Bug#640150:

[Nick Trew]

This appears to still be an issue:

Processing triggers for hicolor-icon-theme (0.13-1) ...

(gtk-update-icon-cache-3.0:20929): GdkPixbuf-WARNING **: Cannot open
pixbuf loader module file
'/usr/lib/x86_64-linux-gnu/gdk-pixbuf-2.0/2.10.0/loaders.cache': No
such file or directory

This likely means that your installation is broken.
Try running the command
  gdk-pixbuf-query-loaders >
/usr/lib/x86_64-linux-gnu/gdk-pixbuf-2.0/2.10.0/loaders.cache
to make things work again for the time being.

Thanks,
Nick