node41.html">A map input file</A>
+<LI><A NAME="tex2html47"
+ HREF="node42.html">A match input file</A>
+<LI><A NAME="tex2html48"
+ HREF="node43.html">An example of captured STDOUT</A>
+<LI><A NAME="tex2html49"
+ HREF="node44.html">A contig output file</A>
+<LI><A NAME="tex2html50"
+ HREF="node45.html">A grids output file</A>
+<LI><A NAME="tex2html51"
+ HREF="node46.html">A blocks file</A>
+</UL>
+<BR>
+<LI><A NAME="tex2html52"
+ HREF="node47.html">Bibliography</A>
+<LI><A NAME="tex2html53"
+ HREF="node48.html">About this document ...</A>
+</UL>
+<!--End of Table of Child-Links-->
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
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+l2hSize :tex2html_wrap_inline1136:9.5pt::9.5pt::6.60005pt.
+[30
+
+
+] (images.aux) )
+Here is how much of TeX's memory you used:
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+ 15480 string characters out of 196241
+ 62032 words of memory out of 350001
+ 4321 multiletter control sequences out of 10000+15000
+ 8571 words of font info for 29 fonts, out of 400000 for 1000
+ 14 hyphenation exceptions out of 10000
+ 27i,10n,20p,224b,237s stack positions out of 3000i,100n,1500p,50000b,4000s
+
+Output written on images.dvi (30 pages, 7600 bytes).
diff --git a/docs/fishmanual/images.pl b/docs/fishmanual/images.pl
new file mode 100644
index 0000000..8fead7a
--- /dev/null
+++ b/docs/fishmanual/images.pl
@@ -0,0 +1,187 @@
+# LaTeX2HTML 2002 (1.62)
+# Associate images original text with physical files.
+
+
+$key = q/h=mslashn;MSF=1.6;LFS=12;AAT/;
+$cached_env_img{$key} = q|<IMG
+ WIDTH="78" HEIGHT="37" ALIGN="MIDDLE" BORDER="0"
+ SRC="|."$dir".q|img6.png"
+ ALT="$ h=m/n$">|;
+
+$key = q/F;MSF=1.6;LFS=12;AAT/;
+$cached_env_img{$key} = q|<IMG
+ WIDTH="20" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="|."$dir".q|img22.png"
+ ALT="$ F$">|;
+
+$key = q/displaystyled_T=frac{1}{2}+sqrt{frac{{log}(1-T)}{{log}(1-h)}}+frac{1}{4};MSF=1.6;LFS=12;AAT/;
+$cached_env_img{$key} = q|<IMG
+ WIDTH="230" HEIGHT="80" ALIGN="MIDDLE" BORDER="0"
+ SRC="|."$dir".q|img11.png"
+ ALT="$\displaystyle d_T = \frac{1}{2}+\sqrt{\frac{{\log}(1-T)}{{\log}(1-h)}}+\frac{1}{4}$">|;
+
+$key = q/>;MSF=1.6;LFS=12;AAT/;
+$cached_env_img{$key} = q|<IMG
+ WIDTH="19" HEIGHT="34" ALIGN="MIDDLE" BORDER="0"
+ SRC="|."$dir".q|img20.png"
+ ALT="$ >$">|;
+
+$key = q/p;MSF=1.6;LFS=12;AAT/;
+$cached_env_img{$key} = q|<IMG
+ WIDTH="14" HEIGHT="34" ALIGN="MIDDLE" BORDER="0"
+ SRC="|."$dir".q|img25.png"
+ ALT="$ p$">|;
+
+$key = q/(X_j,Y_j);MSF=1.6;LFS=12;AAT/;
+$cached_env_img{$key} = q|<IMG
+ WIDTH="68" HEIGHT="37" ALIGN="MIDDLE" BORDER="0"
+ SRC="|."$dir".q|img9.png"
+ ALT="$ (X_j, Y_j)$">|;
+
+$key = q/N;MSF=1.6;LFS=12;AAT/;
+$cached_env_img{$key} = q|<IMG
+ WIDTH="22" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="|."$dir".q|img21.png"
+ ALT="$ N$">|;
+
+$key = q/p_u=h(nh)^{k-1};MSF=1.6;LFS=12;AAT/;
+$cached_env_img{$key} = q|<IMG
+ WIDTH="121" HEIGHT="40" ALIGN="MIDDLE" BORDER="0"
+ SRC="|."$dir".q|img28.png"
+ ALT="$ p_u = h(nh)^{k-1}$">|;
+
+$key = q/m;MSF=1.6;LFS=12;AAT/;
+$cached_env_img{$key} = q|<IMG
+ WIDTH="21" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="|."$dir".q|img4.png"
+ ALT="$ m$">|;
+
+$key = q/d=|X_i-X_j|+|Y_j-Y_i|;MSF=1.6;LFS=12;AAT/;
+$cached_env_img{$key} = q|<IMG
+ WIDTH="208" HEIGHT="37" ALIGN="MIDDLE" BORDER="0"
+ SRC="|."$dir".q|img10.png"
+ ALT="$ d = \vert X_i - X_j\vert + \vert Y_j - Y_i\vert$">|;
+
+$key = q/i;MSF=1.6;LFS=12;AAT/;
+$cached_env_img{$key} = q|<IMG
+ WIDTH="11" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="|."$dir".q|img1.png"
+ ALT="$ i$">|;
+
+$key = q/F(F-1)slash2;MSF=1.6;LFS=12;AAT/;
+$cached_env_img{$key} = q|<IMG
+ WIDTH="100" HEIGHT="37" ALIGN="MIDDLE" BORDER="0"
+ SRC="|."$dir".q|img23.png"
+ ALT="$ F(F-1)/2$">|;
+
+$key = q/d_c;MSF=1.6;LFS=12;AAT/;
+$cached_env_img{$key} = q|<IMG
+ WIDTH="21" HEIGHT="34" ALIGN="MIDDLE" BORDER="0"
+ SRC="|."$dir".q|img14.png"
+ ALT="$ d_c$">|;
+
+$key = q/displaystylew={cases}1&text{ifthepointisthefirstintheblock},0.25&text{ifaninversionisimpliedbytheextension},0.75&text{otherwise}.{cases};MSF=1.6;LFS=12;AAT/;
+$cached_env_img{$key} = q|<IMG
+ WIDTH="440" HEIGHT="101" ALIGN="MIDDLE" BORDER="0"
+ SRC="|."$dir".q|img16.png"
+ ALT="$\displaystyle w = \begin{cases}1 & \text{if the point is the first in the block...
+... inversion is implied by the extension},\ 0.75 & \text{otherwise}. \end{cases}$">|;
+
+$key = q/(X_i,Y_i);MSF=1.6;LFS=12;AAT/;
+$cached_env_img{$key} = q|<IMG
+ WIDTH="65" HEIGHT="37" ALIGN="MIDDLE" BORDER="0"
+ SRC="|."$dir".q|img8.png"
+ ALT="$ (X_i, Y_i)$">|;
+
+$key = q/j;MSF=1.6;LFS=12;AAT/;
+$cached_env_img{$key} = q|<IMG
+ WIDTH="14" HEIGHT="34" ALIGN="MIDDLE" BORDER="0"
+ SRC="|."$dir".q|img2.png"
+ ALT="$ j$">|;
+
+$key = q/displaystylep=1-e^{-rcp_u};MSF=1.6;LFS=12;AAT/;
+$cached_env_img{$key} = q|<IMG
+ WIDTH="119" HEIGHT="39" ALIGN="MIDDLE" BORDER="0"
+ SRC="|."$dir".q|img26.png"
+ ALT="$\displaystyle p = 1-e^{-rc p_u}$">|;
+
+$key = q/displaystyler=wfrac{1slashd_c}{sum_{1}^{n}(1slashd_c)};MSF=1.6;LFS=12;AAT/;
+$cached_env_img{$key} = q|<IMG
+ WIDTH="135" HEIGHT="62" ALIGN="MIDDLE" BORDER="0"
+ SRC="|."$dir".q|img13.png"
+ ALT="$\displaystyle r = w \frac{1/d_c}{\sum_{1}^{n}(1/d_c)}$">|;
+
+$key = q/n;MSF=1.6;LFS=12;AAT/;
+$cached_env_img{$key} = q|<IMG
+ WIDTH="16" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="|."$dir".q|img5.png"
+ ALT="$ n$">|;
+
+$key = q/igeqj;MSF=1.6;LFS=12;AAT/;
+$cached_env_img{$key} = q|<IMG
+ WIDTH="45" HEIGHT="34" ALIGN="MIDDLE" BORDER="0"
+ SRC="|."$dir".q|img3.png"
+ ALT="$ i \geq j$">|;
+
+$key = q/w;MSF=1.6;LFS=12;AAT/;
+$cached_env_img{$key} = q|<IMG
+ WIDTH="19" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="|."$dir".q|img15.png"
+ ALT="$ w$">|;
+
+$key = q/d_T;MSF=1.6;LFS=12;AAT/;
+$cached_env_img{$key} = q|<IMG
+ WIDTH="25" HEIGHT="34" ALIGN="MIDDLE" BORDER="0"
+ SRC="|."$dir".q|img18.png"
+ ALT="$ d_T$">|;
+
+$key = q/L;MSF=1.6;LFS=12;AAT/;
+$cached_env_img{$key} = q|<IMG
+ WIDTH="17" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="|."$dir".q|img24.png"
+ ALT="$ L$">|;
+
+$key = q/r;MSF=1.6;LFS=12;AAT/;
+$cached_env_img{$key} = q|<IMG
+ WIDTH="14" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="|."$dir".q|img12.png"
+ ALT="$ r$">|;
+
+$key = q/backslash;MSF=1.6;LFS=12;AAT/;
+$cached_env_img{$key} = q|<IMG
+ WIDTH="14" HEIGHT="37" ALIGN="MIDDLE" BORDER="0"
+ SRC="|."$dir".q|img30.png"
+ ALT="$ \backslash$">|;
+
+$key = q/h;MSF=1.6;LFS=12;AAT/;
+$cached_env_img{$key} = q|<IMG
+ WIDTH="16" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="|."$dir".q|img19.png"
+ ALT="$ h$">|;
+
+$key = q/slash;MSF=1.6;LFS=12;AAT/;
+$cached_env_img{$key} = q|<IMG
+ WIDTH="5" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="|."$dir".q|img29.png"
+ ALT="$ \/$">|;
+
+$key = q/|(|X_i-X_j|)-(|Y_j-Y_i|)|;MSF=1.6;LFS=12;AAT/;
+$cached_env_img{$key} = q|<IMG
+ WIDTH="213" HEIGHT="37" ALIGN="MIDDLE" BORDER="0"
+ SRC="|."$dir".q|img17.png"
+ ALT="$ \vert(\vert X_i - X_j\vert)-(\vert Y_j - Y_i\vert)\vert$">|;
+
+$key = q/rc;MSF=1.6;LFS=12;AAT/;
+$cached_env_img{$key} = q|<IMG
+ WIDTH="22" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="|."$dir".q|img27.png"
+ ALT="$ rc$">|;
+
+$key = q/T;MSF=1.6;LFS=12;AAT/;
+$cached_env_img{$key} = q|<IMG
+ WIDTH="18" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="|."$dir".q|img7.png"
+ ALT="$ T$">|;
+
+1;
+
diff --git a/docs/fishmanual/images.tex b/docs/fishmanual/images.tex
new file mode 100644
index 0000000..dd6e685
--- /dev/null
+++ b/docs/fishmanual/images.tex
@@ -0,0 +1,381 @@
+\batchmode
+
+
+\documentclass[notitlepage,twoside,12pt]{report}
+\RequirePackage{ifthen}
+
+
+\usepackage{times}
+\usepackage{url}
+\usepackage{amsmath}
+\pagestyle{headings}
+
+
+
+\usepackage[dvips]{color}
+
+
+\pagecolor[gray]{.7}
+
+\usepackage[latin1]{inputenc}
+
+
+
+\makeatletter
+
+\makeatletter
+\count@=\the\catcode`\_ \catcode`\_=8
+\newenvironment{tex2html_wrap}{}{}%
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+\newcommand{\providedcommand}[1]{\expandafter\providecommand\csname #1\endcsname}%
+\newcommand{\renewedcommand}[1]{\expandafter\providecommand\csname #1\endcsname{}%
+ \expandafter\renewcommand\csname #1\endcsname}%
+\newcommand{\newedenvironment}[1]{\newenvironment{#1}{}{}\renewenvironment{#1}}%
+\let\newedcommand\renewedcommand
+\let\renewedenvironment\newedenvironment
+\makeatother
+\let\mathon=$
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+\newbox\sizebox
+\setlength{\hoffset}{0pt}\setlength{\voffset}{0pt}
+\addtolength{\textheight}{\footskip}\setlength{\footskip}{0pt}
+\addtolength{\textheight}{\topmargin}\setlength{\topmargin}{0pt}
+\addtolength{\textheight}{\headheight}\setlength{\headheight}{0pt}
+\addtolength{\textheight}{\headsep}\setlength{\headsep}{0pt}
+\setlength{\textwidth}{349pt}
+\newwrite\lthtmlwrite
+\makeatletter
+\let\realnormalsize=\normalsize
+\global\topskip=2sp
+\def\preveqno{}\let\real at float=\@float \let\realend at float=\end at float
+\def\@float{\let\@savefreelist\@freelist\real at float}
+\def\liih at math{\ifmmode$\else\bad at math\fi}
+\def\end at float{\realend at float\global\let\@freelist\@savefreelist}
+\let\real at dbflt=\@dbflt \let\end at dblfloat=\end at float
+\let\@largefloatcheck=\relax
+\let\if at boxedmulticols=\iftrue
+\def\@dbflt{\let\@savefreelist\@freelist\real at dbflt}
+\def\adjustnormalsize{\def\normalsize{\mathsurround=0pt \realnormalsize
+ \parindent=0pt\abovedisplayskip=0pt\belowdisplayskip=0pt}%
+ \def\phantompar{\csname par\endcsname}\normalsize}%
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+\newcommand\lthtmlhboxmathA{\adjustnormalsize\setbox\sizebox=\hbox\bgroup\kern.05em }%
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+ \let\ifinner=\iffalse \let\)\liih at math }%
+\newcommand\lthtmlboxmathZ{\@next\next\@currlist{}{\def\next{\voidb at x}}%
+ \expandafter\box\next\egroup}%
+\newcommand\lthtmlmathtype[1]{\gdef\lthtmlmathenv{#1}}%
+\newcommand\lthtmllogmath{\lthtmltypeout{l2hSize %
+:\lthtmlmathenv:\the\ht\sizebox::\the\dp\sizebox::\the\wd\sizebox.\preveqno}}%
+\newcommand\lthtmlfigureA[1]{\let\@savefreelist\@freelist
+ \lthtmlmathtype{#1}\lthtmlvboxmathA}%
+\newcommand\lthtmlpictureA{\bgroup\catcode`\_=8 \lthtmlpictureB}%
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+ \let\@savefreelist\@freelist \lthtmlhboxmathB}%
+\newcommand\lthtmlpictureZ[1]{\hfill\lthtmlfigureZ}%
+\newcommand\lthtmlfigureZ{\lthtmlboxmathZ\lthtmllogmath\copy\sizebox
+ \global\let\@freelist\@savefreelist}%
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+\newcommand\lthtmldisplayAi[1]{\lthtmlmathtype{#1}\egroup\lthtmlvboxmathA}%
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+ \lthtmldisplayA{#1}\let\@eqnnum\relax}%
+\newcommand\lthtmldisplayZ{\lthtmlboxmathZ\lthtmllogmath\lthtmlsetmath}%
+\newcommand\lthtmlinlinemathA{\bgroup\catcode`\_=8 \lthtmlinlinemathB}
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+\newcommand\lthtmlinlineZ{\egroup\expandafter\ifdim\dp\sizebox>0pt %
+ \expandafter\centerinlinemath\fi\lthtmllogmath\lthtmlsetinline}
+\newcommand\lthtmlinlinemathZ{\egroup\expandafter\ifdim\dp\sizebox>0pt %
+ \expandafter\centerinlinemath\fi\lthtmllogmath\lthtmlsetmath}
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+ \ifdim\hsize>\wd\sizebox \hrule depth1pt\fi}}}
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+ \ifdim\dp\sizebox>0pt\kern.1em\fi \kern0.8 pt%
+ \ifdim\hsize>\wd\sizebox \hrule depth1pt\fi}}}
+\def\centerinlinemath{%
+ \dimen1=\ifdim\ht\sizebox<\dp\sizebox \dp\sizebox\else\ht\sizebox\fi
+ \advance\dimen1by.5pt \vrule width0pt height\dimen1 depth\dimen1
+ \dp\sizebox=\dimen1\ht\sizebox=\dimen1\relax}
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+\def\lthtmlcheckvsize{\ifdim\ht\sizebox<\vsize
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+\providecommand{\selectlanguage}[1]{}%
+\makeatletter \tracingstats = 1
+\providecommand{\Beta}{\textrm{B}}
+\providecommand{\Mu}{\textrm{M}}
+\providecommand{\Kappa}{\textrm{K}}
+\providecommand{\Rho}{\textrm{R}}
+\providecommand{\Epsilon}{\textrm{E}}
+\providecommand{\Chi}{\textrm{X}}
+\providecommand{\Iota}{\textrm{J}}
+\providecommand{\omicron}{\textrm{o}}
+\providecommand{\Zeta}{\textrm{Z}}
+\providecommand{\Eta}{\textrm{H}}
+\providecommand{\Omicron}{\textrm{O}}
+\providecommand{\Nu}{\textrm{N}}
+\providecommand{\Tau}{\textrm{T}}
+\providecommand{\Alpha}{\textrm{A}}
+
+
+\begin{document}
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+\lthtmltypeout{latex2htmlLength hsize=\the\hsize}\lthtmltypeout{}%
+\lthtmltypeout{latex2htmlLength vsize=\the\vsize}\lthtmltypeout{}%
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+\lthtmltypeout{latex2htmlLength headheight=\the\headheight}\lthtmltypeout{}%
+\lthtmltypeout{latex2htmlLength headsep=\the\headsep}\lthtmltypeout{}%
+\lthtmltypeout{latex2htmlLength parskip=\the\parskip}\lthtmltypeout{}%
+\lthtmltypeout{latex2htmlLength oddsidemargin=\the\oddsidemargin}\lthtmltypeout{}%
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+\lthtmltypeout{}%
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+% !!! IMAGES START HERE !!!
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+\stepcounter{chapter}
+
+\setlength%
+
+\setlength{}{}
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+$ i$%
+\lthtmlinlinemathZ
+\lthtmlcheckvsize\clearpage}
+
+{\newpage\clearpage
+\lthtmlinlinemathA{tex2html_wrap_inline929}%
+$ j$%
+\lthtmlinlinemathZ
+\lthtmlcheckvsize\clearpage}
+
+\stepcounter{subsection}
+\stepcounter{subsection}
+{\newpage\clearpage
+\lthtmlinlinemathA{tex2html_wrap_inline933}%
+$ i \geq j$%
+\lthtmlinlinemathZ
+\lthtmlcheckvsize\clearpage}
+
+\stepcounter{subsection}
+\stepcounter{subsection}
+{\newpage\clearpage
+\lthtmlinlinemathA{tex2html_wrap_inline949}%
+$ m$%
+\lthtmlinlinemathZ
+\lthtmlcheckvsize\clearpage}
+
+{\newpage\clearpage
+\lthtmlinlinemathA{tex2html_wrap_inline951}%
+$ n$%
+\lthtmlinlinemathZ
+\lthtmlcheckvsize\clearpage}
+
+{\newpage\clearpage
+\lthtmlinlinemathA{tex2html_wrap_inline953}%
+$ h=m/n$%
+\lthtmlinlinemathZ
+\lthtmlcheckvsize\clearpage}
+
+{\newpage\clearpage
+\lthtmlinlinemathA{tex2html_wrap_inline955}%
+$ T$%
+\lthtmlinlinemathZ
+\lthtmlcheckvsize\clearpage}
+
+{\newpage\clearpage
+\lthtmlinlinemathA{tex2html_wrap_inline957}%
+$ (X_i, Y_i)$%
+\lthtmlinlinemathZ
+\lthtmlcheckvsize\clearpage}
+
+{\newpage\clearpage
+\lthtmlinlinemathA{tex2html_wrap_inline959}%
+$ (X_j, Y_j)$%
+\lthtmlinlinemathZ
+\lthtmlcheckvsize\clearpage}
+
+{\newpage\clearpage
+\lthtmlinlinemathA{tex2html_wrap_inline961}%
+$ d = |X_i - X_j| + |Y_j - Y_i|$%
+\lthtmlinlinemathZ
+\lthtmlcheckvsize\clearpage}
+
+{\newpage\clearpage
+\lthtmlinlinemathA{tex2html_wrap_indisplay963}%
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+\lthtmlindisplaymathZ
+\lthtmlcheckvsize\clearpage}
+
+\stepcounter{section}
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+{\newpage\clearpage
+\lthtmlinlinemathA{tex2html_wrap_inline967}%
+$ r$%
+\lthtmlinlinemathZ
+\lthtmlcheckvsize\clearpage}
+
+{\newpage\clearpage
+\lthtmlinlinemathA{tex2html_wrap_indisplay969}%
+$\displaystyle r = w \frac{1/d_c}{\sum_{1}^{n}(1/d_c)}$%
+\lthtmlindisplaymathZ
+\lthtmlcheckvsize\clearpage}
+
+{\newpage\clearpage
+\lthtmlinlinemathA{tex2html_wrap_inline973}%
+$ d_c$%
+\lthtmlinlinemathZ
+\lthtmlcheckvsize\clearpage}
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+{\newpage\clearpage
+\lthtmlinlinemathA{tex2html_wrap_inline975}%
+$ w$%
+\lthtmlinlinemathZ
+\lthtmlcheckvsize\clearpage}
+
+{\newpage\clearpage
+\lthtmlinlinemathA{tex2html_wrap_indisplay977}%
+$\displaystyle w = \begin{cases} 1 & \text{if the point is the first in the block},\\0.25 & \text{if an inversion is implied by the extension},\\0.75 & \text{otherwise}. \end{cases}$%
+\lthtmlindisplaymathZ
+\lthtmlcheckvsize\clearpage}
+
+{\newpage\clearpage
+\lthtmlinlinemathA{tex2html_wrap_inline979}%
+$ |(|X_i - X_j|)-(|Y_j - Y_i|)|$%
+\lthtmlinlinemathZ
+\lthtmlcheckvsize\clearpage}
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+\stepcounter{subsection}
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+$ d_T$%
+\lthtmlinlinemathZ
+\lthtmlcheckvsize\clearpage}
+
+{\newpage\clearpage
+\lthtmlinlinemathA{tex2html_wrap_inline1057}%
+$ h$%
+\lthtmlinlinemathZ
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+\stepcounter{section}
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+{\newpage\clearpage
+\lthtmlinlinemathA{tex2html_wrap_inline1081}%
+$ >$%
+\lthtmlinlinemathZ
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+LaTeX2HTML 2002 (1.62),
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+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>User's Manual for FISH
+(Fast Identification of Segmental Homology)</TITLE>
+<META NAME="description" CONTENT="User's Manual for FISH
+(Fast Identification of Segmental Homology)">
+<META NAME="keywords" CONTENT="fishmanual">
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+<BR>
+<B> Next:</B> <A NAME="tex2html5"
+ HREF="node1.html">Contents</A>
+   <B> <A NAME="tex2html3"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H1 ALIGN=CENTER>User's Manual for FISH
+<BR>(Fast Identification of Segmental Homology)</H1>
+<P ALIGN=CENTER><STRONG>version 1.0
+<BR>
+released 30 June 2003
+<BR>
+Copyright 2003 University of North Carolina at Chapel Hill</STRONG></P>
+<P ALIGN=LEFT></P>
+
+<BR><HR>
+<!--Table of Child-Links-->
+<A NAME="CHILD_LINKS"></A>
+
+<UL>
+<LI><A NAME="tex2html6"
+ HREF="node1.html">Contents</A>
+<LI><A NAME="tex2html7"
+ HREF="node2.html">Getting started</A>
+<UL>
+<LI><A NAME="tex2html8"
+ HREF="node3.html">Introduction</A>
+<LI><A NAME="tex2html9"
+ HREF="node4.html">Contact information</A>
+<LI><A NAME="tex2html10"
+ HREF="node5.html">Legal information</A>
+<LI><A NAME="tex2html11"
+ HREF="node6.html">Acknowledgements</A>
+<LI><A NAME="tex2html12"
+ HREF="node7.html">Availability</A>
+<UL>
+<LI><A NAME="tex2html13"
+ HREF="node8.html">Installing from source code</A>
+<LI><A NAME="tex2html14"
+ HREF="node9.html">Installing the Windows executable</A>
+<LI><A NAME="tex2html15"
+ HREF="node10.html">Installing the MacOSX executable</A>
+<LI><A NAME="tex2html16"
+ HREF="node11.html">Testing FISH on sample data</A>
+</UL>
+</UL>
+<BR>
+<LI><A NAME="tex2html17"
+ HREF="node12.html">How it works</A>
+<UL>
+<LI><A NAME="tex2html18"
+ HREF="node13.html">Step 1: From markers to features </A>
+<LI><A NAME="tex2html19"
+ HREF="node14.html">Step 2: From features to grid </A>
+<UL>
+<LI><A NAME="tex2html20"
+ HREF="node15.html">Removing low ranking matches</A>
+<LI><A NAME="tex2html21"
+ HREF="node16.html">Numbering of points</A>
+<LI><A NAME="tex2html22"
+ HREF="node17.html">Enforcing symmetry</A>
+<LI><A NAME="tex2html23"
+ HREF="node18.html">Defining the neighborhood size</A>
+</UL>
+<LI><A NAME="tex2html24"
+ HREF="node19.html">Step 3: From grid to blocks </A>
+<UL>
+<LI><A NAME="tex2html25"
+ HREF="node20.html">Choosing among multiple neighbors</A>
+<LI><A NAME="tex2html26"
+ HREF="node21.html">Overlapping blocks</A>
+</UL>
+</UL>
+<BR>
+<LI><A NAME="tex2html27"
+ HREF="node22.html">Parameters</A>
+<UL>
+<LI><A NAME="tex2html28"
+ HREF="node23.html">Algorithmic parameters </A>
+<LI><A NAME="tex2html29"
+ HREF="node24.html">Input and output parameters </A>
+</UL>
+<BR>
+<LI><A NAME="tex2html30"
+ HREF="node25.html">File formats </A>
+<UL>
+<LI><A NAME="tex2html31"
+ HREF="node26.html">Input files</A>
+<UL>
+<LI><A NAME="tex2html32"
+ HREF="node27.html">Control file </A>
+<LI><A NAME="tex2html33"
+ HREF="node28.html">Map files </A>
+<LI><A NAME="tex2html34"
+ HREF="node29.html">Match files </A>
+</UL>
+<LI><A NAME="tex2html35"
+ HREF="node30.html">Output</A>
+<UL>
+<LI><A NAME="tex2html36"
+ HREF="node31.html">Screen output </A>
+<UL>
+<LI><A NAME="tex2html37"
+ HREF="node32.html">Processing contigs</A>
+<LI><A NAME="tex2html38"
+ HREF="node33.html">Processing matches</A>
+<LI><A NAME="tex2html39"
+ HREF="node34.html">Processing blocks</A>
+</UL>
+<LI><A NAME="tex2html40"
+ HREF="node35.html">Contig file </A>
+<LI><A NAME="tex2html41"
+ HREF="node36.html">Grid file </A>
+<LI><A NAME="tex2html42"
+ HREF="node37.html">Block file </A>
+<LI><A NAME="tex2html43"
+ HREF="node38.html">Simple block file</A>
+</UL>
+</UL>
+<BR>
+<LI><A NAME="tex2html44"
+ HREF="node39.html">An example </A>
+<UL>
+<LI><A NAME="tex2html45"
+ HREF="node40.html">A control input file</A>
+<LI><A NAME="tex2html46"
+ HREF="node41.html">A map input file</A>
+<LI><A NAME="tex2html47"
+ HREF="node42.html">A match input file</A>
+<LI><A NAME="tex2html48"
+ HREF="node43.html">An example of captured STDOUT</A>
+<LI><A NAME="tex2html49"
+ HREF="node44.html">A contig output file</A>
+<LI><A NAME="tex2html50"
+ HREF="node45.html">A grids output file</A>
+<LI><A NAME="tex2html51"
+ HREF="node46.html">A blocks file</A>
+</UL>
+<BR>
+<LI><A NAME="tex2html52"
+ HREF="node47.html">Bibliography</A>
+<LI><A NAME="tex2html53"
+ HREF="node48.html">About this document ...</A>
+</UL>
+<!--End of Table of Child-Links-->
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
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+$noresave{$key} = "$nosave";
+
+$key = q/paramtable/;
+$external_latex_labels{$key} = q|3|;
+$noresave{$key} = "$nosave";
+
+$key = q/screenoutput/;
+$external_latex_labels{$key} = q|4.2.1|;
+$noresave{$key} = "$nosave";
+
+$key = q/contigfile/;
+$external_latex_labels{$key} = q|4.2.2|;
+$noresave{$key} = "$nosave";
+
+$key = q/gridfile/;
+$external_latex_labels{$key} = q|4.2.3|;
+$noresave{$key} = "$nosave";
+
+$key = q/blockfile/;
+$external_latex_labels{$key} = q|4.2.4|;
+$noresave{$key} = "$nosave";
+
+1;
+
diff --git a/docs/fishmanual/node1.html b/docs/fishmanual/node1.html
new file mode 100644
index 0000000..ac47346
--- /dev/null
+++ b/docs/fishmanual/node1.html
@@ -0,0 +1,188 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Contents</TITLE>
+<META NAME="description" CONTENT="Contents">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="next" HREF="node2.html">
+<LINK REL="previous" HREF="fishmanual.html">
+<LINK REL="up" HREF="fishmanual.html">
+<LINK REL="next" HREF="node2.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html62"
+ HREF="node2.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html60"
+ HREF="fishmanual.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html54"
+ HREF="fishmanual.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html63"
+ HREF="node2.html">Getting started</A>
+<B> Up:</B> <A NAME="tex2html61"
+ HREF="fishmanual.html">User's Manual for FISH</A>
+<B> Previous:</B> <A NAME="tex2html55"
+ HREF="fishmanual.html">User's Manual for FISH</A>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+<BR>
+
+<H2><A NAME="SECTION00100000000000000000">
+Contents</A>
+</H2>
+<!--Table of Contents-->
+
+<UL>
+<LI><A NAME="tex2html64"
+ HREF="node2.html">Getting started</A>
+<UL>
+<LI><A NAME="tex2html65"
+ HREF="node3.html">Introduction</A>
+<LI><A NAME="tex2html66"
+ HREF="node4.html">Contact information</A>
+<LI><A NAME="tex2html67"
+ HREF="node5.html">Legal information</A>
+<LI><A NAME="tex2html68"
+ HREF="node6.html">Acknowledgements</A>
+<LI><A NAME="tex2html69"
+ HREF="node7.html">Availability</A>
+<UL>
+<LI><A NAME="tex2html70"
+ HREF="node8.html">Installing from source code</A>
+<LI><A NAME="tex2html71"
+ HREF="node9.html">Installing the Windows executable</A>
+<LI><A NAME="tex2html72"
+ HREF="node10.html">Installing the MacOSX executable</A>
+<LI><A NAME="tex2html73"
+ HREF="node11.html">Testing FISH on sample data</A>
+</UL>
+</UL>
+<BR>
+<LI><A NAME="tex2html74"
+ HREF="node12.html">How it works</A>
+<UL>
+<LI><A NAME="tex2html75"
+ HREF="node13.html">Step 1: From markers to features </A>
+<LI><A NAME="tex2html76"
+ HREF="node14.html">Step 2: From features to grid </A>
+<UL>
+<LI><A NAME="tex2html77"
+ HREF="node15.html">Removing low ranking matches</A>
+<LI><A NAME="tex2html78"
+ HREF="node16.html">Numbering of points</A>
+<LI><A NAME="tex2html79"
+ HREF="node17.html">Enforcing symmetry</A>
+<LI><A NAME="tex2html80"
+ HREF="node18.html">Defining the neighborhood size</A>
+</UL>
+<LI><A NAME="tex2html81"
+ HREF="node19.html">Step 3: From grid to blocks </A>
+<UL>
+<LI><A NAME="tex2html82"
+ HREF="node20.html">Choosing among multiple neighbors</A>
+<LI><A NAME="tex2html83"
+ HREF="node21.html">Overlapping blocks</A>
+</UL>
+</UL>
+<BR>
+<LI><A NAME="tex2html84"
+ HREF="node22.html">Parameters</A>
+<UL>
+<LI><A NAME="tex2html85"
+ HREF="node23.html">Algorithmic parameters </A>
+<LI><A NAME="tex2html86"
+ HREF="node24.html">Input and output parameters </A>
+</UL>
+<BR>
+<LI><A NAME="tex2html87"
+ HREF="node25.html">File formats </A>
+<UL>
+<LI><A NAME="tex2html88"
+ HREF="node26.html">Input files</A>
+<UL>
+<LI><A NAME="tex2html89"
+ HREF="node27.html">Control file </A>
+<LI><A NAME="tex2html90"
+ HREF="node28.html">Map files </A>
+<LI><A NAME="tex2html91"
+ HREF="node29.html">Match files </A>
+</UL>
+<LI><A NAME="tex2html92"
+ HREF="node30.html">Output</A>
+<UL>
+<LI><A NAME="tex2html93"
+ HREF="node31.html">Screen output </A>
+<LI><A NAME="tex2html94"
+ HREF="node35.html">Contig file </A>
+<LI><A NAME="tex2html95"
+ HREF="node36.html">Grid file </A>
+<LI><A NAME="tex2html96"
+ HREF="node37.html">Block file </A>
+<LI><A NAME="tex2html97"
+ HREF="node38.html">Simple block file</A>
+</UL>
+</UL>
+<BR>
+<LI><A NAME="tex2html98"
+ HREF="node39.html">An example </A>
+<UL>
+<LI><A NAME="tex2html99"
+ HREF="node40.html">A control input file</A>
+<LI><A NAME="tex2html100"
+ HREF="node41.html">A map input file</A>
+<LI><A NAME="tex2html101"
+ HREF="node42.html">A match input file</A>
+<LI><A NAME="tex2html102"
+ HREF="node43.html">An example of captured STDOUT</A>
+<LI><A NAME="tex2html103"
+ HREF="node44.html">A contig output file</A>
+<LI><A NAME="tex2html104"
+ HREF="node45.html">A grids output file</A>
+<LI><A NAME="tex2html105"
+ HREF="node46.html">A blocks file</A>
+</UL>
+<BR>
+<LI><A NAME="tex2html106"
+ HREF="node47.html">Bibliography</A>
+<LI><A NAME="tex2html107"
+ HREF="node48.html">About this document ...</A>
+</UL>
+<!--End of Table of Contents-->
+<DIV ALIGN="LEFT">
+</DIV>
+<P>
+<DIV ALIGN="LEFT">
+</DIV>
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node10.html b/docs/fishmanual/node10.html
new file mode 100644
index 0000000..55669e9
--- /dev/null
+++ b/docs/fishmanual/node10.html
@@ -0,0 +1,80 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Installing the MacOSX executable</TITLE>
+<META NAME="description" CONTENT="Installing the MacOSX executable">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="next" HREF="node11.html">
+<LINK REL="previous" HREF="node9.html">
+<LINK REL="up" HREF="node7.html">
+<LINK REL="next" HREF="node11.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html225"
+ HREF="node11.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html221"
+ HREF="node7.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html215"
+ HREF="node9.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html223"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html226"
+ HREF="node11.html">Testing FISH on sample</A>
+<B> Up:</B> <A NAME="tex2html222"
+ HREF="node7.html">Availability</A>
+<B> Previous:</B> <A NAME="tex2html216"
+ HREF="node9.html">Installing the Windows executable</A>
+   <B> <A NAME="tex2html224"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H2><A NAME="SECTION00253000000000000000">
+Installing the MacOSX executable</A>
+</H2>
+<PRE>
+INSTALLATION:
+ 1. Unzip FISH-1.0-osx.zip.
+ 2. The executable will be located in "FISH-1.0/fish".
+REQUIREMENTS:
+ 1. 32 MB of RAM.
+ 2. Operating system: Known to run on 10.2.x
+</PRE>
+
+<P>
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node11.html b/docs/fishmanual/node11.html
new file mode 100644
index 0000000..df04ea0
--- /dev/null
+++ b/docs/fishmanual/node11.html
@@ -0,0 +1,75 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Testing FISH on sample data</TITLE>
+<META NAME="description" CONTENT="Testing FISH on sample data">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="previous" HREF="node10.html">
+<LINK REL="up" HREF="node7.html">
+<LINK REL="next" HREF="node12.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html235"
+ HREF="node12.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html231"
+ HREF="node7.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html227"
+ HREF="node10.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html233"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html236"
+ HREF="node12.html">How it works</A>
+<B> Up:</B> <A NAME="tex2html232"
+ HREF="node7.html">Availability</A>
+<B> Previous:</B> <A NAME="tex2html228"
+ HREF="node10.html">Installing the MacOSX executable</A>
+   <B> <A NAME="tex2html234"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H2><A NAME="SECTION00254000000000000000">
+Testing FISH on sample data</A>
+</H2>
+You may use the sample files to test that the program is working properly.
+From a command line window, go to the directory within the distribution
+where the sample control file, ``control.txt", is located. Type 'fish', then
+enter, and within a few seconds FISH should complete the analysis.
+
+<P>
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node12.html b/docs/fishmanual/node12.html
new file mode 100644
index 0000000..2b72170
--- /dev/null
+++ b/docs/fishmanual/node12.html
@@ -0,0 +1,124 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>How it works</TITLE>
+<META NAME="description" CONTENT="How it works">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="next" HREF="node22.html">
+<LINK REL="previous" HREF="node2.html">
+<LINK REL="up" HREF="fishmanual.html">
+<LINK REL="next" HREF="node13.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html247"
+ HREF="node13.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html243"
+ HREF="fishmanual.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html237"
+ HREF="node11.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html245"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html248"
+ HREF="node13.html">Step 1: From markers</A>
+<B> Up:</B> <A NAME="tex2html244"
+ HREF="fishmanual.html">User's Manual for FISH</A>
+<B> Previous:</B> <A NAME="tex2html238"
+ HREF="node11.html">Testing FISH on sample</A>
+   <B> <A NAME="tex2html246"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H1><A NAME="SECTION00300000000000000000">
+How it works</A>
+</H1>
+The following is a concise overview of FISH.
+A fuller description of the methodology is given in [<A
+ HREF="node47.html#Calabrese2003">1</A>],
+with which we assume the reader is already familiar.
+There are three steps in the analysis:
+<DL>
+<DT><STRONG>Step 1:</STRONG></DT>
+<DD>From markers to features
+</DD>
+<DT><STRONG>Step 2:</STRONG></DT>
+<DD>From features to grid
+</DD>
+<DT><STRONG>Step 3:</STRONG></DT>
+<DD>From grid to blocks
+</DD>
+</DL>
+Each genome to be compared consists of one or more linear
+contigs, which consist of a sequence of features. A feature is typically one or more
+closely related
+protein-coding genes at a particular locus, but may be any entity to which it is
+possible to ascribe homology to other
+features. Because FISH considers a contig to be merely an ordering of features, it is
+in effect treating the distance between adjacent features as one unit.
+
+<P>
+<BR><HR>
+<!--Table of Child-Links-->
+<A NAME="CHILD_LINKS"><STRONG>Subsections</STRONG></A>
+
+<UL>
+<LI><A NAME="tex2html249"
+ HREF="node13.html">Step 1: From markers to features </A>
+<LI><A NAME="tex2html250"
+ HREF="node14.html">Step 2: From features to grid </A>
+<UL>
+<LI><A NAME="tex2html251"
+ HREF="node15.html">Removing low ranking matches</A>
+<LI><A NAME="tex2html252"
+ HREF="node16.html">Numbering of points</A>
+<LI><A NAME="tex2html253"
+ HREF="node17.html">Enforcing symmetry</A>
+<LI><A NAME="tex2html254"
+ HREF="node18.html">Defining the neighborhood size</A>
+</UL>
+<BR>
+<LI><A NAME="tex2html255"
+ HREF="node19.html">Step 3: From grid to blocks </A>
+<UL>
+<LI><A NAME="tex2html256"
+ HREF="node20.html">Choosing among multiple neighbors</A>
+<LI><A NAME="tex2html257"
+ HREF="node21.html">Overlapping blocks</A>
+</UL></UL>
+<!--End of Table of Child-Links-->
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node13.html b/docs/fishmanual/node13.html
new file mode 100644
index 0000000..0adb233
--- /dev/null
+++ b/docs/fishmanual/node13.html
@@ -0,0 +1,147 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Step 1: From markers to features </TITLE>
+<META NAME="description" CONTENT="Step 1: From markers to features ">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="next" HREF="node14.html">
+<LINK REL="previous" HREF="node12.html">
+<LINK REL="up" HREF="node12.html">
+<LINK REL="next" HREF="node14.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html268"
+ HREF="node14.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html264"
+ HREF="node12.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html258"
+ HREF="node12.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html266"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html269"
+ HREF="node14.html">Step 2: From features</A>
+<B> Up:</B> <A NAME="tex2html265"
+ HREF="node12.html">How it works</A>
+<B> Previous:</B> <A NAME="tex2html259"
+ HREF="node12.html">How it works</A>
+   <B> <A NAME="tex2html267"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H1><A NAME="SECTION00310000000000000000"></A><A NAME="step1"></A>
+<BR>
+Step 1: From markers to features
+</H1>
+The names, positions and transcriptional orientations (when known) of the
+markers are read from a
+set of <I>map files</I>, one map file per contig.
+Markers within each map file must be ordered according to their physical
+positions on the contig. FISH assigns each marker a unique identification
+number,
+from 1 to the total number of markers in all the contigs, which serves as a
+linear coordinate for subsequent calculations.
+Markers cannot appear more than once on a contig, <I>i.e</I> each marker on a
+contig must be unique; otherwise, an error will result.
+
+<P>
+Individual homologies between markers are read from a set of <I>match files</I>. There
+is at least one, and no more than two, such files for each pair of contigs. Each
+match is associated
+with a score that reflects the strength of that match. Larger scores indicate stronger matches.
+When two matches between the same markers are present in two different match files (<I>i.e.</I>
+contig 1 vs contig 2, and contig 2 vs, contig 1), the score is taken to be either the maximum
+or the average of the two according to the user's choice (refer <A HREF="node22.html#paramtable">3</A>).
+
+<P>
+On the basis of the map positions and matches, FISH
+performs <I>detandemization</I>, in which
+multiple markers may be collapsed into single features. Two parameters control the
+detandemization process: MIN_SCORE and
+MAX_DIST.
+Markers with coordinates that are separated by MIN_DIST or less will be
+collapsed into a single feature if they are homologous to each other or to a
+third marker with a score at least as great as MIN_SCORE.
+
+<P>
+To calculate the relative order of features in the detandemized contig, each
+feature inherits the position of the marker having the lowest valued coordinate
+within the set of markers comprising the feature.
+The coordinates are then reassigned for features in all contigs from
+zero to one less than the number of features in the whole dataset.
+When transcriptional orientations are known, the feature inherits the majority
+orientation (either '1' or '-1') of the markers that comprise it.
+For example, if three out of the five markers that comprise a feature have a transcriptional
+orientation of '1', then the feature inherits that orientation. If there is no majority,
+then it is assigned a value of zero, for 'unknown'.
+
+<P>
+The score of a match between two features, when one or both of
+the features represents multiple markers, is taken, depending on the
+runtime parameter chosen, to be either the highest score or
+the average score for any of the pairs of component markers, one from each feature.
+
+<P>
+<HR>
+<!--Navigation Panel-->
+<A NAME="tex2html268"
+ HREF="node14.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html264"
+ HREF="node12.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html258"
+ HREF="node12.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html266"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html269"
+ HREF="node14.html">Step 2: From features</A>
+<B> Up:</B> <A NAME="tex2html265"
+ HREF="node12.html">How it works</A>
+<B> Previous:</B> <A NAME="tex2html259"
+ HREF="node12.html">How it works</A>
+   <B> <A NAME="tex2html267"
+ HREF="node1.html">Contents</A></B>
+<!--End of Navigation Panel-->
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node14.html b/docs/fishmanual/node14.html
new file mode 100644
index 0000000..9b1c800
--- /dev/null
+++ b/docs/fishmanual/node14.html
@@ -0,0 +1,100 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Step 2: From features to grid </TITLE>
+<META NAME="description" CONTENT="Step 2: From features to grid ">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="next" HREF="node19.html">
+<LINK REL="previous" HREF="node13.html">
+<LINK REL="up" HREF="node12.html">
+<LINK REL="next" HREF="node15.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html280"
+ HREF="node15.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html276"
+ HREF="node12.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html270"
+ HREF="node13.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html278"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html281"
+ HREF="node15.html">Removing low ranking matches</A>
+<B> Up:</B> <A NAME="tex2html277"
+ HREF="node12.html">How it works</A>
+<B> Previous:</B> <A NAME="tex2html271"
+ HREF="node13.html">Step 1: From markers</A>
+   <B> <A NAME="tex2html279"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H1><A NAME="SECTION00320000000000000000"></A><A NAME="step2"></A>
+<BR>
+Step 2: From features to grid
+</H1>
+In order to identify segmental homologies, FISH computes a grid for each pair of
+contigs. <I>Points</I> in the grid represent matches
+between pairs of features. The <IMG
+ WIDTH="11" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="img1.png"
+ ALT="$ i$"> and <IMG
+ WIDTH="14" HEIGHT="34" ALIGN="MIDDLE" BORDER="0"
+ SRC="img2.png"
+ ALT="$ j$"> coordinates of a point are taken to be the
+positions of the features within their respective contigs.
+Each position in the grid, whether or not a point is present, is called as a
+<I>cell</I>.
+
+<P>
+<BR><HR>
+<!--Table of Child-Links-->
+<A NAME="CHILD_LINKS"><STRONG>Subsections</STRONG></A>
+
+<UL>
+<LI><A NAME="tex2html282"
+ HREF="node15.html">Removing low ranking matches</A>
+<LI><A NAME="tex2html283"
+ HREF="node16.html">Numbering of points</A>
+<LI><A NAME="tex2html284"
+ HREF="node17.html">Enforcing symmetry</A>
+<LI><A NAME="tex2html285"
+ HREF="node18.html">Defining the neighborhood size</A>
+</UL>
+<!--End of Table of Child-Links-->
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node15.html b/docs/fishmanual/node15.html
new file mode 100644
index 0000000..0131c21
--- /dev/null
+++ b/docs/fishmanual/node15.html
@@ -0,0 +1,77 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Removing low ranking matches</TITLE>
+<META NAME="description" CONTENT="Removing low ranking matches">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="next" HREF="node16.html">
+<LINK REL="previous" HREF="node14.html">
+<LINK REL="up" HREF="node14.html">
+<LINK REL="next" HREF="node16.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html296"
+ HREF="node16.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html292"
+ HREF="node14.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html286"
+ HREF="node14.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html294"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html297"
+ HREF="node16.html">Numbering of points</A>
+<B> Up:</B> <A NAME="tex2html293"
+ HREF="node14.html">Step 2: From features</A>
+<B> Previous:</B> <A NAME="tex2html287"
+ HREF="node14.html">Step 2: From features</A>
+   <B> <A NAME="tex2html295"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H2><A NAME="SECTION00321000000000000000">
+Removing low ranking matches</A>
+</H2>
+The number of matches for each feature in the final grid can be
+limited by an adjustable parameter, TOP_HITS. If a match
+is not one of the highest TOP_HITS scoring matches for at least one of the features,
+then it is deleted. This step is necessary to removes some of the noise
+resulting from large gene families.
+
+<P>
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node16.html b/docs/fishmanual/node16.html
new file mode 100644
index 0000000..3b54f85
--- /dev/null
+++ b/docs/fishmanual/node16.html
@@ -0,0 +1,80 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Numbering of points</TITLE>
+<META NAME="description" CONTENT="Numbering of points">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="next" HREF="node17.html">
+<LINK REL="previous" HREF="node15.html">
+<LINK REL="up" HREF="node14.html">
+<LINK REL="next" HREF="node17.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html308"
+ HREF="node17.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html304"
+ HREF="node14.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html298"
+ HREF="node15.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html306"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html309"
+ HREF="node17.html">Enforcing symmetry</A>
+<B> Up:</B> <A NAME="tex2html305"
+ HREF="node14.html">Step 2: From features</A>
+<B> Previous:</B> <A NAME="tex2html299"
+ HREF="node15.html">Removing low ranking matches</A>
+   <B> <A NAME="tex2html307"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H2><A NAME="SECTION00322000000000000000">
+Numbering of points</A>
+</H2>
+Following this, each point in the grid is given a unique identifying number from zero to one
+less than the total
+number of points. These numbers are assigned to points in sorted hierarchical
+order, first by one coordinate and then by the other. Cells for
+which <IMG
+ WIDTH="45" HEIGHT="34" ALIGN="MIDDLE" BORDER="0"
+ SRC="img3.png"
+ ALT="$ i \geq j$"> are not included.
+
+<P>
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node17.html b/docs/fishmanual/node17.html
new file mode 100644
index 0000000..23acece
--- /dev/null
+++ b/docs/fishmanual/node17.html
@@ -0,0 +1,94 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Enforcing symmetry</TITLE>
+<META NAME="description" CONTENT="Enforcing symmetry">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="next" HREF="node18.html">
+<LINK REL="previous" HREF="node16.html">
+<LINK REL="up" HREF="node14.html">
+<LINK REL="next" HREF="node18.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html320"
+ HREF="node18.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html316"
+ HREF="node14.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html310"
+ HREF="node16.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html318"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html321"
+ HREF="node18.html">Defining the neighborhood size</A>
+<B> Up:</B> <A NAME="tex2html317"
+ HREF="node14.html">Step 2: From features</A>
+<B> Previous:</B> <A NAME="tex2html311"
+ HREF="node16.html">Numbering of points</A>
+   <B> <A NAME="tex2html319"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H2><A NAME="SECTION00323000000000000000">
+Enforcing symmetry</A>
+</H2>
+The above preprocessing steps have ensured that symmetry has been enforced in the grid, such
+that the match between features <IMG
+ WIDTH="11" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="img1.png"
+ ALT="$ i$"> and <IMG
+ WIDTH="14" HEIGHT="34" ALIGN="MIDDLE" BORDER="0"
+ SRC="img2.png"
+ ALT="$ j$"> has the same score as the match between features <IMG
+ WIDTH="14" HEIGHT="34" ALIGN="MIDDLE" BORDER="0"
+ SRC="img2.png"
+ ALT="$ j$"> and <IMG
+ WIDTH="11" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="img1.png"
+ ALT="$ i$">.
+Thus, we only need to consider the half of the grid containing <IMG
+ WIDTH="11" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="img1.png"
+ ALT="$ i$"> versus <IMG
+ WIDTH="14" HEIGHT="34" ALIGN="MIDDLE" BORDER="0"
+ SRC="img2.png"
+ ALT="$ j$"> in searching for
+blocks.
+
+<P>
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node18.html b/docs/fishmanual/node18.html
new file mode 100644
index 0000000..f1571a7
--- /dev/null
+++ b/docs/fishmanual/node18.html
@@ -0,0 +1,128 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Defining the neighborhood size</TITLE>
+<META NAME="description" CONTENT="Defining the neighborhood size">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="previous" HREF="node17.html">
+<LINK REL="up" HREF="node14.html">
+<LINK REL="next" HREF="node19.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html330"
+ HREF="node19.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html326"
+ HREF="node14.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html322"
+ HREF="node17.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html328"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html331"
+ HREF="node19.html">Step 3: From grid</A>
+<B> Up:</B> <A NAME="tex2html327"
+ HREF="node14.html">Step 2: From features</A>
+<B> Previous:</B> <A NAME="tex2html323"
+ HREF="node17.html">Enforcing symmetry</A>
+   <B> <A NAME="tex2html329"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H2><A NAME="SECTION00324000000000000000">
+Defining the neighborhood size</A>
+</H2>
+Blocks consist of sequences of points in which each point is within
+the neighborhood of the previous one.
+FISH calculates the size of the <I>neighborhood</I> for all points
+based on the total number of points <IMG
+ WIDTH="21" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="img4.png"
+ ALT="$ m$"> and cells <IMG
+ WIDTH="16" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="img5.png"
+ ALT="$ n$"> in the grid.
+The probability of a cell containing a point is <IMG
+ WIDTH="78" HEIGHT="37" ALIGN="MIDDLE" BORDER="0"
+ SRC="img6.png"
+ ALT="$ h=m/n$">.
+From this, and from an adjustable parameter <IMG
+ WIDTH="18" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="img7.png"
+ ALT="$ T$"> (see <A HREF="node23.html#alg_param">3.1</A>),
+FISH calculates the size of the neighborhood.
+In its current version, FISH measures distance between two points
+<!-- MATH
+ $(X_i, Y_i)$
+ -->
+<IMG
+ WIDTH="65" HEIGHT="37" ALIGN="MIDDLE" BORDER="0"
+ SRC="img8.png"
+ ALT="$ (X_i, Y_i)$"> and <!-- MATH
+ $(X_j, Y_j)$
+ -->
+<IMG
+ WIDTH="68" HEIGHT="37" ALIGN="MIDDLE" BORDER="0"
+ SRC="img9.png"
+ ALT="$ (X_j, Y_j)$"> using the Manhattan distance,
+<!-- MATH
+ $d = |X_i - X_j| + |Y_j - Y_i|$
+ -->
+<IMG
+ WIDTH="208" HEIGHT="37" ALIGN="MIDDLE" BORDER="0"
+ SRC="img10.png"
+ ALT="$ d = \vert X_i - X_j\vert + \vert Y_j - Y_i\vert$">.
+In order to be considered neighbors, two points must be closer than
+<P></P>
+<DIV ALIGN="CENTER"><A NAME="dT"></A><!-- MATH
+ \begin{equation}
+d_T = \frac{1}{2}+\sqrt{\frac{{\log}(1-T)}{{\log}(1-h)}}+\frac{1}{4}
+\end{equation}
+ -->
+<TABLE CELLPADDING="0" WIDTH="100%" ALIGN="CENTER">
+<TR VALIGN="MIDDLE">
+<TD NOWRAP ALIGN="CENTER"><IMG
+ WIDTH="230" HEIGHT="80" ALIGN="MIDDLE" BORDER="0"
+ SRC="img11.png"
+ ALT="$\displaystyle d_T = \frac{1}{2}+\sqrt{\frac{{\log}(1-T)}{{\log}(1-h)}}+\frac{1}{4}$"></TD>
+<TD NOWRAP WIDTH="10" ALIGN="RIGHT">
+(2.1)</TD></TR>
+</TABLE></DIV>
+<BR CLEAR="ALL"><P></P>
+
+<P>
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node19.html b/docs/fishmanual/node19.html
new file mode 100644
index 0000000..b62e891
--- /dev/null
+++ b/docs/fishmanual/node19.html
@@ -0,0 +1,87 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Step 3: From grid to blocks </TITLE>
+<META NAME="description" CONTENT="Step 3: From grid to blocks ">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="previous" HREF="node14.html">
+<LINK REL="up" HREF="node12.html">
+<LINK REL="next" HREF="node20.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html340"
+ HREF="node20.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html336"
+ HREF="node12.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html332"
+ HREF="node18.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html338"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html341"
+ HREF="node20.html">Choosing among multiple neighbors</A>
+<B> Up:</B> <A NAME="tex2html337"
+ HREF="node12.html">How it works</A>
+<B> Previous:</B> <A NAME="tex2html333"
+ HREF="node18.html">Defining the neighborhood size</A>
+   <B> <A NAME="tex2html339"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H1><A NAME="SECTION00330000000000000000"></A><A NAME="step3"></A>
+<BR>
+Step 3: From grid to blocks
+</H1>
+FISH uses a dynamic programming
+algorithm to identify all maximally extended blocks. For a detailed description of the
+algorithm, see [<A
+ HREF="node47.html#Calabrese2003">1</A>].
+
+<P>
+<BR><HR>
+<!--Table of Child-Links-->
+<A NAME="CHILD_LINKS"><STRONG>Subsections</STRONG></A>
+
+<UL>
+<LI><A NAME="tex2html342"
+ HREF="node20.html">Choosing among multiple neighbors</A>
+<LI><A NAME="tex2html343"
+ HREF="node21.html">Overlapping blocks</A>
+</UL>
+<!--End of Table of Child-Links-->
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node2.html b/docs/fishmanual/node2.html
new file mode 100644
index 0000000..2df6960
--- /dev/null
+++ b/docs/fishmanual/node2.html
@@ -0,0 +1,97 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Getting started</TITLE>
+<META NAME="description" CONTENT="Getting started">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="next" HREF="node12.html">
+<LINK REL="previous" HREF="node1.html">
+<LINK REL="up" HREF="fishmanual.html">
+<LINK REL="next" HREF="node3.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html118"
+ HREF="node3.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html114"
+ HREF="fishmanual.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html108"
+ HREF="node1.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html116"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html119"
+ HREF="node3.html">Introduction</A>
+<B> Up:</B> <A NAME="tex2html115"
+ HREF="fishmanual.html">User's Manual for FISH</A>
+<B> Previous:</B> <A NAME="tex2html109"
+ HREF="node1.html">Contents</A>
+   <B> <A NAME="tex2html117"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H1><A NAME="SECTION00200000000000000000">
+Getting started</A>
+</H1>
+ 6pt
+<BR><HR>
+<!--Table of Child-Links-->
+<A NAME="CHILD_LINKS"><STRONG>Subsections</STRONG></A>
+
+<UL>
+<LI><A NAME="tex2html120"
+ HREF="node3.html">Introduction</A>
+<LI><A NAME="tex2html121"
+ HREF="node4.html">Contact information</A>
+<LI><A NAME="tex2html122"
+ HREF="node5.html">Legal information</A>
+<LI><A NAME="tex2html123"
+ HREF="node6.html">Acknowledgements</A>
+<LI><A NAME="tex2html124"
+ HREF="node7.html">Availability</A>
+<UL>
+<LI><A NAME="tex2html125"
+ HREF="node8.html">Installing from source code</A>
+<LI><A NAME="tex2html126"
+ HREF="node9.html">Installing the Windows executable</A>
+<LI><A NAME="tex2html127"
+ HREF="node10.html">Installing the MacOSX executable</A>
+<LI><A NAME="tex2html128"
+ HREF="node11.html">Testing FISH on sample data</A>
+</UL></UL>
+<!--End of Table of Child-Links-->
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node20.html b/docs/fishmanual/node20.html
new file mode 100644
index 0000000..b5d5020
--- /dev/null
+++ b/docs/fishmanual/node20.html
@@ -0,0 +1,166 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Choosing among multiple neighbors</TITLE>
+<META NAME="description" CONTENT="Choosing among multiple neighbors">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="next" HREF="node21.html">
+<LINK REL="previous" HREF="node19.html">
+<LINK REL="up" HREF="node19.html">
+<LINK REL="next" HREF="node21.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html354"
+ HREF="node21.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html350"
+ HREF="node19.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html344"
+ HREF="node19.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html352"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html355"
+ HREF="node21.html">Overlapping blocks</A>
+<B> Up:</B> <A NAME="tex2html351"
+ HREF="node19.html">Step 3: From grid</A>
+<B> Previous:</B> <A NAME="tex2html345"
+ HREF="node19.html">Step 3: From grid</A>
+   <B> <A NAME="tex2html353"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H2><A NAME="SECTION00331000000000000000">
+Choosing among multiple neighbors</A>
+</H2>
+It can happen that a point may be in the neighborhood of more than one other point.
+In such a case, it is necessary to specify rules for which point will be chosen to extend the block.
+To do this, FISH ranks the cells within each neighborhood and chooses that neighbor
+having the highest rank, using an <I>ad hoc</I> formula that gives preference to points that
+preserve the colinear order of matching features along the two contigs.
+The rank <IMG
+ WIDTH="14" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="img12.png"
+ ALT="$ r$"> for each cell in the neighborhood of the candidate point is
+<P></P>
+<DIV ALIGN="CENTER"><!-- MATH
+ \begin{equation}
+r = w \frac{1/d_c}{\sum_{1}^{n}(1/d_c)}
+\end{equation}
+ -->
+<TABLE CELLPADDING="0" WIDTH="100%" ALIGN="CENTER">
+<TR VALIGN="MIDDLE">
+<TD NOWRAP ALIGN="CENTER"><IMG
+ WIDTH="135" HEIGHT="62" ALIGN="MIDDLE" BORDER="0"
+ SRC="img13.png"
+ ALT="$\displaystyle r = w \frac{1/d_c}{\sum_{1}^{n}(1/d_c)}$"></TD>
+<TD NOWRAP WIDTH="10" ALIGN="RIGHT">
+(2.2)</TD></TR>
+</TABLE></DIV>
+<BR CLEAR="ALL"><P></P>
+where <IMG
+ WIDTH="16" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="img5.png"
+ ALT="$ n$"> is the number of cells in the point's neighborhood, <IMG
+ WIDTH="21" HEIGHT="34" ALIGN="MIDDLE" BORDER="0"
+ SRC="img14.png"
+ ALT="$ d_c$"> is the
+distance
+of the cell from the point under consideration and <IMG
+ WIDTH="19" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="img15.png"
+ ALT="$ w$"> is the weight.
+The weight
+<P></P>
+<DIV ALIGN="CENTER"><!-- MATH
+ \begin{equation}
+w = \begin{cases}
+ 1 & \text{if the point is the first in the block},\\
+ 0.25 & \text{if an inversion is implied by the extension},\\
+ 0.75 & \text{otherwise}.
+ \end{cases}
+\end{equation}
+ -->
+<TABLE CELLPADDING="0" WIDTH="100%" ALIGN="CENTER">
+<TR VALIGN="MIDDLE">
+<TD NOWRAP ALIGN="CENTER"><IMG
+ WIDTH="440" HEIGHT="101" ALIGN="MIDDLE" BORDER="0"
+ SRC="img16.png"
+ ALT="$\displaystyle w = \begin{cases}1 & \text{if the point is the first in the block...
+... inversion is implied by the extension},\\ 0.75 & \text{otherwise}. \end{cases}$"></TD>
+<TD NOWRAP WIDTH="10" ALIGN="RIGHT">
+(2.3)</TD></TR>
+</TABLE></DIV>
+<BR CLEAR="ALL"><P></P>
+When multiple points have equal rank, the point is chosen that has the smallest value
+ of <!-- MATH
+ $|(|X_i - X_j|)-(|Y_j - Y_i|)|$
+ -->
+<IMG
+ WIDTH="213" HEIGHT="37" ALIGN="MIDDLE" BORDER="0"
+ SRC="img17.png"
+ ALT="$ \vert(\vert X_i - X_j\vert)-(\vert Y_j - Y_i\vert)\vert$">. This favors points close to the diagonal.
+
+<P>
+<HR>
+<!--Navigation Panel-->
+<A NAME="tex2html354"
+ HREF="node21.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html350"
+ HREF="node19.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html344"
+ HREF="node19.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html352"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html355"
+ HREF="node21.html">Overlapping blocks</A>
+<B> Up:</B> <A NAME="tex2html351"
+ HREF="node19.html">Step 3: From grid</A>
+<B> Previous:</B> <A NAME="tex2html345"
+ HREF="node19.html">Step 3: From grid</A>
+   <B> <A NAME="tex2html353"
+ HREF="node1.html">Contents</A></B>
+<!--End of Navigation Panel-->
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node21.html b/docs/fishmanual/node21.html
new file mode 100644
index 0000000..a35f835
--- /dev/null
+++ b/docs/fishmanual/node21.html
@@ -0,0 +1,75 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Overlapping blocks</TITLE>
+<META NAME="description" CONTENT="Overlapping blocks">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="previous" HREF="node20.html">
+<LINK REL="up" HREF="node19.html">
+<LINK REL="next" HREF="node22.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html364"
+ HREF="node22.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html360"
+ HREF="node19.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html356"
+ HREF="node20.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html362"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html365"
+ HREF="node22.html">Parameters</A>
+<B> Up:</B> <A NAME="tex2html361"
+ HREF="node19.html">Step 3: From grid</A>
+<B> Previous:</B> <A NAME="tex2html357"
+ HREF="node20.html">Choosing among multiple neighbors</A>
+   <B> <A NAME="tex2html363"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H2><A NAME="SECTION00332000000000000000">
+Overlapping blocks</A>
+</H2>
+FISH processes blocks in such a way as to ensure that only non-overlapping blocks
+are obtained. If a point could be included in multiple blocks, one of the blocks
+with highest score is chosen. The point is then made unavailable for inclusion in
+other blocks.
+
+<P>
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node22.html b/docs/fishmanual/node22.html
new file mode 100644
index 0000000..e465a49
--- /dev/null
+++ b/docs/fishmanual/node22.html
@@ -0,0 +1,201 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Parameters</TITLE>
+<META NAME="description" CONTENT="Parameters">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="next" HREF="node25.html">
+<LINK REL="previous" HREF="node12.html">
+<LINK REL="up" HREF="fishmanual.html">
+<LINK REL="next" HREF="node23.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html376"
+ HREF="node23.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html372"
+ HREF="fishmanual.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html366"
+ HREF="node21.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html374"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html377"
+ HREF="node23.html">Algorithmic parameters</A>
+<B> Up:</B> <A NAME="tex2html373"
+ HREF="fishmanual.html">User's Manual for FISH</A>
+<B> Previous:</B> <A NAME="tex2html367"
+ HREF="node21.html">Overlapping blocks</A>
+   <B> <A NAME="tex2html375"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H1><A NAME="SECTION00400000000000000000">
+Parameters</A>
+</H1>
+A number of parameters may be adjusted at the command-line when FISH is
+invoked. They may also be reviewed from the command line by invoking
+FISH with the help switch:
+<PRE>
+# fish -h
+</PRE>
+
+<P>
+The adjustable parameters are listed here and described in more detail below.
+<TABLE CELLPADDING=3 BORDER="1">
+<TR><TD ALIGN="LEFT"><A NAME="paramtable"></A>parameter</TD>
+<TD ALIGN="LEFT">switch</TD>
+<TD ALIGN="LEFT">default</TD>
+<TD ALIGN="LEFT">acceptable values</TD>
+</TR>
+<TR><TD ALIGN="LEFT">PRINT_BLOCKS</TD>
+<TD ALIGN="LEFT">-b</TD>
+<TD ALIGN="LEFT">off</TD>
+<TD ALIGN="LEFT">valid file name</TD>
+</TR>
+<TR><TD ALIGN="LEFT">PRINT_B_SIMPLE</TD>
+<TD ALIGN="LEFT">-B</TD>
+<TD ALIGN="LEFT">off</TD>
+<TD ALIGN="LEFT">valid file name</TD>
+</TR>
+<TR><TD ALIGN="LEFT">MIN_BLOCK_SIZE</TD>
+<TD ALIGN="LEFT">-m</TD>
+<TD ALIGN="LEFT">3</TD>
+<TD ALIGN="LEFT">integer greater than 1</TD>
+</TR>
+<TR><TD ALIGN="LEFT">PRINT_CONTIGS</TD>
+<TD ALIGN="LEFT">-C</TD>
+<TD ALIGN="LEFT">off</TD>
+<TD ALIGN="LEFT">valid filename</TD>
+</TR>
+<TR><TD ALIGN="LEFT">CONTROL_FILE</TD>
+<TD ALIGN="LEFT">-f</TD>
+<TD ALIGN="LEFT">control.txt</TD>
+<TD ALIGN="LEFT">valid filename</TD>
+</TR>
+<TR><TD ALIGN="LEFT">PRINT_GRIDS</TD>
+<TD ALIGN="LEFT">-g</TD>
+<TD ALIGN="LEFT">off</TD>
+<TD ALIGN="LEFT">valid filename</TD>
+</TR>
+<TR><TD ALIGN="LEFT">TOP_HITS</TD>
+<TD ALIGN="LEFT">-H</TD>
+<TD ALIGN="LEFT">5</TD>
+<TD ALIGN="LEFT">integer greater than 0</TD>
+</TR>
+<TR><TD ALIGN="LEFT">MAX_DIST</TD>
+<TD ALIGN="LEFT">-D</TD>
+<TD ALIGN="LEFT">10</TD>
+<TD ALIGN="LEFT">integer greater than 0</TD>
+</TR>
+<TR><TD ALIGN="LEFT">BLOCK_PROB</TD>
+<TD ALIGN="LEFT">-p</TD>
+<TD ALIGN="LEFT">0.001</TD>
+<TD ALIGN="LEFT">real between 0 and 1</TD>
+</TR>
+<TR><TD ALIGN="LEFT">QUIET_MODE</TD>
+<TD ALIGN="LEFT">-q</TD>
+<TD ALIGN="LEFT">off</TD>
+<TD ALIGN="LEFT">none</TD>
+</TR>
+<TR><TD ALIGN="LEFT">MIN_SCORE</TD>
+<TD ALIGN="LEFT">-S</TD>
+<TD ALIGN="LEFT">200</TD>
+<TD ALIGN="LEFT">real</TD>
+</TR>
+<TR><TD ALIGN="LEFT">TIMING</TD>
+<TD ALIGN="LEFT">-t</TD>
+<TD ALIGN="LEFT">off</TD>
+<TD ALIGN="LEFT">none</TD>
+</TR>
+<TR><TD ALIGN="LEFT">AVG_SCORE</TD>
+<TD ALIGN="LEFT">-A</TD>
+<TD ALIGN="LEFT">Max_Score</TD>
+<TD ALIGN="LEFT">none</TD>
+</TR>
+<TR><TD ALIGN="LEFT">T</TD>
+<TD ALIGN="LEFT">-T</TD>
+<TD ALIGN="LEFT">0.05</TD>
+<TD ALIGN="LEFT">real between 0 and 1</TD>
+</TR>
+<TR><TD ALIGN="LEFT">DETANDEMIZE</TD>
+<TD ALIGN="LEFT">-off</TD>
+<TD ALIGN="LEFT">on</TD>
+<TD ALIGN="LEFT">none</TD>
+</TR>
+</TABLE>
+
+<P>
+<BR><HR>
+<!--Table of Child-Links-->
+<A NAME="CHILD_LINKS"><STRONG>Subsections</STRONG></A>
+
+<UL>
+<LI><A NAME="tex2html378"
+ HREF="node23.html">Algorithmic parameters </A>
+<LI><A NAME="tex2html379"
+ HREF="node24.html">Input and output parameters </A>
+</UL>
+<!--End of Table of Child-Links-->
+<HR>
+<!--Navigation Panel-->
+<A NAME="tex2html376"
+ HREF="node23.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html372"
+ HREF="fishmanual.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html366"
+ HREF="node21.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html374"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html377"
+ HREF="node23.html">Algorithmic parameters</A>
+<B> Up:</B> <A NAME="tex2html373"
+ HREF="fishmanual.html">User's Manual for FISH</A>
+<B> Previous:</B> <A NAME="tex2html367"
+ HREF="node21.html">Overlapping blocks</A>
+   <B> <A NAME="tex2html375"
+ HREF="node1.html">Contents</A></B>
+<!--End of Navigation Panel-->
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node23.html b/docs/fishmanual/node23.html
new file mode 100644
index 0000000..df39872
--- /dev/null
+++ b/docs/fishmanual/node23.html
@@ -0,0 +1,144 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Algorithmic parameters </TITLE>
+<META NAME="description" CONTENT="Algorithmic parameters ">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
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+
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+
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+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html380"
+ HREF="node22.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html388"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html391"
+ HREF="node24.html">Input and output parameters</A>
+<B> Up:</B> <A NAME="tex2html387"
+ HREF="node22.html">Parameters</A>
+<B> Previous:</B> <A NAME="tex2html381"
+ HREF="node22.html">Parameters</A>
+   <B> <A NAME="tex2html389"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H1><A NAME="SECTION00410000000000000000"></A><A NAME="alg_param"></A>
+<BR>
+Algorithmic parameters
+</H1>
+A number of the adjustable parameters control the way in which FISH finds
+blocks. Altering these parameters can substantially influence the results.
+<DL>
+<DT><STRONG>MIN_BLOCK_SIZE</STRONG></DT>
+<DD>The minimum number of points needed to define a homologous block.
+</DD>
+<DT><STRONG>TOP_HITS</STRONG></DT>
+<DD>Matches that are not in among the TOP_HITS scoring matches for either
+component feature will be discarded.
+</DD>
+<DT><STRONG>MAX_DIST</STRONG></DT>
+<DD>The maximum number of intervening markers allowed between markers in t
+he same detandemized feature.
+</DD>
+<DT><STRONG>T</STRONG></DT>
+<DD>The probability of having one or more neighbors within a distance
+less than or equal to than <IMG
+ WIDTH="25" HEIGHT="34" ALIGN="MIDDLE" BORDER="0"
+ SRC="img18.png"
+ ALT="$ d_T$"> under the assumption that each cell contains
+a point with probability <IMG
+ WIDTH="16" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="img19.png"
+ ALT="$ h$">. Values of <IMG
+ WIDTH="18" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="img7.png"
+ ALT="$ T$"> closer to zero will result in blocks with more
+closely spaced points. This is roughly analogous to the gap parameter in local sequence alignment.
+</DD>
+<DT><STRONG>MIN_SCORE</STRONG></DT>
+<DD>Matches with scores less than MIN_SCORE will not
+be considered by FISH despite being listed in a match file.
+</DD>
+<DT><STRONG>AVG_SCORE</STRONG></DT>
+<DD>This option enforces symmetry between two matches
+(<I>e.g.</I> 1 versus 2 and 2 versus 1) by taking an
+average of the scores. If this averge is less than the MIN_SCORE, the
+match will be discarded.
+The default behavior is to choose the larger of the two scores.
+</DD>
+<DT><STRONG>DETANDEMIZE</STRONG></DT>
+<DD>This allows the user to turn detandemization off.
+</DD>
+</DL>
+
+<P>
+<HR>
+<!--Navigation Panel-->
+<A NAME="tex2html390"
+ HREF="node24.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html386"
+ HREF="node22.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html380"
+ HREF="node22.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
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+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html391"
+ HREF="node24.html">Input and output parameters</A>
+<B> Up:</B> <A NAME="tex2html387"
+ HREF="node22.html">Parameters</A>
+<B> Previous:</B> <A NAME="tex2html381"
+ HREF="node22.html">Parameters</A>
+   <B> <A NAME="tex2html389"
+ HREF="node1.html">Contents</A></B>
+<!--End of Navigation Panel-->
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node24.html b/docs/fishmanual/node24.html
new file mode 100644
index 0000000..21c56b6
--- /dev/null
+++ b/docs/fishmanual/node24.html
@@ -0,0 +1,149 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Input and output parameters </TITLE>
+<META NAME="description" CONTENT="Input and output parameters ">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
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+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
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+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
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+
+<LINK REL="previous" HREF="node23.html">
+<LINK REL="up" HREF="node22.html">
+<LINK REL="next" HREF="node25.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html400"
+ HREF="node25.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html396"
+ HREF="node22.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html392"
+ HREF="node23.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html398"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html401"
+ HREF="node25.html">File formats</A>
+<B> Up:</B> <A NAME="tex2html397"
+ HREF="node22.html">Parameters</A>
+<B> Previous:</B> <A NAME="tex2html393"
+ HREF="node23.html">Algorithmic parameters</A>
+   <B> <A NAME="tex2html399"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H1><A NAME="SECTION00420000000000000000"></A><A NAME="inoutparams"></A>
+<BR>
+Input and output parameters
+</H1>
+The remaining parameters control the input to and output from FISH.
+<DL>
+<DT><STRONG>QUIET_MODE</STRONG></DT>
+<DD>If selected, FISH will suppress the default screen
+output (see <A HREF="node31.html#screenoutput">4.2.1</A>). This switch takes no arguments.
+</DD>
+<DT><STRONG>TIMING</STRONG></DT>
+<DD>If selected, FISH will report the number of seconds
+elapsed between various execution time points. This switch takes no
+arguments.
+</DD>
+<DT><STRONG>CONTROL_FILE</STRONG></DT>
+<DD>Specifies the name of the file containing the instructions
+for FISH to read particular contig and match files <A HREF="node27.html#controlfile">4.1.1</A>.
+If not specified at the command-line, FISH will search for a file named
+``control.txt" and use that, if available.
+</DD>
+<DT><STRONG>PRINT_CONTIGS</STRONG></DT>
+<DD>Specifies the name of the file to which FISH
+writes contig output (see <A HREF="node35.html#contigfile">4.2.2</A>). Unless selected, no file will be written.
+</DD>
+<DT><STRONG>PRINT_GRIDS</STRONG></DT>
+<DD>Specifies the name of the file to which FISH writes
+grid output (see <A HREF="node36.html#gridfile">4.2.3</A>). Unless selected, no file will be written.
+</DD>
+<DT><STRONG>PRINT_BLOCKS</STRONG></DT>
+<DD>Specifies the name of the file to which FISH
+writes block output in human-friendly format (see <A HREF="node37.html#blockfile">4.2.4</A>).
+Unless selected, no file will be written.
+</DD>
+<DT><STRONG>PRINT_B_SIMPLE</STRONG></DT>
+<DD>Specifies the name of the file to which FISH
+writes an alternative format for the block output that is more computer friendly
+(see <A HREF="node37.html#blockfile">4.2.4</A>). Unless selected, no file will be written.
+</DD>
+<DT><STRONG>BLOCK_PROB</STRONG></DT>
+<DD>This specifies a value for the confidence level of a
+block. The confidence level is calculated as the expected number of blocks with
+<IMG
+ WIDTH="16" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="img5.png"
+ ALT="$ n$"> points divided by the observed number of blocks with <IMG
+ WIDTH="16" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="img5.png"
+ ALT="$ n$"> points. If the observed
+number does not sufficiently exceed the expected number (under the null model), then
+blocks of that size are flagged in the summary output. Some of these blocks may well be
+spurious.
+</DD>
+</DL>
+
+<P>
+<HR>
+<!--Navigation Panel-->
+<A NAME="tex2html400"
+ HREF="node25.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
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+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
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+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html401"
+ HREF="node25.html">File formats</A>
+<B> Up:</B> <A NAME="tex2html397"
+ HREF="node22.html">Parameters</A>
+<B> Previous:</B> <A NAME="tex2html393"
+ HREF="node23.html">Algorithmic parameters</A>
+   <B> <A NAME="tex2html399"
+ HREF="node1.html">Contents</A></B>
+<!--End of Navigation Panel-->
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node25.html b/docs/fishmanual/node25.html
new file mode 100644
index 0000000..a8ffafd
--- /dev/null
+++ b/docs/fishmanual/node25.html
@@ -0,0 +1,110 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>File formats </TITLE>
+<META NAME="description" CONTENT="File formats ">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
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+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
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+
+<LINK REL="next" HREF="node39.html">
+<LINK REL="previous" HREF="node22.html">
+<LINK REL="up" HREF="fishmanual.html">
+<LINK REL="next" HREF="node26.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html412"
+ HREF="node26.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html408"
+ HREF="fishmanual.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html402"
+ HREF="node24.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html410"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html413"
+ HREF="node26.html">Input files</A>
+<B> Up:</B> <A NAME="tex2html409"
+ HREF="fishmanual.html">User's Manual for FISH</A>
+<B> Previous:</B> <A NAME="tex2html403"
+ HREF="node24.html">Input and output parameters</A>
+   <B> <A NAME="tex2html411"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H1><A NAME="SECTION00500000000000000000"></A><A NAME="fileschapter"></A>
+<BR>
+File formats
+</H1>
+<BR><HR>
+<!--Table of Child-Links-->
+<A NAME="CHILD_LINKS"><STRONG>Subsections</STRONG></A>
+
+<UL>
+<LI><A NAME="tex2html414"
+ HREF="node26.html">Input files</A>
+<UL>
+<LI><A NAME="tex2html415"
+ HREF="node27.html">Control file </A>
+<LI><A NAME="tex2html416"
+ HREF="node28.html">Map files </A>
+<LI><A NAME="tex2html417"
+ HREF="node29.html">Match files </A>
+</UL>
+<BR>
+<LI><A NAME="tex2html418"
+ HREF="node30.html">Output</A>
+<UL>
+<LI><A NAME="tex2html419"
+ HREF="node31.html">Screen output </A>
+<UL>
+<LI><A NAME="tex2html420"
+ HREF="node32.html">Processing contigs</A>
+<LI><A NAME="tex2html421"
+ HREF="node33.html">Processing matches</A>
+<LI><A NAME="tex2html422"
+ HREF="node34.html">Processing blocks</A>
+</UL>
+<LI><A NAME="tex2html423"
+ HREF="node35.html">Contig file </A>
+<LI><A NAME="tex2html424"
+ HREF="node36.html">Grid file </A>
+<LI><A NAME="tex2html425"
+ HREF="node37.html">Block file </A>
+<LI><A NAME="tex2html426"
+ HREF="node38.html">Simple block file</A>
+</UL></UL>
+<!--End of Table of Child-Links-->
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node26.html b/docs/fishmanual/node26.html
new file mode 100644
index 0000000..43be707
--- /dev/null
+++ b/docs/fishmanual/node26.html
@@ -0,0 +1,88 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Input files</TITLE>
+<META NAME="description" CONTENT="Input files">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
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+
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+
+<LINK REL="next" HREF="node30.html">
+<LINK REL="previous" HREF="node25.html">
+<LINK REL="up" HREF="node25.html">
+<LINK REL="next" HREF="node27.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html437"
+ HREF="node27.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html433"
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+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html427"
+ HREF="node25.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html435"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html438"
+ HREF="node27.html">Control file</A>
+<B> Up:</B> <A NAME="tex2html434"
+ HREF="node25.html">File formats</A>
+<B> Previous:</B> <A NAME="tex2html428"
+ HREF="node25.html">File formats</A>
+   <B> <A NAME="tex2html436"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H1><A NAME="SECTION00510000000000000000">
+Input files</A>
+</H1>
+There are three types of input files: control files, map files and match files.
+The control file tells FISH the location of the map and the match
+files.
+
+<P>
+<BR><HR>
+<!--Table of Child-Links-->
+<A NAME="CHILD_LINKS"><STRONG>Subsections</STRONG></A>
+
+<UL>
+<LI><A NAME="tex2html439"
+ HREF="node27.html">Control file </A>
+<LI><A NAME="tex2html440"
+ HREF="node28.html">Map files </A>
+<LI><A NAME="tex2html441"
+ HREF="node29.html">Match files </A>
+</UL>
+<!--End of Table of Child-Links-->
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node27.html b/docs/fishmanual/node27.html
new file mode 100644
index 0000000..e58f9b8
--- /dev/null
+++ b/docs/fishmanual/node27.html
@@ -0,0 +1,130 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Control file </TITLE>
+<META NAME="description" CONTENT="Control file ">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
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+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
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+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
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+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html453"
+ HREF="node28.html">Map files</A>
+<B> Up:</B> <A NAME="tex2html449"
+ HREF="node26.html">Input files</A>
+<B> Previous:</B> <A NAME="tex2html443"
+ HREF="node26.html">Input files</A>
+   <B> <A NAME="tex2html451"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H2><A NAME="SECTION00511000000000000000"></A><A NAME="controlfile"></A>
+<BR>
+Control file
+</H2>
+A control file is used to specify the paths of the map and match files.
+The format of the control file can be seen in the sample provided.
+It is divided into two sections, one for map files and one for match files.
+
+<P>
+At a minimum, one map file and its associated match file are required.
+To compare two different contigs, map and match files are
+required for each. In addition, one or two match files must be specified
+that list the matches between features in contig 1 <I>vs.</I> 2, and/or 2
+<I>vs.</I> 1.
+
+<P>
+A list of the map files is preceded by the optional token '-maps' followed by a
+newline character, followed by a separate line for each contig that is to be
+analyzed. Each of those lines contains an integer, followed by whitespace,
+followed by a valid filename path, followed by a newline character. The integer
+is taken to be the name of a contig and the filename path tells FISH
+where to find the map file for that contig.
+
+<P>
+A list of the match files is preceded with the optional token '-matches'
+followed by a newline character, followed by a separate line for each pair of
+contigs to be analyzed. Each of those lines contains an integer, followed by
+whitespace, followed by an integer, followed by whitespace, followed by a valid
+filename path. The two integers specify the contigs for the match file.
+Note that there must be at least one comparison in which
+the integer of the first contig is less than the integer of the second contig.
+For example if 1 versus 2 does not exist, than 2 versus 1 is ignored. So if there is
+only one match file for a comparison between two contigs then that comparison must be
+written as 1 versus 2.
+
+<P>
+<HR>
+<!--Navigation Panel-->
+<A NAME="tex2html452"
+ HREF="node28.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
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+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
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+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
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+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html453"
+ HREF="node28.html">Map files</A>
+<B> Up:</B> <A NAME="tex2html449"
+ HREF="node26.html">Input files</A>
+<B> Previous:</B> <A NAME="tex2html443"
+ HREF="node26.html">Input files</A>
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+ HREF="node1.html">Contents</A></B>
+<!--End of Navigation Panel-->
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node28.html b/docs/fishmanual/node28.html
new file mode 100644
index 0000000..6872fa9
--- /dev/null
+++ b/docs/fishmanual/node28.html
@@ -0,0 +1,85 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Map files </TITLE>
+<META NAME="description" CONTENT="Map files ">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
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+
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+
+<LINK REL="next" HREF="node29.html">
+<LINK REL="previous" HREF="node27.html">
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+</HEAD>
+
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+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html460"
+ HREF="node26.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html454"
+ HREF="node27.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html462"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html465"
+ HREF="node29.html">Match files</A>
+<B> Up:</B> <A NAME="tex2html461"
+ HREF="node26.html">Input files</A>
+<B> Previous:</B> <A NAME="tex2html455"
+ HREF="node27.html">Control file</A>
+   <B> <A NAME="tex2html463"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H2><A NAME="SECTION00512000000000000000"></A><A NAME="mapfile"></A>
+<BR>
+Map files
+</H2>
+Each map file lists the names and transcriptional orientation (if known) of all
+the markers on one contig. For an example, see Section <A HREF="node39.html#examplefiles">5</A>.
+Markers must be listed in positional order. Each line contains a
+unique marker name,
+followed by a tab character, followed by the transcriptional orientation.
+Marker names can be character string up to a maximum length of 100 that does not include
+whitespace or the '&' character. (This value can be modified
+in the file ``fish.cpp" by changing the value of MAXBUFFER and recompiling).
+Marker orientation is taken
+relative to the contig as a whole. Thus, if marker 1 is coded on the same
+strand as marker 2, then both markers should be assigned the same direction. Orientation
+can take values '-1', '0' and '1'. Zero is used for markers of unknown orientation.
+
+<P>
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node29.html b/docs/fishmanual/node29.html
new file mode 100644
index 0000000..7af1bf7
--- /dev/null
+++ b/docs/fishmanual/node29.html
@@ -0,0 +1,85 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Match files </TITLE>
+<META NAME="description" CONTENT="Match files ">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
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+
+<LINK REL="previous" HREF="node28.html">
+<LINK REL="up" HREF="node26.html">
+<LINK REL="next" HREF="node30.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html474"
+ HREF="node30.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html470"
+ HREF="node26.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html466"
+ HREF="node28.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html472"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html475"
+ HREF="node30.html">Output</A>
+<B> Up:</B> <A NAME="tex2html471"
+ HREF="node26.html">Input files</A>
+<B> Previous:</B> <A NAME="tex2html467"
+ HREF="node28.html">Map files</A>
+   <B> <A NAME="tex2html473"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H2><A NAME="SECTION00513000000000000000"></A><A NAME="matchfile"></A>
+<BR>
+Match files
+</H2>
+Each match file lists all the homologies between markers in a pair of contigs. For an
+example, see Section <A HREF="node39.html#examplefiles">5</A>.
+There are three columns in the matchfile. The first two columns may be strings,
+but the
+third column needs to be an integer. The first and second columns contain the
+gene names
+from the first and second contig respectively.
+The integer in the third column must be some measure of the strength of the match between
+the two markers. FISH
+assumes that the larger the integer, the stronger the match. If information is
+not available on the strengths of the matches between genes, one can, for
+example, assign all scores to be zero, and set MIN_SCORE to be zero at runtime.
+All self matches are discarded.
+
+<P>
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node3.html b/docs/fishmanual/node3.html
new file mode 100644
index 0000000..5262976
--- /dev/null
+++ b/docs/fishmanual/node3.html
@@ -0,0 +1,129 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Introduction</TITLE>
+<META NAME="description" CONTENT="Introduction">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
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+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="next" HREF="node4.html">
+<LINK REL="previous" HREF="node2.html">
+<LINK REL="up" HREF="node2.html">
+<LINK REL="next" HREF="node4.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html139"
+ HREF="node4.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html135"
+ HREF="node2.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html129"
+ HREF="node2.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html137"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html140"
+ HREF="node4.html">Contact information</A>
+<B> Up:</B> <A NAME="tex2html136"
+ HREF="node2.html">Getting started</A>
+<B> Previous:</B> <A NAME="tex2html130"
+ HREF="node2.html">Getting started</A>
+   <B> <A NAME="tex2html138"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H1><A NAME="SECTION00210000000000000000">
+Introduction</A>
+</H1>
+Genomic regions that have descended from a common ancestral region are said to
+be <I>segmental homologs</I>. FISH is software for the fast
+identification and statistical evaluation of segmental homologs.
+
+<P>
+The software treats each input genome as a string of <I>features</I>.
+A feature may correspond to one marker, or sometimes to multiple homologous
+markers that
+are very close to one another on a contig.
+Each string of features (whether it is a compete chromosome or some smaller
+physical or genetic linkage group) is referred to as a <I>contig</I>.
+<I>Matches</I> are pairwise homologies among markers, which, along with the
+position of markers on contigs, constitute the primary input data.
+FISH finds <I>blocks</I> of putative segmental homology by
+identifying paired regions in which multiple matches
+occur and where the underlying features are in roughly colinear order.
+As described more fully below, FISH
+evaluates the probability of observing each block under a null model
+in
+which matches are distributed uniformly at random among features.
+
+<P>
+Users of FISH should cite the following paper (in which more detail regarding the method
+can be found):
+
+<UL>
+<LI>Calabrese PP, Chakravarty S, Vision TJ (2003) Fast identification and
+statistical evaluation of segmental homologies in comparative maps. <I>Bioinformatics</I> 19, i74-i80.
+</LI>
+</UL>
+
+<P>
+<HR>
+<!--Navigation Panel-->
+<A NAME="tex2html139"
+ HREF="node4.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
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+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
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+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
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+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html140"
+ HREF="node4.html">Contact information</A>
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+ HREF="node2.html">Getting started</A>
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+ HREF="node2.html">Getting started</A>
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+ HREF="node1.html">Contents</A></B>
+<!--End of Navigation Panel-->
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node30.html b/docs/fishmanual/node30.html
new file mode 100644
index 0000000..4119c03
--- /dev/null
+++ b/docs/fishmanual/node30.html
@@ -0,0 +1,101 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Output</TITLE>
+<META NAME="description" CONTENT="Output">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
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+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="previous" HREF="node26.html">
+<LINK REL="up" HREF="node25.html">
+<LINK REL="next" HREF="node31.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html484"
+ HREF="node31.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html480"
+ HREF="node25.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html476"
+ HREF="node29.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
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+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html485"
+ HREF="node31.html">Screen output</A>
+<B> Up:</B> <A NAME="tex2html481"
+ HREF="node25.html">File formats</A>
+<B> Previous:</B> <A NAME="tex2html477"
+ HREF="node29.html">Match files</A>
+   <B> <A NAME="tex2html483"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H1><A NAME="SECTION00520000000000000000">
+Output</A>
+</H1>
+FISH can generate a variety of different output streams depending on the user's
+selections. FISH can also report the time spent at various stages in
+the analysis. This
+option can be selected by using the -t switch (see Section <A HREF="node22.html#paramtable">3</A>).
+
+<P>
+<BR><HR>
+<!--Table of Child-Links-->
+<A NAME="CHILD_LINKS"><STRONG>Subsections</STRONG></A>
+
+<UL>
+<LI><A NAME="tex2html486"
+ HREF="node31.html">Screen output </A>
+<UL>
+<LI><A NAME="tex2html487"
+ HREF="node32.html">Processing contigs</A>
+<LI><A NAME="tex2html488"
+ HREF="node33.html">Processing matches</A>
+<LI><A NAME="tex2html489"
+ HREF="node34.html">Processing blocks</A>
+</UL>
+<BR>
+<LI><A NAME="tex2html490"
+ HREF="node35.html">Contig file </A>
+<LI><A NAME="tex2html491"
+ HREF="node36.html">Grid file </A>
+<LI><A NAME="tex2html492"
+ HREF="node37.html">Block file </A>
+<LI><A NAME="tex2html493"
+ HREF="node38.html">Simple block file</A>
+</UL>
+<!--End of Table of Child-Links-->
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node31.html b/docs/fishmanual/node31.html
new file mode 100644
index 0000000..283bf56
--- /dev/null
+++ b/docs/fishmanual/node31.html
@@ -0,0 +1,102 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Screen output </TITLE>
+<META NAME="description" CONTENT="Screen output ">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="next" HREF="node35.html">
+<LINK REL="previous" HREF="node30.html">
+<LINK REL="up" HREF="node30.html">
+<LINK REL="next" HREF="node32.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html504"
+ HREF="node32.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html500"
+ HREF="node30.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html494"
+ HREF="node30.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html502"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html505"
+ HREF="node32.html">Processing contigs</A>
+<B> Up:</B> <A NAME="tex2html501"
+ HREF="node30.html">Output</A>
+<B> Previous:</B> <A NAME="tex2html495"
+ HREF="node30.html">Output</A>
+   <B> <A NAME="tex2html503"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H2><A NAME="SECTION00521000000000000000"></A><A NAME="screenoutput"></A>
+<BR>
+Screen output
+</H2>
+Unless the QUIET_MODE has been selected, FISH will report results from
+each stage of the analysis to standard output (STDOUT). See Section
+<A HREF="node39.html#examplefiles">5</A> for an excerpt from the sample file ``fish_out.txt".
+The STDOUT stream may be directed to a file, rather than to the terminal, by using the
+<IMG
+ WIDTH="19" HEIGHT="34" ALIGN="MIDDLE" BORDER="0"
+ SRC="img20.png"
+ ALT="$ >$"> redirection operator, like so
+<PRE>
+# fish [options]> myfile.txt
+</PRE>
+
+<P>
+At the beginning of the process, FISH sends STDOUT a brief title
+message, including the current version number, the date and time at which the
+process was initiated, and the control file name.
+
+<P>
+<BR><HR>
+<!--Table of Child-Links-->
+<A NAME="CHILD_LINKS"><STRONG>Subsections</STRONG></A>
+
+<UL>
+<LI><A NAME="tex2html506"
+ HREF="node32.html">Processing contigs</A>
+<LI><A NAME="tex2html507"
+ HREF="node33.html">Processing matches</A>
+<LI><A NAME="tex2html508"
+ HREF="node34.html">Processing blocks</A>
+</UL>
+<!--End of Table of Child-Links-->
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node32.html b/docs/fishmanual/node32.html
new file mode 100644
index 0000000..56dcbab
--- /dev/null
+++ b/docs/fishmanual/node32.html
@@ -0,0 +1,77 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Processing contigs</TITLE>
+<META NAME="description" CONTENT="Processing contigs">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="next" HREF="node33.html">
+<LINK REL="previous" HREF="node31.html">
+<LINK REL="up" HREF="node31.html">
+<LINK REL="next" HREF="node33.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html519"
+ HREF="node33.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html515"
+ HREF="node31.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html509"
+ HREF="node31.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html517"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html520"
+ HREF="node33.html">Processing matches</A>
+<B> Up:</B> <A NAME="tex2html516"
+ HREF="node31.html">Screen output</A>
+<B> Previous:</B> <A NAME="tex2html510"
+ HREF="node31.html">Screen output</A>
+   <B> <A NAME="tex2html518"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H3><A NAME="SECTION00521100000000000000">
+Processing contigs</A>
+</H3>
+FISH displays the values of the two relevant parameters for the contig
+processing stage analysis: MIN_SCORE and MAX_DIST. Once detandemization is
+complete, a table is written that displays the number of markers and features
+within each contig. Detailed information on which markers compose which features
+ is written to a file if the PRINT_CONTIGS parameter has been selected.
+
+<P>
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node33.html b/docs/fishmanual/node33.html
new file mode 100644
index 0000000..6097eeb
--- /dev/null
+++ b/docs/fishmanual/node33.html
@@ -0,0 +1,79 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Processing matches</TITLE>
+<META NAME="description" CONTENT="Processing matches">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="next" HREF="node34.html">
+<LINK REL="previous" HREF="node32.html">
+<LINK REL="up" HREF="node31.html">
+<LINK REL="next" HREF="node34.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html531"
+ HREF="node34.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html527"
+ HREF="node31.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html521"
+ HREF="node32.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html529"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html532"
+ HREF="node34.html">Processing blocks</A>
+<B> Up:</B> <A NAME="tex2html528"
+ HREF="node31.html">Screen output</A>
+<B> Previous:</B> <A NAME="tex2html522"
+ HREF="node32.html">Processing contigs</A>
+   <B> <A NAME="tex2html530"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H3><A NAME="SECTION00521200000000000000">
+Processing matches</A>
+</H3>
+FISH displays the values of the relevant parameters of the match
+processing stage, MIN_SCORE and TOP_HITS. Note that the current and previous
+value for for MIN_SCORE must always agree. Once the calculations are
+complete, FISH displays the number of points and the number
+of cells for each pair of contigs in the analysis. In addition, the coordinates of
+the points in the detandemized dataset are written
+to a file if PRINT_GRIDS has been selected.
+
+<P>
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node34.html b/docs/fishmanual/node34.html
new file mode 100644
index 0000000..f9b2063
--- /dev/null
+++ b/docs/fishmanual/node34.html
@@ -0,0 +1,166 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Processing blocks</TITLE>
+<META NAME="description" CONTENT="Processing blocks">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="previous" HREF="node33.html">
+<LINK REL="up" HREF="node31.html">
+<LINK REL="next" HREF="node35.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html541"
+ HREF="node35.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html537"
+ HREF="node31.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html533"
+ HREF="node33.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html539"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html542"
+ HREF="node35.html">Contig file</A>
+<B> Up:</B> <A NAME="tex2html538"
+ HREF="node31.html">Screen output</A>
+<B> Previous:</B> <A NAME="tex2html534"
+ HREF="node33.html">Processing matches</A>
+   <B> <A NAME="tex2html540"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H3><A NAME="SECTION00521300000000000000">
+Processing blocks</A>
+</H3>
+FISH first displays the key adjustable parameter of the block finding
+stage, <IMG
+ WIDTH="18" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="img7.png"
+ ALT="$ T$">. Following this is a series of numbers which depend on both the
+dataset and the adjustable parameters:
+
+<UL>
+<LI><IMG
+ WIDTH="22" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="img21.png"
+ ALT="$ N$">, the total number of points in the grid
+</LI>
+<LI><IMG
+ WIDTH="20" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="img22.png"
+ ALT="$ F$">, the total number of features in the dataset
+</LI>
+<LI>the total number of cells in the grid, calculated as <IMG
+ WIDTH="100" HEIGHT="37" ALIGN="MIDDLE" BORDER="0"
+ SRC="img23.png"
+ ALT="$ F(F-1)/2$">
+</LI>
+<LI><IMG
+ WIDTH="16" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="img19.png"
+ ALT="$ h$">, the proportion of cells in the grid that contain a point
+</LI>
+<LI><IMG
+ WIDTH="25" HEIGHT="34" ALIGN="MIDDLE" BORDER="0"
+ SRC="img18.png"
+ ALT="$ d_T$">, the neighborhood size within which there is only a <IMG
+ WIDTH="18" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="img7.png"
+ ALT="$ T$"> probability of
+encountering another point if points in the grid are distributed uniformly at
+random (see Equation <A HREF="node18.html#dT">2.1</A>)
+</LI>
+<LI>MIN_BLOCK_SIZE, the number of points in the smallest block to be reported.
+</LI>
+</UL>
+Once the blocks have been identified, FISH will also display the total
+number of blocks.
+
+<P>
+The length distribution of the blocks is displayed as a vertical histogram. To
+the right of each bar is listed the number of blocks of length <IMG
+ WIDTH="17" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="img24.png"
+ ALT="$ L$">, as measured
+by the number of points. If the number of blocks is greater than 50, the true amount is not
+represented by '*' characters and the block frequency is preceded by '...'.
+To the left of the histogram is shown the corresponding <IMG
+ WIDTH="14" HEIGHT="34" ALIGN="MIDDLE" BORDER="0"
+ SRC="img25.png"
+ ALT="$ p$">-value for observing
+a block of length <IMG
+ WIDTH="17" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="img24.png"
+ ALT="$ L$"> (see Section <A HREF="node37.html#blockfile">4.2.4</A>), and the expected number, under the null model.
+If the proportion of expected to observed blocks of length <IMG
+ WIDTH="17" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="img24.png"
+ ALT="$ L$"> is greater than
+BLOCK_PROB, then the frequency of observed blocks is followed by an exclamation
+mark. This indicates that blocks of this length have not been observed sufficiently
+more frequently than expected, and so the individual blocks may not be biologically
+meaningful.
+
+<P>
+<HR>
+<!--Navigation Panel-->
+<A NAME="tex2html541"
+ HREF="node35.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html537"
+ HREF="node31.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html533"
+ HREF="node33.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html539"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html542"
+ HREF="node35.html">Contig file</A>
+<B> Up:</B> <A NAME="tex2html538"
+ HREF="node31.html">Screen output</A>
+<B> Previous:</B> <A NAME="tex2html534"
+ HREF="node33.html">Processing matches</A>
+   <B> <A NAME="tex2html540"
+ HREF="node1.html">Contents</A></B>
+<!--End of Navigation Panel-->
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node35.html b/docs/fishmanual/node35.html
new file mode 100644
index 0000000..1728034
--- /dev/null
+++ b/docs/fishmanual/node35.html
@@ -0,0 +1,85 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Contig file </TITLE>
+<META NAME="description" CONTENT="Contig file ">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="next" HREF="node36.html">
+<LINK REL="previous" HREF="node31.html">
+<LINK REL="up" HREF="node30.html">
+<LINK REL="next" HREF="node36.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html553"
+ HREF="node36.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html549"
+ HREF="node30.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html543"
+ HREF="node34.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html551"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html554"
+ HREF="node36.html">Grid file</A>
+<B> Up:</B> <A NAME="tex2html550"
+ HREF="node30.html">Output</A>
+<B> Previous:</B> <A NAME="tex2html544"
+ HREF="node34.html">Processing blocks</A>
+   <B> <A NAME="tex2html552"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H2><A NAME="SECTION00522000000000000000"></A><A NAME="contigfile"></A>
+<BR>
+Contig file
+</H2>
+If the PRINT_CONTIGS option is selected, FISH will output a contig
+file with the specified name. See Section <A HREF="node39.html#examplefiles">5</A> for an example. The
+contig file allows translation between feature numbers and marker names.
+
+<P>
+The top of the contig file displays the time at which the process was initiated.
+This is followed by the parameter list, which includes the name of the control
+file and the values of MIN_SCORE and MAX_DIST. This is followed by a
+table showing the number of markers and features in each contig. Finally, a
+table is presented in which, for each feature, the contig, the composite
+direction and the names of the markers (from the map file) associated with that
+feature are shown.
+
+<P>
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node36.html b/docs/fishmanual/node36.html
new file mode 100644
index 0000000..5492e76
--- /dev/null
+++ b/docs/fishmanual/node36.html
@@ -0,0 +1,86 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Grid file </TITLE>
+<META NAME="description" CONTENT="Grid file ">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="next" HREF="node37.html">
+<LINK REL="previous" HREF="node35.html">
+<LINK REL="up" HREF="node30.html">
+<LINK REL="next" HREF="node37.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html565"
+ HREF="node37.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html561"
+ HREF="node30.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html555"
+ HREF="node35.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html563"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html566"
+ HREF="node37.html">Block file</A>
+<B> Up:</B> <A NAME="tex2html562"
+ HREF="node30.html">Output</A>
+<B> Previous:</B> <A NAME="tex2html556"
+ HREF="node35.html">Contig file</A>
+   <B> <A NAME="tex2html564"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H2><A NAME="SECTION00523000000000000000"></A><A NAME="gridfile"></A>
+<BR>
+Grid file
+</H2>
+If the PRINT_GRIDS option is selected, FISH will output a grid file
+with the specified name. See Section <A HREF="node39.html#examplefiles">5</A> for an example. The grid file
+allows translation between points and features as well a summary of the
+parameters and results for the match processing step.
+
+<P>
+The top of the grid file displays the time at which the process was initiated.
+This is followed by the parameter list, which includes the name of the control
+file and the values of MIN_SCORE and TOP_HITS. This is followed by a
+table showing the number of points and cells for each pair of contigs. Finally,
+the points are listed. For each point, the associated contigs, the
+associated features, and the composite score are shown. See Section <A HREF="node37.html#blockfile">4.2.4</A>
+for an explanation of how the score is derived.
+
+<P>
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node37.html b/docs/fishmanual/node37.html
new file mode 100644
index 0000000..f09dcdc
--- /dev/null
+++ b/docs/fishmanual/node37.html
@@ -0,0 +1,181 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Block file </TITLE>
+<META NAME="description" CONTENT="Block file ">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="next" HREF="node38.html">
+<LINK REL="previous" HREF="node36.html">
+<LINK REL="up" HREF="node30.html">
+<LINK REL="next" HREF="node38.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html577"
+ HREF="node38.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html573"
+ HREF="node30.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html567"
+ HREF="node36.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html575"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html578"
+ HREF="node38.html">Simple block file</A>
+<B> Up:</B> <A NAME="tex2html574"
+ HREF="node30.html">Output</A>
+<B> Previous:</B> <A NAME="tex2html568"
+ HREF="node36.html">Grid file</A>
+   <B> <A NAME="tex2html576"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H2><A NAME="SECTION00524000000000000000"></A><A NAME="blockfile"></A>
+<BR>
+Block file
+</H2>
+If the PRINT_BLOCKS option is selected, FISH will output a block file
+with the specified name. See Section <A HREF="node39.html#examplefiles">5</A> for an example.
+
+<P>
+The top of the block file displays the time at which the process was initiated
+and the control file used. This is followed by the parameter list. This list,
+similar to the one output to STDOUT (see <A HREF="node31.html#screenoutput">4.2.1</A>) includes the name
+of the control file, the value of the threshold paremeter <IMG
+ WIDTH="18" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="img7.png"
+ ALT="$ T$">, the total number
+of points in the grid, the total number of features in the dataset,
+the total number of cells in the grid,
+the proportion of cells that contain a point <IMG
+ WIDTH="16" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="img19.png"
+ ALT="$ h$">, the size of the
+neighborhood <IMG
+ WIDTH="25" HEIGHT="34" ALIGN="MIDDLE" BORDER="0"
+ SRC="img18.png"
+ ALT="$ d_T$">, the minimum block size to be reported, and the total number of
+blocks found in the dataset.
+
+<P>
+This is followed by individual tables for each block. Within each, there is an
+upper panel that lists the number of points and the associated contigs. And there is
+a lower panel that lists each point in the block in sequence. For each, the table
+shows the number of the point,
+the distance from the previous point, the names of the markers for the associated
+features (in the format markers for feature 1 markers for feature 2), and the product
+of the orientation of the point with the previous point in the block. This product may take a
+value of -1, 0 or 1. If values
+switch frequently between -1 and 1, then transcriptional orientation is not well-conserved
+within that block, and the user may wish to regard this block with suspicion.
+Zero indicates 'unknown'.
+
+<P>
+At the bottom of the blocks file, the number of blocks seen between each pair of contigs is reported.
+Below that, the length distribution of blocks is reported. For blocks with a given number of points,
+the observed and expected numbers of blocks are shown followed by the <IMG
+ WIDTH="14" HEIGHT="34" ALIGN="MIDDLE" BORDER="0"
+ SRC="img25.png"
+ ALT="$ p$">-value for blocks of that
+length. The <IMG
+ WIDTH="14" HEIGHT="34" ALIGN="MIDDLE" BORDER="0"
+ SRC="img25.png"
+ ALT="$ p$">-value is calculated as described in ([<A
+ HREF="node47.html#Calabrese2003">1</A>])
+<P></P>
+<DIV ALIGN="CENTER"><!-- MATH
+ \begin{equation}
+p = 1-e^{-rc p_u}
+\end{equation}
+ -->
+<TABLE CELLPADDING="0" WIDTH="100%" ALIGN="CENTER">
+<TR VALIGN="MIDDLE">
+<TD NOWRAP ALIGN="CENTER"><IMG
+ WIDTH="119" HEIGHT="39" ALIGN="MIDDLE" BORDER="0"
+ SRC="img26.png"
+ ALT="$\displaystyle p = 1-e^{-rc p_u}$"></TD>
+<TD NOWRAP WIDTH="10" ALIGN="RIGHT">
+(4.1)</TD></TR>
+</TABLE></DIV>
+<BR CLEAR="ALL"><P></P>
+where <IMG
+ WIDTH="22" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="img27.png"
+ ALT="$ rc$"> is the total number of cells in the grid, <!-- MATH
+ $p_u = h(nh)^{k-1}$
+ -->
+<IMG
+ WIDTH="121" HEIGHT="40" ALIGN="MIDDLE" BORDER="0"
+ SRC="img28.png"
+ ALT="$ p_u = h(nh)^{k-1}$">, and <IMG
+ WIDTH="16" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="img5.png"
+ ALT="$ n$">
+is the number of cells in a neighborhood of size <IMG
+ WIDTH="25" HEIGHT="34" ALIGN="MIDDLE" BORDER="0"
+ SRC="img18.png"
+ ALT="$ d_T$">.
+
+<P>
+<HR>
+<!--Navigation Panel-->
+<A NAME="tex2html577"
+ HREF="node38.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html573"
+ HREF="node30.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html567"
+ HREF="node36.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html575"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html578"
+ HREF="node38.html">Simple block file</A>
+<B> Up:</B> <A NAME="tex2html574"
+ HREF="node30.html">Output</A>
+<B> Previous:</B> <A NAME="tex2html568"
+ HREF="node36.html">Grid file</A>
+   <B> <A NAME="tex2html576"
+ HREF="node1.html">Contents</A></B>
+<!--End of Navigation Panel-->
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node38.html b/docs/fishmanual/node38.html
new file mode 100644
index 0000000..e26598f
--- /dev/null
+++ b/docs/fishmanual/node38.html
@@ -0,0 +1,77 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Simple block file</TITLE>
+<META NAME="description" CONTENT="Simple block file">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="previous" HREF="node37.html">
+<LINK REL="up" HREF="node30.html">
+<LINK REL="next" HREF="node39.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html587"
+ HREF="node39.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html583"
+ HREF="node30.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html579"
+ HREF="node37.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html585"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html588"
+ HREF="node39.html">An example</A>
+<B> Up:</B> <A NAME="tex2html584"
+ HREF="node30.html">Output</A>
+<B> Previous:</B> <A NAME="tex2html580"
+ HREF="node37.html">Block file</A>
+   <B> <A NAME="tex2html586"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H2><A NAME="SECTION00525000000000000000">
+Simple block file</A>
+</H2>
+FISH provides the option of printing a more computer readable
+block file by choosing the PRINT_B_SIMPLE option. The first two lines report the number of
+blocks and the total number of points in all blocks, respectively. Each subsequent line
+reports the output for one block. The first number in each line is the number of points in that
+block. This is followed by comma-delimited list of the points themselves. Each block is terminated
+with an asterisk.
+
+<P>
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node39.html b/docs/fishmanual/node39.html
new file mode 100644
index 0000000..a483dec
--- /dev/null
+++ b/docs/fishmanual/node39.html
@@ -0,0 +1,113 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>An example </TITLE>
+<META NAME="description" CONTENT="An example ">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="next" HREF="node47.html">
+<LINK REL="previous" HREF="node25.html">
+<LINK REL="up" HREF="fishmanual.html">
+<LINK REL="next" HREF="node40.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html599"
+ HREF="node40.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html595"
+ HREF="fishmanual.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html589"
+ HREF="node38.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html597"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html600"
+ HREF="node40.html">A control input file</A>
+<B> Up:</B> <A NAME="tex2html596"
+ HREF="fishmanual.html">User's Manual for FISH</A>
+<B> Previous:</B> <A NAME="tex2html590"
+ HREF="node38.html">Simple block file</A>
+   <B> <A NAME="tex2html598"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H1><A NAME="SECTION00600000000000000000"></A><A NAME="examplefiles"></A>
+<BR>
+An example
+</H1>
+The following truncated input and output files come from a re-analysis of the
+segmental homology within and among the five chromosomes
+of <I>Arabidopsis thaliana</I> [<A
+ HREF="node47.html#Calabrese2003">1</A>,<A
+ HREF="node47.html#Vision2000">2</A>]
+All the genes that received AtXgXXXXX codes in the TIGR version 3.0 release
+of the genome annotation have been included in this dataset.
+Assuming that one is in the same directory as the example
+input files, one can reproduce this session by invoking FISH with the
+following options:
+<PRE>
+# fish -b blocks.txt
+ -g grids.txt
+ -C contigs.txt
+ -B simpleblocks.txt
+ -t > fish_out.txt
+</PRE>
+An explanation of the content of these files is provided in chapter
+<A HREF="node25.html#fileschapter">4</A>.
+
+<P>
+<BR><HR>
+<!--Table of Child-Links-->
+<A NAME="CHILD_LINKS"><STRONG>Subsections</STRONG></A>
+
+<UL>
+<LI><A NAME="tex2html601"
+ HREF="node40.html">A control input file</A>
+<LI><A NAME="tex2html602"
+ HREF="node41.html">A map input file</A>
+<LI><A NAME="tex2html603"
+ HREF="node42.html">A match input file</A>
+<LI><A NAME="tex2html604"
+ HREF="node43.html">An example of captured STDOUT</A>
+<LI><A NAME="tex2html605"
+ HREF="node44.html">A contig output file</A>
+<LI><A NAME="tex2html606"
+ HREF="node45.html">A grids output file</A>
+<LI><A NAME="tex2html607"
+ HREF="node46.html">A blocks file</A>
+</UL>
+<!--End of Table of Child-Links-->
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node4.html b/docs/fishmanual/node4.html
new file mode 100644
index 0000000..8437997
--- /dev/null
+++ b/docs/fishmanual/node4.html
@@ -0,0 +1,75 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Contact information</TITLE>
+<META NAME="description" CONTENT="Contact information">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="next" HREF="node5.html">
+<LINK REL="previous" HREF="node3.html">
+<LINK REL="up" HREF="node2.html">
+<LINK REL="next" HREF="node5.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html151"
+ HREF="node5.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html147"
+ HREF="node2.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html141"
+ HREF="node3.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html149"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html152"
+ HREF="node5.html">Legal information</A>
+<B> Up:</B> <A NAME="tex2html148"
+ HREF="node2.html">Getting started</A>
+<B> Previous:</B> <A NAME="tex2html142"
+ HREF="node3.html">Introduction</A>
+   <B> <A NAME="tex2html150"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H1><A NAME="SECTION00220000000000000000">
+Contact information</A>
+</H1>
+Please send questions, feedback, and bug reports to tjv at bio.unc.edu. The FISH website
+provides an online form where you may submit your email address should you wish to receive
+notification about updates to this software.
+
+<P>
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node40.html b/docs/fishmanual/node40.html
new file mode 100644
index 0000000..6f6b71b
--- /dev/null
+++ b/docs/fishmanual/node40.html
@@ -0,0 +1,119 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>A control input file</TITLE>
+<META NAME="description" CONTENT="A control input file">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="next" HREF="node41.html">
+<LINK REL="previous" HREF="node39.html">
+<LINK REL="up" HREF="node39.html">
+<LINK REL="next" HREF="node41.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html618"
+ HREF="node41.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html614"
+ HREF="node39.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html608"
+ HREF="node39.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html616"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html619"
+ HREF="node41.html">A map input file</A>
+<B> Up:</B> <A NAME="tex2html615"
+ HREF="node39.html">An example</A>
+<B> Previous:</B> <A NAME="tex2html609"
+ HREF="node39.html">An example</A>
+   <B> <A NAME="tex2html617"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H1><A NAME="SECTION00610000000000000000">
+A control input file</A>
+</H1>
+Shown is the complete ``control.txt" file. The filenames may be entered as
+paths. For example, if the map and match files were in a subdirectory named
+``data", the names would read, <I>e.g.</I> ``data<IMG
+ WIDTH="5" HEIGHT="17" ALIGN="BOTTOM" BORDER="0"
+ SRC="img29.png"
+ ALT="$ \/$">map1.txt" on a Unix system and
+would read ``data<!-- MATH
+ $\backslash$
+ -->
+<IMG
+ WIDTH="14" HEIGHT="37" ALIGN="MIDDLE" BORDER="0"
+ SRC="img30.png"
+ ALT="$ \backslash$">map1.txt" on a Windows system.
+<PRE>
+-maps
+1 data/map1.txt
+2 data/map2.txt
+3 data/map3.txt
+4 data/map4.txt
+5 data/map5.txt
+-matches
+1 1 data/match1v1.txt
+2 1 data/match2v1.txt
+3 1 data/match3v1.txt
+4 1 data/match4v1.txt
+5 1 data/match5v1.txt
+1 2 data/match1v2.txt
+2 2 data/match2v2.txt
+3 2 data/match3v2.txt
+4 2 data/match4v2.txt
+5 2 data/match5v2.txt
+1 3 data/match1v3.txt
+2 3 data/match2v3.txt
+3 3 data/match3v3.txt
+4 3 data/match4v3.txt
+5 3 data/match5v3.txt
+1 4 data/match1v4.txt
+2 4 data/match2v4.txt
+3 4 data/match3v4.txt
+4 4 data/match4v4.txt
+5 4 data/match5v4.txt
+1 5 data/match1v5.txt
+2 5 data/match2v5.txt
+3 5 data/match3v5.txt
+4 5 data/match4v5.txt
+5 5 data/match5v5.txt
+</PRE>
+
+<P>
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node41.html b/docs/fishmanual/node41.html
new file mode 100644
index 0000000..0357994
--- /dev/null
+++ b/docs/fishmanual/node41.html
@@ -0,0 +1,87 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>A map input file</TITLE>
+<META NAME="description" CONTENT="A map input file">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="next" HREF="node42.html">
+<LINK REL="previous" HREF="node40.html">
+<LINK REL="up" HREF="node39.html">
+<LINK REL="next" HREF="node42.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html630"
+ HREF="node42.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html626"
+ HREF="node39.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html620"
+ HREF="node40.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html628"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html631"
+ HREF="node42.html">A match input file</A>
+<B> Up:</B> <A NAME="tex2html627"
+ HREF="node39.html">An example</A>
+<B> Previous:</B> <A NAME="tex2html621"
+ HREF="node40.html">A control input file</A>
+   <B> <A NAME="tex2html629"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H1><A NAME="SECTION00620000000000000000">
+A map input file</A>
+</H1>
+Shown are the first ten lines from the chromosome 1 map file (``map.txt").
+The first column is the marker (in this case, gene) name, the second column is the
+transcriptional orientation.
+<PRE>
+At1g01010 1
+At1g01020 -1
+At1g01030 -1
+At1g01040 1
+At1g01050 -1
+At1g01060 -1
+At1g01070 -1
+At1g01080 -1
+At1g01090 -1
+At1g01100 -1
+</PRE>
+
+<P>
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node42.html b/docs/fishmanual/node42.html
new file mode 100644
index 0000000..14e0bf3
--- /dev/null
+++ b/docs/fishmanual/node42.html
@@ -0,0 +1,88 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>A match input file</TITLE>
+<META NAME="description" CONTENT="A match input file">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="next" HREF="node43.html">
+<LINK REL="previous" HREF="node41.html">
+<LINK REL="up" HREF="node39.html">
+<LINK REL="next" HREF="node43.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html642"
+ HREF="node43.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html638"
+ HREF="node39.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html632"
+ HREF="node41.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html640"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html643"
+ HREF="node43.html">An example of captured</A>
+<B> Up:</B> <A NAME="tex2html639"
+ HREF="node39.html">An example</A>
+<B> Previous:</B> <A NAME="tex2html633"
+ HREF="node41.html">A map input file</A>
+   <B> <A NAME="tex2html641"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H1><A NAME="SECTION00630000000000000000">
+A match input file</A>
+</H1>
+Shown is a sample of ten lines from the chromosome 1 vs. chromosome 1 match file
+(``match1v1.txt"). The scores shown are bit scores from TBLASTX.
+Note that with a MIN_SCORE of 200, all but the last match
+shown would be discarded.
+<PRE>
+At1g01030 At1g25560 112
+At1g01030 At1g50680 73
+At1g01030 At1g51120 72
+At1g01030 At1g35240 63
+At1g01030 At1g35520 60
+At1g01030 At1g77850 58
+At1g01030 At1g34310 58
+At1g01060 At1g18330 133
+At1g01060 At1g01520 109
+At1g01070 At1g11450 313
+</PRE>
+
+<P>
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node43.html b/docs/fishmanual/node43.html
new file mode 100644
index 0000000..c525b3e
--- /dev/null
+++ b/docs/fishmanual/node43.html
@@ -0,0 +1,197 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>An example of captured STDOUT</TITLE>
+<META NAME="description" CONTENT="An example of captured STDOUT">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="next" HREF="node44.html">
+<LINK REL="previous" HREF="node42.html">
+<LINK REL="up" HREF="node39.html">
+<LINK REL="next" HREF="node44.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html654"
+ HREF="node44.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html650"
+ HREF="node39.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html644"
+ HREF="node42.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html652"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html655"
+ HREF="node44.html">A contig output file</A>
+<B> Up:</B> <A NAME="tex2html651"
+ HREF="node39.html">An example</A>
+<B> Previous:</B> <A NAME="tex2html645"
+ HREF="node42.html">A match input file</A>
+   <B> <A NAME="tex2html653"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H1><A NAME="SECTION00640000000000000000">
+An example of captured STDOUT</A>
+</H1>
+By using the redirection operator, the output that FISH writes by
+default to the terminal is captured to a text file. In the sample output, this
+file is named ``fish_out.txt"
+<PRE>
+Fri Jun 27 11:15:47 2003
+FISH v1.0
+FISH is copyright ©2003, University of North Carolina at Chapel Hill
+Authors: Sugata Chakravarty and Todd J. Vision
+
+Control File = control.txt
+
+processing contigs
+ min_score = 200
+ max_dist = 10
+
+ contig msrkers features
+ 1 6494 5913
+ 2 4038 3711
+ 3 5221 4777
+ 4 3825 3467
+ 5 5888 5453
+
+writing contig output to contigs.txt
+
+
+processing matches
+ min_score = 200
+ top_hits = 5
+
+ contig1 contig2 points cells
+
+ 1 1 2143 17478828
+ 1 2 2018 21943144
+ 1 3 2088 28246400
+ 1 4 1538 20500372
+ 1 5 1986 32243588
+ 2 2 751 6883905
+ 2 3 1460 17727448
+ 2 4 1239 12866037
+ 2 5 1164 20236084
+ 3 3 849 11407476
+ 3 4 1300 16561859
+ 3 5 1977 26048980
+ 4 4 711 6008311
+ 4 5 1551 18905552
+ 5 5 1293 14864878
+
+writing grid output to grids.txt
+
+
+processing blocks
+ T = 0.05
+ total_points = 22068
+ total_features = 23321
+ total_cells = 271922816
+ probability h = 0.000081
+ d_T = 25.640781
+ min_edges = 2
+ block_prob = 0.00100
+ total_blocks = 508
+
+ contig1 contig2 blocks
+ 1 1 50
+ 1 2 52
+ 1 3 43
+ 1 4 34
+ 1 5 25
+ 2 2 27
+ 2 3 48
+ 2 4 48
+ 2 5 18
+ 3 3 15
+ 3 4 25
+ 3 5 53
+ 4 4 16
+ 4 5 33
+ 5 5 21
+
+writing output to blocks.txt
+
+block statistics
+
+points p-value frequency
+3 1.00e+00 |*********************************************
+**...243!
+4 9.22e-01 |********************************************
+***...83!
+5 1.17e-01 |***********************************35!
+6 6.02e-03 |*********************21
+7 2.94e-04 |**********************22
+8 1.43e-05 |*************13
+9 7.15e-07 |************12
+10 5.96e-08 |*****5
+11 0.00e+00 |************12
+12 0.00e+00 |**2
+13 0.00e+00 |****4
+14 0.00e+00 |*******7
+15 0.00e+00 |*****5
+16 0.00e+00 |***3
+17 0.00e+00 |***3
+18 0.00e+00 |**2
+19 0.00e+00 |****4
+20 0.00e+00 |***3
+21 0.00e+00 |***3
+22 0.00e+00 |**2
+23 0.00e+00 |****4
+24 0.00e+00 |*1
+25 0.00e+00 |*1
+26 0.00e+00 |****4
+27 0.00e+00 |*1
+28 0.00e+00 |**2
+29 0.00e+00 |*1
+30 0.00e+00 |**2
+31 0.00e+00 |**2
+34 0.00e+00 |*1
+40 0.00e+00 |*1
+44 0.00e+00 |*1
+60 0.00e+00 |*1
+66 0.00e+00 |*1
+79 0.00e+00 |*1
+ |----|----|----|----|----|----|----|----|--
+--|----|
+ 0 10 20 30 40
+ 50
+</PRE>
+
+<P>
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node44.html b/docs/fishmanual/node44.html
new file mode 100644
index 0000000..a6cca74
--- /dev/null
+++ b/docs/fishmanual/node44.html
@@ -0,0 +1,126 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>A contig output file</TITLE>
+<META NAME="description" CONTENT="A contig output file">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="next" HREF="node45.html">
+<LINK REL="previous" HREF="node43.html">
+<LINK REL="up" HREF="node39.html">
+<LINK REL="next" HREF="node45.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html666"
+ HREF="node45.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html662"
+ HREF="node39.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html656"
+ HREF="node43.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html664"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html667"
+ HREF="node45.html">A grids output file</A>
+<B> Up:</B> <A NAME="tex2html663"
+ HREF="node39.html">An example</A>
+<B> Previous:</B> <A NAME="tex2html657"
+ HREF="node43.html">An example of captured</A>
+   <B> <A NAME="tex2html665"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H1><A NAME="SECTION00650000000000000000">
+A contig output file</A>
+</H1>
+The opening lines of the file ``contigs.txt" are shown here.
+<PRE>
+Fri Jun 27 11:15:44 2003
+FISH v1.0
+FISH is copyright (c)2003, University of North Carolina
+ at Chapel Hill
+Authors: Sugata Chakravarty and Todd J. Vision
+
+-parameters
+ MIN_SCORE = 200
+ MAX_DIST = 10
+
+-contigs
+
+ contig markers features
+ 1 6494 5913
+ 2 4038 3711
+ 3 5221 4777
+ 4 3825 3467
+ 5 5888 5453
+
+
+
+-features
+
+ feature contig orientation genes
+ 0 1 1 At1g01010
+ 1 1 -1 At1g01020
+ 2 1 -1 At1g01030
+ 3 1 1 At1g01040
+ 4 1 -1 At1g01050
+ 5 1 -1 At1g01060
+ 6 1 -1 At1g01070
+ 7 1 -1 At1g01080
+ 8 1 -1 At1g01090
+ 9 1 -1 At1g01100
+ 10 1 1 At1g01110
+ 11 1 -1 At1g01120
+ 12 1 -1 At1g01130
+ 13 1 -1 At1g01140
+ 14 1 -1 At1g01150
+ 15 1 1 At1g01160
+ 16 1 -1 At1g01170
+ 17 1 1 At1g01180
+ 18 1 -1 At1g01190
+ 19 1 -1 At1g01200
+ 20 1 1 At1g01210
+ 21 1 1 At1g01220
+ 22 1 1 At1g01230
+ 23 1 1 At1g01240
+ . . . .
+ . . . .
+ . . . .
+</PRE>
+
+<P>
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node45.html b/docs/fishmanual/node45.html
new file mode 100644
index 0000000..f160732
--- /dev/null
+++ b/docs/fishmanual/node45.html
@@ -0,0 +1,128 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>A grids output file</TITLE>
+<META NAME="description" CONTENT="A grids output file">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="next" HREF="node46.html">
+<LINK REL="previous" HREF="node44.html">
+<LINK REL="up" HREF="node39.html">
+<LINK REL="next" HREF="node46.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html678"
+ HREF="node46.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html674"
+ HREF="node39.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html668"
+ HREF="node44.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html676"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html679"
+ HREF="node46.html">A blocks file</A>
+<B> Up:</B> <A NAME="tex2html675"
+ HREF="node39.html">An example</A>
+<B> Previous:</B> <A NAME="tex2html669"
+ HREF="node44.html">A contig output file</A>
+   <B> <A NAME="tex2html677"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H1><A NAME="SECTION00660000000000000000">
+A grids output file</A>
+</H1>
+The opening lines of the file ``grids.txt" are shown here.
+<PRE>
+Fri Jun 27 11:15:46 2003
+FISH v1.0
+FISH is copyright (c)2003, University of North Carolina
+ at Chapel Hill
+Authors: Sugata Chakravarty and Todd J. Vision
+
+Control File = control.txt
+
+-parameters
+ MIN_SCORE = 200
+ TOP_HITS = 5
+
+-subgrids
+ contig1 contig2 points cells
+ 1 1 2143 17478828
+ 1 2 2018 21943144
+ 1 3 2088 28246400
+ 1 4 1538 20500372
+ 1 5 1986 32243588
+ 2 2 751 6883905
+ 2 3 1460 17727448
+ 2 4 1239 12866037
+ 2 5 1164 20236084
+ 3 3 849 11407476
+ 3 4 1300 16561859
+ 3 5 1977 26048980
+ 4 4 711 6008311
+ 4 5 1551 18905552
+ 5 5 1293 14864878
+
+
+-points
+
+ point contig1 contig2 feat1 feat2 score
+ 0 1 1 6 954 328
+ 1 1 1 11 300 395
+ 2 1 1 11 616 237
+ 3 1 1 11 1668 665
+ 4 1 1 11 2146 580
+ 5 1 1 11 4808 582
+ 6 1 1 11 5050 326
+ 7 1 1 13 2412 290
+ 8 1 1 13 2499 303
+ 9 1 1 13 3263 401
+ 10 1 1 18 5288 207
+ 11 1 1 30 1288 588
+ 12 1 1 31 1355 549
+ 13 1 1 31 1699 553
+ 14 1 1 41 4440 242
+ 15 1 1 49 4531 273
+ . . . . . .
+ . . . . . .
+ . . . . . .
+</PRE>
+
+<P>
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node46.html b/docs/fishmanual/node46.html
new file mode 100644
index 0000000..6f66296
--- /dev/null
+++ b/docs/fishmanual/node46.html
@@ -0,0 +1,189 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>A blocks file</TITLE>
+<META NAME="description" CONTENT="A blocks file">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="previous" HREF="node45.html">
+<LINK REL="up" HREF="node39.html">
+<LINK REL="next" HREF="node47.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html688"
+ HREF="node47.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html684"
+ HREF="node39.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html680"
+ HREF="node45.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html686"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html689"
+ HREF="node47.html">Bibliography</A>
+<B> Up:</B> <A NAME="tex2html685"
+ HREF="node39.html">An example</A>
+<B> Previous:</B> <A NAME="tex2html681"
+ HREF="node45.html">A grids output file</A>
+   <B> <A NAME="tex2html687"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H1><A NAME="SECTION00670000000000000000"></A><A NAME="blocks"></A>
+<BR>
+A blocks file
+</H1>
+Selected lines from the file ``blocks.txt" are shown here.
+<PRE>
+Fri Jun 27 11:15:47 2003
+FISH v1.0
+FISH is copyright (c)2003, University of North Carolina
+ at Chapel Hill
+Authors: Sugata Chakravarty and Todd J. Vision
+
+Control File = control.txt
+
+-parameters
+ T = 0.05
+ total points = 22068
+ total_features = 23321
+ total_cells = 2.71923e+08
+ h = 8.11554e-05
+ d_T = 25.6408
+ Min_Block_Size = 3
+ block_prob = 0.001
+ total_blocks = 508
+
+
+-block 0
+ points contig1 contig2
+ 79 1 1
+
+ point dist markers orientation
+ 1040 0 {At1g19320 }{At1g75040 } 1
+ 1041 2 {At1g19330 }{At1g75060 } 1
+ 1042 3 {At1g19350 }{At1g75080 } 1
+ 1043 4 {At1g19360 }{At1g75110 At1g75120 } 1
+ 1044 3 {At1g19370 }{At1g75140 } 1
+ 1050 7 {At1g19400 }{At1g75180 } 1
+ 1056 8 {At1g19450 }{At1g75220 } 1
+ 1057 3 {At1g19480 }{At1g75230 } 1
+ 1058 11 {At1g19550 At1g19570 }{At1g75270 } 1
+ 1061 15 {At1g19650 }{At1g75370 } 1
+ 1062 2 {At1g19660 }{At1g75380 } 1
+ 1063 4 {At1g19680 }{At1g75400 } 1
+ 1064 3 {At1g19700 }{At1g75410 } 1
+ . . . .
+ . . . .
+ . . . .
+
+
+-block 1
+ points contig1 contig2
+ 30 1 1
+
+ point dist markers orientation
+ 1246 0 {At1g22920 }{At1g71230 } -1
+ 1249 12 {At1g22970 At1g22980 }{At1g71150 } -1
+ 1250 14 {At1g23010 }{At1g71040 } -1
+ 1251 4 {At1g23030 }{At1g71020 } -1
+ 1252 13 {At1g23080 }{At1g70940 } -1
+ 1256 7 {At1g23110 }{At1g70900 } -1
+ 1258 8 {At1g23140 }{At1g70800 At1g70810 } -1
+ 1262 6 {At1g23170 }{At1g70770 } -1
+ 1263 6 {At1g23190 }{At1g70730 } -1
+ 1265 4 {At1g23210 }{At1g70710 } -1
+ 1266 6 {At1g23240 }{At1g70670 At1g70680 } -1
+ 1267 3 {At1g23260 }{At1g70660 } -1
+ 1268 9 {At1g23290 }{At1g70600 } -1
+ . . . .
+ . . . .
+ . . . .
+ .
+ .
+ .
+-block 507
+ points contig1 contig2
+ 3 5 5
+
+ point dist markers orientation
+ 21978 0 {AT5g53950 }{AT5g61430 } 1
+ 21982 23 {AT5g54230 }{AT5g61420 } 1
+ 21988 21 {AT5g54380 }{AT5g61350 } -1
+
+
+-by contig
+ contig1 contig2 blocks
+ 1 1 50
+ 1 2 52
+ 1 3 43
+ 1 4 34
+ 1 5 25
+ 2 2 27
+ 2 3 48
+ 2 4 48
+ 2 5 18
+ 3 3 15
+ 3 4 25
+ 3 5 53
+ 4 4 16
+ 4 5 33
+ 5 5 21
+
+-by size
+ points obs exp p
+ 3 243 5.23e+01 1.00e+00
+ 4 83 2.55e+00 9.22e-01
+ 5 35 1.24e-01 1.17e-01
+ 6 21 6.04e-03 6.02e-03
+ 7 22 2.94e-04 2.94e-04
+ 8 13 1.43e-05 1.43e-05
+ 9 12 6.97e-07 7.15e-07
+ 10 5 3.40e-08 5.96e-08
+ 11 12 1.65e-09 0.00e+00
+ 12 2 8.05e-11 0.00e+00
+ . . . .
+ . . . .
+ . . . .
+ 44 1 0.00e+00 0.00e+00
+ 60 1 0.00e+00 0.00e+00
+ 66 1 0.00e+00 0.00e+00
+ 79 1 0.00e+00 0.00e+00
+</PRE>
+
+<P>
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node47.html b/docs/fishmanual/node47.html
new file mode 100644
index 0000000..19ee317
--- /dev/null
+++ b/docs/fishmanual/node47.html
@@ -0,0 +1,77 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Bibliography</TITLE>
+<META NAME="description" CONTENT="Bibliography">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
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+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
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+
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+<LINK REL="previous" HREF="node39.html">
+<LINK REL="up" HREF="fishmanual.html">
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+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html700"
+ HREF="node48.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html696"
+ HREF="fishmanual.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
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+ HREF="node46.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
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+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html701"
+ HREF="node48.html">About this document ...</A>
+<B> Up:</B> <A NAME="tex2html697"
+ HREF="fishmanual.html">User's Manual for FISH</A>
+<B> Previous:</B> <A NAME="tex2html691"
+ HREF="node46.html">A blocks file</A>
+   <B> <A NAME="tex2html699"
+ HREF="node1.html">Contents</A></B>
+<BR><BR>
+<!--End of Navigation Panel-->
+
+<H2><A NAME="SECTION00700000000000000000">
+Bibliography</A>
+</H2><DL COMPACT><DD><P></P><DT><A NAME="Calabrese2003">1</A>
+<DD> Calabrese PP, Chakravarty S, Vision TJ (2003) Fast
+identification and statistical evaluation of segmental homologies in comparative
+maps. <I>Bioinformatics</I> <B>19</B>, i74-i80.
+<P></P><DT><A NAME="Vision2000">2</A>
+<DD> TJ Vision, DG Brown, SD Tanksley (2000) The origins of
+genomic duplications in <I>Arabidopsis</I>. <I>Science</I> <B>290</B>:
+2114-2117.
+</DL>
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node48.html b/docs/fishmanual/node48.html
new file mode 100644
index 0000000..32a4b97
--- /dev/null
+++ b/docs/fishmanual/node48.html
@@ -0,0 +1,81 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>About this document ...</TITLE>
+<META NAME="description" CONTENT="About this document ...">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
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+
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+<LINK REL="up" HREF="fishmanual.html">
+</HEAD>
+
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+ SRC="file:/usr/share/latex2html/icons/next_g.png">
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+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
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+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html708"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Up:</B> <A NAME="tex2html707"
+ HREF="fishmanual.html">User's Manual for FISH</A>
+<B> Previous:</B> <A NAME="tex2html703"
+ HREF="node47.html">Bibliography</A>
+   <B> <A NAME="tex2html709"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H1><A NAME="SECTION00800000000000000000">
+About this document ...</A>
+</H1>
+ <STRONG>User's Manual for FISH
+<BR>(Fast Identification of Segmental Homology)</STRONG><P>
+This document was generated using the
+<A HREF="http://www.latex2html.org/"><STRONG>LaTeX</STRONG>2<tt>HTML</tt></A> translator Version 2002 (1.62)
+<P>
+Copyright © 1993, 1994, 1995, 1996,
+<A HREF="http://cbl.leeds.ac.uk/nikos/personal.html">Nikos Drakos</A>,
+Computer Based Learning Unit, University of Leeds.
+<BR>
+Copyright © 1997, 1998, 1999,
+<A HREF="http://www.maths.mq.edu.au/~ross/">Ross Moore</A>,
+Mathematics Department, Macquarie University, Sydney.
+<P>
+The command line arguments were: <BR>
+ <STRONG>latex2html</STRONG> <TT>fishmanual</TT>
+<P>
+The translation was initiated by root on 2003-06-27
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node5.html b/docs/fishmanual/node5.html
new file mode 100644
index 0000000..238383c
--- /dev/null
+++ b/docs/fishmanual/node5.html
@@ -0,0 +1,285 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Legal information</TITLE>
+<META NAME="description" CONTENT="Legal information">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
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+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
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+
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+<LINK REL="up" HREF="node2.html">
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+</HEAD>
+
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+<!--Navigation Panel-->
+<A NAME="tex2html163"
+ HREF="node6.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html159"
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+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
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+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
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+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html164"
+ HREF="node6.html">Acknowledgements</A>
+<B> Up:</B> <A NAME="tex2html160"
+ HREF="node2.html">Getting started</A>
+<B> Previous:</B> <A NAME="tex2html154"
+ HREF="node4.html">Contact information</A>
+   <B> <A NAME="tex2html162"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H1><A NAME="SECTION00230000000000000000">
+Legal information</A>
+</H1>
+FISH and its associated documentation are
+copyright ©2003, University of North Carolina at Chapel Hill. FISH is
+distributed in the hope that it will be useful but without any warranty whatsoever,
+even the implied warranty of merchantability or fitness for a particular purpose.
+Use of this software implies acceptance of the terms of the
+following license.
+
+<P>
+As used herein, the term, ``Program", below, refers to the source
+code and the derivatives supplied by the authors, and a ``work based on the
+Program" means either the Program or any derivative work under copyright law:
+that is to say, a work containing the Program or
+a portion of it, either verbatim or with modifications and/or translated
+into another language. (Hereinafter, translation is included without limitation
+in the term ``modification".) Each licensee is addressed as ``you".
+
+<P>
+1. SCOPE.
+Activities other than copying, distribution and modification are not
+covered by this License; they are outside its scope. The act of running the
+Program is not restricted, and the output from the Program is covered only
+if its contents constitute a work based on the Program (independent of having
+been made by running the Program). Whether that is true depends on what the
+Program does.
+
+<P>
+2. USER'S RIGHTS.
+You may copy and distribute verbatim copies of the Program's source code
+as you receive it, in any medium, provided that you keep intact all the notices
+that refer to this License and to the absence of any warranty; give any other
+recipients of the Program a copy of this License along with the Program;
+and conspicuously and appropriately publish on each copy a disclaimer of
+warranty and the following statement: ``Copyright ©2003, University of North
+Carolina at Chapel Hill" If the code has been modified, you also may include
+the following statement: ``Modified by [your institution]." You may charge a
+fee for the physical act of transferring a copy, and you may at your option
+offer warranty protection in exchange for a fee.
+
+<P>
+3. RIGHTS IN DERIVATIVE AND COMBINED WORKS.
+It is not the intent of this section to claim rights or contest
+your rights to work written entirely by you; rather, the intent is to exercise
+the right to control the distribution of derivative or collective works based
+on the Program. Aggregation of another work not based on the Program
+with the Program (or with a work based on the Program) on a volume of a storage
+or distribution medium does not bring the other work under the scope of this
+License.
+
+<P>
+You may modify your copy or copies of the Program or any portion of it,
+thus forming a work based on the Program, and copy and distribute such modifications
+or work under the terms of Section 2 above, provided that you also meet the following
+conditions:
+(a) You must cause the modified files to carry prominent notices stating that you
+changed the files and the date and nature of any change.
+(b) You must cause any work that you distribute or publish, that in whole
+or in part contains or is derived from the Program or any part thereof, to be
+licensed as a whole at no charge to all third parties under the terms of this License.
+
+<P>
+These requirements apply to the modified work as a whole. If identifiable
+sections of that work are not derived from the Program, and can be reasonably
+considered independent and separate works in themselves, then this License,
+and its terms, do not apply to those sections when you distribute them as
+separate works. But when you distribute the same sections as part of a whole
+which is a work based on the Program, the distribution of the whole must
+be on the terms of this License, whose permissions for other licensees extend
+to the entire whole, and thus to each and every part regardless of who wrote
+it.
+
+<P>
+4. USER'S PROVISION AND/OR DISTRIBUTION OF SOURCE CODE.
+You may copy and distribute the Program (or a work based on it, under
+Section 2) in object code or executable form under the terms of Sections
+1 and 2 above provided that you also accompany it with the complete corresponding
+machine-readable source code, which must be distributed under the terms of
+Sections 1 and 2 above on a medium customarily used for software interchange.
+
+<P>
+The source code for a work means the preferred form of the work for making
+modifications to it. For an executable work, complete source code means all
+the source code for all modules it contains, plus any associated interface
+definition files, plus the scripts used to control compilation and installation
+of the executable. However, as a special exception, the source code distributed
+need not include anything that is normally distributed (in either source
+or binary form) with the major components (compiler, kernel, and so on) of
+the operating system on which the executable runs, unless that component
+itself accompanies the executable. If distribution of executable or object code
+is made by offering access to copy from a designated place, then offering
+equivalent access to copy the source code from the same place counts as
+distribution of the source code, even though third parties are not compelled
+to copy the source along with the object code.
+
+<P>
+5. LICENSE RESTRICTIONS.
+(a) You may not copy, modify, sublicense, or distribute the Program
+except as expressly provided under this License. Any attempt otherwise to
+copy, modify, sublicense or distribute the Program is void, and will automatically
+terminate your rights under this License. However, parties who have received
+copies, or rights, from you under this License will not have their licenses
+terminated so long as such parties remain in full compliance.
+(b) You are not required to accept this License, since you have not
+signed it. However, nothing else grants you permission to modify or distribute
+the Program or its derivative works. These actions are prohibited by law
+if you do not accept this License. Therefore, by modifying or distributing
+the Program (or any work based on the Program), you indicate your acceptance
+of this License to do so, and all its terms and conditions for copying, distributing
+or modifying the Program or works based on it.
+(c) If, as a consequence of a court judgment or allegation of patent
+infringement or for any other reason (not limited to patent issues), conditions
+are imposed on you (whether by court order, agreement or otherwise) that
+contradict the conditions of this License, they do not excuse you from the
+conditions of this License. If you cannot distribute so as to satisfy simultaneously
+your obligations under this License and any other pertinent obligations,
+then as a consequence you may not distribute the Program at all. For example,
+if a patent license would not permit royalty-free redistribution of the Program
+by all those who receive copies directly or indirectly through you, then
+the only way you could satisfy both it and this License would be to refrain
+entirely from distribution of the Program.
+
+<P>
+It is not the purpose of this section to induce you to infringe any patents
+or other property right claims or to contest validity of any such claims;
+ this section has the sole purpose of protecting the integrity of the free
+software distribution system, which is implemented by public license practices.
+Many people have made generous contributions to the wide range of software
+distributed through that system in reliance on consistent application of
+that system; it is up to the author/donor to decide if he or she is willing
+to distribute software through any other system and a licensee cannot impose
+that choice.
+
+<P>
+6. LICENSE CONVEYS TO SUBSEQUENT RECIPIENTS.
+Each time you redistribute the Program (or any work based on the Program),
+the recipient automatically receives a license from the original licensor
+to copy, distribute or modify the Program subject to these terms and conditions.
+You may not impose any further restrictions on the recipients' exercise of
+the rights granted herein. You are not responsible for enforcing compliance
+by third parties to this License.
+
+<P>
+7. SEVERABILITY.
+If any portion of this license or any portion of any section of this
+license is held invalid or unenforceable under any particular circumstance,
+the balance of the section is intended to apply and the section as a whole
+is intended to apply in other circumstances.
+
+<P>
+8. NO WARRANTY.
+Because the program is licensed free of charge, there is no warranty
+for the program, to the extent permitted by applicable law. Except when otherwise
+stated in writing the copyright holders and/or other parties provide the
+program``as is" without warranty of any kind, either expressed or implied,
+including, but not limited to, the implied warranties of merchantability
+and fitness for a particular purpose. The entire risk as to the quality and
+performance of the program is with you. Should the program prove defective,
+you assume the cost of all necessary servicing, repair or correction.
+
+<P>
+In no event unless required by applicable law or agreed to in writing
+will any copyright holder, or any other party who may modify and/or redistribute
+the program as permitted above, be liable to you for damages, including any
+general, special, incidental or consequential damages arising out of the
+use or inability to use the program (including but not limited to loss of
+data or data being rendered inaccurate or losses sustained by you or third
+parties or a failure of the program to operate with any other programs),
+even if such holder or other party has been advised of the possibility of
+such damages. Because the program is licensed free of charge, there is no warranty
+for the program, to the extent permitted by applicable law. Except when otherwise
+stated in writing the copyright holders and/or other parties provide the
+program``as is" without warranty of any kind, either expressed or implied,
+including, but not limited to, the implied warranties of merchantability
+and fitness for a particular purpose. The entire risk as to the quality and
+performance of the program is with you. Should the program prove defective,
+you assume the cost of all necessary servicing, repair or correction.
+
+<P>
+In no event unless required by applicable law or agreed to in writing
+will any copyright holder, or any other party who may modify and/or redistribute
+the program as permitted above, be liable to you for damages, including any
+general, special, incidental or consequential damages arising out of the
+use or inability to use the program (including but not limited to loss of
+data or data being rendered inaccurate or losses sustained by you or third
+parties or a failure of the program to operate with any other programs),
+even if such holder or other party has been advised of the possibility of
+such damages.
+
+<P>
+<HR>
+<!--Navigation Panel-->
+<A NAME="tex2html163"
+ HREF="node6.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html159"
+ HREF="node2.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html153"
+ HREF="node4.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html161"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html164"
+ HREF="node6.html">Acknowledgements</A>
+<B> Up:</B> <A NAME="tex2html160"
+ HREF="node2.html">Getting started</A>
+<B> Previous:</B> <A NAME="tex2html154"
+ HREF="node4.html">Contact information</A>
+   <B> <A NAME="tex2html162"
+ HREF="node1.html">Contents</A></B>
+<!--End of Navigation Panel-->
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node6.html b/docs/fishmanual/node6.html
new file mode 100644
index 0000000..000bf57
--- /dev/null
+++ b/docs/fishmanual/node6.html
@@ -0,0 +1,78 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Acknowledgements</TITLE>
+<META NAME="description" CONTENT="Acknowledgements">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="next" HREF="node7.html">
+<LINK REL="previous" HREF="node5.html">
+<LINK REL="up" HREF="node2.html">
+<LINK REL="next" HREF="node7.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html175"
+ HREF="node7.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html171"
+ HREF="node2.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html165"
+ HREF="node5.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html173"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html176"
+ HREF="node7.html">Availability</A>
+<B> Up:</B> <A NAME="tex2html172"
+ HREF="node2.html">Getting started</A>
+<B> Previous:</B> <A NAME="tex2html166"
+ HREF="node5.html">Legal information</A>
+   <B> <A NAME="tex2html174"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H1><A NAME="SECTION00240000000000000000">
+Acknowledgements</A>
+</H1>
+Funding for FISH was provided by the USDA-ARS Center for Agricultural
+Bioinformatics, the Center for Computational Genomics at the Cornell
+Theory Center, and by National Science Foundation grants DBI-0110069 and DBI-0227314
+to TJV and DMS-0102008 to PPC.
+The authors wish to thank Peter Calabrese for his many contributions to the
+ideas underlying the software.
+
+<P>
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node7.html b/docs/fishmanual/node7.html
new file mode 100644
index 0000000..f126c4d
--- /dev/null
+++ b/docs/fishmanual/node7.html
@@ -0,0 +1,97 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Availability</TITLE>
+<META NAME="description" CONTENT="Availability">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="previous" HREF="node6.html">
+<LINK REL="up" HREF="node2.html">
+<LINK REL="next" HREF="node8.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html185"
+ HREF="node8.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html181"
+ HREF="node2.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html177"
+ HREF="node6.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html183"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html186"
+ HREF="node8.html">Installing from source code</A>
+<B> Up:</B> <A NAME="tex2html182"
+ HREF="node2.html">Getting started</A>
+<B> Previous:</B> <A NAME="tex2html178"
+ HREF="node6.html">Acknowledgements</A>
+   <B> <A NAME="tex2html184"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H1><A NAME="SECTION00250000000000000000">
+Availability</A>
+</H1>
+The latest version of this program, along with documentation and examples, is available from
+<TT><A NAME="tex2html1"
+ HREF="http://www.bio.unc.edu/faculty/vision/lab/FISH/">http://www.bio.unc.edu/faculty/vision/lab/FISH/</A></TT>.
+
+<P>
+FISH is written primarily in C++, together
+with C style data input/output. The source code is designed to be compatible
+with
+all versions of gcc (GNU C++/C compiler). In addition, executables are
+available
+for a limited number of platforms. The program may require 32 MB of RAM or more at runtime.
+
+<P>
+<BR><HR>
+<!--Table of Child-Links-->
+<A NAME="CHILD_LINKS"><STRONG>Subsections</STRONG></A>
+
+<UL>
+<LI><A NAME="tex2html187"
+ HREF="node8.html">Installing from source code</A>
+<LI><A NAME="tex2html188"
+ HREF="node9.html">Installing the Windows executable</A>
+<LI><A NAME="tex2html189"
+ HREF="node10.html">Installing the MacOSX executable</A>
+<LI><A NAME="tex2html190"
+ HREF="node11.html">Testing FISH on sample data</A>
+</UL>
+<!--End of Table of Child-Links-->
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node8.html b/docs/fishmanual/node8.html
new file mode 100644
index 0000000..422c271
--- /dev/null
+++ b/docs/fishmanual/node8.html
@@ -0,0 +1,95 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Installing from source code</TITLE>
+<META NAME="description" CONTENT="Installing from source code">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="next" HREF="node9.html">
+<LINK REL="previous" HREF="node7.html">
+<LINK REL="up" HREF="node7.html">
+<LINK REL="next" HREF="node9.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html201"
+ HREF="node9.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html197"
+ HREF="node7.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html191"
+ HREF="node7.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html199"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html202"
+ HREF="node9.html">Installing the Windows executable</A>
+<B> Up:</B> <A NAME="tex2html198"
+ HREF="node7.html">Availability</A>
+<B> Previous:</B> <A NAME="tex2html192"
+ HREF="node7.html">Availability</A>
+   <B> <A NAME="tex2html200"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H2><A NAME="SECTION00251000000000000000">
+Installing from source code</A>
+</H2>
+Installation from source code requires a c++ compiler (the makefile assumes that you have g++).
+Fish is known to successfully compile with g++ 3.1 and 3.2 (to see what version of
+g++ you have type ``g++ -v").
+
+<P>
+The code is
+known to compile and run on at least some versions of Solaris, RedHat Linux, Windows
+and MacOSX. It should compile and run on all systems
+with g++ installed. For windows environments, MinGW(http://www.mingw.org),
+provides a g++ compiler that works well. To install, type the following commands.
+
+<P>
+
+<OL>
+<LI>tar -xzvf FISH-1.0.tar.z
+</LI>
+<LI>cd FISH-1.0
+</LI>
+<LI>make all
+</LI>
+<LI>cp bin/fish /usr/local/bin (may require superuser priviliges)
+</LI>
+</OL>
+
+<P>
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/docs/fishmanual/node9.html b/docs/fishmanual/node9.html
new file mode 100644
index 0000000..673bea4
--- /dev/null
+++ b/docs/fishmanual/node9.html
@@ -0,0 +1,89 @@
+<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 3.2 Final//EN">
+
+<!--Converted with jLaTeX2HTML 2002 (1.62) JA patch-1.4
+patched version by: Kenshi Muto, Debian Project.
+LaTeX2HTML 2002 (1.62),
+original version by: Nikos Drakos, CBLU, University of Leeds
+* revised and updated by: Marcus Hennecke, Ross Moore, Herb Swan
+* with significant contributions from:
+ Jens Lippmann, Marek Rouchal, Martin Wilck and others -->
+<HTML>
+<HEAD>
+<TITLE>Installing the Windows executable</TITLE>
+<META NAME="description" CONTENT="Installing the Windows executable">
+<META NAME="keywords" CONTENT="fishmanual">
+<META NAME="resource-type" CONTENT="document">
+<META NAME="distribution" CONTENT="global">
+
+<META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=iso-8859-1">
+<META NAME="Generator" CONTENT="jLaTeX2HTML v2002 JA patch-1.4">
+<META HTTP-EQUIV="Content-Style-Type" CONTENT="text/css">
+
+<LINK REL="STYLESHEET" HREF="fishmanual.css">
+
+<LINK REL="next" HREF="node10.html">
+<LINK REL="previous" HREF="node8.html">
+<LINK REL="up" HREF="node7.html">
+<LINK REL="next" HREF="node10.html">
+</HEAD>
+
+<BODY >
+<!--Navigation Panel-->
+<A NAME="tex2html213"
+ HREF="node10.html">
+<IMG WIDTH="37" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="next"
+ SRC="file:/usr/share/latex2html/icons/next.png"></A>
+<A NAME="tex2html209"
+ HREF="node7.html">
+<IMG WIDTH="26" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="up"
+ SRC="file:/usr/share/latex2html/icons/up.png"></A>
+<A NAME="tex2html203"
+ HREF="node8.html">
+<IMG WIDTH="63" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="previous"
+ SRC="file:/usr/share/latex2html/icons/prev.png"></A>
+<A NAME="tex2html211"
+ HREF="node1.html">
+<IMG WIDTH="65" HEIGHT="24" ALIGN="BOTTOM" BORDER="0" ALT="contents"
+ SRC="file:/usr/share/latex2html/icons/contents.png"></A>
+<BR>
+<B> Next:</B> <A NAME="tex2html214"
+ HREF="node10.html">Installing the MacOSX executable</A>
+<B> Up:</B> <A NAME="tex2html210"
+ HREF="node7.html">Availability</A>
+<B> Previous:</B> <A NAME="tex2html204"
+ HREF="node8.html">Installing from source code</A>
+   <B> <A NAME="tex2html212"
+ HREF="node1.html">Contents</A></B>
+<BR>
+<BR>
+<!--End of Navigation Panel-->
+
+<H2><A NAME="SECTION00252000000000000000">
+Installing the Windows executable</A>
+</H2>
+
+<P>
+<PRE>
+INSTALLATION:
+ 1. Unzip FISH-1.0-win.zip into "C:\<DESIRED DIRECTORY>".
+ 2. The executable will be located in
+ "C:\<DESIRED DIRECTORY>\FISH-1.0\fish.exe".
+For Example:
+ Unzip to "C:\Program Files"
+ From a command line type: "C:\Program Files\FISH-1.0\fish.exe" -h.
+ Don't forget the quotations marks! This executes fish and shows
+ the command line options.
+
+REQUIREMENTS:
+ 1. 32 MB of RAM.
+ 2. Operating system: Known to run on Windows XP,ME, and NT.
+</PRE>
+
+<P>
+<BR><HR>
+<ADDRESS>
+root
+2003-06-27
+</ADDRESS>
+</BODY>
+</HTML>
diff --git a/makefile b/makefile
new file mode 100644
index 0000000..6c93456
--- /dev/null
+++ b/makefile
@@ -0,0 +1,16 @@
+CC = g++ -ggdb
+
+
+
+all : realall
+ make bin
+
+realall :
+ (cd ./src; $(CC) -c point.cpp; $(CC) fish.cpp point.o -o fish)
+
+bin :
+ mkdir bin
+ mv src/fish ./bin
+clean :
+ (cd src ; rm *.o)
+ (rm -rf ./bin)
diff --git a/sample_input/blk.out b/sample_input/blk.out
new file mode 100644
index 0000000..350bf23
--- /dev/null
+++ b/sample_input/blk.out
@@ -0,0 +1,6969 @@
+Wed Nov 19 13:23:03 2003
+FISH v1.0
+FISH is copyright (c)2003, University of North Carolina at Chapel Hill
+Authors: Sugata Chakravarty and Todd J. Vision
+
+Control File = control.txt
+
+-parameters
+ T = 0.05
+ total points = 22068
+ total_features = 23321
+ total_cells = 2.71923e+08
+ h = 8.11554e-05
+ d_T = 25.6408
+ Min_Block_Size = 3
+ block_prob = 0.001
+ total_blocks = 508
+
+
+-block 0
+ points contig1 contig2
+ 79 1 1
+
+ point dist markers orientation
+ 1040 0 {At1g19320 }{At1g75040 } 1
+ 1041 2 {At1g19330 }{At1g75060 } 1
+ 1042 3 {At1g19350 }{At1g75080 } 1
+ 1043 4 {At1g19360 }{At1g75110 At1g75120 } 1
+ 1044 3 {At1g19370 }{At1g75140 } 1
+ 1050 7 {At1g19400 }{At1g75180 } 1
+ 1056 8 {At1g19450 }{At1g75220 } 1
+ 1057 3 {At1g19480 }{At1g75230 } 1
+ 1058 11 {At1g19550 At1g19570 }{At1g75270 } 1
+ 1061 15 {At1g19650 }{At1g75370 } 1
+ 1062 2 {At1g19660 }{At1g75380 } 1
+ 1063 4 {At1g19680 }{At1g75400 } 1
+ 1064 3 {At1g19700 }{At1g75410 } 1
+ 1065 2 {At1g19710 }{At1g75420 } 1
+ 1068 7 {At1g19740 }{At1g75460 } 1
+ 1070 20 {At1g19840 }{At1g75590 } 1
+ 1073 6 {At1g19890 }{At1g75600 At1g75610 } 1
+ 1074 2 {At1g19900 }{At1g75620 } 1
+ 1075 2 {At1g19910 }{At1g75630 } 1
+ 1078 7 {At1g19940 }{At1g75680 } 1
+ 1079 3 {At1g19950 }{At1g75700 } 1
+ 1080 7 {At1g19970 }{At1g75760 } 1
+ 1082 6 {At1g20010 }{At1g75780 } 1
+ 1083 4 {At1g20030 }{At1g75800 } 1
+ 1084 9 {At1g20090 }{At1g75840 } 1
+ 1085 7 {At1g20120 At1g20130 }{At1g75880 At1g75890 At1g75900 } 1
+ 1091 11 {At1g20200 }{At1g75990 } 1
+ 1092 3 {At1g20220 }{At1g76020 } 1
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+ 1163 12 {At1g21170 At1g21180 }{At1g76850 } 1
+ 1164 4 {At1g21200 }{At1g76870 } 1
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+
+
+-block 1
+ points contig1 contig2
+ 30 1 1
+
+ point dist markers orientation
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+ 1303 6 {At1g23870 }{At1g70290 } -1
+ 1304 2 {At1g23880 }{At1g70280 } -1
+
+
+-block 2
+ points contig1 contig2
+ 28 1 1
+
+ point dist markers orientation
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+ 564 10 {At1g11160 }{At1g61210 } 1
+ 565 4 {At1g11170 }{At1g61240 } 1
+ 567 2 {At1g11180 }{At1g61250 } 1
+ 568 11 {At1g11250 }{At1g61290 } 1
+ 571 8 {At1g11280 At1g11300 At1g11330 At1g11340 At1g11350 At1g11410 }{At1g61360 At1g61370 At1g61380 At1g61390 At1g61400 At1g61420 At1g61430 At1g61440 At1g61460 At1g61480 At1g61490 At1g61500 At1g61550 At1g61610 } 1
+ 586 9 {At1g11310 }{At1g61560 } 1
+ 591 12 {At1g11390 }{At1g61640 } 1
+ 592 22 {At1g11540 }{At1g61740 } 1
+ 593 6 {At1g11560 }{At1g61790 } 1
+ 597 12 {At1g11630 }{At1g61870 } 1
+ 604 4 {At1g11670 }{At1g61890 } 1
+ 609 18 {At1g11740 }{At1g62050 } 1
+
+
+-block 3
+ points contig1 contig2
+ 26 1 1
+
+ point dist markers orientation
+ 981 0 {At1g18410 }{At1g73860 } 1
+ 984 9 {At1g18460 }{At1g73920 } 1
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+
+
+-block 4
+ points contig1 contig2
+ 25 1 1
+
+ point dist markers orientation
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+ 693 6 {At1g12780 }{At1g63180 } 1
+
+
+-block 5
+ points contig1 contig2
+ 22 1 1
+
+ point dist markers orientation
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+
+
+-block 6
+ points contig1 contig2
+ 20 1 1
+
+ point dist markers orientation
+ 911 0 {At1g17420 }{At1g72520 } 1
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+ 954 5 {At1g17940 }{At1g73390 } 1
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+
+
+-block 7
+ points contig1 contig2
+ 18 1 1
+
+ point dist markers orientation
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+
+
+-block 8
+ points contig1 contig2
+ 16 1 1
+
+ point dist markers orientation
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+
+
+-block 9
+ points contig1 contig2
+ 15 1 1
+
+ point dist markers orientation
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+
+
+-block 10
+ points contig1 contig2
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+
+ point dist markers orientation
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+
+
+-block 11
+ points contig1 contig2
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+
+ point dist markers orientation
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+
+
+-block 12
+ points contig1 contig2
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+
+ point dist markers orientation
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+
+
+-block 13
+ points contig1 contig2
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+
+ point dist markers orientation
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+
+
+-block 14
+ points contig1 contig2
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+
+ point dist markers orientation
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+ 376 3 {At1g09000 }{At1g54960 } 1
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+
+
+-block 15
+ points contig1 contig2
+ 7 1 1
+
+ point dist markers orientation
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+ 746 22 {At1g14220 }{At1g26820 } 1
+ 748 17 {At1g14320 }{At1g26910 } 1
+ 752 11 {At1g14370 }{At1g26970 } 1
+
+
+-block 16
+ points contig1 contig2
+ 7 1 1
+
+ point dist markers orientation
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+ 1223 4 {At1g22600 }{At1g72100 } -1
+ 1235 15 {At1g22650 }{At1g72000 } -1
+ 1237 17 {At1g22710 }{At1g71880 At1g71890 } -1
+ 1241 16 {At1g22760 }{At1g71770 } -1
+
+
+-block 17
+ points contig1 contig2
+ 7 1 1
+
+ point dist markers orientation
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+ 20457 22 {AT4g32920 }{AT5g11700 } 1
+
+
+-block 482
+ points contig1 contig2
+ 3 4 5
+
+ point dist markers orientation
+ 20587 0 {AT4g36030 }{AT5g66200 } 1
+ 20592 5 {AT4g36070 }{AT5g66210 } 1
+ 20601 18 {AT4g36160 }{AT5g66300 } 1
+
+
+-block 483
+ points contig1 contig2
+ 3 4 5
+
+ point dist markers orientation
+ 20629 0 {AT4g36890 }{AT5g67230 } -1
+ 20630 8 {AT4g36920 }{AT5g67180 } -1
+ 20631 8 {AT4g36950 }{AT5g67130 } -1
+
+
+-block 484
+ points contig1 contig2
+ 3 4 5
+
+ point dist markers orientation
+ 20668 0 {AT4g37750 }{AT5g57390 } -1
+ 20675 21 {AT4g37780 }{AT5g57620 } -1
+ 20680 8 {AT4g37800 }{AT5g57530 AT5g57540 AT5g57550 AT5g57560 } 1
+
+
+-block 485
+ points contig1 contig2
+ 3 4 5
+
+ point dist markers orientation
+ 20752 0 {AT4g39770 }{AT5g10100 } -1
+ 20755 10 {AT4g39800 }{AT5g10170 } 1
+ 20759 17 {AT4g39890 }{AT5g10260 } 1
+
+
+-block 486
+ points contig1 contig2
+ 3 4 5
+
+ point dist markers orientation
+ 20767 0 {AT4g39990 }{AT5g65270 } 1
+ 20773 12 {AT4g40030 AT4g40040 }{AT5g65350 AT5g65360 } 1
+ 20774 6 {AT4g40060 }{AT5g65310 } 1
+
+
+-block 487
+ points contig1 contig2
+ 21 5 5
+
+ point dist markers orientation
+ 21099 0 {AT5g10030 }{AT5g65210 } -1
+ 21100 10 {AT5g10090 }{AT5g65160 } 1
+ 21101 2 {AT5g10100 }{AT5g65140 } -1
+ 21102 12 {AT5g10140 }{AT5g65050 AT5g65060 } -1
+ 21105 11 {AT5g10220 AT5g10230 }{AT5g65020 } -1
+ 21106 2 {AT5g10240 }{AT5g65010 } -1
+ 21107 4 {AT5g10260 }{AT5g64990 } -1
+ 21111 4 {AT5g10270 }{AT5g64960 } -1
+ 21116 25 {AT5g10280 }{AT5g65230 } 1
+ 21121 2 {AT5g10290 }{AT5g65240 } 1
+ 21122 8 {AT5g10350 }{AT5g65260 } 1
+ 21124 13 {AT5g10390 AT5g10400 }{AT5g65350 AT5g65360 } 1
+ 21128 4 {AT5g10420 }{AT5g65380 } 1
+ 21129 6 {AT5g10440 }{AT5g65420 } 1
+ 21132 2 {AT5g10450 }{AT5g65430 } 1
+ 21133 5 {AT5g10470 }{AT5g65460 } 1
+ 21136 9 {AT5g10510 }{AT5g65510 } 1
+ 21139 3 {AT5g10520 }{AT5g65530 } 1
+ 21140 8 {AT5g10530 }{AT5g65600 } 1
+ 21141 3 {AT5g10540 }{AT5g65620 } 1
+ 21142 2 {AT5g10550 }{AT5g65630 } 1
+
+
+-block 488
+ points contig1 contig2
+ 20 5 5
+
+ point dist markers orientation
+ 20995 0 {AT5g07180 }{AT5g62230 } -1
+ 20999 17 {AT5g07220 }{AT5g62100 } -1
+ 21005 21 {AT5g07290 }{AT5g61960 } -1
+ 21006 6 {AT5g07300 }{AT5g61900 } -1
+ 21008 9 {AT5g07320 }{AT5g61810 } -1
+ 21009 4 {AT5g07340 }{AT5g61790 } -1
+ 21010 2 {AT5g07350 }{AT5g61780 } -1
+ 21011 4 {AT5g07370 }{AT5g61760 } -1
+ 21014 10 {AT5g07410 AT5g07420 AT5g07430 }{AT5g61680 } -1
+ 21016 5 {AT5g07450 }{AT5g61650 } -1
+ 21017 2 {AT5g07460 AT5g07470 }{AT5g61640 } -1
+ 21020 22 {AT5g07620 }{AT5g61570 } -1
+ 21021 14 {AT5g07660 }{AT5g61460 } -1
+ 21024 5 {AT5g07680 }{AT5g61430 } -1
+ 21028 2 {AT5g07690 AT5g07700 }{AT5g61420 } -1
+ 21030 4 {AT5g07710 }{AT5g61390 } -1
+ 21032 14 {AT5g07800 }{AT5g61290 } -1
+ 21034 7 {AT5g07830 }{AT5g61250 } -1
+ 21035 3 {AT5g07840 }{AT5g61230 } -1
+ 21037 4 {AT5g07880 }{AT5g61210 } -1
+
+
+-block 489
+ points contig1 contig2
+ 14 5 5
+
+ point dist markers orientation
+ 21145 0 {AT5g10580 }{AT5g24790 } 1
+ 21147 13 {AT5g10650 }{AT5g24870 } 1
+ 21148 15 {AT5g10740 }{AT5g24940 } 1
+ 21150 14 {AT5g10800 }{AT5g25060 } 1
+ 21151 3 {AT5g10820 }{AT5g25040 AT5g25050 } -1
+ 21152 7 {AT5g10840 }{AT5g25100 } 1
+ 21154 10 {AT5g10930 }{AT5g25110 } 1
+ 21158 21 {AT5g11060 }{AT5g25220 } 1
+ 21159 8 {AT5g11090 }{AT5g25280 } 1
+ 21162 7 {AT5g11130 }{AT5g25310 } 1
+ 21166 17 {AT5g11230 }{AT5g25400 } 1
+ 21173 9 {AT5g11300 }{AT5g25380 } -1
+ 21177 19 {AT5g11420 }{AT5g25460 } 1
+ 21178 7 {AT5g11430 }{AT5g25520 } 1
+
+
+-block 490
+ points contig1 contig2
+ 11 5 5
+
+ point dist markers orientation
+ 21041 0 {AT5g08190 }{AT5g23090 } 1
+ 21042 10 {AT5g08230 }{AT5g23150 } -1
+ 21043 6 {AT5g08250 }{AT5g23190 } 1
+ 21044 3 {AT5g08260 }{AT5g23210 } 1
+ 21045 2 {AT5g08270 }{AT5g23200 } 1
+ 21046 7 {AT5g08300 }{AT5g23250 } 1
+ 21048 12 {AT5g08340 }{AT5g23330 } 1
+ 21049 3 {AT5g08350 }{AT5g23350 AT5g23360 AT5g23370 } 1
+ 21050 9 {AT5g08390 }{AT5g23430 } -1
+ 21051 11 {AT5g08440 }{AT5g23490 } 1
+ 21057 15 {AT5g08500 }{AT5g23575 } 1
+
+
+-block 491
+ points contig1 contig2
+ 11 5 5
+
+ point dist markers orientation
+ 21081 0 {AT5g09670 }{AT5g64550 } 1
+ 21082 3 {AT5g09690 }{AT5g64560 } 1
+ 21084 2 {AT5g09700 AT5g09730 }{AT5g64570 } 1
+ 21086 7 {AT5g09740 }{AT5g64610 } 1
+ 21087 5 {AT5g09760 }{AT5g64640 } 1
+ 21088 2 {AT5g09770 }{AT5g64650 } 1
+ 21091 13 {AT5g09840 }{AT5g64710 } 1
+ 21094 6 {AT5g09870 }{AT5g64740 } 1
+ 21095 5 {AT5g09900 }{AT5g64760 } 1
+ 21096 11 {AT5g09930 }{AT5g64840 } 1
+ 21098 15 {AT5g10010 }{AT5g64910 } 1
+
+
+-block 492
+ points contig1 contig2
+ 10 5 5
+
+ point dist markers orientation
+ 21061 0 {AT5g08570 }{AT5g63680 } 1
+ 21062 5 {AT5g08590 }{AT5g63650 } -1
+ 21064 4 {AT5g08610 AT5g08620 }{AT5g63630 } -1
+ 21069 25 {AT5g09220 }{AT5g63850 } 1
+ 21070 7 {AT5g09260 }{AT5g63880 } 1
+ 21071 13 {AT5g09290 }{AT5g63980 AT5g64000 } 1
+ 21073 11 {AT5g09330 }{AT5g64060 } 1
+ 21074 3 {AT5g09350 }{AT5g64070 } 1
+ 21076 19 {AT5g09410 }{AT5g64220 } 1
+ 21078 24 {AT5g09540 }{AT5g64360 } 1
+
+
+-block 493
+ points contig1 contig2
+ 6 5 5
+
+ point dist markers orientation
+ 21181 0 {AT5g11590 }{AT5g25810 } 1
+ 21183 3 {AT5g11610 }{AT5g25820 } 1
+ 21184 12 {AT5g11670 }{AT5g25880 } 1
+ 21187 13 {AT5g11730 }{AT5g25970 } 1
+ 21189 21 {AT5g11830 }{AT5g26090 } 1
+ 21191 23 {AT5g12000 }{AT5g26150 } 1
+
+
+-block 494
+ points contig1 contig2
+ 5 5 5
+
+ point dist markers orientation
+ 21550 0 {AT5g26870 AT5g26950 }{AT5g27580 } -1
+ 21552 4 {AT5g26900 }{AT5g27570 } -1
+ 21554 11 {AT5g27000 }{AT5g27550 } -1
+ 21556 8 {AT5g27050 AT5g27070 }{AT5g27580 } 1
+ 21559 3 {AT5g27080 }{AT5g27570 } 1
+
+
+-block 495
+ points contig1 contig2
+ 4 5 5
+
+ point dist markers orientation
+ 20837 0 {AT5g02560 }{AT5g59870 } -1
+ 20839 4 {AT5g02570 }{AT5g59910 } -1
+ 20840 19 {AT5g02620 }{AT5g60070 } -1
+ 20853 21 {AT5g02810 }{AT5g60100 } 1
+
+
+-block 496
+ points contig1 contig2
+ 4 5 5
+
+ point dist markers orientation
+ 20986 0 {AT5g07070 }{AT5g58380 } 1
+ 20987 5 {AT5g07090 }{AT5g58420 } 1
+ 20988 5 {AT5g07120 }{AT5g58440 } 1
+ 20991 10 {AT5g07140 }{AT5g58520 } 1
+
+
+-block 497
+ points contig1 contig2
+ 4 5 5
+
+ point dist markers orientation
+ 21195 0 {AT5g12080 }{AT5g19520 } -1
+ 21202 4 {AT5g12110 }{AT5g19510 } -1
+ 21203 14 {AT5g12150 }{AT5g19390 } -1
+ 21204 6 {AT5g12180 }{AT5g19360 AT5g19450 } -1
+
+
+-block 498
+ points contig1 contig2
+ 3 5 5
+
+ point dist markers orientation
+ 21275 0 {AT5g15050 }{AT5g39990 } -1
+ 21285 17 {AT5g15120 }{AT5g39890 } 1
+ 21286 12 {AT5g15200 }{AT5g39850 } -1
+
+
+-block 499
+ points contig1 contig2
+ 3 5 5
+
+ point dist markers orientation
+ 21329 0 {AT5g16600 }{AT5g61420 } -1
+ 21335 6 {AT5g16640 }{AT5g61400 } 1
+ 21340 15 {AT5g16770 }{AT5g61420 } -1
+
+
+-block 500
+ points contig1 contig2
+ 3 5 5
+
+ point dist markers orientation
+ 21391 0 {AT5g18460 }{AT5g56530 } 1
+ 21400 21 {AT5g18610 }{AT5g56460 } 1
+ 21404 21 {AT5g18820 }{AT5g56500 } 1
+
+
+-block 501
+ points contig1 contig2
+ 3 5 5
+
+ point dist markers orientation
+ 21499 0 {AT5g24320 }{AT5g53500 } 1
+ 21502 10 {AT5g24380 }{AT5g53550 } 1
+ 21504 3 {AT5g24390 }{AT5g53570 } 1
+
+
+-block 502
+ points contig1 contig2
+ 3 5 5
+
+ point dist markers orientation
+ 21598 0 {AT5g29030 AT5g29040 }{AT5g32590 } -1
+ 21600 17 {AT5g30410 }{AT5g32520 AT5g32530 } 1
+ 21601 8 {AT5g30430 }{AT5g32590 } 1
+
+
+-block 503
+ points contig1 contig2
+ 3 5 5
+
+ point dist markers orientation
+ 21611 0 {AT5g34460 }{AT5g37080 AT5g37100 } 1
+ 21614 22 {AT5g34960 }{AT5g37110 } -1
+ 21615 25 {AT5g34970 AT5g35000 AT5g35010 }{AT5g36840 AT5g36850 AT5g36860 } -1
+
+
+-block 504
+ points contig1 contig2
+ 3 5 5
+
+ point dist markers orientation
+ 21700 0 {AT5g39680 }{AT5g40410 } -1
+ 21711 23 {AT5g39750 AT5g39810 }{AT5g40220 } -1
+ 21713 19 {AT5g39800 }{AT5g40080 } -1
+
+
+-block 505
+ points contig1 contig2
+ 3 5 5
+
+ point dist markers orientation
+ 21826 0 {AT5g44870 }{AT5g45200 AT5g45230 AT5g45250 } -1
+ 21827 15 {AT5g45050 }{AT5g45210 AT5g45260 } -1
+ 21828 2 {AT5g45060 }{AT5g45200 AT5g45230 AT5g45250 } -1
+
+
+-block 506
+ points contig1 contig2
+ 3 5 5
+
+ point dist markers orientation
+ 21924 0 {AT5g50510 }{AT5g50620 } 1
+ 21925 2 {AT5g50520 }{AT5g50630 } 1
+ 21926 2 {AT5g50530 }{AT5g50640 } 1
+
+
+-block 507
+ points contig1 contig2
+ 3 5 5
+
+ point dist markers orientation
+ 21978 0 {AT5g53950 }{AT5g61430 } 1
+ 21982 23 {AT5g54230 }{AT5g61420 } 1
+ 21988 21 {AT5g54380 }{AT5g61350 } -1
+
+
+-by contig
+ contig1 contig2 blocks
+ 1 1 50
+ 1 2 52
+ 1 3 43
+ 1 4 34
+ 1 5 25
+ 2 2 27
+ 2 3 48
+ 2 4 48
+ 2 5 18
+ 3 3 15
+ 3 4 25
+ 3 5 53
+ 4 4 16
+ 4 5 33
+ 5 5 21
+
+-by size
+ points obs exp p
+ 3 243 5.23e+01 1.00e+00
+ 4 83 2.55e+00 9.22e-01
+ 5 35 1.24e-01 1.17e-01
+ 6 21 6.04e-03 6.02e-03
+ 7 22 2.94e-04 2.94e-04
+ 8 13 1.43e-05 1.43e-05
+ 9 12 6.97e-07 7.15e-07
+ 10 5 3.40e-08 5.96e-08
+ 11 12 1.65e-09 0.00e+00
+ 12 2 8.05e-11 0.00e+00
+ 13 4 3.92e-12 0.00e+00
+ 14 7 1.91e-13 0.00e+00
+ 15 5 9.30e-15 0.00e+00
+ 16 3 4.53e-16 0.00e+00
+ 17 3 2.20e-17 0.00e+00
+ 18 2 1.07e-18 0.00e+00
+ 19 4 5.23e-20 0.00e+00
+ 20 3 2.54e-21 0.00e+00
+ 21 3 1.24e-22 0.00e+00
+ 22 2 6.03e-24 0.00e+00
+ 23 4 2.94e-25 0.00e+00
+ 24 1 1.43e-26 0.00e+00
+ 25 1 6.97e-28 0.00e+00
+ 26 4 3.39e-29 0.00e+00
+ 27 1 1.65e-30 0.00e+00
+ 28 2 8.04e-32 0.00e+00
+ 29 1 3.92e-33 0.00e+00
+ 30 2 1.91e-34 0.00e+00
+ 31 2 9.15e-36 0.00e+00
+ 34 1 0.00e+00 0.00e+00
+ 40 1 0.00e+00 0.00e+00
+ 44 1 0.00e+00 0.00e+00
+ 60 1 0.00e+00 0.00e+00
+ 66 1 0.00e+00 0.00e+00
+ 79 1 0.00e+00 0.00e+00
diff --git a/sample_input/check b/sample_input/check
new file mode 100644
index 0000000..32d2d51
--- /dev/null
+++ b/sample_input/check
@@ -0,0 +1,110 @@
+ARGS PROCESSED
+
+Wed Nov 19 13:08:24 2003
+FISH v1.0
+FISH is copyright ©2003, University of North Carolina at Chapel Hill
+Authors: Sugata Chakravarty and Todd J. Vision
+
+Control File = control.txt
+
+processing contigs
+ min_score = 200
+ max_dist = 10
+
+ contig msrkers features
+ 1 6494 5913
+ 2 4038 3711
+ 3 5221 4777
+ 4 3825 3467
+ 5 5888 5453
+
+processing matches
+ min_score = 200
+ top_hits = 5
+
+ contig1 contig2 points cells
+
+ 1 1 2143 17478828
+ 1 2 2018 21943144
+ 1 3 2088 28246400
+ 1 4 1538 20500372
+ 1 5 1986 32243588
+ 2 2 751 6883905
+ 2 3 1460 17727448
+ 2 4 1239 12866037
+ 2 5 1164 20236084
+ 3 3 849 11407476
+ 3 4 1300 16561859
+ 3 5 1977 26048980
+ 4 4 711 6008311
+ 4 5 1551 18905552
+ 5 5 1293 14864878
+
+processing blocks
+ T = 0.05
+ total_points = 22068
+ total_features = 23321
+ total_cells = 271922816
+ probability h = 0.000081
+ d_T = 25.640781
+ min_edges = 2
+ block_prob = 0.00100
+ total_blocks = 508
+
+ contig1 contig2 blocks
+ 1 1 50
+ 1 2 52
+ 1 3 43
+ 1 4 34
+ 1 5 25
+ 2 2 27
+ 2 3 48
+ 2 4 48
+ 2 5 18
+ 3 3 15
+ 3 4 25
+ 3 5 53
+ 4 4 16
+ 4 5 33
+ 5 5 21
+
+block statistics
+
+points p-value frequency
+3 1.00e+00 |***********************************************...243!
+4 9.22e-01 |***********************************************...83!
+5 1.17e-01 |***********************************35!
+6 6.02e-03 |*********************21
+7 2.94e-04 |**********************22
+8 1.43e-05 |*************13
+9 7.15e-07 |************12
+10 5.96e-08 |*****5
+11 0.00e+00 |************12
+12 0.00e+00 |**2
+13 0.00e+00 |****4
+14 0.00e+00 |*******7
+15 0.00e+00 |*****5
+16 0.00e+00 |***3
+17 0.00e+00 |***3
+18 0.00e+00 |**2
+19 0.00e+00 |****4
+20 0.00e+00 |***3
+21 0.00e+00 |***3
+22 0.00e+00 |**2
+23 0.00e+00 |****4
+24 0.00e+00 |*1
+25 0.00e+00 |*1
+26 0.00e+00 |****4
+27 0.00e+00 |*1
+28 0.00e+00 |**2
+29 0.00e+00 |*1
+30 0.00e+00 |**2
+31 0.00e+00 |**2
+34 0.00e+00 |*1
+40 0.00e+00 |*1
+44 0.00e+00 |*1
+60 0.00e+00 |*1
+66 0.00e+00 |*1
+79 0.00e+00 |*1
+ |----|----|----|----|----|----|----|----|----|----|
+ 0 10 20 30 40 50
diff --git a/sample_input/control.txt b/sample_input/control.txt
new file mode 100644
index 0000000..17c578c
--- /dev/null
+++ b/sample_input/control.txt
@@ -0,0 +1,33 @@
+-maps
+1 data/map1.txt
+2 data/map2.txt
+3 data/map3.txt
+4 data/map4.txt
+5 data/map5.txt
+-matches
+1 1 data/match1v1.txt
+2 1 data/match2v1.txt
+3 1 data/match3v1.txt
+4 1 data/match4v1.txt
+5 1 data/match5v1.txt
+1 2 data/match1v2.txt
+2 2 data/match2v2.txt
+3 2 data/match3v2.txt
+4 2 data/match4v2.txt
+5 2 data/match5v2.txt
+1 3 data/match1v3.txt
+2 3 data/match2v3.txt
+3 3 data/match3v3.txt
+4 3 data/match4v3.txt
+5 3 data/match5v3.txt
+1 4 data/match1v4.txt
+2 4 data/match2v4.txt
+3 4 data/match3v4.txt
+4 4 data/match4v4.txt
+5 4 data/match5v4.txt
+1 5 data/match1v5.txt
+2 5 data/match2v5.txt
+3 5 data/match3v5.txt
+4 5 data/match4v5.txt
+5 5 data/match5v5.txt
+end
diff --git a/sample_input/ctg.out b/sample_input/ctg.out
new file mode 100644
index 0000000..f591729
--- /dev/null
+++ b/sample_input/ctg.out
@@ -0,0 +1,25509 @@
+Wed Nov 19 13:23:00 2003
+FISH v1.0
+FISH is copyright (c)2003, University of North Carolina at Chapel Hill
+Authors: Sugata Chakravarty and Todd J. Vision
+
+-parameters
+ MIN_SCORE = 200
+ MAX_DIST = 10
+
+-contigs
+
+ contig markers features
+ 1 6494 5913
+ 2 4038 3711
+ 3 5221 4777
+ 4 3825 3467
+ 5 5888 5453
+
+
+
+-features
+
+ feature contig orientation genes
+ 0 1 1 At1g01010
+ 1 1 -1 At1g01020
+ 2 1 -1 At1g01030
+ 3 1 1 At1g01040
+ 4 1 -1 At1g01050
+ 5 1 -1 At1g01060
+ 6 1 -1 At1g01070
+ 7 1 -1 At1g01080
+ 8 1 -1 At1g01090
+ 9 1 -1 At1g01100
+ 10 1 1 At1g01110
+ 11 1 -1 At1g01120
+ 12 1 -1 At1g01130
+ 13 1 -1 At1g01140
+ 14 1 -1 At1g01150
+ 15 1 1 At1g01160
+ 16 1 -1 At1g01170
+ 17 1 1 At1g01180
+ 18 1 -1 At1g01190
+ 19 1 -1 At1g01200
+ 20 1 1 At1g01210
+ 21 1 1 At1g01220
+ 22 1 1 At1g01230
+ 23 1 1 At1g01240
+ 24 1 -1 At1g01250
+ 25 1 1 At1g01260
+ 26 1 1 At1g01280
+ 27 1 1 At1g01290
+ 28 1 1 At1g01300
+ 29 1 1 At1g01310
+ 30 1 -1 At1g01320
+ 30 1 -1 At1g01330
+ 31 1 -1 At1g01340
+ 32 1 1 At1g01350
+ 33 1 1 At1g01360
+ 34 1 1 At1g01370
+ 35 1 1 At1g01380
+ 36 1 -1 At1g01390
+ 36 1 -1 At1g01420
+ 37 1 -1 At1g01400
+ 38 1 1 At1g01410
+ 39 1 -1 At1g01430
+ 40 1 -1 At1g01440
+ 41 1 -1 At1g01450
+ 42 1 1 At1g01460
+ 43 1 -1 At1g01470
+ 44 1 1 At1g01480
+ 45 1 -1 At1g01490
+ 46 1 1 At1g01500
+ 47 1 1 At1g01510
+ 48 1 1 At1g01520
+ 49 1 -1 At1g01530
+ 50 1 1 At1g01540
+ 51 1 1 At1g01550
+ 52 1 1 At1g01560
+ 53 1 1 At1g01570
+ 54 1 1 At1g01580
+ 54 1 1 At1g01590
+ 55 1 1 At1g01600
+ 56 1 -1 At1g01610
+ 57 1 -1 At1g01620
+ 58 1 1 At1g01630
+ 59 1 -1 At1g01640
+ 60 1 -1 At1g01650
+ 61 1 -1 At1g01660
+ 62 1 -1 At1g01670
+ 63 1 -1 At1g01680
+ 64 1 1 At1g01690
+ 65 1 -1 At1g01700
+ 66 1 1 At1g01710
+ 67 1 1 At1g01720
+ 68 1 1 At1g01730
+ 69 1 -1 At1g01740
+ 70 1 1 At1g01750
+ 71 1 -1 At1g01760
+ 72 1 1 At1g01770
+ 73 1 1 At1g01780
+ 74 1 1 At1g01790
+ 75 1 1 At1g01800
+ 76 1 1 At1g01810
+ 77 1 -1 At1g01820
+ 78 1 -1 At1g01830
+ 79 1 1 At1g01840
+ 80 1 -1 At1g01850
+ 81 1 -1 At1g01860
+ 82 1 -1 At1g01880
+ 83 1 1 At1g01900
+ 84 1 -1 At1g01910
+ 85 1 1 At1g01920
+ 86 1 -1 At1g01930
+ 87 1 1 At1g01940
+ 88 1 1 At1g01950
+ 89 1 -1 At1g01960
+ 90 1 1 At1g01970
+ 91 1 -1 At1g01980
+ 92 1 -1 At1g01990
+ 93 1 1 At1g02000
+ 94 1 1 At1g02010
+ 95 1 -1 At1g02020
+ 96 1 -1 At1g02030
+ 97 1 -1 At1g02040
+ 98 1 -1 At1g02050
+ 99 1 -1 At1g02060
+ 100 1 -1 At1g02070
+ 101 1 1 At1g02080
+ 102 1 -1 At1g02090
+ 103 1 1 At1g02100
+ 104 1 1 At1g02110
+ 105 1 1 At1g02120
+ 106 1 -1 At1g02130
+ 107 1 -1 At1g02140
+ 108 1 1 At1g02150
+ 109 1 1 At1g02160
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diff --git a/sample_input/data/map1.txt b/sample_input/data/map1.txt
new file mode 100644
index 0000000..bb3aaf4
--- /dev/null
+++ b/sample_input/data/map1.txt
@@ -0,0 +1,6494 @@
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diff --git a/sample_input/data/map2.txt b/sample_input/data/map2.txt
new file mode 100644
index 0000000..9c9f3c4
--- /dev/null
+++ b/sample_input/data/map2.txt
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diff --git a/sample_input/data/map3.txt b/sample_input/data/map3.txt
new file mode 100644
index 0000000..75b3245
--- /dev/null
+++ b/sample_input/data/map3.txt
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diff --git a/sample_input/data/map4.txt b/sample_input/data/map4.txt
new file mode 100644
index 0000000..babc33d
--- /dev/null
+++ b/sample_input/data/map4.txt
@@ -0,0 +1,3825 @@
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diff --git a/sample_input/data/map5.txt b/sample_input/data/map5.txt
new file mode 100644
index 0000000..c489d17
--- /dev/null
+++ b/sample_input/data/map5.txt
@@ -0,0 +1,5888 @@
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diff --git a/sample_input/data/match1v1.txt b/sample_input/data/match1v1.txt
new file mode 100644
index 0000000..b3febc5
--- /dev/null
+++ b/sample_input/data/match1v1.txt
@@ -0,0 +1,44664 @@
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diff --git a/sample_input/data/match1v2.txt b/sample_input/data/match1v2.txt
new file mode 100644
index 0000000..33c7a86
--- /dev/null
+++ b/sample_input/data/match1v2.txt
@@ -0,0 +1,29477 @@
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diff --git a/sample_input/data/match1v3.txt b/sample_input/data/match1v3.txt
new file mode 100644
index 0000000..a3d84d2
--- /dev/null
+++ b/sample_input/data/match1v3.txt
@@ -0,0 +1,35011 @@
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diff --git a/sample_input/data/match1v4.txt b/sample_input/data/match1v4.txt
new file mode 100644
index 0000000..3e5467f
--- /dev/null
+++ b/sample_input/data/match1v4.txt
@@ -0,0 +1,28336 @@
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diff --git a/sample_input/data/match1v5.txt b/sample_input/data/match1v5.txt
new file mode 100644
index 0000000..0a0f944
--- /dev/null
+++ b/sample_input/data/match1v5.txt
@@ -0,0 +1,36799 @@
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diff --git a/sample_input/data/match2v1.txt b/sample_input/data/match2v1.txt
new file mode 100644
index 0000000..7f5dffc
--- /dev/null
+++ b/sample_input/data/match2v1.txt
@@ -0,0 +1,23897 @@
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diff --git a/sample_input/data/match2v2.txt b/sample_input/data/match2v2.txt
new file mode 100644
index 0000000..9dcf992
--- /dev/null
+++ b/sample_input/data/match2v2.txt
@@ -0,0 +1,20010 @@
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diff --git a/sample_input/data/match2v3.txt b/sample_input/data/match2v3.txt
new file mode 100644
index 0000000..0397043
--- /dev/null
+++ b/sample_input/data/match2v3.txt
@@ -0,0 +1,21496 @@
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diff --git a/sample_input/data/match2v4.txt b/sample_input/data/match2v4.txt
new file mode 100644
index 0000000..a52a0b5
--- /dev/null
+++ b/sample_input/data/match2v4.txt
@@ -0,0 +1,17409 @@
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diff --git a/sample_input/data/match2v5.txt b/sample_input/data/match2v5.txt
new file mode 100644
index 0000000..4a4c140
--- /dev/null
+++ b/sample_input/data/match2v5.txt
@@ -0,0 +1,20171 @@
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diff --git a/sample_input/data/match3v1.txt b/sample_input/data/match3v1.txt
new file mode 100644
index 0000000..d5e5d6d
--- /dev/null
+++ b/sample_input/data/match3v1.txt
@@ -0,0 +1,30768 @@
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diff --git a/sample_input/data/match3v2.txt b/sample_input/data/match3v2.txt
new file mode 100644
index 0000000..07154be
--- /dev/null
+++ b/sample_input/data/match3v2.txt
@@ -0,0 +1,22947 @@
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diff --git a/sample_input/data/match3v3.txt b/sample_input/data/match3v3.txt
new file mode 100644
index 0000000..81b7423
--- /dev/null
+++ b/sample_input/data/match3v3.txt
@@ -0,0 +1,32255 @@
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